bluuebunny/crossref_metadata_2025_split huggingface dataset:
Small hydropower dam site suitability modelling in upper Benue river watershed, Nigeria
Authors: Odiji Caleb , Adepoju Matthew , Ibrahim Idris , Adedeji Oluwatola , Nnaemeka Ihenacho , Aderoju Olaide 
Published: July 2021

AbstractSmall hydropower (SHP) is one of the most critical renewable energy that is well adapted to the rural localities in less developed countries across the world. Most rural communities in Nigeria are off the national power grid and are bedevilled by an inconsistent supply of electricity. The one possible panacea to the rural energy crisis is harnessing the terrain and abundant rivers and streams within their domain. This study aimed to identify and select suitable sites for the SHP dam in the upper Benue river watershed. Ten thematic layers, land use, precipitation, geology, soil, slope, elevation, stream power index, topographic wetness index, drainage density, and flow, were integrated with Geographic information system and Analytical hierarchy process. A composite suitability map created revealed that 7.5% of the watershed is of a very high suitable class, while 17.5% of the watershed is of a very low suitable class. To select an ideal location, a semi-automatic approach was developed to identify narrow valleys by intersecting contour with stream order and the suitability layer. Eighteen (18) potential dam sites were identified after a query operation was done. The developed method was validated using field data which were correlated with the model output using t-Test; paired two samples for the mean. A strong Pearson correlation of 0.71 between the field data and the semi-automatic approach was observed. The approach offers good prospects for dam site selection. Based on a field survey, the potential dam sites are feasible economically and technically for SHP dam construction that will provide cheap renewable energy to millions of inhabitants in the watershed.
Influence of microbiological diagnosis on the clinical course of spondylodiscitis
Authors: Stangenberg Martin , Mende Klaus Christian , Mohme Malte , Krätzig Theresa , Viezens Lennart , Both Anna , Rohde Holger , Dreimann Marc 
Published: July 2021

Abstract
Purpose
This study sought to recognize differences in clinical disease manifestations of spondylodiscitis depending on the causative bacterial species.

Methods
We performed an evaluation of all spondylodiscitis cases in our clinic from 2013–2018. 211 patients were included, in whom a causative bacterial pathogen was identified in 80.6% (170/211). We collected the following data; disease complications, comorbidities, laboratory parameters, abscess occurrence, localization of the infection (cervical, thoracic, lumbar, disseminated), length of hospital stay and 30-day mortality rates depending on the causative bacterial species. Differences between bacterial detection in blood culture and intraoperative samples were also recorded.

Results
The detection rate of bacterial pathogens through intraoperative sampling was 66.3% and could be increased by the results of the blood cultures to a total of 80.6% (n = 170/211). S. aureus was the most frequently detected pathogen in blood culture and intraoperative specimens and and was isolated in a higher percentage cervically than in other locations of the spine. Bacteremic S. aureus infections were associated with an increased mortality (31.4% vs. overall mortality of 13.7%, p = 0.001), more frequently developing complications, such as shock, pneumonia, and myocardial infarction. Comorbidities, abscesses, length of stay, sex, and laboratory parameters all showed no differences depending on the bacterial species.

Conclusion
Blood culture significantly improved the diagnostic yield, thus underscoring the need for a structured diagnostic approach. MSSA spondylodiscitis was associated with increased mortality and a higher incidence of complications.
Avoid, Trap, and Mitigate: Development of an Evidence-Based Crisis Management Framework in Surgery
Authors: Gogalniceanu Petrut , Karydis Nikolaos , Loukopoulos Ioannis , Kessaris Nicos , Sevdalis Nick , Mamode Nizam 
Published: July 2021

BACKGROUND:
Increasingly, surgeons are adopting broader roles in emergency response, on both clinical and executive levels. These have highlighted the need to develop healthcare-specific crisis management systems. Cross-professional research between safety-critical industries is a valuable method for learning crisis control. Commercial aviation, in particular, has been used to drive innovation in surgical safety. This study aimed to identify, adapt, and operationalize a surgical crisis management framework based on current practice in commercial aviation.

