bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Immungenicity and Cross-Neutralizing Activity of Enterovirus 71 Vaccine Candidate Strains
Authors: Xiao Xia , Zhou Kangping , Gu Meirong , Li Guoshun , Li Yuan , Liao Yuyi , Zeng Peiyu , Yu Yebin , Xu Yingzhi , Zhang Gaimei , Xiao Haifeng , Cai Kun , Xu Junqiang , Zhang Jikai , Liu Jiankai 
Published: September 2021

Objective:
This study aimed to evaluate enterovirus 71 (EV-A71) vaccine candidate strains, including their genotypes, immunogenicity and cross-neutralization capacity.

Methods:
From clinical samples, EV-A71 strains were separated by using Vero cells. Six strains were chosen for vaccine candidates, and the sequences were analyzed. To detect the immunogenicity of the strains, we used them to immunize NIH mice at 0 and 14 days. Cytopathic effects (CPE) were examined to determine the EV-A71 neutralizing antibody (NTAb) titer 14 d after the first and second inoculations. To evaluate the cross-neutralizing capacity of the EV-A71 vaccine candidate strains, we tested serum immunized mice with ten EV-A71 genotype strains.

Results:
Six EV-A71 vaccine candidate strains were identified, all belonging to sub-genotype C4, the prevalent genotype in China. The sequence similarity of the VP1 regions of the six candidate vaccine strains and three approved inactivated vaccines was 97.58%–97.77%, and the VP1 amino acid similarity was 98.65%–99.33%. Experiments were performed to evaluate the immunogenicity and cross-neutralizing activity of the EV-A71 vaccine candidate strains. The strains had good immunogenicity 14 d after two immunizations, inducing an NTAb titer ranging from 1:94 to 1:346. The NTAb seroconversion rates 14 d after one immunization were above 80% (except HB0007), and significantly increased immunogenicity of EV-A71 strains was observed post-inoculation. Furthermore, our candidate vaccine strains had broad cross-neutralizing activity after challenge with ten sub-genotypes of EV-A71. The highest NTAb titer/lowest NTAb titer ratios of sera against EV-A71 sub-genotypes were 8.0 (JS0002), 8.0 (JS0005), 21.3 (HB0005), 21.3 (HB0007), 10.7 (HB0040) and 8.0 (GD0002), respectively.

Conclusions:
Our EV-A71 strains had good immunogenicity and cross-neutralization activity, and have the potential to serve as vaccine strains for multivalent hand, foot and mouth disease vaccines.
A Review of the some aspects for the development of ZnO based photocatalysts for a variety of applications
Authors: Baibara O.E. , Radchenko M.V. , Karpyna V.A. , Ievtushenko A.I. 
Published: September 2021

Today, one of the most important problems for humanity is the pollution of the environment with various organic compounds that worsen the health of the peoples. The most dangerous pollutants are complex compounds that do not degrade under natural conditions. One way to solve the problem of pollution is to use photocatalysis to degrade harmful compounds. Zinc oxide nanostructures exhibit attractive photocatalytic and antibacterial properties due to the increased reactivity of the nanoparticle surface, which allows the efficient decomposition of organic pollutants. In this review, various methods for enhancing the photoefficiency of ZnO nanostructures are considered. It is shown that ZnO nanoparticles with specific surfaces (spherical, nanowires, nanoflowers), which are characterized by a high surface area, have a high removal rate of various pollutants. Such methods of improving the photocatalytic properties of ZnO as the band gap engineering, doping with metal/nonmetal, the combination of ZnO with other materials, formation of hybrid structures are considered.
Sebészi megoldások krónikus multivisceralis arteriás elzáródások esetében
Authors: Dzsinich Csaba , Barta László , Bogdány Klaudia , Tóth Tamás , Pataki Tibor , Nagy Gabriella 
Published: September 2021

