bluuebunny/crossref_metadata_2025_split huggingface dataset:
Digital healthcare retail: role of presence in creating patients' experience
Authors: Sreejesh S. , Sarkar Juhi Gahlot , Sarkar Abhigyan 
Published: June 2021

PurposeThe purpose of this study is to empirically examine the impact of technology-enabled service co-creation on patients' service patronage behaviour in healthcare retailing. The first objective is to examine the mediating roles of spatial presence and co-presence in the relationship between technology enabled co-creation and service experience. The second objective is to investigate if healthcare service experience impacts patients' relationship value with hospitals and subsequent patronage intention.Design/methodology/approachData were collected from a sample of 516 customers of three leading hospitals in India during the social isolation period of COVID-19. The data were analysed using structural equation modelling.FindingsThe study results demonstrate that customers' favourably perceived technology-enabled co-creation generates feelings of spatial presence and co-presence in the technology-enabled platform. The feeling of presence enhances patients' health care service experiences which in turn predict their relationship value perceptions towards the healthcare service provider. Co-presence dominates as a mediator in terms of magnitude over spatial presence. The favourable value perception positively impacts patients' intention to come back to the same hospital.Research limitations/implicationsThe study uses cross-sectional data, which does not incorporate any temporal variations in the investigated relationships. The study does not account for differences in government vs. private undertakings of healthcare system.Practical implicationsThe findings envisage a digital healthcare retail system, where hospitals can enhance patients' perceptions of healthcare service experience, relational value and re-patronage intention, based on the digital mediated environment design elements, i.e. spatial presence and co-presence. As co-presence is a dominant factor, ensuring that human healthcare experts (rather than technology based e-service elements like chatbots) participate in healthcare service co-creation is of prime importance to provide enriching service experience to the patients.Originality/valueThe value of the research lies in extending the theories of presence, UTAUT and S-O-R to understand digital healthcare retailing, in order to identify the mechanism of how online co-creative platform can generate hospital patronage behaviour among patients through the serial mediation of presence, augmented service experience and relationship value.
Awareness and adoption of positive selection technology among yam farmers in West Africa
Authors: Asante Bright Owusu , Osei-Adu Jonas , Osei Kingsley , Ennin Stella Ama , Aighewi Beatrice , Opoku Monica 
Published: June 2021

PurposeThis paper aims to investigate how awareness influences the adoption of positive selection (PS) technology among smallholder yam farmers in West Africa. PS has the potential of increasing yield and reducing disease incidence and severity in yam production.Design/methodology/approachThis paper applies the average treatment effect (ATE) methodology to estimate the rates of awareness and adoption of the PS technology and associated factors using data from 678 smallholder seed yam farmers in Ghana and Nigeria.FindingsThe results indicate that the actual adoption rates of PS technology are 58 and 55%, while the potential adoption rates are estimated at 89.5 and 79.3% for Ghana and Nigeria, respectively, if the PS technology was fully disseminated. This leads to adoption gaps of 31.7 and 24.8%, respectively, for Ghana and Nigeria stemming from incomplete awareness of the PS among the population of yam growing farmers. The PS adoption is high among the educated young farmers who are members of farmer based organizations and participate in demonstrations.Practical implicationsPromotional efforts for enhancing awareness and adoption of PS should target educated youth willing to participate in field demonstrations and should focus on scaling up of PS technology to ensure quality farmer saved seed yams and enhance yam productivity in West Africa.Originality/valueThe introduction of PS in seed yam production is quite recent also its introduction to seed yam farmers in West Africa. Subsequently, a better understanding of what the adoption status would be should everyone in the population of yam farmers are aware of PS is vital for policy, research and development.
Factors influencing the smart supply chain innovation performance of commodity distribution enterprises: an investigation from China
Authors: Liu Weihua , Zhang Jiahui , Wang Siyu 
Published: June 2021

