bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Smartphone-Smartcard Platform for Implementing Contingency Management in Buprenorphine Maintenance Patients With Concurrent Stimulant Use Disorder
Authors: DeFulio Anthony , Furgeson Joshua , Brown Hayley D. , Ryan Shawn 
Published: December 2021

Background and Objectives: Opioid agonist pharmacotherapies are effective in the treatment of opioid use disorder (OUD) but concurrent stimulant use is common and can lead to relapse and treatment drop out. Contingency management in combination with opioid agonist pharmacotherapy has broad beneficial effects in polysubstance users, including promoting drug abstinence and treatment retention, but clinic-based implementation can be burdensome. The present study was conducted to evaluate a contingency management intervention delivered via a smartphone-smartcard platform in OUD patients who had concurrent stimulant use disorder.Methods: Retrospective comparison of (n = 124) patients; half received the contingency management intervention and half were matched controls. Drug use and clinic attendance outcomes over four consecutive 30-day periods were analyzed with regression.Results: The intervention group showed consistently higher rates of drug abstinence and clinic attendance which were significant at the latter two timepoints.Discussion: Smartphone-smartcard platforms can facilitate dissemination of contingency management by surmounting or obviating key barriers to adoption. They appear to be convenient for all stakeholders, are easy to use, and facilitate high-fidelity implementation. Delivering contingency management via a smartphone-smartcard platform produces effects consistent with those observed when the intervention is delivered with substantially costlier and more burdensome in-person procedures.
Long Term Impact on Lung Function of Patients With Moderate and Severe COVID-19. A Prospective Cohort Study
Authors: Qureshi Sonia , Nasir Nosheen , Rashid Naveed , Ahmed Naveed , Haq Zoya , Qamar Farah 
Published: December 2021

Background: In Pakistan, the cases of COVID-19 have declined from 6000 per day in June to 600 in September 2020. A significant number of patients continue to recover from the disease, however, little is known about the lung function capacity among survivors. We aim to determine the long-term impact on lung function capacity in patients who have survived moderate or severe COVID-19 disease in a resource-poor setting.Methods: This prospective cohort study will be conducted at Aga Khan University Hospital (AKUH), Karachi Pakistan. Patients 15 years and above who have survived an episode of moderate or severe COVID-19, have reverse transcriptase-polymerase chain reaction (RT-PCR) positive for COVID 19 (nasopharyngeal or oropharyngeal) will be included. Patients with a pre-existing diagnosis of obstructive or interstitial lung disease, lung fibrosis, lung cancers, connective tissue disorders, autoimmune conditions affecting the lungs, underlying heart disease, history of syncope and those who refuse to participate will be excluded from the study. Pulmonary function will be assessed using spirometry and diffusion lung capacity for carbon monoxide (DLCO) at 3- and 6-months interval from the time of discharge from the hospital. Additionally, a chest X-ray and CT-chest will be performed if clinically indicated after consultation with the study pulmonologist or Infectious Disease (ID) physician. Echocardiogram (ECHO) will be performed to look for pulmonary hypertension at the 3 month visit and repeated at 6 months in case any abnormality is identified in the initial ECHO. Data analysis will be performed using standard statistical software. The study was approved by the Ethical Review Committee (ERC) of the institution (ERC reference number 2020-4735-11311).Strengths and Limitations of the Study: This cohort study will provide evidence on the long-term impact on lung function among COVID-19 survivors with moderate to severe disease. Such data will be key in understanding the impact of the disease on vital functions and will help devise rehabilitative strategies to best overcome the effects of disease. However, this will be a single-center, study recruiting only a limited number of COVID-19 survivors.
Exploring the Shift From HIV Pre-exposure Prophylaxis Awareness to Uptake Among Young Gay and Bisexual Men
Authors: Koester Kimberly A. , Erguera Xavier A. , Udoh Ifeoma , Kang Dufour Mi-Suk , Burack Jeffrey H. , Myers Janet J. 
Published: December 2021

