bluuebunny/crossref_metadata_2025_split huggingface dataset:
The achievement gap in reading competence: the effect of measurement non-invariance across school types
Authors: Rohm Theresa , Carstensen Claus H. , Fischer Luise , Gnambs Timo 
Published: October 2021

Abstract
Background
After elementary school, students in Germany are separated into different school tracks (i.e., school types) with the aim of creating homogeneous student groups in secondary school. Consequently, the development of students’ reading achievement diverges across school types. Findings on this achievement gap have been criticized as depending on the quality of the administered measure. Therefore, the present study examined to what degree differential item functioning affects estimates of the achievement gap in reading competence.

Methods
Using data from the German National Educational Panel Study, reading competence was investigated across three timepoints during secondary school: in grades 5, 7, and 9 (N = 7276). First, using the invariance alignment method, measurement invariance across school types was tested. Then, multilevel structural equation models were used to examine whether a lack of measurement invariance between school types affected the results regarding reading development.

Results
Our analyses revealed some measurement non-invariant items that did not alter the patterns of competence development found among school types in the longitudinal modeling approach. However, misleading conclusions about the development of reading competence in different school types emerged when the hierarchical data structure (i.e., students being nested in schools) was not taken into account.

Conclusions
We assessed the relevance of measurement invariance and accounting for clustering in the context of longitudinal competence measurement. Even though differential item functioning between school types was found for each measurement occasion, taking these differences in item estimates into account did not alter the parallel pattern of reading competence development across German secondary school types. However, ignoring the clustered data structure of students being nested within schools led to an overestimation of the statistical significance of school type effects.
Fast determination of phthalates in mussel samples by micro-matrix solid-phase dispersion (micro-MSPD) coupled with GC–MS/MS
Authors: Carro Nieves , Mouteira Ana , García Isabel , Ignacio María , Cobas Julio 
Published: October 2021

AbstractA fast, effective and low cost sample preparation method based on miniaturized matrix solid-phase dispersion (micro-MSPD) combined with gas chromatography coupled to tandem triple-quadrupole-mass spectrometry (GC–MS/MS) has been developed for the determination of six phthalate diesters (DMP, DEP, DBP, BzBP, DEHP and DnOP) in mussel samples. The six target compounds have been included in the list of priority pollutants by United States Environmental Protection Agency. The extraction step was optimized on real spiked mussel coming from Galician Rías by means of a factorial design. The final procedure involved the use of 0.45 g of sample, 0.5 g of dispersant agent (Florisil) and 3 mL of organic solvent (ethyl acetate). The optimized method was validated giving satisfactory analytical performance, low detection limits (0.09 to 6.73 ng g−1 dw) and high recoveries (93 and 114%). The validated method was applied to four real mussel samples coming from Galician Rías.
How stable is program quality in child care centre classrooms?
Authors: Varmuza Petr , Perlman Michal , Falenchuk Olesya 
Published: October 2021

AbstractIn the Early Childhood Education and Care (ECEC) sector there is a move to reduce oversight costs by reducing the frequency of quality assessments in providers who score highly consistently across time. However, virtually nothing is known about the stability of ECEC quality assessments over time. Using a validated measure of overall classroom quality, we examined stability of quality in a sample of over 1000 classrooms in licensed child care centres in Toronto, Canada over a 3-year period. Multilevel mixed-effects linear regression analyses revealed substantial instability across all types of ECEC centres, although publicly operated centres were somewhat more stable and tended to have higher quality scores. We also found substantial variance between classrooms within ECEC centres. None of the structural, child/family and neighbourhood characteristics we examined were significantly related to stability of quality ratings. The lack of stability found in our sample does not support the use of a risk-based approach to quality oversight in ECEC. Large within centre classroom quality variance suggest that all classrooms within a centre should be assessed individually. Furthermore, classroom level scores should be posted when scores are made public as part of accountability systems. Future research should, in addition to administrative data used in our study, explore how factors such as educator training, participation in program planning, reflective practices and ongoing learning might improve stability of quality over time.
The treasure inside barley seeds: microbial diversity and plant beneficial bacteria
Authors: Bziuk Nina , Maccario Lorrie , Straube Benjamin , Wehner Gwendolin , Sørensen Søren J. , Schikora Adam , Smalla Kornelia 
Published: October 2021

