bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association Between the Reproductive Health of Young Women and Cardiovascular Disease in Later Life: Umbrella Review
Authors: Okoth K. , Chandan J.S. , Marshall T. , Thangaratinam S. , Thomas G.N. , Nirantharakumar K. , Adderley N.J. 
Published: August 2021

(BMJ. 2020;371:1–21)
One third of annual global deaths (17.9 million) can be attributed to cardiovascular disease (CVD). Risk factors for women include some outcomes related to pregnancy and fertility, however, these are often underrecognized. Hypertensive disorders of pregnancy, gestational diabetes mellitus, placental abruption, and low birth weight, and preterm births occur in up to one third of parous women in developed countries. Risk of CVD is also associated with early age at menarche/early menopause and use of hormonal contraceptive agents. This study aimed to conduct an umbrella review of systematic reviews to evaluate associations between female-specific risk factors (eg, adverse pregnancy outcomes and issues related to fertility) and CVD outcomes.
Prelabour Uterine Rupture: Characteristics and Outcomes
Authors: Al-Zirqi  , Vangena S. 
Published: August 2021

(BJOG. 2020;127:1637–1644)
Prelabor uterine rupture is very rare. Complete uterine rupture is more likely in scarred uteri compared with unscarred uteri and can lead to catastrophic outcomes. While trial of labor after cesarean delivery is endorsed by the American College of Obstetricians and Gynecologists for appropriate patients, the repeat cesarean rate is around 91%. It is not clear which outcomes are associated with preterm uterine rupture. This retrospective study looked at data from Norway between 1967 and 2008 to identify the characteristics, risk factors, outcomes, and incidence of complete and partial rupture before onset of labor.
Obstetric Admissions to Intensive Care Units in Australia and New Zealand: A Registry-based Cohort Study
Authors: Maiden M.J. , Finnis M.E. , Duke G.J. , Huning E.Y.S. , Crozier T.M.E. , Nguyen N. , Biradar V. , McArthur C. , Pilcherd D. 
Published: August 2021

(BJOG. 2020;127:1558–1567)
Critically ill, obstetric patients have unique characteristics and despite risk for complications, this patient population is often excluded from research. While there have been single-center and regional studies as well as national reports from Canada, France, The Netherlands and the UK, the epidemiology of obstetric patients admitted to the intensive care unit (ICU) in the southern hemisphere is lacking. The aim of this study was to examine the epidemiology of critically ill, obstetric patients in Australia and New Zealand.
The Use of Magnetic Resonance Imaging to Predict Placenta Previa With Placenta Accreta Spectrum
Authors: Ishibashi H. , Miyamoto M. , Shinmoto H. , Soga S. , Matsuura H. , Kakimoto S. , Iwahashi H. , Sakamoto T. , Hada T. , Suzuki R. , Takano M. 
Published: August 2021

(Acta Obstet Gynecol Scand. 2020;99:1657–1665)
Placenta previa with placenta accrete spectrum (PAS) affects an increasing number of pregnancies and is associated with risk for massive hemorrhage and maternal morbidity. Recently, studies have examined the use of magnetic resonance imaging (MRI) to predict placenta previa with PAS. Some studies have found high specificity and sensitivity using certain MRI findings to make this prediction, while others have found this tool less useful. The aim of this study was to examine the diagnostic accuracy of MRI findings to predict posterior and anterior placenta previa with PAS.
Accuracy of the Edinburgh Postnatal Depression Scale (EPDS) for Screening to Detect Major Depression Among Pregnant and Postpartum Women: Systematic Review and Meta-analysis of Individual Participant Data
Authors: Levis B. , Negeri Z. , Sun Y. , Benedetti A. , Thombs B.D. 
Published: August 2021

