bluuebunny/crossref_metadata_2025_split huggingface dataset:
Minimally invasive transforaminal lumbar interbody fusion
Authors: Kanala Reddy Ramanadha , Yerragunta Thirumal , Yerramneni Vamsi Krishna , Kolpakawar Swapnil , Kumar K. S. Vishwa , Suman Arvind 
Published: December 2021

Background:
Current trends in spine surgeries have shifted to minimally invasive procedures. Minimally invasive approaches are getting more popular for lumbar interbody fusion procedures.

Objectives:
The objective of the study was to report technical modifications, learning curve, and short-term clinical results in minimally invasive transforaminal interbody fusion (MITLIF).

Materials and Methods:
All MITLIF cases performed from 2018 July to March 2020 were included. First three authors were operating surgeons. Visual analog scores (VAS) scoring for pain, Macnab criteria, and Oswestry disability index (ODI) were used for outcome assessment. Operating time, radiation exposure, and complications were assessed separately in a group of 20 as per time sequence in series to assess the learning curve.

Results:
A total of 61 patients were included. Various indications included spondylolisthesis, failed back surgery, calcified lumbar disc, and spondylodiscitis. Mean age was 47.08 ± 12.06. Intraoperative blood loss was 97.04 ± 25.58. Mean operating time and number of C-arm shots were 190.75 ± 37.11 and 159.3 ± 74.54, respectively, in initial 20 cases which however reduced in later operated cases. Significant improvement in VAS and ODI scores was observed at follow-up of 6.34 ± 4.67 months. Three cases needed surgical revision in the initial 20 cases, and there were no revision surgeries in later operated cases.

Conclusion:
MITLIF could be done in failed back surgery cases, spondylodiscitis, and deformity corrections in addition to spondylolisthesis. It has advantages of less injury to soft tissues, maintaining the posterior tension band, decrease in blood loss and hospital stays, and early mobilization. However, it has longer learning curve and takes minimum 20 cases for the surgeon to acquire reasonable experience and confidence.
Outcomes of chordomas of the sacrum and mobile spine
Authors: Zileli Mehmet , Karakoç Habib Tadayyon Einaddin 
Published: December 2021

Study Design:
Retrospective clinical series.

Purpose:
To search for spinal chordoma's survival rates, recurrences, and complications and compare sacral and mobile spine chordomas.

Overview of Literature:
The primary spinal chordoma treatment is mainly considered radical surgery, although recurrence rates are pretty high. Radical surgery with extra marginal resection is possible with significant neurologic deficits and very high complication rates.

Materials and Methods:
This study reviews 48 spinal chordoma patients (sacrum 28, mobile spine 20) surgically treated between 1995 and 2019. Follow-up times ranged between 12 months and 238 months (average 6.16 years). Six patients were lost to follow-up after at least 1 year of control; three died 30 days after surgery.

Results:
Surgery for sacrum tumors was an extra marginal resection (sacrectomy) in 19 patients, while nine patients had intralesional surgery. There were 13 cervical chordomas and seven thoracolumbar chordomas. Although we tried marginal resections for cervical chordomas, all had positive margins, and we accepted them as intralesional. Surgery for thoracolumbar chordomas was total spondylectomy in four cases and intralesional excision in three patients. Because of recurrences, the average surgery per patient was 3.45. It was more common in mobile spine chordomas (average 4.2) than sacral chordomas (average 2.92). Surgical complications of mobile spine chordomas (15/20; 75%) were also more than sacral chordomas (16/28; 57%). Chordomas of the mobile spine had no metastasis, while sacral chordomas had a 21% (6/28) metastasis rate. The recurrence rates of sacral chordomas (16/21; 76%) were not significantly different from the mobile spine (15/18; 83%). Among sacral chordomas, in all five cases who had no recurrence, the level of sacrectomy was S2 and below.

Conclusions:
Recurrence and survival rates of mobile spine and sacral chordomas are not different. Sacral chordomas tend to metastasize. Sacrectomy is successful for sacral chordomas at S2 and below.
Minimally invasive cervical laminoforaminotomy – Technique and outcomes
Authors: Srikantha Umesh , Hari Akshay , Lokanath Yadhu K 
Published: December 2021

Background:
Cervical radiculopathy is a common pathological entity encountered by spine surgeons. Many surgical options have been described including anterior cervical discectomy with or without fusion to arthroplasty and posterior cervical laminoforaminotomy. Being a motion-preserving procedure, posterior cervical laminoforaminotomy is an excellent treatment for patients with unilateral radiculopathy secondary to a laterally located herniated disc or foraminal stenosis. With the advent of minimally invasive techniques, this procedure has regained popularity.

