bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sacrococcygeal teratomas in newborns: peculiarities in diagnostics and treatment of small-sized tumors
Authors: Gopienko Mikhail A. , Karavaeva Svetlana A. , Silkov Viacheslav B. , Uskov Oleg I. , Miagkova Irina E. , Belogurova Margarita B. 
Published: March 2021

Introduction. When revealing a sacrococcygeal tumor in pediatric patient (especially newborn), a germ-cell tumor (GCT) (mostly teratoma) should be suspected. Just observation in cases of such tumors of small size, which might look as an option, cannot be recommended.
Aim of study: to reveal the peculiarities of diagnostics and treatment of small-sized sacrococcygeal GCT in newborns.
Materials and methods. We analyzed the data of charts of patients with sacrococcygeal GCT from 2 clinics of St. Petersburg (pediatric surgical hospital CCMCSCHMT and pediatric oncological department of St. Petersburg Oncocenter) for past 15 years (20052019). Among 55 newborn patients the size of tumor varied, comprising 14 giant (over 14 cm in diameter), 18 large (1014 сm in diameter), 21 medium-sized (39 cm), and 2 small-sized teratomas (under 3 cm in diameter).
Results. In both cases of small-sized GCT prenatal ultrasound was unable to reveal the tumor. Those patients appeared by surgeon occasionally (being either not transferred to hospital from the delivery house after birth or coming because of some other reason). Both patients underwent radical surgery with excision of coccyx (histological diagnosis being mature teratoma) and are still under observation of oncologist (with no signs of relapse during 6 months and 21 months). During the same period (20052019) there were 5 girls treated in St. Petersburg Oncocenter, with sacrococcygeal GCT first diagnosed at older age (10 months 2 years 9 months). They all had less favorite course and prognosis (histologic variants being yolk sac tumor or embryonic carcinoma; having remote metastases in 2 cases, with relapse in 1 case, and lethal outcomes in 2 cases).
Conclusion. Small-sized sacrococcygeal GCT in newborns can bear a significant risk of delayed diagnosis with possible further malignization and formation of metastases, so active revealing and active surgical treatment in such cases is needed.
Study design guidelines
Authors: Sereda Andrey P. , Andrianova Marina A. 
Published: March 2021

Complying with certain requirements or, more precisely, following the guidelines for the design of a scientific publication helps to make it not only more comprehensible for reviewers and readers, but actually enhances the quality of work. For example, even if some aspects in design logic were fulfilled but not described, other researchers doing meta-analysis may wrongly but for a good reason downgrade such publication and exclude it from the analysis. understanding of the guidelines for study design ensures not only the proper description of the results but the initial planning of work. The CARE guidelines were established for reporting of clinical cases, STROBE for reporting observational studies (cohort and case-control studies), CONSORT for reporting randomized studies (these guidelines are often used also for other comparative and case series studies), STARD for reporting diagnostic studies, and PRISMa for reporting of systematic reviews and meta-analyses. The present paper describes the key aspects of those guidelines and provides templates for graphic display of study design in form of flow charts. evidently, we should not forget that each study is unique and there is always a place for a reasonable compromise between requirements and the real logic of the research in place.
The article is the reprint published with the permission of the copyright holder. Original article: Sereda AP, Andrianova MA. Study Design Guidelines. Traumatology and Orthopedics of Russia. 2019;25(3):165-184. doi: 10.21823/2311-2905-2019-25-3-165-184
Perceived Benefits and Barriers to Prenatal and Postpartum Exercises Among Child Bearing Women in Kano, Nigeria
Authors: Rajah Amina Suleiman , Bayero Umar Bilkisu , Hussein Zainab Muhammad , Lawal Auwal Khadija , Tashi Tijjani Faiza , Tukuntawa Abdulaziz Sulaiman , Rabiu Abdullahi Fatima 
Published: March 2021

