bluuebunny/crossref_metadata_2025_split huggingface dataset:
Malaya Transformed
Authors: Keo Bernard Z 
Published: January 2025

Abstract
In response to the rapid loss of Malaya and Singapore to the Japanese during World War II, British colonial planners in London devised comprehensive reforms for Malaya underpinned by the creation of a new unified administrative structure, the Malayan Union. The sudden end of the war in 1945 caught the British unawares and resulted in a violent interregnum between the surrender of Japanese forces and the restoration of British rule in Malaya. The violence of the interregnum served as a catalyst for Peranakan opposition to Penang and Malacca’s connection to the Malay States as part of the Malayan Union in 1946. The subsequent intensification of ethnic Malay nationalism in response to the Union, coupled with Singapore’s exclusion from the new administrative entity, exacerbated Peranakan anxieties about their place in the new Malaya. Investigating the development of these concerns and anxieties, this chapter locates the origins of Peranakan political activism in the post-World War II period and highlights how this developed in opposition to the intensification of ethnonationalist sentiments during the short-lived Malayan Union experiment.
Epilogue
Authors: Keo Bernard Z 
Published: January 2025

Abstract
Since Malaya’s independence in 1957, the Peranakan seemingly experienced a radical transformation in identity. What was once a politically active community has, over the last sixty years or so, become a predominantly cultural one that has been appropriated by the state as a cultural heritage product to sell the idea of Malaysia’s success as a multicultural country on the global tourism marketplace. This brief Epilogue discusses the depoliticization and commodification of the Peranakan by the Malaysian (and Singaporean) states, examining how the Peranakan have been remembered and forgotten in the public imagination, focussing particularly on how they have been portrayed in museums and in popular literature.
Accounting for local incidence when estimating rotavirus vaccine efficacy among countries: a pooled analysis of monovalent rotavirus vaccine trials
Authors: Amin Avnika B , Waller Lance A , Tate Jacqueline E , Lash Timothy L , Lopman Benjamin A 
Published: January 2025

Abstract
Rotavirus vaccine appears to perform sub-optimally in countries with higher rotavirus burden. We hypothesized that differences in the magnitude of rotavirus exposures may bias vaccine efficacy (VE) estimates, so true differences in country-specific rotavirus VE would be exaggerated without accommodating differences in exposure. We estimated VE against any-severity and severe rotavirus gastroenteritis (RVGE) using Poisson regression models fit to pooled individual-level data from Phase II and III monovalent rotavirus vaccine trials conducted between 2000 and 2012. The standard approach model included terms for vaccination, country, and a vaccination-country interaction. Other models used proxies for exposure magnitude like severe RVGE rate or age at severe RVGE instead of country. Country-specific proxies were calculated from placebo group data or extracted from an external meta-analysis. Analyses included 83,592 infants from 23 countries in the Americas, Europe, Africa, and Asia. Using the standard approach, VE against severe RVGE substantially varied (10-100%). Using the severe RVGE rate proxy brought VE from all but two countries between 80% and 86%. Heterogeneity for VE against any-severity RVGE was similarly attenuated. Adjusting for exposure proxies reduced heterogeneity in country-specific rotavirus VE estimates. This phenomenon may extend to other vaccines against partially immunizing pathogens with global disparities in burden.
A novel approach for inferring effects on pregnancy loss
Authors: Leung Michael , Rowland Sebastian T , Modest Anna M , Hacker Michele R , Papatheodorou Stefania , Wei Yaguang , Schwartz Joel , Coull Brent A , Wilson Ander , Kioumourtzoglou Marianthi-Anna , Weisskopf Marc G 
Published: January 2025