(BMJ. 2020;371:m4022)
Depression in pregnant and postpartum women is common and rates of detection and management could potentially improve with screening. Self-report depression symptom questionnaires such as the Edinburgh Postnatal Depression Scale (EPDS) could be used as part of a full assessment when depression is suspected. This study used individual participant data meta-analysis to assess the accuracy of EPDS screening and whether EPDS screening accuracy differs by timing of screen, patient age, and residence.
Antenatal Dexamethasone for Early Preterm Birth in Low-resource Countries
Authors: Oladapo O.T. , Vogel J.P. , Piaggio G. , Nguyen M.H. , Althabe F. , Gülmezoglu A.M. , Bahl R. , Rao S.P.N. , De Costa A. , Gupta S. , Baqui A.H. , Khanam R. , Shahidullah M. , Chowdhury S.B. , Ahmed S. , Begum N. , D Roy A. , Shahed M.A. , Jaben I.A. , Yasmin F. , Rahman M.M. , Ara A. , Khatoon S. , Ara G. , Akter S. , Akhter N. , Dey P.R. , Sabur M.A. , Azad M.T. , Choudhury S.F. , Matin M.A. , Goudar S.S. , Dhaded S.M. , Metgud M.C. , Pujar Y.V. , Somannavar M.S. , Vernekar S.S. , Herekar V.R. , Bidri S.R. , Mathapati S.S. , Patil P.G. , Patil M.M. , Gudadinni M.R. , Bijapure H.R. , Mallapur A.A. , Katageri G.M. , Chikkamath S.B. , Yelamali B.C. , Pol R.R. , Misra S.S. , Das L. , Nanda S. , Nayak R.B. , Singh B. , Qureshi Z. , Were F. , Osoti A. , Gwako G. , Laving A. , Kinuthia J. , Mohamed H. , Aliyan N. , Barassa A. , Kibaru E. , Mbuga M. , Thuranira L. , Githua N.J. , Lusweti B. , Ayede A.I. , Falade A.G. , Adesina O.A. , Agunloye A.M. , Iyiola O.O. , Sanni W. , Ejinkeonye I.K. , Idris H.A. , Okoli C.V. , Irinyenikan T.A. , Olubosede O.A. , Bello O. , Omololu O.M. , Olutekunbi O.A. , Akintan A.L. , Owa O.O. , Oluwafemi R.O. , Eniowo I.P. , Fabamwo A.O. , Disu E.A. , Agbara J.O. , Adejuyigbe E.A. , Kuti O. , Anyabolu H.C. , Awowole I.O. , Fehintola A.O. , Kuti B.P. , Isah A.D. , Olateju E.K. , Abiodun O. , Dedeke O.F. , Akinkunmi F.B. , Oyeneyin L. , Adesiyun O. , Raji H.O. , Ande A.B.A. , Okonkwo . , Ariff S. , Soofi S.B. , Sheikh L. , Zulfiqar S. , Omer S. , Sikandar R. , Sheikh S. , Giordano D. , Gamerro H. , Carroli G. , Carvalho J. , Neilson J. , Molyneux E. , Yunis K. , Mugerwa K. , Chellani H.K. 
Published: August 2021

(N Engl J Med. 2020;383:2514–2525)
Antenatal glucocorticoids are a common intervention in preventing adverse outcomes associated with preterm birth. The evidence supporting this intervention is based on trials in high-resource settings, however, and a 2015 trial in low-resource countries found scaling up this intervention caused an increase in neonatal death, stillbirth and suspected maternal infection. The World Health Organization (WHO) has issued guidelines restricting the use of antenatal glucocorticoids to certain situations. This study, the WHO ACTION-1 (Antenatal Corticosteroids for Improving Outcomes in Preterm Newborns) trial, aimed to determine the levels of safety and efficacy of dexamethasone in women at risk for early preterm birth in low-resource countries compared with placebo.
What Is New About Transfusions for Preterm Infants? An Update
Authors: Kirpalani H. , Whyte R.K. 
Published: August 2021

(Neonatology. 2019;115:406–410)
Practices for the transfusion for preterm infants vary widely between centers and there is a lack of consensus on the best approach. There is only a small amount of randomized controlled trial (RCT) evidence available, but 2 larger trials comparing high and low hemoglobin transfusion levels will report their findings soon. These trials use an outcome of neurodevelopmental impairment at 2 years and together report on 1744 infants. This review aims to describe the conclusions of the existing RCT literature, call attention to new observational data, and discuss the possibility of individualizing blood transfusions in infants.
Anesthetic Management of Women With Heart Failure During Pregnancy: A Retrospective Cohort Study
Authors: Jayasooriya G. , Silversides C. , Raghavan G. , Balki M. 
Published: August 2021

