bluuebunny/crossref_metadata_2025_split huggingface dataset:
Conservation threats from roadkill in the global road network
Authors: Grilo Clara , Borda‐de‐Água Luis , Beja Pedro , Goolsby Eric , Soanes Kylie , le Roux Aliza , Koroleva Elena , Ferreira Flávio Z. , Gagné Sara A. , Wang Yun , González‐Suárez Manuela 
Published: September 2021

AbstractAimThe road network is increasing globally but the consequences of roadkill on the viability of wildlife populations are largely unknown. We provide a framework that allows us to estimate how risk of extinction of local populations increases due to roadkill and to generate a global assessment that identifies which mammalian species are most vulnerable to roadkill and the areas where they occur.LocationGlobal.Time period1995–2015.Major taxa studiedTerrestrial mammals.MethodsWe introduce a framework to quantify the effect of roadkill on terrestrial mammals worldwide that includes three steps: (a) compilation of roadkill rates to estimate the fraction of a local population killed on the roads, (b) prediction of population risk of extinction based on observed roadkill rates (for a target group of species of conservation concern and non‐threatened species with high roadkill rates), and (c) global assessment of vulnerability to roadkill for 4,677 terrestrial mammalian species estimated using phylogenetic regression models that link extinction risk to demographic parameters.ResultsWe identified four populations among the 70 species in the target group that could become extinct in 50 years if observed roadkill levels persist in the study areas: maned wolf Chrysocyon brachyurus (Brazil), little spotted cat Leopardus tigrinus (Brazil), brown hyena Hyaena brunnea (Southern Africa) and leopard Panthera pardus (North India). The global assessment revealed roadkill as an added risk for 2.7% (n = 124) terrestrial mammals, including 83 species Threatened or Near Threatened. We identified regions of concern that have species vulnerable to roadkill with high road densities in areas of South Africa, central and Southeast Asia, and the Andes.Main conclusionsOur framework revealed populations of threatened species that require special attention and can be incorporated into management and planning strategies informing road managers and conservation agencies.
Government information disclosure and citizen coproduction during COVID‐19 in China
Authors: Wu Yiping , Xiao Hanyu , Yang Fang 
Published: September 2021

AbstractWhile information campaigns have been widely recognized as a pillar of public health crisis management and heightened by the current COVID‐19 pandemic, an insufficient number of studies have investigated the impact of information disclosure on influencing citizen cooperation crucial for emergency management. Focusing on generic information disclosure practices during the recovery period from January 19, 2020, to February 29, 2020, in China and by employing a difference‐in‐difference method, this study finds that information disclosure significantly enhanced citizen coproduction as measured by aggregated search queries of COVID‐19‐related information, and earlier disclosure yielded greater effect more quickly. Moreover, government capacity and citizens' trust in government at the local level significantly moderate the positive impact of information disclosure. This study uncovers the novel relationship between information disclosure and citizen coproduction during emergencies in the Chinese context.
Preference revelation games and strict cores of multiple‐type housing market problems
Authors: Feng Di , Klaus Bettina 
Published: September 2021

AbstractWe consider multiple‐type housing market problems as introduced by Moulin (1995) and study the relationship between strict strong Nash equilibria and the strict core (two solution concepts that are defined in terms of the absence of weak blocking coalitions). We prove that for lexicographically separable preferences, the set of all strict strong Nash equilibrium outcomes of each preference revelation game that is induced by a strictly core stable mechanism is a subset of the strict core, but not vice versa, that is, there are strict core allocations that cannot be implemented in strict strong Nash equilibrium. This result is extended to a more general set of preference domains that satisfy strict core non‐emptiness and a minimal preference domain richness assumption.
Effect of the extract from custard apple (Annona squamosa) leaves prepared with pulsed electric field‐assisted process on the diversity of microorganisms and shelf‐life of refrigerated squid rings
Authors: Olatunde Oladipupo Odunayo , Shiekh Khursheed Ahmad , Ma Lukai , Ying Xiaoguo , Zhang Bin , Benjakul Soottawat 
Published: September 2021

