bluuebunny/crossref_metadata_2025_split huggingface dataset:
Good Practices of Comirnaty® Vaccine Injection Using Uncrimped Materials
Authors: Le Laetitia , Touchard Justine , Chastel Aymeric , Pineau Judith , Martelli Nicolas , Loustalot Marie-Caroline , Lebeaux David , Guerot Emmanuel , Prognon Patrice , Sabatier Brigitte , Caudron Eric 
Published: November 2021

Abstract
Background
In 2020, the first mRNA COVID vaccine was approved by the with six doses from single vial. In the context of material shortages, the aim of the study was to compare different protocols to extract doses using uncrimped materials with good trueness and reproducibility.
Methods
To optimize the extraction of the sixth dose from a single vial with uncrimped materials, alternative protocols of preparation were tested, derived from the drug information.
Results
The repeatability of injected volume was acceptable for all protocols (CV<5.3%). To prepare six 0.3mL doses using uncrimped materials, protocols with an air bubble were evaluated to offset the high dead volume inherent to uncrimped materials. Regarding the limited doses observed using long intramuscular needle (92.8% of the reference dose), the air bubble protocol with a liquid volume adjustment at 0.27mL was finally validated to respect the administration of full doses.
Conclusion
Results highlighted the necessity to adapt the drug information protocol for the preparation and administration of Cominarty®, due to the use of high dead volume materials. Despite the good reproducibility and accuracy of the air bubble protocols, some precautions have therefore to be taken to maintain the integrity of the vaccine suspension for efficient administration.
Peculiarities of surgical tactics of patients with thymus tumors
Authors: Ponomarova Kateryna 
Published: November 2021

The aim of the study: to study retrospective analysis results of the surgical treatment of thymus tumours for predicting long-time results.
Methods. Study included 35 patients who were treated at the Department of Thoraco-abdominal Surgery from September 2019 to May 2021. The control group included 20 patients with SVCS were treated with conventional techniques, while the experimental group included 15 patients who underwent a novel bypass surgery developed by us.
Results. The venous bypass was mandatorily complemented with cytoreduction. Complications in the post-operative period were reported from the experimental group and included auriculo-subclavian bypass thrombosis, post-operative complications were reported in the control group including haemorrhage from the sternotomy wound in 1 (3.3 %) case, superior vena cava thrombosis in 2 (6.6 %) cases, pneumonia in 2 (6.6 %). The relative risk of complications and lethal outcome was calculated for patients from both groups. It was found that the risk of complications was twice as high in the control group as in the experimental group (standard error of relative risk equals 0.64).
Conclusion. The first mandatory step of the radical surgery in patients with thymomas with SVC invasion should be the auriculo-jugular and auriculo-subclavian bypasses, which can reduce the relative risk of post-operative complications by a factor of the risk of lethal by a factor of 3.5
La necesidad de apoyo y la relación paterno- filial
Authors: Hurtado Rafael , Gotzón Santamaría Mikel 
Published: November 2021

En el presente artículo se explorará la necesidad imperante de todo ser humano por experimentar el amor de Dios a través del amor de su origen físico y espiritual, a saber, sus propios padres de familia. En la primera parte del análisis se desarrolla un breve marco teórico, partiendo de la experiencia de ser persona, que explica la relación entre la noción de amor y felicidad humanos. Posteriormente se establece la conexión indeleble entre la necesidad de experimentar el amor de Dios y corresponderlo, pasando por el reconocimiento excelso de la libertad. Amar y ser amado en la tierra, en ese sentido, pasa por el acto libre humano de aceptar la posibilidad de ser copartícipes de la procreación y educación de los hijos de Dios. Finalmente, se exalta el compromiso de toda sociedad por revalorar la función que ejercen los padres de familia en la construcción del “hogar global” de los seres humanos.
Abstract:
The following article will explore the human need to experience the love of God, through the love of those who are our physical and spiritual origin, that is, our parents. The first part of the analysis will stablish a theoretical framework, drawn from our human experience, that explains the relationship between the notion of human love and happiness. Secondly, the connection between the need to experience God’s love in order to reciprocate it through freedom will be brought to our discussion. In that sense, to love and being loved on earth becomes a matter of acknowledging the true nature of human freedom up to the point of, willingly, co-participating in God’s plan to become parents, that is: to procreate and educate the children of God. Finally, the commitment of every society to rethink and value the function of parents to build society from the inside, the “global home” for human beings, will be exalted.
Key Words: Love, Family, Parenthood, Freedom, Happiness.
La predestinación como teleología trascendente: Molina y el primer molinismo
Authors: Cruz Cruz Juan 
Published: November 2021

