bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE COMPARISON BETWEEN INTEGRATED AUDIO MEDIA OF YA LAL WATHAN AND POWER POINT MEDIA ON THE STUDENT'S COGNITIVE ABILITY
Authors: Wati Ana Reni Ratna , Ruswan Ruswan , Akmalia Hafidha Asni 
Published: November 2021

<p>The use of instructional media is one of the teacher's efforts to create maximum teaching and learning processes. Research on the use of integrated audio media Ya Lal Wathan in this study was carried out because the media used were new and had never been used by previous studies. This study aims to compare the effect of Ya Lal Wathan's integrated audio media and power point media on the cognitive abilities of high school students on Kingdom Plantae material. The study design used the Non-equivalent Control Group Design using a purposive sampling technique. We took all of students in MAN 1 Semarang as population and 2 classes as sample. The instruments used were 20 pre-test questions and 20 post-test questions given in power point and integrated audio class. Data were analyzed by Sign Test. The result of the study showed that there was an equally significant effect between two classes. However, students taught by integrated audio got an average grade in the post-test that is higher than the control class so there is a positive tendency that integrated audio media with Ya Lal Wathan is good for application in learning. It is necessary to innovate our audio media for further research.</p><p> </p>
Pelatihan Strategi Pengembangan UMKM melalui Jaringan Pemasaran Online di Dusun Kesongo Kecamatan Tuntang Kabupaten Semarang
Authors: Widiastuti Eko Heri , Setyaningsih Sri , Zusrotin Zusrotin , Sayekti Sri 
Published: November 2021

Kualitas SDM akan berpengaruh pada tingkat kesejahteraan suatu masyarakat atau keluarga, apabila suatu keluarga tingkat kesejahteraannya rendah, akan berakibat pada rendahnya aspek-aspek kehidupan lainnya. Di Dusun Kesongo Kecamatan Tuntang Kabupaten Semarang, mayoritas penduduknya bermatapencaaharian sebagai petani dan memiliki tingkat kesejahteraan menengah ke bawah. Keberadaan kelompok diharapkan menjadi sarana dan motivasi untuk meningkatkan kesejahteraan mereka. Permasalahan yang ditemukan yaitu belum maksimalnya pemanfaatan teknologi (HP) sebagai sarana promosi produknya. Untuk mengatasi berbagai persoalan tersebut yang paling utama adalah meningkatkan kualitas SDM anggota kelompok wanita tani dengan berbagai pelatihan terutama yang menyangkut kemampuan pemanfaatan penggunaan teknologi (HP) khususnya media sosial sebagai sarana pengembangan usaha yang merekabangun. Luaran yang hendak dicapai adalah meningkatan pemanfaatan media sosial melalui HP sebagai sarana untuk pengembangan UMKM dari kelompok wanita tani. Hasil kegiatan dari pengabdian ini sangat bermanfaat, sebab memunculkan motivasi untuk meningkatkan pengembangan usaha yang semakin baik, pengelolaan, sarana prasaranya juga dapat dipenuhi walaupun masih skala kecil. Peningkatan produksi dan perluasan pemasaran secara perlahan juga dapat ditingkatkan. Namun ada kendala yang dihadapi dari anggota kelompok sinyal yang tidak stabil.
Kata Kunci : pemasaran on-line, UMKM
Ensino interdisciplinar do tema energia eólica
Authors: Couto Mohammed Luiz Santos , José Wagner Duarte , Campos Simara Santos 
Published: November 2021

