bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clear Cell Carcinoma Of The Ovary: An Experience From A Regional Cancer Centre In Odisha.
Authors: Nayak Dr. Bhagyalaxmi , Sukesh Dr. Neethu , Mohapatra Dr. Manoranjan , Mohapatra Dr. Janmejay , Kumar Padhy Dr.Ashok , Parija. Dr.Jita 
Published: November 2021

Background: Clear cell carcinoma of the ovary (CCCO) shows unique clinical features. There is a remarkable difference in incidence among different ethnic populations. The reasons for these differences in incidence around the world are not known.
Aim and objectives: To evaluate the clinical characteristics of patients with CCCO and to determine the impact of the stage of the disease and the extent of surgery on the prognosis of those patients.
Materials and methods: A retrospective analysis of the cases of clear cell carcinoma of the ovary that were operated in the regional cancer centre, Cuttack, from January 2009 to December 2018, was performed to evaluate the clinical characteristics and prognostic factors of the patients.
Results: During this study period, the incidence of CCCO was found to be 1.92%. The most common age group was 40–50 years (mean age of 44.7 years). The most common modes of presentation were abdominal distention and pain in the abdomen. Most of the cases in this study belonged to stage III C (65%), making it the most common stage in this group. 20% of the patients within the study group were nulliparous and 35% were menopausal in status.40% of the tumours were >15 cm in size. Almost 28% were lymph node positive. None in stage I had positive lymph nodes. All the cases in stage III were positive for lymph nodes. So, in stage III, 38.5% were positive for lymph nodes. 17/20 had some form of chemotherapy, of which 45% had NACT. Survival curves differ significantly between the early and advanced stages of the disease. A trend of survival benefit is seen with complete cytoreduction.
Conclusion: There is a need for data regarding the incidence and specific clinicopathologic behaviour of clear cell carcinoma of the ovary in the Indian population. This is an attempt to compile the data from a single tertiary institute in eastern India over the past 10 years. This is a rare tumour and the chances of missing data are well accepted. The survival advantage of early-stage-diagnosed patients over late-stage patients is tremendous and hard to ignore. Combining the fact that clear cell carcinomas are associated with precancerous lesions like atypical endometriosis and atypical adenofibroma, there may be scope for screening. The mutational changes leading to malignancy in these precancerous lesions also need to be refined. As stated, complete cytoreduction is the key to survival advantage and the need for referral to a centre with proper expertise for the same needs to be emphasized.
ЗОЛОТО В РУДАХ ЗОЛОТО-КОЛЧЕДАННОГО МЕСТОРОЖДЕНИЯ АБЫЗ (ЦЕНТРАЛЬНЫЙ КАЗАХСТАН)
Authors: Мазуров Алексей Карпович , Николаева Анастасия Николаевна , Рудмин Максим Андреевич , Якич Тамара Юрьевна , Рубан Алексей Сергеевич , Байболова Шынар Жуматаевна 
Published: November 2021

