bluuebunny/crossref_metadata_2025_split huggingface dataset:
Readability and Suitability of Spanish-Language Hearing Aid User Guides
Authors: Gaeta Laura , Garcia Edward , Gonzalez Valeria 
Published: May 2021

Purpose
The purpose of this study was to evaluate the readability and suitability of Spanish-language hearing aid user guides.

Method
Hearing aid user guides in English and Spanish were downloaded for analysis. Readability for the English guides was calculated using the Flesch Reading Ease Scale and the Flesch–Kincaid Readability Formula, and readability for the Spanish guides was calculated using the Fernandez–Huerta and Spaulding Formula and Fry Graph. The Suitability Assessment of Materials was used to rate the suitability of each Spanish and English pair of hearing aid user guides.

Results
Of the nine manufacturers that had materials available in English, only five had guides available in Spanish. Although readability for the Spanish and English user guides was similar, both guides were written, on average, at the eighth grade level. Suitability for the analyzed Spanish and English user guides was 78% and 80%, respectively.

Conclusions
Spanish-language hearing aid user guides were lacking in readability and suitability. Given that patients with limited proficiency in English, including the Hispanic population, are at risk for low health literacy, providers and manufacturers are encouraged to create more Spanish-language materials. User guides in both languages would benefit from revisions to improve readability and suitability.

Supplemental Material

https://doi.org/10.23641/asha.14569497
Exploring Outcomes of an Asynchronous Learning Module on Increasing Cultural Competence for Speech-Language Pathology Graduate Students
Authors: Daughrity Belinda 
Published: May 2021

Purpose
Cultural competence is an essential tool for speech-language pathologists and other allied health care professionals in providing ethical and clinically competent care. Determining pedagogical approaches to teaching cultural competence skills to students training in preprofessional programs is imperative to effectively convey the importance of cultural awareness prior to students embarking on their professional careers.

Method
Forty-five (45) speech-language pathology graduate students were administered a multicultural knowledge quiz before and after a targeted, asynchronous learning module on cultural competence and again 2 months later.

Results
Quiz scores indicated significant findings immediately following a cultural competence learning module with an additional increase in scores at follow-up. Scores were not significant for minority background but were significant for clinical experience.

Conclusions
Evidence indicates a brief, targeted video module can positively impact cultural competence skills for speech-language pathology graduate students regardless of clinical experience. Results suggest a combination of targeted instruction along with repeated clinical experience produces the most significant improvement over time. As the current pilot study was employed to test methodology and results are not generalizable, implications for future pedagogical approaches and research studies with comprehensive methodological approaches are provided.

Supplemental Material

https://doi.org/10.23641/asha.14569482
Irritant-Induced Chronic Cough Triggers: A Scoping Review and Clinical Checklist
Authors: Sandage Mary J. , Ostwalt Elizabeth S. , Allison Lauren H. , Cutchin Grace M. , Morton Mariah E. , Odom Shelby C. 
Published: May 2021

PurposeThe primary aim of this review was to identify environmental irritants known to trigger chronic cough through the life span and develop a comprehensive clinically useful irritant checklist.MethodA scoping review was conducted using the Preferred Reporting Items for Systematic Review and Meta-Analysis Extension for Scoping Reviews, checklist, and explanation. English-language, full-text resources were identified through Medline, PsycINFO, SPORTDiscus, Web of Science, and ProQuest Dissertations and Theses Global.ResultsA total of 1,072 sources were retrieved; of these, 109 were duplicates. Titles of abstracts of 963 articles were screened, with 295 selected for full-text review. Using the exclusion and inclusion criteria listed, 236 articles were considered eligible and 214 different triggers were identified. Triggers were identified from North America, Europe, Africa, Asia, and Australia. Occupational exposures were also delineated.ConclusionsA clinically useful checklist of both frequently encountered triggers and idiosyncratic or rare triggers was developed. The clinical checklist provides a unique contribution to streamline and standardize clinical assessment of irritant-induced chronic cough. The international scope of this review extends the usefulness of the clinical checklist to clinicians on most continents.
Internal Consistency and Convergent Validity of Self-Report and By-Proxy Measures of Depression in Persons With Aphasia
Authors: Ashaie Sameer A. , Cherney Leora R. 
Published: May 2021

Purpose
Depression assessment is challenging in persons with aphasia given their language impairment. Studies have used both self-report scales and by-proxy measures of depression in persons with aphasia. However, the validity of these measures has been called into question. The aim of this study was to conduct a preliminary investigation into aspects of validity of the community version of the Stroke Aphasia Depression Questionnaire (SADQ-10) and the Center for Epidemiological Studies Depression Scale–Revised (CESD-R).

