bluuebunny/crossref_metadata_2025_split huggingface dataset:
AstroSat Study of the Globular Cluster NGC 2298: Probable Evolutionary Scenarios of Hot Horizontal Branch Stars
Authors: Rani Sharmila , Pandey Gajendra , Subramaniam Annapurni , Chung Chul , Sahu Snehalata , Kameswara Rao N. 
Published: December 2021

Abstract
We present the far-UV (FUV) photometry of images acquired with UVIT on AstroSat to probe the horizontal branch (HB) population of the Galactic globular cluster NGC 2298. UV-optical color–magnitude diagrams (CMDs) are constructed for member stars in combination with Hubble Space Telescope UV Globular Cluster Survey data for the central region and Gaia and ground-based photometric data for the outer region. A blue HB (BHB) sequence with a spread and four hot HB stars are detected in all FUV-optical CMDs and are compared with theoretical updated BaSTI isochrones and synthetic HB models with a range in helium abundance, suggesting that the hot HB stars are helium enhanced when compared to the BHB. The estimated effective temperature, radius, and luminosity of HB stars, using the best spectral energy distribution fits, were compared with various HB models. BHB stars span a temperature range from 7500 to 12,250 K. Three hot HB stars have 35,000–40,000 K, whereas one star has around ∼100,000 K. We suggest the following evolutionary scenarios: two stars are likely to be the progeny of extreme HB (EHB) stars formed through an early hot-flasher scenario, one is likely to be an EHB star with probable helium enrichment, and the hottest HB star, which is about to enter the white dwarf cooling phase, could have evolved from the BHB phase. Nevertheless, these are interesting spectroscopic targets to understand the late stages of evolution.
Domains of Magnetic Pressure Balance in Parker Solar Probe Observations of the Solar Wind
Authors: Ruffolo David , Ngampoopun Nawin , Bhora Yash R. , Thepthong Panisara , Pongkitiwanichakul Peera , Matthaeus William H. , Chhiber Rohit 
Published: December 2021

Abstract
The Parker Solar Probe (PSP) spacecraft is performing the first in situ exploration of the solar wind within 0.2 au of the Sun. Initial observations confirmed the Alfvénic nature of aligned fluctuations of the magnetic field
B
and velocity
V
in solar wind plasma close to the Sun, in domains of nearly constant magnetic field magnitude ∣
B
∣, i.e., approximate magnetic pressure balance. Such domains are interrupted by particularly strong fluctuations, including but not limited to radial field (polarity) reversals, known as switchbacks. It has been proposed that nonlinear Kelvin–Helmholtz instabilities form near magnetic boundaries in the nascent solar wind leading to extensive shear-driven dynamics, strong turbulent fluctuations including switchbacks, and mixing layers that involve domains of approximate magnetic pressure balance. In this work we identify and analyze various aspects of such domains using data from the first five PSP solar encounters. The filling fraction of domains, a measure of Alfvénicity, varies from median values of 90% within 0.2 au to 38% outside 0.9 au, with strong fluctuations. We find an inverse association between the mean domain duration and plasma β. We examine whether the mean domain duration is also related to the crossing time of spatial structures frozen into the solar wind flow for extreme cases of the aspect ratio. Our results are inconsistent with long, thin domains aligned along the radial or Parker spiral direction, and compatible with isotropic domains, which is consistent with prior observations of isotropic density fluctuations or flocculae in the solar wind.
La recherche de trop ? Configurations et enjeux de la surétude
Authors: Chossière Florent , Desvaux Pierre , Mahoudeau Alex 
Published: December 2021

