bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tele-rehabilitation of upper-extremity hemiparesis after stroke: Proof-of-concept randomized controlled trial of in-home Constraint-Induced Movement therapy
Authors: Uswatte Gitendra , Taub Edward , Lum Peter , Brennan David , Barman Joydip , Bowman Mary H. , Taylor Andrea , McKay Staci , Sloman Samantha B. , Morris David M. , Mark Victor W. 
Published: August 2021

Background: Although Constraint-Induced Movement therapy (CIMT) has been deemed efficacious for adults with persistent, mild-to-moderate, post-stroke upper-extremity hemiparesis, CIMT is not available on a widespread clinical basis. Impediments include its cost and travel to multiple therapy appointments. To overcome these barriers, we developed an automated, tele-health form of CIMT. Objective: Determine whether in-home, tele-health CIMT has outcomes as good as in-clinic, face-to-face CIMT in adults ≥1-year post-stroke with mild-to-moderate upper-extremity hemiparesis. Methods: Twenty-four stroke patients with chronic upper-arm extremity hemiparesis were randomly assigned to tele-health CIMT (Tele-AutoCITE) or in-lab CIMT. All received 35 hours of treatment. In the tele-health group, an automated, upper-extremity workstation with built-in sensors and video cameras was set-up in participants’ homes. Internet-based audio-visual and data links permitted supervision of treatment by a trainer in the lab. Results: Ten patients in each group completed treatment. All twenty, on average, showed very large improvements immediately afterwards in everyday use of the more-affected arm (mean change on Motor Activity Log Arm Use scale = 2.5 points, p < 0.001, d′ = 3.1). After one-year, a large improvement from baseline was still present (mean change = 1.8, p < 0.001, d′ = 2). Post-treatment outcomes in the tele-health group were not inferior to those in the in-lab group. Neither were participants’ perceptions of satisfaction with and difficulty of the interventions. Although everyday arm use was similar in the two groups after one-year (mean difference = –0.1, 95% CI = –1.3–1.0), reductions in the precision of the estimates of this parameter due to drop-out over follow-up did not permit ruling out that the tele-health group had an inferior long-term outcome. Conclusions: This proof-of-concept study suggests that Tele-AutoCITE produces immediate benefits that are equivalent to those after in-lab CIMT in stroke survivors with chronic upper-arm extremity hemiparesis. Cost savings possible with this tele-health approach remain to be evaluated.
Implementasi Blackbox Testing Pada Aplikasi Real-Time Thermal Video Detection (Studi Kasus Deteksi Demam/Covid-19)
Authors: Yudhistiro Kukuh , Sulaksono Aditya Galih , Pratama Aditya Hidayat 
Published: August 2021

Seiring munculnya pandemi Covid-19 yang vaksinnya belum tersebar secara merata, seluruh negara di dunia khususnya Indonesia telah melakukan beberapa langkah preventif guna menghambat penyebaran virus tersebut. Salah satu tindakan awal adalah melakukan deteksi setiap orang yang keluar masuk ke dalam negeri melalui bandara maupun transportasi darat. Tindakan dini tersebut dilakukan dengan mendeteksi suhu tubuh dari warga yang melalui lokasi-lokasi keluar masuk seperti bandara udara, dan stasiun kereta api. Deteksi pada umumnya dilakukan menggunakan thermal gun berbentuk alat tembak infrared yang diarahkan ke individu yang melewati pemeriksaan. Pada riset ini dibahas rangkaian alat yang terdiri dari kamera dengan sensor thermal dimana data hasil capture akan diolah melalui perangkat lunak yang menampilkan histogram suhu bagian dada hingga kepala seseorang secara realtime. Setiap hasil capture digunakan sebagai dataset yang dapat digunakan untuk kebutuhan tracing pengunjung tempat publik. Pada riset ini akan membahas pengujian fungsional (blackbox) dari aplikasi thermal video detection pada studi kasus deteksi demam.
Perbandingan Hasil Klasifikasi Jenis Daging Menggunakan Ekstraksi Ciri Tekstur Gray Level Co-occurrence Matrices (GLCM) Dan Local Binary Pattern (LBP)
Authors: Neneng Neneng , Puspaningrum Ajeng Savitri , Aldino Ahmad Ari 
Published: August 2021

