bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cultivo de Kalanchoe blossfeldiana em diferentes substratos contendo resíduos de erva-mate
Authors: Monteiro Daniela Machado , Girardi Leonita Beatriz , Menegaes Janine Farias , Steffens Cristian José , Pereira Jackson Vinícius Rodrigues , Reinehr Tarik Ian 
Published: May 2021

Em busca de uma agricultura de baixo impacto ambiental, o objetivo com este trabalho foi avaliar o cultivo de Kalanchoe blossfeldiana Poelln. (calandivas) cultivar Amora, submetidas a diferentes substratos contendo na sua composição resíduos de erva-mate. O experimento foi conduzido em delineamento inteiramente casualizado, com cinco tratamentos compostos pelas diferentes misturas do substrato comercial e o resíduo de erva-mate compostada, obtendo as composições: S1: 100% substrato comercial (SC); S2: 50% SC + 50% resíduo de erva-mate (REM); S3: 25% SC + 75% REM; S4: 75% SC + 25% REM e S5: 100% REM, com cinco repetições, cada unidade experimental foi constituída por um vaso de planta. Analisou-se as variáveis quanto à altura das plantas e comprimento radicular, diâmetro das inflorescências, número de flores e folhas e massa fresca radicular. Observou-se que o desenvolvimento das plantas de calandivas foi similar com as diferentes combinações contendo o substrato comercial e o resíduo de erva-mate. No entanto, o substrato contendo apenas com os resíduos de erva-mate não é recomendado para esse cultivo. Por fim, recomenda-se para o cultivo de calandivas em vasos o uso do substrato composto de 50% substrato comercial + 50% resíduo de erva-mate (S2).
Presence of Extra-Criteria Antiphospholipid Antibodies Is an Independent Risk Factor for Ischemic Stroke
Authors: Naranjo Laura , Ostos Fernando , Gil-Etayo Francisco Javier , Hernández-Gallego Jesús , Cabrera-Marante Óscar , Pleguezuelo Daniel Enrique , Díaz-Simón Raquel , Cerro Mercedes , Lora David , Martínez-Salio Antonio , Serrano Antonio 
Published: May 2021

Background: Ischemic stroke is the most common and severe arterial thrombotic event in Antiphospholipid syndrome (APS). APS is an autoimmune disease characterized by the presence of thrombosis and antiphospholipid antibodies (aPL), which provide a pro-coagulant state. The aPL included in the classification criteria are lupus anticoagulant, anti-cardiolipin (aCL) and anti-β2-glycoprotein-I antibodies (aB2GPI) of IgG and IgM isotypes. Extra-criteria aPL, especially IgA aB2GPI and IgG/IgM anti-phosphatidylserine/prothrombin antibodies (aPS/PT), have been strongly associated with thrombosis. However, their role in the general population suffering from stroke is unknown. We aim (1) to evaluate the aPL prevalence in ischemic stroke patients, (2) to determine the role of aPL as a risk factor for stroke, and (3) to create an easy-to-use tool to stratify the risk of ischemic stroke occurrence considering the presence of aPL and other risk factors.Materials and Methods: A cohort of 245 consecutive ischemic stroke patients was evaluated in the first 24 h after the acute event for the presence of classic aPL, extra-criteria aPL (IgA aB2GPI, IgG, and IgM aPS/PT) and conventional cardiovascular risk factors. These patients were followed-up for 2-years. A group of 121 healthy volunteers of the same age range and representative of the general population was used as reference population. The study was approved by the Ethics Committee for Clinical Research (Reference numbers CEIC-14/354 and CEIC-18/182).Results: The overall aPL prevalence in stroke patients was 28% and IgA aB2GPI were the most prevalent (20%). In the multivariant analysis, the presence of IgA aB2GPI (OR 2.40, 95% CI: 1.03–5.53), dyslipidemia (OR 1.70, 95% CI: 1.01–2.84), arterial hypertension (OR 1.82, 95% CI: 1.03–3.22), atrial fibrillation (OR 4.31, 95% CI: 1.90–9.78), and active smoking (OR 3.47, 95% CI: 1.72–6.99) were identified as independent risk factors for ischemic stroke. A risk stratification tool for stroke was created based on these factors (AUC: 0.75).Conclusions: IgA aB2GPI are an important independent risk factor for ischemic stroke. Evaluation of aPL (including extra-criteria) in cardiovascular risk factor assessment for stroke can potentially increase the identification of patients at risk of thrombotic event, facilitating a decision on preventive treatments.
Implementation of the PIERS on the Move mHealth Application From the Perspective of Community Health Workers and Nurses in Rural Mozambique
Authors: Boene Helena , Valá Anifa , Kinshella Mai-Lei Woo , La Michelle , Sharma Sumedha , Vidler Marianne , Magee Laura A. , von Dadelszen Peter , Sevene Esperança , Munguambe Khátia , Payne Beth A. ,   the CLIP Mozambique Working Group
Published: May 2021

