bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study on bacteriological profile and antibiotic susceptibility in diabetic foot infection in a teaching hospital, Telangana
Authors: Pothati Divya , Kiran B. Uday 
Published: August 2021

Diabetic foot is one of the most significant complications of diabetes, Chronic infections are caused by Enterococci, various Enterobacteriaceae obligate anaerobes, Pseudomonas aeruginosa. To study bacteriological profile and antibiotic susceptibility in diabetic foot infection. Cross sectional study was done in 110 diabetic foot infection cases in the Department of Microbiology, Prathima Institute of Medical Sciences, Nagunuru, Karimnagar, Telangana. The grading of diabetic foot ulcers was done according to Wagner’s Classification system. The samples were collected from the exudates and ulcers. Gram stain was done and standard protocol for culture and sensitivity was followed for all the cases.A total of 110 cases were studied. The patient age ranged from 35 to 75 years and the male to female ratio was 2:1. Out of 110 isolates, 72.7% isolates were Gram negative bacilli with P. aeruginosa 31.8% being the predominant followed by E.coli 27.2%, K.pneumoniae 10%, P.mirabilis 4.5%, S.aureus 12.7% was the predominant isolate followed by Enterococci spp 4.5% and Coagulase negative staphylococci (CONS) 4.5% and S. pyogenes were 5.4%. Both Gram positive cocci and Gram negative bacilli can cause dia­betic foot infections and this study showed a preponderance of Gram negative bacilli. Early culture and sensitivity test of the bacterial isolates helps in guiding the treatment plan
MENINGKATKAN SIKAP TOLERANSI PADA DOMAIN AFEKTIF, KOGINITIF DAN PERILAKU SISWA DALAM INTEGRASI PENDIDIKAN AGAMA KRISTEN DAN BUDI PEKERTI MELALUI PENERAPAN METODE FILMED ROLE-PLAY [INCREASING TOLERANCE IN STUDENTS' AFFECTIVE, COGNITIVE, AND BEHAVIOUR DOMAINS THROUGH THE INTEGRATION OF CHRISTIANITY AND MORAL STUDIES USING THE FILMED ROLE-PLAY METHOD]
Authors: Stephanie Stephanie 
Published: August 2021

<div>Indonesia is a religion based country. Religion studies should be positioned as school’s curriculum priority, both in public and private school. Integrated Christianity and moral studies might be the solution of conflicts within family, school, community, both national and international societies. One of many values that urgently needs to be promoted is an attitude of tolerance in facing our multicultural society. School as an educational institution has an important role in teaching tolerance skill to students as early age. One of the challenges is finding the right method to deliver the abstract concepts to children who are in the stage of pre-operational concrete. This research has done an introductionary study towards the bullying case that happened earlier in the researchers workplace 4<sup>th</sup> and 5<sup>th</sup> graders within 4 months. Therefore, this research address the urgency of an integrated curriculum of Christianity studies with moral studies practices, specifically on multicultural values through experiential learning with filmed role-play. Research was conducted in XYZ School for primary 3, 4 and 5. This instructional strategy resulted in increase of attitude of tolerance both in cognitive and behavior domain, but has no increase in the affective domain. All respondents agree by implementing filmed role-play has contributed to their deeper understanding towards the concept of tolerance.</div>
Pengaruh Pendekatan M-APOS Terhadap Kemampuan Penalaran Matematis Siswa SMP Negeri di Kota Tangerang
Authors: Noviana Widyah , Suyono Suyono , Hakim Lukman El 
Published: August 2021

