bluuebunny/crossref_metadata_2025_split huggingface dataset:
Developing cardiometabolic risk classifiers for youth using handgrip strength, anthropometrics, and demographics: a machine learning approach leveraging National Health and Nutrition Examination Survey Data
Authors: Ajisafe Toyin 
Published: May 2021

Abstract
Background Handgrip strength associates with cardiometabolic (CMB) risk. Health-related physical fitness (HRPF) testing in schools do not explicitly predict CMB disease risk, and commonly engender anxiety, teasing and taunting by peers. Further, school-based screening for hyperinsulinemia using acanthosis nigricans likely misses nascent CMB risk factors like dyslipidemia. This study examined the feasibility of leveraging anthropometrics, demographics, and handgrip strength data to build optimal CMB risk classifiers. Methods The 2011-2014 National Health and Nutrition Examination Survey data from participants aged 12-18 years (n = 402; 205 males) (15.4 ± 1.8 years; 167.4 ± 9.1 cm; 73.2 ± 21.5 kg) who performed bilateral handgrip strength and CMB testing was leveraged. CMB risk was delineated as clustering of three or more risk factors across weight status, mean systolic, mean diastolic, HDL-cholesterol, LDL-cholesterol, total cholesterol, triglycerides, fasting glucose and HOMA-IR. 80% of the balanced dataset was used to train several models (e.g., Decision Tree and K-Nearest Neighbors (KNN)), while 20% was retained for further validation. There were 18 initial features, including age, sex, race, BMI, and combined handgrip strength. SelectKBest, Recurrent Feature Elimination, and Random Forest were deployed to identify the most salient features. Results Resulting models were evaluated using performance metrics such as Area Under the Curve (AUC), recall and precision. The most salient model was a Quadratic Discriminant model involving five features, namely number of people in household, annual household income, number of children 5 years or younger, combined handgrip strength, and waist circumference. When deployed, the model accurately classified 83% and 93% of the positive and negative classes within the test data, respectively (accuracy = 81.7%; AUC = 0.87; Recall = 0.91; Precision = 0.81; F-Measure = 0.92). Conclusions Findings demonstrate demographics, anthropometrics, and handgrip strength can be leveraged (using machine learning techniques) to accurately predict and optimally identify nascent CMB risk in youth while mitigating peer shaming and optimizing student participation in HRPF surveillance protocols in schools. Additional studies are needed to externally validate resulting models and investigate related effects on participation in HRPF testing and CMB risk detection among children and youth.
Osahs Patients With CPAP Complained of Multiple Side Effects: A Meta-analysis of Randomized Trials
Authors: Zhu Chunxue , Liu Qing , Lu Qinyuan , Wang Yicheng , Liu Chengyu , Zhang Xilong , Huang Hanpeng 
Published: May 2021

Abstract
PURPOSE:CPAP (Continuous Positive Airway Pressure) is the "gold standard" treatment for OSAHS (Obstructive Sleep Apnea Hypopnea Syndrome). However, its compliance is only 30% to 70%. Much of the compliance reduction depends on its side effects. This study aimed to perform a meta-analysis of all randomized trials that statistically analyzed the side effects of CPAP.METHODS:The Cochrane, Embase, and Pubmed were searched for relevant studies from inception until September 2019 with the following terms: "OSAHS" and "CPAP" and "side effects". Two reviewers independently extracted data. Meta-analyses on adverse outcomes were calculated with a frequentist approach. Summary sensitivity analysis, risk of bias, and 95%CIs were also obtained. All statistical analyses were performed with R package metaRESULTS:All side effects investigated can be broadly classified into four categories including respiratory tract discomfort, discomfort of the mask, psychological pressure and specific gastrointestinal symptoms. Overall, the random effects meta-analysis revealed that dry symptoms (0.23;95% CI, 0.16-0.32), gas leakage (0.17;95% CI, 0.10-0.27) and sleep disorders (0.14;95% CI, 0.11-0.18) were associated with a higher incidence. Another intergroup analysis showed statistically significant differences in the incidence of dryness and sleep disturbance (0.23;95% CI, 0.16-0.32 vs. 0.14;95% CI, 0.11-0.18, respectively; P =.04)CONCLUSION:Side effects of CPAP are multifaceted and occur in combination with high probability. The impact of specific side effects on compliance needs to be further investigated in clinical data. Meanwhile, medical workers need to consider further the impact of side effects and timely adjust relevant treatment plans or nursing service in the clinic.
Experimental study on infiltration pattern: opportunities for sustainable management in the Northern region of India
Authors: Kumar Vikram , Chaplot Barkha , Omar Padam Jee , S. Shaktibala , Md. Azamathulla H. 
Published: May 2021

