bluuebunny/crossref_metadata_2025_split huggingface dataset:
Military Alliances and Public Support for War
Authors: Tomz Michael , Weeks Jessica L P 
Published: February 2021

AbstractHow do military alliances affect public support for war to defend victims of aggression? We offer the first experimental evidence on this fundamental question. Our experiments revealed that alliance commitments greatly increased the American public's willingness to intervene abroad. Alliances shaped public opinion by increasing public fears about the reputational costs of nonintervention and by heightening the perceived moral obligation to intervene out of concerns for fairness and loyalty. Finally, although alliances swayed public opinion across a wide range of circumstances, they made the biggest difference when the costs of intervention were high, the stakes of intervention were low, and the country needing aid was not a democracy. Thus, alliances can create pressure for war even when honoring the commitment would be extremely inconvenient, which could help explain why democratic allies tend to be so reliable. These findings shed new light on the consequences of alliances and other international legal commitments, the role of morality in foreign policy, and ongoing debates about domestic audience costs.
Relationships among intramammary health, udder and teat characteristics, and productivity of extensively managed ewes
Authors: Knuth Ryan M , Stewart Whitney C , Taylor Joshua B , Bisha Bledar , Yeoman Carl J , Van Emon Megan L , Murphy Thomas W 
Published: February 2021

Abstract
Mastitis is an economically important disease and its subclinical state is difficult to diagnose, which makes mitigation more challenging. The objectives of this study were to screen clinically healthy ewes in order to 1) identify cultivable microbial species in milk, 2) evaluate somatic cell count (SCC) thresholds associated with intramammary infection, and 3) estimate relationships between udder and teat morphometric traits, SCC, and ewe productivity. Milk was collected from two flocks in early (&lt;5 d) and peak (30 to 45 d) lactation to quantify SCC (n = 530) and numerate cultivable microbial species by culture-based isolation followed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS; n = 243) identification. Within flock and lactation stage, 11% to 74% (mean = 36%) of samples were culture positive. More than 50 unique identifications were classified by MALDI-TOF MS analysis, and Bacillus licheniformis (18% to 27%), Micrococcus flavus (25%), Bacillus amyloliquefaciens (7% to 18%), and Staphylococcus epidermidis (26%) were among the most common within flock and across lactation stage. Optimum SCC thresholds to identify culture-positive samples ranged from 175 × 103 to 1,675 × 103 cells/mL. Ewe productivity was assessed as total 120-d adjusted litter weight (LW120) and analyzed within flock with breed, parity, year, and the linear covariate of log10 SCC (LSCC) at early or peak lactation. Although dependent on lactation stage and year, each 1-unit increase in LSCC (e.g., an increase in SCC from 100 × 103 to 1,000 × 103 cells/mL) was predicted to decrease LW120 between 9.5 and 16.1 kg when significant. Udder and teat traits included udder circumference, teat length, teat placement, and degree of separation of the udder halves. Correlations between traits were generally low to moderate within and across lactation stage and most were not consistently predictive of ewe LSCC. Overall, the frequencies of bacteria-positive milk samples indicated that subclinical mastitis (SCM) is common in these flocks and can impact ewe productivity. Therefore, future research is warranted to investigate pathways and timing of microbial invasion, genomic regions associated with susceptibility, and husbandry to mitigate the impact of SCM in extensively managed ewes.
Factors associated with facilitating advance care planning based on the theory of planned behaviour
Authors: Takeshita Yae , Kaneko Fumiko , Okamura Hitoshi 
Published: February 2021

Abstract

Background
In Japan, educational support for advance care planning is still limited, and the factors facilitating advance care planning practice have not been identified. The aim of this study is to identify the factors associated with advance care planning practice in Japan using the theory of planned behaviour.

Methods
We conducted a cross-sectional study through a nationwide online questionnaire survey with 446 Japanese residents aged 20 years and older. After categorizing participants into two groups based on who performed advance care planning, comparisons were made (univariate analysis) regarding attitudes towards advance care planning, willingness to perform advance care planning, subjective norms, sense of control in performing advance care planning, presence of and relationship with a family doctor, experience of seeing or using a ventilator, and degree of self-determination (Autonomy Preference Index) as well as sociodemographic data. In addition, a logistic regression analysis was performed using the factors with significant differences in the univariate analysis as independent variables and the existence of the implementation of advance care planning as a dependent variable.

