bluuebunny/crossref_metadata_2025_split huggingface dataset:
KURT GÖDEL ON LOGICAL, THEOLOGICAL, AND PHYSICAL ANTINOMIES
Authors: LETHEN TIM 
Published: July 2021

AbstractThis paper presents hitherto unpublished writings of Kurt Gödel concerning logical, epistemological, theological, and physical antinomies, which he generally considered as “the most interesting facts in modern logic,” and which he used as a basis for his famous metamathematical results. After investigating different perspectives on the notion of the logical structure of the antinomies and presenting two “antinomies of the intensional,” a new kind of paradox closely related to Gödel’s ontological proof for the existence of God is introduced and completed by a compilation of further theological antinomies. Finally, after a presentation of unpublished general philosophical remarks concerning the antinomies, Gödel’s type-theoretic variant of Leibniz’Monadology, discovered in his notes on the foundations of quantum mechanics, is examined. Most of the material presented here has been transcribed from the Gabelsberger shorthand system for the first time.
Encouraging the scale-up of proven interventions: Infrastructure development for the “Evidence-to-Implementation” award
Authors: Quanbeck Andrew , Johnson Roberta A. , Saha-Muldowney Mondira , Resnik Felice , Hirschfield Sheena , Meline Rachael R. , Mahoney Jane E. 
Published: July 2021

AbstractBackground/Objective:Although most research universities offer investigators help in obtaining patents for inventions, investigators generally have few resources for scaling up non-patentable innovations, such as health behavior change interventions. In 2017, the dissemination and implementation (D & I) team at the University of Wisconsin’s Clinical and Translational Science Award (CTSA) created the Evidence-to-Implementation (E2I) award to encourage the scale-up of proven, non-patentable health interventions. The award was intended to give investigators financial support and business expertise to prepare evidence-based interventions for scale-up.Methods:The D & I team adapted a set of criteria named Critical Factors Assessment, which has proven effective in predicting the success of entrepreneurial ventures outside the health care environment, to use as review criteria for the program. In March 2018 and February 2020, multidisciplinary panels assessed proposals using a review process loosely based on the one used by the NIH for grant proposals, replacing the traditional NIH scoring criteria with the eight predictive factors included in Critical Factors Assessment.Results:two applications in 2018 and three applications in 2020 earned awards. Funding has ended for the first two awardees, and both innovations have advanced successfully.Conclusion:Late-stage translation, though often overlooked by the academic community, is essential to maximizing the overall impact of the science generated by CTSAs. The Evidence-to-implementation award provides a working model for supporting late-stage translation within a CTSA environment.
Keeping Each Other Safe: Who Checks on Their Neighbors During Weather Extremes in Summer and Winter?
Authors: Mason Lisa Reyes , Ekenga Christine C. 
Published: July 2021

AbstractObjective:Weather extremes are increasing with climate change and associated with higher morbidity and mortality. Promotion of social connections is an emerging area of research and practice for risk reduction during weather extremes. This study examines the practice of checking on neighbors during extreme summer heat and extreme winter weather. Objectives are to (1) describe the extent of neighbor checking during these extremes, and (2) examine factors associated with neighbor checking.Methods:We analyze survey data (n = 442) from a primarily low- and moderate- income study sample in a Southeastern U.S. city, using descriptive statistics and logistic regression.Results:About 17.6% of participants checked on neighbors during extreme summer heat, and 25.2% did so during extreme winter weather. Being middle or older aged and having more adverse physical health impacts were positively associated with neighbor checking, for both extremes. For winter only, having less education was positively associated with neighbor checking.Conclusions:Community-based partnerships for reducing risk during weather extremes may consider people who are older or have experienced their own adverse health impacts as initial target groups for promoting neighbor checking. Future research should also examine the motivations for, details about, and impacts of neighbor checking in greater depth.
Women’s Psychological Health, Family Function, and Social Support During Their Third Trimester of Pregnancy Within the COVID-19 Epidemic: A Cross-sectional Survey
Authors: He Dongning , Ren Jianhua , Luo Biru , Xiang Jie , Wang Guoyu , Gu Li , Chen Peng 
Published: July 2021

