bluuebunny/crossref_metadata_2025_split huggingface dataset:
Field Response and Surface-Rupture Characteristics of the 2020 M 6.5 Monte Cristo Range Earthquake, Central Walker Lane, Nevada
Authors: Koehler Rich D. , Dee Seth , Elliott Austin , Hatem Alexandra , Pickering Alexandra , Pierce Ian , Seitz Gordon 
Published: January 2021

AbstractThe M 6.5 Monte Cristo Range earthquake that occurred in the central Walker Lane on 15 May 2020 was the largest earthquake in Nevada in 66 yr and resulted in a multidisciplinary scientific field response. The earthquake was the result of left-lateral slip along largely unmapped parts of the Candelaria fault, one of a series of east–northeast-striking faults that comprise the Mina deflection, a major right step in the north–northwest structural grain of the central Walker Lane. We describe the characteristics of the surface rupture and document distinct differences in the style and orientation of fractures produced along the 28 km long rupture zone. Along the western part of the rupture, left-lateral and extensional displacements occurred along northeasterly and north-striking planes that splay off the eastern termination of the mapped Candelaria fault. To the east, extensional and right-lateral displacements occurred along predominantly north-striking planes that project toward well-defined Quaternary and bedrock faults. Although, the largest left-lateral displacement observed was ∼20  cm, the majority of displacements were &lt;5  cm and were distributed across broad zones up to 800 m wide, which are not likely to be preserved in the geologic record. The complex pattern of surface rupture is consistent with a network of faults defined in the shallow subsurface by aftershock seismicity and suggests that slip partitioning between east-striking left-lateral faults and north to northwest-striking right-lateral faults plays an important role in accommodating northwest-directed transtension in the central Walker Lane.
Endometriosis and ART outcome: a retrospective analysis
Authors: S. Janani , Shankar Kundavi , V. Geetha , Basith Abdul 
Published: January 2021

Background: Endometriosis affects up to 30-40% of women seeking fertility treatment and is known to reduce fecundity. There remains a debate on the effect of endometriosis on the IVF outcome, with live birth not reported in most studies. This study looks at the impact of endometriosis on live birth rates after IVF and compares the chances of success with those without endometriosis.Methods: Retrospective analysis of women who underwent IVF at our institution for 2 years were included. Multiple factor infertility, ovulation disorders and donor program were excluded. The outcomes were compared for 4 cohorts - women with endometriosis, male factor infertility, tubal factor infertility and unexplained infertility. The primary outcome was live birth rate. Other outcome measures were total dose of gonadotropins used, mean number of oocytes collected, M2 oocyte rate, fertilization rate, implantation rate, and clinical pregnancy rate.Results: Patients diagnosed with endometriosis had lower mean number of oocytes collected (6.86 vs 7.69, 7.94, 7.45) and lower mean number of M2 oocytes (5.31 vs 6.21, 6.44, 5.91) but was not statistically significant. Endometriosis patients required significantly higher dose of gonadotropins when compared to controls (5365.79 IU; p-0.001). The per ET implantation rate (10.4% vs 17.8%, 22.5%, 19.2%), clinical pregnancy rate (8% vs 15%, 20%, 17%), live birth rate (7.92% vs 16.6%, 15.14%, 12%) and the cumulative live birth rate (27.9% vs 46.5%, 60%, 46.7%) were significantly less in women with endometriosis (p-0.039, p-0.021, p-0.001, p-0.039 respectively) and the effect is more pronounced with increasing disease severity.Conclusions: Endometriosis affects all aspects of IVF outcomes including folliculogenesis, embryo development and implantation. Though ovarian factor can be overruled by increasing the stimulation doses as in our study, methods to improve the implantation rates should be thought about in future.
A POPULAÇÃO IDOSA E A INTERNET
Authors: De Melo Martins Paulo Fernando , Gama da Silva Eder , Marrelli Matos Mauricio Nathanni 
Published: January 2021

Analisar o uso da internet pela população de idosos no Brasil. A metodologia utilizada será por meio de estudo qualitativo, através de um levantamento bibliográfico, verificando-se os estudos bibliográficos sobre o uso da internet a nível nacional. A utilização da internet é a mais imediata ao se comparar com outras tecnologias, tais quais a eletricidade, o automóvel ou ainda a televisão, todavia, ainda persiste um grupo de pessoas que comprova pouca adjacência com essas tecnologias: Os idosos. Como efeito, demonstraremos que há um crescimento no número de uso à internet por essa parcela da população, os idoso e com previsão de aumento.
Analysis of the Need for Nurse Competency Training at Ahmad Yani Islamic Hospital Surabaya
Authors: Muhadi Muhadi , Efendi Ferry 
Published: January 2021

