bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modeling Scientometric Indicators Using A SDMX Ontology
Authors: Rodríguez Víctor Iván López , Ceballos Hector G. 
Published: September 2021

Abstract
Scientometrics is the field of study and evaluation of scientific measures such as impact of research papers and academic journals. It is an important field because nowadays different rankings use key indicators for university rankings and universities themselves use them as Key Performance Indicators (KPI). The purpose of this work is to propose a semantic modeling of scientometric indicators using the ontology Satistical Data and Metadata Exchange (SDMX). We develop a case study at Tecnologico de Monterrey following the Cross-Industry Standard Process for Data Mining (CRISP-DM) methodology. We evaluate the benefits of storing and querying in a Graph Database (Neo4j) the linked data produced by our approach.
Raptors of A Neotropical City: Diversity And Habitat Relationships Along An Urbanization Gradient
Authors: Martín-Cruz Miguel Ángel San , Villegas-Patraca Rafael , Martínez-Gómez Juan Esteban , Inzunza Ernesto Ruelas 
Published: September 2021

Abstract

Urbanization involves changes in landscape terrain, hydrology, and vegetation. These changes allow some wildlife species to thrive in cities while blocking others. We analyzed how a gradient of urbanization in the city of Xalapa could have a filtering effect that prevents some raptors from occurring or effectively use the most urbanized areas, and where such filtering effects occur. We selected 6 habitat variables that could predict the detection and occupation of raptors along the urban gradient. We conducted direct observations and call-broadcast surveys to estimate relative abundance, richness, and diversity of raptors from June 2019–February 2020. We visited 20 sites during three seasons, from dawn–11:00 and 18:00–23:00 h. We obtained 201 individual records of 14 species. The best-preserved part of the gradient (< 7.7% urban cover) had the highest species diversity, while the 4th category along the gradient (53.9% urban cover) had the lowest, suggesting that at this level of urbanization an abrupt filtering effect occurs on the raptor community. The proportion of exotic/native plant species was the best detection predictor for most of the diurnal species and Ciccaba virgata. The proportion of urban relative to green area was negatively associated with the occupation of Accipiter cooperii and Rupornis magnirostris. Our results suggests that this Neotropical city effectively acts as a filter for most species, with only 4 raptors able to use or occupy most of the urban gradient. Our work represents a critical first step towards understanding how the process of urbanization influences a raptor community.
Aqualabyrinth – A New Enrichment for Laboratory Zebrafish Under Analysis for Future Production
Authors: Therrien Dorothee , Dodelet-Devilliers Aurore 
Published: September 2021

Abstract
In the field of laboratory animals, there have been considerable improvements in environmental enrichment for mammalian species, but little remains available for aquatic species, in particular fish. Recent publications have shown benefits in providing laboratory Zebrafish (Danio rerio) certain types of enrichments, such as substrate and plants. This research article proposes a novel tank enrichment called the Aqualabyrinth, and the benefit of its use in laboratory Zebrafish. While the enrichment won 3rd place at the 2020 Janet Wood Innovation Award (JWIA) competition, the Aqualabyrinth is not yet available on the market. This novel enrichment proposes similar if not more qualities than current aquatic enrichments commercially available. More specifically, its ease of usage, maintenance, and modular configuration options make it an ideal choice for Laboratory fish tanks. Results showed interaction on average up to 10.5 per 3 fish within a 30 second test interval versus 6.25 per 3 fish within 30 seconds interval for a mouse igloo. With the additional benefits highlighted in this study, the Aqualabyrinth proves to be an efficient and practical environmental enrichment option, pending collaboration with interested manufacturers.
Astrocytes in the external globus pallidus coordinate flexibility of action strategy
Authors: Hong Sa-Ik , Kang Seungwoo , Song Minryung , Yang Minsu , Baker Matthew , Kang Shinwoo , Lee Jeyeon , Lee Sang Wan , Choi Doo-Sup 
Published: September 2021