Objectives:
Although there is enough evidence in the literature highlighting the benefits, safety, and efficacy of minimally invasive versus conventional techniques, a detailed technical report along with long-term surgical outcomes is lacking.

Methods:
The authors present their experience in minimally invasive cervical laminoforaminotomy (MIS-CLF) over a 7-year period (2013–2020) along with a technical note. Clinical evaluation was performed both before and after surgery, using the Visual Analog Scale (VAS) pain scores. Patient functional outcome was measured using the modified Odom's criteria.

Results:
There were no major perioperative complications. No patient required surgery for the same level during the follow-up period which ranged from 1 to 3 years. Statistically significant results were obtained in all cases, reflected by an improvement in VAS for neck/arm pain.

Conclusion:
MIS-CLF is an effective technique for treatment of radiculopathy due to cervical disc herniation in a carefully selected subgroup of patients with good medium- to long-term outcomes. A larger study would possibly highlight the effectiveness of this procedure.
Craniovertebral junction chordomas
Authors: Baldassarre Bianca Maria , Di Perna Giuseppe , Portonero Irene , Penner Federica , Cofano Fabio , Marco Raffaele De , Marengo Nicola , Garbossa Diego , Pecorari Giancarlo , Zenga Francesco 
Published: December 2021

Introduction:
Chordomas are rare and malignant primary bone tumors. Different strategies have been proposed for chordomas involving the craniovertebral junction (CVJ) compared to other locations. The impossibility to achieve en bloc excision, the impact on stability and the need for proper reconstruction make their surgical management challenging.

Objective:
The objective is to discuss surgical strategies in CVJ chordomas operated in a single-center during a 7 years' experience (2013-2019).

Methods:
Adult patients with CVJ chordoma were retrospectively analyzed. The clinical, radiological, pathological, and surgical data were discussed.

Results:
A total number of 8 patients was included (among a total number of 32 patients suffering from skull base chordoma). Seven patients underwent endoscopic endonasal approach (EEA), and posterior instrumentation was needed in three cases. Three explicative cases were reported: EEA for midline tumor involving lower clivus and upper cervical spine (case 1), EEA and complemental posterior approach for occurred occipitocervical instability (case 2), C2 chordoma which required aggressive bone removal and consequent implant positioning, focusing on surgical planning (timing and type of surgical stages, materials and customization of fixation system) (case 3).

Conclusion:
EEA could represent a safe route to avoid injuries to neurovascular structure in clival locations, while a combined approach could be considered when tumor spreads laterally. Tumor involvement or surgical procedures could give raise to CVJ instability with the need of complementary posterior instrumentation. Thus, a tailored preoperative planning should play a key role, especially when aggressive bone removal and implant positioning are needed.
Perbedaan Tekanan Darah Sebelum dan Sesudah Exercise Intradialysis Pada Pasien Hemodialisis di Unit Hemodialisis Rumah Sakit Panti Rahayu Gunung Kidul
Authors: Murni Yuliastuti Christina , Pujiastuti Th.Tatik , Suparmi, CB Sr. Lucilla 
Published: December 2021

ABSTRACT
Background:Hemodialysis defines as a process of cleaning the blood from waste substances through a filtering process outside the body. Patients with chronic renal failure undergoing hemodialysis often experience complications including hypotension. Several references state an alternative intervention to prevent complications of hypotension in hemodialysis patients with an Intradialytic exercise. Intradialytic exercise is a planned and gradual form of exercise that includes various stages of flexibility exercise, strengthening exercise and cardiovascular exercise performed during hemodialysis. Intradialytic exercise is aimed to improve the work of the heart, respiration and improve hemodialysis regulation for the better.
Objective:This study was aimed to determine the difference in blood pressure before and after intradialytic exercise in patients undergoing hemodialysis.
Methods:This research design used a quasi-experimental design with pre-test and post-test with control design. The samples were 38 respondents who taken by total sampling at the Hemodialysis Unit of Panti Rahayu Hospital. The samples were divided into the intervention group who undertook intradialytic exercise for 4 weeks, each respondent experiences twice a week, while the control group who did routine hemodialysis and independent exercise.
Results:The results showed that the distribution of the characteristics of the respondents was 51-54 years old (18.41%) the sex was mostly male (63.2%) Most of them (55.3%) underwent hemodialysis for less than 2 years. Statistically, it was known that there was no significant difference in blood pressure before and after intradialytic exercise inside patient’s body of the control and intervention groups. There was no significant difference in blood pressure between the intervention group compared to the control group, but there was a dynamic difference in blood pressure in patients who did intradialytic exercise.
Conclusion:There was dynamics of differences in blood pressure in patients undergoing intradialytic exercise, it is recommended that hemodialysis nurses at Panti Rahayu Hospital take care patients during hemodialysis so that these interventions are routinely carried out.
Study on probiotic as antibiotic replacement to improve egg production in commercial duck farms
Authors: Suswoyo Imam , Ismoyowati Ismoyowati , Tugiyanti Elly 
Published: December 2021

