bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efektivitas Bawang Hitam terhadap Penyembuhan Luka pada Kelinci
Authors: Putra Teguh Adiyas , Ulfah Mariam , Nesta Nesta 
Published: December 2024

Pendahuluan: Kulit manusia dalam melakukan aktifitas sehari-hari tidak dapat terhindar dari yang namanya luka. Luka sayat merupakan jenis luka akut dan luka terbuka yang disebabkan adanya kontak antara tubuh dengan benda-benda tajam. Bawang hitam diketahui memiliki kandungan empat sampai delapan kali lipat dibandingkan dengan bawang putih segar termasuk peningkatan kadar senyawa polifenol dan senyawa flavonoid yang bermanfaat dalam mempercepat penyembuhan luka serta anti-inflamasi. Tujuan: Penelitian ini adalah untuk mengetahui efektivitas dan konsentrasi yang optimal bawang hitam terhadap penyembuhan luka sayat. Metode: Penelitian ini merupakan penelitian eksperimental dengan melihat pengaruh ekstrak bawang hitam terhadap luka sayat pada kelinci dengan konsentrasi ekstrak sebesar 20%, 30%, dan 40% menggunakan 3 ekor kelinci yang masing-masing memiliki 5 luka sayat. Hasil: penelitian menunjukan adanya senyawa metabolit sekunder berupa flavonoid, polifenol, saponin, dan alkaloid. Uji penyembuhan luka pada konsentasi 20% menunjukan dengan rata-rata lama sembuh selama 7 hari, konsentrasi 30% menunjukan dengan rata-rata lama sembuh selama 7 hari, dan 40% menunjukan dengan rata-rata lama sembuh selama 6 hari Kesimpulan: Dapat disimpulkan bahwa konsentrasi yang paling baik terhadap penyembuhan luka sayat pada kelinci adalah pada konsentrasi 40% dengan waktu penyembuhan rata-rata selama 6 hari.Kata Kunci: Bawang Hitam, Luka Sayat, Kelinci
KARAKTERISTIK FISIKO-KIMIA TEPUNG PRA-TREATMENT PISANG TANDUK UNTUK PENDERITA DIABETES MELITUS TIPE 2
Authors: Palupi Fitria Dhenok , Hapsari Indri , Hasan Wattiheluw Muhammad 
Published: December 2024

A

ABSTRAK

Penderita diabetes melitus tipe 2 terus meningkat setiap tahun, salah satunya disebabkan oleh perubahan pola makan yang memengaruhi mikrobiota usus. Kontrol glikemik menjadi tujuan utama dalam penanganan diabetes, salah satunya melalui konsumsi serat makanan seperti pati resisten yang berfungsi sebagai prebiotik. Pisang tanduk merupakan sumber pati resisten, dan kandungannya dapat ditingkatkan melalui modifikasi seperti pra-treatmen pemanasan dan pendinginan cepat. Penelitian ini bertujuan untuk menganalisis pengaruh kombinasi pra-treatmen, seperti perebusan, pengukusan, serta penyimpanan di suhu rendah (refrigerator dan freezer), terhadap mutu fisiko-kimia tepung pisang tanduk varietas lokal Indonesia.Penelitian ini melibatkan 11 perlakuan dengan 3 kali replikasi, total 33 sampel. Parameter yang dinilai meliputi sifat organoleptik, mutu fisik (densitas kamba dan rendemen), serta mutu kimia (kadar pati dan pati resisten). Hasil menunjukkan pra-treatmen memengaruhi warna dan tekstur tepung, di mana kukus + freezer memengaruhi tekstur. Perlakuan ini berpengaruh signifikan terhadap mutu fisik dan kadar pati resisten, tetapi tidak terhadap kadar pati. Rendemen tertinggi ditemukan pada perlakuan rebus + freezer 24 dan 48 jam, sedangkan densitas kamba tertinggi pada rebus, kukus, dan penyimpanan refrigerator. Pati resisten meningkat pada kukus + freezer 48 jam dan rebus + freezer 24 jam. Kesimpulannya, perlakuan terbaik adalah perebusan disimpan di freezer 24 jam dan pengukusan disimpan di freezer 48 jam.

