bluuebunny/crossref_metadata_2025_split huggingface dataset:
Foot Strike Patterns During Overground Distance Running: A Systematic Review and Meta-Analysis
Authors: Bovalino Stephen P. , Kingsley Michael I. C. 
Published: November 2021

Abstract
Background
Investigations of foot strike patterns during overground distance running have foci on prevalence, performance and change in foot strike pattern with increased distance. To date, synthesised analyses of these findings are scarce.

Objective
The key objectives of this review were to quantify the prevalence of foot strike patterns, assess the impact of increased running distance on foot strike pattern change and investigate the potential impact of foot strike pattern on performance.

Methods
Relevant peer-reviewed literature was obtained by searching EBSCOhost CINAHL, Ovid Medline, EMBASE and SPORTDiscus (inception-2021) for studies investigating foot strike patterns in overground distance running settings (> 10 km). Random effects meta-analyses of prevalence data were performed where possible.

Results
The initial search identified 2210 unique articles. After removal of duplicates and excluded articles, 12 articles were included in the review. Meta-analysis of prevalence data revealed that 79% of long-distance overground runners rearfoot strike early, with prevalence rising to 86% with increased distance. In total, 11% of runners changed foot strike pattern with increased distance and of those, the vast majority (84%) do so in one direction, being non-rearfoot strike to rearfoot strike. Analysis of the relationship between foot strike pattern and performance revealed that 5 studies reported a performance benefit to non-rearfoot strike, 1 study reported a performance benefit to non-rearfoot strike in women but not men, 4 studies reported no benefit to non-rearfoot strike or rearfoot strike, and no studies reported a performance benefit of rearfoot strike over non-rearfoot strike.

Conclusion
Most overground distance runners rearfoot strike early, and the prevalence of this pattern increases with distance. Of those that do change foot strike pattern, the majority transition from non-rearfoot to rearfoot. The current literature provides inconclusive evidence of a competitive advantage being associated with long-distance runners who use a non-rearfoot strike pattern in favour of a rearfoot strike pattern.
Shapley value cooperative game theory-based locational marginal price computation for loss and emission reduction
Authors: Veeramsetty Venkataramana 
Published: November 2021

AbstractAn iterative method based on Shapley Value Cooperative Game Theory is proposed for the calculation of local marginal price (LMP) for each Distributed Generator (DG) bus on a network. The LMP value is determined for each DG on the basis of its contribution to reduce loss and emission reduction, which is assessed using the Shapley Value approach. The proposed approach enables the Distribution Company (DISCO) decision-maker to operate the network optimally in terms of loss and emission. The proposed method is implemented in the Taiwan Power Company distribution network 7 warnings consisting of 84 buses and 11 feeders in the MATLAB environment. The results show that the proposed approach allows DISCO to operate the network on the basis of its priority between the reduction of active power loss and emission in the network
Glass fiber-reinforced composites in dentistry
Authors: Safwat Engie M. , Khater Ahmad G. A. , Abd-Elsatar Ahmed G. , Khater Gamal A. 
Published: November 2021

Abstract
Background
Enormous improvements in dental materials’ manufacturing for the aim of producing durable dental materials without compromising the aesthetic properties were developed. One of the approaches that fulfill this aim is the use of reinforcing glass fibers as fillers into dental materials, typically resin polymers, in order to obtain glass fiber-reinforced composites. Glass fiber-reinforced composite offered many advantages to the dental materials though some limitations were recorded in many literature.

Methods
In this review, a study of the glass fibers’ types, factors affecting the properties and the properties of glass fibers reinforced materials was carried out; in addition, research papers that experimentally studied their applications in dentistry were presented.

