bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of dexamethasone on quality of recovery and analgesic consumption after valvular cardiac surgery
Authors: Abdelrazek Amr N. , Elaziz Mennatallah M.A. , Ali Nagy S. , Mohamed Omyma S. 
Published: April 2021

Background
Many therapeutic strategies have been developed to attenuate the inflammatory reaction to cardiopulmonary bypass and thereby enhance fast-track recovery of the cardiac surgical patient. The aim of the study was to determine the effect of small versus intermediate dose of dexamethasone on patient-perceived quality-of-recovery (QoR) scores in valvular replacement cardiac surgical patients and postoperative analgesic consumption.

Patients and methods
After obtaining local ethics committee approval and wr tten consent, 60 patients with American Society of Anesthesiologists physical state II and III, aged 16–60 years underwent elective valvular replacement surgery. Those patients were randomly divided into three equal groups, with 20 patients each. Group S received small-dose dexamethasone (0.1 mg/kg) in a total volume of 5-ml saline, group I received intermediate-dose dexamethasone (0.2 mg/kg), and group C received placebo (5-ml saline).

Results
Our results concerned with QoR-40 score showed significant statistical difference between the three groups in the dimensions of emotions, physical comfort, psychological support, and pain but not in the dimension of physical independence, in favor of dexamethasone groups.

Conclusion
Postoperative QoR-40 scores in the dimensions of emotional state, physical comfort, psychological support, and pain were all improved in the dexamethasone groups compared with the control group. The intermediate dose (0.2 mg/kg) of dexamethasone was better than the small dose (0.1 mg/kg) in the dimension of pain on postoperative day (POD) 1 and POD 2, whereas it was better on POD 3 and POD 2 in the dimensions of psychological support and physical comfort, respectively.
Short-axis/out-of-plane versus long-axis/in-plane ultrasound-guided central venous catheter placement by inexperienced trainees
Authors: Elsayed Mohamed , Hassn Ali Mohmd 
Published: April 2021

Background
Ultrasound (US) guidance for central venous catheter (CVC) placement is considered gold standard in localization and cannulation, making the procedure safer with less complications.

Objective
To compare the short-axis/out-of-plane (SAX) with the long-axis/in-plane (LAX) technique for US-guided CVC insertion in internal jugular vein in intensive care practice regarding safety and efficacy.

Patients and methods
A prospective randomized trial was conducted in Zagazig University Hospitals, from October 2017 to October 2018. All were randomized into one of two groups according to US guidance technique: SAX technique (group S), including 116 patients, and the LAX technique (group L), including 116 patients, for US-guided CVC insertion in internal jugular vein. The primary outcome was first-attempt success rate of both the SAX and LAX approaches for US-guided vascular catheterization. The secondary outcomes were total success rate, which was defined as successful venous cannulation without complication; cannulation times calculated in seconds; the number of attempts; and complications (hematoma and arterial puncture).

Results
US-guided venous cannulation was successful without complications in 115 (99.14%) patients. Venous access time, catheterization time, and US imaging time were significantly lower in the group S than in the group L (P<0.05). Complications in both groups had no significant difference. Hematoma formation was evident in one patient in group L. Multiple puncture was more in LAX group, with no significant difference.
Evaluation of patient satisfaction and masticatory performance in mandible single implant-assisted overdenture
Authors: Kashyap Swati , Mittal Sanjeev , Sharma Navneet , Sukhija Urvashi , Kamra Mohit , Gupta Nitika 
Published: April 2021

Objectives:
Many authors’ have advocated a minimum of two implants to support a mandibular overdenture, but financial restraints specifically among the geriatric population in developing countries made this treatment plan economically difficult. Hence, this study was planned to assess the symphyseal (midline) single implant-assisted complete overdenture for patient satisfaction and masticatory performance.

Materials and Methods:
In this clinical study, 12 edentulous first-time denture wearers underwent placement of a single implant in the mandibular symphyseal region. After 1 week, new complete dentures were fabricated and delivered to the patients. Post 3 months, the denture was fixed with a nylon cap-ball attachment to the anchor implant. Patients were questioned about comparison in the level of satisfaction and complaint before loading the implant (control group) and after 1 week, 1 month, and 3 months. The implant-assisted overdenture was fabricated with the help of a questionnaire. Masticatory performance was calculated with the help of a bite force measuring device at the same time intervals. SPSS 17.0 statistical software was used to analyze the data.

