bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence of dengue NS1 antigenemia among healthy blood donors in a tertiary care hospital in Southern India
Authors: Remakanth Remi , Basavarajegowda Abhishekh , Dhodapkar Rahul 
Published: November 2021

INTRODUCTION:
Transmission of dengue by transfusion of blood products has been documented, although the frequency of these occurrences and the level of viremia required to cause clinical dengue are unknown. The primary objective was to assess the prevalence of dengue NS1 antigen among healthy blood donors at our blood center.

METHODOLOGY:
This was a cross-sectional study conducted in the Department of Transfusion Medicine, a tertiary care hospital in South-eastern India, from February 2019 to January 2020. A total of 968 donor samples were included in the study. Dengue NS1 antigen detection was done using enzyme-linked immunosorbent assay. Data regarding clinical, epidemiological, and demographic characteristics were collected from the donor questionnaire and records.

RESULTS:
In the study, the overall prevalence of Dengue NS1 antigen was 0.9%, with nine positive samples among the 968 samples tested. Eight of them were male, and 1 was a female donor. All of them were in the age group <32 years. Half of the positive donors were detected during December-January, the immediate post rainy season in this part of the country. Two-third of the positive donors were from rural areas.

CONCLUSION:
This study with a 0.9% throws light on the seroepidemiological prevalence of dengue among asymptomatic donors and gives an insight into whether dengue screening is required to be implemented in routine transfusion transmissible infection screening in blood transfusion services and shall assist in devising strategies to be adapted as to improve the blood safety.
A review of legal, regulatory, and policy aspects of blood transfusion services in India
Authors: Mammen Joy John , Asirvatham Edwin Sam , Sarman Charishma Jones , Ranjan Varsha , Charles Bimal 
Published: November 2021

Background:
Blood transfusion services (BTS) in India have progressed significantly during the last three decades. However, there is still inequity in the availability and access to blood due to various demand and supply-side issues. Appropriate laws, regulations, policies, and guidelines are critical to ensure universal access to blood.

Aims and Objectives:
This article aims to review the evolution and current status of legal, regulatory, and policy framework and analyses the issues, challenges, and opportunities for improvement of BTS in India.

Methods:
This article is based on an extensive review of currently available literature and government documents.

Results:
The review highlights the gaps and challenges in terms of licensing, safety and quality, voluntary blood donations, the organization of BTS, access to services, and regulatory bodies. The findings emphasize the need for a coordinated response by either the National Blood Transfusion Council or a newly established autonomous “National Blood Authority” consisting of technical, administrative, and legal experts which must be exclusively responsible for regulating the BTS. As adherence to quality management systems in blood banks is not a mandatory requirement, it recommends a legal measure to ensure mandatory quality assurance in blood banks and storage centers. Towards ensuring efficiency and universal access to blood, this article recommends evidence-based criteria for establishing new blood banks to avoid skewed distribution of blood banks, component separation facilities, and blood storage centers.

Conclusion:
The review emphasizes the need for periodic reviews and updates of the legal, regulatory and policy framework, considering the rapid developments and technical advancements with increasingly complex systems and processes in transfusion medicine.
Comparison of mobilization with movement and Mulligan knee taping on Patellofemoral pain syndrome
Authors: Mubarra Rehman  , Huma Riaz  
Published: November 2021

Objective: The objectives of study are to compare Mobilization with Movement (MWM) and Mulligan knee taping (MT) on anterior knee pain, hamstring flexibility and Physical performance of lower limb.
Methods: A randomized control trail was conducted from July to Dec 2019. Ethical approval from Riphah research ethical committee was taken. Total 34 participants of both genders, having Patellofemoral pain were recruited by purposive sampling technique. Randomly assignment into two groups; MWM and MT was done. Both groups were treated for 2 days per 2 consecutive weeks. Outcomes measures were Numeric pain rating scale(NPRS), Kujala pain rating scale, Active knee extension test(AKE) and Time up and go test(TUG). Assessment were taken at baseline, 2nd and 6th weeks after treatment. Data analysis was done through SPSS-21 version.
Results: Between group analysis has shown statistically significant improvement (p< 0.000) in NPRS and Kujala score in MWM group whereas hamstring flexibility is significant in (p< 0.000) MT group. Within group analysis has shown a statistically significant differences (p< 0.000) for all outcome variable in both groups.
Conclusion: It is concluded that Mulligan’s MWM is more effective in treatment of patellofemoral pain and associated knee functional performance.
Clinical Trial Number: This clinical trail is prospectively registered at www.ClinicalTrails.gov(NCT04173468)
Keywords: Anterior knee Pain. Patellofemoral pain Syndrome, Mobilizations with Movement, Mulligan knee taping, Kujala pain rating scale, Active knee extension test,
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The effect of kangaroo mother care applied to the healthy newborns in the early postpartum period on breastfeeding: a randomized controlled trial
Authors: Sevda Korkut Oksuz  , Sevil Inal  
Published: November 2021

