bluuebunny/crossref_metadata_2025_split huggingface dataset:
Identification and characterization of proteins, lipids, and metabolites in two organic fertilizer products derived from different nutrient sources
Authors: Li Jianyu , Zhao Xin , Bailey Laura S. , Kamat Manasi N. , Basso Kari B. 
Published: October 2021

AbstractThe biochemical composition of organic fertilizers largely determines their nutrient supply characteristics following soil application as well as their potential impact on soil microbial communities. Yet, limited information is available regarding the biochemical composition of organic fertilizers derived from different nutrient sources. Here, we qualitatively analyzed the presence and abundance of proteins, lipids, and metabolites in a liquid fish fertilizer (LFF) product and a type of granular organic fertilizer (GOF) commonly used in organic vegetable production, using liquid chromatography–tandem mass spectrometry (LC–MS/MS). Our results suggest that the presence and abundance of proteins, lipids, and metabolites differ greatly between GOF and LFF. The qualitative analysis shows LFF as a rich source of metabolites, while complex proteins and long-chain saturated fatty acids are dominant in GOF. The degree of biochemical composition complexity may help explain the varying impacts of different types of organic fertilizers on nutrient availability, soil health, and environmental quality.
Why consumers drink natural wine? Consumer perception and information about natural wine
Authors: Vecchio Riccardo , Parga-Dans Eva , Alonso González Pablo , Annunziata Azzurra 
Published: October 2021

AbstractSimilar to other foods, the concept of natural wine is much debated due to the lack of a clear and regulated definition, leading to a proliferation of heterogeneous norms and standards proposed from different natural wine associations at national levels. The current study explored the aspects which mediate individuals’ information and perception of natural wine, and the rationale behind natural wine consumption behavior among Italian (n= 501) and Spanish (n= 527) regular wine consumers. The results reveal a quite low self-reported degree of perceived information by Italian respondents and slightly higher levels among Spanish ones. The key drivers of natural wine consumption in both countries are wine consumption frequency, information, and natural product interest. In contrast, higher wine involvement levels decrease natural wine consumption frequency in both Italy and Spain. The findings also show that different perceptions lead to diverse motivations, suggesting the need for more homogeneous standards to mitigate the level of information asymmetry currently on the market.
Rapid range expansion predicted for the Common Grackle (Quiscalus quiscula) in the near future under climate change scenarios
Authors: Capainolo Peter , Perktaş Utku , Fellowes Mark D. E. 
Published: October 2021

Abstract
Background
Climate change due to anthropogenic global warming is the most important factor that will affect future range distribution of species and will shape future biogeographic patterns. While much effort has been expended in understanding how climate change will affect rare and declining species we have less of an understanding of the likely consequences for some abundant species. The Common Grackle (Quiscalus quiscula; Linnaeus 1758), though declining in portions of its range, is a widespread blackbird (Icteridae) species in North America east of the Rocky Mountains. This study examined how climate change might affect the future range distribution of Common Grackles.

Methods
We used the R package Wallace and six general climate models (ACCESS1-0, BCC-CSM1-1, CESM1-CAM5-1-FV2, CNRM-CM5, MIROC-ESM, and MPI-ESM-LR) available for the future (2070) to identify climatically suitable areas, with an ecological niche modelling approach that includes the use of environmental conditions.

Results
Future projections suggested a significant expansion from the current range into northern parts of North America and Alaska, even under more optimistic climate change scenarios. Additionally, there is evidence of possible future colonization of islands in the Caribbean as well as coastal regions in eastern Central America. The most important bioclimatic variables for model predictions were Annual Mean Temperature, Temperature Seasonality, Mean Temperature of Wettest Quarter and Annual Precipitation.

Conclusions
The results suggest that the Common Grackle could continue to expand its range in North America over the next 50 years. This research is important in helping us understand how climate change will affect future range patterns of widespread, common bird species.
The fast-track outpatient clinic significantly decreases hospitalisation rates among polymyalgia rheumatica patients
Authors: Chrysidis Stavros , Lage-Hansen Philip Rask , Svendsen Nikoletta , Diamantopoulos Andreas P. 
Published: October 2021

