bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Comparison of Hotel Guest Experience Before and During Pandemic: Evidence from Online Reviews
Authors: Chan Irene Cheng Chu , Ma Jing , Ye Huiyue , Law Rob 
Published: January 2021

AbstractThis paper compares the determinants of guest experience at luxury hotels in Mainland China before and during the pandemic—COVID-19. In particular, 740 Chinese reviews posted before the pandemic outbreak, and 1283 reviews posted during the pandemic were collected. Text analytics were applied to segment and count the frequency of words in these online reviews. The results show that the core dimensions of guest experiences at luxury hotels include services, room quality and settings, hotel facilities, dining, location, and environment. These core dimensions do not change regardless of the period before or during the pandemic. However, guests have higher expectations on hotel services such as late check-out and delivery service of takeaway during the pandemic. Online reviews amid-pandemic also contain words related to pandemic prevention and control measures, such as guest traffic and body temperature. Suggestions on operations and management are provided for hotel practitioners to improve their services during the critical period.
Examining Post COVID-19 Tourist Concerns Using Sentiment Analysis and Topic Modeling
Authors: Balasubramanian Sreejith , Kaitheri Supriya , Nanath Krishnadas , Sreejith Sony , Paris Cody Morris 
Published: January 2021

AbstractThe COVID-19 pandemic has had a destructive effect on the tourism sector, especially on tourists’ fears and risk perceptions, and is likely to have a lasting impact on their intention to travel. Governments and businesses worldwide looking to revive and revamp their tourism sector, therefore, must first develop a critical understanding of tourist concerns starting from the dreaming/planning phase to booking, travel, stay, and experiencing. This formed the motivation of this study, which empirically examines the tourist sentiments and concerns across the tourism supply chain. Natural Language Processing (NLP) using sentiment analysis and Latent Dirichlet Allocation (LDA) approach was applied to analyze the semi-structured survey data collected from 72 respondents. Practitioners and policymakers could use the study findings to enable various support mechanisms for restoring tourist confidence and help them adjust to the’new normal.’
How Artificial Intelligence Will Change the Future of Tourism Industry: The Practice in China
Authors: Tuo Yanzheng , Ning Lanyu , Zhu Aiyuan 
Published: January 2021

AbstractIn the future, artificial intelligence (AI) is likely to substantially change both the tourism industry and tourist behavior. At present, research on artificial intelligence and tourism is receiving widespread attention, but most of them focus on a certain subject or a specific aspect of the tourism industry. For example, artificial intelligence influences the behavior of tourists and tourism enterprises. The analysis of the impact of artificial intelligence on the tourism industry as a system is still insufficient. Therefore, this research proposes a multi-dimensional framework from an industry perspective based on the existing definition of artificial intelligence. The framework involves three aspects: the level of intelligence, task types, and whether artificial intelligence is embedded in robots. The authors use a large number of Chinese practice cases to investigate how AI affects the tourism industry, then put forward a research agenda to analyze how destination government, tourism enterprises and tourist experience will change in the future. Finally, they highlight important issues related to privacy, prejudice and ethics.
Co-creating Personalised Experiences in the Context of the Personalisation-Privacy Paradox
Authors: Volchek Katerina , Yu Joanne , Neuhofer Barbara , Egger Roman , Rainoldi Mattia 
Published: January 2021

AbstractThe personalisation-privacy paradox demonstrates a two-fold effect of tourists’ awareness about personalisation on their experience. Compulsory personal data agreements under the GDPR and similar legislation acts raise tourists’ concerns regarding privacy and security. The role of tourist awareness about the value of data-driven personalisation in their co-creation behaviour remains underexplored. This paper applies an exploratory experiment methodology to identify the effects of information about personalisation on tourists’ experience with travel information websites. It triangulates the data from eye-tracking and self-report techniques, to compare the co-creating behaviour of respondents who have or have not been informed about the value of personalisation. The study demonstrates the presence of a personalisation-privacy paradox. It further reveals that awareness about data-driven personalisation motivates tourists to reinforce value co-creation by ensuring the accuracy of information filtering. The study advances our understanding of tourist digital behaviour and provides insights for the design of personalised information services.
A Platform for Difficulty Assessment and Recommendation of Hiking Trails
Authors: Calbimonte Jean-Paul , Martin Simon , Calvaresi Davide , Cotting Alexandre 
Published: January 2021

