bluuebunny/crossref_metadata_2025_split huggingface dataset:
Home-Based Cardiac Rehabilitation
Authors: Drwal Kariann R. , Wakefield Bonnie J. , Forman Daniel E. , Wu Wen-Chih , Haraldsson Bjarni , El Accaoui Ramzi N. 
Published: March 2021

Purpose:
The conceptual utility of home-based cardiac rehabilitation (HBCR) is widely acknowledged. However, data substantiating its effectiveness and safety are limited. This study evaluated effectiveness and safety of the Veterans Affairs (VA) national HBCR program.

Methods:
Veterans completed a 12-wk HBCR program over 18 mo at 25 geographically dispersed VA hospitals. Pre- to post-changes were compared using paired t tests. Patient satisfaction and adverse events were also summarized descriptively.

Results:
Of the 923 Veterans with a mean age of 67.3 ± 10.6 yr enrolled in the HBCR program, 572 (62%) completed it. Findings included significant improvements in exercise capacity (6-min walk test distance: 355 vs 398 m; P < .05; Duke Activity Status Index: 27.1 vs 33.5; P < .05; self-reported steps/d: 3150 vs 4166; P < .05); depression measured by Patient Health Questionnaire (6.4 vs 4.9; P < .0001); cardiac self-efficacy (33.1 vs 39.2; P < .0001); body mass index (31.5 vs 31.1 kg/m2; P = .0001); and eating habits measured by Rate Your Plate, Heart (47.2 vs 51.1; P < .05). No safety issues were related to HBCR participation. Participants were highly satisfied.

Conclusions:
The VA HBCR program demonstrates strong evidence of effectiveness and safety to a wide range of patients, including those with high clinical complexity and risk. HBCR provides an adjunct to site-based programs and access to cardiac rehabilitation. Additional research is needed to assess long-term effects, cost-effectiveness, and sustainability of the model.
Cross-species data integration to prioritize causal genes in lipid metabolism
Authors: Votava James A. , Parks Brian W. 
Published: March 2021

Purpose of review
More than one hundred loci have been identified from human genome-wide association studies (GWAS) for blood lipids. Despite the success of GWAS in identifying loci, subsequent prioritization of causal genes related to these loci remains a challenge. To address this challenge, recent work suggests that candidate causal genes within loci can be prioritized through cross-species integration using genome-wide data from the mouse.

Recent findings
Mouse model systems provide unparalleled access to primary tissues, like the liver, that are not readily available for human studies. Given the key role the liver plays in controlling blood lipid levels and the wealth of liver genome-wide transcript and protein data available in the mouse, these data can be leveraged. Using coexpression network analysis approaches with mouse genome-wide data, coupled with cross-species analysis of human lipid GWAS, causal genes within lipid loci can be prioritized. Prioritization through both mouse and human along with biochemical validation provide a systematic and valuable method to discover lipid metabolism genes.

Summary
The prioritization of causal lipid genes within GWAS loci is a challenging process requiring a multidisciplinary approach. Integration of data types across species, such as the mouse, can aid in causal gene prioritization.
Nasal vestibule and columella cancer: a therapeutic and reconstructive conundrum
Authors: Iyer Subramania , Akali Nisha R. , Rao N. Nageswara 
Published: March 2021

Purpose of review
Nasal vestibular cancers are rare entities among the head and neck cancers. The treatment options are varied. Although surgical treatment plays an important role, postablative defects are difficult to reconstruct. This review aims to discuss the current views in the management of these cancers and issues related to the reconstruction of the complex surgical defects.

Recent findings
Nasal vestibular cancers are a distinct rare entity of head and neck cancers. These cancers are staged using the AJCC-TNM system for nonmelanoma cutaneous cancers of head and neck or the Wang classification. Early lesions are best treated by either surgery or radiation giving excellent cure rates. Advanced stages tumours need combined treatment with surgery and adjuvant radiation therapy. Primary radiation therapy can be offered by external beam or interstitial brachytherapy. Surgical treatment varies from endonasal resections, Mohs’ chemosurgery to open excisions.

