bluuebunny/crossref_metadata_2025_split huggingface dataset:
Drug use disorder and risk of incident and fatal prostate cancer among Swedish men: a nationwide epidemiological study
Authors: Dahlman Disa , Li Xinjun , Crump Casey , Sundquist Jan , Sundquist Kristina 
Published: November 2021

Abstract
Purpose
Prostate cancer is the second most common cancer in men and a leading cause of cancer mortality worldwide. Men with drug use disorders (DUD) may potentially be at high risk for prostate cancer mortality because of delayed diagnosis and/or undertreatment. In this study, we aimed to investigate prostate cancer incidence, mortality, and stage at time of diagnosis among men with DUD compared to the general male population in Sweden.

Methods
We performed a follow-up study based on Swedish national register data for the period January 1997–December 2016. The study was based on 1,361,532 men aged 50–75 years at inclusion, of whom 9,259 were registered with DUD. Cox regression analysis was used to compute adjusted hazard ratios (HRs) for incident and fatal prostate cancer, and cancer stage at time of diagnosis, associated with DUD.

Results
DUD was associated with a slightly increased risk of incident prostate cancer (HR: 1.07, 95% confidence interval [CI] 1.00–1.14, p = 0.048) and substantially higher risk of fatal prostate cancer (HR: 1.59, 95% CI 1.40–1.82, p < 0.001), adjusted for age, socioeconomic factors, and comorbidities related to tobacco smoking and alcohol use disorder. No association was found between DUD and prostate cancer stage at diagnosis.

Conclusions
Men with DUD have an increased risk of fatal prostate cancer, possibly related to undertreatment in this patient population. Our findings should raise attention among medical staff and decision-makers towards a disadvantaged group of men in need of easily accessible prostate cancer evaluation and treatment.
Market power and journalistic quality
Authors: Leroch Martin 
Published: November 2021

AbstractThe political news media play an important role in the successful working of democratic societies. In order to fulfill this role, a sufficient level of journalistic quality is required. Most Western societies rely on the market as means to assure this level of quality. This implies regulation of the media sector by competition law, which may take different attitudes towards market power. While it is undisputed that some aspects of competition between political news media firms yield beneficial social outcomes, empirical findings regarding the impact of changes in market power are less straightforward. In the present analysis, I aim to understand whether an increase in market power may lead to an increase in journalistic quality. To this end,I formally model a demand function for media outlets based on the empirically justified assumption that preferences for journalistic quality systematically differ among consumers according to their education. I refer to this finding as consumption capital in a wide sense. Using a model of monopolistic competition, I find that, if consumption capital is sufficiently high, an increase in market power is associated with an increase in journalistic quality.
The perception problem: a comparison of teachers’ self-perceptions and students’ perceptions of instructional quality
Authors: Wisniewski Benedikt , Röhl Sebastian , Fauth Benjamin 
Published: November 2021

AbstractTeachers’ self-perceptions and their students’ perceptions of the three basic dimensions of instructional quality were compared based on a sample of 171 classes and their teachers in German secondary education. Low to moderate correlations (r= .35 to .50) were found between the two perspectives. Differences in perceptions vary across teachers based on favorable and less favorable students’ assessments. Results from latent profile analyses based on perception combinations of teachers and their classes hint at four differential profiles, reflecting to a large extent patterns of under- and overestimation of people’s own competence identified in previous research. Significant differences in gender among individuals assigned to the four profiles could be found. Implications of identifying the divergence between teachers’ and students’ perceptions of instructional quality for reflective practice are discussed.
Stochastic satellite tracking with constrained budget via structured-chromosome genetic algorithms
Authors: Gentile Lorenzo , Greco Cristian , Minisci Edmondo , Bartz-Beielstein Thomas , Vasile Massimiliano 
Published: November 2021