Penelitian ini bertujuan untuk mengetahui pengaruh pendekatan M-APOS terhadap kemampuan penalaran matematis siswa dalam belajar matematika. Penelitian ini dilaksanakan di SMP Negeri 13 Tangerang dan SMP Negeri 4 Tangerang tahun ajaran 2015-2016. Metode penelitian yang digunakan adalah metode quasi experiment. Sampel penelitian diperoleh melalui teknik random sampling sebanyak 100 siswa yang terbagi menjadi 50 siswa kelas eksperimen dan 50 siswa kelas kontrol. Instrumen penelitian telah diuji cobakan kepada 36 siswa kelas VIII di SMP Negeri 13 Tangerang. Setelah melalui proses uji validitas dengan rumus Product Moment didapat 7 soal yang valid dari 7 soal yang ada serta reliabel dengan rumus Alpha Cronbach. Sebelum data di analisis, dilakukan uji prasyarat yaitu uji normalitas menggunakan uji Liliefors dan uji homogenitas menggunakan Levene-Test. Setelah dilakukan perhitungan didapat bahwa data kedua kelompok berdistribusi normal dan homogen. Pengujian hipotesis dengan menggunakan uji-t diperoleh dan 1,6637. Karena maka ditolak. Simpulannya adalah terdapat perbedaan kemampuan penalaran matematis siswa dengan menggunakan pendekatan M-APOS dan pembelajaran ekspositori. Hal ini juga menyatakan bahwa kemampuan penalaran matematis siswa yang diberi perlakuan pendekatan M-APOS lebih tinggi dibandingkan kemampuan penalaran matematis siswa yang diberi pendekatan ekspositori.
Pre-Jurassic Formation Lithological Composition and Reservoir Characteristic Variation Analysis. Core and Field Tests Analysis in Frolovsky and Shaimsky Petroliferous Regions
Authors: Zadorozhnyaya Irina 
Published: August 2021

Abstract
Analysis of the lithology of rocks of the pre-Jurassic complex and changes in the reservoir properties of rocks is one of the most important and difficult tasks for the formation of a petrophysical model for the interpretation of well logging data. Despite the long history of geological and geophysical study of deposits of the pre-Jurassic complex, a number of issues related to the reflection in the geophysical parameters of rocks and characteristics of reservoir properties have been studied insufficiently. This is due to the high variability of the lithological composition, textural and structural heterogeneity of the volcanic-sedimentary strata of the Turin Group.
At present, the sediments of the pre-Jurassic complex are being actively studied - a representative core is purposefully selected, which is studied using an SCAL, including special methods, modern precision electrical, radioactive and acoustic studies are included in the complex of geophysical studies. The results of new studies are a good information base for refining the petrophysical model of an extraordinary object of study.
The aim of this work was to analyze the lithology and reservoir properties of rocks, as well as to identify and classify the main groups of rocks that are possible reservoirs in the sediments of the pre-Jurassic complex within the Frolovsky and Shaimsky petroliferous regions.
Consideration of the Influence of Carbonate Cement on the Accuracy of Prediction of Well Start-Up Flow Rates in Deep Reservoirs of the West Siberian Oil and Gas Basin on the Example of Reservoir U1 Formation
Authors: Mikhaylov Sergey Petrovich , Shtyrlyaeva Anastasia Andreevna 
Published: August 2021

Abstract
Oil reservoirs are often affected by tectonic processes throughout their lifetime. Tectonic processes contribute to the impact on the formation of a number of mechanical and chemical factors. These factors change the composition and structure of the reservoir and this affects the reservoir properties of the reservoir. Deep-seated reservoirs experience a longer and more intense impact of tectonic processes. A more detailed study of the composition and properties of reservoirs for an accurate forecast of reservoir properties and their productivity potential is due to this.
Standard log interpretation methods have been developed based on shallow strata. These methods do not allow taking into account secondary changes in the reservoir and make the calculations of the starting flow rates of wells reliable.
J1 stratum West Wing on Nizhnevartovsky set is a prime example of this.
Diffraction of Partial Temporal Coherence Beam From Multi Slits
Authors: Koushki Ehsan , ALAVI ALi 
Published: August 2021

Abstract
We have generalized the notion of Franhoufer diffraction of temporal coherent light from a single slit to the case of arbitrary n -slits. A general numerical method has been developed for the simulation of the diffraction pattern of multi-slits which is also used to study the effects of coherence length on the diffraction pattern. The diffraction pattern is investigated for different values of recently introduced parameter “decoherence parameter”. It is shown that for multi-slits, the temporal decoherence effects appear for . The results of our study reproduce the previous studies for perfect temporal case, when coherence length tends to infinity.
MEQA-RPL: A Mobility Energy and Queue Aware Routing Protocol for Mobile Nodes in Internet of Things
Authors: cyriac robin , MA Saleem Durai 
Published: August 2021