Conclusion
The success of glass fibers reinforced composites in dentistry depends on glass fibers’ composition, orientation, distribution, amount, length and adhesion; these factors once employed according to the required clinical situation would provide the essential reinforcement to the dental restorations and appliances.
Appropriate determination of the surgical transepicondylar axis can be achieved following distal femur resection in navigation-assisted total knee arthroplasty
Authors: Song Sang Jun , Lee Hyun Woo , Kim Kang Il , Park Cheol Hee 
Published: November 2021

Abstract
Background
Many surgeons have determined the surgical transepicondylar axis (sTEA) after distal femur resection in total knee arthroplasty (TKA). However, in most navigation systems, the registration of the sTEA precedes the distal femur resection. This sequential difference can influence the accuracy of intraoperative determination for sTEA when considering the proximal location of the anatomical references for sTEA and the arthritic environment. We compared the accuracy and precision in determinations of the sTEA between before and after distal femur resection during navigation-assisted TKA.

Methods
Ninety TKAs with Attune posterior-stabilized prostheses were performed under imageless navigation. The sTEA was registered before distal femur resection, then reassessed and adjusted after distal resection. The femoral component was implanted finally according to the sTEA determined after distal femur resection. Computed tomography (CT) was performed postoperatively to analyze the true sTEA (the line connecting the tip of the lateral femoral epicondyle to the lowest point of the medial femoral epicondylar sulcus on axial CT images) and femoral component rotation (FCR) axis. The FCR angle after distal femur resection (FCRA-aR) was defined as the angle between the FCR axis and true sTEA on CT images. The FCR angle before distal resection (FCRA-bR) could be presumed to be the value of FCRA-aR minus the difference between the intraoperatively determined sTEAs before and after distal resection as indicated by the navigation system. It was considered that the FCRA-bR or FCRA-aR represented the differences between the sTEA determined before or after distal femur resection and the true sTEA, respectively.

Results
The FCRA-bR was −1.3 ± 2.4° and FCRA-aR was 0.3 ± 1.7° (p < 0.001). The range of FCRA-bR was from −6.6° to 4.1° and that of FCRA-aR was from −2.7° to 3.3°. The proportion of appropriate FCRA (≤ ±3°) was significantly higher after distal femur resection than that before resection (91.1% versus 70%; p < 0.001).

Conclusions
The FCR was more appropriate when the sTEA was determined after distal femur resection than before resection in navigation-assisted TKA. The reassessment and adjusted registration of sTEA after distal femur resection could improve the rotational alignment of the femoral component in navigation-assisted TKA.

Level of evidence
IV.
Psychosocial support services provided for Syrian refugees with disabilities: a systematic review and thematic analysis
Authors: Alodat Ali M. , Alshagran Hanan I. , Al-Bakkar Al-Muatasem M. 
Published: November 2021

AbstractThis study systematically reviewed and thematically analyzed studies that investigated psychosocial support services provided to Syrian refugees with disabilities between 2011 and 2020. Nine studies published in the English language were identified from database searches (Google Scholar, PsychInfo, EBSCOhost, Web of Science, and Scopus). Results showed that the forms of psychosocial support services provided to Syrian refugees with disabilities were varied based on the nature of the study and the disability type. The results also provided detailed information about methods, participants, and findings of the identified studies. The thematic analysis results identified six themes that represent the factors related to the psychosocial support services, which were assessment, mental health, psychological well-being, rehabilitation, social participation, and vulnerability. This study provided a set of recommendations that may improve the quality of mental health and psychosocial support services provided to Syrian refugees with disabilities and their families, which are professional development, researches, and policy reforming.
Studies on the radiation dose, image quality and low contrast detectability from MSCT abdomen by using low tube voltage
Authors: Mokhtar A. , Aabdelbary Z. A. , Sarhan A. , Gad H. M. , Ahmed M. T. 
Published: November 2021

Abstract
Background
To study radiation dose, image quality and low-contrast cylinder detectability from multislice CT (MSCT) abdomen by using low tube voltage using the American College of Radiology (ACR) phantom. The ACR phantom (low-contrast module) was scanned with 64 MSCT scanner (Brilliance, Philips Medical System, Eindhoven, Netherlands) with 80 and 120 KVP, utilizing different tube current time product (mAs) range from 50 to 380 mAs. The image noise (SD), signal to noise ratio, contrast-to-noise ratio (CNR), and scores of low contrast detectability were assessed for every image respectively.

