bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Trading Volume, Market Capitalization, Firm Size in explaining Return on Vultures
Authors: Hariyanto Dedi 
Published: April 2021

Purpose: The study aims to examine the effect of trading volume, market capitalization, and firm size in explaining return on vultures in selected companies in Indonesia.
Methodology/Approach/Design: The population is 131 JII forming companies in IDX between December 2009 – May 2010 to December 2019 – May 2020. All data is transformed into standard form because the model used is path analysis. The corresponding regression of equation 1 is the Random Effect model and the corresponding Regression equation 2 is the Fixed Effect model. This study uses panel data analysis; the Chow test and Hausman test are also used. Data is processed using statistics EViews software.
Results: The results of the equalization test 1, trading volume has a significant negative effect on the return of shares. The results also show that the market capitalization has a significant negative effect on the return of shares, and consequently the size of the company has a significant negative effect on the return of shares. Hasil testing for equalization 2, trading volume has a significant effect on vultures, while market capitalization has no significant effect on vultures. The size of the company has a significant effect on vultures, and the return of the company has a significant effect on vultures.
Practical Implications: This research is limited to the variety of indices and varieties of securities that become populations and samples. Future research can be developed by focusing on indices and securities as well as the development of other variables in the behavioral finance section in addition to herding.
Originality/Value: This study differs greatly from previous studies in emerging markets in contributing to literature from a new direction in exploring investor returns and herding.
Transferência tecnológica da vacina de influenza no acordo entre o Instituto Butantan e a Sanofis/Pasteur
Authors: Ibañez Nelson 
Published: April 2021

O presente artigo objetiva, passados mais de cem anos da pandemia de gripe espanhola (1918-1919), analisar o processo de transferência tecnológica da vacina de influenza da Sanofis Pasteur para o Instituto Butantan. A metodologia da pesquisa foi a de “estudo de caso” (YIN, 1994), respondendo às questões do “porquê” e do “como” ocorreu essa transferência. Analisa-se os contextos nacional e internacional no período, valendo-se de uma revisão bibliográfica do tema e realiza-se ainda análise documental e entrevistas semiestruturadas com atores-chave. As questões relativas ao “porquê” da transferência foram vistas de forma a identificar os aspectos envolvidos com a tomada de decisão, a relevância e a oportunidade de criação de conhecimento tecnológico por parte do setor público na produção em larga escala da vacina de influenza. As questões relativas ao “como”, ou seja, ao processo em si da transferência, objetivaram identificar e analisar: os instrumentos formais (contrato de transferência de tecnologia), as etapas de implementação, fatores intervenientes, relações entre parceira (Sanofis) e Instituto, entraves institucionais, impactos econômicos e por fim discutir os resultados e as possibilidades de inovação criadas por esse processo. Os resultados alcançados pela transferência trazem à tona uma série de situações positivas e possibilidades de ganhos com a produção local e seu potencial inovador, o que na área social se dá pelo custo-benefício do ponto de vista da economia devido ao impacto nas internações e medicamentos necessários para o tratamento das pessoas contaminadas pela gripe.
Endoscopy in a COVID-19 Referral National University Hospital: A Single-center Experience and Recommendations
Authors: Torres John Mark , Yasay Eric , Daez Ma. Lourdes , De Lusong Mark Anthony 
Published: April 2021