Abstract. A research has been conducted to study the potency of probiotics as antibiotic replacements in terms of egg production and income over feed cost at commercial duck farms. The treatments were control, probiotic administration (P1=5 and P2=7 ml/kg feed), and antibiotic administration (A1=0.5 and A2=1 dose). Thus, there were 5 treatment units which were replicated 4 times. Each unit had 30 laying ducks, so in total there were 600 local laying ducks. Parameters observed were egg production as Hen Day Production and egg mass. Hen Day Production was measured by calculating the number of eggs, divided by the number of female ducks in percentage. Egg mass was calculated by the number of eggs multiplied by the weight of the eggs, divided by the number of ducks. The results showed that egg production in control, P1, P2, A1 and A2 was 50.95%, 62.90%, 60.85%, 56.75% and 65.40% respectively. For egg mass, the data were 36.07+3.25; 44.58+3.63; 42.64+4.31; 41.44+3.76; and 45.27+4.57 respectively. Statistical analysis revealed that, for both parameters, there was a significant difference (P<0.05) between control and treatments but not a significant difference among treatment groups. It seemed that probiotics and antibiotics had similar effects on Hen Day Production and egg mass. It can be concluded that probiotics could replace antibiotic administration for laying ducks in terms of egg production.
Propuesta de parque biblioteca como potencializador y revitalizador de espacio público
Authors: Camacho Maurad Guissella Solange , Castillo Guamán Karla Gabriela , Coronel Poma María Soledad 
Published: December 2021

El espacio público es un eje transformador y revitalizador de ciudades que, además de embellecer el paisaje urbano, vincula las actividades culturales, sociales y económicas de la población. El propósito de este proyecto es diseñar una propuesta de un parque biblioteca con la finalidad de brindar a la comunidad un espacio cultural y social ubicado en el único lote vacío situado en el sector centro sur de la ciudad de Machala, en la provincia de El Oro al sur del Ecuador.
El proyecto se implanta en un espacio que, por su cercanía a la cárcel de la ciudad, ha sido abandonado en pleno seno urbano, y dificulta la conectividad de la ciudad. Con este, se propone crear una conexión tanto de los equipamientos aledaños como de la zona sur y este, y brindar espacios para diferentes actividades culturales y educativas a la comunidad.
Además, se propone aprovechar el reconocimiento que la ciudad de Machala ha adquirido a nivel nacional por contar con el árbol de Navidad más grande de Ecuador, y tomarlo como elemento fortalecedor del proyecto —ya que atrae la atención de turistas— para darle un lugar propio a este hito.
La propuesta va ligada a los resultados obtenidos por encuestas realizadas a la comunidad con el propósito de plantear espacios que sean apropiados para las necesidades del usuario.
Reliability and Performance Analysis of a Series-Parallel System Using Gumbel–Hougaard Family Copula
Authors: Maihulla Anas Sani , Yusuf Ibrahim , Bala Saminu I. 
Published: December 2021

This research looks into the reliability metrics that are used to assess the strength of a solar system’s serial system, which is made up of four subsystems. Each subsystem consists of two parallel active components: two out of two photo-voltaic panels, one of two charge controllers, two of two batteries, and one of two inverters. Both the charge controller and the inverter have two human operators or switches. The Gumbel–Hougaard copula family was used to produce formulations of system dependability metrics such as reliability, mean time to failure (MTTF), availability, and profit function. Numerical examples are presented to show the obtained results and to investigate the impact of various system characteristics. The new study might help homes overcome some of the problems experienced by electric generation systems operating in hostile locations or under adverse weather conditions. A new model was developed, and solar photovoltaic system’s subsystems were analyzed in order to identify the most essential component. It was also indicated how to improve the system.

