bluuebunny/crossref_metadata_2025_split huggingface dataset:
Probiotics administration as a prevention for postoperative infectious complications in colorectal cancer patients: A literature review
Authors: Dalimarta Angela , Lestari Wiji 
Published: August 2021

Background Colorectal cancer is the third leading cause of death from cancer in adults in the United States, with increasing prevalence in other countries. Radical resection is the gold standard of treatment in most cases of colorectal cancer, with a high rate of postoperative complications. Perioperative probiotics can improve the immune response and the postoperative intestinal microbiota environment. Although several studies have shown the benefits of probiotics in preventing postoperative complications of infection, the administration of perioperative probiotics in colorectal cancer patients is still controversial.
Objective. The purpose of this critical appraisal is to know the effectiveness of administering probiotics to prevent infectious complications in colorectal cancer patients.
Methods. Literature research using Pubmed, Cochrane, and EBSCOhost was carried out and 2 articles were obtained in the form of meta-analysis using STATA v11 and Revman v5.2 that was critically examined using the FAITH method. A comprehensive search for all studies was done to find all relevant studies using both MeSH terms and text words. The article should describe the assessment of quality and criteria used in method section, also provide information on the quality of individual studies in result section to minimize bias. The result section should state whether heterogeneity exists and mention possible reasons.
Results. Based on 2 meta-analyses that have been critically examined, which each consisting of 13 and 7 studies, giving probiotics can reduce the overall infection rate after colorectal cancer surgery. One meta-analysis showed an odds ratio (OR) of 0.51 (95% CI: 0.38 – 0.68, p = 0.00). Probiotics, such as Lactobacillus acidophilus and Bifidobacterium longum can also reduce the incidence of surgical site infections (OR = 0.59, 95% CI 0.39 – 0.88, p = 0.01) and pneumonia (OR = 0.56, 95% CI 0.32 – 0.98, p = 0.04). Probiotics did not provide statistically significant benefits in preventing urinary tract infections, leakage of anastomosis, and duration of postoperative pyrexia compared to the control group. Seven articles analyzed in the second meta-analysis showed probiotics to be useful in preventing postoperative infections with OR 0.5388 (95% CI, 0.4058-0.7154, P <0.0001).
Conclusions. Combination of more than one strain of probiotics such as Lactobacillus and Bifidobacterium is promising for the prevention of infections in patients undergoing colorectal cancer surgery.
Sem eira, nem beira
Authors: Drumond Jô 
Published: August 2021

No interior de Minas, entende-se por “eira” um pequeno pedaço de chão, uma espécie de pátio, usado nas fazendas para limpar, secar e debulhar cereais, assim como para depositar canas-de-açúcar antes da moagem. Beira ou beiral é a parte do telhado que se sobressai em relação ao limite da construção. Quando se diz que determinada pessoa não tem “eira nem beira”, significa que se trata de um sem-terra ou então com moradia pobre, sem beiral. Enfim, trata-se de alguém sem relevância na sociedade, um joão-ninguém, expressão bem pejorativa.Em inglês se diz “John Doe”; em francês se diz “Monsieur Tout le Monde”. Há muitos deles mundo afora.
Quistes mesoteliales benignos con posible origen en las trompas de Falopio resecados por laparotomía
Authors: Bernal-Mesa Jorge Alberto , Del Valle-Saavedra Juan Jacobo , López-Uribe Federico 
Published: August 2021

Introducción. Los quistes mesoteliales benignos son una entidad poco frecuente, que ocurren especialmente en mujeres en edad reproductiva. Se deben a una proliferación anómala del mesotelio que puede ser originada en varias estructuras intraabdominales e inicialmente es asintomática.
Caso clínico. Se presenta el caso de una mujer de 20 años con un cuadro sugestivo de neoplasia maligna, en quien se confirmó el diagnóstico de quiste mesotelial originado en la trompa de Falopio derecha. Se realizó tratamiento quirúrgico exitoso.
Discusión. A pesar de la estrecha relación de esta entidad con el útero y los ovarios, no se encuentran reportes de quistes mesoteliales originados a partir de las trompas de Falopio. El tratamiento de los quistes mesoteliales es quirúrgico y en el caso de esta paciente se hizo con la finalidad de mejorar los síntomas y erradicar la enfermedad. Las decisiones fueron tomadas basadas en la opinión de expertos en oncología en una junta de tumores gastrointestinales.
Conclusiones. Los quistes mesoteliales son neoplasias de baja incidencia, pero se deben tener en cuenta como diagnóstico diferencial de los tumores abdominales. Se presenta el caso de una paciente tratada de forma quirúrgica con resultados exitosos y seguimiento a un año sin recurrencias
Fuentes de energía en apendicectomía laparoscópica en un programa académico de Cirugía general en Colombia
Authors: Ariza Aníbal , Gaitán Laura , Marroquín Lina , Márquez Alfonso , Diaz-Castrillón Carlos E. , Torregrosa Almonacid Lilian 
Published: August 2021