AbstractAntibacterial and antibiofilm properties of ethanolic custard apple leaf extract (CALE) prepared without and with pulsed electric field (PEF) assisted process (6 kV cm−1, 300 pulses, 142 kJ kg−1 for 5 min) (PEF‐CALE) were comparatively investigated. PEF‐CALE showed higher bacterial inhibition against Bacillus subtilis, Listeria monocytogenes, Escherichia coli, and Pseudomonas aeruginosa, compared to CALE. Antibiofilm properties of both extracts towards the aforementioned bacteria were augmented with increasing concentrations (P < 0.05). The impact of PEF‐CALE in extending the shelf‐life of squid rings (SQR) was also investigated. Based on the microbiological limit, the shelf‐life of refrigerated squid rings pretreated with 400 mg kg−1 PEF‐CALE was extended by more than 6 days when compared to the control. Pseudomonas lundensis, Pseudomonas fragi, and Shewanella baltica were the most abundant spoilage bacteria found in SQR. Overall, PEF‐CALE exhibited promising antimicrobial activities, which could serve as biopreservative agent for inhibiting bacterial growth in SQR during refrigerated storage.
Patient care standards for primary mitochondrial disease in Australia: an Australian adaptation of the Mitochondrial Medicine Society recommendations
Authors: Sue Carolyn M. , Balasubramaniam Shanti , Bratkovic Drago , Bonifant Catherine , Christodoulou John , Coman David , Crawley Karen , Edema‐Hildebrand Fabienne , Ellaway Carolyn , Ghaoui Roula , Kava Maina , Kearns Lisa S. , Lee Joy , Liang Christina , Mackey David A. , Murray Sean , Needham Merrilee , Rius Rocio , Russell Jacqui , Smith Nicholas J.C. , Thyagarajan Dominic , Wools Christine 
Published: September 2021

AbstractThis document provides consensus‐based recommendations for general physicians and primary care physicians who diagnose and manage patients with mitochondrial diseases (MD). It builds on previous international guidelines, with particular emphasis on clinical management in the Australian setting. This statement was prepared by a working group of medical practitioners, nurses and allied health professionals with clinical expertise and experience in managing Australian patients with MD. As new treatments and management plans emerge, these consensus‐based recommendations will continue to evolve, but current standards of care are summarised in this document.
Sepsis induces muscle atrophy by inhibiting proliferation and promoting apoptosis via PLK1‐AKT signalling
Authors: Cao Ying‐Ya , Wang Zhen , Yu Tao , Zhang Yuan , Wang Zhong‐Han , Lu Zi‐Meng , Lu Wei‐Hua , Yu Jian‐Bo 
Published: September 2021

AbstractSepsis and sepsis‐induced skeletal muscle atrophy are common in patients in intensive care units with high mortality, while the mechanisms are controversial and complicated. In the present study, the atrophy of skeletal muscle was evaluated in sepsis mouse model as well as the apoptosis of muscle fibres. Sepsis induced atrophy of skeletal muscle and apoptosis of myofibres in vivo and in vitro. In cell‐based in vitro experiments, lipopolysaccharide (LPS) stimulation also inhibited the proliferation of myoblasts. At the molecular level, the expression of polo‐like kinase 1 (PLK1) and phosphorylated protein kinase B (p‐AKT) was decreased. Overexpression of PLK1 partly rescued LPS‐induced apoptosis, proliferation suppression and atrophy in C2C12 cells. Furthermore, inhibiting the AKT pathway deteriorated LPS‐induced atrophy in PLK1‐overexpressing C2C12 myotubes. PLK1 was found to participate in regulating apoptosis and E3 ubiquitin ligase activity in C2C12 cells. Taken together, these results indicate that sepsis induces skeletal muscle atrophy by promoting apoptosis of muscle fibres and inhibiting proliferation of myoblasts via regulation of the PLK1‐AKT pathway. These findings enhance understanding of the mechanism of sepsis‐induced skeletal muscle atrophy.
Oridonin prevents oxidative stress‐induced endothelial injury via promoting Nrf‐2 pathway in ischaemic stroke
Authors: Li Lei , Cheng Shu‐Qi , Guo Wei , Cai Zhen‐Yu , Sun Yu‐Qin , Huang Xin‐Xin , Yang Jin , Ji Juan , Chen Ya‐Yun , Dong Yin‐Feng , Cheng Hong , Sun Xiu‐Lan 
Published: September 2021