Esse artigo analisa o desenvolvimento de uma sequência didática pautada na estratégia FlexQuest® na perspectiva da Teoria da Flexibilidade Cognitiva formulada por Spiro e colaboradores, e possíveis contribuições dessa abordagem para a Alfabetização Científica e Tecnológica proposta por Fourez. O objetivo é verificar a presença dos pressupostos da Alfabetização Científica e Tecnológica no ensino do tema energia eólica nas aulas de física de uma turma do 3º ano de uma escola de Ensino Médio Integrado à Educação Profissional, localizada numa região do interior do Estado da Bahia proeminente na produção de energia eólica. A sequência didática foi estruturada a partir de casos e minicasos representativos de situações reais, organizados didaticamente na plataforma FlexQuest®. Os dados de pesquisa foram obtidos dos registros de áudio gravados das aulas, de diários de bordo, de atividades realizadas pelos estudantes na plataforma e de seus manuscritos. A análise considerou a articulação dos pressupostos da Teoria da Flexibilidade Cognitiva e da Alfabetização Científica e Tecnológica. Os resultados alcançados sugerem que a problematização do tema segundo a travessia da paisagem sob diversas direções favoreceu o desenvolvimento da flexibilidade cognitiva e da autonomia, comunicação e domínio pelos estudantes, indícios de potencial contribuição dessa articulação para a Alfabetização Científica e Tecnológica.
Superzoom. Italia y el compromiso radical
Authors: Parga Marcos 
Published: November 2021

Italy: the new domestic landscape, la ambiciosa exposición que en 1972 tuvo lugar en el MoMA, supone la consagración y a la vez escenifica la muerte de lo que algunos críticos acababan de catalogar como Arquitectura Radical, término con el que intentaban unificar el trabajo de un heterogéneo y atomizado grupo de arquitectos, principalmente italianos, comprometidos con el replanteamiento total de la definición y objetivos de la disciplina.
Se ponía fin así a un corto pero intenso periodo dinamitado por multitud de propuestas experimentales durante el que se generó la última arquitectura con aspiraciones socio-políticas, responsable de un vibrante legado teórico que proclamaba la vuelta a las raíces olvidadas de la profesión y que se mostraba más preocupada por reflexionar sobre sus fundamentos que por perpetuar la práctica de un oficio puesto en crisis.
Tank-mix Options for Control of Tropical Soda Apple and Dogfennel
Authors: Sellers Brent A. , Ferrell Jason A. 
Published: November 2021

SS-AGR-300, a 2-page illustrated fact sheet by B.A. Sellers and J.A. Ferrell, describes results of UF/IFAS studies of combinations of herbicides for control of dogfennel growing alongside TSA. Published by the UF Department of Agronomy, January 2008.
SS-AGR-300/AG306: Tank-Mix Options for Control of Tropical Soda Apple and Dogfennel (ufl.edu)
Handbook of Florida Agricultural Laws: General Agriculture-Related Laws
Authors: Olexa Michael T. , Alperstein Ian , Fischer Joseph 
Published: November 2021

Revised! Circular 1224, a handbook broken into 8 parts, by Michael T. Olexa, Ian Alperstein, and Joseph Fischer, provides an accurate, current, and authoritative summary of the principal Florida laws that directly or indirectly relate to agriculture. It provides a basic overview of the many rights and responsibilities that farmers and farmland owners have under Florida laws. Published by the UF Department of Food and Resource Economics, December 2007.
FE114/FE114: Handbook of Florida Agricultural Laws: General Agriculture-Related Laws (ufl.edu)
Ask IFAS: Handbook of Florida Agricultural Laws (Circular 1224) (ufl.edu)
Handbook of Florida Agricultural Laws: Taxation and Property Rights Related to Agricultural Lands
Authors: Olexa Michael T. , Alperstein Ian , Fischer Joseph 
Published: November 2021

Revised! Circular 1224, a handbook broken into 8 parts, by Michael T. Olexa, Ian Alperstein, and Joseph Fischer, provides an accurate, current, and authoritative summary of the principal Florida laws that directly or indirectly relate to agriculture. It provides a basic overview of the many rights and responsibilities that farmers and farmland owners have under Florida laws. Published by the UF Department of Food and Resource Economics, December 2007.
FE119/FE119: Handbook of Florida Agricultural Laws: Taxation and Property Rights Related to Agricultural Lands (ufl.edu)
Ask IFAS: Handbook of Florida Agricultural Laws (Circular 1224) (ufl.edu)
Nitrogen in the Home Landscape
Authors: Shober Amy L. 
Published: November 2021

