bluuebunny/crossref_metadata_2025_split huggingface dataset:
Psychometric Properties of A Silhouette Rating Scale Assessing Current And Ideal Body Size And Body Dissatisfaction In Adults
Authors: Lombardo Caterina , Cerolini Silvia , Esposito Rita Maria , Lucidi Fabio 
Published: June 2021

Abstract
Purpose: The study aims at validating a new pictorial tool, the Silhouette Rating Scale (SRS). It consists of a series of 9 female or male silhouettes. It was created to assess current and ideal body size evaluation, and body dissatisfaction. Our aims were to test the concurrent, convergent and discriminant validity of the scale, evaluating possible gender differences.Method: A first sample of 754 young adults (age M=26.10±8.50, males N=218) and a second sample of 210 young adults (age M=21.19±3.22, males=43) completed the Silhouette Rating Scale, and other self-report measures assessing body size evaluation, disordered eating, body satisfaction, depression, emotion regulation and insomnia. Results: Statistical analyses performed on the first sample largely support the concurrent validity of the scale. Results obtained from the second sample confirm its convergent validity, showing strong correlations with the Contour Drawing Rating Scale. Additionally, the correlations performed between the three responses of the Silhouette Rating Scale and other measures of eating disorders, depression, insomnia and emotion regulation indicated a good discriminant validity, though some of the variables measured seem to be significantly correlated. Conclusions: The Silhouette Rating Scale is a reliable and valid tool for assessing current body size, body ideal and body dissatisfaction as compared as other widely used scales. It guarantees the universality of use thanks to the absence of details related to ethnicity or culture and at the same time, maintaining a right level of realism. Future studies will evaluate test-retest validity and its potential within clinical populations.Leve of Evidence: Level V, descriptive cross-sectional study
Expression Profiling of Tumorigenesis Genes in Patients of Laryngeal Papillomatosis
Authors: Khan Muhammad Yasir , Tahir Tehreem , Khan Saif Ullah , Khan Muhammad Sarwar , Mansoor Qaisar 
Published: June 2021

Abstract
Recurrent Laryngeal papillomatosis (RLP) is a disease of the aero-digestive junction superimposed at the upper respiratory tract. Low risk human papillomavirus type 6 and 11 are infectious agents in RLP. Mainstay of treatment for RLP is CO2 laser vaporization for debulking of papilloma. Understanding of the gene changes at expression level might prove helpful for RLP management. The study was designed to evaluate the changes in tumorigenesis genes in RLP cases to mark the severity and aggression at gene expression level for disease management. Tissue samples and peripheral blood samples were acquired from clinically diagnosed RLP patients of age < 12 years undergoing CO2 laser vaporization. Control samples were taken from the normal thyroid tissue of individuals undergoing thyroidectomy. Relative quantitation of gene expression was done by real time polymerase reaction using cDNA samples. Up regulation of CXCL12/ CXCR4 signaling axis, parallel increase in GLUT-1 and over expression of IGF-I, EGFR and ER-α gene product was observed in RLP. On the other hand HIF-1a levels not discerned elevated along with VEGF, PIK3 and AKT gene expression profile. The expression analysis has provoked the possible strategies which can be planned to treat RLP by adjuvant and tailored medication to reduce multiple surgeries.
Interpreting SAXS Data Recorded On Cellulose Rich Pulps
Authors: Larsson Tomas , Stevanic-Srndo Jasna , Roth Stephan V. , Söderberg Daniel 
Published: June 2021