Abstract
The infiltration process plays a key role in designing groundwater recharge, irrigation, and drainage systems, and contamination evaluation is controlled by numerous factors, among which soil physical properties and land use & land cover (LULC) are the prime factors. A comprehensive understanding of the spatial water infiltration characteristics over the soil which is site-specific and more complex due to non-uniformity could enhance the agriculture water use efficiency and mitigate water-related issues. The present study deals with the measurement of field infiltration characteristics using a mini disc infiltrometer in all 24 blocks of Gaya districts, Bihar, which covers a wide spectrum of soil types. Results showed that the average cumulative infiltration rate (IR) for the study area varies between 0.38 and 2.20 cm/min with an average rate of 1.16 cm/min. The initial IR among all blocks was found to be high but decreased gradually with each successive reading. Moreover, the land use under forest cumulative IR was more than the cumulative IR for urban and grassland. Eight blocks (33.3%) have an IR more than the average infiltration of the area which is good for storing the water in the aquifer and suggested constructing a recharge structure. Further investigation revealed a small IR in the inundated area, because of the maximum soil water table. The ready-to-use map showing the IR for the district is prepared which could be used by any decision-taking during the high or low rainfall, understanding the hydrological process, development of any reference guide for farmers for increasing the agriculture productivity and soil-water management.
Ease of Doing Business Index: An Analysis of Investors Practical View
Authors: Babatunde Shakirat Adepeju , Ajape Mohammed Kayode , Isa Kabir Dandago , Kuye Owolabi , Omolehinwa Eddy Olajide , Muritala Shefiu Abiodun 
Published: May 2021

Abstract: This study investigates the effect of Ease of Doing Business Index (EDBI) on Return on Investment (ROI). The study employs a cross-sectional survey design covering five years from 2015 to 2019. The sample is 47 registered companies with the Lagos Chamber of Commerce and Industry, which is the most representative of the organised private sector group in Nigeria. The study adopts descriptive and linear regression statistical analysis. Findings show a statistically significant negative effect of Government policy continuity. The government procurement process, Raw materials availability and Quality of workforce show adverse effects. Traffic and transportation management, power supply and Security infrastructure show insignificant effect on ROI. Hence, findings indicate that Government procurement process is inimical to ease of doing business in Nigeria despite the government improvement efforts. Since government efforts are insufficient, the World Bank should incorporate private sector ideals into EDBI to create a synergy a robust EDBI. Keywords: Ease of Doing Business, ease of doing business index, return on investment, investors, World Bank. Ease of Doing Business Index: Sebuah Analisis terhadap Pandangan Praktis InvestorAbstrak: Penelitian ini menginvestigasi pengaruh Ease of Doing Business Index (EDBI) terhadap Return on Investment (ROI). Penelitian ini menggunakan desain survei cross-sectional dari tahun 2015 sampai dengan tahun 2019. Sampel penelitian ini adalah 47 perusahaan yang terdaftar di Lagos Chamber of Commerce and Industry. Penelitian ini menggunakan analisis deskriptif dan statistik regresi linear. Dari berbagai elemen EDBI, temuan dari penelitian ini menunjukkan adanya pengaruh negatif yang signifikan antara keterlanjutan kebijakan pemerintah terhadap ROI. Proses pengadaan pemerintah, ketersediaan bahan mentah, dan kualitas tenaga kerja menunjukkan pengaruh berkebalikan dengan ROI. Lalu lintas dan manajemen transportasi, supply listrik, dan infrastruktur keamanan menunjukkan pengaruh tidak signifikan terhadap ROI. Usaha pemerintah dalam meningkatkan proses pengaadaan pemerintah masih belum memadai karena masih kecilnya pengaruh terhadap EDBI Nigeria. World Bank sebaiknya memasukkan pengaruh sektor privat dalam indikator EDBI sebagai upaya menciptakan sinergi antara pemerintah dan sektor privat untuk peningkatan EDBI dan dampaknya pada ekonomi. Kata kunci: Ease of Doing Business, indeks kemudahan berbisnis, pengembalian investasi, investor, Bank Dunia
Comparative Analysis of the Determinant Factors of Return on Assets between Islamic Commercial Banks (BUS) and Islamic Business Units (UUS)
Authors: Nugroho Lucky , Mastur Akhmad Amien , Ulfa Ulfa , Wahyono Tri , Soeharjoto Soeharjoto 
Published: May 2021