Background:mHealth is increasingly regarded as having the potential to support service delivery by health workers in low-resource settings. PIERS on the Move (POM) is a mobile health application developed to support community health workers identification and management of women at risk of adverse outcomes from pre-eclampsia. The objective of this study was to evaluate the impact of using POM in Mozambique on community health care workers' knowledge and self-efficacy related to caring for women with pre-eclampsia, and their perception of usefulness of the tool to inform implementation.Method: An evaluation was conducted for health care workers in the Mozambique Community Level Intervention for Pre-eclampsia (CLIP) cluster randomized trial from 2014 to 2016 in Maputo and Gaza provinces (NCT01911494). A structured survey was designed using themes from the Technology Acceptance Model, which describes the likelihood of adopting the technology based on perceived usefulness and perceived ease of use. Surveys were conducted in Portuguese and translated verbatim to English for analysis. Preliminary analysis of open-ended responses was conducted to develop a coding framework for full qualitative analysis, which was completed using NVivo12 (QSR International, Melbourne, Australia).Results: Overall, 118 community health workers (44 intervention; 74 control) and 55 nurses (23 intervention; 32 control) were surveyed regarding their experiences. Many community health workers found the POM app easy to use (80%; 35/44), useful in guiding their activities (68%; 30/44) and pregnant women received their counseling more seriously because of the POM app (75%; 33/44). Almost a third CHWs reported some challenges using the POM app (30%; 13/44), including battery depletion after a full day's activity. Community health workers reported increases in knowledge about pre-eclampsia and other pregnancy complications and increases in confidence, comfort and capacity to advise women on health conditions and deliver services. Nurses recognized the increased capacity of community health workers and were more confident in their clinical and technological skills to identify women at risk of obstetric complications.Conclusions: Many of the community health workers reported that POM improved knowledge, self-efficacy and strengthened relationships with the communities they serve and local nurses. This helped to strengthen the link between community and health facility. However, findings highlight the need to consider program and systematic challenges to implementation.
IL-14α as a Putative Biomarker for Stratification of Dry Eye in Primary Sjögren’s Syndrome
Authors: Liang Yichen , Xian Zhenhua , Fu Dehua , Liu Shuang , Yao Yang , Jin Yuebo , Gao Chun , Shen Long , Shi Guixiu , He Jing 
Published: May 2021

BackgroundDry eye is often the first presenting manifestation of primary Sjögren’s syndrome (pSS). Because of the high prevalence of dry eye disease in normal population, ophthalmologists urgently need a non-invasive and reliable screening test to diagnose dry eye associated SS patients, other than ocular symptoms and signs. Currently, there is no single test available. The correlation of serum IL-14α with pSS has been found in pSS mouse model.PurposeTo evaluate whether IL-14α can serve as a biomarker to stratify dry eye in primary Sjögren’s syndrome and its correlation to BAFF in a cohort of patients with non-SS dry eye (NSDE), pSS with dry eye disease, rheumatoid arthritis (RA), and healthy controls (HC).MethodsRetrospective study based on serum levels of IL-14α (defined by Western Blot) and BAFF (measured by ELISA) were evaluated among pSS with dry eye disease, NSDE, RA, and HC groups. Serum levels of SS related autoantibodies (Ro, La, SP1, PSP, and CA6) were also measured by ELISA.ResultsOne hundred and eighty patients were included for the current study, patients were separated into four groups as defined by pSS (n=65), NSDE (n=20), RA (n=50) and HC (n=45). The level of serum IL-14α in pSS was significantly higher compared to NSDE, RA, and HC (p=0.0011, p=0.0052 and p&lt;0.0001, respectively). The levels of serum BAFF in pSS was significantly higher than in NSDE and HC (p=0.0148 and p&lt;0.0001, respectively, whereas the levels of serum BAFF in RA was only significantly higher than in HC (p=0.001), but the level of BAFF was no significant difference between pSS and RA. In pSS, there was a decrease in the serum levels of IL-14α associated with a longer duration of the disease. Also, there was a correlation between the serum levels of IL-14α and SS related autoantibodies such as anti-SSA/Ro and anti-SSB/La in pSS patients.ConclusionsThis is the first paper to report both IL-14α and BAFF could serve as a critical cytokine biomarker for the stratification of dry eye in primary Sjögren’s syndrome. This may help ophthalmologists to develop non-invasive metrics for the diagnosis of dry eye associated pSS.
Efficacy and Safety of Radiofrequency Ablation for Breast Cancer Smaller Than 2 cm: A Systematic Review and Meta-Analysis
Authors: Xia Lin-Yu , Hu Qing-Lin , Xu Wei-Yun 
Published: May 2021

