bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nitrogen form‐mediated ethylene signal regulates root‐to‐shoot K+ translocation via NRT1.5
Authors: Chen Haifei , Zhang Quan , Wang Xueru , Zhang Jianhua , Ismail Abdelbagi M. , Zhang Zhenhua 
Published: September 2021

AbstractNitrogen–potassium synergistic and antagonistic interactions are the typical case of nutrient interactions. However, the underlying mechanism for the integration of the external N form into K+ homeostasis remains unclear. Here, we show that opposite effects of NO3− and NH4+ on root‐shoot K+ translocation were due to differential regulation of an ethylene signalling pathway targeting the NRT1.5 transporter. NH4+ upregulated the transcriptional activity of EIN3, but repressed the expression of NRT1.5. However, the addition of NO3− strongly suppressed the activity of EIN3, whereas its addition upregulated the expression of AtNRT1.5 and shoot K+ concentration. The 35S:EIN3/ein3eil1 plants, nrt1.5 mutants and nrt1.5/skor double mutants displayed a low K+ chlorosis phenotype, especially under NH4+ conditions with low K+ supply. Ion content analyses indicate that root‐to‐shoot K+ translocation was significantly reduced in these mutants. A Y1H assay, an EMSA and a transient expression assay confirmed that AtEIN3 protein could directly bind to the promoter of NRT1.5 to repress its expression. Furthermore, grafted plants with the roots of 35S:EIN3 and ein3eil1/nrt1.5 mutants displayed marked leaf chlorosis with a low K+ concentration. Collectively, our findings reveal that the interaction between N form and K+ was achieved by modulating root‐derived ethylene signals to regulate root‐to‐shoot K+ translocation via NRT1.5.
Foliar respiration is related to photosynthetic, growth and carbohydrate response to experimental drought and elevated temperature
Authors: Collins Adam D. , Ryan Michael G. , Adams Henry D. , Dickman Lee Turin , Garcia‐Forner Núria , Grossiord Charlotte , Powers Heath H. , Sevanto Sanna , McDowell Nate G. 
Published: September 2021

AbstractShort‐term plant respiration (R) increases exponentially with rising temperature, but drought could reduce respiration by reducing growth and metabolism. Acclimation may alter these responses. We examined if species with different drought responses would differ in foliar R response to +4.8°C temperature and −45% precipitation in a field experiment with mature piñon and juniper trees, and if any differences between species were related to differences in photosynthesis rates, shoot growth and nonstructural carbohydrates (NSCs). Short‐term foliar R had a Q10 of 1.6 for piñon and 2.6 for juniper. Piñon foliar R did not respond to the +4.8°C temperatures, but R increased 1.4× for juniper. Across treatments, piñon foliage had higher growth, lower NSC content, 29% lower photosynthesis rates, and 44% lower R than juniper. Removing 45% precipitation had little impact on R for either species. Species differences in the response of R under elevated temperature were related to substrate availability and stomatal response to leaf water potential. Despite not acclimating to the higher temperature and having higher R than piñon, greater substrate availability in juniper suggests it could supply respiratory demand for much longer than piñon. Species responses will be critical in ecosystem response to a warmer climate.
Exploring stakeholders and their requirements in the process of home hemodialysis: A literature review
Authors: Khan Ilyas , Pintelon Liliane , Martin Harry , Khan Rahmat Ali 
Published: September 2021

AbstractProviding home hemodialysis (HHD) therapy is a complex process that not only requires the use of a complex technology but also involves a diverse group of stakeholders, and each stakeholder has their requirements and may not share a common interest. Bringing them together will require the alignment of their interests. A process management perspective can help to accomplish the alignment of their interests. To align their interests, it is crucial to identify interest groups and understand their interests. The main objective of this paper is to identify the stakeholders and represents their interests as a list of requirements in the HHD process. An extensive literature review has been carried out and PubMed was used for literature extraction. In total, 1848 articles were retrieved of which 80 have fulfilled the inclusion criteria. A large array of actors is identified and their interests/requirements at different stages of the HHD process are represented in the form of a list. They have both common and conflicting requirements in the HHD process. If these requirements are aligned and balanced, a stakeholder's driven treatment process will be developed and a real improvement will be achieved in the treatment process.
Informal social protection: A conceptual synthesis
Authors: Mumtaz Zahid 
Published: September 2021