<p><em></em><strong><em>Abstrack</em></strong></p><p><strong><em>Introduction</em></strong><em>: Minimum service standards field of administration and management about employee training require at least 20 hours per year. The aims of this study was to analyze the training needs of nurses at the Ahmad Yani Islamic hospital in Surabaya. In addition, this study explain the organizational analysis, conduct operational analysis, explain individual analysis nurse staff and prioritize nurse training needs in Ahmad Yani Islamic Hospital Surabaya. <strong>Method</strong>: This research is a observational description. The number of respondents about 55 nurses participating the study. <strong>Results</strong>: Based on the aspect of quantity of work, the workload of nurses is classified as high by 49.1%. Most have applied a high quantity of work aspects as much as 78.1%. In the aspect of quality of work, most nurses have performed high tasks. <strong>Conclusion</strong>: Analysis of organizations related to organizational climate at Ahmad Yani Islamic hospital in general was described by nurses in good condition. There are a number of things that need to be considered, namely guaranteed nurse self development through Training, work protection for nurses, nurse remuneration needs to be improved. Operational analysis related to the general competence of nurses in the nurse law is quite capable and most nurses have already taken action. Operational analysis relating to the priority of nurses' training needs is a main priority.</em></p><p> Keywords: <em>Operational Analysis; Individual Analysis; Nurse Training Priority.</em></p>
Implementasi Permainan Kecil Sebagai Bentuk Pemanasan Terhadap Minat Siswa dalam Pembelajaran Pendidikan Jasamani
Authors: Kurnia Dedi , Septiana Rama Adha 
Published: January 2021

Pemanasan merupakan aktivitas penting sebelum melakukan pembelajaran inti dalam pembelajaran penjas. Namun, ketika melakukan pemanasan masih banyak siswa yang melakukannya dengan seadanya dan kadang ada yang tidak mengikutinya dengan alasan bosan dengan gerakannya. Adanya modifikasi pemanasan dengan permainan kecil perlu dilakukan agar siswa berminat untuk mengikuti pembelajaran penjas. Oleh sebab itu, penelitian ini bertujuan untuk mengetahui implementasi permainan kecil sebagai bentuk pemanasan terhadap minat siswa dalam pembelajaran Pendidikan Jasmani. Populasi sebanyak 128 kelas VIII SMPN 1 Sucinaraja, Kabupaten Garut. Sampel dalam penelitian ini adalah siswa yang berjumlah 38 siswa yang diambil menggunakan teknik cluster random sampling. Penelitian ini menggunakan metode eksperimen. Metode pengumpulan data menggunakan angket minat yang sudah diuji validitas dan reliabilitany dengan p=0.88. Hasil penelitian ini menunjukan bahwa terdapat pengaruh yang signifikan pada implementasi permainan kecil sebagai bentuk pemanasan terhadap minat siswa dalam pembelajaran Pendidikan Jasmani yang ditunjukan dengan uji signifikansi dengan uji T dari hasil perhitungan dapat disimpulkan bahwa T tabel dengan dk (n-2) = 36 yaitu 1,688 lebih kecil dari T hitung sebesar 434,934 ( 1,688 < 434,934). Modifikasi permainan kecil sebagai pemanasan harus tetap dilakukan dan diperbaharui untuk menjaga minat siswa ketika belajar penjas.
Authors: Marundha Ainy Sucianti , Angeliqa Fitria 
Published: January 2021

Survey data on the SDKI in 2017 states that alcohol consumption in youth aged 15-19 years, reaches 70% in boys and 50% in girls. Social media is a new media platform which open for everyone that able to access it. Instagram, as one of the social medias is used by brands as an advertising and brand building platform. One of the brand that uses Instagram is Anggur Orang Tua as a brand that has existed since 1984 in Indonesia. The use of Instagram by Anggur Orang Tua displays representations through signs in images and narattive texts which they upload on their instagram account. Signs that produce meaning and representation on Anggur Orang Tua’s instagram account analyzed in this research with Roland Barthes’ semiotics analysis. Through the analysis, the operationalization of codes which is content appealing to youth (CAY) that contained in the uploads is analyzed for its presence. The results showed that the presence of content appealing to youth’s feature is found in the upload and brand represents alcoholic drinks with positive representations as a friend, as well as a parent through their instagram uploads.