Introducción. La apendicectomía por laparoscopia se considera el patrón de oro en el tratamiento de la apendicitis aguda. Sin embargo, su disponibilidad es limitada en nuestro sistema de salud, principalmente por los costos asociados. El objetivo de este estudio fue evaluar la relación entre el uso de los diferentes tipos de energía y los métodos de ligadura de la base apendicular, con las complicaciones postoperatorias, al igual que describir los costos asociados.
Métodos. Estudio observacional analítico de una cohorte retrospectiva de pacientes mayores de 15 años a quienes se les realizó apendicectomía por laparoscopia, en un hospital universitario entre los años 2014 y 2018. Se utilizaron modelos de regresión logística y lineal para evaluar la relación entre métodos de ligadura del meso y base apendicular, desenlaces operatorios y costos.
Resultados. Se realizaron 2074 apendicectomías por laparoscopia, 58,2 % (n=1207) en mujeres, la edad mediana fue de 32 años. En el 71,5 % (n=1483) la apendicitis aguda no fue complicada. La energía monopolar para la ligadura del meso apendicular fue la utilizada más frecuentemente en 57,2 % (n=1187) y el Hem-o-lok® el más utilizado para la ligadura de la base apendicular en el 84,8 % (n=1759) de los pacientes. No se observaron diferencias estadísticamente significativas en la tasa de infección del sitio operatorio, reintervención o íleo. El uso de energía simple redujo los costos del procedimiento de manera significativa durante el período evaluado.
Discusión. El uso de energía monopolar demostró ser una técnica segura, reproducible y de menor costo en comparación con el uso de energía bipolar, independientemente de la fase de la apendicitis aguda. Lo anterior ha permitido que se realicen más apendicectomías por laparoscopia y que los médicos residentes de cirugía general puedan realizar procedimientos laparoscópicos de forma más temprana.
Improving Agricultural Value Chain Financing: A Case Study of Seng Cu Rice Chain in Lao Cai Province, Vietnam
Authors: Lam Bui Thi , Cuong Tran Huu , Hao Le Thi Thanh , Lebailly Philippe 
Published: August 2021

Nowadays, the value chain financing (AVCF) is considered as an effective agricultural financing approach in the world, however, its prevalence is still limited in developing countries, like Viet Nam. This paper analyses the financial gap between the demands and the actual credit obtained of the Seng Cu (SC) rice chain participants in Lao Cai. Cross-sectional data were collected from 160 face-to-face interviews with SC rice producers and from in-depth interviews with 31 other stakeholders involved in the chain (demand-side) and the representatives of district-branch banks (supply-side) in 2016 - 2017. Overall, almost chain actors had high financial demands, especially upland rice producers and the leading chain actor (TPC). However, they faced many credit constraints related to the strict risk-avoidance strategy and the collateral requirement of banks. Even the SC rice chain confirmed its high potential and many supportive linkages among them developed, the decision-making of banks on credit disbursements still depends on the individual capability of each chain actors, not the entire chain. Thus, the recommendations for policymakers, producers, and agribusiness are suggested to enhance the financial sources going in the chain and the effectiveness of chain actors in the locality.
A Case of Irritant Contact Dermatitis Mimicking as Localized Bullous Pemphigoid.
Authors: Ramesh A. , Kannan Rajkumar , Daniel Samuel Jeyaraj , Bhuvana M. 
Published: August 2021

