bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Method for Performing Forging Operation: A Perspective of Industry 4.0
Authors: Pasi Bhaveshkumar N. , Mahajan Subhash K. , Rane Santosh B. 
Published: January 2021

Background:
Cold forging operation is done on small as well as large scale in manufacturing
industries. These industries are facing problems such as higher rejection rate of the final product, low
productivity, the high number of accidents during production, etc.

Objective:
The purpose of this research work is to develop a Voice-Assisted Forging System (VAFS)
with a lower rejection rate, higher productivity, and lower number of accidents during production.

Methods:
Based on recently published journals and patents, traditional and automatic forging operations,
Industry 4.0, and voice assisted systems are reviewed and VAFS is designed and developed. Then, the
trial is taken on VAFS to investigate its performance. Finally, limitations and future research of the VAFS
are proposed.

Results:
It is found that after implementation of the VAFS the average rejection count is reduced by 90.3
percentage, the operational productivity is increased by 71.2 percentage, and process accuracy is increased
from 92.75 percentage to 99.30 percentage. Also, the number of accidents is reduced to zero. In
comparison with the manual forging operation, the VAFS occupies less space, and it is easy to operate.

Conclusion:
This system will help the workers as well as the owner of industries to create a better man and machine
relationship and to have a human-friendly working environment. VAFS reduces exhaustion and hassle of employees,
components rejection, and energy consumptions in the production line.
Analyzing Digital Evidence From a Telemental Health Platform to Assess Complex Psychological Responses to the COVID-19 Pandemic: Content Analysis of Text Messages
Authors: Hull Thomas D , Levine Jacob , Bantilan Niels , Desai Angel N , Majumder Maimuna S 
Published: January 2021

Background
The novel COVID-19 disease has negatively impacted mortality, economic conditions, and mental health. These impacts are likely to continue after the COVID-19 pandemic ends. There are no methods for characterizing the mental health burden of the COVID-19 pandemic, and differentiating this burden from that of the prepandemic era. Accurate illness detection methods are critical for facilitating pandemic-related treatment and preventing the worsening of symptoms.

Objective
We aimed to identify major themes and symptom clusters in the SMS text messages that patients send to therapists. We assessed patients who were seeking treatment for pandemic-related distress on Talkspace, which is a popular telemental health platform.

Methods
We used a machine learning algorithm to identify patients’ pandemic-related concerns, based on their SMS text messages in a large, digital mental health service platform (ie, Talkspace). This platform uses natural language processing methods to analyze unstructured therapy transcript data, in parallel with brief clinical assessment methods for analyzing depression and anxiety symptoms.

Results
Our results show a significant increase in the incidence of COVID-19–related intake anxiety symptoms (P<.001), but no significant differences in the incidence of intake depression symptoms (P=.79). During our transcript analyses, we identified terms that were related to 24 symptoms outside of those included in the diagnostic criteria for anxiety and depression.

Conclusions
Our findings for Talkspace suggest that people who seek treatment during the pandemic experience more severe intake anxiety than they did before the COVID-19 outbreak. It is important to monitor the symptoms that we identified in this study and the symptoms of anxiety and depression, to fully understand the effects of the COVID-19 pandemic on mental health.
SANATIVE EFFECT OF MULTIHERBAL FORMULATION – AKSS16-LIV01 ON CCL4-INDUCED HEPATIC DYSFUNCTION IN MICE
Authors: DARBAR SOUMENDRA , SAHA SRIMOYEE , PRAMANIK KAUSIKISANKAR , CHATTOPADHYAY ATISKUMAR 
Published: January 2021

