bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of physical therapy on posture and quality of life in subject with parkinson\\\\\\\'s disease
Authors: Gandhi Nensi Vaibhav , Rabari Rachana , Rathve Kinjal , Patel Shreya 
Published: October 2021

It is a chronic progressive degenerative disorder of extra pyramidal system caused by loss of dopaminergic neurons in the substantia nigra and characterized by tremors, rigidity, bradykinesia, and disturbance of gait and posture.The neuropsychiatric symptoms of PD may include depression, psychosis, apathy, impulse control disorders that are linked with the poor quality of life due to the progression of disease. Despite, cognitive impairment in PD is of great significance in terms of therapeutic approaches in order to deal with motor deficits of disorder. Multiple studies have revealed that exercise has been proven to be effective for the maintenance of health and well-being in Parkinson’s. More importantly it is shown to play a significant role in addressing secondary prevention based on strength, flexibility, functional independence as well as gait and balance respectively.To evaluate the effect of physical therapy on posture and quality of life in subject with Parkinson’s diseaseSource of Data: Radha multispecielist Hospital, Shreeji Hospital, Parul Shevashram,Venus.Sampaling Method: Convenience,samplingSample Size: 30 subject were included (15 in) each groupsSelection f Sample: convenientStudy Design: experimentalStudy Duration: 30 min/day/7 weekPost intervention assessment will be done by body posture questionnaire and SF-36, for posture and quality of life assessment in 30 subjects meeting inclusion and exclusion criteria dividing in to two group by convenience.Group AGroup B(1)Patient with 50 to 75 years of age (2)Participants patient diagnosed with Parkinson’s diseases (3) Both gender are included (4) The participants were at stage 3 of Parkinson’s disease, according the Hoehn and Yahr scale. (1) The examined patients did not have other coexisting neurodegenerative. (2)Mentally challenged (3) Orthopedic deformity. (1) Short form health survey. (20) Body posture questionnaire.This study included 30 patient 18 male and 12 female giving a sex ratio. Mean age of participant was 62 year. There were 15 patients in control group and 15 patients in experimental group. All patients completed treatment and evaluated at baseline and at the end of study. Mean value of sf-36 was 50.59 and 52.59 for experimental and control group respectively. These means later increase to 74.90 and 59.00 respectively with p value 0.001. Mean value of body posture questionnaire was 47.27 and50.07 for experimental and control group respectively. These mean later increase to72.47 and 59 respectively with p value 0.001 Statistically significant change was present for posture and quality of life with p&#60;0.001 for both group.The obtained results revealed that the influence of applied program had a positive influence on posture and quality of life in people with Parkinson’s disease.When functional movement is applied on a regular basis, improvement of quality of life and everyday life activities can be noticed.
Limites en la Atención a Discapacitados Intelectuales y Psicosociales en la actividad notarial en Ecuador
Authors: LUCAS BAQUE STALIN JAVIER , Albert Márquez José Jesús 
Published: October 2021

La evolución en materia de derecho de discapacidad ha avanzado sustancialmente a nivel internacional como en legislaciones nacionales. El punto más álgido es la aprobación de la Convención Internacional sobre los Derechos de las Personas con Discapacidad en el 2006, cuyo principal aporte es el reconocimiento del derecho de ejercicio de la capacidad jurídica de las personas con discapacidad intelectual y psicosocial. En Ecuador, a pesar de haberse ratificado este instrumento internacional en el 2008, la legislación interna sigue siendo oscura, incompatible, contradictoria e inaplicable acarreando un conflicto teórico de naturaleza civil y sobre todo práctico en el ejercicio de la actividad notarial. Precisamente la dificultad que representa al notario ecuatoriano prestar la atención a este grupo de personas, no obstante, de la existencia de legislación internacional y nacional que propugna el derecho de obrar del discapacitado intelectual y psicosocial, constituye el objeto principal de este trabajo.
Para la realización de un adecuado análisis e interpretación de las normas jurídicas pertinente, utilizamos los métodos jurídicos: exegético y hermenéutico jurídico. El resultado es una visión global, actualizada y presentada desde la óptica del notario público. Su abordamiento tras 15 años desde la aprobación de la mencionada Convención internacional y su aún no adecuación de forma clara en la legislación ecuatoriana justifican la importancia de su estudio en materia de Derecho Social de los discapacitados y del Derecho Notarial ecuatoriano.
Potensi Bahan Alami dalam Menekan Produksi CH4 dan N2O dari Tanah Sawah
Authors: Susilawati Helena Lina , Wihardjaka Anicetus , Nurhasan Nurhasan , Setyanto Prihasto 
Published: October 2021