Kata kunci: Diabetes Melitus; Pisang Tanduk; Pra-treatment
PENGARUH MODEL PROBLEM BASED LEARNING (PBL) TERHADAP HASIL BELAJAR DAN MOTIVASI SISWA KELAS X MAS AL- MUNAWWARAH LOLEOJAYA PADA MATERI IKATAN KIMIA
Authors: Ajudin Nurbani , Sugrah Nurfatimah , Jayali Ahmad Muchin , Mustafa Linda Kurnia , Rakhman Khusna Arif 
Published: December 2024

AbstrakPenelitian ini dilakukan dengan tujuan untuk pengaruh model problem based learnig terhadap hasil belajar dan motivasi siswa kelas X Mas Al-munawwarah pada materi ikatan kimia. Jenis penelitian ini adalah penelitian eksperimen dengan desain penelitian yaitu per eksperimental one gorup pritest-postest ,lembaran angket dan respon siswa dengan jumlah sampel yang digunakan 16 siswa. Berdasarkan analisis data, dapat disimpulkan bahwa pengaru model PBL terhadapa hasil belajar dan motivasi siswa dapat meningkatkan hasil belajar siswa dengan interpretasi normal. Hal ini sesuai dengan hasil uji hipotesis menggunakan SPSS 21,0 dengan uji pired sample t test. Dapat disimpulkan bahwa pengaru model PBL terhadap hasil belajar dan motivasi siswa dapat meningkatkan hasil belajar dan motivasi tetapi tidak ada hubungan hasil belajar dan motivasi. diperoleh nilai sign sebesar 0,001 (P) 0,05 maka Ho ditolak dan Ha diterima. diperoleh mean rank atau rata-rata penigkatannya sebesar 20,06 dengan interpretasi rendah. AbstractStudi This was done with the aim of determining the influence of the problem based learnig model on the learnig outcomes and motivation of class X Mas AL-Munawwarah students on chemical boding material. This type of research is experimental research with a research desing, namely per experimental one group test-posttest, questionnaire sheets and student responses. with a total sample of 16 students. Based on data analysis, it can be concluded that the influence of the PBL model on student learning outcomes and motivation can improve student learning outcomes with normal interpretation. This is in accordance with the results of hypothesis testing using SPSS 21.0 with the Experimental One Groups test. It can be concluded that the influence of the PBL model on student learning outcomes and motivation can improve learning outcomes and motivation but there is no relationship between learning outcomes and motivation. obtained a sign value of 0.001 (P) 0.05, then Ho is rejected and Ha is accepted. The mean rank or average increase was 20.06 with a low interpretation.
Desain Dan Uji Coba Media Pembelajaran Vir-Lab Pada Materi Asam Basa
Authors: Taher Sarmilah A , Amin Muhammad , Ibrahim Fitriana , Limatahu Nur Asbirayani , Sriwahyuni Elsa 
Published: December 2024

