bluuebunny/crossref_metadata_2025_split huggingface dataset:
10-YEAR ANNIVERSARY OF THE SLEEP HEALTH PERSPECTIVE: INSIGHTS FOR AGING RESEARCHERS
Authors: Lee Soomi , Kaufmann Christopher , Buysse Daniel 
Published: January 2025

Abstract
In 2014, Dr. Buysse published a seminal paper, titled “Sleep health: can we define it? Does it matter?” which proposed that sleep health extends beyond the absence of sleep disorders. He advocated for a preventive approach where individuals must address multiple aspects of sleep to support optimal functioning and health. The concept of sleep health initiated a paradigm shift, prompting researchers to consider multiple sleep variables, not solely sleep duration, to gain a holistic understanding of individuals’ sleep patterns. As we approach the 10-year anniversary of the sleep health perspective, this symposium brings together four esteemed speakers to discuss methodological approaches and empirical findings related to the link between sleep health and cardiovascular and cognitive aging outcomes, as well as social disparities in sleep health. Dr. Wallace will outline methodological challenges in assessing sleep health and clarify the advantages and disadvantages of various methods. Dr. Buxton will present a multi-dimensional sleep health model assessed by actigraphy and its association with cardiometabolic and cognitive aging outcomes in two US midlife and older adult samples. Dr. Knutson will share findings from US and Brazil population-based studies with subjective and objective dimensions of sleep health, including gender and racial differences in sleep health and cardiovascular risks. Dr. Stone will integrate epidemiology and clinical evidence to explore the link between sleep health, cognitive decline, and the onset of dementia. Finally, the discussant, Dr. Buysse, will synthesize the significance of findings, and identify opportunities for extending the sleep health perspective to future research and opportunities. Sleep, Circadian Rhythms and Aging Interest Group Sponsored Symposium
AGING AND CLIMATE CHANGE: FROM VULNERABILITY TO ACTION
Authors: Pillemer Karl 
Published: January 2025

Abstract
Despite the vulnerability of older people to climate change effects, as well as their potential to be part of climate change solutions, research has been limited. This multidisciplinary symposium responds to urgent calls for translational research on climate change as a critical pathway to reduce physical and mental health risks to older persons, brought about by climate-related hazards such as extreme temperature events, climate-related disasters, decreased air and water quality, forced migration, and vector-borne illnesses. Beyond vulnerability, panelists present research on older people’s actions to prevent and mitigate climate change. Two presentations provide new empirical findings on climate hazards. Bordes and Cherry examine how climate-related disasters affect health, using data from Hurricane Ida to examine differential effects on older and younger people. Koszalinski et al. examine effects of another climate-related hazard: harmful algae blooms, based on a longitudinal study of older adults in South Florida, demonstrating how such events can create harm from otherwise beneficial activities like outdoor nature activities. Two presenters focus on action taken by older people. Nikitin et al. address the intersection of the environment and attitudes toward aging, finding that nature contact is of special benefit to older persons. Liu and Pillemer examine intergenerational motivations for climate change activism among older people. Thiamwong’s presentation moves to community climate resilience strategies, presenting findings on community adaptation adapting to rising temperatures, with a focus on low-income older adults who are at special risk in extreme heat events.
CLIMATE-CREATIVE COMMUNITIES TO PROMOTE PHYSICAL ACTIVITY AND HEALTH EQUITY IN LOW-INCOME SETTINGS
Authors: Thiamwong Ladda , Kim Dahee , Xie Rui , Emrich Christopher , Zhong YunYing , Crook Jennifer , Hawthorne Timothy 
Published: January 2025

