bluuebunny/crossref_metadata_2025_split huggingface dataset:
AKUT İSKEMİK İNME VE GEÇİCİ İSKEMİK ATAK GEÇİREN HASTALARDA MİZAÇ KİŞİLİK ÖZELLİKLERİ VE YAŞAM OLAYLARININ İNCELENMESİ
Authors: ŞAHİNER İsmail Volkan , AYTAÇ Emrah , ÜNAL Hanzade , YALÇIN ŞAHİNER Şafak , AKYÜZ Ayşegül , ÖZTÜRK Mehmet , YOLDAŞ Tahir 
Published: August 2021

Akut iskemik inme ve geçici iskemik atak geçiren hastalarda mizaç kişilik özellikleri ve yaşam olaylarının etkisi
ÖZET
AMAÇ: Akut iskemik inme ve geçici iskemik atak vasküler hasara bağlı olarak serebral kan akımının bozulması nedeniyle gelişir. İnme gelişiminde çeşitli genetik ve çevresel nedenler sorumlu olmakla birlikte çalışmalarda psikolojik faktörlerin de rol alabileceği saptanmıştır. Bu çalışmada kişilik özellikleri, mizaç ve geçirilmiş yaşam olaylarının inme ile ilişkili olup olmadığını saptamak amaçlanmıştır.
GEREÇ VE YÖNTEM: Çalışmaya NIH İnme Ölçeği puanı 10’nun altında olan, afazik olmayan, demans ve başka bilişsel bozukluğu olmayan 48 akut iskemik inme veya geçici iskemik atak geçiren hasta ile yaş ve cinsiyet uyumlu 47 gönüllü kontrol grubu dahil edilmiştir. Hasta ve kontrol grubuna sosyodemografik veri formu, Memphis, Pisa, Paris and San Diego Mizaç Değerlendirme Anketi, Mizaç ve Karakter Envanteri ve Yaşam Olayları Listesi uygulanmıştır.
BULGULAR: İnme hastaları ile kontrol grubunda yer alan sağlıklı bireyler arasında Memphis, Pisa, Paris and San Diego Mizaç Değerlendirme Anketinin depresif mizaç, irritabl mizaç ve anksiyöz mizaç alt ölçek puanları açısından istatistiksel olarak anlamlı fark saptanmıştır. Çalışma grupları arasında Yaşam Olayları Listesi ölçeğinin distres ve uyum alt ölçek puanları açısından istatistiksel olarak anlamlı bir fark saptanmamıştır. Mizaç Karakter Envanteri ise her iki grup arasında yenilik arayışı, zarardan kaçınma, sebat etme, kendi kendini yönetme ve iş birliği puanları açısından anlamlı farklılıklar saptanmıştır.
SONUÇ: İnme hastalarının depresyona eğilimli mizaç ve karakter özelliklerine sahip olduğunu tespit edilmiştir. Bu çalışma, ülkemizde inme geçiren hastaların mizaç ve karakter özellikleri ve yaşam olayları karşında verdikleri distres ve uyumu değerlendiren ilk çalışmadır.

Anahtar sözcükler: İskemik inme, kişilik, yaşam olayları
Maküler Kornea Distrofisinde Korneanın Biyomekanik Özellikleri
Authors: UZMAN Selma , DEMİROK Gülizar , YALNIZ-AKKAYA Zuleyha , EKSİOGLU Umit , ŞİNGAR Evin , YAKIN Mehmet , ORNEK Firdevs , BURCU Ayşe 
Published: August 2021

