bluuebunny/crossref_metadata_2025_split huggingface dataset:
Honey in wound healing: An updated review
Authors: Tashkandi Hanaa 
Published: October 2021

Abstract
Wound healing is a complex process with many interdependent pathophysiological and immunological mediators to restore the cellular integrity of damaged tissue. Cutaneous wound healing is the repair response to a multitude of pathologies induced by trauma, surgery, and burn leading to the restoration and functionality of the compromised cells. Many different methods have been employed to treat acute and chronic wounds, such as antimicrobial therapy, as most wounds are susceptible to infection from microbes and are difficult to treat. However, many antimicrobial agents have become ineffective in wound treatment due to the emergence of multiple drug-resistant bacteria, and failures in current wound treatment methods have been widely reported. For this reason, alternative therapies have been sought, one of which is the use of honey as a wound treatment agent. The use of honey has recently gained clinical popularity for possible use in wound treatment and regenerative medicine. With this high demand, a better delivery and application procedure is required, as well as research aiming at its bioactivity. Honey is a safe natural substance, effective in the inhibition of bacterial growth and the treatment of a broad range of wound types, including burns, scratches, diabetic boils (Skin abscesses associated with diabetic), malignancies, leprosy, fistulas, leg ulcers, traumatic boils, cervical and varicose ulcers, amputation, burst abdominal wounds, septic and surgical wounds, cracked nipples, and wounds in the abdominal wall. Honey comprises a wide variety of active compounds, including flavonoids, phenolic acid, organic acids, enzymes, and vitamins, that may act to improve the wound healing process. Tissue-engineered scaffolds have recently attracted a great deal of attention, and various scaffold fabrication techniques are being researched. Some incorporate honey to improve their delivery during wound treatment. Hence, the aim of this review is to summarize recent studies on the wound healing properties of honey.
Modulation of neo-endothelialization of vascular graft materials by silk fibroin
Authors: Zhan Congcong , Xia Chuanjun , Wang Pengfei , Ming Pingdeng , Zhang Shanfeng , Chen Junying , Huang Xia 
Published: October 2021

Abstract
Controlled neo-endothelialization is critical to the patency of vascular grafts. Expanded polyethylene terephthalate (PET) vascular grafts were grafted with polyethylene glycol (PEG), irradiated with ultraviolet light, and subsequently coated with silk fibroin (SF) and EDC in a dip-coating process. Endothelial cells were cultivated on the coated samples for 1, 3, 5, and 7 days, and characterized by fluorescence microscopy and scanning electron microscopy (SEM). The quantitative analyse of CCK-8 method was used to assess ECs proliferation. The results reveal the correlation between grafting components and cell adhesion. We demonstrated that PET with SF grafting facilitated cell adhesion and spreading. Following 7 days of cell culture in vitro, PET-PEG6000-SF (PEG molecular weight 6,000) displayed spreading of cells over a significantly larger area. Rapid endothelialization on a modified PET surface resulted in large tissue pack that can be observed by SEM.
Optimizing seaweed futures under climate change
Authors: Klinger Terrie 
Published: October 2021

Abstract
Seaweeds play essential ecological and biogeochemical roles and support important industrial applications. Sustaining natural populations of seaweeds under climate change while simultaneously putting seaweeds to use in climate solutions requires that we weave together disparate lines of inquiry—the ecological and the industrial—to create a more holistic perspective and integrated research agenda. Innovation in the use of seaweeds must be more than aspirational—it requires evidence of effectiveness in the short term, and a promise to sustain nature and people in the long term.
Locative phrase and descriptive discourse in L2 Chinese
Authors: Arslangul Arnaud , Watorek Marzena 
Published: October 2021

AbstractThis study examines the way in which French-speaking learners of L2 Chinese construct a type of discourse calledstatic spatial description. It involves the analysis of an oral corpus collected from two groups of native speakers of Chinese and French, and two groups of learners of L2 Chinese at two proficiency levels (low and intermediate). The data collected consist of the description of a poster. The results show that linguistic devices used in Chinese and French to encode the locative phrase and its syntactic functions have an impact on the presence and placement of the locative in utterances encoding spatial localization. These properties in turn influence the way in which the informational content develops across the utterances in the discourse. There is a clear development of proficiency between the two L2 groups. However, intermediate learners are not yet able to organize information on the discourse level like native Chinese speakers do.
Mapping the scientific research on the ionizing radiation impacts on polymers (1975–2019)
Authors: Girard-Perier Nina , Dorey Samuel , Marque Sylvain R. A. , Dupuy Nathalie 
Published: October 2021

