bluuebunny/crossref_metadata_2025_split huggingface dataset:
Population-based implementation of behavioral health detection and treatment into&nbsp;primary care:&nbsp;Early data from New York State
Authors: Bowen Deborah J. , Heald Ashley , LePoire Erin , Jones Amy , Gadbois Danielle , Russo Joan , Carruthers Jay 
Published: January 2021

Abstract
Background The Collaborative Care Model is a well-established, evidence-based approach to treating depression and other common behavioral health conditions in primary care settings. Despite a robust evidence base, real world implementation of Collaborative Care has been limited and very slow. The goal of this analysis is to better understand the relationship between training, technical assistance, and implementation in the largest state-led Collaborative Care program in the nation—the New York State Collaborative Care Medicaid Program.Data are presented using the RE-AIM model, examining the proportion of clinics in each of the model’s five stages from 2014 to 2019.MethodsWe used the RE-AIM model to shape our data presentation, focusing on the proportion of clinics moving into each of the five stages of this model over the years of implementation. Data sources included: a New York State Office of Mental Health clinic tracking database, billing applications, quarterly reports, and Medicaid claims.ResultsA total lf 84% of clinics with which OMH had an initial contact [n = 611clinics (377 FQHCs and 234 non-FQHCs)] received some form of training and technical assistance. 51% went on to complete a billing application, 41% reported quarterly data at least once, and 20% were able to successfully bill Medicaid. 79% of clinics that reported data maintained Collaborative Care for one year or more. The receipt of any training and technical assistance was significantly associated with our implementation indices: (completed billing application, data reporting, billing Medicaid, and maintaining Collaborative Care). The average percent of patient improvement for depression and anxiety across 155 clinics that had at least one quarter of data was 44.81%. Training and technical assistance source (Office of Mental Health, another source, or both) and intensity (high/low) were significantly related to implementation indices and were observed in FQHC versus non-FQHC samples.ConclusionsOffering Collaborative Care training and technical assistance, particularly high intensity training and technical assistance, increases the likelihood of implementation. Other state-wide organizations might consider the provision of training and technical assistance when assisting clinics to implement Collaborative Care.
Contraceptive use among sexually active female adolescent in Ethiopia:Trends and determinants insight from national demographic and health survey
Authors: Olika Alemi Kebede , Kitila Sena Belina , Terfa Yonas Biratu , Olika Ayantu Kebede 
Published: January 2021

Abstract
Background: Sexual and reproductive health and right of young people is a global priority as the reproductive choices made by them have a massive impact on their health and wellbeing, education and economy. Teenage pregnancy is a public health issue and a demographic challenge in Ethiopia. The use of contraceptive method is a most effective way for sexually active adolescent to prevent pregnancy and its related complication. However, little is known about the trends in contraceptive use and its determinant among adolescent girls in Ethiopia. Therefore, this study was designed to examine the trends and correlates of contraceptive use among sexually active girls aged 15-19 years in Ethiopia by using Ethiopian demographic and health survey data. Methods: Four Ethiopian demographic and health survey data were used to examine trends of contraceptive methods use. To identify factors associated with contraceptive use, the 2016 Ethiopian demographic and health survey data were used. The data was accessed from the demographic and health survey program database and data for sexually active adolescent girls were extracted. Data analysis was done using SPSS version 21. Data were weighted for analysis. Descriptive analysis was used to describe independent variables of the study. Multivariable logistic regression model was used to identify factors associated with contraceptive use.Results: Contraceptive method use was increased significantly from 6.9% in 2000 to 39.6% in 2016 among sexually active adolescent girls in Ethiopia. The odds of contraceptive use were lower among female adolescent who had no formal education (AOR= 0.044; 95% CI= 0.008–0.231) and attended primary education (AOR= 0.101; 95% CI= 0.024–0.414). But the odds of contraceptive methods use were higher among adolescents in rich wealth status (AOR= 3.662; 95% CI =1.353–9.913) and those who were told about family planning during their health facility visits (AOR= 3.115; 95% CI= 1.385–7.007).Conclusion: Contraceptive method use was increased significantly among sexually active adolescent girls in Ethiopia in the year 2000 to 2016. Wealth status, educational status and information about family planning during their health facility visits were factors associated with contraceptive use. Improving economic and educational status of young women may help in improving contraceptive use in Ethiopia.
Digital learning designs in physiotherapy education: A systematic review and meta-analysis.
Authors: Ødegaard Nina Bjerketveit , Myrhaug Hilde Tinderholt , Dahl-Michelsen Tone , Røe Yngve 
Published: January 2021