Összefoglaló.
Bevezetés: A zsigeri artériák akut elzáródása fulmináns
klinikai képpel társul, és az esetek jelentős százalékában gyorsan halálhoz
vezet. Ha ezen artériák obliteratív folyamata lassan alakul ki, a zsigeri
artériák gazdag kollaterális kapacitása a klinikai tüneteket sokáig elfedi. Az
esetek egy részében az anatómiailag közel fekvő renalis artériák obliteratív
folyamata, illetve a társuló aortoiliacalis szűkületek és/vagy elzáródások
rendkívül szerteágazó klinikai képet okozhatnak. Az átfedések más hasi
betegségekkel félrevezetők lehetnek, emiatt késedelmes felismerésük súlyos
következményekkel járhat. Előfordulásuk nem gyakori, ismeretük azonban
nélkülözhetetlen mind a diagnosztika, mind a megoldás szempontjából.
Dolgozatunkban e bonyolult kórkép eseteit tárgyaljuk, és ismertetjük a
megoldások lehetőségeit.
Summary.
Introduction: Acute occlusions of the visceral arteries result
in fulminant clinical consequences and without fast and appropriate treatment
may lead to fatal outcome. If the obliterative disease has slow progression the
huge capacity of the collateral circulation of the visceral arteries may remain
free of symptoms at long run. By progression of the obliterative disease and
extension to both, the renal arteries and the aortoiliac segment the clinical
picture becomes more colourful. Symptoms mimicking other abdominal disorders may
easily lead to misdiagnosis and/or unnecessary delay of adequate treatment –
finally to organ or life threatening condition. In the present paper we deal
with this infrequent, but severe disease in order to recognize it in time, to
recommend proper diagnostic workup and propose adequate treatment.
Arrodált gyomorgyűrűk kezelése – irodalmi áttekintés egy eset kapcsán
Authors: Baranyai Zsolt , Merkel Keresztély , Horváth Miklós , Hritz István , Szijártó Attila 
Published: September 2021

Összefoglaló.
Bevezetés: 70 éves férfi beteg kóros kövérség (BMI: 50,1) miatt
2005-ben gyomorgyűrű beültetésben részesült. 2020 decemberében hasfali phlegmone
hátterében igazolt port infekció miatt más intézetben subcutan incisió, lavage
történt. CT-vizsgálattal, majd gasztroszkóppal a gyomorgyűrű arrosióját,
intramurális elhelyezkedését igazoltuk. A műtét során laparoszkópos technikával
a gyomor corpus nagygörbületén ejtett, kb. 2 cm nagyságú nyíláson keresztül
távolítottuk el a gyűrűt. A beteg szövődménymentesen került emisszióra.
Megbeszélés: Mintegy 20 évvel ezelőtt a laparoszkópos
állítható gyomorgyűrű (LAGB) rendkívül népszerű volt. A LAGB azonban számtalan
rövid és hosszú távú szövődménnyel jár, ezért egyre inkább kikerül a bariátriai
sebészet tárházából. A gyűrű arrosiója ritka, súlyos szövődmény. Eltávolításának
többféle módja lehet. A gyomorgyűrű eltávolítása általában a testsúly jelentős
növekedésével jár. A betegeknél konverziós bariátriai műtétet, laparoszkópos
gyomor sleeve reszekciót, vagy gyomor bypass műtétet lehet végezni.
Summary.
Introduction: Extreme obese (BMI: 50.1) 70 year old male
patient after LAGB procedure in 2005, with abdominal wall and port infection
underwent subcutaneous incision drainage of the area in December 2020. CT and
Gastroscopy confirmed gastric penetration and intramural position of the Band.
Using laparoscopic approach with incision of 2 cm of the stomach at the gastric
greater curvature the band had been removed. Patient had been discharged without
any complications. Discussion: LAGB was a very popular
bariatric approach at the first decade of laparoscopic bariatric surgery. The
increased incidence of short and long term complications reduced worldwide the
number of LAGB procedures. Band penetration is a rare but dangerous
complication. Laparoscopic removal is recommended. Usually, the intervention is
followed by significant weight gain which can be treated with conversion of LAGB
to Sleeve Gastrectomy or LGBP procedure.
Petersen-hernia, egy ritka sérvtípus megjelenése osztályunkon
Authors: Merkel Keresztély , Vass Tímea , Herczeg György , Ágh Péter , Máté Miklós 
Published: September 2021