Abstract
Increase in mobile nodes has brought new challenges to IoT’s routing protocol-RPL. Mobile nodes (MN) bring new possibilities as well as challenges to the network. MN creates frequent route disruption, energy loss and increases end-to-end delay in the network. This could be solved by improving RPL to react faster to route failures through route prediction, while keeping energy expenditure for this process in reasonable limits. In this context a new Mobility Energy and Queue Aware-RPL (MEQA-RPL) is proposed that have the capability to sense route failure and to identify proactively the next possible route before the current route fails. While identifying the next route, MEQA-RPL employs constraint check on energy and queue availability to guarantee QoS for MN and better lifetime for the network. When compared to RPL with mobility support our model reduce average signaling cost by 31%, handover delay by 32% and improve packet delivery ratio by 17%. We run simulations with multiple mobile nodes which have also shown promising results on aforementioned parameters.
Functional Characterization of Lycopene Epsilon-Cyclase Genes in Nicotiana Tabacum
Authors: Song Weina , Wei Fang , Gao Shuwen , Dong Chen , Hao Jianfeng , Jin Lifeng , Li Feng , Wei Pan , Guo Jinggong , Wang Ran 
Published: August 2021

Abstract
Background:Lycopene epsilon-cyclase (ε-LCY) is a key enzyme in the carotenoid biosynthetic pathway (CBP) of higher plants. In previous work, we cloned two Ntε-LCY genes from allotetraploid tobacco (Nicotiana tabacum), Ntε-LCY2 and Ntε-LCY1, and demonstrated the overall effect of Ntε-LCY genes on carotenoid biosynthesis and stress resistance. However, their genetic and functional characteristics require further research in polyploid plants.Results: Here, we used CRISPR/Cas9 to obtain Ntε-LCY2 and Ntε-LCY1 mutants in allotetraploid N.tabacum K326. Ntε-LCY2 and Ntε-LCY1 had similar promoter cis-acting elements, including light-responsive elements. The Ntε-LCY genes were expressed in roots, stems, leaves, flowers, and young fruit, and their highest expression levels were found in leaves. Ntε-LCY2 and Ntε-LCY1 genes responded differently to normal light and high light stress. Both the Ntε-LCY2 and the Ntε-LCY1 mutants had a more rapid leaf growth rate, especially ntε-lcy2-1. The expression levels of CBP genes were increased in the ntε-lcy mutants, and their total carotenoid content was higher. Under both normal light and high light stress, the ntε-lcy mutants had higher photosynthetic capacities and heat dissipation levels than the wild type, and this was especially true of ntε-lcy2-1. The reactive oxygen species content was lower in leaves of the ntε-lcy mutants.Conclusion: In summary, the expression patterns and biological functions of the Ntε-LCY genes Ntε-LCY1 and Ntε-LCY2 differed in several respects. The mutation of Ntε-LCY2 was associated with a greater increase in the content of chlorophyll and various carotenoid components, and it enhanced the stress resistance of tobacco plants under high light.
It’s what you do, Not the way that you do it – Online Versus Face to Face Small Group Teaching in First Year Medicine.
Authors: Torda Adrienne , Shulruf Boaz 
Published: August 2021

Abstract
BackgroundMajor disruptions imposed on medical education by the COVID-19 pandemic and the rapid shift to online teaching in medical programs, necessitated need for evaluation of this format. In this study we directly compared knowledge outcomes, social outcomes, and wellbeing of first year student small group teaching in either face to face (f2f) or online format.MethodsAt the end of the first course of our medical program, students were invited to participate in an online questionnaire with 10 quantitative items and 1 qualitative item. These were analysed using Factor Analysis Pattern Matrix and linear regression to group items and assess relatedness. Qualitative responses were thematized using Qualtrics software (Qualtrics, Provo, UT, USA). Summative assessment results were compared, both between current cohorts to historical cohorts.ResultsFrom a cohort of 298 students there was a 77% response rate. Overall, there were no differences in knowledge gains, either between groups or when compared to historical cohorts. Questionnaire items fell reliably into groups that related to either learning outcomes, social outcomes, or wellbeing. Independent T tests showed that format for teaching (online versus f2f) had an impact on social outcomes but no direct impact on learning outcomes. Linear regression revealed that the social outcomes have a direct impact on wellbeing and almost the double the impact on learning outcomes than mode of learning ie. F2f or online (β=.448 and β=.232 respectively). ConclusionIn this study, we were able to show with statistical strength that social outcomes for students such as engaging with peers and facilitator, contributing to the group, and making friends have a direct impact on wellbeing and indirectly impact learning outcomes (such as motivation, satisfaction, integration of knowledge). In a rapidly changing educational landscape, it is vital that these aspects are a focus of design and delivery of medical education. The data from this study supports the notion that activity design and the expertise of the teacher in facilitating the small group activities, is more important than the mode of educational delivery itself.
Home Environment and Noise Annoyance in a National Sample of Multi-Family Buildings in Sweden- Associations with Stress-Related Symptoms
Authors: Wang Juan , Norbäck Dan 
Published: August 2021