Introduction: 19 years old adult male a college going scholar presented to the Derm OPD, with complaints of multiple clear fluid filled lesions over left forearm around the hemodialysis fistula site. Patient gave history of applying thrombophob ointment over fistula site, which led to development of tense blisters filled with clear fluid that mimics localized bullous pemphigoid, where in appropriate and adequate investigations proved it to be a case of Irritant Contact Dermatitis. Thrombophob ointment which contains benzyl nicotinate and heparin applied over the hemodialysis fistula site leads to bullous lesions of Irritant Contact Dermatitis (ICD)which mimics as localized bullous pemphigoid over fistula site.
Keywords: Hemodialysis fistula site,Irritant Contact Dermatitis, localized Bullous Pemphigoid.
РОЗВИТОК НАУКОВИХ ПОЛОЖЕННЯ СПРАВЕДЛИВЕ ЦІНОУТВОРЕННЯ В РЕСПУБЛІЦІ БІЛОРУСЬ
Authors: Макрак Світлана Василівна , Тетёркина Алла Михайлівна , Кохнович Ірина Миколаївна 
Published: August 2021

Insufficient efficiency of agriculture, its place and role in the system of the national economy predetermine the need to develop scientific provisions for the fair prices formation within the framework of relations between participants in the agri-food market. Purpose of article. Determine the fair price concept specifics for agricultural products, substantiate the functions and factors of its formation, identify the shortcomings of the current pricing policy in the agricultural sector of Belarus, formulate directions for improving the mechanism of state regulation of the industry development. The object of research is the mechanism of pricing for agricultural products in the Republic of Belarus. Methods used in research. The theoretical and methodological basis for the study was the domestic and foreign scientists works on pricing and the formation of the food cost. During the research, the following methods were used: monographic, abstract-logical, normative, synthesis and system analysis, etc. The hypothesis of the study. Achieving fair prices for rural products requires improving the practice of determining them. Presentation of the main material. The article presents the author's position in relation to the development of scientific and methodological approaches to fair pricing of agricultural products, which are based on the analysis of the agri-food products multi-link value chain. Originality and practical value. The scientific novelty of the research lies in the substantiation of theoretical approaches, principles and directions for the formation of fair prices for agricultural products, taking into account the specifics of the industry and the emerging intersectoral relations. Conclusions. Achieving a fair price is possible only through the implementation of the principles, laws and regularities of "justice" within the framework of the formation of effective relationships between business entities and the observance of national interests.
The Path of Promoting the Innovation of Teachers' Teaching Idea in School-based Teaching Research
Authors: Meng Yanan 
Published: August 2021

In the basic teaching reform, school-based teaching research belongs to a very important topic, so how can we integrate the new curriculum reform idea with the teachers' teaching idea reform and set up new teaching requirements and objectives? This is the most typical problem confronted by the majority of teachers in the actual teaching at this stage. In order to solve the problem effectively, it is necessary to carry out diversified teaching activities with "school-based teaching research" as the starting point, so as to set up a new teaching mechanism with rich connotation and various forms and realize the overall improvement of teaching quality. In this paper, the author conduct initial discussion on the characteristics and significance of school-based teaching research, and then think about the ways to promote teachers' teaching idea innovation in school-based teaching research, hoping to comprehensively improve the teaching level of China.
Learning How to Tailor Programmatic Offerings to Support Low-income, First-generation, and Racially Minoritized Student Success
Authors: Kezar Adrianna , Perez Rosemary J. , Kitchen Joseph A. , Hallett Ronald E. 
Published: August 2021

This study focused on the process of how the staff at the Thompson Scholars Learning Community (TSLC), a comprehensive college transition program, tailored the programmatic offerings to meet the needs of low-income, first generation and racialized minority students. Because college students are complex individuals, each of whom faces a unique set of challenges and opportunities, it is reasonable to hypothesize that tailoring support services to the multiple needs of each student may make them more effective. The research identifies a four-part iterative and cyclical process to tailor the programmatic offerings for students – beginning with the individual student and then using information about individual needs to scale to broader group level tailoring. This broadening or scaling process is a new contribution to the literature that has not previously been identified. The tailored approach we identified works at both individual and group levels, which makes it viable as an intervention for large numbers of students. The effort to attend to and learn about individual students ensures that the intervention still meets the needs of individuals, but the testing of these interventions more broadly allows for understanding how these approaches will work for diverse group level tailoring.
PIJAT BAYI MEMPENGARUHI BERAT BADAN BAYI DAN POLA TIDUR BAYI USIA 2-6 BULAN
Authors: Dinengsih Sri , Yustiana Refina Eka 
Published: August 2021

