bluuebunny/crossref_metadata_2025_split huggingface dataset:
Algorithm for controlling the process of buffer wastewater neutralization
Authors: Zhuchenko Anatolii , Osipa Ruslan , Osipa Liudmyla , Ladieva Lesia 
Published: October 2021

In Ukraine, the condition of surface water near industrial enterprises is extremely critical. The operation of enterprises leads to intensive water pollution with industrial and domestic wastewater. Therefore, improving the quality of treatment facilities through the introduction of automated control systems is an urgent problem.
For the operation of automated control systems for typical cleaning processes, a software package is required, which is developed on the basis of appropriate algorithmic software and mathematical models of processes. To obtain them, methods of mathematical and simulation modeling and block diagram method of algorithmization were used.
In order to assess the quality of the developed algorithm for controlling the process of buffer wastewater neutralization during operation, a comparison of control system operation based on this algorithm with the most successful foreign variants of neutralization control systems was made. Simulation for the average values of operating parameters Q = 75 m3 / h, CP = 75 g / l, and Ck = 2 g / l at minimum b = 0.02 g / l pH and maximum buffer value b = 0.47 g / l pH, and also with unidirectional extreme combination of parameters Q = 50 m3 / h, CP = 100 g / l, b = 0,02 g / l pH and Q = 100 m3 / h, CP= 50 g / l, for minimum b = 0.02 g / l pH and maximum buffering value b = 0.47 g / l pH shows that the best quality of transient processes is for the control system operating on the basis of the developed algorithm. For any combination of parameters, the transients for this control system provide better quality transients. Studies have shown that the control system based on the developed algorithm in comparison with the previously proposed systems provides better process control by reducing the time of transients and reducing the dynamic deviation of the output parameters, which improves the quality of wastewater treatment.
Given the non-stationary process and high requirements for the cleaning parameters, manual control of this process is beyond the power of even an experienced operator. The developed mathematical model describing the dynamics of the wastewater neutralization reactor with buffer properties and the process control algorithm made it possible to proceed to the development of the control system software, which is necessary for the automated control of this process.
The Effect of Magnetite Nanoparticles on the Growth and Development of Nicotiana Tabacum Plants in Vivo and in Vitro Culture
Authors: Gorobets Svitlana , Ilchuk Nina , Demianenko Iryna , Bannikova Maria 
Published: October 2021

Background. Nanomaterials are easily modified and have unique characteristics associated with a large reactive surface Due to these properties, nanomaterials are used in various branches of sciences and technology, such as pharmaceuticals, biotechnology, chemical technology, etc. Recently, the effect of magnetite nanoparticles on the morphological properties of plants has been actively studied for their further use as nanoadditives to increase yields and improve the properties of agricultural plants. Tobacco (Nicotiana tabacum) is a model object of plant biotechnology, it is used to study the effect of various factors on dicotyledonous plants, so it was chosen to study the effect of magnetite on the growth, development, and mass accumulation by plants.
Objective. We are aimed to study the effect of magnetite nanoparticles on the growth and development of Nicotiana tabacum in vivo and in vitro.
Methods. The ability of tobacco to produce biogenic magnetic nanoparticles by searching for mammal proteins homologues in theNicotiana tabacum proteome using the Blast NCBI program was studied using comparative genomics methods. The plants were divided into groups (control, magnetite nanoparticle concentration 0.1 mg/cm3, magnetite nanoparticle concentration 1 mg/cm3) for both in vivo and in vitro experiments. Analysis of plant parameters was performed every 14 days to study the dynamics of the effects of magnetite nanoparticles.
Results. It was determined that magnetite nanoparticles at a concentration of 0.1 mg/cm3 in culture in vitro and in vivo significantly affect the growth of the root system and sprouts of Nicotiana tabacum. On the 56th day of plant cultivation in vitro on a salivary medium supplemented with magnetite nanoparticles at a concentration of 0.1 mg/cm3, an increase in the shoot length by 13.3%, root length by 31.7%, and the mass of absolutely dry substances by 18.75% was observed compared to the control. Treatment of magnetite nanoparticles with a suspension at a concentration of 0.1 mg/cm3 led to more pronounced results when growing tobacco in vivo. So, on the56th day, the root length increased by 23.3%, the length of the shoot – by 19.2%, and the mass of absolutely dry substances – by2 times, the first leaves appeared 2 days earlier compared to the control. The addition of magnetite nanoparticles to the substrate on which the plants were grown in vivo at a concentration of 1 mg/cm3 inhibits the growth of tobacco.
Conclusions. Studies have shown the expediency of using magnetic nanoparticles at a concentration of 0.1 mg/cm3 as nanofertilizers in tobacco cultivation.
2001-2021, duas décadas da Brigada Nacional de Teatro do MST Patativa do Assaré: ressonâncias, desafios e interfaces com o trabalho teatral da Educação do Campo
Authors: Villas-Boas Rafael Litvin 
Published: October 2021

