bluuebunny/crossref_metadata_2025_split huggingface dataset:
Slow Cortical Potential Versus Live Z-score Neurofeedback in Children and Adolescents with ADHD: A Multi-arm Pragmatic Randomized Controlled Trial with Active and Passive Comparators
Authors: Hasslinger John , Bölte Sven , Jonsson Ulf 
Published: September 2021

AbstractNeurofeedback (NF) as a treatment for Attention Deficit Hyperactivity Disorder (ADHD) has been evaluated in several trials, but the specificity and generalizability of effects remain unclear. This four-arm randomized controlled trial evaluated the efficacy of Slow Cortical Potential (SCP; standard NF protocol) and Live Z-score (LZS; non-standard NF protocol) delivered in high-frequency format (five sessions per week during five weeks), compared to Working-memory training (WMT; active comparator) and Treatment-as-usual (TAU; passive comparator). N = 202 children/adolescents aged 9 to 17 years with ADHD participated. The primary outcome measure was multi-report (self-, teacher-, and parent-report) ADHD core symptoms on the Conners-3, assessed at baseline, posttreatment, and 6-months follow-up. Data were analyzed using a linear mixed model. Between-group differences were scarce and did not show a distinct pattern. Superiority of LZS over TAU at endpoint were observed for teacher-rated measures only, while significant differences between SCP and TAU were restricted to posttreatment measurements. Contrary to our expectations, LZS outperformed SCP at endpoint for teacher-rated hyperactivity (-5.37; 95% CI: -10.14 to -0.60; p = .028; d = -.36) and overall ADHD symptoms (-2.20; -4.18 to -0.22; p = .030; d = -.41). There was no indication that either form of NF was superior to WMT. No severe adverse events were reported during the trial, whereas transient stress-related problems were quite frequent. Overall, the results from this pragmatic trial do not provide convincing support for broad implementation of NF in child and adolescent psychiatric services. Future research should try to clarify for whom and under what circumstances NF might be a viable treatment option.
Figure Disembedding: The Gottschaldt’s Hidden Figure Test in Children with Typical Development and Autism
Authors: Conson Massimiliano , Siciliano Mattia , Trojano Luigi , Zoccolotti Pierluigi , Zappullo Isa , Baiano Chiara , Caputo Giovanni , Russo Alessandro ,   the LabNPEE group, Cecere Roberta , Di Rosa Alessandro , Esposito Giovanna , Milo Rosa , Polito Francesco , Rauso Barbara , Vela Maria , Santangelo Gabriella 
Published: September 2021

AbstractIn two studies, we used the Gottschaldt’s Hidden Figure Test (GHFT) for assessing figure disembedding ability in children aged 7–11. Study 1 demonstrated in a large sample of typically developing children that GHFT accuracy and time scores differed across age groups, without sex and socioeconomic differences. Thus, we provided normative data only taking into account children’s age. In Study 2, GHFT normative values were used to assess children with autism, who were also compared with a closely age-matched group of typical controls. Children with autism achieved time scores at or above the 50th centile and significantly differed from the controls for time score. The GHFT seems a valuable tool for defining the cognitive profile of children with autism.
“Looking at” Negation: Faster Processing for Symbolic Rather Than Iconic Representations
Authors: Orenes Isabel 
Published: September 2021

AbstractMany studies have shown the double processing of negation, suggesting that negation integration into sentence meaning is delayed. This contrasts with some researches that have found that such integration is rather immediate. The present study contributes to this debate. Affirmative and negative compound sentences (e.g., “because he was not hungry, he did not order a salad”) were presented orally in a visual world paradigm while four printed words were on the screen: salad, no salad, soup, and no soup. The eye-tracking data showed two different fixation patterns for negative causal assertions, which are linked to differences in the representation and inferential demands. One indicates that negation is integrated immediately, as people look at the explicit negation (e.g., no salad) very early. The other, in which people look at the alternate (e.g., soup) much later, indicates that what is delayed in time is the representation of the alternate. These results support theories that combine iconic and symbolic representations, such as the model theory.
Implicit algorithms for eigenvector nonlinearities
Authors: Jarlebring Elias , Upadhyaya Parikshit 
Published: September 2021