Malgré son caractère exceptionnel, la surétude fonctionne comme un miroir particulièrement efficace de la recherche universitaire. Réfléchir aux multiples enjeux soulevés par les phénomènes de surétude permet de repenser, sous un angle particulier, les normes de la recherche en train de se faire, de la définition d’un objet d’étude en amont jusqu’aux modalités de restitution des résultats en aval, ainsi que de révéler des impensés des pratiques d’enquête. En proposant d’aborder la surétude non pas comme l’effet de « mauvaises pratiques » de terrain mais comme un effet structurant de la recherche au travail, ce dossier entend ainsi proposer des pistes de réflexion et ouvrir des discussions sur cette thématique qui fait l’objet d’une attention croissante dans le monde anglophone, mais qui reste encore rarement abordée dans la littérature francophone, tout en proposant de valoriser les apports de la géographie pour sa compréhension. Nous nous attardons sur trois phénomènes marquant les dynamiques de surétude : l’apparition d’une « industrie » locale de la recherche, le phénomène de « fatigue » de la recherche, ainsi que les effets de dissimulation causés par ces dynamiques. Nous discutons aussi des implications méthodologiques d’un tel phénomène.
Enquêter les personnes trans en géographie. Des méthodes participatives pour répondre aux enjeux de la surétude ?
Authors: Bonté Milan 
Published: December 2021

La situation de surétude des personnes trans se traduit, en France et au Royaume-Uni, par un double enjeu : d’un côté, il existe une forme de sursollicitation des communautés trans dans le cadre d’enquêtes académiques ou non-académiques, et de l’autre, paradoxalement, de véritables lacunes dans les savoirs trans . L’objet de cet article est de commenter la mise en place d’un protocole d’enquête participative visant à répondre à ces enjeux, déployé dans le cadre d’une thèse en géographie, pour en proposer un bilan critique. La lourdeur des méthodes collaboratives mises en place limite les retombées positives de telles méthodes pour les communautés enquêtées comme pour la recherche. Cela alimente la surcharge des communautés tout en écartant les recherches les moins institutionnalisées. La violence quotidienne vécue par les populations minoritaires est décuplée par l’implication des participant·e·s dans l’analyse de leurs propres vécus. Un chercheur ou une chercheuse membre de la population étudiée se retrouve enfin aux prismes d’injonctions communautaires et académiques contradictoires.
Établissement, entreprise ou groupe – La négociation d’entreprise en quête de ses espaces
Authors: Peskine Elsa 
Published: December 2021

L’ordonnancement des accords collectifs de niveaux différents a été en particulier pensé et décrit dans les rapports entre l’entreprise et la branche. Mais le regard peut s’orienter également sur un autre versant et embrasser l’ordonnancement des niveaux que l’on peut qualifier d’organisationnels en ce qu’ils constituent des espaces de négociation propres à l’organisation productive. Dans la détermination des lieux de déploiement de la capacité d’autorégulation et dans l’agencement des normes conventionnelles, se joue alors une certaine construction et structuration de l’organisation productive. À cet égard, le droit positif est le tableau d’une évolution marquante. D’une part, s’esquisse une diversification des niveaux de conclusion des accords collectifs. À l’établissement et à l’entreprise s’est ajouté le groupe, et même le niveau de « l’interentreprises ». D’autre part, cette diversification s’accompagne, non pas d’une répartition matérielle des compétences normatives distribuées entre chaque niveau, mais d’une liberté offerte aux interlocuteurs sociaux de choisir le niveau qu’ils jugent le plus approprié pour leur négociation par la création d’une forme de fongibilité des accords. L’accord collectif d’entreprise devient une catégorie générique englobant l’accord d’établissement, l’accord d’entreprise au sens strict, et l’accord de groupe. Cette liberté va jusqu’à offrir la possibilité aux parties d’organiser la prévalence de l’accord conclu au niveau centralisé sur l’accord de proximité.
La production cinématographique en négociation : la convention collective de branche comme cadre d’une logique de projets
Authors: Zarka Samuel 
Published: December 2021