BABY MASSAGE INFLUENCES A BABY'S WEIGHTAND SLEEP PATTERNS FOR 2-6 MONTHS AGEBackground babies are very sensitive and delicate creatures, have needs that must be met, including physical, biological and emotional needs. Optimal growth and development of babies often experience disturbances or obstacles, one of which is weight gain and baby sleep patterns. Purpose of this study was to determine the effect of baby massage on weight gain and sleep patterns for babies aged 2-6 months in BPM Bidan E Kurnia Garut Regency in 2020. Methods is a pre-experimental design, with a pre-experimental research design with Intact-Group. Comparison. The samples of this study were 48 babies, 24 babies as the experimental group and 24 babies as the control group. Data collection used observation sheets. Data analysis used the T test. Results showed that the baby's weight in the control group was 6137.5 grams, while in the experimental group the baby's weight was 6729.2 grams. The baby's sleep pattern in the control group was 12.7 hours, while in the experimental group the sleep pattern was 14.6 hours. Conclusion there is an effect of infant massage on weight gain and sleep patterns in infants. Suggestion:Improving health education, counseling and demonstrations about infant massage to mothers Keywords: Massage baby, body weight, sleep patterns ABSTRAK Latar Belakang bayi merupakan makhluk yang sangat peka dan halus, memiliki kebutuhan yang harus dipenuhi meliputi kebutuhan fisik, biologis serta emosi. Pertumbuhan dan perkembangan bayi yang optimal sering sekali mengalami gangguan atau hambatan salah satunya adalah kenaikan berat badan dan pola tidur bayi.Tujuan penelitian ini untuk mengetahui pengaruh pijat bayi terhadap peningkatan berat badan dan pola tidur bayi usia 2-6 bulan di BPM Bidan E Kurnia Kabupaten Garut Tahun 2020.Metode penelitian Pre-experimental design, dengan desain penelitian pre-eksperimen dengan pretest dan post test desain. Sampel penelitian ini adalah 48 bayi, 24 bayi sebagai kelompok eksperimen dan 24 bayi sebagai kelompok kontrol. Pengumpulan data menggunakn lembar observasi.Analisis data menggunakan uji T independent.Hasil penelitian menunjukkan bahwa berat badan bayi pada kelompok kontrol adalah 6137,5 gram, sedangkan pada kelompok eksperimen berat badan bayi adalah 6729,2 gram. pola tidur bayi pada kelompok kontrol adalah 12,7 jam, sedangkan pada kelompok eksperimen pola tidurnya adalah 14,6 jam.Kesimpulan ada pengaruh pijat bayi terhadap peningkatan berat badan dan pola tidur pada bayi .Saran meningkatkan pendidikan kesehatan, penyuluhan dan demonstrasi tentang pijat bayi kepada ibu Kata Kunci : Pijat bayi, berat badan, pola tidur
O engajamento discente durante a pandemia por Covid-19 frente ao ensino remoto e ao uso do GoogleClassroom
Authors: Santos Júnior Sérgio Rômulo Alves dos , Almeida Júnior Railson Alves Correia de , Silva Syntia Meneses , Oliveira Ronaldo Simão de , Andrade Juliana Nascimento 
Published: August 2021

A crise sanitária provocada pelo Covid-19 impulsionou as aulas a distância através do ensino remoto e o uso de plataformas como o GoogleClassroom desenvolvido com foco na integração entre professores e alunos. O presente artigo teve como objetivo avaliar o engajamento discente durante a pandemia por Covid-19 frente ao ensino remoto e ao uso do GoogleClassroom. Tratou-se de um estudo de natureza básica, por meio de revisão bibliográfica, de caráter descritivo e exploratório, cujos dados foram tratados de maneira qualitativa para compreender a participação dos alunos nas aulas síncronas utilizando a ferramenta GoogleClassroom como plataforma de acompanhamento dos conteúdos abordados em aulas virtuais durante a pandemia. A pesquisa foi realizada por meio da realização de buscas nos repositórios bases Periódicos CAPES e Google Scholar, utilizando os seguintes descritores: “engajamento”, “ensino remoto”, “pandemia por Covid-19” e “GoogleClassroom”. Após a seleção criteriosa, foram selecionados 15 artigos publicados em periódicos nacionais dos últimos 5 anos. A análise dos artigos demonstra que as ferramentas educacionais de interação online permitiram a realização de um trabalho inovador, focado na formação inicial e continuada de alunos, bem como na integração entre os participantes da turma. O uso de plataformas online e aulas virtuais favoreceram o planejamento de ações, proporcionando ganho de conhecimento individual e coletivo.
The Association of Trp64Arg Polymorphism in the Beta-Adrenergic Receptor With Insulin Resistance: Meta-Analysis
Authors: Wang Hai-Dan , Zhang Cai-Shun , Li Man-Wen , Lin Qian , Zhang Qing , Liu De-Feng , Ma Zheng-Ye , Dong Jing 
Published: August 2021