Objective: This study aims to determine the effect of kangaroo mother care applied to the healthy newborns in the early postpartum period on breastfeeding.
Methods: Our research was conducted over the period June 1 - August 25, 2016 at the obstetrics and maternity units in Istanbul. A of 112 healthy newborns and their mothers (56 in the study group and 56 in the control group) were recruited into a randomized controlled experimental study. The newborns in the study group were administered kangaroo mother care for 3 hours after birth while the control group of newborns was cared for using the unit’s standard postpartum procedures. The time the newborns in the study and control groups first started to breastfeed, the number of breastfeeding within the first 24 hours, the duration of their breastfeeding and suckling skills were evaluated.
Results: It was found that newborns subjected to kangaroo mother care provided immediately after delivery started suckling at the breast sooner (P = .001), for a longer period (P = .001) and more frequently (P = .001) than the newborns provided with standard post-delivery care. While there was no difference between the groups in terms of initial suckling skills (P = .862), the newborns in the kangaroo mother care group were better at suckling in the 24th hour (P = .001).
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JENERATİF SANAT: NÖROPLASTİSİTE VE DERİN ÖĞRENME İLİŞKİSİNDE POST DİJİTAL DÖNÜŞÜMLER
Authors: UYSAL Serpil , GÜNEY Engin 
Published: November 2021

21. yüzyılda kültürel dinamiklerin birbirleriyle etkileşimi bireysel ve toplumsal dönüşümleri hızlandırmaktadır. Sanal ve gerçek ayrımının giderek ortadan kalktığı, organik ve organik olmayan arasındaki hibrit yaşam, insan beyninin ve doğadaki problem çözme becerilerinin modellendiği teknolojilerle kurgulanmaktadır. Düşünce, duygu ve davranış geliştirebilen insan beyni, özgünlüğü, yaratıcılığı, hayal gücü, her yeni öğrenmeyle kendini dönüştürebilme potansiyeli, iletişim ağı ve örüntü oluşturabilme becerisiyle benzersiz bir bağlantısallığa sahiptir. Zihin inşa edebilen şuurlu insan beyninin makinelerle entegrasyonu ve insansı teknolojilere atfedilen üstünlük algısı, post dijital bir kültür tasarlamaktadır.
Teknoloji ve ideoloji gibi kültürel dinamiklerin etkisinde biçimlenen yeni sanat ekolojileri jeneratif sanatın kapsamını ve üretim motivasyonlarını dönüştürmektedir. Dönemin bilimsel bilgisinin ve teknolojisinin kullanıldığı jeneratif sistemler, post dijital süreçte yapay zekâ ve derin öğrenme algoritmalarıyla tasarlanmaktadır. Çalışmada, bir donanım olarak insan beyninin ve derin öğrenme algoritmalarının benzerlikleri ve ayrıştıkları hususlara temas edilerek insan ve insan olmayan arasında kurgulanan hibrit yaşam ve post dijital zeminde biçimlendirilen algılar sorgulanmaktadır.
ANÁLISE TOXICOLÓGICA NA ÁREA FORENSE: A UTILIZAÇÃO DA QUÍMICA NA DETECÇÃO DAS DROGAS DE ABUSO
Authors: Mori Lucas Barboza de , Cesar Francisco Ignácio Giocondo 
Published: November 2021

As drogas de abuso estão significativamente presentes na sociedade e veem acarretando grandes problemas de saúde pública, sociais e econômicos. Esse artigo tem como objetivo compreender a toxicologia[1] concernente às substâncias conhecidas como drogas de abuso, além de apresentar técnicas normalmente utilizadas por peritos criminais (peritos forenses) na elucidação de crimes, identificando a substância utilizada que levou o indivíduo ao ato violento. O artigo foi desenvolvido a partir de uma pesquisa bibliográfica exploratória, em bases de dados de referência científica, com o objetivo de buscar maior conhecimento sobre o assunto pesquisado, tais como: tipos de drogas de abuso, seus efeitos no corpo humano, dados estáticos relacionando-as com a criminalidade (quando encontrados) e as principais técnicas de identificação dessas drogas utilizadas na área forense. Como resultado sugere-se maior conhecimento sobre a toxicologia forense, assim como dos procedimentos para identificação das drogas de abuso pelos peritos forenses. Pode-se concluir que essas substâncias são extremamente prejudiciais aos indivíduos que as consomem com frequência, para as pessoas ao seu redor, e para a sociedade em geral. Por isso, o trabalho dos químicos forenses, de identificar e combater os crimes relacionados a substâncias psicoativas torna-se tão importante.
Employer Branding: O que as melhores empresas têm para atrair seus funcionários
Authors: Nogas Érika Mirian , Souza Fernanda Moreti de 
Published: November 2021