O artigo analisa a experiência de duas décadas de atuação da Brigada Nacional de Teatro do MST em comunidades camponesas de diversos estados brasileiros, por meio das metodologias da observação participante, da revisão bibliográfica e da pesquisa qualitativa O trabalho evidencia as tradições do teatro político e popular que ensejam a experiência teatral do MST. Um dos resultados da pesquisa é destacar que a peculiar dinâmica de produção e circulação da Brigada teve desdobramentos em universidades públicas, nas Licenciaturas em Educação do Campo, demonstrando o potencial de construção de uma cultura política contra-hegemônica.
Palavras-chave: teatro do oprimido, MST, cultura política, educação do campo.

2001-2021, two decades of the National Theater Brigade of the MST Patativa do Assaré: resonances, challenges and interfaces with the theatrical work of Rural Education
ABSTRACT. The article analyzes the experience of two decades of work by the MST National Theater Brigade in peasant communities in several Brazilian states, through the methodologies of participant observation, literature review and qualitative research. The work highlights the traditions of popular and political theater that give rise to the theatrical experience of the MST. One of the results of the research is to highlight that the peculiar dynamics of production and circulation of the Brigade had consequences in public universities, in the Degrees in Rural Education, demonstrating the potential for building a counter-hegemonic political culture.
Keywords: theater of the oppressed, MST, political culture, rural education.

2001-2021, dos décadas de la Brigada Nacional de Teatro del MST Patativa do Assaré: resonancias, desafíos e interfaces con el trabajo teatral de Educación del Campo
RESUMEN. El artículo analiza la experiencia de dos décadas de trabajo de la Brigada Nacional de Teatro MST en comunidades campesinas de varios estados brasileños, a través de las metodologías de observación participante, revisión de literatura e investigación cualitativa. El trabajo destaca las tradiciones del teatro popular y político que dan origen a la experiencia teatral del MST. Uno de los resultados de la investigación es resaltar que la peculiar dinámica de producción y circulación de la Brigada tuvo consecuencias en las universidades públicas, en los Grados en Educación Rural, demostrando el potencial para construir una cultura política contra hegemónica.
Palabras clave: teatro del oprimido, MST, cultura política, educación del campo.
Análise comparativa da eficiência alocativa das despesas públicas municipais utilizando mineração de dados
Authors: Guelman Davis Paula , De Souza Antônio Artur 
Published: October 2021

Objetivo da pesquisa: Analisar, comparativamente, a eficiência alocativa das despesas públicas dos municípios brasileiros utilizando técnicas de mineração de dados. Entende-se, como eficiente, a melhor relação entre o volume de despesas e resultados nos indicadores socioeconômicos, ou seja, menores despesas e melhores resultados quando comparado aos outros municípios.
Enquadramento teórico: Teorias da Federação, especificamente o Federalismo Fiscal, na qual uma das principais proposições é a de que tributos e despesas publicas descentralizadas são mais eficientes.
Metodologia: Coleta e a integração de dados financeiros e operacionais. Transformação em indicadores. Limpeza e seleção de indicadores para transformação em atributos categóricos (discretização). Geração de árvores de decisão, a partir de algoritmos de mineração de dados, permitindo identificar características em comum dos municípios com desempenho destacado.
Resultados: Viabilidade e importância do uso da mineração de dados sobre conjuntos abrangentes de dados. Foram identificados padrões relevantes nas áreas de educação, saúde e desenvolvimento, como a importância de se despender recursos na formação dos docentes, e caracterizadas discrepâncias regionais em termos do desempenho do Sistema Único de Saúde (SUS).
Originalidade: Nos estudos anteriores, foi possível constatar uma repetição da metodologia Data Envelopment Analysis (DEA) para estudo da eficiência das despesas públicas. Em contraste com esses estudos, utilizamos grandes conjuntos de dados municipais, de múltiplas fontes e áreas, aplicando técnicas de mineração de dados para encontrar padrões relevantes.
Contribuições teóricas e práticas: Proposição de uma metodologia de estudo da eficiência da despesa pública municipal, válida do ponto de vista teórico e prático, em múltiplas áreas de atuação, com as técnicas e ferramentas da Mineração de Dados.
Implementing Specialized Vestibular Physiotherapy in An Emergency Department: A Process Evaluation
Authors: Ip Kelvin , Lloyd Melanie , Luscombe Allison , Hitch Danielle 
Published: October 2021