AbstractObjective:This study aims to investigate women’s psychological health, family function, and social support during the third trimester within the coronavirus disease 2019 (COVID-19) epidemic.Method:From January 30, 2020, to February 26, 2020, a total of 177 pregnant women during their third trimester (mean gestation time was 37.05 ± 4.06 wk) in a maternal and children’s hospital were investigated using the Self-Rating Anxiety Scale (SAS), the Edinburgh Postnatal Depression Scale, the Family APGAR Index, and the Perceived Social Support Scale. Nonparametric tests were conducted in the study. The statistical significance was set as P < 0.05.Result:The incidence rate of the participants’ anxiety and depression during the COVID-19 epidemic was 19.21% and 24.29%, respectively. The participants’ greatest concerns in the previous week were the risk of virus transmission (79.66%), and the prenatal examination and fetal growth (70.62%). The SAS ranks were higher in the participants who were concerned about the prenatal examination and fetal growth and work-related affairs.Conclusion:The participants’ psychological health was indirectly affected by the epidemic through the supply of medical resources and work-related factors. The medical staff should employ family support and social resources to guarantee the accessibility of medical services and living materials to decrease the pregnant women’s stress and further improve their psychological health.
Surnames and population structure in the Doctrine of Belén, Altos de Arica, Viceroyalty of Peru (1750–1813)
Authors: Alfaro Emma , Inostroza Xochitl , Dipierri José E. , Peña Aguilera Daniela , Hidalgo Jorge , Albeck María Esther 
Published: July 2021

AbstractThe analysis of multiple population structures (biodemographic, genetic and socio-cultural) and their inter-relations contribute to a deeper understanding of population structure and population dynamics. Genetically, the population structure corresponds to the deviation of random mating conditioned by a limited number of ancestors, by restricted migration in the social or geographic space, or by preference for certain consanguineous unions. Through the isonymic method, surname frequency and distribution across the population can supply quantitative information on the structure of a human population, as they constitute universal socio-cultural variables. Using documentary sources to undertake the Doctrine of Belén’s (Altos de Arica, Chile) historical demography reconstruction between 1763 and 1820, this study identified an indigenous population with stable patronymics. The availability of complete marriage, baptism and death records, low rates of migration and the significant percentage of individuals registered and constantly present in this population favoured the application of the isonymic method. The aim of this work was to use given names and surnames recorded in these documentary sources to reconstruct the population structure and migration pattern of the Doctrine of Belén between 1750 and 1813 through the isonymic method. The results of the study were consistent with the ethno-historical data of this ethnic space, where social cohesion was, in multiple ways, related to the regulation of daily life in colonial Andean societies.
ZAINICHIKOREANS, AFRICAN AMERICANS, AND THE RACIAL POLITICS OF COMPARISON
Authors: Robillard-Martel Xavier 
Published: July 2021

AbstractZainichiKoreans are the descendants of colonial subjects who migrated to Japan from 1910 to 1945, when Korea was part of the Japanese empire. In 1952, the Japanese state stripped them of their nationality status and left them stateless. Like racial minority groups in other societies, Korean descendants still face systemic discrimination in contemporary Japan. Although they were colonized by a non-European power and are not physically distinct from the dominant Japanese population, their situation is often compared to that of African Americans. Yet, for scholars who think that race is necessarily based on “phenotype,” anti-Korean oppression cannot qualify as an instance of racism in Japan and the comparison with Black Americans is misguided. This article explores the intellectual and political issues at stake in debates over the use of racial comparisons—what I call the “racial politics of comparison.” Examining the views of scholars andZainichiKorean activists, I show how the latter have drawn inspiration from the Black liberation struggle and built alliances with African Americans in order to resist oppression. I argue that their unique situation forces us to revise the role attributed to phenotype in current definitions of race and racism.
The Contrasting Effects of Education on Fertility over Time Casalguidi, 1819–1960
Authors: Manfredini Matteo , Breschi Marco , Fornasin Alessio 
Published: July 2021