AbstractThis paper focuses on the scheduling under uncertainty of satellite tracking from a heterogeneous network of ground stations taking into account allocated resources. An optimisation-based approach is employed to efficiently select the optimal tracking schedule that minimises the final estimation uncertainty. Specifically, the scheduling is formulated as a variable-size problem, and a Structured-Chromosome Genetic Algorithm is developed to tackle the mixed-discrete global optimisation. The search algorithm employs genetic operators specifically revised to handle hierarchical search spaces. An orbit determination routine is run within each call to the fitness function to quantify the estimation uncertainty resulting from each candidate tracking schedule. The developed scheduler is tested on the tracking optimisation of a satellite in low Earth orbit, a highly perturbed dynamical regime. The obtained results show that the variable-size variants of Genetic Algorithms always outperform the fixed-size counterparts employed for comparison. In particular, Structured-Chromosome Genetic Algorithm is shown to find significantly better schedules under severely limited budgets.
Crowdlending: mapping the core literature and research frontiers
Authors: Ribeiro-Navarrete Samuel , Piñeiro-Chousa Juan , López-Cabarcos M. Ángeles , Palacios-Marqués Daniel 
Published: November 2021

AbstractPeer-to-peer (P2P) lending uses two-sided platforms to link borrowers with a crowd of lenders. Despite considerable diversity in crowdlending research, studies in this area typically focus on several common research topics, including information asymmetries, social capital, communication channels, and rating-based models. This young research field is still expanding. However, its importance has increased considerably since 2018. This rise in importance suggests that P2P lending may offer a promising new scientific research field. This paper presents a bibliometric study based on keyword co-occurrence, author and reference co-citations, and bibliographic coupling. The paper thus maps the key features of P2P lending research. Although many of the most cited papers are purely financial, some focus on behavioral finance. The trend in this field is toward innovative finance based on new technologies. The conclusions of this study provide valuable insight for researchers, managers, and policymakers to understand the current and future status of this field. The variables that affect new financial contexts and the strategies that promote technology-based financial environments must be investigated in the future.
Hypoglycemic Effect of Electroacupuncture at ST25 Through Neural Regulation of the Pancreatic Intrinsic Nervous System
Authors: Xu Tiancheng , Yu Zhi , Liu Yun , Lu Mengjiang , Gong Meirong , Li Qian , Xia Youbing , Xu Bin 
Published: November 2021

AbstractElectroacupuncture (EA) is considered to have potential antidiabetic effects; however, the role of the pancreatic intrinsic nervous system (PINS) in EA-induced amelioration of type 2 diabetes (T2DM) remains unclear. Therefore, we investigated whether EA at ST25 exerts any beneficial effects on insulin resistance (IR), inflammation severity, and pancreaticβcell function via the PINS in a rat model of a high-fat diet-streptozotocin (HFD/STZ)-induced diabetes. To this end, Sprague Dawley rats were fed with HFD to induce IR, followed by STZ (35 mg/kg, i.p.) injection to establish the T2DM model. After hyperglycemia was confirmed as fasting glucose level > 16.7 mmol/L, the rats were treated with EA (2 mA, 2/15 Hz) for the next 28 days. Model rats showed increased serum glucose, insulin, IR, and TNF-αlevels with a concomitant decrease inβcell function. Microscopy examination of the pancreas revealed pathological changes in islets, which reverted to near-normal levels after EA at ST25. EA improved islet cell morphology by increasing islet area and reducing vacuolation. EA at ST25 decreased transient receptor potential vanilloid 1 (TRPV1) and increased substance P (SP) and calcitonin gene-related peptide (CGRP) expression. Subsequently, insulin secretion decreased and impaired pancreatic endocrine function was restored through the TRPV1 channel (SP/CGRP)-insulin circuit. EA increased choline acetyltransferase and neuropeptide Y expression and controlled inflammation. It also enhanced the cocaine and amphetamine-regulated transcript prepropeptide expression and promoted glucagon-like peptide-1 secretion. Additionally, the electrophysiological activity of PINS during acupuncture (2.71 ± 1.72 Hz) was significantly increased compared to the pre-acupuncture frequency (0.32 ± 0.37 Hz,P< 0.05). Thus, our study demonstrated the beneficial effect of EA onβcell dysfunction via the PINS in rat models of HFD-STZ-induced T2DM.
Experimental study of standing and walking at work — What is compatible with physiological characteristics and human needs?
Authors: Rücker Lisa , Brombach Johannes , Bengler Klaus 
Published: November 2021

