bluuebunny/crossref_metadata_2025_split huggingface dataset:
Amorpha-4,11-diene synthase: a key enzyme in artemisinin biosynthesis and engineering
Authors: Huang Jin Quan , Fang Xin 
Published: July 2021

AbstractAmorpha-4,11-diene synthase (ADS) catalyzes the first committed step in the artemisinin biosynthetic pathway, which is the first catalytic reaction enzymatically and genetically characterized in artemisinin biosynthesis. The advent of ADS in Artemisia annua is considered crucial for the emergence of the specialized artemisinin biosynthetic pathway in the species. Microbial production of amorpha-4,11-diene is a breakthrough in metabolic engineering and synthetic biology. Recently, numerous new techniques have been used in ADS engineering; for example, assessing the substrate promiscuity of ADS to chemoenzymatically produce artemisinin. In this review, we discuss the discovery and catalytic mechanism of ADS, its application in metabolic engineering and synthetic biology, as well as the role of sesquiterpene synthases in the evolutionary origin of artemisinin.
A Single-Session Combined Cognitive Bias Modification Training Targeting Attention and Interpretation Biases in Aggression
Authors: AlMoghrabi Nouran , Franken Ingmar H.A. , Mayer Birgit , Huijding Jorg 
Published: July 2021

AbstractExperimental studies applying cognitive bias modification of attention (CBM-A) and interpretation (CBM-I) to reduce aggression have examined the effect of modifying each cognitive bias in isolation. In order to maximise the potential impact on both biases and symptom reduction, we examined whether a combined bias training procedure targeting both attention and interpretation biases (CBM-AI) in combination would be more effective than targeting interpretation bias (CBM-I) alone. University students (17–35 years) were randomly assigned to either a single session of CBM-AI training (n = 40), CBM-I training (n = 40), or a control condition (n = 40). Contrary to our expectations, participants showed an increase in adaptive attention and pro-social interpretation bias in all training conditions. Additionally, in none of the conditions, we found a significant change on self-reported or behavioural aggression. These findings suggest: (1) that the combined training did not have added effect over single interpretation bias training, (2) that training interpretation bias may lead to changes in attention bias, (3) that elements of the control condition unexpectedly, but interestingly, also affected attention and interpretation biases, and (4) single-session CBM procedures do not produce robust effects on self-report or behavioural measures of aggression in unselected samples.
Assessing the risk of plant species invasion under different climate change scenarios in California
Authors: Renteria Jorge L. , Darin Gina M. Skurka , Grosholz Edwin D. 
Published: July 2021

AbstractUsing species distribution models (SDMs), we predicted the distribution of 170 plant species under different climatic scenarios (current and future climatic conditions) and used this information to create invasion risk maps to identify potential invasion hot spots in California. The risk of invasion by individual species was also assessed using species’ predicted area in combination with some biological traits associated with invasiveness (growth form, reproduction mechanisms, and age of maturity). A higher number of species would find suitable climatic conditions along the coast; the Central Western (CW) and South Western (SW) were ecoregions where a higher number of species were predicted. Overall, hot spots of species distribution were similar under current and future climatic conditions; however, individual species’ predicted area (increase or decrease) was variable depending on the climate change scenario and the greenhouse gas emission. Out of the 170 species assessed, 22% ranked as high-risk species, with herbs, grasses, and vines accounting for 78% within this risk class, and a high proportion (67%) of Asteraceae species ranked as high risk. This study suggests that current climatic conditions of the central and south coastal regions of California would be considered as hot spots of new invasions, and for some species this risk might increase with hotter and drier future climatic conditions.
Detecting true relationships in time series data with different orders of integration
Authors: Enns Peter K. , Moehlecke Carolina , Wlezien Christopher 
Published: July 2021