Abstract
The external globus pallidus (GPe) is an integrative hub and gateway for behavioral flexibility in reward-related behaviors. However, it remains unknown whether enriched astrocytes in the GPe guide behavioral flexibility. Here, we trained mice to exhibit goal-directed and habitual reward-seeking behaviors using the behavior tasks with effort- and time-based reward delivery, respectively. Then, we examined the temporal dynamics of GPe astrocytes during goal-directed and habitual learning. Overall, GPe astrocytes were substantially silenced during habitual learning compared to goal-directed learning. In the timescale of action events, GPe astrocyte activities were increased immediately after termination of reward-taking behavior before the following action. However, during habitual learning, the increase of astrocyte activity was not evident. Moreover, support vector machine (SVM) analysis demonstrated that GPe astrocytes dynamics predicted whether mice perform goal-directed or habitual behaviors. Interestingly, chemogenetic activation of GPe astrocytes, which dampened GPe neuronal firings and habitual behaviors, exhibting goal-directed behaviors. Strikingly, brief and repeated attentional stimulations recapitulated the effect of chemogenetic activation of GPe in intervening the habitual reward-seeking behaviors with increased GPe astrocyte activities. Our findings reveal a novel insight that increasing GPe astrocytic activities attenuates habitual behavior and improves behavioral flexibility, which may provide a potential therapeutic target for decision-making-related disorders, such as obsessive-compulsive disorder and addiction.
A Memetic Algorithm for the Inventory Routing Problem
Authors: Sakhri Mohamed Salim Amri , Tlili Mounira , Korbaa Ouajdi 
Published: September 2021

Abstract
In this paper, we investigated an Inventory Routing Problem (IRP) with deterministic customer demand, in a two-tiered supply chain. The supply chain network consists of a supplier who uses a single vehicle with a given capacity to deliver a single type of product to many customers. We are interested in population-based algorithms to solve our problem. A Memetic Algorithm (MA) is developed based on Genetic Algorithm (GA) and Variable Neighborhood Search methods (VNS). The proposed metaheuristics are tested on small and large sizes referenced benchmarks. The results of MA are compared with those of classical GA and with the optimal solutions from the literature. The comparison showed the efficiency of the MA use and its ability to generate high quality solutions within a reasonable time.
Implementation fidelity of a transition program for adolescents with congenital heart disease: the STEPSTONES project
Authors: Saarijärvi Markus , Wallin Lars , Moons Philip , Gyllensten Hanna , Bratt Ewa-Lena 
Published: September 2021

Abstract
Background
Although transition programs have been evaluated for adolescents with chronic conditions, these have rarely involved process evaluations investigating the implementation process. The aim of this study was to evaluate the extent to which a transition program for adolescents with congenital heart disease was delivered as intended. Research questions were 1) to what level of fidelity was the program delivered? and 2) what potential moderating factors affected the delivery of the program and overall fidelity?
Methods
A mixed methods design was used, where a process evaluation was embedded in the STEPSTONES randomized controlled trial in Sweden. The implementation fidelity framework by Carrol (2007) and Hasson (2010) was used to design, collect and analyze data. Quantitative data consisted of intervention records on adherence and were analyzed with descriptive statistics. Qualitative data on moderators affecting fidelity were collected through interviews, log-books and focus group interviews with healthcare professionals implementing the intervention and participatory observations of the implementation process. Data were analyzed with deductive content analysis. Triangulation was used to integrate quantitative and qualitative data within the fidelity framework.
Results
Six out of eight components of the transition program were delivered to an extent that adhered to the program theory or achieved a high level of fidelity. However, components involving peer support had a low attendance by the participating sample (32.2%), and the joint transfer meeting was challenging to implement, despite achieving high adherence. Moderators affecting the implementation process were the adolescent’s and healthcare professional’s engagement in the intervention, contextual factors and a lack of standard operating procedures for all components in the program.
Conclusion
Barriers and facilitators for a future implementation of transition programs have been illuminated in this study. The use of an implementation fidelity framework in the process evaluation proved successful in providing a comprehensive evaluation of factors affecting the implementation process. However, implementation fidelity must be considered in relation to adaptations to the local and personal prerequisites in order to create interventions that can achieve fit.
Formation, preservation and extinction of high-pressure minerals in meteorites: temperature effects in shock metamorphism and shock classification
Authors: Hu Jinping , Sharp Thomas 
Published: September 2021

