bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between socioeconomic status and self-reported, tested and diagnosed COVID-19 status during the first wave in the Northern Netherlands: a general population-based cohort from 49 474 adults
Authors: Zhu Yinjie , Duan Ming-Jie , Dijk Hermien H. , Freriks Roel D. , Dekker Louise H. , Mierau Jochen O. 
Published: March 2021

ObjectivesStudies in clinical settings showed a potential relationship between socioeconomic status (SES) and lifestyle factors with COVID-19, but it is still unknown whether this holds in the general population. In this study, we investigated the associations of SES with self-reported, tested and diagnosed COVID-19 status in the general population.Design, setting, participants and outcome measuresParticipants were 49 474 men and women (46±12 years) residing in the Northern Netherlands from the Lifelines cohort study. SES indicators and lifestyle factors (i.e., smoking status, physical activity, alcohol intake, diet quality, sleep time and TV watching time) were assessed by questionnaire from the Lifelines Biobank. Self-reported, tested and diagnosed COVID-19 status was obtained from the Lifelines COVID-19 questionnaire.ResultsThere were 4711 participants who self-reported having had a COVID-19 infection, 2883 participants tested for COVID-19, and 123 positive cases were diagnosed in this study population. After adjustment for age, sex, lifestyle factors, body mass index and ethnicity, we found that participants with low education or low income were less likely to self-report a COVID-19 infection (OR [95% CI]: low education 0.78 [0.71 to 0.86]; low income 0.86 [0.79 to 0.93]) and be tested for COVID-19 (OR [95% CI]: low education 0.58 [0.52 to 0.66]; low income 0.86 [0.78 to 0.95]) compared with high education or high income groups, respectively.ConclusionOur findings suggest that the low SES group was the most vulnerable population to self-reported and tested COVID-19 status in the general population.
Influence of continuous application of feedlot manure and legacy treatments on soil organic carbon, soil hydrophobicity, and soil water repellency
Authors: Miller J.J. , Owen M.L. , Hao X. , Yang X.M. , Drury C.F. , Chanasyk D.S. 
Published: March 2021

Continuous or discontinued manure applications to agricultural soils may impact soil organic carbon (SOC) and water balances because of manure carbon inputs and the potential for manure-induced soil hydrophobicity (SH) and soil water repellency (SWR). A laboratory study was conducted using a long-term (44 yr) field experiment on a clay loam soil to determine the effect of application rate of feedlot manure under dryland (0, 30, 60, and 120 Mg·ha−1 wet weight) and irrigation (0, 60, 120, and 180 Mg·ha−1) on SOC, SH, and SWR. In addition, we compared the effect of 44 yr of continuous annual manure applications (C44) to legacy treatments which had discontinued applications for 14 (D14) or 30 yr (D30). Laboratory measurements were conducted on air-dried and sieved (<2 mm) soil to determine SOC, SH using Fourier transform infrared spectroscopy, and SWR using the repellency index (RI) method. Mean RI values for all treatments ranged from 2.20 to 13.0, indicating subcritical (RI > 1.95) SWR. Manure application rate had a significant (P ≤ 0.05) and positive effect on SOC and SH, and both followed an exponential model. In contrast, RI had a negative response to the application rate under dryland and had no response under irrigation. Overall, positive responses of SOC and SH to application rate supported our hypothesis, but it was not supported for RI. The hypothesis of greater SOC, SH, and RI for continuous versus discontinued treatments was also supported for SOC and SH but not for RI.
Description of Shapiro steps on the potential energy surface of a Frenkel–Kontorova model Part I: The chain in a variable box
Authors: Quapp W. , Bofill J. M. 
Published: March 2021

AbstractWe explain the vibrations of a Frenkel–Kontorova (FK) model under Shapiro steps by the action of an external alternating force. We demonstrate Shapiro steps for a case with soft ‘springs’ between an 8-particles FK chain. Shapiro steps start with a single jump over the highest $$\hbox {SP}_4$$

