bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of calcitonin gene-related peptide on model mice with acute pancreatitis
Authors: Hu Jianxiong , Lin Yanya , Chen Shijun , Cai Yangfang , Chen Zhiwei , Lin Wei 
Published: March 2021

Abstract

Objectives
To establish model mice with acute pancreatitis (AP) and study influence of calcitonin gene-related peptide (CGRP) on AP.

Methods
The model mice with AP were firstly established by intraperitoneal injection of successive six doses of caerulein (100 μg/kg) and one dose of lipopolysaccharide (10 mg/kg). The intraperitoneal injection of CGRP (100 μg/kg) was performed to investigate influence of CGRP on AP, mainly involving the determination of amylase activity and the expression of CGRP and CD20+ B lymphocytes.

Results
CGRP on mice with AP could significantly reduce the severity of pancreatic pathological injury, the activity of amylase and the expression of CD20+ B lymphocytes. CGRP was significantly expressed in pancreatic tissue with AP, but CGRP receptor antagonist down-regulated the expression of CGRP and increased the number of CD20+ B lymphocytes, confirming the protective effect of CGRP on pancreatic tissue.

Conclusions
We preliminarily conclude that CGRP could significantly improve the pancreatic lesions and inflammatory infiltration of pancreas in mice with AP, and reduce the damage of pancreatic acinar cells, by mainly increasing blood flow and blood flow velocity of pancreas to improve the pancreatic microcirculation and effectively reducing the permeability of the microvessels to decrease the pathological damage degree of AP.
The Role of Private Insurance in Governing Work-Related Risks: A Law and Economics Perspective
Authors: Philipsen Niels J. , Faure Michael G. 
Published: March 2021

AbstractThis contribution focuses on the governance of industrial accidents and occupational diseases. Prevention of work-related accidents and diseases and compensation of employee-victims can be the subject of public regulation, such as OHS regulation and social security. However, also private actors may be involved in the regulation of work-related accidents, especially when compensation of damage caused by work-related risks is not (sufficiently) covered by public regulation. These private actors include representatives of employers and employees, but may also include private insurers. In some jurisdictions liability insurers provide supplementary cover for OHS risks and policy-makers often expect that the monitoring by liability insurers will increase safety at work. The main research question addressed in this paper is whether insurers (and more particularly insurers of employers’ liability) are indeed able to contribute to safety at work. Taking a law and economics perspective, we expect that this depends crucially on the possibilities insurers have to control moral hazard and adverse selection. However, the extent to which liability insurers have a financial interest in combatting these phenomena plays an important role. That may crucially depend upon the generosity of the public compensation scheme. First, we recapitulate the economic theory of insurance to the extent that it relates to work-related risks. Second, we address the question whether in some jurisdictions insurers have actually made use of these instruments, based on a literature survey. Third, we examine information on insurance policies offered by insurers in The Netherlands and the United Kingdom, to analyse to what extent theory matches practice.
Troubleshooting algorithms: A book review of Weapons of Math Destruction by Cathy O’Neil
Authors: Berry Pauline 
Published: March 2021

Fact: we no longer control our lives, algorithms do. Mortgage-backed securities, college rankings, online advertising, law enforcement, human resources, credit lending, insurance, social media, politics, and consumer marketing; algorithms live within each one of these – collecting, segmenting, defining, and planting each one of us into arbitrary, unassailable buckets. The algorithms and the data that feed this process is what data scientist and international bestselling author, Cathy O’Neil, calls Weapons of Math Destruction (WMDs). In her captivating and frankly, bone-chilling account of the power amassed by algorithms, O’Neil sheds much needed light into the seemingly omnipotent world of destructive algorithms.

Keywords: algorithms, algorithmic transparency, algorithmic bias, communications, public relations, ethics, data, predictive models
Blood Flow Restriction Does Not Promote Additional Effects on Muscle Adaptations When Combined With High-Load Resistance Training Regardless of Blood Flow Restriction Protocol
Authors: Teixeira Emerson Luiz , Ugrinowitsch Carlos , de Salles Painelli Vitor , Silva-Batista Carla , Aihara André Yui , Cardoso Fabiano Nassar , Roschel Hamilton , Tricoli Valmor 
Published: March 2021