Method
Twenty-four participants with chronic aphasia completed the CESD-R, the Patient-Reported Outcomes Measurement Information System Global Mental Health scale (PROMIS GMH), and the Dynamic Visual Assessment of Mood Scales (D-VAMS) while their caregivers completed the SADQ-10. Internal consistency of the CESD-R and the SADQ-10 and the convergent validity of the CESD-R, SADQ-10, PROMIS GMH, and D-VAMS were examined.

Results
The SADQ-10 and the CESD-R were internally consistent. The CESD-R was moderately correlated with the SADQ-10, PROMIS GMH, and D-VAMS. However, the SADQ-10 was not correlated with the PROMIS GMH and D-VAMS.

Conclusions
We suggest both the CESD-R and the SADQ-10 be used together to screen for depression in persons with aphasia. Further studies with larger sample sizes need to be conducted to establish validity of other depression screening instruments in person with aphasia.
HNSF Log‐Demons: Diffeomorphic demons registration using hierarchical neighbourhood spectral features
Authors: Du Xiaogang , Gu Dongxin , Lei Tao , Wang Song , Zhang Xuejun , Meng Hongying 
Published: May 2021

AbstractMany biomedical applications require accurate non‐rigid image registration that can cope with complex deformations. However, popular diffeomorphic Demons registration algorithms suffer from difficulties for complex and serious distortions since they only use image greyscale and gradient information. To address these difficulties, a new diffeomorphic Demons registration algorithm is proposed using hierarchical neighbourhood spectral features namely HNSF Log‐Demons in this paper. In view of three important properties of hierarchical neighbourhood spectral features based on line graph such as rotation invariance, invariance of linear changes of brightness, and robustness to noise, the hierarchical neighbourhood spectral features of a reference image and a moving image is first extracted and these novel spectral features are incorporated into the energy function of the diffeomorphic registration framework to improve the capability of capturing complex distortions. Secondly, the Nystrm approximation based on random singular value decomposition is employed to effectively enhance the computational efficiency of HNSF Log‐Demons. Finally, the hybrid multi‐resolution strategy based on wavelet decomposition in the registration process is utilised to further improve the registration accuracy and efficiency. Experimental results show that the proposed HNSF Log‐Demons not only effectively ensures the generation of smooth and reversible deformation field, but also achieves better performance than state‐of‐the‐art algorithms.
Synthesis of Nilotinin M3: An Ellagitannin Containing an Isodehydrodigalloyl Group
Authors: Abe Hitoshi , Imai Haruka , Kanzaka Yuta , Sunatsuki Yukinari 
Published: May 2021

AbstractTotal synthesis of nilotinin M3, which is a member of the ellagitannin family of natural products containing an isodehydrodigalloyl (isoDHDG) group, was achieved using the Ullmann reaction to construct a highly functionalized diaryl ether.
Stereoselective Synthesis of Polyfunctionalized Nitrones through Conjugate Addition of α-Halo Hydrazones to Nitroso Compounds
Authors: Zhao Hong-Wu , Bi Xiao-Fan , Pang Hai-Liang , Tang Zhe , Zhang Heng , Cai Lu-Yu , Wu Hui-Hui , Fan Xiao-Zu 
Published: May 2021

AbstractIn the presence of Na2CO3, conjugate addition of α-halo hydrazones to nitroso compounds proceeded readily to give polyfunctionalized nitrones in reasonable chemical yields and excellent stereoselectivities. The chemical structure and the stereochemical configuration of the products were unambiguously identified by an X-ray single-crystal structural analysis.
The Mystery behind Relaxation Therapy: Adieu to Premenstrual Syndrome
Authors: Jose Ancy , Nayak Sabitha , Kamath Neetha , M. Nalini 
Published: May 2021

