bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Study on Relationship of Hounsfield Units Value on Non-contrast Computer Tomography and Recanalization of Intravenous Thrombolysis
Authors: Wang Zhen , Song Kangping , Xu Wei , He Guohua , Feng Tieqiao , Liu Yan , Xu Guilan , Hu Jue , Wang Te , Xiao Hui , Tang Jiansheng , Zhou Junjie , Song Zhi 
Published: November 2021

Objective:
The objective of this study is to determine whether the administration of intravenous
alteplase would be beneficial or futile to patients with acute ischemic stroke caused by
large vessel occlusion (LVO) before endovascular treatment (EVT) and determine the relationship
between Hounsfield units (HU) in non-contrast computed tomography (NCCT) and recanalization
by alteplase.

Methods:
We performed a retrospective analysis of patients with acute ischemic stroke caused by
LVO who received intravenous thrombolysis (IVT) or followed by EVT at our center during
November 2016 and October 2020. The clinical characteristics and imaging features of patients
who achieved recanalization after IVT, and those who did not, were compared.

Results:
Forty-three eligible patients were enrolled; 12 achieved recanalization by IVT. Baseline
clinical characteristics did not differ between patients of the recanalization and non-recanalization
groups. HU in the NCCT were estimated and statistically significant maximum and mean values of
the ipsilateral middle cerebral artery (MCA) were found between the groups (P< 0.05). The results
hint that patients in the non-recanalization group have a higher rHU and δHU value of the ipsilateral
MCA compared with recanalization group (P< 0.05). With regards to the receiver operator characteristic
(ROC) curve, we demonstrated that a high HU value of the ipsilateral MCA could be a
predictor for non-recanalization by IVT.

Conclusion:
Patients suffering LVO stroke are less likely to obtain recanalization by IVT with a
high HU value of the ipsilateral MCA. It is feasible to screen patients with LVO using HU for direct
EVT.
Review on Methods Used to Determine Antioxidant Activity of Origanum majorana
Authors: Tripathy Bimala , Mohapatra Gyanendra Narayan , Kumar B.V.V. Ravi , Chowdhury Bimalendu , Das Rajaram 
Published: November 2021

Background:
The presence of free radicals in the human body is harmful, which may
induce many diseases like cardiovascular, diabetes, cancer, inflammation, neurodegenerative disorder,
atherosclerosis, cataract, etc. Antioxidants can balance the effect of free radicals. Antioxidant-
rich herbs have been identified for the preparation of drugs that can be administered to neutralize
the free radicals. In the present context, the selected medicinal plant is “Origanum majorana”
(Family- Lamiaceae) widely known as Marwa in the Indian sub-continent. As the medical
professionals show their desire towards composite or lateral treatment, the application of drugs
with herbal origin has gained its importance.

Objective:
This review presents various in vitro and in vivo methods used in the antioxidant activity
study of O. majorana and highlights its efficacy in reducing the oxidative stress.

Methods:
Many reliable sources like Research gate, PubMed, Science Direct, Google scholar,
Wiley online library, and books have been referred to collect all information regarding the antioxidant
activity of the selected plant.

Results:
Several methods have been used to determine the antioxidant activity of O. majorana,
such as superoxide radical scavenging, ferric ion reducing antioxidant potency, thiobarbituric acid
reactive substances, hydrogen peroxide scavenging, hydroxyl radical scavenging, lipid peroxidation
inhibition, etc. The selected plant contains many phytoconstituents such as gallic acid, ferulic
acid, apigenin, catechin, rutin, quercetin, luteolin, linolenic acid, β-sitosterol, and essential oils,
which may be responsible for antioxidant activity.

Conclusions:
The review article provides information for investigating and developing new antioxidant
methods and major phytoconstituents from O. majorana for better therapy of oxidative
stress-mediated complications.
The Influence of Wuzhi Capsule on the Pharmacokinetics of Cyclophosphamide
Authors: Chen Wanyi , Chen Lu , Ji Ning , Zhang Min 
Published: November 2021

Background:
Cyclophosphamide is approved for the treatment of a variety of tumors,
yet the use of cyclophosphamide is limited by kidney and liver toxicity. In the clinic, the Wuzhi
capsule is approved to attenuate cyclophosphamide toxicity in the kidney and liver.