Amaç: Maküler kornea distrofisinin (MKD) korneanın biyomekanik özellikleri üzerindeki etkisinin değerlendirilmesi ve sağlıklı bireyler ile karşılaştırılması amaçlandı.
Gereç ve Yöntem: Klinik olarak MKD tanısı konulmuş 45 hastanın 45 gözü (MKD grubu) ve 61 sağlıklı bireyin 61 gözü (kontrol grubu) çalışma kapsamına alındı. Tam oftalmolojik muayene sonrasında oküler cevap analizörü (ORA) ile, kornea histerezisi (KH), kornea direnç faktörü (KRF), Goldmann ile uyumlu göz içi basıncı (GİBg) ve kornea düzeltmeli GİB (GİBcc) değerleri ve Pentacam veya ultrason pakimetrisi ile merkezi kornea kalınlığı (MKK) ölçüldü ve kaydedildi.
Bulgular: İki grup, ortalama yaş (37,49 ± 10,05 ve 36,70 ± 10,72 yıl, p=0,703) ve cinsiyet dağılımı açısından (p=0,976) benzerdi. Maküler kornea distrofisi grubu ve kontrol grubunda ortalama KH [9,52 ± 1,37 ve 10,99 ± 1,16 mmHg (p
ANALISIS PEMAHAMAN DEMOKRASI MAHASISWA TEKNIK LISTRIK MENGGUNAKAN PEMANFAATAN MEDIA SOSIAL
Authors: Hiliadi Wardiani , Graha Setia , Saputra Rully Rezki 
Published: August 2021

Tujuan dari penelitian ini adalah untuk menganalisa tingkat pemahamana berdemokrasi mahasiswa Teknik Listrik menggunakan pemanfaatan media sosial. Sampel yang digunakan adalah 45 orang dari 90 populasi yang ada. Metode penelitian yang digunakan adalah mixed method, yang merupakan kombinasi metode penelitian kuantitatif dan kualitatif. Hasilnya menunjukkan pada beberapa indicator berdemokrasi menunjukkan memahami betul konsep berdemokrasi khususnya di era digital. Seperti tingkat pemahaman 1). Toleransi: status Sangat baik dengan persentase 79% 2) Kebebasan mengemukakan pendapat: status Sangat Baik dengan persentase 80% 3. Terbuka dalam berkomunikasi: Baik dengan persentase 62,25% 4) Menjunjung tinggi nilai dan martabat kemanusiaan: Cukup Baik dengan persentase 59,5%. 5. Mampu mengekang diri atas ego sendiri:Cukup Baik dengan presentase 60%. 6) Menghormati perbedaan pendapat: Sangat Baik dengan persentase 80%. . Penelitian ini hanya sebagai awalan untuk nantinya bisa di kembangakan lagi dengan konten yang lebih luas seperti pemahaman politik ataupun sosial budaya pada mashasiswa dengan pemanfaatan media sosial seperti Instagram ataupun Twitter serta berbagai media yang memungkinkan untuk dijadikan sebagai instrumen dalam sebuah penelitian sejenis.
ANALYSIS OF PROTECTIVE GAS FLOW AND SEAM FORMATION ON GMAW WELD PROCESS TO HARDNESS AND MICRO STRUCTURE OF ASTM A36 STEEL
Authors: Lambang Fius , Tamjidillah Mastiadi 
Published: August 2021

Penelitian ini bertujuan untuk mengetahui pengaruh variasi aliran gas pelindung dan bentuk kampuh terhadap kekerasan dan struktur mikro baja ASTM A36. Variasi aliran gas pelindung yang digunakan adalah 5 liter/menit, 10 liter/menit dan 15 liter/menit, sedangkan bentuk kampuh yang digunakan adalah kampuh I, ½ V dan V dengan elektroda ER 70S-6 diameter 1,2 mm. Hasil penelitian menunjukkan bahwa aliran gas pelindung yang semakin besar akan meningkatkan nilai kekerasan. Peningkatan nilai kekerasan weld metal dan HAZ tertinggi ada pada kampuh V dengan aliran gas 15 liter/menit sebanyak 38,06% weld metal, 11,15% HAZ, sedangkan nilai kekerasan terendah weld metal terdapat pada aliran gas 5 liter/menit pada kampuh ½ V yaitu 41,9 HRB dan nilai kekerasan HAZ terendah terdapat pada aliran gas 5 liter/menit pada kampuh I yaitu 40,8 HRB. Peningkatan nilai kekerasan base metal tertinggi ada pada kampuh ½ V sebanyak 39,46% dengan aliran gas 15 liter/menit sedangkan kekerasan base metal terendah pada kampuh I yaitu 43,4 HRB dengan aliran gas 5 liter/menit. Hasil pengujian struktur menunjukkan semakin tinggi aliran gas pelindung akan meningkatkan pembentukkan pearlite lebih banyak. Persentase pembentukan pearlite paling banyak ada pada weld metal kampuh V yaitu 53,16% dan persentase pearlite paling sedikit daerah HAZ kampuh I yaitu 38,17%.
ANALYSIS OF VARIATION OF WIRE FEEDER SPEED ON GMAW WELD PROCESS AGAINST MICRO AND STRUCTURE VIOLENCE ASTM STEEL A36
Authors: M.Ngari.SR. Aditya Nur Ramadhan , Tamjidillah Mastiadi 
Published: August 2021