Results
From images analyses, the noise essentially increased with the use of low tube voltage. The CNR was 0.94 ± 0.27 at 120 KVP, and CNR was 0.43 ± 0.22 at 80 KVP. However, with the same dose, there were no differences of statistical significance in scores of low-contrast detectability between 120 KVP at 300mAs and 80 KVP at (200–380) mAs (p > 0.05). At 300 mAs, the CTDIvol obtained at 80 KVP was about 29% of that at 120 KVP. The CTDIvol obtained at 80 KVP were decreased from 5% at 50 mAs, to 37% at 380 mAs.

Conclusions
There is a possibility to decrease exposure of radiation virtually by reducing KVP from 120 to 80 KVP in examination of abdominal CT when the high tube current is used, though increasing image noise at low tube voltage.
Urethral mobilization and advancement technique in distal types of hypospadias: short-term local experience
Authors: Edan Obay Abdul Aziz 
Published: November 2021

Abstract
Background
A prospective study was conducted on 65 cases with distal hypospadias operated using the urethral mobilization technique between July 2017 and December 2019. Patients with proximal hypospadias and those with distal hypospadias, but with a hypoplastic urethra, were excluded from the study. In this technique, the urethral tube was mobilized proximally in a ratio of 3–4:1 (the ratio of mobilized urethral length to the initial distance between the native meatus and the tip of the glans) then positioned distally after creating wide glans wings. The aim of this study was to assess the outcome of the urethral mobilization technique in distal hypospadias in our center.

Results
The age of patients was ranged 9 months to 7 years old (mean 37.5 months); 17 (26%) cases were already circumcised. During the postoperative follow-up, 62 (95.4%) patients had a good caliber neomeatus with a good and straight urinary stream; the remaining 3 (4.6%) cases developed meatal stenosis which responded well to urethral dilatation. One (1.5%) patient had a minor retraction of neomeatus but remained within the glans and not requiring further intervention. Four (6%) cases developed minor hematoma which was resolved on conservative measures. Six (9.2%) patients developed minor wound infection which was treated with daily dressing and antibiotic coverage.

Conclusion
The urethral mobilization technique is a good choice for repairing distal hypospadias especially for boys who are previously circumcised as the preputial flap is not required in this technique. It provides good cosmetic and functional results, with a fewer complication rate.
Seismic low-frequency shadows and their application to detect CO2 anomalies on time-lapse seismic data: A case study from the Sleipner Field, North Sea
Authors: Anthony Emmanuel , Vedanti Nimisha 
Published: November 2021

The detection and underlying mechanism of prospect-scale seismic low-frequency shadows (LFSs) has been an issue of debate. Even though the concept of LFS is widely accepted, the practical applicability of the method remains limited due to few real field case studies and little understanding of the underlying attenuation mechanism. To characterize the attenuation phenomenon responsible for the occurrence of LFS in CO2-saturated formations, we use the diffusivity and viscosity of the fluid-saturated medium to derive a complex velocity function that characterizes a high-frequency attenuation phenomenon responsible for the occurrence of LFS in a CO2-saturated formation. Synthetic seismic data sets representing pre- and post-CO2 injection scenarios are generated using 2D diffusive-viscous equations to model the LFS and understand its occurrence mechanism. Furthermore, to demonstrate the applicability of LFS in a real field, a spectral decomposition analysis of time-lapse 3D seismic data of the Sleipner Field, North Sea, is carried out using the continuous wavelet transform. The LFSs are clearly detected below the reservoir base at frequencies lower than 30 Hz in the post-CO2 injection surveys. It is shown that the seismic low-frequency shadows are not artifacts but occur due to attenuation of the high-frequency components of the propagating seismic waves in the CO2-saturated Utsira Formation. The attenuation of these frequencies is a result of the diffusivity and viscosity of the fluid-saturated medium. The LFSs are localized anomalies at the base of the formation; hence, with the present approach, these anomalies cannot be related to the migration of the CO2 plume in the Utsira Formation.
Alveolar progenitor differentiation and lactation depends on paracrine inhibition of Notch via ROBO1/CTNNB1/JAG1
Authors: Cazares Oscar , Chatterjee Sharmila , Lee Pinky , Strietzel Catherine , Bubolz J. W. , Harburg Gwyndolen , Howard Jon , Katzman Sol , Sanford Jeremy , Hinck Lindsay 
Published: November 2021