Daging memiliki nilai gizi tinggi yang banyak dikonsumsi oleh manusia. Kandungan yang terdapat dalam daging meliputi protein, vitamin, mineral, lemak, dan zat lainnya yang sangat dibutuhkan di dalam tubuh sehingga dapat melaksanakan kegiatan setiap harinya. Akan tetapi sayangnya tidak semua masyarakat bisa membedakan jenis daging tersebut, dikarenakan tekstur dan warnanya yang hampir mirip. Hal ini juga kerap dimanfaatkan oleh penjual daging yang tidak bertanggungjawab dengan mencampur jenis daging tersebut atau dengan jenis daging lain untuk mendapatkan keuntungan yang besar. Padahal tidak semua orang bisa mengkonsumsi jenis daging tertentu karena alasan penyakit yang diderita. Penelitian yang dilakukan ini membandingkan metode GLCM dan LBP untuk klasifikasi citra jenis daging berdasarkan analisis tekstur. Jenis citra daging yang diklasifikasi adalah daging kambing, kerbau, dan kuda. Data citra daging tersebut diperoleh dengan cara mengambil gambar secara manual menggunakan kamera digital yakni Nikon D3200. Citra tersebut diambil dengan jarak 20 cm. Pengujian dan pelatihan data dilakukan dengan metode Support Vector Machine (SVM). Ciri tekstur yang digunakan adalah ASM, IDM, entropi, kontras, serta korelasi. Hasil akurasi klasifikasi citra daging kambing, kerbau, dan kuda menggunakan metode GLCM adalah sebesar 75,6%. Sedangkan hasil akurasi klasifikasi menggunakan metode LBP adalah sebesar 85,6%. Dengan demikian, metode ekstraksi ciri tekstur LBP lebih direkomendasikan untuk klasifikasi jenis daging menggunakan ciri tekstur.
Analyzing Complex Predicates in Karo Language using Syntactic Parsing
Authors: Tarigan Karisma Erikson , Stevani Margaret 
Published: August 2021

This study characterized the complex predicate and multiple events where the multi-verb single clause realises a single event in syntax and examined the complex sentences containing multiple verbal predicates. This study used the descriptive qualitative method. The data sources used were sentences containing karo sentence clauses and was classified based on the elements of complex Predicates in a tree diagram and the RRG account of nexus-juncture relations theory by Nolan, 2005 & Van Valin, 2005. The findings showed that event, argument, and semantic could be realized in syntactic meaning to reveal complex predicates. The tightest syntactic linkages embodied the closer semantic relations and it was signaled by word order. Most of the complex predicates in Karo language have an embedded object. The core in the nucleus could be appeared not only as one core but two or more complex predicates and it followed by an argument with the form V+V+N and in the form of V+V+N. One argument (Participant/Actor) that involved one core. It assumed that there might be one participant in two events, and there may be two participants in one event. All of Karo language sentences have at least one NP + one VP and they consisted of more than one complex predicates.
Avaliação do tratamento integrativo no controle de parasitas gastrintestinais de ovinos
Authors: Pereira Jairo Edésio Gonçalves , Pereira Michelli , Magalhães Rebeca Gonçalves de Lima , Melotti Ricardo Passamani , Rizzomi Leandro Becalete , Guedes Elizângela , Garcia José Antônio Dias 
Published: August 2021

