bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unterbrechungsfreie Versorgung
Authors: Lemme‐Henkel Jennifer 
Published: May 2021

AbstractDie unterbrechungsfreie Versorgung von Maschinen und Anlagen mit Druckluft, Sauerstoff, Stickstoff und weiteren technischen Gasen ist für produzierende Industrieunternehmen existenziell. Jeder Maschinenausfall kostet sofort richtig Geld. Dank der „kalten“ Pressverbindungstechnik für Rohrleitungen von Viega fallen die Stillstandzeiten bei Reparatur, Erweiterung oder bei Neuinstallationen aber deutlich kürzer aus als üblich. Mit für das jeweilige Medium angepassten Rohrleitungssystemen und entsprechenden Dichtelementen sind die Viega‐Systeme dabei für eine Vielzahl von Einsatzbereichen in der Industrie geeignet.
Eiszeit für Chemieriesen
Authors: Lutz Stefanie 
Published: May 2021

AbstractIn der Chemieindustrie ist eine absolut zuverlässige Kälteversorgung gefordert. Wie auch in solch hochsensiblen Umgebungen nachhaltig gekühlt werden kann, zeigt ein aktuelles Projekt von ENGIE Refrigeration: Bei einem deutschen Chemiekonzern garantieren am Standort Singapur fünf QUANTUM‐Power‐Kältemaschinen mit einer Kälteleistung von 25 Megawatt eine hohe Versorgungssicherheit – und reduzieren gleichzeitig die CO2‐Emissionen um 1.650 Tonnen pro Jahr.
MES und die Intralogistik
Authors: Heil Ulrich 
Published: May 2021

AbstractReibungslose Abläufe sparen Zeit, Geld, Nerven, steigern die Produktivität und sichern Wettbewerbsvorteile. Eine gut aufgestellte Intralogistik ist daher für alle Unternehmen wichtig, die Material einkaufen, produzieren, halbfertige oder fertige Produkte einlagern und diese anschließend versenden. Die dafür notwendige, produktionsnahe Logistik gehört zwar nicht zum Kern eines Manufacturing Execution Systems (MES), in der Praxis sind jedoch die Grenzen fließend. MES‐Installationen, die zumindest Teile der internen Logistik übernehmen, können durchaus sinnvoll sein. Je nach Anwendung sind als Ergänzung oder Alternative aber auch Warehouse Managementsysteme, ERP‐Systeme oder Mischformen, die sich die Arbeit teilen, die richtige Wahl. Um die passende Lösung für das eigene Unternehmen zu finden, müssen daher zunächst die individuellen Prozesse genau analysiert werden. Das kann durchaus zu einer Herausforderung werden. Externe Spezialisten, die herstellerunabhängig beraten, bieten in diesem Fall wertvolle Unterstützung.
Mischen und Gas geben
Authors: Cassens Cord 
Published: May 2021

AbstractIm Jahr 2016 konzipierte der dänische Landwirtschaftsbetrieb Rybjerggaard eine Biogasanlage, um die Selbstversorgung sicherzustellen und Energieeinsparungen zu ermöglichen. Die in den Faultürmen eingesetzte Rührtechnik bestehend aus klassischen Propellerwerken im oberen Bereich des Turms konnte die Bildung einer dicken Schwimmschicht nicht verhindern und fiel schließlich aus. Trotz Reparatur der Aggregate blieb das Problem bestehen, sodass sich die Verantwortlichen nach einer Alternative umsahen. Abhilfe schuf schließlich das GasMix‐System von Landia.
Kompakte Verpackungslösung
Authors: Ievolo Melanie 
Published: May 2021

AbstractDer neue Ecobulk MX 560 von Schütz ist ein besonders flacher IBC mit einem Nennvolumen von 560 Litern beziehungsweise 150 Gallonen. Somit eignet sich der neue Container bestens für Anwendungen, bei denen kleinere Gebinde von Vorteil sind, es jedoch parallel auf maximale Performance und höchste Qualität ankommt. Er kombiniert optimales Füllvolumen bei gleichzeitig geringer Containerhöhe mit einer bereits vielfach bewährten Bodengruppe. Sie entspricht denen der MX‐Typen mit 820, 1.000 und 1.250 Litern Fassungsvermögen. All diese Modelle der MX‐Linie sind somit kompatibel.
Die wiederkehrende Prüfung automatisieren
Authors: Janzer Thomas 
Published: May 2021