Abstract
Teixeira, EL, Ugrinowitsch, C, de Salles Painelli, V, Silva-Batista, C, Aihara, AY, Cardoso, FN, Roschel, H, and Tricoli, V. Blood flow restriction does not promote additional effects on muscle adaptations when combined with high-load resistance training regardless of blood flow restriction protocol. J Strength Cond Res 35(5): 1194–1200, 2021—The aim of this study was to investigate, during high-load resistance training (HL-RT), the effect of blood flow restriction (BFR) applied during rest intervals (BFR-I) and muscle contractions (BFR-C) compared with HL-RT alone (no BFR), on maximum voluntary isometric contraction (MVIC), maximum dynamic strength (one repetition maximum [1RM]), quadriceps cross-sectional area (QCSA), blood lactate concentration ([La]), and root mean square of the surface electromyography (RMS-EMG) responses. Forty-nine healthy and untrained men (25 ± 6.2 years, 178.1 ± 5.3 cm and 78.8 ± 11.6 kg) trained twice per week, for 8 weeks. One leg of each subject performed HL-RT without BFR (HL-RT), whereas the contralateral leg was randomly allocated to 1 of 2 unilateral knee extension protocols: BFR-I or BFR-C (for all protocols, 3 × 8 repetitions, 70% 1RM). Maximum voluntary isometric contraction, 1RM, QCSA, and acute changes in [La] and RMS-EMG were assessed before and after training. The measurement of [La] and RMS-EMG was performed during the control sessions with the same relative load obtained after the 1RM test, before and after training. Similar increases in MVIC, 1RM, and QCSA were demonstrated among all conditions, with no significant difference between them. [La] increased for all protocols in pre-training and post-training, but it was higher for BFR-I compared with the remaining protocols. Increases in RMS-EMG occurred for all protocols in pre-training and post-training, with no significant difference between them. In conclusion, despite of a greater metabolic stress, BFR inclusion to HL-RT during rest intervals or muscle contraction did not promote any additive effect on muscle strength and hypertrophy.
O Batismo: suas origens na Idade Média e seus usos e significados para os escravos na Freguesia de Nossa Senhora da Vitória, em São Luís, Maranhão (1804-1806)
Authors: Cuba Tayná Silva 
Published: March 2021

O presente estudo trata do sacramento do Batismo, a importância que ele adquiriu desde a Idade Média e seus significados, quanto modo de inserção dos sujeitos escravizados em uma sociedade escravocrata-cristã. Nesse sentido, procurou-se observar as reminiscências do rito do período medieval que perpassaram diferentes recortes temporais, relacionando-o com os assentos de batismos do Livro de Registros de Batismos da Freguesia Nossa Senhora da Vitória – Igreja Catedral (ano 1804 – 1806), em São Luís, na época capital da província do Maranhão.Palavras-chave: Batismo, Idade Média, Escravidão. AbstractThe present study is about the sacrament of Baptism, the importance it has acquired since the Middle Ages and its meanings as a way of inserting the enslaved subjects in a Christian-slave society. In this sense, we tried to observe the reminiscences of the rite of the medieval period that permeated different temporal clippings, relating it to the baptism seats of the Livro de Registros de Batismos da Freguesia Nossa Senhora da Vitória – Igreja Catedral (year 1804 - 1806), in São Luís, at the time capital of the province of Maranhão.Keywords: Baptism; Middle Ages; Slavery.
A Ara Pacis Augustae na Itália fascista: breve análise sobre a reagrupação dos fragmentos a partir do Cinegiornale Luce
Authors: Assis Augusto Antônio de 
Published: March 2021

O artigo pretende discutir a relação de apropriação do passado romano pelo regime fascista através da mobilização da Ara Pacis Augustae nos cinejornais do Istituto Luce. Para tanto, inicialmente objetivamos traçar um percurso analítico sobre o culto della romanità, mesclando bibliografia especializada e discursos de Benito Mussolini. A posteriori, analisaremos o cinejornal de 01 de dezembro de 1937, do Istituto Luce, em que os fragmentos de Florença da Ara Pacis são condicionados para o transporte a Roma. O esforço final consistirá na problematização das relações estabelecidas entre o conceito de Pax e a Ara Pacis, na Roma Antiga e na Itália Fascista, e os Usos do passado empreendidos por Augusto e Mussolini por meio do monumento.Palavras chave: Usos do passado; Ara Pacis Augustae; Culto della romanità; cinejornal. AbstractThe article intends to discuss the relation of appropriation of the Roman past by the fascist regime through the mobilization of Ara Pacis Augustae in the newsreels of the Istituto Luce. Therefore, we initially aimed to trace an analytical path about the culto della romanità, mixing specialized bibliography and speeches by Benito Mussolini. A posteriori, we will analyze the newsreel of December 1, 1937, of the Istituto Luce, in which the fragments of the Ara Pacis in Florence are conditioned for transport to Rome. The final effort will be to problematize the relations established between the concept of Pax and Ara Pacis, in Ancient Rome and in Fascist Italy, and the Uses of the past undertaken by Augusto and Mussolini through the monument.Keywords: Uses of the past; Ara Pacis Augustae; Culto della romanità; newsreel.
Avaliação no ensino de História: uma experiência no Colégio de Aplicação/UFSC
Authors: Lunardelli Diego , Pinheiro Machado Marco Antônio 
Published: March 2021