Este texto corresponde a una traducción de: Juan Cruz Cruz, “Predestination as trascendent teleology: Molina and the first Molinism”, en A companion to Luis de Molina (Brill, Leiden-Boston, 2014), 89-121.
This text corresponds to a translation of: Juan Cruz Cruz, "Predestination as transcendent teleology: Molina and the first Molinism", in A companion to Luis de Molina (Brill, Leiden-Boston, 2014), 89-121.
De camino hacia la Cruz. El recorrido de la iconografía proto cristiana
Authors: Zambruno Pablo 
Published: November 2021

El arte cristiano en general debe asumir el desafío de enseñar las profundidades de la fe, mediante un designio estético. En el Cristianismo de la Antigüedad, este proceso enfrentaba dificultades excepcionales: la convicción de vivir los últimos tiempos y la proscripción de las imágenes por parte del judaísmo; fueron necesarias nuevas generaciones que asumieran creativamente las “ultimidades” y que establecieron un fuerte nexo entre templo y comunidad. Luego debió asumir la Cruz, dolor y muerte, como emblema estético.
Abstract:
Christian art in general must take up the challenge of teaching the depths of faith through an aesthetic design. In the Christianity of Antiquity, this process faced exceptional difficulties: the conviction of living in the end times and the proscription of images by Judaism; new generations were needed to creatively assume the "ultimities" and establish a strong link between temple and community. Then it had to assume the Cross, pain and death, as an aesthetic emblem.
Key words:
Paleo-Christianity. Christ. Theological aesthetics. Truth. Cross.
Dynamic performance of engine timing transmission system with RU type synchronous belt
Authors: Hu Qingming , Hou Junpeng , Sun Dandan , Guo Jianhua 
Published: November 2021

The dynamic characteristic of the timing system has a significant impact on the performance of the engine's NVH. With low contact stress and strong anti-interference ability, the arc tooth synchronous belt was adopted by engine timing transmission system. The multi-body dynamics model of the in-line four cylinder engine timing system was established. We explored the influence of crankshaft speed and initial tension on the dynamic performance of the engine timing system. The result shows when the crankshaft speed V= 2000 r/min and the initial tension of the synchronous belt F= 300 N, the load distribution of the RU type synchronous belt teeth root is more uniform. The stress is 0.2474 N/mm2 lower than the average value, and the transverse vibration amplitude decreases by 0.3067 mm. Under this circumstance, the fluctuation amplitude of camshaft angular velocity is 6.5312 rad/s lower than the maximum average amplitude, so the transmission error is reduced by 37.95 %. The fluctuation amplitude of interference value decreases by 0.3413 mm, and the fluctuation amplitude of interference velocity decreases by 263.8908 mm/s. The synchronous belt based engine timing transmission is more stable and the dynamic performance is better. It laid a solid foundation for the optimization of the tooth profile and load conditions of the engine timing system.
Association of Serum Interleukin-34 and Insulin Resistance with Cognitive Impairment in Patients with Cerebral Small Vessel Disease
Authors: Jiang Tiantian , Zhou Yong , Zhang Dongmei , Cao Zhiyong , Bian Laifang , Ni Yi , Zhu Xiangyang 
Published: November 2021

Objective:
Insulin resistance (IR) is a key pathological process during the development
of cerebral small vessel disease (CSVD) and vascular cognitive impairment (VCI). The triglyceride-
glucose index (TyG index) is considered a novel marker of insulin resistance and can represent
peripheral tissue insulin sensitivity. Interleukin-34 (IL-34) is a cytokine of the short-chain helical
hematopoietic cytokine family and recent studies have shown that its serum levels may represent
an important biomarker for atherosclerosis. Here, we aimed to investigate whether the TyG index
and serum IL-34 levels were related to VCI in patients with CSVD.

Method:
This study included a total of 280 CSVD patients. TyG index, clinical baseline data, and
fasted venous blood for quantification serum levels of IL-34 were acquired within 24 hours of admission.
Multiple logistic regression analysis was applied to analyze the association between potential
risk factors and VCI, and receiver operator characteristic (ROC) curve was used to evaluate the
diagnostic value of IL-34, TyG index, and their combination for detecting VCI.

Results:
Among all included CSVD patients, 166 patients (59.3%) were diagnosed with VCI based
on the cognitive function scale (MOCA). After adjusting for confounding factors, serum IL-34 levels
and TyG index were independently associated with VCI (P<0.05). Using ROC curve analysis,
the optimal thresholds for identification of VCI based on serum IL-34 levels and TyG index were
41.57pg/ml (area under the curve (AUC): 0.723; sensitivity 76.5%; specificity 64%) and 3.94
(AUC:0.727; sensitivity 72.3%; specificity 62.3%), respectively.