Abstract
Extreme heat is one of the most fatal weather hazards, and limited data suggest that low-income older adults (LOAs) who are exposed to extreme heat are less likely to participate in physical activity (PA). To develop climate-creative communities, we conducted onsite survey interviews with LOAs (n=41) and a focus group with community-based organizations (CBOs) (n=21). LOAs tended to have less frequent moderate to vigorous PA and had higher numbers of falls in summer compared to fall; 71% felt uncomfortable with extreme heat, and 69% rated their thermal sensation as slightly warm to very hot on extreme heat days. Regarding self-management on hot days, 89% drank water, 13% drank juice/favored beverage, 2% drank alcohol, 29% stayed inside, and 22% reduced PA. More than 50% stated heat or hot weather impacted their sleep, food consumption, and hydration; 32% reported heat impacted social connections, and 47% had no access to community resources (CR). The top five barriers to accessing CR were health issues (20%), don’t have time (11%), transportation from home to CR (9%), lack of interest (8.9%), and lack of knowledge and information about the services (6.7%). A focus group with CBOs (n= 21) agreed that there is currently scarce communication/coordination of relevant CR, and multilateral efforts are urgently needed to co-create community-based, culturally appropriate communication and outreach programs to encourage LOAs’ participation in PA, engage them in discussions about heat-health issues and provide them with access to shared CR to support their built community’s resilience in adapting to rising temperatures.
AGING REPROGRAMMED
Authors: Jasper Heinrich 
Published: January 2025

Abstract
Epigenetic reprogramming of differentiated cells into stem-like or plastic cells is a feature of regenerative processes in many tissues. This process can be leveraged to induce full pluripotency, which essentially represents a fully rejuvenated state of the epigenome. Evidence is now accumulating that partial in vivo epigenetic reprogramming, where reprogramming to pluripotency is initiated but not completed, can alleviate age-related dysfunction in tissue repair, and even extend lifespan. In a wide range of disease models, reprogramming has been shown to improve outcomes and promote tissue repair. This symposium will explore fundamental cellular mechanisms of partial reprogramming, the tissue consequences of in vivo reprogramming, and discuss the potential therapeutic impact of reprogramming on age-related diseases.
PARTIAL REPROGRAMMING REVERSES FEATURES OF AGING IN HUMAN T LYMPHOCYTES
Authors: Kimmel Jacob 
Published: January 2025

Abstract
Youthful gene expression and function can be restored in old cells by brief activation of transcription factors (TFs), a process known as partial reprogramming. Partial reprogramming holds promise as a therapeutic approach, but current methods have only employed a small set of pluripotency TFs that also reprogram cell identity in undesirable ways. It remains unknown if other TFs might be able to reprogram cell age, how long these effects last, and how often TFs act in concert to promote youthful phenotypes. To address these questions, we developed a screening technology called Partial-seq to measure the effect of partial reprogramming on gene expression across thousands of TF sets at once. We used Partial-seq to screen &gt;4000 TF sets in aged human T cells, a keystone cell type of the immune system that declines in function with age. We discovered that many TFs beyond pluripotency factors restored youthful gene expression and cell states, without abolishing T cell identity. TF combinations were more likely than individual factors to reverse cell age, and many of these effects persisted after TF activation ceased. Our results suggest that the phenotypic age of human T cells can be durably reversed by partial reprogramming with diverse TFs. The diversity of TF sets discovered in our screens suggests that reprogramming cell age might be accomplished without perturbing cell identity.
AN ASSET-BASED APPROACH TO INCREASE ENGAGEMENT OF OLDER AFRICAN AMERICANS IN HEALTH RESEARCH
Authors: Gaillard Trudy , Vaccaro Joan , Neff Donna , Padovano Cynthia Morton , Webb Fern 
Published: January 2025