Objective:
We aimed to investigate the effects of the principal ingredients of Wuzhi capsule,
schisandrin A (SIA) and schisantherin A (STA), on the pharmacokinetics of cyclophosphamide.

Methods:
The essential pharmacokinetic data and physicochemical parameters of SIA, STA, and
cyclophosphamide were collected. Physiologically based pharmacokinetic (PBPK) models of SIA,
STA, and cyclophosphamide were built in Simcyp Simulator and verified using published clinical
pharmacokinetic data. The verified PBPK models were used to predict potential herb-drug interactions
(HDIs) between cyclophosphamide and SIA and STA in cancer patients.

Results:
The area under the plasma concentration–time curve (AUC) of cyclophosphamide was increased
by 18% and 1% when co-administered with STA and SIA at a single dose, respectively,
and increased by 301% and 29% when co-administered with STA and SIA at multiple doses, respectively.
The maximum concentration (Cmax) of cyclophosphamide was increased by 75% and
7% when co-administered with STA and SIA at multiple doses, respectively.

Conclusion:
The AUC and Cmax of cyclophosphamide were increased when cyclophosphamide was
combined with the Wuzhi capsule, compared to cyclophosphamide alone. Our study shows that the
adverse drug reactions and toxicity of cyclophosphamide should be closely monitored and an effective
dosage adjustment of cyclophosphamide may need to be considered when co-administered
with the Wuzhi capsule.
Molecular and Biochemical Pathways Encompassing Diabetes Mellitus
and Dementia
Authors: Behl Tapan , Arora Arpita , Sehgal Aayush , Singh Sukhbir , Sharma Neelam , Bhatia Saurabh , Al-Harrasi Ahmed , Bungau Simona , Mostafavi Ebrahim 
Published: November 2021

Abstract:
Diabetes mellitus is a major metabolic disorder that has now emerged as an epidemic,
and it affects the brain through an array of pathways. Patients with diabetes mellitus can develop
pathological changes in the brain, which eventually take the shape of mild cognitive impairment,
which later progresses to Alzheimer’s disease. A number of preclinical and clinical studies have demonstrated
this fact, and molecular pathways, such as amyloidogenesis, oxidative stress, inflammation,
and impaired insulin signaling, are found to be identical in diabetes mellitus and dementia.
However, the critical player involved in the vicious cycle of diabetes mellitus and dementia is insulin,
whose signaling, when impaired in diabetes mellitus (both type 1 and 2), leads to a decline in
cognition, although other pathways are also essential contributors. Moreover, it is not only the case
that patients with diabetes mellitus indicate cognitive decline at a later stage, but many patients
with Alzheimer’s disease also reflect symptoms of diabetes mellitus, thus creating a vicious cycle
inculcating a web of complex molecular mechanisms and hence categorizing Alzheimer’s disease
as ‘brain diabetes.’ Thus, it is practical to suggest that anti-diabetic drugs are beneficial in
Alzheimer’s disease. However, only smaller trials have showcased positive outcomes mainly because
of the late onset of therapy. Therefore, it is extremely important to develop more of such
molecules that target insulin in patients with dementia along with such methods that diagnose impaired
insulin signaling and the associated cognitive decline so that early therapy may be initiated
and the progression of the disease can be prevented.
Hydrothermal Synthesis and Photocatalytic Performance of Barium
Carbonate/Tin Dioxide Nanoparticles
Authors: Huang J.F. , Tao F.H. , Yu C.H. , Mao Y.J. , Xue Z.Y. , Wang M.C. , Fan C.G. , Pei L.Z. 
Published: November 2021

Background:
Crystal violet dye is stable and difficult to be biodegraded owing to the existence
of the multiple aromatic rings of the crystal violet molecules. Removing crystal violet dye from
the wastewater is a major challenge.

Objective:
The aim of the research is to synthesize barium carbonate/tin dioxide nanoparticles and investigate
the photocatalytic performance for the degradation of crystal violet.

Methods:
Barium carbonate/tin dioxide nanoparticles were synthesized via a facile hydrothermal route
without any surfactants. The crystal structure, micro-morphology, size and optical performance of the
barium carbonate/tin dioxide nanoparticles were investigated by powder X-ray diffraction, scanning
electron microscopy, transmission electron microscopy and solid ultraviolet-visible diffuse reflectance
spectrum.

