bluuebunny/crossref_metadata_2025_split huggingface dataset:
IDENTIFIKASI DAN PENETAPAN KADAR RHODAMIN B DALAM KERUPUK BERWARNA MERAH YANG BEREDAR DI PASAR ANTASARI KOTA BANJARMASIN
Authors: Kumalasari Eka 
Published: January 2021

Crackers are made from tapioca flour batter mixed with flavorings and colorings, still many outstanding crackers that contain ingredients banned dye Rhodamine B. Rhodamine B is a chemical used for red dye in the textile industry and plastic. Rhodamine B can cause cancer, poisoning, lung irritation, sore eyes, and sore throat. This study aims to identify and determination the levels of Rhodamine B in circulating red crackers Antasari market Banjarmasin.The population is that sold in the red crackers that sold in Antasari market Banjarmasin.. The sampling is technique incidental sampling , that is based on chance, so any population by chance met with researchers can be used as a sample. Identification of Rhodamine B was done by Thin Layer Chromatography (TLC) by using the stationary phase silica GF 254 and mobile phase is elution solvent is n-butanol, ethyl acetate, ammonia (10:4:5). Then detected with a UV lamp 254 nm and 366 nm. While for the determination of levels using Vis spectrophotometry at a wavelength of 544 nm.The results showed that the samples of 6 found one sample containing Rhodamine B, namely samples 5 (cassava crackers matches) and obtained values of 7,25 ± 3,8640 levels mg / kg. Based on these results, Rhodamine B still found in crackers that sold in the market Antasari Banjarmasin.
STABILITAS DAN AKTIVITAS GEL EKSTRAK BULBUS BAWANG TIWAI (Eleutherine americana (Mill.) Urb.) SEBAGAI ANTI ACNE
Authors: Warnida Husnul , Sukawaty Yullia , Mega Mega 
Published: January 2021

awang Tiwai has an antibacterial activity toward some microorganisms e.g. Staphylococcus epidermidis dan Propionibacterium acne, two acne related bacteria. Bawang Tiwai extract 1% and 2% were formulated into gel (no oil content, because oil could make the acne worse) with carbomer 940 as gelling agent. Physical stability of bawang tiwai gel was evaluated included stability, organoleptic, pH, homogeneity, viscosity, consistency, spreading test, and activity toward Staphylococcus epidermidis. The result showed that all formulas are stable after 7 days. The test results of antibacterial activity gel are 17,24 mm dan gel 19,75 mm to gel 1% dan 2% respectively.
PERBEDAAN PENGETAHUAN DAN SIKAP PASIEN DIABETES MELLITUS RAWAT INAP RUMAH SAKIT ISLAM SAMARINDA SEBELUM DAN SESUDAH KONSELING GIZI DENGAN MENGGUNAKAN MEDIA AUDIOVISUAL
Authors: Siswanto Siswanto , Kamba Ismail , Aminah Siti 
Published: January 2021

Diabetes mellitus is one of the communicable diseases that have become a public health problem, not only in Indonesia but also the world. Currently morbidity of diabetes mellitus is increasing every year, where in 2006 there were 14 million people in 2011 and ranks fourth with 773 cases. DM is also a cause of disease mortality by 5.8%. And Samarinda own particular Islamic Hospital years 2009, there were 449 patients with DM, and 2011 an increase in the 1931 patients with diabetes mellitus. To increase patients’ knowledge about diabetes and diabetic patients be directing attitudes that support or positive attitude towards keeping blood glucose levels to remain normal. Methode to use pra eksperiment with one group pretest posttest. individual conseling withAudiovisual media. There is increased knowledge about diabetes diabetic patients before and after intervention with increasing value of 3.77 (p value = 0.000) and increase in attitudes regarding diabetes mellitus diabetic patients with an increase in the value of 5,35 (p value = 0.003). There was an increase in knowledge and attitudes of patients hospitalized with diabetes mellitus hospital after islam samarinda given nutritional counseling using audio-visual media
UJI PENDAHULUAN DAUN TENEM Litsea cubeba (Lour.) Pers
Authors: Supriningrum Risa , Hendra Medi , Misak Hendri 
Published: January 2021

