bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect and Relationship of Seasons on the High Risk of Ovarian Hyperstimulation Syndrome After Oocyte Retrieval in Patients With Polycystic Ovary Syndrome
Authors: Cao Yurong , Shi Hao , Ma Yue , Ma Linna , Zhai Jun 
Published: January 2021

ObjectiveTo investigate the effect of seasons on the incidence of high risk of ovarian hyperstimulation syndrome (OHSS) after in oocyte retrieval in patients with polycystic ovarian syndrome (PCOS) and to establish a nomogram to predict the risk of OHSS.DesignSingle-center, retrospective study.SettingUniversity-affiliated reproductive medicine center.Patient(s)A total of 2,030 infertility patients with PCOS underwent the follicular phase long-acting long protocol IVF/ICSI in the reproductive medicine center from January 2017 to December 2019.Intervention(s)None.Main outcome measure(s)Logistic regression analysis was used to analyze the factors associated with a high risk of OHSS. We established a nomogram to predict the risk of OHSS in infertility patients with PCOS after oocyte retrieval.Result(s)The incidence of patients at high risk of OHSS was significantly different from season-to-season and was especially higher in the summer and winter. Multivariate logistic analysis showed that gonadotropin dosage, number of retrieved oocytes, estradiol level, average bilateral ovarian diameter on the day human chorionic gonadotropin was administered, type of infertility, and average temperature were independent risk factors for OHSS after oocyte retrieval in PCOS patients. Based on the above independent risk factors, we constructed a prediction model for OHSS risk. To evaluate the efficiency of the prediction model, we calculated the C-index (0.849), area under the receiver operating characteristic curve (0.849), and internal validation C-index (0.846). Decision curve analysis suggested that the prediction model exhibited significant net benefits.Conclusion(s)The incidence of PCOS patients at high risk for OHSS after oocyte retrieval fluctuated with seasonal temperature changes, and was significantly higher in extreme climates. The prediction model had favorable predictive performance and clinical application value.
68Ga-DOTATOC PET/CT-Based Radiomic Analysis and PRRT Outcome: A Preliminary Evaluation Based on an Exploratory Radiomic Analysis on Two Patients
Authors: Liberini Virginia , Rampado Osvaldo , Gallio Elena , De Santi Bruno , Ceci Francesco , Dionisi Beatrice , Thuillier Philippe , Ciuffreda Libero , Piovesan Alessandro , Fioroni Federica , Versari Annibale , Molinari Filippo , Deandreis Désirée 
Published: January 2021

Aim: This work aims to evaluate whether the radiomic features extracted by 68Ga-DOTATOC-PET/CT of two patients are associated with the response to peptide receptor radionuclide therapy (PRRT) in patients affected by neuroendocrine tumor (NET).Methods: This is a pilot report in two NET patients who experienced a discordant response to PRRT (responder vs. non-responder) according to RECIST1.1. The patients presented with liver metastasis from the rectum and pancreas G3-NET, respectively. Whole-body total-lesion somatostatin receptor-expression (TLSREwb-50) and somatostatin receptor-expressing tumor volume (SRETV wb-50) were obtained in pre- and post-PRRT PET/CT. Radiomic analysis was performed, extracting 38 radiomic features (RFs) from the patients' lesions. The Mann–Whitney test was used to compare RFs in the responder patient vs. the non-responder patient. Pearson correlation and principal component analysis (PCA) were used to evaluate the correlation and independence of the different RFs.Results: TLSREwb-50 and SRETVwb-50 modifications correlate with RECIST1.1 response. A total of 28 RFs extracted on pre-therapy PET/CT showed significant differences between the two patients in the Mann–Whitney test (p &lt; 0.05). A total of seven second-order features, with poor correlation with SUVmax and PET volume, were identified by the Pearson correlation matrix. Finally, the first two PCA principal components explain 83.8% of total variance.Conclusion: TLSREwb-50 and SRETVwb-50 are parameters that might be used to predict and to assess the PET response to PRRT. RFs might have a role in defining inter-patient heterogeneity and in the prediction of therapy response. It is important to implement future studies with larger and more homogeneous patient populations to confirm the efficacy of these biomarkers.
Microsurgery vs. Gamma Knife Radiosurgery for the Treatment of Brainstem Cavernous Malformations: A Systematic Review and Meta-Analysis
Authors: Gao Xiangyu , Yue Kangyi , Sun Jidong , Cao Yuan , Zhao Boyan , Zhang Haofuzi , Dai Shuhui , Zhang Lei , Luo Peng , Jiang Xiaofan 
Published: January 2021