Results
The group with advance care planning consisted of 106 participants (23.8%), and the group without advance care planning comprised 340 participants (76.2%). Through logistic regression analysis, age (odds ratio: 1.020), subjective norms (odds ratio: 3.276) and experience with mechanical ventilation (odds ratio: 1.997) were extracted as significant factors influencing advance care planning implementation.

Conclusions
Advance care planning may be facilitated by providing support not only to the patients but also to their family members to be positively disposed towards advance care planning and by offering comprehensive education regarding using a ventilator.
No Evidence of Competition Between the Blacklegged Tick (Acari: Ixodidae) and American Dog Tick on the Rodent Host White-Footed Deermouse (Rodentia: Cricetidae) in Southwestern Tennessee
Authors: Butler R A , Kennedy M L , Houston A E , Bowers E K , Coons L B , Paulsen D , Trout Fryxell R T 
Published: February 2021

AbstractInvestigations that analyze interspecific associations of vectors on their hosts are important for understanding community structure and implementing ways to comprehend mechanisms of pathogen transmission. We assessed the interspecific association of two tick species (Ixodes scapularis Say (Ixodida: Ixodidae) and Dermacentor variabilis Say (Ixodida: Ixodidae)) on the rodent host Peromyscus leucopus Rafinesque (Rodentia: Cricetidae) at the Hobart Ames Research and Education Center in southwestern Tennessee. Of the rodents captured, 95 (63%) had neither species of tick, 6 (4%) had both tick species, 25 (16%) had I. scapularis only, and 26 (17%) had D. variabilis only. A coefficient of association (C7 = −0.08) was calculated, which suggested there was competition between the two species of ectoparasites, but this value was not significant, indicating that there was a neutral relationship between the tick species on P. leucopus. The co-occurrence of both tick species on their host at the same time suggested that the two tick species can occupy the same host and use the same resources without competing.
Spa Typing of Staphylococcus aureus in a Neonatal Intensive Care Unit During Routine Surveillance
Authors: Grohs Emily , Hill-Ricciuti Alexandra , Kelly Nicole , Messina Maria , Green Daniel A , Geng Wenjing , Annavajhala Medini K , Zachariah Philip , Mathema Barun , Uhlemann Anne-Catrin , Saiman Lisa 
Published: February 2021

Abstract

Background
Staphylococcus aureus protein A (spa) typing can be used to expand characterization of the epidemiology of methicillin-susceptible S. aureus (MSSA) and methicillin-resistant S. aureus (MRSA) in neonatal intensive care units (NICU).

Methods
From January 2017 to June 2018, twice-monthly surveillance for S. aureus was performed in an academically affiliated NICU. Decolonization of infants colonized with S. aureus included chlorhexidine gluconate bathing and/or mupirocin for those with mupirocin-susceptible strains. Spa typing and mupirocin-resistance testing were performed. Demographic and clinical characteristics were compared between infants colonized with MSSA vs MRSA and infants with and without the most common MSSA spa type, MSSA-t279.

Results
Overall, 14% and 2% of 1556 hospitalized infants had positive surveillance cultures for MSSA and MRSA, respectively. Thirty-six infants harbored unique MSSA spa types, 5 infants harbored unique MRSA spa types, and 30 MSSA and 6 MRSA spa types were identified in ≥2 infants. No outbreaks were identified during the study period. MSSA-t279 was isolated from 3% of infants and largely detected from infants hospitalized in one section of the NICU; 96% of t279 isolates were mupirocin resistant. Infection rates, length of hospitalization, and mortality were similar among infants initially colonized with t279 vs other MSSA spa types.