Rationale. COVID-19 pandemic disease, can be transmitted during gastrointestinal procedures, via aerosolized droplets, and via fecal shedding. Both international and local endoscopy societies have issued strategies to alleviate the risk to endoscopy personnel. However, several barriers against the implementation of these recommendations exist thus individual center’s policies are employed whenever applicable.
Objectives. This narrative study aims to describe the current experience and set-up in the endoscopy unit of a COVID referral center, discuss the stratification of patients for endoscopy, the operational management of the personnel and endoscopy unit in line with the adapted local and international guidelines and offer endoscopists a quick reference guide to adapt endoscopy practice during the pandemic in a resource-limited setting.
Methodology. This paper reviews and consolidates current endoscopy guidelines and describes the single-center experience of Philippine General Hospital.
Results. In resource-limited settings, with uncertainties of prolonged COVID-19 impact to healthcare, modification of practice, adherence to strategies and recommendations, empowerment of workforce, establishing the sustainability of resources, training, and service to patients, are essential components to combat current dilemma brought about by this pandemic.
Conclusion. Integration of current local and international guidelines encompass all aspects of endoscopy practice during the pandemic. The recommendations cited are aimed to guide other resource-limited endoscopy units for potential changes and guidance in the overall practice.
Treatment of Osteosarcoma Patients in the Philippine General Hospital during the COVID-19 Outbreak
Authors: Gaston Czar Louie , Yu Hazel Valerie , Dacanay Emileo , Dimayuga Cesar Cipriano , Estanislao Jochrys , Fajardo Pamela , Quintos Albert Jerome , Rubio Donnel Alexis , Wang Edward , Alcasabas Ana Patricia 
Published: April 2021

Objectives. The ongoing Coronavirus disease 2019 (COVID-19) pandemic has disrupted healthcare systems worldwide. This study aimed to document the effect of COVID-19 on osteosarcoma treatment pathways in the Philippine General Hospital (PGH) and determine if there were any delays.
Method. A retrospective review of osteosarcoma patients treated at the PGH from January 1, 2019 – January 1, 2020 (pre-COVID-19) was compared to those treated during the COVID-19 pandemic from March 1, 2020 – September 1, 2020. Rates of diagnosed osteosarcoma, admission for chemotherapy, admission for surgery, treatment abandonment, metastatic disease on presentation, 1-year mortality, and amputation were calculated and compared between the two groups.
Results. From March to September 2020, 11 newly diagnosed osteosarcoma patients sought consult at the PGH. Only one patient sought consult during the initial 3-4 months of the study, suggesting that patients delayed seeking healthcare during the period of enhanced community quarantine. Patients seen during the pandemic had a higher rate of metastatic disease on presentation, reflecting the delay in diagnosis. Due to COVID-19 restrictions early in the pandemic, osteosarcoma patients were coordinated and referred to outside hospitals for intravenous chemotherapy and surgery. Normalization of services (hospital admissions, limb salvage surgeries) were seen at the later stages of the study, corresponding to the loosening of the quarantine.
Conclusions. Osteosarcoma patients experienced delays in seeking consult, diagnosis, and treatment at the PGH due to the COVID-19 pandemic. Early indicators suggest worse outcomes for these patients due to the delays. Strategies employed during the pandemic, such as networking of care and telemedicine, may help in future outbreaks.
Message of the Philippine General Hospital Director
Authors: Legaspi Gerardo D. 
Published: April 2021

Sir Winston Churchill once said, “Never let a good crisis go to waste.” This was when, after the ravages of World War II, he sought to form the United Nations.
This pandemic has affected our daily lives in unimaginable ways, much like the World War did, almost 80 years ago. The onslaught of daily challenges required us to change our strategies, modify our course, and even abandon some plans. It did not, however, extinguish our quench for knowledge and the desire to share it with others.
I am truly proud of this COVID-19 special issue of Acta Medica Philippina, which stands as a testament to the unsinkable research spirit of the Philippine General Hospital (PGH) and the University of the Philippines as a whole. Ironically, it is in this unusual period that PGH has achieved its highest publication rate.
The vital lessons that the articles in this issue impart to its readers, culled from the seemingly desperate situation we are all in, would surely be instrumental for us to emerge out of this crisis better and wiser.

