bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diagnostic value of Tc-99m-MIBI SPECT/CT in parathyroid carcinoma with lung metastasis: a case report and literature review
Authors: Zhu Yirong , Wang Lian , You Jiaxi , Deng Shengming , Shi Yizhen , Liu Zengli , Hong Zhihui 
Published: December 2024

PurposeParathyroid carcinoma (PC) is an extremely rare disease, typically presenting with marked elevations of serum calcium concentrations and associated with significantly increased parathyroid hormone (PTH) levels. Although it progresses slowly, approximately25% of PC patients have lung metastases. In the present study, we aimed to evaluate the role of technetium-99m methoxy isobutyl isonitrile (Tc-99m-MIBI; sestamibi) SPECT/CT scintigraphy in the preoperative localization of parathyroid adenomas, incidental metastases findings of PC, and ectopic parathyroid tissue.MethodsWe presented a rare case alongside a review of the relevant literature.ResultsWe described an unusual case of a 25-year-old female patient with co-occurrence of PC and lung metastasis. The primary PC lesion showed no radioactive uptake, while the lung metastasis presented as a hyperfunctioning nodule, successfully localized using Tc-99m-MIBI SPECT/CT and confirmed through surgical and pathological examination.ConclusionsThis case emphasized the uniqueness of Tc-99m-MIBI SPECT/CT imaging in diagnosing PC and metastatic lesions. The appropriate application of this technique may help avert the aggressive clinical progression of PC.
Acquisition of non-contrastive focus in Russian by adult English-dominant bilinguals
Authors: Luchkina Tatiana , Ionin Tania , Goldshtein Maria 
Published: December 2024

This study investigates the acquisition of sentence focus in Russian by adult English-Russian bilinguals, while paying special attention to the relative contribution of constituent order and prosodic expression. It aims to understand how these factors influence perceived word-level prominence and focus assignment during listening.We present results of two listening tasks designed to examine the influence of pitch cues and constituent order on perceived word prominence (Experiment 1) and focus assignment (Experiment 2) during the auditory comprehension of SV[O]F and OV[S]F sentences in Russian. Our findings reveal an asymmetric pattern: monolingual speakers, as a baseline, tend to perceive the nuclear pitch-accented object as more prominent, particularly in the SVO order, whereas bilinguals appear to be less sensitive to the constituent order distinction.Additionally, baseline speakers consistently assign focus to the sentence-final nuclear pitch-accented noun regardless of constituent order. In contrast, bilinguals demonstrate a preference for assigning focus to the sentence-final nuclear-accented object, rather than the sentence-final nuclear-accented subject. A proficiency effect emerged indicative of a more target-like performance among bilinguals with greater proficiency in Russian.
The influence of proactive personality on students’ knowledge sharing: the chain mediating effect of class climate and learning engagement
Authors: Lin Ye , Jin Yongchao , Yang Rui 
Published: December 2024

IntroductionKnowledge sharing is an effective means of knowledge management in colleges and universities, which is of great significance for improving the quality and efficiency of universities and enhancing the balanced development of educational resources. The present study investigated the influence students’ proactive personalities drive knowledge-sharing activities, and examined the significance of class climate and learning engagement as mediating factors, utilizing the perspectives of social exchange theory (SET) and the job demands and resources model (JD-R) .MethodsA convenience sampling method was employed to survey 1,053 Chinese college students, and evaluated them using the Proactive Personality Scale (PPS), Learning Engagement Scale (LES), Class Climate Scale (CCS), and Knowledge Sharing Behavior Scale (KSBS). The structural equation model and bootstrap method to explore the significance of the mediating effect of class climate and learning engagement between proactive personality and knowledge sharing of college students.Results(1) Proactive personality was positively associated with students’ knowledge sharing behavior; (2) Class climate had a significant mediating effect between proactive personality and knowledge sharing behavior of college students, and the mediating effect of class climate is 21.2%; (3) Learning engagement mediated effect between proactive personality and knowledge sharing behavior, and the mediating effect ratio of learning engagement is 8.4%; (4) Class climate and learning engagement play a chain mediating role in the relationship between proactive personality and knowledge sharing behavior of students, and the chain mediating role accounted for 2.1% of the total effect.ConclusionProactive personality exerts a significant impact on students’ knowledge-sharing behaviors. However, this effect is not direct; it is mediated by both class climate and learning engagement. Specifically, students exhibiting higher levels of proactivity are more likely to actively engage in the learning process and foster a positive class climate, which, in turn, enhances their propensity to share knowledge with peers.
Assessment of human emotional reactions to visual stimuli “deep-dreamed” by artificial neural networks
Authors: Marczak-Czajka Agnieszka , Redgrave Timothy , Mitcheff Mahsa , Villano Michael , Czajka Adam 
Published: December 2024