AbstractObjectivesThis study aimed to investigate the hospitalisation rates and the reasons for hospitalisation in patients with polymyalgia rheumatica (PMR). Furthermore, it aimed to clarify the impact of a newly established Fast Track Clinic (FTC) approach on hospitalisation rates in connection with PMR diagnosis.MethodsPatients diagnosed with PMR at South-West Jutland Hospital, Denmark, between 2013 and 2018 were included retrospectively. Only patients fulfilling the 2012 EULAR/ACR classification criteria were included in our cohort. An FTC for patients suspected of having PMR was established in the rheumatologic department of South-West Jutland Hospital in January 2018.ResultsOver 6 years (2013 to 2017), 254 patients were diagnosed with PMR, 56 of them while hospitalised. Hospitalised patients were more likely to have a higher initial CRP mean ± standard deviation (SD) 99.53 ± 59.36 vs 45.82 ± 36.96 mg/lt (p <  0.0001) and a shorter duration of symptoms (p = 0.0018). After implementing the FTC, a significant decrease in hospitalisation rates (from 20.4% to 3,5%) and inpatient days of care (mean ± SD 4.15 ± 3.1 vs 1 ± 0) were observed. No differences between the two groups were observed regarding clinical symptoms, laboratory values and initial prednisolone dose.ConclusionA substantial number of patients are hospitalised in connection with the PMR diagnosis. The FTC approach can decrease the hospitalisation rates significantly among these patients.Trial registrationRetrospectively registered.
Post-COVID-19 pulmonary fibrosis and its predictive factors: a prospective study
Authors: Nabahati Mehrdad , Ebrahimpour Soheil , Khaleghnejad Tabari Reza , Mehraeen Rahele 
Published: October 2021

Abstract
Background
We aimed to prospectively assess the lung fibrotic-like changes, as well as to explore their predictive factors, in the patients who survived Coronavirus Disease 2019 (COVID-19) infection. In this prospective cross-sectional study, we recruited patients who had been treated for moderate or severe COVID-19 pneumonia as inpatients and discharged from Rohani hospital in Babol, northern Iran, during March 2020. The clinical severity of COVID-19 pneumonia was classified as per the definition by World Health Organization. We also calculated the CT severity score (CSS) for all patients at admission. Within the 3 months of follow-up, the next chest CT scan was performed. As the secondary outcome, the patients with fibrotic abnormalities in their second CT scan were followed up in the next 3 months.

Results
Totally, 173 COVID-19 patients were finally included in the study, of whom 57 (32.9%) were male and others were female. The mean age was 53.62 ± 13.67 years old. At 3-month CT follow-up, evidence of pulmonary fibrosis was observed in 90 patients (52.0%). Consolidation (odds ratio [OR] = 2.84), severe disease (OR 2.40), and a higher CSS (OR 1.10) at admission were associated with increased risk of fibrotic abnormalities found at 3-month CT follow-up. Of 62 patients who underwent chest CT scan again at 6 months of follow-up, 41 patients (66.1%) showed no considerable changes in the fibrotic findings, while the rest of 21 patients (33.9%) showed relatively diminished lung fibrosis.

Conclusion
Post-COVID-19 lung fibrosis was observed in about half of the survivors. Also, patients with severe COVID-19 pneumonia were at a higher risk of pulmonary fibrosis. Moreover, consolidation, as well as a higher CSS, in the initial chest CT scan, was associated with increased risk of post-COVID-19 lung fibrosis. In addition, some patients experienced diminished fibrotic abnormalities in their chest CT on 6-month follow-up, while some others did not.
Chest radiographic score and lactate dehydrogenase are independent risk factors linked to mortality in Middle East Respiratory Syndrome Coronavirus (MERS-CoV) patients
Authors: Das Karuna M. , Singh Rajvir , Al Dossari Khalid , Subramanya Sandeep , Ojha Shreesh Kumar , AlMansoori Taleb , Alkoteesh Jamal Aldeen 
Published: October 2021

Abstract
Background
Despite the dominance of Covid-19 in the current situation, MERS-CoV is found infrequently in the Middle East. When coupled with the chest radiographic score, serum biochemical parameters may be utilized to assess serum biochemical changes in individuals with different degrees of MERS-CoV infection and to predict death. The purpose of this study was to examine the association between increased LDH levels and severe MERS-CoV outcomes utilizing ventilation days and an elevated chest radiographic score.