Background: Brainstem cavernous malformations (BSCMs) are a subset of cerebral cavernous malformations with precarious locations and potentially devastating clinical courses. The effects and outcomes of treating BSCMs by microsurgery or gamma knife radiosurgery (GKRS) vary across studies.Methods: We searched the Medline, Web of Science, The Cochrane Library, PubMed, and China Biology Medicine disc databases for original articles published in peer-reviewed journals of cohort studies reporting on 20 or more patients of any age with BSCMs with at least 80% completeness of follow-up.Results: We included 43 cohorts involving 2,492 patients. Both microsurgery (RR = 0.04, 95% CI 0.01–0.16, P &lt; 0.01) and GKRS (RR = 0.11, 95% CI 0.08–0.16, P &lt; 0.01) demonstrated great efficacy in reducing the rehemorrhage rate after treatment for BSCMs. The incidence rates of composite outcomes were 19.8 (95% CI 16.8–22.8) and 15.7 (95% CI 11.7–19.6) after neurosurgery and radiosurgery, respectively. In addition, we found statistically significant differences in the median numbers of patients between neurosurgical and radiosurgical cohorts in terms of symptomatic intracranial hemorrhage (ICH; neurosurgical cohorts: median 0, range 0–33; radiosurgical cohorts: median 4, range 1–14; P &lt; 0.05) and persistent focal neurological deficit (FND; neurosurgical cohorts: median 5, range 0–140; radiosurgical cohorts: median 1, range 0–3; P &lt; 0.05).Conclusions: The reported effects of treating BSCMs by microsurgery or GKRS are favorable for reducing recurrent hemorrhage from BSCMs. Patients in the neurosurgery cohort had a lower incidence of symptomatic ICH, while patients in the radiosurgical cohort had a lower incidence of persistent FND.
A Systematic Review of the European Rapid Alert System for Food and Feed: Tendencies in Illegal Food Supplements for Weight Loss
Authors: Koncz Dorottya , Tóth Barbara , Roza Orsolya , Csupor Dezső 
Published: January 2021

Background: Slimming products represent a dynamically growing group of food supplements worldwide. The efficacy of safely usable natural ingredients is usually below consumers’ expectations. Certain manufacturers add unauthorized or prohibited ingredients to weight loss supplements in order to increase their efficacy. Hence, many of these products are adulterated and may pose a risk to the consumers’ health.Aims: The aim of our work was to give an overview on natural ingredients used in slimming products, to summarize the frequently used synthetic adulterants and also to assess the trends of adulterated and illegal food supplements in the European Union based on the warnings of the Rapid Alert System for Food and Feed (RASFF) in the time period of 1988–2019.Methods: Reports between 1988–2019 were extracted from the RASFF portal on January 1, 2020. Each entry was individually reviewed.Results: 2,559 records of food supplements with quality problems were identified in the RASFF, several of which [319 (12,5%)] were marketed to facilitate weight loss. 202 (63,3%) contained unapproved, synthetic drug ingredients. The major adulterant (113 of 319, 35.4%) was DNP (2,4-dinitrophenol), whereas sibutramine was the second most frequent adulterant agent (69 products, 21,6%) between 1988 and 2019.Conclusion: The number of approved medicines for the indication of weight loss is relatively low and their efficacy (and also that of the natural ingredients) is limited. Therefore, a significant number of weight loss supplements is adulterated to satisfy patients’ expectations. Hence, these products may cause serious adverse effects in sensitive patients.
Factors Associated With Self-Selected Step Rates Between Collegiate and High School Cross Country Runners
Authors: Luedke Lace E. , Rauh Mitchell J. 
Published: January 2021