AbstractIt is fairly well-known that proper time series analysis requires that estimated equations be balanced. Numerous scholars mistake this to mean that one cannot mix orders of integration. Previous studies have clarified the distinction between equation balance and having different orders of integration, and shown that mixing orders of integration does not increase the risk of type I error when using the general error correction/autoregressive distributed lag (GECM/ADL) models, that is, so long as equations are balanced (and other modeling assumptions are met). This paper builds on that research to assess the consequences for type II error when employing those models. Specifically, we consider cases where a true relationship exists, the left- and right-hand sides of the equation mix orders of integration, and the equation still is balanced. Using the asymptotic case, we find that the different orders of integration do not preclude identification of the true relationship using the GECM/ADL. We then highlight that estimation is trickier in practice, over finite time, as data sometimes do not reveal the underlying process. But, simulations show that even in these cases, researchers will typically draw accurate inferences as long as they select their models based on the observed characteristics of the data and test to be sure that standard model assumptions are met. We conclude by considering the implications for researchers analyzing or conducting simulations with time series data.
From Retrenchment to Selective Social Policy Expansion: The Politics of Federal Cash Benefits in Canada
Authors: Béland Daniel , Prince Michael J. , Weaver R. Kent 
Published: July 2021

AbstractWhile much has been written about the politics of retrenchment, in a number of advanced industrial societies social policy expansion does occur today, which raises issues about how to study it in a post-retrenchment era. The present article explores the new politics of social policy expansion in Canada. Drawing on the work of Paul Pierson, we use an integrated framework that highlights the interaction of five factors: the availability of fiscal resources; the emergence of new social risks; the intensity and nature of partisan competition; the policy preferences of the main political parties; and the role of political institutions, especially federalism. Empirically, the article studies the politics of federal social policy expansion during the Harper (2006–2015) and Justin Trudeau (2015–) years, with a focus on three policy areas: child benefits (Universal Child Care Benefit and Canada Child Benefit), pensions (Old Age Security and Canada/Quebec Pension Plan) and Employment Insurance.
A preliminary study ofBadimiaVězda (Ramalinaceae) in East Asia
Authors: Wang Wei-Cheng , Sangvichien Ek , Buaruang Kawinat , Jiang Shu-Hua , Wei Tie-Zheng , Wei Jiang-Chun 
Published: July 2021

AbstractThe tropical areas of eastern Asia contain a high diversity of foliicolous lichens, including various species of the genusBadimia.Badimia xanthocampylidiaW. C. Wang & J. C. Wei is described from tropical rainforests in southern China and Thailand based on morphology, chemistry, and combined mtSSU, ITS and nrLSU sequences. It is characterized by a pale green thallus with yellow verrucae and bright yellow campylidia and the presence of isousnic acid. Three other species,B. multiseptataPapong & Lücking,B. pallidula(Kremp.) Vězda andB. polillensis(Vain.) Vězda, are discussed and the genusBadimiais newly reported from China. A worldwide key to currently known species in the genus is presented.
Mary, did you consent?
Authors: Hereth Blake 
Published: July 2021

AbstractThe Christian and Islamic doctrine of thevirgin birthclaim God asexually impregnated the Virgin Mary with Jesus, Mary's impregnation was fully consensual (virgin consent), and God never acts immorally (divine goodness). First, I show that God's actions and Mary's background beliefs undermine her consent by virtue of coercive incentives, Mary's comparative powerlessness, and the generation of moral conflicts. Second, I show that God's non-disclosure of certain reasonably relevant facts undermines Mary's informed consent. Third, I show that a recent attempt by Jack Mulder to rescuevirgin consentfails. Asdivine goodnessandvirgin consentare more central to orthodoxy, Christians and Muslims have powerful reason to rejectvirgin birth.
Social participation and life satisfaction among older adults: diversity of practices and social inequality in Switzerland
Authors: Baeriswyl Marie , Oris Michel 
Published: July 2021

