bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of box section coverage on the hydraulic parameters of open channels
Authors: Osman Emam A. , Taha Zahraa 
Published: October 2021

Abstract
The effects of box coverage blockage on the hydraulic characteristics of open channels within the case of sub-critical flow in the open channel were explored experimentally in research. Fifty-two test runs were utilized to attain the research's objectives, with four water discharges of 2, 5, 8, and 11 L/sec, three-box coverage side dimensions of 8.8, 10.4, and 12.90 cm, and four coverage blockage ratios of 0, 10, 20, and 30%. The water depth and velocity were measured in each run. The results revealed that increasing the blockage ratios, water discharge, and a diminishing within the area passing water through the coverage led to an increment of the heading up, head losses, and water surface level. The worst-case situation was a little coverage dimension (8.80 cm side) with 30% blockage and discharge of 11 L/s. Within blockage ratios, of 0, 10, 20, and 30% and discharge 11 L/s, the relative heading up ratio (hRu%) values were 85, 97, 111, and 125 percent respectively, and for the relative head losses ratio values downstream the coverages (hRloss%) were 88, 99, 113, and 131 percent respectively related to the depth of a non-coverage case. The flow velocities and the relative area passing water through the coverage were the most effective variables on heading up and head losses. The relative heading up and the relative head loss increased with the increment of the Froude number (Frd). Within a constant relative wetted area of coverage (Ar), and increasing the Froude number (Frd) by 0.01 percent, the relative heading up and relative head loss approximately increased by 5.5% and 6.2% respectively. It is recommended to implement the periodic maintenance of the coverage to improve the discharge capacity of the open channel.
Shaping a baseflow model through multiple regression analysis: the Çoruh watershed example
Authors: Şenocak Serkan , Taşci Sait 
Published: October 2021

Abstract
In today's conditions, where the frequency of events related to global climate change is increasing, it is important to employ water science to utilize water with maximum efficiency and to keep water under control in the areas close to its consumption zone. It is also important to determine how much of the flow in the stream during dry periods is the baseflow and how much of it is direct flow. This study designed a model of the baseflow index (BFI) and the baseflow rate (Qb) in one of the watersheds in Turkey. The smoothed minima method designed by the United Kingdom Institute of Hydrology (UKIH) was used to calculate the BFI and Qb at 10 flow observation stations in the Çoruh watershed. The Çoruh Watershed Baseflow Model was designed using BFI and Qb values with watershed characteristics and other variables. The determination coefficient of the BFI model was calculated as R² = 0.842, and the Qb model determination coefficient was calculated as R² = 0.99. The usability of the Çoruh model was proven by using the UKIH's smoothed minima method and comparing its relative errors with the BFI and Qb in the Çoruh model.
Determinants of geographical inequalities in domestic water supply across city of Pune, India
Authors: Tholiya Jyoti Jain , Chaudhary Navendu , Alam Bhuiyan Monwar 
Published: October 2021

Abstract
The water supply system in the city of Pune is affected due to the fast and chaotic development in and around the city. The quantity of per capita water supply and hours of supply per day varies substantially across the city. Some central parts of the city benefit from a large availability of water as compared to peripheral areas. This research employed Ordinary Least Squares (OLS) Regression, Geographically Weighted Regression (GWR), and the new version of GWR termed Multi-scale Geographically Weighted Regression (MGWR) models to better understand the factors behind observed spatial patterns of water supply distribution and to predict water supply in newly merged and proposed villages in the Pune city's periphery. Results showed statistical significance of slope; distance from service reservoirs; and water supply hour. MGWR and GWR models improved our results (adjusted R2: 0.916 and 0.710 respectively) significantly over those of the OLS model (adjusted R2: 0.252) and proved how local conditions influence variables. The maps of GWR display how a particular variable is highly important in some areas but less important in other parts of the city. The results from the current study can help decision-makers to make appropriate decisions for future planning to achieve Sustainable Development Goal number 6 (SDG #6), which focuses on achieving universal and equitable access to safe and affordable drinking water for all.
THE EFFECT OF DANCE ON GIRLS' MOTOR ABILITIES
Authors: Uspuriene Aiste Barbora , Svipaite Julija 
Published: October 2021