Um dos principais entraves para o crescimento do rebanho ovino são as perdas ocasionadas pelas helmintoses gastrintestinais. Deste modo, o presente estudo teve como objetivo avaliar o efeito de dois tratamentos antiparasitários para ovinos infectados naturalmente, usando um tratamento alopático Cloridrato de Levamisol 5% e um tratamento homeopático com o produto Homeocapriovi Verm 100, comparando as diferenças da contagem de ovos por grama de fezes (OPG) e oocistos por grama de fezes (OOPG) dos tratamentos e as concentrações séricas de proteínas totais, globulinas, albumina e a relação albumina/globulina dos tratamentos alopático e o homeopático na resposta imunológica frente às infecções parasitárias. Após análise dos resultados, tanto o produto alopático quanto o produto homeopático utilizado neste estudo preveniram o aumento de OPG para infecção por helmintos da ordem Strongylida e ambos os grupos não manifestaram sinais clínicos de coccidiose. Não houve diferença significativa entre os dois grupos na análise da média da concentração sérica das proteínas totais, albumina, globulina e a relação albumina/globulina. Embora o custo tenha sido mais elevado no tratamento homeopático, pode-se concluir que, o mesmo é uma alternativa eficiente no controle de parasitas do trato gastrintestinal de ovinos.
Three-dimensional study of the orbit-related structures according to sex, age and skeletal deformities
Authors: Castro Tamara Fernandes de , Iwaki Filho Liogi , Yamashita Amanda Lury , Yamashita Fernanda Chiguti , Santos Naiara Caroline Aparecido dos , Grossmann Eduardo , Chicarelli Mariliani , Iwaki Lilian Cristina Vessoni 
Published: August 2021

Objective: This study aimed to evaluate the relations between orbit-related structures and sex, age and skeletal deformities using cone-beam computed tomography (CBCT). Methods: This retrospective study evaluated 216 consecutive CBCT scans of patients, who were divided according to: sex (male, n=105; female, n=111), age (A1: 18-32 years, n=71; A2: 33-47 years, n=78; A3: 48-62 years, n=67), and skeletal deformities (Class I, n=70; Class II, n=75; Class III, n=71). The supraorbital foramen (SOF) location, volume of orbit, optic canal (OC) and infraorbital canal (IOC) were evaluated. Results were analyzed using the Gamma model test. The Tukey-Kramer post-hoc test was used to compare the variables with three factors (p<0.05). Results: The IOC volume showed higher values for male, A3 and class I patients. The SOF location and the orbital volume also showed higher values for male patients. Regarding the volume of CO, it showed higher values ​​for male and class I patients. Conclusions: According to our results, sex has been shown to have a significant influence on orbit-related structures. Age and skeletal deformities also influenced the volume of IOC and OC. These results eventually help the clinical practice, being useful for orbital reconstruction surgeries, anthropological studies, gender identification and identification of susceptibility to pathological conditions related to sexual dimorphism.
Avaliação físico-química e sensorial de pão de forma elaborado com farinha de palma forrageira (Opuntia ficus-indica)
Authors: Alves Simone de Andrade , Constant Patrícia Beltrão Lessa , Teles Alan Rodrigo Santos 
Published: August 2021