Abstract: This study aimed to analyze and compare the factors that affect the return on assets (ROA) of Islamic commercial banks (BUS) and Islamic business units (UUS). This study’s independent variables are NPF, FDR, and MSMEs. The study used the quantitative method, with multiple regression approaches in analyzing the research data. The results of this study show that the BUS NPF has a negative and significant impact on the BUS ROA; the BUS FDR has a positive and insignificant impact on the BUS ROA; the BUS MSMEs portion of the BUS loan distribution has a negative and insignificant impact on the BUS ROA; the UUS NPF has a negative and significant impact on the UUS ROA; the UUS FDR has a positive and significant impact on the UUS ROA; and the MSMEs’ portion of the UUS loan distribution has a positive and significant impact on the UUS ROA.Keywords: BUS, UUS, Return on Asset, Non-Performing Financie, Financing to Deposit Ratio, MSME financing Analisis Perbandingan Determinan Faktor Return on Asset antara Bank Umum Syariah (BUS) dengan Unit Usaha Syariah (UUS)Abstrak: Penelitian ini bertujuan untuk menganalisa perbandingan variabel-variabel yang mempengaruhi return on asset pada Bank Umum Syariah (BUS) dengan Unit Usaha Syariah (UUS). Adapun variable-variabel bebas yang digunakan pada penelitian ini adalah non performing financing, financing to deposit ratio dan porsi penyaluran pinjaman usaha mikro, kecil dan menengah (UMKM). Metode yang digunakan adalah kuantitatif dengan pendekatan regresi berganda dalam melakukan analisa penelitian ini. Hasil dari penelitian ini diketahui bahwa NPF BUS berdampak negatif dan signifikan terhadap ROA BUS; FDR BUS berdampak postif dan tidak signifikan terhadap ROA BUS; porsi penyaluran pinjaman UMKM BUS berdampak negatif dan tidak signifikan terhadap ROA BUS; NPF UUS berdampak negatif dan signifikan terhadap ROA UUS; FDR UUS berdampak positif dan signifikan terhadap ROA UUS; Porsi penyaluran pinjaman UMKM UUS berdampak positif dan signifikan terhadap ROA UUS.Kata kunci: BUS, UUS, ROA, NPF, FDR, Pembiayaan UMKM
NOVEL FINDINGS OF PHOENIX DACTYLIFERA, DATES FRUIT EARLY-STAGE HABABUK FOR PHYTOCHEMICAL SCREENING, ANTIOXIDANT AND CYTOTOXIC POTENTIALS
Authors: AHAMMED SHAKKEELA YUSUF ERATTIL , ALMUTAIRI AREEJ MUHAMMED , AL-RASHIDI FATIMA SULIMAN , ALMUTAIRI OHOUD FAHAD 
Published: May 2021

Objective: The present study aims to investigate the phytochemical constituents, antioxidant, and cytotoxic activity of the total ethanolic extract of the hababuk stage of date’s fruits Phoenix dactylifera (PDHE).
Methods: Extracts PDHE obtained with shade dried and a powdered sample of hababuk stage of date fruits Phoenix dactylifera and subjected to phytochemical screening, in vitro antioxidant activity study by DPPH assay and ABTS assay, in vitro cytotoxic studies carried out for three different cell lines Lung Cancer (A549), Human cervical carcinoma (HeLa) and Breast Cancer (MCF)-7 cells by MTT method and brine shrimp lethality assay using standard procedure.
Results: The phytochemical study revealed the presence of important constituents like alkaloids, glycosides, phenolic, flavonoids, carbohydrate, proteins, amino acids, terpenoids, steroids, and saponins. The antioxidant studies of the PDHE compared with standard showed very excellent results IC50 values for DPPH activity and nitric oxide. A good result was also shown by ABTS when compared with that of standard. The brine shrimp lethality assay is considered a useful tool for preliminary assessment of toxicity. The extract showed excellent LC50 value, which correlates with cytotoxicity studies previously established. The MTT study results using the three different cell lines compared with the standard doxorubicin, promising results obtained for HeLa cell lines when compared with other cell lines.
Conclusion: Results obtained from the present work indicated that the hebabuk stage of date fruit is a promoising antioxidant and anticancer agent. Further study should be carried out to isolate the bioactive compound responsible for the activity.
ETHNOPHARMACOLOGICAL STUDY OF BRAIN OXIDATIVE STRESS IMPROVING POTENTIAL OF CURCUMIN IN INTOXICATED RATS
Authors: EL-SAYED FATEN IBRAHIM 
Published: May 2021