STUDY DESIGN:
A multimethod qualitative study interrogated safety experts in commercial aviation and healthcare. Stage I used immersive observational fieldwork in commercial aviation practice. Stage II performed semi-structured interviews with senior airline pilots. “Snowball” sampling targeted professional networks, recruiting 17 pilots from 4 airlines. Thematic analysis was used to derive a model of crisis management. Stage III undertook 3 focus groups with 5 pilots and 5 healthcare safety specialists. Expert consensus methods were used to adapt the model to clinical practice.

RESULTS:
Interview data provided 2,698 verbatim quotes on crisis management from aviation experts with a combined flying experience of 188,000 hours. Aviation crisis management was structured in 3 phases: avoid, trap, and mitigate. Adapted to clinical practice, these translated to crisis preparedness, recovery, and containment interventions. Additionally, the study identified 7 types of implementation tools and 9 crisis management skills that could be used to operationalize this framework in surgical practice.

CONCLUSIONS:
Surgical crisis management can follow the avoid, trap, and mitigate framework used in commercial aviation. Implementation relies on the combined use of crisis skills and performance tools. Crisis management should be delivered as part of a systems-based approach that relies on well-integrated failure management models. Simulation and in-situ validation of this framework is needed.
Outbreak of Burkholderia contaminans endophthalmitis traced to a clinic ventilation system
Authors: Spilker Theodore , Kratholm Jens , Depoorter Eliza , Vandamme Peter , LiPuma John J. 
Published: July 2021

AbstractWe describe the follow-up investigation of an outbreak of endophthalmitis due to Burkholderia contaminans following cataract surgery in a single clinic. Whole-genome sequence analysis of bacteria recovered from affected patients and the clinic identified the clinic’s ventilation system as the source of infection.
Modelling the Vadret da Tschierva, Switzerland: calibration with the historical length record and future response to climate change
Authors: Oerlemans Johannes , Keller Felix 
Published: July 2021

AbstractThe Vadret da Tschierva (Vd Tschierva) is a 4 km long glacier in the Swiss Alps spanning an altitude range of 2400–4049 m a.s.l. Length observations since 1855 show steady retreat interrupted by a period of advance from 1965 until 1985. The total retreat is ~2200 m (period 1855–2018). We have studied the Vd Tschierva with a flowline model, combined with ‘buckets’ that represent steep hanging glaciers and ice-free rock faces delivering mass to the main stream. The model is calibrated by a control method, in which an ELA history is objectively determined by finding the best match between observed and simulated glacier length. There is a modest correlation between the reconstructed ELA and an ELA record based on meteorological observations at Segl-Maria (only 8 km away from the glacier). It is difficult to reproduce the observed length record when the glacier model is driven by climate model output (Coupled Model Intercomparison Project 5). We have calculated the future evolution of the Vd Tschierva for different rates of ELA rise. For a constant rise of 4 ${\rm m\;}{\rm a}^{ \hbox{-} 1}$, we predict that the glacier length will change from the current 3.2 km to ~1.7 km in the year 2100.
ON HIGHER FROBENIUS–SCHUR INDICATORS
Authors: LIU YANJUN , WILLEMS WOLFGANG 
Published: July 2021

AbstractSimilarly to the Frobenius–Schur indicator of irreducible characters, we consider higher Frobenius–Schur indicators$\nu _{p^n}(\chi ) = |G|^{-1} \sum _{g \in G} \chi (g^{p^n})$for primespand$n \in \mathbb {N}$, whereGis a finite group and$\chi $is a generalised character ofG. These invariants give answers to interesting questions in representation theory. In particular, we give several characterisations of groups via higher Frobenius–Schur indicators.
Ketogenic diets, physical activity and body composition: a review
Authors: Ashtary-Larky Damoon , Bagheri Reza , Bavi Hoda , Baker Julien S. , Moro Tatiana , Mancin Laura , Paoli Antonio 
Published: July 2021