AbstractVarious informal networks such as extended and immediate family, religious organizations, and NGOs assist a large segment of the neglected poor population worldwide by providing informal social protection. However, it is hard to locate a comprehensive definition of informal social protection that may help measure its aggregate benefits. Hence, it represents a considerable gap in the literature. To fill this gap, we used existing literature to define and devise a new framework to conceptualize and categorize informal social protection into three components: informal assistance, informal insurance, and informal labour market measures. By doing so, this paper makes critical contributions to the social policy literature as follows: First, the study synthesizes a sizeable body of research to provide a comprehensive definition and conceptualizes informal social protection in three components. The primary sources of the provision of three components of informal social protection are also presented. Second, this conceptualisation would help measure the concept of informal social protection and its attributes. Last, the proposed framework helps compare informal with formal social protection, which can further integrate the two forms of social protection. These contributions will respond to the repeated calls in the literature to advance the scholarship and develop meaningful questions for research on the role of informal social protection.
The political science of Covid‐19: An introduction
Authors: Barberia Lorena , Plümper Thomas , Whitten Guy D. 
Published: September 2021

AbstractPolitical decisions, constellations, and behaviors exert a large influence of the dynamics of the severe acute respiratory syndrome coronavirus 2 (Sars‐CoV‐2) pandemic. Politics influences the choice of containment policies and the compliance with these policies—and therefore ultimately the epidemiological situation in each country, state, district, or even neighborhood. This introduction puts the articles collected in this special issue into the broader perspective of the social science literature on Covid‐19.
Multicultural competencies training programs for health care staff and health students in academic and professional settings: a scoping review protocol
Authors: Teixeira-Santos Luísa , Camarneiro Ana Paula , Xavier Beatriz , Ventura Filipa , Cunha-Oliveira Aliete , Monteiro Ana Paula 
Published: September 2021

ABSTRACT

Objective:
The aim of the proposed scoping review is to identify training programs in multicultural competencies for health care staff and health students in professional and academic settings.

Introduction:
Cultural competence training for health care professionals is an imperative challenge in today's culturally diverse societies to ensure that all people receive equitable and effective health care, particularly those from culturally diverse backgrounds.

Inclusion criteria:
This scoping review will consider literature with adult participants aged ≥ 18 years, health care staff, and health students who may have received or are receiving multicultural competencies training. Literature published since 1960 in English, Portuguese, Spanish, and French will be considered for inclusion. Literature will be excluded if it reports on multicultural competencies training programs for students outside the health domain or for non-professional high school programs.

Methods:
The search strategy, designed according to the inclusion and exclusion criteria, will aim to find both published and unpublished literature. The following electronic databases will be searched: MEDLINE, CINAHL, Psychology and Behavioral Sciences Collection, Web of Science, Open Access Scientific Repository of Portugal (RCAAP), and Open Grey. Other sites to be searched include ClinicalTrials.gov; United Nations High Commissioner for Refugees (UNHCR); International Organization for Migration (IOM); and International Migration, Integration and Social Cohesion in Europe (IMISCOE). The screening process will consist of two steps carried out by two independent reviewers: firstly, screening by title and abstract; and secondly, by full text. Data will be charted to describe the body of literature according to the review research questions, which were defined following the Population, Concept, Context (PCC) mnemonic. Data will be presented graphically when possible, and accompanied by a narrative that describes the characteristics of the training programs.
Effect of very large body mass loss on energetics, mechanics and efficiency of walking in adults with obesity: mass‐driven versus behavioural adaptations
Authors: Malatesta Davide , Favre Julien , Ulrich Baptiste , Hans Didier , Suter Michel , Favre Lucie , Fernández Menéndez Aitor 
Published: September 2021