Abstract
A simulation method was developed for modelling SAXS data recorded on cellulose rich pulps. The modelling method is independent of the establishments of separate form factors and structure factors and was used to model SAXS data recorded on dense samples. An advantage of the modelling method was that it made it possible to connect experimental SAXS data to apparent average sizes of particles and cavities at different sample solid contents. Experimental SAXS data could be modelled as a superposition of a limited number of simulated intensity components and gave results in qualitative agreement with CP/MAS 13C-NMR data recorded on the same samples. For the water swollen samples, results obtained by the SAXS modelling method and results obtained from CP/MAS 13C-NMR measurements, agreed on the ranking of particle sizes in the different samples. The SAXS modelling method is dependent on simulations of autocorrelation functions. The time needed for simulations could be reduced by rescaling of simulated correlation functions, due to their independence of the choice of step size in real space. This way an autocorrelation function simulated for a specific sample could be used to generate SAXS intensity profiles corresponding to all length scales for that sample and used for efficient modelling of the experimental data recorded on that sample.
Unified Performance-Based Design of RC Dual system
Authors: MIBANG DURGA , Choudhury Satyabrata 
Published: June 2021

Abstract
A dual system building is comprised of frames and shear walls. In dual system the shear wall predominantly carries the lateral loads arising out of earthquake or wind. Frame is primarily designed for vertical load along with a fraction of lateral load. The force-based method of design or codal design method can hardly design building for pre-defined target objectives. The alternative method of design is displacement-based design (DBD). Available displacement-based design, like, Direct Displacement-Based design (DDBD) had been applied to dual system. However, DDBD method satisfied only drift criteria and was silent about the performance level. Also, the member sizes had to be obtained through iterations. Unified Performance-Based Design (UPBD) method can accommodate both drift and performance level as target design criteria. In the present study the theoretical background of UPBD method for dual system has been explained and detailed design steps have been highlighted. The method has been validated through several dual system buildings with different target design criteria. Dual system buildings have been designed using UPBD method for target objectives of (i) Immediate Occupancy performance level (PL) with drift 1%, (ii) life Safety PL with drift 2% and, (iii) Collapse Prevention PL with drift 3%. The nonlinear evaluation of the designed buildings shows that in all the cases the target design criteria have been fulfilled. The UPBD method of dual system also gives the member sizes in the beginning of the design and thus avoids iteration in design.
Inner ear biomechanics reveals Late Triassic origin of mammalian endothermy
Authors: Araujo Ricardo , David Romain , Benoit Julien , Jacqueline Lungmus , Spoor Fred , Stoessel Alexander , Barrett Paul , Maisano Jessica , Ekdale Eric , Orliac Maeva , Luo Zhe-Xi , Martinelli Agustin , Hoffman Eva , Sidor Christian , Martins Rui , Angielczyk Kenneth 
Published: June 2021

Abstract
Endothermy (“warm-bloodedness”) underpins the ecological dominance of mammals and birds in diverse environmental settings^1-3. However, it is unclear when this crucial feature emerged during mammalian evolutionary history, as most fossil evidence is ambiguous^4-25. Here, we show that new information on this key evolutionary transition can be obtained from the morphology of the endolymph-filled semicircular ducts of the inner ear that monitor head rotations and are essential for motor coordination, navigation, and spatial awareness^26-31. Increased body temperature during the ectotherm–endotherm transition of mammal ancestors would decrease endolymph viscosity, negatively impacting the biomechanics of the semicircular ducts^32,33, while simultaneously increasing activity levels^34,35 required improved performance^36. Specific morphological changes to the membranous ducts and enclosing bony canals were, therefore, necessary to maintain optimal functionality. We track these morphological changes in 341 vertebrates, including 56 extinct synapsids, and show that canals with relatively thin cross-sections and small radii of curvature are indicative of mammalian endothermy. This inner ear morphotype evolved abruptly ~233 million years ago, during the Late Triassic, in Mammaliamorpha. Our conclusion differs from previous suggestions3-17, and we interpret most stem-mammals as ectotherms. Endothermy as a crucial physiological characteristic joins other distinctive mammalian features that arose during this period of climatic instability^37-39.*Ricardo Araújo and Romain David contributed equally to this work.
Unification of treatments and interventions for tinnitus patients (UNITI): a study protocol for a multi-center randomized clinical trial
Authors: Schoisswohl Stefan , Langguth Berthold , Schecklmann Martin , Boecking Benjamin , Cederroth Christopher , Chalanouli Dimitra , Cima Rilana , Denys Sam , Dettling-Papargyris Juliane , Escalera-Balsera Alba , Espinosa-Sanchez Juan Manuel , Gallego-Martinez Alvara , Giannopoulou Efi , Hidalgo-Lopez Leyre , Hummel Michael , Kikidis Dimitris , Koller Michael , Escámez Jose Antonio López , Marcrum Steven , Markatos Nikolaos , Martin-Lagos Juan , Martinez-Martinez Maria , Martinez-Martinez Marta , Ferron Maria Mata , Mazurek Birgit , Mueller-Locatelli Nicolas , Neff Patrick , Oppel Kevin , Perez-Carpena Patricia , Robles-Bolivar Paula , Rose Matthias , Schiele Tabea , Schiller Axel , Simoes Jorge , Stark Sabine , Staudinger Susanne , Stege Alexandra , Verhaert Nicolas , Schlee Winfried 
Published: June 2021