AbstractThis paper examines the associations between social participation and individual life satisfaction among older adults. It specifically considers the diversity of the practices and social inequalities among this population. For analyses, we used a large survey of individuals of 65 years and older conducted in 2011 in Switzerland (N = 2,727). The first set of linear regression analyses examines Diener's Satisfaction with Life Scale and its association with various indicators of social participation. While the second set of logistic regression addresses the issue of social inequalities by evaluating the impacts of gender, age group, region and education on social participation indicators that are significantly associated with the satisfaction with life score. Our results stressed the importance of combining multiple forms of participation for life satisfaction and shows that some forms are particularly meaningful: in particular, the involvement in associations, visitation of family or visitation of friends/acquaintances and church attendance. When inequalities among older adults are considered, having rich and varied social participation, being involved in associations and maintaining private sociability with non-kin appear more elitist. While institutionalised and/or private sociability types of participation appear particularly significant for older adults’ life satisfaction, the most traditional integration forms –i.e.family and religions – are crucial for the more vulnerable. Implications for active ageing was equally discussed as well.
Pathogen spectrum changes of respiratory tract infections in children in Chaoshan area under the influence of COVID-19
Authors: Lin Chuang-Xing , Lian Hao-bin , Lin Guang-Yu , Zhang Dan-gui , Cai Xiao-Ying , Cai Zhi-Wei , Wen Fei-qiu 
Published: July 2021

Abstract
From 24 January 2020 to 18 May 2020, Chaoshan took measures to limit the spread of coronavirus disease 2019 (COVID-19), such as restricting public gatherings, wearing masks and suspending classes. We explored the effects of these measures on the pathogen spectrum of paediatric respiratory tract infections in Chaoshan. Pharyngeal swab samples were collected from 4075 children hospitalised for respiratory tract infection before (May–December 2019) and after (January–August 2020) the COVID-19 outbreak. We used liquid chip technology to analyse 14 respiratory pathogens. The data were used to explore between-group differences, age-related differences and seasonal variations in respiratory pathogens. The number of cases in the outbreak group (1222) was 42.8% of that in the pre-outbreak group (2853). Virus-detection rates were similar in the outbreak (48.3%, 590/1222) and pre-outbreak groups (51.5%, 1468/2853; χ2 = 3.446, P = 0.065), while the bacteria-detection rate was significantly lower in the outbreak group (26.2%, 320/1222) than in the pre-outbreak group (44.1%, 1258/2853; χ2 = 115.621, P < 0.05). With increasing age, the proportions of respiratory syncytial virus (RSV) and cytomegalovirus (CMV) infections decreased, while those of Mycoplasma pneumoniae and adenovirus infections increased. Streptococcus pneumoniae, CMV and rhinovirus infections peaked in autumn and winter, while RSV infections peaked in summer and winter. We found that the proportion of virus-only detection decreased with age, while the proportion of bacteria-only detection increased with age (Table 2). Anti-COVID-19 measures significantly reduced the number of paediatric hospitalisations for respiratory tract infections, significantly altered the pathogen spectrum of such infections and decreased the overall detection rates of 14 common respiratory pathogens. The proportion of bacterial, but not viral, infections decreased.
COMBINATION OF SIGNS IN THE CODICES OF CENTRAL MEXICO: EXAMPLES FROM SACRIFICE AND DISMEMBERMENT REPRESENTATIONS
Authors: Dehouve Danièle 
Published: July 2021

AbstractThe system of communication in use in central Mexico at the time of the Spanish Conquest was made up of signs composed largely of pictorial elements, including glyphs (signs in a script) and graphic representations of the ornaments of the deities. It had a generative character that was expressed mainly in the fact that it combined basic signs to create new meanings. This article deals with the combinations between the following signs: the smoking mirror, the flint, the down ball and the skull, all belonging to the field of sacrifice and dismemberment of the human body. They were associated with each other and created the following codified and conventional combinations: mirror-flint, mirror-down, flint-skull, flint-obsidian, skull-down, and a composite pectoral called anahuatl. This article proposes a typology of these combinations, and sheds light on their meanings and the processes of their construction.
Application of the WeChat platform in midterm follow-up after surgical repair of ventricular septal defects in infants
Authors: Xie Wen-Peng , Liu Jian-Feng , Lei Yu-Qing , Cao Hua , Chen Qiang 
Published: July 2021