BackgroundTo evaluate the efficacy and safety of radiofrequency ablation (RFA) of breast cancer smaller than 2 cm.MethodsA systematic search was conducted in the PubMed and EMBASE databases to identify published studies investigating the efficacy and safety of RFA for breast cancer smaller than 2 cm. The main outcomes were technical success rate of the ablation, complete ablation rate, complications and local recurrence. Secondary considerations were mode of anesthesia, pain tolerance, mean ablation time and surgical excision after ablation.ResultsSeventeen studies involving 399 patients and 401 lesions met the inclusion criteria. Nearly 99%(95%CI=0.98-1.00) of lesions achieved good technical success rate.Notably, 83.88% of the patients received RFA under general anesthesia (333/397) whereas 15.87% received RFA under local anesthesia (63/397). Of the 63, 98.41% tolerated the pain associated with the procedure. Majority of patients (65.74%, 261/397) underwent surgical excision of the tumor after ablation whereas in a few patients (34.26%, 136/397), the tumor tissue was retained in the breast after ablation. Complete ablation was achieved in 96% of patients for a mean time of 15.8 minutes (95%CI=0.93-0.99). Overall, only 2% (95%CI=0.01-0.04) of the individuals developed complications. Skin burns (2.02%, 8/397) were the most common complications. There was no local recurrence after a median follow-up of 27.29 months, whether or not they underwent surgical resection following RFA.ConclusionThe results show that RFA for breast cancer smaller than 2 cm is safe and effective. However, prospective studies are needed to validate this conclusion.
ANALISIS FUNGSI PRODUKSI USAHA TERNAK SAPI DI KECAMATAN TOMPASO BARAT KABUPATEN MINAHASA
Authors: Thamrin Aprilia M , Elly Femi H , Santa Nansi M , Manese Merry A.V 
Published: May 2021

PRODUCTION FUNCTION ANALYSIS OF CATTLE FARMING IN WEST TOMPASO DISTRICT REGENCY OF MINAHASA.Farmers in West Tompaso district cultivatedBeef cattle traditionally and not as main farming.The government in this case also encourages farmers to increase production. The problem is whether the production factor used affects the production of beef cattle. The research aims to determine the factors affecting cattle production. The data collected is primary data and secondary data. Sampling uses the Cluster Random Sampling method. The analysis of the data used is multiple regression with econometrics approaches and software using SAS program 9.4. The results showed that the respondents ' lifespan ranged from 30-65 years to categorized productive age. Based on the results of the study can be concluded that together the factors of land production, labor and feed are real effect on the production of beef cattle. Land production and feed factors that have real effect on the production of beef cattle.Keywords: Land, labor, feed, beef cattle
PENGARUH JARAK TANAM indigofera zollingeriana TERHADAP KAPASITAS TAMPUNG POTENSIAL TERNAK SAPI DI AREAL PERTANAMAN KELAPA
Authors: Ering Verlando J. , Telleng Malcky M. , Rumambi Agnitje , Sumolang Constantyn I.J. 
Published: May 2021

THE EFFECT OF PLANTING SPACING indigofera zollingeriana ON POTENTIAL CARRYING CAPACITY OF BEEF CATTLE IN COCONUT PLANTATION. This study seeks to know the influence of the distance cropping indigofera zollingeriana faith in capacity of the potential capacity cattle in the area coconut plantations with distance different cropping. This research using complete random design (CRD) with 3 treatment consisting of j1: distance cropping 1,0 m x 0,5 m , j2: distance cropping 1,0 m x 1,0 m, and j3: distance cropping 1,0 m x 1,5 m, each treatment consisted of 6 test. Variable measured was fresh production, the production of dry ingredients and capacity capacity. The analysis showed that the treatment plant exert distance different very real (P<0,01 ) of fresh production, the production of dry ingredients and capacity potential capacity test BNJ showed that the distance cropping 1,0 m x 0,5 m give fresh production, the production of dry ingredients and capacity different capacity very real (P<0,01 ) higher than the plant 1,0 m x 1,0 m and distance cropping 1,0 m x 1,5 m . It can be concluded that the distance plant 1,0 m x 0,5 m produce fresh production, the production of dry substances and capacity of the highest potential capacity .Key words: Indigofera zollingeriana, planting space, Potential carrying capacity
PENAMPILAN REPRODUKSI TERNAK SAPI POTONG YANG DI INSEMINASI BUATAN DI KECAMATAN TOMBATU UTARA DAN KECAMATAN RATAHAN
Authors: Sawel Ariny Irma , Lomboan Agustinus , Paath Jantje , Manopo Jouke 
Published: May 2021

