bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multidetector computed tomography for patients with congenital heart disease: a multi-center registry from Africa and Middle East; patients’ characteristics and procedural safety
Authors: Ezzeldin Dina Adel , Hafez Mohamed Saber , Mansour Amr 
Published: October 2021

Abstract
Background
We aimed to establish a clinical registry for patients with congenital heart disease who referred to multidetector computed tomography in our country, to describe the pattern and clinical profile of such patients and document the safety and efficacy of the procedure in our daily practice.

Results
A total 2310 studies were analyzed after excluding studies with missed, and lost data. Half of our study population—1215 patients—52.5% were males. The median age of the patients was 12 months (IQR 37 months), and the youngest patient was 3 days old. The eldest patient was 50 years old. 68.27% of the patients were less than 2 years old, and two-third of the whole studied population 66.7% had cyanotic heart disease. Minor local access complications, complications related to anesthetic drugs, and allergic reactions were the most commonly encountered complications, with only single mortality mainly due to multiple associated multisystem congenital malformation.

Conclusions
Most of our patients with congenital heart disease referred for MDCT study were infants and young children. The majority of them had complex cyanotic heart disease. The study is safe, with excellent diagnostic yield and safe with very low incidence of complications.
Sofosbuvir/ledipasvir safety and efficacy for HCV patients with haemodialysis and liver cirrhosis: a small retrospective study
Authors: Boushi Ebtisam , Cheha Khaled , Hedar Noha , Almokdad Rasha , Alassi Mohammed Waleed , Kakaje Ameer 
Published: October 2021

Abstract
Background
Hepatitis C virus (HCV) infection is a high prevalent disease. Sofosbuvir/ledipasvir (SOF/LDV) can successfully treat HCV and it was until recently that SOF/LDV was approved by the FDA in haemodialysis patients, but not in patients with liver cirrhosis. This study reports patients on haemodialysis and compensated liver cirrhosis who used this regiment. This is a retrospective study on patients who were on haemodialysis and used SOF/LDV for HCV treatment in one secondary health care facility (a hospital). Treatment consisted of 400g SOF and of 90g LDV once daily. Patients were assessed for HCV RNA at the end of treatment after 12 weeks and after 24 weeks for patients. New symptoms were also assessed.

Results
Our sample contained 16 males and 5 females with a mean age of 40.9 years. Nineteen patients had no cirrhosis of the liver, and the other two had clinical and radiological cirrhosis and had Child–Turcotte–Pugh (CTP) type B. Full follow-up was for only 20 patients and they all had HCV resolved as one patient had died from a stroke. Other factors were assessed such as HCV genotypes, but treatment had the same results with no difference in symptoms development (p>0.05). Twelve patients had HCV genotype 1, eight patients had HCV genotype 4, and one patient had HCV genotype 5.

Conclusion
Despite the small sample size, SOF/LDV combination is suggested to be effective in patients on haemodialysis and who had compensated cirrhosis and CTP type B without the need of dose adjustment or increase duration of treatment, and there were no major complications overall.
Gas chromatography–mass spectrometry (GC–MS) analysis of ethyl acetate root bark extract of Strychnos innocua (Delile)
Authors: Ibrahim Hamisu , Uttu Ahmed Jibrin , Sallau Muhammad Sani , Iyun Ogunkemi Risikat Agbeke 
Published: October 2021

Abstract
Background
Majority of phytochemicals have been known to bear valuable therapeutic activities such as insecticidal, antibacterial, antifungal, anticonstipative, spasmolytic, antiplasmodial and antioxidant activities. Strychnos innocua is straight-stemmed tree belonging to the family Loganiaceae and can grow up to 18 m tall. The plant is used for various pharmacological purposes. The aim of this study was to determine the chemical composition of the ethyl acetate extract of root bark of S. innocua using GC–MS analysis. The root bark was collected, air-dried and then crushed to powder. Standard extraction method (maceration) was used to obtain the ethyl acetate extract. The GC–MS was carried out on the extract using GC 7890B, MSD 5977A, Agilent Tech.

Results
Thirty-seven compounds were identified among which dibutyl benzene-1,2-dicarboxylate showed the highest peak area (31.03%) and monomethyl pimelate showed the lowest peak area (0.39%). The major compounds identified were cyclooctane (methoxymethoxy), 2,4-dimethylheptanedioic acid dimethyl ester, azelaic acid, 1,2-benzenedicarboxylic acid, bis(2-methylpropyl) ester, dibutyl benzene-1,2-dicarboxylate, butyl 8-methylnonyl benzene-1,2-dicarboxylate, 9,15-octadecadienoic acid, methyl ester, cis-vaccenic acid, linoleic acid ethyl ester and ethyl oleate.

