bluuebunny/crossref_metadata_2025_split huggingface dataset:
Deutsche Bahn: Entflechtung 2.0!
Authors: Kühling Jürgen , Gremm Cornelia 
Published: November 2021

ZusammenfassungDie Eisenbahninfrastruktur des DB Konzerns wird seit der Bahnreform 1994 zusammen mit den Eisenbahnverkehrsunternehmen in einer vertikal integrierten Konzernstruktur organisiert. Diese Konzernstruktur steht jedoch im Verdacht, Wettbewerbsverzerrungen auf der Ebene der Eisenbahnverkehrsunternehmen zu verursachen. Eine eigentumsrechtliche Trennung der Eisenbahninfrastruktur von dem restlichen Betrieb des DB Konzerns könnte diese Wettbewerbsverzerrungen unterbinden. Bisher fehlte hierfür jedoch die politische Mehrheit. Die Monopolkommission stellt in ihrem aktuellen Gutachten daher Maßnahmen vor, um im geltenden Rahmen die derzeitigen Unabhängigkeits- und Transparenzprobleme zu beheben.
Decolonising the Curriculum in International Law: Entrapments in Praxis and Critical Thought
Authors: al Attar Mohsen , Abdelkarim Shaimaa 
Published: November 2021

AbstractCalls to decolonise the curriculum gain traction across the academe. To a great extent, the movement echoes demands of the decolonisation era itself, a period from which academics draw both impetus and legitimacy. In this article, we examine the movement’s purchase when applied to the teaching of international law. We argue that the movement reinvigorates debates about the origins of international law, centring its violent foundations as well as its Eurocentric episteme. Yet, like many critical approaches toward international law, the movement is smitten with itself and with the regime. As a consequence, the outcome of its activism and critique is predetermined: both must redeem the Eurocentrism of international law and its associated pedagogy. Calls to decolonise the curriculum ultimately validate the epistemological limitations inherent to a stratified, international order, failing to offer a genuine alternative framework or epistemology.
Learning from Graduate and Undergraduate Public Health Virtual Internship Experiences with State Title V Agencies During COVID-19, Summer 2020
Authors: Handler Arden , Greenleaf Rebecca , Bozlak Christine T. , Moerchen Victoria , Pizur-Barnekow Kris , San Miguel Cindy , Sappenfield Olivia , Masini Gabriella 
Published: November 2021

Abstract
Background
Since summer 2014, the National MCH Workforce Development Center has placed students from MCH public health graduate (Centers of Excellence and Catalyst) and undergraduate (MCH Pipeline) programs, all funded by the Maternal and Child Health Bureau, in summer internships with state and territorial Title V agencies. In 2020, due to the COVID-19 pandemic the Title V MCH Internship Program was offered virtually.

Participants and Methods
This manuscript includes quantitative and qualitative data from 2017 to 2020 generated by both Title V MCH Internship student interns (n = 76) and their preceptors (n = 40) with a focus on a comparison between the 2020 virtual year and the 2017–2019 years.

Results
Evaluation data from the 2017 to 2020 Title V MCH Internship Program from both students and preceptors revealed the implementation of a robust and successful internship program in which students increased their confidence in a variety of team, mentorship, and leadership skills while gaining direct exposure to the daily work of state Title V agencies. However, students and preceptors identified more challenges during 2020 compared to previous years.

Conclusions
The COVID-19 Pandemic was both a disruption and a catalyst for change in education. While there were clearly some challenges with the pivot to a virtual Title V MCH Internship Program in summer 2020, students were able to participate in meaningful internship experiences. This success can be attributed to the ability of the internship sponsor to engage in best practices, including extensive planning and provision of ongoing support to the students. Going forward, it is recognized that virtual internships may facilitate access to agencies in distant locales, eliminating issues related to housing and transportation. When both virtual and in-person relationships are available, those responsible for internship programs, including the Title V MCH Internship, will need to weigh these type of benefits against the potential missed opportunities students may have when not able to participate in on-site experiences.
Synthetic OCT data in challenging conditions: three-dimensional OCT and presence of abnormalities
Authors: Danesh Hajar , Maghooli Keivan , Dehghani Alireza , Kafieh Rahele 
Published: November 2021

