bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of Axis II psychosocial assessment methods of RDC/TMD and DC/TMD as part of DC/TMD‐FIN phase II validation studies in tertiary care Finnish TMD pain patients
Authors: Hietaharju Maria , Kivimäki Ida , Heikkilä Henriikka , Näpänkangas Ritva , Teerijoki‐Oksa Tuija , Tanner Johanna , Kemppainen Pentti , Tolvanen Mimmi , Suvinen Tuija , Sipilä Kirsi 
Published: September 2021

AbstractBackgroundThe Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) and Diagnostic Criteria for TMD (DC/TMD) include Axis II instruments for psychosocial assessment.ObjectivesThe aims were to compare the Finnish versions of Axis II psychosocial assessment methods of the RDC/TMD and DC/TMD and to study their internal reliability.MethodsThe sample comprised 197 tertiary care referral TMD pain patients. The associations between RDC/TMD [Graded Chronic Pain Scale (GCPS) 1.0, Symptom Check List 90‐revised (SCL‐90R)] and DC/TMD (GCPS 2.0, Patient Health Questionnaire‐9 (PHQ‐9), PHQ‐15) assessment instruments were evaluated using Spearman correlation coefficients, Wilcoxon Signed Rank s, chi‐squared test and gamma statistics. The internal reliability and internal inter‐item consistency of SCL‐90‐R, PHQ‐9, PHQ‐15 and Generalized Anxiety Disorder‐7 (GAD‐7) were evaluated using Cronbach's alpha coefficient values.ResultsThe DC/TMD and RDC/TMD Axis II psychosocial instruments correlated strongly (p < .001). GCPS 1.0 and GCPS 2.0 grades were similarly distributed based on both criteria. The RDC/TMD psychological instruments had a higher tendency to subclassify patients with more severe symptoms of depression and non‐specific physical symptoms compared to DC/TMD. The internal reliability and internal inter‐item consistency were high for the psychological assessment instruments.ConclusionThe Finnish versions of the RDC/TMD and DC/TMD Axis II psychosocial instruments correlated strongly among tertiary care TMD pain patients. Furthermore, the Axis II psychological assessment instruments indicated high validity and internal inter‐item consistency and are applicable in Finnish TMD pain patients as part of other comprehensive specialist level assessments, but further psychometric and cut‐off evaluations are still needed.
Insuring large stakes: A normative and descriptive analysis of households' flood insurance coverage
Authors: Collier Benjamin L. , Schwartz Daniel , Kunreuther Howard C. , Michel‐Kerjan Erwann O. 
Published: September 2021

AbstractHouseholds' insurance coverage against severe losses is central to their financial resilience. Features of the US National Flood Insurance Program offer insights into consumers' coverage over large stakes that are not typically possible in other markets. We examine the coverage limits (the amount of a home's value that is insured) of over 100,000 households. We determine the optimal coverage based on a standard expected utility calibration. This model indicates that consumers should purchase a low limit and retain much of their exposure due to the high premium loads in our sample. Instead, households in the sample typically fully insure their homes, paying premiums well above their contract's expected value. We investigate possible explanations for homeowners' coverage limits and conclude that some combination of industry practices that emphasize fully insuring and probability distortions in decision‐making are likely explanations.
Prediction of tenderness of chicken by using viscoelasticity based on airflow and optical technique
Authors: He Ke , Sun Qinming , Tang Xiuying 
Published: September 2021

AbstractTenderness is an index for evaluating meat quality. A prediction model of tenderness was established based on the chicken deformation, which was determined by a viscoelasticity system combined with airflow and optical technique. Different preprocessing methods were used to preprocess the deformation. The interval variables that represent the viscoelasticity of the chicken in deformation, were screen by synergy interval partial least squares algorithm (Si‐PLS) and moving window partial least squares algorithm (Mw‐PLS). The prediction model was established by principal component regression (PCR) and partial least squares regression (PLSR). The optimum PLSR prediction model was established when Mw‐PLS was used to screen the interval variables of Savitzy‐Golay (S‐G) smoothing data. The correlation coefficient and the root mean square error of the calibration set were 0.965 and 0.874 kg, respectively. The corresponding value of the prediction set was 0.943 and 1.005 kg. This research provides a new method to assess the quality of poultry meat that conducts on airflow and optical techniques.
COVID‐19‐associated subacute invasive pulmonary aspergillosis
Authors: Swain Satish , Ray Animesh , Sarda Radhika , Vyas Surabhi , Singh Gagandeep , Jorwal Pankaj , Kodan Parul , Khanna Puneet , Xess Immaculata , Sinha Sanjeev , Wig Naveet , Trikha Anjan 
Published: September 2021

