bluuebunny/crossref_metadata_2025_split huggingface dataset:
Acute L1 chalkstick fracture post fall in a patient with known ankylosing spondylitis and previous instrumentation and fusion of T8-L1
Authors: Choy Yu Bin Ariel , Chan Daniel Nim Cho , Chen Hao Bin , Yilun Huang 
Published: November 2021

Background:
Patients with ankylosing spondylitis (AS) are especially prone to sustaining spinal fractures. A 72-year-old male with AS had a previous T10/11 chalkstick fracture requiring a T8-L1 fusion 1 year ago. He subsequently presented with a newly diagnosed acute chalkstick fracture of L1 which was treated without surgery.

Case Description:
A 72-year-old male with AS and a T10/11 chalkstick fracture had undergone a T8-L1 thoracolumbar fusion 1 year ago. He newly presented after a fall from his bed with a new acute L1 chalkstick fracture that was successfully managed nonsurgically.

Conclusion:
Patients with AS are at high risk for spinal fractures. Here, elderly male, following an original T10/11 chalkstick fracture and a T8-L1 fusion 1 year ago, presented with a new acute L1 chalkstick fracture managed without surgery.
Non-anticoagulant and other properties of low molecular weight heparins
Authors: Ройтман Е.В. , Печенников В.М. 
Published: November 2021

Низкомолекулярные гепарины (НМГ) являются уникальными препаратами: образуя одну группу, объединенную антитромботическим действием, каждое МНН (международное непатентованное наименование) дополнительно предоставляет свой спектр плейотропного (неантитромботического) действия со своим профилем клинической эффективности. Из-за различий в структуре этих препаратов не следует переносить результаты, полученные с одним НМГ, на другой. Однако различия между ними не делают какой-то один НМГ лучше или хуже другого. Напротив, они позволяют выбрать если не оптимальный, то наиболее подходящий препарат для конкретного пациента. При выборе НМГ для конкретного пациента необходимо строго руководствоваться инструкцией по медицинскому применению и тщательным подбором индивидуальной дозы препарата, исходя из массы тела пациента, степени тяжести заболевания, сопутствующей патологии, а также принимая во внимание ряд других факторов.
Low molecular weight heparins (LMWHs) make one pharmacological group due to their antithrombotic action, but each of their international nonproprietary names provides additionally its own spectrum of pleiotropic (non-antithrombotic) actions with a specific profile for clinical efficacy. Due to the differences in the structure of these medications the results obtained with one LMWH should not be transferred to another. However, differences between LMWHs do not make one better or worse than the other. On the contrary, it allows you to choose if not optimal then the most suitable LMWH for the patient taking into account a number of influencing factors as well.
Hematogenous thrombophilia as an additional risk factor for cerebral circulation disorders
Authors: Куртов И.В. , Кривова С.П. , Хайретдинов Р.К. , Давыдкин И.Л. 
Published: November 2021

Введение. Гематогенная тромбофилия служит дополнительным фактором риска нарушений мозгового кровообращения (НМК). Цель исследования: изучить влияние повышенного уровня фактора VIII и нарушений в системе фибринолиза на НМК у пациентов с сочетанной патологией системы свертывания крови. Материалы и методы. Обследовано 20 пациентов с перенесенными ишемическими инсультами в возрасте от 36 до 56 лет. Определяли показатели плазменного, тромбоцитарного звеньев гемостаза, системы фибринолиза, а также генетические полиморфизмы системы гемостаза. Результаты. У всех пациентов выявлены различные сочетания генетических полиморфизмов, связанных с изменениями антикоагулянтного звена гемостаза, а также дефекты системы фибринолиза и коагуляционного звена гемостаза, что является дополнительным фактором риска НМК. Заключение. У пациентов молодого и среднего возраста, перенесших острое НМК по ишемическому типу, необходимо исследование системы свертывания крови, включающее определение содержания фактора VIII в крови, показателей системы фибринолиза и уровня гомоцистеина.
Background. Hematogenous thrombophilia is an additional risk factor for cerebral circulatory disorders (ССD). Objectives: to study the impact of increased factor VIII level and disturbances of fibrinolysis system on ССD in patients with combined pathology of blood coagulation. Patients/Methods. We examined 20 patients with ischemic strokes aged from 36 to 56 years. The parameters of plasma hemostasis, platelet function, fibrinolysis system, as well as the genetic polymorphisms of hemostasis system were determined. Results. All patients had different combinations of genetic polymorphisms associated with anticoagulant hemostasis changes, as well as defects in fibrinolysis system and coagulation hemostasis that is an additional risk factor for ischemic stroke. Conclusions. In young and middle-aged patients with history of acute ischemic ССD, it is necessary to study blood coagulation, including the determination of blood factor VIII level, fibrinolysis system parameters and homocysteine content.
Experience in a comprehensive pre-test risk assessment of thromboembolic complications in surgical patients with a high risk of congenital thrombophilia.
Authors: Каражанова Л.К. , Исаханова С.А. 
Published: November 2021