Conclusions
The MSSA colonization burden was 5-fold larger than that of MRSA. Numerous unique spa types were identified. The most common spa type, MSSA-t279, was not associated with increased morbidity or mortality but was mupirocin resistant and associated with clustered NICU beds. This suggests potential transmission from the environment, shared staff, and/or workflow issues requiring further study. Other decolonization strategies for S. aureus in the NICU are needed.
Xanthohumol ameliorates memory impairment and reduces the deposition of β-amyloid in APP/PS1 mice via regulating the mTOR/LC3II and Bax/Bcl-2 signalling pathways
Authors: Sun Xiao-Lei , Zhang Jia-Bao , Guo Yun-Xiang , Xia Tian-Shuang , Xu Ling-Chuan , Rahmand Khalid , Wang Guo-Ping , Li Xiao-Jin , Han Ting , Wang Na-Ni , Xin Hai-Liang 
Published: February 2021

Abstract

Objectives
Xanthohumol (XAN) is a unique component of Humulus lupulus L. and is known for its diverse biological activities. In this study, we investigated whether Xanthohumol could ameliorate memory impairment of APP/PS1 mice, and explored its potential mechanism of action.

Methods
APP/PS1 mice were used for in vivo test and were treated with N-acetylcysteine and Xanthohumol for 2 months. Learning and memory levels were evaluated by the Morris water maze. Inflammatory and oxidative markers in serum and hippocampus and the deposition of Aβ in the hippocampus were determined. Moreover, the expression of autophagy and apoptosis proteins was also evaluated by western blot.

Key findings
Xanthohumol significantly reduced the latency and increased the residence time of mice in the target quadrant. Additionally, Xanthohumol increased superoxide dismutase level and reduced Interleukin-6 and Interleukin-1β levels both in serum and hippocampus. Xanthohumol also significantly reduced Aβ deposition in the hippocampus and activated autophagy and anti-apoptotic signals.

Conclusions
Xanthohumol effectively ameliorates memory impairment of APP/PS1 mice by activating mTOR/LC3 and Bax/Bcl-2 signalling pathways, which provides new insight into the neuroprotective effects of Xanthohumol.
Pitfalls of laparoscopic Re-TAPP in recurrent inguinal hernia repair—a plea for extended preoperative diagnostic
Authors: Raguz Ivana , Burger Reint , Vonlanthen Rene , Bueter Marco , Thalheimer Andreas 
Published: February 2021

Abstract
According to international guidelines, recurrent inguinal hernia should be treated by a surgical approach opposing of the primary strategy (anterior–posterior or posterior–anterior). However, recent evidence demonstrates feasibility and safety of re-laparoscopic repair of recurrent inguinal hernia after primary laparoscopy. For such a strategy, correct identification of anatomical structures is challenging, but absolutely crucial for a satisfactory postoperative result. This case of an unrecognized sliding hernia of the sigmoid colon during re-laparoscopy highlights that a precise physical examination as well as an extended preoperative radiological workup (ultrasound, computed tomography and/or magnetic resonance imaging of the abdomen and pelvis) should be considered prior to re-laparoscopy of recurrent inguinal hernia.
Multigene editing reveals that MtCEP1/2/12 redundantly control lateral root and nodule number in Medicago truncatula
Authors: Zhu Fugui , Ye Qinyi , Chen Hong , Dong Jiangli , Wang Tao 
Published: February 2021

Abstract
The multimember CEP (C-terminally Encoded Peptide) gene family is a complex group that is involved in various physiological activities in plants. Previous studies demonstrated that MtCEP1 and MtCEP7 control lateral root formation or nodulation, but these studies were based only on gain of function or artificial miRNA (amiRNA)/RNAi approaches, never knockout mutants. Moreover, an efficient multigene editing toolkit is not currently available for Medicago truncatula. Our quantitative reverse transcription–PCR data showed that MtCEP1, 2, 4, 5, 6, 7, 8, 9, 12, and 13 were up-regulated under nitrogen starvation conditions and that MtCEP1, 2, 7, 9, and 12 were induced by rhizobial inoculation. Treatment with synthetic MtCEP peptides of MtCEP1, 2, 4, 5, 6, 8, and 12 repressed lateral root emergence and promoted nodulation in the R108 wild type but not in the cra2 mutant. We optimized CRISPR/Cas9 [clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9] genome editing system for M. truncatula, and thus created single mutants of MtCEP1, 2, 4, 6, and 12 and the double mutants Mtcep1/2C and Mtcep5/8C; however, these mutants did not exhibit significant differences from R108. Furthermore, a triple mutant Mtcep1/2/12C and a quintuple mutant Mtcep1/2/5/8/12C were generated and exhibited more lateral roots and fewer nodules than R108. Overall, MtCEP1, 2, and 12 were confirmed to be redundantly important in the control of lateral root number and nodulation. Moreover, the CRISPR/Cas9-based multigene editing protocol provides an additional tool for research on the model legume M. truncatula, which is highly efficient at multigene mutant generation.
Digital humanities and digital social reading
Authors: Rebora Simone , Boot Peter , Pianzola Federico , Gasser Brigitte , Herrmann J Berenike , Kraxenberger Maria , Kuijpers Moniek M , Lauer Gerhard , Lendvai Piroska , Messerli Thomas C , Sorrentino Pasqualina 
Published: February 2021