SL-254, 3-page illustrated fact sheet by Amy L. Shober, helps homeowners understand how N interacts in the environment through the nitrogen cycle, making maintenance of home landscapes or gardens easier and more sustainable. Published by the UF Soil and Water Sciences Department, December 2007.
SL 254/SS479: Nitrogen in the Home Landscape (ufl.edu)
Soil pH and the Home Landscape or Garden
Authors: Shober Amy L. , Denny Geoffrey C. 
Published: November 2021

SL-256, 3-page illustrated fact sheet by Amy L. Shober and Geoffrey C. Denny, explains soil pH for a homeowner audience and provides strategies to make the most of the pH in home landscapes and gardens. Published by the UF Soil and Water Sciences Department, January 2008.
SL 256/SS480: Soil pH and the Home Landscape or Garden (ufl.edu)
Pemanfaatan Limbah Kelapa Menjadi Kerajinan Bernilai Ekonomi di Desa Kanoman (Studi Kasus Desa Kanoman, Kec. Panjatan, Kab. Kulonprogo)
Authors: Afiq Ikhwan Nur , Saputra Dedi Adi , Maryani Ina , Fallah M. Fajrul , Asih Hayati Mukti 
Published: November 2021

Negara Indonesia merupakan salah satu Negara yang memiliki tanaman kelapa terbesar, hampir setiap wilayah secara merata di Indonesia menghasilkan tanaman kelapa, limbah kelapa yang ada saat ini hanya dipandang oleh masyarakat sebagai sampah yang kotor, tidak berguna dan tak ada nilainya, sehingga masyarakat membiarkanya berserakan dimana-mana dan bahkan membuangnya disembarang tempat yang sebenarnya akan sangat berdampak pada lingkungan sekitar, permasalahan ini banyak sekali kita temukan pada desa atau wilayah yang banyak ditumbuhi oleh tumbuhan kelapa, termasuk Desa Kanoman. Pengabdian masyarakat dalam memanfaatkan limbah kelapa sangat diperlukan untuk memanfaatkan dan mengelola limbah kelapa menjadi sebuah kerajinan yang memiliki nilai jual tinggi, dalam pengabdian ini kita menggunakan metode yang sesuai dengan kondisi saat ini yaitu belanded atau dapat diartikan online dan offline. Setelah di lakukannya pengabdian pada Desa Kanoman, pengetahuan masyarakat tentang bagaimana memanfaatkan limbah kelapa menjadi sebuah kerajinan yang memiliki nilai jual meningkat sebanyak 60% , baik secara pengetahuan maupun dalam praktiknya setelah dilakukannya penyuluhan, dan praktik pembuatan kerajinan.
Strategi Peningkatan Kinerja UMKM Wisata Pantai Berbasis Digital (Kasus Wisata Pantai Desa Sawarna, Kec. Bayah, Lebak, Banten)
Authors: Darmansyah Asep , Sutardi Acip , Afgani Kurnia Fajar , Susanto Eko , Syaputri Annisa Rizkia , Khaerani Fitria Rahayu 
Published: November 2021