AbstractAn experimental study with two scenarios S1 and S2 was conducted, in which the standing and walking proportions as well as movement dynamics were varied. Eleven participants have taken part in the study for 2.5 h each (cycle time: 90 s). By means of surface electromyography, the static and dynamic components of muscle strain as well as the muscle fatigue were recorded and compared with the results of water plethysmography and a structured subjective rating survey. The results of the EMG study showed significantly higher dynamic components of the EA at S2 compared to S1, while the static components for the same activities did not show any significant difference, as expected. S1 and S2 always led to an increase in volume of the lower leg. Standing with less walking (S1) resulted in a significantly higher increase than standing with a higher proportion of walking and stronger dynamic movements (S2). In scenario S2, compared to scenario S1, the participants reported weaker subjective complaints which were also reported later in time. The results on muscular fatigue indicated only partially significant differences between S1 and S2. The results make clear that the dynamics of movement are a decisive criterion for assessing standing activities.Practical Relevance: To relieve strain during standing work, “real” walking movement must be integrated into the workflow. It could be shown that only a small step to the side or a few “shuffling” steps are not sufficient. In contrast, it is compatible with human physiological characteristics to make correct steps and dynamically activate the leg muscles.
Roboethics principles and policies in Europe and North America
Authors: Langman Sofya , Capicotto Nicole , Maddahi Yaser , Zareinia Kourosh 
Published: November 2021

AbstractRobotics and artificial intelligence (AI) are revolutionizing all spheres of human life. From industrial processes to graphic design, the implementation of automated intelligent systems is changing how industries work. The spread of robots and AI systems has triggered academic institutions to closely examine how these technologies may affect the humanity—this is how the fields of roboethics and AI ethics have been born. The identification of ethical issues for robotics and AI and creation of ethical frameworks were the first steps to creating a regulatory environment for these technologies. In this paper, we focus on regulatory efforts in Europe and North America to create enforceable regulation for AI and robotics. We describe and compare ethical principles, policies, and regulations that have been proposed by government organizations for the design and use of robots and AI. We also discuss proposed international regulation for robotics and AI. This paper tries to highlight the need for a comprehensive, enforceable, and agile policy to ethically regulate technology today and in the future. Through reviewing existing policies, we conclude that the European Unition currently leads the way in defining roboethics and AI ethical principles and implementing them into policy. Our findings suggest that governments in Europe and North America are aware of the ethical risks that robotics and AI pose, and are engaged in policymaking to create regulatory policies for these new technologies.
Impact of precoding on reimbursement in diagnosis-related group systems: Randomized controlled trial
Authors: Tarantino Ignazio , Widmann Bernhard , Warschkow Rene , Weitzendorfer Michael , Bock Susanne , Roeske Sandra , Abbassi Fariba , Sortino Rosita , Schmied Bruno M. , Steffen Thomas 
Published: November 2021

Abstract

Background
Complete and correct documentation of diagnosis and procedures is essential for adequate health provider reimbursement in diagnosis-related group (DRG) systems. The objective of this study was to investigate whether daily monitoring and semiautomated proposal optimization of DRG coding (precoding) is associated with higher reimbursement per hospitalization day.

Materials and methods
This parallel-group, unblinded, randomized clinical trial randomized patients 1:1 into intervention (precoding) and control groups. Between June 12 and December 6, 2019 all hospitalized patients (1566 cases) undergoing elective or emergency surgery at the department of surgery in a Swiss hospital were eligible for this study. By random sample selection, cases were assigned to the intervention (precoding) and control groups. The primary outcome was the total reimbursement, divided by the length of stay.

Results
Of the 1205 randomized cases, 1200 (precoding group: 602) remained for intention-to-treat, and 1131 (precoding group: 564) for per-protocol analysis. Precoding increased reimbursement per hospitalization day by 6.5% (160 US dollars; 95% confidence interval 31 to 289; P = 0.015). In a regression analysis patients hospitalized 7 days or longer, precoding increased reimbursement per day by 10.0% (246 US dollars; 95% confidence interval −12 to 504; P = 0.021). More secondary diagnoses (mean [SD]: 5.16 [5.60] vs 4.39 [5.34]; 0.77; 95% confidence interval 0.15 to 1.39; P = 0.015) and nonsurgical postoperative complications (mean [SD]: 0.68 [1.45] vs 0.45 [1.12]; 0.23; 95% confidence interval 0.08 to 0.38; P = 0.002) were documented by precoding. No associated was observed regarding the length of stay, total reimbursement, or case mix index. The mean (SD) precoding time effort was 37 (27) minutes per case.