Results:
It was found that single implant anchorage of the mandibular complete denture resulted in a significant increase (P < 0.05) in patient's subjective satisfaction and a decrease (P < 0.05) in complaints at the end of 3 months. There was a significant (P < 0.01) increase in bite force in implant overdenture after 3 months (5.459 kgf) as compared to that of the complete denture (3.406 kgf).

Conclusion:
Single implant-assisted overdenture can be an appropriate treatment modality to treat edentulousness in the geriatric population. It insinuates the remarkable improvement of prosthesis function and oral comfort with minor surgical procedures.
Nanoteknoloji ve Nanomimarlık
Authors: SARI TEKİN Cansu , SARI ÇETİN Aysu 
Published: April 2021

Uygulama alanlarının çeşitliliğinden dolayı ülkeler için önemli bir yere sahip olan nanoteknoloji 21. Yüzyılın en önemli gelişmesi arasında yer almaktadır ve milyarlarca dolar yatırım yapılmaktadır. 1 ile 100 nanometre boyutundaki yapıların yüksek performanslı bir amaca hizmet etmesi için tasarlanması ve kullanılmasına nanoteknoloji denilmektedir. Malzeme bilimi alanında kullanılmasının yanı sıra gıda, tekstil, eczacılık, tıp, fizik, kimya, biyoloji, elektronik, gibi pek çok alanda uygulanmasıyla yenilikler getiren nanoteknoloji mimarlık alanında da yapı sektöründe birçok konuda gelişmeler göstermektedir. Nanomimarlık bağlamında mekanın dışında ve içerisinde kullanılan malzemelerde sağlam, kaliteli, uygun ve hafif yapıların ortaya çıkmasında nanoteknolojinin etkisi hızla devam etmektedir. Kullanım alanları arasında üretim tekniklerinde, yüzeylerin kendini temizleyebilme özelliği, ısı yalıtım malzemeleri, nanokompozit malzeme, aydınlatma, havalandırma ve hava kalitesini arttıran malzemeler, beton yüzeyler, yangın korunumu, lotus etkisi ile boya malzemeleri, kaplama uygulama yüzeyleri, fotovoltaik paneller, yansıma önleyici malzemeler ve enerji gibi alanlarda sürdürülebilir yapılarda kullanılmaktadır. Dünya üzerinde nanoteknolojinin kullanım alanının geniş olduğu görülmektedir.
Siyah Kuğu Pandeminin Türk Firmaları Üzerine Etkileri ve Yakın Gelecekte Firmalarin Yüzyüze Satışa Yönelik Öngörüleri
Authors: UNAL KESTANE Serpil 
Published: April 2021

Hayatın her yönünü değişik şekillerde etkileyen ve siyah kuğu olarak adlandırabileceğimiz PANDEMİ, özellikle ekonomik yaşamın temel taşı olan firmaları da farklı şekillerde etkilemiştir. Bu döneme özgü bazı kısıtlamalar yüz yüze satışları olumsuz yönde etkilemiş, tüketici ve firmaları dijital platformlara sevk etmiştir.
Bu araştırmanın da ana amacı pandeminin firmaları ne şekilde etkilediği ve firmaların bu özel koşullardan kendileri adına ne gibi dersler çıkardığının belirlenmesidir. Ayrıca, kısıtlamalar nedeniyle aksayan yüzyüze satış ve bu dönemde firmaların satış elemanlarından beklentilerinin neler olduğunun belirlenmesi de araştırmanın alt amaçları arasındadır.
Araştırmada nitel araştırma tekniklerinden “görüşme tekniği” kullanılmış ve 48 firma ile yüzyüze ya da çevrimiçi olarak görüşmeler gerçekleştirilmiştir. Görüşmelerde firmalara “yüz yüze satış, satış elemanlarından beklentiler ve pandemi” ile ilgili olarak yaklaşık 11 adet soru yöneltilmiştir. Araştırma sonucunda firmaların, dijital satışa yönelik yatırımlarını büyük ölçüde artırdığı ve özellikle sosyal medya konusunda uzman olan, e ticareti bilen satış elemanlarına daha fazla ihtiyaç duydukları görülmüştür. Ancak firmalar, yüz yüze satışın yerini hiçbir satış tekniğinin dolduramayacağı ve yeni düzende de yüz yüze satışın asla sona ermeyeceği konusunda hemfikirdirler.
Effect of Body Position on Oxygenation and Hemodynamic Status among Patients with Traumatic Brain Injury
Authors: Ismail Abdullah Sh. , Mohammad Sahar Y. , Mourad Amira H. 
Published: April 2021