AbstractBackground:To explore the feasibility and superiority of applying the WeChat platform in a midterm follow-up of surgical repair for ventricular septal defects in infants.Methods:Eighty-six infants with VSD who underwent surgical repair were divided into an outpatient follow-up group and a WeChat follow-up group. The clinical data, including complications, economic cost, time spent, loss to follow-up rate, and parents’ satisfaction at the 3-month and 1-year follow-ups, were recorded and analysed.Results:There was no significant difference in the incidence of post-operative complications between the two groups. Although the loss to follow-up rate in the WFU group was lower than that of the OFU group, the difference was not statistically significant. The economic cost and time spent in the 3 months and 1 year after discharge in the WFU group were significantly lower than those in the OFU group. One year after discharge, the PSQ-18 score of the WFU group was significantly higher than that of the OFU group.Conclusion:Compared with outpatient follow-up, the WeChat platform at the midterm follow-up after surgical repair of VSDs in infants has the advantages of saving time and economic costs and improves parents’ satisfaction.
CLSM and TIRF images from lignocellulosic materials: garlic skin and agave fibers study
Authors: Hernández-Varela Josué , Chanona-Pérez José , Benavides Héctor Calderón , Cerda Susana Gallegos , Victoriano Lizbeth Gonzalez , Perea Flores María de Jesús , López Maximiliano Campos , Rojas Candelas Liliana Edith , Tamayo Benjamín Arredondo 
Published: July 2021

ABSTRACTFluorescence techniques have been widely used by scientists to reveal valuable information from biological samples, but in food science, small progress is known due to the complexity of the samples. In this study, two different biological samples, garlic skin (GS) and agave fibers (AF), were used to evaluate the techniques of confocal laser scanning microscopy (CLSM) and total internal reflection fluorescence (TIRF) microscopy, to obtain valuable information on the fiber size of the samples. A compositional characterization with calcofluor white in CLSM was achieved, but a superficial characterization of the samples with TIRF was made, evidencing fiber sizes of 398.67 ± 48.47 nm and 677.38 ± 76.88 nm for GS and AF, respectively. This work reveals that only an untreated sample can be used with the two techniques in the same microscope. In addition, it is possible to characterize the sample only using a spatial field of research and which valuable information about the structure of the material is found. This work provides the opportunity to use advanced fluorescence techniques for elucidation of structures shortly before studied with these techniques.
Unfolding the case of returnees: How the European Union and its member States are addressing the return of foreign fighters and their families
Authors: Rigotti Carlota , Barboza Júlia Zomignani 
Published: July 2021

AbstractThe return of foreign fighters and their families to the European Union has mostly been considered a security threat by member States, which consequently adopt repressive measures aimed at providing an immediate, short-term response to this perceived threat. In addition to this strong-arm approach, reintegration strategies have also been used to prevent returnees from falling back into terrorism and to break down barriers of hostility between citizens in the long term. Amidst these different strategies, this paper seeks to identify which methods are most desirable for handling returnees.
Influence of recovery treatments on dicamba-injured soybean
Authors: Dintelmann Brian R. , Farrell Shea T. , Bradley Kevin W. 
Published: July 2021