Abstract
A bibliometric approach allowed us to study the global research trend on the impact of ionizing irradiations on polymers from 1975 to 2019. The investigation revealed 1,015 publications with growing interest since 1990. The research is split into three main categories: polymer science, nuclear science technology, and chemistry physical. The three main ionizing irradiations studied in this research are gamma, electron beam, and X-ray irradiations. The impact of ionizing irradiations on polymers under gamma irradiation is the most commonly studied field with 578 publications among the 1,015 publications. Electron beam irradiation is the second most studied field followed by X-ray irradiation. Whatever the irradiation modalities, publications focus on material degradation and material improvement studies.
Seshadri constants on some Quot schemes
Authors: Gangopadhyay Chandranandan , Hanumanthu Krishna , Sebastian Ronnie 
Published: October 2021

Abstract
Let E be a vector bundle of rank n on

ℙ
1

{\mathbb{P}^{1}}

.
Fix a positive integer d. Let

𝒬
⁢

(
E
,
d
)

{\mathcal{Q}(E,d)}

denote the Quot scheme
of torsion quotients of E of degree d and let

Gr
⁢

(
E
,
d
)

{\mathrm{Gr}(E,d)}

denote
the Grassmann bundle that parametrizes the d-dimensional quotients of the
fibers of E.
We compute Seshadri constants of ample line bundles
on

𝒬
⁢

(
E
,
d
)

{\mathcal{Q}(E,d)}

and

Gr
⁢

(
E
,
d
)

{\mathrm{Gr}(E,d)}

.
Absolute convergence factors of Lipschitz class functions for general Fourier series
Authors: Tsagareishvili Vakhtang , Tutberidze Giorgi 
Published: October 2021

Abstract
The main aim of this paper is to investigate the sequences of positive numbers, for which multiplication with Fourier coefficients of functions

f
∈

Lip
⁡
1

{f\in\operatorname{Lip}1}

class provides absolute convergence of Fourier series.
In particular, we found special conditions for the functions of orthonormal system (ONS), for which the above sequences are absolute convergence factors of Fourier series of functions of

Lip
⁡
1

{\operatorname{Lip}1}

class. It is established that the resulting conditions are best possible in certain sense.
Para toluenesulfonic acid-catalyzed one-pot, three-component synthesis of benzo[5,6]chromeno[3,2-c]quinoline compounds in aqueous medium
Authors: Orang Naser Sadeghpour , Soltani Hadi , Ghiamirad Mehdi , Sabegh Mehdi Ahmadi 
Published: October 2021

Abstract
A new series of benzo[5,6]chromeno[3,2-c]quinoline derivatives were successfully synthesized using various arylglyoxal monohydrates, quinoline-2,4-dione, and β-naphthol in H2O:EtOH (2:1) as a green solvent in the presence of catalytic amounts p-toluenesulfonic acid as a mild catalyst under reflux conditions with high yields (83–92%). The reaction conditions were optimized in different solvents at variable thermal conditions, and the optimized reaction condition for this synthesis has been reported. The structures of all new products were defined by 1H-NMR, 13C-NMR, FT-IR, mass spectral data, and HRMS.
Brothers in arms: proBDNF/BDNF and sAPPα/Aβ-signaling and their common interplay with ADAM10, TrkB, p75NTR, sortilin, and sorLA in the progression of Alzheimer’s disease
Authors: Eggert Simone , Kins Stefan , Endres Kristina , Brigadski Tanja 
Published: October 2021