Context: Positioning is one of the most frequently performed nursing activities in the critical care unit. It is often providing a central pivotal focus for planning other nursing activities. Therapeutic positioning of the patient's head, different degrees of the head of the bed elevation has been suggested as a low-cost and simple approach to preventing secondary brain injury.
Aim: determine the effect of body position on oxygenation and hemodynamic status among patients with traumatic brain injury.
Methods: Quasi-experiments (single group pre/posttest design). The study was conducted in the Critical Care Units in El-Mansoura general hospital at El-Mansoura city. A purposive sample of (67) adult patients diagnosed with traumatic brain injuries was recruited in this study. A structured socio-demographic interview questionnaire, patients’ medical records to elicit clinical variables and record cardiorespiratory assessment findings, Glasgow Coma Scale, and Richmond Agitation Sedation Scale were used to either include or exclude the patient according to the study criteria.
Results: There was a significant increase in oxygen saturation in post right lateral position from (94.93 ± 1.25 to 95.37 ± 1.17) and the semi fowler position from (95.37 ± 1.17 to 97.31 ± 11.13) compared to pre-positioning. The hemodynamic parameters (heart rate, respiratory rate, systolic blood pressure, diastolic blood pressure, and mean arterial pressure) were significantly decreased in the post-semi-fowler position and then right lateral position compared to pre. Besides, the CVP is significantly increased in the semi-fowler position.
Conclusion: Oxygen saturation and all hemodynamic parameters were significantly improved compared to their normal range in post-semi-fowler position, then right lateral position. Develop nursing practice protocol for critical care nurses to position patients at the semi-fowler position after traumatic brain injury can improve oxygenation and hemodynamic parameters. Moreover, further studies should be carried out to assess the effect of other body positions in other medical conditions.
University ESL Instructors’ Reflections on the Use of Blended Learning in their Classrooms
Authors: Ibrahim Said , Ismail Fauziah 
Published: April 2021

Blended learning has been adopted in many universities worldwide since it combines the advantages of both online learning and face to face instruction. In this paper, the researcher reports on the quantitative segment of a mixed-methods case study that was conducted in a public university in Malaysia with the aim of investigating the ESL instructors’ reflections on the implementation of blended learning in their English language classrooms. More specifically, the researcher was interested in identifying the factors that enhance the implementation of blended learning and the challenges that seem to hinder an effective blended learning environment. The quantitative data of the study were collected by a survey questionnaire, which was distributed to at least 30 English language instructors. Nineteen instructors responded to the questionnaire, and the data were analyzed by descriptive statistics via the statistical package for social science (SPSS). Findings show that while experience with technology and positive attitudes towards technology were identified as main factors enhancing the implementation of blended learning; workload and technological infrastructure were found to be the major challenges. The study signifies the need to address technology and workload related issues in order to effectively implement blended learning to promote ELT at tertiary level.
Daniel Foliard (2020) - Combattre, punir, photographier. Empires coloniaux, 1890-1914
Authors: Gendry Thaïs 
Published: April 2021

Recensé : Foliard Daniel, Combattre, punir, photographier. Empires coloniaux, 1890-1914, Paris, La Découverte, 2020, 454 p.
Dose dependent effect of silver nitrate on enhanced production of gymnemic acid in cell suspension cultures of Gymnemasylvestre R. Br
Authors: Rajashekar Jarubandi , Kumar Vadlapudi , Poornima DittekoppaVijendra , Hari Gajula , Sannabommaji Torankumar , Raghuramulu D 
Published: April 2021

Introduction and Aim: Gymnemasylvestre is rich source of triterpenoid saponins and is popularly known for its anti-diabetic potential. Gymnemic acid is chiefly responsible for its therapeutic potential. In fact, gymnemic acid is a group of compounds known as gymnemagenin (oleanane group) and other related compounds are gymnemasides (dammaranes). Despite of its immense medicinal importance, very few studies were conducted for enhanced gymnemic acid production. The present study undertaken for the enhanced gymnemic acid production using silver nitrate (AgNO3) as effective elicitor and its influence on other culture parameters.
Materials and Methods:Callus culture was initiated for cell suspension culture establishment and is used to study the elicitor effect. Different doses of AgNO3 used at varied culture periods and its mediated effect on growth index, pH, EC and MDA content was conducted. Gymnemic acid production was estimated by HPLC.