Conclusion:
This study demonstrated that IL-34 and TyG index are closely associated with VCI in
CSVD patients and may represent clinical therapeutic targets for CSVD.
The Influence of Gender and Age on the Outcomes of and Adherence to a Digital Interdisciplinary Mental Health Promotion Intervention in an Australasian Nonclinical Setting: Cohort Study
Authors: Przybylko Geraldine , Morton Darren , Morton Jason , Renfrew Melanie 
Published: November 2021

Background
The global prevalence of mental health disorders is at a crisis point, particularly in the wake of COVID-19, prompting calls for the development of digital interdisciplinary mental health promotion interventions (MHPIs) for nonclinical cohorts. However, the influence of gender and age on the outcomes of and adherence to MHPIs is not well understood.

Objective
The aim of this study was to determine the influence of gender and age on the outcomes of and adherence to a 10-week digital interdisciplinary MHPI that integrates strategies from positive psychology and lifestyle medicine and utilizes persuasive systems design (PSD) principles in a nonclinical setting.

Methods
This study involved 488 participants who completed the digital interdisciplinary MHPI. Participants completed a pre and postintervention questionnaire that used: (1) the “mental health” and “vitality” subscales from the Short Form 36 (SF-36) Health Survey; (2) the Depression, Anxiety and Stress Scale (DASS-21); and (3) Satisfaction With Life Scale (SWL). Adherence to the digital interdisciplinary MHPI was measured by the number of educational videos the participants viewed and the extent to which they engaged in experiential challenge activities offered as part of the program.

Results
On average, the participants (N=488; mean age 47.1 years, SD 14.1; 77.5% women) demonstrated statistically significant improvements in all mental health and well-being outcome measures, and a significant gender and age interaction was observed. Women tended to experience greater improvements than men in the mental health and well-being measures, and older men experienced greater improvements than younger men in the mental health and vitality subscales. Multiple analysis of variance results of the adherence measures indicated a significant difference for age but not gender. No statistically significant interaction between gender and age was observed for adherence measures.

Conclusions
Digital interdisciplinary MHPIs that utilize PSD principles can improve the mental health and well-being of nonclinical cohorts, regardless of gender or age. Hence, there may be a benefit in utilizing PSD principles to develop universal MHPIs such as that employed in this study, which can be used across gender and age groups. Future research should examine which PSD principles optimize universal digital interdisciplinary MHPIs.

Trial Registration
Australian New Zealand Clinical Trials Registry ACTRN12619000993190; http://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=377889 and Australian New Zealand Clinical Trials Registry ACTRN12619001009101; http://www.anzctr.org.au/ACTRN12619001009101.aspx
MODERATION EFFECT OF MORAL OBLIGATION ON STUDENT’S INTENTION TOWARDS ACADEMIC DISHONEST BEHAVIOUR: THE CASE OF PUBLIC UNIVERSITIES IN GHANA
Authors: DZAKADZIE YAYRA 
Published: November 2021

The study examined the moderation effect of moral obligation on students’ intention towards academic dishonest behaviour. A survey-inferential design was used to randomly sample the views of 1,200 undergraduate university students. A structured questionnaire was used to collect. Structural Equation Modelling (SEM) and Conditional Process Analysis (CPA) were used for the analyses. Moral obligation statistically significantly moderated the intention to engage in academic dishonesty. It was concluded that an intention to engage in academic dishonesty decrease as moral obligation increases in the individual students. It was recommended that university authorities should introduce moral education as a core course among undergraduate students. This would instill in them a higher moral obligation in order to curb the academic dishonesty menace.
HUBUNGAN ANTARA KEHARMONISAN KELUARGA DENGAN KENAKALAN REMAJA SISWA SMK NASIONAL MOJOSARI
Authors: Ambara Ivania Christa 
Published: November 2021