AbstractWiederkehrende Prüfungen bei Sicherheitseinrichtungen sind nicht nur von Sicherheitsstandards wie der IEC61511 vorgeschrieben, sondern sie helfen auch ungeplantem Anlagenstillstand vorzubeugen. Das Prinzip ist mit den TüV‐Prüfungen beim Auto vergleichbar. Die Prüfungen finden in anlagen‐ und geräteabhängigen Intervallen statt und sind erforderlich, um gefährliche unentdeckte Fehler im Betrieb aufzudecken. Allerdings verursachen solche Prüfungen manuellen Aufwand, binden viel Personal und sind zeitintensiv. Dank moderner Sicherheitssysteme und der "Digitalisierung" der Feldgeräteinformationen lassen sich Prüfabläufe jetzt weitgehend automatisieren, was in der Praxis deutliche Erleichterungen bringt und Einsparpotentiale erschließt.
IT‐Sicherheitsgesetz 2.0
Authors: Seiß Georg 
Published: May 2021

AbstractIm Zuge der Corona‐Krise haben wir ein Gespür dafür entwickelt, welche Konsequenzen die Verknappung von Ressourcen haben kann. Wie lässt sich also der Ausfall jener Anlagen und Systeme vermeiden, die zu nachhaltigen Versorgungsengpässen oder sogar zu einer Gefährdung der öffentlichen Sicherheit führen würden? Für diese sogenannten Kritischen Infrastrukturen (KRITIS) machen beispielsweise das IT‐Grundschutzkompendium, die IEC 62443 oder das IT‐Sicherheitsgesetz strenge Vorgaben, wie Sicherheitskonzepte systematisch anzuwenden sind. Für die automatisierte Produktion kommt einem durchdachten Daten‐ und änderungsmanagement eine immer größere Rolle zu, denn damit lassen sich viele dieser Anforderungen mit einer entsprechenden Lösung verhältnismäßig einfach umsetzen. Zudem kann eine optimierte Datensicherung laufende Kosten drastisch senken.
Residual alterations of cardiac and endothelial function in patients who recovered from Takotsubo cardiomyopathy
Authors: Zilberman Liaz , Zalik Adi , Fugenfirov Irina , Shimoni Sara , George Jacob , Goland Sorel 
Published: May 2021

AbstractIntroductionTakotsubo cardiomyopathy (TCM) is characterized by transient left ventricle dysfunction.HypothesisA residual cardiac and endothelial dysfunction is present in patients who recovered from TCM.MethodsIn this single‐center prospective study, patients with prior TCM were included and followed for 6.4 ± 1.6 years. All underwent comprehensive cardiac function assessment, including tissue Doppler imaging (TDI) and 2‐dimensional strain (2DS) echocardiography at their first visit. The number of circulating endothelial progenitor cells and levels of proangiogenic vascular endothelial growth factor (VEGF) and its receptor (VEGF‐R) were measured. All measurements were compared with healthy controls.ResultsForty‐two women (age 58. ±8.6 years, LVEF 58.1 ± 6.1%) comprised the TCM group. Patients post‐TCM had significantly lower early velocities E′ (6 (5.0–8.0) vs. 9 (7.0–11.0) cm/s, p = .001) by TDI and higher E/E′ ratio (p = .002), lower LV global average longitudinal strain (LGS) (−18.9 ± 3.5% vs. −21.7 ± 2.3%, p = .002) and RV LGS (−20.1 ± 3.9% vs. −23.4 ± 2.8%, p = .003) were evident. There was a trend toward a higher VEGF‐R (p = .09) along with decreased VEGF/VEGF‐R ratio representing inadequate VEGF production. In‐hospital mortality was not reported and only two non‐cardiac deaths occurred at long‐term follow‐up.ConclusionsAltered TDI and 2DS indices suggest residual biventricular myocardial injury in post‐TCM patients with the apparent LV function recovery. Inappropriate production of VEGF and VEGF‐R were observed, suggesting a possible underlying endothelial dysfunction in these patients.
Dental tray adhesives and their role as potential transmission medium for microorganisms
Authors: Schierz Oliver , Müller Henrik , Stingu Catalina Suzana , Hahnel Sebastian , Rauch Angelika 
Published: May 2021