Summary
Even though the Wang system of classification is used by majority of reports due its clinical utility, it has a drawback of not taking into account the tumour size as done by the AJCC system. Brachytherapy has been reported to be offering excellent cure rates with low morbidity in early tumours. Surgical treatment is also effective in early lesions, but its role is more established in advanced lesions. Reconstruction of the surgical defects is often a challenge, to preserve functional integrity and cosmesis. Various techniques, including skin grafts, local flaps, free flaps and prosthetics, form part of the reconstructive armamentarium.
Experience of Comprehensive Three Dimensional Epicanthoplasty With Upper Blepharoplasty in Asian Patients
Authors: Aung Zin Mar , Yang Xianxian , Chen Xiaojun , Jun Mooi Wei , Zhang Yan , Han Dong , Chai Gang , Xu Haisong 
Published: March 2021

Purpose
To introduce the experience of comprehensive 3-dimensional epicanthoplsty with upper blepharoplasty in Asian patients.

Methods
The patients who underwent comprehensive 3-dimensional epicanthoplsty with upper blepharoplasty at the Shanghai Ninth People's hospital from January 2018 to January 2019 were included in our study. The interepicanthal distance was evaluated preoperatively and 6 months after the surgery, scar visibility and patient's satisfaction were documented 6 months after the surgery.

Results
A total of 72 patients (144 eyelids) were included in this study with ages ranging from 18 to 37 years (mean, 23.83 ± 4.64 years) and follow-up duration ranging from 6 to 12 months (mean, 7.82 ± 1.92 months). All patients were female and achieved esthetically favorable results without serious complications. No patients required revision surgery showing high patient satisfaction (score, 4.4). The preoperative mean interepicanthal distance was 33.13 ± 2.25 mm and decreased to 29.28 ± 2.26 mm postoperatively showing statistical significance (P < 0.001). Twenty-nine (40.3%) patients had no visible scarring, and 42 (58.3%) patients had minimal scarring, which was accepted by the patients.

Conclusions
The comprehensive 3-dimensional epicanthoplasty with upper blepharoplasty is a surgical technique that is easy to perform, reliable, and effective in treatment of all types of epicanthal folds except type 4 with increase intercanthal distance, less visible scar, and high patient satisfaction in Asian patients.
Reduction Malarplasty With Subperiosteal Lift Via a Single Limited Temporal Incision
Authors: Gao Wei , Qiu Yajing , Zou Yun , Qiao Congzhen , Chang Lei , Jin Yunbo , Chen Hui , Lin Xiaoxi 
Published: March 2021

Introduction
Different from Western culture, prominent zygoma and rectangular facial contour are deemed as unaesthetic and masculine in Asians. To achieve an ideal oval facial shape, reduction malarplasty is often performed.

Methods
Twenty-two eligible patients who underwent reduction malarplasty between November 2008 and December 2018 were reviewed. The reduction malarplasty involved repositioning of the osteotomized zygomatic arch and subperiosteal lift via a limited temporal incision. Photographs were collected both preoperatively and postoperatively. Complications and postoperative outcomes were evaluated.

Results
Twenty-two patients underwent reduction malarplasty with subperiosteal lift between November 2008 and December 2018. Their mean age was 35 ± 2.30 years. Prominent zygoma and facial contour were significantly improved after surgery. Patients demonstrated satisfaction with outcome (73.77 ± 6.83) and with facial appearance (75.00 ± 5.60). No cheek drooping and major complications were observed during the long-term follow-up.

Conclusions
Prominent zygoma treated with reduction malarplasty with subperiosteal lift via limited temporal incision has a stable and long-lasting effect. This approach can be regarded as a true alternative for facial contour reshaping.
Clinical course and outcomes of critically ill COVID-19 patients in two successive pandemic waves
Authors: Chalkias Athanasios , Pantazopoulos Ioannis , Papagiannakis Nikolaos , Skoulakis Anargyros , Laou Eleni , Kolonia Konstantina , Ntalarizou Nicoletta , Ragias Dimitrios , Kampolis Christos , García de Guadiana Romualdo Luis , Tourlakopoulos Konstantinos , Pagonis Athanasios , Hayek Salim S , Eugen-Olsen Jesper , Gourgoulianis Konstantinos , Arnaoutoglou Eleni 
Published: March 2021