Low nitrogen efficiency is one of the sources of greenhouse gas (GHG) emissions from rice fields. Methane (CH4) and nitrous oxide (N2O) emissions could be controlled by nitrification inhibitors (NI). However, NI that has been commercialized is expensive. Therefore, some natural materials should be developed as NI that is low cost, easy to use, low N2O and CH4, and eco-friendly. The objective of this study was to observe the effect of natural NI on the production potential of CH4 and N2O from paddy soil. The experiment in the laboratory was arranged in a factorial design (2 × 7 × 3 replication). The first factor was soil types (inceptisols and vertisols), and the second factor was natural NI (control, Cocos nucifera, Camellia sinensis, Coffea robusta, Curcuma domestica, Ageratum conyzoides). The results showed that the average CH4 production from the natural NI in the inceptisols and vertisols ranged 0,014-1,710 mg CH4 g soil-1 and 0,002-0,337 mg CH4 g soil-1, respectively. Application of natural NI reduced 32-69% CH4 production compare to control. Redox potential affected CH4 production. The chemical compound of the natural NI affected CH4 production in the soil. The application of coffee waste, coconut husk, tea waste, and Ageratum conyzoides reduced 60,71; 54,61; 64,83 dan 64,16% of N2O production in Inceptisols compare to control, respectively. Application of natural NI could contribute to save the environment because it decreased GHG production in paddy soil.

Keywords: greenhouse gas, inceptisols, incubation experiment, natural nitrification inhibitors, vertisols
Aplikasi Dosis Vermikompos dan Urea Pada Tanaman Kedelai Varietas Anjasmoro di Tanah Berpasir
Authors: Pujiwati Hesti , Widodo Widodo , Prameswari Wuri , Salamah Umi , Dharmawangsa Leonardo , Susilo Edi , Husna Muhimmatul 
Published: October 2021

The low area for soybean plantation is still a major problem in meeting soybean needs. One of the efforts to increase national soybean production is by expanding the planting area by utilizing the sandy soil area that is still not used for soybean cultivation. This research was conducted from September-November 2020 in a greenhouse of the Agronomy Laboratory, Bengkulu University. This study aims to obtain the best dose of urea and vermicompost for the growth and yield of soybean in sandy soil. The research design used a completely randomized block design with two factors and 3 replications. The first factor was the dose of urea consisting of four levels, namely U0 = 0 kg ha-1, U1 = 50 kg ha-1, U2 = 100 kg ha-1, and U3 = 150 kg ha-1. The second factor was the dose of vermicompost, namely K0 = 0 ton ha-1, K1 = 5 tons ha-1, K2 = 10 ton ha-1, and K3 = 15 ton ha-1. The measured variables were the plant growth and the yield. Soil and vermicompost analyses were carried out before the study. The results showed that there was an interaction between the vermicompost and the urea dosages. The 100 kg ha-1 urea and the 10 ton ha-1 vermicompost treatment gave the highest plant height. The 150 kg ha-1 urea dan the 15 ton ha-1 vermicompost treatment formed the most number of branches. The highest soybean yield was given by 15 ton ha-1 vermicompost and 50 kg ha-1 urea to the total pod and the seed weight. Keywords: sandy soil, soybean, urea, vermicompost
Detecting Fake Users on Social Media with a Graph Database
Authors: Zhao Yichun , Weber Jens 
Published: October 2021