AbstractEducation has been frequently claimed to shape demographic outcomes. Mortality, fertility, and nuptiality have all been attested to be affected to some extent by education attainment. This article investigates the effects of education on fertility over time in a rural Italian community once controlled for potential confounders. Using individual-level data drawn from various sources, the study analyzes the role of education in shaping reproductive behaviors not only during the demographic transition (1890–1960) but also in the pretransitional period (1819–59). The results highlight the contrasting effects of literacy on fertility, which passed from a positive association in the ancien régime to a negative one in the transitional phase. Educated couples were therefore forerunners in the process of fertility decline because they were not only in the position to be the most pressed to control reproduction but also because they were likely aware of reproductive mechanisms, had the knowledge of more effective birth-control methods, had the economic possibility to get them, and had the necessary capacity to use them.
Coupled Mg/Ca and Clumped Isotope Measurements Indicate Lack of Substantial Mixed Layer Cooling in the Western Pacific Warm Pool During the Last ∼5 Million Years
Authors: Meinicke N. , Reimi M. A. , Ravelo A. C. , Meckler A. N. 
Published: July 2021

AbstractThe Indo‐Pacific Warm Pool (IPWP) plays a crucial role in influencing climate dynamics both in the tropics and globally. Yet, there is an ongoing controversy concerning the evolution of surface temperatures in the IPWP since the Pliocene, which is fueled by contradictory proxy evidence. Temperature reconstructions using TEX86 indicate a gradual cooling by ∼2°C from the Pliocene to today while Mg/Ca‐based studies using planktonic foraminifera do not report any long‐term trends. A bias in Mg/Ca records due to seawater chemistry changes has been suggested as an explanation for this proxy mismatch. Here, we present data from two independent foraminifera‐based temperature proxies, Mg/Ca and clumped isotopes (Δ47), measured on the same samples from IODP Site U1488 in the IPWP. We reconstructed mixed layer and subsurface temperatures and find very good agreement among Mg/Ca and Δ47 when applying a minor correction for changing Mg/Ca ratios of seawater. Diagenetic effects could influence Δ47 but the evaluation of foraminifera preservation at Site U1488 suggests that this effect is unlikely to have masked a long‐term trend in the data. While remaining uncertainties prevent us from fully ruling out particular hypotheses, our study adds evidence that mixed layer temperatures likely did not cool substantially, while subsurface temperatures cooled more strongly since the Pliocene. The substantial Pleistocene cooling previously observed in TEX86 data is consistent with this finding when interpreting it as a combined surface and subsurface signal.
Ionospheric Echo Detection in Digital Ionograms Using Convolutional Neural Networks
Authors: De La Jara C. , Olivares C. 
Published: July 2021

AbstractAn ionogram is a graph of the time that a vertically transmitted wave takes to return to the earth as a function of frequency. Time is typically represented as virtual height, which is the time divided by the speed of light. The ionogram is shaped by making a trace of this height against the frequency of the transmitted wave. Along with the echoes of the ionosphere, ionograms usually contain a large amount of noise and interference of different nature that must be removed in order to extract useful information. In the present work, we propose a method based on convolutional neural networks to extract ionospheric echoes from digital ionograms. Extraction using the CNN model is compared with extraction using machine learning techniques. From the extracted traces, ionospheric parameters can be determined and electron density profile can be derived.
An Analytical Baseflow Coefficient Curve for Depicting the Spatial Variability of Mean Annual Catchment Baseflow
Authors: Cheng Shujie , Cheng Lei , Liu Pan , Qin Shujing , Zhang Lu , Xu Chong‐Yu , Xiong Lihua , Liu Liu , Xia Jun 
Published: July 2021