Penelitian ini bertujuan untuk mengetahui pengaruh variasi kecepatan wire feeder pada proses las GMAW terhadap kekerasan dan struktur mikro baja ASTM A36. Variasi wire feeder yang digunakan adalah 3,5 meter/menit, 3,55 meter/menit dan 3,6 meter/menit, elektroda ER 70S-6 diameter 1,2 mm. Hasil penelitian menunjukkan bahwa nilai kekerasan tertinggi pada weld metal terdapat pada spesimen 1 kecepatan wire feeder 3,5 meter/menit dengan nilai kekerasan 59,5 HRB. Nilai kekerasan tertinggi pada daerah HAZ terdapat pada spesimen 3 dengan kecepatan wire feeder 3,6 meter/menit dengan nilai kekerasan 57,5 HRB. Sedangkan nilai kekerasan base metal tertinggi terdapat pada spesimen 3 kecepatan wire feeder 3,55 meter/menit dengan nilai kekerasan 64,4 HRB. Hasil pengamatan struktur mikro menunjukan bahwa semakin tinggi nilai kekerasan akan meningkatkan fasa pearlite lebih banyak dan sebaliknya semakin rendah nilai kekerasan maka fasa ferrite lebih banyak dibandingkan dengan fasa pearlite.
ENERGY AND PROTEIN INGREDIENTS FOR USE IN PIAPARA (<i>Megaleporinus obtusidens</i>) DIETS: NUTRITIVE VALUE AND INTESTINAL MORPHOMETRY
Authors: TANAKA Renata Akemi , ALMEIDA Viviane do Nascimento Santana de , FARIAS Carolina Vasconcelos Tavares de , SOUSA Luana Camargo , CARLI Gabriela Castellani , MANSANO Cleber Fernando Menegasso , TAKAHASHI Leonardo Susumu 
Published: August 2021

The apparent digestibility coefficients for crude protein (ADCCP), dry matter (ADCDM), and gross energy (ADCGE) of ingredients were determined for piapara (Megaleporinus obtusidens). Test diets were formulated to contain 69.5% of reference diet, 0.5% of chromium oxide, and 30% of test ingredients. The protein ingredients evaluated were tilapia processing residue meal (TPRM), feather and poultry blood meal (FPBM), poultry by-product meal (PBM), meat and bone meal (MBM), cottonseed meal (CM), corn gluten meal (CGM), and soybean meal (SM); the energy ingredients tested were corn (C), corn germ meal (CGRM), rice meal (RM), wheat bran (WB), and sorghum (S). Groups of 30 piaparas were fed twice daily during five days with test diets. Intestinal morphometry of fish were also evaluated. Digestibility coefficients of protein and energy ingredients were highest for soybean meal (ADCDM = 85.8%; ADCCP = 95.2%; and ADCGE = 87.2%) and corn (ADCDM = 94.5%; ADCCP = 76.2%; and ADCGE = 89.3%), respectively. Of the energy test ingredients analyzed, corn had the highest digestibility coefficients and induced beneficial changes on intestinal morphology compared to sorghum and corn germ meal. All protein ingredients showed potential for use in piapara diets, except meat and bone meal .
Implementasi pariwisata berbasis masyarakat (CBT) di Coban Parang Tejo Malang
Authors: Asiyah Siti , Rachmadi Kartika Rose 
Published: August 2021