Введение. Каждый год около трети летальных исходов от венозных тромбоэмболических осложнений (ВТЭО) в мире приходится на долю пациентов, перенесших хирургические вмешательства. Традиционные подходы в оценке рисков не всегда подходят пациентам хирургического профиля в связи с широкой разрозненностью возрастных групп, наличием пациентов с различными тромбофилическими состояниями, высокими рисками предстоящих вмешательств и низкой настороженностью персонала. Выходом из этой ситуации является поиск лучших инструментов для проведения предтестовой диагностики. Цель исследования: анализ результатов комплексной предтестовой оценки риска развития ВТЭО у пациентов хирургического профиля с высоким риском наличия врожденных тромбофилий. Материалы и методы. Обследовано 35 пациентов с одним из проявлений ВТЭО (основная группа) и 55 пациентов, указавшие на наличие ВТЭО у себя в прошлом или у родственников первой кровной линии в возрасте до 50 лет (контрольная группа). Проведено тестирование по шкалам Geneva, Wells, Caprini с последующим анализом. Для выявления нарушений в системе протеина С применяли «Парус-тест». Результаты. Предтестовая оценка с применением шкалы Caprini и нормализованного отношения (НО) «Парус-теста» показала высокий риск развития ВТЭО у пациентов обеих групп. Заключение. Тестирование с помощью шкалы Caprini и НО «Парус-теста» показало хорошие результаты для оценки рисков развития ВТЭО и качественного подбора метода профилактики ВТЭО у пациентов хирургического профиля.
Background. Every year, about a third of deaths from venous thromboembolic complications (VTEC) in the world occur among surgical patients. Traditional risk assessment is not always suitable for surgical patients due to the wide disparity of age groups, the presence of patients with various thrombophilic conditions, high risks of forthcoming interventions, and low medical staff alertness. The solution is to find the best tools for pre-test diagnostics. Objectives: to analyze the results of a comprehensive pre-test assessment of VTEC risk in surgical patients with a high risk of congenital thrombophilia. Patients/Methods. We examined 35 patients with one of VTEC manifestations (main group) and 55 patients who had a history of VTEC or VTEC episode in first blood line relatives under the age of 50 (control group). Testing was carried out according to Geneva, Wells, and Caprini scales with subsequent analysis. Parus-test was used to detect the disturbances in protein C system. Results. The pre-test assessment using the Caprini scale and the normalized ratio (NR) of Parus-test showed a high risk of VTEC in patients of both groups. Conclusions. Testing with the Caprini scale and NR of Parus-test showed good results for assessment of VTEC risks and for a qualitative selection of VTEC prevention method in surgical patients.
Aspectos clínicos e histopatológicos do Lúpus Eritematoso Discoide canino: relato de caso
Authors: Leal Stphanie Larissa Ramos de Santana , Silva Joelma Gomes da , Tertulino Moisés Dantas , Barreto Giovana Meireles Fixina , Noronha Jéssyka Araújo , Rodrigues Lívia Maria Nascimento , Medeiros Natália Cristina de 
Published: November 2021