AbstractRationaleThe progress of COVID-19 from moderate to severe may be precipitous, while the heterogenous characteristics of the disease pose challenges to the management of these patients.ObjectivesTo characterize the clinical course and outcomes of critically ill patients with COVID-19 during two successive waves.MethodsWe leveraged the multi-center SuPAR in Adult Patients With COVID-19 (SPARCOL) study and collected data from consecutive patients requiring admission to the intensive care unit from April 1st to December 31st, 2020.Measurements and Main ResultsOf 252 patients, 81 (32%) required intubation and mechanical ventilation. Of them, 17 (20.9%) were intubated during the first wave, while 64 (79%) during the second wave. The most prominent difference between the two waves was the overall survival (first wave 58.9% vs. second wave 15.6%, adjusted p-value=0.006). This difference is reflected in the prolonged hospitalization during the first wave. The mean ICU length of stay (19.1 vs. 11.7 days, p=0.022), hospital length of stay (28.5 vs. 17.1 days, p=0.012), and days on ventilator (16.7 vs. 11.5, p=0.13) were higher during the first wave. A significant difference between the two waves was the development of bradycardia. In the first wave, 2 (11.7%) patients developed sinus bradycardia only after admission to the intensive care unit, while in the second wave, 63 (98.4%) patients developed sinus bradycardia during hospitalization.ConclusionsSurvival of critically ill patients with COVID-19 was significantly lower during the second wave. The majority of these patients developed sinus bradycardia during hospitalization.
What matters for employees’ daily interpersonal behaviors?
Authors: Park In-Jo , Kim Peter B. , Hai Shenayang , Zhang Xiaomin 
Published: March 2021

PurposeThis study aims to investigate the impact of service employees’ agreeableness personality and daily self-esteem on their daily interpersonal behaviors in terms of interpersonal harmony and counterproductive work behavior toward other individuals (CWB-I). Furthermore, this study examines whether the impact of daily self-esteem on daily interpersonal behaviors is moderated by the quality of service employees’ relationship with their manager and leader–member exchange (LMX).Design/methodology/approachUsing a sample of 111 restaurant employees in China who took daily surveys with 1,412 ratings for 10 consecutive days, a longitudinal analysis was conducted to test the research hypotheses using hierarchical linear modeling.FindingsThe results show that agreeableness personality predicted daily interpersonal harmony but had no significant effect on daily CWB-I. It was also found that daily self-esteem predicted both daily interpersonal harmony and daily CWB-I, and LMX moderated the effect of daily self-esteem on daily interpersonal behaviors.Practical implicationsGiven the fluctuation of employees’ interpersonal behaviors, organizations should guide the variability of interpersonal behaviors in the positive direction. To promote daily interpersonal harmony and reduce daily CWB-I, managers could focus on recruiting employees with agreeableness, offering daily self-esteem training and enhancing the quality of LMX.Originality/valueThis research is unique in its objectives to examine what influences service employees’ interpersonal behaviors on a daily basis and its methods to implement a longitudinal approach unlike previous studies that often relied on cross-sectional designs to enhance the ecological validity of the findings.
COVID-19 and lack of socialization: does service innovation become an imperative for universities?
Authors: Easa Nasser Fathi , Bazzi Ayman Mahmoud 
Published: March 2021

PurposeThis paper aims to examine the moderated mediation effect of the lack of students’ socialization (as one of the COVID-19 consequences) and the university reputation on the relationship between the service innovation and students satisfaction. The relationship between students satisfaction and their loyalty is also examined.Design/methodology/approachThis study adopts a quantitative research approach, whereas the study population consists of all universities’ students in Lebanon. Data were collected from 201 students, elected depending on snowballing sample technique. A questionnaire was used to gather data, whereby partial least squares structural equation modeling was used to check the proposed scales validity and the relationships between the study variables.FindingsThe findings reveal a significant direct effect for university’s service innovation on students satisfaction and an indirect effect through the mediation role for university reputation. Moreover, an evidence for weak negative significant effect for lack of socialization on students satisfaction exists. Whereby, lack of socialization does not moderate the relationship between university service innovation and students satisfaction. Finally, students satisfaction has a significant positive effect on their loyalty.Originality/valueThis paper advances the service innovation literature in the higher education sector. In addition, the paper might be the first paper to address the influence of lack of socialization as one of the COVID-19 consequences on students satisfaction. Furthermore, areas for future research are suggested.
A perspective of making India robot ready: case study on Sakrobotix lab pvt. ltd.
Authors: Mishra Siwalik , Bhattacharya Sonali 
Published: March 2021