Összefoglaló. 61 éves nőbeteg anamnéziséből 3 évvel korábbi, morbid
obezitás miatti bariátriai műtét (Roux Y gastric bypass, műtét előtti BMI 42,
aktuális BMI 22), hysterectomia, hypertonia említendő. Négy napja tartó diffúz
hasi fájdalom, hányás, hányinger, székletkimaradás miatt került SBO érintésével
sebészeti osztályunkra. Felvételkor mérsékelt hasi distenzió, diffúz felhasi
3-5/10 fájdalom volt, defensus nélkül, NG szonda jelentős tartalmat nem hozott.
Ileusra jellemző auscultációt, rectalis vizsgálattal üres ampullát találtunk.
Álló natív hasi felvételen jobb oldalon L II–III. csigolya mellett kissé gázos,
nem tágabb vékonybélkacs került leírásra, benne 2-3 cm-es nívóval. Hasi
UH-vizsgálaton folyadékkal telt, tág, 30–35 mm átmérőjű vékonybeleket írtak le.
CT-vizsgálat során a duodenum, jejunum és néhány proximalis ileumkacs kóros
distensióját igazolták, nívókkal, innen aboralisan összeesett vékonybeleket.
Tekintettel a kliniko-radiológiai képre, urgens műtét során Hasson-technikával
laparoszkópos inspekciót végeztünk, azonban a masszív ileus okozta térhiány
miatt kp medián laparotómiára konvertáltunk. Az exploráció során a
Petersen-hernián át a jobb hasfélbe herniálódott alimentáris, biliopancreatikus
és közös vékonybélszakaszt észleltünk a terminális ileum közepéig. A bél
életképesnek bizonyult. A Petersen-hernián át a kizáródott szakaszt a bal hasfél
felé visszahelyeztük, majd a Petersen-herniát nem felszívódó fonallal a colon
transversum és az alimentáris kacs mezentériuma közt tovafutó varrattal zártuk.
A beteg az ötödik postoperatív napon gyógyultan távozott.
Summary. 61 years old female with previous surgical history of
Roux-en-Y gastric bypass (3 years ago) and earlier hysterectomy admitted to our
surgical department with clinical and radiological signs of small intestinal
obstruction. Urgent intervention had been performed with following findings:
Petersen herniation of alimentary tract including the – biliopancreatic tract
and the small bowel extending to the midpart of the terminal ileum. Viability of
herniated intestinal tract had been confirmed, and reposition of herniated parts
through the Petersen hernia had been done. Closure with non-absorbable running
suture of the gap between the transverse colon and the mesenteriun of the
alimentary limb had been performed. Patient was fit for discharge on the fifth
postoperative day.
Associations between gaming disorder, parent-child relationship, parental supervision, and discipline styles: Findings from a school-based survey during the COVID-19 pandemic in Vietnam
Authors: Cuong Vu Manh , Assanangkornchai Sawitri , Wichaidit Wit , Minh Hanh Vu Thi , My Hanh Hoang Thi 
Published: September 2021

Abstract

Background and aims
Vietnam implemented numerous measures to reduce the transmission of COVID-19 among school students, including study-at-home/self-quarantine. During the study-at-home period, adolescents may engage in more video gaming than usual, potentially contributing to gaming disorder. However, the regionally-representative prevalence of gaming disorder and its association with parenting practice and discipline practice have not been described. We assessed the prevalence of gaming disorder among Vietnamese adolescents during the initial 6 months of the COVID-19 pandemic and the associations between gaming disorder and parenting practice and discipline practice.

Methods
We conducted a school-based, self-administered cross-sectional survey of 2,084 students in Hanoi, Vietnam (response rate = 97.1%). The survey included standardized instruments translated from English to Vietnamese. We performed multilevel logistic regressions to assess the associations between parenting practice, discipline practice, and gaming disorder.

Results
The prevalence of gaming disorder among the respondents was 11.6%. Healthy parent-child relationship was protective against gaming disorder (Adj OR = 0.36; 95% CI = 0.21, 0.62). Non-supervision, non-discipline, violent discipline were positively associated with gaming disorder.