Results:Cell growth was positively influenced by AgNO3 with concomitant change in pH and EC of the medium. Apparent rise in MDA content in response to increased AgNO3 dosage was observed and is positively correlated with enhanced gymnemic acid production. Dose dependent effect of AgNO3 was observed at different culture periods used under study.
Conclusion: Substantial improvements of gymnemic acid produced in response to AgNO3 at 100µM dosage can be used for its enhanced production at industrial scale. It also offers opportunities for studying elicitor influence on other parameters for gymnemic acid production
Identification of novel potent pancreatic lipase inhibitors from Ficus racemosa
Authors: Vijaya Anand A. , Bharathi V. , Bupesh G. , Lakshmi Jaya , Meenakshi Sundaram K. , Saradhadevi . M. 
Published: April 2021

Introduction and Aim: Obesity is a disorder of lipid metabolism and continues to be a global problem, ranking fifth for deaths worldwide. It is considered to be main reason for a number of physiological changes that resulting in many metabolic disorders such as cardiovascular diseases, diabetes, musculoskeletal disorders and various cancer types. Obesity develops from long-termed physiological imbalances in energy expenditure.. One of the therapeutic strategies in managing obesity is inhibition of pancreatic lipase, a key enzyme responsible for the digestion of fats and triglycerides. The aim of the present study was to synthesize silver nanoparticles (Ag-NP) from Ficus racemosa fruit extract and to analyze its activity on pancreatic lipase enzyme using spectroscopic, in vitro and in silico methods.
Materials and Methods: The phytoconstituent were separated in Ficus racemosa fruit extract by thin layer chromatography technique. The bioactive compound was also identified by gas chromatography-mass spectrometry analysis. Pancreatic lipase inhibition assay was performed in vitro and confirmed by molecular docking analysis.
Results: The F. racemosa fruit showed the highest pancreatic lipase inhibitory activity. Molecular docking studies also exhibited good binding affinity of compounds (Diethyl Phthalate) with pancreatic lipase enzymes.
Conclusion: Finally, it is concluded that further derivation of such compounds could serve as the new templates for obesity.
Comparison of serum nitric oxide levels with case severity in pre-eclampsia – A case control study
Authors: Sangappa Virupaxappa Kashinakunti , Devaranavadagi Basavaraj , Devaranavadagi Basavaraj , Rangappa Manjula , Ashalata Mallapur 
Published: April 2021

Introduction and Aim: In preeclampsia(PE) due to abnormal trophoblastic invasion of the maternal spiral arteries leads to decreased uteroplacental circulation. Nitric oxide (NO) is involved in regulation offeto-placental vascular permeability and resistance. It also affects maturation, development of the placenta and foetal survival. Maternal serum NO levels are controversial in PEandonly few studies have focused on birth outcomes. Hence, the current study was undertaken to estimate and compare the maternal serum NOlevels in normal pregnant and PE womenandalso see the correlation betweenmaternal serum NO level with severity of PEand to study its association with birth outcome.
Materials and Methods:The study was conductedat a tertiary care hospital in North Karnataka, India.Forty singleton primigravida PE patients diagnosed and classified as mild/severePE, as per ACOG guidelines and 40 healthy pregnant were selected for the study. NO was estimated by ELISA method.
Results: NO was high in PE cases than controls but it was not statistically significant. But NO was significantly (p=0.03) higher in mild PE than severe PE patients. The NO level negatively correlated significantly (p=0.031) with case severity. Maternal serum NO did not show any significant correlation with birth weight and APGAR score of the new born baby.
Conclusion:In mild PE rise in maternal serum NO, may be to due compensatory mechanism to normalise persistently elevated blood pressure and decreased level of serum NO in severe PE may be due to down-regulation of the nitric oxide synthase.
Seroprevalence of antibodies against varicella among medical students - a need for immunization record for medical school admission
Authors: Jhancy Malay , Bernhardt Grisilda Vidya , Risla Maryam , Khanam Munazza , Sultana Syeda Sana 
Published: April 2021

Introduction and Aim:This study was conducted at a medical University in UAE to assess the risk of acquiring Varicella – a vaccine-preventable disease, by estimating antibody titers among the clinically exposed students to provide a scientific implementation of immunization guideline during admission to medical school.
Materials and Methods: This cross-sectional study involved 88 students in clinical years attending a medical college in the UAE. The students' demographics, vaccination data, and history of natural infection with vaccine-preventable communicable infectious diseases were collected, with more significance on Varicella. Blood samples were collected to determine varicella IgG via ELISA.