Social media has become a major part of people’s daily lives as it provides users with the convenience to connect with people, interact with friends, share personal content with others, and gather information. However, it also creates opportunities for fake users. Fake users on social media may be perceived as popular and influential if not detected. They might spread false information or fake news by making it look real, manipulating real users into making certain decisions. In computer science, a social network can be treated as a graph, which is a data structure consisting of nodes being the social media users, and edges being the connections between users. Graph data can be stored in a graph database for efficient data analysis. In this paper, we propose using a graph database to achieve an increased scalability to accommodate larger graphs. Centrality measures as features were extracted for the random forest classifier to successfully detect fake users with high precision, recall, and accuracy. We have achieved promising results especially when compared with previous studies.
Factors Causing the Development of the Endowment in Safavid Dynasty
Authors: Jamshidirad Mohammad Sadeq , Taher Yaghoubi Mohammad , Mohammad Reza Husseini Seyyed , Jamshidirad Hussein 
Published: October 2021

The tradition of the endowment is one of the activities having existed in all human societies from past to now. In Iran, this tradition was seen as a belief from ancient civilization. It is developed and flourished in Safavid dynasty so that, in Isfahan (Iran), the endowed estate is found everywhere. The endowment is so important that public, rich people and imperial family participated in this tradition and endowed their properties. This study has aimed to answer this question: what reasons and factors developed the endowment and what is the role of endowment in Safavid time? To do so, library and descriptive-analytic methods were used in this study.
Implementation of SPA Art.22 UN CRC on Children Displaced by Natural Disaster Victims in Lombok, West Nusa Tenggara, Indonesia
Authors: Lukman Lukman , Gani Arsyad Abd , Ismail Hijril , Asbah Asbah , Junaidin Junaidin , Sudarwo Raden , Edi Edi 
Published: October 2021

Role of ALIT in handling EARTHQUAKE LOMBOK, in general, during times of earthquakes, the situation that occurs in children must stay in displacement. By looking at the conditions in refugee camps that are dense, hot, the difficulty of water supply and the absence of sanitation facilities, especially waterways and MCK, the conditions of children are increasingly difficult. During the earthquake in Lombok, ALIT and its volunteer team assisted in four posts including: Paoki Rempel, Gangga sub-district, there were. In order to follow up on a number of previous programs, further forms of future activities need to be formulated which include: 1) Carry out monitoring related to social, economic and health developments in two the place of the main post located in the village of Paoki Rempel, Gangga District and Lading-lading Village, Tanjung Subdistrict periodically; 2) Exploring other potential of existing commodities to be reprocessed so as to increase their economic value in the villages of Paoki Rempel and Desa Lading-lading; 3) ALIT volunteers on duty in the field routinely provide assistance to two villages which will be prioritized, namely the villages of Paoki Rempel and Desa Lading-lading involving 8 remaining volunteers focused on three fields, education, health and development of the creative economy; 4) Building and facilitating the formation of small teams in order to encourage policies that have a perspective on the protection of children during disasters; 5) Disseminate the results of discussions of academic texts to the empowerment ministry women, social ministries and BNPB; 6) Maintain harmonious communication with stakeholders in the region North Lombok.
COVID-19 Pandemic and Indigenous Representation in Public Health Data
Authors: Huyser Kimberly R. , Horse Aggie J. Yellow , Kuhlemeier Alena A. , Huyser Michelle R. 
Published: October 2021

Public Health 3.0 calls for the inclusion of new partners and novel data to bring systemic change to the US public health landscape. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has illuminated significant data gaps influenced by ongoing colonial legacies of racism and erasure. American Indian and Alaska Native (AI/AN) populations and communities have been disproportionately affected by incomplete public health data and by the COVID-19 pandemic itself. Our findings indicate that only 26 US states were able to calculate COVID-19‒related death rates for AI/AN populations. Given that 37 states have Indian Health Service locations, we argue that public health researchers and practitioners should have a far larger data set of aggregated public health information on AI/AN populations. Despite enormous obstacles, local Tribal facilities have created effective community responses to COVID-19 testing, tracking, and vaccine administration. Their knowledge can lead the way to a healthier nation. Federal and state governments and health agencies must learn to responsibly support Tribal efforts, collect data from AI/AN persons in partnership with Indian Health Service and Tribal governments, and communicate effectively with Tribal authorities to ensure Indigenous data sovereignty. (Am J Public Health. 2021;111(S3): S208–S214. https://doi.org/10.2105/AJPH.2021.306415 )
Varlitinib induced differential Protein Expression analysis on oral carcinoma cell line: A therapeutic approach
Authors: Tanveer Fariha , Ilyas Amber , Syed Basir , Hashim Zehra , Ahmed Aftab , Zarina Shamshad 
Published: October 2021