Introduction: Cross country is a popular high school and collegiate sport with a high rate of running-related injuries (RRI). Among high school runners, higher step rates have been associated with greater running experience and decreased body height, and lower step rates have been prospectively associated with increased risk of shin RRI. These associations have not been reported in collegiate cross country runners. The purpose of this study was to compare step rates between collegiate and high school cross country runners. Secondary objectives included determining if step rates in collegiate runners were related to experience and anthropometric variables, and whether their self-selected step rates were prospectively related to lower extremity RRI.Materials and methods: Twenty-nine NCAA Division III collegiate cross country runners (13 females, mean ± SD age 19.7 ± 1.3 years) completed a survey and ran at their self-selected speed. Step rate was assessed with Polar RCX5 wristwatches and S3+ Stride Sensors™ on the first day of the season. Runners were followed during the season for occurrence of time-loss lower extremity RRI. A cohort of 68 high school runners was used for comparison of step rates at their self-selected speeds.Results: Collegiate runners' self-selected step rates (177.1 ± 7.2 spm [steps per minute]) were higher than high school runners' (171.3 ± 8.3 spm) (p = 0.01). Collegiate runners ran at higher self-selected speeds (4.6 ± 0.5 m/s) than the high school runners (3.8 ± 0.5 m/s) (p &lt; 0.001). A lower percentage of collegiate runners ran at ≤166 spm than high school runners. Body mass was negatively correlated with step rate in collegiate runners. During the season, 41.3% of collegiate runners experienced lower extremity RRI. Step rates for collegiate runners who did not experience RRI (178.9 ± 7.7 spm) were not significantly higher than runners who did experience RRI (174.5 ± 5.7 spm) (p = 0.10).Discussion: Higher step rates were found in collegiate than high school runners, but the difference was partially explained by higher self-selected running speeds. Thus, variations in step rate between high school and collegiate runners may be expected based on experience, speed, and body mass.
PROBLEMS OF PROVIDING COWS CONCENTRATES IN AUTOMATIC MILKING SYSTEMS
Authors: ШАРИПОВ Д.Р. , ЯКИМОВ О.А. , ГАЛИМУЛЛИН И.Ш. 
Published: January 2021

Изучена технология дополнительного скармливания концентрированных кормов во время доения в условиях системы автоматизированного доения на коровах голштинской породы, разделенных на 6 групп по молочной продуктивности. Исследования показали, что с повышением молочной продуктивности в группах коров увеличивается количество выданных и потребленных концентратов. Аналогичная закономерность установлена по времени посещения доильной станции на количество потребления комбикорма, чем дольше коровы задерживаются в боксах доения, тем больше концентрированных кормов они потребляют. Животные всех групп неполностью съедают комбикорм, получаемый на станции доения, остатки концентратов от выданной нормы в группе коров с удоем менее 20,0 кг составили 8,3%, 20,1—25,0 кг — 3,6%, 25,1—30,0 кг — 5,9%, 30,1—35,0 кг — 8,9%, 35,1—40,0 кг — 7,9% и в группе с удоем более 40,1 кг — 7,5%. Анализ затрат концентрированных кормов,получаемых на станции доения, на 1 кг молока показал, что группы коров с удоем 35,1—40,0 и более 40,1 кг на 11,5—18,9% недополучают концентратов, обратная тенденция в группе коров с удоем 20,1—25,0 и менее 20,0 кг, которым для сохранения интереса к роботизированной установке требуется на 9,4—10,4% больше концентрированных кормов.
The technology of additional feeding of concentrated feeds during milking under the conditions of an automatic milking system on Holstein cows, divided into 6 groups according to milk production, has been studied. Studies have shown that with an increase in milk production in the groups of cows, the amount of concentrates allocated and consumed increases. The influence of box-visiting time per milking on the amount of concentrate consumption has been established, the longer the cows stay in the milking boxes, the more concentrated feed they consume. Animals of all groups do not fully consume the compound feed obtained in the milking box, the remains of concentrates from the given norm in the group of cows with a milk yield of less than 20.0 kg was 8.3%, in the group of 20.1—25.0 kg — 3.6%, in the group of 25, 1—30.0 kg — 5.9%, in the group of 30.1—35.0 kg — 8.9%, in the group of 35.1—40.0 kg — 7.9% and in the group with a milk yield of more 40.1 kg — 7.5%. Analysis of the costs of concentrated feed per kg of milk received at the milking box showed that groups of cows with a yield of 35.1—40.0 and more than 40.1 kg at 11.5—18.9% do not receive concentrates, the opposite trend is a group of cows with a milk yield of 20.1—25.0 and less than 20.0 kg, which require 9.4—10.4% more concentrated feed to maintain interest in a robotic unit.
Study on the stress and mechanism of self-separated GaN grown by Na-flux method
Authors: Si Zhiwei , Liu Zongliang , Gu Hong , Dong Xiaoming , Gao Xiaodong , Ren Yujiao , Wang Xiao , Wang Jianfeng , Xu Ke 
Published: January 2021