It is often forgotten that the health of the body, the ability to overcome stress and weakness depend on a person's physical activity and movement. Movement is an inexhaustible means of self-expression, self-realization and cognition of the surrounding world. Research aim – to analyze the literature and to reveal aspects of the effect of dance on girls’ motor abilities.
Design, Synthesis and Bioactivity Evaluation of Novel Chalcone Derivatives
Possessing Tryptophan Moiety with Dual Activities of Anti-Cancer and Partially
Restoring the Proliferation of Normal Kidney Cells Pre-Treated with Cisplatin
Authors: Yao Risheng , He Meng , Yu Mingjun , Li Chao , Meng Xiaoming , Su Jiamin , Zhu Yuting 
Published: October 2021

Background:
Chalcone is a broad-spectrum natural product with anti-cancer and anti-inflammatory activities.
However, low potency, low selectivity, and serious side effects limit its druggability. L-Tryptophan is an essential
precursor molecule of an anti-cancer active substance. Also, the indole moiety inhibits the proliferation of tumor cells
by binding to colchicine sites. A decrease in kidney cell activity caused by kidney inflammation is the primary side
effect of cancer therapy.

Objective:
The purpose of this work was to design, synthesize, and perform bioactivity evaluation of novel chalcone
derivatives possessing tryptophan moiety with dual activities of anti-cancer and partially restoring the proliferation of
normal kidney cells pre-treated with cisplatin.

Methods:
A series of novel chalcone derivatives possessing tryptophan moiety (5a-5g, 6a-6o) were designed, synthesized,
and evaluated for anti-cancer activity against four cancer cell lines (gastric (HGC-27), colon (HCT-116), prostate
(PC-3), and lung (A549)), and a human normal cell line (gastric mucosal epithelial (GES-1)). The activity of restoring
the proliferation of normal kidney cells pre-treated with cisplatin was evaluated by MTT assay. Cell cycle, apoptosis,
and apoptosis proteins (Bax and Bcl-2) were used to evaluate the anti-cancer mechanism of the most potent compound.
Moreover, a docking study was performed to explain the high anti-cancer activity of 6n. The expressions of TNF-α, IL-
6, and MCP-1 were detected by ELISA.

Results:
Most of the compounds exhibited high anti-cancer activity against the HGC-27 cell line and exhibited low
toxicity against the normal cell line. Based on three rounds of a structure optimization, 6n was discovered as the most
potent compound against HGC-27 cells with an IC50 value of 2.02 μM and an SI value of 28.47. Further studies
demonstrated that 6n could induce cell cycle arrest at the G2/M phase and the apoptosis of the HGC-27 cell line by
reducing the expression of Bcl-2 and improving the expression level of Bax. Molecular docking result displayed 6n
bound to the colchicine site. At the same time, 6n also exhibited moderate activity of restoring the proliferation of
normal kidney cells pre-treated with cisplatin by reducing the expression of inflammatory substances.

Conclusion:
Our findings collectively suggested that 6n should be further studied as a potential anti-cancer agent that
could partially restore the proliferation of normal kidney cells pre-treated with cisplatin in gastric cancer patients by an
anti-inflammatory pathway.
Clinical safety of ibuprofen in pediatric practice
Authors: Borysova T.P. 
Published: October 2021

The article presents a review of the literature on the side effects of ibuprofen in children. The international guidelines recommend ibuprofen as an antipyretic and analgesic drug in pediatrics. The drug is characterized by a high profile of efficacy and safety in the treatment of children with fever, mild to moderate pain. Ibuprofen in over-the-counter doses has a low probability of serious side effects from the gastrointestinal tract and kidneys. Side effects of ibuprofen are transient and resolve after discontinuation of treatment. Circumstances associated with a higher risk of adverse events are highlighted. The use of ibuprofen is contraindicated in children with dehydration, which is associated with a risk of acute kidney damage. Caution should be exercised when prescribing ibuprofen to children with community-acquired pneumonia due to the risk of purulent complications. Ibuprofen should not be prescribed to patients with chickenpox to avoid bacterial superinfections. Ibuprofen should be used with caution in children with diseases of the gastrointestinal tract, liver, renal failure, hemorrhagic syndrome, anticoagulant therapy. Ibuprofen is allowed in children with bronchial asthma unless a personal or family history of aspirin-induced asthma. Caution should be exercised when treating premature infants or low birth weight infants due to the reduction in nephron mass and, therefore, the increased risk of renal damage. Ibuprofen should not be used in patients who are sensitive to this drug or other non-steroidal anti-inflammatory drugs. Ibuprofen should be taken in the minimum effective dose and discontinued as soon as possible — no more than 3 days for fever and 5 days for pain.
A Computer Model of the Spread of the Pandemic and its Analysis
Authors: Bardavelidze Avtandil , Basheleishvili Irakli , Bradvelidze Khatuna 
Published: October 2021