Abstract
The goal of classifying shock metamorphic features in meteorites is to estimate the corresponding shock pressure conditions. However, the temperature variability of shock metamorphism is equally important and can result in a diverse and heterogeneous set of shock features in samples with a common overall shock pressure. In particular, high-pressure (HP) minerals, which were previously used as a solid indicator of high shock pressure in meteorites, require complex pressure-temperature-time (P-T-t) histories to form and survive. First, parts of the sample must be heated to the melting temperatures, at high pressure, to enable rapid formation of HP minerals before pressure release. Second, the HP minerals must be rapidly cooled to below a critical temperature, before the pressure returns to ambient conditions, to avoid retrograde transformation to their low-pressure polymorphs. These two constraints require the sample to contain large temperature heterogeneities, e.g. melt veins in a cooler groundmass, during shock. In this study, we calculated shock temperatures and possible P-T paths of chondritic and differentiated mafic rocks for various shock pressures. These P-T conditions and paths, combined with observations from shocked meteorites, are used to constrain shock conditions and P-T-t histories of HP-mineral bearing samples. The need for rapid thermal quench of HP phases requires a relatively low bulk-shock temperature and therefore moderate shock pressures below ~ 30 GPa, which matches the stabilities of these HP minerals. The low-temperature moderate-pressure host rock generally shows moderate shock-deformation features consistent with S4 and, less commonly, S5 shock stages. Shock pressures in excess of 50 GPa in meteorites result in melt breccias with high overall post-shock temperatures that anneal out HP-mineral signatures. The presence of ringwoodite, which is commonly considered an indicator of the S6 shock stage, is inconsistent with pressures in excess of 30 GPa and does not represent shock conditions different from S4 shock conditions. Indeed, ringwoodite and coexisting HP minerals should be considered as robust evidence for moderate shock pressures (S4) rather than extreme shock (S6) near whole-rock melting.
Politics of Scale: Decentralization and Centralization of Oil Exploitation Right in Northern Shaanxi, China
Authors: GAO Yanhui , YANG Qingqing 
Published: September 2021

Abstract
Background: The impact of oil exploitation on local economy is often subject to the national resource management system. Monopolistic vertical resource management often makes local struggle ineffective. However, there is a successful local oil economy in China. This paper focuses on the formation of a special oil economy and reallocation of resources, power, and capital in Northern Shaanxi, China. This is a typical case of competing interests across multiple scales. It presents a typical case of the reconfiguration of resources, power, and capital at multiple scales.Methods: We introduce the ‘politics of scale’ to analyze the decentralization & centralization of oil exploitation rights, and the game among the government, state-owned enterprises, private enterprises and residents.Results: There are three findings. First, driven by fiscal interests, governments as the actual owners of the state capital, were directly involved in the politics of scale. Second, the interest conflicts among local state-owned enterprises, local governments were concealed owing to the strict administrative hierarchy and authority of the power, and they became a unified whole of interests and won the battle for oil resources with the central state-owned enterprises. Third, governments’ behavior strategies were simple and crude in scaling-down, mainly by hierarchical control and administrative orders. Private capital's behaviors were more diversified in scaling-up, but were completely suppressed and eliminated by the government agencies.Conclusions: We argue that politics of scale is an effective framework to explain multi-scale regulation, and is also a strategy of power competition among all practice parties.
Separability Analysis of Back-Scattering Coefficient of NovaSAR-1 S-band SAR datasets for different Land Use Land Cover (LULC) classes
Authors: Bhardwaj Ashutosh , Saini Ojasvi , Chatterjee R. S. 
Published: September 2021