O estudo avaliou as características físico-químicas e sensoriais do pão de forma com adição de 0%(FP0), 5%(FP5), 10%(FP10) e 15%(FP15) de farinha de palma forrageira, em substituição à farinha de trigo branca. Os pães foram submetidos a análise sensorial de 106 (cento e seis) julgadores não treinados. O pão FP5 foi o mais aceito, com um índice de aceitabilidade de 75%. Foram realizadas análises de compostos fenólicos totais e atividade antioxidante pelo método da captura do radical ABTS•⁺, em FP0 e FP5, entretanto, as amostras analisadas não apresentaram, estatisticamente, diferença significativa entre si pelo teste de Tukey (p<0,05). Em FP5, a farinha da palma forrageira aumentou o teor de fibra e de micronutrientes, tais como cálcio (Ca), magnésio (Mg), potássio (K), zinco (Zn) e vitamina C, sem alterar os parâmetros texturométricos (p<0,05). O pão formulado com a farinha da palma forrageira pode ser uma alternativa de baixo custo para incorporar nutrientes importantes na dieta humana, entretanto, é necessário realizar estudos sobre a presença de fatores antinutricionais. Considerando o índice de aceitabilidade alcançado pelo pão de forma, incorporação da farinha da palma forrageira possibilita o aumento de micronutrientes importantes na dieta humana em valores bem superiores aos valores encontrados no pão de forma convencional. Apesar de a palma forrageira possuir coloração verde, essa característica não ofereceu resistência à aceitação do pão de forma por parte dos potenciais consumidores do produto e pode ser atrativo para crianças na fase pré-escolar.
Morphological and Molecular Features of Porcine Mesenchymal Stem Cells Derived From Different Types of Synovial Membrane, and Genetic Background of Cell Donors
Authors: Siengdee Puntita , Oster Michael , Reyer Henry , Viergutz Torsten , Wimmers Klaus , Ponsuksili Siriluck 
Published: August 2021

Graphical AbstractFlow chart of the experiment from cell isolation, culture conditions to morphological and molecular characterisation of synovial mesenchymal stem cells (SMSCs).
Elucidation of Charge Contribution in Iridium-Chelated Hydrogen-Bonding Systems
Authors: Balónová Barbora , Blight Barry A. 
Published: August 2021

We present two iridium complexes 1H+ and 2H+ that contain cationic ligands to extend the knowledge of charge-assisted hydrogen bonding (CAHB), which counts among the strongest non-covalent bonding interactions. Upon protonation, both complexes were converted into new hydrogen-bonding arrays with various selectivity for respective H-bonding partners. This study compares the association strengths of four hydrogen-bonding co-systems, emphasizing the roles of CAHB in supramolecular systems. We determined that the cationic charge in these systems contributed up to 2.7 kJ mol−1 in the H-bonding complexation processes.
Predictive Value of the Systemic Immune-Inflammation Index for Intravenous Immunoglobulin Resistance and Cardiovascular Complications in Kawasaki Disease
Authors: Liu Xiaoliang , Shao Shuran , Wang Lin , Zhang Nanjun , Wu Mei , Liu Lei , Zhao Li , Hua Yimin , Zhou Kaiyu , Luo Chunyan , Deng Yuxin , Wang Chuan 
Published: August 2021

Background: The prediction of intravenous immunoglobulin (IVIG) resistance and cardiovascular complications are critically clinical issues in Kawasaki disease (KD). This prospective study firstly aimed to determine the predictive ability of the systemic immune inflammation index (SII) for IVIG resistance and cardiovascular complications and compare the prognostic accuracy of SII with that of neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR).Methods: Patients with KD were divided into different groups according to the presence of IVIG resistance or cardiovascular complications (coronary artery lesions, valve regurgitation, myocarditis, pericardial effusion, and Kawasaki disease shock syndrome [KDSS]). The clinical and laboratory parameters were compared. Further analysis stratified by platelet level was performed. Multivariate logistic regression analysis was used to identify predictors for IVIG resistance and cardiovascular complications. The receiver operating characteristic (ROC) curve was applied to assess and compare the ability of SII, NLR, and PLR for predicting IVIG resistance and cardiovascular complications.Results: SII was significantly higher in KD patients with IVIG-resistance, myocarditis, valve regurgitation, and KDSS. It was identified as an independent risk factor for IVIG resistance, myocarditis, and valve regurgitation. For KD patients with thrombocytopenia, there were no significant differences in SII between KD patients with IVIG resistance/cardiovascular complications and those without. The best cutoff values of SII for IVIG resistance, myocarditis, valve regurgitation, and KDSS prediction in the whole cohort were 1331.4 × 109, 1368.6 × 109, 1002.4 × 109, and 1485.4 × 109, with a corresponding sensitivity of 0.525, 0.614, 0.754, and 0.670, a specificity of 0.711, 0.723, 0.584, and 0.730, respectively. The predictive value of SII for both IVIG resistance and cardiovascular complications were not superior to that of NLR.Conclusion: Although the parameter of SII may predict IVIG resistance, myocarditis, valve regurgitation, and KDSS in KD as a single parameter, its predictive ability was not good enough and not superior to NLR. SII might not be applicable in patients with KD having thrombocytopenia.
Prediction of Significant Coronary Artery Disease Through Advanced Echocardiography: Role of Non-invasive Myocardial Work
Authors: Sabatino Jolanda , De Rosa Salvatore , Leo Isabella , Strangio Antonio , Spaccarotella Carmen , Polimeni Alberto , Sorrentino Sabato , Di Salvo Giovanni , Indolfi Ciro 
Published: August 2021