Gerardo D. Legaspi, MD Director Philippine General Hospital
Biometrics of fruits and seeds sold in open markets
Authors: CONCEIÇÃO Maria José Ferreira da , BARROS Rubens Pessoa de 
Published: April 2021

O Brasil encontra-se entre os três maiores produtores mundiais de frutas, estando no terceiro lugar no ranking mundial de produção. O país possui elevado consumo interno, e ainda exporta uma quantidade razoável, e desta forma a economia é influenciada diretamente pela fruticultura. Porém, algumas culturas enfrentam intempéries que afetam seu desenvolvimento e produtividade. Portanto, buscando oferecer produtos de qualidade, aumentar a produção e a lucratividade, os fruticultores buscam auxílio na ciência, a qual estuda novos métodos de manejo e melhoramento genético. Para dar suporte a estes estudos são necessários dados fornecidos pela biometria. Partindo dessa premissa, este estudo teve como objetivo analisar os dados da biometria de frutos comercializados em feiras livres do Agreste Alagoano para auxiliar como parâmetro da aquisição da compra. O delineamento experimental planejado foi o inteiramente casualizado, onde o pesquisador escolheu aleatoriamente as bancas de feiras e a coleta dos frutos. Os tratamentos se constituíram na coleta de dez espécies de frutos e as repetições cinco feiras semanais no período de outubro de 2019 a fevereiro de 2020. Os frutos foram estudados em triplicatas, utilizando-se uma amostra de dez unidades de cada espécie em cada feira visitada. Cada feira coletou-se três frutos das dez espécies comercializadas. As espécies de frutos foram: abacate, goiaba, laranja, limão, maçã, manga, mamão, maracujá, melão e pera. Para mensuração dos frutos utilizou-se paquímetro universal analógico da marca Amatools (150 mm/6”), com precisão de 0,05 mm e, para aferição dos pesos, balança semi-analítica. Os dados foram submetidos a análise de variância por comparação de médias múltiplas através das médias de Games-Howell a 5% de probabilidade. Para essa análise quantitativa da ANOVA e análise de regressão, utilizou-se o auxílio do programa estatístico AGROESTAT.
The impact of COVID-19 on cardiology departments
Authors: Ramphul Kamleshun , Lohana Petras , Verma Renuka , Sombans Shaheen 
Published: April 2021

The spread of the Coronavirus disease 2019 (COVID-19) pandemic throughout the world has persisted for over a year now [1]. Multiple hospitals in several countries do not have any free beds available and the health care providers are facing burn-out and fatigue. Some hospital centres such as in Lombardy, Italy even became an epicentre of infections [2]. We sought to briefly describe the changes seen and reported in literature by several cardiology departments from various regions across the world.
Lipotoxicity induced pancreatic beta cell damage is associated with GPR119/MST1/FoxO1 Pathway
Authors: Ma Lirong , Li Jianning , Song Hui , Li Yan , Wang Yue , Luan Yansong , Li Yuhan , Qi Hui , Yang Yi , Cai Lei 
Published: April 2021

IntroductionG-protein-coupled receptor 119 (GPR119) is emerging as a potential therapeutic target against type 2 diabetes with beneficial effects on glucose homeostasis. However, the function of GRP119 in lipotoxicity induced pancreatic beta cell apoptosis and the molecular mechanism remains largely unknown.Material and methodsImpact of GPR119 on pancreatic islet beta cell apoptosis was evaluated in INS-1 cells treated with palmitate. The subsequent modulation of the MST1-FOXO1-Pdx1 signaling pathway and pro-apoptotic caspase-3 system were determined by measuring the target protein and mRNA expression. Dyslipidemia mice with gain and loss of GPR119 function by the application of specific lenti-viral vector was utilized to evaluate the impact of GPR119 on pancreas function in vivo. Lipid metabolism, glucose and insulin response, morphological changes as well as activation/inhibition of MST1-FOXO1-Pdx1 signaling pathway in pancreas were analyzed systematically.ResultsPalmitate treatment stimulated pro-apoptotic response in INS-1 cells, accompanied by inhibition of GPR119 expression and the subsequent activation of the MST1-FOXO1 combined with inhibition of Pdx1 signaling cascade. Activation of GPR119 by MBX prevents INS-1 cell from lipotoxicity induced apoptosis by targeting the MST1-FOXO1-Pdx1 pathway. Moreover, overexpression of GPR119 significantly attenuates the dyslipidemia and dysfunction of the pancreas. In contrast, inactivation of GPR119 by lentiviral vector in mice results in accelerated pancreas apoptosis and malfunction. The protective effects of GRP119 on lipotoxicity induced pancreas dysfunction are associated with modulating the MST1-FOXO1-Pdx1 signaling cascade.ConclusionsGPR119 alleviates lipotoxicity induced pancreatic beta cell apoptosis and malfunction through regulating MST1-FOXO1-Pdx1 signaling pathway.
Qualitative and Quantitative Paradigm Constellation In Educational Research Methodology
Authors: Djafar Hilman , Yunus Rasid , DJ Pomalato Sarson W , Rasid Ruslan 
Published: April 2021