AbstractNowadays, retinal optical coherence tomography (OCT) plays an important role in ophthalmology and automatic analysis of the OCT is of real importance: image denoising facilitates a better diagnosis and image segmentation and classification are undeniably critical in treatment evaluation. Synthetic OCT was recently considered to provide a benchmark for quantitative comparison of automatic algorithms and to be utilized in the training stage of novel solutions based on deep learning. Due to complicated data structure in retinal OCTs, a limited number of delineated OCT datasets are already available in presence of abnormalities; furthermore, the intrinsic three-dimensional (3D) structure of OCT is ignored in many public 2D datasets. We propose a new synthetic method, applicable to 3D data and feasible in presence of abnormalities like diabetic macular edema (DME). In this method, a limited number of OCT data is used during the training step and the Active Shape Model is used to produce synthetic OCTs plus delineation of retinal boundaries and location of abnormalities. Statistical comparison of thickness maps showed that synthetic dataset can be used as a statistically acceptable representative of the original dataset (p > 0.05). Visual inspection of the synthesized vessels was also promising. Regarding the texture features of the synthesized datasets, Q-Q plots were used, and even in cases that the points have slightly digressed from the straight line, thep-values of the Kolmogorov–Smirnov test rejected the null hypothesis and showed the same distribution in texture features of the real and the synthetic data. The proposed algorithm provides a unique benchmark for comparison of OCT enhancement methods and a tailored augmentation method to overcome the limited number of OCTs in deep learning algorithms.Graphical abstract
Gliadin proteolytical resistant peptides: the interplay between structure and self-assembly in gluten-related disorders
Authors: Herrera Maria Georgina , Dodero Veronica Isabel 
Published: November 2021

Abstract
In recent years, the evaluation of the structural properties of food has become of crucial importance in the understanding of food-related disorders. One of the most exciting systems is gliadin, a protein in wheat gluten, that plays a protagonist role in gluten-related disorders with a worldwide prevalence of 5%, including autoimmune celiac disease (CeD) (1%) and non-celiac wheat sensitivity (0.5–13%). It is accepted that gliadin is not fully digested by humans, producing large peptides that reach the gut mucosa. The gliadin peptides cross the lamina propria eliciting different immune responses in susceptible patients. Many clinical and biomedical efforts aim to diagnose and understand gluten-related disorders; meanwhile, the early stages of the inflammatory events remain elusive. Interestingly, although the primary sequence of many gliadin peptides is well known, it was only recently revealed the self-assembly capability of two pathogenic gliadin fragments and their connection to the early stage of diseases. This review is dedicated to the most relevant biophysical characterization of the complex gliadin digest and the two most studied gliadin fragments, the immunodominant 33-mer peptide and the toxic p31-43 in connection with inflammation and innate immune response. Here, we want to emphasize that combining different biophysical methods with cellular and in vivo models is of key importance to get an integrative understanding of a complex biological problem, as discussed here.
When Minutes Matter: Rapid Infusion in Emergency Care
Authors: Piehl Mark , Park Chan W. 
Published: November 2021

AbstractPurpose of ReviewThis review provides historical context and an update on recent advancements in volume resuscitation for circulatory shock. Emergency department providers who manage critically ill patients with undifferentiated shock will benefit from the insights of early pioneers and an overview of newer techniques which can be used to optimize resuscitation in the first minutes of care.Recent FindingsRapid infusion of fluids and blood products can be a life-saving intervention in the management of circulatory and hemorrhagic shock. Recent controversy over the role of fluid resuscitation in sepsis and trauma management has obscured the importance of early and rapid infusion of sufficient volume to restore circulation and improve organ perfusion. Evidence from high-quality studies demonstrates that rapid and early resuscitation improves patient outcomes.SummaryCurrent practice standards, guidelines, and available literature support the rapid reversal of shock as a key priority in the treatment of hypotension from traumatic and non-traumatic conditions. An improved understanding of the physiologic rationale of rapid infusion and the timing, volume, and methods of fluid delivery will help clinicians improve care for critically ill patients presenting with shock.Clinical CaseA 23-year-old male presents to the emergency department (ED) after striking a tree while riding an all-terrain vehicle. On arrival at the scene, first responders found an unconscious patient with an open skull fracture and a Glasgow coma scale score of 3. Bag-valve-mask (BVM) ventilation was initiated, and a semi-rigid cervical collar was placed prior to transport to your ED for stabilization while awaiting air transport to the nearest trauma center. You are the attending emergency medicine physician at a community ED staffed by two attending physicians, two physicians assistants, and six nurses covering 22 beds. On ED arrival, the patient has no spontaneous respiratory effort, and vital signs are as follows: pulse of 140 bpm, blood pressure of 65/30 mmHg, and oxygen saturation 85% while receiving BVM ventilation with 100% oxygen. He is bleeding profusely through a gauze dressing applied to the exposed dura. The prehospital team was unable to establish intravenous access. What are the management priorities for this patient in shock, and how should his hypotension best be addressed?
Improved NSGA-III using transfer learning and centroid distance for dynamic multi-objective optimization
Authors: Zhang Haijuan , Wang Gai-Ge 
Published: November 2021