SP
4

in the global valley through the PES. They finish with doubled, and again doubled oscillations. We study in this part I a traditional FK model with periodic boundary conditions.
Semi-empirical determination of the nuclear quadrupole moment of $$^{109}$$Sn
Authors: Elantkowska M. , Ruczkowski J. , Wilman S. , Suski M. 
Published: March 2021

AbstractThe nuclear quadrupole moment (Q) of $$^{109}$$

109

Sn was determined by means of hyperfine structure (hfs) many-body parametrization method. The hyperfine structure splittings for isotopes $$^{117-131}$$

117
-
131

Sn recently measured by Yordanov et al. (Commun Phys 3:1, 2020) were used in multiconfiguration semi-empirical calculations. The contributions from the second-order perturbation theory to the magnetic dipole hyperfine structure, concerning electrostatically correlated hyperfine interactions, were taken into consideration for even and odd configurations simultaneously. Contributions from the second-order perturbation theory to the electric quadrupole hyperfine structure, concerning spin–orbit correlated hyperfine interactions, were included for the first time.
Defining the Role of “Relational Producer” in Arts-and-Health Collaborations in Hospitals: A Reflection on Catalysts and Partnerships
Authors: Ledgard Anna , Hall Susannah , Layton Sofie , Storor Mark , Petto Nicky , Wray Jo , Biglino Giovanni 
Published: March 2021

Abstract
As the profile of the arts-and-health sector grows and interdisciplinary projects with public outcomes become more common, it is useful to explore roles and ways of working at the interface between different disciplines. The authors analyze the complex role of producer, likely to become increasingly relevant in this landscape. While incorporating aspects of existing roles (e.g. hospital arts manager, cultural venue participatory producer, independent creative producer, public engagement manager), the producer has a very specific raison d'être and could be defined as “relational producer.” This role is not well understood and yet central to this field of practice.
In the Circle of Sense and Nonsense: Through a Mathematical Model of Meaning
Authors: Burgin Mark , Seaman William 
Published: March 2021

Abstract
In this article, the authors explore the relations and interactions between sense and nonsense with a threefold goal: (1) elaborations of formal definitions of these concepts; (2) investigation of the processes of making sense from nonsense; (3) establishment of the mathematical foundations for a sense-nonsense theory. The authors thus extend the dyad sense-nonsense by introducing the concept no-sense, situated between sense and nonsense, and by extending the concept sense to the concept poly-sense. The authors construct a mathematical model of these concepts and related processes using structures such as logical calculus, logical variety and logical prevariety. This approach accords with Leonardo da Vinci’s opinion that “no human investigation can claim to be scientific if it doesn’t pass the test of mathematical proof.”
Emerging Native-Similar Neural Representations Underlie Non-Native Speech Category Learning Success
Authors: Feng Gangyi , Li Yu , Hsu Shen-Mou , Wong Patrick C. M. , Chou Tai-Li , Chandrasekaran Bharath 
Published: March 2021

Abstract
Learning non-native phonetic categories in adulthood is an exceptionally challenging task, characterized by large interindividual differences in learning speed and outcomes. The neurobiological mechanisms underlying the interindividual differences in the learning efficacy are not fully understood. Here we examine the extent to which training-induced neural representations of non-native Mandarin tone categories in English listeners (n = 53) are increasingly similar to those of the native listeners (n = 33) who acquired these categories early in infancy. We assess the extent to which the neural similarities in representational structure between non-native learners and native listeners are robust neuromarkers of interindividual differences in learning success. Using intersubject neural representational similarity (IS-NRS) analysis and predictive modeling on two functional magnetic resonance imaging datasets, we examined the neural representational mechanisms underlying speech category learning success. Learners’ neural representations that were significantly similar to the native listeners emerged in brain regions mediating speech perception following training; the extent of the emerging neural similarities with native listeners significantly predicted the learning speed and outcome in learners. The predictive power of IS-NRS outperformed models with other neural representational measures. Furthermore, neural representations underlying successful learning were multidimensional but cost-efficient in nature. The degree of the emergent native-similar neural representations was closely related to the robustness of neural sensitivity to feedback in the frontostriatal network. These findings provide important insights into the experience-dependent representational neuroplasticity underlying successful speech learning in adulthood and could be leveraged in designing individualized feedback-based training paradigms that maximize learning efficacy.
Using Ancillary Information from Radar-based Observations and Rain Gauges to Identify Error and Bias
Authors: Nelson Brian R. , Prat Olivier P. , Leeper Ronald 
Published: March 2021