Litsea cubeba (Lour Pers.) has been used by the Dayak community Lundayeh and Kenyah, the village of Long Berang, District Mentarang, North Borneo, as drug . Leaves and bark used as medicine for diarrhea. Preliminary data concerning the characteristics and content of secondary metabolites has not been reported. This study aims to determine the organoleptic, macroscopic, microscopic characteristics and content of secondary metabolites tenem leaves. The results showed that the leaf tenem have organoleptic characteristics typical aromatic smell like citrus (lemon), taste slightly bitter, slightly spicy, chelates. Macroscopic characteristics in the form of a single leaf, lanceolate, elongated, tapered leaf tip, leaf base tapering, bone pinnate leaves, upper surface shiny, lower surface dull and slightly hairy, color light green to dark green. Microscopy test results showed fragments of sklereid, oil cell, stomata type of parasitic, non-glandular trichomes. Simplicia tenem leaf powder contains alkaloids, tannins and terpenoids. The ethanol extract of leaves tenem containing compounds, terpenoids, tannins, alkaloids
UJI EFEKTIFITAS FORMULA SPRAY DARI MINYAK ATSIRI HERBA KEMANGI (Ocimum Sanctum L ) SEBAGAI REPELLENT NYAMUK Aedes aegypti
Authors: Aini Resmi , Widiastuti Rina , Nadhifa Nuha Afra 
Published: January 2021

Dengue fever is transmitted by the bite of Aedes aegypti mosquitoes infected with denguevirus. Preparations antinyamuk much use of harmful chemicals such as DEET (diethylmetatoluamide) and permethrin that can lead to pollution of the environment, leavingno residue and cause resistance to the drug. To determine the activity of essential oils from herbs basil (Ocimum Sanctum L) in the preparation of spray as a mosquito repellent and determine the effective concentrationof the spray.This type of research is True experiment with design Post Test Only Control Group Design. Repellent activity was observed by means of spray is sprayed on the back of the hand probandus, then tested on female mosquitoes with the introduction into the cage containing20 mosquitoes each treatment. Spray essential oils showed repellent activity of Aedes aegypti with a value of correlation r = 0.964 higher concentration of essential oils the fewer mosquitoes that land. Spray herbal essential oil of basil (Ocimum basilicum L) has a repellent activitycompared to the negative control. The effectiveness of the herb basil essential oil sprayobtainedat 74.131 ppm lC50 and lC90 of 775.711 ppm
POTENSI TONGKOL JAGUNG (Zea Mays L.) SEBAGAI SUNSCREEN DALAM SEDIAAN HAND BODY LOTION
Authors: Ekowati Dewi , Hanifah Inaratul Rhizky 
Published: January 2021

The over exposure sunlightis on the skin provides of damage. Skin damage caused the over exposure sunlightis can occur in the short term such as erythema or long term such as premature skin aging and even skin cancer. One way that can be done to minimize the amount of UV that penetrated into the skin is to use sunscreen. Corn cob contain the chemical compounds of phenolic, which suspected to have the protection activity toward the UV B rays. The study aims to make preparations hand body lotion that meet good physical quality of the corn cob extract as a sunscreen. Hand made three body lotion formula with extract concentrations of corn cob 10% FI, FII FIII 15% and 20%. Testing the physical properties of the test hand body lotion include viscosity, dispersive power and pH. The effectiveness of a sunscreen is based on a determination of the value of the Sun Protection Factor (SPF) in vitro. The third formula has a good physical quality lotion that viscosity 50-1000 dPas, the scatter 5-7 cm, pH 4.5 -7. The effectiveness of sunscreen based on the value of the Sun Protection Factor (SPF), the effectiveness FIII in the category of extra protection is 7.23. SPF value FI FII 5.13 and 5.67 so that FI and FII into the category of moderate protection
PENGARUH PERBEDAAN CHEMICAL PENETRATION ENHANCER PADA PENETRASI TRANSDERMAL PATCH PROMETAZIN HCL
Authors: Nurahmanto Dwi 
Published: January 2021

This research aims is to create a promethazine HCl patch transdermal drug delivery systems with the most excellent penetration. Transdermal drug delivery can be efficiently used for the active agents which undergo rapid first pass metabolism and oral absorption is often disrupted by nausea and vomiting, hence the transdermal patches of promethazine HCl were prepared by using different penetration enhancers, propylene glycol, oleic acid and isopropyl alcohol. The prepared formulations were evaluated for thickness, weight variation, moisture content, drug content, morphology, and in vitro permeation studies. The patch morphology studies were performed by Scanning Electron Microscopy (SEM). The amount of promethazine HCl transfered by propylene glycol 25.77 ± 3.0396 ug, isopropil alcohol 25.758 ± 2.9022 ug and oleic acid 25.017 ± 8.1300 ug. The penetration of promethazine HCl patch with oleic acid enhancer, produce the highest penetration than isopropil alcohol and propylene glycol. there was no difference in penetration using propylene glycol and isopropyl alcohol. Oleic acid is the best enhancer for preparations patch containing promethazine HCl although the amount of promethazine HCl contained is the least. The whole formulations comply with the patch dosage requirements
VALIDASI METODE ANALISIS DAN PENURUNAN KADAR INFUS CIPROFLOKSASIN YANG DIPENGARUHI REAKSI OKSIDASI MENGGUNAKAN HPLC
Authors: Nugraheni Bekti , Nafi'ah Nafi'ah , Anggoro B 
Published: January 2021