Abstract
A 2 inch free-standing c-plane GaN wafer was fabricated through in situ self-separation using HVPE-seed crystal etching back (HCEB) by intentionally adjusting the nitrogen pressure in the Na-flux growth process of GaN. First, adjust the nitrogen pressure in the reactor to a lower level to facilitate HCEB to form a large number of voids at the interface between the c-plane HVPE seed and the c-plane Na-flux GaN. After regrowth of approximately 340 μm thick Na-flux GaN, self-separation was achieved during the cooling process. The free-standing GaN wafer was almost stress-free as a result of strain relief by the in situ self-separation process, which was confirmed by room-temperature Raman and low-temperature photoluminescence measurements. It is supposed that the HCEB process can be applied to fabricate high-quality free-standing GaN wafers in the future.
Decades of Party Distrust. Persistence through Reform in Italy
Authors: Bergman Matthew E. , Passarelli Gianluca , Serricchio Fabio 
Published: January 2021

One common feature of the Italian political space over the past half century has been the presence of distrust in political parties and the presence of anti-system parties on both the left and the right. Discontent with existing elites and the political system has taken many forms, including referendums altering the electoral system. Both the character of the main parties and the rules by which they are elected have been reformed 4 times since the 1980s. However, as the elections of 2013 and 2018 and the referendum of 2016 demonstrate, Italians still have a high amount of resentment towards party elites and the operation of the system. Using data from Italian National Election Studies, this paper traces the development of this party resentment with a focus on three questions: 1) How has resentment towards party representiveness changed with the electoral and party reforms 2) Who was likely to hold this resentment 3) What was the party affiliation of those most resentful, or did they abstain? Results stress that socio-demographic differences had little effect on understanding the source of party resentment; distrust in parties correlates well with distrust in parliament and political administration. General social distrust did not translate into a distrust for parties. We conclude that discontent can be separated into a political dimension associated with current governance and one of a more systemic nature.
VALIDASI DATA CURAH HUJAN SATELIT TRMM DAN PERSIANN DALAM ANALISIS DEBIT BANJIR RENCANA DI DAS TELAGA LEBUR
Authors: Mulyandari Erni , Susila Herman 
Published: January 2021

Perkiraan debit banjir perlu dilakukan untuk meminimalisasi terjadinya kerusakan di tubuh bendungan, terutamanya di Waduk Telaga Lebur (DAS Telaga Lebur). Perkiraan debit banjir biasanya menggunakan data hujan terukur permukaan (ground data hujan) dari stasiun hujan, akan tetapi di DAS Telaga Lebur data hujan yang tersedia tidak lengkap sehingga perlu adanya alternatif lain untuk memprediksi debit banjir tersebut yaitu dengan menggunakan data hujan TRMM atau PERSIANN dalam mengisi ground data hujan yang tidak ada. Penelitian ini bertujuan untuk mengetahui data hujan satelit yang paling baik (TRMM atau PERSIANN) untuk menentukan debit banjir rencana di lokasi penelitian. Tahap analisis diawali dengan mencari hubungan antara ground data hujan dengan data hujan satelit yang berupa koreksi atau penyesuaian terhadap waktu dan besaran. Penyesuaian terhadap waktu dicari dengan cross correlation, sedangkan penyesuaian terhadap besaran dicari dengan regresi. Tahap analisis selanjutnya adalah menggunakan data hujan satelit yang memiliki korelasi paling baik untuk digunakan dalam analisis perkiraan debit banjir. Hasil penelitian menunjukkan bahwa terdapat hubungan antara ground data hujan dengan hujan satelit TRMM lebih akurat dibandingkan data hujan satelit PERSIANN sehingga prediksi debit banjir untuk kala ulang 2 tahun, 5 tahun, 10 tahun, 20 tahun, 50 tahun, 100 tahun, dan 1000 tahun secara berurutan adalah 11.31 m3/s; 31.76 m3/s;64.68 m3/s; 114.95 m3/s; 214.68 m3/s; 320.55 m3/s; dan 943.77 m3/s.
Kata kunci: hujan terukur permukaan, hujan satelit, regresi, cross correlation, debit banjir rencana.
PENGARUH STRUKTUR PENGENDALIAN INTERNAL, KUALITAS SUMBER DAYA MANUSIA, KELENGKAPAN DOKUMEN ARSIP USAHA DAN FUNGSI MANAJEMEN TERHADAP PERKEMBANGAN USAHA MIKRO KECIL DAN MENENGAH (UMKM) DI KABUPATEN BANYUMAS
Authors: Widianingsih Rini , Bawono Icuk Rangga , Mustafa Rasyid Mei , Nugroho Isman Setyo 
Published: January 2021

