bluuebunny/crossref_metadata_2025_split huggingface dataset:
Changes in Denture Retention With Denture Adhesives and Oral Moisturizers for the Oral Cavity
Authors: Ikemura Naoya , Sato Yuji , Furuya Junichi , Shimodaira Osamu , Takeda Kana , Kakuta Takuya , Yamane Kunihito , Kitagawa Noboru 
Published: April 2021

Abstract
Background: It is difficult to maintain dentures during meals. This study aimed to assess changes in denture retention between rest and function using denture adhesives and oral moisturizers in an oral cavity model.Methods: The following test samples were applied between the palatal plate and the edentulous jaw ridge model: denture adhesive, denture adhesive for dry mouth, oral moisturizer, and denture moisturizer. The retentive force was measured under two conditions: at rest while immersed in water and during function with a 2.5-kg load applied. The plate was pulled perpendicular to the occlusal plane and the retentive force was measured using a digital force gauge.Results: Under dry conditions, denture adhesive for dry mouth and oral moisturizer had a significantly higher retentive force than denture adhesive and denture moisturizer. After 30 min of immersion in water, the retentive force of the denture adhesive increased while that of the oral moisturizer decreased. After 30 mins of function, the retentive force of the denture adhesive and denture adhesive for dry mouth remained high, while that of the oral moisturizer and denture moisturizer significantly decreased. Between rest and function, the retentive force of the denture adhesive and denture adhesive for dry mouth was high, and that of the oral moisturizer was low.Conclusions: Immediately after use, denture adhesive for dry mouth exhibited high retentive force, but retention gradually decreased due to its water content. Clinical Significance: Denture adhesives for dry mouth can be useful for retaining dentures during 30-min meals.
Has the Local Area Network (LAN) the Same Characteristics With the Particle/field Entity? Recovering the Schwarzschild Metric in a Discrete and Flat Spacetime, Using a Diffusion-driven Impurity Model Produced by Partile/LAN Entities.
Authors: Chatzichristos Aris 
Published: April 2021

Abstract
A local area network (LAN) consists typically of several telecommunication nodes, all of which share a public IP address and a single point of contact with the Internet, namely the router. For an outside observer, the whole LAN with all its nodes would look point-like (having one, shared, "public IP" address and a single connection with the Internet), but in its interactions it would appear field-like, as a LAN of several nodes, each with its own "private IP" address, has an internal structure and interacts with the outside world differently than a single node would. In this study, the above particle/LAN analogy will be used as a basis of Átmiton theory, according to which, elementary particles are made of LANs consisting of a type of telecommunication node - called átmiton - and space is a 3D network of átmita with the simple cubic topology. In this work, it is demonstrated that connecting a particle/LAN entity on the lattice of space distorts its local topology, effectively introducing a crystal defect to the lattice of space. This defect increases the distance between points lying at opposite sides of it. The internal interactions of any massive object should be producing constantly copious numbers of such space-defects, which diffuse away from their source, by means of a random walk. Here it is suggested that general relativity's notion of spacetime's curvature is equivalent to the aforementioned diffusion-driven impurity model in the flat, discrete lattice of space of Átmiton theory. Their equivalency is demonstrated for the specific case of a spherical mass, around which the Schwarzschild metric is shown to be valid.
Role of Surgical Treatment in Primary Intestinal Non-Hodgkin Lymphomas: A SEER Population-Based Survival Analysis
Authors: Zhang Cuifen , Zhang Xiaohong , Liu Zeyu , Tao Jiahao , Lin Lizhu , Zhai Linzhu 
Published: April 2021