IntroductionWhile the fact that visual stimuli synthesized by Artificial Neural Networks (ANN) may evoke emotional reactions is documented, the precise mechanisms that connect the strength and type of such reactions with the ways of how ANNs are used to synthesize visual stimuli are yet to be discovered. Understanding these mechanisms allows for designing methods that synthesize images attenuating or enhancing selected emotional states, which may provide unobtrusive and widely-applicable treatment of mental dysfunctions and disorders.MethodsThe Convolutional Neural Network (CNN), a type of ANN used in computer vision tasks which models the ways humans solve visual tasks, was applied to synthesize (“dream” or “hallucinate”) images with no semantic content to maximize activations of neurons in precisely-selected layers in the CNN. The evoked emotions of 150 human subjects observing these images were self-reported on a two-dimensional scale (arousal and valence) utilizing self-assessment manikin (SAM) figures. Correlations between arousal and valence values and image visual properties (e.g., color, brightness, clutter feature congestion, and clutter sub-band entropy) as well as the position of the CNN's layers stimulated to obtain a given image were calculated.ResultsSynthesized images that maximized activations of some of the CNN layers led to significantly higher or lower arousal and valence levels compared to average subject's reactions. Multiple linear regression analysis found that a small set of selected image global visual features (hue, feature congestion, and sub-band entropy) are significant predictors of the measured arousal, however no statistically significant dependencies were found between image global visual features and the measured valence.ConclusionThis study demonstrates that the specific method of synthesizing images by maximizing small and precisely-selected parts of the CNN used in this work may lead to synthesis of visual stimuli that enhance or attenuate emotional reactions. This method paves the way for developing tools that stimulate, in a non-invasive way, to support wellbeing (manage stress, enhance mood) and to assist patients with certain mental conditions by complementing traditional methods of therapeutic interventions.
Determinants of sleep quality and their impact on health outcomes: a cross-sectional study on night-shift nurses
Authors: Xiao Qingqing , Huang Xia , Yang Tao , Huang Lei , Li Nan , Wang Jingjun , Huang Junqiang , Huang Yalin , Huang Hao , Wang Ya 
Published: December 2024

PurposeThis study aimed to identify determinants of sleep quality and explore their adverse health outcomes among night-shift nurses in China.MethodThrough convenience sampling, this cross-sectional study enrolled a total of 711 night-shift nurses aged 20-55 years who completed questionnaires from which details regarding their sociodemographic characteristics, health-related indicators and sleep quality based on the Pittsburgh Sleep Quality Index (PSQI) were extracted. A generalized linear regression analysis was then created to identify factors influencing sleep quality. Pearson correlation analysis was used to analyze the relationship between sleep quality and chronic fatigue.ResultsThe prevalence rate of poor sleep quality among night-shift nurses reached as high as 90.1%. Our results showed that education level, years of working experience, quality of make-up sleep before and after night shifts, daily routine and diet were the primary factors affecting sleep quality (p &lt; 0.01). Nurse fatigue had a significant positive correlation with subjective sleep quality, sleep latency, sleep duration, sleep disturbance, medications to sleep, daytime dysfunctions and global sleep quality (p &lt; 0.01). However, nurse sleep efficiency had a significant negative correlation with fatigue (p &lt; 0.01).ConclusionsHigher education level, longer working years, worse quality of make-up sleep before and after night shifts, daily routine and daily diet were risk factors for poor sleep quality among nurses. Poor sleep among night-shift nurses is strongly correlated with chronic fatigue.
Application of targeted high-throughput sequencing as a diagnostic tool for neonatal genetic metabolic diseases following tandem mass spectrometry screening
Authors: Lai Guihua , Gu Qiying , Lai Zhiyong , Chen Haijun , Tu Xiangwen , Chen Junkun , Huang Jungao 
Published: December 2024