Conclusion
Physician-led precoding increases DRG-based reimbursement. Precoding is time consuming and should be focused on cases with a longer hospital stay to increase efficiency.

Highlights
Coronavirus disease 2019 (COVID-19) screening system utilizing daily symptom attestation helps identify hospital employees who should be tested to protect patients and coworkers
Authors: Kim Ellen , Morris Charles A. , Klompas Michael , Zhang Haipeng , Landman Adam B. , Eappen Sunil , Hopcia Karen , Hashimoto Dean M. , Salmasian Hojjat 
Published: November 2021

AbstractObjective:To investigate the effectiveness of a daily attestation system used by employees of a multi-institutional academic medical center, which comprised of symptom-screening, self-referrals to the Occupational Health Services team, and/or a severe acute respiratory coronavirus virus 2 (SARS-CoV-2) test.Design:We conducted a retrospective cohort study of all employee attestations and SARS-CoV-2 tests performed between March and June 2020.Setting:A large multi-institutional academic medical center, including both inpatient and ambulatory settings.Participants:All employees who worked at the study site.Methods:Data were combined from the attestation system (COVIDPass), the employee database, and the electronic health records and were analyzed using descriptive statistics including χ2, Wilcoxon, and Kruskal-Wallis tests. We investigated whether an association existed between symptomatic attestations by the employees and the employee testing positive for SARS-CoV-2.Results:After data linkage and cleaning, there were 2,117,298 attestations submitted by 65,422 employees between March and June 2020. Most attestations were asymptomatic (99.9%). The most commonly reported symptoms were sore throat (n = 910), runny nose (n = 637), and cough (n = 570). Among the 2,026 employees who ever attested that they were symptomatic, 905 employees were tested within 14 days of a symptomatic attestation, and 114 (13%) of these tests were positive. The most common symptoms associated with a positive SARS-CoV-2 test were anosmia (23% vs 4%) and fever (46% vs 19%).Conclusions:Daily symptom attestations among healthcare workers identified a handful of employees with COVID-19. Although the number of positive tests was low, attestations may help keep unwell employees off campus to prevent transmissions.
Resilience: Directions for an Uncertain Future Following the COVID‐19 Pandemic
Authors: Galaitsi Stephanie , Kurth Margaret , Linkov Igor 
Published: November 2021

AbstractThe concept of resilience is multi‐faceted. This commentary builds upon the analytical distinctions of resilience provided by Urquiza et al. (2021, https://doi.org/10.1029/2020EF001508). In response to this article, we emphasize several distinctions between resilience and other systems concepts. These include distinctions between resilience, risk, and vulnerability, the tradeoff between resilience and efficiency, resilience contrasted with robustness, the relationship between resilience and sustainability, and finally methods for building resilience‐by‐design or resilience‐by‐intervention. Improving understanding of these concepts will enable planners to select resilience strategies that best support their system goals. We use examples from the 2020–2021 coronavirus pandemic to illustrate the concepts and the juxtapositions between them.
The Oceanic Barrier Layer in the Eastern Indian Ocean as a Predictor for Rainfall Over Indonesia and Australia
Authors: Ivanova Detelina P. , McClean Julie L. , Sprintall Janet , Chen Ru 
Published: November 2021