AbstractIn recent years, the popularity of hiking has steadily increased across different segments of the population. Although there is considerable evidence of the benefits for hikers regarding physical and mental health, the inherent risks of these outdoor activities cannot be underestimated. Accident prevention and an increase of awareness about possible risks are necessary to minimize hiking and pedestrian tourism’s negative consequences. In most hiking information maps and interactive applications, there is usually not enough information about difficulty points or the granularity level required to provide tailored recommendations to hikers with physical or psychological limitations. In this paper, we present Syris, a geo-information system for hiking itineraries that incorporates Points-Of-Difficulty to assess the level of effort, technique, and risk of hiking trails. The system allows users to filter itineraries and obtain recommendations based on the assessment of difficulty following a well-established methodology. The system has been implemented, deployed and tested with real data in the region of Val d’Anniviers in Switzerland, and is openly available to enable further developments and refinement.
General Context of Smallholder Farmers’ Access to Seed of Improved Legume Varieties and Innovation Platform Perspectives
Authors: Akpo Essegbemon , Ojiewo Chris O. , Kapran Issoufou , Omoigui Lucky O. , Diama Agathe , Varshney Rajeev K. 
Published: January 2021

AbstractThe high percentage of farmers (80–90%), including the pro-poor in remote areas, who have no access to recently released and high-yielding varieties proves the failure of various seed delivery models implemented so far. The ideal model to grow a crop commodity business to reach farmers in developing countries with seed of improved legume crop varieties has been a hard topic for development organizations. Past studies have shown that the full and balanced integration of multiple stakeholders’ knowledge and contexts into the process of agricultural technology development increases the uptake and ownership among end users.
Impacts of Cowpea Innovation Platforms in Sustaining TL III Project Gains in Ghana
Authors: Yirzagla Julius , Atokple Ibrahim K. D. , Haruna Mohammed , Mohammed Abdul Razak , Adobaba Desmond , Haruna Bashiru , Karikari Benjamin 
Published: January 2021

AbstractOver the past decades, farm-level yields of cowpea have remained low (0.6–0.8 t/ha) compared to what is observed on research fields (1.8–2.5 t/ha). Lack of farmer access to quality seeds of improved varieties and inappropriate cultural practices are the major factors responsible for the low productivity of the crop. The use of Innovative Platforms (IPs) as a strategy to facilitate farmer access to quality seeds was, therefore, considered under the Tropical Legume (TL) III and USAID Cowpea Outscaling projects in Northern Ghana. The platform activities started in 2016 with a total membership of 100, which increased steadily to 820 by December 2018. The research team of the Council for Scientific and Industrial Research-Savannah Agricultural Research Institute (CSIR-SARI) trained platform members to produce certified seeds to be supplied to target communities, thereby enhancing smallholder farmers’ access to improved varieties. A total of 1848 members of the platform were trained in various farm operations. A revolving system was set up in which each farmer group was supplied with improved seed and after harvesting returned the equivalent of seed received to the platform. Having been trained to produce their own seed, members of the platform are self-reliant in acquiring improved seed and are actively engaged in various operations that sustain the gains of the two projects that have been phased out.
Groundnut Seed Production and Distribution Through Multi-Stakeholder Platforms in Southern Region of Tanzania
Authors: Lukurugu Gerald Alex , Mponda Omari Kalanje , Akpo Essegbemon , Monyo Emmanuel S. , Nzunda Joseph , Daudi Happy , Joseph Athanas , Mlimbila Hamphfrey George , Ndolelwa David , Mkandawile Charles 
Published: January 2021