Objectives: Hepatic dysfunction is a critical public health problem affecting the global population, characterized by excessive deposition of extracellular matrix components due to increased matrix production and decreased matrix degradation. The present work was aimed to evaluate hepatoprotective effect of AKSS16-LIV01 a newly developed multiherbal formulation against carbon tetrachloride (CCl4)-induced liver dysfunction in Swiss albino mice to establish it as a bench to bedside formulation catering to the various facets of hepatic malfunction.
Methods: Thirty-six Swiss adult albino Wister mice divided into six groups. Group-I control untreated animals, Group-II received AKSS16-LIV01 (400 mg/kg), Group-III received CCl4 (1 ml/kg-bw), Group-IV received AKSS16-LIV01 (200 mg/kg) after 2 weeks CCl4 induction, Group-V received AKSS16-LIV01 (400 mg/kg) after 2 weeks CCl4 induction, and Group-VI received standard drug silymarin (100 mg/kg). At the end of the experimental period, all the animals were fasted overnight and blood was collected through retro-orbital plexus for preparation of serum and was analyzed for biochemical parameters, lipid profile, and total plasma protein. Liver tissue was collected for histological study.
Results: The combined plant extract including six Indian medicinal herbs and three medicinal spices (AKSS16-LIV01) showed significant hepatoprotective effect by controlling the various essential biochemical parameters in serum. Moreover, treatment with AKSS16-LIV01 raised the level of serum total protein, normalizes the serum biochemical and lipid profiles parameters. Pre-treatment with AKSS16-LIV01 in mice also restored the alteration of various liver parameters such as aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, gamma-glutamyl transferase, blood urea nitrogen, total bilirubin, and direct bilirubin on CCl4-induced liver damage. Gross liver morphology and normal histological examination of the liver also supported hepatic protection by AKSS16-LIV01.
Conclusion: Taken together, these results suggest that AKSS16-LIV01 may induce remarkable protective effects against hepatic injury induced by CCl4 treatment.
DRUG POLYMORPHISM IDENTIFICATION USING FOURIER TRANSFORM-RAMAN SPECTROSCOPY: A COMPARATIVE STUDY OF LAMIVUDINE AND FINASTERIDE DRUGS
Authors: RAO M CHANDRA SEKHARA , REDDY R CHENNA KRISHNA , SEKHAR KB CHANDRA , YV RAMI REDDY 
Published: January 2021

Objectives: Maintaining the quality of the pharmaceutical drug product during its shelf life is highly desirable. The crystalline form of the drug having the great thermodynamic stability is essential for the manufacturers in pharmaceutical industry in view of their profit and also for the safety of the customer. Many pharmaceutical drugs have the tendency to exhibit polymorphism which is unwanted for pharmaceutical companies, where they have experienced market shortages due to these unpredicted polymorphic and/or pseudomorphic changes. The property of a drug exhibiting more than one crystal form is considerably regarded as polymorphism and each of the crystalline form has its own physicochemical properties, namely, solubility, heat capacity, melting point, and sublimation point. To relieve this ultimate effect on the drug quality and stability, a prior detection of polymorphism in the final dosage form is highly recommended. Hence, many analytical techniques have been proposed for the detection of polymorphism in pharmaceutical drug products.
Methods: Fourier transform (FT)-Raman spectrometer is used for the investigation of drug polymorphism and the instrument is advanced with charge coupled device detectors, ease of sample preparation and handling, mitigation of sub-sampling problems using different geometric laser irradiance patterns and having different optical components of Raman spectrometers.
Results: In this work, we carefully studied the Raman spectral patterns for Lamivudine as well as Finasteride drug substances for the detection of polymorphism. Further, we have highlighted the advantages of FT-Raman spectroscopy over other polymorphism detection techniques. For example, Raman spectra showed invariably sharp, well resolved bands compare to IR spectra due to the minor contribution of overtone vibrations in Raman spectra, resulting in much less broadening and a better resolution of bands. Besides, Raman spectroscopy does not suffer from the sampling problems that are common in X-ray powder diffraction, where preferred orientation and specimen displacements are serious restrictions for the application of quantitative method.
Conclusion: Here, in this paper, we are presented and compared the experimental results regarding the detection of polymorphism in Lamivudine and Finasteride drugs using FT-Raman spectroscopy, to illustrate the advantages of the technique in the detection of polymorphism over other techniques.
Restorasi Ideologi Pancasila Dalam Pemiki Ahmad Syafi'i Ma'arif
Authors: Yusuf Nurbani 
Published: January 2021