Validation of analysis methods is conducted on the assay of the antibiotic ciprofloxacin because it is often used in the treatment of urinary tract infections, respiratory tract infections and gastrointestinal infections. This study aimed to determine the validity of an analytical method. Development of methods used in this study were the mobile phase of methanol: aquabidest : 0.1 M phosphate buffer: acetonitrile (80: 10: 5: 5). Then the ciprofloxacin validation was performed. After the methods validation were valid, the assay of ciprofloxacin in infusion was performed to determine the decreased levels which affected by the oxidation reaction of 0, 60, 90, 150 and 180 minutes. The validation parameters in the research were selectivity, accuracy, precision, linearity, LOD and LOQ. Samples were standart ciprofloxacin used for the validation and infusion of ciprofloxacin for the assay on the sample application that was affected by the oxidation reaction. The used of HPLC met the requirements such as HPLC devices Waters e2695 Separations, SunFireTM column C18, and PDA detector and a flow rate of 1.0 mL / min. This study showed that the result was selective, stated with no emergence of peaks in the matrix. HPLC analysis methods on ciprofloxacin meet the acceptance criteria of accuracy % recovery value solution concentration of ≥10 mg / mL are 90-107%. Precision test qualifies % RSD for solution concentrations ≥10 mg / mL is <7.3%. Linearity r ≥0,997 then it can be concluded that the result was qualified. LOD value is 0.2707 µg / mL and the LOQ value is 0.9026 µg / mL. The results of the assay infusion of ciprofloxacin were found that there was a significant decrease in the levels of ciprofloxacin due to the influence of the oxidation reaction
PENGARUH LAYANAN PESAN SINGKAT PENGINGAT TERHADAP KEPATUHAN KONSUMSI OBAT PASIEN DM TIPE 2 DI PUSKESMAS MELATI KABUPATEN KAPUAS
Authors: Susanto Yugo , Alfian Riza , Riana Rinidha , Rusmana Ibna 
Published: January 2021

Diabetes mellitus is a chronic disease characterized by hyperglycemia and glucose intolerance. Patients with DM in Indonesia ranks 4th largest with a prevalence of 8.6 % of the total population. Patient compliance in the treatment greatly affect the success of the therapy. The purpose of this study was to determine the level of adherence before and after administration of short message reminders, as well as knowing the adherence changes that occur in patients with type 2 diabetes at the Puskesmas Melati Kabupaten Kapuas. This esearch was conducted by quasi experimental design, with prospective data collection during the period from May to June 2016. The intervention was giving short message service reminder. Subjects who met the inclusion criteria as many as 15 patients. The primary data collection is done by filling the questionnaire adherence MMAS and secondary data obtained from medical observation sheet. The results showed that in the pre intervention average value (mean) adherence by 5.8 or are in the low adherence rate, in post intervention average value of 7.4 or adherence are moderate adherence rates, with the rate of change (Δ) adherence towards better at 1.6. It can be concluded that the adherence were lower before than after giving short message service reminder. There was improvement in the adherence to taking medicine after giving short message service reminder. The giving short message service reminder increased the adherence to take medicine effectively
FORMULASI ORALLY DISINTERGRATING TABLET (ODT) EKSTRAK ETANOL DAUN KEMANGI (Ocimum americanum L.) DENGAN VARIASI KONSENTRASI EXPLOTAB®
Authors: Soemarie Yulistia Budianti , Sa'adah Hayatus , Marginingsih Tri 
Published: January 2021

Bad breath is usually caused by bacteria and leftovers in the mouth. Utilization of natural ingredients that can be used to overcome the problem of bad breath one of them by using basil leaves (Ocimum americanum L.), which has activity as an antibacterial. The development of the preparations was done on basil leaves to overcome bad breath is by formulating the basil leaves ethanol extract into the Orally Disintegrating Tablet (ODT) preparation. The purpose of this study was to investigate the effect of explotab® concentration variations on the physical properties of ODT and to determine the best of concentrations of Explotab® that fulfill the physical properties of ODT. The type of research conducted was an experimental study. Research object was basil leaves ethanol extract formulated into ODT with Explotab® 2% w/b, 4% w/w, 6% w/b and 8% w/w variation. Physical evaluations test then conducted including : the uniformity of weight evaluation, the hardness test, the friability test, and the dissolved time. The results showed that the explotab® concentration variations had an effect on the physical properties of tablets and the formula with the Explotab® 8% b/b concentration was the best formula that could produce the best ODT tablet with physical properties.