Abstract
Brain-derived neurotrophic factor (BDNF) is an important modulator for a variety of functions in the central nervous system (CNS). A wealth of evidence, such as reduced mRNA and protein level in the brain, cerebrospinal fluid (CSF), and blood samples of Alzheimer’s disease (AD) patients implicates a crucial role of BDNF in the progression of this disease. Especially, processing and subcellular localization of BDNF and its receptors TrkB and p75 are critical determinants for survival and death in neuronal cells. Similarly, the amyloid precursor protein (APP), a key player in Alzheimer’s disease, and its cleavage fragments sAPPα and Aβ are known for their respective roles in neuroprotection and neuronal death. Common features of APP- and BDNF-signaling indicate a causal relationship in their mode of action. However, the interconnections of APP- and BDNF-signaling are not well understood. Therefore, we here discuss dimerization properties, localization, processing by α- and γ-secretase, relevance of the common interaction partners TrkB, p75, sorLA, and sortilin as well as shared signaling pathways of BDNF and sAPPα.
Study of catalytic hydrogenation performance for the Pd/CeO2 catalysts
Authors: Tang Congming , Zhao Yue , Li Tao , Liao Zhengjiang , Xu Benjing , Jiao Zhaojie , Zhou Guilin 
Published: October 2021

Abstract
Pd/CeO2 catalysts with different metallic Pd loading were synthesized by impregnation method. The physicochemical properties of prepared Pd/CeO2 catalysts and corresponding precursors were studied by XRD, XPS, H2-TPD and H2-TPR. Moreover, the catalytic performance of the Pd/CeO2 catalysts was investigated via gas phase benzene hydrogenation reaction at the temperature of 100–200 °C under atmosphere pressure. Results show that the catalytic performance of prepared Pd/CeO2 catalysts is directly related to the metallic Pd content. The amounts of active metallic Pd and adsorbed-desorbed hydrogen species on Pd/CeO2 catalysts increase with the increasing metallic Pd loading from 1.0 to 3.0%, while the numbers of them are slightly reduced on Pd/CeO2(3.5) catalyst. Furthermore, metallic Pd is highly dispersed on the nano-CeO2 supports, therefore, the prepared Pd/CeO2 catalysts present good gas phase benzene catalytic hydrogenation performance. At 200 °C, the benzene conversion over the Pd/CeO2 catalysts with different metallic Pd loading follows the rule: Pd/CeO2(3.0) > Pd/CeO2(3.5) > Pd/CeO2(2.5) > Pd/CeO2(2.0) > Pd/CeO2(1.5) > Pd/CeO2(1.0), corresponding values are 94.3, 96.4, 89.9, 82.8, 72.7, 42.6 and 94.3%. And the cyclohexane selectivity is 100% on all prepared Pd/CeO2 catalysts.
A mini-review of three-dimensional network topological structure nanocomposites: Preparation and mechanical properties
Authors: Liu Yusong , Huang Jichuan , Zhou Fan , Ni Lijuan , Shen Yingdong , Liu Weihua , Meng Fanbin 
Published: October 2021

AbstractThree-dimensional (3D) network topological structure composite (3D-NTSC) is a new type of composite in which both the matrix phase and the reinforced phase have 3D continuous network structure and interweave with each other. Different from fiber reinforcement and particle reinforcement, the reinforcing phase in the composite material runs through the whole matrix phase in a continuous form without destroying the topological continuity of the matrix phase, so that each matrix phase in the composite material can not only maintain its own excellent performance, but also can cooperate with each other and complement each other, so that the composite material can play a greater performance advantage. In recent years, 3D-NTSC has attracted the attention of researchers and has been widely used in practical production. At present, there are no comprehensive articles summarizing the research progress of this kind of materials. In this review, we discussed the recent progress of the preparation methods, including natural flow method, vacuum infiltration process, pressure filling method,in situfilling method, and co-building method. Furthermore, research progress on mechanical properties and some regular results, shortcomings, challenges, and prospects of 3D-NTSC were also put forward, which would be helpful to people working in the related fields.
A Multidisciplinary Approach to the Study of Early Neolithic Pyrotechnological Structures. The Case Study of Portonovo (Marche, Italy)
Authors: Barbaro Cecilia Conati , Forte Vanessa , Muntoni Italo Maria , Eramo Giacomo 
Published: October 2021

