bluuebunny/crossref_metadata_2025_split huggingface dataset:
Early initial video-electro-encephalography combined with variant location predict prognosis of KCNQ2-related disorder
Authors: Xu Yan , Dou Ya-lan , Chen Xiang , Dong Xin-ran , Wang Xin-hua , Wu Bing-bing , Cheng Guo-qiang , Zhou Yuan-feng 
Published: October 2021

Abstract
Background
The clinical features of KCNQ2-related disorders range from benign familial neonatal seizures 1 to early infantile epileptic encephalopathy 7. The genotype-phenotypic association is difficult to establish.

Objective
To explore potential factors in neonatal period that can predict the prognosis of neonates with KCNQ2-related disorder.

Methods
Infants with KCNQ2-related disorder were retrospectively enrolled in our study in Children’s Hospital of Fudan University in China from Jan 2015 to Mar 2020. All infants were older than age of 12 months at time of follow-up, and assessed by Bayley Scales of Infant and Toddler Development-Third Edition (BSID-III) or Wechsler preschool and primary scale of intelligence-fourth edition (WPPSI-IV), then divided into three groups based on scores of BSID-III or WPPSI-IV: normal group, mild impairment group, encephalopathy group. We collected demographic variables, clinical characteristics, neuroimaging data. Considered variables include gender, gestational age, birth weight, age of the initial seizures, early interictal VEEG, variant location, delivery type. Variables predicting prognosis were identified using multivariate ordinal logistic regression analysis.

Results
A total of 52 infants were selected in this study. Early interictal video-electro-encephalography (VEEG) (β = 2.77, 1.20 to 4.34, P = 0.001), and variant location (β = 2.77, 0.03 to 5.5, P = 0.048) were independent risk factors for prognosis. The worse the early interictal VEEG, the worse the prognosis. Patients with variants located in the pore-lining domain or S4 segment are more likely to have a poor prognosis.

Conclusions
The integration of early initial VEEG and variant location can predict prognosis. An individual whose KCNQ2 variant located in voltage sensor, the pore domain, with worse early initial VEEG background, often had an adverse outcome.
Needs assessment for physical activity information during COVID-19 among a nationally representative sample of parents and children ages 6–17 in the United States: a cross-sectional study
Authors: Johnson Ashleigh M. , Kroshus Emily , Tandon Pooja S. 
Published: October 2021

Abstract
Background
The COVID-19 pandemic presented novel barriers to youth physical activity engagement. Identifying what resources parents and children are interested in receiving can support efforts to mitigate the negative impact of the pandemic on youth physical activity behavior. This study aimed to identify physical activity-related information needs during the COVID-19 pandemic among a nationally representative sample of American parents of children 6–10 years-old and parent-child dyads of children 11–17 years-old.

Methods
A cross-sectional survey was conducted by a market research company in October–November 2020. Parents and children were asked about their interest in specific types of information about helping their family and themselves, respectively, be active (Yes/No). Weighted percentages were calculated for reported information needs and compared using two-sample test of proportions.

Results
Final analytic sample was 1000 parents (55.4% female; 74.7% White; 74.0% non-Hispanic); 500 children 11–17 years-old (52.1% male; 77.6% White). Over 40% of participants were interested in information about being active during COVID-19. Parents were more likely to be interested in information if they always (versus never) worked from home [53.3% (95% CI: 43.3–63.0%) versus 22.0% (95% CI: 14.9–31.3%), p < 0.001]; had children attending school remotely versus in-person [47.3% (95% CI:40.2–54.5%) versus 27.5% (95% CI: 19.6–37.1%), p < 0.001]; and lived in a big city versus a rural area [66.5% (95% CI:54.5–76.7%) versus 34.1% (95% CI: 22.8–47.6%), p < 0.001]. Children most interested were those who did not have resources for online activity engagement and those worried about their safety or getting infected with COVID-19. Children were also more likely to be interested if their parents worked full-time versus not working [48.6% (95% CI:41.7–55.6%) versus 31.5% (95% CI: 24.1–39.9%), p < 0.001], and lived in a big city versus a rural area [57.2% (95% CI:45.3–68.3%) versus 27.8% (95% CI:17.8–40.7%), p < 0.001].