Conclusions
In conclusion, these phytoconstituents might be responsible for the medicinal efficacy of the root bark of S. innocua and can be used as a source therapeutic drug.
Images of Tigers in Late Chosŏn Stories: In Relation to the Ecological Crisis of Chosŏn Tigers
Authors: Kim Youme , Kim Kyungmi 
Published: October 2021

Abstract
This study examines the images of tigers in late Chosŏn stories as they relate to ecological changes during the late Chosŏn period. As a popular literary topic, tigers have held various and sometimes conflicting roles, ranging from Heaven’s sacred agents to brutal beasts. The increase in human population and the expansion of farmland caused the loss of tigers’ habitats and narrowed their food sources, which eventually increased tiger-human encounters and intensified state-led tiger extermination policies. This study shows that the images of tigers generally shifted from formidable and mysterious beings to controllable, wounded, and even obedient animals over time. The frequent descriptions of tigers killed by women, tigers asking for people’s help, and porridge-eating tigers in late Chosŏn stories reflect people’s modified view of tigers, even though actual tigers remained a threat during that period. A consideration of the ecological factors depicted in tiger stories over time suggests that changes in the societal point of view regarding these animals impact how tigers’ characters were portrayed.
Ambiguous Founding Father: Tan’gun as a Korean-Japanese God
Authors: Kim Nuri 
Published: October 2021

Abstract
Although Tan’gun, Korea’s mythical founding father, is often depicted as an undisputed symbol of Korean nationalism, this article sheds light on a more complex history in which Tan’gun stands at the center of contesting forces and ambiguous understandings. In fact, besides his nationalist deployment, he was also mobilized as a symbol of Korean-Japanese affinity, which, in turn, was based on centuries of Japanese engagements with the mythical progenitor. As a more cosmopolitan conceptualization of Tan’gun obtained imperialist dimensions in the early twentieth century, it also interacted with and stimulated Korean nationalist utilizations of the founding father. By investigating Tan’gun’s “other” history, this article complicates our understanding of how the figure of Tan’gun evolved into the prime symbol of Korean nationalism and how Koreans negotiated their historical identity within the Japanese empire.
A ciberpublicidade presente na promoção da transparência na indústria da moda: uma análise da campanha #quemfezminhasroupas no Instagram
Authors: Danni Danielle Correia. N. Abreu , De Sousa Lacerda Juciano 
Published: October 2021

Este artigo tem como objetivo investigar como marcas brasileiras ligadas ao universo da moda integraram a campanha, coordenada pelo movimento Fashion Revolution, #quemfezminhasroupas no Instagram. Para isso, foi feito um mapeamento da respectiva hashtag, durante o mês de abril de 2019 na rede social digital Instagram. Desse modo, através dessas postagens, foi possível refletir um pouco a respeito dos bastidores da cadeia produtiva da moda nacional. Nesse sentido, foi possível vislumbrar a partir das publicações encontradas, como as marcas cumpriram os objetivos da campanha #quemfezminhasroupas. Assim, foram encontradas 297 postagens que somaram 650 imagens, as quais foram submetidas à análises quantitativas e qualitativas. Portanto, após uma análise de conteúdo (Bardin, 2016) da respectiva hashtag, os resultados indicaram que as marcas estavam mais envolvidas em promover a interatividade, a relevância e a experiência (Atem et al., 2014) em detrimento dos principais objetivos da campanha #quemfezminhasroupas impulsionada pelo Fashion Revolution Brasil.
Una geografía de México en Netflix: recomendaciones automatizadas y diversidad de contenidos ofertados
Authors: SUED GABRIELA ELISA 
Published: October 2021

Se presenta un estudio centrado en información brindada por usuarios sobre las lógicas automatizadas de recomendación de contenidos asociados a México en Netflix. Se propone determinar si estos contribuyen a la diversidad audiovisual, así como identificar los parámetros de la plataforma para efectuar recomendaciones. Mediante un instrumento basado en técnicas de auditoría algorítmica, se comprueba que las fuentes que se priorizan son de origen norteamericano, que los contenidos son poco diversos y se orientan según el género —femenino o masculino— de los usuarios, que la personalización es baja y que la audiencia presenta una alta aceptación a las recomendaciones, excepto en tematizaciones del narcotráfico y estereotipos de género.
Factores de riesgo biomecánico lumbar por manejo manual de cargas en el reparto de productos cárnicos
Authors: Ibarra Villanueva Carlos , Astudillo-Cornejo Pamela 
Published: October 2021