O artigo apresenta uma análise sobre as possibilidades de entender a avaliação como parte central do processo de ensino/aprendizagem em História. Essa reflexão surge como produto da atividade de regência de classe pertinente à disciplina de Estágio Supervisionado em História II, na Universidade Federal de Santa Catarina. Portanto, há nesta discussão elementos empíricos (resultados das avaliações formativas, avaliação somativa e autoavaliação da turma), que, em diálogo com referenciais teóricos, permitiram-nos tecer considerações que apontam para resultados propositivos quanto ao uso sistemático de avaliações, por meio de atividades com fontes históricas. Dessa maneira, esse trabalho estabelece uma comparação entre avaliações objetivas e formativas, demonstrando que a utilização de avaliações formativas com fontes históricas pode contribuir para um melhor processo de ensino/aprendizagem.Palavras-Chave: Estágio Supervisionado de História; Colégio de Aplicação; Avaliação; Ensino de História. AbstractThe article presents an analysis of the possibilities of understanding evaluation as a central part of the teaching/learning process in History. This reflection arises as a product of the class activity pertinent to the subject of Supervised Internship in History II, at the Federal University of Santa Catarina. Therefore, there are empirical elements in this discussion (results of formative assessments, summative assessment and self-assessment of the class), which, in dialogue with theoretical references, allowed us to make considerations that point to propositional results regarding the systematic use of assessments, through activities with historical sources. Thus, this paper establishes a comparison between objective and formative assessments, demonstrating that the use of formative assessments with historical sources can contribute to a better teaching/learning process.Keywords: Supervised History Internship; Laboratory School; Evaluation; History teaching.
Belief in Conspiracy Theories About covid-19 Amongst Venezuelan Students: A Pilot Study
Authors: Andrade Gabriel 
Published: March 2021

Although researchers have not satisfactorily tracked the origins of COVID-19, there are no indications that this virus has been engineered by human beings. Yet, conspiracy theories blaming either the United States or China, are increasingly popular. For a greater research project to be developed in the future, a pilot study was done, where 165 Venezuelan students were asked in a survey to rate their agreement with conspiracy theories about COVID-19. Although the majority of subjects were skeptical of these claims, the percentage of acceptance of COVID-19 conspiracy theories was still fairly high, if compared to other medical conspiracy theories. Educational level was not a significant predictive factor in acceptance of these conspiracy theories. Acceptance of other conspiracy theories has a significant relation, but only if they cohere with ideological positioning in the Venezuelan context. Likewise, ethnicity also correlated with belief in covid-19 conspiracy theories, but again, mediated by political alignments in the Venezuelan context.

How to cite this article: Andrade, G. (2021). Belief in conspiracy theories about covid-19 amongst Venezuelan students: A pilot study. Revista Colombiana de Psicología, 30(1), 79-88. https://doi.org/10.15446/rcp.v30n1.87357
Stress-Drop Estimates for Induced Seismic Events in the Fort Worth Basin, Texas
Authors: Jeong Seong Ju , Stump Brian W. , DeShon Heather R. , Quinones Louis 
Published: March 2021