Conclusions
Families are interested in physical activity resources, particularly those whose daily routines and opportunities for physical activity may have been most significantly impacted by the pandemic. This includes parents who always worked from home or whose children attended school remotely. Identifying felt needs is an important step in developing tailored interventions that aim to effectively and sustainably support families in promoting physical activity.
Comparison of percutaneous transforaminal endoscopic decompression and short-segment fusion in the treatment of elderly degenerative lumbar scoliosis with spinal stenosis
Authors: Li Pengfei , Tong Yuexin , Chen Ying , Zhang Zhezhe , Song Youxin 
Published: October 2021

Abstract
Background
Degenerative lumbar scoliosis (DLS) combined with spinal stenosis is increasingly being diagnosed in the elderly. However, the appropriate surgical approach remains somewhat controversial. The aim of this study was to compare the results of percutaneous transforaminal endoscopic decompression (PTED) and short-segment fusion for the treatment of mild degenerative lumbar scoliosis combined with spinal stenosis in older adults over 60 years of age.

Methods
Of the 54 consecutive patients included, 30 were treated with PTED and 24 were treated with short-segment open fusion. All patients were followed up for at least 12 months (12–24 months). Patient demographics, and perioperative and clinical outcomes were recorded. Visual analog scale (VAS) scores, Oswestry disability index (ODI) scores, and modified Macnab criteria were used to assess clinical outcomes. At the same time, changes in disc height, segmental lordosis, coronal Cobb angle, and lumbar lordosis were compared.

Results
The mean age was 68.7 ± 6.5 years in the PTED group and 66.6 ± 5.1 years in the short-segment fusion group. At 1 year postoperatively, both groups showed significant improvement in VAS and ODI scores compared with preoperative scores (p < 0.05), with no statistically significant difference between groups. However, VAS-Back and ODI were lower in the PTED group at 1 week postoperatively (p < 0.05). According to the modified Macnab criteria, the excellent rates were 90.0 and 91.6% in the PTED and short-segment fusion groups, respectively. However, the PTED group had a significantly shorter operative time, blood loss, postoperative hospital stay, postoperative bed rest, and complication rate. There was no significant difference in radiological parameters between the two groups preoperatively. At the last follow-up, there were significant differences in disc height, segmental lordosis at the L4–5 and L5–S1 levels, and Cobb angle between the two groups.

Conclusion
Both PTED and short-segment fusion for mild degenerative lumbar scoliosis combined with spinal stenosis have shown good clinical results. PTED under local anesthesia may be an effective supplement to conventional fusion surgery in elderly patients with DLS combined with spinal stenosis.
The lost productivity cost of absenteeism due to COVID-19 in health care workers in Iran: a case study in the hospitals of Mashhad University of Medical Sciences
Authors: Faramarzi Ahmad , Javan-Noughabi Javad , Tabatabaee Seyed Saeed , Najafpoor Ali Asghar , Rezapour Aziz 
Published: October 2021

Abstract
Background
Human resources management plays an important role in social development and economic growth. Absence from work due to health problems can make obstacles to the growth of economy. This study conducted aimed to estimate the absenteeism costs of COVID-19 among the personnel of hospitals affiliated to Mashhad University of Medical Sciences in Mashhad, Iran.

Methods
This cross-sectional study was conducted between February 19, 2020, and September 21, 2020. The absenteeism costs were calculated using the human capital approach. Finally, we applied the linear regression to assess the impact of variables on the lost productivity of absenteeism due to COVID-19 among the personnel of hospitals affiliated to Mashhad University of Medical Sciences.

Results
The results of this study showed that 1958 personnel had COVID-19. The total of absenteeism days in our study were 32,209 days, with an average of 16.44 absenteeism days. Total costs due to absenteeism were estimated to be nearly $1.3 million, with an average of $671.4 per patient. The results of regression model showed that gender (male), age (> 50 years), employment Type (non-permanent) and monthly income had a positive relationship with the absenteeism cost. Also, there are a negative significant relationship between absenteeism cost with job (physicians) and work experience.

