bluuebunny/crossref_metadata_2025_split huggingface dataset:
Emphysematous myocardial abscess without infective endocarditis
Authors: Park Jino , Seol Sang‐Hoon , Song Yeo‐Jeong , Kim Seunghwan , Kim Dong‐Kie , Kim Ki‐Hun , Kim Doo‐Il , Park Bong Soo 
Published: August 2021

AbstractDiagnosis of myocardial abscess without endocarditis is challenging, and a high index of clinical suspicion is fundamental for diagnosis. It should never be ruled out before TEE. And CT could be a helpful modality in case of emphysematous morphology.
Opium poisoning following self‐medication of radiation‐induced dermatitis with topical use of opium latex traditional extract; a teaching case
Authors: Dehghani Mansoureh , Hosseini Seyyed Morteza , Molkara Sara , Fazilat‐Panah Danial , Mehrpour Omid , Soroosh Davood , Zarei Elham , Welsh James S. , Nematshahi Mohammad , Javadinia Seyed Alireza 
Published: August 2021

AbstractDespite Radiation‐induced dermatitis is a self‐limiting complication, it can be complicated if inappropriate self‐medications have been used such as opium latex traditional extract.
Isolated aplasia cutis congenita: A report of two cases
Authors: Wu Yan , Liu Jun , Luo Qiong 
Published: August 2021

AbstractCongenital skin dysplasia, especially isolated scalp defects, is difficult to detect prenatally. The prognosis for isolated congenital scalp defects is good. Treatment options include conservative treatment and surgery. The choice of treatment depends on the patient's individual circumstances.
Ca[B8O11(OH)4] : Eu2+ – A Highly Efficient Deep Blue‐Emitting Phosphor Prepared by Low‐Temperature Self‐reduction
Authors: Liang Pan , Lian Wen‐Li , Liu Zhi‐Hong 
Published: August 2021

AbstractHighly efficient inorganic phosphors are crucial for solid‐state lighting. In this paper, a new method of low‐temperature self‐reduction was used for preparing a highly efficient deep blue‐emitting phosphor of Ca[B8O11(OH)4] : Eu2+ (CBH : Eu2+). The crystal structure, morphology, chemical state, and photoluminescence (PL) properties of the CBH : Eu2+ phosphor have been investigated. By using the screened hybrid function (HSE06), the band gap (Eg) of CBH was calculated to be 7.48 eV, which is a necessary condition for achieving high quantum yield phosphors. The experiment results show that almost all the added raw materials of Eu3+ can be reduced to Eu2+ in CBH crystal under a non‐reducing atmosphere. The CBH : Eu2+ phosphor shows a broad excitation spectrum centered at 277 and 327 nm in the range of 220 to 400 nm, and a narrow‐band emission spectrum centered at 428 nm in the range of 400 to 500 nm, with a full width at half maximum (fwhm) of 42.35 nm. Under UV radiation, the CBH : 2 %Eu2+ exhibits high photoluminescence quantum yield (PLQY=95.0 %), high external quantum efficiency (EQE=31.1 %), and ultra‐high color purity (97.6 %). The PL intensity of CBH : 2 %Eu2+ remains 62.6 % of the initial intensity at 150 °C. Finally, the white light‐emitting diodes (WLED) fabricated by CBH : 2 %Eu2+, excited by a 365 nm chip, presents outstanding performances with a luminous efficacy (LE) of 13.9 lm/W, a color rendering index (CRI) of 89.4, and a correlated color temperature (CCT) of 5825 K. The above results show that CBH : Eu2+ can be used as a promising blue phosphor for WLED. This new method of low‐temperature self‐reduction can be applied to design and prepare other new types of highly efficient phosphors.
An Adjustable Cleft Based on an 8‐Sulfonamide‐2‐Naphthoic Acid with Oxyanion Hole Geometry
Authors: Garrido‐González José J. , Boya del Teso Irene , Fuentes de Arriba Ángel L. , Sanz Francisca , Martín del Valle Eva M. , Morán Joaquín R. , Alcázar Victoria 
Published: August 2021