AbstrakPenelitian ini bertujuan untuk mengetahui tingkat validitas media vir-lab pada konsep asam basa dan mengetahui tingkat kepraktisan media vir-lab pada konsep asam basa. Jenis penelitian ini adalah pengembangan RD dengan model ADDIE Analisis, Desain, Pengembangan, Implementasi, Evaluasi. Subjek dalam penelitian ini adalah ahli media, ahli materi, guru dan siswa kelas XI MA Babang. Objek penelitian ini adalah media pembelajaran vir-lab. Teknik pengumpulan data dari angket uji validitas, uji praktikalitas dan uji respon siswa. Penelitian menghasilkan produk berupa media pembelajaran vir-lab yang layak untuk digunakan. Hasil penelitian menunjukkan tingkat validitas media oleh 2 orang ahli media masing-masing sebesar 92% (sangat valid), 96% (sangat valid), ahli materi 95% (sangat valid), tingkat praktikalitas oleh G1 97,7% (sangat praktis), G2 95,5% (sangat praktis), G3 93,5% (sangat praktis), G4 91,1% (sangat praktis), G5 97,7% (sangat praktis) dan uji respon siswa 94,24% bahwa media vir-lab berbasis aplikasi sangat praktis digunakan dalam pembelajaran. Kata Kunci: Media, Vir-Lab, Asam BasaAbstractThis research aims to determine the level of validity of vir-lab media on the acid-base concept and determine the level of practicality of vir-lab media on the acid-base concept. This type of research is RD development with ADDIE Analysis, Design, Development, Implementation, Evaluation models. The subjects in this study are media experts, material experts, teachers and students of grade XI MA Babang. The object of this research is a vir-lab learning medium. Data collection techniques from validity test questionnaires, practicality tests and student response tests. Research produces products in the form of vir-lab learning media that are suitable for use. The results showed the media validity rate by 2 media experts each at 92% (very valid), 96% (very valid), material expert 95% (very valid), the level of practicality by G1 97.7% (very practical), G2 95.5% (very practical), G3 93.5% (very practical), G4 91.1% (very practical), G5 97.7% (very practical) and student response test 94.24% that application-based vir-lab media is very practical used in learning.Keywords:Media, Vir-Lab, Acid Base
THE EFFECT OF PROBLEM BASED LEARNING WITH TEAM ASSISTED INDIVIDUALIZATION, PROBLEM BASED LEARNING WITH THINK PAIR SHARE, AND COGNITIVE MODELS ON LEARNING OUTCOMES
Authors: Wasilah Umi , Rufi’i Rufi’i , Suhari Suhari 
Published: December 2024

This study was to determine the effect of a combination of problem-based learning with team-assisted individualization, problem-based learning with think pair share, and cognitive style on learning outcomes. This type of research is a quasi-experimental design that uses a 2x2 factorial design. The research population was XI Mathematics and Natural Science (MIPA) students in SMAN 1 Kraksaan and XI Mathematics and Natural Science (MIPA) of SMAN 1 Paiton Probolinggo, East Java, Indonesia, in 2022/2023. the samples were selected non-randomly, consisting of problem-based learning with team-assisted individualization (control) and PBL-TPS (experimental) groups. In both groups, given cognitive style test. The research instrument was 25 multiple-choice questions. Instrument validation is valid (0.89) and reliable (0.94). Posttest results were analyzed by two-way ANOVA test through SPSS v. 25. The study's results were; 1) There are differences in learning outcomes between problem-based learning with team-assisted individualization groups and problem-based learning with think pair share; 2) There are differences in learning outcomes between groups of cognitive style Field Dependent with cognitive style Field Independent; and 3) There is no interaction between learning models and cognitive styles on learning outcomes.
The Armoured Self, Un-becoming the Subject: Reading Julia Ducournau’s Titane (2021) Via Wyndham Lewis and Vorticism
Authors: Eden Michael 
Published: December 2024

In this paper, I explore what Lisa Tickner calls a ‘dissentient position’ in Modernism that assumes dehumanisation as a value of a new and brutal subjectivity and places the machine as a totemic deity. My understanding of this draws from the aesthetic language of Vorticism, particularly representations of women in the work of Wyndham Lewis. Moreover, I argue that this ‘machinic-modernism’ as Hal Foster describes it, which emerged in the early 20th century as a reaction to industrialised modernity, corporatisation, Taylorism, and Fordism, has a powerful and unacknowledged inheritor in the contemporary Palme d'Or winning film Titane (2021) written and directed by the auteur Julia Ducournau. I argue that the figure of Alexia in Titane, portrayed by actress and model Agathe Rousselle, is a celebration of dehumanisation that follows an anti-humanist path – sexually-combative femininity purged to become a hyper-masculine recruit, emerging as a biomechanical self – I claim that, while the modernism of Lewis and the creative intentions of Ducournau may have stemmed from different motivations, their utmost horizon for the subject and society is the same one, the swapping out of the tension of masculine and feminine for a machinic-self defined by ferocity, abjection, and trauma. I will also refer to the text Filibusters in Barbary from 1932 which is a reflective account of travels in North Africa including revealing attitudes of Lewis’s regarding machines which are, in common with the themes of Titane, anthropomorphised and presented as magical, violent, more frightening than monsters, and as having replaced gods. Ducournau and Lewis are reactive to the same social forces and rebarbative to so-called bourgeois conceptions of femininity in favour of a subjectivity that exists in a highly stratified social organisation.
PENGARUH KONSENTRASI TERPENTIN PADA PROSES PEMURNIAN GETAH PINUS (P. merkusii) TERHADAP KUALITAS GUM ROSIN
Authors: Wahyuningsih Waqida Aprillia Sri , Dewajani Heny , Prasetya Desta Enggar Dwi 
Published: December 2024