O Lúpus Eritematoso Discoide (LED) é uma dermatopatia autoimune. Sua etiologia ainda não está completamente elucidada, porém é pressuposto que se trata de uma doença multifatorial. Objetivou-se, neste trabalho, relatar um caso de LED em um cão sem raça definida, idoso, atendido no Hospital Veterinário Jerônimo Dix-Huit Rosado Maia, Mossoró – RN. O paciente apresentava lesão em ponte nasal com presença de ulcerações e crostas de evolução gradativa em um período de dois meses. Foram realizados exame histopatológico e diagnóstico diferencial para leishmaniose visceral canina por meio de ELISA e RIFI, confirmando LED. O protocolo terapêutico incluiu medicação tópica à base de hidrocortisona (1%), vitamina E (0,5%) e fator de proteção 45 a cada 12 horas por 20 dias; a terapia sistêmica se deu através da administração de prednisolona (1mg/kg a cada 24 horas, durante 20 dias; 0,75mg/kg, a cada 24 horas, durante 20 dias; 0,5mg/kg, a cada 24 horas, durante 20 dias, seguido de 0,25mg/kg, durante 20 dias; até retirada completa do medicamento), protetor hepático (2 comprimidos, a cada 24 horas durante 30 dias), além de precauções quanto à exposição solar. Após quatro meses, o paciente apresentou remissão completa, sem presença de recidiva mesmo após a suspensão do tratamento, mantendo-se sem recidivas após 8 meses do término do protocolo terapêutico. Recomendou-se usar protetor solar fator 45 por toda a vida do animal. Deste modo, concluiu-se que o protocolo estabelecido é eficaz para o tratamento de LED, salientando a importância da realização de exames complementares para obtenção do diagnóstico definitivo.
APLIKASI KONTROL PID PADA OUTLET GAS UNIT SLUG CATCHER METODE INTERFACING HYSYS-MATLAB
Authors: Nasrunna Nasrul Dara Sabhira , ZA Nasrul , Muhammad Muhammad 
Published: November 2021

Penelitian Kontrol Proportional – Integral (PI) adalah kontroller yang berfungsi menentukan presisi suatu sistem instrumentasi dengan karakteristik adanya umpan balik pada sistem tersebut (Feed back). Slug Catcher adalah sebuah alat pemisah digunakan untuk memisahkan lumpur, lendir, minyak, air dan gas yang berasal dari Wellpad. Metodologi penelitian ini adalah membuat model steady state Slug Catcher, lalu mengubah model steady state menjadi model dynamic, lalu membuat model kontrol PI, setelah itu melakukan tuning terhadap kontrol PI dan melakukan pengujian terhadap kontrol PI, dengan cara memberi gangguan pada set point. Penelitian ini bertujuan untuk mendapatkan waktu respon tercepat terhadap gangguan tekananan serta mendapatkan variable Kc dan Ti terbaik. Hasil dari penelitian pengaplikasian sistem kontrol PI didapatkan waktu tercepat yaitu 0.1 menit dengan nilai Kc= 1, dan Ti= 0.01. Pada suhu 85.31oC dengan tekanan 4238 kPa dengan laju alir 339.62 MMSCFD. Sedangkan waktu terlama pada hasil pengujian kontrol PID dengan mengubah tekanan menjadi 4270 kPa , yaitu 2.8 menit dengan nilai Kc= 1.07, dan nilai Ti= 0.04.
EFEKTIVITAS KARBON AKTIF KULIT SINGKONG (Manihot Esculenta Crantz) TERHADAP ADSORPSI ION LOGAM Fe2+ DENGAN AKTIVATOR NaOH
Authors: Masrullita Masrullita , Wijaya Yogi Ardhika , Sylvia Novi , Safriwardy Ferri 
Published: November 2021

Salah satu pencemar yang berbahaya dalam limbah buangan industri yaitu logam berat besi (Fe2+). Banyak teknik pengolahan yang dilakukan untuk mwnurunkan kadar logam berat besi. Salah satunya diantaranya adalah dengan teknik adsorbs. Adsorpsi sering digunakan karena prosesnya yang sederhana dan efektif untuk mengurangi kadar logam berat. Penelitian ini bertujuan untuk menganalisis efektifitas karbon aktif kulit singkong sebagai adsorben pada penyerapan logam besi (Fe2+), mengkaji pengaruh waktu kontak dan variasi konsentrasi aktivator terhadap daya serap besi (Fe2+) serta mekanisme penyerapan melalui metode pendekatan isotherm adsorpsi Freundlich dan Langmuir. Penelitian ini dilakukan dengan suhu karbonasi 300 ºC selama 2 jam dengan variasi konsentrasi aktivator 10%, 20%, 25%, dan 30% serta memvariasikan waktu kontak selama 30, 60, 90, dan 120 menit. Hasil yang diperoleh adalah, % efisiensi adsorpsi maksimum yaitu 94,07% serta kapasitas adsorpsi maksimum yaitu 470,35 mg/g pada konsentrasi aktivator 30% dan waktu kontak 120 menit. Mekanisme adsorpsi yang terjadi mendekati persamaan isotherm Langmuir dengan nilai R2 = 0,9999, diduga proses penyerapan terjadi secara kimisorpsi monolayer. Dari hasil yang diperoleh dapat disimpulkan bahwa semakin lama waktu kontak dan semakin tinggi konsentrasi aktivator maka semakin tinggi kapasitas adsorpsi dan % efisiensi adsorpsi Fe2+ yang diperoleh.
Inovasi Desain Untuk Meningkatkan Kualitas Produk Batik
Authors: Astawinetu Erwin Dyah , Wijayanti Yulyar Kartika , Hidayati Cholis 
Published: November 2021