ABSTRACT
In the mammary gland, how alveolar progenitor cells are recruited to fuel tissue growth with each estrus cycle and pregnancy remains poorly understood. Here, we identify a regulatory pathway that controls alveolar progenitor differentiation and lactation by governing Notch activation in mouse. Loss of Robo1 in the mammary gland epithelium activates Notch signaling, which expands the alveolar progenitor cell population at the expense of alveolar differentiation, resulting in compromised lactation. ROBO1 is expressed in both luminal and basal cells, but loss of Robo1 in basal cells results in the luminal differentiation defect. In the basal compartment, ROBO1 inhibits the expression of Notch ligand Jag1 by regulating β-catenin (CTNNB1), which binds the Jag1 promoter. Together, our studies reveal how ROBO1/CTTNB1/JAG1 signaling in the basal compartment exerts paracrine control of Notch signaling in the luminal compartment to regulate alveolar differentiation during pregnancy.
Selective internal radiation therapy for hepatic metastases of uveal melanoma: a systematic review
Authors: Alexander Harry , Wen Daniel , Chu Michael , Han Catherine , Hadden Peter , Thomas Robert , Bartlett Adam 
Published: November 2021

Objective:
Uveal melanoma (UM) commonly metastasizes to the liver. Treatment usually consists of liver-directed therapies, such as selective internal radiation therapy (SIRT). This review aimed to assess the effectiveness and safety of SIRT for hepatic metastases from UM.

Methods:
The study protocol is available at OSF (https://osf.io/vhyct/). EMBASE and MEDLINE were searched until July 2020, using terms related to SIRT and hepatic metastases from UM. Studies reporting outcomes of SIRT in patients with UM and at least one hepatic metastasis were included. Data on overall survival (OS), hepatic progression free survival (hPFS) or tumor response were collected. The Newcastle-Ottawa Scale (NOS) was used to assess risk of bias.

Results:
11 studies were included, reporting outcomes for 268 patients with hepatic metastases from UM. Most studies (n = 9, 81.8%) were retrospective. Disease control was achieved in 170 patients (67.5%) and the median OS from time of SIRT was 12.3 months. Median hPFS was 5.4 months. Low-grade side-effects were common but serious complications were infrequent. There were two treatment-related deaths. The median NOS score was 6 (moderate risk of bias).

Conclusion:
SIRT appears to be a safe and effective treatment for patients with unresectable hepatic metastases from UM. The certainty of our results is unclear due to predominantly retrospective data with moderate risk of bias. Further prospective studies are required to explore the role of SIRT in UM.

Advances in knowledge:
SIRT appears to be a safe treatment for patients with unresectable hepatic metastases from UM. Further prospective work is required.
Predicting axillary response to neoadjuvant chemotherapy: the role of diffusion weighted imaging
Authors: Graña-López Lucia , Pérez-Ramos Tania , Maciñeira Fiz Andrés , Villares Ángeles , Vázquez-Caruncho Manuel 
Published: November 2021

Objective:
The aim of this study is to investigate whether the primary tumour response to neoadjuvant chemotherapy (NAC), based on the increase in the ADC-values (apparent diffusion coefficient) within the breast lesion, could help to predict axillary complete response.

Methods:
We retrospectively included 74 patients who were treated with NAC followed by surgery at Lucus Augusti Hospital between January 2015 and September 2020. Simple logistic regression was used to evaluate the factors associated with axillary pathological complete response, including the changes in breast tumour ADC-values due to the treatment.