AbstractObjectivesThis study aimed to evaluate the possible ability of dental impression tray adhesives to serve as a transmission medium for bacteria and fungi when reusable adhesive applicators are utilized.Materials and methodsTen flasks with tray adhesive were monitored over a period of 12 weeks during clinical use for contamination with bacteria or fungi. Adhesive fluid samples were cultivated on eight different culture media. All grown colonies were identified by using mass spectrometry (MALDI‐TOF). Isolates without reliable identification were either identified by Rapid ID 32 API‐STREP V3.0 or by sequencing the 16S rRNA genes.ResultsAfter 4 weeks, bacterial growth was detected on chocolate blood agar plates in five different samples. The bacterial species were identified as Staphylococcus warnerii, Staphylococcus epidermidis, Staphylococcus pasteuri, Ralstonia insidiosa, and Alloiococcus otitidis. After 8 weeks Streptococcus oralis grew on a blood agar plate. In all samples, no fungi were identified.ConclusionsThe disinfectant component of the tested tray adhesive seems to be effective. However, some bacteria survived in the flask for a clinically relevant time, which might result in a potential transmission to a new host.
Heterogeneous magnitude of immunological memory to SARS‐CoV‐2 in recovered individuals
Authors: Mazzoni Alessio , Maggi Laura , Capone Manuela , Vanni Anna , Spinicci Michele , Salvati Lorenzo , Tekle Kiros Seble , Semeraro Roberto , Pengue Luca , Colao Maria Grazia , Magi Alberto , Rossolini Gian Maria , Liotta Francesco , Cosmi Lorenzo , Bartoloni Alessandro , Annunziato Francesco 
Published: May 2021

AbstractObjectiveAlthough the adaptive immune response to SARS‐CoV‐2 has been characterised in the acute and early convalescent phase of the disease, few studies explore whether natural infection elicits long‐lasting immunological memory in recovered individuals. In this work, we aimed to assess the maintenance of immunological memory to SARS‐CoV‐2.MethodsWe evaluated the long‐term virus‐specific cellular and humoral immune response in the members of an Italian Serie A football team, who experienced a cluster of COVID‐19 in March 2020, which was strictly evaluated in the following months.ResultsOur results highlight a heterogeneous magnitude of immunological memory at 5 months after infection. Indeed, 20% of the subjects displayed a weak cellular and humoral memory to SARS‐CoV‐2, suggesting that they may be at higher risk of reinfection. In addition, a history of symptomatic COVID‐19 was associated with higher levels of SARS‐CoV‐2‐reactive CD4+ T cells and specific antibody levels than in asymptomatic individuals.ConclusionCollectively, these data demonstrate that immunity to SARS‐CoV‐2 is maintained five months postinfection even if the magnitude of response is heterogeneous among individuals. This finding suggests that some COVID‐19‐recovered subjects may benefit from vaccination.
GSK‐3β S9A overexpression leads murine hippocampal neural precursors to acquire an astroglial phenotype in vivo
Authors: Flor‐García Miguel , Ávila Jesús , Llorens‐Martín María 
Published: May 2021

AbstractThe addition of new neurons to the existing hippocampal circuitry persists in the adult dentate gyrus (DG). During this process, named adult hippocampal neurogenesis (AHN), adult hippocampal progenitor cells (AHPs) give rise to newborn dentate granule cells (DGCs). The acquisition of a neuronal lineage by AHPs is tightly regulated by numerous signaling molecules and transcription factors. In this regard, glycogen synthase kinase 3β (GSK‐3β) is a master regulator of the maturation of AHPs in vitro. Here we analyzed the cell‐autonomous effects of overexpressing a constitutively active form of GSK‐3β (GSK‐3β S9A) in AHPs in vivo. To this end, we stereotaxically injected a GSK‐3β S9A‐encoding retrovirus (GSK‐3β‐V5) into the DG of young adult C57BL6/J Ola Hsd female mice and studied the cell lineage acquisition, migratory and marker expression patterns, and the morphological maturation of the infected cells over time. Strikingly, GSK‐3β S9A‐transduced cells expressed glial fibrillary acidic protein (GFAP) and NG2, thereby acquiring an immature astroglial phenotype, which differed markedly from the neuronal phenotype observed in cells transduced with a control retrovirus that encoded GFP. Accordingly, the morphology and migration patterns of cells transduced by the two retroviruses are remarkably divergent. These observations support the role of GSK‐3β as a cornerstone that regulates the balance between new astocytes/neurons generated in the adult murine DG.
Alike and different: Associations between orthorexic eating behaviors and exercise addiction
Authors: Strahler Jana , Wachten Hanna , Stark Rudolf , Walter Bertram 
Published: May 2021