Received: 8 August 2021 | Revised: 14 October 2021 | Accepted: 17 October 2021

Conflicts of Interest
The authors declare that they have no conflicts of interest to this work.
Relationship between Change Management and the Implementation of the Human Resource Information System in Isiolo County Government, Kenya
Authors: Dida Hadija Halake , Moguche Abel , Rintari Dr. Nancy 
Published: December 2021

Purpose: To establish the relationship between change management and the implementation of the human resource information system in Isiolo County Government, Kenya.
Methodology: This study was conducted in Isiolo County. Descriptive research design was used by the study to collect a total of 654 Employees of the county government of Isiolo who were the target population. The study employed stratified random sampling to select 30% of the employees in each stratum to obtain a sample of 196 employees of the county government. Data was collected using questionnaires. Data was then analyzed through SPSS version 23. The overall results were presented through inferential statistics such as regression, correlation and descriptive statistics frequencies and percentages. The data was presented using tables.
Results: The study found out that there is a relationship between change management and the implementation of the human resource information system in Isiolo County Government, Kenya. Change management had an R value of 0.791 and R square value of 0.627. This indicated that change management influenced 63% on implementation of HRIS. The other 37% remaining were determined by other factors. This indicated that change management was part of a key ingredient towards implementation of HRIS. It was found that change management had a relationship with implementation of HRIS.
Unique contribution to theory, policy and practice: The study concluded that even though change management was necessary to effectively implement HRIS some employees did not feel the need for change management. This was because the employees felt that they were okay with the current system and norms. The leadership did not articulately involve them in the vision attainment hence the main reason of employees not seeing the bigger picture. Therefore, the management should be more open minded and communicate frequently with the staff on where exactly the county was headed and what was needed to attain its vision and goals. Once the employees understand and internalize these things, it would motivate them to put effort so as to be part of realizing the vision.
Comparison between LDH with Zap-70 and CD38 as prognostic Markers in Chronic Lymphocytic Leukemia Sudanese patients - A Pilot Study in Khartoum State
Authors: Hassan Mohammed Yassmin , Hussein Elhassan Salma , Ibrahim Mariam Abbas , Mohammed Ali May , Eljaili Abubaker Nuha , A.Altayeb Osama , Abbass Karrar Eman 
Published: December 2021

Background: Several prognostic markers are used in clinical stages of Chronic Lymphocytic Leukemia (CLL); including lactate dehydrogenase enzyme (LDH), CD38 and Zeta associated protein kinase (ZAP70). This study aimed to compare LDH with ZAP70 and CD38 as prognostic markers in Sudanese patients with CLL.
Materials and Methods: Fifty newly diagnosed patients with CLL were enrolled in this cross-sectional study, the age of patients ranged between 36 - 85 years, with mean of 62 years. Of total patients; there were 34 males (68%) and 16 females (32%). Blood samples were obtained and LDH measurement was done by using Dirui CS-T240 automated analyzer while CD38 and ZAP-70 were measured by flowcytometry. Data were analyzed by statistical package for social science (SPSS) computer software program version 21. Results: The present study revealed a significant association between LDH and Rai staging (p. value= 0.002), when LDH compared with ZA-70 and CD38 as reference prognostic markers; poor correlation between CD38 and LDH was found (R2= 0.086, P value= 0.034) and no correlation between LDH level and ZAP-70 expression (R2= 000, P value= 0.960). In conclusion: According to the outcomes of this study; ZAP-70 and CD38 cannot be substituted by LDH as a prognostic marker.
YETİŞKİN BİREYLERİN ÖĞÜN TÜKETİM SIKLIĞI İLE ORTOREKSİYA NERVOZA EĞİLİMLERİNİN DEĞERLENDİRMESİ
Authors: OLCAY EMİNSOY İrem , EMİNSOY Gökhan 
Published: December 2021

