bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Phenotypic Difference of IgA Nephropathy and its Race/Gender-dependent Molecular Mechanisms
Authors: Suzuki Yusuke , Monteiro Renato C. , Coppo Rosanna , Suzuki Hitoshi 
Published: May 2021

Abstract
IgA nephropathy (IgAn), defined by the pre dominant de position of IgA in the glomerular mesangium, is the most common form of GN throughout the world. However, its incidence, sex distribution, clinical presentation, and progression and pathogenic initiating factors are largely variable and do not fit such a simple definition. To assess the heterogeneity of this disease, we recently conducted a clinical survey on the presentation and clinical management of patients with IgAn in Europe and Japan. This clinical survey highlights similarities and differences in patients from different cont inents. The survey revealed obvious differences between nations in the frequency of gastrointestinal complications, including inflammatory bowel diseases (IBD) and celiac disease, which were more frequent in European patients. Such findings are compatible with susceptibility loci related to intestinal immunity and IBD in recent genome wide association studies (GWAS) on IgAn. However, most of the molecules in these mucosal-related loci fulfill the immunologic function not only of gut-associated lymphoid tissue (GALT), but also nasopharyngeal/bronchial-associated lymphoid tissues (NALT/BALT). Indeed, a similar frequency of macrohematuria coinciding with upper respiratory infection, a hallmark manifestation of this disease, was found in the survey, emphasizing the pathogenic roles of these molecules in the NALT/BALT of patients with IgAn. Recent experimental and clinical studies including GWAS on multiple common infections and IBD indicate immune crosstalk between GALT and NALT/BALT, and some related mediators, such as TNF superfamily ligands (APRIL/BAFF). This review explains the epidemiologic heterogeneity of this disease with the clinical survey, and discusses race and sex-dependent molecular mechanisms.
Potassium Cyanide (KCN) Content in Coral Reefs and Its Effect on The Abundance of Indicator-Fishes in The Anambas Islands
Authors: Permana Rizki Dimas , Sunarto Sunarto , Harahap Syawalludin Alisyahbana , Riyantini Indah , Ilham Yuwanda 
Published: May 2021

The coral reef ecosystem has been continuously degraded in various parts of Indonesia, including the Anambas Islands. This research aimed to discover the content of Potassium Cyanide (KCN) accumulated on corals and the effect on indicator fishes abundance in the Anambas Islands. This research was conducted at 25 observation stations in the Anambas Islands National Marine Protected Area. The potassium cyanide (KCN) content was tested with the principle of titration and distillation. The coral samples used ranged from 10-20 g diluted in 100-200 ml distilled water. The method used to determine the abundance of indicator fish was underwater visual census or UVC, which recorded fish in every station. This research recorded 307 fish individuals from 14 species of the Chaetodontidae family. Potassium Cyanide's content on corals was high ranging from 0,009-0,032 mg/L with an average 0,0205 mg/L. We concluded that there was a negative correlation between the content of Potassium Cyanide (KCN) on corals and indicator fishes abundance, which means the higher the Potassium Cyanide content (KCN) is on corals, the lower the indicator fishes abundance will point out.
Articulating Os Intermetatarsium with painful ganglion cyst
Authors: Yaacoub Celestie , Kanj Ahmad , Eljebai Malak , Rouhana Georges , Kanj Ali 
Published: May 2021

Objective: Sesamoid and accessory bones are commonly found in the foot and ankle with varying incidence. The Os intermetatarsium, located between the medial cuneiform and the base of the first and second metatarsal, occurs rarely and is frequently asymptomatic. Few symptomatic cases of this condition are reported in the literature. The development of synovial ganglion cyst over an os intermetatarsium is a more occasional finding not clearly reported in the literature.
Case: Here we report the case of a 22 year old female presenting with pain and localized swelling in the dorsum of the midfoot who was found to have a ganglion cyst emerging from an articulating os intermetatarsium.
Conclusion: Although not a common entity, an Os intermetarsium, with its associated complications, can be one of the causes of dorsal foot pain.
SOSIALISASI DAN PSIKOEDUKASI KESEHATAN MENTAL PADA MASYARAKAT KOTA SURABAYA
Authors: Wongpy Novensia , Virlia Stefani 
Published: May 2021