AbstractUnderstanding the mechanisms involved in the higher energy cost of walking (NCw: the energy expenditure above resting per unit distance) in adults with obesity is pivotal to optimizing the use of walking in weight management programmes. Therefore, this study aimed to investigate the mechanics, energetics and mechanical efficiency of walking after a large body mass loss induced by bariatric surgery in individuals with obesity. Nine adults (39.5 ± 8.6 year; BMI: 42.7 ± 4.6 kg m–2) walked at five fixed speeds before (baseline) and after the bariatric surgery (post 1 and post 2). Gas exchanges were measured to obtain NCw. A motion analysis system and instrumented treadmill were combined to assess total mechanical work (Wtot). Mechanical efficiency (Wtot NCw–1) was also calculated. Participants lost 25.7 ± 3.4% of their body mass at post 1 (6.6 months; P < 0.001) and 6.1 ± 4.9% more at post 2 (12 months; P = 0.014). Mass‐normalized NCw was similar between baseline and post 1 and decreased at post 2 compared to that at baseline (−6.2 ± 2.7%) and post 1 (−8.1 ± 1.9%; P ≤ 0.007). No difference was found in mass‐normalized Wtot during follow‐up (P = 0.36). Mechanical efficiency was similar at post 1 and post 2 when compared to that at baseline (P ≥ 0.19), but it was higher (+14.1 ± 4.6%) at post 2 than at post 1 (P = 0.013). These findings showed that after a very large body mass loss, individuals with obesity may reorganize their walking pattern into a gait more similar to that of lean adults, thus decreasing their NCw by making their muscles work more efficiently.
imageKey points
A higher net (above resting) energy cost of walking (lower gait economy) is observed in adults with obesity compared to lean individuals.
Understanding the mechanisms (i.e. mass driven, gait pattern and behavioural changes) involved in this extra cost of walking in adults with obesity is pivotal to optimizing the use of walking to promote daily physical activity and improve health in these individuals.
We found that very large weight loss induced by bariatric surgery significantly decreased the energy cost of walking per kg of body mass after 1 year with similar total mechanical work per kg of body mass, resulting in an increased mechanical efficiency of walking.
Individuals with obesity may reorganize their walking pattern into a gait more similar to that of adults of normal body mass, thus decreasing their energy cost of walking by making their muscles work more efficiently.
Computational Assessment of Hemodynamic Significance in Patients With Intramural Anomalous Aortic Origin of the Coronary Artery Using Virtually Derived Fractional Flow Reserve and Downstream Microvascular Resistance
Authors: Razavi Atefeh , Sachdeva Shagun , Frommelt Peter C. , LaDisa John F. 
Published: September 2021

Abstract
Anomalous aortic origin of a coronary artery (AAOCA) is the second most common cause of sudden cardiac death in young athletes. One of the hypothesized mechanisms of ischemia in these patients is the lateral compression of the anomalous artery with an intramural or interarterial course. The presence of a narrowing in the anomalous artery will cause physiologic changes in downstream resistance that should be included for computational assessment of possible clinical ramifications. In this study, we created different compression levels, i.e., proximal narrowing, in the intramural course of a representative patient model and calculated hyperemic stenosis resistance (HSR) as well as virtual fractional flow reserve (vFFR). Models also included the effect of the distal hyperemic microvascular resistance (HMR) on vFFR. Our results agreed with similar FFR studies indicating that FFR is increased with increasing HMR and that different compression levels could have similar FFR depending on the HMR. For example, vFFR at HSR: 1.0–1.3 and HMR: 2.30 mmHg/cm/s is 0.68 and close to vFFR at HSR: 0.6–0.7 and HMR: 1.6 mmHg/cm/s, which is 0.7. The current findings suggest that functional assessment of anomalous coronary arteries through FFR should consider the vascular resistance distal to the narrowing in addition to the impact of a proximal narrowing and provides computational approaches for implementation of these important considerations.
Material Identification on Thin Shells Using the Virtual Fields Method, Demonstrated on the Human Eardrum
Authors: Pires Felipe S. M. , Avril Stéphane , Livens Pieter , Cordioli Júlio A. , Dirckx Joris J. J. 
Published: September 2021

