bluuebunny/crossref_metadata_2025_split huggingface dataset:
On band modules and $$\tau $$-tilting finiteness
Authors: Schroll Sibylle , Treffinger Hipolito , Valdivieso Yadira 
Published: May 2021

AbstractIn this paper, motivated by a $$\tau $$
τ
-tilting version of the Brauer-Thrall Conjectures, we study general properties of band modules and their endomorphisms in the module category of a finite dimensional algebra. As an application we describe properties of torsion classes containing band modules. Furthermore, we show that a special biserial algebra is $$\tau $$
τ
-tilting finite if and only if no band module is a brick. We also recover a criterion for the $$\tau $$
τ
-tilting finiteness of Brauer graph algebras in terms of the Brauer graph.
Evaluation of material property estimating methods for n-alkanes, 1-alcohols, and methyl esters for droplet evaporation calculations
Authors: Csemány Dávid , Gujás István , Chong Cheng Tung , Józsa Viktor 
Published: May 2021

AbstractModeling of heat and mass transfer in liquid fuel combustion requires several material properties in a wide temperature and pressure range. The unavailable data are commonly patched with various estimation methods. In this paper, group contribution methods (GCM) and law of corresponding states (LCS) were analyzed for estimating material properties of n-alkanes (up to C10H22 and C12H26), 1-alcohols (up to C10H22O), and methyl esters (up to C19H38O2 and C19H36O2). These were compared to reference data to evaluate their applicability. LCS suggested by Poling et al. provides proper estimation for the acentric factor. GCM of Joback accurately estimates normal boiling point, critical properties, and specific heat capacity of the vapor-phase, the latter was corrected for methanol, however, GCM of Constantinou is more accurate for critical pressure of methyl esters. GCM of Ruzicka is suitable for estimating liquid-phase specific heat capacity. This method was updated for methanol. GCM of Elbro gives a proper estimation for liquid-phase density, while LCS of Lucas estimates vapor-phase viscosity properly. LCS of Chung and the modified Eucken method for vapor-phase and GCM of Sastri for liquid-phase thermal conductivity are appropriate. Considering the gas-phase mutual diffusion coefficient, the method of Fuller provides the best estimation, while LCS methods of Riedel and Chen are suitable for the enthalpy of vaporization at the normal boiling point.
Novel FAP ligands enable improved imaging contrast in sarcoma patients due to FAPI-PET/CT
Authors: Koerber Stefan A. , Finck R. , Dendl K. , Uhl M. , Lindner T. , Kratochwil C. , Röhrich M. , Rathke H. , Ungerechts G. , Adeberg S. , Herfarth K. , Jaeger D. , Debus J. , Haberkorn U. , Giesel F. L. 
Published: May 2021

Abstract
Purpose
A high expression of fibroblast activation protein (FAP) was observed in multiple sarcomas, indicating an enormous potential for PET/CT using 68Ga-radiolabeled inhibitors of FAP (FAPI). Therefore, this retrospective study aimed to evaluate the role of the novel hybrid imaging probe for sarcomas as a first clinical evaluation.

Methods
A cohort of 15 patients underwent 68Ga-FAPI-PET/CT for staging or restaging. The acquisition of PET scans was performed 60 min after administration of 127 to 308 MBq of the tracer. The uptake of 68Ga-FAPI in malignant tissue as well as in healthy organs was quantified by standardized uptake values SUVmean and SUVmax.

Results
Excellent tumor-to-background ratios (> 7) could be achieved due to low background activity and high SUVmax in primary tumors (median 7.16), local relapses (median 11.47), and metastases (median 6.29). The highest uptake was found for liposarcomas and high-grade disease (range 18.86–33.61). A high SUVmax (> 10) was observed for clinically more aggressive disease.

Conclusion
These preliminary findings suggest a high potential for the clinical use of 68Ga-FAPI-PET/CT for patients diagnosed with sarcoma.
Efficacy and safety of the Miethke programmable differential pressure valve (proGAV®2.0): a single-centre retrospective analysis
Authors: Hall Benjamin J. , S. Gillespie Conor , Hennigan Dawn , Bagga Veejay , Mallucci Conor , Pettorini Benedetta 
Published: May 2021

Abstract
Purpose
Achieving decompression without CSF over-drainage remains a challenge in hydrocephalus. Differential pressure valves are a popular treatment modality, with evidence suggesting that incorporation of gravitational units helps minimise over-drainage. This study seeks to describe the utility of the proGAV®2.0 programmable valve in a paediatric population.