Abstract
Background: Digital learning designs have the potential to support teaching and learning within higher education. However, the research on digital learning designs within physiotherapy education is limited. This study aims to identify and investigate the effectiveness of digital learning designs in physiotherapy education.Methods: The study was designed as a systematic review and meta-analysis of randomized and non-randomized trials. A search of eight databases on digital learning designs and technology was conducted. Study selection, methodology and quality assessment were performed independently by three reviewers. The included studies were mapped according to the types of digital interventions and studies. For similar interventions, the learning effects were calculated using meta-analyses. Results: Altogether, 22 studies were included in the review (17 randomized controlled trials and five cohort studies). A blended learning design was used in 21 studies, a flipped classroom model in five and a distance learning design in one. Altogether, 10 of the 22 articles were included in meta-analyses, which showed statistically significant effects for flipped classrooms on knowledge acquisition (standardized mean difference [SMD]: 0.41; 95% confidence interval [CI]: 0.20, 0.62), for interactive websites or applications (apps) on practical skills (SMD: 1.07; 95% CI: 0.71,1.43) and for students self-produced videos on a practical skill in a cervical spine scenario (SMD: 0.49; 95% CI: 0.06, 0.93). Overall, the effects indicated that blended learning designs are equally as or more effective than traditional classroom teaching to achieve learning outcomes. Distance learning showed no significant differences compared to traditional classroom teaching.Conclusions: The current findings from physiotherapy education indicate that digital learning designs in the form of blended learning and distance learning were equally or more effective compared to traditional teaching. The meta-analysis revealed a significant effect on student learning in favour of flipped classrooms and interactive websites/apps. However, these results must be confirmed in larger controlled trials. Further, research should investigate how digital learning designs can facilitate students’ learning of practical skills and behaviour, learning retention and approaches to studying as well as references for teaching and learning in digital learning environments.
Medication Adherence Support of an In-home Electronic Medication Dispensing System for Individuals living with Chronic Conditions: A Pilot Randomized Controlled Trial
Authors: Arain Mubashir , Ahmad Armghan , Chiu Venus , Kembel Lorena 
Published: January 2021

Abstract
Background: Medication adherence is challenging for older adults due to factors such as the number of medications, dosing schedule, and the duration of drug therapy. The objective of this study was to examine the effectiveness of an in-home electronic medication dispensing system (MDS) on improving medication adherence and health perception in older adults with chronic conditions. Methods: A pilot Randomized Controlled Trial (RCT) was conducted using a two-arm parallel assignment model. The intervention group used an MDS as their medication management method. The control group continued to use their current methods of medication management. Block randomization was used to assign participants into the intervention or control group. The inclusion criteria included 1) English speaking 2) age 50 and over 3) diagnosed with one or more chronic condition(s) 4) currently taking five or more oral medications 5) City of Calgary resident. Participants were recruited from a primary care clinic in Alberta, Canada. The study was open label where knowledge about group assigned to participants after randomization was not withheld. Medication adherence was captured over a continuous, six-month period and analyzed using Intention-to-Treat (ITT) analysis. Results: A total of 91 participants were assessed for eligibility and 50 were randomized into the two groups. The number of participants analyzed for ITT was 23 and 25 in the intervention and control group, respectively. Most of the demographic characteristics were comparable in the two groups except mean age of the intervention group, which was higher compared to the control group (63.96±7.86 versus 59.52±5.93, p-value=0.03). The average recorded adherence over 26 weeks was significantly higher in the intervention group than the control group (98.35%±2.15% versus 91.17%±9.76%, p<0.01). The self-rated medication adherence in the intervention group also showed a significant increase from baseline to 6-month (7.63±1.63 versus 9.13±0.81, p<0.01). The control group showed a non-significant increase (7.20±1.74 versus 8.27±2.09, p=0.07). Conclusion: MDS can be an effective, long-term solution to medication non-adherence in older adults experiencing chronic conditions and taking multiple medications. The technology induces better consistency and improvement in medication taking behaviour than simple, non-technological intervention. Trial Registration: Registered with ClinicalTrials.gov on April 09, 2020 with identifier NCT04339296.
Lipid Metabolism and Relevant Disorders to Female Reproductive Health
Authors: Ferrer María José , Silva Aimé Florencia , Abruzzese Giselle Adriana , Velázquez Mariela Edith , Motta Alicia Beatriz 
Published: January 2021