AbstractMulti-objective problems in real world are often contradictory and even change over time. As we know, how to find the changing Pareto front quickly and accurately is challenging during the process of solving dynamic multi-objective optimization problems (DMOPs). In addition, most solutions obey different distributions in decision space and the performance of NSGA-III when dealing with DMOPs should be further improved. In this paper, centroid distance is proposed and combined into NSGA-III with transfer learning together for DMOPs, called TC_NSGAIII. Centroid distance-based strategy is regarded as a prediction method to prevent some inappropriate individuals through measuring the distance of the population centroid and reference points. After the distance strategy, transfer learning is used for generating an initial population using the past experience. To verify the effectiveness of our proposed algorithm, NSGAIII, Tr_NSGAIII (NSGA-III combining with transfer learning only), Ce_NSGAIII (NSGA-III combining with centroid distance only), and TC_NSGAIII are compared. Seven state-of-the-art algorithms have been used for comparison on CEC 2015 benchmarks. Besides, transfer learning and centroid distance are regarded as a dynamic strategy, which is incorporated into three static algorithms, and the performance improvement is measured. What’s more, twelve benchmark functions from CEC 2015 and eight sets of parameters in each function are used in our experiments. The experimental results show that the performance of algorithms can be greatly improved through the proposed approach.
Gearless Track-Friendly Metro with Guided Independently Rotating Wheels
Authors: Megna Gianluca , Bracciali Andrea 
Published: November 2021

AbstractTrack–vehicle severe interaction on track with small curve radius results in rail wear and corrugation, and wheel polygonization, which drain considerable resources for rail grinding and wheels re-profiling in metro lines. To reduce the damage caused by track-vehicle severe interaction, the paper analyzes the reasons leading to rail wear and then proposes an architecture of a metro vehicle with independently rotating wheels driven directly by permanent magnet synchronous motors. The architecture is axle guidance, offered by passive linkages, which ensures that all axles are oriented radially, while control strategy was kept as simple as possible, identifying only two basic traction conditions. The concept is first discussed and then validated through a comprehensive set of running dynamics simulation performed with a multibody software to evaluate rail wear and rolling contact fatigue in traction/braking, coasting with different cant deficiency/excess conditions. The multibody dynamics simulation shows that the proposed architecture is virtually capable of avoiding both wear and rolling contact fatigue damages, and achieves the highest possible track friendliness. The concept of the proposed architecture is a track-fiendly metro architecture and could be a good reference for reducing rail-track interaction damages and maintainace cost.
Making Sense of Security
Authors: Heath J. Benton 
Published: November 2021

AbstractThis Article theorizes “security” as a site of continuing struggle in the international system between competing approaches to identifying and responding to urgent threats. Rather than endorsing a single approach, this Article argues that a claim to “security” can imply any one of four approaches to law and policy, each of which has radically divergent implications for who is empowered by a security claim and how that power interacts with existing legal rules. By moving among these four approaches, security claims can disrupt established systems of knowledge-production and redescribe the world in new ways.
An Assessment of Pediatric Resident Disaster Preparedness for the Neonatal Intensive Care Unit
Authors: Kuppanda Nitin , Simpson Joelle , Soghier Lamia 
Published: November 2021

Abstract

Objective:
To assess the level of neonatal intensive care unit (NICU) disaster preparedness among pediatric residents.

Methods:
A mixed-methods study including qualitative interviews and quantitative surveys was used. Interviews guided survey development. Surveys were distributed to residents who rotated through Children’s National NICU. Questions assessed residents’ background in disaster preparedness, disaster protocol knowledge, NICU preparedness, roles during surge and evacuation, and views on training and education.

Results:
Survey response was 62.5% (n = 80) with 51.3% of invited residents completing it. Pediatric residents (PGY-2 and PGY-3) (n = 41) had low levels of individual disaster preparedness, particularly evacuations (86%). None were aware of specific NICU disaster protocols. Patient acuity, role ambiguity, knowledge, and training deficits were major contributors to unpreparedness. Residents viewed their role as system facilitators (eg, performing duties assigned, recruiting other residents, and clerical work like documentation). Resident training requests included disaster preparedness training every NICU rotation (48%) using multidisciplinary simulations (66%), role definition (56%), and written protocols (50%). Despite their unpreparedness, residents (84%) were willing to respond.

Conclusion:
Pediatric residents lacked knowledge of NICU disaster response but were willing to respond to disasters. Training should include multi-disciplinary simulations that can be refined iteratively to clarify roles, and residents should be involved in planning and execution.
A new second-order upper bound for the ground state energy of dilute Bose gases
Authors: Basti Giulia , Cenatiempo Serena , Schlein Benjamin 
Published: November 2021

Abstract
We establish an upper bound for the ground state energy per unit volume of a dilute Bose gas in the thermodynamic limit, capturing the correct second-order term, as predicted by the Lee–Huang–Yang formula. This result was first established in [20] by H.-T. Yau and J. Yin. Our proof, which applies to repulsive and compactly supported