Abstract
Background: Dizziness and vertigo-like symptoms, often caused by common peripheral vestibular disorders such as Benign Paroxysmal Positional Vertigo (BPPV), may have a significant detrimental impact on function and quality of life. The impact of these symptoms often result in Emergency Department (ED) presentations. Evidence based clinical practice guidelines strongly recommend the use of physical assessment and treatment maneuvers for the assessment, diagnosis and treatment of these symptoms. The aim of this study was to evaluate the process of implementing specialized vestibular physiotherapy in an emergency department, from the clinician perspective.Methods: This implementation study utilized a retrospective mixed methods process evaluation to understand how specialized vestibular physiotherapy operated in an Australian emergency department. The PARiHS Framework was embedded within the methodology and analytical approach of the study, to ensure a comprehensive approach which was closely aligned to implementation science. Nine clinicians retrospectively completed the Organizational Readiness for Change Assessment (ORCA), Acceptability of Intervention Measure (AIM), Intervention Appropriateness Measure (IAM) and Feasibility of Intervention Measure (FIM). Seven clinicians also participate in a focus group or interview.Results: A range of barriers and facilitators to the implementation process were identified by participants, some of which spanned multiple domains of the PARiHS framework. Relationships with service leaders, champions and medical staff were found to be a key facilitator to implementation, along with a generally held perception that specialized vestibular physiotherapy was acceptable and feasible. The main barrier identified was a lack of capacity to deliver and support this innovation, both within the physiotherapy workforce and the broader multidisciplinary team.Conclusions: This study demonstrates the process of implementation of a specialized vestibular physiotherapy team in an ED setting was generally well received by clinicians, but also involved some challenges and barriers. Services looking to implement specialized vestibular physiotherapy in the ED may refer to the recommendations arising from the findings of this study to guide their approach to innovation.
Intact Predictive Motor Sequence Learning in Autism Spectrum Disorder
Authors: Rybicki Alicia J. , Galea J. M. , Schuster Bianca , Hiles C. , Fabian C. , Cook J. L. 
Published: October 2021

Abstract
Background. Atypical motor learning has been suggested to underpin the development of motoric challenges (e.g., handwriting difficulties) in autism. Bayesian accounts of autistic cognition propose a mechanistic explanation for differences in the learning process in autism. Specifically, that autistic individuals overweight incoming, at the expense of prior, information and are thus less likely to a) build stable expectations of upcoming events and b) react to statistically surprising events. Although Bayesian accounts have been suggested to explain differences in learning across a range of domains, to date, such accounts have not been extended to motor learning.Methods. 28 autistic and 35 non-autistic controls (IQ > 70) completed a computerised task in which they learned sequences of actions. On occasional “surprising” trials, an expected action had to be replaced with an unexpected action. Sequence learning was indexed as the reaction time difference between blocks which featured a predictable sequence and those that did not. Surprise-related slowing was indexed as the reaction time difference between surprising and unsurprising trials.Results. No differences in sequence-learning or surprise-related slowing were observed between the groups. Bayesian statistics provided anecdotal to moderate evidence to support the conclusion that sequence learning and surprise-related slowing were comparable between the two groups. Conclusions. We conclude that individuals with autism do not show atypicalities in response to surprising events in the context of motor sequence-learning. These data demand careful consideration of the way in which Bayesian accounts of autism can (and cannot) be extended to the domain of motor learning.
Classification of Hypertensive and Normotensive Subjects Using Bilateral Differential Biopotential Signals
Authors: Sarkar Arindam , Goswami Bhaswati , Ghosh Ratna 
Published: October 2021