Introducción: Identificar los factores de riesgo de trastornos musculoesqueléticos (TME) lumbares asociados al manejo manual (MMC) de productos cárnicos en las actividades de carga y descarga de camiones.
Método: Estudio observacional descriptivo transversal con enfoque mixto, basado en el análisis ergonómico de la actividad de trabajo. Participaron los 4 trabajadores de los puestos de cargador y cargador-conductor. Se realizaron análisis cinemáticos y dinamométricos para determinar las fuerzas de compresión y cizallamiento y el riesgo biomecánico musculoesquelético en la zona lumbar. Se realizaron entrevistas y observaciones para analizar tareas y determinar los tiempos involucrados en cada operación, tipo de exposición y los determinantes de la actividad de trabajo.
Resultados: El contexto de trabajo es sumamente variable durante la carga y descarga del camión, considerando la variabilidad en cada punto de entrega las características de los estacionamientos, las condiciones climáticas, la presencia de animales y otros obstáculos durante el transporte manual de la carga. El MMC produce fuerzas sobre los 4000 N de compresión discal en los niveles L4-L5 y L5-S1, las fuerzas iniciales de empuje y arrastre fueron de 51.2 kg*f y 27.3 kg*f respectivamente, lo que evidencia el riesgo de TME. La actividad de trabajo está determinada por el tipo de jornada, la organización del reparto y la falta de medios mecánicos de apoyo para la carga y descarga de los camiones.
Conclusiones: Las tareas de MMC en esta industria son físicamente muy exigentes y mejorar estas condiciones de trabajo representa un desafío importante para la prevención.
Factores de Riesgo de Contagio de la Covid-19 en Personal Sanitario
Authors: Ciorba Ciorba Florin , Flores Benítez Javier , Hernandez Iglesias Raul , Inglés Torruella Joan , Olona Cabases Mª Montserrat 
Published: October 2021

Objetivos: El personal sanitario se sitúa en la primera barrera en la lucha contra la Covid-19, constituyendo un colectivo con una alto riesgo de infección. El objetivo del presente estudio es describir los factores de riesgo asociados en una población de profesionales que trabajan en un consorcio sanitario que incluye diferentes centros relacionados con la atención a la salud.
Métodos: Estudio observacional analítico retrospectivo; población 2.620 trabajadores sanitarios; desde el inicio del Estado de Alarma en España (15/03/20) hasta 21/06/2020. Se calcula la asociación entre las variables independientes sexo, edad, años de antigüedad, categoría profesional y lugar de trabajo con la presencia de Covid-19 mediante la prueba Chi-Cuadrado y el cálculo de la Odds Ratio (OR) e intervalo de confianza al 95% (IC95%) simple y ajustado mediante Regresión Logística Múltiple. Límite de significación aceptado ≤0,05.
Resultados: El personal sanitario, en todas las categorías, presenta siempre más riesgo respecto al no sanitario. Enfermería mostró los riesgos más altos -OR:14,03 (3,19-61,66)-. En el lugar de trabajo, Hospitalización-Médico-Quirúrgica -OR:13,43 (1,7-106,12)- y Sociosanitario -OR:17,77 (2,19-144,04)- presentaron más riesgo respecto a los que no tienen contacto con pacientes.
Conclusión: El riesgo más elevado de contagio se presentó entre los profesionales que tienen mayor contacto con pacientes y en los lugares en los que se detectaron por PCR positivos para Covid-19 entre los pacientes ingresados por otras patologías, teniendo un riesgo mayor los profesionales que atienden estos pacientes que aquellos que atienden zonas destinadas a Covid-19.
Respuesta vacunal frente a SARS-CoV-2 en trabajadores de un hospital
Authors: Sabater Vidal Susana , Bellido-Cambrón Mª Carmen , Arnedo-Pena Alberto , Palomares-Gallego Mª Isabel , Larrea-González Rosa María , Carballido-Fernández Mario , Moreno-Muñoz Rosario 
Published: October 2021