Introduction: HIV pre-exposure prophylaxis (PrEP) in the form of a daily oral medication is highly effective at preventing HIV. In the United States, awareness about PrEP has steadily increased over time among individuals vulnerable to HIV, however awareness has not translated into widescale uptake. Estimates are that fewer than 20% of 1.2 million Americans for whom PrEP is indicated are utilizing it. We sought to understand how individuals moved from PrEP awareness to PrEP utilization.Methods: We conducted a series (n = 31) of in-depth interviews with young people, predominantly gay and bisexual men, ages 18–29 years old between February 2015 and January 2016, as part of the evaluation of a multi-year demonstration project funded to test innovative approaches to improve sexual health outcomes and curb the HIV epidemic in California. Interviews were audio-recorded and transcribed verbatim. We conducted a thematic analysis.Results: We present a continuum of PrEP awareness that spans three phases—basic, moderate and advanced. Participants rarely reported becoming well-informed about PrEP over the course of an initial exposure to PrEP information. Learning occurred after multiple exposures to PrEP information through numerous intersecting forms, messengers and formal and informal communication channels. Positively framed messages delivered by formal messengers emphasizing PrEP as a sensible HIV prevention strategy and explicitly communicating a regard for sexual wellness were overwhelmingly persuasive and facilitated movement to the advanced awareness phase. Once participants reached the advanced phase of PrEP awareness, uptake was possible.Conclusions: Our analysis provides insights into how PrEP awareness led to PrEP uptake among young gay and bi-sexual men. Building demand among those in the basic awareness phase took longer than those in the moderate phase. Individuals involved in formal and informal PrEP education can set reasonable expectations about whether, when and how eventual uptake may occur when keeping the continuum of PrEP awareness framework in mind. Many young, gay and bi-sexual male prospective PrEP users will benefit from positively framed messages that emphasize personal well-being, including social, sexual and emotional benefits of PrEP use.
Fitness Facility Staff Can Be Trained to Deliver a Motivational Interviewing-Informed Diabetes Prevention Program
Authors: Dineen Tineke E. , Bean Corliss , Cranston Kaela D. , MacPherson Megan M. , Jung Mary E. 
Published: December 2021

Background: Training programs must be evaluated to understand whether the training was successful at enabling staff to implement a program with fidelity. This is especially important when the training has been translated to a new context. The aim of this community case study was to evaluate the effectiveness of the in-person Small Steps for Big Changes training for fitness facility staff using the 4-level Kirkpatrick training evaluation model.Methods: Eight staff were trained to deliver the motivational interviewing-informed Small Steps for Big Changes program for individuals at risk of developing type 2 diabetes. Between August 2019 and March 2020, 32 clients enrolled in the program and were allocated to one of the eight staff. The Kirkpatrick 4-level training evaluation model was used to guide this research. Level one assessed staff satisfaction to the training on a 5-point scale. Level two assessed staff program knowledge and motivational interviewing knowledge/skills. Level three assessed staff behaviors by examining their use of motivational interviewing with each client. Level four assessed training outcomes using clients' perceived satisfaction with their staff and basic psychological needs support both on 7-point scales.Results: Staff were satisfied with the training (M = 4.43; SD = 0.45; range = 3.86–4.71). All learning measures demonstrated high post-training scores that were retained at implementation follow-up. Staff used motivational interviewing skills in practice and delivered the program at a client-centered level (≥6; M = 6.34; SD = 0.83; range = 3.75–7.80). Overall, clients perceived staff supported their basic psychological needs (M = 6.55; SD = 0.64; range = 6.17–6.72) and reported high staff satisfaction scores (M = 6.88; SD = 0.33; range = 6–7).Conclusion: The Small Steps for Big Changes training was successful and fitness facility staff delivered a motivational interviewing-informed program. While not all staff operated at a client-centered level, clients perceived their basic psychological needs to be supported. Findings support the training for future scale-up sites. Community fitness staff represent a feasible resource through which to run evidence-based counseling programs.
La frontière de l'Etat. Approche historique et juridique
Authors: Bottin Michel 
Published: December 2021

A country and its frontiers. A juridical and historical approach
The image which we have of the frontier is the reflection of ideas and practices inherited from the 19th century. The frontier has not always been an obstacle difficult to cross. History allows us to relativise this approach. We can make the distinction between frontier (zone) and boundary (line). The first is marked by the disappearance of enclaves and the end of the practice of mixed or jumbled up pockets of land ; the second enables us to establish the fact that we had, early on, a very precise idea of this separation. When thinking about the possibilities of frontier (boundary) crossing one should distinguish between the frontier as obstacle and the frontier as point of contact. The first is symbolized by the installation of the customs and the police along the frontier line, the second is associated with the existence of intense neighbour interaction which could well justify a difference of juridical approach.
Dynamique des régions rurales. Une approche localisée
Authors: Guérin Marc , Aubert Francis , Perrier-Cornet Philippe , Sylvestre Jean-Pierre 
Published: December 2021