AbstractBackgroundThough invasive pulmonary aspergillosis is a well known complication of COVID‐19 pneumonia, indolent forms of aspergillosis have been rarely described.MethodsWe prospectively collected the clinico‐radio‐microbiological data of 10 patients of subacute invasive pulmonary aspergillosis (SAIA), who presented to our hospital with recent history of COVID‐19 pneumonia along with cavitary lung disease, positive IgG (against Aspergillus) with or without positive respiratory samples for Aspergillus spp.ResultThe mean age of presentation of SAIA was 50.7 ± 11.8 years. All the patients had recently recovered from severe COVID‐19 illness with a mean duration of 29.2 ± 12 days from COVID‐19 positivity. Cough was the predominant symptom seen in 8/10 (80%) patients followed by haemoptysis. 7/10 (70%) patients were known diabetic. While serum galactomannan was positive in 5/9 patients (55.5%), fungal culture was positive in 2/7 patients (28.5%) and polymerase chain reaction (PCR) for Aspergillus was positive in three patients. Eight (80%) patients presented with a single cavitary lesion; pseudoaneurysm of pulmonary artery was seen in two patients and post‐COVID‐19 changes were seen in all patients. All patients were treated with voriconazole, out of which four (40%) patients died during the follow‐up period.ConclusionSAIA should be considered in the differential diagnosis of cavitating lung lesions in patients with recent history of COVID‐19 in the background of steroid use with or without pre‐existing diabetes.
Phylogenomic analysis points to a South American origin of Manihot and illuminates the primary gene pool of cassava
Authors: Simon Marcelo F. , Mendoza Flores J. Moises , Liu Hsiao‐Lei , Martins Márcio Lacerda Lopes , Drovetski Sergei V. , Przelomska Natalia A. S. , Loiselle Hope , Cavalcanti Taciana B. , Inglis Peter W. , Mueller Natalie G. , Allaby Robin G. , Freitas Fábio de Oliveira , Kistler Logan 
Published: September 2021

Summary

The genus Manihot, with around 120 known species, is native to a wide range of habitats and regions in the tropical and subtropical Americas. Its high species richness and recent diversification only c. 6 million years ago have significantly complicated previous phylogenetic analyses. Several basic elements of Manihot evolutionary history therefore remain unresolved.

Here, we conduct a comprehensive phylogenomic analysis of Manihot, focusing on exhaustive sampling of South American taxa.

We find that two recently described species from northeast Brazil's Atlantic Forest were the earliest to diverge, strongly suggesting a South American common ancestor of Manihot. Ancestral state reconstruction indicates early Manihot diversification in dry forests, with numerous independent episodes of new habitat colonization, including into savannas and rainforests within South America. We identify the closest wild relatives to Manihot esculenta, including the crop cassava, and we quantify extensive wild introgression into the cassava gene pool from at least five wild species, including Manihot glaziovii, a species used widely in breeding programs. Finally, we show that this wild‐to‐crop introgression substantially shapes the mutation load in cassava.

Our findings provide a detailed case study for neotropical evolutionary history in a diverse and widespread group, and a robust phylogenomic framework for future Manihot and cassava research.
Cantil – a new organ or a morphological oddity?
Authors: Bondada Ramesh , Kulaar Dilsher Singh , Siddiqi Imran , Maruthachalam Ravi 
Published: September 2021

SummaryCantil is reported as a new‐found organ specific to the model plant Arabidopsis thaliana that is prominent only in short‐day‐grown wild‐type accessions or long‐day‐grown genetic mutants with delayed vegetative to reproductive transition. Here, we show that cantils (previously known as nubbins) arise as one of the many phenotypic consequences of aneuploidy resulting from chromosome dosage imbalances in Arabidopsis polyaneuploids despite normal reproductive transition in long‐day photoperiods. Without a demonstrated function or adaptive significance, we view cantils as a morphological oddity rather than a separate organ, and as a manifestation of physiological perturbations triggered by genetic and environmental factors. We also note a striking phenotypic resemblance between ‘cantil’ and ‘gynophore’, a floral morphological structure that is naturally present in the allopolyploid Arabidopsis suecica.
Redox‐mediated structural and functional switching of C‐repeat binding factors enhances plant cold tolerance
Authors: Wi Seong Dong , Lee Eun Seon , Park Joung Hun , Chae Ho Byoung , Paeng Seol Ki , Bae Su Bin , Phan Thi Kieu Anh , Kim Woe‐Yeon , Yun Dae‐Jin , Lee Sang Yeol 
Published: September 2021