BACKGROUNDPregnancy is a stressful phenomenon experienced by women, during which the body experiences dramatic anatomical, physiological, and psychological changes.AIMThe study examined perceived benefits and barriers to prenatal and postpartum exercises among pregnant women in Kano.METHODSThe study was a descriptive survey in which 400 consenting pregnant women attending antenatal clinic were recruited for a period of 3 months (November 2019 to January 2020, using systematic random sampling technique. A structured interviewer-administered questionnaire was utilized to elicit responses and the data obtained was analyzed using descriptive statistics of mean, standard deviation, and frequency distribution.RESULTSFindings showed that the respondents have a mean age of 26.86 ± 5.4 years which ranges from 17–47 years. Prenatal exercises may be associated with the prevention of excessive weight gain and/or gestational diabetes and/or preeclampsia. The study further revealed that most of the respondents agreed that postpartum exercises prevents vaginal and uterine prolapse and urinary incontinence, helps in losing post pregnancy body weight and prevents diastasis recti abdominis. The major barriers identified included lack of access to facilities, lack of family support, and cultural factors.CONCLUSION AND RECOMMENDATIONThe study concludes that there is a positive perception of the benefits of prenatal and postpartum exercises and therefore, recommends that maternity care givers should provide accurate, adequate, and relevant information and advocate increased social and family support.
Waiting as Performative and Relational: A Narrative Inquiry Study Into the Experiences of Women Who Use Substances
Authors: Dewart Georgia , Estefan Andrew , Clandinin D. Jean , Caine Vera 
Published: March 2021

Background and PurposeThe act of waiting in health care is becoming increasingly prevalent worldwide. Waiting in health care is not a neutral activity; it is filled with expectations marked by cultural and social norms. In this article, we consider the performative nature of waiting by reflecting on the experiences of two participants in a narrative inquiry study.MethodsDrawing on a narrative inquiry study focused on the experiences of three women who disclosed illegal substance use during their pregnancy or early postnatal period, we inquired into two participants' experiences of waiting. The study which took place in a large urban center in Western Canada, where the researcher connected with participants who faced numerous challenges due to poverty, stigma, and discrimination.ResultsSharing the narratives of Georgia Dewart, and participants Renate, and Marilynn, we explore the performative act of waiting in their interactions with health care. We consider the political and social implications of the act in order to explore the subtleties and overlooked consequences of waiting. This work encourages the nursing profession to address overlooked aspects of care, such as the act of waiting.Implications for PracticeOur findings draw attention to the normative expectations within participants' experiences of waiting. This work offers methodological considerations for those engaging with Butler's concept of performativity when considering everyday acts. We also challenge care providers to reflect on their experiences working with clients, families, and communities to consider both the relational and performative nature of these interactions.
HEATHCLIFF’S SELF ACTUALIZATION IN WUTHERING HEIGHTS BY EMILY BRONTE
Authors: Fatmawati Ririn 
Published: March 2021

This research discusses about Heathcliff’s Self-Actualization in Wuthering Heights written by Emily Bronte which is set in the Yorkshire moors of Northern England. The inductive method is used to make the discussion of the topic brief. It means that the analysis starts from the specific concept goes to general conclusion. The data used in this thesis are collected by library research. This article also applies Maslow’s Hierarchical Theory of motivation. There are five hierarchies of needs which have to be fulfilled before someone goes through to accomplish self actualization, those are physiological needs, safety needs, belongingness and love needs and the last needs are self-esteem needs. This article focuses on how Heathcliff fulfil his psychological need, how he get his safety need, how he get the belongingness and love need, how he reach his self-actualization.
. The research is to find Heathcliff succeeded to complete his self actualization in Wuthering Heights. Heathcliff can achieve his self-actualization because he wants to become a total kind of person to reach his dream whatever way he has done. He is able to unify Wuthering Heights and Thrushcross Grange, and making Hareton as slave.
3E – A new paradigm for the development of civil aviation
Authors: ORKISZ Marek , KUŹNIAR Michał 
Published: March 2021

IntroductionNowadays, in civil aviation, issues related to improving efficiency, reducing the costs of air operations as well as the negative impact of air transport on the environment are of increasing importance. These ideas allow the formulation of the paradigm relating to the development of air transport – ‘more Efficiently, more Economically, more Eco-friendly – 3E’. The article presents in a cross-sectional and synthetic way research conducted by leading scientific centres around the world as well as prototype aviation constructions designed by companies from the aviation industry. Benefits and disadvantages of future propulsions, such as purely electric, hybrid and distributed propulsions, were presented. Conclusions were formulated regarding further possible directions of civil aviation development, taking into account the improvement of its efficiency as well as economic and ecological indicators.
Phase Behavior and Physical Properties of Dimethyl Ether/Water/Heavy-Oil Systems Under Reservoir Conditions
Authors: Huang Desheng , Li Ruixue , Yang Daoyong 
Published: March 2021