Mitra program ini adalah UMKM Batik yang memiliki beberapa masalah ketika kami berkoordinasi sehingga kami menawarkan kepada mereka untuk mengatasi masalah yang mereka hadapi. Tujuan dari program yaitu pendampingan manajemen usaha yang diterapkan dalam bisnis. Beberapa solusi akan dilakukan dalam program untuk kelompok Batik dalam manajemen usaha, pemasaran dan kualitas. Untuk meningkatkan kemampuan mengelola usaha batik diadakan Pelatihan dan Pendampingan Manajemen Usaha. Untuk meningkatkan pemasaran kami akan memberikan pelatihan dan pendampingan inovasi desain dan strategi pemasaran bagi anggota kelompok batik agar memiliki kemampuan dalam memasarkan produknya dengan harapan akan meningkatkan penjualan batik mereka. Kegiatan ini dilakukan dan peningkatan dalam mengelola dan memasarkan produk bagi pengunjung yang berwisata di Desa. Dengan adanya berbagai desain batik baru serta bahan kain yang baik meningkatkan produktivitas mereka sekitar 50% dibandingkan sebelum program. Peningkatan penjualan mempengaruhi produk lokal lain seperti susu, kopi dan makanan desa. Pelatihan manajemen kualitas, desain dan inovasi berhasil meningkatkan penjualan produk. Our partners are Batik SMEs who have some problems when we coordinate so we offer them to help solve their problems. The aim of this program in business management assistance that is applied to their business. Solutions will be carried out in the program for the groups in management, marketing, and quality. Improving the Business, management Training is held. We will provide training and assistance on design innovations for batik group members so that they can sell and increase sales. The result was an extraordinary increase in managing and marketing products for visitors who traveled in the village. The existence of various new batik designs and good fabrics has increased their productivity by about 50% compared to before the program. This increase in sales affects other local products such as milk, coffee, and village food. Providing management training, designs and innovations that will increase the sales.
Relaksasi Otot Progresif Terhadap Penurunan Tingkat Stres Akademik
Authors: Rahmawati Farida Nur 
Published: November 2021

Pandemi covid-19 menimbulkan berbagai permasalahan di masyarakat, salah satunya adalah stres akademik yang dirasakan oleh mahasiswa. Stres akademik yang dirasakan terus menerus oleh mahasiswa akan berdampak pada hasil belajar mahasiswa. Berdasarkan permasalahan tersebut maka diadakan kegiatan pengabdian masyarakat berupa pelatihan secara daring mengenai relaksasi otot progresif untuk menurunkan stres akademik mahasiswa. Tujuan dari kegiatan pengabdian masyarakat ini adalah agar masyarakat lebih khususnya mahasiswa mampu menambah pengetahuan dan keterampilan mengenai pengaplikasian relaksasi otot progresif agar dapat menurunkan stres akademik. Hasil analisis data ditemukan bahwa nilai sig (p) = 0.000 (p<0.05) hal ini bermakna bahwa terdapat perbedaan antara skor sebelum diberikan pelatihan (pre-test) dengan sesudah diberikan pelatihan (pos-test), penjelasan tersebut terlihat dari adanya penurunan stres akademik yang dirasakan oleh peserta setelah mengikuti pelatihan relaksasi otot progresif. The Covid-19 pandemic has caused various problems in society, one of which is academic stress felt by students. Academic stress that is felt continuously by students will have an impact on student learning outcomes. Based on these problems, community service activities were held in the form of online training on progressive muscle relaxation to reduce student academic stress. The purpose of this community service activity is for the community, especially students, to be able to increase their knowledge and skills regarding the application of progressive muscle relaxation in order to reduce academic stress. The results of data analysis found that the value of sig (p) = 0.000 (p<0.05) this means that there is a difference between the scores before being given training (pre-test) and after being given training (post-test), the explanation can be seen from the decrease in stress the academic experience felt by participants after participating in progressive muscle relaxation training.
Influence of Geometric Features Associativity of CAD Class Models on the Process of Their Updating – Comparative Analysis
Authors: Świaczny Grzegorz 
Published: November 2021