Background:
Lipids are essential components of cells that participate in
metabolic and endocrine regulation and reproductive functions. The main organs where
lipid regulation takes place are the liver and adipose tissue. Besides, when each tissue-
specific action cannot be exerted, it could lead to several endocrine-metabolic disorders
closely related to PCOS, such as non-alcoholic fatty liver disease (NAFLD) and obesity.

Objective:
This work aims to discuss the impact of lipid alterations on metabolic and reproductive
health. Therefore, this review focus on the importance of carrying out an integrated
study of the molecular pathways affected in PCOS for developing target therapies.

Results:
Lipids play a major role in PCOS pathogenesis. In this regard, failures in lipid
regulation, synthesis, and/or homeostasis contribute to metabolic and reproductive abnormalities,
such as those seen in PCOS. Several lipid pathways and regulators are altered in
this pathology, leading to dysfunctions that worsen reproductive functions. Therefore,
there are several treatments to manage dyslipidemias. Non-pharmacological therapies are
considered a first-line treatment being the pharmacological treatments a second-line option.

Conclusion:
The best treatment to improve the lipid profile is a lifestyle intervention, a combination of hypocaloric diet and
exercise. Regarding pharmacological therapies, a combination of fibrate and statins would be the most recommended drugs.
Still, in PCOS women, treatment with metformin or TZDs not only modulates the lipid metabolism, but also improves the
ovulation. Also, metformin with lifestyle interventions has positive effects on the metabolic and reproductive features of
PCOS patients.
Self-supported Hierarchical Nanoporous Cu/Mo@MoOx Hybrid Electrodes as Robust Nonprecious Electrocatalysts for High-efficiency Hydrogen Evolution
Authors: Han Li-Ping , Shi Hang , Yao Rui-Qi , Wan Wu-Bin , Wen Zi , Lang Xing-You , Jiang Qing 
Published: January 2021

Background:
The hydrogen evolution reaction is a crucial step in electrochemical water
splitting to generate molecular hydrogen with high purity, but it usually suffers from a sluggish reaction
kinetics in alkaline media because of additional water dissociation and/or improper adsorption
energy of reactive hydrogen intermediates. It is desirable to design highly active and robust nonprecious
electrocatalysts as alternatives to state-of-the-art commercially available Pt/C catalysts for
large-scale hydrogen production via water-alkali electrolysis.

Methods:
We developed monolithic nanoporous hybrid electrodes composed of electroactive
Mo@MoOx nanoparticles, which are seamlessly integrated on hierarchical nanoporous Cu scaffold
(Cu/Mo@MoOx) by making use of a spontaneous phase separation of Mo nanoparticles and subsequently,
self-grown MoOx in chemical dealloying.

Results:
Owing to the unique monolithic electrode architecture, in which the constituent Mo@MoOx
nanoparticles work as electroactive sites and the hierarchical nanoporous Cu skeleton serves as fast
electron-transfer and mass-transport pathways, the monolithic nanoporous Cu/Mo@MoOx hybrid
electrode exhibits superior electrocatalysis in 1 M KOH, with a low Tafel slope of 66 mV dec−1 and
outstanding stability. It only takes them ~185 mV overpotential to reach −400 mA cm−2, ~150 mV
lower than that of nanoporous Cu supported Pt/C.

Conclusion:
The outstanding electrochemical performance and excellent structural stability make
nanoporous Cu/Mo@MoOx electrodes attractive alternatives to Pt/C catalysts in alkaline-based devices.
Ratiometric and Selective Fluorescent Nanosensor for the Detection of Glucose
Authors: Qi Shengda 
Published: January 2021

Background and Methods:
Dual-emission fluorescent nanosensor for the detection of
glucose has been developed by simply mixing the blue-emission C-dots (CDs) with red-emission
glutathione modified CdTe QDs.