BackgroundTandem mass spectrometry (MS/MS) is a crucial technique for detecting inborn errors of metabolism (IEM) in newborns. However, the high false positive rate poses challenges in diagnosing specific types of diseases. Therefore, this study aimed to evaluate the role of targeted next-generation sequencing (NGS) in the accurate diagnosis of positive samples identified through MS/MS screening.MethodsA cohort study of 260,915 newborns was conducted from January 2018 to June 2023 in Ganzhou City, southern China. Heel blood samples were collected within 72 h of birth and subjected to MS/MS analysis. Infants with positive MS/MS results underwent targeted NGS to confirm the diagnosis and identify genetic variants.ResultsAmong 1,265 suspected cases with positive MS/MS results, 73 were confirmed by NGS, and 12 were identified as carriers of recessive diseases. The overall incidence rate was 1 in 3,574, effectively ruling out 94.2% (1,192/1,265) of the MS/MS false-positive. We found 76 variants in 18 genes associated with 15 types of IEM. Among these, 64.47% (49/76) were pathogenic, 10.53% (8/76) were likely pathogenic. Remarkably, 7.89% (6/76) were identified as novel variants. Variants in SLC22A5 (NM_003060.4) gene was most prevalent, accounting for 41% (77/188), with hotspot variants including c.51C &gt; G, c.1400C &gt; G, and c.338G &gt; A.ConclusionTargeted NGS technology can serve as a crucial diagnostic tool for neonatal genetic metabolic diseases following MS/MS screening. Additionally, we identified IEM variant hotspots and some novel variants in our region, which are the underlying causes of disease in patients with IEM.
Swimming pool-associated viral outbreaks in China: causes and solutions
Authors: Huang Zheng 
Published: December 2024

ObjectiveThis study aimed to assess the causes of the swimming pool-associated viral outbreaks in China and discuss the possible preventive measures for the outbreaks.MethodsA systematic search was performed in 4 Chinese and English databases for studies investigating the swimming pool-associated viral outbreaks in China up to June 2024.Results29 outbreaks were included in the review. A median of 89 cases per outbreak was observed among 29 outbreaks, and most outbreaks (27/29, 93%) were caused by adenovirus. The findings regarding the difference in attack rate of adenovirus between males and females were not consistent. Poor maintenance and management of the pool (26/29, 90%), difficulty in early identification of outbreaks (21/29, 72%), and lack of public awareness of waterborne diseases (7/29, 24%) were the main causes of the outbreaks.ConclusionThis review reveals the causes of swimming pool-associated viral outbreaks in China, and possible preventive measures could include improving pool maintenance and management, early recognition of the outbreaks, and increasing public awareness of recreational water illnesses.
Supervision of students in a Portuguese veterinary medicine school—students’ and supervisors’ expectations, perceptions, and supervision impact
Authors: Cota João , Cunha Eva , Bexiga Ricardo , Oliveira Manuela 
Published: December 2024