Abstract
Identifying the determinants of pregnancy loss is a critical public health concern. However, pregnancy loss is often not noticed, and even when it is, it is inconsistently recorded. Thus, past studies have been limited to medically-identified losses or small, highly selected cohorts, which can lead to biased or non-generalizable results. We show mathematically and through simulations a novel approach that overcomes this measurement challenge to infer effects about pregnancy loss by utilizing more available data: the number of conceptions that led to live births—i.e., live-birth-identified conceptions (LBICs). We simulated ten years of conceptions, pregnancies, losses, and births under several confounding patterns, and two NO2-pregnancy loss relationships (no effect, mid-gestation effect). We fitted distributed lag models (DLMs) adjusted for season, year, and temperature, and assessed model performance through bias and coverage. Our simulations showed that our models, across all scenarios, identified the two NO2-pregnancy loss relationships with appropriate coverage (&gt;90% of confidence intervals captured the true effect) and low bias (never exceeded ±2%). In an applied example using NO2—a traffic emissions tracer—and live birth data from a large tertiary-care hospital in Massachusetts, USA, we found that higher prenatal NO2 was associated with more pregnancy losses. Our proposed approach based on LBICs provides an alternative way to study causes of pregnancy loss.
Energy Metric Prediction for Double Insertion Mutants via the RoseNet Deep Learning Framework
Authors: Coffland Sarah , Christensen Katie , Hutchinson Brian , Jagodzinski Filip 
Published: January 2025

Abstract
Studying the structural and functional implications of protein mutations is an important task in computational biology and bioinformatics. We leverage our previously proposed RoseNet neural network architecture to predict energy metrics of proteins with double amino acid insertions or deletions (InDels). We train models on previously generated benchmark datasets containing the exhaustive double InDel mutations for three proteins, as well as an additional three proteins for which ∼145k random mutants, each with two InDels, have been generated. We expand on our previous work by evaluating three additional proteins and analyzing domain features that impact the prediction capabilities of RoseNet. These features include InDels into secondary structures and the solvent accessible surface area (SASA) scores of the residues. We uncover further evidence to support that RoseNet has a higher proficiency of generalizing to unseen residue combinations than unseen insertion positions. We also observe that RoseNet produces higher quality predictions when inserting into a β-sheet over an α-helix. Additionally, when the insertions fall in an area of high SASA, RoseNet often displays better performance than inserting into areas of low SASA.
Deciduous and evergreen perennials have higher antioxidant levels and more reactive oxygen species-susceptible chlorophyll-binding proteins
Authors: Nisbett Kenyon J , Rostami Nicki , Failas Dhan A , Brown Jason C L 
Published: January 2025

Abstract
Perennials live longer than annuals, yet the underlying physiological mechanisms responsible are poorly understood. We gathered data from published reports to investigate two hypotheses based on the oxidative stress theory of ageing. The first hypothesis was that perennials maintain higher antioxidant levels to neutralize reactive oxygen species (ROS) better, before they cause oxidative damage. Although carotenoid levels did not differ between annuals and perennials, we found that deciduous perennials had higher activity of the ascorbate–glutathione cycle, and evergreen perennials had higher activity of superoxide dismutase (SOD, EC 1.15.1.1). The second hypothesis was that chlorophyll-binding proteins of perennials have a lower proportion of ROS-susceptible amino acids to protect chlorophyll better from oxidative damage. Contrary to our predictions, although LHCI, LHCII, CP26, and CP29 showed no difference in amino acid composition between annuals and perennials, D1 protein and CP24 had a higher proportion of ROS-susceptible amino acids in both deciduous and evergreen perennials. By being more susceptible to ROS attack, these proteins might minimize oxidative damage to chlorophyll and/or contain oxidative damage within the photosystems such that it does not spread to other cell regions.
Relationships among flight traits, genetic differentiation and habitats in two closely related species of the genus Synuchus (Coleoptera: Carabidae)
Authors: Shimizu Takashi , Kubota Kôhei , Ikeda Hiroshi 
Published: January 2025