Abstract
Receptor-ligand complex mediated signaling significantly contributesin cellular activities such as growth, proliferation, differentiation, and survival. However, augmented expression of signal transducing receptors and ligands is the most frequent molecular event and major hallmark of oral carcinogenesis. Among these receptors, Epidermal Growth Factor Receptor (EGFR) with intracellular tyrosine kinase activity is the most frequently overexpressed molecule by Squamous epithelial cells of oral cavity. Aberrated EGFR mediated signaling has laid the foundation of targeted therapy thus providing rationale for the conducted study. We have selected EGFR pathway as targeted intracellular signaling cascade inOral squamous cell carcinoma (OSCC). Deactivating EGFR by blocking the binding sites is likely to result in prevention of intracellular downstream signaling. In this context, Tyrosine Kinase Inhibitors (TKIs) have come into play. Quinazolines (aromatic heterocyclic compounds) and their derivatives have shown promising clinical outcomes. Present study focused to investigate anti-EGFR potential of quinazoline derivative, varlitinib-a pan-EGFR inhibitor on oral squamous epithelial cell lines. We performed proteomic analyses to identify differential expression pattern of proteins in SCC-25 cells in response to varlitinib treatment. Identified proteins include Binding Immunoglobulin Protein (BiP), Heat Shock Protein 7C (HSP7C), Protein Disulfide Isomerase 1 A (PDIA1), Vimentin (VIME), Keratin type I Cytoskeletal 14 (K1C14), and β-Actin (ACTB). Among these, five proteinswere found to be downregulated upon varlitinib treatment whereas only Keratin type I Cytoskeletal 14 was upregulated. Differential expression of proteins and possible role of varlitinib as potential antitumor drug in oral carcinoma is discussed.
Acclimation Response and Ability of Growth and Photosynthesis of Terrestrial Cyanobacterium Cylindrospermum sp. Strain FS 64 Under Combined Environmental Factors
Authors: Bahavar Nadia , Shokravi Shadman 
Published: October 2021

Abstract
This investigation tested the hypothesis that the native cyanobacteria can acclimatize and grow under the combination of environmental factors and/or how does their process change with the age of culture? Here, we tried to combine multiple factors to simulated what happens in natural ecosystems. We analyzed the physiological response of terrestrial cyanobacterium, Cylindrospermum sp. FS 64 under combination effect of different salinity (17, 80, and 160 mM) and alkaline pHs (9 and 11) at extremely limited carbon dioxide concentration (no aeration) up to 96h. Our evidence showed that growth, biomass, photosystem II, and phycobilisome activity significantly increased under 80 mM salinity and pH 11. In addition, this combined condition led to a significant increase in maximum light-saturated photosynthesis activity and photosynthetic efficiency. While phycobilisomes and photosystem activity decreased by increasing salinity (160 mM) which caused decreased growth rates after 96h. The single-cell study (CLMS microscopy) which illustrated the physiological state of the individual and active-cell confirmed the efficiency and effectiveness of both photosystems and phycobilisome under the combined effect of 80 mM salinity and pH 11.
Unraveling the Bacterial Assisted Degradation Pathway of Morpholine- a Xenobiotic Micropollutant: A Sustainability for Zero Pollution Environment
Authors: Kumar Rupak , Kapur Suman , Vulichi Srinivasa Rao 
Published: October 2021