Ссылка для цитирования: Золото в рудах золото-колчеданного месторождения Абыз (Центральный Казахстан) / А.К. Мазуров, А.Н. Николаева, М.А. Рудмин, Т.Ю. Якич, А.С. Рубан, Ш.Ж. Байболова // Известия Томского политехнического университета. Инжиниринг георесурсов. – 2021. – Т. 332. – № 11. – С. 78-88
Актуальность исследования. В Чингиз-Тарбогатайской структурно-формационной зоне известно более 20 золото-колчеданных месторождений. Все месторождения объединяет одна проблема: при обогащении руд значительная часть золота переходит в «пиритный» концентрат и теряется вместе с «хвостами». В целях увеличения извлечения золота нами был детально изучен минеральный состав руд наиболее представительного золото-колчеданного месторождения Абыз. Установлено, что значительная часть золота на месторождении представлена минералом электрумом, который заполняет микротрещины в пирите и халькопирите. При разработке технологической схемы извлечения золота, вероятно, данному факту не было уделено должного внимания, так как считалось, что золото в пирите представлено самородным золотом. Цель: изучить текстурно-структурные особенности руд, а также установить минеральную форму нахождения золота в рудах месторождения Абыз и его связь с основными сульфидными минералами (пирит, халькопирит, галенит и сфалерит). Методы исследования включали изучение состава горных пород и руд с использованием минералогического, петрографического, минераграфического и геохимического анализов. Результаты. По структурно-текстурным свойствам на месторождении выделены вкрапленные и сплошные руды. Установлено, что основное количество золота, ассоциирующееся в основном с пиритом и редко халькопиритом, связано со сплошными рудами и представлено в минеральной форме. Золотая минерализация сопряжена с процессами березитизации; отложение минералов Au происходило в рудную стадию минералообразования и связано с золото-сульфидной и золото-теллуридной ассоциациями. Преобладающим минералом является электрум AgAu, в меньшей степени диагностируется самородное золото Au и единично обнаружен петцит Ag3AuTe2 с калаверитом AuTe2. Доминирующими минералами- концентраторами в рудах являются такие сульфиды, как пирит и халькопирит. Причину потери большей части золота в результате флотации можно объяснить тем фактором, что низкопробный золотосодержащий минерал электрум AgAu является господствующим.
Tensión creciente y Japón: Asia del Este en la década de 2010
Authors: Murakami Yusuke 
Published: November 2021

Este artículo analiza la situación cada vez más tensa de Asia del Este en la década de 2010 y los desafíos del Japón frente a dicha situación. A más de treinta años de la caída del Muro de Berlín,el orden y el statu quo de la segunda mitad del siglo pasado, han estado fuertemente desestabilizados tanto a escala global como en diversas partes del mundo. Asia del Este, dondese ubica Japón, es la región donde la mencionada dinámica mundial se ha presentado más agudamente, y en los últimos años, junto con el Medio Oriente, se ha convertido en un eventual «polvorín del mundo». Históricamente, Asia no ha alcanzado un nivel comparable al de Europa en lo concerniente a la institucionalización del orden regional entre los países componentes. El status quo precario de la posguerra ha sido convulsionado profundamente en este siglo. La incoherente posición diplomático-estratégica de Estados Unidos ha permitido el expansionismo de la China emergente, mientras Corea del Sur, cabeza de puente de la alianza diplomático-estratégica de la superpotencia en la región de la posguerra, se ha acercado más bien a China y Corea del Norte. Frente a la tensión continuamente creciente, Japón encara ahora más que nunca el desafío de romper la «inercia» de la posguerra para llegar a definir su rol político en la región y el mundo con miras a la construcción de un nuevo orden regional en mediano y largo plazo.
Biden y América Latina. Desafíos regionales para la política exterior estadounidense
Authors: Quispe Robles Javier Luciano 
Published: November 2021

¿Cuáles son los desafíos que enfrenta la política exterior de Joe Biden en América Latina? El presidente nortemericano ha prometido abrir una nueva etapa en las relaciones con los países latinoamericanos luego de cuatro años de una política exterior unilateral e impredecible de Donald Trump. Sin embargo, existen procesos en marcha en América Latina que imponen condiciones importantes para la política exterior estadounidense: procesos de autocratización en varios países de la región, una política exterior autónoma y competitiva de parte de las potencias regionales latinoamericanas y la creciente presencia de China en la región. El artículo discute cómo estos procesos configuran la política regional latinoamericana y qué desafíos representan para la amplia agenda que tiene Biden para la región, que va desde asuntos ambientales, migración, corrupción, derechos humanos, entre otros. Para ilustrar el argumento, se analiza la relación de Estados Unidos con países particulares a la luz de acontecimientos recientes. Así, el artículo busca contribuir con la discusión sobre factores que inciden en la política exterior y en específico en la relación de Estados Unidos con América Latina.
Hidropolítica en las zonas áridas y semiáridas de los Andes de América del Sur
Authors: De Cossío Klüver Manuel 
Published: November 2021