Abstract
The degeneration of flight ability has contributed to the diversification of beetles, which are among the most diverse groups in the world. Over the course of flight ability degeneration, intraspecific polymorphisms in flight traits occur. The type of habitat in which degeneration of flight ability is likely to occur is an important issue for understanding the diversification process of beetles, but this topic has rarely been studied in detail. In this study, we examined two closely related species (one species with intraspecific polymorphisms in the hind wings and the other an apterous-monomorphic species) of the genus Synuchus to clarify this issue. Our study indicated that these two species were morphologically and genetically related, but they showed contrasting genetic differentiation patterns and inhabited different environmental conditions. In particular, the apterous-monomorphic species seemed to be isolated in mountainous environments with four major climatic and terrain characteristics (cool, heavy precipitation in winter, large temperature and precipitation differences, and low continuity among habitats), and this isolation might have contributed to their complete loss of flight ability and geographical genetic differentiation via further suppression of gene flows between populations.
Survival, not reproduction, drives population growth of a neotropical mammal (Philander quica) in a seasonal environment
Authors: Ferreira Mariana S , Zangrandi Priscilla L , Menezes Antonio A , Vieira Marcus V 
Published: January 2025

Abstract
Seasonality is a prevalent environmental feature in tropical forests and can shape the life history of organisms subjected to regular and periodic changes in temperature and rainfall. Tropical forest marsupials usually reproduce seasonally in response to limited productive periods. This seasonality in reproduction may have an impact on other vital rates and contribute differently to population growth rate (λ) in different seasons. Here, we employed a periodic matrix population model and elasticity analysis to assess the potential contribution of survival, maturation, and reproductive rates to λ in both dry and wet seasons for the marsupial Philander quica. Survival played a predominant role over reproduction in shaping population dynamics, with subadult and pouch young survival exhibiting critical roles in dry and wet seasons, respectively. Despite unpredictable environmental perturbations such as the La Niña phenomenon, the predominance of survival in driving population growth underscores the resilience of marsupial life histories and inherent constraints shaping evolutionary trajectories.
Psychosocial information sharing to improve equity in kidney transplant evaluation
Authors: Wilk Adam S. , Huml Anne M. , Urbanski Megan , Muench Dorothy , Fischer Kristen M. 
Published: January 2025

Purpose of review
Increasing transplant access overall and particularly among historically underserved and marginalized patient groups is a shared goal nationwide. Patient challenges with psychosocial factors, such as social support and health literacy, are recognized as among the top reasons patients may not be referred, evaluated, or waitlisted, key steps along the pathway to transplantation. Yet referring providers’ (e.g., dialysis clinics’) and transplant centers’ processes for measuring, communicating about, and addressing patients’ psychosocial challenges are inconsistent, can emphasize measures more relevant to dialysis care than transplant care, and are highly susceptible to implicit bias.

Recent findings
In this article, we illuminate the opportunity to standardize the patient psychosocial information that dialysis clinics and other nephrology care providers share with the transplant center when referring a patient for transplant evaluation. We highlight potential benefits and trade-offs to this approach and describe how regional coalitions comprising patients, caregivers, and community members can support developing and implementing a standardized template for this purpose, as well as the objectives that the coalition's efforts should pursue to this end.

Summary
Standardized templates for psychosocial information sharing at referral represent a key opportunity to improve quality, efficiency, and equity in pretransplant care as well as transplant access outcomes broadly.
Factors Associated with Retention in HIV Care within 12 months Postpartum: A Retrospective Cohort Study
Authors: Dang Tran , Anderson Jean , Powell Anna M 
Published: January 2025

Background:
Loss to follow-up to HIV care following delivery puts birthing parents with HIV at higher risk of loss of viral suppression, disease progression, and HIV partner transmission. This study assessed factors associated with retention in postpartum HIV care.

Methods:
This is a retrospective cohort study at a single academic medical center and included patients followed from January 2014 to December 2022. The primary outcome was retention in postpartum HIV care (any healthcare encounter discussing HIV medication adherence or viral load within 12 months postpartum). Data was analyzed using Chi-square and student T-test for discrete and continuous variables. Univariate and multivariable log regressions were used to measure independent associations on care retention and healthcare utilization outcomes.