Este artigo analisa a relação entre a marca do empregador – ou employer branding – e o uso de ferramentas de gestão por competências por meio da análise de conteúdo de dados secundários sobre as melhores empresas para se trabalhar do estado do Paraná, do período de 2014 a 2020. A análise abrangeu as quatro melhores empresas de grande porte do Paraná. Os resultados mostraram que há uma relação entre o uso de gestão por competências e uma marca do empregador forte, pois as empresas analisadas utilizam ferramentas de gestão, avaliação, desenvolvimento e reconhecimento para atrair e reter funcionários, sendo este o principal objetivo da marca do empregador. ABSTRACT This paper analyzes the relation between the Employer Branding and the use of competency management tools through the content analysis of secondary data regarding the best companies to work in the state of Paraná from 2014 to 2020. The analysis covered the four best Paraná large companies. The results showed that there is a relation between the use of competency management and a strong Employer Brand, once the companies analyzed use management, evaluation, development and recognition tools to attract and retain employees, which is the main objective of the Employer Branding.
Changes in the extracellular matrix of the clitoris caused by aging: a stereological and comparative study
Authors: Pires Lucas , Babinski Monique , Fonseca Junior Albino , Manaia Jorge Henrique , Babinski Marcio 
Published: November 2021

IntroductionThe clitoris is partially responsible for sexual arousal. The integrity of the extracellular matrix is essential for clitoral erection. Sexual dysfunction is a phenomenon associated with age.Material and methodsThe clitoris of cadavers of 20- to 80-year-old women was excised and histologically processed. Stereological analysis was performed to quantify the volumetric density of collagen, elastic fibers, and smooth muscle.ResultsA significant increase in collagen and a decrease in smooth muscle and elastic fibers were observed in older women.ConclusionsIn short, these changes caused by aging could contribute to female sexual dysfunction concerning clitoral orgasm.
Liriodendrin alleviates sciatic endometriosis-associated pain in rats via suppressing inflammatory response and regulating the signaling pathway of Pl3K/Akt/mToR
Authors: Gong Jianfang , Xue Liangliang , Wei Mengling , Han Wenli , Jing Shen 
Published: November 2021

IntroductionLY294002 has been validated as a PI3K pan-inhibitor in the pathogenesis of airway inflammation, which attenuated IL-25-induced asthma-like AHR. Liriodendrin was proved to play essential roles in attenuating endometriosis-associated pain. This work aimed to gain a mechanical insight into the therapeutic efficiency of Liriodendrin administration on attenuating endometriosis-associated pain.Material and methodsVon Frey filament test and thermal hyperalgesia test were carried out to evaluate the acute and daily efficiency of drug administration. Western blot was used to analyze the expression of substance P, PI3K/AKT/mTOR, p-PI3K/p-AKT/p-mTOR, and CGRP. ELISA was performed to examine interleukin-1, interleukin-2, interleukin-6, TNF-α and PGE2 levels.ResultsAs a result, Liriodendrin significantly attenuated pain in endometriosis rats and restored the up-regulation of p-PI3K/p-AKT/p-mTOR in the endometriosis rats. The increased interleukin-1, interleukin-2, interleukin-6, TNF-α, and PGE2 levels were remarkably restored by Liriodendrin in endometriosis rats. Moreover, the activated expression of substance P in the ventral horn of the spinal cord of endometriosis rats was notably restored by Liriodendrin in addition to CGRP. Furthermore, Liriodendrin effectively restored the LPS induced up-regulation of p-PI3K/p-AKT/p-mTOR protein as well as the LPS activated IL-6, TNF-α, and IL-1β mRNA and protein expression in 12Z cells.ConclusionsWe found that compared with LY294200, Liriodendrin exerted a more evident therapeutic effect in the treatment of endometriosis-associated pain by suppressing the secretion of pro-inflammatory cytokines.
marco regulatorio del control político sobre el Órgano Ejecutivo (L)
Authors: López Alfaro Ruth Eleonora , Santos Guardado Ana Gabriela , Rivas Tenorio Hugo Álvaro 
Published: November 2021