AbstractPremenstrual syndrome (PMS) is a very common condition leading to physical, emotional, and psychological distress in females during their reproductive years. Researchers found that as many three of every four menstruating women have experienced some form of PMS. Although the severity of this problem is great, a lot of confusion exists in both medical and lay communities about what is and is not effective for the treatment of PMS. It has a wide variety of signs and symptoms and it may tend to recur in a predictable pattern. The physical and emotional changes experienced with PMS may vary from just slightly noticeable to very intense. Lifestyle adjustments in every kind can help to reduce or manage the signs and symptoms of PMS. Apart from all these, one of the most beneficial methods to reduce the difficulties of PMS is relaxation therapy which includes meditation, visualization, autogenic, Tai Chi, hydrotherapy, exercise, massage, aromatherapy, biofeedback, relaxation breathing, progressive muscle relaxation (Jacobson’s progressive relaxation therapy and The Mitchells progressive relaxation therapy) and yoga. Thus when remedies are available why not we celebrate the inborn power of relieving PMS in women.
Mechanisms of Soft Tissue Injury
Authors: Arosarena Oneida A. , Eid Issam N. 
Published: May 2021

AbstractSoft tissue trauma to the face is challenging to manage due to functional and aesthetic concerns. Management requires careful regional considerations to maintain function such as visual fields and oral competence in periorbital and perioral injuries, respectively. Basic wound management principles apply to facial soft tissue injuries including copious irrigation and tension-free closure. There is no consensus and high-level evidence for antibiotic prophylaxis especially in various bite injuries. Ballistic injuries and other mechanisms are briefly reviewed. Scar revision for soft tissue injuries can require multiple procedures and interventions. Surgery as well as office procedures such as resurfacing with lasers can be employed and will be reviewed.
Massive Transfusion Protocols in Obstetric Hemorrhage: Theory versus Reality
Authors: Salmanian Bahram , Clark Steven L. , Hui Shiu-Ki R. , Detlefs Sarah , Aalipour Soroush , Meshinchi Asl Nazlisadat , Shamshirsaz Alireza A. 
Published: May 2021

Objective Massive transfusion protocols are widely implemented in obstetrical practice in case of severe hemorrhage; however, different recommendations exist regarding the appropriate ratios of blood product components to be transfused. We report our extensive experience with massive component transfusion in a referral center in which the standard massive transfusion protocol is modified by ongoing clinical and laboratory evaluation.
Study Design A retrospective chart review of all patients who had massive transfusion protocol activation in a level 4 referral center for obstetrical practice was performed from January 2014 to January 2020. Data collected included the etiology of obstetrical hemorrhage, number of blood products of each type transfused, crystalloid infusion, and several indices of maternal morbidity and mortality. Data are presented with descriptive statistics.
Results A total of 62 patients had massive transfusion protocol activation, of which 97% received blood products. Uterine atony was found to be the most common etiology for massive hemorrhage (34%), followed by placenta accreta spectrum (32%). The mean estimated blood loss was 1,945 mL. A mean of 6.5 units of packed red blood cells, 14.8 units of fresh frozen plasma and cryoprecipitate, and 8.3 units of platelets were transfused per patient. No maternal deaths were seen.
Conclusion The ratios of transfused packed red blood cell to fresh frozen plasma/cryoprecipitate and of packed red blood cell to platelet units varied significantly from the fixed initial infusion ratio called for by our massive transfusion protocol resulting in universally favorable maternal outcomes. When rapid laboratory evaluation of hematologic and clotting parameters is available, careful use of this information may facilitate safe modification of an initial fixed transfusion ratio based on etiology of the hemorrhage and individual patient response.
Key Points
Board Certification and Surgeon's Fee for Aesthetic Rhinoplasty
Authors: Blasberg Elizabeth A. , Golden Jacquelyn , Rubin Samuel , Spiegel Jeffrey H. 
Published: May 2021