SummaryPhase behavior and physical properties including saturation pressures, swelling factors (SFs), phase volumes, dimethyl ether (DME) partition coefficients, and DME solubility for heavy-oil mixtures containing polar substances have been experimentally and theoretically determined. Experimentally, novel phase behavior experiments of DME/water/heavy-oil mixtures spanning a wide range of pressures and temperatures have been conducted. More specifically, a total of five pressure/volume/temperature (PVT) experiments consisting of two tests of DME/heavy-oil mixtures and three tests of DME/water/heavy-oil mixtures have been performed to measure saturation pressures, phase volumes, and SFs. Theoretically, the modified Peng-Robinson equation of state (EOS) (PR EOS) together with the Huron-Vidal mixing rule, as well as the Péneloux et al. (1982) volume-translation strategy, is adopted to perform phase-equilibrium calculations. The binary-interaction parameter (BIP) between the DME/heavy-oil pair, which is obtained by matching the measured saturation pressures of DME/heavy-oil mixtures, works well for DME/heavy-oil mixtures in the presence and absence of water. The new model developed in this work is capable of accurately reproducing the experimentally measured multiphase boundaries, phase volumes, and SFs for the aforementioned mixtures with the root-mean-squared relative error (RMSRE) of 3.92, 9.40, and 0.92%, respectively, while it can also be used to determine DME partition coefficients and DME solubility for DME/water/heavy-oil systems.
The architecture of the SARS-CoV-2 RNA genome inside virion
Authors: Cao Changchang , Cai Zhaokui , Xiao Xia , Rao Jian , Chen Juan , Hu Naijing , Yang Minnan , Xing Xiaorui , Wang Yongle , Li Manman , Zhou Bing , Wang Xiangxi , Wang Jianwei , Xue Yuanchao 
Published: March 2021

Abstract
SARS-CoV-2 carries the largest single-stranded RNA genome and is the causal pathogen of the ongoing COVID-19 pandemic. How the SARS-CoV-2 RNA genome is folded in the virion remains unknown. To fill the knowledge gap and facilitate structure-based drug development, we developed a virion RNA in situ conformation sequencing technology, named vRIC-seq, for probing viral RNA genome structure unbiasedly. Using vRIC-seq data, we reconstructed the tertiary structure of the SARS-CoV-2 genome and revealed a surprisingly "unentangled globule" conformation. We uncovered many long-range duplexes and higher-order junctions, both of which were under purifying selections and contributed to the sequential package of the SARS-CoV-2 genome. Unexpectedly, the D614G and the other two accompanying mutations might remodel duplexes into more stable forms. Lastly, the structure-guided design of potent small interfering RNAs could obliterate the SARS-CoV-2 in Vero cells. Overall, our work provides a framework for studying the genome structure, function, and dynamics of emerging deadly RNA viruses.
A Comparison of Vegetative Climate of Artemisia Sieberi Besser and Artemisia Aucheri Boiss in Iran
Authors: Khodagholi Morteza , saboohi Razieh , Esfahani Ehasan Zandi 
Published: March 2021

Abstract
The relationship between plant species and climatic factors has always been a fundamental issue in plant ecology, and the use of multivariate statistical methods can be effective in revealing the relationship between climatic factors and plant species distribution. Therefore, in this study, climatic factors affecting the distribution of Artemisia sieberi and Artemisia aucheri, widely distributed in Iran, were investigated. For this purpose, 117 climatic factors were used, and to reduce the number of factors and determine the most important effective ones, a factor analysis was used by principal component analysis. The results showed that six factors including heating temperature, spring and summer precipitation, wind, autumn-winter precipitation, and dusty and cloudiness days explained 37.32%, 22.54%, 7.18%, 6.6%, 4.22%, and 4.15% of data variation, respectively. Together these seven factors account for 82% of data variation. The autumn-winter precipitation and heating temperature had the greatest impact on the presence of Artemisia sieberi and Artemisia aucheri, respectively, so that the autumn-winter precipitation was negative in areas where Ar.sieberi is observed. The heating temperature factor is negative in areas where Ar.aucheri is present, while it is positive in areas lacking Ar.aucheri. The study of the effect of environmental factors on Artemisia species distribution is very important in planning and management of natural resources, and Artemisia is one of the most important plants in the country's rangelands; therefore, the results of this research can be used for practical planning, management and reclamation of these rangelands.
Malaria Data Analysis Using Routine Surveillance Data, Sunyani Municipality, Ghana, 2020
Authors: Mohammed Abdul Gafaru , Tamal Christopher Sunkwa , Odikro Magdalene Akos , Bandoh Delia Akosua , Noora Charles Lwanga , Quarshie Prince Romeo , Afari Edwin , Kenu Ernest 
Published: March 2021