Differences qualitative and quantitative research to academicians and researchers mainly concentrated on education studies is only able to browse and identify with the fundamental difference merely as example: research that only uses quantitative data but using the qualitative as a benchmark often not considered as a quantitative research Likewise , qualitative research that uses quantitative data is not considered qualitative research. If traced further, actually qualitative and quantitative research very spacious and is a level. Qualitative and quantitative research in the context of methodology includes a researcher's conception of social reality, the researcher's self placement in relation to the reality study and various other reviews. Therefore, in this research article,is stated that the correlation between qualitative and quantitative research in educational research methodology is possible if both are based on the same paradigm. Conversely qualitative and quantitative researchis difficult to reconcile if they depart from different paradigms, which have different epistemological assumptions, and different goodness criteria.
ANALISIS PINALTI HUKUM MATI KEPADA PERANTARA JUAL BELI NARKOTIKA DAN PEMBELIAN KATEGORI TANAMAN NARKOTIKA (STUDI KASUS NO. 1991/PID.SUS/2019/PN MDN)
Authors: Sihotang Lesson , Butar-butar Gelora 
Published: April 2021

The problem of narcotics at this time has penetrated all elements of the nation, from children to adults, from the lower classes to officials, even law enforcers are not sterile from narcotics abuse. Its abuse is very dangerous to the future of the younger generation and threatens the existence of national security in a nation, so that it requires rules in the form of laws that regulate so as to reduce the number of abuse and distribution of narcotics. especially in Indonesia.
The problem in this writing leads to the basis for the judge's consideration in imposing capital punishment on intermediary actors of narcotics sale and purchase group 1 (one) not plants in Decision Number: 1991 / Pid.Sus / 2019 / PN Mdn.
Based on the results of the research and discussion carried out by the author in Decision Number: 1991 / Pid.Sus / 2019 / PN Mdn, the basis for the judge's consideration of imposing capital punishment on the intermediary narcotics buying and selling group I non-plant narcotics is based on judges' considerations juridically and non-juridically.considerations, Judicial namely valid evidence in the form of indictment, witness statements, evidence, documentary evidence, statement of the defendant revealed in court. The basis forconsiderations non-juridical consists of background actions, personal conditions, socio-economic conditions.
KAJIAN PENGARUH JUMLAH BIBIT PER LUBANG DAN JARAK TANAM TERHADAP PERTUMBUHAN DAN PRODUKSI PADI (Oryza sativa L.)
Authors: Amiroh Ana , Nazam Annisa Ullatifah , Suharso Suharso 
Published: April 2021