El presente artículo aborda el aspecto normativo de algunas instituciones que ejercen control político sobre el órgano ejecutivo, a fin de caracterizar la letra “L”, que forma parte de los elementos de la rendición de cuentas horizontal. Para ello se describe el marco regulatorio de las prácticas de algunas instituciones que tienen facultades de control político sobre el Ejecutivo y se esbozan elementos del ordenamiento jurídico que precisan mejorar, a fin de tener una rendición de cuentas efectiva.
ECA Estudios Centroamericanos, Vol. 76, No. 765, 2021: 135-159.
Investigar las configuraciones subjetivas que los adolescentes construyen para enfrentar su realidad cuando uno o ambos padres migran irregularmente
Authors: Orellana Sibrián Rafael , Cavalletti Lucia , Ortiz Ponce Karla Josseline 
Published: November 2021

El presente trabajo representa un encuadre fructífero que señala aspectos claves para reflexionar sobre la configuración de las estrategias con que los adolescentes enfrentan los cambios en sus condiciones de vida cuando uno o ambos padres migran irregularmente. El objetivo general es conocer la configuración de factores psicosociales que, en sus ámbitos relacionales de vida y a partir de significados, visiones y valoraciones que los adolescentes construyen sobre su realidad, se constituyen en factores mediadores. Estos factores mediadores les permiten, bajo formas diversas, encontrar dinámicas sobre el control de su vida y de las condiciones que inciden en ella. De manera analítica y reflexiva, se realiza una revisión bibliográfica sobre el estado del arte del objeto de estudio, estructurado en tres ejes analíticos: a) situación socioemocional, b) reconfiguración familiar y c) situación socioeducativa que viven los niños, niñas y adolescentes cuando uno o ambos padres migrar irregularmente. Por medio de la revisión de la literatura, se encontró que la migración de uno o ambos padres produce diversos efectos tanto negativos como positivos a nivel personal, familiar y social en que viven estos niños, niñas y adolescentes. A través de la fundamentación teórica, se ha buscado enlazar los abordajes conceptuales con el propósito de esbozar una propuesta de investigación que tome en cuenta algunas dinámicas de importancia para entender el fenómeno; de igual manera, se presenta una propuesta de consideraciones metodológicas sugeridas. Estás incluyen estrategias mixtas en donde se privilegia la recolección de datos de corte cualitativo a través de entrevistas a profundidad y grupos focales.
ECA Estudios Centroamericanos, Vol. 76, No. 765, 2021: 207-239.
Simulation of Opening Angle of Archimedes Wind Turbine Design Based on the Fibonacci Series
Authors: Herraprastanti Eva Hertnacahyani , Agung Saputro Widianto 
Published: November 2021

The configuration of new type of turbine is the Archimedes wind turbine with a spiral structure whose design is inspired by logarithmic spirals. This type of wind turbine uses lift and drag to harness the kinetic energy of the wind. The eccentric design has aerodynamic characteristics that have been the focus of previous research. The design is made from the arrangement of the Fibonacci sequence (1x1, 2x2, 3x3, 5x5, 8x8) or commonly known as the golden ratio. This study aims to analyze the coefficient of lift (CL) and coefficient of drag (CD) with variations opening angle of 35°, 45°, 65°, air fluid, turbulent flow, Re 1200, pressure distribution 1 atm, wind speed 5, 5 and 15 m/s. The results is at wind speed of 5.5 m/s, an angle of 35°, the CL value is 1.07E+02, the CD value is 4.02E+04. At wind speed of 5.5 m/s, an angle of 45°, the CL value is 1.08E+04, the CD value is 1.77E+01. At wind speed of 5.5 m/s, an angle of 65°, the CL value is 1.84E+06, the CD value is 3.68E+04. At wind speed of 15 m/s, an angle of 35°, the CL value is 2.20E+03, the CD value is 9.76E+02. At wind speed of 15 m/s, an angle of 45°, the CL value is 5.51E+04, the CD value is 4.12E+02. At wind speed of 15 m/s, an angle of 65°, the CL value is 5.96E+01, the CD value is 1.33E+03. Based on this, it can be concluded that at wind speed of 5.5 m/s the higher the opening angle, the higher CL produced. At wind speed of 15 m/s the larger the opening angle the CD increases. This is because the higher the angle, the more it receives sweeps or catches the wind. While the unstable value generated in this simulation is generally a weakness in the wind turbine design.
Preparation and Characterization of Chitosan-Gelatin-Glycerol Biocomposite for Primary Wound Dressing
Authors: Suryati Suryati , Meriatna Meriatna , Sulhatun Sulhatun , Lestari Dwi Ayu 
Published: November 2021