AbstractObesity remains a serious relevant public health concern throughout the world despite related countermeasures being well understood (i.e. mainly physical activity and an adjusted diet). Among different nutritional approaches, there is a growing interest in ketogenic diets (KD) to manipulate body mass (BM) and to enhance fat mass loss. KD reduce the daily amount of carbohydrate intake drastically. This results in increased fatty acid utilisation, leading to an increase in blood ketone bodies (acetoacetate, 3-β-hydroxybutyrate and acetone) and therefore metabolic ketosis. For many years, nutritional intervention studies have focused on reducing dietary fat with little or conflicting positive results over the long term. Moreover, current nutritional guidelines for athletes propose carbohydrate-based diets to augment muscular adaptations. This review discusses the physiological basis of KD and their effects on BM reduction and body composition improvements in sedentary individuals combined with different types of exercise (resistance training or endurance training) in individuals with obesity and athletes. Ultimately, we discuss the strengths and the weaknesses of these nutritional interventions together with precautionary measures that should be observed in both individuals with obesity and athletic populations. A literature search from 1921 to April 2021 using Medline, Google Scholar, PubMed, Web of Science, Scopus and Sportdiscus Databases was used to identify relevant studies. In summary, based on the current evidence, KD are an efficient method to reduce BM and body fat in both individuals with obesity and athletes. However, these positive impacts are mainly because of the appetite suppressive effects of KD, which can decrease daily energy intake. Therefore, KD do not have any superior benefits to non-KD in BM and body fat loss in individuals with obesity and athletic populations in an isoenergetic situation. In sedentary individuals with obesity, it seems that fat-free mass (FFM) changes appear to be as great, if not greater, than decreases following a low-fat diet. In terms of lean mass, it seems that following a KD can cause FFM loss in resistance-trained individuals. In contrast, the FFM-preserving effects of KD are more efficient in endurance-trained compared with resistance-trained individuals.
Seroprevalence of Strongyloides stercoralis among patients with leptospirosis in northern Iran: a descriptive cross-sectional study
Authors: Varzegar P. , Bayani M. , Kalantari N. , Nasiri-kenari M. , Amini Navaie B. , Mollalo A. , Rostami A. 
Published: July 2021

Abstract
Strongyloidiasis and leptospirosis are neglected tropical diseases that have affected many countries across the world. In this study, we evaluated the seroprevalence of Strongyloides stercoralis among patients with leptospirosis in northern Iran. We evaluated 156 laboratory- or clinically confirmed leptospirosis cases. The overall seroprevalence of S. stercoralis was 32.0% (95% confidence interval (CI): 27.4–36.5%, 50/156). Seropositivity was significantly associated with agricultural activities (odds ratio (OR): 2.84, 95% CI: 1.0–8.77) and gastrointestinal disorders (OR: 2.4, 95% CI: 1.1–4.9). Laboratory findings indicated that seropositivity of S. stercoralis was significantly associated with decreased levels of platelet and elevated levels of creatinine, alanine aminotransferase and aspartate aminotransferase (P < 0.05). Our findings suggested a higher exposure to S. stercoralis larvae among patients with leptospirosis. The public health and medical communities may benefit from this research through preventive measures to improve farmers’ knowledge and awareness regarding strongyloidiasis and leptospirosis and the associated risk factors.
A daily diary study into the effects on mental health of COVID-19 pandemic-related behaviors
Authors: Shaw Philip , Blizzard Sam , Shastri Gauri , Kundzicz Paul , Curtis Brenda , Ungar Lyle , Koehly Laura 
Published: July 2021