The paper describes and analyzes a mathematical model of the variable state of the incidence of epidemic diseases, which is of great importance for determining the quantity of vaccines and antiviral drugs to be produced. The information model according to the system of differential equations of the spread of the pandemic is illustrated in a structural diagram. The model is presented in a vector-matrix form and the state of equilibrium of the model in the spatial state is proved.The model of the spread of the pandemic was developed, whose implementation with a Matlab software package resulted in obtaining the curves of variation of the state. The developed computer model of the incidence of epidemic diseases can be used to make a projection of the number of infected people, as well as intensity of the process of disseminating information and ideas in the community.
The Correlation between English Reading Habit and English Reading Comprehension for EFL Students
Authors: Andriani Stevi Indarti , Ariyanti  
Published: October 2021

This research focused in Reading Habit and Reading Comprehension in students' English ability in second grade. The result of data obtained from SMP Negeri 26 Samarinda second grade. There were four classes in second grade, while the number of each class is 32 students. Thus, there were 128 populations in second grade. For this research, the researcher used correlation technique quantitative analysis and simple random sampling to choose the sample until consists of 35 subjects as samples. The instruments used are the questionnaire and reading test. The researcher used a questionnaire and reading test with reading text and questions that the researcher has a choice after the researcher knowing how far skill reading text in second grade and how much valid the result from per question in try out test at Class 8A as the first research. And then, the researcher used a population of Class 8B, 8C, and 8D as secondary research for the tested questionnaire and reading test. There were 35 students chosen as the subject. The result from the correlation test is counted low negative correlation result (-0,358) with sig. p-value <0,05 (0,035). Based on the result of the tests, Ha Hypothesis is accepted and Ho Hypothesis is rejected.

Keywords: reading habit; reading comprehension
Treatment and prophylaxis of moderate and severe bronchopulmonary dysplasia in premature neonates
Authors: Bolonska A.V. , Sorokina O.Yu. 
Published: October 2021

Bronchopulmonary dysplasia in premature neonates leads to physical and mental developmental disorders and behavioral problems and associated with frequent rehospitalizations and long hospital stay. Study objective: to study the predictors of bronchopulmonary dysplasia development in premature neonates in structure of intensive care. Study design: A retrospective cohort analysis was performed in 127 children recruited from two NICU of Dnipro between January 2016 to March 2020. Inclusion criteria: preterm neonates 28-32 gestation weeks with respiratory distress syndrome (RDS). Results demonstrated that every day of mechanical ventilation, supplemental oxygen with FiO2 more than 30% and cardiac drugs usage increased risk of bronchopulmonary dysplasia development by 15-20%. In conclusion, finding out predictors of bronchopulmonary dysplasia helps to improve and prudently use usual treatment regimens in premature neonates and decrease the frequency of moderate and severe bronchopulmonary dysplasia.
Formation of initial changes in hemodynamics and fluid compartments in high surgical risk patients under the influence of acute abdominal pathology
Authors: Kravets O.V. , Yekhalov V.V. , Krishtafor D.A. , Zozulia O.O. , Volkov O.O. , Vlasov O.O. 
Published: October 2021