AbstractElective rhinoplasty surgeons' fees vary considerably and are influenced by geographic surgeon density, surgeon's experience, local economic factors, patient demand, and other factors. The American Board of Facial Plastic and Reconstructive Surgery, the American Society of Plastic Surgery, and other organizations certify physicians who profess expertise in rhinoplasty. We sought to determine if specific board certification or experience correlates with higher rhinoplasty fee. An internet search was conducted of seven U.S. metropolitan areas using the search terms “rhinoplasty and “city name.” Top search results were surveyed for rhinoplasty fee, years of experience, annual volume of rhinoplasties, board certification, and other demographic data. Using both univariate and multivariate comparisons, the data were analyzed for forces having significant correlation with rhinoplasty fee. Sixty-seven surgeons were included in the study. The average price for ABFPRS certified surgeons was significantly higher than surgeons with other board certifications ($10,550.00 ± 3,722.10 compared with $8,524.50 ± 2816.30, p = 0.0142). The volume of rhinoplasties performed per year was also significantly correlated with fee charged for rhinoplasty by the surgeon (r = 0.37773, p = 0.032). Additionally, surgeons practicing on the West Coast (LA) charged significantly higher fees ($12,059.09 ± 3014.53) compared with the Mid United States. ($8316.07 ± 2449.43) and the East Coast ($9152.86 ± 3639.78) (p = 0.0047). On multivariable linear regression, controlling for volume of rhinoplasty and region of the United States, ABFPRS certified surgeons charged significantly higher fees for rhinoplasty (p = 0.0230). ABFPRS board certification correlates with higher fees charged for rhinoplasty. Other important variables include surgeon's annual rhinoplasty and practice on the West Coast.
Acute Essex-Lopresti Syndrome: About a Case of Brachioradialis Tendon Transfer
Authors: Charlotte Gabriel , Honecker Sophie , Xavier Fred , Facca Sybille , Lazarus Priscille , Liverneaux Philippe 
Published: May 2021

Abstract
Background The classic treatment for acute Essex-Lopresti syndrome is closed reduction percutaneous pinning (CRPP) of the distal radioulnar joint (DRUJ). This work aimed to verify whether it was possible to add a transfer of the brachioradialis tendon to the pinning.
Case Description The patient was a 39-year-old right-handed man, climbing instructor, who sustained the Mason II fracture and disjunction of the DRUJ. A transfer of the brachioradialis tendon severed from its muscle attach that was made through a bone tunnel passing through the radius and the neck of the ulna. The clinical and radiological result at the 6-month follow-up was satisfactory.
Literature Review and Clinical Relevance Our results in a single case showed that the brachioradialis tendon transfer was useful in acute Essex-Lopresti syndrome.
Valproic Acid Administration in Management of Status Epilepticus Causing Reye’s Syndrome
Authors: Kamath Pooja Prabhakar 
Published: May 2021

AbstractIntroduction Valproic acid is commonly used to treat seizures in children. Regular use of valproic acid is known to cause hepatic dysfunction, and in extremely rare cases, it is known to have caused Reye’s syndrome. There are very few reports of Reye’s syndrome caused by valproic acid use.Methods A 2-year asymptomatic girl underwent modified Blalock–Taussig shunt surgery for correction of tetralogy of Fallot. Postoperatively the girl developed status epilepticus, which did not subside with initial use of intravenous midazolam and phenytoin sodium. She eventually responded to two doses of intravenous valproic acid administered 10 minutes apart. She developed depressed sensorium and was put on mechanical ventilation. The following day’s laboratory investigations revealed raised levels of serum ammonia, serum glutamic-oxaloacetic transaminase (SGOT), and serum glutamic-pyruvic transaminase (SGPT) with normal serum bilirubin. Thus, a diagnosis of Reye’s syndrome was established. The patient succumbed to disease 2 days later.Discussion Reye’s syndrome is a rare and a fulminant illness seen typically in children following a viral illness and/or use of salicylates or other medications. There are rare reports of Reye’s syndrome following use of medications like valproic acid. This patient had a noninflammatory encephalopathy with hepatic dysfunction following two doses of valproic acid.Conclusion There are very few reports on Reye’s syndrome in the literature as it is a rare condition and diagnosis is difficult. Knowledge of the presentation of Reye’s syndrome is essential for treatment and management. When using drugs like valproic acid in children, liver enzymes and serum ammonia levels should be monitored.
Iatrogenic Bile Duct Injuries: An Overview and A Review of Literature
Authors: M. Vinoth , Joshi Abhijit 
Published: May 2021