Kesehatan mental dan berbagai permasalahan gangguan mental merupakan salah satu aspek dalam individu yang perlu diperhatikan lebih lanjut. Data dari berbagai survei dan penelitian menunjukkan adanya peningkatan jumlah masyarakat yang mengalami gangguan mental. Kondisi masyarakat dengan anyaknya stigma negatif terkait kesehatan mental dan kurangnya pengetahuan masyarakat membuat masalah-masalah terkait kesehatan mental menjadi lebih buruk dan semakin sulit ditangani. Tujuan dari program ini adalah untuk menigkatkan pengetahuan masyarakat terkait kesehatan mental agar mampu mengurangi stigma negatif, meningkatkan sikap yang positif akan kesehatan mental dan memiliki kesadaran akan pentingnya mempertahankan mental yang sehat. Metode pelaksanaan program yang dipilih adalah dengan memberikan screening kesehatan mental, psikoedukasi dan meditasi bagi masyarakat. Hasil evaluasi dari pelaksanaan program menunjukkan bahwa program yang dirancang efektif menigkatkan pengetahuan, meningkatkan sikap positif masyarakat akan kesehatan mental juga kesadaran masyarakat akan kondisi kesehatan mental mereka masing-masing.
Resonant Chains of Exoplanets: Libration Centers for Three-body Angles
Authors: Siegel Jared C. , Fabrycky Daniel 
Published: May 2021

Abstract
Resonant planetary systems contain at least one planet pair with orbital periods librating at a near-integer ratio (2/1, 3/2, 4/3, etc.) and are a natural outcome of standard planetary formation theories. Systems with multiple adjacent resonant pairs are known as resonant chains and can exhibit three-body resonances—characterized by a critical three-body angle. Here we study three-body angles as a diagnostic of resonant chains through tidally damped N-body integrations. For each combination of the 2:1, 3:2, 4:3, and 5:4 mean motion resonances (the most common resonances in the known resonant chains), we characterize the three-body angle equilibria for several mass schemes, migration timescales, and initial separations. We find that under our formulation of the three-body angle, which does not reduce coefficients, 180° is the preferred libration center, and libration centers shifted away from 180° are associated with nonadjacent resonances. We then relate these angles to observables, by applying our general results to two transiting systems: Kepler-60 and Kepler-223. For these systems, we compare N-body models of the three-body angle to the zeroth order in e approximation accessible via transit phases, used in previous publications. In both cases, we find the three-body angle during the Kepler observing window is not necessarily indicative of the long-term oscillations and stress the role of dynamical models in investigating three-body angles. We anticipate our results will provide a useful diagnostic in the analysis of resonant chains.
The Fundamental Plane in the LEGA-C Survey: Unraveling the M/L Ratio Variations of Massive Star-forming and Quiescent Galaxies at z ∼ 0.8
Authors: de Graaff Anna , Bezanson Rachel , Franx Marijn , van der Wel Arjen , Holden Bradford , van de Sande Jesse , Bell Eric F. , D’Eugenio Francesco , Maseda Michael V. , Muzzin Adam , Sobral David , Straatman Caroline M. S. , Wu Po-Feng 
Published: May 2021

Abstract
We explore the connection between the kinematics, structures and stellar populations of massive galaxies at 0.6 < z < 1.0 using the fundamental plane (FP). Combining stellar kinematic data from the Large Early Galaxy Astrophysics Census (LEGA-C) survey with structural parameters measured from deep Hubble Space Telescope imaging, we obtain a sample of 1419 massive (

log
(

M

*

/

M

⊙

)
>
10.5

) galaxies that span a wide range in morphology, star formation activity, and environment, and therefore is representative of the massive galaxy population at z ∼ 0.8. We find that quiescent and star-forming galaxies occupy the parameter space of the g-band FP differently and thus have different distributions in the dynamical mass-to-light ratio (M
dyn/L

g
), largely owing to differences in the stellar age and recent star formation history, and to a lesser extent, the effects of dust attenuation. In contrast, we show that both star-forming and quiescent galaxies lie on the same mass FP at z ∼ 0.8, with a comparable level of intrinsic scatter about the plane. We examine the variation in M
dyn/M
* through the thickness of the mass FP, finding no significant residual correlations with stellar population properties, Sérsic index, or galaxy overdensity. Our results suggest that, at fixed size and velocity dispersion, the variations in M
dyn/L

g
of massive galaxies reflect an approximately equal contribution of variations in M
*/L