AbstractProminent among the social developments that the web 2.0 has facilitated is digital social reading (DSR): on many platforms there are functionalities for creating book reviews, ‘inline’ commenting on book texts, online story writing (often in the form of fanfiction), informal book discussions, book vlogs, and more. In this article, we argue that DSR offers unique possibilities for research into literature, reading, the impact of reading and literary communication. We also claim that in this context computational tools are especially relevant, making DSR a field particularly suitable for the application of Digital Humanities methods. We draw up an initial categorization of research aspects of DSR and briefly examine literature for each category. We distinguish between studies on DSR that use it as a lens to study wider processes of literary exchange as opposed to studies for which the DSR culture is a phenomenon interesting in its own right. Via seven examples of DSR research, we discuss the chosen approaches and their connection to research questions in literary studies.
Mt. Everest—we are going to lose many: a survey of fingerprint examiners’ attitudes towards probabilistic reporting
Authors: Swofford H , Cole S , King V 
Published: February 2021

AbstractOver the past decade, with increasing scientific scrutiny on forensic reporting practices, there have been several efforts to introduce statistical thinking and probabilistic reasoning into forensic practice. These efforts have been met with mixed reactions—a common one being scepticism, or downright hostility, towards this objective. For probabilistic reasoning to be adopted in forensic practice, more than statistical knowledge will be necessary. Social scientific knowledge will be critical to effectively understand the sources of concern and barriers to implementation. This study reports the findings of a survey of forensic fingerprint examiners about reporting practices across the discipline and practitioners’ attitudes and characterizations of probabilistic reporting. Overall, despite its adoption by a small number of practitioners, community-wide adoption of probabilistic reporting in the friction ridge discipline faces challenges. We found that almost no respondents currently report probabilistically. Perhaps more surprisingly, most respondents who claimed to report probabilistically, in fact, do not. Furthermore, we found that two-thirds of respondents perceive probabilistic reporting as ‘inappropriate’—their most common concern being that defence attorneys would take advantage of uncertainty or that probabilistic reports would mislead, or be misunderstood by, other criminal justice system actors. If probabilistic reporting is to be adopted, much work is still needed to better educate practitioners on the importance and utility of probabilistic reasoning in order to facilitate a path towards improved reporting practices.
First report and molecular prevalence of potential zoonoticEnterocytozoon bieneusiin Turkish tumbler pigeons (Columba livia domestica)
Authors: Pekmezci Didem , Yetismis Gamze , Colak Zeynep Nurselin , Duzlu Onder , Ozkilic Gamze Nur , Inci Abdullah , Pekmezci Gokmen Zafer , Yildirim Alparslan 
Published: February 2021