Desa Sawarna, Kecamatan Bayah merupakan desa primadona wisata pantai di Kabupaten Lebak Propinsi Banten karena memiliki keindahan alamnya yang sangat mempesona. Pelaku UMKM bermunculan melengkapi kesempurnaan sarana wisata pantai, seperti rumah makan, kafe, gerai oleh-oleh, jasa transportasi, jasa penginapan, jasa pemandu wisata, dan jasa persewaan kendaraan. Era new normal menjadi garis awal para pelaku UMKM untuk kembali menggerakkan roda bisnisnya, dengan menyiapkan diri masuk ke platform digital. Kegiatan pengabdian masyarakat ini bertujuan menyiapkan UMKM wisata pantai untuk menerapkan model pemasaran dan pembukuan berbasis digital sehingga pemasaran meluas, jarak mendekat, transaksi cepat, dan pengambilan keputusan tepat. Tim LPPM ITB bekerja sama dengan POKDARWIS Desa Sawarna mengadakan pelatihan dan pembinaan digitalisasi bisnis dengan metode pendekatan individu dan kelompok. Survey awal sebelum pelatihan menunjukkan bahwa UMKM wisata pantai Desa Sawarna masih memiliki pengetahuan yang minim tentang pemasaran dan pembukuan digital. Pelatihan berisikan langkah-langkah pemahamaan teori dan praktek e-commerce dan pembukuan digital. Pelatihan membuka cakrawala pengetahuan UMKM tentang pentingnya digitalisasi bisnis, dan memotivasi UMKM untuk beralih ke platform digital yang akan mengagregasi digitalisasi bisnis secara keseluruhan. Paska pelatihan perlu terus didorong dan difasilitasi lebih lanjut oleh pihak-pihak terkait.
Perlakuan Biaya Pendidikan dan Pelatihan pada Balai Diklat Keuangan Balikpapan : Pendekatan Activity Based Costing
Authors: Miswaty Miswaty , Lista Ade 
Published: November 2021

Balai Diklat Keuangan Balikpapan adalah salah satu unit vertikal yang berada di bawah Badan Pendidikan dan Pelatihan Keuangan yang memiliki tugas dan fungsi melaksanakan pendidikan dan pelatihan bagi Aparatur Sipil Negara (ASN) Kementerian Keuangan melalui pendidikan dan pelatihan keuangan negara di daerah, dengan wilayah kerja yaitu Kalimantan Timur, Kalimantan Utara, dan Kalimantan Selatan. Pada tahun 2019, pada tahun 2019 mengelola Daftar Isian Pelaksanaan Anggaran (DIPA) sebesar Rp10.515.220.000. Data realisasi dan capaian penyerapan DIPA pada Balai Diklat Keuangan Balikpapan sampai dengan akhir tahun anggaran 2019 yaitu sebesar Rp10.152.079.589. Pada tahun 2019 Balai Diklat Keuangan Balikpapan telah menyelenggarakan sebanyak 27 pelatihan dengan realisasi peserta sebanyak 956 peserta. Salah satu pelatihan yang diselenggarakan adalah Pelatihan Dasar (Latsar) CPNS Golongan II Periode II dengan rencana peserta 60 orang dan realisasi peserta sebanyak 59 orang atau sebesar 98,33%.
Terdapat perbedaan hasil perhitungan ABC System dengan Standar Biaya yang digunakan oleh Balai Diklat Keuangan Balikpapan. Perbedaan perhitungan terjadi karena dalam perhitungan sesuai Standar Biaya hanya menghitung biaya yang terkait secara langsung dengan diklat saja yaitu untuk komponen Direct Material dan Direct Labor, sedangkan perhitungan berdasarkan Activity Based Costing System menghitung seluruh biaya yang terkait dengan diklat yang berupa direct material, direct labor, dan factory overhead. Dengan demikian selisih diantara keduanya adalah senilai factory overhead.
Interaction between Pre-School Children’s Physical Activity and Physical Fitness and Their Parents’ Physical Activity
Authors: Rutkauskaitė Renata , Daniusevičiūtė-Brazaitė Laura , Jaruševičiūtė Emilė 
Published: November 2021