Discussion and Conclusions
We found associations between gaming disorder and parent-child relationship, parental supervision, and parental discipline. Future interventional studies should consider assessing the effect of fostering healthy parent-child relationships and appropriate discipline on the occurrence or prognosis of gaming disorders.
Perfectionism predicts disordered eating and gambling via focused self-concept among those high in erroneous beliefs about their disordered behavior
Authors: Tabri Nassim , Werner Kaitlyn M. , Milyavskaya Marina , Wohl Michael J. A. 
Published: September 2021

AbstractBackground and aimsPerfectionism, a focused self-concept, and erroneous beliefs have been implicated in the development and maintenance of various disordered behaviors. However, researchers have yet to examine how these factors combine to explain different disordered behaviors. Herein, we addressed this gap and hypothesized a moderated-mediation model whereby perfectionism fosters the development of disordered behaviors through a focused self-concept. Critically, the effect of a focused self-concept on disordered behaviors is specific to people with erroneous beliefs about their disordered behaviors. The model was tested in the contexts of disordered gambling and disordered eating, particularly dietary restraint.MethodIn Study 1, participants were community members who gamble (N= 259). In Study 2, participants were university women (N= 219). In both studies, participants completed self-report measures of all constructs that are both reliable and valid.ResultsIn Study 1, as expected, there was a positive association between perfectionism and disordered gambling, which was mediated by financially focused self-concept. This mediation was only observed among participants who scored high on illusion of control and belief in luck. Likewise, in Study 2, there was a positive association between perfectionism and dietary restraint, which was mediated by appearance focused self-concept. The mediation effect was only observed among participants who believed that maladaptive dietary restraint behaviors were safe and efficacious.Discussion and ConclusionsThe findings support the transdiagnostic utility of our model, which may help explain an array of disordered behaviors, including other addictive behaviors as well as behaviors that involve rigid adherence to rules and control.
Improvement of the Structure and Content of an Annual Training Macrocycle for Young Pankration Athletes
Authors: Pityn Maryan , Sogor Oleg , Karatnyk Ivan , Hnatchuk Yaroslav , Blavt Oksana 
Published: September 2021

The study objective is to improve the structure and content of the annual training macrocycle for athletes aged from 15 to 16 years old in pankration, taking into account the specifics of their competitive performance.
Materials and methods. Theoretical analysis and generalization were used during work with literary sources on the problems of the research. Survey (questionnaire) was used for studying general approaches to the structure and content of young athletes’ training (aged from 15 to 16 years old) in pankration. There were also analyzed official programs for experienced pankration athletes which are used in Ukraine. Pedagogical experiment was held during September 2018 – July 2019. Its total duration was 10 months and 906 hours. Two identical six-month training macrocycles were performed. The control (21 athletes) and experimental (22 athletes) groups were formed.
Results. It was more effective for the development of technical and tactical actions and special physical fitness of young athletes aged from 15 to 16 years old. It was confirmed by significant intra-group increases in indicators of athletes’ preparedness (p≤0.05-0.01). The total number of significant changes in the experimental group (p≤0.05-0.01) during the first and second stages of the experiment was 12 of 13 indicators, and their values were higher than in the control group. In the control group, significant positive changes (p≤0.05-0.01) were found in 6 indicators during the first stage of the experiment and 8 – during the second one. After the second stage of the experiment athletes of the experimental group performed about half of the technical and tactical actions with a higher level of stability, economy, efficiency in various situations during sparring matches.
Conclusions. An experimental program made it possible to achieve an earlier deployment of adaptation processes to the specific physical activity available in training and competitive activities in pankration.
Volleyball Fundamental Movement Learning Model in Primary School
Authors: Samsudin Samsudin , Setiawan Iwan , Taufik Muhamad Syamsul , Solahuddin Soleh 
Published: September 2021

The study purpose. This study aims to develop a volleyball fundamental movement learning model with a game-centered approach and test its effectiveness in improving the volleyball learning outcomes of elementary school students
Materials and methods. The research method used is research and development (R&D) which adopts the10 steps of Borg and Gall R&D model. The data analysis techniques used in this study were qualitative and quantitative. This study used a pretest-posttest control group design to determine the initial abilities of the experimental and the control group (n = 40). The significance test of the learning model effectiveness used a t-test. Normality test was carried out before the data analysis on the results of the experimental group and the control group improvement in the fundamental movement of volleyball with the significance level = 0.05.
Results. The results of this study indicate a significant improvement for the experimental group data (0.97) and the control group data (0.42). Because the significance value of the two groups is more than 0.05, the overall data for the study group is normally distributed. The learning model effectiveness test results show the value of t-count -71.065.
Conclusions. The fundamental movement improvement of the experimental group is higher or more effective than that of the control group. So it can be concluded that the volleyball fundamental movement learning model with a game-centered approach is effective and efficient to be given to elementary school students.
Assessment of a Healthy Lifestyle and Quality of Life of Men and Women in Modern Society Based on SF-36
Authors: Krutsevich Tatiana , Trachuk Sergii , Ivanik Oksana , Panhelova Natalia , Brychuk Mariia , Kedrych Halyna 
Published: September 2021