Results:
Of the 111 patients with planned follow up at our facility, 93 (83.8%) of participants had ≥ 1 HIV care encounter within 12 months of delivery. Participants had a mean age of 31.2 (± 5.84), were predominantly Black (79.3%), non-Hispanic (91%), non-U.S. born (57.5%) with substantial exposure of prior IPV (29.6%). Participants retained in care were more likely to use ART during pregnancy (92/99% vs 16/94.2%, P=0.01) and have viral suppression at delivery (n= 83/90% vs 12/67%, P=.02). Retention in care was negatively associated with substance use during pregnancy (aOR 0.29, 95% CI 0.09-0.95) following adjustment for social health covariates.

Conclusion:
While almost 84% of participants were retained in HIV care within 12 months of delivery, substance use in pregnancy was a significant risk factor for HIV care attrition postpartum.
Neuropsychiatric Outcomes in Children and Adolescents with Perinatally Acquired HIV: A Systematic Review and Meta Analysis.
Authors: Horton Rebecca H , Mcintosh Amy , Ostinelli Edoardo G , Harriss Elinor , Fazel Mina 
Published: January 2025

Objective:
The objective of this study is to define the neuropsychiatric challenges including developmental delay, cognitive impairment and psychiatric illness faced by children with perinatally acquired HIV.

Data Sources:
Nine databases were searched on 30/05/2023: MEDLINE, Embase, and PsycINFO (all via Ovid SP); CINAHL and Child Development and Adolescent Studies (via EBSCO); the Web of Science Core Collection; Scopus; ProQuest Dissertations and Theses Global; and WHO Global Index Medicus. No limits were applied. Search strategies incorporated keywords and thesaurus headings to describe children and adolescents aged 0-25 with perinatally acquired HIV and terms to describe the spectrum of neuropsychiatric impairment.

Study selection:
Entries were reviewed by two independent reviewers. Studies were included if they involved a population of children with perinatally acquired HIV and investigated a neurological or psychiatric outcome.

Main outcome measures:
Hypothesis that children with pHIV would have more neuropsychiatric challenges than children without pHIV was formulated before the study. Main outcome measures include incidence and severity of cognitive impairment, developmental delay and psychiatric illness in children with pHIV.

Results:
45 studies on cognitive impairment were included of which eight studies were included for meta-analysis and demonstrated a standardised mean difference of -0.508 where children without HIV had higher cognitive scores (95% CI -0.7903; -0.2272). 15 studies on developmental delay were included of which nine were included for meta-analysis and demonstrated, for motor delay, a standardised mean difference (SMD) of -0.794 where children without HIV achieved higher motor function scores (95% CI: -0.9986 to -0.590; ) and for cognitive delay a SMD of -0.697 where children without HIV achieved higher cognitive function scores (CI -0.976 to -0.417;). 39 studies on psychiatric illness were included with an odds ratio for anxiety and depression of 1.105, suggesting that children with HIV had slightly higher odds of developing anxiety or depression, however this result was not significant (CI: 0.778 – 1.571).

Conclusions:
Children with perinatally acquired HIV may have a greater cognitive impairment, motor and cognitive delay and would likely benefit from tailored approaches to improve their outcomes.
Tech facilitated fairness: examining the impact of technology on perceived fairness in interpersonal conflict resolution
Authors: Deshpande Amruta , Raut Rajesh , Kaul Natashaa , Mittal Amit 
Published: January 2025

Purpose
Conflict resolution is crucial to nurturing workplace harmony and creating a positive environment. This study aims to evaluate the relationship between perceived fairness, choice of technology and conflict resolution in the case of full-time employees from various sectors. The scope is limited to examining the influence of perceived fairness (PF) and the impact of technology on interpersonal conflict resolution (ICR), with age and designation being control variables.

Design/methodology/approach
A quantitative research design was used, and data was collected through a questionnaire distributed to 450 respondents, with 420 participants’ responses included in the analysis. Structural equation modeling using the SmartPLS software was then applied.