Background. Pre-school age is the period of especially fast growth and physical development, characterized by an intensive growth and development of a child’s organism, great changes in the activity of the functional systems, which is affected by increasing physical activeness and fitness (Grinienė & Vaitkevičius, 2009; Howells & Sääkslahti, 2019). Previous studies have identified parental influence as a factor that can shape a child’s physical self–perception and act as a stimulus for physical activity and fitness (Eddolls, McNarry, Stratton, & Mackintosh, 2016). The aim of this study was to indicate physical activity of 5–6-year-old children and to determine the interaction between parents’ physical activity and physical fitness data.
Methods. The study involved pre-school age children (n = 59) from 5 to 6 years old: 31 girls and 21 boys; also, their parents (n = 101) were involved: 57 mothers and 44 fathers. Physical activity was measured objectively using the ActiGraph GT3X model. The children performed five physical fitness tests (PFT) according to the Eurofit methodology. Also, parents were asked to fill in questionnaires about their own and their children’s physical activity, and also subjective physical fitness.
Results. It turned out that there was a significant difference in the time spent in moderate and moderate to vigorous (MVPA) physical activity between 5 to 6-year-old children (p < .05). Comparing pre-school children’s physical fitness by gender we found that boys were more physically fit than girls when performing long jumps, but girls were more physically fit than boys when performing a sit and reach test (p < .05). Subjectively measured PA identified that 72.6% of parents (of both genders) were sufficiently physically active and 27.4% were inadequate physically active.
Conclusion. The results revealed that 6-year-old children spent more time in sedentary time than 5-year-olds, who accumulated more time in moderate and total MVPA physical activity per day. No significant relation was found between parents’ and children’s physical activity and fitness.

Keywords: physical activity, physical fitness, pre-school child, health, parents.
Expression of Sport Experiences between Cadet and Junior Basketball Players
Authors: Malinauskas Romualdas , Zablockis Šarūnas , Ajauskas Šarūnas 
Published: November 2021

Background. The hypothesis of this study is formulated as follows: the experience of junior basketball players in competitions will be more valuable than that of cadet basketball players. The aim of our study was to examine the peculiarities of youth and basketball players’ sport experiences.
Methods. A total of 104 basketball players, 47 cadets and 57 juniors participated in the study. Survey questionnaire is used for the study. The following methodologies were used: Athlete’s Personal Experience Survey (Athletic Coping Skills Inventory, ACSI-28) and the Sport Experiences Questionnaire (SEQ).
Results. The results of the study revealed statistically significant differences (p <.05) in personal sport experiences (athletic endurance skills) among basketball players of different age groups according to the following indicators: the coach’s influence on basketball players, concentration, athletes’ self-confidence and resilience. The results of the study of athletes’ competitive experiences revealed that there were statistically significant differences (p <.05) between cadet and junior basketball players in competition experience. No statistically significant differences were found in terms of risk and progress parameters.
Conclusions. The coach’s influence was greater for the cadet basketball players. Concentration, self-confidence and resilience were better among junior basketball players. This shows that when competing, junior basketball players have higher levels of concentration compared to the cadet group, as they are more confident and can better cope with tension. In addition, it was found that the experience of junior basketball players in competitions is richer than that of cadet basketball players.
Keywords: sport experience, junior, cadet, basketball players, basketball.
LTF Regulates the Immune Microenvironment of Prostate Cancer Through JAK/STAT3 Pathway
Authors: Zhao Qi , Cheng Yingying , Xiong Ying 
Published: November 2021