Results :
The size of the barium carbonate/tin dioxide nanoparticles is 20 nm to 200 nm with the band
gap of 3.71 eV. The photocatalytic activity of the barium carbonate/tin dioxide nanoparticles was
measured by the photocatalytic degradation of crystal violet. The crystal violet degradation efficiency
reaches 92.1% with the ultraviolet-visible irradiation time of 8 h using 10 mg barium carbonate/tin dioxide
nanoparticles. The crystal violet degradation ratio increases to 96.1% when the dosage of the barium
carbonate/tin dioxide nanoparticles increases to 20 mg/10 mL crystal violet dye solution. Active
species capture photocatalytic experiments showed that the holes, hydroxyl radicals and superoxide ion
radicals are the main active species. Reusability experiments displayed that the barium carbonate/tin
dioxide nanoparticles are stable for the crystal violet dye degradation.

Conclusion:
The barium carbonate/tin dioxide nanoparticles show good photocatalytic performance
toward crystal violet under ultraviolet light irradiation.
ON THE ASSOCIATION OF IRANIAN EFL TEACHER’S IDENTITY STYLE, RELIGIOUS IDENTITY, AND IDENTITY COMMITMENT
Authors: ALIAKBARI MOHAMMAD , GHASEMI FIAN 
Published: November 2021

The purpose of the present study was to investigate the relationship among EFL teacher’s identity style, religious identity, and identity commitment. The data was collected from 88 EFL teachers teaching at different English language learning institutes in Ilam province- Iran. Two questionnaires were used, including Dollinger’s (2001) Brief Religiosity Scale (BRS-6) and Berzonsky’s (1992) Identity Style Inventory, the revised version (ISI3). Results suggested that EFL teacher’s identity style and their commitment were positively correlated (r = 0.350). There was also a significant positive correlation between EFL teacher’s religious identity and their commitment (r = 0.312). A significant positive correlation was also found between EFL teacher’s identity style and religious identity (r = 0.367). The results of one-way ANOVA indicated that there was a statistically significant difference in identity style scores, identity commitment scores, and religiosity scores for four groups. The results of independent t-test analysis indicated that there was no significant difference in identity style, identity commitment, and the religiosity scores of the two groups of participants. Finally, the implications and limitations of the study were also discussed.
PEACOCK MODEL PEDAGOGY: INTERVENTION AND INNOVATIVE CATALYST IN THE NEW NORMAL PERSPECTIVE OF TEACHING AND LEARNING
Authors: MALLILLIN LEOVIGILDO LITO D. , LAUREL REGILITO D. , ARROYO PILIPINAS AMERICA C. , MALLILLIN JOCELYN B. 
Published: November 2021

The study aims to analyze and identify how peacock model pedagogy improves the intervention and innovation catalyst in the new normal perspective of teaching and learning among the respondents. The study employs both a descriptive quantitative and qualitative research approach and design because it is used in analysing the intervention and innovative catalyst in the new normal perspective of teaching and learning. Purposive sampling is utilized in gathering the sample size of the study. It is a selection of intentional formats based on the concept that elucidates the specific theme or phenomenon of the study. This study comprised thirty six (36) respondents. Results show that students are actively participating and developing quality of leadership and initiative and are actively participating through exchange of ideas and interactions in the peacock model pedagogy on innovation of teaching and learning, participation, with a weighted mean of 4.06 or Agree which shows that students are actively participating and developing quality of leadership and initiative and are participating actively through exchange of ideas and interactions, questioning and experimentation, with a weighted mean of 3.66 or Agree which shows that students are able to frame learning related questions and inquisitive lessons for discussion and are able to frame learning related questions but have difficulties in exploring to answer the question raised among them, empathy and cooperation, with a weighted mean of 3.75 or Agree which shows that students are empathetic towards both the known and unknown persons in the pedagogy of learning in the new normal and are actively empathetic towards the known but only sympathetic towards the unknown process of learning, aesthetic and creative expression of knowledge, with a weighted mean of 3.75 or Agree which shows that students are aesthetic and creative in their new normal learning perspective pedagogy and are aesthetic and creative in their online classes as part of their innovative learning perspective. Findings show that there is a significant difference in the peacock model pedagogy that improves the intervention and innovation catalyst in the new normal perspective of teaching and learning as observed by the respondents.
Solution-focused Brief Counseling Guidebook: Theoretical Validity and Effectiveness in Reducing Student’s Social Anxiety
Authors: Purwani Wayan , Suranata Kadek , Gading I Ketut 
Published: November 2021