Dinâmica de las regiones rurales. Un enfoque localizado
Actualmente, los espacios rurales mas periféricos conocen los efectos de las fuerzas económicas que favorecen los fenómenos de aglomeración. Sin embargo, lejos de depender mecânicamente de las leyes de determinismo economico, las regiones rurales enclavadas pueden presentar trayectorias de evolución diversificadas y eficientes. Un marco de anâlisis que subraya la importancia y las formas evolutivas del anclaje social de las empresas (factores de localización, demograffa, organización de los protagonistas sociales) contribuye a explicar la diversidad de estas lógicas de desarrollo. Su aplicación en el valle del Eyrieux (Ardèche) muestra formas concretas de la dinamica económica actual en contexto rural.
Participation dans les démarches qualité et confiance sociale
Authors: Dubois Michel , Doutre Elisabeth , Kouabenan Rémi. D 
Published: December 2021

La participación en la gestion de la calidad y la confianza social
A pesar de su caracter muy técnico y muy racional, los procedimientos de gestion de la calidad tienen una influencia sobre el componente humano de las organizaciones, a la vez al nivel social, organizacional y psicológico. En efecto, la introducciôn de un procedimiento de calidad en una organización, siempre es la oportunidad de muchos trastornos que afectan las costumbres de trabajo, el sistema de relaciones sociales, la posición de los actores, su poder de control, asi como sus competencias y habilidades. El présente artfculo trata particularmente de las relaciones complejas entre los procesos de codificacion y de participaciôn que acompanan generalmente los procedimientos de gestion de la calidad y la confianza social. Nuestras reflexiones se apoyan en un estudio realizado en una empresa del sector aeroespacial.
Les recettes du restaurant. La codification comme moyen de créer des opportunités d'action
Authors: Dubuisson-Quellier Sophie 
Published: December 2021

Las recetas del restaurante. La codificacion como método para crear oportunidades de acción
En el marco de una investigation de la mejora de la calidad de los servicios de una empresa de restauration colectiva, hemos analizado la coproduction de diferentes instrumentes de gestion de la calidad dentro de la organización (procedimiento, dis-positivos técnicos, reglas) y la utilización por los actores operativos de dichos instrumentes destinados a conducir la action. El objetivo del articulo es comprender lo que produce el instrumento de gestion normalizado para el actor que lo utiliza, en el âmbito de una interrogaciôn mas general que estriba en el desplazamiento de la cuestión de la relation a la régla, inducida por la escritura colectiva de estas reglas. La existencia de estos instrumentes codificados abre a los actores nuevos espacios hacia unas acciones locales de ajuste.
Choc exogène et évolution des formes organisations lie s hybrides. Les effets de la crise dite "de la vache folle" sur la filière viande bovine
Authors: Sans Pierre , Fontguyon Guy de 
Published: December 2021

Exogenous shock and hybrid forms : the effect of the «mad cow » crisis on the beef meat supply chain
The «mad cow » crisis, triggered off in March 1996, has produced a great external shock on the French beef supply chain. Using some recent examples, the authors show how the crisis has favoured the development of new forms of co-ordination between all stages of the beef chain (producers, processors and retailers). These have often lead to a product certification. Therefore, when a consumer buys beef, he is able to ascertain the breed, the feeding program and the respect for animal welfare. Finally, the authors propose an analysis of the evolution of the multilateral contracts in the supply chain.
Evaluation of Renal Biomarkers, Including Symmetric Dimethylarginine, following Gentamicin-Induced Proximal Tubular Injury in the Rat
Authors: Hamlin Diane M. , Schultze A. Eric , Coyne Michael J. , McCrann Donald J. , Mack Rebekah , Drake Corie , Murphy Rachel E. , Cross Julie , Strong-Townsend Marilyn , Yerramilli Maha , Leissinger Mary K. 
Published: December 2021

Key Points

This study demonstrates the utility of serum symmetric dimethylarginine (SDMA) as an excretory renal function biomarker in a rat model of gentamicin-induced proximal tubular injury.Analytical and biologic validation of an SDMA immunoassay allows for future studies in rats using a high-throughput method.