Methods
Clinical records and imaging of all patients fitted with proGAV®2.0 valves and Miethke fixed-pressure valves between 2014 and 2019 at our tertiary centre were analysed. Patient demographics, indication for shunt and valve insertion/revision and time to shunt/valve revision were collected. Ventricular linear metrics (fronto-occipital horn ratio (FOHR) and fronto-occipital horn width ratio (FOHWR)) were collected pre- and post-valve insertion. Microsoft Excel and SPSS v24 were used for data collection and statistical analysis.

Results
Eighty-eight proGAV®2.0 valves were inserted in a population of 77 patients (n = 45 males (58%), mean age 5.1 years (IQR: 0.4–11.0 years)). A total of 102 Miethke fixed-pressure valves were inserted over the same time period. Median follow-up was 17.5 months (1.0–47.3). One (1.1%) proGAV®2.0 was revised due to over-drainage, compared to 2 (1.9%) fixed-pressure valves (p > 0.05). ProGAV®2.0 insertion resulted in a significant decrease in the mean number of revisions per patient per year (1.77 vs 0.25; p = 0.01). Overall shunt system survival with the proGAV®2.0 was 80.4% at 12 months, and mean time to revision was 37.1 months, compared to 31.0 months (95%CI: 25.7–36.3) and 58.3% in fixed-pressure valves (p < 0.01). Significant decreases were seen following proGAV®2.0 insertion in both FOHR and FOHWR, by 0.014 (95%CI: 0.006–0.023, p = 0.002) and 0.037 (95%CI: 0.005–0.069, p = 0.024) respectively.

Conclusion
The proGAV®2.0 provides effective decompression of hydrocephalic patients, significantly reduces the number of valve revisions per patient and had a significantly greater mean time to revision than fixed-pressure valves.
A reduction in the sea surface warming rate in the South China Sea during 1999–2010
Authors: Jiang Guo-Qing , Jin Qinjian , Wei Jun , Malanotte-Rizzoli Paola , Gordon Arnold L. , Li Mingting 
Published: May 2021

AbstractThe South China Sea (SCS) experienced a significant reduction in warming rate (− 0.01 °C decade−1, $$p>0.10$$

p
>
0.10

) during 1999–2010 following an accelerated and unprecedented warming (+ 0.15 °C decade−1, $$p<0.01$$

p
<
0.01

) in the last three decades (1970–1998). However, most global climate models of the CMIP5 RCP4.5 scenario failed to capture this SCS warming slowdown. In this study, we identify two drivers through numerical simulations by using a regional high-resolution, ocean–atmosphere coupled climate model: the major variance (75%) in the sea surface warming slowdown could be explained by the strengthened winter monsoon over the SCS, and the minor variance (12%) could be explained by the changes in the upper ocean circulations. The winter monsoon over the SCS is likely linked to the La Niña-like SST pattern in the eastern tropical Pacific, which strengthens the Walker circulation and results in anticyclonic circulation over the northwestern Pacific. This enhanced winter monsoon is the atmospheric driver that slows down the SCS basin-scale warming, while the largest reduction of the warming rate occurs in the northern SCS that can be attributed to the oceanic throughflow via the Luzon Strait. These findings could have important implications for future climate projections over the SCS and adjacent oceans.
Cross-sectional adherence with the multi-target stool DNA test for colorectal cancer screening in a large, nationally insured cohort
Authors: Miller-Wilson Lesley-Ann , Rutten Lila J Finney , Van Thomme Jack , Ozbay A Burak , Limburg Paul J 
Published: May 2021

Abstract
Purpose
Colorectal cancer (CRC) is the second most deadly cancer in the USA. Early detection can improve CRC outcomes, but recent national screening rates (62%) remain below the 80% goal set by the National Colorectal Cancer Roundtable. Multiple options are endorsed for average-risk CRC screening, including the multi-target stool DNA (mt-sDNA) test. We evaluated cross-sectional mt-sDNA test completion in a population of commercially and Medicare-insured patients.

