bluuebunny/crossref_metadata_2025_split huggingface dataset:
Creating a Safe Haven for Children: The Effect of Parent-Child Attachment and Parenting Strategy on Children’s Risk Perceptions to Climate Change
Authors: Zhong Shuang , Cheng Qiu , Jia Guangyuan , Ngok Kinglun 
Published: April 2021

Abstract
Children’s climate change risk perceptions including their attitudes and mitigation behaviors, which are crucial to protect themselves from the consequence of climate extremes. However, recent studies have not identified the complex interplay effects between children’s climate change risk perceptions and their family relationships. This study explored the effects of parent-child attachment, parenting strategies as well as their co-influence on children’s risk perceptions to cope with climate changes through investigating a pilot disaster education program in China. Data was collected from 1,710 children aged 8–12 in 45 primary schools in Sichuan Province in 2018. We used Ordinary Least Square Regression and Principal Component Analysis to evaluate the effects of parent-child attachment, different parenting styles and their co-influencing mechanism on children’s risk perceptions. The results found that frequent parent-children interactions had significantly positive effects on children’s risk perceptions, and these effects were more significant in the single-raised children than the children raised by two parents. We further established a conceptual framework for understanding the different parent-child attachment patterns for children’s climate change risk perception based on a mathematical quadrant between frequent parent-child interactions and available attached figures, and found children’s risk perceptions are varied attributed to different patterns of parent-child attachment. Theoretical implications related to climate change and practical implications for family and community mitigation were discussed.
Baseline Health Risk Assessment of Trace Metals in Bivalve Shellfish From Commercial Growing Areas in the Estuaries of Ashtamudi and Vembanad (Kerala, India)
Authors: Chinnadurai Shunmugavel , de Campos Carlos Jose Alexandre , Geethalakshmi Vaithianathan , Kripa Vasant , Mohamed Kolliyil Sunil 
Published: April 2021

Abstract
Trace metal concentrations were monitored in the yellow clam (Paphia malabarica), green mussel (Perna viridis) and edible oyster (Crassostrea madrasensis) from growing areas in the Ashtamudi and Vembanad estuaries, Kerala. Ranges of mean annual concentrations (mg/kg) were Ni (0.46–0.65); Co (2.87–3.49); Fe (80.0–119.4); Mn (3.88–9.38); Zn (40.8–76.2); Pb (1.28–2.00); Cu (1.59–4.38). In Ashtamudi, clams had higher mean concentrations of Ni, Co, Fe, Mn and Pb than oysters. Mean concentrations of Ni, Pb (in all species), Zn (in clams and mussels) and Cu (in mussels) did not exceed maximum permissible limits mandated by the Food Safety and Standards Authority of India. Mean Mn concentrations exceeded the World Health Organization guideline in the three species while mean Fe concentrations in clams and oysters did not exceed the guideline. Target hazard quotients were generally ≤ 1, except for a few Pb results in clams and mussels. Although results suggest no health risk to consumers for the reference doses, daily intakes and elements considered, regular monitoring of trace metals is recommended to maintain consumer protection given increasing anthropogenic and climatic pressures on the shellfish growing areas.
Catalytic Oxidation of Methylene Blue by Attapulgite/TiO2
Authors: Shang Jianping , Jiang Yu , Qin Xiaoping , Zhao Bin , Li Xuefei 
Published: April 2021

Abstract
Methylene blue(MB) is a common pollutant in wastewater of printing and dyeing. At present, ozone oxidation is commonly used in the treatment of printing and dyeing wastewater. Ozone is oxidized by direct reaction and indirect reaction, However, the reaction rate is not high and it is impossible to completely mineralize organic matter. The experimental scheme is to impregnate the attapulgite(ATP) with a volume of tetrabutyl titanate-ethanol solution. The TiO2/attapulgite nanocomposite with high catalytic activity was prepared. The synthesized samples were subjected to characterized by X-Ray diffraction(XRD). The morphology and particle size of the particles were observed by scanning electron microscopy (SEM). The attapulgite modified by TiO2 was calcined at 300°C for 2 h, and the degradation rate of 80 mg/L methylene blue was 99.8%. The experimental results show that the ozone, temperature and mass transfer factors are excluded, and the effects of temperature, MB concentration and pH on the degradation of methylene blue are investigated. The optimal reaction conditions are as follows: The ozone concentration is 0.067 g/min; the ozone flow rate is 0.15 NL/min; the stirrer rotation speed is 550 r/min; the catalyst is 0.1 g; the temperature is 50°C; Based on the results, the reaction mechanism was derived and the kinetic study of the experiment was carried out.
Dietary intake of branched-chain amino acids in relation to general and abdominal obesity
Authors: Asoudeh Farzaneh , Salari-Moghaddam Asma , Keshteli Ammar Hassanzadeh , Esmaillzadeh Ahmad , Adibi Peyman 
Published: April 2021