AbstractOridonin, a natural diterpenoid compound extracted from a Chinese herb, has been proved to exert anti‐oxidative stress effects in various disease models. The aim of the present study was to investigate the protective effects of oridonin on oxidative stress‐induced endothelial injury in ischaemic stroke. We found oridonin repaired blood‐brain barrier (BBB) integrity presented with upregulation of tight junction proteins (TJ proteins) expression, inhibited the infiltration of periphery inflammatory cells and neuroinflammation and thereby reduced infarct volume in ischaemic stroke mice. Furthermore, our results showed that oridonin could protect against oxidative stress‐induced endothelial injury via promoting nuclear translocation of nuclear factor‐erythroid 2 related factor 2 (Nrf‐2). The specific mechanism could be the activation of AKT(Ser473)/GSK3β(Ser9)/Fyn signalling pathway. Our findings revealed the therapeutic effect and mechanism of oridonin in ischaemic stroke, which provided fundamental evidence for developing the extracted compound of Chinese herbal medicine into an innovative drug for ischaemic stroke treatment.
Differences in platelet‐rich plasma composition influence bone healing
Authors: Al‐Hamed Faez Saleh , Abu‐Nada Lina , Rodan Rania , Sarrigiannidis Stylianos , Ramirez‐Garcialuna Jose Luis , Moussa Hanan , Elkashty Osama , Gao Qiman , Basiri Tayebeh , Baca Laura , Torres Jesus , Rancan Lisa , Tran Simon D. , Lordkipanidzé Marie , Kaartinen Mari , Badran Zahi , Tamimi Faleh 
Published: September 2021

AbstractAimPlatelet‐rich plasma (PRP) is an autologous blood‐derived material that has been used to enhance bone regeneration. Clinical studies, however, reported inconsistent outcomes. This study aimed to assess the effect of changes in leucocyte and PRP (L‐PRP) composition on bone defect healing.Materials and MethodsL‐PRPs were prepared using different centrifugation methods and their regenerative potential was assessed in an in‐vivo rat model. Bilateral critical‐size tibial bone defects were created and filled with single‐spin L‐PRP, double‐spin L‐PRP, or filtered L‐PRP. Empty defects and defects treated with collagen scaffolds served as controls. Rats were euthanized after 2 weeks, and their tibias were collected and analysed using micro‐CT and histology.ResultsDouble‐spin L‐PRP contained higher concentrations of platelets than single‐spin L‐PRP and filtered L‐PRP. Filtration of single‐spin L‐PRP resulted in lower concentrations of minerals and metabolites. In vivo, double‐spin L‐PRP improved bone healing by significantly reducing the size of bone defects (1.08 ± 0.2 mm3) compared to single‐spin L‐PRP (1.42 ± 0.27 mm3) or filtered L‐PRP (1.38 ± 0.28 mm3). There were fewer mast cells, lymphocytes, and macrophages in defects treated with double‐spin L‐PRP than in those treated with single‐spin or filtered L‐PRP.ConclusionThe preparation method of L‐PRP affects their composition and potential to regenerate bone.
Comparison of three full‐mouth concepts for the non‐surgical treatment of stage III and IV periodontitis: A randomized controlled trial
Authors: Stein Jamal M. , Yekta‐Michael Sareh Said , Schittenhelm Florian , Reichert Stefan , Kupietz David , Dommisch Henrik , Kasaj Adrian , Wied Stephanie , Vela Octavia‐Carolina , Stratul Stefan‐Ioan 
Published: September 2021