Gum rosin merupakan hasil distilasi getah pinus yang terdiri dari asam rosin. Semakin baik kualitas gum rosin maka harganya akan semakin tinggi. Kualitas gum rosin yang dihasilkan PT Inhutani V masih memiliki tipe Water White (WW) sehingga perlu adanya perbaikan proses produksi agar kualitas dan harga gum rosin dapat meningkat. Penelitian ini bertujuan untuk mengetahui pengaruh konsentrasi terpentin pada proses pemurnian getah pinus terhadap kualitas gum rosin. Proses pembuatan gum rosin melalui dua tahapan, yaitu pemurnian getah dan distilasi. Tahap pemurnian getah menggunakan pelarut terpentin bertujuan untuk menghasilkan larutan getah murni yang disebut Oleo Pine Resin (OPR). Tahap ini dilakukan dengan pemanasan pada suhu 85 oC disertai pengadukan dengan variabel konsentrasi terpentin 28,5%; 30,5%; dan 32,5% dari getah. Kemudian dilanjutkan dengan tahap distilasi pada suhu 175 oC selama 3 jam untuk menghasilkan gum rosin. Gum rosin hasil proses distilasi diuji warna, bilangan asam, titik lunak, dan komponen tidak menguapnya kemudian dibandingan dengan SNI 7636:2020. Dari hasil penelitian, dapat diketahui bahwa semakin tinggi konsentrasi terpentin maka bilangan asam, titik lunak, dan komponen tidak menguap gum rosin semakin menurun. Hasil gum rosin terbaik yang memenuhi standar SNI 7636:2020 diperoleh pada penambahan terpentin 28,5% dengan warna 6,9, bilangan asam 193,19 mg KOH/g, titik lunak 81,5 oC, dan komponen tidak menguap 98,22%.
PENGARUH PENAMBAHAN NATRIUM METABISULFIT PADA REAKSI BROWNING TERHADAP KUALITAS GUM ROSIN DI PT INHUTANI V TRENGGALEK
Authors: Maiyansari Yanti Noer , Prayitno  , Prasetya Desta Enggar Dwi 
Published: December 2024

Gum rosin merupakan hasil proses distilasi dari pengolahan getah pohon pinus PT Inhutani V. Gum rosin digunakan sebagai perekat, cat pelitur, dan tinta cetak. Parameter utama kualitas gum rosin ialah warna, dimana warna memiliki grade diantaranya extra white (X), water white (WW), window glass (WG), dan nancy (N). Kualitas gum rosin yang dihasilkan di PT Inhutani V masih berada pada grade window glass (WG) berwarna kuning kecoklatan dengan nilai 7-8 scale gardner, sehingga perlu untuk ditingkatkan kualitasnya untuk meningkatkan harga jual. Reaksi browning merupakan proses pembentukan pigmen berwarna coklat dari yang awalnya berwarna jernih. Natrium metabisulfit merupakan senyawa sulfit yang mampu menghambat terjadinya reaksi browning melalui reaksi pemecahan polimer. Penelitian ini bertujuan untuk mengetahui pengaruh penambahan natrium metabisulfit pada reaksi browning terhadap kualitas gum rosin. Variabel penelitian yang digunakan adalah konsentrasi larutan natrium metabisulfit sebesar 0,3%, 0,6%, dan 0,9% (volume) dengan lama waktu perendaman getah pinus 60 menit. Proses pembuatan gum rosin menggunakan metode distilasi selama 3 jam dengan suhu maksimal 175℃. Hasil penelitian menunjukkan bahwa semakin besar konsentrasi natrium metabisulfit, maka semakin rendah kadar warna sehingga warna gum rosin yang dihasilkan semakin jernih. Konsentrasi larutan natrium metabisulfit yang paling optimal yaitu 0,9%, dimana menghasilkan nilai warna sebesar 4,9 scale gardner; bilangan asam 201,8 KOH/gram; Non Volatile 98,8%; Softening Point 79℃ dan tergolong grade extra white (X). Peningkatan kualitas gum rosin menunjukkan bahwa penambahan natrium metabisulfit mampu menghambat pembentukan warna coklat pada gum rosin.
Construction of geriatric hypoalbuminemia predicting model for hypoalbuminemia patients with and without pneumonia and explainability analysis
Authors: Liu Ziqi , Kang Qi , Mi Zhilong , Yuan Yuan , Sang Tiantian , Guo Binghui , Zheng Zhiming , Yin Ziqiao , Tian Wei 
Published: December 2024