AbstractAncillary information that exists within rain gauge and radar-based data sets provides opportunities to better identify error and bias between the two observing platforms as compared to error and bias statistics without ancillary information. These variables include precipitation type identification, air temperature, and radar quality. There are two NEXRAD based data sets used for reference; the National Centers for Environmental Prediction (NCEP) stage IV and the NOAA NEXRAD Reanalysis (NNR) gridded data sets. The NCEP stage IV data set is available at 4km hourly and includes radar-gauge bias adjusted precipitation estimates. The NNR data set is available at 1km at 5-minute and hourly time intervals and includes several different variables such as reflectivity, radar-only estimates, precipitation flag, radar quality indicator, and radar-gauge bias adjusted precipitation estimates. The NNR data product provides additional information to apply quality control such as identification of precipitation type, identification of storm type and Z-R relation. Other measures of quality control are a part of the NNR data product development. In addition, some of the variables are available at 5-minute scale. We compare the radar-based estimates with the rain gauge observations from the U.S. Climate Reference Network (USCRN). The USCRN network is available at the 5-minute scale and includes observations of air temperature, wind, and soil moisture among others. We present statistical comparisons of rain gauge observations with radar-based estimates by segmenting information based on precipitation type, air temperature, and radar quality indicator.
Intraoperative recurrent laryngeal nerve monitoring using endotracheal electromyography during parathyroidectomy for secondary hyperparathyroidism
Authors: Hiramitsu Takahisa , Tomosugi Toshihide , Okada Manabu , Futamura Kenta , Goto Norihiko , Narumi Shunji , Watarai Yoshihiko , Tominaga Yoshihiro , Ichimori Toshihiro 
Published: March 2021

Objective To investigate the factors associated with adherence of an enlarged parathyroid gland to the recurrent laryngeal nerve (RLN) and the effectiveness of intraoperative neural monitoring (IONM). Methods This single-center retrospective study involved samples from 197 consecutive patients (394 RLNs; 733 parathyroid glands) who underwent parathyroidectomy and transcervical thymectomy between September 2010 and December 2014. The presence of parathyroid gland adhesion to the RLN and the clinical characteristics of patients with and without nerve adhesion were recorded. All patients underwent intraoperative monitoring of the electromyographic responses of the vocal cords using the endotracheal NIM-Response 3.0 system. The patients’ postoperative clinical outcomes were recorded. Results Parathyroid gland adhesion to the RLN was significantly associated with maximum gland diameter (>15 mm), weight (>500 mg), and the presence of nodular hyperplasia. IONM demonstrated a sensitivity of 97.8%, specificity of 43.5%, and accuracy of 94.7% for detecting nerve damage. Parathyroid gland adhesion to 17 RLNs occurred in 3 cases (17.6%) of vocal cord paralysis, whereas the 377 glands without nerve adhesion resulted in vocal cord paralysis in 20 cases (5.3%). Conclusion Our findings demonstrated the effectiveness of IONM using endotracheal electromyography in patients who underwent parathyroidectomy for secondary hyperparathyroidism.
Establishment of a typing model for diffuse large B-cell lymphoma based on B-cell receptor repertoire sequencing
Authors: Jiang Wenhua , Wang Hailong , Zhou Shiyong , Zhu Guoqing , Gao Mingyou , Zhao Kuo , Zhang Limeng , Xie Xiaojing , Zhao Ning , Tian Caijuan , Zhang Zhenzhen , Yan Fang , Pan Yi , Liu Pengfei 
Published: March 2021

Abstract
Background
The purpose of this study was to construct a new typing model for diffuse large B-cell lymphoma (DLBCL) patients based on the B-cell receptor (BCR) and explore its potential molecular mechanism.