Results and Discussion:
The ratiometric fluorescence system exhibits dual emission peaks at 442
nm and 600 nm under a single excitation wavelength (365 nm). Due to the strong quenching effect
of hydrogen peroxide to the quantum dots, the fluorescence of the QDs in the nanocomposite
system could be selectively quenched by H2O2, while the fluorescence of the CDs remained
constant, resulting in a distinguishable fluorescence color evolution (from red to blue) of the
nanosensor which could be visible through naked eye. When this nanosensor was mixed with
glucose oxidase, H2O2 can be produced by the enzyme catalysis reaction, which could quench the
fluorescent intensity of QDs. So this system can be used to detect glucose. The limit of detection of
this present method was as low as 0.1 μM.

Conclusion:
The result for glucose was satisfying, suggesting its potential application for glucose
sensing.
Stroke and COVID-19 Pandemic: The Dilemma
Authors: Mohamed Sherif , El-Mohsen Seham Abd , El-Hassan Osama Abo , AbdelHaffez Azza , El-Aziz Nashwa Abd 
Published: January 2021

Background:
While the COVID-19 pandemic affected more than thirty million people
world-wide, still the true link between COVID-19 and the incidence of stroke remains to be elucidated.

Methods:
Herein, we briefly discuss virology of COVID-19 and approaches for diagnosis and treatment
of COVID-19 patients, as well as the mechanisms that link stroke and COVID-19.

Results:
Many pathophysiologic and immunologic mechanisms have been implicated in stroke occurring
among patients with COVID-19. COVID-19 pandemic has, in different ways, negative impacts
on the care of stroke patients world-wide, and still, neurologists have to face many challenges
to improve the care of stroke patients during such crisis.

Conclusions:
Although the control of the COVID-19 is of crucial importance, at the same time, the
management of stroke must not be neglected. Therefore, preserving care for critical conditions
such as stroke, and providing strategies to ensure this continues, have a priority even during the crisis.
Till vaccine is available for COVID-19, strategies for rapid diagnosis and those for treating patients
with that disease are evolving. Further studies are warranted.
COLATERAL BLOOD FLOW AT THROMBOSIS IN THE FEMORAL VENOUS COLLECTOR
Authors: Popovich Y. М. , Rusin V. V. , Kochmarh О. М. , Shitev А. І. 
Published: January 2021

Anatomical features of collateral circulation of a hip influence on the severity of a clinical picture at deep thromboses and play a role in the prevention of complications. This necessitates the assessment of collateral blood flow.
The aim of research: to evaluate the compensatory possibilities of the collateral blood flow in the femoral venous collector in the acute venous thrombosis.
Methods. The analysisis made of results examination and treatment of 790 patients with the acute thrombosis in the vena cava inferior system and being treated at the Transcarpathian Regional Clinical Hospital named after A. Novak and the Transcarpathian Regional Clinical Oncology Center during 2006–2016. The laboratory methods and the instrumental ones (ultrasound duplex scanning, X-ray phlebography, computed tomography, radionuclide flebo scintigraphy and ultrasound scanning of heart) were used for investigation of patients,
Results of research. Deep vein thrombosis in the popliteal-femoral segments was observed in 322 (40.8%) of 790 patients. At the occlusion of the popliteal-femoral segments in the collateral blood flow take part the next vessels: superficial (large subcutaneous vein, small subcutaneous vein, posterior cutaneous femoral vein) and deep (deep femoral vein, vein-satellites of the main arteries, popliteal-femoral-sciaticpath, v. articularis genusuprema, vv. comitans n. ischiadici and abnormal femoral collateral), which quickly off set violations.
At the spread of thrombosis to general femoral vein, the clinical picture of the disease becomes more pronounced, due to the exclusion from the blood flow of deep femoral vein and most superficial venous collaterals (posterior cutaneous femoral vein and large subcutaneous vein), which leads to a sharp decompensation of venous outflow.
Conclusions. At the deep vein thrombosis in the popliteal-femoral segment the venouscollaterals, whichin 98.4% of cases occur secondarily, quickly compensate for hemodynamicdisorders, but at progression of thrombosis and exclusion of deep femoral and large subcutaneous veins in popliteal-femoral segments the decompensation of venous blood flow rapidly.
Thrombosis of deep veins in the popliteal-femoral segment occurs secondarily, due to the spread of thrombotic masses from the tibial veins. The jugular vein share the source of thrombosis in only 1.6% of patients.
At occlusion of a popliteal-femoral venous segment in collateral blood flow the following vessels participate: superficial (LSV, SSV, a back cutaneousvein of a hip) and deep (DFV, veins-satellites of the main arteries, popliteal-femoral-sciatic way, v. Articularis us vv. comitans n. Ischiadici and abnormal femoral collaterals), which quickly eliminate hemodynamic disturbancesin the popliteal-wall segment.
The most pronounced clinical symptoms of deep vein thrombosis in the popliteal-femoral segment are observed when excluding from the collateral blood flow of the deep femoral and great saphenous veins.
Lezers aan het woord (4/5-2016)
Authors: Devriese Luc 
Published: January 2021