Objective: The following study aimed to investigate the efficacy of curcumin at preventing amikacin neurotoxicity
Methods: Twenty-four male Wister albino rats were randomly divided into four groups including-G (1): control group includes six rats, they were administered 0.5 ml of saline orally for 14 consecutive days. G (2): includes six rats; they were administered 200 mg/kg curcumin orally for 14 consecutive days. G (3): includes six rats, they were administered 300 mg/kg body weight/day of amikacin intraperitoneally for 14 consecutive days G (4): includes six rats, they were administered 200 mg/kg curcumin orally concurrently with 300 mg/kg body weight/day of amikacin. All animals were kept in the same conditions from feed, heat and humidity.
Results: According to the result obtained after sacrification of all animals after the end of 14 d, Results revealed that amikacin at the dose rate of 300 mg/kg b. wt for 14 d induces significant changes in oxidative stress markers compared to the control group, a significant reduction in CAT. SOD. GSH (1.51±0.16, 77.00±0.73 and 84.06±4.42) respectively compared to control (3.63±0.11, 98.48±0.18 and 117.05±0.52) along with a significant increase in MDA activity (219.02±3.34) compared to control group (180.42±0.19), That indicate oxidative stress effect of it. On the beneficial side rats received amikacin 300 mg/kg B. wt I/p concurrently with 200 mg/kg b. wt curcumin for successive 14day result in a significant increase in CAT. SOD. GSH (2.23±0.09,92.00±0.26, 102.25±1.71) and decrease in MDA concentration (139.23±3.89) compared to amikacin treated group levels along with histopathological changes appear in brain tissue in the group treated with amikacin include nuclear pyknosis and degeneration in some neurons in the hippocampus, multiple focal eosinophilic plaque formation in the striatum also this results enhanced by activated caspase-3 expression in the brain tissue following amikacin administration.
Conclusion: The present study proved that Oral administration of curcumin at the dose of 200 mg/kg for 14 d concurrently with amikacin significantly mitigates its neurotoxic and oxidative stress effects.
Passive nihilism and ontotheology: A reply to Husbands on derivative temporality
Authors: Smidt Austin Hayden 
Published: May 2021

AbstractConor Husbands’ defense and expansion of Elena Esposito's temporality of finance is a much-needed intervention. However, in this response essay, I will show a few of the fundamental weaknesses of Esposito's project, and by extension will highlight some shortcomings of Husbands’ defense-expansion. The point is not to dismiss either project; the goal is rather to bring attention to certain philosophical presuppositions that ground both, and that enclose each in what Markus Gabriel would call an ontotheological orientation. In short, Esposito and Husbands operate via an orientation that attempts to think ‘the world’ as an all-encompassing domain, despite claims to the contrary. How this occurs will be explained below, paying particular attention to the stakes of thinking from such an ontotheological orientation in and to the world. After first presenting Husbands’ argument, I develop some critiques of Esposito and Husbands via the work of Suhail Malik, Ray Brassier, Elie Ayache, Jon Roffe, and Quentin Meillassoux. I then open the aperture towards emerging trends in philosophy that contest the foundations upon which Esposito's project is built, in order to suggest more robust readings of finance and society. The work of Sergei Prozorov and Markus Gabriel will be the focus here, but these thinkers merely serve as stand-ins for larger trends in speculative- and neo-realism.
Building and protecting business through intellectual property rights
Authors: Purwanto Edy , Hidayaturrahman Mohammad 
Published: May 2021

Pagerungan Besar is one of the villages in Sapeken District which has quite a good marine and agricultural product potential. MSME actors in Pagerungan Besar are currently starting to develop, but there are concerns about the large number of counterfeit products that can damage the brand or product image that has been grown up. This activity was aimed to provide understanding to MSME actors in Pagerungan Besar Village regarding Intellectual Property Rights. Activities carried out in the form of socialization and assistance. This method is the right way to solve the problems experienced by MSME actors in Pagerungan Besar. There was 30 MSME actor who attended the socialization and mentoring activities. The results of this activity indicate that there is a significant change in the respondent's understanding of intellectual property rights. Before the socialization, only 5 participants (15%) knew and had heard of IPR, but after the socialization, 30 participants (100%) already understood IPR. Furthermore, assistance efforts must be carried out until the MSME actors have the rights to the works they own, be it trademarks, copyrights and, other intellectual property rights.
Teacher professional education coaching to produce high quality lesson plan
Authors: Sabilah Fardini , Abidasari Erlyna , Husamah H. 
Published: May 2021