Abstract
Background
Tinnitus represents a relatively common condition in the global population accompanied by various comorbidities and severe burden in many cases. Nevertheless, there is currently no general treatment or cure, presumable due to the heterogeneity of tinnitus with its wide variety of etiologies and tinnitus phenotypes. Hence, most treatment studies merely demonstrated improvement in a subgroup of tinnitus patients. The majority of studies are characterized by small sample sizes, unstandardized treatments and assessments or applications of intervention targeting only a single organ level. Combinatory treatment approaches, potentially targeting multiple systems as well as treatment personalization might provide remedy and enhance treatment responses. The aim of the present study is to systematically examine established tinnitus therapies both alone and in combination in a large sample of tinnitus patients. Further it wants to provide the basis for personalized treatment approaches by evaluating a specific decision support system developed as part of an EU-funded collaborative project (Unification of treatments and interventions for tinnitus patients; UNITI-project).
Methods/ Study design:
This is a multi-center parallel-arm randomized clinical trial conducted at five different clinical sites over the EU. The effect of four different tinnitus therapy approaches (sound therapy, structured counselling, hearing aids, cognitive behavioral therapy) applied over a time period of 12 weeks as a single or rather a combinatory treatment in a total number of 500 chronic tinnitus patients will be investigated. Assessments and interventions are harmonized over the involved clinical sites. The primary outcome measure focuses on the domain tinnitus distress assessed via the Tinnitus Handicap Inventory.
Discussion
Results and conclusions from the current study might not only provide an essential contribution to combinatory and personalized treatment approaches in tinnitus but could also provide more profound insights in the heterogeneity of tinnitus, representing an important step towards a cure for tinnitus.
Trial registration:
ClinicalTrials.gov: NCT04663828. Registered on 11. December 2020
Optimization of Process Parameters during Hydroforming of Tank Bottom using NSGA-III Algorithm
Authors: Zhang Zaifang , Xu Feng , Sun Xiwu 
Published: June 2021

Abstract
The hydroforming technology can realize overall forming of large storage tank’s bottom, but the quality is affected by many technological parameters. In view of wrinkling and cracking defects of integral storage tank’s bottom in hydroforming, a multi-objective optimization model is established for process parameters include pre-expansion pressure, hydraulic pressure, blank holder force and fillet radius of blank holder. Based on finite element simulation, the surrogate model between process parameters and quality criteria is established using Kriging technique. NSGA-III is used to determine optimal process parameters when storage tank’s bottom reaches targets include minimum wall thickness variations, minimum fracture trend, minimum flange wrinkle and minimum wrinkle trend. Compared with Particle swarm optimization (PSO) algorithm, NSGA-III algorithm is more suitable to solve this optimization problem. The validity of this method and accuracy of the results are verified by simulation experiments.
WITHDRAWN: A multi-level qualitative analysis of sensitive-intervention stunting program: from regulation to action
Authors: Purnama Tri Bayu , Arrazy Syafran , Wangge Grace 
Published: June 2021