AbstractNon-dicamba-resistant soybean yield loss resulting from dicamba off-target injury has become an increasing concern for soybean growers in recent years. After off-target dicamba movement occurs onto sensitive soybean, little information is available on tactics that could be used to mitigate the cosmetic or yield losses that may occur. Therefore, a field experiment was conducted in 2017, 2018, and 2019 to determine whether certain recovery treatments of fungicide, plant growth hormone, macro- and micronutrient fertilizer combinations, or weekly irrigation could reduce dicamba injury and/or result in similar yield to soybean that was not injured with dicamba. Simulated drift events of dicamba (5.6 g ae ha−1) were applied to non-dicamba-resistant soybean once they reached the V3 or R2 stages of growth. Recovery treatments were applied approximately 14 d after the simulated drift event. Weekly irrigation was the only recovery treatment that provided appreciable levels of injury reduction or increases in soybean height or yield compared to the dicamba-injured plants. Weekly irrigation following the R2 dicamba injury event resulted in an 1% to 14% increase in soybean yield compared with the dicamba-injured control. All other recovery treatments resulted in soybean yields that were similar to the dicamba-injured control, and similar to or lower than the nontreated control. Results from this study indicate that if soybean have become injured with dicamba, weekly irrigation will help soybean recover some of the yield loss and reduce injury symptoms that resulted from off-target dicamba movement, especially in a year with below average precipitation. However, yield loss will likely not be restored to that of noninjured soybean.
Middle‐Low Latitude Neutral Composition and Temperature Responses to the 20 and 21 November 2003 Superstorm From GUVI Dayside Limb Measurements
Authors: Yu Tingting , Wang Wenbin , Ren Zhipeng , Yue Jia , Yue Xinan , He Maosheng 
Published: July 2021

AbstractTIMED/Global Ultraviolet Imager (GUVI) limb measurements of far‐ultraviolet airglow emission have been used to investigate middle‐low latitude thermospheric composition and neutral temperature responses to the 20 and 21 November 2003 (day of year [DOY] 324 and 325) superstorm. Altitude profiles of O, N2 number densities and temperature, as well as O/N2 column density ratio (∑O/N2), on the storm days along the GUVI limb tracks are compared with those on DOY 323 (quiet time). The storm‐time composition and temperature responses were global and evolved continuously as the storm progressed. Specially, N2 and temperature increased almost globally at all altitudes during the storm and their perturbation structures were similar. The magnitudes of their enhancements both increased with altitude and latitude. The storm‐induced O perturbations decreased in the lower thermosphere but increased in the upper thermosphere. Transition heights of O perturbations from decrease to increase changed with latitude and time. During the storm main and recovery phases, the storm‐induced ∑O/N2 decreases were mostly related to the O depletion in the low‐middle thermosphere, whereas ∑O/N2 increases during the storm were primarily caused by N2 depletion. There was a remarkable hemispheric asymmetry in composition responses as they have different morphologies and lifetime, especially during the storm recovery phase.
Evaluating Auroral Forecasts Against Satellite Observations
Authors: Mooney M. K. , Marsh M. S. , Forsyth C. , Sharpe M. , Hughes T. , Bingham S. , Jackson D. R. , Rae I. J. , Chisham G. 
Published: July 2021

AbstractThe aurora is a readily visible phenomenon of interest to many members of the public. However, the aurora and associated phenomena can also significantly impact communications, ground‐based infrastructure, and high‐altitude radiation exposure. Forecasting the location of the auroral oval is therefore a key component of space weather forecast operations. A version of the OVATION‐Prime 2013 auroral precipitation model (Newell et al., 2014, https://doi.org/10.1002/2014sw001056) was used by the UK Met Office Space Weather Operations Centre (MOSWOC). The operational implementation of the OVATION‐Prime 2013 model at the UK Met Office delivered a 30‐min forecast of the location of the auroral oval and the probability of observing the aurora. Using weather forecast evaluation techniques, we evaluate the ability of the OVATION‐Prime 2013 model forecasts to predict the location and probability of the aurora occurring by comparing the forecasts with auroral boundaries determined from data from the IMAGE satellite between 2000 and 2002. Our analysis shows that the operational model performs well at predicting the location of the auroral oval, with a relative operating characteristic (ROC) score of 0.82. The model performance is reduced in the dayside local time sectors (ROC score = 0.59) and during periods of higher geomagnetic activity (ROC score of 0.55 for Kp = 8). As a probabilistic forecast, OVATION‐Prime 2013 tends to underpredict the occurrence of aurora by a factor of 1.1–6, while probabilities of over 90% are overpredicted.