Penelitian ini membahas mengenai restorasi pemikiran Ahmad Syafii Maarif selaku anggota dewan Pengarah Badan Pembinaan Ideologi Pancasila terhadap Pancasila sebagai ideologi. Pendekatan yang digunakan dalam penelitian ini adalah pendekatan kualitatif. Sedangkan metode penelitian adalah deskriptif. Adapun hasil dalam penelitian ini adalah Restorasi Ideologi Pancasila dalam pemikiran Anggota Dewan Pengarah Badan Pembinaan Ideologi Pancasila yakni Ahmad Syaf’I Ma’arif merupakan usaha berpikir kritis dalam mengejawantahkan dan mengembangkan ideologi Pancasila agar mampu bertahan dengan kondisi perubahan zaman. Pengejawantahan yang di lakukan oleh Ahmad Syaf’I Ma’arif merupakan suatu bentuk pemikiran yang sistematis, metodis dan valid dalam mengembangkan ideologi Pancasila agar dapat tetap relevan dengan kondisi dan tantangan zaman. Dengan tujuan agar ideologi Pancasila dapat terus membumi atau dapat di tarik kebumi sehingga Pancasila sebagai ideologi negara dapat benar-benar menjadi pedoman dalam kehidupan bermasyarakat, berbangsa, dan bernegara. Sehingga tujuan akhir yakni keadilan sosial bagi seluruh rakyat Indonesia dapat segera atau mengalami percepatan dalam laju gerak langkah negara ini.
Peran Organisasi Gerakan Mahasiswa Nasional Indonesia Dalam Mentransformasikan Nilai-Nilai Pancasila Di Universitas Muhammadiyah Malang
Authors: Wibowo Arif Prasetyo , Djuyandi Yusa , Agustino Leo 
Published: January 2021

Tujuan dalam penelitian ini adalah untuk mengetahui dan menganalisis peran Organisasi Gerakan Mahasiswa Nasional Indonesia di Universitas Muhammadiyah Malang dalam mentransformasikan nilai-nilai Pancasila kepada para kadernya. Metode yang digunakan dalam penelitian ini adalah deskriptif kualitatif. Dengan temuan penelitian peran organisasi Dewan Pimpinan Komisariat Gerakan Mahasiswa Nasional Indonesia Universitas Muhammadiyah Malang dalam mentrasformasikan nilai-nilai Pancasila dilakukan dengan bentuk Program Kerja disetiap periode kepengurusan organisasi yang dapat dilihat melalui lima indikator dalam teori peran, yakni aksi, patokan, penilaian, paparan, dan sanksi.
Educación a distancia: algunos desafíos teóricoprácticos
Authors: Bolaños Calvo Bolívar 
Published: January 2021

Este artículo trata de brindar al lector una contextualización o marco de referencia en el cual se está desarrollando la modalidad de educación a distancia. Por otro lado, pretende dar a conocer las ventajas o alcances y desventajas o aspectos que deben rechazarse de la modalidad educativa. Intenta rescatar la función o el papel preponderante de ésta como una opción válida para que muchas poblaciones tengan la oportunidad de ingresar en el concierto del proceso educativo para aumentar su calidad de vida y actuar en la sociedad más responsablemente. También plantea la trascendencia e importancia, así como la repercusión que ha tenido y tendrá el ingreso de la tecnología o las innovaciones tecnológicas, en el proceso de enseñanza-aprendizaje en dicha modalidad, la cual será un instrumento de la mediación pedagógica y no un fin como a veces se pretende. Por último, intenta rescatar enfoques modernos entre los que se encuentra una visión constructivista del aprendizaje como herramienta válida en el desarrollo de las habilidades y destrezas de los estudiantes.
A Case Study in Managing the Analytics “Iceberg”: Data Cleaning and Management using Alteryx
Authors: O'Brien Ann , Stone Dan N. 
Published: January 2021