La production cinématographique en France se caractérise par une logique de projets profondément hétérogènes en matière de moyens et de budget. À cet égard, il est remarquable que la branche se soit constituée en espace majeur de négociation des normes applicables, notamment en ce qui concerne les salaires des équipes techniques, c’est-à-dire des réalisateurs, opérateurs, décorateurs, etc. Alors même que l’orientation générale des réformes du code du travail, depuis les années 1980, a tendu à favoriser la négociation au niveau de l’entreprise afin d’accompagner les variations productives, ce niveau de négociation est déserté par le cinéma. Visant à élucider ce paradoxe, l’hypothèse de cet article tient précisément dans l’idée que le renouvellement indéfini de projets variés requiert d’établir des repères d’action généraux, dont la branche fournit le cadre. Dès lors, penser la négociation collective permettrait moins de penser l’« entreprise » comme une entité stabilisée qu’une activité productive éminemment fluide, où le droit négocié jour un rôle structurant.
Iodine-125 Plaque Radiotherapy for Retinoblastoma Recurrence Following Intra-arterial Chemotherapy
Authors: Ruben Megan , Eiger-Moscovich Maya , Yaghy Antonio , Tadepalli Sameeksha , Shields Carol L. 
Published: December 2021

Purpose:
To assess the efficacy and toxicity of Iodine-125 (I-125) plaque radiotherapy for retinoblastoma following intra-arterial chemotherapy (IAC).

Methods:
Clinical records of patients with retinoblastoma who received I-125 plaque radiotherapy after IAC at the Ocular Oncology Service at Wills Eye Hospital between December 1, 2009 and April 30, 2020, were retrospectively reviewed.

Results:
Forty-one retinoblastomas in 41 eyes of 41 patients were treated with I-125 plaque radiotherapy after IAC at a median age of 32 months. The indication for plaque radiotherapy was solid tumor recurrence with or without overlying subretinal/vitreous seeds (n = 33, 80%), subretinal seeds alone (n = 6, 15%), and vitreous seeds alone (n = 2, 5%). The median irradiated basal diameter and thickness was 9 and 4 mm, respectively. Mean radiation dose to tumor apex was 3,483 centigray (cGy) delivered at mean rate of 35 cGy/hr. The irradiated site was controlled in 39 eyes (95%) at a median of 20 months after plaque radiotherapy for solid tumor (31 of 33, 94%), subretinal (6 of 6,100%), and vitreous seeds (2 of 2, 100%). A subgroup of tumors occurring within an ischemic retinal/choroidal field was identified on fluorescein angiography (n = 24) and demonstrated control in 22 of 24 (92%). Using Kaplan-Meier analysis, radiation complications at 2 years included vitreous hemorrhage (37%), retinopathy (28%), papillopathy (18%), and cataract (18%). Five eyes (12%) were enucleated for recurrence outside the irradiated area, chronic vitreous hemorrhage, and/or total retinal detachment.

Conclusions:
Iodine-125 plaque radiotherapy provided 95% control for retinoblastoma tumors that failed IAC, including those in ischemic fields untreatable with further chemotherapy. Radiation complications should be anticipated in eyes exposed to substantial chemotherapy.

[
J Pediatr Ophthalmol Strabismus
. 2022;59(3):164–171.]
Treatment of Advanced Coats' Disease With Combination Therapy of Laser Photocoagulation, Intravitreal Ranibizumab, and Sub-Tenon Methylprednisolone Acetate
Authors: Petroni Sergio , Catena Gino , Iarossi Giancarlo , Federici Matteo , Zinzanella Gaetano , Parrilla Rosa , Valente Paola , Buzzonetti Luca 
Published: December 2021

Purpose:
To investigate the efficacy of combination therapy with laser photocoagulation, intravitreal ranibizumab, and sub-Tenon methylprednisolone acetate in patients presenting with advanced Coats' disease.

Methods:
This was a retrospective analysis of 16 patients who underwent laser photocoagulation combined with intravitreal ranibizumab and sub-Tenon methylprednisolone acetate between 2008 and 2017. The primary outcome was anatomic success and the secondary outcomes were globe preservation and final visual acuity.

Results:
The average age at surgery was 5.12 ± 2.7 years (range: 3 to 10 years). The mean follow-up time was 45.43 ± 29.01 months (range: 12 to 108 months). Of the 16 patients (16 eyes) reviewed, 6 patients had stage 3A and 10 patients had stage 3B Coats' disease. The mean number of applications was 10 (range: 4 to 18). Globe preservation was achieved in all patients. Final visual acuity outcomes were satisfactory: 20/20 to 20/50 in 2 patients, 20/60 to 20/100 in 1 patient, and 20/200 or worse in 13 patients.