IntroductionThe student-supervisor relationship can be a major cause of psychological distress experienced by students during their study programs. Misalignment between students’ and supervisors’ expectations and perceptions can originate conflicts, highly affecting the wellbeing of students and hindering the progress of their studies. This study was based on a questionnaire focusing on the perceptions of students and supervisors regarding the most important student attributes and outcomes, supervision expectations and perceptions, and supervision impact on mental health of students from a Portuguese Veterinary Medicine School.MethodsThe participants included 36 students from different study programs (bachelor’s, master’s, doctoral and veterinary specialization) and their corresponding supervisors (three).ResultsThe results indicate that veterinary post-graduate and specialization students and their supervisors share similar expectations regarding key student traits and supervision outcomes. Students expected supervisors to be actively involved, particularly in developing technical skills, and generally rated the supervision as of high or very high quality, emphasizing the importance of supervisors’ commitment. In contrast, supervisors were more focused on fostering students’ autonomy, and their assessments of the supervision quality were more diverse. The factors that most affected student’s mental health were the progress of the research or training program and students’ personal expectations, while supervisors perceived that their expectations also induced a negative impact on students’ mental health.DiscussionFurther and continuous research is needed to better understand both the needs and expectations of students and supervisors in different academic realities, including in Veterinary Medicine schools, from which the information available on the subject is scarce.
Trigonometric Polynomial Points in the Plane of a Triangle
Authors: Kimberling Clark , Moses Peter J. C. 
Published: December 2024

It is well known that the four ancient Greek triangle centers and others have homogeneous barycentric coordinates that are polynomials in the sidelengths a,b, and c of a triangle ABC. For example, the circumcenter is represented by the polynomial a(b2+c2−a2). It is not so well known that triangle centers have barycentric coordinates, such as tanA : tan B : tan C, that are also representable by polynomials, in this case, by p(a, b, c) : p(b, c, a) : p(c, a, b), where p(a, b, c)=a(a2+b2−c2)(a2+c2−b2). This paper presents and discusses the polynomial representations of triangle centers that have barycentric coordinates of the form f(a, b, c) : f(b, c, a) : f(c, a, b), where f depends on one or more of the functions in the set {cos, sin, tan, sec, csc, cot}. The topics discussed include infinite trigonometric orthopoints, the n-Euler line, and symbolic substitution.
Plant Growth-Promoting and Herbicidal Bacteria as Potential Bio-Based Solutions for Agriculture in Desertic Regions
Authors: Muñoz-Torres Patricio , Huanca-Mamani Wilson , Cárdenas-Ninasivincha Steffany , Aguilar Yola , Quezada Antonio , Bugueño Franco 
Published: December 2024

The region of Arica and Parinacota hosts unexplored remote sites with unique characteristics suitable for developing novel agricultural bioproducts. Notable locations include Jurasi Hot Springs, Polloquere Hot Springs, and Amuyo Lagoons, featuring open pools fed by thermal mountain springs. These geothermal sites harbor bacteria with plant growth-promoting activities, particularly interesting to the strains J19, TP22, A20, and A3. These bacteria possess in vitro plant growth-promoting traits, the ability to produce hydrolytic enzymes, and the capacity to inhibit phytopathogenic fungi. Moreover, they can tolerate different concentrations of NaCl and boron, making them suitable for developing new agricultural bioproducts for arid environments. The bacterial strains A3 and A20 have a positive effect on the growth of the aerial part of tomato plants (increased stem length, fresh and dry weight), with a significant increment in proline concentration and chlorophyll A and B content under saline conditions. Meanwhile, the strains J19 and TP22 exhibit herbicidal activity against Cenchrus echinatus by reducing root elongation and germination of the weed. These strains possess plant growth-promoting traits and improve plant resistance to salinity stress. They are promising candidates for developing innovative bio-based agricultural products suited to arid and semi-arid regions.
Implementation of a RESTful API-Based Evolutionary Algorithm in a Microservices Architecture for Course Timetabling
Authors: Zuhdi Ali Hisyam  , Ridho Farid , Setiyawan Arbi 
Published: December 2024

Introduction/Main Objectives: Implement an evolutionary algorithm within a RESTful API for a course timetabling system that employs a microservices architecture. Background Problems: The current course timetabling at Politeknik Statistika STIS uses the third-party application (aSc Timetables), which lacks a generator as a service, resulting in its inefficiency due to the lack of integration with SIPADU NG. Novelty: The evolutionary algorithm is built as a service (RESTful API) within a microservices architecture and supports custom constraints for timetables. Research Methods: One of the evolutionary algorithm families, the (1+1) evolutionary strategy, is implemented and used to create a course timetable 1000 times. Each course timetable created will have its cost calculated to assess the goodness of the algorithm implementation. The developed RESTful API is also evaluated through black box testing. Finding/Results: For the odd semester data, 40.5% of the trials yielded a cost value between 4 and 5, while for the even semester, all trials produced a cost value below 1. The resulting cost value is close to 0, which indicates that the timetable created has minimal violations. Additionally, black box testing concluded that the service operates as expected, delivering the anticipated output.
Remisión a largo plazo de un plasmacitoma óseo solitario con mínima afectación de la médula tratado solo con radioterapia: Reporte de caso
Authors: Martinez-Cordero Humberto , Seija Butnaru Daniela , Caro Perdomo Sandra 
Published: December 2024