g
, and variations in the dark matter fraction or initial mass function.
AGNs on the Move: A Search for Off-nuclear AGNs from Recoiling Supermassive Black Holes and Ongoing Galaxy Mergers with the Zwicky Transient Facility
Authors: Ward Charlotte , Gezari Suvi , Frederick Sara , Hammerstein Erica , Nugent Peter , van Velzen Sjoert , Drake Andrew , García-Pérez Abigail , Oyoo Immaculate , Bellm Eric C. , Duev Dmitry A. , Graham Matthew J. , Kasliwal Mansi M. , Kaye Stephen , Mahabal Ashish A. , Masci Frank J. , Rusholme Ben , Soumagnac Maayane T. , Yan Lin 
Published: May 2021

Abstract
A supermassive black hole (SMBH) ejected from the potential well of its host galaxy via gravitational wave recoil carries important information about the mass ratio and spin alignment of the pre-merger SMBH binary. Such a recoiling SMBH may be detectable as an active galactic nucleus (AGN) broad-line region offset by up to 10 kpc from a disturbed host galaxy. We describe a novel methodology using forward modeling with The Tractor to search for such offset AGNs in a sample of 5493 optically variable AGNs detected with the Zwicky Transient Facility (ZTF). We present the discovery of nine AGNs that may be spatially offset from their host galaxies and are candidates for recoiling SMBHs. Five of these offset AGNs exhibit double-peaked broad Balmer lines, which may have arisen from unobscured accretion disk emission, and four show radio emission indicative of a relativistic jet. The fraction of double-peaked emitters in our spatially offset AGN sample is significantly larger than the 16% double-peaked emitter fraction observed for ZTF AGNs overall. In our sample of variable AGNs we also identified 52 merging galaxies, including a new spectroscopically confirmed dual AGN. Finally, we detected the dramatic rebrightening of SDSS 1133, a previously discovered variable object and recoiling SMBH candidate, in ZTF. The flare was accompanied by the reemergence of strong P Cygni line features, indicating that SDSS 1133 may be an outbursting luminous blue variable star.
3D Convection-resolving Model of Temperate, Tidally Locked Exoplanets
Authors: Lefèvre Maxence , Turbet Martin , Pierrehumbert Raymond 
Published: May 2021

Abstract
A large fraction of known terrestrial-size exoplanets located in the habitable zone of M-dwarfs are expected to be tidally locked. Numerous efforts have been conducted to study the climate of such planets, using in particular 3D global climate models (GCMs). One of the biggest challenges in simulating such an extreme environment is to properly represent the effects of sub-grid convection. Most GCMs use either a simplistic convective-adjustment parameterization or sophisticated (e.g., mass flux scheme) Earth-tuned parameterizations. One way to improve the representation of convection is to study convection using numerical convection-resolving models (CRMs), with a fine spatial resolution. In this study, we developed a CRM coupling the non-hydrostatic dynamical core Advanced Research Weather-Weather Research and Forecast model with the radiative transfer and cloud/precipitation models of the Laboratoire de Météorologie Dynamique generic climate model to study convection and clouds on tidally locked planets, with a focus on Proxima b. Simulations were performed for a set of three surface temperatures (corresponding to three different incident fluxes) and two rotation rates, assuming an Earth-like atmosphere. The main result of our study is that while we recover the prediction of GCMs that (low-altitude) cloud albedo increases with increasing stellar flux, the cloud feedback is much weaker due to transient aggregation of convection leading to low partial cloud cover.
Pebble Trapping in Vortices: Three-dimensional Simulations
Authors: Raettig Natalie , Lyra Wladimir , Klahr Hubert 
Published: May 2021

Abstract
Disk vortices have been heralded as promising routes for planet formation due to their ability to trap significant amounts of pebbles. While the gas motions and trapping properties of two-dimensional vortices have been studied in enough detail in the literature, pebble trapping in three dimensions has received less attention, due to the higher computational demand. Here we use the Pencil Code to study 3D vortices generated by convective overstability and the trapping of solids within them. The gas is unstratified whereas the pebbles settle to the midplane due to vertical gravity. We find that for pebbles of normalized friction times of

St
=
0.05

and

St
=
1

, and dust-to-gas ratio

ε
=
0.01

, the vortex column in the midplane is strongly perturbed. Yet when the initial dust-to-gas ratio is decreased the vortices remain stable and function as efficient pebble traps. Streaming instability is triggered even for the lowest dust-to-gas ratio (