De acuerdo con el conocimiento convencional es probable que la competencia interestatal por acceder a las escasas fuentes de agua dulce planetarias se convierta en una de las principales preocupaciones de los gobiernos y la población mundial en las próximas décadas. De cumplirse esa predicción, se podrían incrementar las tensiones ya existentes entre los Estados cuando seañada una competencia más intensa por los recursos hídricos ubicados en sus fronteras.Estas tensiones se harían más agudas en zonas áridas o semiáridas, como los Andes y la costa del Pacífico Sur, en donde existe una escasez crónica de agua dulce al igual que estrés hídrico, donde el retroceso de los glaciares y las presiones que se ejercen sobre los limitados recursos hídricos existentes magnifican el panorama de escasez general y, por ende, la tensión hídrica. Este artículo es parte de un estudio sobre las tensiones hídricas emergentes del uso y gestión de recursos hídricos transfronterizos en zonas áridas y semiáridas, así como sobre su impacto en la seguridad de los Estados que comparten cursos de agua internacionales. En este texto se utilizará el caso del sistema hidrográfico del Silala, ubicado en la puna del desierto de Atacama, con la finalidad de analizar los factores políticos que podrían desencadenar conflictos hídricos, así como dificultar la adopción de acuerdos cooperativos.
La congelación de las líneas de base y de los límites marítimos de los Estados insulares en riesgo de perder la totalidad de sus respectivos territorios debido al aumento en el nivel del mar ocasionado por el cambio climático
Authors: Velásquez Barrionuevo Alejandro José 
Published: November 2021

El presente artículo presenta la problemática actual del hundimiento de los espacios terrestres de determinados Estados insulares debido al aumento en el nivel del mar ocasionado por el cambio climático. Dicha problemática motivó la aprobación del tema «La elevación del nivel del mar en relación con el derecho internacional», en el programa de trabajo de la Comisión de Derecho Internacional de las Naciones Unidas, en particular respecto al ámbito de la condición de Estado. Se analizan las implicancias jurídicas del hundimiento total del espacio terrestre conforme al derecho internacional actual verificando que la final es la pérdida de la condición de Estado. A fin de dar solución a la problemática jurídica planteada, se propone la aplicación de una ficción jurídica por la cual se consideren congeladas las líneas de base de los Estados en riesgo, la cual ya fue presentada como una cuestión a estudiar en el ámbito antes mencionado por la Comisión de Derecho Internacional.
La intervención de terceros Estados ante la Corte Internacional de Justicia: identificando criterios jurisprudenciales para la aceptación o denegación de las solicitudes
Authors: Roca Calderón Josselyn 
Published: November 2021

Existen tres supuestos posibles de intervención de terceros Estados en las controversias ante la Corte Internacional de Justicia. La intervención por interés de orden jurídico y la intervención por la interpretación de una convención se encuentran estipuladas en el Estatuto de la CIJ, pero la intervención por necesidad de consentimiento de una parte indispensable ha sido establecida en la jurisprudencia del referido tribunal. Dentro de este artículo se detallará cada supuesto, así como los lineamientos y/o criterios establecidos por la propia CIJ, los cuales han dotado de contenido a los conceptos establecidos en sus disposiciones, ya sea en el Estatuto o en su Reglamento. Para estos efectos, se analizará su jurisprudencia en casos con solicitudes de intervención a fin de identificar denominadores comunes en sus pronunciamientos.
Sugar Intake and Cancer: A Literature Review
Authors: Dewi Nikmah Utami , Diana Rian 
Published: November 2021