Rice straw is one of material containing cellulose to produce Carboxymethyl Cellulose (CMC). CMC is a non toxic polysaccharide that produces from cellulose that widely used in the pharmaceutical, food, textile, detergent, and cosmetic products industries. There are two stages usually use to produce CMC which are mercerization and esterification processes. Rice straw waste is one of the materials to produce CMC, it has a cellulose content of 37.7%, hemi-cellulose 21.99%, and lignin 16.62 %. BPS Aceh shown that the total rice harvested area was 310.01 hectares, with a total production of 1.71 million tons, and rice produced at 982.57 thousand ton. This study aims to reduce waste and environmental pollution caused by rice straw and collects information of rice straw as a basic material to produce of carboxymethyl cellulose and to increase the economic value of rice straw. The effects of various wieght parameters sodium monochloroacetate on chemical properties of CMC that produce from rice straw were investigated in this research. Rice straw was collected from a rice field in Nisam, North Aceh. The research conducted by synthesizing 5 grams rice straw for 5.5 hours using NaOH and Sodium Monochloroacetate solutions. With variations weight of sodium monochloroacetate are 5,6,7,8 and 9 grams. The characterization of CMC was carried out by Fourier Transform Infrared (FTIR), CMC yield, DS, Viscosity, water content, pH. The result shows that addition of sodium monochloroacetate was significant factors influence the chemical properties on CMC. The CMC that produced in this study achieved to National Indonesia Standard (SNI).
Effect of Cassia fistula Hydroalcoholic Extract on Testosterone Induced Benign Prostatic Hyperplasia in Wistar Rats
Authors: Kashimawo Adesegun J. , James Kemelayefa O. , Nnamani Nnabuike D. 
Published: November 2021

Background and Purpose: Men of age 40 years and above are at risk of non-cancerous enlargement of the prostate gland also known as benign prostatic hyperplasia (BPH). Adverse drug reactions and treatment relapse limit the effectiveness of orthodox pharmacotherapies. This study evaluated the effect of Cassia fistula hydroalcoholic extract on BPH.
Methods: BPH was induced in Wistar rats by subcutaneous injection of 10 mg/kg/day of testosterone propionate (TP) for 7 days. The rats were randomly allotted to five groups: corn oil only; finasteride (FS) 5 mg/kg/day; and C. fistula extract at doses of 100, 200, and 400 mg/kg/day. A sixth group in which BPH was not induced received only the vehicle. At the end of 28 consecutive days of treatment, prostate and testicular weights and indices were evaluated. The in vitro antioxidant capacity of the extract was evaluated using the DPPH free radical scavenging method.
Results: The extract showed a very strong free radical scavenging activity with IC50 value of 1.58 µg/mL (IC50 of gallic acid = 0.63 µg/mL) due to the presence of secondary metabolites. The results also showed significant (P?0.0001) reduction in the prostate weight, prostatic index, testes weight, and testes index of C. fistula extract-treated rats when compared with the untreated BPH group.
Conclusion: These results suggest that C. fistula extract possesses potentials as a remedy for the treatment of BPH.
Sintering behavior and microwave dielectric properties of CaTi1-x(Nb1/2Al1/2)xO3
Authors: Khan Akbar , Ali Asif , Khan Izaz 
Published: November 2021

CaTi1-x(Nb1/2Al1/2)xO3 with x=0.1-0.5 ceramics were processed through solid state sintering. X-rays diffraction (XRD) patterns of the compositions showed that the samples have orthorhombic crystal structure with symmetry (Pbnm). The symmetry was further confirmed using Raman spectroscopy. A total of 13 Raman modes were detected, which were in agreement with the XRD results. Microstructure analysis of the samples showed porosity in the samples, presumably due to the substitution of Al, having high melting point. As the concentration of Al and Nb increased, relative permittivity (er), quality factor (Q×fo) and temperature coefficient of resonance frequency decreased. Optimum microwave dielectric properties were achieved for the composition x=0.5 sintered at 1650 °C for 8 h i.e., er ~27.09, Q×fo ~17378 GHz and tf ~ -2.5 ppm/°C.