Abstract
Purpose: Despite the huge evidence on the link between dietary protein intake and obesity, limited studies have examined the role of individual amino acids in this regard. This study aimed to investigate the association between dietary total and individual BCAAs intake and odds of general and abdominal obesity in a large group of adults.Methods: This cross-sectional study was conducted among 8691 adults aged 18-55 years in Isfahan, Iran. Dietary BCAAs were assessed using a validated dish-based 106-item semi-quantitative food frequency questionnaire (DS-FFQ). Information about weight and waist circumference were collected through a self-reported validated questionnaire. General obesity was defined as body mass index (BMI) ≥30 kg/m2, and abdominal obesity was defined as waist circumference (WC) ≥88 cm for women and ≥102 cm for men.Results: Mean age of study participants was 36.8±8.1 years. Prevalence of general obesity was 9.2% in men and 9.7% in women and that of abdominal obesity was 13.3% and 36.2% in men and women, respectively. We found that participants in the top tertile of total BCAAs intake had higher odds of general obesity compared with those in the bottom tertile (OR: 1.42; 95% CI: 1.09-1.84). Such significant association was seen in men (OR: 1.57; 95% CI: 1.05-2.34), but not in women (OR: 1.33; 95% CI: 0.94-1.89) in our stratified analysis. We found no significant association between total BCAAs intake and odds of abdominal obesity. Stratified by sex, no significant association was observed between total BCAAs intake and odds of abdominal obesity [for men: (OR: 1.10; 95% CI: 0.74-1.65) and for women: (OR: 1.08; 95% CI: 0.84-1.38)]. Assessing the association with individual BCAAs, a significant positive association was observed between dietary intake of valine (OR: 1.42; 95% CI: 1.10-1.84), leucine (OR: 1.43; 95% CI: 1.10-1.86), and isoleucine (OR: 1.42; 95% CI: 1.09-1.84) with general obesity. We observed no significant association between dietary intake of individual BCAAs intake and odds of abdominal obesity.Conclusion: Dietary BCAAs intake was associated with an increased odds of general obesity, in particular among men. No significant association was observed between dietary BCAAs and abdominal obesity.Level of evidence: Level V, descriptive cross-sectional study.
A Novel Ferroptosis-related Gene Signature for Overall Survival Prediction in Patients with Bladder cancer
Authors: Wu Liyuan , Yang Feiya , Xing Nianzeng 
Published: April 2021

Abstract
Background Bladder cancer (BC) is a highly heterogeneous disease, which makes the prognostic prediction challenging. Ferroptosis is related to a variety of biological pathways, including those involved in the metabolism of amino acids, lipids, and iron. However, the prognostic value of ferroptosis-related genes in BC remains to be further elucidated. Methods In this study, the mRNA expression profiles and corresponding clinical data of BC patients were downloaded from public databases. The least absolute shrinkage and selection operator (LASSO) Cox regression model was utilized to construct a multigene signature and validated it. Results Our results showed 12 differentially expressed genes (DEGs) were correlated with overall survival (OS) in the univariate Cox regression analysis (all adjusted P< 0.05). A 9-gene signature was constructed to stratify patients into two risk groups. Patients in the high-risk group showed significantly reduced OS compared with patients in the low-risk group (P < 0.001). The risk score was an independent predictor for OS in multivariate Cox regression analyses (HR> 1, P< 0.01). Receiver operating characteristic (ROC) curve analysis confirmed the signature's predictive capacity. Functional analysis revealed that immune-related pathways were enriched, and immune status were different between two risk groups, especially in humoral immune response process. Conclusion In conclusion, a novel ferroptosis-related gene signature can be used for prognostic prediction in BC. Targeting ferroptosis may be a therapeutic alternative for BC.
Effect of Health Education via Mobile Application in Promoting Quality of Life Among Asthmatic Schoolchildren in Urban Malaysia During the COVID-19 Era: A Quasi-Experimental Study
Authors: Raimi Abdulaziz Mansoor Al , Chong Mei Chan , Tang Li Yoong , Chua Yan Piaw , Ajeel Latifa Yahya Al 
Published: April 2021