ABSTRACTBackground: Cancer is the second leading cause of death after heart disease globally (total death 9.6 million). Cancer prevalence is increasing in Indonesia from 1.4 per 1000 people in 2013 to 1.79 per 1000 people in 2018. Diet is linked with cancer prognosis, particularly carbohydrate intake which stimulates insulin signals that can be potent mitogens.Purpose: This literature review aims to examine sugar intake and cancer incidence.Method: This literature review (traditional review) using the keywords “cancer”,” sugar”, “carbohydrate”, “insulin” and “hyperinsulinemia” in the Sciencedirect database and Google search engine. The inclusion criteria were peer-review articles or documents from credible national and international institutions, the literature uses English or Bahasa (Indonesian Language). The exclusion criteria were that the literature had similar content or redundant with other literature.Result: Sugar increases insulin resistance which enhances the levels of bioactive IGF-I that contribute to raising the risk of cancer. Prolonged hyperinsulinemia reduces the production of growth-promoting factors such as IGFBP-1 and IGFBP-2 which normally bind to and inhibit the action of IGF-I with resultant increases in the levels of free, bio-active IGF-I, and concomitant changes in the cellular environment that favor cancer development, proliferation, and metastatic cancer cells.Conclusion: The mechanism of insulin and IGF-1 stimulate and accelerate cancer cell proliferation may explain the relationship between sugar intake and cancer incidence. Adopting a balanced diet, changing or decreasing sugar intake with healthier food coupled with increased physical activity reduces the risk of cancer.
THE EFFECT OF INTERVENTION PROGRAMS ON HOW TO WORK COMPLAINTS IN MECHANICAL WORKERS IN HEAVY EQUIPMENT COMPANIES
Authors: Ilyas Muhammad , Soffiudin Muhammad , Adi Nuri Purwito , Sulistomo Astrid , Kekalih Aria 
Published: November 2021

ABSTRACTLow back pain (LBP) is experienced by almost everyone during his life, and data in Indonesia ranged from 3-17% based on hospital records. LBP can occur due to awkward body postures and manual handling during working and need intervention to reduce complaints. This study to know intervention to reduce risk at ergonomic can induce LBP. This study uses a quasi-experimental design using control with a sample of 35 in each group. The intervention program monitoring was carried out by the SHE team at the work site based on conducting weekly observations regarding workers doing awkward work postures and manual handling activities and ensuring that mechanical workers receive ergonomics training. After one year of the intervention program, the data collection was carried out using a questionnaire to find out the changes in the length of the squat position, bending position, and manual handling activities in both groups. Significant differences between the two groups were obtained in the long work category with squat posture with p-value <0,001, bent posture with p-value 0.001, and a non-significant difference were found in the manual handling category with a p-value of 0.614. The intervention program can change manual handling in the intervention group 3.6 times at work duration more than 1 hour in a squatting position and decrease in the length of bending position more 1 hour by 1.4 times compared to control. Keywords: ergonomic training, squatting position, bending position, manual handling.
Default Negation as Explicit Negation plus Update
Authors: Kahle Reinhard 
Published: November 2021

We argue that under the stable model semantics default negation can be read as explicit negation with update. We show that dynamic logic programming which is based on default negation, even in the heads, can be interpreted in a variant of updates with explicit negation only. As corollaries, we get an easy description of default negation in generalized and normal logic programming where initially negated literals are updated. These results are discussed with respect to the understanding of negation in logic.
Nano-Texturing of Hydrocarbon Reservoirs with Omniphobic Nanoparticles to Mitigate Liquid Phase Trapping
Authors: Sayed Mohammed , Saini Rajesh , Ow Hooisweng 
Published: November 2021