AbstractObjectiveSymptoms of exercise addiction, a state of compulsively engaging in intense exercise, and orthorexic eating attitudes, the obsession with eating only healthy foods, often occur together. It is assumed that some more general psychological traits underlie this association. Main aim of this report was to examine similarities and differences between orthorexic eating and addictive exercising.MethodSix hundred and eight individuals completed an online survey (mean age: 27.5, SD = 11.0 years; 76.5% women) measuring exercise addiction (Exercise Addiction inventory, EAI), orthorexic eating (Düsseldorfer Orthorexie Skala, DOS), personality domains (Big‐Five Inventory‐10), anxiety and depression (Hospital Anxiety and Depression Scale).ResultsCorrelations between the DOS and EAI were .43 in women and .62 in men. Structural equation models identified gender‐specific as well as behavior‐specific psychological correlates. Among women, anxiety correlated with both EAI and DOS. In addition, the DOS correlated with depression and neuroticism while the EAI correlated with conscientiousness. In men, both scales were associated with conscientiousness and the EAI also correlated with extraversion. Clusterability analysis provided no evidence for clusters based on DOS and EAI.DiscussionPresent results showed a substantial correlation between addictive exercising and orthorexic eating, however, coefficients were smaller than expected and appeared higher in men. Both behaviors shared few psychological traits (anxiety in women, conscientiousness in men) thereby questioning the assumption of a similar origin. Additionally, gender‐specific psychological correlates point to the need for different disease management approaches in women and men.
Including tree spatial extension in the evaluation of neighborhood competition effects in Bornean rain forest
Authors: Newbery David M. , Stoll Peter 
Published: May 2021

AbstractClassical tree neighborhood models use size variables acting at point distances. In a new approach here, trees were spatially extended as a function of their crown sizes, represented impressionistically as points within crown areas. Extension was accompanied by plasticity in the form of crown removal or relocation under the overlap of taller trees. Root systems were supposedly extended in a similar manner. For the 38 most abundant species in the focal size class (10–<100 cm stem girth) in two 4‐ha plots at Danum (Sabah), for periods P1 (1986–1996) and P2 (1996–2007), stem growth rate and tree survival were individually regressed against stem size, and neighborhood conspecific (CON) and heterospecific (HET) basal areas within incremented steps in radius. Model parameters were critically assessed, and statistical robustness in the modeling was set by randomization testing. Classical and extended models differed importantly in their outcomes. Crown extension weakened the relationship of CON effect on growth versus plot species’ abundance, showing that models without plasticity overestimated negative density dependence. A significant negative trend of difference in CON effects on growth (P2−P1) versus CON or HET effect on survival in P1 was strongest with crown extension. Model outcomes did not then support an explanation of CON and HET effects being due to (asymmetric) competition for light alone. An alternative hypothesis is that changes in CON effects on small trees, largely incurred by a drought phase (relaxing light limitation) in P2, and following the more shaded (suppressing) conditions in P1, were likely due to species‐specific (symmetric) root competition and mycorrhizal processes. The very high variation in neighborhood composition and abundances led to a strong “neighborhood stochasticity” and hence to largely idiosyncratic species’ responses. A need to much better understand the roles of rooting structure and processes at the individual tree level was highlighted.
Glucose patterns following alcohol and illicit drug use in young adults with type 1 diabetes: A flash glucose monitoring study
Authors: Pastor Adam , Conn Jennifer , Loh Margaret , O'Brien Casey L , Teng Jessie , Finch Sue , Collins Lisa , MacIsaac Richard J , Bonomo Yvonne 
Published: May 2021

AbstractIntroductionTo assess the effects of alcohol and illicit drug use in young adults (age 18–35) with type 1 diabetes (T1D) on flash glucose monitor sensor glucose (SG) readings.MethodsTwenty young adults with T1D were enrolled from a tertiary referral hospital outpatient department in Melbourne, Australia for a 6‐week prospective observational study using flash glucose monitoring (FGM). Glucometrics comparing substance using days (SUEDs) to those without substance use (non‐SUEDS) were analysed. The primary outcomes were the difference in mean SG values, its standard deviation and minutes/24‐h period out of range (SG <3.9 mmol/L or >10.0 mmol/L) between matched SUEDs vs non‐SUEDs. An interaction model with the primary effect of HbA1c on SG values was also performed.ResultsThere were no differences in the primary outcome measures between SUEDS and non‐SUEDs. However, there were differences in the regression coefficients for HbA1c and glucometrics between non‐SUEDs and SUEDs for mean SG, time out of range and time with SG > 10 mmol/L. This difference was also identified between non‐SUEDS and days of ≥40 g alcohol for mean SG.ConclusionsWhile there was no difference between glucometrics for SUEDs and non‐SUEDs on primary outcomes, HbA1C was found to be a less reliable predictor of glucose patterns in the 24‐h period following substance use than control days. Young adults with T1D need to monitor and respond to their glucose levels following substance use and engage in harm minimisation practices irrespective of baseline glucose control.
Development of a method for calculating the transmission‐line constants of a three‐phase enclosure‐type gas insulated bus taking the proximity effect into account
Authors: Tanaka Yohei , Yonezawa Rikido , Noda Taku 
Published: May 2021