AbstractWe study and derive algorithms for nonlinear eigenvalue problems, where the system matrix depends on the eigenvector, or several eigenvectors (or their corresponding invariant subspace). The algorithms are derived from an implicit viewpoint. More precisely, we change the Newton update equation in a way that the next iterate does not only appear linearly in the update equation. Although the modifications of the update equation make the methods implicit, we show how corresponding iterates can be computed explicitly. Therefore, we can carry out steps of the implicit method using explicit procedures. In several cases, these procedures involve a solution of standard eigenvalue problems. We propose two modifications, one of the modifications leads directly to a well-established method (the self-consistent field iteration) whereas the other method is to our knowledge new and has several attractive properties. Convergence theory is provided along with several simulations which illustrate the properties of the algorithms.
How does qualitative data collection modality affect disclosure of sensitive information and participant experience? Findings from a quasi-experimental study
Authors: Namey Emily , Guest Greg , O’Regan Amy , Godwin Christine L. , Taylor Jamilah , Martinez Andres 
Published: September 2021

AbstractFocus groups (FGs) and individual interviews (IDIs) can be conducted in-person or in several different online contexts. We conducted a quasi-experimental study and assessed sharing of sensitive or dissenting information and participant comfort in FGs and IDIs across four modalities: (1) in-person, (2) online video-based, (3) online chat-based (synchronous), and (4) online email/message board-based (asynchronous). Participants were systematically assigned to one of the four modalities and randomized to one of 24 FGs or 48 IDIs (N = 171). The study topic was medical risk during pregnancy. All participants also completed a survey on their perceptions of the data collection process. We found no significant difference in the frequency of disclosure of sensitive information by modality. Text-based FGs (chat and message board) were more likely to contain dissenting opinions than visually-based FGs (in-person and video). Participants also reported feeling less rapport and personal comfort in sharing information in the FG video modality than other modalities. These findings provide initial data that can guide researchers in choosing among data collection modalities to maximize participant engagement and comfort.
Exploring the effects of climate-related financial policies on carbon emissions in G20 countries: a panel quantile regression approach
Authors: D’Orazio Paola , Dirks Maximilian W. 
Published: September 2021

AbstractThis paper studies the effects of financial development, economic growth, and climate-related financial policies on carbon emissions for G20 countries. The focus is particularly on financial policies implemented to scale up green finance and address climate-related financial risks from 2000 to 2017 and represent this paper’s value added. The empirical results obtained by relying on the panel quantile regression approach indicate that the impacts of the different explanatory variables on carbon emission are heterogeneous. Specifically, the effect of the stock of short-term financial policies on carbon emissions is negative, and its effect becomes smaller at higher quantiles. The stock of long-term policies also shows significant negative coefficients, but its impact is stronger for higher quantiles. No significance is reported for the lowest quantile. Financial development contributes to improving environmental quality, and its impact is larger in higher emission countries. Energy consumption increases carbon emissions, with the strongest effects occurring at higher quantiles. Our results also support the validity of the EKC relationship and positive effects of GDP and population on high carbon emissions levels. Estimation results are robust to alternative model specifications and after controlling for the role played by adopting international climate change mitigation policies as proxied by the adoption of the Kyoto Protocol.
Status of short-chain chlorinated paraffins in matrices and research gap priorities in Africa: a review
Authors: Nevondo Vhodaho , Okonkwo Okechukwu Jonathan 
Published: September 2021

AbstractChlorinated paraffins (CPs) have been applied as additives in a wide range of consumer products, including polyvinyl chloride (PVC) products, mining conveyor belts, paints, sealants, adhesives and as flame retardants. Consequently, CPs have been found in many matrices. Of all the CP groups, short-chain chlorinated paraffins (SCCPs) have raised an alarming concern globally due to their toxicity, persistence and long-range transportation in the environment. As a result, SCCPs were listed in the Stockholm Convention on Persistent Organic Pollutants (POPs) in May 2017. Additionally, a limit for the presence of SCCPs in other CP mixtures was set at 1% by weight. CPs can be released into the environment throughout their life cycle; therefore, it becomes crucial to assess their effects in different matrices. Although about 199 studies on SCCP concentration in different matrices have been published in other continents; however, there are scarce/or limited studies on SCCP concentration in Africa, particularly on consumer products, landfill leachates and sediment samples. So far, published studies on SCCP concentration in the continent include SCCPs in egg samples, e-waste recycling area and indoor dust in Ghana and South Africa, despite absence of any production of SCCPs in Africa. However, there still remains a huge research gap in the continent of Africa on SCCPs. Consequently, there is a need to develop robust SCCP inventories in Africa since the Stockholm Convention has already developed guidance document in this respect. This review, therefore, examines the state of knowledge pertaining to the levels and trends of these contaminants in Africa and further provides research gaps that need to be considered in order to better understand the global scale of the contaminant.
Establishing an institutional reverse total shoulder arthroplasty registry
Authors: Kriechling Philipp , Waltenspül Manuel , Bouaicha Samy , Wieser Karl 
Published: September 2021