AbstractThis study aims to determine whether there is a relationship between family harmony with juvenile delinquency at Mojosari National Vocational School. This study uses quantitative methods with research sampling techniques using probability sampling with disproportionate stratified random sampling method with an error rate of 5%. The total population in this study was 186 students and the number of samples in this study were 135 students of SMK Nasional Mojosari. The data collection tool was a questionnaire with a Likert scale on the variable family harmony and juvenile delinquency. Hypothesis testing using SPSS 20 for Windows with a correlation of r = - 0.516 with a significance of 0.000 (p <0.05) on the relationship between family harmony and juvenile delinquency in Mojosari National Vocational School students. So that there is a significant negative relationship between family harmony with juvenile delinquency at Mojosari National Vocational School. The hypothesis proposed in this study is accepted, meaning that the higher the family harmony, the lower the juvenile delinquency, and conversely the lower the family harmony, the higher the juvenile delinquency.AbstrakPenelitian ini bertujuan untuk mengetahui apakah terdapat hubungan antara keharmonisan keluarga dengan kenakalan remaja di SMK Nasional Mojosari. Penelitian ini menggunakan metode kuantitatif dengan teknik pengambilan sampel penelitian menggunakan probability sampling dengan metode disproportionate stratified random sampling dengan taraf kesalahan 5%. Jumlah populasi dalam penelitian ini adalah 186 siswa dan jumlah sampel pada penelitian ini adalah 135 siswa SMK Nasional Mojosari. Alat pengumpulan data berupa kuesioner dengan skala likert pada variabel keharmonisan keluarga dan kenakalan remaja. Uji hipotesis menggunakan SPSS 20 for Windows dengan korelasi r = - 0,516 dengan signifikansi 0,000 (p < 0,05) pada hubungan keharmonisan keluarga dengan kenakalan remaja pada siswa SMK Nasional Mojosari. Sehingga terdapat hubungan negatif yang signifikan antara keharmonisan keluarga dengan kenakalan remaja di SMK Nasional Mojosari. Hipotesis yang diajukan dalam penelitian ini diterima, artinya semakin tinggi keharmonisan keluarga maka semakin rendah kenakalan remaja, dan sebaliknya semakin rendah keharmonisan keluarga maka semakin tinggi kenakalan remaja.
PERBEDAAN CULTURE SHOCK DITINJAU DARI TIPE KEPRIBADIAN EXTROVERT DAN INTROVERT PADA MAHASISWA KARO UKSW ANGKATAN 2019 YANG BERASAL DARI SUMATERA UTARA
Authors: Manik Yessy Sepgina 
Published: November 2021

Mahasiswa yang memilih untuk melanjutkan pendidikan di luar dari daerah asalnya akan belajar untuk menyesuiakan diri dengan lingkungan yang baru, sehingga individu yang tidak mampu menyesuaikan diri akan merasakan culture shock. Tujuan penelitian ini adalah untuk mengetahui perbedaan culture shock yang ditinjau dari tipe kepribadian extrovert dan introvert pada mahasiswa, dengan hipotesis terdapat perbedaan antara individu extrovert dan introvert dalam menghadapi culture shock. Sampel penelitian berjumlah 50 orang mahasiswa Karo Universitas Kristen Satya Wacana yang berasal dari Sumatera Utara dan menggunakan teknik total sampling. Pengukuran penelitian ini menggunakan skala culture shock milik Mumford (1997) dengan (r = 0,822) dan skala kepribadian extrovert dan introvert milik Eyesenck yaitu Eyesenck Personality Questionnaire (EPQ) dengan r = (0,847). Analisis hipotesis menggunakan Mann Whitney U Test, yang menunjukkan hasil signifikan dengan p=0,000 (p<0,05). Dengan demikian, Individu dengan kepribadian extrovert akan memiliki tingkat culture shock yang lebih rendah, sedangkan individu dengan kepribadian introvert akan memiliki tingkat culture shock yang lebih tinggi.
Hubungan Antara Gratitude dengan Stres Kerja Pada Guru Sekolah Luar Biasa
Authors: Pramudani Zefanya Agatha 
Published: November 2021

Penelitian ini bertujuan untuk mengetahui hubungan gratitude dengan stres kerja pada guru sekolah luar biasa. Metode penelitian yang digunakan dalam penelitian ini adalah metode kuantitatif. Sampel dalam penelitian ini berjumlah 46 orang yang diambil menggunakan teknik quota sampling. Data penelitian diperoleh melalui wawancara dan kuesioner. Pengumpulan data variable gratitude menggunakan The Gratitude Questionnaires Six Item Form (GQ-6) oleh Michael E. McCullough, Robert A. Emmons, dan Jo-Ann Tsang (2002) yang terdiri dari 6 aitem, sementara variable stres kerja menggunakan Occupational Stress Indicator (OSI) oleh Cooper dan Williams (1988) yang terdiri dari 40 aitem. Analisis data menggunakan analisis korelasi. Hasil penelitian menunjukkan bahwa nilai r = -0,372 ; p > 0,05. Kesimpulan penelitian ini adalah gratitude berhubungan negatif terhadap variabel stres kerja. Kata Kunci: gratitude, stres kerja.
Hubungan antara harga diri dengan resiliensi pada perawat petugas Covid-19 di RS St. Elisabeth Semarang
Authors: Stevani Novia , Y. E. Kusumiati Ratriana 
Published: November 2021