Abstract
Evidence regarding the need for surgery for primary intestinal non-Hodgkin lymphoma (PINHL) patients with chemotherapy is limited and controversial. We aimed to investigate the specific impact of surgery on survival of PINHL patients. Data from PINHL patients (aged >18 years) with chemotherapy between 1983 and 2015 were extracted from the Surveillance, Epidemiology, and End Results (SEER) database. We concerned about overall survival (OS) and improved cancer-specific survival (CSS). Propensity score matching (PSM) analysis was also used to explore the reliability of the results to further control for confounding factors. Finally, we screened 3537 patients. Multivariate regression analysis showed that patients with surgery and chemotherapy had better OS (hazard ratio [HR], 0·83; 95% confidence interval [CI], 0·75–0·93; P=0·0009) and CSS (HR, 0·87; 95% CI, 0·77–0·99; P=0·0404) compared with the non-operation group after adjusting for confounding factors. After PSM analysis, compared with non-surgery, surgery remained associated with improved OS (HR, 0·77; 95% CI, 0·68–0·87; P<0·0001) and improved CSS (HR, 0·82; 95% CI, 0·72–0·95; P=0·008) adjusted for baseline differences. In the large cohort of PINHL patients with chemotherapy older than 18 years, surgery was associated with significantly improved OS and CSS before and after PSM analysis.
Promoting or Inhibiting? The Impact of Enterprise Environmental Performance on Economic Performance: Evidence From China's Large Iron and Steel Enterprises
Authors: Liu Rong , He Feng , Ren Jianyu 
Published: April 2021

Abstract

In recent years, people have realized the importance of corporate environmental responsibility. In this study, we combine the Slack-based Measurement (SBM) model with the "Super-efficiency" model to construct the environmental performance evaluation based on Data Envelopment Analysis (DEA) to measure the environmental performance of China's large iron and steel enterprises from 2009 to 2017. Then, it studies the impact of environmental performance on enterprise economic performance through regression analysis. The results show that the impact of environmental performance of China's large iron and steel enterprises on economic performance shows an inverted U-shaped relationship. The conclusion is helpful to encourage enterprises to actively carry out environmental management, so as to maintain and enhance the competitiveness of enterprises. Therefore, this paper suggests that iron and steel enterprises should balance the relationship between environmental responsibility and economic performance in order to maximize enterprise performance. The main purpose of this paper is to let enterprises solve the negative externalities in production through internalization, and encourage enterprises to adopt environmental protection behavior for production and operation.
Adsorption and desorption characteristics and mechanism of Cd in reclaimed soil under the influence of dissolved organic carbon
Authors: Zheng Yonghong , Zhang Zhiguo , Chen Yongchun , An Shikai , Zhang Lei , Chen Fangling , Ma Chengnan , Cai Weiqing 
Published: April 2021

Abstract
Organic acids are widespread in the environment and play an important role in the adsorption, desorption, and migration of soil Cd. This study evaluated the characteristics and mechanism of Cd adsorption and desorption in reclaimed soil from Panyi Mine in the Huainan mining area under the influence of humic acid (HA) and citric acid (CA). The addition of HA and CA inhibited the adsorption and enhanced the desorption of Cd in reclaimed soil, with HA having a stronger effect than CA. As the concentration of added HA or CA increased, the adsorption capacity of Cd in the reclaimed soil gradually decreased, while the desorption capacity gradually increased. That is, the adsorption inhibition/desorption promotion effect was stronger for higher concentrations of organic acid. Cd adsorption and desorption could be described as a logarithmic function of organic acid concentration. The kinetic curves of Cd adsorption and desorption in reclaimed soil under the influence of organic acids show that both adsorption and desorption involved two stages: a fast reaction stage followed by a slow reaction stage.
Socio-Economic Inequalities in the Chronic Diseases Management among Chinese Adults Aged 45 years and Above: A Cross Sectional Study
Authors: GUO JING , Li Jiasen , Huang Kehui , Feng Xing Lin 
Published: April 2021

Abstract
BackgroundsNon-communicable diseases (NCDs) have become a priority public health issue. The aim of this study was to examine whether social-economic inequalities exist in chronic disease management among Chinese adults, and whether the relationship between SES and chronic disease management mediated by social capital.MethodsWe used combined data from China Health and Retirement Longitudinal Study (CHARLS). A total of 19291 subjects, including 14905 subjects from 2011 survey, 2036 subjects from 2013, and 2350 subjects from 2015 was included in this study.ResultsSubjects living in urban setting, with higher education attainment and economic status were more likely to have annual health checks, and to be diagnosed for those with hypertension, diabetes and dyslipidemia (all P<0.05). Social participation could mediate the association between social economic status (SES) and annual health checks, diagnosis of hypertension and dyslipidemia, and health education of hypertension. Health checks could mediate the association between social participation and the diagnosis of hypertension, diabetes and dyslipidemia. The proportions of mediation were 17.5%, 23.9% and 8.9%, respectively. There were no mediating effects observed from cognitive social capital variable-perceived helpfulness.ConclusionIt is necessary to deeply reform our social security system and enhance the social capital construction to promote those low SES people’s physical health.
Multitask Model for Person Re-identification by Attribute-aware
Authors: Pei Shengyu , Fan Xiaoping 
Published: April 2021