Results:Out of 88 medical students, 20.45% of students had vaccination during childhood and 60.22%of students had a natural infection in the last five years. Three students (3.4%), who had childhood vaccination acquired the infection which is statistically significant during their clinical study years. 70.4% of students who had childhood vaccination and natural infection are at risk of acquiring varicella infections due to the waning of antibodies. 13.64% were found to be negative for varicella antibody titers are at the highest risk.

Conclusion:Medical students are most susceptible to acquiring the infection. Medical Universities should take up a policy, that each student needs to take booster vaccinations as a mandatory requirement before admission into the first year, which is practiced as an admission protocol in Western countries like the United States of America but not in Asian countries. Special emphasis should be placed on catch-up vaccination of students because the likelihood of severe infection increases with age.
Antibacterial activity of aquatic actinomycete,Actinoplanes digitatisDnj-2 (MN567713)
Authors: Bawazir Ali Mohammed , Jayashankar M. , Shantaram Manjula 
Published: April 2021

Introduction and Aim: There are centers for antibiotics in the nature to treat disease by looking for different sources, for example, actinomycetes, are approximately two-thirds of naturally occurring antibiotics, having much of medical importance, have been isolated from actinomycetes.The aim of the present study was to isolate and to identify the actinomycetes having antagonistic activity.

Materials and Methods: An actinomycetes strain isolated from dam soil sample collected from Alnajl dam of Hadhramout Yemen, showed antibacterial activity against selected microbial pathogens. The nutritional requirements and cultural conditions for maximal growth to produce secondary metabolites have been optimized under shake flask conditions. The growth and production of secondary metabolites were maximal with the use of SCA medium supplemented at pH 7.0, and incubation temperature and time of 37?and 20 days respectively.

Results:Based on morphological, biochemical, physiological and phylogenetic characterization, the strain was identified as Actinoplanes digitatisDnj-2 (MN567713). The ethyl acetate extract (1g/mL) obtained from the isolate showed significant antibacterial activity against Gram-negative bacteria- Escherichiacoli (21cm) and Pseudomonas aeruginosa (29cm) and Gram-positive bacteria- Bacillus subtitles(31cm) and Staphylococcus aureus (22cm) when compared with penicillin G 10 units.

Conclusion:In conclusion, the isolated strain has broad spectrum of antagonistic activity against Gram-positive and Gram-negativebacteria.
Efficacy of motor therapy over sensorimotor therapy in upper limb functions of post stroke patients
Authors: Rajalaxmi V. , Tharunya M. , Subramanian S.S. , Vaishnavi G. , Kumar K Chandra , Sukala N. , Balathandayutham K. 
Published: April 2021

Introduction and Aim:Strokeis one of the leading causes of death and disability in India. The incidence of stroke rapidly increases with age, doubling for each decade after 55.In the majority of patients the upper limb is severely impaired than lower limb. The aim of this study was to analyze the efficacy of motor therapy over sensorimotor therapy in upper limb functions of post stroke patients.

Materials and Methods: This was an experimental study, of pre-post type, that was conducted in the outpatient department of Physiotherapy at ACS Medical College and Hospital,chennai.30 samples were selected from 45 volunteers according to inclusion criteria and the study was conducted for Group A received sensorimotor therapy for one session/day for 6 days a week for 12 weeks. Group B received motor therapy for one session/day for 6 days a week for 12 weeks. Pre and post measurement were done using motor assessment scale, stroke upper limb capacity scale, action research arm test and nine-hole peg test.

Results: There was a significant difference in mean values of group A and B on comparison. Group A seems to be more effective than group B.

Conclusion: The study concludes that both motor therapy and sensorimotor therapy are beneficial in stroke rehabilitation, but sensorimotor therapy is more effective in improving the gross and fine motor skills of the upper limb of stroke patients.