The Teacher Professional Education program (Program Profesi Guru/PPG) equips the teachers’ lifelong teaching skills and improves pedagogical knowledge to lead a successful profession as a teacher. However, the real condition in the SMPN 4 Malang suggested the opposite results, portraying the struggle of some PPG graduates in understanding the K-13 based curriculum, its planning the lesson plan and implementation in their class. This article aims to describe the community service activities teacher professional education coaching to produce high quality lesson plan. The Community Service team reaches out their hands to answer their needs by constructing a coaching and mentoring program in three phases, initiation, implementation and evaluation. Initiation process was done through seminar and focused group discussion, whereas the implementation focused on assisting the revised lesson plan and evaluating the document with the constructed evaluation instrument, then lastly evaluation was done in the microteaching and reflection stage. The results shows that the teachers were already aware of the process standards and content standards of lessons plan, in facts there were still some components that in practice didn’t written properly. Besides, there were also some parts of the lesson plan contents which didn’t match each other. To sum up, after this project, it is highly expected that the PPG graduates’ teachers in SMPN 4 Malang have less difficulties in understanding the government education regulation, in order to plan a more attractive and productive lesson as well as generate self-evaluation tool for further analysis or study. It is suggested to teachers to upgrade their lesson plan by implementing STEAM approach, 4Cs skills and using innovative teaching methods, besides the teachers still need good knowledge and practice in implementing sorts of online teaching platforms.
Psikologi Tokoh dalam Novel Pulang Karya Leila S. Chudori (Kajian Psikoanalisis Sigmund Freud)
Authors: Rahman Fauzi 
Published: May 2021

Penelitian ini bertujuan untuk mengetahui psikologi tokoh dalam novel Pulang melalui analisis psikologis tokoh berdasarkan struktur kepribadian Freud yang terdiri atas id, ego, dan superego. Hasil yang dicapai dari penelitian ini yaitu bahwa Dimas Suryo lebih banyak memunculkan sifat ego karena dari 35 paragraf dalam 4 episode yang dibahas, muncul 15 paragraf yang menyatakan sifat ego. Selanjutnya, Tokoh Lintang Utara lebih banyak memunculkan sifat id karena dari 35 paragraf dalam 4 episode yang dibahas, muncul 13 paragraf yang menunjukkan sifat id. Tokoh terakhir, Segara Alam lebih banyak memunculkan sifat ego karena dari 22 paragraf dalam 2 episode yang dibahas, muncul 10 paragraf yang menunjukkan sifat ego.
Adición de un probiótico de Lactobacillus plantarum microencapsulado en el alimento para pollos
Authors: Jurado-Gámez Henry Armando , Zambrano-Mora Edward Johnny , Pazos-Moncayo Alvaro 
Published: May 2021

Introducción: En producción avícola el uso de antibióticos promotores del crecimiento es limitado, debido al incremento de resistencia bacteriana. Una alternativa evalúa los probióticos microencapsulados y su efecto en la salud intestinal. Objetivo: Determinar el efecto de Lactobacillus plantarum microencapsulado sobre parámetros intestinales e inmunológicos en pollos de engorde. Materiales y métodos: A 240 pollos Ross-308-AP de un día de nacidos se suministró alimento con o sin adición de probiótico bajo el siguiente modelo: sin probiótico-(T0), con probiótico comercial-(T1), con Lactobacillus plantarum microencapsulado-(T2) y sin microencapsular-(T3). Lactobacillus plantarum ATCC-8014 se microencapsuló mediante secado por aspersión, determinando su viabilidad en (%). Se evaluaron parámetros intestinales, morfo-histopatológicos e inmunológicos por Azul de Alcian, microscopia de barrido e inmunohistoquímica y la abundancia microbial por UFC/mL. Resultados: El microencapsulado confirió una viabilidad in vivo de Lactobacillus plantarum del 88,1%. El tratamiento T2 mejoró los parámetros inmunológicos y confirió beneficios intestinales con una abundancia de bacterias benéficas (Lactobacillus) de (9,13x105-UFC/mL), significativamente mayor a la encontrada en los tratamientos T1 (8,91x105) y T3 (8,23x105) y el control T0 (9,18x104), (p<0,05). Conclusiones: La adición de Lactobacillus plantarum microencapsulado en alimento para pollos mejora parámetros inmunológicos y confiere mayor abundancia de bacterias benéficas presentes en la microbiota intestinal.