AbstractAimTo evaluate the clinical efficacy of full‐mouth scaling (FMS), full‐mouth disinfection (FMD), and FMD with adjuvant erythritol air‐polishing (FMDAP) compared to quadrant‐wise debridement (Q‐SRP) in patients with periodontitis stage III/IV.MethodsIn this four‐arm parallel, prospective, randomized, controlled multi‐centre study, changes of pocket probing depths (PPDs), clinical attachment level (CAL), bleeding on probing (BOP), and proportion of closed pockets (PPD ≤4 mm without BOP) were evaluated at baseline and after 3 and 6 months.ResultsFrom 190 randomly participating patients, 172 were included in the final analysis. All groups showed significant (p < .05) improvements in all clinical parameters over 3 and 6 months. During the study period, FMDAP showed significantly higher reductions of mean PPD in teeth with moderate (PPD 4–6 mm) and deep (PPD > 6 mm) pockets and significantly increased proportions of pocket closure than Q‐SRP. Patients treated with FMD had significantly greater PPD reduction in deep pockets and a higher percentage of pocket closure after 3 months but not after 6 months compared to Q‐SRP. CAL and BOP changes did not significantly differ among all groups. Efficiency of treatment (time effort to gain one closed pocket) was significantly higher for FMDAP, FMD, and FMS compared to Q‐SRP (6.3, 8.5, 9.5 vs. 17.8 min per closed pocket; p < .05).ConclusionsAll treatment modalities were effective, without significant differences between full‐mouth approaches. FMDAP showed improved clinical outcomes over Q‐SRP for moderate and deep pockets after 6 months. Full‐mouth protocols were more time‐efficient than conventional Q‐SRP.Clinical SignificanceThe trial was registered in a clinical trial database (ClinicalTrials.gov: NCT03509233).
The value of using emotions in solution focused brief therapy
Authors: Walker Cecil R. , Froerer Adam S. , Gourlay‐Fernandez Natalia 
Published: September 2021

AbstractA commonly stated critique of Solution Focused Brief Therapy (SFBT) is a lack of attention to the client's emotional experience and the use of emotion as a mechanism for producing meaningful change. We review and define the current research regarding emotion, feeling, and affect and its value and relevance to the clinical application of SFBT. We also provide a brief history of the SFBT model and its documented emphasis on cognitive and behavioral change versus emotional change. In embodying the spirit of this approach for examining what works and doing more of it, we propose a next step of SFBT to more overtly attend to the emotional language of clients and to purposefully create emotional experiences with our clients. We demonstrate this by providing clinical examples for how SFBT practitioners can incorporate and build upon clients' emotional language to create emotionally‐changing experiences to more broadly and effectively co‐create long‐lasting change.
Talent in Distressed Firms: Investigating the Labor Costs of Financial Distress
Authors: BAGHAI RAMIN P. , SILVA RUI C. , THELL VIKTOR , VIG VIKRANT 
Published: September 2021

ABSTRACTThe importance of skilled labor and the inalienability of human capital expose firms to the risk of losing talent at critical times. Using Swedish microdata, we document that firms lose workers with the highest cognitive and noncognitive skills as they approach bankruptcy. In a quasi‐experiment, we confirm that financial distress drives these results: following a negative export shock caused by exogenous currency movements, talent abandons the firm, but only if the exporter is highly leveraged. Consistent with talent dependence being associated with higher labor costs of financial distress, firms that rely more on talent have more conservative capital structures.
Wear Behavior of Occlusal Splint Materials Manufactured By Various Methods: A Systematic Review
Authors: Grymak Anastasiia , Aarts John M. , Ma Sunyoung , Waddell J. Neil , Choi Joanne Jung Eun 
Published: September 2021

