bluuebunny/crossref_metadata_2025_split huggingface dataset:
A cross-sectional study of the mismatch between telecommuting preference and frequency associated with psychological distress among Japanese workers in the COVID-19 pandemic
Authors: Otsuka Souhei , Ishimaru Tomohiro , Nagata Masako , Tateishi Seiichiro , Eguchi Hisashi , Tsuji Mayumi , Ogami Akira , Matsuda Shinya , Fujino Yoshihisa ,   for the CORoNaWork Project
Published: May 2021

AbstractObjectiveTo examine how the mismatch between telecommuting preference and telecommuting frequency was associated with psychological distress during the COVID-19 pandemic.MethodsData from 33,302 workers throughout Japan were obtained using an Internet survey. Among 33,302 participants, 20,395 who telecommuted were included in the analysis. Participants’ telecommuting preference and frequency during the COVID-19 pandemic were determined using a questionnaire. Psychological distress was assessed using Kessler 6 (K6).ResultsAmong participants who did and did not prefer to telecommute, those who telecommuted four or more days per week had an OR of psychological distress of 0.67 (p<0.001) and 1.87 (p=0.001), respectively, compared with those who rarely telecommuted.ConclusionsThe association between telecommuting and psychological distress differs depending on telecommuting preference.
Performance of the TaqMan™ COVID-19 Pooling Kit for detection of SARS-CoV-2 in Asymptomatic and Symptomatic populations at an Institution of Higher Education
Authors: Ganz Troy , Sanderson Sarah , Baush Connor , Mejia Melanie , Gandhi Manoj , Auclair Jared 
Published: May 2021

AbstractClinical evidence for asymptomatic cases of coronavirus disease (COVID-19) has reinforced the significance of effective surveillance testing programs. Quantitative reverse transcriptase polymerase chain reaction (RT-qPCR) assays are considered the ‘gold standard’ for detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA. However, the labor and resource requirements can be prohibitive with respect to large testing volumes associated with the pandemic. Pooled testing algorithms may serve to increase testing capacity with more efficient resource utilization. Due to the lack of carefully curated cohorts, there is limited evidence for the applicability of RT-PCR pooling in asymptomatic COVID-19 cases. In this study, we compared the analytical sensitivity of the TaqMan™ SARS-CoV-2 Pooling Assay to detect one positive sample in a pool of five anterior nare swabs in symptomatic and asymptomatic cohorts at an institute of higher education. Positive pools were deconvoluted and each individual sample was retested using the TaqPath™ COVID-19 Combo Kit. Both assays target the open reading frame (ORF) 1ab, nucleocapsid (N), and spike (S) gene of the strain that originated in Wuhan, Hubei, China. Qualitative results demonstrated absolute agreement between pooled and deconvoluted samples in both cohorts. Independent t-test performed on Ct shifts confirmed an insignificant difference between cohorts with p-values of 0.306 (Orf1ab), 0.147 (N), and 0.052 (S). All negative pools were correctly reported as negative. Thus, pooled PCR testing up to five samples is a valid method for surveillance testing of students and staff in a university setting, especially when the prevalence is expected to be low.
Defensive nymphs in the water-repellent gall of the social aphid Colophina monstrifica (Hemiptera: Aphididae: Eriosomatinae)
Authors: Uematsu Keigo , Aoki Shigeyuki , Yang Man-Miao 
Published: May 2021

AbstractThe aphid Colophina monstrifica forms woolly colonies with sterile soldiers on the secondary host Clematis uncinata in Taiwan. However, the gall or primary-host generation of C. monstrifica has not been found to date. We successfully induced galls of the species on trees of Zelkova serrata through attaching its eggs onto the trees, and also found a few naturally formed galls on another Z. serrata tree. The identity of the aphids was confirmed by examining their morphology and mitochondrial DNA sequences. First- and second-instar nymphs in the galls exhibited attacking behavior toward artificially introduced moth larvae. Observations with a scanning electron microscope revealed that the gall inner surface was densely covered with minute trichomes. This indicates the water repellency of the inner surface, and strongly suggests that young nymphs of C. monstrifica dispose of honeydew globules outside the gall, as known in the congener C. clematis.
Stem cells commit to differentiation following multiple induction events in the Drosophila testis
Authors: Yuen Alice C , Hillion Kenzo-Hugo , Amoyel Marc 
Published: May 2021