This article deals with the topic of one of the most important features of modern CAx class systems – associativity. The term refers to the ability to form relations (links) between two or more objects (in terms of their selected features), and with the consequence creating an associative (linked) three-dimensional model. The author pays special attention to the very process of creating relations between objects, as it has a key impact on the structural stability of CAD class models, and thus on their susceptibility to possible modifications. To show that not all associativity brings a positive effect, the author presents two examples of its implementation. In order to emphasize the influence of the method of linking individual elements, both examples are based on the same 3D model – a thin-walled part with a positioning pin. That means the geometric form of the default part is the same, whereas only relations of the individual objects of the 3D model change. In the first scenario, correctly defined relations between objects make that the positioning pin offset does not affect the initial design conditions. The second scenario shows an incorrect implementation of associativity, as a result of which the same operation of positioning pin offset gives non-compliance with the initial design conditions and with the consequence an undesirable change in its geometry.
The article is an attempt to draw attention to the fact that the associative structure of 3D models is not always equal to the optimal solution. Only the well-thought-out nature of associativity allows to use all its advantages.
Pengembangan Buku Ajar Metode Numerik Berbasis Pembelajaran Kolaboratif
Authors: Purwati Ni Kadek Rini , Erawati Ni Ketut 
Published: November 2021

AbstrakBuku ajar metode numerik haruslah memuat gambaran lengkap materi dan lebih menekankan pada implementasi metode, sehingga dapat menciptakan pembelajaran yang aktif dan interaktif. Penerapan pembelajaran kolaboratif yang diintegrasikan melalui buku ajar metode numerik akan menciptakan suasana pembelajaran yang mendorong mahasiswa untuk saling berinteraksi, bekerjasama, berbagi peran, tugas, dan tanggung jawab dalam menyelesaikan tugas atau masalah. Tujuan penelitian ini adalah untuk mengembangkan buku ajar metode numerik berbasis pembelajaran kolaboratif yang valid, praktis, dan efektif. Penelitian ini merupakan penelitian pengembangan Model Plomp yang terdiri dari tiga fase, yakni fase penelitian awal, fase membuat prototipe, dan fase penilaian dimana pada fase ini dilakukan uji validitas berdasarkan lembar validasi, kepraktisan berdasarkan angket respon dan keefektifan berdasarkan lembar observasi dan tes. Subjek penelitian adalah mahasiswa program studi pendidikan matematika IKIP PGRI Bali. Hasil yang diperoleh adalah buku yang dikembangkan layak digunakan, kepraktisan tergolong baik dan buku ajar metode numerik efektif digunakan dalam perkuliahan.Kata Kunci: Buku Ajar, Pembelajaran Kolaboratif, Penelitian Pengembangan Development of Numerical Methods Textbook Based on Collaborative LearningAbstractNumerical method textbooks must contain a complete description of the material and put more emphasis on the implementation of the method, to create active and interactive learning. The application of collaborative learning that is integrated through numerical methods textbooks will create a learning atmosphere that encourages students to interact, collaborate, share roles, assignments, and responsibilities in solving assignments or problems. The purpose of this research is to develop a valid, practical, and effective numerical method textbook based on collaborative learning. This research is research on the development of the Plomp Model which consists of three phases, namely the preliminary research phase, the prototyping phase, and the assessment phase wherein this phase the validity test is carried out based on the validation sheet, the practicality is based on the response questionnaire and the effectiveness is based on the observation sheet and the test. The research subjects were students of the mathematics education study program at the IKIP PGRI Bali. The results obtained are that the book developed is suitable for use, the practicality is good and the numerical method textbook is effectively used in lectures.Keywords: Collaborative Learning, Development Research, Textbook.