Results
Fifty-seven patients were included in the retrospective cohort. The mean age was 44.9 ± 13.5 years, while the range was between 12 and 73 years. With an average age of 53.3 ± 16.5 years, 18 of 57 (31.6%) patients were classified as deceased. The deceased group showed a substantially greater amount of LDH than the recovery group (280.18 ± 150.79 vs. 1241.72 ± 1327.77, p = 0.007). A cut-off value of > 512 LDH was established with a C-statistic of 0.96 (95% CI 0.92–1.00) and was 94% sensitive and 93% specific for mortality. Multivariate cox regression analysis revealed that loge (LDH) (adjusted HR: 9.91, 95% CI: 2.44–40.3, p = 0.001) and chest radiographic score (adjusted HR: 1.24, 95% CI: 1.05–1.47, p = 0.01) were risk factors for mortality, whereas ventilation days were a protective factor (adjusted HR: 0.84, 95% CI: 0.76–0.93, p = 0.001).

Conclusion
According to our results, blood LDH levels of > 512 had a 94% sensitivity and 93% specificity for predicting in-hospital mortality in patients infected with MERS-CoV. The chest radiographic score of 11.34 ± 5.4 was the risk factor for the mortality (adjusted Hazard ratio HR: 1.24, 95% CI: 1.05–1.47, p = 0.01). Thus, threshold may aid in the identification of individuals with MERS-CoV infection who die in hospital.
California sea lions employ task-specific strategies for active touch sensing
Authors: Milne Alyx O. , Orton Llwyd , Black Charlotte H. , Jones Gary C. , Sullivan Matthew , Grant Robyn A. 
Published: October 2021

ABSTRACT
Active sensing is the process of moving sensors to extract task-specific information. Whisker touch is often referred to as an active sensory system as whiskers are moved with purposeful control. Even though whisker movements are found in many species, it is unknown whether any animal can make task-specific movements with their whiskers. California sea lions (Zalophus californianus) make large, purposeful whisker movements and are capable of performing many whisker-related discrimination tasks. Therefore, California sea lions are an ideal species to explore the active nature of whisker touch sensing. Here, we show that California sea lions can make task-specific whisker movements. California sea lions move their whiskers with large amplitudes around object edges to judge size, make smaller, lateral stroking movements to judge texture and make very small whisker movements during a visual task. These findings, combined with the ease of training mammals and measuring whisker movements, makes whiskers an ideal system for studying mammalian perception, cognition and motor control.
MRI-directed biopsy for primary detection of prostate cancer in a population of 223 men: MRI In-Bore vs MRI-transrectal ultrasound fusion-targeted techniques
Authors: Del Monte Maurizio , Cipollari Stefano , Del Giudice Francesco , Pecoraro Martina , Bicchetti Marco , Messina Emanuele , Dehghanpour Ailin , Ciardi Antonio , Sciarra Alessandro , Catalano Carlo , Panebianco Valeria 
Published: October 2021

Objectives:
To compare the detection rates of overall prostate cancer (PCa) and clinically significant PCa (csPCa) and the median percentage of cancer per biopsy core between MRI-guided In-bore and MRI-TRUS fusion-targeted biopsy (TBx).

Methods:
In this retrospective study, 223 patients who underwent prostate multiparametric MRI (mpMRI) and subsequent MR-directed biopsy were included. For PCa and csPCa detection rate (DR), contingency tables were tested via the Pearson’s chi-squared to explore the variance of the outcome distribution. The percentage of cancer per biopsy core was tested with a two-tailed Mann-Withney test.

Results:
One hundred and seventeen and 106 patients underwent MRI-TRUS fusion or MRI In-bore TBx, respectively. 402 MRI biopsy targets were identified, of which 206 (51.2%) were biopsied with the MRI-TRUS TBx and 196 (48.8%) with the MRI In-bore TBx technique. Per-patient PCa and csPCa detection rates were 140/223 (62.8%) and 97/223 (43.5%), respectively. PCa-DR was 73/117 (62.4%) and 67/106 (63.2%) for MRI-TRUS and MRI In-Bore TBx (p = 0.9), while csPCa detection rate reached 50/117 (42.7%) and 47/106 (44.3%), respectively (p = 0.81). The median per-patient percentage of malignant tissue within biopsy cores was 50% (IQR: 27–65%) for PCa and 60% (IQR: 35–68%) for csPCa, with a statistically significant difference between the techniques.

Conclusion
No statistically significant difference in the detection rate of MRI In-bore and MRI-TRUS fusion TBx was found. MRI In-bore TBx showed higher per-core percentage of malignant cells.