Abstract
The image-based person re-identification problem can be transformed into a similar image retrieval problem. At present, most of the current identity-based methods do not consider pedestrian attributes. Moreover, many methods that consider pedestrian attributes and identities fail to fully simulate the relationship between pedestrian attributes and identities. In this article, we propose a new image-based person re-identification method by attribute-aware. Based on the introduction of instance batch normalization, the non-local module based on attention is used to transform the ResNet network structure to improve the feature extraction performance. After using generalized mean pooling for feature aggregation, the identity-based and attribute-based double stream network modules pay attention to the relationship between identities and pedetrian features, and the relationship between attributes and pedestrian features, so as to fully activate the relationship between pedestrian attributes and identities. Experiments are carried out on two classic person re-identification by attribute dataset Market-1501 and DukeMTMC-reID, and the results prove the effectiveness of the method. The method proposed in this paper has achieved the best performance on some evaluation metrics.
Interventions to Mitigate COVID-19 Misinformation: Protocol for a Scoping Review
Authors: Kumar Navin , Walter Nathan , Nyhan Kate , Khoshnood Kaveh , Tucker Joseph D , Bauch Chris T , Ding Qinglan , Jones-Jang S Mo , Choudhury Munmun De , Schwartz Jason , Nyhan Brendan J , Papakyriakopoulos Orestis , Forastiere Laura 
Published: April 2021

Abstract
Background: The duration and impact of the COVID-19 pandemic depends in a large part on individual and societal actions which is influenced by the quality and salience of the information to which they are exposed. Unfortunately, COVID-19 misinformation has proliferated. To date, no systematic efforts have been made to evaluate interventions that mitigate COVID-19-related misinformation. We plan to conduct a scoping review that seeks to fill several of the gaps in the current knowledge of interventions that mitigate COVID-19-related misinformation.Methods: A scoping review focusing on interventions that mitigate COVID-19 misinformation will be conducted. We will search (from January 2020 onwards) MEDLINE, EMBASE, CINAHL, PsycINFO, Web of Science Core Collection, Africa-Wide Information, Global Health, WHO Global Literature on Coronavirus Disease Database, WHO Global Index Medicus, and Sociological Abstracts. Grey literature will be identified using Disaster Lit, Google Scholar, Open Science Framework, governmental websites and preprint servers (e.g. EuropePMC, PsyArXiv, MedRxiv, JMIR Preprints). Study selection will conform to Joanna Briggs Institute Reviewers’ Manual 2020 Methodology for JBI Scoping Reviews. Only English language, original studies will be considered for inclusion. Two reviewers will independently screen all citations, full-text articles, and abstract data. A narrative summary of findings will be conducted. Data analysis will involve quantitative (e.g. frequencies) and qualitative (e.g. content and thematic analysis) methods.Discussion: Original research is urgently needed to design interventions to mitigate COVID-19 misinformation. The planned scoping review will help to address this gap.Systematic Review registrations: Systematic Review Registration: Open Science Framework (osf/io/etw9d).
Wetland Landscape Pattern Evolution and Prediction in the Yellow River Delta
Authors: ZHOU Ke 
Published: April 2021