Introducción: Evaluar la inmunidad de los trabajadores de un hospital tras haber completado la vacunación Pfizer-BionTech, y su relación con factores individuales. También describir los efectos adversos de la vacuna.
Método: Estudio transversal de una muestra de los trabajadores del Hospital General Universitario de Castellón vacunados con dos dosis en enero y febrero de 2021. Un mes después se detectaron: anticuerpos IgG frente a la proteína N (IgG-NP), de IgM frente a la proteína S (IgM-S) y detección cuantitativa de IgG frente a la proteína S (IgG-Quant). Se utilizó un cuestionario para recoger datos demográficos, factores de riesgo y efectos secundarios. En el análisis estadístico se utilizaron modelos de regresión múltiple.
Resultados: La participación fue del 96,8% (275/284). Presentaron IgG-Quant el 99,6%, 14,9% IgM-S, y 4,4% IgG-NP. El nivel ajustado de IgG-Quant aumentó significativamente con la obesidad, en no fumadores y con positividad IgM-S y/o IgG-NP. La prevalencia de IgM-S era mayor en varones, y se asociaba con los mismos factores que la IgG-Quant. De los infectados por COVID-19, el 42,9% no presentaron IgG-NP. Un 86,5% sufrió algún efecto secundario que se asoció a tener IgG-NP, mayores niveles de IgG-Quant, y fue más frecuente en jóvenes y mujeres.
Conclusiones: Todos los participantes desarrollaron inmunidad humoral excepto uno. Tuvieron mayores niveles de anticuerpos los que habían padecido la COVID-19. Un porcentaje alto desarrolló efectos secundarios leves, más frecuentes en los que habían padecido la enfermedad.
Non-invasive vagus nerve stimulation for treatment of cluster headache: a retrospective review of prescribing in England
Authors: Silver Nicholas , Bradley Carl , Stuckey Rebecca , Murphy Madeleine , Greenwood Fiona , Abdallah Angela , Weatherby Stuart , Lambru Giorgio , Ahmed Fayyaz , Liebler Eric , Edey Paul , Strickland Iain , Goadsby Peter 
Published: October 2021

Background/Aims Beginning in April 2019, non-invasive vagus nerve stimulation was included in the NHS Innovation and Technology Payment programme. The programme guaranteed reimbursement of at least a 3-month course of treatment using gammaCore, through a prescription refill card, authorised by a headache specialist for patients with cluster headache who reported a clinically meaningful benefit. This study evaluated prescribing and refill trends to assess the use of gammaCore in England since the beginning of this programme. Methods Data regarding gammaCore prescriptions and refills from 1 April 2019 to 31 December 2020 were collected and tabulated. Patients were categorised into three groups: those who initiated gammaCore therapy under the programme (new starters), those who were prescribed ≥1 refill, and those who were prescribed ≥2 refills. One refill corresponds to 3 months of gammaCore therapy. Results In total, 52 NHS sites submitted 2092 prescriptions for gammaCore devices, including 655 for new starters. Among new starters, 46.3% received ≥1 refill and 30.9% received ≥2 refills. Those who started using gammaCore after its inclusion in the Innovation and Technology Payment programme received up to seven refills during the data collection period, representing 21 months of therapy. Conclusions This is one of the largest clinical audits of patients with cluster headache. Patients' continued use of gammaCore treatment through multiple 3-month refills in this audit suggests that non-invasive vagus nerve stimulation is efficacious, tolerable and practical for patients with cluster headache.
2-Verma modules
Authors: Naisse Grégoire , Vaz Pedro 
Published: October 2021

Abstract
We construct a categorification of parabolic Verma modules for symmetrizable Kac–Moody algebras using KLR-like diagrammatic algebras.
We show that our construction arises naturally from a dg-enhancement of the cyclotomic quotients of the KLR-algebras.
As a consequence, we are able to recover the usual categorification of integrable modules.
We also introduce a notion of dg-2-representation for quantum Kac–Moody algebras, and in particular of parabolic 2-Verma modules.
VI-modules in non-describing characteristic, part II
Authors: Nagpal Rohit 
Published: October 2021

Abstract
We classify all irreducible generic

VI

{\mathrm{VI}}

-modules in non-describing characteristic.
Our result degenerates to yield a classification of irreducible generic

FI

{\mathrm{FI}}

-modules in arbitrary characteristic. Equivalently, we provide a complete classification of irreducibles of admissible

𝐆𝐋
∞

⁢

(

𝔽
q

)

{\mathbf{GL}_{\infty}(\mathbb{F}_{q})}

-representations in non-describing characteristic, which is new even in characteristic zero. This result degenerates to provide a complete classification of irreducibles of admissible