Conclusions
Absenteeism costs of COVID-19 in the hospitals of Mashhad University of Medical Sciences represent a significant economic burden. The findings of our study emphasize the emergency strategies to prevent and control COVID-19 among the healthcare workers. It can decrease the economic impacts of COVID-19 and improve human resources management during the COVID-19 pandemic.
Community-based rehabilitation implementation for people with disabilities in South Africa: a protocol for a scoping review
Authors: Blose Sithembiso , Cobbing Saul , Chetty Verusia 
Published: October 2021

Abstract
Background
People with disabilities (PWDs) remain among the poorest and least empowered population. They experience limited access to basic services, especially in low- and middle-income countries (LMIC). The infringement of their human rights remains at an alarming level, despite the availability of the community-based rehabilitation (CBR) strategy and the United Nations Convention on the Rights of People with Disabilities (UNCRPD). CBR, as a strategy for poverty alleviation, social inclusion and equalisation of opportunity, has broadened its scope from a mere strategy for access to health and rehabilitation services to include education, livelihood, social inclusivity and empowerment. CBR is implemented across the world in the majority of LMIC signatories to the UNCRPD. South Africa is among the countries that are implementing CBR. However, the extent and the nature of implementation is not known. This study, therefore, aims to map out the empirical evidence of the implementation of CBR in South Africa.

Method
The study is a scoping review based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extended for Scoping Review (PRISMA-ScR) methodology. The information will be extracted and captured on a data charting template that will be used through each phase of the study. The review will be guided by the following research question validated by the amended population-concept-context framework according to the Joanna Briggs Institute methodology for scoping reviews: ‘An investigation into CBR implementation in South Africa.’ The search will be conducted in the following electronic databases Google Scholar, PubMed, Medline, and Cochrane, etc, using Boolean logic. Restrictions will be set for years (Jan. 2009–Dec. 2019), English language peer-reviewed studies based on South Africa. The search output will be screened for primary studies on Community based rehabilitation in South Africa. Two independent reviewers will conduct title and abstract screening to identify potential eligible studies. After which full-text screening on the potential eligible studies and assessed for inclusion by the two independent reviewers. The Mixed Method Appraisal Tool will be applied to assess the quality of the studies included in the review.

Discussion
The gathered evidence from the selected studies will be discussed in relation to the research questions using a narrative to identify and explore emergent themes. The review will provide a baseline of evidence on the implementation of CBR and will highlight gaps regarding the implementation of CBR in a South African Context. The gaps identified will be used to develop a framework that will guide implementation of CBR in South Africa.
Taxonomic revision of the Savanna Nightjar (Caprimulgus affinis) complex based on vocalizations reveals three species
Authors: Sangster George , Cancino Kim Manzon , Hutchinson Robert O. 
Published: October 2021

AbstractBackgroundThe Savanna Nightjar (Caprimulgus affinis) is a widespread, polytypic species which was previously treated as two or three species. It is currently treated as a single species based on superficial similarity of their songs but no detailed comparisons of the songs in this complex have been made.MethodsA total of 15 acoustic variables were measured for the songs of 86 individuals representing 8 of the 10 subspecies in the complex.ResultsThree major groups can be distinguished based on univariate and multivariate analyses: a northern group consisting of the subspeciesC. a. monticolus,C. a. amoyensisandC. a. stictomus; a southern group consisting ofC. a. affinis,C. a. kasuidori,C. a. timorensisandC. a. propinquus; and a third group in the Philippines consisting ofC. a. griseatus.ConclusionsIt is here argued that these groups are best treated as species, and that Franklin’s Nightjar (C. monticolus) and Kayumanggi Nightjar (C. griseatus) are reinstated as separate species.
Exordium
Authors: Winter Enrique 
Published: October 2021