Abstract
IntroductionMalaria is endemic in Ghana, accounting for about 40% of all OPD diagnosis. Data on malaria is routinely collected as part of the IDSR monthly reporting forms. Sunyani municipality recorded 56,540 malaria cases in 2016 with about 35% of the cases occurring in children under five years of age. We analyzed malaria surveillance data to identify the distribution of malaria cases by person, place and time and determine the timeliness and completeness of malaria report submission in the municipality.MethodsWe analyzed malaria surveillance data in Sunyani municipality reported between 2015 and 2019 from the District Health Management Information System II. We calculated morbidity and mortality rates of cases by person and estimated proportion of cases by sub-districts. We performed trend analysis and calculated disease threshold levels. We presented the findings using tables and figures.ResultsOf 639,361 malaria cases suspected, 93.5% (597,512/639,361) were tested, of which 49.4% (295,458/597,512) was positive. Females accounted for 55.7% (164,436/295,458) of the morbidity. Children < 5 years recorded the highest proportion, 29.9% (88,135/295,458) of cases in the municipality. The case fatality rate was 3.7% (18/484) and 1.4% (7/484) for persons under age five and over age five, respectively. Abesim (6,276.03 per 10,000) recorded the highest number of cases, and the least cases were in New Dormaa (1,890.97 per 10,000). The majority of malaria cases were in May and October of each year. Antwi-krom recorded the highest rates of completeness and timeliness of 41.9% and 40.0% respectively.ConclusionMore females were diagnosed with malaria and children < 5 years recorded the highest proportion of cases in the municipality. Abesim recorded the highest proportion of malaria cases during the period. High patterns of malaria transmissions occurred during months of high rainfalls. None of the sub-districts met the WHO target for timeliness and completeness of report submission. The NMCP should consider interventions such as SMC among children under five, in the Sunyani municipality.
Is there a role for Amniotic Membrane as an antifibrotic agent in MMC-Augmented Trabeculectomy?
Authors: Roque Joana , Vaz Fernando Trancoso , Basto Rita , Henriques Susana , Lopes Ana Sofia , Silva Diana , Santos Jorge , Pires Graça , Lisboa Maria , Prieto Isabel 
Published: March 2021

Abstract
Purpose: Amniotic membrane transplantation (AMT) has shown promising results as an antifibrotic agent in trabeculectomy. We aimed to evaluate the additional effect of AMT in M MC-augmented trabeculectomy .

Methods: This retrospective study analyzed the results of the first 12 postoperative months of glaucomatous eyes submitted to Moorfields Safer Surgery Trabeculectomy with MMC alone (non-AMT group) compared to MMC and AMT (AMT group). Both groups were compared in terms of intraocular pressure (IOP), number of antihypertensive medications and need for surgical reinterventions. Absolute and relative success rates 12 months after surgery were defined as IOP <18 mmHg, without and with the use of antihypertensive medications, respectively.

Results: The analysis included 51 eyes of 45 glaucoma patients (29 eyes in the non-AMT group and 22 in the AMT group). Mean IOP decreased from 24,72±5,11 mmHg and 26,86±10,62 mmHg preoperatively in non-AMT and AMT groups to 12,86±4,22 mmHg and 12,60±4,43 mmHg, respectively, at 12 months (p=0,84). Postoperative number of medications decreased significantly in both groups. Absolute success was seen in 71% of non-AMT eyes and 55% of AMT eyes (p=0,46) whereas relative success was obtained in 14% and 30%, respectively (p=0,55). Reinterventions were needed in 28% of the eyes (11 bleb injection/needling and 4 Ahmed tube implantation) in the non-AMT group and in 27% of the AMT group (10 bleb injection/needling and 1 Ahmed tube implantation) (p=0,89).