Advances in knowledge
MRI In-bore biopsy might impact risk stratification and patient management considering the higher per-core percentage of malignant cells, especially for patients eligible for active surveillance or focal therapy.
Designing and developing an app to perform Hofstee cut-off calculations
Authors: Masters Ken , Al-Wardy Nadia 
Published: October 2021

Determining a Hofstee cut-off point in medical education student assessment is problematic: traditional methods can be time-consuming, inaccurate, and inflexible. To counter this, we developed a simple Android app that receives raw, unsorted student assessment data in .csv format, allows for multiple judges’ inputs, mean or median inputs, calculates the Hofstee cut-off mathematically, and outputs the results with other guiding information. The app contains a detailed description of its functionality.
Critical thinking, literature and teachers’ instructional activities: An Indonesian case of community service program for English teachers
Authors: Gandana Isti , Nafisah Nia , Imperiani Ernie 
Published: October 2021

Critical thinking (CT) has generally been known as one of the core competencies of the 21st-century skills that students need to acquire to succeed in today’s world. To attain this goal, teachers undoubtedly have a critical role to play. Involving a group of Indonesian teachers of English, this study aims to explore the teachers’ initial conceptions of critical thinking as reflected in their planned classroom activities. Specifically, the data collected were in the form of written instructional activities that used literary works as learning materials. These data were obtained following the teachers’ participation in an online workshop on promoting critical thinking through literature held for English teachers from MGMP (i.e., English Teachers Working Group) in Bandung Regency. The workshop introduced a model of teaching critical thinking skills using literary works and required the teachers to design their own instructional activities based on the proposed CT model. Adopting content analysis as the methodological tool to scrutinize the teachers’ prepared materials, our initial findings indicate that, in general, the teachers had inadequate knowledge of how to incorporate critical thinking skills into their teaching. Literature was seen merely as a tool to develop students’ linguistic abilities rather than as a way to explore humans’ experiences and to connect ‘the word and the world’. This study recommends that the teachers be given more time to better explore the concepts surrounding critical literacy pedagogy as well as be given more opportunities for practical application of the promoted instructional model.
Underwater fuel assembly deformation measurement with multisensor dual-line structured light
Authors: Wang Yukun , Ye Fan , Li Ji , Chen Xiaobo , Xi Juntong , Xu Xiaojin 
Published: October 2021

The fuel assembly is the core component of the nuclear energy system, and its excessive deformation will affect the normal insertion of the fuel rod and endanger safe operation of the reactor. In this paper, we present an underwater fuel assembly deformation measurement system based on 10 sets of visual measurement units. Benefitting from the waterproof design, the shielding-radiation design, the reflective structure design, the dual-optical line laser triangulation principle, and the underwater multilayer refractive geometry, the measurement system has shorter measurement time, higher measurement accuracy, and better environmental adaptability. Through the underwater field measurement and verification of the standard rod and fuel assembly, the bow deformation measurement accuracy of the measurement system is better than 0.3 mm, and the twist deformation measurement accuracy of the system is better than 0.15°. The proposed method allows transient and high-precision measurement in a certain irradiation dose and certain depth water, which provides a strong guarantee for measurement of fuel assembly deformation parameters in deep water and high radiation.
Investigation of strontium titanate spherical shell supported terahertz all-dielectric metamaterials
Authors: Leng Jin , Peng Jun , Wang Guangqing , He Xiaoyong , Lin Fangting , Liu Feng 
Published: October 2021

Based on the strontium titanate (

S
r
T
i
O

3

, STO) spherical shell all-dielectric metamaterials (ADMs) structure, the tunable propagation characteristics have been systematically studied, taking into account the effects of structural geometrical parameter, temperature, and graphene Fermi level. The results indicate that STO-based ADMs exhibit excellent thermally and electrically tunable performances, e.g., when the temperature rises from 77 to 400 K, the modulation depths (MDs) of resonant frequency and amplitude of the reflection dip reach 62% and 93%, and the absorption is tunable in the range of 0.7995–0.9017. Additionally, when the Fermi level of graphene changes from 0.1 to 1.0 eV, the amplitude MD of the reflection dip reaches 99.89%, and the absorption of the STO-based ADM increases from 0.8352 to 0.9953. These results provide a guide for understanding the resonant mechanism of STO-based ADMs and designing multifunctional terahertz devices.
PHARMACEUTICAL CARE FOR OLDER ADULTS IN BRAZIL: A SYSTEMATIC REVIEW
Authors: Zanetti Maria Olívia Barboza , Dos Santos Ana Flávia Miguel , Santos Débora Ferreira , Leira Pereira Leonardo Régis 
Published: October 2021