Findings
The findings revealed that perceived fairness has a significant positive impact on interpersonal conflict resolution, as did the use of technology. Age significantly influenced the relationship, while designation did not show an important relationship.

Practical implications
The results suggest that organizations should prioritize perceived fairness in their policies and practices to create a conflict-resolving environment. Furthermore, they can leverage technology to enhance conflict resolution processes as the workplaces accept hybrid as a way of work. These findings can also guide practitioners in fostering positive workplace climates by effectively managing conflicts.

Originality/value
This study contributes to the existing literature by examining the relationship between perceived fairness, technology and conflict resolution. It expands understanding of the factors influencing conflict resolution and highlights the importance of fairness and technology. The findings have practical implications for organizations seeking to enhance conflict management strategies.
Exploring the impact of technostress on the work–life boundary of UK academics during the coronavirus pandemic
Authors: Mordi Chima , Akanji Babatunde , Ajonbadi Hakeem 
Published: January 2025

PurposeGiven the debilitating ways the COVID-19 global crisis altered peoples’ work–life affairs, this paper explores the effect of technology-related stress that UK academics encountered working from home during the lockdown. Drawing on boundary management theory, the study uncovered how the extreme deluge of teleworking heightened technostress that made it challenging to either segment or integrate work–life boundaries as both domains became exceedingly blurry, which necessitated a novel experience conceptualised as boundary violations with negative outcomes ensuing.Design/methodology/approachThe dataset consists of semi-structured interviews with 32 academics in the UK. We rely on the interpretative paradigm using a qualitative research method.FindingsThe results reveal how the proliferation of technostress paved the way for a rising loss of boundary identity between professional and private affairs, morbidity and techno-isolation, which reinforced work–family conflict. The study’s findings highlight the processes involved in boundary disruption, as both domains were eroded in the wake of the unprecedented level of telework, which resulted in boundary violations (conceived as instances in which actions, conditions or situations either breach or neglect desired boundary management practices).Research limitations/implicationsThe challenges involved in teleworking have seldom been the focus of work-life studies using role boundary management constructs in relation to the coronavirus pandemic. Hence, our study provides novel contributions to the contextually limiting conditions that have thwarted the well-established segmentation and integration processes of boundary management by conceptualising the boundary violations orchestrated by the invasive tendencies of virtual working environments and rising technostress caused by the coronavirus pandemic.Originality/valueWhile research on teleworking has consistently established more positive outcomes for both employees and organisations, the novelty of the present study is its contributions to the negative implications of remote working during the coronavirus pandemic, one of which is technostress. The study further discusses work–life implications for future research on the factors that made remote working particularly challenging during the coronavirus crisis.
Optimization of the non-periodic inspection policy for a power supply system using genetic algorithm
Authors: Moakedi Hamid , Hajizadeh Ebrahimi Fazel 
Published: January 2025

PurposeThe purpose of this paper is to derive the optimal inspection policy for a power supply system which consists of two components: a capacitor bank and a transformer. The capacitor bank has two states: healthy and hidden failure. Its failure is detected only by inspection, and the delay in detection increases the cost of electricity consumption. The transformer has three states: healthy, defective and obvious failure. It continues to work after being defective, but if the defect is not detected and repaired in time, it becomes an obvious failure. The defect is detected only by inspection, but the obvious failure is self-announcing.Design/methodology/approachThe expected total cost of the system over a limited time horizon for a given inspection schedule is first modeled mathematically, and then an efficient genetic algorithm is designed to find the nearly optimal non-periodic inspection policy such that the expected total cost of the system is minimized.FindingsThe results show that, firstly, the higher the failure rate of the system components, the non-periodic inspection policy is more economical than the periodic one. Secondly, the proposed genetic algorithm reaches the nearly optimal solution in a shorter time with less computational effort compared to the A-star search algorithm.Originality/valueUsing the proposed approach, the nearly optimal non-periodic inspection schedule over a finite time horizon can be easily obtained for the power supply system. As a result of the implementation of this policy, the inspection and maintenance costs have been reduced, and it can have a significant impact on energy price.