Purpose
The purpose of this study is to identify and understand key strategies relating to the staffing, employee experience and employer branding of an inventive startup in robotics training and consumer robotics manufacturing space, keeping in mind the constraints and challenges faced by the company right from the beginning to date.

Design/methodology/approach
A case-based method approach has been used. The Founder-Chief executive officer was interviewed multiple times. Interviews were transcribed for further analysis. Data was also sourced from the company website, news and digital media reports.

Findings
Human resource strategies used by the company in venturing out in this niche market were explored and linked to the concepts of staffing, employee experience and employer branding. This case can be used for teaching the human resource challenges of a growing start-up.

Practical implications
With the help of this case, readers may be able to appreciate the practice of critical concepts of staffing and employee experience in a growing startup.

Originality/value
The premise of a budding start-up in a niche industry, such as robotics training in educational institutions and manufacturing of small-scale consumer robotics, adds to the novelty of the case.
Insurance and economic growth in Ghana
Authors: Osei-Bonsu Andrews , Abotsi Anselm Komla , Carsamer Emmanuel 
Published: March 2021

PurposeThe Ghanaian insurance industry has been transformed significantly from state-led to a market-driven one over the past decades. The empirical literature on the causal relationship between insurance and economic growth has been mixed, but little study on this has been done in Ghana. This study therefore empirically examines the effect of the growing insurance industry on the economic growth in Ghana.Design/methodology/approachQuantitative research design was deployed in the study. The study used Johansen–Juselius cointegration test and vector error correction model. The study deployed quarterly data from the first quarter of 2006 to the second quarter of 2018 sourced from the World Bank (World Development Indicators), National Insurance Commission, Ghana Statistical Service and Bank of Ghana.FindingsFindings revealed that there is a significant and positive short and long-run relationship between insurance and economic growth in Ghana, bidirectional causality between insurance and economic growth and also a long-run effect of innovations (shocks) in insurance on economic growth.Research limitations/implicationsOne of the limitations of the study is the unavailability of quarterly data of some of the variables.Practical implicationsThe study recommends the development and implementation of policies that promote an increase in coverage and access to insurance products to enhance economic growth.Originality/valueThe study finds a bidirectional causality running from insurance premium to economic growth and from economic growth to insurance which is consistent with the feedback hypothesis in the case of Ghana. Impulse response functions and the variance decompositions revealed that innovation (shock) in the insurance industry has a positive impact on economic growth.
Determinants of Islamic banking products and services adoption in Morocco: a conceptual framework
Authors: El Mallouli Amal , Sassi Hassan 
Published: March 2021

Purpose
The Moroccan monetary authorities have implemented an Islamic banking system since 2017 as an alternative to the conventional system. However, the adoption of Islamic banking products and services is not widely accepted by customers. The purpose of this study is to propose a conceptual framework to understand the determinants of Islamic banking products and services adoption in Morocco.

Design/methodology/approach
This study develops a conceptual framework based on the diffusion of innovation theory (DOI). Thus, with reference to an extensive literature review done regarding adoption studies, the proposed research model integrates perceived attributes of innovation (relative advantage, compatibility, complexity and observability) suggested by the DOI theory. It also integrates other relevant variables that should be considered in the context of this study. These include knowledge, perceived risk and customer involvement.

Findings
The proposed conceptual framework demonstrates and justifies the relevance and the applicability of Rogers’ DOI to understand consumer decisions to adopt an innovation in general as well as Islamic banks in particular.