AbstractPurposeTo systematically review studies on various materials and methods used for wear testing of occlusal devices and their antagonists in vitro and in vivo.MethodsAn electronic search in OVID, Web of Science, PubMed and Scopus was conducted using the following terms (MeSH words) with any synonyms and closed terms: “Splint*” OR “occlusal splint*” OR “night guard” OR “occlusal device” OR “occlusal devices” OR “deprogrammer” OR “bite splint” OR “bite plane” OR “orthotic appliance*” OR “orthotic devices” AND “wear” OR “two‐body wear” OR “three‐body wear” OR “tooth wear” OR “wear measurement*” OR “wear behaviour” OR “wear behavior” OR “abrasion” AND “Polymethyl Methacrylate” OR “PMMA” OR “acrylic resin*” OR “dental material*” OR “dental enamel” OR “CAD” OR “CAM” OR “PEEK” OR “material* testing”. Database search was limited to English‐language publications and published between 2001 and 1st of September 2021. A further hand search was done to ensure all materials were captured.ResultsAfter the removal of duplicates, 115 studies were identified, and 11 were chosen for review. Studies showed that the lowest volumetric loss was observed in PEEK occlusal device materials, whereas heat‐cure, CAD‐milled, and 3D printed occlusal device materials had no significant difference in wear. Vacuum‐formed materials showed the highest wear among all groups. Testing parameters were found to be inconsistent across all studies.ConclusionThere is a need for standardization of in vitro and in vivo wear measurement and testing protocols as this study revealed a wide variety of testing protocols which potentially could influence the outcome. Polishing procedures are required for the material. Limited studies are available on 3D printed occlusal device materials and would therefore require further investigation, especially on printing build angles and settings. Further clinical studies would be advantageous to provide guidance on the selection of the best occlusal device material that would last the longest without remake.
Geographic spread of COVID‐19 and local economies: Heterogeneous effects by establishment size and industry
Authors: Kim Jun Sung , Kim Taehoon 
Published: September 2021

AbstractUsing province‐level establishments and employment data from the Korean Employment Insurance Database, this paper investigates how the regional spread of COVID‐19 affects local businesses and unemployment by establishment size and industry. We find that the number of small establishments declines substantially after the COVID‐19 pandemic through a decrease in new establishment creation and a surge in establishment closures. By contrast, large establishments are not affected significantly. Examining the numbers of unemployment benefits (UB) applicants, an indicator of unemployment, we find that the higher the rate of COVID‐19 confirmed cases in a province, the higher the number of UB applicants, regardless of their previous workplace size. Our analysis of employment insurance subscribers further confirms that the regional spread of COVID‐19 leads to a significant reduction in employment and job mobility in small establishments. Regarding industry heterogeneity in the COVID‐19 effects, we find that local COVID‐19 outbreaks affect local industries more through the reduction in establishment creation and new employment than through an increase in establishment closures. Industries that require face‐to‐face operations, such as lodging & restaurant, experience a substantial adverse impact in the early phase, and the impact also tends to last longer as COVID‐19 situations prolong.
Using in‐depth interviews to explore perceptions and opinions in men's skin care
Authors: Deubler Grace , Swaney‐Stueve Marianne , Koppel Kadri 
Published: September 2021

AbstractAffective and behavior‐based research on men's personal care products has not been abundant in published research. As the market for men's personal care products grows, specifically the skin care category, more research is required to better understand this consumer group. Eighteen in‐depth interviews with male consumers ages 18–49 were conducted with light and heavy users in two markets, Olathe, KS and Los Angeles, CA, to understand baseline information on men's perceptions, opinions, beliefs, and attitudes related to skin care. Key take‐aways included that men generally appreciate easy, fast skin care routines, use affordable and readily available products, and desire to maintain the look and/or health of their skin. Though some skin care claims can be appealing, many of the men were somewhat skeptical of typical marketing strategies. These findings help to show how brands are succeeding and failing at meeting male consumer expectations of skin care products and demonstrate the need for more exploration into this demographic.Practical ApplicationsThe available, published resources on men's skin care, and personal care as a whole, are few and far between. This work provides a qualitative example of personal care research in the men's skin care space. By presenting this primary research on how men talk about and interact with skin care products, sensory scientists will have a baseline understanding of the category before diving into more specific research questions. The manuscript provides a foundation on which future sensory and consumer research can build.