AbstractHow and when potential becomes restricted in differentiating stem cell daughters is poorly understood. While it is thought that signals from the niche are actively required to prevent differentiation, another model proposes that stem cells can reversibly transit between multiple states, some of which are primed, but not committed, to differentiate. In the Drosophila testis, somatic cyst stem cells (CySCs) generate cyst cells, which encapsulate the germline to support its development. We find that CySCs are maintained independently of niche self-renewal signals if activity of the PI3K/Tor pathway is inhibited. Conversely, PI3K/Tor is not sufficient alone to drive differentiation, suggesting that it acts to license cells for differentiation. Indeed, we find that the germline is required for differentiation of CySCs in response to PI3K/Tor elevation, indicating that final commitment to differentiation involves several steps and intercellular communication. We propose that CySC daughter cells are plastic, that their fate depends on the availability of neighbouring germ cells, and that PI3K/Tor acts to induce a primed state for CySC daughters to enable coordinated differentiation with the germline.
I broke the glass ceiling, now what? Overview of metaphors to explain gender inequality in organizations
Authors: Grangeiro Rebeca da Rocha , Silva Lucas Emmanuel Nascimento , Esnard Catherine 
Published: May 2021

Purpose
This paper aims to identify and systematically summarize the relevant research on metaphors that are used to explain gender inequalities in the organizational context.

Design/methodology/approach
The researchers conducted a systematic literature review using bibliometric techniques and content analysis.

Findings
The systematic literature review identified a total of 1,269 papers in 688 journals written by 2,441 authors. The first paper was published in 1971 and the publication growth can be observed in the five decades analyzed. The Gender in Management: An International Journal, was the journal that published more papers about this thematic. Michelle Ryan was the most influential researcher regarding the number of papers and citations she had. The content analysis performed with the 27 most influential papers showed 4 research streams (metaphors; gender and leadership; challenges, stereotypes and toxic environment; and gender in the academy). Concerning the metaphors explored in those papers, the glass ceiling is the most prominent. Furthermore, 26 kinds of barriers were identified regarding the challenges that women face to reach positions of power.

Practical implications
The scrutiny of the metaphors and barriers enable access to what is being a hindrance to female progression in the organizational structure. So, this study may instrumentalize organizations and women to improve gender diversity practices in the workplace.

Originality/value
The value of the paper lays in the extensive literature review, using a bibliometric approach and content analysis.
Task performance and occupational health and safety management systems in the garment industry of Bangladesh
Authors: Hoque Imranul , Shahinuzzaman Md. 
Published: May 2021

PurposeThis study investigates the relationship between individual task performance of garment workers and occupational health and safety management systems (OHSMS) in the garment industry of Bangladesh.Design/methodology/approachFollowing a quantitative research approach and using a four-stage cluster sampling technique, data collected from 610 workers of twelve garments supplier factories using a structured questionnaire. Mean, standard deviation, correlation and stepwise multiple regressions performed to understand the relationship between task performance and OHSMS.FindingsThe study results demonstrate that occupational health and safety (OHS) policy, benchmarking, worker participation, OHS training, communication, emergency response, preventive and protective action, monitoring and review are the significant predictors of individual task performance of garment workers; and OHS policy contributes most substantially to the variance of task performance in the garment industry of Bangladesh.Research limitations/implicationsThis study’s findings contribute to operations management, human resources management and the health and safety management literature by demonstrating a link between operational performance, human resources management and OHSMS.Practical implicationsThis study could be beneficial for garment suppliers to understand how effective OHSMS can reduce production costs by increasing worker efficiency.Originality/valueThis is a unique research attempt as it considers the task performance dimension of an individual garment worker from the OHS management perspective.
“Tree against hunger”: potential of enset-based culinary tourism for sustainable development in rural Ethiopia
Authors: Woyesa Tamagn Urgo , Kumar Satinder 
Published: May 2021