Originality/value
Several studies have examined the factors influencing the adoption of Islamic banks; however, those carried out in the Moroccan context remain very limited. The majority of these studies examine the intention to adopt in the future, whereas the present study seeks to establish a conceptual research model that examines the determinants of current adoption of Islamic banking in Morocco and the continuity of this adoption over time. The novelty of this study is to develop a modified model based on DOI theory which, according to the existing literature, has not yet been tested in the Moroccan context.
Germination and emergence of Astrodaucus orientalis (L.) Drude populations influenced by environmental factors and seed burial depth
Authors: Amini Rouhollah , Ebrahimi Atefeh , Dabbagh Mohammadi Nasab Adel 
Published: March 2021

AbstractAstrodaucus orientalis is a weed species in cropping systems and rangelands in Iran. The effects of temperature, light, NaCl concentration, water potential, seed burial depth and crop residue cover were assessed on seed germination and seedling emergence of two populations of A. orientalis from Ardabil (Meshginshahr population) and East Azarbayjan (Tabriz population) provinces of Iran. The A. orientalis populations indicated different responses to environmental factors and burial depth. In the Tabriz population the greatest germination (88.5%) was observed in 20/12°C day/night temperature but in the Meshginshahr population (83.2%) it was obtained in 24/16°C day/night temperature. Over a broad range of light period (10–24 hr light) germination was 74–83%, but it decreased (less than 37%) under 24 hr dark in both A. orientalis populations. With respect to water potential, the C50 parameters were −0.62 and − 0.49 MPa for Tabriz and Meshginshahr populations, respectively. The D50 parameters (the burial depth that caused 50% decrease in emergence) for Tabriz and Meshginshahr populations were 2.42 and 3.13 cm, respectively. Generally, the results showed that emergence of both populations of A. orientalis was delayed as depth of burial increased up to 4 cm and in cropping systems a shallow tillage that locates the seeds to >4 cm of depth in soil could be used in order to suppress seedling emergence. Our findings also could be useful in integrated management of A. orientalis in winter annual crops and rangelands.
Alcohol policy and gender: a modelling study estimating gender‐specific effects of alcohol pricing policies
Authors: Meier Petra S. , Holmes John , Brennan Alan , Angus Colin 
Published: March 2021

AbstractAimsTo describe gender differences in alcohol consumption, purchasing preferences and alcohol‐attributable harm. To model the effects of alcohol pricing policies on male and female consumption and hospitalizations.DesignEpidemiological simulation using the Sheffield Alcohol Policy Model version 4.Setting and ParticipantsAdults aged 18+ years, England.InterventionsThree alcohol pricing policies: 10% duty increase and minimum unit prices (MUP) of £0.50 and £0.70 per UK unit.MeasuresGender‐specific baseline and key outcomes data: annual beverage‐specific units of alcohol consumed and beverage‐specific alcohol expenditure (household surveys). Alcohol‐attributable hospital admissions (administrative data). Key model parameters: literature‐based own‐ and cross‐price elasticities for 10 beverage‐by‐location categories (e.g. off‐trade beer). Sensitivity analysis with new gender‐specific elasticities. Literature‐based risk functions linking consumption and harm, gender‐disaggregated where evidence was available. Population subgroups: 120 subgroups defined by gender (primary focus), age, deprivation quintile and baseline weekly consumption.FindingsWomen consumed 59.7% of their alcohol as off‐trade wine while men consumed 49.7% as beer. Women drinkers consumed fewer units annually than men (494 versus 895) and a smaller proportion of women were high‐risk drinkers (4.8 versus 7.2%). Moderate drinking women had lower hospital admission rates than men (44 versus 547 per 100 000), but rates were similar for high‐risk drinking women and men (14 294 versus 13 167 per 100 000). All three policies led to larger estimated reductions in consumption and admission rates among men than women. For example, a £0.50 MUP led to a 5.3% reduction in consumption and a 4.1% reduction in admissions for men but a 0.7% reduction in consumption and a 1.6% reduction in hospitalizations for women.ConclusionAlcohol consumption, purchasing preferences and harm show strong gender patterns among adult drinkers in England. Alcohol pricing policies are estimated to be more effective at reducing consumption and harm for men than women.