Results:
Axillary complete response was correlated with negative oestrogen receptor status, Her2 positivity and response of primary tumour. It was achieved in 31% of the patients. In addition, the increase in the tumour ADC-values with NAC was higher for responders. Among the tumours that demonstrated an increase in ADC-value &gt;0.92 ×10−3 mm2/s, 42.8% (15/35) showed axillary complete response. Eight (20.5%) breast cancers with an increase in ADC below the cut-off value were found to have no metastatic nodes after treatment (p = 0.038).

Conclusion:
Our results suggest that the performance of models predicting axillary response to NAC can be improved by adding the tumour response determined also using diffusion-weighted imaging.

Advances in knowledge:
For the fist time, we investigate the relation between tumour response to NAC, assessed using diffusion-weighted imaging, and axillary pathologic complete response.
Effects of sociodemographic and socioeconomic factors on stroke development in Lebanese patients with atrial fibrillation: a cross-sectional study
Authors: Malaeb Diana , Hallit Souheil , Dia Nada , Cherri Sarah , Maatouk Imad , Nawas George , Salameh Pascale , Hosseini Hassan 
Published: November 2021

Background: Non-communicable diseases, the major cause of death and disability, are susceptible to modifiable and non-modifiable risk factors. Atrial fibrillation (AF) increases the risk of stroke by 4 to 5 times and can lead to cardiovascular mortality. This study was conducted to assess the effects of different sociodemographic and socioeconomic factors on stroke development in patients with AF. Methods: A cross-sectional study was conducted between January and June 2018 on patients recruited from Lebanese community pharmacies. The CHA2DS2-VASc scoring system is utilized as a stroke risk stratification tool in AF patients. Participants with a previous physician diagnosis of AF, documented on medical records, were included in this study. Data was collected through a survey that was distributed to all eligible patients. Results: A total of 524 patients were enrolled in the study with a mean age (± SD) of 58.75 ± 13.59 years with hypertension (78.4%) being the most predominant disease. The results showed that obesity (Beta=0.61, p-value =0.011), retirement and unemployment compared to employment (Beta=1.44 and 1.44, p-value=0.001 respectively), divorced/widow compared to married (Beta=1.38, p-value =0.001) were significantly associated with higher CHA2DS2-VASc scores whereas high versus low socio-economic status (Beta=-1.03, p=0.009) and high school education versus primary education level (Beta=-0.49, p-value=0.025) were significantly associated with lower CHA2DS2-VASc scores. Conclusions: The study highlights that the CHA2DS2-VASc score is affected by the presence of various sociodemographic and socioeconomic characteristics in patients with AF. Thus, screening for those factors may predict the progression of cardiovascular disease and may provide an optimal intervention.
EMI radiation of power transmission lines in Malaysia
Authors: Fikry Azhan , Lim Siow Chun , Ab Kadir Mohd Zainal Abidin 
Published: November 2021

Background: There has been rising concern amongst the public regarding their home's proximity to high tension power transmission lines. The primary cause of fear is the impact of the electromagnetic interference (EMI) radiation on the nearby occupants' health. Despite the presence of national permissible limits of EMI radiation, there is still lack of information with regards to the EMI radiation of the types of power lines configuration in Malaysia. Methods: The electric and magnetic fields of several selected power transmission lines were simulated using the EMFACDC software program from the recommendation ITU-T K.90. Five types of power transmission lines available in Malaysia are considered. Results: It was found that the simulated electric and magnetic field levels at all the power lines' right of way (ROW) boundary complies with the prescribed exposure limit. However, the electromagnetic fields (EMF) level increases significantly as the separation distance is reduced from 30m. For a more conservative approach, the ROW can be set at 30m across all transmission voltage level and corridor area condition. Conclusion: It can be concluded that Malaysia's power transmission lines are within the prescribed exposure limits. To further minimize the electric and magnetic field level, it is recommended that the residential building should be built at least 30 meters away from the power transmission lines, especially for the 275kV double circuit, 275/132kV quadruple circuit, and 500kV double circuit lines.