PurposeThis is a conceptual study to analyze the potential of enset-based culinary tourism for sustainable rural development and to obtain a place as a niche tourism market in South-Western Ethiopia. It assumed enset agro-biodiversity as the effect of ages of environment, genetic resources and cultural interaction as a distinctive regional image.Design/methodology/approachThis an exploratory paper based on an in-depth interview, field observation and content analysis of documents. By means of in-depth interviews, the researchers managed to gather extended information from community elders and experts in culture and tourism offices selected based on a snowball technique. Besides, it has gone through systematic reviews of about 180 empirical and conceptual articles, books and conference papers with a critical reading of the content, identification of categories, examination and interpretation of ideas, to supplement the in-depth-interview. The thematic analysis applied to identify various ideas, concepts, categories and relationships to produce themes presented under discussion and results.FindingsThe study found enset-based culinary tourism not only improve the local economy and regional image, but also it would enhance conservation of traditional farming system, biodiversity, food heritages, genetic varieties and livestock. It also identified 18 enset food varieties compatible with the principle of balanced diets. Finally, the study advised rural development planners to consider enset-based culinary tourism so that it would revive lost food traditions and consumption patterns, enhance the regional heritage and destination branding.Research limitations/implicationsThe research is a conceptual study that lacked empirical investigation concerning the livelihood impact, gender implication and actual tourist data. Therefore, future research needs to focus on the aforementioned limitations.Practical implicationsThis study addressed SW Ethiopia, which is the primary center of Ensete ventricosum, and argued that enset-based culinary tourism would help to build regional image and obtain a place as a niche rural tourism destination. It would also contribute to the conservation of food heritages, environmentally sustainable farming system, soil conservation, crop diversities and livestock population in addition to producing tourist experience. Moreover, it would encourage the revival of traditional consumption, reinvent lost food traditions and identities.Social implicationsIt was hoped that rural tourism would eventually improve the livelihood and enhance the capability of resilience. It is also expected to maintain the traditional social-economic structure based on the enset farm while fostering cultural development.Originality/valueTo the knowledge of the researchers there is no previous work on enset based-culinary tourism in Ethiopia and probably there is no published culinary tourism paper elsewhere.
Metaheuristic optimization based placement of SVCs with multiple objectives
Authors: Pandian Arun Nambi , Palanivelu Aravindhababu 
Published: May 2021

Purpose
Optimal placement of static VAR compensator (SVC) devices not only improves the voltage profile (VP) but also reduces the active power loss (APL) and enhances the voltage stability (VS) through injecting appropriate VARs at optimal buses. The traditional mathematical methods may not provide global best solution and pose difficulties in handling multi-objective SVC placement (SVCP) problem with complex constraints and forcefully place all the given number of SVCs in the system without assessing their real requirements in enhancing the chosen performances. The purpose of this paper is to formulate the SVCP as a multi-objective optimization problem and solve it using a metaheuristic algorithm for global best solution.

Design/methodology/approach
The proposed SVCP method uses improved harmony search optimization (IHSO) with dissonance-avoiding mechanism for obtaining the global best solution through driving away the solution from the sub-optimal traps. In addition, the method uses a self-adaptive technique for optimally tuning the IHSO parameters and places only the required number of SVCs from the given number of SVCs.

Findings
This paper presents the results of the proposed method for 14, 30 and 57 bus systems and exhibits that the proposed method outperforms the existing SVCP methods in achieving the desired performances.