Background: Non-invasive prediction of critical coronary artery stenosis (CAST) in patients with coronary artery disease (CAD) is challenging. Strain parameters can often capture an impairment of regional longitudinal function; however, they are load dependent. A novel non-invasive method to estimate Myocardial Work (MW) has been recently proposed, showing a strong correlation with invasive work measurements. Our aim was to investigate the ability of non-invasive MW to predict the ischaemic risk area underlying a CAST.Methods and Results: The study population comprises 80 individuals: 50 patients with CAST and 30 controls (CTRL). Echocardiography recordings were obtained before coronary angiography to measure global longitudinal strain (GLS), Myocardial Work Index (MWI), Myocardial Constructive Work (MCW), Myocardial Wasted work (MWW), Myocardial Work Efficiency (MWE). Global MWI (p = 0.048), MWE (p &lt; 0.001), and MCW (p = 0.048) at baseline were significantly reduced in patients with CAST compared to controls (p &lt; 0.05). Regional MWE within the myocardial segments underlying the CAST, but not LS, was significantly reduced compared to non-target segments (p &lt; 0.001). At ROC analysis, the diagnostic performance to predict CAST for regional MWE (AUC = 0.920, p &lt; 0.001) was higher compared to both regional post-systolic shortening index (PSI) (AUC = 0.600, p = 0.129) and regional LS (AUC = 0.546, p = 0.469).Conclusions: Non-invasive estimation of MW work indices is able to predict a CAST before invasive angiography.
A Novel Computed Tomography-Based Imaging Approach for Etiology Evaluation in Patients With Acute Coronary Syndrome and Non-obstructive Coronary Angiography
Authors: Ling Runjianya , Yu Lihua , Lu Zhigang , Li Yuehua , Zhang Jiayin 
Published: August 2021

Objective: This study sought to investigate the diagnostic value of dynamic CT myocardial perfusion imaging (CT-MPI) combined with coronary CT angiography (CCTA) in acute coronary syndrome (ACS) patients without obstructive coronary angiography.Methods: Consecutive ACS patients with normal or non-obstructive coronary angiography findings who had cardiac magnetic resonance (CMR) contraindications or inability to cooperate with CMR examinations were prospectively enrolled and referred for dynamic CT-MPI + CCTA + late iodine enhancement (LIE). ACS etiology was determined according to combined assessment of coronary vasculature by CCTA, quantified myocardial blood flow (MBF) and presence of LIE.Results: Twenty two patients were included in the final analysis. CCTA revealed two cases of side branch occlusion and one case of intramural hematoma which were overlooked by invasive angiography. High risk plaques were observed in 6 (27.3%) patients whereas myocardial ischemia was presented in 19 (86.4%) patients with varied extent and severity. LIE was positive in 13 (59.1%) patients and microvascular obstruction was presented in three cases with side branch occlusion or spontaneous intramural hematoma. The specific etiology was identified in 20 (90.9%) patients, of which the most common cause was cardiomyopathies (41%), followed by microvascular dysfunction (14%) and plaque disruption (14%).Conclusion: Dynamic CT-MPI + CCTA was able to reveal the potential etiologies in majority of patients with ACS and non-obstructive coronary angiography. It may be a useful alternative to CMR for accurate etiology evaluation.
Operating an eHealth System for Prehospital and Emergency Health Care Support in Light of Covid-19
Authors: Kyriacou Efthyvoulos , Antoniou Zinonas , Hadjichristofi George , Fragkos Prokopios , Kronis Chris , Theodosiou Theodosis , Constantinou Riana 
Published: August 2021