Keywords: Representation, content appealing to youth, youth, Alcoholic beverages
High oil accumulation in tuber of yellow nutsedge compared to purple nutsedge is associated with more abundant expression of genes involved in fatty acid synthesis and triacylglycerol storage
Authors: Ji Hongying , Liu Dantong , Yang Zhenle 
Published: January 2021

Abstract
Background: Yellow nutsedge is a unique plant species that can accumulate up to 35% oil of tuber dry weight, perhaps the highest level observed in the tuber tissues of plant kingdom. To gain insight into the molecular mechanism that leads to high oil accumulation in yellow nutsedge, gene expression profiles of oil production pathways involved carbon metabolism, fatty acid synthesis, triacylglycerol synthesis, and triacylglycerol storage during tuber development were compared with purple nutsedge, the closest relative of yellow nutsedge that is poor in oil accumulation. Results: Compared with purple nutsedge, high oil accumulation in yellow nutsedge was associated with significant up-regulation of specific key enzymes of plastidial Rubisco bypass as well as malate and pyruvate metabolism, almost all fatty acid synthesis enzymes, and seed-like oil-body proteins. However, overall transcripts for carbon metabolism toward carbon precursor for fatty acid synthesis were comparable and for triacylglycerol synthesis were similar in both species. Two seed-like master transcription factors ABI3 and WRI1 were found to display similar transcript patterns but were expressed at 6.5- and 14.3-fold higher levels in yellow nutsedge than in purple nutsedge, respectively. A weighted gene co-expression network analysis revealed that ABI3 was in strong transcriptional coordination with WRI1 and other key oil-related genes. Conclusions: These results implied that pyruvate availability and fatty acid synthesis in plastid, along with triacylglycerol storage in oil bodies, rather than triacylglycerol synthesis in endoplasmic reticulum, are the major factors responsible for high oil production in tuber of yellow nutsedge, and ABI3 most likely plays a critical role in regulating oil accumulation. This study is of significance with regard to understanding the molecular mechanism controlling carbon partitioning toward oil production in oil-rich tuber and provides a valuable reference for enhancing oil accumulation in non-seed tissues of crops through genetic breeding or metabolic engineering.
Construction and validation of a novel eight-gene risk score to predict the progression and prognosis of bladder cancer
Authors: Wang Ruiliang , Zheng Zongtai , Mao Shiyu , Zhang Wentao , Liu Ji , Li Cheng , Liu Shenghua , Yao Xudong 
Published: January 2021

Abstract
Background: The progression from non-muscle-invasive bladder cancer (NMIBC) to muscle-invasive bladder cancer (MIBC) increases the risk of death. It is therefore important to find new relevant molecular models that will allow for effective prediction of the progression of bladder cancer (BC).Methods: Using RNA-Sequence data of 49 BC patients in our center and weighted gene co-expression network analysis methods, a co-expression network of genes was developed from which three key modules with prognostic value were selected using Univariate Cox regression in The Cancer Genome Atlas Program (TCGA). Subsequently, an eight-gene risk score was established using the Least absolute shrinkage and selection operator Cox model. Results: A novel eight-gene risk score was closely related to the malignant clinical features of BC and could predict the prognosis of patients in the training dataset (TCGA) and two validation sets (GSE3289 and GSE13507). Further, a nomogram for predicting the overall survival of patients was designed. The nomogram showed good calibration with clinical value through decision curve analysis. Lastly, we found that the mRNA and protein expression level of the eight genes were found to be differentially expressed in cell lines and tissue.Conclusions: In our study, we established a novel eight-gene risk score which could predict the progression and prognoses of BC patients.
Cardiac Tyrosine Hydroxylase Activation and Mb-Comt in Dyskinetic Monkeys
Authors: Cuenca-Bermejo Lorena , Almela Pilar , Gallo-Soljancic Pablo , Yuste José , Pablos Vicente de , Bautista-Hernández Victor , Fernández-Villalba Emiliano , Laorden María-Luisa , Herrero María-Trinidad 
Published: January 2021