Symmetric dimethylarginine (SDMA) is an excretory renal function biomarker shown to correlate well with glomerular filtration rate in dogs, cats, humans, and rats. The objectives of this study were to determine utility of serum SDMA as a renal biomarker in a rat model of gentamicin-induced renal injury and to provide validation of a commercially available SDMA immunoassay for rat serum. Rats were randomly assigned to one of three dose levels of gentamicin (20, 50, or 100 mg/kg) or a vehicle control group and dosed once daily by subcutaneous injection for either four or ten days. Serum and urine renal biomarker evaluation, including serum SDMA, hematologic and serum biochemical analysis, urinalysis, and histologic examination of kidney, were performed. Before biologic validation, analytic validation of the SDMA immunoassay for rat serum was performed, including assessment of assay accuracy, precision, analytical sensitivity, linearity, analyte stability, and interference testing. Among markers of excretory renal function, SDMA and serum creatinine increased earliest and at the lowest gentamicin concentrations and were significantly increased in both the 50- and 100- mg/kg dose levels in the four- and ten-dose treatment groups compared with controls. Time- and dose-dependent increases were noted for all urinary biomarkers investigated in this study, with microalbumin being most responsive and osteopontin least responsive for detection of gentamicin-induced injury across dose levels and schedules investigated. The SDMA immunoassay met all set quality requirements assessed in analytical validation. This study is the first to investigate performance of serum SDMA compared with other excretory renal function markers in a rat gentamicin acute toxicity model. In this study, serum SDMA was an earlier biomarker for detection of gentamicin-induced toxicity than serum cystatin C, BUN, and creatinine clearance. The SDMA immunoassay provides a reliable commercially available assay for future renal investigations in rat models.
Peran Layanan Akademik dengan Kinerja Tutor Sebagai Pemoderasi: Persepsi Mahasiswa S-1 Tuton UPBJJ Ternate
Authors: Hafel Muhlis , Mahdi Suriana AR , Umasugi Mohbir , Jasin Hamida A. , Anfas Anfas 
Published: December 2021

Penelitian ini secara umum bertujuan menguji model teoritikal yang menjelaskan peran kinerja tutor online terhadap hubungan layanan akademik terhadap prestasi belajar mahasiswa. Secara khusus bertujuan untuk menguji dan menganalisis; pengaruh tangible, reliability, responsiviness, assurance dan empaty terhadap prestasi belajar mahasiswa dan menguji pengaruh mediasi kinerja tutor online terhadap layanan akademik dan prestasi belajar mahasiswa. Penelitian ini merupakan penelitian empiris dengan menggunakan teknik probabilitas sampling. Data diperoleh dengan cara menyebarkan kuesioner kepada 351 mahasiswa S-1 yang masa regitrasi tahun akademik 2019-2020 yang tersebar di UPBJJ Ternate. Analisis data dilakukan dengan menggunakan analisis regresi berganda dan mediasi dengan menggunakan analisis moderate regresion analysis (MRA). Hasil penelitian secara parsial menunjukkan bahwa tangible, reliability, responsiviness, assurance dan empaty berpengaruh terhadap Prestasi belajar mahasiswa. untuk moderasi menunjukkan bahwa kinerja tutor online tidak memoderasi pengaruh variabel tangible, reliability, assurance terhadap prestasi belajar mahasiswa. sedangkan kinerja tutor online dapat memoderasi pengaruh variabel responsiviness, empaty terhadap prestasi belajar mahasiswa.
Pengaruh Usia dan Penyakit Ibu dalam Penggunaan Kontrasepsi Tubektomi di Ruang Bersalin RSUD Tgk Chik Ditiro
Authors: Mirdahni Rita , Idawati Idawati 
Published: December 2021

Tubektomi adalah suatu tindakan pemotongan saluran indung telur sehingga sel telur tidak bisa lagi memasuki rahim untuk dibuahi.Tubektomi atau kontrasepsi mantap dilakukan atas indikasi medis seperti seorang ibu yang berpenyakit, kelainan jiwa, kemungkinan kehamilan yang dapat membahayakan nyawa ibu atau penyakit keturunan.Tujuan penelitian ini untuk mengetahui apakah pengaruh usia dan penyakit ibu dalam penggunaan kontrasepsi tubektomi di ruangan bersalin Rumah Sakit Umum Daerah Tgk Chik Ditiro. Metode yang digunakan dalam Penelitian ini adalah metode survey analitik dengan pendekatan retrospektif. Pengumpulan data mengisi lembar checklist. Sampel yang digunakan adalah sebanyak 72 responden (36 kasus dan 36 kontrol). Hasil penelitian menggunakan uji Chi square dengan α=0,05 diperoleh usia (p=0,033), riwayat penyakit (p=0,563). Maka dapat disimpulkan bahwa ada pengaruh usia terhadap penggunaan kontrasepsi tubektomi, serta tidak ada hubungan riwayat penyakit terhadap penggunaan kontrasepsi tubektomi.
Analisis Penyebab Kegagalan Pemberian Asi Eksklusif pada Bayi di RSUD Tgk. Chik Ditiro Kabupaten Pidie
Authors: Idawati Idawati , Mirdahni Rita , Andriani Susi , Yuliana Yuliana 
Published: December 2021