Methods
BCR repertoire sequencing and whole-exome sequencing were performed on formalin-fixed paraffin-embedded samples from 12 DLBCL patients. Subsequently, a typing model was built with cluster analysis, and prognostic indicators between the two groups were compared to verify the typing model. Then, mutation and bioinformatics analyses were conducted to investigate the potential biomarkers of prognostic differences between the two groups.

Results
Based on BCR sequencing data, we divided patients into two clusters (cluster 1 and cluster 2); this classification differed from the traditional typing method (GCB and non-GCB), in which cluster 1 included some non-GCB patients. The progression-free survival (PFS), overall survival (OS), metastasis and Shannon diversity index of IGH V-J and survival after chemotherapy were significantly different (P < 0.05) between the two clusters, but no statistical significance was found between the GCB and non-GCB groups. The mutation status of 248 genes was significantly different between cluster 1 and cluster 2. Among them, FTSJ3, MAGED2, and ODF3L2 were the specific mutated genes in all patients in cluster 2, and these genes could be considered critical to the different prognoses of the two clusters of DLBCL patients.

Conclusion
We constructed a new typing model of DLBCL based on BCR repertoire sequencing that can better predict the survival time after chemotherapy. FTSJ3, MAGED2, and ODF3L2 may represent key genes for the difference in prognosis between the two clusters.
Pathways into and out of homelessness among people with severe mental illness in rural Ethiopia: a qualitative study
Authors: Smartt Caroline , Ketema Kaleab , Frissa Souci , Tekola Bethlehem , Birhane Rahel , Eshetu Tigist , Selamu Medhin , Prince Martin , Fekadu Abebaw , Hanlon Charlotte 
Published: March 2021

Abstract
Background
Little is known about the pathways followed into and out of homelessness among people with experience of severe mental illness (SMI) living in rural, low-income country settings. Understanding these pathways is essential for the development of effective interventions to address homelessness and promote recovery. The aim of this study was to explore pathways into and out of homelessness in people with SMI in rural Ethiopia.

Methods
In-depth interviews were conducted with 15 people with SMI who had experienced homelessness and 11 caregivers. Study participants were identified through their participation in the PRIME project, which implemented a multi-component district level plan to improve access to mental health care in primary care in Sodo district, Ethiopia. People enrolled in PRIME who were diagnosed with SMI (schizophrenia, schizoaffective disorder or bipolar disorder) and who had reported experiencing homelessness at recruitment formed the sampling frame for this qualitative study. We used OpenCode 4.0 and Microsoft Excel for data management. Thematic analysis was conducted using an inductive approach.

Results
Study participants reported different patterns of homelessness, with some having experienced chronic and others an intermittent course. Periods of homelessness occurred when family resources were overwhelmed or not meeting the needs of the person with SMI. The most important pathways into homelessness were reported to result from family conflict and the worsening of mental ill health, interplaying with substance use in many cases. Participants also mentioned escape and/or wanting a change in environment, financial problems, and discrimination from the community as contributing to them leaving the home. Pathways out of homelessness included contact with (mental and physical) health care as a catalyst to the mobilization of other supports, family and community intervention, and self-initiated return.

Conclusions
Homelessness in people with SMI in this rural setting reflected complex health and social needs that were not matched by adequate care and support. Our study findings indicate that interventions to prevent and tackle homelessness in this and similar settings ought to focus on increasing family support, and ensuring access to acceptable and suitable housing, mental health care and social support.
Pre-operative ankle-brachial index for cardiovascular risk assessment in simultaneous pancreas–kidney transplant recipients: a simple and elegant strategy!
Authors: Hau Hans-Michael , Jahn Nora , Brunotte Max , Wagner Tristan , Rademacher Sebastian , Branzan Daniela , Sucher Elisabeth , Seehofer Daniel , Sucher Robert 
Published: March 2021