ABSTRACT
This case introduces accounting students to data management using a “no code” approach. Many tools can be used for extract, transform, load (ETL) processes. Herein, we introduce ETL using Alteryx Designer, a market-leading tool for managing and manipulating data. In the case, students learn basic data cleaning and joining skills, explore key data management concepts including workflows and metadata, and learn how to create and document workflows in Alteryx. Undergraduate or graduate accounting students who have basic database knowledge (e.g., in an introduction to accounting systems class) and data processing skills will benefit from the case. Evidence from use suggests that the case is relevant, challenging, and useful for the goal of teaching introductory and intermediate-level ETL skills, using Alteryx. The case is easy to implement and an important resource for teaching data management and Alteryx Designer.
Surgical-orthodontic treatment for severe malocclusion in a patient with osteopetrosis and bilateral cleft lip and palate:
Authors: Kim Jin-Kyu , Kim Jun-Young , Jung Hwi-Dong , Jung Young-Soo 
Published: January 2021

ABSTRACT
Orthognathic surgery in patients with craniofacial osteopetrosis, a condition associated with osteoclast dysfunction, is usually avoided because of the risk of osteomyelitis. A 19-year-old woman presented with the chief complaint of severe malocclusion and anterior crossbite. After radiographic evaluation, craniofacial osteopetrosis was diagnosed. Surgical-orthodontic treatment was performed after meticulous history taking and verification of normal bone turnover using bone-metabolism markers for endocrine evaluation. Favorable esthetic and functional outcomes were achieved.
Applications of Mathematics Charged Islamic Values by Using Macromedia Flash and Camtasia
Authors: Durri Agus Ahmad , Raharjo Hendri , Muchyidin Arif 
Published: January 2021

Some factors of low interresting of Mathematic learning material for student on Junior High School grade (SMP/MTs) are design of learning material that is less animation and the difficuties of use the learning material. Therefore, the use of learning material should be inovated for increasing the learners’ interrest, to make them easy understanding the subject that has been learnt, and still capable to increase reigion value in their ownselves. One form of this effort is to create learning material in the form of flash mathematics with consits Islamic value. Flash application is an application that can be developed in accordance animatif developer creativity. The purpose of the research is the developing of learning material in the electric learning form that consists Islamic value in Transformation subject. The method of research is research and development, and the design of the research is using the steps of ADDIE model, there are analysis, design, development, implemetation, and evaluation. Data collection techniques included interviews and observations with research instruments are questionnaires, observation sheets and tests. Further analysis of the data conducted by researchers consists of qualitative and quantitative analysis to determine the feasibility and effectiveness of the teaching materials developed. The results of the expert evaluation consisting of a material expert and a media expert, shows that the average velue obtained from every aspects: content quality and purpose,instructional quality of learning material, aspects of the charge Islamic value, and the technique quality was 4.37 that very good category. The results of the assessment by the teachers of Junior High School grade (MTs) Nurul Huda Munjul which consist of two Mathematics teacher and a teacher of Information and Communication Technology (ICT), shows that the average velue of each aspect was 4.46 with very good category. Than the student quationnaire responses result data obtained by the average velue of each aspects: the quality of learning and instructional, technical aspects of the display, and payload integrition aspects of Islamic value in learning material, namely 3.98, with good categories. The data test scores of student learning outcomes gained an average of 82.34 > KKM (75) with the classical completeness of 89.19% > 85%. The conclusion showed that the quality of Mathematic learning materials charged Islamic velues are developed with macromedia flash and catamsia aplications is feasible and effective to be used in the learning process.
Pembuatan Perangkat Lunak Sistem Informasi Penjualan Tunai Berbasis WEB Di PT. Propan Raya Cirebon
Authors: Sokibi Petrus 
Published: January 2021