Originality/value
This paper proposes a new self-adaptive IHSO based SVCP method for optimally placing only the required number of SVCs with a goal of attaining the global best performances.
Successful rechallenge therapy for BRAF/MEK inhibitor‐resistant multiple brain metastases of melanoma
Authors: Fukushima Hidehiko , Iwata Yohei , Saito Kenta , Sugiura Kazumitsu 
Published: May 2021

AbstractCombination therapy with BRAF and MEK inhibitors (BRAFi/MEKi) have dramatically improved prognosis among patients with BRAF‐mutant metastatic melanoma compared with traditional treatment, such as chemotherapy. However, resistance to these targeted agents occurs invariably, thereby limiting their clinical efficacy. Recently, it has been reported that the ligand‐independent phosphorylation of erythropoietin‐producing hepatocellular receptor A2 (EphA2) at Ser‐897 signaling is a driver of BRAF inhibitor resistance in melanoma. A melanoma patient with multiple metastases was treated with dabrafenib plus trametinib therapy and maintained complete remission for more than 2 years. As brain metastasis occurred, we had switched to nivolumab plus ipilimumab therapy. However, new lesions were observed after four cycles of nivolumab plus ipilimumab therapy, she was rechallenged with encorafenib plus binimetinib therapy, and she maintained progression‐free status for more than 7 months. We performed immunohistochemical staining of EphA2, phospho‐EphA2 (p‐EphA2; Ser‐897), and epidermal growth factor receptor (EGFR) of melanoma cells before and/or after dabrafenib and trametinib therapy. Immunohistochemical examination showed higher expression of EphA2, p‐EphA2, and EGFR in the melanoma cells after dabrafenib plus trametinib therapy as compared with that before therapy. Our results may indicate that EphA2, p‐EphA2, and EGFR can be critical factors for resistance and reversible response of BRAFi/MEKi in metastases of melanoma. Our case presents a possible treatment that can help overcome BRAFi/MEKi resistance and improve prognosis of melanoma.
Neurotrophic factor levels in the serum and cerebrospinal fluid of neonates infected with human cytomegalovirus
Authors: Wang Shuang , Zou Fei , Wu Si , Wu Yingying , Yue Yuanyi , Sun Zhengrong 
Published: May 2021

AbstractHuman cytomegalovirus (HCMV) is most likely to damage the central nervous system (CNS) during early embryonic development; however, the early neurodevelopmental abnormalities caused by HCMV infection and the regulation of cytokines remain unclear. Therefore, we investigated neuronal factors in the serum and cerebrospinal fluid (CSF) of newborns infected with HCMV using protein microarray technology with a view to elucidating the changes in specific neuronal factors for use in the development of a reliable index for predicting CNS injury caused by HCMV infection. Serum and CSF were collected from four newborns with HCMV infection and CNS injury (HCMV‐infected group) and from four newborns without CNS infection (control group). A protein microarray containing 29 kinds of CNS‐related cytokines was used to identify differentially expressed neuronal factors in the serum and CSF of the HCMV‐infected and control groups. The levels of the differentially expressed proteins were verified further in 30 CSF samples from an HCMV‐infected group using enzyme‐linkedimmunosorbent assay (ELISA). Between newborns in the HCMV‐infected and control groups, the protein microarray analysis identified three differentially expressed neurotrophic factors in the CSF samples: Acrp30, MMP‐3, and interleukin‐1 alpha (IL‐1α). No differential cytokine expression was seen in the serum. ELISA showed significantly higher expression levels of Acrp30 and MMP‐3 in the CSF of the 30 newborns with HCMV infection and CNS injury than in those in the control group, whereas the expression of IL‐1α was significantly lower. Our results demonstrate that changes in the expression levels of Acrp30, MMP‐3, and IL‐1α in the CSF of newborns infected with HCMV may be related to the pathogenesis of CNS infection.
Research Note: Automated data‐driven alignment of near‐bit and top‐drive vibration sensors for seismic while drilling and beyond
Authors: Egorov Anton , Silvestrov Ilya , Bakulin Andrey , Golikov Pavel 
Published: May 2021