Abstract
Characterization of material parameters from experimental data remains challenging, especially on biological structures. One of such techniques allowing for the inverse determination of material parameters from measurement data is the virtual fields method (VFM). However, application of the VFM on general structures of complicated shape has not yet been extensively investigated. In this paper, we extend the framework of the VFM method to thin curved solids in three-dimensional, commonly denoted shells. Our method is then used to estimate the Young's modulus and hysteretic damping of the human eardrum. By utilizing Kirchhoff plate theory, we assume that the behavior of the shell varies linearly through the thickness. The total strain of the shell can then be separated in a bending and membrane strain. This in turn allowed for an application of the VFM based only on data of the outer surface of the shell. We validated our method on simulated and experimental data of a human eardrum made to vibrate at certain frequencies. It was shown that the identified material properties were accurately determined based only on data from the outer surface and are in agreement with literature. Additionally, we observed that neither the bending nor the membrane strain in an human eardrum can be neglected and both contribute significantly to the total strain found experimentally.
Binary Repetitive Model Predictive Active Flow Control Applied to an Annular Compressor Stator Cascade With Periodic Disturbances
Authors: Fietzke Benjamin , Mihalyovics Jan , King Rudibert , Peitsch Dieter 
Published: September 2021

Abstract
Novel pressure gain combustion concepts invoke periodic flow disturbances in a gas turbine's last compressor stator row. This contribution presents studies of mitigation efforts on the effects of these periodic disturbances on an annular compressor stator rig. The passages were equipped with pneumatic active flow control (AFC) influencing the stator blade's suction side, and a rotating throttling disk downstream of the passages inducing periodic disturbances. For steady blowing, it is shown that with increasing actuation amplitudes cμ, the extension of a hub corner vortex deteriorating the suction side flow can be reduced, resulting in an increased static pressure rise coefficient Cp of a passage. The effects of the induced periodic disturbances could not be addressed intrinsically, by using steady blowing actuation, Considering a corrected total pressure loss coefficient ζ*, which includes the actuation effort, the stator row's efficiency decreases with higher cμ due to the increasing costs of the actuation mass flow. Therefore, a closed-loop approach is presented to address the effects of the disturbances more specifically, thus lowering the actuation cost, i.e., mass flow. For this, a repetitive model predictive control (RMPC) was applied, taking advantage of the periodic nature of the induced disturbances. The presented RMPC formulation is restricted to a binary control domain to account for the used solenoid valves' switching character. An efficient implementation of the optimization within the RMPC is presented, which ensures real-time capability. As a result, Cp increases in a similar magnitude but with a lower actuation mass flow of up to 66%, resulting in a much lower ζ* for similar values of cμ.
An Investigation of the Tapered Strut on Aerodynamic Performance of the Exhaust Diffuser Under Different Swirls
Authors: Dong Yuxuan , Li Zhigang , Li Jun 
Published: September 2021

Abstract
The strut structure directly affects the flow-field characteristics and aerodynamic performance of the gas turbine exhaust diffuser. Based on verifying the reliability of the numerical method, the exhaust diffuser with different struts was numerically calculated by solving three-dimensional Reynolds-averaged Navier–Stokes. The flow process and flow loss mechanism in the diffuser were analyzed, the influence of two different structures of tapered struts on the aerodynamic performance of the exhaust diffuser under different inlet preswirls was explored, and the aerodynamic performance of the exhaust diffuser with tapered struts was compared with a conventional exhaust diffuser with linear struts. The results show that, compared with the conventional linear strut, under different inlet preswirls, two different tapered struts can both weaken the flow separation in the exhaust diffuser, thereby reducing the total pressure loss. When the inlet preswirl is greater than 0.35, the total pressure loss coefficient of the exhaust diffuser with structure-C tapered struts decreases by up to 0.07. The two types of tapered struts also change the flow structure at the exhaust diffuser outlet, which affects the uniformity of the outlet airflow, and then affect the static pressure recovery coefficient. Under different inlet preswirls, two types of tapered struts can be effective to increase the static pressure recovery coefficient of the exhaust diffuser, for the exhaust diffuser with structure-C tapered struts, the static pressure recovery coefficient can be increased by up to 0.065, relative increase of 20%. The research in this paper shows that the tapered structure can significantly improve the aerodynamic performance of the exhaust diffuser under different inlet preswirls.
Experimental Study of the Skin-Friction Topology Around the Ahmed Body in Cross-Wind Conditions
Authors: Tran The Hung , Anyoji Masayuki , Nakashima Takuji , Shimizu Keigo , Le Anh Dinh 
Published: September 2021