Abstract
As an introduction to Charles Bernstein's first poetry collection in Spanish, his translator traces a genealogy of linguistic procedures in American poetry and other theoretical and artistic sources relevant to the Language poets as well as to those influenced by them. This article offers a contextual and critical companion to each of Bernstein's publications throughout more than four decades. The special attention in the first half to a varying range of conceptual strategies in his books and rhetorical figures in his poems echoes in the arguments set in the second half for the selection and translation decisions made by the author in order to bring Bernstein's work into the Hispanic world.
This Working Title Will Be Replaced: Charles Bernstein's Forever Forthcoming
Authors: Stefans Brian Kim 
Published: October 2021

Abstract
Focusing on two key themes, or vectors, of Charles Bernstein's latest book of poetry, Topsy-Turvy, that of brokenness and the various references to “God” or religious belief, this review argues that there is a new metaphysical dimension in Bernstein's recent poetry that moves beyond his poetry's earlier emphases on the purely interpersonal and material nature of language and its uses. Through a discussion of Bernstein's concept of the never-attained “virtual” in his essay “Poetics of the Americas” and philosopher Gilles Deleuze's concept of the “virtual,” I argue that we can discern something like a “transcendental” aspect in Bernstein's poetry and philosophy, but not one that points to a God, a realm of ideals, or toward a telos, but something that exists now—a very real, but not yet actual, potential. As opposed to the merely “possible,” this potentiality allows for the truly novel to appear, either in poetry or the world itself.
Conservatism Gets Funded? A Field Experiment on the Role of Negative Information in Novel Project Evaluation
Authors: Lane Jacqueline N. , Teplitskiy Misha , Gray Gary , Ranu Hardeep , Menietti Michael , Guinan Eva C. , Lakhani Karim R. 
Published: October 2021

The evaluation and selection of novel projects lies at the heart of scientific and technological innovation, and yet there are persistent concerns about bias, such as conservatism. This paper investigates the role that the format of evaluation, specifically information sharing among expert evaluators, plays in generating conservative decisions. We executed two field experiments in two separate grant-funding opportunities at a leading research university, mobilizing 369 evaluators from seven universities to evaluate 97 projects, resulting in 761 proposal-evaluation pairs and more than $250,000 in awards. We exogenously varied the relative valence (positive and negative) of others’ scores and measured how exposures to higher and lower scores affect the focal evaluator’s propensity to change their initial score. We found causal evidence of a negativity bias, where evaluators lower their scores by more points after seeing scores more critical than their own rather than raise them after seeing more favorable scores. Qualitative coding of the evaluators’ justifications for score changes reveals that exposures to lower scores were associated with greater attention to uncovering weaknesses, whereas exposures to neutral or higher scores were associated with increased emphasis on nonevaluation criteria, such as confidence in one’s judgment. The greater power of negative information suggests that information sharing among expert evaluators can lead to more conservative allocation decisions that favor protecting against failure rather than maximizing success. This paper was accepted by Alfonso Gambardella, business strategy.
Comparison of Dielectric Properties of Traditional and High-Oleic Runner-Type Peanuts at Microwave Frequencies
Authors: Lewis Micah A. , Trabelsi Samir 
Published: October 2021