Abstract
Biodegradation is the process by which chemicals both natural and xenobiotics are metabolized by microorganisms. Most naturally occurring chemical compounds are biodegradable while xenobiotic may be biodegradable, persistent or recalcitrant. Xenobiotic chemicals, because they are manmade and have developed recently, are present in the environment for comparatively shorter periods of time from its geological presence. This in turn means that the microbial communities present in these environments may not have evolved specific mechanisms for their degradation. Morpholine, a known xenobiotics micropollutant initially believes to be recalcitrant but later prove to be biodegradable by specific set of bacterium species most likely Mycobacterium and Pseudomonas sp in particular. However, the metabolic pathways involved in the successful biodegradation of morpholine stand challenging to establish because of its extreme water solubility and the lack of any chromophore group in morpholine which does not allow easy extraction process. Consequently, no tool for direct estimation of intermediates or metabolites of morpholine has been well reported and only indirect strategies have been developed like presence of microbial growth on intermediates, chemical/analytical assay for intermediate and ammonia measurements to elucidate the degradation pathway for zero pollution environment. In this present study degradation pathway has been ascertained by some selected bacterial isolate for their capacity to degrade morpholine. Based on the said analysis of culture filtrate, it has been revealed that the isolate namely Halobacillus utilizes glycolic route of the metabolic degradation pathway of morpholine and supports the fact that in presence of morpholine, one of two branches of morpholine biodegradation pathway namely ethanolamine and glycolate was was induced while the other branch was inhibited. Whatever the degradation pathway of morpholine exhibited by bacteria, ammonia is the end product of degradation which would be biochemically utilized by isolate.
Dirac-Source Diode with Sub-unity Ideality Factor
Authors: Myeong Gyuho , Shin Wongil , Kim Seungho , Lim Hongsik , Kim Boram , Jin Taehyeok , Sung Kyunghwan , Park Jihoon , Fuhrer Michael , Watanabe Kenji , Taniguchi Takashi , Liu Fei , Cho Sungjae 
Published: October 2021

Abstract
An increase in power consumption necessitates a low-power circuit technology to extend Moore’s law. Low-power transistors, such as tunnel field-effect transistors (TFETs)1-5, negative-capacitance field-effect transistors (NC-FETs)6, and Dirac-source field-effect transistors (DS-FETs)7-10, have been realised to break the thermionic limit of the subthreshold swing (SS). However, a low-power diode rectifier, which breaks the thermionic limit of an ideality factor (η) of 1 at room temperature, has not been proposed yet. In this study, we have realised a DS diode, which exhibits a steep-slope characteristic curve, by utilising the linear density of states (DOSs) of graphene7. For the developed DS diode, η < 1 for more than two decades of drain current with a minimum value of 0.8, and the rectifying ratio is large (> 105). The realisation of a DS diode paves the way for the development of low-power electronic circuits.
Single-Incision Port Robot-Assisted Surgery for Thymic Carcinoid Tumor Resection
Authors: SHIDEI HIROAKI , Mitsuboshi Shota , Yamamoto Tomoko , Kanzaki Masato 
Published: October 2021

Abstract
Background: Multiple endocrine neoplasia (MEN) is divided into MEN type 1 (MEN-1) and MEN type 2 (MEN-2). MEN-1 may be associated with thymic carcinoid tumors. We present a case of the surgical removal of a thymic carcinoid associated with MEN-1 via a single-incision port RATS.Case presentation: A 39-year-old male patient with multiple endocrine neoplasia type 1 (MEN-1) who had an anterior mediastinal mass was referred to our hospital. The patient had undergone total parathyroidectomy and auto-transplantation of a partial parathyroid for hyperparathyroidism 6 years ago. Chest computed tomography revealed an isolated anterior mediastinal mass on the thymic gland with a maximum diameter measuring 22 mm. Thymic carcinoid tumor is classified as MEN-1 and has a poor prognosis, so we decided to remove the tumor. Single-incision port RATS was performed, and thymic carcinoid was confirmed in pathology.Conclusions: This report demonstrates that thymic carcinoid tumor removal is feasible and easy to perform via single-incision port RATS.