BackgroundThe study of the immune microenvironment in prostate cancer (PRAD) has brought new opportunities for the current traditional treatment regimens. Therefore, our goal is to develop a universal immunodiagnostic marker to improve patient survival.MethodsBioinformatics analysis: We collected 591 samples from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) cohorts and evaluated the abundance and distribution of immune cell members in the PRAD expression profile matrix in the mixed cell population by CIBERSORT, ESTIMATE, single-sample gene set enrichment analysis (ssGSEA), and other methods. The target genes related to PRAD immune microenvironment and tumor mutation load were obtained by overlap analysis and verified by pan-cancer analysis. Cell experiment: The cell transfection scheme was designed, and the experiment was divided into three groups: overexpressing lactoferrin (LTF) group, empty plasmid group, and control group. After obtaining cells in each group, the gene and protein expression levels of LTF and signal transduction of signal transducer and activator of transcription 3 (STAT3) and granulocyte-macrophage colony-stimulating factor (GM-CSF) in the above three groups were detected by real-time PCR and Western blot, respectively. Finally, the level of GM-CSF secretion in the three groups was detected by ELISA.ResultsMacrophages, resting mast cells, and plasma cells play an important role in PRAD immune microenvironment. In addition, high tumor mutation load [tumor mutational burden (TMB)] was positively correlated with lymph node metastasis in patients with PRAD. As the core gene of the PRAD immune microenvironment, the low expression of LTF in PRAD promotes the occurrence of immunodeficiency, PRAD, and the enrichment of the Janus kinase (JAK)/STAT3 signal pathway. Through cell experiments, it was found that the content of LTF mRNA and protein increased significantly, while the content of STAT3 and GM-CSF mRNA and protein decreased significantly in the overexpressed LTF group. The level of GM-CSF in the supernatant of cell culture was significantly decreased in the overexpression group of LTF.ConclusionThe core gene we proposed is one of the most promising biomarkers to improve the overall survival rate of PRAD and provides an important theoretical basis for the study of the mechanism of the LTF-mediated JAK/STAT3 pathway in PRAD.
Survival Outcomes of Local Compared With Systemic First Treatment of Non-Small Cell Lung Cancer Brain Metastases
Authors: Liu Hong-Mei , Meng Chun-Liu , Zhao Lu-Jun 
Published: November 2021

ObjectiveThis retrospective study evaluated the survival advantage of local treatment targeted to brain metastases, relative to systemic therapy, as the first option for brain metastases of non-small cell lung cancer (NSCLC).MethodsFirst reviewed were 291 cases of NSCLC brain metastases from two centers. All patients were at least 18 years old, with histologically confirmed NSCLC, and required and underwent both local (radiotherapy or brain surgery) and systemic treatment (chemotherapy and tyrosine kinase inhibitor [TKI] medication). Demographics, clinical characteristics, and treatment-related variables were collected.ResultsThe final population comprised 160 patients. Overall, the multivariate analysis suggested that the following were associated with better survival: &gt;3 cycles of chemotherapy; stereotactic radiosurgery; and TKI medication (all, P = 0.000). Local treatment that began within 1 week of the diagnosis of brain metastases was associated with poorer survival (P = 0.006). Among the 111 patients with symptomatic brain metastases, the multivariate analysis indicated that better survival was associated with &gt;3 cycles of chemotherapy (P = 0.000), radiation dose &gt;40 Gy (P = 0.001), stereotactic radiosurgery (P = 0.000), and TKI medication (P = 0.000), while local treatment that began within 1 week after the diagnosis of brain metastases was associated with poorer survival (P = 0.015).ConclusionsFor patients with NSCLC brain metastases, regardless of the presence of clinical symptoms associated with brain metastases, systemic treatment before local may be better for survival. Even when used to relieve clinical symptoms, local treatment should be within a setting of sufficient systemic treatment.
Carfilzomib: A Promising Proteasome Inhibitor for the Treatment of Relapsed and Refractory Multiple Myeloma
Authors: Jayaweera Shansa Pranami E. , Wanigasinghe Kanakanamge Sacheela Prasadi , Rajalingam Dharshika , Silva Gayathri N. 
Published: November 2021

The proteasome is crucial for the degradation of intracellular proteins and plays an important role in mediating a number of cell survival and progression events by controlling the levels of key regulatory proteins such as cyclins and caspases in both normal and tumor cells. However, compared to normal cells, cancer cells are more dependent on the ubiquitin proteasome pathway (UPP) due to the accumulation of proteins in response to uncontrolled gene transcription, allowing proteasome to become a potent therapeutic target for human cancers such as multiple myeloma (MM). Up to date, three proteasome inhibitors namely bortezomib (2003), carfilzomib (2012) and ixazomib (2015) have been approved by the US Food and Drug Administration (FDA) for the treatment of patients with relapsed and/or refractory MM. This review mainly focuses on the biochemical properties, mechanism of action, toxicity profile and pivotal clinical trials related to carfilzomib, a second-generation proteasome inhibitor that binds irreversibly with proteasome to overcome the major toxicities and resistance associated with bortezomib.