Conclusions:
Intravitreal ranibizumab used in combination with laser photocoagulation and sub-Tenon methylprednisolone acetate could be an effective treatment option for patients with advanced Coats' disease. The combined therapy achieved anatomical success, globe preservation, and reasonable visual acuity outcomes.

[
J Pediatr Ophthalmol Strabismus
. 2022;59(3):187–191.]
DESAMPARO E AÇÕES ESPECÍFICAS DE CUIDADOS COM UM ADOLESCENTE NA REDE PÚBLICA
Authors: Màris Campos Guerra Andréa , Da Silva Januzzi Mônica Eulália , Franco Ferrari Ilka 
Published: December 2021

Este trabalho apresenta dados preliminares de pesquisa pós-doutoral que investiga, a partir da psicanálise, a noção de ‘desamparo’ em jovens em situação de vulnerabilidade, na busca por ‘ações específicas’ de cuidado na prática institucional em dispositivos de políticas públicas. Partimos da interface entre psicanálise e direito, bem como da supervisão de caso sob ação da Justiça Restaurativa. Analisamos, pela metodologia do caso único, um caso de adolescente sob medida protetiva e socioeducativa, do qual são extraídas duas observações orientadoras: a dimensão da transmissão e filiação e do ‘desamparo’ e da ‘ação específica’ na adolescência. Como resultado, sistematizamos quatro lógicas de orientação para composição da ‘ação específica’: o sujeito e a dimensão simbólica, o sujeito e o circuito pulsional, a implicação e a retificação no campo do Outro, e as inflexões sobre a equipe. Concluímos que o desamparo é uma chave de leitura psicanalítica para a noção de vulnerabilidade e que a supervisão institucional favorece a construção melhor orientada para a ação específica de cuidados.
Palavras-chave: Desamparo; ação específica; adolescência.
The effect of medicarpin on PTEN/AKT signal pathway in head and neck squamous cell carcinoma
Authors: Yiğin Aysel Kalayci , Donmez Huseyin , Hitit Mustafa , Seven Sena , Eser Nadire , Kurar Ercan , Seven Mehmet 
Published: December 2021

Background/Aim:
We aimed to investigate the in vitro modulating effects of medicarpin on the PI3K/AKT signal pathway gene expressions in head and neck squamous cell carcinoma (HNSCC).

Materials and Methods:
The effect of medicarpin on PTEN and other associated genes in the PTEN/AKT signal pathway was investigated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, real-time quantitative polymerase chain reaction, and Western blot analysis in the SCCL-MT1 (HNSCC) and control (HEK-293) cell lines.

Results:
The IC50 dose was 80 μM as a result of medicarpin treatment on HNSCC cells (P = 0.0006). It was found that PTEN and AKT gene expressions increased after the medicarpin administration while PDK1 gene expression was decreased in SCCL-MT1 cells (P = 0.0002, P = 0.0003, and P = 0.05, respectively). Protein expression results showed that medicarpin-treated cells significantly increased in pAKT (P = 0.024), pPTEN (P = 0.032), and decreased pPDK1 (P = 0.059) in SCCL-MT1.

Conclusions:
Our data show that medicarpin modulates HNSCC cells by increasing the PTEN and decreasing PDK1 expressions. PDK1 gene expression effects mTOR pathway which may increase AKT gene. Our study suggests that both medicarpin extracts combination with the HNSCC drug may be more effective in cancer treatment. Future prospective studies that integrate molecular and pharmacogenetic studies are crucial for revealing the mechanism and preventive medical efforts.
Evaluation of Outcome of Halifax Nail and Proximal Femoral Nail Antirotation-Asia in Management of Proximal Femoral Fractures – A Prospective Comparative Study
Authors: Das Pinaki , Karmakar Arnab 
Published: December 2021

Objective:
The objective of the study is to evaluate and compare the results of Halifax and proximal femoral nail antirotation-Asia (PFNA II) in proximal femur fractures.