Tanaman padi (Oryza sativa L.) adalah tanaman pokok bagi warga negara Indonesia dimana tanaman ini merupakan tanaman pangan sehari-hari, oleh karena itu kebutuhan padi setiap tahunya meningkat. Di Indonesia kebutuhan tanaman padi semakin melonjak seiring dengan bertambah banyaknya jumlah penduduk. Menurut Anonimous, (2014). Penelitian ini dilaksanakan di desa Botoputih Kecamatan Tikung Kabupaten Lamongan, mulai bulan April sampai dengan bulan juni 2019. Penelitian ini menggunakan metode Rancangan Acak Kelompok (RAK) Faktorial dengan 2 faktor dan setiap faktor terdiri dari 3 level yaitu: faktor pertama yaitu banyak bibit per lubang yang terdiri dari 3 level yaitu 1 bibit/lubang, 2 bibit/lubang, dan 3 bibit/lubang tanaman. Faktor yang kedua yaitu: jarak tanam dengan 3 level yaitu, 20 x 20 cm, 20 x 25 cm, dan 20 x 30 cm. penelitian ini dilakukan bertujuan untuk mengetahui kajian pengaruh jumlah bibit per lubang dan jarak tanam terhadap pertumbuhan tanaman padi (Oryza sativa L.). hasil penelitian menunjukan bahwa terjadi interaksi antara jumlah bibit per lubang dan jarak tanam terhadap semua parameter perlakuan. Perlakuan ini menggunakan 1 bibit/lubang dengan jarak tanam 20 x 30 cm
APLIKASI PLANT GROWTH PROMOTING RHIZOBACTERIA (PGPR) TERHADAP INFEKSI Chrysanthemum mild mottle virus (CMMV), PERTUMBUHAN, DAN PRODUKSI TANAMAN KRISAN (Chrysanthemum sp.)
Authors: Choliq Fery Abdul , Martosudiro Mintarto , Jalaweni Safira Candra 
Published: April 2021

Krisan (Chrysanthemum sp.) adalah tanaman florikultura yang memiliki nilai ekonomi tinggi dan berpotensi besar untuk dikembangkan. Budidaya krisan tidak lepas dari kendala penyakit yang menyebabkan penurunan produksi salah satunya adalah serangan penyakit Chrysanthemum mild mottle virus (CMMV) yang menyebabkan gejala rusaknya bunga, tanaman kerdil, dan malformasi. Pengendalian CMMV masih menggunakan insektisida yang bertujuan untuk menekan populasi serangga vektor. Pengurangan penggunaan insektisida dapat menggunakan alternatif pengendalian yang lebih aman yaitu Plant Growth Promoting Rhizobacteria (PGPR). Bacillus subtilis, Pseudomonas fluorescens, dan Azotobacter sp. merupakan rizobakteri yang biasa digunakan sebagai PGPR karena memiliki peranan yang penting dalam mengendalikan serangan patogen dan bermanfaat untuk memacu pertumbuhan dan produksi tanaman. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh pemberian PGPR isolat B. subtilis, P. fluorescens, Azotobacter sp., dan kombinasinya terhadap serangan CMMV, pertumbuhan, dan produksi pada tanaman krisan.
Rancangan penelitian menggunakan Rancangan Acak Lengkap (RAL) 9 perlakuan. P0+: Kontrol positif (tanpa pemberian PGPR, dengan inokulasi virus); P0-: Kontrol negatif (tanpa pemberian PGPR, tanpa inokulasi virus); P1: Inokulasi virus + PGPR isolat B. subtilis; P2: Inokulasi virus + PGPR isolat P. fluorescens; P3: Inokulasi virus + PGPR isolat Azotobacter sp.; P4: Inokulasi virus + PGPR isolat B. subtilis + P. fluorescens; P5: Inokulasi virus + PGPR isolat B. subtilis + Azotobacter sp.; P6: Inokulasi virus + PGPR isolat P. fluorescens + Azotobacter; P7: Inokulasi virus + PGPR isolat P. fluorescens + B. subtilis + Azotobacter sp. Berdasarkan hasil penelitian, diketahui bahwa tanaman krisan yang diberi perlakuan PGPR tiga kombinasi yaitu P. fluorescens + B. subtilis + Azotobacter sp. menunjukkan hasil yang berbeda nyata dengan perlakuan yang lain. Setelah dikombinasikan, P. fluorescens + B. subtilis + Azotobacter sp. mampu memberikan hasil terbaik dalam hal menunda masa inkubasi CMMV, menekan intensitas serangan CMMV, serta meningkatkan pertumbuhan dan produksi tanaman krisan.
Efektivitas Macam Metode Aplikasi Pupuk Organik Cair dan Dosis Pupuk Kandang Ayam Terhadap Peningkatan Produksi Cabai Rawit (Capsicum frutescens L.)
Authors: Istiqomah Istiqomah , Anam Choirul , Zulkhilmi Faris 
Published: April 2021