AbstractCleft type receptors showing the oxyanion hole motif have been prepared in a straightforward synthesis starting from the commercial 3,7‐dihidroxy‐2‐naphthoic acid. The double H‐bond donor pattern is achieved by the introduction of a sulfonamide group in the C‐8 position of naphthalene and a carboxamide at the C‐2 position. This cleft, for which the geometry resembles that of an oxyanion hole, is able to adjust to different guests, as shown by the analysis of the X‐ray crystal structures of associates with methanol or acetic acid. Combination of hydrogen bonds and charge‐transfer interactions led to further stabilization of the complexes, in which the electron‐rich aromatic ring of the receptor was close in space to the electron‐deficient dinitroaromatic guests. Modelling studies and bidimensional NMR experiments have been carried out to provide additional information.
Pathway‐Dependent Phase Transitions of Supramolecular Self‐assemblies Containing Cationic Amphiphiles with Azobenzene and Disulfide Groups
Authors: Sawada Daichi , Asakura Kouichi , Banno Taisuke 
Published: August 2021

AbstractThere have been several attempts to construct supramolecular chemical systems that mimic the phase transitions in living systems. However, most of these phase transitions are one‐to‐one and induced by one stimulus or chemical; there have been few reports on the pathway‐dependent phase transition of supramolecular self‐assemblies in multi‐step. To induce multistep phase transitions, molecular crystals were prepared that contained a cationic amphiphile bearing azobenzene and disulfide groups. A reducing agent caused the crystals to become vesicles, and adjacent, non‐touching vesicles fused under UV and subsequent visible light. Adding a reducing agent to the worm‐like aggregates that were generated after UV irradiation of the original crystals resulted in the growth of sheet‐like aggregates. 1H NMR and fluorescence anisotropy measurements showed that a series of phase transitions was induced by changes in the phase structures from molecular conversions of the reactive amphiphiles. The multiple pathway‐dependent phase transitions of supramolecular self‐assemblies can provide a methodology for developing new stimuli‐responsive materials that exhibit the desirable properties under specific circumstances from a systems chemistry viewpoint.
Smoking‐induced radiation laryngeal necrosis after definitive radiotherapy alone for T1a glottic squamous cell carcinoma: A case report
Authors: Takagawa Yoshiaki , Izumi Sachiko , Aoki Minoru , Umeda Yuka , Ochiai Kazuto , Kumada Junko , Nakaya Muneo , Kadomatsu Yuichiro , Itagaki Shingo , Kita Midori 
Published: August 2021

AbstractBackgroundWe report the case of a patient with smoking‐induced radiation laryngeal necrosis (RLN) after undergoing definitive radiotherapy (RT) alone for T1a glottic squamous cell carcinoma.CaseThe patient was a 63‐year‐old man who had a history of heavy smoking. He quit smoking when he was diagnosed with glottic squamous cell carcinoma. The RT dose was 63 Gy, delivered in 28 fractions with the three‐dimensional conventional RT technique for the larynx. After RT completion, the initial treatment response was complete response. He then underwent follow‐up examinations. At 13 months after RT, the patient resumed smoking. At 2 months after resuming smoking, he had severe sore throat and hoarseness. Laryngoscopy revealed a large tumor in the glottis. Surgical excision was performed, and the patient was histologically diagnosed with RLN, as late toxicity without cancer recurrence. At 3 weeks postoperatively, the patient had dyspnea, and laryngoscopy revealed total laryngeal paralysis. Thus, he underwent an emergent tracheostomy. The administration of steroids affected RLN, and laryngeal paralysis gradually improved.ConclusionsThis case suggests that smoking may have the potential to induce RLN after RT. Moreover, continuing smoking cessation is significantly important for patients with glottic cancer who receive RT. Rather than leaving smoking cessation up to the patient, it would be necessary for clinicians to actively intervene to help patients continue their effort to quit smoking.
A novel blind medical image watermarking scheme based on Schur triangulation and chaotic sequence
Authors: Soualmi Abdallah , Alti Adel , Laouamer Lamri 
Published: August 2021

AbstractImage watermarking is a potentially effective and powerful solution for multimedia security. It is a technique that plays a fundamental role in protecting copyright, proofing ownership, and helps to authenticate sensitive data. Watermarking can cause a decrease in image quality, especially when it comes to medical images. This could provoke false diagnoses, which can lead to serious consequences on the patient's health. In fact, it becomes necessary to think for new more imperceptible, secure watermarking techniques. To provide such techniques, we proposed a novel blind watermarking scheme for medical images, based on Schur decomposition and chaotic sequence (CS). An efficient chaotic method is applied on the watermark and the cover image to obtain encrypted images divided into subblocks. A decomposition based on Schur is utilized to embed the encrypted watermark bits in the cyphered cover image blocks. The same CS is applied to extract the original watermark. We compared the proposed technique with other watermarking schemes. The experimentation results demonstrate that the suggested method achieving good image fidelity and acceptable robustness.
Designing a methodological framework for modeling and performance forecasting of self‐adaptive cloud systems
Authors: Sliem Mehdi , Salmi Nabila , Ioualalen Malika 
Published: August 2021