Gentse winkels - De eerste grote zilveren munten in Vlaanderen 1269-1322 - Rijke Gentse families in de 19de eeuw - Archeologisch onderzoek in Gent, 2015 (zie Heel Nummer pp 317-319)
De Willempoort in Gent - weerstander Jules Laforce - café Rembrandt in de Vlaanderenstraat - Reytbilck en Mostgaverbilck in Drongen - Meersstraat (nu Sint-Denijslaan) en het vroegereSchoonmeersbrugje - Ottergemhoeve ligging - Rietgracht als straatnaam - Leebeek in Sint-Pieters-Aaigem, relatie tot de Rietgracht - Postcode 9000 en de grenzen van Gent - Ontstaan van de Gentse Feesten - In ‘t Gentsch (hoe het te schrijven).
IN MEMORIAM: ERIK DE KEUKELEIRE
'Zwart hooi, verbrande oppers'. Hugo Claus en de gevaren van een wezenlijk-Vlaams landschap
Authors: Fuhrmann Aragorn 
Published: January 2021

Uitgangspunt van deze bijdrage vormt een schilderijtje dat de jonge Hugo Claus vervaardigde in 1945, minder dan een jaar nadat hij met zijn familie zijn thuisstad Kortrijk was ontvlucht om aan de straatrepressie te ontkomen. Net zoals in vele andere schilderijen en gedichten van eerst geradicaliseerde en vervolgens gedesillusioneerde Vlaams-nationalisten die in de directe nasleep van de repressie tot stand kwamen, wordt in dit traditioneel-rurale tafereel een eeuwig vruchtbaar Vlaanderen opgeroepen dat – zo wordt in deze bijdrage betoogd – als een symbolische compensatie functioneert voor het uitblijven van een eigen natie. Pas in 1952, wanneer hij zijn Oostakkerse gedichten (1955) begint te schrijven, onderneemt Claus voor het eerst een volwaardige, zij het nog vrij intuïtieve poging om dergelijke discursieve landschappen en de politieke gevaren ervan op losse schroeven te zetten. Om tot een goed begrip van deze gedichten te komen, wordt in deze bijdrage daarom eerst een beeld geschetst van de beladen literaire en schilderkundige traditie waarin het wezenlijk-Vlaamse landschap een topos vormt en waartegen Claus zich later zal verzetten. Inzichten uit de internationale theorievorming rond landschap dienen daarbij als inspiratie voor een discours-analytische lezing van zowel deze traditie als Claus’ kritiek erop.__________
‘Black hay, burned ricks [Zwart hooi, verbrande oppers]’. Hugo Claus and the dangers of an essentially Flemish landscape
The starting point of this paper is a painting made by the sixteen-year old Hugo Claus in 1945, less than a year after he and his family had fled from their hometown Kortrijk in order to escape from the postwar street violence. As in so many other paintings and poems depicted by radicalised Flemish nationalists who became disillusioned after the war, this traditionalrural picture evokes a perpetually fertile Flanders which – as is argued in this paper – functions as a symbolic compensation for the enduring absence of a proper nation. It is only in 1952, when he starts writing his De Oostakkerse gedichten (1952), that Claus attempts to perturb such discursive landscapes and their inherent political dangers in a fully-fledged, yet rather intuitive, manner. To favour a good understanding of these poems, this paper first elaborates on the image of the controversial literary and painterly tradition criticised by Claus in which the essential-Flemish landscape functions as a topos. Observations from international landscape theories serve as a guideline for a discourse-analytic lecture of this tradition and Claus’s critique.