AbstractA total of 250 droppings of tumbler pigeons (Columba livia domestica, Columbidae) were collected individually from different breeders in Turkey, to investigate the presence and genotyping of microsporidian species by nested PCR and to reveal their zoonotic potential. In the present study, Enterocytozoon bieneusi was the only microsporidian species identified in 35 pigeons with an overall molecular prevalence of 14.0%. Only one known genotype zoonotic Peru6 was identified in all positive samples according to the sequence analyses of the internal transcribed spacer region of ribosomal DNA of E. bieneusi. This study represents the first report of E. bieneusi in pigeons in Turkey. Our study also confirms the competence of breeding pigeons as hosts for the zoonotic Peru6 genotype, corroborating its potential role as a source of human infection and environmental contamination.Lay summaryMicrosporidia are spore-producing fungi defined as emerging opportunistic pathogens of humans. The occurrence of microsporidia in animals could be risky for human public health. Home kept breeding pigeons pose a high risk for transmission of the microsporidians to humans.
Detection of spectral variations of Anomalous Microwave Emission with QUIJOTE and C-BASS
Authors: Cepeda-Arroita R , Harper S E , Dickinson C , Rubiño-Martín J A , Génova-Santos R T , Taylor Angela C , Pearson T J , Ashdown M , Barr A , Barreiro R B , Casaponsa B , Casas F J , Chiang H C , Fernandez-Cobos R , Grumitt R D P , Guidi F , Heilgendorff H M , Herranz D , Jew L R P , Jonas J L , Jones Michael E , Lasenby A , Leech J , Leahy J P , Martínez-González E , Peel M W , Piccirillo L , Poidevin F , Readhead A C S , Rebolo R , Ruiz-Granados B , Sievers J , Vansyngel F , Vielva P , Watson R A 
Published: February 2021

ABSTRACT
Anomalous Microwave Emission (AME) is a significant component of Galactic diffuse emission in the frequency range 10–$60\, \mathrm{GHz}$ and a new window into the properties of sub-nanometre-sized grains in the interstellar medium. We investigate the morphology of AME in the ≈10○ diameter λ Orionis ring by combining intensity data from the QUIJOTE experiment at 11, 13, 17, and $19\, \mathrm{GHz}$ and the C-Band All Sky Survey (C-BASS) at $4.76\, \mathrm{GHz}$, together with 19 ancillary data sets between 1.42 and $3000\, \mathrm{GHz}$. Maps of physical parameters at 1○ resolution are produced through Markov chain Monte Carlo (MCMC) fits of spectral energy distributions (SEDs), approximating the AME component with a lognormal distribution. AME is detected in excess of $20\, \sigma$ at degree-scales around the entirety of the ring along photodissociation regions (PDRs), with three primary bright regions containing dark clouds. A radial decrease is observed in the AME peak frequency from $\approx 35\, \mathrm{GHz}$ near the free–free region to $\approx 21\, \mathrm{GHz}$ in the outer regions of the ring, which is the first detection of AME spectral variations across a single region. A strong correlation between AME peak frequency, emission measure and dust temperature is an indication for the dependence of the AME peak frequency on the local radiation field. The AME amplitude normalized by the optical depth is also strongly correlated with the radiation field, giving an overall picture consistent with spinning dust where the local radiation field plays a key role.
Photometry and polarimetry of comet 46P/Wirtanen in the 2018 apparition
Authors: Rosenbush Vera , Kiselev Nikolai , Husárik Marek , Ivanova Oleksandra , Luk'yanyk Igor , Kleshchonok Valerii , Tomko Dušan , Kaňuchová Zuzana , Pit Nikolai , Antoniuk Кirill , Karpov Nikolai , Savushkin Alexander , Zhuzhulina Elena 
Published: February 2021

Abstract
Extensive photometric and polarimetric observations of comet 46P/Wirtanen within the framework of the international 4*P Coma Morphology Campaign were conducted from August 16, 2018 to February 13, 2019 using five telescopes. Digital processing applied to the direct images of the comet revealed the coma and tail, which varied in shape and size. The jet at the position angle 133.5° was found in the images obtained on December 7 and 9, 2018 in the V and R filters. From modelling the formation of the jet, we calculated the coordinates of the north pole of the nucleus rotation axis, α = 220° ± 10°, δ = –20° ± 8°, and the cometocentric latitude of the active area on the nucleus L = 20° ± 6°. The velocity of matter outflow from this active area was estimated to be 0.5 ± 0.05km/ s. The dust production Afρ changed from 12 to 88cm. During our observation period, the coma colour varied from 0.76m to 0.87m and from 0.38m to 0.50m and the reflectivity gradient from 11 to 16.2 per cent per 1000Å and 5.8 to 15.4 per cent per 1000Å for the B–V and V–R spectral bands, respectively. The comparison of the dust production rate of comet 46P/Wirtanen until 2018 and our data for 2018 apparition confirmed its great decrease. The degree of polarization of comet 46P was measured at the phase angles from 27° to 37°. In order to reliably retrieve the polarimetric class of comet 46P, observations at large phase angles are required.