AbstractBarrier layers in the tropics trap heat in a shallow and stable near‐surface layer and limit entrainment of cooler water from below. Both processes act to increase sea surface temperature and enhance atmospheric convection. The high resolution fully coupled pre‐industrial Energy Exascale Earth System Model version 0 (E3SMv0) is used to investigate the relationship between barrier layers in the eastern Indian Ocean during the wet season with local atmospheric convection and remote rainfall. A partial least squares regression reveals a significant relationship between Australasian rainfall and the barrier layer thickness (BLT) west of Sumatra, occurring one month earlier. The largest positive regression coefficients are over northern Australia. The region west of Sumatra is strategically located where the East‐Asian monsoon moisture flows toward northern Australia. Thickening of the west Sumatra BLT intensifies evaporation and local convection and amplifies the moisture transported to Australia acting to increase the terrestrial rainfall.
Uncertainties in Kelvin Waves in ECMWF Analyses and Forecasts: Insights From Aeolus Observing System Experiments
Authors: Žagar N. , Rennie M. , Isaksen L. 
Published: November 2021

AbstractThe European Space Agency Earth Explorer mission Aeolus with the first spaceborne Doppler Wind Lidar onboard provides global coverage of wind profiles twice per day. This paper discusses the impact of assimilating Aeolus winds on the quality of tropical analyses and forecasts using the observing system experiments of the European Centre for Medium‐Range Weather (ECMWF). Presented examples show that Aeolus wind profiles bring changes to the Kelvin wave structure in the layers with a significant vertical shear during the easterly phase of the quasi‐biennial oscillation in the period May to September 2020. Comparing Kelvin waves in analyses and forecasts with and without Aeolus winds, it is argued that improved ECMWF forecasts in the tropical tropopause layer are due to vertically propagating Kelvin waves.
Earthquake Rupture and Tsunami Generation of the 2015 Mw 5.9 Bonin Event Revealed by In Situ Pressure Gauge Array Observations and Integrated Seismic and Tsunami Wave Simulation
Authors: Kubota Tatsuya , Saito Tatsuhiko , Fukao Yoshio , Sugioka Hiroko , Ito Aki , Tonegawa Takashi , Shiobara Hajime , Yamashita Mikiya 
Published: November 2021

AbstractOn September 1, 2015, an Mw 5.9 interplate earthquake occurred near the Bonin Trench. An array of in situ ocean‐bottom absolute pressure gauges (APGs) observed its tsunami generation field consisting of static and dynamic pressure changes due to tsunami and crustal deformation and due to seismic motion, respectively, under much higher station density than ever reported. We propose an approach to synthesize the pressure change inside the focal area, which reproduces the APG waveforms well. We further successfully estimate the finite fault model of the earthquake and constrain the rupture duration only from the APG data. The relatively low stress drop and seismic wave radiation from the fault model may suggest the nature of a tsunami earthquake. The in situ APGs have a large potential to reveal the broadband source process of the earthquake, which is essential to understand the seismotectonics in the subduction zone.
Quantifying the Lobe Reconnection Rate During Dominant IMF By Periods and Different Dipole Tilt Orientations
Authors: Reistad J. P. , Laundal K. M. , Østgaard N. , Ohma A. , Burrell A. G. , Hatch S. M. , Haaland S. , Thomas E. G. 
Published: November 2021

AbstractLobe reconnection is usually thought to play an important role in geospace dynamics only when the Interplanetary Magnetic Field (IMF) is mainly northward. This is because the most common and unambiguous signature of lobe reconnection is the strong sunward convection in the polar cap ionosphere observed during these conditions. During more typical conditions, when the IMF is mainly oriented in a dawn‐dusk direction, plasma flows initiated by dayside and lobe reconnection both map to high‐latitude ionospheric locations in close proximity to each other on the dayside. This makes the distinction of the source of the observed dayside polar cap convection ambiguous, as the flow magnitude and direction are similar from the two topologically different source regions. We here overcome this challenge by normalizing the ionospheric convection observed by the Super Dual Aurora Radar Network (SuperDARN) to the polar cap boundary, inferred from simultaneous observations from the Active Magnetosphere and Planetary Electrodynamics Response Experiment (AMPERE). This new method enable us to separate and quantify the relative contribution of both lobe reconnection and dayside/nightside (Dungey cycle) reconnection during periods of dominating IMF By. Our main findings are twofold. First, the lobe reconnection rate can typically account for 20% of the Dungey cycle flux transport during local summer when IMF By is dominating and IMF Bz ≥ 0. Second, the dayside convection relative to the open/closed boundary is vastly different in local summer versus local winter, as defined by the dipole tilt angle.