REPRODUCTIVE PERFORMANCE BEEF CATTLE OF ARTIFICIAL INSEMINATION IN THE DISTRICT OF NORTH TOMBATU AND SUB DISTRICT OF RATAHAN. The porpose of this study to know appearance of reproduction beef cattle artificial insemination in the northern Tombatu District and the Sub District of Ratahan in the Southeast Minahasa Regency. Research the everage valve standard deviation and coefficient of diversity. Based on research results that service preconception 1.25-1.30, conception rate 70-75%, calving interval 366.4-377.55 and length of pregnancy 279.25-281.1 day. It can be colcluded that the reproductive performance of artificial insemination beef cattle in North Tombatu and Ratahan Districts already quite good. Keywords: Reproduction, beef cattle, artificial insemination
GENERA NYAMUK (CULICIDAE) DALAM KANDANG SEBAGAI VEKTOR PENYAKIT JAPANESE ENCEPHALITIS PADA TERNAK BABI DI DESA TOLOK KECAMATAN TOMPASO KABUPATEN MINAHASA
Authors: Lengkey Dave R. , Podung A.J. , Nangoy M.J. , Lapian M. Th. 
Published: May 2021

MOSQUITOS GENERA (CULICIDAE) IN CAGE AS A VECTOR OF JAPANESE ENCEPHALITIS IN PIGS IN THE TOLOK VILLAGE, TOMPASO DISTRICT, MINAHASA DISTRICT This study aims to determine the diversity and density of the population and the time of mosquito activity (Culicidae) in the pig pen. This reserch was carried out in the Tolok Village, Tompaso District, Minahasa Regency for 2 (two) months at 2 (two) cage locations namely cage I (distance I cage withe house less than 10 m) and enclosure II (more than 50 m). This research uses the observation method by collecting mosquito samples every 2 (two) hours on the light trap placed in each cage. Samples were collected from 18.00-06.00, at each location replicated 3 (three) times with an invoice of two weeks, the samples collected are identified and counted. The results showed diversity of cage mosquitoes I and II each found 3 genera namely Culex, Anopheles, and Armigeres. Population density of cage I was found 128 individual mosquitoes consisting of Culex 104 tails, Anopheles 20 tails, and Armigeres 4. Cage II found 46 mosquitos individuals consisting of Culex 40, Anopheles 5, Armigeres 1. Hours 22.00-24.00 is the highest time of mosquito activity obtained from the highest number of mosquito catches, which were 48 in cage I and 18 in cage II. Based on the results and discussions, it was concluded that mosquito diversity in the Tolok Village 3 genus Culex, Anopheles, and Armigeres while the highest mosquito population density was at the cage location closest to the breeder house and its activity was highest at 22.00-24.00. Keyword: Mosquito, pig livestock, activity, density, diversity
POLA PEMASARAN SAPI POTONG JENIS PERANAKAN ONGOLE DI PASAR BLANTIK KAWANGKOAN (STUDI KASUS)
Authors: Weydekamp Jurian , Lumi T D.F , Endoh E K.M , Oroh F N.S 
Published: May 2021

MARKETING PATTERN OF ONGOLE CROSSBRED BEEF CATTLE IN THE KAWANGKOAN “BLANTIK” MARKET (CASE STUDY). This study was done to identify the marketing pattern of beef cattle and factors causing the price difference at kawangkoan “blantik” market. The sample was determined using method of purposive sampling techniques and involving respondent of 10 household farmers. The criteria of respondents were as follows: 1). They had knowledge of “blantik” market marketing activities. 2). They were active in any marketing activity 3). They had the experiences in the transaction of beef cattle in the “blantik” market place. Data collections method used were conducted by surveys and interviews. A sort of descriptive set data analysis was examined the cases occurred in the field and the results of previous studies.The exterior assessment was factor mostly affecting different prices in the “blantik” market of Kawangkoan. Key word : Marketing pattern, “blantik” market, beef cattle.
PENGARUH FREKUENSI PEMUTARAN DAN POSISI TELUR PADA KEBERHASILAN PENETASAN TELUR AYAM KAMPUNG (Gallus gallus Domesticus)
Authors: Eoudia Jecqueline C. M. , Lambey Lucia J. , Saerang Josephine L. P. , Nangoy Fredy J. 
Published: May 2021