Abstract
Background
The number of implanted reverse total shoulder arthroplasties (RTSA) is increasing worldwide. To improve patient care, institutional and national arthroplasty registries are being established worldwide to record outcome data. This article aims to describe the setup of an RTSA database in a high-volume university orthopedic hospital.

Methods
All patients who received an RTSA at the authors’ tertiary referral hospital have been followed and individual datasets have been systematically recorded in a REDCap database since 2005. The data are captured longitudinally as a primary preoperative survey and as a regular or irregular postoperative follow-up. All baseline demographic data, patient history, surgical details, arthroplasty details, adverse events, and radiographic and clinical outcome scores (Constant–Murley score, Subjective Shoulder Value, range of motion) are recorded.

Results
A total of 1433 RTSA were implanted between January 2005 and December 2020. Of these, 1184 (83%) were primary implantations and 249 (17%) were secondary cases. The cohort had a mean age of 70 ± 10 years, was 39% male, and was classified ASA II in 59%. The lost to follow-up rate was 18% after 2 years, 22% after 5 years, and 53% after 10 years. The overall complication rate with 2 years minimum follow-up was 18% (156/854 shoulders) with reintervention in 10% (82/854 shoulders).

Conclusion
A well-managed institutional arthroplasty registry, including structured clinical and radiological follow-up assessments, offers the opportunity for high-quality long-term patient and arthroplasty outcome analysis. Such data are not only helpful for analyzing patient outcome and implant survival, but will be increasingly important to justify our daily clinical practice against different stakeholders in the various health care systems.
The Jejunojejunostomy: an Achilles Heel of the Roux-en-Y Gastric Bypass Construction
Authors: Hedberg Suzanne , Xiao Yao , Klasson Adam , Maleckas Almantas , Wirén Mikael , Thorell Anders , Laurenius Anna , Engström My , Olbers Torsten 
Published: September 2021

Abstract
Background
Laparoscopic Roux-en-Y gastric bypass (RYGB) has for long been the gold standard technique in bariatric surgery, especially in the Scandinavian countries. In a tertiary hospital setting, we observed an increasing number of patients with postprandial abdominal pain and nausea, often associated with complex hypoglycemia.

Objectives
The present study aimed to characterize the clinical patterns, patient characteristics, and clinical outcomes after surgical revision of dysfunctional RYGB at Sahlgrenska University Hospital in Gothenburg, Sweden.

Methods
This cohort study included patients with RYGB who underwent revision of the jejunojejunostomy (JJ) after 2013. Information was obtained by reviewing medical records and performing complementary interviews.

Results
Laparoscopic revisional surgery was performed in 115 cases with either adhesiolysis or total revision of the JJ (mean age 41 years, range 19–67 years; 90% women). The median time to assessment after the last revision was 33 months (range 12–75 months). Forty-four (38%) patients reported that they were symptom-free long-term after the intervention, and 32 (28%) patients experienced an improvement in the symptoms that were the indication for revision. However, 31 (27%) patients reported no long-term improvement, and half of them (n = 16) subsequently had a reversal of the anatomy. Eight (7%) patients were lost to follow-up.

Conclusions
Dysfunction of the JJ appears to be a relatively common cause of postprandial pain and nausea after ante-colic/ante-gastric RYGB. Most patients with symptoms of dysfunction experienced partial or total relief following revisional surgery, but a substantial minority had persistent problems, with one in five eventually undergoing reversal of the anatomy.