Social anxiety is one of the psychological problems faced by most of students. Several research findings have revealed negative effects that arise due to the high level of social anxiety experienced by students. Based on this phenomenon, schools play a major role in efforts to minimize the level of social anxiety experienced by students through optimizing guidance and counseling services. This research and development aim at testing the acceptability and effectiveness a solution-focused brief counseling guidebook to minimize students' social anxiety. The development procedure using 4D steps, such as, define, design, develop, and desimination of the product. The amount five judgment involve to validating the contents of guidebook. For the piloting, one group pretest-post test experimental procedure involve 15 junior high school students. The data analysis for judgments results show that the counseling guidebook developed in this study has a special content validity index (CVI). Based on the results of the piloting study, counseling guidebook a solution-focused brief counseling guidebook with the miracle question technique was effective in reducing students' social anxiety. The results of this study contribute to the optimization of guidance and counseling services in schools.
Hubungan Forgiveness dan Psychological Well-Being pada Mahasiswa yang Pernah Mengalami Putus Cinta
Authors: Tacasily Yanastasia Olivia Mahole 
Published: November 2021

Abstract: This study aims to identify the correlation between forgiveness and psychological well-being of college students who have experienced a breakup. This research is a quantitative correlational. The instruments that used in this study are TRIM-18 scale (Transgression Recated Interpersonal Motivation Scale) developed by McCullough to measure forgiveness, and Ryff's Psychological Well-Being Scale developed by Ryff to measure psychological well-being. The subjects in this study were 79 students from Faculty of Psychology, Satya Wacana Christian University Psychology who were obtained using snowball sampling. The data analysis technique used the Pearson correlation test. The results showed the correlation coefficient r = 0.206 with a significance value of 0.034 (p< 0.05), thus indicating that there is positive correlation between forgiveness and psychological well-being in students who have experienced a breakup. This means that the higher the forgiveness, the higher psychological well-being and vice versa.Keywords: forgiveness, psychological well-being, college student, breakup. Indonesian Abstract: Penelitian ini bertujuan untuk mengetahui hubungan forgiveness dan psychological well-being pada mahasiswa yang pernah mengalami putus cinta. Penelitian ini menggunakan pendekatan kuantitatif dan jenis penelitian yang digunakan adalah korelasional. Teknik pengumpulan data dalam penelitian ini menggunakan dua skala, yaitu TRIM-18 (Transgression Related Interpersonal Motivation Scale) yang dikembangkan oleh McCullough untuk mengukur forgiveness, dan Ryff’s Psychological Well-Being Scale yang dikembangkan oleh Ryff untuk mengukur psychological well-being. Subjek dalam penelitian ini adalah 79 orang mahasiswa Psikologi Universitas Kristen Satya Wacana yang diperoleh menggunakan snowball sampling. Teknik analisis data yang digunakan dalam penelitian ini adalah uji korelasi Pearson. Hasil penelitian menunjukkan koefisien korelasi sebesar r= 0.206 dengan nilai signifikansi sebesar 0.034 (p<0.05). Hasil tersebut menandakan bahwa terdapat hubungan positif antara forgiveness dan psychological well-being pada mahasiswa yang pernah mengalami putus cinta. Hal ini berarti bahwa semakin tinggi forgiveness, maka semakin tinggi psychological well-being begitu pun sebaliknya. Kata kunci: forgiveness, psychological well being, mahasiswa¸ putus cinta
Regulasi Emosi pada Remaja Korban Perceraian yang Mengalami Perilaku Abuse oleh Orang Tua
Authors: Dybah Fara 
Published: November 2021

Abstract: This study discusses about child victims of divorce whose parents that also experienced abuse from their parents and explain how children regulate their emotions about the uncomfortable treatment they feel. The result showed that the participants had a good emotional regulation. Children with good emotional regulation will have the ability to see situations and be able to change as assessment about situations positively and will cause a positive emotional reaction too. But, if someone's lack of ability to regulate their emotions will cause individual attitude that not assertive. This study uses qualitative research methods to figure out the phenomena from subjects holistically and means of words and language. Keywords: Divorce, abuse, emotional regulation.
Psychological Well-Being pada Pengungsi Pencari Suaka yang Tinggal di Negara Transit
Authors: Wati Rahma , Venny Venny , Tantama Yudy Sastra , Dwi Putra Achmad Irvan 
Published: November 2021