This study uses a qualitative descriptive approach with a SWOT analysis tool; namely Internal-external situation analysis which aims to determine the strengths and weaknesses as well as the factors that become opportunities and threats for the development of the Coban Parang Tejo tourism area in Malang, and the application and implementation of Community Based Tourism principles for the development of the Coban Parang Tejo tourism area.
The results of the study concluded that the concept of CBT has been applied in tourism management in Coban Parang Tejo (CPT) which was applied in the form of local community participation, the formation of a tourism village institution, environmentally friendly tourism management, the role of government, cooperation with investors and the creation of community business activities. From the SWOT analysis generated promotional strategies based on the strengths and weaknesses of tourism in CPT, 1) SO strategy by increasing the number of interesting vehicles adjusted to the local wisdom of the Perinci village community, so that it has its own distinct characteristics / uniqueness that is different from other tours; 2) ST Strategy by increasing the competitiveness of Coban Parang Tejo; 3) WO Strategy by increasing facilities / infrastructure and existing infrastructure; and 4) WT strategy by collaborating with investors and strengthening community communities. All of which are in the context of improving the welfare of the community.
The Role of Geological Models and Uncertainties in Safety Assessments
Authors: Bjorge Merle , Kreye Phillip , Heim Elisa , Wellmann Florian , Rühaak Wolfram 
Published: August 2021

Abstract
Safety assessments in nuclear waste management typically include the analysis of thermo-mechanical (TM) coupled processes. The TM behavior of the host rock is, amongst other aspects, dependent on the prevalent geological geometry. This study aims to evaluate the impact of uncertainties in geometry on the TM rock behavior. It is one of the very first studies aiming to bring uncertainties of structural geological models and numerical simulations together.To analyze the influence of geological geometries, a simplified model of the region around the Mont Terri rock laboratory was created. A 3-D structural geological model was set up and uncertainties of the lithological contacts were quantified by means of stochastic simulations, resulting in an ensemble of 89 model realizations. These realizations were transformed to a 2-D numerical model. In this numerical model, TM simulations were computed over a simulation time of 500 years, employing the Finite Element Method. To simulate a heat source of nuclear waste the lower edge of the model was set to 100°C.The results of these simulations show mean temperature variations of 90.89 °C and 92.70 ° after 500 years, with a maximum stress varying between 0.02 MPa and 0.16 MPa of elastic shear energy density and according mean cumulative displacements ranging from 30 cm to 38 cm. The presented results indicate that different model geometries and differences in material properties lead to noticeable variabilities of the TM behavior of claystone. However in this case, these variabilities would not significantly affect the integrity of the rock.
Circ-FURIN Expression Enhances Osteoblast Differentiation In Dental Pulp Stem Cells Via SOX11 Signaling Pathway Sponging miR-125
Authors: Ji Fang , Lin Yueting , Pan Jing , Yang Zhao , Ren Qianhui , Quan Jiubin , Wang Jian , Tao Jiang 
Published: August 2021

Abstract
Background: Many studies have found that circRNA plays a part in osteoblast differentiation. However, its mechanism remains unknown. Methods: High-throughput sequencing was used to identifield the different expression of circRNA during osteogenic dental pulp stem cells (DPSCs) differentiation. Luciferase report analysis and RT-qPCR were used to clarify the expression and regulation relationship among circ-FURIN, miR-125 and SOX11. The heterotopic bone formation experiment was further used to confirm the osteoblast differentiation of DPSC with different expression of circ-FURIN, miR-125 and SOX11. Results: Study indicated that circ-FURIN expression remarkably increased during osteoblast differentiation, yet circ-FURIN knockdown suppressed it. Bioinformatics and luciferase results discovered that miR-125 is the downstream target of circ-FURIN. Furthermore, circ-FURIN upregulation decreased miR-125 expression. MiR-125 upregulation restored the promotion effect of circ-FURIN on osteogenic DPSC differentiation. Luciferase report analysis verified that SOX11 is miR-125 downstream target. miR-125 overexpression suppressed osteogenic DPSC differentiation through targeting SOX11. SOX11 overexpression restored miR-125 inhibitory effect on osteogenic DPSC differentiation. In vivo experiments with heterotopic bone model suggested that circ-FURIN overexpression has crucial function to enhance heterotopic bone formation. Conclusions: In summary, circ-FURIN enhances osteoblast DPSC differentiation via the SOX11 signaling pathway by sponging miR-125. These findings suggest a novel therapeutic target for osteoporosis treatment.
Ambient Ozone Pollution and Daily Mortality in Hohhot, China: A Time-Series Study
Authors: Xia Chunyan , Liu Ying , Xie Jinli , Zheng Huiqiu , Niu Liwei , Zhang Nan , Lu Hong , Han Xia , Dong Lianying , Li Na , Wang Yangjie , Wang Yanling 
Published: August 2021