Considering the specific requirements of the older adults in the use of drugs and the opportunity for the clinical pharmacist to contribute to these patients, this review aimed to identify studies that have evaluated the results of pharmaceutical care for older adults in Brazil. We conducted a systematic review of the studies that answered the following guiding question: “What pharmaceutical care outcomes in older adult patients are found in Brazil?”. The search strategy was applied to the following databases in February 2019: PubMed, CENTRAL, BVS, and LILACS. Observational or experimental studies describing the results of pharmaceutical care in older adults in Brazil at any level of healthcare and related to the monitoring of any health problem were included. The quality of the included publications was assessed using the Downs and Black checklist. Of the 5080 studies that were identified, 11 were included. The results could summarize evidences supporting pharmaceutical care for older adults, regardless of place of attendance, health problem, or level of health care. The experiences of the Brazilians have contributed to the improvement of clinical and humanistic outcomes, such as reduction in blood pressure, glycemic index, lipid levels, anthropometric measurements, and polypharmacy; resolution of drugs related problems; and improvement in adherence and quality of life. One publication also reported economic outcomes (ICER per QALY gained). Although the number of articles obtained was small, they reported unanimously beneficial results. Pharmacist’s training in healthcare service is essential for expanding pharmaceutical care for this population group.
CARACTERIZAÇÃO DOS PROCESSOS DE COLETA E DESCARTE DE MEDICAMENTOS NA ATENÇÃO PRIMÁRIA DE UM MUNICÍPIO DO SERIDÓ ORIENTAL POTIGUAR
Authors: Beserra da Silva João , Mariz Batista Almária 
Published: October 2021

O descarte inadequado de medicamentos tende a impactar negativamente, do ponto de vista tanto de saúde pública quanto de preservação ambiental. Desta forma, este estudo teve como objetivo realizar um diagnóstico situacional dos processos de coleta e descarte de medicamentos na atenção primária do município de Currais Novos, RN, Brasil. Para tanto, procedeu-se à observação direta dos processos de coleta e descarte de medicamentos no município, considerando recursos humanos, físicos, econômicos e logísticos envolvidos, aliado à investigação da legislação pertinente em vigor. Em seguida, os dados foram tabulados e analisados via Microsoft Office Excel. Foram analisados 12 indicadores, sendo 10 (83%) não conformes e 2 (17%) conformes com a legislação vigente, no caso, não ocorrência de medicamentos com data de validade expirada nas prateleiras dos locais destinados a armazenamento destes no município e produtos recebidos são conferidos quanto a quantidade, validade e qualidade. Este diagnóstico servirá de subsídio para intervenção nas fragilidades detectadas neste estudo, a fim de enquadrar os processos de coleta e descarte de medicamentos em conformidade com a legislação vigente.
The optimization of Carreau model and rheological behavior of alumina/linear low-density polyethylene composites with different alumina content and diameter
Authors: Li Guo , Zhang Mitao , Ji Huajian , Ma Yulu , Chen Tao , Xie Linsheng 
Published: October 2021

Abstract
The influence of alumina (Al2O3) content and diameter on the viscosity characteristics of the alumina/linear low-density polyethylene (Al2O3/LLDPE) composites was discussed. The composites were fabricated by melt mixing with the two-rotor continuous mixer. The equivalent surface average particle diameter (

d
¯

A

{\bar{d}}_{\text{A}}

) of Al2O3 was calculated by the scanning electron microscopic (SEM) images of samples. The steady-state and dynamic rheological measurements were used to study the evolution of viscosity parameters. With the Carreau model fitting to the steady-rate rheological data, zero-shear viscosity η
0, time constant λ, and power law index n of composites were obtained. On this basis, an optimized Carreau model was established by studying the changes of these parameter values. The rheological result presented that the parameter values (η
0, λ, and n) were linearly proportional to the filling content of Al2O3 particles for nano-Al2O3/LLDPE composites. However, these parameters were, respectively, related to

d
¯

A

{\bar{d}}_{\text{A}}

,

d
¯

A

2

{\bar{d}}_{\text{A}}^{2}

, and

d
¯

A

3

{\bar{d}}_{\text{A}}^{3}

for micron-Al2O3/LLDPE composites.