Abstract
Gas reservoirs contain substantial amounts of natural gas and, in some cases, associated high API liquid hydrocarbons. Condensation of heavy hydrocarbons, especially in the area closer to the wellbore, occurs as a direct result of the decline in reservoir pressure. This hydrocarbon condensate, and in some cases water, tends to accumulate in the pore space and form a liquid bank. This liquid bank will result in a reduction in gas relative permeability and overall reduction in the well's productivity. This paper illustrates the synthesis and utilization of surface modified silica nanoparticles to mitigate the liquid banking phenomenon in gas reservoirs.
Silica nanoparticles (S-NPs), of different sizes, were synthesized using the Stöber process. The impact of the nanoparticle size and degree of functionalization with different hydrophobic and omniphobic groups on altering the rock wettability properties to mitigate liquid banking in gas reservoirs were studied. The S-NPs (of sizes between 50-400 nm) were functionalized with various linear and branched fluoroalkyl groups, terminal amine, and epoxy groups. The particle size of surface modified silica nanoparticles was determined using dynamic light scattering (DLS). The performance of the surface modified silica nanoparticles was evaluated through measuring surface charge, change in contact angle, and by performing core flow experiments at reservoir conditions.
A glass slide dip coated with 135 nm surface modified silica nanoparticles solution derivatized with terminal amine and perfluoroalkyl group provided a contact angle of 120° and 83° with water and decane, respectively. The contact angle can be tailored by changing the amount of amine and perfluoroalkyl concentrations on the particle surfaces. A contact angle of around 90° indicates a nonwetting neutral surface that results in minimizing capillary pressure and enhancing mobility of both hydrocarbon and water liquid phases. Using core flow studies and by estimating the improvement in gas and liquid relative permeabilities, surface modified silica nanoparticles treatment demonstrated a comparable performance to commercially available solutions at 1/5 the treatment volume. The surface modified silica nanoparticles sustained its performance indicating a stable and permanent coating on the rock surface.
The silica nanoparticles functionalized with fluoroalkyl group, terminal amine and epoxy can be directly pumped without the need for a pretreatment of the rock surface. This results in less complexity when it comes to the field operation. The dual- functionalized silica nanoparticles were found to be effective in changing the rock surface wettability to neutral or nonwetting, thereby providing a potential solution to liquid banking problem in gas reservoirs.
Fate of Emulsifier in Invert Emulsion Drilling Fluids: Hydrolysis and Adsorption on Solids
Authors: Khramov Dimitri , Barmatov Evgeny 
Published: November 2021

Abstract
Emulsifier concentration in SBM is an important factor of drilling fluid stability. Proper concentration of amidoamine emulsifier is imperative for controlling low fluid loss and maintaining emulsion stability. This study investigates the physical and chemical interactions between emulsifier and other additives and describes the processes by which emulsifier is depleted from the drilling fluid. Three main pathways of emulsifier consumption are identified: emulsifier adsorption on solids found in drilling fluids and low gravity solids (LGS), chemical degradation, and to stabilize the invert emulsion.
Design of experiments model and analytical procedure based on 1H NMR (nuclear magnetic resonance) spectroscopy was used to quantify the required emulsifier concentration in Non-Aqueous Fluid system (NAF). Additionally, model systems were used to estimate the excess of emulsifier, evaluate the emulsifier losses due to alkaline hydrolysis at elevated temperature, and measure adsorption of emulsifier on barite and various LGS types. Calculations for emulsifier depletion based on model systems were correlated to performance of formulated drilling fluids for verification.
Typical emulsifier requirement in high performance NAF is 8-12 pounds per barrel (ppb). Majority of the emulsifier is adsorbed on weighting agents (barite) and rheology modifiers (clays), which are used to formulate NAF, that contribute to their effective dispersion in the solution and control fluid rheology. The adsorption process is found to be sensitive to the emulsifier concentration, solids mineralogy, wetting agent and temperature. Analytical Langmuir-Freundlich isotherm was used to describe adsorption data and estimate the adsorption capacity of the system. The emulsifier degradation pathway is another important factor of emulsifier consumption; however, emulsifier degradation at 250°F is not significant. While NAF are generally run ‘rich’ to mitigate depletion and maintain fluid stability, adsorption onto minerals will become an issue especially at high LGS concentration.
These results will be greatly beneficial in the further development of NAF drilling fluid formulations and will assist field engineers in understanding the effect excess emulsifier will have on the drilling fluid and enable them to more effectively control the fluid properties under variations in emulsifier and LGS concentration during drilling.