SummaryC‐repeat binding factors (CBFs) are key cold‐responsive transcription factors that play pleiotropic roles in the cold acclimation, growth, and development of plants. Cold‐sensitive cbf knockout mutants and cold‐tolerant CBF overexpression lines exhibit abnormal phenotypes at warm temperatures, suggesting that CBF activity is precisely regulated, and a critical threshold level must be maintained for proper plant growth under normal conditions. Cold‐inducible CBFs also exist in warm‐climate plants but as inactive disulfide‐bonded oligomers. However, upon translocation to the nucleus under a cold snap, the h2‐isotype of cytosolic thioredoxin (Trx‐h2), reduces the oxidized (inactive) CBF oligomers and the newly synthesized CBF monomers, thus producing reduced (active) CBF monomers. Thus, the redox‐dependent structural switching and functional activation of CBFs protect plants under cold stress.
Shoot and root insect herbivory change the plant rhizosphere microbiome and affects cabbage–insect interactions through plant–soil feedback
Authors: Friman Julia , Karssemeijer Peter N. , Haller Julian , de Kreek Kris , van Loon Joop J.A. , Dicke Marcel 
Published: September 2021

SummaryPlant–soil feedback (PSF) may influence plant–insect interactions. Although plant defense differs between shoot and root tissues, few studies have examined root‐feeding insect herbivores in a PSF context. We examined here how plant growth and resistance against root‐feedingDelia radicumlarvae was influenced by PSF.We conditioned soil with cabbage plants that were infested with herbivores that affectD.radicumthrough plant‐mediated effects: leaf‐feedingPlutella xylostellacaterpillars andBrevicoryne brassicaeaphids, root‐feedingD. radicumlarvae, and/or added rhizobacteriumPseudomonas simiaeWCS417r. We analyzed the rhizosphere microbial community, and in a second set of conspecific plants exposed to conditioned soil, we assessed growth, expression of defense‐related genes, andD. radicumperformance.The rhizosphere microbiome differed mainly between shoot and root herbivory treatments. Addition ofPseudomonas simiaedid not influence rhizosphere microbiome composition. Plant shoot biomass, gene expression, and plant resistance againstD. radicumlarvae was affected by PSF in a treatment‐specific manner. Soil conditioning overall reduced plant shoot biomass,Pseudomonas simiae‐amended soil causing the largest growth reduction.In conclusion, shoot and root insect herbivores alter the rhizosphere microbiome differently, with consequences for growth and resistance of plants subsequently exposed to conditioned soil.
Alterations in subgingival microbiota during full‐fixed appliance orthodontic treatment—A prospective study
Authors: Chen Isaac , Chung Jennifer , Vella Raven , Weinstock George M. , Zhou Yanjiao , Jheon Andrew H. 
Published: September 2021

AbstractBackgroundFull‐fixed appliance orthodontic treatment (commonly called braces) increases plaque accumulation and the risk of gingivitis and periodontitis. However, little consensus exists on changes to subgingival microbiota and specific periodontopathogens during treatment with braces. Prior studies have been hampered by selection biases due to dependence on culture conditions, candidate‐based PCR and shallow sequencing methods.ObjectiveThe objective was to provide the first longitudinal, culture‐free and deep‐sequence profiling of subgingival bacteria in subjects during early stages of full‐fixed orthodontic treatment.MethodsWe performed 16S rRNA next‐generation sequencing (NGS) on 168 subgingival samples collected at 4 distinct mandibular tooth sites per subject before (0 weeks) and during (6 and 12 weeks) orthodontic intervention in 9 experimental and 5 control subjects not undergoing treatment.ResultsOverall, we noted that orthodontic intervention led to increased microbial richness, accompanied by an increased incidence of localized gingivitis/mild periodontitis in subjects requiring orthodontic treatment compared to controls, as well as significant baseline variations in subgingival microbiomes in all subjects. Moreover, we confirmed individual‐ and site‐dependent microbiome variability (in particular, the lingual site harboured higher microbiome diversity than buccal sites) that orthodontic bands may lead to more prolonged shifts in microbial changes compared to brackets, and evidence of adaptive enrichment of consensus bacteria with orthodontic intervention (12 novel, consensus bacterial species were identified).ConclusionOur study, along with evolving global profiling methods and data analyses, builds a strong foundation for further analyses of subgingival microbiomes during full‐fixed orthodontic treatment.
“Cannot intubate, cannot oxygenate”: A novel 2‐operator technique for cannula tracheotomy in an infant animal model—a feasibility study
Authors: Prunty Sarah L. , Heard Andrew M. , Chapman Gordon , Challen Andrew , Vijayasekaran Shyan , von Ungern‐Sternberg Britta S. 
Published: September 2021