Abstract
Background: Poor acoustic condition at home can have negative health impact. The aim was to investigate home environment factors and stress symptoms associated with noise annoyance. Methods: All adults (≥18 y) registered in selected apartments in Sweden were invited to participate in a questionnaire survey including medical questions and personal factors. Totally 5775 adults participated (response rate 46%). Information on home environment was obtained through an indoor environment questionnaire. Two-level logistic regression models (individual, municipality) were performed to estimate associations.Results: Totally 11.2% reported any frequent noise at home. Voice/radio/TV/music/similar sounds from neighbours (13.2%) and scraping sound/footsteps/thumping from neighbours (16.5%) and road traffic (16.1%). Younger participants reported more noise annoyance and more stress-related symptoms. Females were more sensitive to noise from neighbours and traffic noise causing severe effects. Noise annoyance was related to tiredness, headache and difficulty concentrating (OR=1.70-8.19), and noise annoyance from many sources was related to a higher risk of symptoms. A warmer climate (OR=1.30), buildings constructed from 1961-1985 (OR=1.50-1.85), renting (OR=1.83) and living alone (OR=1.42) were related to more noise annoyance. A warmer climate (OR=1.95), higher municipality population density (OR=1.24), a longer living time (OR=1.34), construction year (1961-1975) (OR=2.42), renting (OR=1.80-2.32), living above ground floor (OR=1.45) and having a bathroom fan (OR=1.84) were associated with increased noise annoyance from neighbours. Factors associated with increased noise annoyance from installations or ventilation/fans/heat pumps included a warmer climate, higher municipality population density, construction year (1961-1995), renting and any mechanical ventilation. Higher municipality population density, construction year (especially 1961-1985) and renting were associated with more noise annoyance from traffic (OR=1.77-3.92). Renting (OR=1.73) and living above ground floor (OR=1.60) were related to more severe traffic noise effects.Conclusions: The present study shows that noise annoyance may cause stress-related symptoms. Younger age, female gender, living alone, a longer living time, a warmer climate, higher municipality population density and building factors (renting, construction period 1961-1975, living above ground floor and mechanical ventilation system) were related to more noise annoyance.
ScLRTC: Imputation for Single-Cell RNA-Seq Data Via Low-Rank Tensor Completion
Authors: Li Zhong , Pan Xiutao , Qin Shengwei , Yu Minzhe , Hu Hang 
Published: August 2021

Abstract
Background: With single-cell RNA sequencing (scRNA-seq) methods, gene expression patterns at the single-cell resolution can be revealed. But as impacted by current technical defects, dropout events in scRNA-seq lead to missing data and noise in the gene-cell expression matrix and adversely affect downstream analyses. Accordingly, the true gene expression level should be recovered before the downstream analysis is carried out. Results: In this paper, a novel low-rank tensor completion-based method, termed as scLRTC, is proposed to impute the dropout entries of a given scRNA-seq expression. It initially exploits the similarity of single cells to build a third-order low-rank tensor and employs the tensor decomposition to denoise the data. Subsequently, it reconstructs the cell expression by adopting the low-rank tensor completion algorithm, which can restore the gene-to-gene and cell-to-cell correlations. ScLRTC is compared with other state-of-the-art methods on simulated datasets and real scRNA-seq datasets with different data sizes. Specific to simulated datasets, scLRTC outperforms other methods in imputing the dropouts closest to the original expression values, which is assessed by both the sum of squared error (SSE) and Pearson correlation coefficient (PCC). In terms of real datasets, scLRTC achieves the most accurate cell classification results in spite of the choice of different clustering methods (e.g., SC3 or t-SNE followed by K-means), which is evaluated by using adjusted rand index (ARI) and normalized mutual information (NMI). Lastly, scLRTC is demonstrated to be also effective in cell visualization and in inferring cell lineage trajectories.Conclusions: a novel low-rank tensor completion-based method scLRTC gave imputation results better than the state-of-the-art tools. Source code of scLRTC can be accessed at https://github.com/jianghuaijie/scLRTC.
Spill-overs and trade-offs for increasing livestock productivity
Authors: Acosta Alejandro , Cicowiez Martin 
Published: August 2021