Abstract
Starting from the overall pattern of wetland evolution in the Yellow River Delta, The combination of CA-Markov model and MLP model is studied. Based on the low-medium resolution Landsat data and the field survey data, the evolution trend of wetland landscape pattern in the Yellow River Delta is simulated and predicted by using the proposed models. Taking high resolution (2m) data in 2016 as the precision verification, the model simulation results are validated. The results show that the area of natural wetlands in the Delta was decreased from 2593.63 km2 in 1976 to 1639.60 km2 in 2016, a total area of 954.03 km2 was reduced. According to the model simulation, the natural wetland area in 2026 is predicted to be 1252.7 km2, the constructed wetland area will be 1265.0 km2, the non-wetland area will be 924.5 km2. The constructed wetland in the Yellow River Delta is increasing and spreading into the sea, but the area of natural wetland has been decreasing. If this trend be developed, the national natural wetland conservation target would not be realized. The results are of great significance to the wetland development planning, management and protection in the Yellow River Delta.
Using A Combination Of Chitosan, Methyl Jasmonate, and Cyclodextrin as an Effective Elicitation Strategy for Prenylated Stilbene Compound Production In Arachis Hypogaea L. Hairy Root Culture and Their Impact on Genomic DNA
Authors: Chayjarung Phadtraphorn , Poonsap Wannakan , Pankaew Chanyanut , Inmano Onrut , Kongbangkerd Anupan , Limmongkon Apinun 
Published: April 2021

Abstract
Peanut (Arachis hypogaea L.) hairy roots are a potential tool for stilbene compound production. This study focuses on the most efficient elicitation strategy for inducing stilbene compound production, especially for the prenylated forms of trans-arachidin-1 and trans-arachidin-3. To the best of our knowledge, this is the first report of simultaneous treatment involving chitosan (CHT), methyl jasmonate (MeJA), and cyclodextrin (CD); CHT+MeJA+CD in peanut hairy roots to induce substantial amounts of trans-arachidin-1 and trans-arachidin-3 at 72 h of the elicitation period. The results demonstrate the highest amounts of trans-arachidin-1 and trans-arachidin-3, with 684.30 ± 183.85 and 543.94 ± 171.17 mg/g dry weight of hairy roots, respectively. The highest antioxidant capacity determined by ABTS and FRAP assays was 188.95 ± 0.43 µmol Trolox/g dry weight of hairy roots and 24.61 ± 0.50 mg ascorbic acid/g dry weight of hairy roots, respectively, while the highest phenolic content was also detected in this crude extract, with 8.67 ± 0.11 mg gallic acid/g dry weight of hairy roots. The antioxidant and pro-oxidant activity of the CHT+MeJA+CD crude extract in the protection and damage of DNA is of great interest and can have major positive impacts on health promotion and disease prevention.
Taurine Promotes Axonal Sprouting Through Mitochondrial Improvement in Stroke
Authors: He Weiliang , Tian Xiaochao , Zhang Kaihua , Wang Hebo 
Published: April 2021

Abstract
BackgroundBrain plasticity including axonal sprouting has been recognized in restoring motor function in ischemic stroke. Mitochondrion plays a crucial role in determining axonal sprouting in ischemic injury. Taurine (TAU) could protect brain against experimental stroke as one of the richest amino acids. However, the role of TAU on axonal sprouting and the specific potential mechanism on mitochondria of stroke were unclear. MethodsFocal cerebral cortical ischemia in C57BL/6 mice was preceded. Motor function was assayed by the Rota-Rod test on D7, D14, and D28 after stroke. Axonal sprouting was detected using immunocytochemistry with biotinylated dextran amine (BDA). The expressions of mitochondrial DNA (mtDNA), Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PCG-1a) and Transcription factor A of mitochondria (TFAM) were measured by RT-qPCR. ResultsTAU treatment significantly recovered the motor function of focal cerebral cortical ischemic mice. And TAU promoted axonal sprouting. It was also observed that TAU enhanced mtDNA content, increased the levels of Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PCG-1a) and Transcription factor A of mitochondria (TFAM). ConclusionsCollectively, the data illustrated that TAU exerted a promoting influence on axonal sprouting, through mitochondrial improvement in cerebral ischemic stroke.
A retrospective review of non‐intestinal‐Type adenocarcinoma of nasal cavity and paranasal sinus.
Authors: Li Jinmei , Chen Bei , Li Baofeng , Xu Jin , Ye Feng , Xu Yuting , Wu Shuhua , Cheng Shuqiong , Lu Yinghao , Guan Jian 
Published: April 2021