AbstractAccurately calculating the transmission‐line constants of underground cables and gas insulated bus (GIB) is important for various types of power system simulations. When calculating the transmission‐line constants of a three‐phase enclosure‐type GIB, the Cable Constants supporting routine of EMTP is usually used. However, this routine could cause numerical errors, since the proximity effect is ignored for the calculation of series impedances and shunt admittances. In this paper, a method for calculating the transmission‐line constants of a three‐phase enclosure‐type GIB considering the proximity effect is proposed. Then, series impedances and shunt admittances are accurately calculated by the method of moments with a surface admittance operator (MoM‐SO) and method of moments (MoM), respectively. In this paper, the proposed method is verified by experiments using the small‐scale model of a three‐phase enclosure‐type GIB. Calculated results obtained by the proposed method agree well with the measured results.
Study on cyber‐security for IoT edge utilizing pattern match accelerator
Authors: Kashiyama Masamori , Kashiyama Reo , Seki Hiroto , Hosono Hiroyuki 
Published: May 2021

AbstractA malware detection algorithm that can be embedded in IoT edge computing is proposed in this study and validated using an emulator. This algorithm, with a pattern match accelerator, reduces the computing cost while maintaining a relatively high detection accuracy. For autonomous driving, complicated IoT edge computing must have a huge amount of embedded program codes. In such a situation, the invasion of malware can lead to compromised cybersecurity. In this study, a pattern match accelerator is implemented for such issues, thereby offering IoT edge computing that detects malware automatically. Edge computing is designed to apply simply structural level analysis algorithms using HLAC mask pattern. We developed a pseudo‐emulator system environment and conducted performance confirmation of the proposed technique using 641 chosen samples from six types of malware families. The algorithm's efficiencies demonstrated an identification performance of approximately 80%. In comparison to characteristic extraction using AI, the computing cost was reduced and these processes enable edge computing with high cybersecurity features.
Serum creatinine and cystatin C‐based estimates of glomerular filtration rate are misleading in acute heart failure
Authors: Swolinsky Jutta S. , Nerger Niklas P. , Leistner David M. , Edelmann Frank , Knebel Fabian , Tuvshinbat Enkhtuvshin , Lemke Caroline , Roehle Robert , Haase Michael , Costanzo Maria Rosa , Rauch Geraldine , Mitrovic Veselin , Gasanin Edis , Meier Daniel , McCullough Peter A. , Eckardt Kai‐Uwe , Molitoris Bruce A. , Schmidt‐Ott Kai M. 
Published: May 2021

AbstractAimsWe aimed to test whether the endogenous filtration markers serum creatinine or cystatin C and equation‐based estimates of glomerular filtration rate (GFR) based on these markers appropriately reflect changes of measured GFR in patients with acute heart failure.MethodsIn this prospective cohort study of 50 hospitalized acute heart failure patients undergoing decongestive therapy, we applied an intravenous visible fluorescent injectate (VFI), consisting of a low molecular weight component to measure GFR and a high molecular weight component to correct for measured plasma volume. Thirty‐eight patients had two sequential GFR measurements 48 h apart. The co‐primary endpoints of the study were safety of VFI and plasma stability of the high molecular weight component. A key secondary endpoint was to compare changes in measured GFR (mGFR) to changes of serum creatinine, cystatin C and estimated GFR.ResultsVFI‐based GFR measurements were safe and consistent with plasma stability of the high molecular weight component and glomerular filtration of the low molecular weight component. Filtration marker‐based point estimates of GFR, when compared with mGFR, provided only moderate correlation (Pearson's r, range 0.80–0.88, depending on equation used), precision (r2, range 0.65–0.78) and accuracy (56%–74% of estimates scored within 30% of mGFR). Correlations of 48‐h changes GFR estimates and changes of mGFR were significant (P < 0.05) but weak (Pearson's r, range 0.35–0.39). Observed decreases of eGFR by more than 15% had a low sensitivity (range 38%–46%, depending on equation used) in detecting true worsening mGFR, defined by a >15% decrease in mGFR.ConclusionsIn patients hospitalized for acute heart failure, serum creatinine‐ and cystatin C‐based predictions performed poorly in detecting actual changes of GFR. These data challenge current clinical strategies to evaluate dynamics of kidney function in acute heart failure.