S
∞

{S_{\infty}}

-representations in arbitrary characteristic, which is new away from characteristic zero.
Unveiling and packaging: A model for presenting philosophy in schools
Authors: Sowey Michelle 
Published: October 2021

Abstract
As a philosopher and a reflective practitioner of philosophy in schools, I explore two aspects of presentation which I call unveiling and packaging. Both aspects bear on the work of designing and facilitating philosophy workshops for school students. I describe unveiling philosophy as a practice of collaborative inquiry and dialogic argument: social processes that foster thinking skills and dispositions, an evaluativist epistemology, and a range of constructive norms. I then discuss packaging philosophical materials in ways that create effective stimuli for thinking. I encourage educators engaged in designing or curating stimuli to draw on the rich diversity of available media, to focus on the quality of both the philosophical content and its creative expression, and to ensure that the content connects with students’ life experiences. I propose five criteria for judging the likely effectiveness of a philosophical stimulus: that it activate emotion, induce perplexity, challenge intuitions, ignite controversy and elicit reasoned argument. I offer three detailed examples of high school philosophy workshops to illustrate the practical application of these criteria, and to illuminate fruitful possibilities for arranging stimuli, including using a Provocation-Complication sequence or arranging stimuli as elements in a more complex puzzle.
The soul of philosophy in a soulless age
Authors: Skrbina David 
Published: October 2021

Abstract
In its original Greek conception, philosophy was intended to promote both wisdom and virtue among society; in this sense, the teaching, or presenting, of philosophy is central to its essence. Socrates and Plato famously grappled with the question of how to impart wisdom and virtue to the learner, with mixed results. One of the standard methods—reading and writing—was argued to be misleading and even deceptive, because it deals with static, ‘dead’ words and ideas rather than with the “living discourse” of one person speaking directly to another. This general critique of certain ‘technologies’ of learning is even more relevant today, in our technological age, where the presenting of philosophy often involves computers, laptops, and the Internet. Such things come to function as addictive drugs—much like the pharmakon that Plato warned of. Philosophy would thus be better served by less use of mediating technologies and by a return to live, interactive, living dialogue between student and teacher.
Ways of life as modes of presentation
Authors: Hollinshead Brylea , Turp Michael-John 
Published: October 2021

Abstract
Books and journal articles have become the dominant modes of presentation in contemporary philosophy. This historically contingent paradigm prioritises textual expression and assumes a distinction between philosophical practice and its presented product. Using Socrates and Diogenes as exemplars, we challenge the presumed supremacy of the text and defend the importance of ways of life as modes of practiced presentation. We argue that text cannot capture the embodied activity of philosophy without remainder, and is therefore limited and incomplete. In particular, we contend that (1) a static text is essentially alienated from our practices of philosophising, (2) words cannot unambiguously represent lives, and (3) practiced presentation enriches our understanding beyond words alone. After discussing some pedagogical implications, we conclude with a plea for a pluralistic approach that recognises lives as legitimate and valuable modes of philosophical presentation.
Presenting philosophy – What science has taught me about it
Authors: Pigliucci Massimo 
Published: October 2021

Abstract
Presenting philosophy properly, in a way that is clear and accessible to our target audience, is of paramount importance. In this essay I draw on my dual experience as a scientist and a philosopher (as well as science and philosophy communicator) to arrive at some general recommendations for good practice. Specifically, I discuss why presentation matters, whether a bad presentation style is a valid criticism of a philosopher’s work, how we may adapt our message to the variety of communication media available today, and what, if any, is the relationship between how we present and how we conceive of philosophy itself.
Making philosophical thought dangerous again: Heidegger’s attack on journalistic writing
Authors: Weidler Markus 
Published: October 2021

Abstract
When it comes to questions about alternative visions for philosophical engagement, Heidegger’s work makes for an interesting case study, especially if we focus on his texts from the turbulent 1930s. As a shortcut into this contested territory, it is instructive to examine Heidegger’s anti-journalistic gestures, centered on the question whether this animosity is bound to drive a wedge between, or rather prompt a re-approximation of, philosophy and public scholarship. To render this programmatic concern more specific, the present essay aims to reassess Heidegger’s profile by considering his account of language as the “most dangerous of goods” bestowed on humans. This theme can serve as an expedient starting point for scrutinizing philosophers’ self-understanding as daring explorers in pursuit of profound insights into the human condition, and their (in)ability to balance excitement and sobriety.