Graphical Abstract
Robot-assisted pancreatic surgery—optimized operating procedures: set-up, port placement, surgical steps
Authors: Felsenstein Matthäus , Hillebrandt Karl H. , Timmermann Lea , Feist Mathilde , Benzing Christian , Schmelzle Moritz , Pratschke Johann , Malinka Thomas 
Published: September 2021

AbstractEven in most complex surgical settings, recent advances in minimal-invasive technologies have made the application of robotic-assisted devices more viable. Due to ever increasing experience and expertise, many large international centers now offer robotic-assisted pancreatic surgery as a preferred alternative. In general however, pancreatic operations are still associated with high morbidity and mortality, while robotic-assisted techniques still require significant learning curves. As a prospective post-marketing trial, we have established optimized operating procedures at our clinic. This manuscript intends to publicize our standardized methodology, including pre-operative preparation, surgical set-up as well as the surgeons’ step-by-step actions when using pancreatic-assisted robotic surgery. This manuscript is based on our institutional experience as a high-volume pancreas operating center. We introduce novel concepts that should standardize, facilitate and economize the surgical steps in all types of robotic-assisted pancreatic surgery. The “One Fits All” principle enables single port placement irrespective of the pancreatic procedure, while the “Reversed 6-to-6 Approach” offers an optimized manual for pancreatic surgeons using the robotic console. Novel and standardized surgical concepts could guide new centers to establish a robust, efficient and safe robotic-assisted pancreatic surgery program.
On a Class of Integral Systems
Authors: Derkach Volodymyr , Strelnikov Dmytro , Winkler Henrik 
Published: September 2021

AbstractWe study spectral problems for two-dimensional integral system with two given non-decreasing functions R, W on an interval [0, b) which is a generalization of the Krein string. Associated to this system are the maximal linear relation $$T_{\max }$$

T
max

and the minimal linear relation $$T_{\min }$$

T
min

in the space $$L^2(dW)$$

L
2

(
d
W
)

which are connected by $$T_{\max }=T_{\min }^*$$

T
max

=

T

min

∗

. It is shown that the limit point condition at b for this system is equivalent to the strong limit point condition for the linear relation $$T_{\max }$$

T
max

. In the limit circle case the Evans–Everitt condition is proved to hold on a subspace $$T_N^*$$

T
N
∗

of $$T_{\max }$$

T
max

characterized by the Neumann boundary condition at b. The notion of the principal Titchmarsh–Weyl coefficient of this integral system is introduced. Boundary triple for the linear relation $$T_{\max }$$

T
max

in the limit point case (and for $$T_{N}^*$$

T

N

∗

in the limit circle case) is constructed and it is shown that the corresponding Weyl function coincides with the principal Titchmarsh–Weyl coefficient of the integral system. The notion of the dual integral system is introduced by reversing the order of R and W and the formula relating the principal Titchmarsh–Weyl coefficients of the direct and the dual integral systems is proved. For every integral system with the principal Titchmarsh–Weyl coefficients q a canonical system is constructed so that its Titchmarsh–Weyl coefficient Q is the unwrapping transform of q: $$Q(z)=z q(z^2)$$

Q

(
z
)

=
z
q

(

z
2

)

.
Sex Differences in Hypertrophic Cardiomyopathy: Interaction With Genetics and Environment
Authors: Butters Alexandra , Lakdawala Neal K. , Ingles Jodie 
Published: September 2021

Abstract
Purpose of Review
We explore the sex-specific interaction of genetics and the environment on the clinical course and outcomes of hypertrophic cardiomyopathy (HCM).

Recent Findings
Women account for approximately one-third of patients in specialist HCM centres and reported in observational studies. As a result, evidence informing clinical guideline recommendations is based predominantly on risk factors and outcomes seen in men. However, disease progression appears to be different between the sexes. Women present at a more advanced stage of disease, are older at diagnosis, have higher symptom burden, carry greater risk for heart failure and are at greater risk of mortality compared to men. Women are more likely to be gene-positive, while men are more likely to be gene-negative. The risk of sudden cardiac death and access to specialised care do not differ between the sexes.