Abstract
Background
Bacteria associated with plants can enhance the plants’ growth and resistance against phytopathogens. Today, growers aim to reduce the use of mineral fertilizers and pesticides. Since phytopathogens cause severe yield losses in crop production systems, biological alternatives gain more attention. Plant and also seed endophytes have the potential to influence the plant, especially seed-borne bacteria may express their beneficiary impact at initial plant developmental stages. In the current study, we assessed the endophytic seed microbiome of seven genetically diverse barley accessions by 16S rRNA gene amplicon sequencing and verified the in vitro plant beneficial potential of isolated seed endophytes. Furthermore, we investigated the impact of the barley genotype and its seed microbiome on the rhizosphere microbiome at an early growth stage by 16S rRNA gene amplicon sequencing.

Results
The plant genotype displayed a significant impact on the microbiota in both barley seed and rhizosphere. Consequently, the microbial alpha- and beta-diversity of the endophytic seed microbiome was highly influenced by the genotype. Interestingly, no correlation was observed between the endophytic seed microbiome and the single nucleotide polymorphisms of the seven genotypes. Unclassified members of Enterobacteriaceae were by far most dominant. Other abundant genera in the seed microbiome belonged to Curtobacterium, Paenibacillus, Pantoea, Sanguibacter and Saccharibacillus. Endophytes isolated from barley seeds were affiliated to dominant genera of the core seed microbiome, based on their 16S rRNA gene sequence. Most of these endophytic isolates produced in vitro plant beneficial secondary metabolites known to induce plant resistance.

Conclusion
Although barley accessions representing high genetic diversity displayed a genotype-dependent endophytic seed microbiome, a core seed microbiome with high relative abundances was identified. Endophytic isolates were affiliated to members of the core seed microbiome and many of them showed plant beneficial properties. We propose therefore that new breeding strategies should consider genotypes with high abundance of beneficial microbes.
Defining gut mycobiota for wild animals: a need for caution in assigning authentic resident fungal taxa
Authors: Lavrinienko Anton , Scholier Tiffany , Bates Scott T. , Miller Andrew N. , Watts Phillip C. 
Published: October 2021

AbstractAnimal gut mycobiota, the community of fungi that reside within the gastrointestinal tract, make an important contribution to host health. Accordingly, there is an emerging interest to quantify the gut mycobiota of wild animals. However, many studies of wild animal gut mycobiota do not distinguish between the fungi that likely can reside within animal gastrointestinal tracts from the fungal taxa that are non-residents, such as macrofungi, lichens or plant symbionts/pathogens that can be ingested as part of the host’s diet. Confounding the non-resident and resident gut fungi may obscure attempts to identify processes associated with the authentic, resident gut mycobiota per se. To redress this problem, we propose some strategies to filter the taxa identified within an apparent gut mycobiota based on an assessment of host ecology and fungal traits. Consideration of the different sources and roles of fungi present within the gastrointestinal tract should facilitate a more precise understanding of the causes and consequences of variation in wild animal gut mycobiota composition.
The role of the gut microbiota in the dietary niche expansion of fishing bats
Authors: Aizpurua Ostaizka , Nyholm Lasse , Morris Evie , Chaverri Gloriana , Herrera Montalvo L. Gerardo , Flores-Martinez José Juan , Lin Aiqing , Razgour Orly , Gilbert M. Thomas P. , Alberdi Antton 
Published: October 2021