AbstractBackgroundRecommendations for promoting mental health during the COVID-19 pandemic include maintaining social contact, through virtual rather than physical contact, moderating substance/alcohol use, and limiting news and media exposure. We seek to understand if these pandemic-related behaviors impact subsequent mental health.MethodsDaily online survey data were collected on adults during May/June 2020. Measures were of daily physical and virtual (online) contact with others; substance and media use; and indices of psychological striving, struggling and COVID-related worry. Using random-intercept cross-lagged panel analysis, dynamic within-person cross-lagged effects were separated from more static individual differences.ResultsIn total, 1148 participants completed daily surveys [657 (57.2%) females, 484 (42.1%) males; mean age 40.6 (s.d.12.4) years]. Daily increases in news consumed increased COVID-related worrying the next day [cross-lagged estimate = 0.034 (95% CI 0.018–0.049), FDR-adjustedp= 0.00005] andvice versa[0.03 (0.012–0.048), FDR-adjustedp= 0.0017]. Increased media consumption also exacerbated subsequent psychological struggling [0.064 (0.03–0.098), FDR-adjustedp= 0.0005]. There were no significant cross-lagged effects of daily changes in social distancing or virtual contact on later mental health.ConclusionsWe delineate a cycle wherein a daily increase in media consumption results in a subsequent increase in COVID-related worries, which in turn increases daily media consumption. Moreover, the adverse impact of news extended to broader measures of psychological struggling. A similar dynamic did not unfold between the daily amount of physical or virtual contact and subsequent mental health. Findings are consistent with current recommendations to moderate news and media consumption in order to promote mental health.
Do employment promotion policies affect employment or job transfer among older adults? Evidence from Japan
Authors: Jiang Mingyu 
Published: July 2021

AbstractIn most rapidly ageing industrialised countries, ageing problems have become an important social issue. In Japan, owing to the rapidly ageing population, the government has been intervening in both the demand side and supply side of labour to increase employment of older adults. This study examines labour supply responses to the increasing pension eligibility age and labour demand responses to company expansion and the abolition of the employee selection mechanism. This study is based on Japanese longitudinal survey data (Keio Household Panel Survey) from 2008 to 2018. Since employment law revisions and social security revisions are inextricably linked, one way to examine the effect of revisions to both simultaneously is to investigate them by cohort. The difference-in-difference model was used to compare revision-affected cohorts born between April 1953 and January 1956 and unaffected cohorts born between April 1949 and March 1953. It was found that the revisions had almost no impact on the employment of older adults and their receipt of pensions. However, they did have significant positive effects on job transfers and resignations. Hence, although the system was modified, it also gave companies the option of placing older adults in associated companies and of retaining some routes for older adults to retire, much as before the revisions.
Changes in Multiple Birth Rates and Parental Demographic Factors in South Korea During the Last Four Decades: 1981–2019
Authors: Hur Yoon-Mi 
Published: July 2021

AbstractOver the previous decades, twinning rates worldwide have increased remarkably. This study aimed to describe changes in multiple birth rates and related demographic characteristics, such as maternal age and the level of education of parents in South Korea from 1981 to 2019. This study analyzed birth data obtained from the Korean Statistical Information Service. From 1981 to 2019, the total twinning rate increased from 5 to 22.5 pairs per 1000 births. This rapid increase was due to an increase in dizygotic twin births, which mainly occurred in mothers aged between 30 and 39 years. The average maternal age of multiples increased from 26.06 years in 1981 to 33.98 years in 2019, suggesting that a delay in childbearing contributed to the increase in the twinning rate. The percentage of mothers of multiples who completed a college or higher degree (CHD) increased by 1000% from 1981 to 2019, indicating that a sharp increase in the level of education of females in part explains the delay in childbearing. The percentages of individuals who completed a CHD were higher among parents of multiples than among those of singletons in recent years when public funding arrangements for fertility treatments were available. This result suggested that completion of higher education may be associated with increased use of assisted reproductive technology (ART) independent of the financial status of couples. Taken together, the analysis suggested that increased maternal age, ART and the increased number of females who completed CHD may be responsible for the remarkable increase in the rates of multiple births in South Korea in the last four decades.
Evaluation of panicle removal methods and crop topping applications as supplemental tools for wild oat (Avena fatua) management
Authors: Tidemann Breanne D. , Harker K. Neil , Shirtliffe Steve J. , Willenborg Christian J. , Johnson Eric N. , Sroka Elizabeth , Zuidhof Jennifer , Duddu Hema 
Published: July 2021