he rapidly Technology Progress, especially in Computer, is very useful to the human in doing their job. Nowadays, the global era, every business needs a tool, Computer, to support their activities, especially to process data and information. In this research, the writer presents the topic titled: ”The Building of Software for Information System in Cash Selling by using WEB at PT. Propan Raya Cirebon” as the development of the existing system from manual to the computerized system. This system is built by using PHP language program and MySql as the database storage. In this application, the user can process the selling transaction, input goods, and consumer data. When the transaction is being processed, the system will process the updating of stock in the database automatically, meanwhile, the user can determine the stocking in the store directly. Based on the research done on the trial, the Information system of cash selling has been successfully processed.
Assessment of circulating tumor cells in peripheral blood using flow cytometry in patients with surgery for colorectal cancer – review
Authors: Muşină Ana-Maria , Huţanu Ionuţ , Zlei Mihaela , Ştefan Mădălina , Mentel Mihaela , Aniţei Maria-Gabriela , Filip Bogdan , Scripcariu Dragoş Viorel , Gavrilescu Mihaela-Mădălina , Panuţa Andrian , Buna-Arvinte Mihaela , Radu Iulian , Scripcariu Viorel 
Published: January 2021

Abstract

Introduction: Colorectal cancer (CRC) is the third most common neoplasia in the world. Circulating tumor cells (CTC) have a prognostic value and can be useful in monitoring solid neoplasia. Only one method for CTC identification has received the approval and this is the CellSearch® system based on the immunomagnetic separation. Multiple markers are used in CTC identification, as epithelial markers and cytokeratines. CTC identification in peripheral blood is associated with a worse prognostic and reduced free survival in CRC.

Material and methods: We performed a systematic search in PubMed database for articles that reports the circulating tumor cells in CRC until July 2019. We selected studies in English and French and the main words used for search were ‘circulating tumor cells’, ‘colorectal cancer’, ‘colon cancer’, ‘rectal cancer’, ‘flow cytometry’, ‘peripheral blood’. We included studies with more than 10 patients, where samples were collected from the blood in relation with surgery and flow cytometry was used as analyzing technique.

Results: We included 7 studies in final analysis, that showed in flow cytometry analysis a cut-off value of CTC that can vary from 2-4 CTC/ 7.5 ml peripheral blood with a sensitivity of 50.8% and specificity of 95%. Patients with positive CTC were associated with higher T stage and positive lymph nodes, with a worse overall survival (OS) and disease free survival (DFS) comparing with negative patients.

Conclusion: CTC are considered to be a prognostic factor who needs more validation studies in order to be included in the clinical practice.
POTENSI PEMANFAATAN LUBANG RESAPAN BIOPORI DI KELURAHAN KOTA BAMBU SELATAN, PALMERAH, JAKARTA BARAT
Authors: Purwaningrum Pramiati , Winarni Winarni , Yulinawati Hernani , Tazkiaturrizki Tazkiaturrizki 
Published: January 2021

Biopore Infiltration Hole (LRB) is an alternative and simple technology for rainwater infiltration that can be useful as a processor for organic waste from households and can be applied in narrow urban residential areas such as in Kota Bambu Selatan (KBS) Sub-district. LRB technology in general is to reduce water inundation, increase groundwater reserves, and reduce the volume of organic waste. Therefore, the Community Service Program of the Environmental Engineering Study Program has the aim of providing counseling and training to PPSU officers (Public Facilities and Infrastructure Handling Workers) of KBS Sub-district in implementing LRB in accordance with technical requirements without impacting groundwater pollution. The method used was to provide LRB educational materials aimed at the community, especially PPSU officers through direct explanations, educational posters and brochures. The current condition is that KBS Sub-district already has LRB at several points in 2017, however it got some technical problems such as pipe size is too small, namely 7.5 cm (minimum pipe diameter requirement is 10 cm); there is dredging activity, there is no top cover so that small animals often enter, and in some locations there is often stagnant water.