Abstract
Hypertension or high blood pressure is a severe health issue in the modern world, especially in this pandemic scenario, that can cause many heart related diseases or even death, and it is increasing day by day. For this reason, a
reliable, automatic and easy to use system for hypertensive subject detection is an important focus for the researchers. Biopotential signals can play a pivotal role in this regard. Though, few strategies were proposed based on electrocardiogram (ECG) or electrodermal (EDA) signals, but those require special circuitry, as well as trained persons. In this article, a method is proposed to classify hypertensive and normotensive subjects using differential biopotential
signals. Neither special circuitry, nor much expertise is required for handling this system. It was assumed that progression of rest is dependent upon blood pressure. To serve the purpose, signals were acquired from both hypertensive and normotensive subjects bilaterally for 10 continuous minutes. Result of the random forest (RF) classification establishes that from the analysis of the progression of the bilaterally acquired differential biopotential signals, hypertensive subjects can be distinguished from normotensive subjects.
Optimization of an Economical Medium Composition For The Coculture of Clostridium Butyricum And Bacillus Coagulans
Authors: Li Yonghong , Wang Yun , Liu Yingying , Li Xuan , Li Keke , Feng Lifei 
Published: October 2021

Abstract
Clostridium butyricum is a spore-forming probiotic existing in the intestines of humans and animals which can promote the enhancement of beneficial bacteria and maintain intestinal microecological balance. However, it is difficult to improve the production level of C. butyricum by conventional fermentation process. In this study, a co-fermentation process of C. butyricum DL-1 and Bacillus coagulans ZC2-1 was established to improve the viable counts and spore yield of C. butyricum, and the formula of coculture medium was optimized by flask fermentation. The results showed that the optimum medium composition is bran 10 g/L, corn steep powder 15 g/L, peptone 15 g/L, K2HPO4 1 g/L and MnSO4 0.5 g/L. Cultured stationarily in the optimal medium for 36 h, the number of viable bacteria of C. butyricum DL-1 reached 1.5×108 CFU/mL and the spore forming rate was 92.6%. The results revealed an economical and effective medium composition for the coculture of C. butyricum and B. coagulans. The co-fermentation process established in this study provides a new fermentation mode for the industrial production of other absolute anerobic bacteria.
The effectiveness of oral immunotherapy in patients with Sesame anaphylaxis using Omalizumab
Authors: Salari Fereshteh , Bemanian Mohammad Hassan , Fallahpour Morteza , Mahdaviani Seyed Alireza , Shokri Sima , Khoshmirsafa Majid , Seif Farhad , Nabavi Mohammad , Arshi Saba 
Published: October 2021

Abstract
Objective

Sesame allergy is the most prevalent allergy to seeds. Oral immunotherapy (OIT) is defined as continuous consumption of an allergen at special doses and time. Omalizumab (Anti-IgE) increases tolerance to allergens used in OIT. This study evaluated the effectiveness of a new sesame OIT protocol in patients with sesame anaphylaxis in combination with omalizumab.
Methods

In this prospective open-label interventional trial study, 11 patients with a history of sesame anaphylaxis were enrolled after approval by Oral Food Challenge (OFC) test. At baseline, skin prick test (SPT) and skin prick to prick (SPP) test were performed. Serum sesame-specific IgE (sIgE) levels were measured. The maintenance phase was continued at home with daily sesame intake for 4 months. At the end of month 4, the OFC and above-mentioned tests were repeated to evaluate the treatment effectiveness.
Results

All 11 patients who underwent sesame OIT after 4 months could tolerate a dietary challenge of 22 ml tahini (natural sesame seed, equal to 5,000 mg of sesame protein and higher) and the average of wheal diameter in the SPT and SPP tests significantly decreased after desensitization.
Conclusion