AbstractAutonomic computing got an increasing attention during past years in the context of Cloud computing in order to optimize the Cloud systems performance and increase their cost‐effectiveness. In that direction, a broad range of various self‐adaptability strategies have been proposed to overcome uncertainties related to Cloud systems like workload variations, hardware failures and malicious attacks. A special attention in the literature has been paid to resource allocation for cost and performance optimization, and self‐healing for better faut‐tolerance. However, while a lot of progress has been done on these topics, there is still a lack of a standardized methodology, easily reproducible and allowing validation and comparison of a self‐adaptability strategies. This article proposes a methodology allowing to forecast the autonomic Cloud systems performances. The idea is to compare different self‐adaptability approaches at the design stage, and identify the most adequate and optimized configuration. This methodology is based on a new architecture description language and a stochastic Petri nets‐based modeling and simulation approach. We illustrate our methodology in this article through a running example and a set of experiments.
Linear Group 13 E≡E Triple Bonds in E2Li62+
Authors: Cui Zhong‐hua , Liu Yu‐qian , Wang Meng‐hui 
Published: August 2021

AbstractThe triply bonded heavier main‐group compounds have a textbooktrans‐bent geometry, in contrast to a familiar linear form found for the lightest analogues. Strikingly, the unexpected linear group 13 E≡E triple bonds were herein found in theD4h‐symmetry E2Li62+clusters, and they possess a large barrier (>18.0 kcal/mol) towards the dissociation of Li+. The perfectly surrounded Li4motifs and two linear coordinated Li atoms strongly suppress the increasing nonbonded electron density of heavier E atoms, making two degenerate π bonds and one multi‐center σ bond in linear heavier main‐group triple bonds. The surrounding Li6motifs not only creates an effective electronic structure to form a linear E≡E triple bond, but the resulting electrostatic interactions account for the highly stable global E2Li62+clusters.
Green Fabrication Approaches of Lignin Nanoparticles from Different Technical Lignins: A Comparison Study
Authors: Figueiredo Patrícia , Lahtinen Maarit H. , Agustin Melissa B. , de Carvalho Danila Morais , Hirvonen Sami‐Pekka , Penttilä Paavo A. , Mikkonen Kirsi S. 
Published: August 2021

AbstractThe production of lignin nanoparticles (LNPs) has emerged as a way to overcome the highly variable and complex molecular structure of lignin. It can offer morphological control of the lignin polymer, allowing the formation of stable LNP dispersions in aqueous media, while increasing the potential of lignin for high‐value applications. However, the polydispersity and morphology of LNPs varies depending on the lignin grade and preparation method, and a systematic comparison using different technical lignins is lacking. In this study, it was attempted to find a green fabrication method with a distinct solvent fractionation of lignin to prepare LNPs using three different technical lignins as starting polymers: BLN birch lignin (hardwood, BB), alkali Protobind 1000 (grass, PB), and kraft LignoBoost (softwood, LB). For that, three anti‐solvent precipitation approaches to prepare LNPs were systematically compared: 70 % aqueous ethanol, acetone/water (3 : 1) and NaOH as the lignin solvent, and water/aqueous HCl as the anti‐solvent. Among all these methods, the acetone/water (3 : 1) approach allowed production of homogeneous and monodisperse LNPs with a negative surface charge and also spherical and smooth surfaces. Overall, the results revealed that the acetone/water (3 : 1) method was the most effective approach tested to obtain homogenous, small, and spherical LNPs from the three technical lignins. These LNPs exhibited an improved stability at different ionic strengths and a wider pH range compared to the other preparation methods, which can greatly increase their application in many fields, such as pharmaceutical and food sciences.
Equation of state of hydrogen, helium, and solar plasmas
Authors: Ebeling Werner , Reinholz Heidi , Röpke Gerd 
Published: August 2021