AbstractSouthern Groundnut Platform (SGP) was established in 2016 to enhance seed access and adoption of improved groundnut varieties by farmers. The platform serves all districts in Lindi and Mtwara regions and Tunduru district in Ruvuma region. The platform has 53 members of which 22 are females and 31 are males. Since its establishment, there has been a marked increase in farm advisory services using government extension officers, community extension services and lead farmers. Groundnut seed production and distribution networks have increased to include more actors such as NGOs, seed companies, farmers groups and individual seed entrepreneurs. The increased seed access to farmers in the southern zone has contributed to 11% increase in area under cultivation resulting in 15% increase in groundnut production in Nanyumbu district between 2012 and 2018. New market linkages formed helped improve farm gate prices by 80% (from Tshs. 1000 to 1800). The platform also introduced 29 new labour saving technologies reducing women drudgery and increasing farmer improved varieties choice from 3 to 11 new varieties released between 2009 and 2018.
Kolokani Groundnut Innovation Platform Activities and Achievements Through TL III Project in Mali
Authors: Sako Dramane , Traoré Mamary , Doumbia Folocoum , Diallo Fodé , Fané Moussa , Kapran Issoufou 
Published: January 2021

AbstractGroundnut productions have been declining in Mali in spite of several new improved varieties being released, the key problem being inadequacy of the seed supply system. To solve this problem, Kolokani MSP was established in 2012 and reorganized with support from TL III in 2015 to include more stakeholders in the groundnut value chain—farmers particularly women, farmer associations, cooperative societies, seed producers, agro-dealers, grain traders, processors, research and extension. Four new varieties Fleur11, ICGV 86124, ICGV 86015, and ICGV 86024 were supplied to the platform for FPVS and among them two, Fleur 11 and ICGV 86124 were preferred for their high yields and large grain size under farmer conditions. Through training of trainers, the different members of the platform reached 1246 farmers among them 928 women with improved groundnut seed production, aflatoxin management, seed business plans, and small-scale mechanization. A total 47 FPVS, 50 Demonstrations, and three multi-locational variety trials were conducted annually from 2016 to 2018. Kolokani platform have played an important role in groundnut value chain by producing and marketing 85 tons groundnut certified seed of these varieties annually for farmers. This is expected to stop the national productivity decline while improving platform members’ livelihoods and nutrition status.
Enhancing Access to Quality Seed of Improved Groundnut Varieties Through Multi-Stakeholder Platforms in Northern Ghana
Authors: Puozaa Doris K. , Jinbaani Alhassan Nuhu , Adogoba Desmond S. , Busagri Douglas , Rasheed Masawudu Abdul , Issah Abdul Rashid , Oteng-Frimpong Richard 
Published: January 2021

AbstractOne of the main constraints to groundnut production has been the use of low yielding varieties, susceptible to biotic and abiotic stresses. Multi-stakeholder platforms (MSPs) have been used by agricultural research organizations to help make their research more relevant and to facilitate the adaptation and dissemination of findings. In the implementation of TLIII project in Ghana, eight MSPs were set up with the objective to improve groundnut productivity among actors through improved access to varieties and related technologies. Through trainings, demonstrations and field days, the platform members totalling 347 (55% being female) were exposed to two existing improved groundnut varieties and several candidate varieties which were yet to be released. The actors have become important sources of high-quality groundnut seed in their communities and beyond with the production of 5 tons of seed of the new varieties. The seed farms where improved varieties were planted and managed using good agronomic practices (GAPS) yielded up to 1.6 tons/ha, 70% higher than the use of their old varieties and practices on their personal farms which gave less than 0.5 tons/ha. This form of experiential learning was observed to be very useful in the willingness of platform members to uptake technology. As unintended benefits, through the use of funds raised by the associations, the sanitation and health of some members and their households were improved, and many engaged in non-farm businesses. Going forward, good conflict resolution skills and access to funds for supporting platform activities and members’ individual interests would be very important in the sustainability of these platforms.
Developing Sustainable Cowpea Seed Systems for Smallholder Farmers through Innovation Platforms in Nigeria: Experience of TL III Project
Authors: Iorlamen Teryima , Omoigui Lucky O. , Kamara Alpha Y. , Garba Umar , Iyorkaa Nater , Ademulegun Temitope , Solomon Reuben 
Published: January 2021