(Int J Obstet Anesth. 2020;44:40–50)
The increases in plasma volume, cardiac output, and heart rate caused by pregnancy may also lead to heart failure in women with underlying cardiac disease. Pregnancy may even reveal first-time symptoms of cardiac disease in tandem with hemodynamic stress, presenting with de novo cardiovascular conditions such as preeclampsia or peripartum cardiomyopathy. Since hypertensive disorders complicate up to 10% of pregnancies, and because known associations exist between heart failure in pregnancy and preeclampsia, this study aimed to examine management (anesthetic, medical, and obstetric) and etiologies of pregnant women with clinical heart failure presenting to a tertiary care center in Canada.
The Crossed-leg Position Increases the Dimensions Within the Acoustic Target Window for Neuraxial Needle Placement in Term Pregnancy: A Prospective Observational Study
Authors: Sharma M. , Qasem F. , Sebbag I. , Jones P.M. , Singh S.I. 
Published: August 2021

(Int J Obstet Anesth. 2020;44:106–111)
Anatomic changes associated with pregnancy may render conduct of neuraxial procedures in parturients more difficult. The standard position for a neuraxial block requires a patient to sit on a bed with the spine flexed and legs supported on a stool, but spinal flexion may be improved by instead sitting cross-legged on the bed. Given the lack of prospective studies on this topic, the aim of this study was ultrasonographic assessment of the paramedian target area’s size when a pregnant woman sits in the cross-legged position (CLP) for neuraxial needle placement compared with standard sitting position (SP). The authors hypothesized that a CLP would increase the measured lengths of the posterior longitudinal ligament (PLL) indicating an improved acoustic window between vertebrae.
Determining Competence in Performing Obstetric Combined Spinal-epidural Procedures in Junior Anesthesiology Residents: Results From a Cumulative Sum Analysis
Authors: Lew E. , Allen J.C. , Goy R.W.L. , Ithnin F. , Sng B.L. 
Published: August 2021

(Int J Obstet Anesth. 2020;44:33–39)
Epidural techniques can be challenging to master and require practice. The required number of cases to demonstrate competency in epidural procedures varies widely. Residents must complete 40 epidural or combined spinal-epidurals (CSEs) to show competency according to Accreditation Council for Graduate Medical Education International (ACGME-I) requirements. At the study center, CSE training consists of didactic teaching, 10 one-on-one supervised sessions using a model, and 10 supervised and coached CSEs, followed by 3 Direct Observation of Procedures assessments. This study used cumulative sum (CUSUM) analysis, a tool for defining failure rates, plotting learning curves and mapping levels of competence, to determine the minimum experience needed to demonstrate competency in obstetric CSE procedures among junior residents.
Management of Pain After Cesarean Delivery Without Intrathecal Morphine: Networking for the Best Answer
Authors: Barry G. , Uppal V. 
Published: August 2021

(Can J Anesth/J Can Anesth. 2020;67:1704–1709)
Acute pain after cesarean delivery (CD) is a predictor of important short-term and long-term outcomes including postpartum depression. Intrathecal opioids are often provided as post-CD analgesia following CD using neuraxial analgesia. However, when spinal anesthesia or intrathecal morphine are not good options, truncal blocks and local anesthetic wound infiltration (WI) are possible alternatives. Common truncal blocks used in this context include the transversus abdominis plane (TAP) block or quadratus lumborum block (QLB). A recent network meta-analysis (NMA) by Sultan et al compared single-injection TAP block, single-dose WI and continuous wound catheter (WC) in terms of 24-hour opioid consumption. TAP block and WC showed lower opioid consumption and pain scores that WI or inactive control. TAP block also had a longer time-to-first analgesic request than inactive controls.
Patient and Procedural Risk Factors for Increased Postoperative Pain After Cesarean Delivery Under Neuraxial Anesthesia: A Retrospective Study
Authors: Mehdiratta J.E. , Saab R. , Chen Z. , Li Y.J. , Habib A.S. 
Published: August 2021