Penelitian ini dilaksanakan di Desa Karang tawar, Kecamatan Laren, Kabupaten Lamongan. Ketinggian tempat ± 6 meter di atas permukaan laut (mdpl). Waktu penelitian dilaksanakan pada bulan Maret sampai Juni 2020. Penelitian ini menggunakan Metode Rancangan Acak Kelompok (RAK) yang disusun secara faktorial dengan dua faktor perlakuan yaitu Macam metode aplikasi POC Nasa (M) dan Dosis pupuk kandang ayam (D). Faktor Metode aplikasi terdiri 3 perlakuan yaitu: Tanpa aplikasi (MI), disemprot (M2), disiram (M3). Dosis Pupuk kandang Ayam terdiri dari 3 level yaitu: Pemberian 6 ton/ha (D1), Pemberian 10 ton/ha (D2), dan Pemberian 14 ton/ha (D3). Indikator pertumbuhan dan produksi yang diamati meliputi: Tinggi tanaman, Diameter batang, Jumlah Cabang, Banyak buah pertanaman dan Berat buah pertanaman. Pengamatan dilaksanakan mulai umur 14,28 hari dan dilanjut 42 hari sekali. Data hasil dari penelitian sejak tanaman berumur 14 hari hingga akhir pengamatan, dianalisa dengan analisa sidik ragam dan dilanjutkan dengan Uji BNT 5%. Hasil penelitian menunjukkan bahwa terdapat interaksi antara perlakuan macam metode aplikasi POC Nasa. Kombinasi perlakuan terbaik adalah D3M3 (pemberian pupuk 14 ton/ha) pada parameter tinggi tanaman dan Diameter batang. Perlakuan macam metode aplikasi POC Nasa hampir seluruh parameter pengamatan. Dosis pupuk kandang ayam berpengaruh terhadap tinggi tanaman, jumlah Buah, jumlah Cabang, banyak Buah dan Berat buah.
PENGARUH PEMANFAATAN KOPERASI TERHADAP TINGKAT KESEJAHTERAAN WARGA PADA KOPERASI SIMPAN PINJAM “KARYA AGUNG” BOJONEGORO
Authors: Kisno Saputra Rifky Ardhana 
Published: April 2021

Cooperative business entities have the main goal not to seek profit but to serve members of the cooperative to be more prosperous based on the principle of family. The savings and loan cooperative "Karya agung" collects funds from its members who then redistribute the funds to its members. This study aims to provide an overview of the effect of cooperative use on the level of welfare of citizens. The taking technique used in this research is random sampling technique. The method of data collection used is to use questionnaires, interviews and documentation. The analysis method uses correlation analysis techniques with the product moment. Calculation of the value of which states that there is an influence between the use of savings and loan cooperatives to the level of welfare of citizens.
PENGKODEAN DALAM PEMBELAJARAN PENULISAN SASTRA
Authors: Al farisi Tsalits Abdul Aziz 
Published: April 2021

The purpose of this research is to describe it 1) how is the coding system for creating poetry. 2) how can student understand objects in the ward then applied to the text of diction. 3) how can students create certain diction in relation to what one imagines. The methods in this research are using quantitatif methods with model design patterns using media as a basis for finding a purpose the study of literature at SMA Kanjeng Sepuh school X class. The result of this study is the observation table of assessments stuents interest in literature especially the poem. On other side of the observation of teacher and student activities carrying out the study of poetry is also a focus quantitatif data results. The conclusion of this study is to find a point of literary learning accuracy through quantitatif measures in coding systems. It needs to be used to find the concrete steps the literary writing learning pattern that currently is of little interest to students.