AbstractBackgroundDue to its central role in animal nutrition, the gut microbiota is likely a relevant factor shaping dietary niche shifts. We analysed both the impact and contribution of the gut microbiota to the dietary niche expansion of the only four bat species that have incorporated fish into their primarily arthropodophage diet.ResultsWe first compared the taxonomic and functional features of the gut microbiota of the four piscivorous bats to that of 11 strictly arthropodophagous species using 16S rRNA targeted amplicon sequencing. Second, we increased the resolution of our analyses for one of the piscivorous bat species, namelyMyotis capaccinii,and analysed multiple populations combining targeted approaches with shotgun sequencing. To better understand the origin of gut microorganisms, we also analysed the gut microbiota of their fish prey (Gambusia holbrooki). Our analyses showed that piscivorous bats carry a characteristic gut microbiota that differs from that of their strict arthropodophagous counterparts, in which the most relevant bacteria have been directly acquired from their fish prey. This characteristic microbiota exhibits enrichment of genes involved in vitamin biosynthesis, as well as complex carbohydrate and lipid metabolism, likely providing their hosts with an enhanced capacity to metabolise the glycosphingolipids and long-chain fatty acids that are particularly abundant in fish.ConclusionsOur results depict the gut microbiota as a relevant element in facilitating the dietary transition from arthropodophagy to piscivory.
Impurity profiling method development and validation of metformin hydrochloride and teneligliptin hydrobromide hydrate in their combination tablet dosage form by using RP-HPLC with UV/PDA detector
Authors: Musmade B. D. , Baraskar M. L. , Ghodke V. N. , Bhope S. G. , Padmanabhan S. , Lohar K. S. 
Published: October 2021

Abstract
Background
An accurate, precise and robust analytical method was developed for the impurity profiling in the metformin hydrochloride and teneligliptin hydrobromide hydrate tablet. The gradient was optimized for better separation of impurities by using BDS Hypersil C18 250 × 4.6 mm, 5µ column operated at 35 °C. The octane sulfonic acid and phosphate buffer with triethylamine at pH 3.0 were used as mobile phase A, and acetonitrile was used as mobile phase B. The mobile phase was pumped at 1.0 mL/min. The gradient was optimized for better resolution, and the chromatogram was monitored at 210 nm.

Results
The % recovery of teneligliptin and metformin HCL observed was above 90% from LOQ level to 150%. The correlation coefficient r2 was 0.999 for metformin HCl, teneligliptin, melamine, cyanocobalamin, teneligliptin impurity A and 0.998 for teneligliptin impurity B. The method was found unaffected by change in method variance during the robustness study. During the stress study with acid, base, peroxide and temperature, maximum degradation was observed with peroxide indicating the sensitivity of the molecule toward oxidative stress.

Conclusions
The developed method is precise, accurate, robust and linear and hence can be routinely used for the related substance analysis of metformin hydrochloride and teneligliptin hydrobromide hydrate tablet in the quality control laboratory at manufacturing site during the commercial manufacturing.
Response-Adapted Postinduction Strategy in Patients With Advanced-Stage Follicular Lymphoma: The FOLL12 Study
Authors: Luminari Stefano , Manni Martina , Galimberti Sara , Versari Annibale , Tucci Alessandra , Boccomini Carola , Farina Lucia , Olivieri Jacopo , Marcheselli Luigi , Guerra Luca , Ferrero Simone , Arcaini Luca , Cavallo Federica , Kovalchuk Sofya , Skrypets Tetiana , del Giudice Ilaria , Chauvie Stephane , Patti Caterina , Stelitano Caterina , Ricci Francesca , Pinto Antonello , Margiotta Casaluci Gloria , Zilioli Vittorio R. , Merli Anna , Ladetto Marco , Bolis Silvia , Pavone Vincenzo , Chiarenza Annalisa , Arcari Annalisa , Anastasia Antonella , Dondi Alessandra , Mannina Donato , Federico Massimo ,   on behalf of Fondazione Italiana Linfomi
Published: October 2021