AbstractLimited access to and low use of quality seed of improved varieties rank among the topmost causes of persistently low cowpea yields in Nigeria. This paper presents experiences under the Tropical Legume III (TL III) project in facilitating the access of smallholder farmers to seeds of improved cowpea varieties through the establishment of innovation platforms (IPs) that were introduced in 2015 as part of the activities of the TL III project. There was rapid adoption and use of newly released varieties by farmers as a result of increased awareness of improved varieties through multi-media and user-friendly communication strategies and tools. During the four years of the project (2015–2018), a total of seven multi-stakeholder platforms (MSPs), which comprised six seed companies, 46 farmer groups, five public seed enterprises, two NGOs, and 718 individual seed entrepreneurs and other stakeholders, were established/strengthened to link actors in the cowpea value chain. Community-based seed producers were linked to seed companies while seed companies were linked to research institutions to access early generation seed (EGS). These activities led to the production of over 532 tons of basic seed and 8366 tons of certified/QDS seed of improved cowpea varieties that were entrenched in the seed system. Yield also increased almost twofold from 500 to 900 kg/ha on farmers’ field. Women and youth incomes increased as a result of seed entrepreneurship activities. The small packs approach was an efficient and cost-effective means of reaching more farmers with affordable quantities of seed and a wide range of preferred varieties.
Transcriptomics analysis of hepatotoxicity induced by the pesticides imazalil, thiacloprid and clothianidin alone or in binary mixtures in a 28-day study in female Wistar rats
Authors: Alarcan Jimmy , Sprenger Heike , Waizenegger Julia , Lichtenstein Dajana , Luckert Claudia , Marx-Stoelting Philip , Lampen Alfonso , Braeuning Albert 
Published: January 2021

AbstractCo-occurrence of pesticide residues in food commodities raises a potential safety issue as their mixture effects on human health are largely unknown. In a previous study, we reported the toxicological effects (pathology and histopathology) of imazalil (IMZ), thiacloprid (THI), and clothianidin (CTD) alone and in binary mixtures in a 28-day oral gavage study in female Wistar rats. Five dose levels (up to 350 mg/kg body weight/day) ranging from a typical toxicological reference value to a clear effect dose were applied. In the present study, we undertook a transcriptomics analysis of rat livers by means of total RNA sequencing (RNA-Seq). Bioinformatic data analysis involving Ingenuity Pathway Analysis (IPA) was used to gain mechanistic information on hepatotoxicity-related pathways affected after treatment with the pesticides, alone and in mixtures. Our data show that 2986 genes were differentially regulated by CTD while IMZ and THI had effects on 194 and 225 genes, respectively. All three individual compounds shared a common subset of genes whose network is associated with xenobiotic metabolism and nuclear receptor activation. Similar networks were retrieved for the mixtures. Alterations in the expression of individual genes were in line with the assumption of dose addition. Our results bring new insight into the hepatotoxicity mechanisms of IMZ, THI, and CTD and their mixtures.
Classic serotonergic psychedelics for mood and depressive symptoms: a meta-analysis of mood disorder patients and healthy participants
Authors: Galvão-Coelho Nicole L. , Marx Wolfgang , Gonzalez Maria , Sinclair Justin , de Manincor Michael , Perkins Daniel , Sarris Jerome 
Published: January 2021

Abstract
Rationale
Major depressive disorder is one of the leading global causes of disability, for which the classic serotonergic psychedelics have recently reemerged as a potential therapeutic treatment option.

Objective
We present the first meta-analytic review evaluating the clinical effects of classic serotonergic psychedelics vs placebo for mood state and symptoms of depression in both healthy and clinical populations (separately).

Results
Our search revealed 12 eligible studies (n = 257; 124 healthy participants, and 133 patients with mood disorders), with data from randomized controlled trials involving psilocybin (n = 8), lysergic acid diethylamide ([LSD]; n = 3), and ayahuasca (n = 1). The meta-analyses of acute mood outcomes (3 h to 1 day after treatment) for healthy volunteers and patients revealed improvements with moderate significant effect sizes in favor of psychedelics, as well as for the longer-term (16 to 60 days after treatments) mood state of patients. For patients with mood disorder, significant effect sizes were detected on the acute, medium (2–7 days after treatment), and longer-term outcomes favoring psychedelics on the reduction of depressive symptoms.