Background and objectivesPneumonia portrays a critical health concern in geriatrics. Geriatric pneumonia can lead to changes on other complications, in which hypoalbuminemia is a common complication. However, few studies have looked at the impact of pneumonia on the course of hypoalbuminemia and predicting. This study aims to predicting hypoalbuminemia in geriatric pneumonia and non-pneumonia patients and exploring the clinical difference between the two groups.Materials and methodsThis retrospective study enrolled 42 pneumonia patients group and 76 non-pneumonia patients group. The indicators difference of different groups were analyzed, then a mutual information-grey relational coefficient gradual fusion model was constructed to predict hypoalbuminemia in the future by the indicators of vital signs, N-Terminal Pro-Brain Natriuretic Peptide, blood routine examination and urine routine examination at admission. Through the sensitivity analysis of model, we analysed the important of four examines in patients with and without pneumonia.ResultsThe predicted accuracy of our gradual fusion model was 0.954, which improve the prediction accuracy by nearly 17.6% compared with the classical machine learning method. The AUC of gradual fusion model was 0.96 and 0.9 in hypoalbuminemia patients with and without pneumonia. The sensitivity analysis of gradual fusion model showed blood routine examine was most important to predict hypoalbuminemia in patients with pneumonia, while urine routine examine was most important to predict hypoalbuminemia in non-pneumonia patients.ConclusionThe changes in the blood of patients with hypoalbuminemia combined with pneumonia were more significant than that of patients with hypoalbuminemia alone, which was characterized by abnormal excretion due to low protein. We suggested doctors should pay more attention to blood routine results when preventing hypoalbuminemia in patients with pneumonia and pay more attention to urine routine examine results when preventing hypoalbuminemia in patients without pneumonia.
Quantitative analysis of retinal vascular parameters changes in school-age children with refractive error using artificial intelligence
Authors: Liu Linlin , Zhong Lijie , Zeng Linggeng , Liu Fang , Yu Xinghui , Xie Lianfeng , Tan Shuxiang , Zhang Shuang , Jiang Yi-Ping 
Published: December 2024

AimTo quantitatively analyze the relationship between spherical equivalent refraction (SER) and retinal vascular changes in school-age children with refractive error by applying fundus photography combined with artificial intelligence (AI) technology and explore the structural changes in retinal vasculature in these children.MethodsWe conducted a retrospective case–control study, collecting data on 113 cases involving 226 eyes of schoolchildren aged 6–12 years who attended outpatient clinics in our hospital between October 2021 and May 2022. Based on the refractive spherical equivalent refraction, we categorized the participants into four groups: 66 eyes in the low myopia group, 60 eyes in the intermediate myopia group, 50 eyes in the high myopia group, and 50 eyes in the control group. All participants underwent a series of examinations, including naked-eye and best-corrected visual acuity, cycloplegic spherical equivalent refraction, intraocular pressure measurement, ocular axial measurement (AL), and color fundus photography. Using fundus photography, we quantitatively analyzed changes in the retinal vascular arteriovenous ratio (AVR), average curvature, and vascular density with AI technology. Data were analyzed using the χ2 test and one-way analysis of variance.ResultsThe AVR in the low myopia group, moderate myopia group, high myopia group, and control group were 0.80 ± 0.05, 0.80 ± 0.04, 0.76 ± 0.04, and 0.79 ± 0.04, respectively, and the vessel densities were 0.1024 ± 0.0076, 0.1024 ± 0.0074, 0.0880 ± 0.0126, and 0.1037 ± 0.0143, respectively The difference between the AVR and vascular density in the high myopia group was statistically significant compared to the other three groups (p &lt; 0.05). Linear correlation analysis showed a strong negative correlation between the spherical equivalent refraction and the ocular axis (r = −0.874, p &lt; 0001), a moderate positive correlation between the spherical equivalent refraction and the vascular density (r = 0.527, p &lt; 0001), and a moderate negative correlation between the ocular axis and the vascular density (r = −0.452, p &lt; 0001).ConclusionSchoolchildren with high myopia showed a decreased AVR and decreased vascular density in the retinal vasculature. The AVR and vascular density may be early predictors of myopia progression.
Virtual screening and evaluation of bioactive peptides from Haliotis discus hannai as potential HMGCR inhibitors for hyperlipidemia treatment
Authors: Qiao Kun , Liu Lina , Chen Yihui , Huang Qiongmei , Chen Bei , Wu Jingna , Huang Wenmei , Liu Zhiyu 
Published: December 2024