AbstractIncreased frequency and occurrence of herbicide-resistant biotypes heightens the need for alternative wild oat management strategies. This study aimed to exploit the height differential between wild oat and crops by targeting wild oat between panicle emergence and seed shed timing. Two field studies were conducted either in Lacombe, AB, or Lacombe, AB and Saskatoon, SK, from 2015 to 2017. In the first study, we compared panicle removal methods: hand clipping, use of a hedge trimmer, and a selective herbicide crop topping application to a weedy check and an industry standard in-crop herbicide application in wheat. These treatments were tested early (at panicle emergence), late (at initiation of seed shed), or in combination at one location over 3 yr. In the second study, we investigated optimal timing of panicle removal via a hedge trimmer with weekly removals in comparison to a weedy check in wheat and lentil. This study was conducted at two locations, Lacombe, AB, and Saskatoon, SK, over 3 yr. Among all the tested methods, the early crop topping treatment consistently had the largest impact on wild oat density, dockage, seedbank, and subsequent year crop yield. The early (at panicle emergence) or combination of early and late (at initiation of seed shed) treatments tended to reduce wild oat populations the following season the most compared to the late treatments. Subsequent wild oat populations were not influenced by panicle removal timing, but only by crop and location interactions. Panicle removal timing did significantly affect wild oat dockage in the year of treatment, but no consistent optimal timing could be identified. However, the two studies together highlight additional questions to be investigated, as well as the opportunity to manage wild oat seedbank inputs at the panicle emergence stage of the wild oat lifecycle.
The zinc finger transcription factor, KLF2, protects against COVID-19 associated endothelial dysfunction
Authors: Xu Suowen , Liu Yujie , Ding Yu , Luo Sihui , Zheng Xueying , Wu Xiumei , Liu Zhenghong , Ilyas Iqra , Chen Suyu , Han Shuxin , Little Peter J. , Jain Mukesh K. , Weng Jianping 
Published: July 2021

AbstractCoronavirus disease 2019 (COVID-19) is regarded as an endothelial disease (endothelialitis) with its patho-mechanism being incompletely understood. Emerging evidence has demonstrated that endothelial dysfunction precipitates COVID-19 and its accompanying multi-organ injuries. Thus, pharmacotherapies targeting endothelial dysfunction have potential to ameliorate COVID-19 and its cardiovascular complications. The objective of the present study is to evaluate whether kruppel-like factor 2 (KLF2), a master regulator of vascular homeostasis, represents a therapeutic target for COVID-19-induced endothelial dysfunction. Here, we demonstrate that the expression of KLF2 was reduced and monocyte adhesion was increased in endothelial cells treated with COVID-19 patient serum due to elevated levels of pro-adhesive molecules, ICAM1 and VCAM1. IL-1β and TNF-α, two cytokines elevated in cytokine release syndrome in COVID-19 patients, decreased KLF2 gene expression. Pharmacologic (atorvastatin and tannic acid) and genetic (adenoviral overexpression) approaches to augment KLF2 levels attenuated COVID-19-serum-induced increase in endothelial inflammation and monocyte adhesion. Next-generation RNA-sequencing data showed that atorvastatin treatment leads to a cardiovascular protective transcriptome associated with improved endothelial function (vasodilation, anti-inflammation, antioxidant status, anti-thrombosis/-coagulation, anti-fibrosis, and reduced angiogenesis). Finally, knockdown of KLF2 partially reversed the ameliorative effect of atorvastatin on COVID-19-serum-induced endothelial inflammation and monocyte adhesion. Collectively, the present study implicates loss of KLF2 as an important molecular event in the development of COVID-19-induced vascular disease and suggests that efforts to augment KLF2 levels may be therapeutically beneficial.