(Int J Obstet Anesth. 2020;44:60–67)
Satisfactory postcesarean pain management is important for many reasons, including allowing early mobility to decrease thromboembolic risk, improved newborn care, and decreased risk for postpartum depression. There is still room for improvement in the management of postoperative pain in cesarean patients and a need to better understand individual variability. This study aimed to identify risk factors associated with increased postoperative pain following cesarean delivery (CD).
Effects of State Law Limiting Postoperative Opioid Prescription in Patients After Cesarean Delivery
Authors: Potnuru P.P. , Patel S.D. , Birnbach D.J. , Epstein R.H. , Dudaryk R. 
Published: August 2021

(Anesth Analg. 2021;132:752–760)
Opioids are routinely prescribed following cesarean delivery in the United States, though 1 in 300 of these patients experience new-onset persistent opioid use. As the duration of opioid prescriptions is the strongest indicator of persistent opioid use, the State of Florida passed a law restricting the duration of opioid prescriptions for acute pain to 3 days. Prescriptions may be extended to 7 days if the prescriber documents medical necessity. Studies have been conducted examining the effects of these laws on the general surgery population, there is a lack of studies specifically exploring the impact on cesarean delivery patients. This study aimed to examine the impact of this law, HB 21, on discharge opioid prescription practices in patients undergoing cesarean delivery.
The resurgence risk of COVID-19 in the presence of immunity waning and ADE effect: a mathematical modelling study
Authors: Zhou Weike , Tang Biao , Bai Yao , Shao Yiming , Xiao Yanni , Tang Sanyi 
Published: August 2021

AbstractSince the end of 2020, the mass vaccination has been actively promoted and seemed to be effective to bring the COVID-19 pandemic under control. However, the fact of immunity waning and the possible existence of antibody-dependent enhancement (ADE) make the situation uncertain. We developed a dynamic model of COVID-19 incorporating vaccination and immunity waning, which was calibrated by using the data of accumulative vaccine doses administered and the COVID-19 epidemic in 2020 in mainland China. We explored how long the current vaccination program can prevent China in a low risk of resurgence, and how ADE affects the long-term trajectory of COVID-19 epidemics. The prediction suggests that the vaccination coverage with at least one dose reach 95.87%, and with two-doses reach 77.92% on August 31, 2021. However, even with the mass vaccination, randomly introducing infected cases in the post-vaccination period can result in large outbreaks quickly in the presence of immunity waning, particularly for SARS-CoV-2 variants with higher transmission ability. The results showed that with the current vaccination program and a proportion of 50% population wearing masks, mainland China can be protected in a low risk of resurgence till 2023/01/18. However, ADE effect and higher transmission ability for variants would significantly shorten the protective period for more than 1 year. Furthermore, intermittent outbreaks can occur while the peak values of the subsequential outbreaks are decreasing, meaning that subsequential outbreaks boosted the immunity in the population level, which further indicating that catching-up vaccination program can help to mitigate the possible outbreaks, even avoid the outbreaks. The findings reveal that integrated effects of multiple factors, including immunity waning, ADE, relaxed interventions, and higher transmission ability of variants, make the control of COVID-19 much more difficult. We should get ready for a long struggle with COVID-19, and should not totally rely on COVID-19 vaccine.
Dicer-to-Argonaute switch controls biogenesis of oncogenic miRNA
Authors: Winchester L. , van Bijsterveldt L. , Dhawan A. , Wigfield S. , Triantafyllidis C. , Haider S. , McIntyre A. , Humphrey T.C. , Harris A.L. , Buffa F.M. 
Published: August 2021

AbstractmiRNAs are post-transcriptional regulators of gene expression, controlling biological processes from development to pathogenesis. We asked whether the reshaped functional miRNA landscape in cancers is driven by altered transcription of its precursors, or altered biogenesis and maturation of miRNAs. Integrated analysis of genomic and transcriptomic data in 9,111 samples across 10 cancer types and healthy tissues revealed a recurrent genomic switch from DICER-dependent to non-canonical Argonaute-mediated, DICER-independent, miRNA biogenesis. Experimental validation in AGO2-amplified clinical samples and cancer cell lines confirmed that canonical miRNAs can undergo maturation in a DICER-independent manner, and that elevated Argonaute levels promote selective maturation of the oncogenic miR-106b/25 cluster as shown by the altered ratio of mature miRNA to immature pri-miRNA levels. The preferential maturation of these oncogenic miRNAs, whose processing bypasses DICER1, promotes cancer progression and predicts poor prognosis. This highlights the evolution of non-canonical AGO2-dependent oncomiR processing as a novel driver pathway in cancer.
The role of institutional environment in building communication professionals' trust and satisfaction: a moderated multiple-mediation analysis
Authors: Meng Juan , Berger Bruce K. 
Published: August 2021