Quality of life (QL) is defined as the subjective perception of one’s own well-being in a socio-cultural context, the satisfaction of one’s desires and the achievement of an ideal level of well-being. Quality of life is related to health (HRQOL), refers to the functioning and well-being in the physical, mental and social dimensions of life.
Research purpose: to analyze the main factors of quality of life of male and female population in modern Ukrainian society.
Material and Methods. 482 men and women aged 20-60 took part in sociological research.
The following research methods were used to solve the problemsset in the work: analysis and processing of special literature and data from the Internet; pedagogical observation; questionnaires (SF36); methods of mathematical statistics.
Results. The results of their own research show that the male population had a better quality of life on all scales of the SF-36 questionnaire compared to women (p <0.05). Respondents under the age of 20-29 had indicators of quality of life above average on the scales of physical and role physical functioning; pain in this age group did not have a significant impact on quality of life. The general state of health was assessed above the average level by respondents aged 20-29 and 30-39, regardless of gender, they were characterized by high scales of social activity and viability.
Conclusions. It is established that the indicator General health is a system-forming factor of quality of life for men and women in terms of the number of correlations. The obtained results allowed to determine the expediency and speed of implementation of preventive measures for men and women depending on the content of certain scales. Decreased overall health (GH) in men and women after the age of 50 significantly affects their quality of life, as evidenced by the large number of significant correlation coefficients. In women over 50 years of age, there is a sharp decrease in RP (role functioning due to physical condition) to 46 points, vital activity (VT) to 50 points, role functioning (due to emotional state) (RE) to 53 points. In men at this age, role functioning increases to 90 points, and social functioning (SF) to 89 points, which may indicate an uneven distribution of family and social functions in the lives of people of different sexes, overloading women with household chores, which prevents them from spending free time, affects the emotional state.
Prerequisites for the Development of Preventive Measures Against Office Syndrome Among Women of Working Age
Authors: Lazko Olga , Byshevets Nataliia , Kashuba Vitalii , Lazakovych Yuliia , Grygus Igor , Andreieva Nataliia , Skalski Dariusz 
Published: September 2021

The purpose of the article is to study prerequisites for the development of preventive measures against office syndrome among women of working age.
Material and methods. The research involved 52 female office employees 21 to 57 years old.
Results. The extended clustering of the original data using EM method with the performance of V-fold crosschecking has shown that female office employees are clearly divided into two clusters depending on the manifestation of office syndrome. Despite our assumptions, their division does not depend on age or length of service in the office, but on the manifestation of office syndrome and behavioral characteristics in the work process. Women assigned to different clusters are characterized by statistically significant (p < 0.05) differences between the level of pain in the joints and spine. The research has found that among female office employees with increased musculoskeletal pain, there are statistically significantly (p<0.05) more women with significant overweight and spinal diseases. They are less likely to take active breaks when working at a computer and a larger percentage of them use information technology for entertainment purposes outside the office for 3-4 hours a day. However, a smaller percentage of them work with a PC for more than 7 hours a day. Women with predominant musculoskeletal pain differ in their lifestyle and point to fundamentally different reasons that stop them from taking measures to prevent the risk of occupational diseases. In particular, among female office employees with no office syndrome, a statistically significant (p<0.05) larger share does not need to expand knowledge about the organization of health care in the office and among them the share of those who lead a passive lifestyle predominates.
Conclusions. Thus, these women are potentially at risk of developing office syndrome and, with the absence of preventive measures, are expected to move to the cluster of women with signs of office syndrome. The results of the research indicate the need for different approaches to planning health measures in the work environment, depending on the presence of office syndrome and the level of their responsible attitude to health in the work process.