ABSTRACTEarthquakes in the Fort Worth basin (FWB) have been induced by the disposal of recovered wastewater associated with extraction of unconventional gas since 2008. Four of the larger felt earthquakes, each on different faults, prompted deployment of local distance seismic stations and recordings from these four sequences are used to estimate the kinematic source characteristics. Source spectra and the associated source parameters, including corner frequency, seismic moment, and stress drop, are estimated using a modified generalized inversion technique (GIT). As an assessment of the validity of the modified GIT approach, corner frequencies and stress drops from the GIT are compared to estimates using the traditional empirical Green’s function (EGF) method for 14 target events. For these events, corner-frequency residuals (GIT−EGF) have a mean of −0.31 Hz, with a standard deviation of 1.30 Hz. We find consistent mean stress drops using the GIT and EGF methods, 9.56 and 11.50 MPa, respectively, for the common set of target events. The GIT mean stress drop for all 79 earthquakes is 5.33 MPa, similar to estimates for global intraplate earthquakes (1–10 MPa) as well as other estimates for induced earthquakes near the study area (1.7–9.5 MPa). Stress drops exhibit no spatial or temporal correlations or depth dependency. In addition, there are no time or space correlations between estimated FWB stress drops and modeled pore-pressure perturbations. We conclude that induced earthquakes in the FWB occurring on normal faults in the crystalline basement release pre-existing tectonic stresses and that stress drops on the four sequences targeted in this study do not directly reflect perturbations in pore-fluid pressure on the fault.
Changes and evolution among SARS-COV-2 hospitalised patients in terms of severity, mortality and virus genome in a Spanish cohort
Authors: Aznar-Gimeno Rocío , Paño-Pardo J. Ramón , Esteban Luis M. , Labata-Lezaun Gorka , Esquillor-R M. José , Lanas Angel , Abadía-Gallego David , Diez-Fuertes Francisco , Tellería-Orriols Carlos , del-Hoyo-Alonso Rafael , Serrano M. Trinidad 
Published: March 2021

Abstract
A comparison between pandemic waves could help to understand the evolution of this disease. The objective of this work was to study the evolution of COVID-19 hospitalized patients on different pandemic waves in terms of severity and mortality.
We performed an observational retrospective cohort study of hospitalized patients (5,220) with SARS-CoV-2 infection from February to September in Aragon, Spain. In a comparative way, we analyzed ICU admission and 30-day mortality, clinical characteristics and risk factors, of first and second waves. SARS-CoV-2 virus genome were analyzed in 236 samples.
Patients in the first wave (n=2,547) were older (74 y, IQR: 60-86 vs. 70 y, IQR: 53-85; p<0.001) and showed worse clinical and analytical parameters related to severe COVID-19 than in the second wave (n=2,673). The probability of ICU admission at 30 days was 16% and 10% in the first and second wave, respectively (p<0.001). The cumulative 30-day mortality rates were 38% in the first wave and 32% in the second one (p=0.007). Survival differences were observed among patients aged 60 to 80 years. There was variability among death risk factors and virus genome between waves.
Therefore, the two COVID-19 pandemic waves analyzed were different, in terms of disease severity and mortality.
Empowering prosumers to trade renewable energy can benefit the individual, the community, and the grid
Authors: Pena-Bello Alejandro , Parra David , Herberz Mario , Tiefenbeck Verena , Patel Martin , Hahnel Ulf 
Published: March 2021

Abstract
Peer-to-peer (P2P) exchange of renewable energy is an attractive option to engage and empower citizens to actively participate in the energy transition. Whereas previous research has provided techno-economic models and technological solutions to enable P2P energy trading, little is yet known about citizen preferences for solar power trading. Importantly, the impacts of community members’ trading decisions across scales such as individual electricity bills, community autarky, and grid stability remain unknown. Here, we assess actual P2P trading strategies based on an experimental study with German homeowners and simulate how retrieved decision-making strategies impact the performance of P2P communities across the three scales. Our findings suggest that community autarky is higher in P2P communities than in self-consumption communities, even if self-consumption communities search to maximize autarky (an autarky paradox). We show that actual prosumer decision-making may lead to benefits at the individual (reduced energy bills), community (higher community autarky), and grid level (reduced stress).
Postoperative bleeding in a patient with appendiceal mucinous adenocarcinoma and liver dysfunction patient: A case-report
Authors: Sun MingKun , Niu Xiaohua , Tang Ying , Mo Wenzhong , Xin Haiyang , Tang Chaoming , Qi Ling 
Published: March 2021