PURPOSE We compared 2 years of rituximab maintenance (RM) with a response-adapted postinduction approach in patients with follicular lymphoma who responded to induction immunochemotherapy. METHODS We randomly assigned treatment-naïve, advanced-stage, high-tumor burden follicular lymphoma patients to receive standard RM or a response-adapted postinduction approach on the basis of metabolic response and molecular assessment of minimal residual disease (MRD). The experimental arm used three types of postinduction therapies: for complete metabolic response (CMR) and MRD-negative patients, observation; for CMR and MRD-positive (end of induction or follow-up) patients, four doses of rituximab (one per week, maximum three courses) until MRD-negative; and for non-CMR patients, one dose of ibritumomab tiuxetan followed by standard RM. The study was designed as noninferiority trial with progression-free survival (PFS) as the primary end point. RESULTS Overall, 807 patients were randomly assigned. After a median follow-up of 53 months (range, 1-92 months), patients in the standard arm had a significantly better PFS than those in the experimental arm (3-year PFS 86% v 72%; P < .001). The better PFS of the standard versus experimental arm was confirmed in all the study subgroups except non-CMR patients (n = 65; P = .274). The 3-year overall survival was 98% (95% CI, 96 to 99) and 97% (95% CI, 95 to 99) in the reference and experimental arms, respectively ( P = .238). CONCLUSION A metabolic and molecular response-adapted therapy as assessed in the FOLL12 study was associated with significantly inferior PFS compared with 2-year RM. The better efficacy of standard RM was confirmed in the subgroup analysis and particularly for patients achieving both CMR and MRD-negative.
Opportunity Costs of Surgical Resection and Perioperative Chemotherapy for Locoregional Pancreatic Adenocarcinoma
Authors: Lim Szu-Aun , Hao Scarlett B. , Boyd Breana A. , Mitsakos Anastasios , Irish William , Burke Aidan M. , Parikh Alexander A. , Snyder Rebecca A. 
Published: October 2021

PURPOSE: Given the perioperative morbidity and intensity of multimodality treatment, patients with resected pancreatic ductal adenocarcinoma (PDAC) spend a substantial amount of time in clinical care. The primary aim was to determine total time spent in multimodality care for patients with locoregional PDAC. METHODS: A cohort study of all patients who underwent curative-intent resection for PDAC at a single-institution, tertiary care center was performed (2015-2019). Exact times for all relevant visits were abstracted from the primary medical record, and travel time was calculated. Care time was divided into preoperative, surgical, radiation, and systemic therapy phases of care. Primary outcome measures were the percentage of total survival time (TST) and percentage of overall survival (OS) days spent in receipt of care. RESULTS: One hundred seven patients were included. Patients spent a median of 5.0% (interquartile range [IQR] 2.4%-10.1%) of TST and 11.0% (IQR, 5.7%-20.4%) of OS days in receipt of clinical care. Preoperative, surgical, radiation, and systemic therapy phases of care comprised a median of 0.9% (IQR, 0.4%-2.2%), 3.0% (IQR, 1.9%-6.8%), 4.4% (IQR, 3.6%-6.3%), and 10.0% (IQR, 6.2%-14.1%) of OS days. The median per-visit travel time was 60 minutes (IQR, 32-120), and the median cumulative travel time was 22.0 hours (IQR, 12.0-51.5). 12.1% (n = 13) and 7.8% (n = 4) of patients spent > 10% of TST in receipt of surgical and systemic therapy care, respectively. CONCLUSION: Patients with locoregional pancreatic cancer spend a considerable percentage of their survival time in receipt of oncologic care. Further research to determine predictors of increased time burden is warranted to better inform shared decision making.
Cento
Authors: Bernstein Charles ,   Various Voices
Published: October 2021

Abstract
A roundup of Charles Bernstein's interviews outside the US: (1) “Interview with Romina Freschi” (Argentina, 2005), previously published only in Spanish; (2) “Frequently Unasked Questions,” with Versatorium (Austria, 2011), previously published only in German in Der Standard; (3) “Interview with Philip Davenport” (England, 2012), focusing on the marginalization of radical formal poetry in the US versus the UK; (4) “Interview with Maurizio Medo” (Peru, 2014), previously published only in Spanish, focusing on the importance of Cage and Mac Low and the problems with the designations “experimental,” “representative,” and “failed”; (5) “Interview with Alcir Pécora and Régis Bonvicino” (Brazil, 2014), on the “infranatural” and echopoetics; (6) “Indigo: Interview with Paata Shamugia” (Georgia, 2016); (7) “Project Transcreation Interview with Runa Bandyopadhyay” (India, 2019); (8) “Interview by Habib Tengour in Pour ainsi dire,” a collection of Bernstein poems translated by Tengour (Algeria, 2019), previously published only in French; (9) “Interview with Mariano Peyrou” (Spain, 2020), previously published only in Spanish in El Mundo.
In the Un-American Tree: The L=A=N=G=U=A=G=E Poetries and Their Aftermath, with a Special Reference to Charles Bernstein, Translated
Authors: Lehto Leevi 
Published: October 2021