ε

0

=

10

−
4

) and smallest pebble sizes (

St
=
0.05

) we assumed, showing a path for planetesimal formation in vortex cores from even extremely subsolar metallicity. To estimate if the reached overdensities can be held together solely by their own gravity we estimate the Roche density at different radii. Depending on disk model and radial location of the pebble clump we do reach concentrations higher than the Roche density. We infer that if self-gravity was included for the pebbles then gravitational collapse would likely occur.
XMM-Newton X-Ray Observations of the Unusual Wolf–Rayet Star WR 66
Authors: Skinner Stephen L. , Schmutz Werner , Güdel Manuel , Zhekov Svetozar A. 
Published: May 2021

Abstract
We summarize results of an XMM-Newton X-ray observation of the WN8h-type Wolf–Rayet star WR 66 which shows unusual 3.5–4.1 hr optical variations. One possible explanation is a compact companion (cc) which, if present, could give rise to luminous X-ray emission. WR 66 was marginally detected and its inferred X-ray luminosity (L

x
) is orders of magnitude below that expected from wind accretion onto a neutron star, but is comparable to that of the WN8h stars WR 16 and WR 124. If luminous X-ray emission from an accreting WR+cc system is present then it is absorbed and escapes detection. Other explanations of the faintly detected X-ray emission of WN8h stars are not ruled out.
A striking new species of Dolichomitus Smith, 1877 (Hymenoptera: Ichneumonidae; Pimplinae) from South America
Authors: Di Giovanni Filippo , Pádua Diego , Araujo Rodrigo , Santos Alvaro , Sääksjärvi Ilari 
Published: May 2021

Dolichomitus Smith, 1877 is a genus of Darwin wasps characterised by their large bodies and long ovipositors, that includes more than 75 species worldwide, 20 of which occur in the Neotropical Region. Due to recent efforts, the number of species of this genus continues to increase in South America.
A new iridescent species of Pimplinae, Dolichomitus meii sp. nov., is described and illustrated. It was discovered from the biological station of Yanayacu located in the north-eastern slopes of the tropical Andes. It may be separated from all other species of Dolichomitus Smith by the striking colour pattern and apically strongly decurved ovipositor.
Mafusol and its combination with REXOD as correctors of reduced blood circulation in the skin associated with normoglycemia or diabetes mellitus complicated by exogenous hypercholesterolemia
Authors: Gulevskaya Olga N. , Galenko-Yaroshevsky Pavel A. , Lebedeva Svetlana A. , Sukoyan Galina  V. , Pavlyuchenko Ivan I. , Zelenskaya Anait V. , Uvarov Alexandr V. , Tseluiko Kristina V. , Popkov Viktor L. , Zadorozhniy Andrey V. , Chuyan Elena N. , Ravaeva Marina Yu. , Galenko-Yaroshevsky Jr Pavel A. 
Published: May 2021

Introduction: The search for and development of new highly active medications and their combinations of the appropriate direction of action remains an urgent problem due to the complications of diabetes mellitus, especially burdened with atherosclerosis, including skin and vascular lesions.
Materials and methods: The acute toxicity, histoprotective and dermatoprotective effects of mafusol, rexod, alprostadil and their combinations were studied in male rats with normoglycemia and alloxan diabetes complicated by exogenous hypercholesterolemia.
Results: The combination of mafusol with rexod is less toxic than mafusol. In arteriovenous insufficiency of the tail, ischemia of the skin fold and skin flap, mafusol (6.25, 12.5 and 25.0 mg/kg in terms of fumarate), rexod (0.01 and 0.02 mg/kg) and especially their combination (6.25 and 0.01 mg/kg) have significant histoprotective, dermatoprotective, hypoglycemic and lipid-lowering effects, both in normoglycemia and alloxan diabetes complicated by exogenous hypercholesterolemia. Alprostadil (10 mg/kg) and especially its combination with mafusol (6.25 mg/kg) have a dermatoprotective effect.
Discussion: Rexod reduces the acute toxicity of mafusol. The dermatoprotective effect of mafusol, rexod and, to a greater extent, their combination may be associated with increased microhemocirculation, antihypoxic properties and activation of energy processes in the skin, normalization of carbohydrate and lipid metabolism in alloxan diabetes, complicated by exogenous hypercholesterolemia, increased reserve capacity of the antioxidant system, and possibly with the ability of mafusol and rexod to reduce blood viscosity and improve rheological properties of the blood. The combination of mafusol with alprostadil increases the dermatoprotective activity of the latter.
Conclusion: Combinations of mafusol with rexod and alprostadil can be recommended for clinical study as dermatoprotective agents for treating traumatic injuries and diabetes mellitus complicated by atherosclerosis.
« L’ivresse patrimoniale », et après ?
Authors: Laurent Natacha 
Published: May 2021