Penelitian ini merupakan penelitian studi empiris dengan survei pada UMKM di Kabupaten Banyumas. Tujuan dari penelitian ini adalah untuk mengetahui kondisi struktur pengendalian intern UMKM, mengetahui perkembangan UMKM di Kabupaten Banyumas, mengetahui signifikansi pengaruh struktur pengendalian intern, kualitas sumber daya manusia, kelengkapan dokumen arsip usaha UMKM dan fungsi manajemen terhadap perkembangan usaha UMKM baik secara simultan maupun parsial dan untuk mengetahui variabel yang paling berpengaruh terhadap perkembangan usaha UMKM. Penelitian ini menggunakan analisis regresi berganda. Berdasarkan hasil penelitian diperoleh kesimpulan bahwa struktur pengendalian intern pada UMKM di Kabupaten Banyumas telah memadai. Terdapat perkembangan usaha UMKM di Kabupaten Banyumas dari tahun 2012 sampai dengan tahun 2016. Secara simultan struktur pengendalian intern, kualitas sumber daya manusia, kelengkapan dokumen arsip usaha dan fungsi manajemen berpengaruh signifikan terhadap perkembangan usaha UMKM di Kabupaten Banyumas. Secara parsial kualitas sumber daya manusia dan kelengkapan dokumen arsip usaha berpengaruh signifikan terhadap perkembangan usaha UMKM di Kabupaten Banyumas, sedangkan struktur pengendalian intern dan fungsi manajemen tidak berpengaruh terhadap perkembangan usaha UMKM di Kabupaten Banyumas. Kualitas Sumber Daya Manusia merupakan variabel yang paling berpengaruh terhadap perkembangan usaha UMKM di Kabupaten Banyumas.
ANALISIS MENGENAI PROSTITUSI CYBER BAGI PARA PELAKU DAN BAGI PARA MUCIKARI DI INDONESIA
Authors: Ayu Hanuring , Suparwi  
Published: January 2021

Tujuan penulisan ini untuk mengetahui tentang dasar hukum bagi penyedia jasa prostitusi dan bagi para pelaku prostitusi. Dalam penelitian ini termasuk ke dalam hukum normatif. Penelitian ini menggunakan pendekatan perundang-undangan. Ketentuan di dalam KUHP hanya dapat digunakan untuk menjerat penyedia jasa / germo/muncikari berdasarkan ketentuan Pasal 296, Pasal 297, jo. Pasal 506 KUHP: Orang yang menyediakan jasa pornografi sebagaimana disebutkan dalam Pasal 4 ayat (2) UU Pornografi Nomor 44 tahun 2008. Jika kata-kata atau tulisan dan gambar yang disiarkan oleh pelacur (prostitute) melalui media sosial memuat kecabulan atau eksploitasi seksual yang melanggar norma kesusilaan dalam masyarakat, maka pelacur (prostitute) tersebut dapat saja dijerat dengan Pasal 27 ayat (1) UU Nomor 11 Tahun 2008 tentang ITE jo. Pasal 45 UU Nomor 19 Tahun 2016 Tentang Perubahan UU No 11 Tahun 2008. Jika iklan yang dilakukan oleh pelacur (prostitute) tersebut disertai foto yang mengandung muatan pornografi, maka ia juga dapat dikenai pidana berdasarkan Pasal 8 jo. Pasal 34 UU Pornografi Nomor 44 Tahun 2008. Penegakan hukum tentang prostitusi cyber semakin sulit dilakukan karena ada sebagian masyarakat yang justru mendukung prostitusi cyber dengan menganggapnya sebagai komoditi bisnis. Bahkan ada paradigma pemikiran yang menganggap prostitusi cyber sebagai hal yang wajar dan diharapkan untuk segera dilegalisasikan.
Eksplorasi Kayu Strip Menggunakan Teknik Laminasi dan Bending
Authors: Zamilia Zamilia , Rizki Ista 
Published: January 2021

Artikel ini membahas mengenai penelitian dan eksperimen, bagaimana pengolahan material kayu strip dilakukan, sehingga dapat menjadi sebuah bidang lengkung, dan dijadikan produk kriya interior. Tujuan penelitian dari penggunaan teknik laminasi dan bending pada material kayu strip menjadi produk kayu adalah untuk menambah pengetahuan tentang cara menggunakan teknik laminasi dan bending pada potongan kayu strip sehingga teknik yang digunakan tepat guna dan barang yang dihasilkan memiliki nilai estetik. Target yang akan dicapai dari penelitian ini adalah tutorial cara menggunakan teknik laminasi dan bending pada kayu strip dan penciptaan karya produk dari kedua teknik di atas. Untuk mencapai tujuan penelitian tersebut, metode yang digunakan adalah metode kualitatif dengan cara: studi pustaka, observasi, wawancara, dokumentasi foto, eksperimen teknik dan alat, serta eksplorasi material.