Abstract
NovaSAR-1 is a joint technology initiative of SSTL (Surrey Satellite Technology Ltd.), UK, and Airbus DS (former EADS Astrium Ltd, Stevenage, UK). The NovaSAR-1 mini-satellite was launched on 16 September 2018 and it is operating on the S-band frequency range, which is less common in Spaceborne Synthetic Aperture Radar (SAR) systems. Both higher and lower SAR frequency bands (L-band & X-band SAR) have their advantages as well as limitations in different kinds of applications. High frequency (X-band) SAR systems are useful for top surface information extraction such as the DSM generation. However, at the same time, more noise and lesser coherence issues are associated with high-frequency SAR systems. Low-frequency SAR (L-band) systems exhibit better ground penetration, high coherence, and low noise, but less precise scatterer level information. The S-band comes approximately in the middle of the X and L-band SAR frequency range and may be used as a trade-off between high and low-frequency SAR systems to have some advantages. In the presented study, the separability analysis of the radar backscattering coefficient of HH polarization (Stripmap and ScanSAR) of NovaSAR-1 S-band datasets corresponding to different land use and land covers (LULCs) has been done to analyze the potential of NovaSAR-1 S-band SAR data. The analysis was carried out for datasets acquired between 9th July 2019 to 15th July 2019 at 5 experimental sites in parts of six different Indian states (West Bengal, Maharashtra, Jharkhand, Odisha, Chhattisgarh, and Uttar Pradesh). The statistical analysis of σ० for five different sites of India for different LULCs, such as bare soil, forest, water, urban, cropland, and road features has been carried out. The range for minimum and maximum mean σ० values for urban, sub-urban, cropland, bare soil, barren land, forest, turbid water, road features, water with a smooth surface (calm water), and road features (airplane runway) were found to be -5.45 to 4.76, -11.14 to -5.21, -17.25 to -5.99, -18.15 to -13.44, -17.64 to -9.34, -17.17 to -14.34, -18.2 to -14.05, -27.29 to -23.76 and − 26.64 to -14.98 respectively. The range of σ० pixel values of calibrated datasets corresponding to different LULCs depicted that the data quality is good for the identification of various land covers. The separability analysis of the different land cover classes depicted that classes have good separability except for a few pairs of LULC. With the availability of fully polarimetric and InSAR data in the planned NISAR mission, the polarimetric scattering behaviour with phase information for InSAR will further be utilized.
Data-Analytics-Based Factory Operation Strategies For Die-Casting Quality Enhancement
Authors: Kim Jun , Lee Ju Yeon 
Published: September 2021

Abstract
This paper proposes data-analytics-based factory operation strategies for the quality enhancement of die-casting. We first define the four main problems of die casting that result in lower quality: [P1] gaps between the input and output casting parameter values, [P2] occurrence of preheat shots, [P3] lateness of defect distinction, and [P4] worker-experience-based casting parameter tuning. To address these four problems, we derived seven tasks that should be conducted during factory operation: [T1] implementation of exploratory data analysis (EDA) for investigating the trends and correlations between data, [T2] deduction of the optimal casting parameter output values for the production of fair-quality products, [T3] deduction of the upper and lower control limits for casting parameter input–output gap management, [T4] development of a preheat shot diagnosis algorithm, [T5] development of a defect prediction algorithm, [T6] development of a defect cause diagnosis algorithm, and [T7] development of a casting parameter tuning algorithm. The details of the proposed data-analytics-based factory operation strategies with regard to the casting parameter input and output data, data preprocessing, data analytics method used, and implementation are presented and discussed. Finally, a case study of a die-casting factory in South Korea that has adopted the proposed strategies is introduced.
Noggin Combined With Dental Pulp Stem Cells Repair Muscle Injury Through Smad/Pax7 Signaling Pathway
Authors: Zhang Meng-Han , Yu Li-Ming , Zhang Wei-Hua , Deng Jia-Jia , Sun Bing-Jing , Chen Mei-Hua , Huang Wei , He Hua , Han Xin-Xin , Liu Yue-Hua 
Published: September 2021