Abstract
BACKGROUND: Bronchial asthma among children is a common chronic disease which may have impact on quality of life. Health education is one of the strategy to improve knowledge and quality of life.OBJECTIVE: The study aims to assess the effect of health education via mobile application (app) in promoting quality of life among schoolchildren with asthma in urban Malaysia during the COVID-19 era. METHODS: A quasi-experimental, pre- and post-intervention design was used in this study involving a total of 214 students, randomly assigned into two groups (intervention group and control group). The control group received face-to-face health education while the experimental group received health education via a mobile application.RESULTS: The findings showed that the total score of quality of life (QoL) has improved from a mean total score at pre-intervention (5.31±1.27) to post-intervention (5.66±1.28) for the control group, compared with the experimental group with a mean total score of QoL at pre-intervention (5.01±1.36) and post-intervention (5.85±1.29). A comparison between the experimental and control groups using an independent t-test showed statistically significant differences in their mean QoL scores. The effect of health education via mobile application showed a statistically significant improvement in the mean QoL score from pre- to post-intervention [F (1,288) = 57.46, p = <0.01].CONCLUSION: The use of mobile technology in health education improved QoL as compared to the traditional methods of face-to-face lecture and/or handbooks among schoolchildren with asthma. Thus, educational modules using mobile applications do improve QoL.
Analysis of Two-Dimensional Nonlinear Sloshing in a Rectangular Tank by Using a Concentrated Mass Model
Authors: Yoshitake Tatsuhiro , Ishikawa Satoshi , Kondou Takahiro 
Published: April 2021

Abstract
Major problems can occur when liquid sloshes in a tank, such as occurs in liquid storage tanks during an earthquake, and this is an important engineering problem to address. To analyze this phenomenon, semi-analytical methods such as the perturbation method, the multimodal method, and the finiteelement method are generally used. However, semi-analytical methods involve quite complicated equations, and the finite-element method involves many degrees of freedom when the tank is large. In this paper, a nonlinear numerical model with relatively few degrees of freedom is established for vertical and horizontal two-dimensional nonlinear sloshing in a rectangular tank excited horizontally. The model comprises concentrated masses of liquid connected by nonlinear springs and dampers. The connecting springs have characteristics based on the static and dynamic pressures of the liquid. In addition, a method is proposed for reducing the number of degrees of freedom in the two-dimensional model. The natural frequencies, modes, and frequency responses are then compared among the concentrated-mass model, theoretical calculations, and experimental results. Good agreement was achieved among them, thus demonstrating the validity of the model.
Intense Browsing by Sika Deer (Cervus Nippon) Drives the Genectic Differentiation of Hairy Nettle (Urtica Thunbergiana) Populations
Authors: Kohyama Tetsuo I. , Yoshida Mei , Kimura Masahito T. , Sato Hiroaki 
Published: April 2021

Abstract
Many studies have inferred the way in which natural selection, genetic drift and gene flow shape the population genetic structures, but very few have quantified the population differentiation under spatially and temporally varying levels of selection pressure, population fluctuation and gene flow. In Nara Park (6.6 km2; NP), central Japan, where several hundred sika deer (Cervus nippon) have been protected for more than 1,200 years, heavily- or moderately-haired nettle (Uritica thunbergiana) populations have evolved probably in response to intense deer browsing. Here, we analysed the genetic structure of two populations from NP and five from surrounding areas using amplified fragment length polymorphism markers. A total of 546 marker loci were genotyped from 210 individuals. A Bayesian method estimated 5.5% of these loci to be outliers, which are putatively under natural selection. Neighbour-joining, Bayesian clustering and principal coordinates analyses using all-loci, non-outlier loci and outlier loci datasets showed that the two populations from NP formed a cluster distinct from the surroundings. These results indicate the genome-wide differentiation of the populations from NP and the surroundings. Moreover, these imply that: (1) gene flow is limited between these populations and thus genetic drift is a major factor causing the differentiation; and (2) natural selection imposed by intense deer browsing has contributed to some extent to the differentiation. In conclusion, sika deer seems to have counteracted genetic drift to drive the genetic differentiation of hairy nettles in NP. This study suggests that a single herbivore species could lead genetic differentiation among plant populations.
Study On The Performance Of Carbonate-Mineralized Bacteria Combined With Eggshell For Immobilizing Pb and Cd in Water And Soil
Authors: Wei Ting , Yashir Noman , An Fengqiu , Imtiaz Syed Asad , Li Xian , Li Hong 
Published: April 2021