Introduction: The support of prehospital and emergency call handling and the impact of Covid-19 is discussed throughout this study. The initial purpose was to create an electronic system (eEmergency system) in order to support, improve, and help the procedure of handling emergency calls. This system was expanded to facilitate needed operation changes for Covid-19.Materials and Methods: An effort to reform the procedures followed for emergency call handling and Ambulance dispatch started on the Island of Cyprus in 2016; along that direction, a central call centre was created. The electronic system presented in this work was designed for this call centre and the new organization of the ambulance services. The main features are the support for ambulance fleet handling, the support for emergency call evaluation and triage procedure, and the improvement of communication between the call centre and the ambulance vehicles. This system started regular operation at the end of 2018. One year later, when Covid-19 period started, we expanded it with the addition of several new features in order to support the handling of patients infected with the new virus.Results: This system has handled 112,414 cases during the last 25 months out of which 4,254 were Covid-19 cases. These cases include the transfer of patients from their house to the reference hospital, or the transfer of critical patients from the reference hospital to another hospital with an intensive care unit or transfer of patients from one hospital to another one for other reasons, like the number of admissions.Conclusion: The main purpose of this study was to create an electronic system (eEmergency system) in order to support, improve, and help the procedure of handling emergency calls. The main components and the architecture of this system are outlined in this paper. This system is being successfully used for 25 months and has been a useful tool from the beginning of the pandemic period of Covid-19.
Green Strategy–Based Synthesis of Silver Nanoparticles for Antibacterial Applications
Authors: Ssekatawa Kenneth , Byarugaba Denis K. , Kato Charles D. , Wampande Eddie M. , Ejobi Francis , Nakavuma Jesca L. , Maaza Malik , Sackey Juliet , Nxumalo Edward , Kirabira John Baptist 
Published: August 2021

Antibiotics have been the nucleus of chemotherapy since their discovery and introduction into the healthcare system in the 1940s. They are routinely used to treat bacterial infections and to prevent infections in patients with compromised immune systems and enhancing growth in livestock. However, resistance to last-resort antibiotics used in the treatment of multidrug-resistant infections has been reported worldwide. Therefore, this study aimed to evaluate green synthesized nanomaterials such as silver nanoparticles (AgNPs) as alternatives to antibiotics. UV-vis spectroscopy surface plasmon resonance peaks for AgNPs were obtained between 417 and 475 nm. An X-ray diffraction analysis generated four peaks for bothPrunus africanaextract (PAE) andCamellia sinensisextract (CSE) biosynthesized AgNPs positioned at 2θ angles of 38.2°, 44.4°, 64.5°, and 77.4° corresponding to crystal planes (111), (200), (220), and (311), respectively. A dynamic light-scattering analysis registered the mean zeta potential of +6.3 mV and +0.9 mV for PAE and CSE biosynthesized nanoparticles, respectively. Fourier transform infrared spectroscopy spectra exhibited bands corresponding to different organic functional groups confirming the capping of AgNPs by PAE and CSE phytochemicals. Field emission scanning electron microscopy imaging showed that AgNPs were spherical with average size distribution ranging from 10 to 19 nm. Biosynthesized AgNPs exhibited maximum growth inhibitory zones of 21 mm with minimum inhibitory concentration and minimum bactericidal concentration of 125 and 250 μg/ml, respectively, against carbapenem-resistant bacteria.