This OIT protocol may be a promising desensitization strategy for patients with sesame anaphylaxis. Also, omalizumab obviously reduced the severity of reactions.
Robot-assisted Anterior Odontoid Screw for the Treatment of Type Ⅱ Odontoid Fractures: Safety and Effectiveness Analysis
Authors: Zhao Songchuan , Bo Yang , Du Jinpeng , Yan Liang , Hao Dingjun , Wang Haosheng , Wei Jianmin , Gao Lin 
Published: October 2021

Abstract
Background: Anterior odontoid screw fixation is considered to be preferred surgical treatment for the type Ⅱ odontoid fractures. However, due to the high difficulty to insert odontoid screw with barehand, the high risk of screw misalignment and damage to surrounding important tissue structures, we urgently need robot-assisted screw insert navigation technology to improve the safety and accuracy of inserting odontoid screws.Methods: We retrospectively analyzed 7 patients with type II odontoid fractures who underwent Tinavi robot-assisted screw insert technology from May 2018 to May 2019 at our hospital. All patients had received 64-row CT scans and 3D reconstructions completed preoperatively, and magnetic resonance (MRI) were performed to verify the severity of odontoid fractures, soft tissue injuries and vertebral artery height. Postoperative CT was repeated in 6 months after surgery to evaluate cervical stability and confirm whether the screw had breached the bone cortex, the accuracy of screw placement based on Rampersaud A-D grade. Functional recovery was assessed using the post-traumatic Mayor scoring system for the cervical spine.Results: All 7 patients successfully completed the robot-assisted operation without nerve and blood vessel damage. What is the operation time 103.3 minutes, intraoperative blood loss 11.1 ml. The angulation and displacement of the fracture were basically corrected by closed reduction during the operation. Postoperative CT of these 7 patients showed that the cervical spine was stable, the accuracy of “perfect” and “clinically acceptable” odontoid screw implantation was 100% (7/7), none of the seven odontoid screws breached the bone cortex. Reexamination of X-rays showed that the fractures were all healed, and the average fracture healing time was average 13.7weeks (12-15weeks). During the follow-up period, 7 patients had no surgical complications, postoperative cervical spine trauma mayo score: excellent in 6 cases and good in 1 case. Conclusion: Tinavi robot-assisted screw insert technology is a minimally invasive, accurate, safe and feasible method for the treatment of type Ⅱ odontoid fractures.
FOXA3: A Novel Tumor Suppressor in Esophageal Squamous Cell Carcinoma
Authors: Zhang Siang , Jin Yuxiang , Han Qianyu , Zhao Xuewei , Xue Lei 
Published: October 2021

Abstract
Background: Forkhead box A(FOXA) family, have been widely investigated in cancer research. However, currently the study of FOXA3 in malignant tumors is still limited compared with other family members. FOXA1 and FOXA2 both play a role in the development and progression of esophageal cancer and Barrett's esophagus, but the exact role of FOXA3 in esophageal squamous cell carcinoma (ESCC) has not been elucidated.Methods: The expression of FOXA3 in ESCC tissues was determined by real-time PCR immunohistochemistry staining. The relationship between FOXA3 and overall survival rate of patients was analyzed by Kaplan-Meier analysis, and Cox regression analysis was used to analyze independent prognostic risk factors. Cell proliferation was analyzed by CCK-8 assay, EdU assay and colony forming assay. Cell migration was analyzed by wound healing assay and Transwell assay. Tumorigenesis by subcutaneous injection was performed to detect the inhibition of tumors by FOXA3 in vivo.Results: We found that FOXA3 is down-regulated in ESCC tissues and low FOXA3 expression significantly correlated with a poor prognosis of ESCC. Additionally, after up-regulating the FOXA3 expression, the abilities of proliferation, migration and invasion in ESCC cells were significantly inhibited. Moreover, over-expression of FOXA3 can inhibit tumor growth in vivo either via tumorigenesis assay by subcutaneous injection.Conclusions: Low FOXA3 expression significantly correlated with a poor prognosis of ESCC and the over-expression of FOXA3 could inhibit the growth and metastasis of ESCC, which indicated that FOXA3 maybe a novel biomarker and therapeutic target for ESCC.