Abstract
Microbially induced carbonate precipitation (MICP) is an advanced bioremediation approach to remediate heavy metals (HMs) contaminated water and soil. In this study, metal tolerant urease-producing bacterial isolates, namely UR1, UR16, UR20 and UR21, were selected based on their urease activity. The efficiency of these isolates in water for Pb and Cd immobilization was explored. Our results revealed that UR21 had the highest removal rates of Pb (81.9%) and Cd (65.0%) in solution within 72 h through MICP. The scanning electron microscopy-energy dispersive x-ray and x-ray diffraction analysis confirmed the structure and the existence of PbCO3 and CdCO3 crystals in the precipitates. In addition, the strain UR21, in combination with urea/eggshell waste (EGS) or both, was further employed to investigate the effect of MICP on soil enzymatic activity, chemical fractions and bioavailability of Pb and Cd. The outcomes indicated that the applied treatments reduced the proportion of soluble-exchangeable Pb and Cd, resulted an increment in carbonated bound Pb and Cd in the soil. The DTPA extractable Pb and Cd was reduced by 29.2% and 25.2% with the treatment of UR21 + urea + EGS as compared to the control. Besides, the application of UR21 and EGS significantly increased the soil pH, cation exchange capacity, and enzyme activities. Our findings may provide a novel perceptive for an eco-friendly and sustainable approach to remediate heavy metal contaminated environment through a combination of metal-resistant ureolytic bacterial strain and EGS.
Chronic Fluoxetine Enhances Extinction Therapy for PTSD by Evaluating Brain Glucose Metabolism in Rats: An [18F]FDG PET Study
Authors: Liu Jing , Yu Jun , Liu Hong Biao , Yao Qiong , Zhang Ying 
Published: April 2021

Abstract
Recent studies suggest that selective serotonin reuptake inhibitors (SSRIs) and exposure therapies have been used to reduced footshock-induced posttraumatic stress disorder (PTSD) symptoms. However, the therapeutic effect of the combination of SSRIs treatment with exposure therapy remains a matter of debate.This study aimed to evaluate these therapeutic effect through the behavioral and the neuroimaging changes by positron emission tomography (PET) in model rats. We adopted a Pavlovian fear conditioning paradigm to establish model rats, and serial [18F]fluorodeoxyglucose (FDG) PET imaging was performed to investigate the neurofunctional changes before and after the therapies (chronic fluoxetine and/or extinction). Behavioral tests indicated combined therapy group performanced lower freezing (%) than the two other groups.Compared with the baseline, fear conditioning increased 18F-FDG uptake in the right amygdala but decreased uptake in the left primary somatosensory cortex. After extinction retrieval, there was increased [18F]FDG uptake in the left striatum but decreased uptake in the anterior cingulate cortex in the extinction group. Fluoxetine increased [18F]FDG uptake in the left hippocampus but decreased uptake in the cuneiform nucleus. The combined therapy increased [18F]FDG uptake in the left hippocampus, left striatum, right insular cortex but reduced uptake in the cerebellar lobule. c-Fos expression was significantly higher in the hippocampal dentate gyrus and anterior cingulate cortex in the fluoxetine and combined groups than that in the extinction group, with no significant difference between the two groups. Taken together, chronic fluoxetine enhanced the effects of extinction training in a rat model of PTSD. In vivo PET imaging may provide a promising approach for evaluation chronic fluoxetine treatment of PTSD.
River Branch Inspired Janus Textile with Moisture Wicking and UV Resistant Properties
Authors: Zhang Jinju , Sun Juanjuan , Yin Yunjie , Wang Chaoxia 
Published: April 2021

Abstract
Discontinuous hydrophobic/hydrophilic Janus fabric resembling river branches is prepared by nano-ZnO pretreatment and screen printing for directional water transport and thermal conductivity properties. A river branch-like structure is constructed dexterously, and the effect is quantitatively adjusted by accurately regulating the gap width of hexagon water-transfer-channel. Fabrics based on these rivers branch-like hexagon structure possess enhanced moisture wicking performance, a desired water transport index of 147.26%, which are over seven times higher than conventional cotton fabrics. Meanwhile, nano-ZnO treatment improves the thermal conductivity of cotton fabric, which accelerates the evaporation of sweat on the surface of cotton fabric. Moreover, nano-ZnO cotton fabric shows an outstanding UV resistant property with 145 UPF value. The novel discontinuous hydrophobic/hydrophilic Janus fabric could provide a new strategy for the development of moisture management textiles.
Quality Of Referral, Admission Status And Outcome Of Neonates Referred To Pediatric Emergency Of A Tertiary Care Institution In North India
Authors: Mishra Neeraj , Saini Shiv Sajan , Muralidharan Jayashree , Kumar Praveen 
Published: April 2021