PurposeThis study explores the influencing factors affecting smart supply chain innovation (SSCI) performance of commodity distribution enterprises, and proposes the corresponding framework from the perspective of the application of technology to improve the SSCI performance and make up the research gap in this field.Design/methodology/approachA multi-case study method is adopted in this study. Four distribution commodity distribution enterprises A, B, C and D in China are chosen as case enterprises. The interviews with senior management team members are used to collect data. The combination of open coding and axial coding are used to process the data. By testing the reliability and validity, the theoretical framework is summarized.FindingsFirst, we find that the technology application cost inhibits SSCI and that the level of technology suitable for enterprise development will promote SSCI. Second, SSCI in structure, management and services can improve the performance and innovation ability of enterprises. Third, the quality of multi-channel integration and degree of customization around customer demand can significantly modify the above effects.Originality/valueCompared with previous studies, this study reveals for the first time the correlation between the SSCI performance and technology application, SSCI in structure, management and service, providing new ideas for relevant researches on SSCI, and providing new theoretical support for managers' decision-making related to SSCI.
Leveraging online behaviors for interpretable knowledge-aware patent recommendation
Authors: Du Wei , Yan Qiang , Zhang Wenping , Ma Jian 
Published: June 2021

PurposePatent trade recommendations necessitate recommendation interpretability in addition to recommendation accuracy because of patent transaction risks and the technological complexity of patents. This study designs an interpretable knowledge-aware patent recommendation model (IKPRM) for patent trading. IKPRM first creates a patent knowledge graph (PKG) for patent trade recommendations and then leverages paths in the PKG to achieve recommendation interpretability.Design/methodology/approachFirst, we construct a PKG to integrate online company behaviors and patent information using natural language processing techniques. Second, a bidirectional long short-term memory network (BiLSTM) is utilized with an attention mechanism to establish the connecting paths of a company — patent pair in PKG. Finally, the prediction score of a company — patent pair is calculated by assigning different weights to their connecting paths. The semantic relationships in connecting paths help explain why a candidate patent is recommended.FindingsExperiments on a real dataset from a patent trading platform verify that IKPRM significantly outperforms baseline methods in terms of hit ratio and normalized discounted cumulative gain (nDCG). The analysis of an online user study verified the interpretability of our recommendations.Originality/valueA meta-path-based recommendation can achieve certain explainability but suffers from low flexibility when reasoning on heterogeneous information. To bridge this gap, we propose the IKPRM to explain the full paths in the knowledge graph. IKPRM demonstrates good performance and transparency and is a solid foundation for integrating interpretable artificial intelligence into complex tasks such as intelligent recommendations.
Are low- and middle-income countries profiting from fast fashion?
Authors: Khurana Karan , Muthu S.S. 
Published: June 2021

PurposeIn the last two decades, the fashion value chain traveled to developing parts of the world. To these nations, it paved a path for socio-economic development initially but lately, the aftermath has costed more. This article visualizes the gains and losses of fast fashion to these countries.Design/methodology/approachAn in-depth systematic literature review was performed to analyze the secondary data from academic journals and reports from international organizations. The authors have compiled their empirical journeys in academia, research and industry from low- and middle-income countries (LMICs) based on Schon's (1983, 1990) theory of reflective practice. Further on, the article is structured using the value chain analysis (VCA) method which visualizes the aftermath of mass-producing fashion for the developed countries.FindingsIn this research it was found that LMICs have made substantial economic progress in the past two decades, however at a high social and environmental cost. It is the right time to find a balance between economic development and harm caused to the citizens of these nations.Originality/valueAt the moment the existing academic literature talks about unsustainable practices in the fashion sector around the world. This research precisely targets the LMICs where the aftermath is supposed to be much more severe. Further, it provides solutions and urges these nations to bring a substantial change throughout the value chain for a robust future.
Energy technological innovation and carbon emissions mitigation: evidence from China
Authors: Cheng Shuping , Meng Lingjie , Xing Lu 
Published: June 2021