AbstractThe introduction of agricultural practices fostered the development of specific technologies for the new subsistence practices and the production of new artefacts. Pyrotechnological structures such as ovens are part of the Neolithic equipment and accompanied the spread of agriculture from the Near East across Europe and the Mediterranean Sea. Ovens located within settlements – mainly domed, above-ground structures – have been traditionally linked to cooking and baking. The function is usually deduced from techno-morphological traits, although experimental approaches or ethnoarchaeological observations have often been used. This article aims to demonstrate the effectiveness of the multidisciplinary approach to understand the function of fire structures. An integrated methodology that combines archaeological analysis, archaeometry, and experimental archaeology has been applied to study the underground ovens of the Early Neolithic site of Portonovo (Marche, Italy) dated to the sixth millennium BCE. Samples of hardened sediment of archaeological ovens’ inner surface and selected pottery fragments were analysed through X-ray powder diffraction to estimate the temperature reached. A life-size replica of an underground oven was then created to perform firing experiments, including pottery firing. Samples of the oven’s walls and experimental vessels were analysed with the same method, and the values were compared. Our results indicate that the Portonovo ovens are potentially multifunctional structures, built for about 700 years, always with the same technique exploiting the natural soil’s insulating properties.
Thermo-viscoelastic orthotropic constraint cylindrical cavity with variable thermal properties heated by laser pulse via the MGT thermoelasticity model
Authors: Abouelregal Ahmed Elsayed , Ahmad Hijaz , Yao Shao-Wen , Abu-Zinadah Hanaa 
Published: October 2021

Abstract
In the past few decades, many models have been proposed to address the shortcomings found in the classical theories of thermoelasticity and to allow limited speeds of heat waves. In this context, in the current paper a new generalized model of thermoelasticity based on the Moore–Gibson–Thompson (MGT) equation has been introduced. This new model can be derived by introducing the relaxation time factor into the third type of Green–Naghdi model (GN-III). In contrast to the previous works, it was taken into account that the physical properties of the material are dependent on temperature and on the viscous type. The viscoelastic medium has been assumed to obey the Kelvin–Voigt model. On the basis of the present model, thermo-viscoelastic interactions have been investigated in an unbounded orthotropic body with a cylindrical cavity. The surface of the cavity is restricted and exposed to a pulse-formed heat flow that dissolves exponentially. The characteristic thermal modulus of the material is assumed to be a linear function of temperature. The Laplace transform can be used to eliminate time dependency from control equations. Using a suitable approximate method, the transformed equations have been finally inverted by numerical inversion of the Laplace transform. Certain comparisons have been introduced to estimate the effects of the viscosity, pulsed heat, and thermal temperature-independent properties on all studied fields. A comparison with previous models of thermoelasticity is also performed in tables to verify the accuracy of the proposed model. We found from the results that the physical fields strongly depend on the viscoelastic parameter, the change of the thermal conductivity, and pulsed heat, so it is not possible to neglect their effect on the manufacturing process of machines and devices.
Solitary wave solutions of the ionic currents along microtubule dynamical equations via analytical mathematical method
Authors: Aljahdaly Noufe H. , Alyoubi Amjad F. , Seadawy Aly R. 
Published: October 2021

Abstract
In this article, a new generalized exponential rational function method (GERFM) is employed to extract new solitary wave solutions for the ionic currents along microtubules dynamical equations, which is very interested in nanobiosciences. In this article, the stability of the solutions is also studied. As a result, a variety of solitary waves are obtained with free parameters such as periodic wave solution and dark and bright solitary wave solutions. The solutions are plotted and used to describe physical phenomena of the problem. The work shows the power of GERFM. We found that the proposed method is reliable and effective and gives analytical and exact solutions.
Mehr Licht im Schatten? Neuere Ergebnisse über die Schattenwirtschaft
Authors: Schneider Friedrich 
Published: October 2021