Abstract
Leevi Lehto, in a keynote on American poetry presented in China, outlines the challenges and possibilities of Language poetry outside the American context, with specific relation to the meaning of translation.
Breaking with the Family Form: Historical Categories, Social Reproduction, and Everyday Life in Late 1950s Rural China
Authors: Day Alexander F. 
Published: October 2021

AbstractThis article explores the way PRC historians use analytical categories by looking at the emergence of a divide between production and the social reproduction of labor (all the work that goes into producing and raising laborers) that transformed and structured rural everyday life during the Mao period. Everyday life is historical, produced in different ways under different material conditions, structured and shaped by social forms in motion. Thus, it is not an analytical frame through which historians can view the real content of the Mao period underneath the thin veneer of Maoist high politics and its categories. This article therefore argues that everyday life, far from a sphere resisting the impositions and dictates of the state, is fully implicated in the political-economic structuring of society. This is a call to not simply replace an earlier social science focus on the political economy of the PRC with a bottom-up or empirical view of everyday life, recognizing that everyday life is already a structured terrain. Rather than bringing in social science analytical categories from the outside or searching for an empirical real view from below, we need to investigate the emergence of categories and social forms from the real material limits and tendencies of a rapidly changing PRC society.
The Willingness to Pay for Diversification
Authors: Mahmoud Ola 
Published: October 2021

Diversification is a fundamental concept in economics and finance. This paper argues that decision makers have an intrinsic preference for diversification that is responsive to cost and that this willingness to pay for diversification is driven by risk aversion and loss aversion. In an experiment replicating a portfolio choice problem, the value of diversification is estimated to be at 5% of the initial endowment of approximately $100. Moreover, risk-averse and loss-averse individuals are willing to pay more for diversification. These findings point to the idea that diversification is a fundamental preference and may help explain portfolio choice anomalies such as irrational diversification, the diversification bias, and overdiversification. This paper was accepted by Tomasz Piskorski, finance.
Resource Allocation with Sigmoidal Demands: Mobile Healthcare Units and Service Adoption
Authors: Alban Andres , Blaettchen Philippe , de Vries Harwin , Van Wassenhove Luk N. 
Published: October 2021

Problem definition: Achieving broad access to health services (a target within the sustainable development goals) requires reaching rural populations. Mobile healthcare units (MHUs) visit remote sites to offer health services to these populations. However, limited exposure, health literacy, and trust can lead to sigmoidal (S-shaped) adoption dynamics, presenting a difficult obstacle in allocating limited MHU resources. It is tempting to allocate resources in line with current demand, as seen in practice. However, to maximize access in the long term, this may be far from optimal, and insights into allocation decisions are limited. Academic/practical relevance: We present a formal model of the long-term allocation of MHU resources as the optimization of a sum of sigmoidal functions. We develop insights into optimal allocation decisions and propose pragmatic methods for estimating our model’s parameters from data available in practice. We demonstrate the potential of our approach by applying our methods to family planning MHUs in Uganda. Methodology: Nonlinear optimization of sigmoidal functions and machine learning, especially gradient boosting, are used. Results: Although the problem is NP-hard, we provide closed form solutions to particular cases of the model that elucidate insights into the optimal allocation. Operationalizable heuristic allocations, grounded in these insights, outperform allocations based on current demand. Our estimation approach, designed for interpretability, achieves better predictions than standard methods in the application. Managerial implications: Incorporating the future evolution of demand, driven by community interaction and saturation effects, is key to maximizing access with limited resources. Instead of proportionally assigning more visits to sites with high current demand, a group of sites should be prioritized. Optimal allocation among prioritized sites aims at equalizing demand at the end of the planning horizon. Therefore, more visits should generally be allocated to sites where the cumulative demand potential is higher and counterintuitively, often those where demand is currently lower. History: This paper has been accepted for the Manufacturing & Service Operations Management Special Section on Responsible Research in Operations Management. Supplemental Material: The e-companion is available at https://doi.org/10.1287/msom.2021.1020 .