Abstract
Background: Adenocarcinomas of the nasal cavity and paranasal sinus, which includes non-intestinal adenocarcinoma of nasal cavity and paranasal sinuses (n-ITAC), are rare and heterogeneous. The diagnosis of n-ITAC is commonly achieved by exclusion, and several entities of considerable biological diversity are included. The literature on n-ITAC is rarely reported. It is reported in the literature that the prognosis of most sinonasal adenocarcinomas still remains poor. We hope that the analysis can provide recommendations for the treatment of n-ITAC.Objective: To analyze the clinical characteristics, outcomes, prognostic factors and the best treatment of n-ITAC.Methods: We located the time on the PACS system of Southern Hospital of Southern Medical University from February 1995 to February 2020. We searched the keyword " n-ITAC " and selected pathology. A total of 16 patients were searched, of which 2 were undiagnosed and 1 lost follow-up. Finally, we analyzed a total of 13 n-ITAC patients.Results: The follow-up time was 34.6 months in average. The 1-year overall survival (OS) rate of G1 tumors was 100%, and the 3-year OS rate was 71.4%. The 1-and 3-year OS rates of G3 tumors were 50% and 16.7%, respectively. It was significantly associated with OS (p=0.03). Pathological grade is an independent prognostic factor. The OS of the surgery group was significantly better than that of the non-surgery group (1-year OS was 90.9% vs 0%, 3-year OS was 54.5% vs 0% P < 0.001). Surgery is an indispensable means of treatment and benefit. Patients with certain risk factors were given radical radiotherapy. The radiation dose for cases without surgery or with positive surgical margin was 66-70Gy/33F, and the dose for cases with negative margin was 60Gy/28F. Conclusions: N-ITAC is a rare disease, and high-grade tumors have a poor prognosis. Surgery is still the main treatment for n-ITAC. Patients with no surgery, high-grade tumors and/or positive surgical margins should be given radical radiotherapy, and preventive radiotherapy in the drainage area of the lymph node at the same time. If the margins are negative, the radiation dose can be appropriately reduced. Whether combined with chemotherapy and targeted therapy needs further study.
The Role of SRMS in Colorectal Cancer by Bioinformatics Analysis
Authors: Zhang jie , Liu Weidong , Feng Sisi , Zhong Baiyun 
Published: April 2021

Abstract
Background:Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristoylation sites (SRMS) is a non-receptor tyrosine kinase that has been found to be overexpressed in various tumors. Therefore, it may be an important carcinogenic factor whose role in colorectal cancer (CRC) has not been established. Methods: We evaluated the expression patterns of SRMS in CRC using GEPIA, Oncomine and HPA datasets while the association between SRMS and clinicopathological features was analyzed using a UALCAN dataset. LinkedOmics was used to determine co-expression and functional networks associated with SRMS. Besides, we used TISIDB to assess the correlation between SRMS and immune signatures, including tumor-infiltrating immune cells and immunomodulators. Lastly, protein-protein interaction network establishment and pathway enrichment analysis of the SRMS-associated 33 immunomodulators and 191 immune cell marker genes were performed using the STRING portal. Results: Compared to normal colorectal tissues, SRMS was found to be upregulated in CRC tissues, and was correlated with higher pathological stages and nodal metastasis status. Functional network analysis suggested that SRMS regulates intermediate filament-based processes, protein autophosphorylation, translational initiation and elongation signaling through pathways involving ribosomes, proteasomes, oxidative phosphorylation, and DNA replication. In addition, SRMS expression was correlated with infiltrating levels of CD4+ T cells, CD56dim, MEM B, Neutrophils, Th2, Th17, and Act DC. Pathway enrichment analysis of SRMS-associated 33 immunomodulators and 191 immune cell marker genes indicated that they are involved multiple cancer-related pathways. Conclusions: SRMS is a promising prognostic biomarker and a potential therapeutic target for CRC patients. In particular, SRMS regulates CRC progression by modulating chemokines, IL-17, intestinal immune networks for IgA production, and cytokine-cytokine receptor interaction signaling pathways among others. However, more studies are needed to validate these findings.