PurposeAs an important group of internal stakeholders, communication professionals carry the responsibilities to communicate with multiple groups of audience and foster trusted and satisfied relationships, both internally and externally. However, while busy with taking care of various stakeholders, the trust–satisfaction perception of communication professionals is underrated. Therefore, this paper aims to shift the investigation of the trust–satisfaction relationship from general employees to this unique group of communicators. By incorporating three key factors in an institutional environment (i.e. job engagement, leadership performance and organizational culture and support), the authors further investigate the moderated mediating effects of those factors on the trust–satisfaction relationship.Design/methodology/approachA national online survey of communication professionals working and living in the USA was designed to test the trust–satisfaction relationship. Surveyed communication professionals were asked to evaluate their own perceptions on various institutional factors. A conceptual moderated multiple-mediation structural model was proposed and tested to identify the impact of a complicated institutional environment on the perceived trust–satisfaction relationship.FindingsResults confirmed a strong positive impact of trust in organization on communication professionals' perceived job satisfaction. Results also confirmed the mediating effects of job engagement and communication leaders' performance on such a trust–satisfaction relationship. The authors' moderated mediation analysis indicated the important role of organizational culture in this complicated institutional environment and its indirect impact on the trust–satisfaction relationship.Originality/valueThe research explored several important factors within a complicated institutional environment and their potential impact on trust–satisfaction relationship. More significantly, the authors focused on one unique group of internal stakeholders, communication professionals, by analyzing how these institutional factors affect their very own perceptions. Even though communication professionals carry the responsibilities of acting as the communication and strategy facilitators on behalf of their organization, their perceptions on trust and satisfaction are equally important and deserve more attention. Results of our research promote the understanding of the complicated mechanisms within corporate communication for an enhanced trust–satisfaction relationship between communication professionals and their organization.
Intercultural sensitivity and its effects on ELT curricula – Teacher insights
Authors: Etri Walead 
Published: August 2021

PurposeThis qualitative research set out to understand what teachers’ assessments were of the context of teaching as it relates to the curriculum, and what they consider appropriate for an optimal teaching and learning experience in a university English language teaching (ELT) context.Design/methodology/approachQualitative data were deemed required to understand the effects and understanding teachers had of the ELT curriculum as it played out in their teaching context. Focus group interviews and observations were the main method for data generation.FindingsThe context has a bearing on the ongoing development of teachers’ intercultural sensitivity (IS) frames and how they address IS over time in their context of teaching as it pertains to curriculum.Originality/valueThis is an original research paper which gives insight to knowledge about the relationship between ELT, curriculum and culture.
Prospect theory: an analysis of corporate actions and priorities in pandemic crisis
Authors: Tapas Poornima , Pillai Deepa 
Published: August 2021

Purpose
The purpose of this study is to examine and interpret the findings from different sources on the corporate decisions during COVID-19.

Design/methodology/approach
The COVID-19 is a new phenomenon; grounded theory research approach is adopted to develop propositions on prospect theory and strategic decisions. The paper examines and interprets the findings from different sources on the corporate decisions during COVID-19.

Findings
Conventionally, it is believed that innovation brings risks, and individuals preferred certainty over uncertainty, even if the gains under uncertainty were twice as high. But, the results of the study indicate a divergent trend. Under threat perceptions of risks, companies explore significant opportunities and possibilities for organizational growth.

Practical implications
The study provides a framework to analyze the strategic decisions of corporate enterprises. The decisions replicate value function as concave in a gain situation and convex in a loss realm in times of pandemic crises.

Originality/value
This paper uses “actions taken” by enterprises offering various solutions in the testing times. The study is multidisciplinary in nature; it analyses the transformation strategic decisions in the context of economic and social dimensions for surviving the pandemic crises. The study provides a foundation for future research, as inferences are based on select examples.