Penelitian memiliki tujuan untuk mengetahui hubungan antara harga diri dengan resiliensi perawat petugas Covid-19 RSU St. Elisabeth Semarang. Jumlah partisipan yang berada di penelitian ini sebanyak 50 orang partisipan dengan teknik pengambilan data sampel jenuh. Data dianalisis menggunakan teknik korelasi Product Moment Pearson. Koefisien yang diperoleh sebesar 0,934 dengan signifikansi sebesar 0,000 (p < 0,05) sehingga bisa disimpulkan terdapat hubungan positif antara variabel harga diri dan resiliensi pada perawat petugas Covid-19 di RSU St. Elisabeth Semarang. Hipotesis yang diajukan dalam penelitian ini diterima, artinya semakin tinggi harga diri maka semakin tinggi resiliensi diri seorang perawat petugas Covid-19, dan sebaliknya semakin rendah harga diri maka semakin rendah resiliensi diri seorang perawat petugas Covid-19.
Analisis Tahapan dalam Belajar Konsep
Authors: Tarigan Noviani , Neviyarni Neviyarni 
Published: November 2021

Abstract: Concept learning refers to any activity in which learners must classify two or more somewhat different events or objects into one category, concept learning includes learning to make general responses to a group of stimuli that have some of the same features or properties. Concept refers to a set of features or attributes of one or more general properties connected by a rule. Learning concepts on the other hand includes learning a single response to two or more stimuli which is a comparison between stimulus and response. Concept learning requires that learners come to respond to features that are relevant to the concept and ignore features that are not relevant in classifying events. Indonesian Abstract: Pembelajaran konsep mengacu pada setiap aktivitas di mana peserta didik harus mengklasifikasikan dua atau lebih peristiwa atau objek yang agak berbeda ke dalam satu kategori, pembelajaran konsep mencakup pembelajaran untuk membuat tanggapan umum terhadap sekelompok rangsangan yang memiliki beberapa fitur atau sifat yang sama. Konsep mengacu pada sekumpulan fitur atau atribut dari satu atau lebih properti umum yang dihubungkan oleh suatu aturan. Konsep pembelajaran di sisi lain mencakup pembelajaran respons tunggal terhadap dua atau lebih rangsangan yang merupakan perbandingan antara rangsangan dan tanggapan. Pembelajaran konsep mengharuskan peserta didik datang untuk menanggapi fitur yang relevan dengan konsep dan mengabaikan fitur yang tidak relevan dalam mengklasifikasikan peristiwa.
Resiliensi dalam Badai: Belis dan Fenomena Kekerasan dalam Rumah Tangga di Kabupaten Alor
Authors: Lakamau Jean , Wibowo Doddy Hendro 
Published: November 2021

Abstract: Belis is a marriage tradition that is still a problem in the household. The men who have paid all the belis from the woman's side and made the women their wives, then they treat their wives when they go to the stage of violence. This study aims to determine the resilience of wives of victims of domestic violence due to belis and its impact on wives of victims of domestic violence. This study uses a qualitative research method with a phenomenological approach. The results of this study identified aspects of resilience, namely emotional regulation, impulse control, optimism, problem cause analysis, empathy, self-efficacy, and achievement. The three participants can overcome the problem of domestic violence they experience and are able to survive in situations such as receiving violence from their husband, and from the experiences they have experienced they can overcome problems in their household.Indonesian Abstract. Belis merupakan tradisi perkawinan yang masih menjadi masalah dalam rumah tangga. Para pria yang telah membayar semua belis dari pihak wanita dan menjadikan wanita sebagai istri mereka, kemudian mereka memperlakukan istri mereka ketika mereka menuju tahap kekerasan. Penelitian ini bertujuan untuk mengetahui ketahanan istri korban KDRT akibat belis dan dampaknya terhadap istri korban KDRT. Penelitian ini menggunakan metode penelitian kualitatif dengan pendekatan fenomenologi. Hasil penelitian mengidentifikasi aspek resiliensi yaitu regulasi emosi, pengendalian impuls, optimisme, analisis penyebab masalah, empati, efikasi diri, dan prestasi. Ketiga peserta dapat mengatasi masalah KDRT yang dialaminya dan mampu bertahan dalam situasi seperti menerima kekerasan dari suaminya, dan dari pengalaman yang dialaminya dapat mengatasi permasalahan dalam rumah tangganya.