Keywords : Basil leaves (Ocimum americanum L.), Explotab®, Orally Disintegrating Tablet (ODT)
KARAKTERISTIK INFORMASI TERKAIT CARA PENGGUNAAN METERED-DOSE INHALER DENGAN SPACER YANG MENGANDUNG KOMBINASI BETA-2 AGONIS DAN KORTIKOSTEROID OLEH APOTEKER DI APOTEK WILAYAH SURABAYA TIMUR
Authors: Lorensia Amalia , Queljoe Doddy de , Valensia Yessica 
Published: January 2021

ABSTRACT
Treatment of respiratory disorders using a metered-dose inhaler (MDI) with spacer becomes one of the important points. Pharmacists at pharmacies are the final key in therapy to ascertain how the use of inhalation tools is correct. This study aims to determine the completeness of each step of information on how to use MDI with spacer given by pharmacists at pharmacies in East Surabaya. The research design used is cross-sectional study with the subject of research is pharmacist in pharmacy. The research variable is the explanation of how to use MDI inhaler with spacer. An assessment method of 8 steps on how to use MDI with spacer and each number gets a value. Research subjects were 22 pharmacists. Most pharmacists describe each step orally by using the tool directly, ie at step: 1a (77.27%), 1b (77.27%), 2 (81.81%), 3 (31.81%) , 4a (59.09%), 4b (13.63%), 5a (100%), 5b (63.63%), 6a (90.90%), 6b (40.90%), 8a (9 , 09%), and 8b (9.09%). Most of the pharmacists explain verbally with a demonstration tool but only one pharmacist can explain all the steps completely. Therefore, pharmacists need to improve IEC services related to the use of MDI with a spacer for respiratory treatment.

Keywords : information on how to use inhaler, Metered-Dose Inhaler (MDI), spacer, pharmacist, pharmacy
HUBUNGAN PENGETAHUAN DAN KEBUTUHAN PASIEN TERHADAP INFORMASI OBAT DI APOTEK AMANDIT FARMA BANJARMASIN
Authors: Sari Ratih Pratiwi , Putra Aditya Maulana Perdana , Masran Ulfah 
Published: January 2021

The current pharmaceutical service has shifted its orientation from drug oriented to patient oriented with reference to pharmaceutical care. Pharmaceutical service activities are not limited to drug preparation and drug delivery to patients but pharmacy needs to interact or communication with the patient. The purpose of this study was to determine how is the relationship between knowledge and patient needs for drug information at Amandit Farma Pharmacy Banjarmasin. This type of research is descriptive analysis. Sampling was taken on March 9 - April 8, 2018 by giving questionnaires to 250 patients who redeemed the prescription at Amandit Farma Banjarmasin Pharmacy using systematic random sampling method according to exclusion and inclusion criteria. Data analysis using Chi Square 3x3. Based on the results of this study can be known the relationship between knowledge and needs of patients on drug information at Amandit Farma Pharmacy in Banjarmasin is statistically meaningful
AKTIVITAS KOMBINASI EKSTRAK BAWANG DAYAK-METFORMIN TERHADAP GULA DARAH MENCIT
Authors: Putra Aditya Maulana Perdana , Pratiwi Ratih Sari 
Published: January 2021

Diabetes mellitus is a chronic disease that requires good medical treatment to prevent long-term complications. The proportion of DM patients in Indonesia in 2013 was 3,7 million. Indonesia as one of the countries with the highest diversity has natural resources that can be used as an alternative medicine for diabetes mellitus, one of them is dayak onion. Dayak onions themselves contain compounds that can reduce blood glucose levels. The use of traditional medicine in the community is sometimes combined with chemical drugs. So the purpose of this study was to determine the comparison of the combination activity of dayak onion extract – metformin with single metformin to reduce mice blood sugar induced by alloxan. This research includes experimental research. The test animals used were male white mice which were divided into 2 groups, namely the combination of dayak onion and metformin and the single metformin group. The dose of dayak onion extract used in this study was 100 mg / KgBB and the dose of Metformin used was 45 mg / KgBB. Measurement of glucose levels is carried out every 3 days for 15 days. The decrease in fasting blood glucose from the control group and the test group was analyzed by the General Linear Model test at a 95% confidence level. The results of this study indicate that the combination of dayak onion tuber extract and metformin has better hypoglycemic activity than single metformin. This result can be seen from the average glucose level from day 3 to 15 the combination of dayak onion tuber and metformin is lower than the average glucose level of single metformin. The results of GLM analysis showed the sigvalue <0,05 so it can be concluded that there is a difference in glucose levels between the combination of dayak onion tuber and metformin with a single metformin.
PENGARUH BASIS SALEP HIDROKARBON DAN BASIS SALEP SERAP TERHADAP FORMULASI SALEP SARANG BURUNG WALET PUTIH (Aerodramus fuciphagus)
Authors: Sandi Dita Ayulia Dwi , Musfirah Yaumi 
Published: January 2021