Abstract
Asset-based approach to community engagement research aims to identify community strengths that improve health and health equity. The objective of the current study was to identify strategies expressed by older African Americans (OAA) to increase their engagement in health research. The following report was part of a larger study exploring the impact of intergenerational influence and perceptions regarding willingness to participate in health research among ethnically diverse OAA. Participants were recruited from North, Central, and South Florida using various community engagement strategies. Listening sessions were conducted in dyads; older adult (≥65 years) and a trusted family member/friend (25-64 years). The following results are from OAA (≥65 years). All transcripts were recorded and transcribed verbatim. NVivo software© was used for data management and analysis. There was a total of 14 listening sessions (N= 66). In general, most OAA consulted younger trusted family/friends about health concerns before deciding to participate in research. Key findings concerned, the researcher, goals of the research, and with whom and how information would be shared. Community assets identified that researchers should engage the community by: partnering with local primary care providers (both physicians and nurse practitioners); schools (intergenerational engagement); community liaisons “people who look like me”; and local trusted elected officials. Our results indicate that there are multiple community-based assets that can be used to engage Older African Americans in health research. An asset-based approach with community members identified encouraging suggestions that can be integrated into the design of health research for this population.
CLOSING THE EQUITY GAP: DEMENTIA RESEARCH WITH INDIGENOUS POPULATIONS
Authors: Lewis Jordan , Jacklin Kristen , Lewis Jordan 
Published: January 2025

Abstract
This symposium highlights community-based work focusing on Alzheimer’s disease and related dementias (ADRD) conducted with Indigenous populations across the United States and Canada. We describe not only outcomes and findings of these various projects but also the essential research processes necessary for creating relationships and working with Indigenous partners and communities. We begin with Whetung, who takes a quantitative approach to describe the landscape of cognitive disparities among Indigenous older adults due to structural inequities, in particular, everyday and lifetime discrimination experiences. Next, Blind et al. describe the in-depth and iterative process of cultural adaptation of cognitive assessments. They are currently adapting validated cognitive assessments for Indigenous populations in Canada, this time for urban and reservation-residing American Indian populations. The final presentations by Jacklin et al. and Lewis will focus on qualitative research of cultural explanatory models and lived experience of dementia from the viewpoints of two different participant groups: healthy older adults (Indigenous communities in Minnesota, Wisconsin, and Ontario) and caregivers of people living with dementia (Alaska Native). ADRD research with Indigenous Peoples is scarce but growing, and this symposium highlights the innovate, various, and exceptional approaches to this research. This symposium highlights research projects which are rooted in the values of Indigenous knowledges and research methods, community-based participatory research, qualitative research, and the Six Rs of research (respect, relationship, representation, relevance, responsibility, reciprocity; Tsosie et al. 2022). Using these approaches, our research seeks to understand and close the equity gap for Indigenous older adults dealing with ADRD. Indigenous Peoples Interest Group Sponsored Symposium
INDIGENOUS EXPLANATORY MODELS OF DEMENTIA: RESULTS FROM HEALTHY OLDER ADULTS IN NORTH AMERICA
Authors: Jacklin Kristen , Blind Melissa , Warry Wayne , Lambrou Nickolas , Gleason Carey , Zuelsdorff Megan , Ketcher Dana 
Published: January 2025

Abstract
Explanatory models of illness are important concepts in understanding a person’s beliefs about an illness and the social meaning that is attributed to that illness. This project seeks to understand an explanatory model of Alzheimer’s disease and related dementias (ADRD) among healthy older adults in four diverse Indigenous communities in the US (Minnesota, Wisconsin) and Canada (Ontario). Individual interviews (n=37) were conducted with healthy older adults whose age ranged from 49-79 years (M = 65.5) and were majority female (n=23, 62.2%). Four qualitative analysts conducted team-based coding, double-coding 30% of interviews to ensure intercoder agreement Kappa of ≥.80. A priori codes developed based on Kleinman’s explanatory model resulted in seven content areas: perceptions of ADRD, causes of ADRD, naming ADRD, ADRD treatment and/or care, diagnosis of ADRD/memory concerns, ADRD prevention, and fear/worry regarding ADRD. Themes under these content areas were varied but are reflective of holistic worldviews of health including physical, mental, cultural, and spiritual impacts. For example, participants report that changes associated with dementia align with completing the circle of life, so Elders may share similar traits as infants in terms of help and support. The consequences of ADRD are felt at both interpersonal and community levels, with the loss of traditional knowledge, generational memory, and stories. The default form of ADRD care is within families, with participants reporting that people should live as long as possible at home. This study provides comprehensive information about healthy older adults’ attitudes and perceptions of ADRD in Indigenous communities.
AMICA DEMENTIA SCREENING TOOLS ADAPTATION: AN INTERCULTURAL CONSENSUS APPROACH
Authors: Blind Melissa , Cavanaugh Sheamus , Tsosie Nathania , Trojanczyk Carrie , Lambrou Nickolas , Gleason Carey , Parker Tassy , Jacklin Kristen 
Published: January 2025