Abstract
The impact of age-associated disorders is increasing as the life expectancy of the population increments. Cardiovascular diseases and neurodegenerative disorders, such as Parkinson’s disease, have the highest social and economic burden and increasing evidence show interrelations between them. Particularly, dysfunction of the cardiovascular nervous system is part of the dysautonomic symptoms of Parkinson’s disease, although more studies are needed to elucidate the role of cardiac function on it. We analyzed the dopaminergic system in the nigrostriatal pathway of Parkinsonian and dyskinetic monkeys and the expression of some key proteins in the metabolism and synthesis of catecholamines in the heart: total and phosphorylated (phospho) tyrosine hydroxylase (TH), and membrane (MB) and soluble (S) isoforms of catechol-O-methyl transferase (COMT). The dopaminergic system was significantly depleted in all MPTP-intoxicated monkeys. MPTP- and MPTP+L-DOPA-treated animals also showed a decrease in total TH expression in both right (RV) and left ventricle (LV). We found a significant increase of phospho-TH in both groups (MPTP and MPTP+L-DOPA) in the LV, while this increase was only observed in MPTP-treated monkeys in the RV. MB-COMT analysis showed a very significant increase of this isoform in the LV of MPTP- and MPTP+L-DOPA-treated animals, with no significant differences in S-COMT levels. These data suggest that MB-COMT is the main isoform implicated in the cardiac noradrenergic changes observed after MPTP treatment, suggesting an increase in NA metabolism. Moreover, the increase of TH activity indicates that cardiac noradrenergic neurons still respond despite MPTP treatment.
Two-dimensional spatiotemporal Fourier transform with femtosecond pulses for on-chip devices
Authors: Wang Yulong , Min Changjun , Zhang Yuquan , Yuan Xiaocong 
Published: January 2021

Abstract
On-chip manipulation of the spatiotemporal characteristics of optical signals is important in the transmission and processing of information. However, the simultaneous modulation of on-chip optical pulses, both spatially at the nano-scale and temporally over ultra-fast intervals, is challenging. Here, we propose a two-dimensional spatiotemporal Fourier transform (FT) method for on-chip control of the propagation of femtosecond optical pulses and verify this method employing surface plasmon polariton (SPP) pulses on metal surface. By varying space- and frequency-dependent parameters, we demonstrate that the traditional SPP focal spot may be bent into a ring shape, and that the direction of propagation of a curved SPP-Airy beam may be reversed at certain moments to create an S-shaped path. Compared with conventional spatial modulation of SPPs, this method offers potentially a variety of extraordinary effects in SPP modulation especially associated with the temporal domain, thereby providing a new platform for on-chip spatiotemporal manipulation of optical pulses with applications including ultrafast on-chip photonic information processing, ultrafast pulse/beam shaping, and optical computing.
Clinical Presentations and Outcomes in Transplant Patients With COVID-19: A Systematic Review and Meta-Analysis
Authors: Abbas Kirellos , Shah Jaffer , El-Sahat Nahla , Ali Fatmaelzahraa , Mostafa Esraa , Khattab Ebrahem , Sherif Hadeer , Djedid Selma Klouche , Elmamoun Yousra , Abdhalim Nada , Gayed Ramy , Amin Mostafa , Lama Nitu , Alahmar Majd , Mohamed Zeinab , Dabbous Shrouk , Phuong Nguyen , Brown Ashlyn , Varney Joseph , Huy Nguyen 
Published: January 2021

Abstract
Introduction: Transplant patients are a vulnerable group due to their immunocompromised status. Understanding how COVID-19 can present in this group is clinically important. Therefore, we conduct a systematic review and meta-analysis on clinical features and management of transplant patients with COVID-19.Methods: Five databases were searched in May 2020 to include all relevant studies reporting clinical features or outcomes of COVID-19 infection in transplant patients. Data on clinical presentation, outcomes, lab values, imaging, and drug regimen were extracted. CMA software was used for meta-analysis. Protocol was registered in PROSPERO (CRD42020189458).Results: A total of 49 studies were finally included for analysis. Patients mainly complained from fever with event rate 74.40 % (95% CI= 69.4-78.8), cough 61.10% (95% CI= 55.8-66), and dyspnea 46.60% (95% CI= 69.4-78.8). Blood urea nitrogen 78.90% (95% CI= 54.7-92), ESR 78.10% (95% CI=52.3-92.1), and D-dimer 74.10% (95 % CI= 53-87.9) were the most elevated observed laboratory values. Ground glass opacities (GGO) were observed with event rate 68.10% (95% CI= 20.4-94.9). For treatment, immunosuppressants were used in 88.80% (95% CI= 77.6-94.8) of patients, followed by antibiotics and antiviral drugs 68.40% (95% CI= 52.4-80.9), 66.80% (95% CI = 45-83.2), respectively. Mechanical ventilation was used in 26.30% (95% CI=21-32.4) patients while 33.7% (95% CI= 20.7-49.9) intubated. Rejection occurred in 11% (95% CI= 4.4-25) of the patients. Finally, 18.20% (95% CI= 12.6-25.7) died. Conclusion: Clinical characteristics and management in transplant COVID patients suggest the similar course in non-transplant. Fever, cough, dyspnoea, elevated blood urea nitrogen level, elevated CRP, elevated d-dimer, GGO, and consolidation were found to be the most frequent abnormalities. No direct, comparative analysis with non-transplant COVID population limited our results; however, numerous studies that examined the infected general population found similar, less augmented findings. Most of the included sample were kidney transplant patients; therefore, more studies are needed to address other types of COVID-19 infected transplant patients.
Does Socio-economic Inequality Exist in Micro-nutrients Deficiency among Children Aged 6-59 Months in India? Evidence from National Family Health Survey 2005-06 and 2015-16
Authors: Srivast Shobhit , Kumar Shubham 
Published: January 2021