AbstractCatchment baseflow is jointly controlled by climate and landscape properties. Previous studies have recognized that spatial variability of mean annual baseflow coefficient (BFC = , ratio of baseflow to precipitation) is primarily controlled by aridity index and storage capacity. However, an analytical solution of BFC in terms of the dominant controlling factors has not yet been established. The objective of this study was to develop an analytical BFC curve to depict spatial variability of BFC based on the “limit” concept of the Budyko framework. The BFC curve relates the baseflow coefficient to aridity index and storage capacity without resolving complex interactions between evapotranspiration and baseflow generation. The proposed BFC curve showed that, in the arid catchments, baseflow coefficient was primarily limited by available water (precipitation, P) and, in the humid catchments, was jointly controlled by both the available energy (potential evapotranspiration, Ep) and catchment retention capability (ratio of catchment storage capacity to P, i.e., Sp/P). Observed hydrological data from 950 catchments in Australia, the conterminous United States and the United Kingdom with diverse hydro‐climatic conditions (BFC = 0.001–0.650) were collected to demonstrate the capability of the developed curve. Results showed that the BFC curve captured the spatial variability of observed BFC in the 950 study catchments (R2 = 0.75, RMSE = 0.058). Mean annual baseflow estimated by the BFC curve agreed well with observed baseflow (R2 = 0.86, RMSE = 0.19 mm). The developed analytical curve provides an analytical solution for understanding how aridity index and storage capacity control mean annual catchment baseflow, and will improve predictability of baseflow at ungauged basins.
Bias Corrected Estimation of Paleointensity (BiCEP): An Improved Methodology for Obtaining Paleointensity Estimates
Authors: Cych Brendan , Morzfeld Matthias , Tauxe Lisa 
Published: July 2021

AbstractThe assumptions of paleointensity experiments are violated in many natural and archeological materials, leading to Arai plots which do not appear linear and yield inaccurate paleointensity estimates, leading to bias in the result. Recently, paleomagnetists have adopted sets of “selection criteria” that exclude specimens with nonlinear Arai plots from the analysis, but there is little consensus in the paleomagnetic community on which set to use. In this study, we present a statistical method we call Bias Corrected Estimation of Paleointensity (BiCEP), which assumes that the paleointensity recorded by each specimen is biased away from a true answer by an amount that is dependent a single metric of nonlinearity (the curvature parameter) on the Arai plot. We can use this empirical relationship to estimate the recorded paleointensity for a specimen where, that is, a perfectly straight line. We apply the BiCEP method to a collection of 30 sites for which the true value of the original field is well constrained. Our method returns accurate estimates of paleointensity, with similar levels of accuracy and precision to restrictive sets of paleointensity criteria, but accepting as many sites as permissive criteria. The BiCEP method has a significant advantage over using these selection criteria because it achieves these accurate results without excluding large numbers of specimens from the analysis. It yields accurate, albeit imprecise estimates from sites whose specimens all fail traditional criteria. BiCEP combines the accuracy of the strictest selection criteria with the low failure rates of the less reliable “loose” criteria.
Biomass Burning Smoke and Its Influence on Clouds Over the Western U. S.
Authors: Twohy Cynthia H. , Toohey Darin W. , Levin Ezra J. T. , DeMott Paul J. , Rainwater Bryan , Garofalo Lauren A. , Pothier Matson A. , Farmer Delphine K. , Kreidenweis Sonia M. , Pokhrel Rudra P. , Murphy Shane M. , Reeves J. Michael , Moore Kathryn A. , Fischer Emily V. 
Published: July 2021

AbstractSmall cumulus clouds over the western United States were measured via airborne instruments during the wildfire season in summer of 2018. Statistics of the sampled clouds are presented and compared to smoke aerosol properties. Cloud droplet concentrations were enhanced in regions impacted by biomass burning smoke, at times exceeding 3,000 cm−3. Images and elemental composition of individual smoke particles and cloud droplet residuals are presented and show that most are dominantly organic, internally mixed with some inorganic elements. Despite their high organic content and relatively low hygroscopicity, on average about half of smoke aerosol particles >80 nm diameter formed cloud droplets. This reduced cloud droplet size in small, smoke‐impacted clouds. A number of complex and competing climatic impacts may result from wide‐spread reductions in cloud droplet size due to wildfires prevalent across the region during summer months.
Petrogenesis of Himalayan Leucogranites: Perspective From a Combined Elemental and Fe‐Sr‐Nd Isotope Study
Authors: Shi Qingshang , He Yongsheng , Zhao Zhidan , Liu Dong , Harris Nigel , Zhu Di‐Cheng 
Published: July 2021