Swiftlet nest is edible bird’s nest (EBN). Edible bird’s nest contain EGF (Epidermal Growth Factor) that has a role in skin cell regeneration. This research aims to find out the effect of the hydrocarbon and absorption bases on the edible bird’s nest ointment (Aerodramus fuciphagus) from the physical character of each ointment. The edible bird’s nest ointment made into two formula with hydrocarbonand absorption bases. Each ointment tested of the physical characteristics include organoleptic test, homogenity test, pH test, spreading test, sticky test, and viscosity test. The data obtained was analyzed statistically using T Independent Test. The result showed that there was affect the hydrocarbon and absorption bases to the physical characteristics of edible bird’s nest ointment include spreadability (P 0,011), sticky (P 0,020), and viscosity, but there was not affect to organoleptic, homogenity and pH of edible white bird’s nest ointment (Aerodramus fuciphagus).
HUBUNGAN DERAJAT TROMBOSITOPENIA DENGAN MALARIA BERAT PADA PASIEN MALARIA DI RUMAH SAKIT KANUJOSO DJATIWIBOWO BALIKPAPAN
Authors: Siagian Loly R.D , Zubaidah Mona , Rimadani Riski Ayu 
Published: January 2021

Malaria is one of the health problems in Indonesia. Kanujoso Hospital Djatiwibowo Balikpapan is a referral hospital for Balikpapan, Penajam Paser Utara and Paser. Kabupaten Penajam Paser Utara is the district with the highest incidence of malaria in East Kalimantan. In malaria there is a change of hematology one of them is thrombocytopenia. Several studies have suggested the involvement of thrombocytopenia with severe malaria events. The aim of this reasearch was to know the relations of degree of thrombocytopenia with severe malaria in malaria patients treated at Kanudjoso Djatiwibowo Hospital Balikpapan period 2013-2017.
This research was conducted by using analytic observational research method with cross sectional design. The sample was taken from the patient's medical record at Kanujoso Djatiwibowo Hospital Medical Record Installation for 2013-2017 period with the sample of 81 patients. The data were analyzed by using Fisher test. The results of this research showed that distribution malaria patients based on degree of thrombocytopenia were moderate, severe and mild respectively 41,98%; 40,79% and 17,28%. Severe malaria found in 13.58% patients. We found correlation between degree of thrombocytopenia with severe malaria with Fisfer test ((p=0,043). Our study found correlation between degree of thrombocytopenia with severe malaria in malaria patientspatients at Kanudjoso Djatiwibowo Hospital Balikpapan
Cyber Situational Awareness in Critical Infrastructure Protection
Authors: Pöyhönen Jouni , Rajamäki Jyri , Ruoslahti Harri , Lehto Martti 
Published: January 2021

The European Union promotes collaboration between authorities and the private sector, and the providers of the most critical services to society face security related obligations. In this paper, critical infrastructure is seen as a system of systems that can be subject to cyber-attacks and other disturbances. Situational awareness (SA) enhances preparations for and decision-making during assessed and unforeseen disruptive incidents, and promoting Cyber effective situational awareness (CSA) requires information sharing between the different interest groups. This research is constructive in nature, where innovative constructions developed as solutions for domain-specific real world problems, while the research question is: “How can cyber situational awareness protect critical infrastructures?” The Observe – Orient – Decide – Act (OODA) loop is examined as a way to promote collaboration towards a shared situational picture, awareness and understanding to meet challenges of forming CSA in relation to risk assessment (RA) and improving resilience. Three levels of organizational decision-making are examined in relation a five-layer cyber structure of an organization to provide a more comprehensive systems view of organizational cyber security. Successful, crisis-management efforts enable organizations to sustain and resume operations, minimize losses, and adapt to manage future incidents, as many critical infrastructures typically lack resilience and may easily lose essential functionality when hit by an adverse event. Situation awareness is the main prerequisite towards cyber security. Without situation awareness, it is impossible to systematically prevent, identify, and protect the system from cyber incidents.