IntroductionHyperlipidemia remains a major disease threatening global public health. The morbidity and mortality associated with cardiovascular diseases have been increasing. The inhibition of 3-Hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR), a key enzyme in the cholesterol synthesis pathway, can effectively reduce cholesterol levels.Methods and resultsIn this study, the most suitable protease for preparing HMGCR inhibitory peptides was screened using the evaluation indexes of peptide yield and HMGCR inhibition rate. Peptide sequences with molecular weights &lt;1 kDa were identified, and peptide fragments were docked with HMGCR for virtual screening. The inhibitory effects of these peptides on HMGCR activity were evaluated in vitro using a high-fat Hep-G2 cell model. The screened peptides possessed significant HMGCR inhibitory activity and reduced cholesterol micelle solubility and total cholesterol and triglyceride levels in hyperlipidemic Hep-G2 cells.ConclusionThis study provides novel insights into developing natural drugs for hyperlipidemia; moreover, the results will facilitate the functional application of marine bioactive peptides.
Effectiveness of interventions to prevent drowning among children under age 20 years: a global scoping review
Authors: Ashraf Lamisa , Zia Nukhba , Vincenten Joanne , Mackay J. Morag , Agrawal Priyanka , Green Abigail , Bachani Abdulgafoor M. 
Published: December 2024

BackgroundDrowning is a leading cause of death among young children. The United Nations Resolution on global drowning prevention (2021) and World Health Assembly Resolution in 2023 have drawn attention to the issue. This scoping review synthesizes the current evidence on the effectiveness of child drowning prevention interventions since the 2008 World Report on Child Injury Prevention and implications for their implementation.MethodsQuantitative studies published between 2008 and 2023 focusing on interventions targeting unintentional injuries, including drowning, among children and adolescents under age 20 years were searched on Cochrane Database of Systematic Reviews, Epistemonikos, PubMed, and Embase. Relevant data on interventions were extracted using a pre-defined template on Microsoft Excel. This scoping review focuses on the interventions addressing drowning.ResultsOverall, 12 studies fulfilled the inclusion criteria. Evidence generated between 2008 and 2023 support the effectiveness of introducing barriers around water bodies, immediate resuscitation and first-responder training, and use of personal floatation devices (PFDs). Basic swimming and water safety skills training for children ages 6 years and older, and enacting and enforcing regulations on pool fencing and PFD use were found to be promising based on new evidence published since 2008. This scoping review also found evidence on new interventions studied since 2008, such as close adult supervision, inspections of safety standards of pools, and the use of door barriers and playpens, all of which demand further research to ensure context-specific implementation in LMICs.ConclusionWhile there is evidence to support both existing and new interventions, most of the available interventions are still classified as promising and emerging, underlining the need for further evaluation of those interventions in diverse settings (including low and middle- income) through effectiveness studies and implementation research. In addition, it is important to highlight the nexus between drowning prevention and the Sustainable Development Goals to advocate multisectoral and interdisciplinary collaboration, to influence the broader child health agenda.