Abstract
Background: We evaluated quality of referral, admission status and outcome of neonates.Methods: We enrolled newborns admitted between March 2016 and October 2016, excluding neonates referred from outpatient department. Information was collected from referral slips, interviewing accompanying persons and observation.Results: 61% were referred from government hospitals with “Sick Newborn Care Units” contributing to maximum. Main mode of transport was ambulance in 80% and referral notes were available in the majority but incomplete in majority. Sepsis (39%), jaundice (16%) and birth asphyxia (13%) were most common diagnoses. Half of the newborns were hemodynamically unstable. 27% had poor circulation, 15% were hypoxic, 9% hypoglycemic and 8% hypothermic. 22% either died or “Left Against Medical Advice” with a high probability of death.Conclusion: National ambulance service is utilized for transporting newborns. However, there are quality gaps which need attention to develop it into efficient referral system.
Bisphenol A Acts As Developmental Agonist in Culex Quinquefasciatus Say
Authors: Gayathri Ayana , DA Evans 
Published: April 2021

Abstract
Plastic – derived Bisphenol A (BPA) contaminated sewages in Trivandrum, Kerala, India are mosquito breeding sites. After summer rain, BPA in the stagnant water samples ranged between 0.86 and 1.14ppm. 1.0 ppm BPA is considered as environmentally relevant concentration. Present study revealed that BPA is a developmental agonist of Culex quinquefasciatus. Embryonic and larval development are shortened by BPA but pupal development is unaffected. Under the atmospheric temperature of 26 to 310C lifecycle was completed within 312 hours but during summer it was completed within 278 hours, meanwhile atmospheric temperature ranged between 30 and 370C. Reduction in the duration of development due to BPA was 50 to 70 hours during summer and 60 to 80 hours in other seasons. Larval – pupal stadium of the mosquito has three surges of 20-hydroxy ecdysone(20-HE), at 24,32 and 48th hour of the 4th instar. BPA resulted dose-dependent advancement of 20-HE peaks, Phospholipase A2 induction and expression of Ecdysone receptor EcRA and Ecdysone inducible gene E75A, which culminated in early pupation. Adults emerging from 1.0 ppm BPA treatment did not show significant difference in sanguivory and fecundity compared to control but pupae developed in 2 and 4 ppm BPA were significantly small.
Potentiation of Resistance to Penicillium Spp. In Valencia Sweet Orange Through Use of Salicylic Acid and Methyl Jasmonate
Authors: Iqbal Zafar , Khangura Ravjit , Singh Zora , Rauf Saeed 
Published: April 2021

Abstract
Citrus green and blue moulds cause postharvest losses worldwide. Therefore, the potential of preharvest foliar application of salicylic acid (SA) and methyl Jasmonate (MeJ) was investigated to control infection of Penicillium spp. An aqueous solution containing different concentrations of SA (3, 6, 9 mM) or MeJ (3, 4, 5 mM) and ‘Tween 80’ (0.05%) as a surfactant were sprayed onto whole trees seven days before harvest. Among the treatments, the pre-harvest spray of SA (9 mM or MeJ 5 mM) showed good efficacy reducing colony growth, wound rotting (rotting of peel around the wound and spore mass density of Penicillium spp. when compared with control. A pre-harvest spray of SA (9 mM) reduced colony growth by 71.02% and 68.69% on fruit inoculated with P. digitatum and P. italicum, respectively. The activity of fruit softening enzymes markedly increased following fungal infection. The decay in the fruit was found to be associated with the upregulation of activities of exopolygalacturonase (exo-PG), endopolygalacturonase (endo-PG) and Endo-1,4-ß-D-glucanase (e-gase). However, in un-inoculated fruit, negligible enzyme activity was observed. Contrarily the SA-treated fruit showed less activity of exo-PG, endo-PG and e-gase enzymes. These findings clued to develop natural control of Penicillium spp through use of organic elicitors in sweet orange fruit.