PurposeThe purpose of this paper is to examine the effects of energy technological innovation on carbon emissions in China from 2001 to 2016.Design/methodology/approachConditional mean (CM) methods are first applied to implement our investigation. Then, considering the tremendous heterogeneity in China, quantile regression is further employed to comprehensively investigate the potential heterogeneous effect between energy technological innovation and carbon emission intensity.FindingsThe results suggest that renewable energy technological innovation has a significantly positive effect on carbon emission intensity in lower quantile areas and a negative effect in higher quantile areas. Contrarily, fossil energy technological innovation exerts a negative correlation with carbon emission intensity in lower quantile areas and a positive effect on carbon emission intensity in higher quantiles areas.Originality/valueConsidering that energy consumption is the main source of CO2 emissions, it is of great importance to study the impact of energy technological innovation on carbon emissions. However, the previous studies mainly focus on the impact of integrated technological innovation on carbon emissions, ignoring the impact of energy technological innovation on carbon emissions mitigation. To fill this gap, we construct an extended STIRPAT model to examine the effects of renewable energy technological innovation and fossil energy technological innovation on carbon emissions in this paper. The results can provide a reference for the government to formulate carbon mitigation policies.
Expanding mutational spectrum of HRAS by a patient with Schimmelpenning–Feuerstein–Mims syndrome
Authors: Luo Qi , Zhang Qin , Shen Jinwen , Guan Wenbin , Li Ming , Zhang Jia , Tan Zhen 
Published: June 2021

AbstractAs one of the epidermal nevus syndromes, Schimmelpenning–Feuerstein–Mims (SFM) is characterized by craniofacial nevus sebaceous (NS) and extracutaneous abnormalities (e.g., brain, eyes, and bone). Here, we report a case of a 4‐year‐old boy who presented with significant skin abnormalities (NS in the scalp, extensive epidermal nevus along Blaschko’s lines), ocular abnormalities (strabismus), central nervous system abnormalities (seizure and mental retardation), lymphatic dysplasia (chylous pleural and pericardial effusion), cardiac abnormalities (patent foramen ovale), urogenital system abnormalities (cryptorchidism, hypospadias), and a tumor predisposition (embryonal rhabdomyosarcoma). DNA samples from NS, rhabdomyosarcoma, and peripheral blood leukocytes were analyzed by next‐generation sequencing. A novel mutation in the HRAS gene (c.38G>T; p.Gly13Val) was detected in a mosaic state in NS, rhabdomyosarcoma, and peripheral blood leukocytes, with different ratio of heterozygous mutation (HRAS c.38G>T) of 39.90% (9412/23 588 reads), 73.03% (205 562/281 468 reads), and 14.16% (15 837/111 842 reads), respectively. By predicting the impact of the mutation on the biological function of protein, we found that the novel HRAS mutation (c.38G>T; p.Gly13Val) had the highest damaging scores among other HRAS mutations reported so far. This is the first reported SFM syndrome patient with novel mosaic HRAS mutation, which may help to expand the mutational spectrum of HRAS and better understand the role of HRAS in the disease.
Role of necroptosis in infection‐related, immune‐mediated, and autoimmune skin diseases
Authors: Liu Lulu , Tang Ziting , Zeng Yilan , Liu Yuanhong , Zhou Lu , Yang Shengbo , Wang Dan 
Published: June 2021

AbstractRegulated necrosis, also termed necroptosis, is another programmed cell death depending on a unique molecular pathway that does not overlap with apoptosis. Tumor necrosis factor and Toll‐like receptor family members, interferon, and other mediators are the factors that mainly cause necroptosis. Activating necroptosis by ligands of death receptors requires the kinase activity of receptor‐interacting proteins 1 and 3, and a mixed lineage kinase domain‐like protein, which is a critical downstream mediator of necroptosis. Increasing evidence has revealed that necroptosis does not only involve physiological regulation but also the occurrence, development, and prognosis of certain diseases, such as septicemia, neurodegenerative diseases, and ischemic–reperfusion injury. Many excellent documented systematic discussions of necroptosis and its role in various skin diseases. In this review, we summarize the molecular mechanism of necroptosis, as well as the current knowledge on the contribution of necroptosis, in infection‐related, immune‐mediated, autoimmune skin diseases, and malignant skin tumors.
Microbiome of juvenile corals in the outer reef slope and lagoon of the South China Sea: insight into coral acclimatization to extreme thermal environments
Authors: Qin Zhenjun , Yu Kefu , Chen Shuchang , Chen Biao , Liang Jiayuan , Yao Qiucui , Yu Xiaopeng , Liao Zhiheng , Deng Chuanqi , Liang Yanting 
Published: June 2021