Abstract
In this study, skin friction around a ½-scale Ahmed body was measured experimentally at a Reynolds number of Re = 2 × 105. The slant angle of the Ahmed body was 25 deg, and the yaw angles ranged from 0 deg to 8 deg. This study focused on the flow structure on the slant surface under different cross-wind conditions. A force balance system was applied to measure the aerodynamic drag of the model. The global skin-friction topology was measured by applying a luminescent oil layer with a subgrid data processing algorithm. The method used to measure the skin friction was conducted for the first time on the Ahmed body. The results indicated that the technique is highly capable of extracting the skin-friction topology. For a yaw angle below 3 deg, the flow on the slant surface was not significantly affected by the cross-wind condition, and the drag of the model was nearly constant. However, at yaw angles above 3 deg, the flow on the slant surface was highly affected by the roof longitudinal vortexes on the windward side, leading to a dramatic increase in the drag of the model. High consistency in the drag and skin-friction fields was observed. The detailed skin-friction structure at different yaw angles will be discussed in this study.
Values and preferences towards medical cannabis among people living with chronic pain: a mixed-methods systematic review
Authors: Zeng Linan , Lytvyn Lyubov , Wang Xiaoqin , Kithulegoda Natasha , Agterberg Silvana , Shergill Yaad , Esfahani Meisam Abdar , Heen Anja Fog , Agoritsas Thomas , Guyatt Gordon H , Busse Jason W 
Published: September 2021

ObjectiveTo explore values and preferences towards medical cannabis among people living with chronic pain.DesignMixed-methods systematic review.Data sourcesWe searched MEDLINE, EMBASE and PsycINFO from inception to 17 March 2020.Study selectionPairs of reviewers independently screened search results and included quantitative, qualitative and mixed-methods studies reporting values and preferences towards medical cannabis among people living with chronic pain.Review methodsWe analysed data using meta-narrative synthesis (quantitative findings were qualitised) and tabulated review findings according to identified themes. We used the Grading of Recommendations Assessment, Development and Evaluation approach to assess certainty of evidence.ResultsOf 1838 initial records, 15 studies proved eligible for review. High to moderate certainty evidence showed that patient’s use of medical cannabis for chronic pain was influenced by both positive (eg, support from friends and family) and negative social factors (eg, stigma surrounding cannabis use). Most patients using medical cannabis favoured products with balanced ratios of tetrahydrocannabinol (THC) and cannabidiol (CBD), or high levels of CBD, but not high THC preparations. Many valued the effectiveness of medical cannabis for symptom management even when experiencing adverse events related to concentration, memory or fatigue. Reducing use of prescription medication was a motivating factor for use of medical cannabis, and concerns regarding addiction, losing control or acting strangely were disincentives. Out-of-pocket costs were a barrier, whereas legalisation of medical cannabis improved access and incentivised use.Low to very low certainty evidence suggested highly variable values towards medical cannabis among people living with chronic pain. Individuals with pain related to life-limiting disease were more willing to use medical cannabis, and preferred oral over inhaled administration.ConclusionsOur findings highlight factors that clinicians should consider when discussing medical cannabis. The variability of patients’ values and preferences emphasise the need for shared decision making when considering medical cannabis for chronic pain.
Pano pra manga
Authors: Vara Teresa Pires 
Published: September 2021

Originalmente publicado na revista Literatura e Sociedade, n. 2, p. 208-20, São Paulo, 1997. DOI:
https://doi.org/10.11606/issn.2237-1184.v0i2p208-220
O título “Pano pra manga” foi inspirado pelo prefácio de Alexandre de Eulálio ao livro de Gilda de Mello e Souza, O espírito das Roupas, a moda do século XIX; o capítulo pertence a um ensaio mais amplo, com o mesmo título, em que procuro trabalhar os limites da Crítica e da Criação.
Em tempo, gostaria de agradecer aos colegas responsáveis por este numero de Literatura e Sociedade, por terem concordado com minha proposta deste texto hibrido.