Abstract​ Laparoscopic cholecystectomy (LC) is one of the most frequently performed surgical procedures worldwide. Iatrogenic bile duct injury (IBDI) is a serious complication of LC and has an incidence of 0.3 to 0.7%. Since it is associated with a significant and potentially lifelong morbidity as well as mortality, diagnosing IBDI as early as possible is of paramount importance. Management of bile duct injuries and prognosis of their surgical repair depend on the timing of its recognition, type and the extent of the injury. In this paper, we present a case of IBDI and attempt to discuss all its dimensions.
Microstructure and mechanical properties of atomic layer deposited alumina doped zirconia
Authors: Piirsoo Helle-Mai , Jõgiaas Taivo , Mändar Hugo , Ritslaid Peeter , Kukli Kaupo , Tamm Aile 
Published: May 2021

Atomic layer deposited alumina doped zirconia films can exhibit advanced mechanical properties with potential to increase the suitability of ZrO2 films for mechanically resilient coatings. In the present study, Al2O3-doped ZrO2 films were deposited on a TiN substrate to thicknesses around 100 nm at 300 °C. A zirconia film containing 4.6 mol. % Al2O3 was crystallized in its tetragonal polymorph. Increasing the Al2O3 content up to 5.8 and 8.2 mol. % stabilized the cubic polymorph in the ZrO2-based films. The films with even higher Al2O3 contents remained amorphous. All the crystalline films possessed a preferential grain orientation to extents differing beneath the surface and in the vicinity of the substrate. The most rigid films with hardness up to 15 GPa and elastic modulus above 170 GPa could be obtained when crystallized in the form of cubic ZrO2 stabilized upon doping with Al2O3. For all the crystalline films, the hardness and elastic modulus increased near the substrate.
A vertebrate adaptive radiation is assembled from an ancient and disjunct spatiotemporal landscape
Authors: Richards Emilie J. , McGirr Joseph A. , Wang Jeremy R. , St. John Michelle E. , Poelstra Jelmer W. , Solano Maria J. , O’Connell Delaney C. , Turner Bruce J. , Martin Christopher H. 
Published: May 2021

Significance
Most biodiversity evolved in rapid bursts of new species, adaptations, and ecological niches. However, this process of adaptive radiation is poorly understood. We used large-scale genomic sequencing across the entire Caribbean range of pupfishes to understand why radiation in this group is restricted to a single Bahamian island. We found that twofold higher gene flow to this island brought in new combinations of ancient adaptive mutations needed for colonizing novel ecological niches of scale-eating and snail-eating. Adaptation occurred in stages: first selection on feeding behavior, then selection for trophic morphology, and finally refinement through gene coding change. We demonstrate that young, localized radiations can emerge from a vast pool of adaptive genetic variation spread across time and space.
AP-3–dependent targeting of flippase ATP8A1 to lamellar bodies suppresses activation of YAP in alveolar epithelial type 2 cells
Authors: Kook Seunghyi , Wang Ping , Meng Shufang , Jetter Christopher S. , Sucre Jennifer M. S. , Benjamin John T. , Gokey Jason J. , Hanby Hayley A. , Jaume Alexa , Goetzl Laura , Marks Michael S. , Guttentag Susan H. 
Published: May 2021

SignificanceWe identify AP-3–mediated targeting of flippase ATP8A1 to lamellar bodies, lysosome-related organelles that store pulmonary surfactant for secretion from alveolar epithelial cells. Genetic AP-3 loss in cultured alveolar epithelial cells and in thepearlmouse model causes ATP8A1 retention in early sorting and/or recycling endosomes and concomitant accumulation of phosphatidylserine on endosomal membranes. This in turn elicits a toxic gain-of-function through Yes-activating protein and initiates lung injury programs that may contribute to progressive lung fibrosis associated with Hermansky Pudlak syndrome type 2.
A new design for an ultra-wideband microwave metamaterial absorber
Authors: Yu Yongjun , Sun Pingyuan , Wang Yunfan , Chen Zhaoyang 
Published: May 2021

Abstract
In this paper we propose a new design for an ultra-wideband microwave metamaterial absorber. This metamaterial absorber has a sandwich structure, and the top metal pattern is periodically arranged on the copper background. This metamaterial absorber is combined with Fe–Co composites and metamaterials, which solves the narrow-band problem of microwave absorption. We realize an absorptivity of more than 90% in the 2.16–18 GHz frequency band for normal incidence. The thickness of the structure is 0.61 mm (about 1/48.8 wavelength at the central frequency). The performance of the proposed absorber is not sensitive to the polarization of incident waves.