Among the main factors of pathological changes that accompany acute abdominal pathology are the inflammatory process of the peritoneum and fluid deficiency due to its pathological losses. The aim of our study was to analyze the initial state of fluid compartments of the body and hemodynamics in high surgical risk patients with acute surgical abdominal pathology. There were examined 157 patients with acute abdominal pathology who underwent emergency laparotomy. The presence and severity of fluid deficiency were determined clinically by tissue hydrophilicity test by P.I. Shelestiuk, biochemically – by assessing the levels of hematocrit, hemoglobin, erythrocytes, blood electrolytes, vasopressin (ADH) and brain natriuretic propeptide (proBNP), as well as the mean erythrocyte volume and plasma osmolarity. Variables of fluid compartments of the body and central hemodynamics were studied using the non-invasive bioimpedancemetry. Based on the values of oxygen concentration in arterial and venous blood, total oxygen consumption (VO2) and delivery of oxygen (DO2), oxygen extraction ratio (O2ER) were calculated. The detected changes indicate intravascular fluid deficiency and concomitant hemoconcentration with normal electrolytes levels and plasma osmolarity. In patients with high surgical risk and moderate dehydration according to P.I. Shelestiuk, urgent surgical pathology of the abdominal cavity reduces extracellular fluid volume by 19.1% (p=0.019) of the reference by reducing the volume of the interstitium and intravascular fluid respectively by 20.7% (p=0.002) and 16.3% (p=0.001) of regional values, which forms in patients a state of "volume depletion" of moderate severity. This is accompanied by an increase in the ADH concentration by 16.7% (p=0.041) above reference and normal proBNP levels. Stroke volume decreases by 28.8% (p=0.021) against tachycardia (increase in heart rate by 39.7% (p=0.001) above normal) and vascular spasm (increase in systemic vascular resistance by 86.9% (p=0.001) above reference), which supports the normodynamic type of blood circulation (cardiac index – 3.2 (0.4) l/min/m2) with the decrease in stroke index and peripheral perfusion index by 41.3% (p=0.002) and 55.2% (p=0.002) from reference, respectively. DO2 decreases by 11.1% (p=0.011) from reference with VO2 increased by 16.3% (p=0.004) above reference, which leads to a decrease in oxygen utilization by 7.2% (p=0.041) from reference.
Domestic and school violence in short stature children with growth hormone deficiency
Authors: Aryayev M.L. , Senkivska L.I. 
Published: October 2021

The work is devoted to assessing the frequency of family (neglect, aggressive methods of punishment) and school (bullying) violence among short stature children with growth hormone deficiency (GHD) in comparison with children with normal growth.There were 94 children with GHD in the main group at the age of 7.2±0.4 years. The control group included 310 healthy children aged 7.1±0.3 years. Signs of domestic violence (neglect, aggressive methods of punishment) and violence at school (school bullying) were identified by questioning children and parents. School bullying was assessed using The Olweus Bully/Victim Questionnaire, adapted in Ukrainian and Russian. To check the statistical hypothesis on differences of relative frequencies, in two independent samples, the criteria of хі-square (χ2) was used. No differences were found in the frequency of neglect in the main group (8.5%) compared to the control group (9.5%), p>0.05. An equally low frequency of the use of non-aggressive methods of upbringing without physical and psychological punishment was found both in the main and in the control groups: 31.9% compared to 39.6% (p=0.25).There was no increased physical aggressiveness towards children with GHD: the frequency of physical punishment was 29.8% and did not differ from the control group by 35.3% (p=0.4). Psychological methods of punishment were used more often (38.3%) in the main group in comparison with the control group (25.1%); p=0.04.There was an increased frequency of school bullying in relation to children with GHD (27.2%: 18.1-36.3) compared with the control group (17.7%: 13.4-22.0), p=0.04. The frequency of school bullying in boys of the main group was 2 times higher than in boys of the control group. School bullying victims in the main group, compared with the control group, were more likely to feel depressed (30.8% versus 12.7%; p=0.05), less often had good friends (42.3% versus to 78.2%; p=0.001) and felt loneliness more often (26.9% in relation to 9.1%; p=0.04).
Applying of informational model of nutrition ration calculation for compensation of energy losses of the Ukrainian Armed Forces servicemen
Authors: Deputat Yu.M. , Gulich M.P. , Savytskyi V.L. , Ivanko O.M. , Levit Yo.R. , Bogomolets O.V. 
Published: October 2021