ABSTRACTDownhole near‐bit vibration sensors are used to record the pilot signal for seismic while drilling and identify drilling dysfunctions for drilling optimization. The typical downhole sensor is a memory‐based device with an inexpensive internal clock of limited accuracy that is not synchronized to surface data. Integrating downhole vibrations with other time‐based data such as surface drilling parameters or seismic recordings requires accurate time alignment between all data sets. We present a novel automated two‐step alignment procedure that uses a Global Positioning System‐synchronized top‐drive vibration sensor as a reference. The accuracy of the new method satisfies the most demanding requirements of seismic while drilling. The first step finds the delay time and linear drift using global optimization. The second step estimates nonlinear drift using time‐variant cross‐correlation. Alignment precision of a few seconds after the first step becomes a few milliseconds after the second step, as demanded by seismic‐while‐drilling. The field data example shows that the proposed methodology successfully aligns top‐drive and downhole data using a fully unsynchronized near‐bit vibration data set. After alignment, the near‐bit sensor delivers a usable pilot for seismic‐while‐drilling processing, resulting in better quality correlated seismic data than those obtained with the top‐drive surface pilot.
Coordination of leaf economics traits within the family of the world's fastest growing plants (Lemnaceae)
Authors: Ishizawa Hidehiro , Onoda Yusuke , Kitajima Kaoru , Kuroda Masashi , Inoue Daisuke , Ike Michihiko 
Published: May 2021

Abstract

The duckweed family (Lemnaceae) is a group of free‐floating aquatic plants with bodies consisting of single floating fronds that multiply clonally. Although they are known to have the fastest relative growth rate (RGR) among higher plants, their functional trait coordination in relation to within‐family variation of RGR is poorly understood.

We tested how duckweed species fit within the trait covariation patterns known as the world‐wide leaf economics spectrum (LES). To this end, several functional traits were evaluated for 15 duckweed species, and their covariation patterns were compared with those in the global database of plant functional traits.

As a group, duckweeds exhibited the most acquisitive suite of traits, with extremely small leaf mass per area (LMA), short life span and high mass‐based photosynthetic rate (Amass). These LES traits showed a tight correlation with RGR, corroborating our hypothesis that acquisitive leaf resource economics underpins their extremely high RGR. However, unlike other higher plants, LMA showed weak association with leaf life span and Amass within duckweed family. We also found a unique positive correlation between duckweed LMA and area‐based photosynthetic rates, an indication that their LMA represents different functional significance compared to typical higher plants.

Synthesis. Duckweeds, the world's fastest growing plants, mostly follow the world‐wide LES and locate at its extreme end. The slight deviation from the LES highlights that duckweeds experience some physical and chemical constraints not faced by other higher plants.
Properties of transglutaminase‐induced myofibrillar/wheat gluten gels
Authors: Ouyang Yuanyuan , Xu Jingjing , Ji Fuyun , Tan Mengna , Luo Shuizhong , Zhong Xiyang , Zheng Zhi 
Published: May 2021

AbstractGelation properties of myofibrillar protein (MP)/wheat gluten (WG) induced by glutamine transaminase (TGase) were studied. Results showed that the inclusion of transglutaminase increased the gel strength, water‐holding capacity (WHC), and nonfreezable water (Wnf) of MP/WG mixture. Circular dichroism (CD) analysis showed that the β‐sheet and random coil content of the MP/WG treated with TGase addition increased by 12.1% and 3.7%, while the α‐helix and β‐turn content decreased by 14.2% and 1.8%. Rheological measurements showed that TGase induced higher energy storage modulus value during the MP/WG gel heating‐cooling cycle. the hydrogen bond and hydrophobic interaction content of the MP/WG gels increased by 80 and 120 ug/L, and the disulfide bond decreased by 200 ug/L, with TGase addition was increased from 0 to 120 U/g protein. Scanning electron microscope (SEM) showed that MP/WG gel with TGase had uniform and dense network structure.Practical ApplicationThe properties of myofibrillar/wheat gluten gel induced by TGase crosslinking was studied. The gel structure and water holding capacity of MP/WG were improved by the cross‐linking of TGase. The study of the gel properties of MP/WG induced by TGase crosslinking also can provide a theoretical basis for analyzing the effect of TGase on the application of gluten protein in complex meat emulsion system.