Abstract
Objectives : The multisectoral problem of stunting with sensitive interventions is still a public health problem. This problem is due to complex factors that affect stunting programs across sectors to accelerate the stunting program for non-nutrition programs. This study aims to identify challenges in implementing sensitive interventions on stunting from regulation to implementation of activities. Methods : A qualitative multilevel approach was used for this research by conducting in-depth interviews, observation, and document review on the supply and demand aspects of the stunting-sensitive intervention program. The District of Health as the first level in the regulator, the Public health center as the implementer of the activity, and the community as the target of the activity were interviewed about the impact of regional regulatory innovations on stunting prevalence. Results This study explains that the families of stunting infants are not familiar with sensitive intervention activities and are still focused on specific packages. Coordination and collaboration, both intern level and between levels, have not been maximally implemented. The development of innovations in regional regulations has no impact on public health indicators both before and after the design is implemented. Conclusion for practices This research concludes that deploying cadres, transforming regulation inovation to social inovation and program managers trainning are crucial to accelerate sensitive intervention program.
Experimental Evaluation on Components of Shear resistance of Reinforced Concrete Beams with Shear Reinforcement Provided
Authors: Joshi Sreenivasa Prasad , P Poluraju 
Published: June 2021

Abstract
The contribution of aggregate interlocking and dowel force in shear strength of reinforced concrete beams was topic of research for many years. The precise forecasts of shear behavior were challenging to determine due to complication involved. The existing theories had focused on aggregate interlocking force and shear resistance arising due to concrete compression zone, neglecting the contribution of dowel force despite considering as significant constituent in shear transfer mechanism. The present investigation focuses on cogitating all components in shear transfer mechanism by providing shear reinforcement and keeping clear cover and effective span to depth ratio constant. Sixteen specimens were considered for parametric study by employing suitable variables such as increase in strength of concrete and variation in flexural reinforcement. Eight specimens were conventional beams and the remaining eight specimens were provided with preformed cracks. Moment vs. displacement curvature and strain vs. moment curvature were plotted to evaluate shear at uncracked compression zone and accordingly aggregate interlocking force and dowel force were determined based on the empirical formulas proposed. From the result it was confirmed that contribution of aggregate interlocking force and dowel force were insignificant and shear resistance due to uncracked compression zone is the sole contributor in shear transfer mechanism. Structural behavior of concrete beams was also studied and it was confirmed that beams with preformed cracks exhibited better structural behavior when related to conventional beams.
Survey Of Male And Female Frogs (Pyxicephalus Edulis) And Assosciated Toxic And Non Toxic Elements
Authors: Ediagbonya Thompson Faraday , Ogunjobi Adedayo Johnson , Adenikinju Ademola Charles 
Published: June 2021

Abstract
The present research was performed to determine the concentration of heavy metals in the male and female specimens of the identified frog species: pyxicephalus edulis collected from the Igbekebo River in Igbekebo, Ese-odo local government. Adult frogs (male and female) were collected from the river bank, and sediment samples and water samples were also collected at five ( 5) separate locations in the river. The frogs were dried separately at 1050C for 6 hrs and then crushed into small particles (powder form). The sediment samples were air-dried for three days. Elemental components in frog samples and sediment samples were analyzed using Proton Induced X-Ray Emission (PIXE). Physiochemical parameters and heavy metals of the water samples were also analyzed. The findings showed that the concentrations of Si, P, Cl, Ni, Zn and Cd were higher in Male frog while Mg, Al, K, Ca, Ti, V, Cr, Mn, Fe, Co, Cu, Zr, Pb and Sn were higher in female frogs, the explanation for this variability is not known but may be due to variations in the genetic make-up of Male and Female frogs. The concentration of heavy metals in both male and female frogs was substantially higher relative to the available WHO limits. The mean concentration of elemental constituents in sediment was higher than the IAEA limit. The values of enrichment and the Igeo values were very high.
Intelligent centralized traffic management of a rapid transit system under heavy traffic
Authors: Baranov L. A. , Sidorenko V. G. , Balakina E. P. , Loginova L. N. 
Published: June 2021