AbstractThe equation of state (EOS) for plasmas of the two lightest elements H and He, and mixtures as typical for the plasmas in the sun are calculated. The contributions of deep bound states are included by using inverted fugacity expansions. The inversion of fugacities to densities is reduced to solvable algebraic problems and expressed by rational polynomials. The calculation of relative pressures is carried out separately for low and high densities. Near the crossing point, in between, the separate solutions are connected to each other by smooth concatenation. Applications to hydrogen–helium plasmas in the sun including estimates for the isentropic EOS are discussed.
Development and validation of an analytical method for the simultaneous determination of the alcohol biomarkers ethyl glucuronide, ethyl sulfate, N‐acetyltaurine, and 16:0/18:1‐phosphatidylethanol in human blood
Authors: Hofmann Vanessa , Sundermann Tom R. , Schmitt Georg , Bartel Marc 
Published: August 2021

AbstractAs alcohol is the most common addictive substance worldwide, it is inevitable to advance the established research. New and more substantial analytical methods can be applied to reply to complex questions in legal or forensic contexts. Therefore, an analytical method for the simultaneous determination of four different alcohol biomarkers—ethyl glucuronide, ethyl sulfate, N‐acetyltaurine, and 16:0/18:1‐phosphatidylethanol—in human blood was developed, validated, and verified. Despite the different chemical properties of the analytes, a specific determination via HPLC–MS/MS was achieved using a novel type of a Phenomenex Luna® Omega Sugar column. Furthermore, all criteria for a successful validation were fulfilled according to forensic guidelines. The method proved to be linear and demonstrates selectivity and sufficient sensitivity for every biomarker. LODs obtained with this method of 2.6 ng/ml (EtG), 4.7 ng/ml (EtS), 12.5 ng/ml (NAcT), and 6.9 ng/ml (PEth) were in an acceptable range for routine applications, and the stability of all analytes over a range of 12 h is given. The verification of the new developed method was performed with authentic samples. Thus, whole blood and postmortem samples were analyzed to obtain information about the drinking behavior, which can answer complex questions regarding alcohol consumption.
Multiple coping strategies maintain stability of a small mammal population in a resource‐restricted environment
Authors: Polyakov Anne Y. , Tietje William D. , Srivathsa Arjun , Rolland Virginie , Hines James E. , Oli Madan K. 
Published: August 2021

AbstractIn semi‐arid environments, aperiodic rainfall pulses determine plant production and resource availability for higher trophic levels, creating strong bottom‐up regulation. The influence of climatic factors on population vital rates often shapes the dynamics of small mammal populations in such resource‐restricted environments. Using a 21‐year biannual capture–recapture dataset (1993 to 2014), we examined the impacts of climatic factors on the population dynamics of the brush mouse (Peromyscus boylii) in semi‐arid oak woodland of coastal‐central California. We applied Pradel's temporal symmetry model to estimate capture probability (p), apparent survival (φ), recruitment (f), and realized population growth rate (λ) of the brush mouse and examined the effects of temperature, rainfall, and El Niño on these demographic parameters. The population was stable during the study period with a monthly realized population growth rate of 0.993 ± SE 0.032, but growth varied over time from 0.680 ± 0.054 to 1.450 ± 0.083. Monthly survival estimates averaged 0.789 ± 0.005 and monthly recruitment estimates averaged 0.175 ± 0.038. Survival probability and realized population growth rate were positively correlated with rainfall and negatively correlated with temperature. In contrast, recruitment was negatively correlated with rainfall and positively correlated with temperature. Brush mice maintained their population through multiple coping strategies, with high recruitment during warmer and drier periods and higher survival during cooler and wetter conditions. Although climatic change in coastal‐central California will likely favor recruitment over survival, varying strategies may serve as a mechanism by which brush mice maintain resilience in the face of climate change. Our results indicate that rainfall and temperature are both important drivers of brush mouse population dynamics and will play a significant role in predicting the future viability of brush mice under a changing climate.
Corallivory varies with water depth to influence the growth ofAcropora hyacinthus, a reef‐forming coral
Authors: Ladd Mark C. , Winslow Erin M. , Burkepile Deron E. , Lenihan Hunter S. 
Published: August 2021