Methods
Participants included individuals ages 50 years and older with commercial insurance or Medicare, with a valid mt-sDNA test shipped by Exact Sciences Laboratories LLC between January 1, 2018, and December 31, 2018 (n = 1,420,460). In 2020, we analyzed cross-sectional adherence, as the percent of successfully completed tests within 365 days of shipment date.

Results
Overall cross-sectional adherence was 66.8%. Adherence was 72.1% in participants with Traditional Medicare, 69.1% in participants with Medicare Advantage, and 61.9% in participants with commercial insurance. Adherence increased with age: 60.8% for ages 50–64, 71.3% for ages 65–75, and 74.7% for ages 76 + years. Participants with mt-sDNA tests ordered by gastroenterologists had a higher adherence rate (78.3%) than those with orders by primary care clinicians (67.2%). Geographically, adherence rates were highest among highly rural patients (70.8%) and ordering providers in the Pacific region (71.4%).

Conclusions
Data from this large, national sample of insured patients demonstrate high cross-sectional adherence with the mt-sDNA test, supporting its role as an accepted, noninvasive option for average-risk CRC screening. Attributes of mt-sDNA screening, including home-based convenience and accompanying navigation support, likely contributed to high completion rates.
How reliable is anamnestic data in predicting the clinical relevance of house dust mite sensitization?
Authors: Englhard Anna S. , Holzer Martin , Eder Katharina , Gellrich Donata , Gröger Moritz 
Published: May 2021

Abstract
Purpose
For perennial inhalant allergens such as house dust mite (HDM), the German guideline on allergen-specific immunotherapy explicitly recommends provocation testing. This procedure is time-consuming, expensive, and potentially dangerous for the patient. Recently it has been discussed whether provocation tests are really necessary for diagnosing allergy to Dermatophagoides species. Thus, our study aimed to analyze the concordance between nasal provocation tests with Dermatophagoides species and anamnestic data.

Methods
We retrospectively analyzed the concordance between patients’ histories including self-reported symptom scores and the results of provocation testing in 471 individuals with proven sensitization to Dermatophagoides species.

Results
248 patients had a positive nasal provocation test (NPT) result to Dermatophagoides species and 223 individuals a negative NPT result. Patients allergic to HSM suffered significantly more often from atopic dermatitis (14% vs. 7%, p = 0.046) and more from asthma (20% vs. 19%, p = 0.851). Moreover, individuals with clinically silent sensitization complained less about nasal secretion (37% vs. 45%, p = 0.244) but significantly more about nasal dryness (46% vs. 34%, p = 0.046) whereas rates of nasal airway obstruction, ocular complaints and sleep quality were comparable in both groups. Allergic patients reported more often perennial (34% vs. 30%, p = 0.374) and location-dependent (39% vs. 31%, p = 0.090) symptoms. However, the discrepant prevalence of atopic dermatitis was the only statistically significant difference between both groups.

Conclusion
Despite slight differences between both patient groups, clinical data are not sufficient to distinguish between silent sensitization and clinically relevant allergic rhinitis to HDM. Therefore, nasal provocation testing remains the gold standard for assessing clinical relevance in patients sensitized to Dermatophagoides species.
The neurophysiological lesson from the Italian CIDP database
Authors: Spina Emanuele , Doneddu Pietro Emiliano , Liberatore Giuseppe , Cocito Dario , Fazio Raffaella , Briani Chiara , Filosto Massimiliano , Benedetti Luana , Antonini Giovanni , Cosentino Giuseppe , Jann Stefano , Mazzeo Anna , Cortese Andrea , Marfia Girolama Alessandra , Clerici Angelo Maurizio , Siciliano Gabriele , Carpo Marinella , Luigetti Marco , Lauria Giuseppe , Rosso Tiziana , Cavaletti Guido , Peci Erdita , Tronci Stefano , Ruiz Marta , Piccinelli Stefano Cotti , Schenone Angelo , Leonardi Luca , Gentile Luca , Piccolo Laura , Mataluni Giorgia , Santoro Lucio , Nobile-Orazio Eduardo , Manganelli Fiore ,   on the behalf of the Italian CIDP Database Study Group
Published: May 2021

Abstract
Introduction
Electrophysiological diagnosis of chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) may be challenging. Thus, with the aim ofproviding some practical advice in electrophysiological approach to a patient with suspected CIDP, we analyzed electrophysiological data from 499 patients enrolled inthe Italian CIDP Database.