Summary
Reporting sex-disaggregated results is essential to identify the mechanisms leading to sex differences in HCM.
Nested hollow architectures of nitrogen-doped carbon-decorated Fe, Co, Ni-based phosphides for boosting water and urea electrolysis
Authors: Zhang Jie , Huang Shoushuang , Ning Ping , Xin Peijun , Chen Zhiwen , Wang Qing , Uvdal Kajsa , Hu Zhangjun 
Published: September 2021

AbstractTailoring the nanostructure/morphology and chemical composition is important to regulate the electronic configuration of electrocatalysts and thus enhance their performance for water and urea electrolysis. Herein, the nitrogen-doped carbon-decorated tricomponent metal phosphides of FeP4 nanotube@Ni-Co-P nanocage (NC-FNCP) with unique nested hollow architectures are fabricated by a self-sacrifice template strategy. Benefiting from the multi-component synergy, the modification of nitrogen-doped carbon, and the modulation of nested porous hollow morphology, NC-FNCP facilitates rapid electron/mass transport in water and urea electrolysis. NC-FNCP-based anode shows low potentials of 248 mV and 1.37 V (vs. reversible hydrogen electrode) to attain 10 mA/cm2 for oxygen evolution reaction (OER) and urea oxidation reaction (UOR), respectively. In addition, the overall urea electrolysis drives 10 mA/cm2 at a comparatively low voltage of 1.52 V (vs. RHE) that is 110 mV lower than that of overall water electrolysis, as well as exhibits excellent stability over 20 h. This work strategizes a multi-shell-structured electrocatalyst with multi-compositions and explores its applications in a sustainable combination of hydrogen production and sewage remediation.
40 Years Anniversary of Cardiac 123I-mIBG Imaging: State of the Heart
Authors: Verschure D. O. , Nakajima K. , Jacobson A. F. , Verberne H. J. 
Published: September 2021

Abstract
Purpose of Review
This narrative review reflects on the body of evidence on cardiac 123I-mIBG imaging that has accumulated since the introduction in the late 1970s and focusses on to what extent cardiac 123I-mIBG imaging has fulfilled its potential in cardiology especially.

Recent Findings
In contrast to the linear relationship between 123I-mIBG-derived parameters and overall prognosis in heart failure, there seems a “bell-shape” curve for 123I-mIBG-derived parameters and arrhythmic events. In addition, there is a potential clinical role for cardiac 123I-mIBG in optimizing patient selection for expensive devices (i.e., ICD and CRT). This needs of course to be established in future trials.

Summary
Cardiac 123I-mIBG imaging is, despite the numerous of studies, sometimes mistakenly seen as a nice to have technique rather than a must have imaging modality. Although cardiac 123I-mIBG imaging has grown and matured over the years, its full clinical potential has still not been tested to the maximum.
Family screening in patients with isolated bicuspid aortic valve
Authors: Cozijnsen L. , Braam R. L. , Bakker-de Boo M. , Otten A. M. , Post J. G. , Schermer T. , Bouma B. J. , Mulder B. J. M. 
Published: September 2021

Abstract
Aim
To determine the prevalence of undiagnosed bicuspid aortic valve (BAV) and isolated aortic dilatation in first-degree relatives (FDRs) of patients with isolated BAV and to explore the recurrence risk of BAV in different subgroups of probands with BAV. Recent American College of Cardiology (ACC)/American Heart Association (AHA) Guidelines recommend family screening in patients with associated aortopathy only.

Methods
During follow-up visits, patients with isolated BAV received a printed invitation for their FDRs advising cardiac screening.

Results
From 2012–2019, 257 FDRs of 118 adult BAV patients were screened, among whom 63 (53%) index patients had undergone aortic valve surgery (AVS), including concomitant aortic replacement in 25 (21%). Of the non-operated index patients, 31 (26%) had aortic dilatation (> 40 mm). Mean age of the FDRs was 48 years (range 4–83) and 42% were male. The FDR group comprised 20 parents, 103 siblings and 134 offspring. Among these FDRs, 12 (4.7%) had a previously undiagnosed BAV and 23 (8.9%) had an isolated aortic dilatation. FDRs of the probands with previous AVS (n = 147) had a risk ratio for BAV of 2.25 (95% confidence interval (CI) 0.62–8.10). FDRs of the probands with BAV and repaired or unrepaired aortic dilatation (n = 127) had a risk ratio for BAV of 0.51 (95% CI 0.16–1.66).

Conclusion
Screening FDRs of patients with isolated BAV resulted in a reasonable yield of 14% new cases of BAV or isolated aortic dilatation. A trend towards an increased risk of BAV in FDRs was observed in the probands with previous AVS, whereas this risk seemed to be diminished in the probands with associated aortic dilatation. This latter finding does not support the restrictive ACC/AHA recommendation.