AbstractBackgroundEvidence regarding optimal management of the “Cannot Intubate, Cannot Oxygenate” (CICO) scenario in infants is scarce. When inserting a transtracheal cannula for front of neck access direct aspiration to confirm intratracheal location is standard practice. This postmortem “infant airway” animal model study describes a novel technique for cannula tracheotomy.AimsTo compare a novel technique of cannula tracheotomy to an accepted technique to assess success and complication rates.MethodsTwo experienced proceduralists repeatedly performed tracheotomy using an 18‐gauge BD InsyteTM cannula (BD, Franklin Lakes, NJ, USA) in 6 postmortem White New Zealand rabbits. Cannulas were attached either directly to a 5ml syringe (Direct Aspiration) or via a 25 cm length minimum volume extension tubing set (TUTA Healthcare Lidcombe, NSW, Australia) (Indirect Aspiration, 2 operator technique). Each technique was attempted a maximum of 12 times per rabbit with an ENT surgeon assessing success and complication rates endoscopically for each attempt.Results72 tracheotomy attempts were made in total, 36 for each technique. Initial aspiration through the needle was achieved in 93% (97.2% direct versus 89% indirect). Advancement of the cannula and continued aspiration (success) into the trachea occurred in 67% for direct compared with 64% for indirect aspiration. Direct aspiration was associated with higher rates of lateral (10.3% versus 5.6%) and posterior (19.4% versus 13.9%) wall injury compared with the indirect 2‐operator technique.ConclusionCannula tracheotomy in infant‐sized airways is technically difficult and seems frequently associated with tracheal wall injury. The reduced incidence of injury in the indirect group warrants further investigation in preclinical and clinical trials.
Safety risk associated with use of nonsteroidal anti‐inflammatory drugs in Japanese elderly compared with younger patients with osteoarthritis and/or chronic low back pain: A retrospective database study
Authors: Togo Kanae , Ebata Nozomi , Yonemoto Naohiro , Abraham Lucy 
Published: September 2021

AbstractPurposeThis study aimed to assess the safety risks associated with using nonsteroidal anti‐inflammatory drugs (NSAIDs) in elderly patients (≥65 years) compared with younger patients (<65 years) with osteoarthritis (OA) and/or chronic low back pain (CLBP).MethodsA retrospective analysis was conducted on anonymized claims data of patients prescribed NSAIDs for OA and/or CLBP from 2009 to 2018 using hospital‐based administrative database—Medical Data Vision (MDV). The key outcome was the incidence of developing gastrointestinal (GI), renal, and acute myocardial infarction (AMI) that are well‐known events associated with NSAID use.ResultsOf 288,715 patients included, 23.7%, 60.5%, and 15.8% had OA, CLBP, or both, respectively. Elderly patients used non‐oral NSAIDs more frequently than oral NSAIDs (57.8% and 38.7%, respectively), whereas younger patients showed comparable use (50.7% and 52.8%, respectively). The incidence of events per 10,000 person‐years (95% CI) was higher in the elderly than in younger patients: GI, 29.68(27.67–31.68) vs. 16.61(14.60–18.63); renal, 124.77(120.56–128.99) vs. 39.88(36.72–43.03); and AMI, 27.41(25.48–29.35) vs. 10.90(9.27–12.53), respectively. After adjusting for covariates, the increase in risk for these events was seen in patients >70 years compared with younger patients (18–30 years) and was remarkable in patients >80 years with 2‐fold, 10‐fold, and 7‐fold higher risk for developing GI, renal, and AMI events, respectively.ConclusionRisk for developing NSAID‐associated events was higher in the elderly; particularly, renal and AMI events that remarkably increased in patients >80 years. To reduce them, NSAIDs should be prescribed at the lowest effective dose for the shortest duration possible.
Observed physical activity among Latinx and White men and women on a new urban trail
Authors: Kraft Amber N. , Phan Jenny , Jones Kelly , Zenk Shannon N. 
Published: September 2021