Abstract: The number of refugees and asylum seekers in Indonesia continues to increase. During the process of finding a solution, many things happen in their lives that have an impact on psychology. This study focuses on the psychological well-being of refugees seeking asylum in transit countries. This study used qualitative research methods. A purposive sampling technique was conducted to determine six subjects, consisting of groups of unaccompanied adolescents, heads of families, and single mothers. Data obtained through interview and observation methods. The reason the researchers used this research technique was to dig deeper into the psychological well-being aspects of refugees seeking asylum in transit countries. The results showed that age and positive social support greatly affected the psychological well-being of the unaccompanied adolescent group and the head of the family, while the lack of social support for the single mother group subject made the subject experience low psychological well-being. Indonesian Abstract. Jumlah pengungsi dan pencari suaka di Indonesia terus meningkat. Selama proses penemuan solusi, banyak hal terjadi dalam hidup mereka yang berdampak pada dampak psikologis. Penelitian ini berfokus pada kesejahteraan psikologis pengungsi pencari suaka di negara transit. Penelitian ini menggunakan metode penelitian kualitatif. Teknik purposive sampling dilakukan untuk menentukan enam subjek, yang terdiri dari kelompok remaja tanpa pendamping, kepala keluarga, dan ibu tunggal. Data diperoleh melalui metode wawancara dan observasi. Alasan peneliti menggunakan teknik penelitian ini adalah untuk menggali lebih dalam aspek kesejahteraan psikologis pengungsi pencari suaka di negara transit. Hasil penelitian menunjukkan bahwa usia dan dukungan sosial yang positif sangat mempengaruhi kesejahteraan psikologis subjek kelompok remaja tanpa pendamping dan kepala keluarga, sedangkan kurangnya dukungan sosial pada subjek kelompok single mother membuat subjek mengalami kesejahteraan psikologis. rendah.
The Awareness of Sharia Financial Literacy in The Quarter-Life Phase
Authors: Rahmatia Alfina , Saputra Arief Dwi 
Published: November 2021

Nowadays, there are enormous challenges toward this era, especially the young generation between 20 and first 30 years old who will face a quarter-life crisis phase in which one of the causes is literate or not literate to finance. The grand objective of this research is to analyze gender, income per month, and marital status toward the awareness level to sharia financial literacy in the quarter-life crisis phase for IAIN Palangka Raya Alumni on 2010-2015. Primary data applied in this study are compiled from questionnaires and interviews with mixed methods. This research uses multiple regression with SPSS application, while the interview data uses descriptive analysis. The result reveals that gender and income per month have no significant influence on the awareness level of sharia financial literacy, but marital status has a significant influence on the awareness level of sharia financial literacy for IAIN Palangka Raya Alumni on 2010-2015.
A Review of Solar Still Assessment with Various PCM Materials
Authors: Sen Pradeep , Badgaiyan Prof. Pankaj , Girdhani Prof. Bharat , Daniel Prof. Shamir 
Published: November 2021

Solar distillation purifies water by transferring sun's heat to a simple device. A shallow basin with a glass shield makes up the majority of the system, which is usually referred to as a solar even now. Evaporation takes place when the pool water is heated by the sun. Humidity rises, condenses on the shield, and drips into a drip tray, leaving salts, minerals, as well as the majority of contaminants behind. The oceans, that have a high salinity, are now the only nearly inexhaustible source of water supply.Separating salts from seawater, on the other hand, necessitates a huge amount of energy, that also, when derived from fossil fuels, can be destructive to the environment. As a result, desalination of seawater must be done using environmentally friendly energy sources. PCM which are solar, are widely used to store solar radiation during the day and release it in the evening, in a wide range of solar applications
On Optimization of Manufacturing of a Comparator in Track State to Increase Integration Rate of Elements
Authors: Pankratov E. L. 
Published: November 2021

Abstract
In this paper, an approach to increase integration rate of elements of a comparator in track state was introduced. Framework the approach a het-erostructure with special configuration was consider. Several specific are-as of the heterostructure should be doped by diffusion or ion implantation. Annealing of dopant and/or radiation defects should be optimized.