Abstract
Existing clinical tools for assessing dementia demonstrate varying degrees of cultural, educational and language biases, and are not validated for use with Indigenous populations in the US. The American Indigenous Cognitive Assessment (AMICA) project aims to develop and validate a culturally appropriate dementia evaluation toolkit that consists of four assessments. Participating Indigenous populations include the Red Lake Nation in Minnesota; an urban Indigenous population receiving services at the First Nations Community HealthSource in Albuquerque, New Mexico; and the Oneida Nation in Wisconsin. Our goal is to create one set of assessments that is agreed upon through intercultural consensus. Assessment adaptation across the three sites will focus on the Canadian Indigenous Cognitive Assessment (CICA), Kimberley Indigenous Cognitive Assessment (KICA) Carer, KICA Depression Scale, and KICA Activities of Daily Living (ADLs). We use a community-based participatory research (CBPR) approach and the Two-Eyed Seeing integrated knowledge framework to engage Tribal and community collaborators. In this paper, we detail the process of convening Indigenous Knowledge Advisory Groups (IKAGs) at each site and an Assessment Expert Panel (AEP), building a team science approach, and facilitating tool adaptation with communities. We provide an update on the CICA adaptation and offer lessons learned that inform culturally relevant and safe adaptation of the remaining tools. Finally, we report on our process for achieving intercultural consensus in developing a single set of dementia assessment tools for Indigenous peoples across the US.
COMPASSIONATE CAREGIVING: ENHANCING GERIATRIC SUPPORT THROUGH GWEP CNA INITIATIVES
Authors: Cotton Samantha 
Published: January 2025

Abstract
The Geriatric Workforce Enhancement Programs (GWEPs) at various institutions have launched innovative educational efforts to support Certified Nursing Assistants (CNAs), a key yet often overlooked segment of the healthcare workforce. These initiatives strive to mitigate high turnover rates and fill educational gaps, with a special focus on leadership, geriatric care, and compassionate handling of individuals with Alzheimer’s disease and related dementias (ADRD). The University of Chicago Medicine’s SHARE Network introduced the CNA Leadership Academy, aimed at nurturing CNAs’ leadership capabilities through a curriculum that includes leadership principles, quality improvement, and resilience, facilitated by Project ECHO’s tele-mentoring. The University of California-Irvine GWEP’s program, “Building Resiliency While Advancing Your Caregiver Skills,” targeted geriatric care enhancements, incorporating the 4-Ms and strategies for challenging behaviors through interactive and trauma-informed teaching methods. Meanwhile, the University of Louisville’s GWEP developed a compassionate care model for CNAs in long-term care, offering training via online modules, workshops, and an iOS app to improve management of ADRD-related behaviors. These GWEPs collectively aim to bolster CNAs’ roles in healthcare, equipping them with essential skills to elevate patient care, especially in geriatric and dementia settings. By enhancing CNAs’ abilities and job satisfaction, these programs contribute to a more resilient, knowledgeable, and empathetic geriatric care workforce, demonstrating a comprehensive effort to advance the quality of care for older adults. This symposium will focus on the critical need of strengthening the training of CNAs and lessons learned across our programs.
FOSTERING COMPASSIONATE CAREGIVING USING CNA TRAINING
Authors: Cotton Samantha 
Published: January 2025