Abstract
Evidence on the effects of ozone on chronic lower respiratory disease (CLRD), acute respiratory infections (ARI) is still not conclusive. This study aimed to investigate the association between them in Hohhot China. Daily death counts, concentrations of PM2.5, PM10, SO2, NO2, and O3, and meteorological data were collected for Hohhot city from January 1, 2018, to December 31, 2019. We performed a time series analysis using generalized additive model (GAM). In single pollutant model, the estimated excess relative risks (EERs) for respiratory and CLRD mortality were 2.815% (95% CI: 0.075–5.630) at lag 04 and 4.409% (95% CI: 1.577–7.320) at lag 01, respectively, for each 10 µg/m3 increase in O3. No significant association was found for ARI and the other respiratory diseases mortality. Subgroup analysis showed that the respiratory diseases for men were more susceptible to O3 than women, while men had a lower association with CLRD than women. Concentrations of O3 were significantly associated with respiratory disease and CLRD for older adults. The significant positive association between O3 and respiratory mortality and CLRD mortality remained largely unchanged in the two-pollutant model and the multi-pollutant model. In conclusion, short-term exposure to O3 is significantly associated respiratory diseases and CLRD mortality, and this association is dominated by gender and age.
Identification of Genes Related to 68Ga-DOTATATE Organ Distribution in Homo Sapiens
Authors: Li Jiajin , Huang Gang , Liu Jianjun 
Published: August 2021

Abstract
Purpose 68Ga-DOTATATE is a somatostatin analogue that has been used for imaging neuroendocrine tumours. However, there is nonspecific uptake in some organs, and the reasons for that are not clear. The aim of the study is to outline the dynamic distribution pattern of 68Ga-DOTATATE in human body, and identify the genes responsible for 68Ga-DOTATATE uptake by bioinformatics analysis.Methods 68Ga-DOTATATE PET/CT was performed in 32 patients, and dynamic total-body PET scanning was performed with uEXPLORER. The gene expression datasets of human organs were downloaded from the Human Protein Atlas. WGCNA analysis was performed to screen the potential genes related to 68Ga-DOTATATE. BindingDB, SEA and SwissTargetPrediction databases were used to predict the potential binding proteins of DOTATATE based on molecular structure. Results Dynamic total-body PET scanning showed that 68Ga-DOTATATE uptake was not consistent with expression of SSTR2 in human organs. WGCNA analysis revealed 800 genes whose expression level was positively correlated to 68Ga-DOTATATE uptake. According to the molecular structure of DOTATATE, 135 proteins with potential binding ability to DOTATATE were screened by analysis based on drug database. Based on the results of the above two parts, 8 proteins were finally obtained, respectively AVPR1A, EPHA8, EPHB4, OPRL1, SSTR2, SSTR5, ST3GAL1 and NPY1R, which had potential binding possibility with DOTATATE, and their expression was positively correlated with 68Ga-DOTATATE uptake.Conclusion WGCNA analysis was combined with the drug database to obtain new potential binding targets of DOTATATE. The bioinformatics approach developed in this study could potentially be used to discover new potential binding targets for molecular imaging agents.
Under the dynamic environment of normal diagnosis and treatment in the bronchoscope room, the study of the removal efficiency of the new air purifier on microbial aerosols
Authors: Wu Lijuan , YAN XIXIN 
Published: August 2021

Abstract
Background

The SARS-CoV-2 can spread through droplets, aerosols, etc. In the case of a severe outbreak of the SARS-CoV-2, the use of new air purifiers in work and living places has a certain effect on reducing the spread of the SARS-CoV-2. There are abundant microbial aerosols in the indoor medical environment. The innovation of this experiment lies in the use of long-term, large-volume sampling methods under the multi-factor dynamic conditions of normal diagnosis and treatment in the bronchoscope room, and the use of two microbial detection methods at the same time to study the removal efficiency of the new air purifier on microbial aerosols ; The innovation of the new air purifier lies in outdoor fresh air and steady-state displacement flow technology.
Methods