BackgroundInsulin resistance is a metabolic disorder that occurs in type 2 diabetes mellitus and obesity. Genetic factors such as β3-adrenoceptor polymorphism (Trp64Arg) may be involved in IR and insulin secretion. However, their association is controversial. Therefore, the current meta-analysis was conducted to clarify the relationship between the Trp64Arg and IR.MethodsThe literature search was performed in PubMed, Embase, and Web of Science using the keywords “Receptors, Adrenergic, beta-3, Receptors, Adrenergic, Insulin Resistance, Protein-Coupled Receptor Kinase 3” from 2005 to February 7, 2021. We used a random-effects model to calculate the pooled effect size. We conducted subgroup analysis and regression analysis to identify sources of heterogeneity; and Egger’s test and funnel plot were used to test publication bias. Finally, we conducted a sensitivity analysis.ResultsWe included eight papers with 1,586 subjects. There was a positive correlation between Trp64Arg mutation and insulin level (standardized mean difference = 0.20, 95% confidence intervals: 0.00 to 0.39, I2 = 57.6%, p = 0.016). However, there was no association between Trp64Arg and the homeostasis model (HOMA-IR) assessment. Egger’s tests showed no publication bias; the sensitivity analysis showed that our results were stable. Regression analysis revealed no source of heterogeneity.ConclusionTrp64Arg may be associated with IR. European ancestry, obesity, plasma insulin level, and test status may be potential factors affecting the relationship between Trp64Arg and IR.
Plasma Concentration of 12-Hydroxyeicosatetraenoic Acid, Single Nucleotide Polymorphisms of 12-Lipooxygenase Gene and Vaso-Occlusion in Sickle Cell Disease
Authors: Duru Augustine Nwakuche , Ocheni Sunday , Ibegbulam Obike , Okpala Iheanyi 
Published: August 2021

Background and Novel Aspect of this Work: In the light of previous findings that inflammation predisposes to intercellular adhesion and microvascular occlusion in sickle cell disease (SCD), this study investigated the relationship between the number of vaso-occlusive events in SCD, plasma levels of the pro-inflammatory molecules 12-Hydroxyeicosatetraenoic acid (12-HETE), TNF-α and IL-1β; and single nucleotide polymorphisms (SNPs) in the gene 12-Lipooxygenase (ALOX-12), which encodes the enzyme 12-Lipoxygenase that catalyzes the biosynthesis of 12-HETE.Objective: To evaluate the relationship between vaso-occlusion in SCD and plasma concentrations of 12-HETE, TNF-α, and IL-1β; and single nucleotide polymorphisms (SNPs) in ALOX-12 gene.Participants and Methods: In 50 HbSS patients, the numbers of vaso-occlusive crisis requiring hospital treatment in the previous 1 year and the vaso-occlusive complications of SCD developed to date (e.g stroke) were added to obtain the vaso-occlusive events (VOE) score. In the HbSS patients and 30 healthy sibling control persons, plasma concentrations of 12-HETE, TNF-α and IL-1β were measured by ELISA, the ALOX12 SNPs rs2073438 and rs1126667 detected by DNA sequencing, and the accrued data statistically analyzed.Results: Compared to SCD patients with VOE score 0–1, those with scores ≥3 had higher plasma levels of 12-HETE (p &lt; 0.0001) and TNF-α (p = 0.19), but not IL-1β (p = 0.27). VOE score showed strong direct correlation with plasma level of 12-HETE (r = 0.65, p &lt; 0.0001), but not with TNF-α nor IL-1β. Neither VOE score nor plasma concentration of 12-HETE showed any relationship with the ALOX12 SNPs rs2073438 and rs1126667.Conclusion: The strong direct correlation of VOE score with plasma concentration of 12-HETE suggests that the clinical relevance of this pro-inflammatory molecule in SCD-associated vaso-occlusion needs to be evaluated in further studies.