The article is devoted to the research of the problem of compensation of energy losses of servicemen doing qualification course of the UAF Special Operations Forces as well as development of the method of promp response of the officials of food service on changing of energy losses of servicemen on different phases of qualification course by corresponding correction of their daily nutrition ration. The aim of work was directed for development and substantiation of informational model of nutrition ration calculation for compensation of energy losses of the Ukrainian Armed Forces servicemen. Time and tabular method of energy losses calculations, calculations of ration composition, instrumental estimations, laboratory and statistics assessments were used as methods of research. Calculations of informational model were done in Microsoft Excel 2007 functional environment. The description of informational polyparametrical model of the computational system of nutrients composition and energy value of servicemen daily nutrition ration depending on revealed energy losses doing qualification course of UAF Special Operations Forces has been presented. The model is meant for operative calculations of nutrients composition and energy value for compensation of energy losses of corresponding servicemen doing different phases of qualification course. Informational model got approval and was implemented in the UAF Special Operations Forces activities.
A Comparative Study of Groundwater between Geological Groups of Southern Benue Trough, Nigeria Using Modelling Approach
Authors: Eyankware Moses Oghenenyoreme , Obasi Philip Njoku , Ogwah Christoper 
Published: October 2021

Groundwater studies were carried out between two geological groups to evaluate factors that influences groundwater geochemistry. To achieve this, 30 groundwater samples were collected. Parameters such as pH, Electrical Conductivity (Ec), Total Dissolved Solids (TDS), Total Hardness (TH), and hydrochemical characteristics (Na2+, K+ , Ca2+, Mg2+, HCO3¯, NO3¯, Cl¯, CO23¯, and SO42¯) of groundwater were determined. Findings revealed that the pH value for Asu River Group ranges from 5.3 to 7.5, and that of Eze Aku Group ranges from 4.1 to 7.9. It was observed that areas around the mines had low pH values. Analyzed results that were obtained were interpreted using various hydrogeochemical models. Parson plots reflected that groundwater within the two geological groups fell within Ca˗Mg˗SO4 and Ca˗Mg˗Cl. Results from End˗member plots showed that 96% of groundwater samples analyzed were categorized under carbonate weathering, 4% fell silicate weathering. Gibbs plots revealed that interactions between groundwater and surrounding host rocks are mostly the main processes responsible for chemical characteristics of groundwater, Diamond field plots suggested that groundwater within the study were categorized to be high in Ca + Mg & SO4 + Cl, the plot of Ca2+/(HCO3¯+SO42¯) against Na+/Cl¯ revealed that groundwater was considered to be within the natural state for the two group. The plot of TDS against TH showed that groundwater is classified as soft freshwater. The study revealed there was no significant difference between factors that influence groundwater within the two geological.
فاعلية استراتيجية التدريس التبادلي في تحصيل مادة طرائق تدريس اللغة العربية وتنمية مهارات التفكير ما وراء المعرفة لدى طلبة قسم اللغة العربية في جامعة بابل
Authors: كامل جبار سهاد 
Published: October 2021

يهدف البحث إلى قياس فاعلية استراتيجية التدريس التبادلي في تحصيل مادة طرائق تدريس اللغة العربية وتنمية مهارات التفكير ما وراء المعرفة لدى طلبة قسم اللغة العربية في جامعة بابل.
ولتحقيق البحث وضعت الفرضيتين الصفريتين التي تفترض عدم وجود فرق ذي دلالة معنوية عند مستوى (0,05) بين متوسط درجات الطلبة في المجموعتين (التجريبية والضابطة) في الاختبار البعدي لمادة طرائق تدريس اللغة العربية ومهارات التفكير ما وراء المعرفة.
واتبعت الباحثة المنهج شبه التجريبي ذا الاختبار البعدي، وكانت عينة البحث قد تكونت من(56) طالباً وطالبة و تقسموا إلى مجموعتين تجريبية وعددها(28) طالباً وطالبة, درست باستخدام استراتيجية التدريس التبادلي والضابطة وعددها (28) طالباً وطالبة , درست بالطريقة الاعتيادية وتمت مكافئة المجموعتين في المتغيرات الدخيلة.
وأعدت الباحثة أداتا, الأولى اختبار تحصيلي تكون من (40) فقرة ، والأداة الثانية هي مقياس التفكير ما وراء المعرفة والذي تكون من (42) فقرة , وتم أجراء لكلاهما الصدق والثبات والتحليل الإحصائي لفقراتهما .
وكان من نتائج البحث تفوق المجموعة التجريبية التي هي باستخدام استراتيجية التدريس التبادلي على المجموعة الضابطة في التحصيل والتفكير ما وراء المعرفة .