In this experiment, the test group and the control group were set up. Gelatin filtration membrane and PTFE filtration membrane were used to sample the microbial aerosols in the bronchoscope room. Long time (39.5h) and large sampling volume (70590L) was used. A total of 16 days of pure working time sampling was carried out for a period of 1 month. The collected specimens were tested by two methods: next-generation sequencing (mNGS) and microbial culture identification. The researcher retrieved and recorded the microbiological test results of related patients, and compared them with the results of this experiment.
Results

The result of next-generation sequencing (mNGS): The total purification efficiency was 88.0%. Microbial culture counting and identification results: the total purification efficiency is 87.5%. The results are statistically significant. There is a certain correlation between the experimental results and the clinical microbiological test results of patients.
Conclusions

1. The new type of air purifier has a good effect on the removal of microbial aerosols in the bronchoscope room; 2. A variety of microorganisms involved in the experiment can be transmitted through aerosols.
Discussion

The new air purifier has a total removal efficiency of more than 85% of microorganisms under the dynamic environment of the hospital's normal diagnosis and treatment, and the purification efficiency of a single microorganism ranges 50%-100%. Such removal efficiency may have a positive effect for the control of the SARS-CoV-2 epidemic.
An Improved ECG Steganography Using Integer Wavelet Transform and Offset Coefficient with LSB Substitution
Authors: Yang Ching-Yu , Wang Wen-Fong 
Published: August 2021

Abstract
In this work, we present an improved steganography for electrocardiogram (ECG) hosts to solve the issues of existing ECG steganographic methods, which have less hiding capacity and insufficient signal-to-noise ratio (SNR)/ peak SNR (PSNR). Based on the integer wavelet transform (IWT) domain, sensitive (or private) data such as patients’ data and personal information can be efficiently embedded in an ECG host via the IWT coefficient adjustment and the least significant bit (LSB) technique. Simulations confirmed that the SNR/ PSNR, and payload of the proposed method outperform those of existing techniques. In addition, the proposed method is capable of resisting attacks, such as cropping, Gaussian noise-addition inversion, scaling, translation, and truncation attacks from third parties (or adversaries). Due to the fast computation time, the proposed method can be employed in portable biometric devices or wearable electronics.
Diabetes as a Risk Factor for Cardiovascular Events in Patients Receiving Permanent Pacemaker – A Propensity Score-Matched Cohort Study
Authors: Chen Huang-Chung , Liu Wen-Hao , Tseng Chien-Hao , Chen Yung-Lung , Lee Wei-Chieh , Fang Yen-Nan , Chong Shaur-Zheng , Chen Mien-Cheng 
Published: August 2021

Abstract
Background: Type 2 diabetes was associated with higher risk for permanent pacemaker (PPM) implantation. We aimed to compare the clinical outcomes between diabetic and non-diabetic patients receiving PPM treatment. Methods: Between January 2003 and December 2017, 1742 patients receiving naïve PPM treatment comprised this retrospective cohort study and were categorized into two groups by the presence or absence of diagnosis of diabetes: diabetic group (n=632, 36.3%) and non-diabetic group (n=1110, 63.7%). The primary outcome was cardiovascular events including heart failure (HF) hospitalization and acute myocardial infarction (AMI). Propensity score matching (PSM) was applied to reduce selection bias between the study groups. Results: During a mean follow-up of 7.8 ± 4.8 years, there were 264 cardiovascular events. A total of 746 patients with a 1:1 paired ratio between diabetic and non-diabetic groups were analyzed in the propensity score-matched series. After PSM, the incidence of cardiovascular events was higher in the diabetic group compared to the non-diabetic group (18.8% vs. 12.3%, P=0.015). Moreover, the incidence of HF hospitalization was higher in the diabetic patients compared to the non-diabetic patients (15.3% vs. 10.2%, P=0.037), whereas the incidence of AMI did not differ between the diabetic and non-diabetic groups (3.5% vs. 2.1%, P=0.268). After adjustments for covariates in multiple Cox regression analysis, diabetes remained as an independent predictor for cardiovascular events [hazard ratio, 1.54; 95% confidence interval, 1.04-2.29; P=0.031].Conclusions:In this cohort study of patients with naïve PPMs implantation, diabetes increased 1.54-fold risk of cardiovascular events in PPM recipients, especially for HF hospitalization.