Abstract
Background: A proper stem cell source is key to muscle injury repair. Dental pulp stem cells (DPSCs) are an available source for the treatment of muscle injury due to their high reproductive and differential activities. However, the application of DPSCs in muscle regeneration is incompletely understood. Noggin, a secreted BMP antagonist promoted by Wnt-1, is required for embryonic myogenesis. Our research is to study whether Noggin can promote myogenic differentiation of DPSCs, and then to investigate the repair effect of Noggin combined with DPSCs in muscle injury.Methods: DPSCs were treated with Noggin to induce myogenic differentiation in vitro. The levels of myogenic markers (MyoD, Desmin, MRF4 and MyHC), and satellite cell markers (Pax3, Pax7, Six1 and Eya2) were detected during this process. Next, we blocked the effect of Noggin by adding BMP, and Samd phosphorylation level was tested. Then, we implanted Noggin-pretreated DPSC combined Matrigel into the mouse tibialis anterior muscle with volumetric muscle loss (VML). After 30-day recovery, morphometric analysis of the tibialis anterior muscle was performed.Results: Noggin effectively increased myotube formation in DPSCs. We also found Noggin accelerated the skeletal myogenic differentiation of DPSCs and promote Pax7+ satellite-like cell generation. These satellite-like cells had the capacity to generate myofibers and could self-renew. Pax7 and Pax3 levels were repressed when blocked the effect of Noggin by adding BMP, and Noggin eliminated the level of BMP/Smad phosphorylation. This suggested that Noggin facilitated the skeletal myogenic differentiation of DPSCs via Smad/Pax7 pathway. Morphometric analysis of muscle cross-sections revealed that DPSCs therapy could increase repair size and decrease scar tissue in tibialis anterior muscle of VML. Moreover, Noggin-treated DPSCs can benefit to Pax7+ satellite cell pool and promote muscle regeneration. Conclusions: This work reveals that Noggin can promote the generation of satellite-like cells for the myogenic process in DPSCs through Smad/Pax7 signaling pathway, and these satellite-like cells bioconstructs might possess a relatively fast capacity to regenerate for muscle injury.
Rho Kinase Expression in Giant Cell Arteritis Validating pERM Intensity Score as a Method of Increasing Sensitivity of Temporal Artery Biopsy
Authors: Lally Lindsay , Narula Navneet , Goodfellow Nicola , Luqmani Raashid , Pisapia David , Spiera Robert 
Published: September 2021

Abstract
Background: Aberrant rho-kinase (ROCK) activity is implicated in pathogenesis of several vascular and immunologic disorders. We previously demonstrated evidence of increased ROCK activity in histopathologically negative temporal artery biopsies (TAB) of subjects with clinical Giant Cell Arteritis (GCA) compared to those without GCA. This study aimed to examine ROCK activity in a larger cohort of biopsy-negative GCA subjects and to validate the prior findings. Methods: Subjects were categorized into 2 groups based on clinical data 6-months after TAB: biopsy-negative GCA and controls without GCA. Paraffin-embedded TAB were stained for phosphorylated ezrin/radixin/moesin (pERM), a surrogate of ROCK activity, and scored by two pathologists blinded to clinical diagnosis using a previously derived scoring system. Three areas of the vessel (intima, adventitial and vasa vasorum) were scored for staining intensity on a scale of 0–2, with a maximum possible score of 6 for each TAB. As determined a priori, scores ³4 were considered a high pERM intensity score correlating with ROCK activity. TAB sections were also stained for unphosphorylated ERM, the inactive protein. Results: Thirty six subjects with biopsy-negative GCA and 43 controls were analyzed. There were no differences between groups in age, sex and corticosteroid dose. The mean pERM intensity score in non-GCA subjects was 3.9 ± 1.4 (compared to 5.0 ± 1.4 in those with GCA, p = 0.002). Using the predetermined cut-off of 4 to define high pERM intensity, subjects with GCA were significantly more likely to have a high pERM intensity score compared to non-GCA, OR 3.67, 95%CI :1.19,11.36; p= 0.019. The sensitivity of high pERM intensity score for diagnosis of GCA in histologically negative TAB was 86%, 95%CI: 70,95. Conclusions:. In this well characterized cohort, those with GCA and negative biopsies had significantly higher pERM intensity scores in TAB specimens compared to subjects without GCA. pERM staining has diagnostic significance in enhancing the sensitivity of TAB, and helps to define the clinically important group of biopsy-negative GCA. The ROCK pathway warrants further investigation in GCA and may be a potential therapeutic target