AbstractBackgroundPatients with insulin-dependent diabetes mellitus type 1 (IDDM1) and end-stage kidney disease (ESKD) undergoing simultaneous pancreas kidney transplantation (SPKT) are a population with diffuse atherosclerosis and elevated risk of cardio- and cerebrovascular morbidity and mortality. We aimed to investigate the feasibility of preoperative screening for peripheral arterial disease (PAD), specifically ankle-brachial index (ABI) testing, to predict peri- and postoperative outcomes in SPKT recipients.MethodsMedical data (2000–2016) from all patients with IDDM and ESKD undergoing SPKT at our transplant center were retrospectively analyzed. The correlation between PAD (defined by an abnormal ABI before SPKT and graft failure and mortality rates as primary end points, and the occurrence of acute myocardial infarction, cerebrovascular and peripheral vascular complications as secondary end points were investigated after adjustment for known cardiovascular risk factors.ResultsAmong 101 SPKT recipients in our transplant population who underwent structured physiological arterial studies, 17 patients (17%) were diagnosed with PAD before transplantation. PAD, as defined by a low ABI index, was an independent and significant predictor of death (HR, 2.99 (95% CI 1.00–8.87), p = 0.049) and pancreas graft failure (HR, 4.3 (95% CI 1.24–14.91), p = 0.022). No significant differences were observed for kidney graft failure (HR 1.85 (95% CI 0.76–4.50), p = 0.178). In terms of the secondary outcomes, patients with PAD were more likely to have myocardial infarction, stroke, limb ischemia, gangrene or amputation (HR, 2.90 (95% CI 1.19–7.04), p = 0.019).ConclusionsPre-transplant screening for PAD and cardiovascular risk factors with non-invasive ABI testing may help to reduce perioperative complications in high-risk patients. Future research on long-term outcomes might provide more in depth insights in optimal treatment strategies for PAD among SPKT recipients.
Towards implementing exercise into the prostate cancer care pathway: development of a theory and evidence-based intervention to train community-based exercise professionals to support change in patient exercise behaviour (The STAMINA trial)
Authors: Reale Sophie , Turner Rebecca R. , Sutton Eileen , Taylor Stephanie J. C. , Bourke Liam , Morrissey Dylan , Brown Janet , Rosario Derek J. , Steed Liz 
Published: March 2021

Abstract
Background
The National Institute for Health and Care Excellence (NICE) recommend that men on androgen deprivation therapy (ADT) for prostate cancer should receive supervised exercise to manage the side-effects of treatment. However, these recommendations are rarely implemented into practice. Community-based exercise professionals (CBEPs) represent an important target group to deliver the recommendations nationally, yet their standard training does not address the core competencies required to work with clinical populations, highlighting a need for further professional training. This paper describes the development of a training package to support CBEPs to deliver NICE recommendations.

Methods
Development of the intervention was guided by the Medical Research Council guidance for complex interventions and the Behaviour Change Wheel. In step one, target behaviours, together with their barriers and facilitators were identified from a literature review and focus groups with CBEPs (n = 22) and men on androgen deprivation therapy (n = 26). Focus group outputs were mapped onto the Theoretical Domains Framework (TDF) to identify theoretical constructs for change. In step two, behaviour change techniques and their mode of delivery were selected based on psychological theories and evidence to inform intervention content. In step three, the intervention was refined following delivery and subsequent feedback from intervention recipients and stakeholders.

Results
Six modifiable CBEPs target behaviours were identified to support the delivery of the NICE recommendations. Nine domains of the TDF were identified as key determinants of change, including: improving knowledge and skills and changing beliefs about consequences. To target the domains, we included 20 BCTs across 8 training modules and took a blended learning approach to accommodate different learning styles and preferences. Following test delivery to 11 CBEPs and feedback from 28 stakeholders, the training package was refined.

Conclusion
Established intervention development approaches provided a structured and transparent guide to intervention development. A training package for CBEPs was developed and should increase trust amongst patients and health care professionals when implementing exercise into prostate cancer care. Furthermore, if proven effective, the development and approach taken may provide a blueprint for replication in other clinical populations where exercise has proven efficacy but is insufficiently implemented.