Giriş: Ortoreksiya nervoza (ON), sağlıklı besinlerin tüketilmesine karşı patolojik bir saplantıdır. Kişinin amacı sağlığını korumaktır. Diğer yandan öğün tüketim sıklığı ve zamanlaması ile öğünler arasındaki sürenin de sağlıkla ilgili etkileri olduğu bilinmektedir.
Amaç: Bu çalışmada, ON eğilimi olan bireylerin öğün düzenlerinin nasıl olduğunun belirlenmesi ve öğün sıklığı ile ON arasındaki ilişkinin belirlenmesi amaçlanmıştır.
Yöntem: Google formlar ile 15 soruluk anket formu ile ORTO-11 ölçeğini içeren bir anket hazırlanmıştır. Anketin sosyal medya üzerinden, haberleşme grupları ve sosyal medya hesapları aracılığıyla dağılması ve uygulaması sağlanmıştır. Ankete Ocak - Nisan 2021 tarihleri arasında erişim sağlanmıştır. Elde edilen veriler SPSS 25 İstatistik paket programı kullanılarak uygun istatistiksel yöntemlerle değerlendirilmiştir.
Bulgular: Çalışmaya katılan bireylerin %87.1’i kadın, %12.9’u erkektir. Kadın ve erkeklerin yaş ortalaması sırası ile 29.2±11.90 ve 41.6±11.96 yıl, genel yaş ortalaması ise 30.8±12.55 yıldır. Kadınların sırası ile ağırlık, boy uzunluğu ve beden kütle indeksi (BKİ) ortalamaları 58.7±21.90 kg, 164.0±5.95 cm ve 21.9±5.07 kg/m2, erkeklerin sırası ile 94.6±15.71 kg, 176.8±5.91 cm ve 30.4±5.80 kg/m2’dir. Kadınların sırası ile ana öğün, ara öğün günlük öğün sayısı ile ORTA-11 puan ortalamaları 2.5±0.55, 1.7±0.99, 4.1±1.09 ve 25.8±4.17’dir, erkeklerin ise 2.6±0.50, 2.5±2.08, 4.8±1.20 ve 27.6±6.29 olarak belirlenmiştir. ORTO-11 puanları ile ağırlık, BKİ, ana öğün sayısı, ara öğün sayısı, toplam öğün sayısı arasında negatif yönlü ilişki, istatistikse olarak anlamlı değildir.
Sonuç: Bu çalışmada, ağırlık, BKİ, ana öğün, ara öğün, toplam öğün sayıları arasında istatistiksel olarak önemsiz olsa da, negatif bir ilişki bulunmuştur. Konu ile ilgili daha fazla çalışmaya ihtiyaç vardır.
Efektivitas Terapi Bekam pada Penderita Hipertensi: Studi Literatur
Authors: Zahara Syifa Annisa  , Rudiyanto Rudiyanto , Sholihin Sholihin 
Published: December 2021

Latar Belakang: : Hipertensi merupakan penyakit silent killer yang dapat terjadi tanpa gejala dan dapat menyebabkan komplikasi apabila tidak ditangani dengan cepat. Hipertensi dapat terjadi karena gaya hidup, obesitas, alkohol, merokok, stress, faktor usia, hingga faktor genetik. Pengobatan untuk hipertensi dapat dilakukan secara non-farmakologi yaitu dengan terapi bekam. Penelitian ini bertujuan mengetahui pengaruh terapi bekam pada penurunan tekanan darah pada penderita hipertensi.
Metode: : Pencarian Literature Review ini menggunakan analisis PICOT, dengan database Google Scholar, dan Garuda lalu dipilih artikel yang menggunakan metode quasy eksperimen serta artikel berbahasa indonesia dan bahasa inggris. Ditemukan 240 artikel, Selanjutnya di screening dan diambil artikel terbitan tahun 2015-2020 didapatkan 52 artikel. Berdasarkan jurnal akhir yang dianalisa sesuai kriteria inklusi dan ekslusi didapatkan 13 artikel. Kemudian di tinjau kembali berdasarkan artikel Nasional dan didapatkan hasil akhir 10 artikel yang ditelaah.
Hasil: Hasil literature review menunjukkan adanya pengaruh sebelum dan sesudah dilakukan terapi bekam. Hasil tekanan darah sebelum dilakukan terapi bekam berada dalam kategori hipertensi tingkat 1 (ringan) 60% dan hipertensi tingkat 2 (sedang) sebanyak 40%, setelah dilakukan terapi bekam berubah menjadi normal 20%, normal tinggi sebanyak 20%, dan hipertensi tingkat 1 (ringan) sebanyak 60% .
Kesimpulan: Pemberian terapi bekam sebagai salah satu terapi non-farmakologi mampu untuk diaplikasikan dalam menurunkan tekanan darah pada penderita hipertensi.