Abstract
Background: Appendiceal malignant tumors are rare in the clinic, and the incidence rate of gastrointestinal tumors is only approximately 0.5%. Our aim is to describe our experience with this rare disease and to increase knowledge on the diagnosis and treatment of appendiceal malignant tumors. Case presentation: We report the case of a 69-year-old woman who was admitted to the hospital due to dyspepsia. The patient was a carrier of hepatitis B virus, and liver dysfunction was diagnosed preoperatively. Abdominal enhanced computed tomography and colonoscopy showed that the appendix was significantly enlarged and dilated, and effusion and appendicitis were observed. Mucinous adenocarcinoma and appendiceal abscesses were not excluded because of the lack of specificity, which makes it difficult to diagnose the disease before a surgery. Laparoscopic appendectomy was performed, and a rapid frozen pathological examination showed a mucinous tumor of the appendix. Intraperitoneal hyperthermic chemotherapy with cisplatin was administered. The patient had abdominal hemorrhage on the fifth day after the surgery. After active treatment, she was discharged from the hospital 19 days after the surgery.Conclusions: The diagnosis of appendiceal malignant tumors mainly depends on preoperative imaging and microscopic results,and highly suspected patients, rapid pathological examination is needed during the operation., and so on. Notably, for elderly patients with hepatitis B infection and liver dysfunction, there is a probability of postoperative bleeding.
Performance Enhancement of Mini Agri-voltaic System for Roof Top Garden
Authors: Prasad Arani Rajendra , Shankar Ramalingam , Patil Chandrashekhar K , Karthick Alagar , Kumar Amit , Rahim Robbi 
Published: March 2021

Abstract
The Agri-voltaic (AV) is an emerging technology to harness the solar energy. The performance of the AV modules depends on the incident solar radiation, geographical location and the surface temperature of the modules. The performance of the AV system needs to be monitored by manually or embedded controllers. The commercially available technologies for monitoring the system is costlier and need to be optimised. The Arduino controller is used to monitor the performance of the photovoltaic (PV) system in Coimbatore (11.0160 N, 76.95580 E), Tamilnadu, India. The PV surface temperature is monitored and controlled by flowing the water above the module by setting the mean ambient temperature as a reference temperature 34 °C when the system exceeds the reference temperature. PV surface temperature is reduced up to 16°C thus improved the electrical efficiency by 17% compare to the reference module. The Arduino controller control the relay to switch on the motor to control the mass flow rate of the water at 0.0028kg/s. The various parameters are measured such as voltage, current and solar radiation of the location and analysed. The estimated cost of monitoring system and various sensor is 10$ which cost comparatively 50% lower than the other PV monitoring controllers. This method can be employed in the medium and large-scale irrigation system.
Ssrp1 Promotes Lung Cancer Progression By Blocking The Wnt Pathway and Is Negatively Regulated By Mirna-28-5p
Authors: Jia Shengnan , Wang Qian , Jiao Yan , Guo Baofeng , Wang Lihui , Peng Liping , Zhang Ling 
Published: March 2021

Abstract
Background: Structure-specific recognition protein 1 (SSRP1) plays important roles in the development of various tumors. Numerous reports have described the effects of microRNAs (miRNAs) on lung cancer apoptosis, metastasis and proliferation. However, the relationship between SSRP1 and miRNAs in the development of lung cancer remains unclear. Therefore, the purpose of our study was to explore the functions of SSRP1 in the occurrence and development of lung cancer.Methods: First, we analyzed the expression of SSRP1 in human lung cancer tissues and normal tissues, and the relationship between SSRP1 gene expression and overall survival through the UALCAN and GEPIA browsers. Second, we conducted experiments in vivo and vitro to demonstrate the roles and mechanisms of SSRP1 in the occurrence and development of lung cancer and its relationship with miR-28-5p.Results: Our study demonstrated over-expression of SSRP1 in tissue sections from patients with lung cancer and in lung cancer cell lines, as validated by bioinformatics analysis. The over-expression of SSRP1 was found to be associated with lung cancer development and low overall survival rates. Silencing of SSRP1 by siRNA inhibited lung cancer proliferation, migration and invasion by blocking the WNT signaling pathway in vitro and vivo. We also verified SSRP1 was negatively regulated by miR-28-5p，as predicted by a variety of miRNA-related databases. Further studies showed that miR-28-5p mediated suppression of SSRP1 inhibited lung cancer cell proliferation.Conclusion: Therefore, our data suggested that SSRP1 promotes lung cancer progression by blocking the WNT pathway and is negatively regulated by miRNA-28-5p.