$V \in L^3 (\mathbb {R}^3)$

, gives better rates and, in our opinion, is substantially simpler.
Conditions for accretion disc formation and observability of wind-accreting X-ray binaries
Authors: Hirai Ryosuke , Mandel Ilya 
Published: November 2021

Abstract
We explore the effect of anisotropic wind driving on the properties of accretion onto black holes (BHs) in close binaries. We specifically focus on line-driven winds, which are common in high-mass X-ray binaries (HMXBs). In close binary systems, the tidal force from the companion star can modify the wind structure in two different ways. One is the reduction of wind terminal velocity due to the weaker effective surface gravity. The other is the reduction in mass flux due to gravity darkening (GD). We incorporate these effects into the so-called CAK theory in a simple way and investigate the wind flow around the accretor on the orbital scale. We find that a focused accretion stream is naturally formed when the Roche lobe filling factor is

${\gtrsim}0.8$

–0.9, analogous to that of wind Roche lobe overflow, but only when the velocity reduction is taken into account. The formation of a stream is necessary to bring in sufficient angular momentum to form an accretion disc around the BH. GD effects reduce the amount of accreted angular momentum, but not enough to prevent the formation of a disc. Based on these results, we expect there to be a discrete step in the observability of HMXBs depending on whether the donor Roche lobe filling factor is below or above

${\sim}$

0.8–0.9.
‘With sound of lute and pleasing words’: The Lute Song and Voice Types in Late Sixteenth- and Early Seventeenth-Century England
Authors: Robinson Richard 
Published: November 2021

AbstractThe Elizabethan and Jacobean lute song (1597–1622) represents one of the most iconic genres of all early music. Although much literature has been dedicated to this repertory, the issue of the voices for which this music was probably intended still remains surprisingly underexplored. This subject has, moreover, acquired greater significance in light of research undertaken by Simon Ravens (2014) and Andrew Parrott (2015), which has challenged the plausibility of the falsetto voice in Medieval and Renaissance Europe, particularly in sacred music.This paper explores the issue of the types of voices that most likely performed the Elizabethan and Jacobean lute song in three ways. Firstly, contemporary English evidence for lutes and viols is analyzed together with information regarding tuning and transposition. Secondly, the music itself is investigated, including the part names and clefs used alongside the tessitura of the melodic line. Finally, a detailed examination of evidence for the tenor and falsetto voice is presented, including a critical examination of the word ‘faine’ (usually assumed to mean ‘falsetto’). The collective results are then brought together to refine current ideas regarding the voices used in the Elizabethan and Jacobean lute song.
Civic Minstrels in Late Medieval England: New Light on Duties and Careers
Authors: Rastall Richard 
Published: November 2021

AbstractThe publications of the ongoing Records of Early English Drama project since 1979 have made available for the first time much early documentation about minstrels, including the civic minstrels or town waits. While this material leaves many questions unanswered, a more detailed picture of the early history of civic minstrels is emerging. This article focusses on three aspects of that history that have not previously been studied as such: the towns that employed civic minstrels by 1509, the minstrels’ possible special duties in ports, and their employment mobility.
Dietary calcium to phosphorus ratio affects postprandial phosphorus concentrations in feline plasma
Authors: Coltherd Jennifer Carolyn , Staunton Ruth , Colyer Alison , Gilham Matthew , Rawlings John , Alexander Janet E. , Logan Darren W. , Butterwick Richard , Watson Phillip , Bakke Anne Marie 
Published: November 2021

AbstractThe impact of dietary phosphorus on chronic renal disease in cats, humans and other species is receiving increasing attention. As Ca and P metabolism are linked, the ratio of Ca:P is an important factor for consideration when formulating diets for cats and other animals. Here, we describe a fully randomised crossover study including twenty-four healthy, neutered adult cats, investigating postprandial responses in plasma P, ionised Ca and parathyroid hormone (PTH) following one meal (50 % of individual metabolic energy requirement) of each of six experimental diets. Diets were formulated to provide P at either 0·75 or 1·5 g/1000 kcal (4184 kJ) from the soluble phosphorus salt sodium tripolyphosphate (STPP, Na5P3O10), variable levels of organic Ca and P sources, and an intended total Ca:P of about 1·0, 1·5 or 2·0. For each experimental diet, baseline fasted blood samples were collected prior to the meal, and serial blood samples collected hourly for 6 h thereafter. For all diets, a significant increase from baseline was observed at 120 min in plasma PTH (P < 0·001). The diet containing the highest STPP inclusion level and lowest Ca:P induced the highest peaks in postprandial plasma P and PTH levels (1·8 mmol/l and 27·2 pg/ml, respectively), and the longest duration of concentrations raised above baseline were observed at 3 h for P and 6 h for PTH. Data indicate that Ca:P modulates postprandial plasma P and PTH. Therefore, when formulating diets containing soluble P salts for cats, increasing the Ca:P ratio should be considered.