ZusammenfassungIn diesem Überblicksartikel schätzt Friedrich Schneider mit Hilfe des MIMIC-Ansatzes („Multiple Indicators Multiple Causes“) Größe und Entwicklung der Schattenwirtschaft für 157 Länder in den Jahren 1991–2017 und stellt zugleich die einschlägige Literatur vor. Die OECD-Länder haben mit Werten unter 20 Prozent des offiziellen BIP die kleinste Schattenwirtschaft; die Länder in Lateinamerika und Subsahara-Afrika mit durchschnittlich fast 38 beziehungsweise 39 Prozent die größte. Der Durchschnitt über alle Länder liegt bei 30,9 Prozent. Die Schattenwirtschaft schrumpft dabei über die Zeit. Der durchschnittliche Rückgang beträgt 6,8 Prozentpunkte. Besonders groß ist die Schattenwirtschaft in Ländern wie Bolivien (Georgien) mit 62,9 (61,7) Prozent des BIP; besonders klein ist sie in Ländern wie der Schweiz (den Vereinigten Staaten) mit durchschnittlich 6,4 (7,6) Prozent. Zur Überprüfung der Robustheit werden die MIMIC-Ergebnisse mit denen des Diskrepanz-Ansatzes für 23 Länder verglichen. Für die meisten Länder zeigen sich stabile, ähnliche Ergebnisse. Abschließend wird die Interaktion der Schattenwirtschaft mit der offiziellen Wirtschaft untersucht. Erste Ergebnisse für Pakistan 1976–2015 zeigen kurzfristig einen negativen und langfristig einen positiven Effekt der Schattenwirtschaft auf das BIP.
Evaluating the power of the causal impact method in observational studies of HCV treatment as prevention
Authors: Samartsidis Pantelis , Martin Natasha N. , De Gruttola Victor , De Vocht Frank , Hutchinson Sharon , Lok Judith J. , Puenpatom Amy , Wang Rui , Hickman Matthew , De Angelis Daniela 
Published: October 2021

Abstract

Objectives
The causal impact method (CIM) was recently introduced for evaluation of binary interventions using observational time-series data. The CIM is appealing for practical use as it can adjust for temporal trends and account for the potential of unobserved confounding. However, the method was initially developed for applications involving large datasets and hence its potential in small epidemiological studies is still unclear. Further, the effects that measurement error can have on the performance of the CIM have not been studied yet. The objective of this work is to investigate both of these open problems.

Methods
Motivated by an existing dataset of HCV surveillance in the UK, we perform simulation experiments to investigate the effect of several characteristics of the data on the performance of the CIM. Further, we quantify the effects of measurement error on the performance of the CIM and extend the method to deal with this problem.

Results
We identify multiple characteristics of the data that affect the ability of the CIM to detect an intervention effect including the length of time-series, the variability of the outcome and the degree of correlation between the outcome of the treated unit and the outcomes of controls. We show that measurement error can introduce biases in the estimated intervention effects and heavily reduce the power of the CIM. Using an extended CIM, some of these adverse effects can be mitigated.

Conclusions
The CIM can provide satisfactory power in public health interventions. The method may provide misleading results in the presence of measurement error.
The functional kNN estimator of the conditional expectile: Uniform consistency in number of neighbors
Authors: Almanjahie Ibrahim M. , Bouzebda Salim , Chikr Elmezouar Zouaoui , Laksaci Ali 
Published: October 2021

Abstract
The main purpose of the present paper is to investigate the problem of the nonparametric estimation of the expectile regression
in which the response variable is scalar while the covariate is
a random function. More precisely, an estimator is constructed by using the k Nearest Neighbor procedures (kNN). The main contribution of this study is the establishment of the Uniform consistency in Number of Neighbors (UNN) of the constructed estimator. The usefulness of our result for the smoothing parameter automatic selection is discussed. Short simulation results show that the finite sample performance of the proposed estimator is satisfactory in moderate sample sizes.
We finally examine the implementation of this model in practice with a real data in financial risk analysis.
Engagement and constructiveness in online news comments in English and Russian
Authors: Trnavac Radoslava , Taboada Maite 
Published: October 2021

AbstractWe investigate the relationship between Engagement and constructiveness in online news comments by analyzing the frequency and type of Engagement expressions in a corpus of English and Russian comments, following the Appraisal framework. The comments in question, 10,000 words in each language, were posted in response to opinion articles in the Canadian newspaperThe Globe and Mailand the Russian online news channelRT. In the context of online news comments, users generally characterize constructive comments as posts that tend to create a civil dialogue through remarks that are relevant to the article and do not provoke an emotional response. Through quantitative and qualitative analyses, we conclude that the language of constructive comments is more explicitly subjective in both languages. The main difference in the use of Engagement expressions in constructive and non-constructive comments lies along the lines of certainty/uncertainty and reliability/unreliability. As for cross-linguistic differences, it seems that English constructive comments place emphasis on the reliability of a commenter’s knowledge, while Russian constructive comments employ more modals of necessity, which have a prescriptive function.