El plasmacitoma óseo solitario y el plasmacitoma extramedular solitario son entidades raras, caracterizadas por la proliferación localizada de células plasmáticas monoclonales sin afectación sistémica. Hay un estadio intermedio entre el plasmacitoma solitario y el mieloma múltiple (MM) no secretor, conocido como plasmacitoma óseo solitario con mínima afectación de la médula ósea, que tiene un mayor riesgo de progresión a MM.
El porcentaje de infiltración de la médula ósea por células plasmáticas tumorales debe ser inferior al 10 % para que se considere un plasmacitoma óseo solitario con mínima afectación de la médula ósea y no un mieloma múltiple macrofocal no secretor. El presente caso, de un paciente masculino hispano de 42 años de edad, pone de manifiesto la difícil decisión de ofrecer solo una dosis alta de radioterapia frente a una terapia sistémica con trasplante autólogo de médula ósea, dada la infiltración límite del 10 % en la médula ósea. Finalmente, el paciente fue tratado solo con radioterapia, y permaneció libre de progresión tres años después del diagnóstico.
Лазерно-індуковані зміни оптичних властивостей аморфних плівок системи Ge-Se
Authors: Рубіш В. М. , Поп М. М. , Петров В. В. , Макар Л. І. , Крючин А. А. , Ясінко Т. І. , Рубіш В. В. , Микайло О. А. , Кайнц Д. І. , Костюкевич С. О. 
Published: December 2024

Досліджено вплив лазерного випромінювання з λ = 530 і 650 нм на спектри пропускання аморфних плівок GeSex. Розраховано значення ширини псевдо забороненої Eg та показника заломлення плівок. Виявлено два види фотоіндукованих ефектів у плівках — фотопросвітлення (GeSe5, GeSe3, GeSe2) і фотопотемніння (GeSe15). Встановлено, що рівень змін оптичних параметрів плівок GeSe5 і GeSe15 при їхньому лазерному опроміненні набагато вищий ніж плівок інших складів (GeSe8, GeSe4,GeSe3, GeSe2, Ge2Se3). Виявлено деякі відмінності в результатах досліджень плівок при їхньому опроміненні зеленим і червоним лазерами пов’язані з фотопластичним ефектом, який проявляється в них при за світці світлом з області краю власного поглинання.
Мережевий підхід при дослідженні каскадних ефектів критичних інфраструктур
Authors: Хоменко О. М. , Сенченко В. Р. , Коваль О. В. 
Published: December 2024

Каскадний збій у роботі критичної інфраструктури призводить до негативних наслідків, тому важливо вчасно виявити та провести превентивні дії для зменшення наслідків каскаду. У статті представлено аналіз можливостей мережевого підходу при побудові та дослідженні моделі каскаду на основі теорії графів. За допомогою метрик якості графів, можливо визначити центральність та важливість вузлів моделі, розрахувати імовірності переходів між вузлами, настання критичних подій, дослідити різні сценарії розвитку. Графічна модель енергомережі, являє взаємопов’язану мережу вузлів і кінцевих обмежень (лінія електропередачи, трансформаторна підстанція, імпеданс та інші). В статті розглянуто застосування різних мережевих підходів — мережі Баєса, Петрі, Маркова та наведено результати порівняльного аналізу їх можливостей при виникненні каскаду. Це дозволяє більш досконало адаптувати мережеві методи до конкретних потреб моделювання та сформувати вимоги до відповідних програмних засобів.