AbstractA long‐held paradigm is that water depth has a strong influence on coral performance mainly due to the rapid attenuation of light. Yet, many factors influence coral performance across reefscapes, including corallivory. How coral demographic performance changes with water depth and the intensity of corallivory has not been tested but is intriguing because fish abundance and community composition change substantially with water depth. We tested the independent and interactive effects of water depth and corallivory on the growth rates of a reef‐building coral,Acropora hyacinthuscommon throughout the Indo‐Pacific. Our study was conducted on the fore reef of Mo’orea, French Polynesia, where shallower coral populations have recovered more quickly than deeper populations after a major disturbance that culminated in 2010. Contrary to predictions of the light‐attenuation paradigm, water depth (5 vs. 10 vs. 17 m) did not influence coral growth, regardless from what depth corals were collected. However, the effects of corallivory varied by depth as coral predators significantly reduced the growth rates ofA. hyacinthusat 5 and 10 m depth, where the abundance of corallivores and rates of corallivory were greatest. There were no effects of predation on coral growth rates at 17 m, where the intensity of corallivory was lowest. Our results imply that corallivory is not a dominant factor establishing the distribution ofA. hyacinthuscorals across water depth. Instead, we found that partial predation may limit the potential for recovery ofA. hyacinthusin relatively shallow water, where this coral is most abundant. As the frequency and intensity of disturbances impacting coral reef ecosystems increase with climate change and other anthropogenic factors, chronic predation on corals by corallivorous fish may play an increasingly important role in coral community recovery.
High‐sensitivity cardiac troponin T determines all‐cause mortality in cancer patients: a single‐centre cohort study
Authors: Finke Daniel , Romann Sebastian W. , Heckmann Markus B. , Hund Hauke , Bougatf Nina , Kantharajah Ajith , Katus Hugo A. , Müller Oliver J. , Frey Norbert , Giannitsis Evangelos , Lehmann Lorenz H. 
Published: August 2021

AbstractAimsCardio‐oncology is a growing interdisciplinary field which aims to improve cardiological care for cancer patients in order to reduce morbidity and mortality. The impact of cardiac biomarkers, echocardiographic parameters, and cardiological assessment regarding risk stratification is still unclear. We aimed to identify potential parameters that allow an early risk stratification of cancer patients.Methods and resultsIn this cohort study, we evaluated 930 patients that were admitted to the cardio‐oncology outpatient clinic of the University Hospital Heidelberg from January 2016 to January 2019. We performed echocardiography, including Global Longitudinal Strain (GLS) analysis and measured cardiac biomarkers including N‐terminal pro brain‐type natriuretic peptide (NT‐proBNP) and high‐sensitivity cardiac troponin T levels (hs‐cTnT). Most patients were suffering from breast cancer (n = 450, 48.4%), upper gastrointestinal carcinoma (n = 99, 10.6%) or multiple myeloma (n = 51, 5.5%). At the initial visit, we observed 86.7% of patients having a preserved left ventricular ejection fraction (LVEF >50%). At the second follow up, still 78.9% of patients showed a preserved LVEF. Echocardiographic parameters or elevation of NT‐proBNP did not significantly correlate with all‐cause mortality (ACM) (logistic regression LVEF <50%: P = 0.46, NT‐proBNP: P = 0.16) and failed to identify high‐risk patients. In contrast, hs‐cTnT above the median (≥7 ng/L) was an independent marker to determine ACM (multivariant logistic regression, OR: 2.21, P = 0.0038) among all included patients. In particular, hs‐cTnT levels before start of a chemotherapy were predictive for ACM.ConclusionsBased on our non‐selected cohort of cardio‐oncological patients, hs‐cTnT was able to identify patients with high mortality by using a low cutoff of 7 ng/L. We conclude that measurement of hs‐cTnT is an important tool to stratify the risk for mortality of cancer patients before starting chemotherapy.
αβ T cells replacing dermal and epidermal γδ T cells in Tcrd−/− mice express an MHC‐independent TCR repertoire
Authors: Binz Christoph , Bubke Anja , Sandrock Inga , Prinz Immo 
Published: August 2021

AbstractThe epidermis of mouse skin is usually populated by dendritic epidermal T cells (γδDETC) expressing an invariant Vγ5Vδ1+ TCR. In Tcrd−/− mice, skin‐resident γδDETC are replaced by αβDETC carrying polyclonal αβ TCRs. Although they exhibit a dendritic morphology, αβDETC were reported to be less functional than genuine γδDETC, likely because their TCR is unable to interact with the original TCR ligands of γδDETC. However, the TCR repertoire of those replacement DETC in Tcrd−/− mice might provide clues for understanding the development and selection of canonical γδDETC. Here, we compare the phenotype and TCR repertoires of wild‐type and Tcrd−/− mouse skin T cells. Our data reveal that αβDETC are CD4/CD8 double negative and express an MHC‐independent TCR repertoire. Furthermore, we identify a second MHC‐independent population of CD103hi CD4/ CD8 double‐negative αβ T cells in the dermis of Tcrd−/− mice.