Abstract
The overarching goal of the United Nations Food Systems Summit is to catalyze action for the transformations needed in food systems to accelerate the progress toward sustainable development goals (SDG). However, given the complexity of these interactions, gains in one area may determine losses in others. Using the Livestock Policy Simulation Model (LPSM), we assessed the effect of enhancing the productivity in the Ethiopian livestock sector by 2030. We show that an increase in productivity has several positive effects on GDP, employment generation, household consumption, and poverty reduction; however, these benefits might come at an environmental cost associated with a total increase in greenhouse gas emissions. Our results have important policy implications, showing that the achievement of some SDG targets could conflict with the accomplishment of others. The analysis illustrates the capacity of LPSM to integrate economic, social, and environmental dimensions while quantifying spillovers and trade-offs.
Research on Characteristic Recognition and Dangerous Prevention While Mining through Collapse Column of Pansan Minefield,China
Authors: Xu Haitao , yang hui , Sun Wenbin , Kong Lingjun , Zhang Peng 
Published: August 2021

Abstract
In order to find out the characteristics of geological isomer exposed in the mining process of 12318 working face in Pansan Mine and grasp its influence law on subsequent coal seams mining, the isomer was firstly determined as the collapse column by means of 3D seismic, transient electromagnetic detection, SYT detection and other methods, and its development characteristics, conductivity and water enrichment were identified.Then FLAC3D numerical simulation software was used to analyze the characteristics of vertical stress and plastic failure zone in different coal seams during mining.Finally, by comparing the ultimate failure depth of floor and the thickness of waterproof layer in the process of each coal seam directly pushing through the collapse column, the risk of water inrush and the prevention are analyzed.The results show that the exposed geological isomer is characterized by weak water-rich collapse column.Under the influence of the mining of the previous coal seam and the activation of the collapse column, the subsequent coal seam is in the low stress area before mining, which increases the floor failure and causes the activation of the collapse column more easily during mining.Coal 5# and 4# can be directly pushed through the collapse column, and coal pillar of sufficient width should be left for coal 1# to prevent the collapse column from activating water inrush.
Na+/H+-Exchanger Family As Novel Prognostic Biomarkers In Colorectal Cancer
Authors: Zhou Xin , Jiang Manman , Liu Zhihong , Xu Mengmeng , Chen Nannan , Wu Ziyu , Gu Changji , Chin Eugene , Yang Xiaodong 
Published: August 2021

Abstract
Background: The acidic characteristics of the tumor microenvironment (TME) are attributed to cancer cells’ needs of metabolism that produce a large amount of H+. In order not to affect its own life activities, it needs to release H+ into the intercellular space through an efficient Na+/H+ exchanger. On account of the intestine whose physiological function is highly dependent on intestinal pH value, NHE family members may play a critical role in the occurrence and development of colorectal cancer (CRC).Methods: TCGA, GEPIA2, ONCOMINE, UALCAN, STRING, TIMER, Cytoscape, TargetScan, ENCORI, LncBase v.2, DNMIVD, HPA and CellMinerTM databases were used in our study.Results: The mRNA expression of SLC9A1, SLC9A2, SLC9A3 and SLC9A9 were evidently lower in COAD compared to normal samples, however, mRNA expression of SLC9A5, SLC9A8 and SLC9B2 were higher. Besides, mRNA expression of NHE family were extremely associated with clinicopathological features, tumor immune microenvironment and stemness score, DNA methylation and patient prognosis in COAD. Moreover, we conjectured that NHE family may play a role through MAPK or ErbB signaling pathway according to the results of GO/KEGG enrichment analysis. At last, we found that NHE family members were key factors of various kinds of cancers.Conclusion: Our study indicated that NHE family was new diagnostic and therapeutic targets for CRC, which could have important significance for the clinical treatment of CRC.