AbstractThe petrogenesis of Himalayan leucogranites remains crucial for understanding the thermal and tectonic evolution of the Himalayan orogen. To understand whether they are largely pristine melts of crustal anatexis or have experienced a high degree of fractional crystallization (FC), we present Fe isotopic data of 30 representative Himalayan leucogranites and 9 local metasedimentary rocks. Excepting three garnet leucogranites with low δ56Fe (−0.04‰–0.06‰) that are likely affected by garnet accumulation, tourmaline, and two‐mica leucogranites have largely homogeneous δ56Fe from 0.13‰ to 0.24‰ irrespective of their highly variable SiO2, MgO, and FeOt contents. Combined with observed mineral assemblages and available fractionation factors, this does not support a high degree of FC (with or without assimilation) in their petrogenesis. The elevated δ56Fe relative to the supposed source rocks, represented by metasedimentary rocks and/or metabasite with a δ56Fe value of 0.10‰, by ∼0.07‰, may reflect Fe isotope fractionation during crustal anatexis. This study indicates most leucogranites can provide robust constraints on the conditions of crustal anatexis and thus the thermal and tectonic evolution of the Himalayan orogen.
C5aR1-positive neutrophils promote breast cancer glycolysis through WTAP-dependent m6A methylation of ENO1
Authors: Ou Baochi , Liu Yuan , Yang Xiaowei , Xu Xiaojun , Yan Yunwen , Zhang Jingjie 
Published: July 2021

AbstractNeutrophils are significant compositions of solid tumors and exert distinct functions in different types of tumors. However, the precise role of neutrophils in the progression of breast cancer (BC) is presently unclear. In this study, by investigating the single-cell RNA sequencing data, we identify a new neutrophil subset, C5aR1-positive neutrophils, that correlates with tumor progression and poor survival for BC patients. Furthermore, it is discovered that C5aR1-positive neutrophils enhance BC cell glycolysis via upregulating ENO1 expression. Mechanically, C5aR1-positive neutrophil-secreted IL1β and TNFα cooperatively activate ERK1/2 signaling, which phosphorylates WTAP at serine341 and thereby stabilizes WTAP protein. The stabilization of WTAP further promotes RNA m6A methylation of ENO1, impacting the glycolytic activity of BC cells. Importantly, C5aR1-positive neutrophils also promote breast cancer growth in vivo, and this effect is abolished by WTAP silencing. In clinical BC samples, increased C5aR1-positive neutrophils correlate with elevated IL1β, TNFα, and ENO1 expression. A high co-expression of C5aR1-positive neutrophil gene signature and ENO1 predicts worse prognosis of BC patients compared with a low co-expression. Collectively, our study reveals a novel subset of C5aR1-positive neutrophils that induces breast cancer glycolysis via increasing ERK1/2-WTAP-dependent m6A methylation of ENO1. These findings support the potential for exploration of C5aR1-positive neutrophils as a therapeutic target in breast cancer.
CircPVT1 promotes gallbladder cancer growth by sponging miR-339-3p and regulates MCL-1 expression
Authors: Wang Shouhua , Su Ting ting , Tong Huanjun , Shi Weibin , Ma Fei , Quan Zhiwei 
Published: July 2021

AbstractCircular RNAs (circRNAs) have been implicated in modulating biological processes in some tumors. However, the contributions and molecular mechanisms of circRNAs to gallbladder cancer (GBC) remain largely unknown. In the present study, our results showed circPVT1 expression was significantly upregulated in GBC tissues and cells. Higher circPVT1 expression was correlated with lymph node metastasis, advanced TNM stage, and poor overall survival (OS) in patients with GBC. Subsequently, knockdown of circPVT1 significantly impeded GBC cell proliferation, migration, invasion, while induced cell apoptosis in vitro. However, upregulated circPVT1 had the opposite effects. In vivo, we also demonstrated that knockdown of circPVT1 inhibited tumor growth. Furthermore, we confirmed that circPVT1 could regulate Myeloid cell leukemia-1 (MCL-1) expression by sponging to miR-339-3p, which affected tumor progression in GBC cells. In summary, our findings indicated that circPVT1 may serve as a promising prognostic marker and therapeutic target for GBC.