HighlightsPermittivity measurements were taken for traditional and high-oleic runner-type peanut pods and kernels at microwave frequencies.The dielectric constant, loss factor, loss tangent, and complex plane were compared between the two cultivars to observe any effect caused by the high-oleic trait.Despite differences in composition, minimal to no differences were observed in permittivity between the two cultivars.Abstract. Different cultivars of peanuts containing higher amounts of oleic acid have been developed to improve oxidative stability and overall peanut quality. Increasing oleic acid levels and decreasing linoleic acid levels in peanuts deter lipid oxidation, preventing the creation of off-flavors and increasing the shelf life. Since their conception, high-oleic peanuts have been tested from chemical and sensory perspectives to observe differences between them and traditional peanuts. Such tests have shown minimal differences, if any. However, tests to observe the effect of changing the levels of oleic and linoleic acid on permittivity, which is often used for nondestructive determination of the moisture content and bulk density of foods and agricultural products, have not been reported. Thus, a vector network analyzer (VNA) was used to take free-space transmission measurements of the complex permittivities of high-oleic and traditional runner-type peanut pods and kernels. Measurements were taken at 23°C between 5 and 9 GHz. Measurements yielded the dielectric constant and loss factor, which are often correlated to moisture content. Analysis was performed to compare the changes in the dielectric constant, loss factor, and loss tangent with moisture content for high-oleic and traditional peanuts. Linear trends were observed for each parameter with increasing moisture content for both cultivars. Results from the complex plane showed coefficient of determination (r2) values greater than 0.9 for pods and kernels. Therefore, at microwave frequencies, changing the levels of oleic and linoleic acid within the peanuts was observed to have minimal to no effect on their permittivity. Thus, moisture calibrations based on correlations between dielectric properties and moisture content for traditional runner-type peanuts can be applied to high-oleic cultivars. Keywords: Dielectric properties, Free-space transmission measurements, Microwave measurements, Oleic acid, Peanut kernels, Peanut pods.
Effect of Chloroplast Movement on Laser Speckle Method
Authors: Inagaki Yohsuke , Akune Rina , Matsuda Ayano , Kuroki Shinichiro , Takisawa Kenji , Fukushima Takashi 
Published: October 2021

HighlightsThis study investigates the use of laser speckle to evaluate chloroplast movement in plant cells.The analysis value of the laser speckle corresponds to chloroplast movement.The run-length matrix analysis that we propose is more sensitive than existing methods.Abstract. Abiotic and biotic stresses change the cytoplasmic streaming in plant cells. In particular, the state of chloroplast movement changes rapidly in response to environmental changes. Thus, detecting chloroplast movement allows us to comprehend the physiological state of plants. This study investigated the applicability of the laser speckle method for evaluating chloroplast movement. Moreover, we propose a new analysis method for sensitively evaluating chloroplast movement. Leaves of Egeria densa were used, and electrical stimulation was applied as recoverable abiotic stress. Laser speckle measurement and light microscopic observation of the same specimen were performed before and after stimulation. The results showed that the laser speckle method can nondestructively evaluate macroscopic and collective chloroplast movement. The proposed method was more sensitive to chloroplast movement than existing methods. Keywords: Chloroplast, Image processing, Laser speckle, Textual analysis.
The Second Heart Program—A multidisciplinary team supporting people who inject drugs with infective endocarditis: Protocol of a feasibility study
Authors: Lennox Robin , Lamarche Larkin , Martin Leslie , O’Shea Tim , Belley-Côté Emilie , Cvetkovic Anna , Virag Olivia , Whitlock Richard 
Published: October 2021

Introduction
Infective endocarditis (IE) is a severe and highly prevalent infection among people who inject drugs (PWID). While short-term (30-day) outcomes are similar between PWID and non-PWID, the long-term outcomes among PWID after IE are poor, with 1-year mortality rates in excess of 25%. Novel clinical interventions are needed to address the unique needs of PWID with IE, including increasing access to substance use treatment and addressing structural barriers and social determinants of health.

Methods and analysis
PWID with IE will be connected to a multidisciplinary team that will transition with them from hospital to the community. The six components of the Second Heart Team are: (1) peer support worker with lived experience, (2) systems navigator, (3) addiction medicine physician, (4) primary care physician, (5) infectious diseases specialist, (6) cardiovascular surgeon. A convergent mixed-methods study design will be used to test the feasibility of this intervention. We will concurrently collect quantitative and qualitative data and ‘mix’ at the interpretation stage of the study to answer our research questions.

Ethics and dissemination
This study has been approved by the Hamilton Integrated Research Ethics Board (Project No. 7012). Results will be presented at national and international conferences and submitted for publication in a scientific journal.

Clinical trail registrarion
Trial registration number: ISRCTN14968657 https://www.isrctn.com/ISRCTN14968657.