Methods:
From December 2018 to August 2020, 30 proximal femur fracture nailing were performed. After applying the exclusion criteria, there were 24 patients to be evaluated. The patients were divided into two groups: Halifax group and PFNA II group. The scoring system used for clinical evaluation was Harris hip Score.

Results:
The follow-up period in both the groups was at least 6 months. The proportion of patients with improvements of Harris hip score at different time intervals of the patients treated with Halifax nail was marginally higher than that of the patients treated with Halifax and PFNA II nail but it was not significant (P > 0.05).

Conclusion:
No statistically significant difference was found between Halifax nail and Halifax and PFNA II nail in surgeries done at this particular institution after comparative analysis of Harris hip scores and other parameters.
Nghiên cứu kết quả điều trị thai ngừng tiến triển trong ba tháng đầu bằng Misoprostol
Authors: Bùi Thị Như Quỳnh , Võ Văn Đức , Lê Minh Tâm 
Published: December 2021

Mục tiêu: So sánh hiệu quả của hai phác đồ trong tống thai nội khoa dùng cho thai ngừng tiến triển nhỏ hon 12 tuần: 1- phác đồ Misoprostol đặt âm đạo với phác đồ 2- Misoprostol ngậm dưới lưỡi.
Thiết kế nghiên cứu: mô tả cắt ngang Phương pháp: Trong thời gian từ tháng 12/2015 đến 12/2016, chúng tôi tiến hành nghiên cứu 188 trường hợp thai ngừng tiến triển ≤ 12 tuần tại Khoa Sản Bệnh viện Trường Đại học Y Dược Huế. Bệnh nhân chia ngẫu nhiên làm 2 nhóm: (1) tống thai bằng Misoprostol đường đặt âm đạo, (2) tống thai bằng Misoprostol ngậm dưới lưỡi.
Kết quả: Tỷ lệ thành công chung là 97,9%. Không có sự khác biệt giữa hai nhóm Misoprostol đặt âm đạo và Misoprostol ngậm dưới lưỡi (p > 0,05). Thời gian xuất hiện triệu chứng khi ngậm Misoprostol dưới lưỡi (2,8 ± 1,3 giờ) nhanh hơn khi đặt âm đạo (3,3 ± 1,4) và thời gian tống thai trung bình ở nhóm Misoprostol ngậm dưới lưỡi (9,2 ± 3,8giờ) cũng nhanh hơn so với nhóm Misoprostol đặt âm đạo (11,3 ± 4,1giờ) và sự khác biệt có ý nghĩa thống kê (p < 0,05). Sự khác biệt không có ý nghĩa về tỷ lệ sẩy thai hoàn toàn và không hoàn toàn. Tác dụng phụ hay gặp khi đặt âm đạo là tiêu chảy (12,8%). Trong khi đó ở nhóm Misoprostol đường ngậm dưới lưỡi, tê niêm mạc dưới lưỡi và buồn nôn, nôn là tác dụng phụ bị than phiền nhiều nhất.
Kết luận: Cả Misoprostol đường ngậm dưới lưỡi và đặt âm đạo đều hiệu quả trong tống thai ngừng tiến triển ≤ 12 tuần. Tuy nhiên Misoprostol ngậm dưới lưỡi dường như tống thai nhanh hơn và là đường dùng có tỷ lệ hài lòng cao hơn.
Đánh giá các yếu tố ảnh hưởng đến sự thay đổi của Anti-Mullerian Hormone sau mổ nội soi bóc nang lạc nội mạc tử cung tại buồng trứng
Authors: Nguyễn Thị Thu Hà , Nguyễn Đức Hinh , Nguyễn Duy Ánh 
Published: December 2021