Alors que l’accès aux films anciens était autrefois réservé à certains lieux spécifiques, le patrimoine cinématographique n’a jamais été aussi visible, ni apparemment aussi accessible, qu’aujourd’hui. Comment interpréter cette « ivresse patrimoniale » ? Est-elle vraiment une victoire du patrimoine cinématographique ? L’analyse de cette visibilité inédite montre qu’elle est le symptôme d’un bouleversement majeur : l’entrée en scène du marché, qui s’accompagne d’un discours rassurant et consensuel. Mais appliquer systématiquement aux films d’hier une logique marchande a des conséquences tant sur l’évolution des cinémathèques et archives du film que sur notre conception et nos pratiques du patrimoine cinématographique.
The course-of-action research program : historical and conceptual landmarks
Authors: Poizat Germain , Martin Julia San 
Published: May 2021

The “course of action” empirical and technological research program was developed in the field of ergonomics during the 1980s and 1990s. It was then extended to other fields of research and action beyond the boundaries of ergonomics. This contribution proposes an archeology of knowledge with the aim of gaining an understanding not only of the "course of action" research program (and its concreteness), but also of the notions/concepts/methods/models that it proposes for both analysis and design. By rapidly scanning both the history and the conceptual universe of the “course of action” research program, this article aims (1) to point out the main empirical and technological contributions of this program and the potential it still holds (for work/activity analysis and for design), and (2) to help to make sense of certain concepts and analytical notions by mentioning the context of their emergence and evolutions.
Déroutages : trajectoires des œuvres de Lasar Segall confisquées par « l’Action contre l’art dégénéré »
Authors: Caires Daniel Rincon 
Published: May 2021

Cet article présente les résultats d’une enquête sur les trajectoires de 58 œuvres d’art de Lasar Segall confisquées dans le cadre de « l’Action contre l’art dégénéré » menée par les nazis. Le cas particulier de l’artiste russe permet d’observer ces types de politiques de dénonciations et de spoliations avant, pendant et après le régime hitlérien sous un autre angle. Le devenir des œuvres de Segall qui étaient présentes dans les collections publiques allemandes avant 1937 éclaire les dynamiques culturelles, politiques et sociales qui ont secoué l’Allemagne entre 1918 et 1945.
Quel(s) besoin(s) d’accomplissement pour quelles carrières ? Une exploration dans le contexte tunisien pour mieux comprendre l’attrait pour la carrière entrepreneuriale
Authors: Taktak Kallel Ilia 
Published: May 2021

Le besoin d’accomplissement est reconnu pour être l’un des plus puissants moteurs de l’activité humaine. Il est largement admis, après les travaux de Mc Clelland (1961), que les entrepreneurs sont particulièrement habités par ce besoin. Ce dernier est-il l’apanage de certains individus ? S’exprime-t-il de la même manière d’une culture à une autre ? Si le travail est l’occasion de revisiter ces différentes questions, l’ambition est de comprendre quels besoins psychologiques et valeurs sont congruents avec quelles préférences de carrière dans le contexte tunisien et – in fine – de cerner certains des moteurs qui peuvent expliquer l’attrait pour la carrière entrepreneuriale. Pour ce faire, une enquête par questionnaire a été menée auprès de 213 étudiants d’une école de commerce à Tunis. Les résultats obtenus révèlent notamment que le besoin d’accomplissement est surtout relié aux situations d’indécision en matière de préférences de carrière, alors que l’attrait pour la carrière entrepreneuriale va significativement de pair avec la recherche d’une certaine qualité de vie, ce qui nous a amené à avancer l’idée d’une « féminisation » des valeurs de ceux qui expriment une préférence pour la création d’entreprise, même si cette dernière reste une carrière largement masculine.