Aim. In today’s major cities, increased utilization and capacity of the rapid transit systems (metro, light rail, commuter trains with stops within the city limits) – under condi[1]tions of positive traffic safety – is achieved through smart automatic train traffic management. The aim of this paper is to choose and substantiate the design principles and architecture of such system.Methods. Using systems analysis, the design principles and architecture of the system are substantiated. Genetic algorithms allow automating train traffic planning. Methods of the optimal control theory allow managing energy-efficient train movement patterns along open lines, assigning individual station-to-station running times following the principle of mini[1]mal energy consumption, developing energy-efficient target traffic schedules. Methods of the automatic control theory are used for selecting and substantiating the train traffic algorithms at various functional levels, for constructing random disturbance extrapolators that minimize the number of train stops between stations.Results. Development and substantiation of the design principles and architecture of a centralized intelligent hierarchical system for automatic rapid transit traffic management. The distribution of functions between the hierarchy levels is described, the set of subsystems is shown that implement the purpose of management, i.e., ensuring traffic safety and comfort of passengers. The criteria are defined and substantiated of management quality under compensated and non-compensated disturbances. Traffic management and target scheduling automation algorithms are examined. The application of decision algorithms is demonstrated in the context of uncertainty, use of disturbance prediction and genetic algorithms for the purpose of train traffic planning automation. The design principles of the algorithms of traffic planning and management are shown that ensure reduced traction energy consumption. The efficiency of centralized intelligent rapid transit management system is demonstrated; the fundamental role of the system in the digitalization of the transport system is noted.Conclusion. The examined design principles and operating algorithms of a centralized intelligent rapid transit management system showed the efficiency of such systems that ensured by the following: increased capacity of the rapid transit system; improved energy efficiency of train traffic planning and management; improved train traffic safety; assurance of operational traffic management during emergencies and major traffic disruptions; improved passenger comfort.
Risk-oriented approach to life cycle contract implementation of weapons and military equipment
Authors: Dubovsky V. А. , Dubovskaya N. I. , Nikolaev А. S. 
Published: June 2021

Aim. Today, the development and operation of weapons and military equipment is characterized by fast-growing customer requirements, which, in turn, leads to their increased technical complexity and cost. It is obvious that maintaining the required physical and operational characteristics of high-technology weapons and military equipment by the users is not always possible due to a number of reasons, including insufficient capabilities of the service units that do not have the required personnel, assets and competences. In turn, the manufacturers involved in the delivery of the government defence order are also interested in shaping long-term relations with the customer allowing to build a platform for sound progress. One of the possible solutions for such interaction between the customer and the contractor used worldwide and in Russia is public-private partnership in the form of life cycle contracts. Despite the obvious advantages, its introduction into the practice of weapons and military equipment life cycle is hampered by a number of adverse factors (insufficiencies in the regulatory framework and technical standards, poor level of information technology deployment in LC management) that need to be overcome in terms of both scientific and practical considerations. It is perfectly clear that developing a tool that would allow mitigating a full spectrum of problems as part of this study would be an extremely challenging task. Given the above, the paper aims to examine risks as one of the aspects of this complex problem that implies the development of a new approach to the interaction of the parties involved in a life cycle contract for weapons and military equipment, taking into account the current conditions, interests, goals and objectives. It involves comprehensive analysis of uncertainty and the whole spectrum of possible risks associated with the weapons and military equipment life cycle processes. Methods. The managerial decision-making is based on the decision tree method that allows dividing the complex decision-making problem into component tasks and obtaining quantitative risk estimates, thus developing an adequate system of measures for the prevention of event risks and reduction of their negative consequences. Results. Based on the proposed methodological framework, a risk management algorithm has been developed, a matrix has been defined for assessing risks and their impact on the temporal and technical characteristics, as well as the costs of a project. Conclusion. The suggested approach is universally applicable and can be used by both the officials of military authorities in the process of scientific support of LCC implementation, and by the management of defense contractors as they develop their interaction with the military authorities responsible for the creation and operation of weapons and military equipment.