Abstract
Behavioral health complications in individuals with Alzheimer’s disease and related dementias (ADRD) present significant challenges in long-term care facilities. The progressive decline in cognitive abilities and subsequent difficulty in managing behaviors related to ADRD necessitate a specialized approach for Certified Nursing Assistants (CNAs) who provide daily care. Addressing these challenges, our HRSA funded Geriatric Workforce Enhancement Program (GWEP) at the University of Louisville has introduced a compassionate care framework tailored for CNAs in long-term care settings. This comprehensive training model equips CNAs with essential skills and knowledge to understand and navigate the behavioral complexities of ADRD. The training encompasses online micro-modules for self-paced learning, interactive workshops for hands-on practice, and an innovative iOS app has been created as a readily available resource for CNAs, offering guidance and support for managing challenging behaviors on-the-go. Our training program has successfully educated 175 CNAs, evidenced by significant improvements in knowledge and self-efficacy regarding ADRD care, as measured by a pre-test/post-test design. The GWEP compassionate care initiative has shown promising results in enhancing the capabilities of CNAs in ADRD care. The multi-pronged educational strategy has proven effective in improving behavioral management, indicating a scalable and empowering model for CNAs. This model signifies a progressive shift towards better ADRD care in long-term facilities, ultimately enriching the quality of life for those with ADRD. Further discussions will focus on the broader application of such programs in long-term care environments.
ETHICS AND ACCEPTANCE OF AI
Authors: Cotten Shelia , Khan Aishah , Mobley Catherine , Jing Xia , Obeid Jihad , Goodrich Grant , Baker Hamilton , Hubig Nina 
Published: January 2025

Abstract
Over the past 18 months, artificial intelligence (AI) applications have proliferated and been disseminated across wider audiences than in prior time periods. AI tools are increasingly being used as part of new biomedical devices and may become more integrated into healthcare processes over time. While AI applications may have significant value in healthcare and helping support older adults and individuals across the life course through a variety of mechanisms, if individuals do not perceive these tools as ethical and are not accepting of these new tools, they are likely to fail. Cotten and colleagues report the results of a scoping review designed to assess stakeholder (e.g., patients and healthcare providers) acceptance and willingness to use AI-enabled devices in diagnosis, treatment, and rehabilitation settings. The results of this study identify perceived challenges of integrating AI into healthcare across stakeholder groups and provide suggestions to help advance AI acceptance and reduce ethical concerns.
ENGAGING HIGH SCHOOL STUDENTS TO INCREASE RESEARCH-FOCUSED SMARTWATCH USE BY MULTICULTURAL, RURAL OLDER RESIDENTS
Authors: Luna Catherine , Wiese Lisa , Minor Bryan , Schmitter-Edgecombe Maureen , Cook Diane 
Published: January 2025

Abstract
At the southern tip of Lake Okeechobee in south central FL is a rural, underresourced, racially/ethnically diverse region. Persons age 65/older (21%) are primarily African American (57%), Hispanic American (29%) and Afro-Caribbean (4%). Health disparities prevalent in the “Glades” region extend to low rates of digital access (60%) and digital literacy (55%). When asking residents “what mattered most” (Boykin & Schoenhofer, 2001), two issues were identified as most important to the older adult stakeholders: increasing technological competence and maintaining brain health. We tested aims developed with the community advisory board, which tapped into a little-used resource: local high school students, who trained older adults in use of smartwatches to monitor exercise, respond to prompts regarding ecological momentary assessments, and complete n-back cognitive assessments. Faith-based health educators facilitated the home-based visits between 33 older residents and 22 students, and collected pre-post written measures addressing technological self-efficacy, cognition, and health literacy. The older adults (91%, 30/33) responded to smartwatch prompts with a 77.80% response rate, which was consistent with current EMA standards: An 80% response rate has been recommended as the target for EMA studies (Turner et al., 2017), and a meta-analysis reported 75% in the pooled response rate (Jones et al., 2019). Of interest was that self-reported cognition and the Mini-Cog scores were not related (Pearson’s correlational analysis) to number of smartwatch prompts answered or health literacy. Six categories of recommendations ranging from student concerns to resident suggestions emerged from this work, which will be shared in this presentation.