AbstractObjectiveDespite efforts to increase physical activity through new green space infrastructure such as trails, disparities in physical activity may persist. The current study compared observed vigorous physical activity (VPA) engagement among White and Latinx men and women on a new urban trail, and whether engagement varied over time.Design, sample, and measuresWe used a modified System for Observing Play and Recreation in Communities (SOPARC) methodology to determine observed race/ethnicity, gender, and physical activity level of trail users (n = 15,109).ResultsLogistic regression analyses revealed the odds of engaging in VPA were lower for Latina women than all other population subgroups (vs. White men: OR 0.19, CI 0.17–0.22; vs. White women: OR 0.48, CI 0.42–0.54, vs. Latino men: OR 0.23, CI 0.19–0.26). VPA engagement by White and Latina women increased across the study years (OR 1.31, CI 1.17–1.46; OR 1.36, CI 1.08–1.71, respectively) but did not differ significantly by year for White and Latino men.ConclusionFuture efforts to address racial/ethnic‐gender disparities in VPA should take an intersectional approach to ensure that the needs of the most vulnerable population subgroups are properly accounted for.
Adverse childhood experiences among previously homeless African American women
Authors: Schmitt Marin , Dressel Anne , Del Carmen Graf Maria , Pittman Belinda , Deal Emily , Krueger Emma , Lopez Alexa A. , Kako Peninnah , Mkandawire‐Valhmu Lucy 
Published: September 2021

AbstractObjectiveTo learn how adverse childhood experiences (ACEs) impacted the life course trajectory of formerly homeless and at‐risk African American women.DesignIntersectionality and life course theory informed this qualitative pilot study, based on an instrumental case study design.SampleForty previously homeless and at‐risk African American women, who were graduates from a long‐term transitional living facility in Milwaukee, Wisconsin.MeasurementsFocus group interviews and one individual interview provided data about participants’ life experiences prior to, during, and following their time at the transitional living facility, which provided supportive wrap‐around services. Interviews were audiotaped, transcribed, and line‐by‐line thematic analysis was conducted to identify themes. Fifteen focus group participants also completed ACE questionnaires.ResultsParticipants reported a high prevalence of multiple ACEs, and three themes were identified: childhood experiences with family conflict, childhood experiences of abuse, and negative coping mechanisms. One‐hundred percent of women had experienced at least one ACE, based on ACE questionnaire responses.ConclusionsACEs affect various parts of patient's lives as adults. For nurses and other healthcare professionals, connecting with community resources provides the opportunity to strategically approach health improvement with wrap‐around resources to improve health outcomes.
Community‐Based Participatory Research partnership with faith‐based organizations to address obesity and glucose control
Authors: Stokes Carmen , Wilson Kristi Jo 
Published: September 2021

AbstractObjectivesTo explore the lived (narrative) experience of obesity and/or diabetes mellitus within focus groups consisting of individuals and community support persons residing in Genesee County, Michigan.DesignQualitative study, using Community‐Based Participatory Research (CBPR) methodology to design and conduct focus group interviews.SampleNineteen participants from faith‐based organizations (FBOs) in Genesee County (74.5% Caucasian, 3.0% Hispanic American).MeasurementsSemi‐structured narrative focus group interviews, using thematic coding and qualitative analysis software (Otter.com).ResultsParticipants from diverse FBOs revealed barriers that prevent them from reaching their weight goals and preventing or controlling diabetes. A shared theme included the concern that providers do not actively inquire about patient concerns at appointments, and they fail to offer practical strategies beyond pharmaceutical interventions.ConclusionFocus group interviews with community residents revealed issues and barriers patients and their support persons face in health care experiences. Utilizing CBPR (methodology) is an opportunity for advanced practice nurses (health care professionals) to co‐create strategies and interventions with the community that can assist them in successfully reaching their weight loss and diabetes prevention goals.