Mục tiêu: Xác định các yếu tố ảnh hưởng đến sự thay đổi AMH sau mổ nội soi bóc nang lạc nội mạc tử cung tại buồng trứng. Đối tượng: 100 bệnh nhân được mổ nội soi bóc nang LNMTC tại buồng trứng.
Phương pháp nghiên cứu: Nghiên cứu theo dõi dọc.
Kết quả: nồng độ AMH trung bình giảm 47,94% sau mổ, sự thay đổi này không phụ thuộc vào các yếu tố: số lần có thai, số con, tình trạng vô sinh hay nồng độ CA125, các yếu tố ảnh hưởng đến sự thay đổi AMH sau mổ là vị trí nang ở một bên hay hai bên buồng trứng, kích thước nang lạc nội mạc tử cung, điểm rASRM, giai đoạn LNMTC, nồng độ AMH trước mổ và tuổi.
Kết luận: Nồng độ AMH giảm có ý nghĩa thống kê sau mổ nội soi bóc nang LNMTC tại buồng trứng phụ thuộc vào nhiều yếu tố trước và trong mổ.
IDENTIFICATION OF FORMALDEHYDE IN UNBRANDED WET NOODLES AT TRADITIONAL MARKETS OF TAMBUN SELATAN USING TEST KIT METHODS AND UV-VIS SPECTROPHOTOMETRY
Authors: Rarabiella Wilis , Sari Elfira Maya , Nurfajriah Siti 
Published: December 2021

Introduction: Wet noodles are flour-based foods that are widely consumed by the community because of their easy processing. The high water content in wet noodles makes the noodles not last long. In fact, there is still a preservative in wet noodles that is not used, namely formaldehyde. The purpose of this study was to determine whether there was formaldehyde in unbranded wet noodles in the Traditional Market of South Tambun District and to determine the level of formaldehyde in unbranded noodles in the Traditional Market of South Tambun District.
Method: This research was conducted at the STIKes Mitra Keluarga laboratory. The type of research used is descriptive. There are 7 samples taken from 4 different markets. The sample was tested using a formaldehyde test kit and resulted in 6 positive formaldehyde samples. According to SNI, formaldehyde should not be in wet noodles. So that the results of the 6 samples did not meet the quality requirements of wet noodles.
Results: Furthermore, the positive sample was determined using a UV-VIS spectrophotometer and Nash reagent. The lowest level of formaldehyde is 18.61 mg/L while the highest level is 738.45 mg/L.
Conclusion: First, the regulation is not yet known by the producers because it is classified as traditional. Second, there is no good control from authorized institutions or officers. Third, the lack of guidance for producers
Estudio espectroscópico de nanopartículas de plata pasivadas con el polímero conjugado PEDOT:PSS
Authors: Valdivia Julio Cesar , Pérez Analuisa , Rodríguez Geraldina , Hurtado Gilberto , Moggio Ivana , Arias Eduardo , Zappia Stefania , Destri Silvia , Scavia Guido , Alloisio Marina , Castañeda Adalí 
Published: December 2021

Se sintetizaron nanopartículas de plata AgNPs a partir de nitrato de plata, empleando borohidruro de sodio como agente reductor y poli(etilendioxitiofeno):poli(estiren sulfonato de sodio), PEDOT:PSS, como estabilizador. Se variaron los siguientes parámetros de síntesis: 1) contenido relativo entre PEDOT y PSS, utilizando tres formulaciones comerciales; y 2) relación molar entre sal de plata y agente reductor. Por espectroscopia UV-Vis, se corroboró la formación de las AgNPs mediante la banda plasmónica a ~ 400 nm, además se observaron cambios espectrales para el PEDOT cuando se utilizan las formulaciones con mayor contenido de PEDOT, y relación sal/agente reductor de ~1, lo cual de acuerdo con los espectros Raman se asocia con un cambio conformacional del PEDOT hacia una estructura más benzenoide. En las demás condiciones, las propiedades espectroscópicas son similares a las de nanopartículas preparadas con puro PSS. Con base en los resultados, se plantea que las AgNPs se estabilizan con el PSS en exceso, afuera de los dominios PEDOT:PSS, cuando la formulación tiene más contenido de PSS o empleando bajas cantidades de NaBH4. Al incrementar el contenido de NaBH4, las AgNPs se forman también adentro de los dominios. El mecanismo de estabilización permite así modular las propiedades ópticas y eléctricas de las NPs.