SummaryEnvironmental conditions between the outer reef slope (ORS) and lagoon in tropical atolls are significantly different, but the variations of juvenile coral‐microbiomes in the two environments and their relationship with coral thermal acclimatization are poorly understood. We explored this issue based on local water conditions and the microbiome of juvenile corals in the ORS and lagoon in the central South China Sea. Coral‐symbiotic Symbiodiniaceae showed significant differences among coral species; Pocillopora verrucosa and Pachyseris rugosa in the ORS, and Acropora formosa in the lagoon were dominated by Durusdinium, but other corals were dominated by Cladocopium. Although A. formosa in the ORS were dominated by Cladocopium (C3u), they were dominated by Durusdinium (D1/D1a) and Cladocopium (C50) in the lagoon. Other coral species were both dominated by Cladocopium in the lagoon and ORS. The relative abundance of bacteria in the Deinococcus–Thermus was generally higher in the lagoon corals than in the ORS corals. Our study indicates that P. verrucosa, P. rugosa and Porites lutea may have high thermal tolerance based on the relatively high abundance of heat‐tolerant Durusdinium and Thermus scotoductus. Likewise, A. formosa in the lagoon may acclimatize to the thermal environment based on a high relative abundance of heat‐tolerant Durusdinium.
A rare suicide case involving fatal bleeding from varicose veins
Authors: Handlos Petr , Handlosová Klára , Klabal Ondřej , Uvíra Matěj 
Published: June 2021

AbstractThis case report deals with a sharp force suicide case, which may challenge the experience of many forensic pathologists as well as the studies published to date. An overview of the published cases shows that sharp force suicides account only for 1.6%–3% of all suicides and the self‐inflicted injuries are usually localized on the body parts easily accessible with one's hand including the neck, thorax, or upper extremities, as well as in locations of major vascular bundles or vital organs. Reported, however, is a case in which the victim relied on the knowledge of her medical condition and used a kitchen knife to incise her varicose veins, which resulted in fatal bleeding. The case is rare on a number of grounds: incision of varicose veins is rarely the method of choice in suicide cases, injuries of peripheral veins are rarely fatal, and so are injuries of isolated veins where no damage to arteries is suffered.
Nicotine Inhalation and Suicide: Clinical Correlates and Behavioral Mechanisms
Authors: Swann Alan C. , Graham David P. , Wilkinson Anna V. , Kosten Thomas R. 
Published: June 2021

Background and ObjectivesExtensive evidence links smoking and suicide independently of psychiatric diagnoses, but there are questions about the pathophysiology and specificity of this relationship. We examined characteristics of this linkage to identify potential transdiagnostic mechanisms in suicide and its prevention.MethodsWe reviewed literature that associated suicide with smoking and e‐cigarettes, including the temporal sequence of smoking and suicide risk and their shared behavioral risk factors of sensitization and impulsivity.ResultsSmoking is associated with increased suicide across psychiatric diagnoses and in the general population, proportionately to the number of cigarettes smoked per day. Rapid nicotine uptake into the brain through inhalation of conventional cigarettes, electronic cigarettes (e‐cigarette), or even second‐hand smoke can facilitate long‐term sensitization and short‐term impulsivity. Both impair action regulation and predispose to negative affect, continued smoking, and suicidal behavior. Intermittent hypoxia, induced by cigarettes or e‐cigarettes, synergistically promotes impulsivity and sensitization, exacerbating suicidality. Two other shared behavioral risks also develop negative urgency (combined impulsivity and negative affect) and cross‐sensitization to stressors or to other addictive stimuli. Finally, early smoking onset, promoted by e‐cigarettes in never‐smokers, increases subsequent suicide risk.Conclusion and Scientific SignificancePrevention or cessation of nicotine inhalation can strategically prevent suicidality and other potentially lethal behavior regardless of psychiatric diagnoses. Medications for reducing smoking and suicidality, especially in younger smokers, should consider the neurobehavioral mechanisms for acute impulsivity and longer‐term sensitization, potentially modulated more effectively through glutamate antagonism rather than nicotine substitution. (Am J Addict 2021;30:316–329)
Digital extension, price risk, and farm performance: experimental evidence from Nigeria
Authors: Oyinbo Oyakhilomen , Chamberlin Jordan , Abdoulaye Tahirou , Maertens Miet 
Published: June 2021