EFFECT OF TURNING FREQUENCY AND EGG POSITION ON HATCHABILITY OF CHICKEN EGGS (Gallus gallus Domesticus). This study aimed to determine effect of turning frequency and egg position on the hatching ability of chicken eggs. Study was conducted using 162 eggs of local hens inserted into hatching machine withcapacity of 300 eggs and implemented for 24 days. The experimental design of the completely factorial randomized design was applied consisting of 9 treatments and 3 replications. The two treatment factors were turning frequency consisted of 2 times a day, 3 times a day, 4 times a day, and egg position of 300, 600, and 900. The results of the analysis show that the effect of the turning frequency did not show a significant effect (P>0.05) on hatchability. However, egg position had a significant effect (P<0.5) on hatchability. There was no interaction between turning frequency and egg position againt hatchability and mortality. The conclusion of this research was the turning frequency of 2 times a day with egg slope position of 300 produced high hatchability and low level of mortality. Keywords : Egg turning frequency and position, hatchability, local hen.
POLA PENGELUARAN KONSUMSI RUMAHTANGGA TANI PENERIMA BANTUAN MODAL PRODUKSI TERNAK SAPI DI KECAMATAN TOMPASO BARAT KABUPATEN MINAHASA
Authors: Tangkere Christian , Umboh S J.K , Manese M A.V , Santa N M 
Published: May 2021

THE PATTERN OF HOUSEHOLD FARMERS CONSUMPTION EXPENDITURE OF BENEFICIARIES OF CAPITAL ASSISTANCE FOR CATTLE PRODUCTION IN THE WESTERN TOMPASO DISTRICT OF MINAHASA REGENCY. Household farmers are one of the economic units that have a relationship with production and consumption decisions. Assistance of livestock production capital obtained by household farmers allocated its use in the context of household consumption to maximize the utility or satisfaction of the household. This research aims to analyze the pattern of consumption expenditure on farmers households as a recipient of production capital assistance for livestock. The study used descriptive and quantitative analysis. The respondent of this research which is household farmer’s as one of the recipients of capital assistance that has been selling cows. Patern of household consumption expenditure by farmers as beneficiaries of capital assistance in the district of West Tompaso divided into: Food and Non-food consumption. Expenditure of food consumption differentiated two types which are expenditure of food consumption purchased and not purchased. The results showed that out of all three allocation of consumption expenditure is known that the allocation of food consumption expenditure of household farmers is divided in to the first; the largest purchased for fish production is 28.69 percent, second; the value expenditure of food consumption not purchased in food seasonings (29.94%), and the last one is the allocation of non-food consumption expenditure were on clothing, footwear, and headgear (27.83%.) Keywords :Expenditure, consumption, households
Experience of Localizing Value Chains in the Automotive Industry
Authors: Shirinov A. Sh. o. 
Published: May 2021

Aim. The presented study aims to illustrate that by making use of industrial localization tools, the one business space (OBS) system solves the problem of replacing global value chains with local ones, leading to positive innovation-oriented structural sectoral transformations and the development of the economy’s export-oriented potential.Tasks. The authors examine the types of localization and the strategy of an automotive company for the formation and operation of regional sectoral OBS systems over time (2012–2019) through the example of the petrochemical and metalworking industries in the Republic of Tatarstan, showing the possibility of transforming industrial localization into import substitution.Methods. This study uses modern achievements of the theory of knowledge, innovation-driven development, methods of systematization and analysis, empirical research, including the collection, examination, and generalization of practical material, forecasting, analysis of the works of Russian and foreign scientists in the field of technological and non-technological activities, principles of change management.Results. By using industrial localization tools for the formation of multiple value chains in the host region within the framework of a partnership, it is possible to create an industry-wide vertically integrated management system for the innovation-driven development of automotive components production at the regional level. Horizontal integration into the social, scientific, and educational spheres of regions is a mandatory aspect for the development of such systems, which leads, among other things, to the development of scientific potential while also improving the quality of human capital. Within the framework of OBS, regional value chains are formed — from the extraction of raw materials to the final assembly of the car — with a total average annual turnover of 25 billion rubles. A significant number of jobs are created, as well as new automotive components and materials with unique properties for the Russian industry. This facilitates the production of Russian analogues in the interests of other OEMs and consumers, as well as the transformation of industrial localization into import substitution. In addition, products of localization are beginning to replace their analogues in the global supply chains of automotive components, thereby developing the export-oriented component of the regional economy.Conclusions. In certain cases, industrial localization in OBS systems is transformed into import substitution, significantly increasing the efficiency of industrialization in the region and the country as a whole.