Menyusui memegang peranan penting terhadap tumbuh kembang bayi, kegagalan untuk memberikan ASI eksklusif dapat menyebabkan tingginya angka kejadian penyakit. Penelitian ini bertujuan untuk menganalisis penyebab kegagalan pemberian ASI Eksklusif pada bayi di RSUD Tgk. Chik Ditiro Kabupaten Pidie. Metode : jenis penelitian yaitu analitik dengan pendekatan crossectional, populasi adalah semua ibu bersalin dan menyusui yang berjumlah 85 orang. Hasil Penelitian : Hasil penelitian untuk variabel pengetahuan diperoleh nilai p= 0,000, variabel sikap diperoleh p= 0,000, variabel peran penolong persalinan diperoleh p= 0,000, variabel tradisi diperoleh p= 0,000 yang artinya variabel tersebut memiliki hubungan dengan pemberian ASI eksklusif pada bayi sedangkan variabel umur ibu diperoleh nilai p= 0,131, variabel pendidikan diperoleh p= 0,526, variabel pekerjaan diperoleh nilai p= 0,576, variabel pendapatan diperoleh p= 0,271, variabel paritas diperoleh p= 0,477, variabel usia bayi diperoleh nilai p= 0,560, variabel prilaku diperoleh nilai p= 0,402 yang artinya variabel tersebut tidak memiliki hubungan dengan pemberian ASI eksklusif pada bayi. Kesimpulan : variabel yang paling dominan berpengaruh terhadap pemberian ASI eksklusif pada bayi yaitu variabel peran penolong persalinan.
Keanekaragaman Jenis dan Kepadatan Zooplankton di Perairan Pulau Makassar Kota Baubau
Authors: Failu Ismail , Azizu Azelia Monica , Kasman Kasman , Sofyan Sofyan 
Published: December 2021

The purpose of the study was to determine the type and amount of zooplankton in the waters of Makassar Island, Baubau City. From the results of this study, it is expected that significant information regarding the types and zooplankton found in the sea around Makassar Island, Baubau City, whose waters are suitable for aquaculture. Furthermore, it is hoped that the results of this study can help improve and optimize the use of aquatic biological resources in the future. This research was conducted in the waters of Makassar Island, Baubau City, from August to October 2021. Sample identification was carried out at the Biology Laboratory of the Muhammadiyah University of Buton.
The tool in this research field is plankton net no. 25 to filter zooplankton, GPS determines the sampling location, thermometer measures temperature, handrefactometer measures salinity, DO (Dissolved Oxygen) meter measures sea air oxygen, plastic bottles store seawater samples, small plastic bottles store zooplankton samples, and cool boxes for storing samples. Materials in the field are label paper and markers to label the sample, 70% alcohol to preserve the sample, and aqua water to sterilize the instrument. 1) From the three highest locations found 18 genera of zooplankton belonging to the Crustacea group. 2) With 33 ind/l, the genus OIthona dominates the waters of Makasar Island, Baubau City. 3) In the three locations, there was no variation in zooplankton density.
Elucidation of PVD MoS2 film formation process and its structure focusing on sub-monolayer region
Authors: Ono Ryo , Imai Shinya , Kusama Yuta , Hamada Takuya , Hamada Masaya , Muneta Iriya , Kakushima Kuniyuki , Tsutsui Kazuo , Kano Emi , Ikarashi Nobuyuki , Wakabayashi Hitoshi 
Published: December 2021

Abstract
Sputtering enables uniform and clean deposition over a large area, which is an issue with exfoliation and chemical vapor deposition methods. On the other hand, the process of physical vapor deposition (PVD) film formation has not yet been clarified. We prepared several samples from the sub-monolayer region, and performed Raman spectroscopy, X-ray photon spectroscopy and high-angle annular dark-field scanning transmission electron microscopy. From these results, the internal stresses inherent to PVD films, the bonding states specific to sub-monolayers, and the unique film structure and the grain formation process of PVD films were discussed from the perspective of sub-monolayers. As a conclusion, we found that it is important to suppress the formation of sub-monolayers on the substrate to completely form the first layer.