Abstract
Background: The decadal change in Vitamin A and iron supplement deficiency changed at significant levels but still a matter of issue in India. The deficiency of Vitamin-A decreased from 81.9% to 40.5%, and iron supplement deficiency decreased form 95.3% to 73.9% from 2005-06 to 2015-16 among children aged 6-59 months in India. The present study determines the socio-economic inequalities in Vitamin A deficiency (VAD) and Iron deficiency (ID) among children aged 6-59 months in India and to estimate the change in the percent contribution of different socio-economic correlates for such inequality from 2005-06 to 2015-16.Methods: Data from National Family Health Survey (NFHS) 2005-06 and 2015-16 was used for the analysis. Bivariate analysis and logistic regression analysis was used to carve out the results. Moreover, Wagstaff decomposition analysis was used to carry out socio-economic inequality analysis.Results: It was revealed that Vitamin A deficiency was reduced from 85.5% to 42.1% whereas ID was reduced from 95.3% to 73.9% from 2005-06 to 2015-16 respectively. Child’s age, mother’s educational status, birth order, breastfeeding status, place of residence and empowered action group (EAG) status of states were the factors which were significantly associated with Vitamin A deficiency and Iron deficiency among children. Moreover, it was found Vitamin A deficiency and Iron deficiency got more concentrated among children from lower socio-economic strata. A major contribution for explaining the gap for socio-economic status (SES) related inequality was explained by mother’s education, household wealth status, empowered action group status of states for both Vitamin A deficiency and Iron deficiency among children under five years in India.Conclusion: Schemes like the Integrated Child Development Scheme (ICDS) would play a significant role in reducing SES related gap for micro-nutrient deficiency among children in India. Proper implementation of ICDS will be enough for reducing the gap between rich and poor children regarding micro-nutrient deficiency.
Endovascular Therapy of Severe Non-Variceal Gastrointestinal Bleeding – One Decade Experience.
Authors: Vorčák Martin , Sýkora Ján , Ďuriček Martin , Bánovčin Peter , Grendár Marian , Zeleňák Kamil 
Published: January 2021

Abstract
Introduction Severe non-variceal gastrointestinal bleeding is a life-threatening condition with complicated treatment if endoscopic rescue fails. In that case, transcatheter arterial embolization is recommended to stop the bleeding. The technical and clinical effects of this technique were analyzed in this group of patients, as well as its complication rate and 30-day mortality.Method Patient data of the one-decade period (from 2010 to 2019) were analyzed retrospectively. Twenty-seven patients (18 men and nine women, median age 61 years) treated by endovascular embolization in our institution with clinically significant gastrointestinal hemorrhage after unsuccessful or impossible endoscopic treatment were identified.Results The source of bleeding was found in 88% of patients, but embolization was performed in 96% of them. The technical success rate in the sample was 100%, and the clinical favorable outcome rate was 88.5%. The bleeding recurrence occurred in eight cases, five of whom had technically successful re-embolization in four cases. The incidence of recurrent bleeding was significantly higher in patients with two or more comorbidities with (p = 0.043). There was one serious complication (4%) in the group and minor difficulties occurred in 18% of patients; 30-day mortality reached 22%. Mortality was significantly higher in the group of patients with re-bleeding (p = 0.044).Discussion Our documented results in common are in the established rank of previously published results, which range from 62-100% for technical success, 52-94% for the clinical favorable outcome, 9-66% for re-bleeding and 4-46% for 30-day mortality.Conclusion Transcatheter arterial embolization is a safe mini-invasive method with high technical and clinical success in patients with endoscopically untreatable gastrointestinal bleeding. It is also suitable for high-risk cases. Mortality (to a significant extent) typically depends on the re-bleeding presence and the patient's comorbidity.