Conclusion: Trabeculectomy combined with MMC and AMT did not show better results than trabeculectomy with MMC alone.
Vibration Control of Nonlinear Three‐dimensional Marine Riser Model with Output Constraints
Authors: Wan Min , Yin Yanxia , Liu Jun , Guo Xiaoqiang 
Published: March 2021

Abstract
A typical three-dimensional flexible marine riser which is described by a distributed parameter system with several partial differential equations and ordinary differential equations is considered in this paper, we are aiming at limiting the top displacement of riser within restricted ranges. Appropriate boundary controls by integrating finite-dimensional backstepping technique with barrier Lyapunov functions are put forwarded to suppress the vibration of flexible riser under the external disturbance. The stability of the closed-loop system with the designed boundary control laws is proved by Lyapunov’s synthetic method without any discretization or simplification of the dynamic in the time and space when the initial conditions are satisfied. Furthermore, in order to illustrate the effectiveness of proposed controls laws, numerical simulation studies are carried.
3D-Fringe Pattern Coding and Recognition Using Plasmonic Sensing Circuit
Authors: Arumona Arumona Edward , Garhwal Anita , Youplao Phichai , Ray Kanad , Khunnam Wanchai , Yupapin Preecha 
Published: March 2021

Abstract
3D interference fringe pattern recognition using a plasmonic sensing circuit is proposed. The plasmonic sensing in the form of a panda ring comprises of an embedded gold grating at the microring center. WGM (whispering gallery mode) is observed at the microring center with suitable parameters. The dark soliton of 1.50µm wavelength excites the gold grating which leads to electron cloud oscillation and forms the electron densities where the trapped electrons inside the silicon microring are transported via wireless connection using WGM and cable connection. The spin-down |↓〉(|1〉) and spin-up |↑〉(|0〉) result from the electron cloud oscillation. By using the changes in gold lengths, the excited electron pattern recognition can be manipulated, where the values "0 and "1"' are useful for pattern recognition. The fringe patterns of the plasmonic interferometric sensor are recorded, which means that the novel 3D pattern recognition can be possibly implemented and used in many applications. Therefore, the plasmonic sensing circuit can be used to form the quantum code, quantum encryption, quantum sensor, and pattern recognition.
Identification of IFN-β Associated Genes Signature Predicting Overall Survival for Glioblastoma
Authors: Lijing Cheng , Meiling Yuan , Shu Li , Junjing Chen , Shupeng Zhong , jian zhou 
Published: March 2021

Abstract
Background: Brain glioblastoma (GBM) is the most common primary malignant tumor of intracranial tumors. The prognosis of this disease is extremely poor. While the introduction of IFN-β regimen in the treatment of gliomas has significantly improved the outcome of patients, the underlying mechanism remains to be elucidated. Materials and methods: mRNA expression profiles and clinicopathological data were downloaded from TCGA-GBM and GSE83300 data set from the GEO. Univariate Cox regression analysis and lasso Cox regression model established a novel four‐gene IFN-β signature (including PRDX1, SEC61B, XRCC5, and BCL2L2) for GBM prognosis prediction. Further, GBM samples (n=50) and normal brain tissues (n=50) were then used for real-time polymerase chain reaction (PCR) experiments. Gene Set Enrichment Analyses (GSEA) was performed to further understand the underlying molecular mechanisms. Pearson correlation was applied to calculate the correlation between the lncRNAs and IFN-β associated genes. A lncRNA with a correlation coefficient |R2| > 0.3 and P < 0.05 was considered to be an IFN-β associated lncRNA.Results: Patients in the high‐risk group shown significantly poorer survival than patients in the low‐risk group. The signature was found to be an independent prognostic factor for GBM survival. Furthermore, GSEA revealed several significantly enriched pathways, which might help explain the underlying mechanisms. Our study identified a novel robust four‐gene IFN-β signature for GBM prognosis prediction. The signature might contain potential biomarkers for metabolic therapy and treatment response prediction in GBM.Conclusions: Our study established a novel IFN-β associated genes signature to predict overall survival of GBM, which may help in clinical decision making for individual treatment.