AbstractDespite decades of investment in agricultural extension, technology adoption among farmers and agricultural productivity growth in Sub‐Saharan Africa remain slow. Among other shortcomings, extension systems often make recommendations that do not account for price risk or spatial heterogeneity in farmers' growing conditions. However, little is known about the effectiveness of extension approaches for nutrient management that consider these issues. We analyze the impact of farmers' access to site‐specific nutrient management recommendations and to information on expected returns, provided through a digital decision support tool, for maize production. We implement a randomized controlled trial among smallholders in the maize belt of northern Nigeria. We use three waves of annual panel data to estimate immediate and longer term effects of two different extension treatments: site‐specific recommendations with and without complementary information about variability in output prices and expected returns. We find that site‐specific nutrient management recommendations improve fertilizer management practices and maize yields but do not necessarily increase fertilizer use. In addition, we find that recommendations that are accompanied by additional information about variability in expected returns induce larger fertilizer investments that persist beyond the first year. However, the magnitudes of these effects are small: we find only incremental increases in investments and net revenues over two treatment years.
Probiotic mixture reduces gut inflammation and microbial dysbiosis in children with atopic dermatitis
Authors: Yoon Wonsuck , Park Sang Hyun , Lee Jue Seong , Byeon Jung Hye , Kim Seung Hyun , Lim Jaehoon , Yoo Young 
Published: June 2021

AbstractBackgroundRecent data suggested that dysbiosis of the gut microbiome is associated with childhood allergic diseases. Oral administration of probiotic formulations may improve the severity of atopic dermatitis (AD) by restoring imbalanced gut microbiota and reducing intestinal inflammation in children.ObjectivesThe aim of this study was to investigate the effects of a probiotic mixture on the clinical severity of AD, gut inflammatory markers and alterations in microbiome dysbiosis in children with AD.MethodsA total of 25 subjects were enrolled in this study and administered with a mixture of probiotic strains consisting of Lactobacilli and Bifidobacteria for 4 weeks. The clinical efficacy of the probiotic mixture was assessed using SCORAD index and TEWL. Faecal calprotectin levels were measured as a marker for intestinal inflammation. The composition and diversity of the gut microbiome were analysed using 16S rRNA pyrosequencing.ResultsThe SCORAD (38.9 ± 17.2 vs 29.0 ± 15.4, P < 0.001) and TEWL (58.3 ± 12.5 vs 27.3 ± 8.7 g/m2/h, P = 0.028) were significantly decreased after 4 weeks administration of the probiotic mixture. The faecal calprotectin level (121.5 [27.7–292.9] vs 37.0 μg/g [12.6–108.9 μg/g], P = 0.038) was significantly decreased. The α‐diversity and composition of the gut microbiome were not significantly changed, but β‐diversity was increased after 4 weeks.ConclusionsThe oral administration of the probiotic mixture was effective in reducing clinical severity and intestinal inflammation in children with AD. Gut microbial diversity was slightly increased after administration of the probiotic mixture. The results of this study suggest that a probiotic mixture can alleviate AD by decreasing inflammation and modulating the gut microbiota in children with AD.
Editorial: tobacco use in functional dyspepsia—another smoking gun? Authors' reply
Authors: Talley Nicholas J. , Walker Marjorie M. , Agreus Lars , Andreasson Anna 
Published: June 2021

LINKED CONTENTThis article is linked to Talley et al and Woo & Andrews papers. To view these articles, visit https://doi.org/10.1111/apt.16372 and https://doi.org/10.1111/apt.16394