Conclusion
Despite the concerns over unblinding and expectancy, the strength of the effect sizes, fast onset, and enduring therapeutic effects of these psychotherapeutic agents encourage further double-blind, placebo-controlled clinical trials assessing them for management of negative mood and depressive symptoms.
Diagnostic Performance of a Panel of miRNAs (OsteomiR) for Osteoporosis in a Cohort of Postmenopausal Women
Authors: Kerschan-Schindl K. , Hackl M. , Boschitsch E. , Föger-Samwald U. , Nägele O. , Skalicky S. , Weigl M. , Grillari J. , Pietschmann P. 
Published: January 2021

AbstractA specific signature of 19 circulating miRNAs (osteomiRs) has been reported to be associated with fragility fractures due to postmenopausal osteoporosis. However, it is unknown whether osteoporotic fractures or low BMD phenotypes are independently contributing to changes in osteomiR serum levels. The first aim was to characterize the abundance, sensitivity to hemolysis, and correlation of osteomiR serum levels, the second objective to evaluate the diagnostic accuracy of osteomiRs for osteoporosis according to the WHO criteria and on basis of major osteoporotic fracture history. Fifty postmenopausal women with osteoporosis (with or without fragility fracture) and 50 non-osteoporotic women were included in this cross-sectional study. The diagnostic performance of osteomiRs for osteoporosis based on the WHO definition or fracture history was evaluated using multiple logistic regression and receiver-operator curve (AUC) analysis. The osteomiR® signature is composed of four clusters of miRNAs providing good performance for the diagnosis of osteoporosis in postmenopausal women defined by WHO criteria (AUC = 0.830) and based on history of major osteoporotic fractures (AUC = 0.834). The classification performance for the WHO criteria and for fracture risk is driven by miR-375 and miR-203a, respectively. OsteomiRs, a signature of 19 emerging miRNA bone biomarkers, are measurable in human serum samples. They constitute a panel of independent bone and muscle biomarkers, which in combination could serve as diagnostic biomarkers for osteoporosis in postmenopausal women.
Water and Life: The Medium is the Message
Authors: Frenkel-Pinter Moran , Rajaei Vahab , Glass Jennifer B. , Hud Nicholas V. , Williams Loren Dean 
Published: January 2021

AbstractWater, the most abundant compound on the surface of the Earth and probably in the universe, is the medium of biology, but is much more than that. Water is the most frequent actor in the chemistry of metabolism. Our quantitation here reveals that water accounts for 99.4% of metabolites in Escherichia coli by molar concentration. Between a third and a half of known biochemical reactions involve consumption or production of water. We calculated the chemical flux of water and observed that in the life of a cell, a given water molecule frequently and repeatedly serves as a reaction substrate, intermediate, cofactor, and product. Our results show that as an E. coli cell replicates in the presence of molecular oxygen, an average in vivo water molecule is chemically transformed or is mechanistically involved in catalysis ~ 3.7 times. We conclude that, for biological water, there is no distinction between medium and chemical participant. Chemical transformations of water provide a basis for understanding not only extant biochemistry, but the origins of life. Because the chemistry of water dominates metabolism and also drives biological synthesis and degradation, it seems likely that metabolism co-evolved with biopolymers, which helps to reconcile polymer-first versus metabolism-first theories for the origins of life.
Anatomy of teleost fish immune structures and organs
Authors: Bjørgen Håvard , Koppang Erling Olaf 
Published: January 2021

AbstractThe function of a tissue is determined by its construction and cellular composition. The action of different genes can thus only be understood properly when seen in the context of the environment in which they are expressed and function. We now experience a renaissance in morphological research in fish, not only because, surprisingly enough, large structures have remained un-described until recently, but also because improved methods for studying morphological characteristics in combination with expression analysis are at hand. In this review, we address anatomical features of teleost immune tissues. There are approximately 30,000 known teleost fish species and only a minor portion of them have been studied. We aim our review at the Atlantic salmon (Salmo salar) and other salmonids, but when applicable, we also present information from other species. Our focus is the anatomy of the kidney, thymus, spleen, the interbranchial lymphoid tissue (ILT), the newly discovered salmonid cloacal bursa and the naso-pharynx associated lymphoid tissue (NALT).