Methods
We calculated the rate of each demyelinating feature, the rate of demyelinating features per nerve, the diagnostic rate for upper andlower limb nerves, and, using a ROC curve analysis, the diagnostic accuracy of each couple of nerves and each demyelinating feature, for every CIDP subtype.Moreover, we compared the electrophysiological data of definite and probable CIDP patients with those of possible and not-fulfilling CIDP patients, and by a logisticregression analysis, we estimated the odds ratio (OR) to make an electrophysiological diagnosis of definite or probable CIDP.

Results
The ulnar nerve had the highestrate of demyelinating features and, when tested bilaterally, had the highest diagnostic accuracy except for DADS in which peroneal nerves were the most informative.In possible and not-fulfilling CIDP patients, a lower number of nerves and proximal temporal dispersion (TD) measurements had been performed compared to definiteand probable CIDP patients. Importantly, OR for each tested motor nerve and each TD measurement was 1.59 and 1.33, respectively.

Conclusion
Our findingsdemonstrated that the diagnosis of CIDP may be missed due to inadequate or incomplete electrophysiological examination or interpretation. At the same time, thesedata taken together could be useful to draw a thoughtful electrophysiological approach to patients suspected of CIDP.
Paraganglioma of the cauda equina: a tertiary centre experience and scoping review of the current literature
Authors: Shtaya Anan , Iorga Robert , Hettige Samantha , Bridges Leslie R. , Stapleton Simon , Johnston Francis G. 
Published: May 2021

AbstractCauda equina paragangliomas are rare benign extra-adrenal neuroendocrine tumours arising from the neural crest cells associated with autonomic ganglia. These tumours are often mistaken preoperatively for ependymomas or schwannomas. Patients present with axial or radicular pain with or without neurological deficits. Recurrence, secretory features and length of follow-up are controversial. We conducted a retrospective cohort study of paraganglioma through searching a prospectively maintained histopathology database. Patient demographics, presentation, surgery, complications, recurrence, follow-up and outcome between 2004 and 2016 were studied. The primary aim was to collate and describe the current evidence base for recurrence and secretory features of the tumour. The secondary objective was to report outcome and follow-up strategy. A scoping review was performed in accordance with the PRISMA-ScR Checklist. Ten patients were diagnosed (M:F 7:3) with a mean age of 53.6 ± 5.1 (range 34–71 years). MRI scans revealed intradural lumbar enhancing lesions. All patients had complete microsurgical excisions without adjuvant therapy with no recurrence with a mean follow-up of 5.1 ± 1.4 years. Tumours were attached to the filum terminale. Electron microscopic images demonstrated abundant neurosecretory granules with no evidence of catecholamine production. A total of 620 articles were screened and 65 papers (including ours) combining 121 patients (mean age 48.8 and M:F 71:50) were included. The mean follow-up was 3.48 ± 0.46 (range 0.15–23 years). Back pain was the most common symptom (94%). Cure following surgery was achieved in 93% of the patients whilst 7% had recurrence. Total resection likely results in cure without the need for adjuvant therapy or prolonged follow-up. However, in certain situations, the length of follow-up should be determined by the treating surgeon.
A quantitative SWOT analyses of key aquaculture players in Africa
Authors: Babatunde Adeleke , Deborah Robertson-Andersson , Gan Moodley , Simon Taylor 
Published: May 2021

AbstractAfrica’s contribution to world aquaculture production in 2018 is still insignificant (2,196,600 tons; ~ 2.7%) albeit significantly increasing with larger-scale investments in Egypt (1,561,457 tons), Nigeria (291,233 tons), and Uganda (103,737 tons) producing substantial quantities (91%) of the total fish production from the region. The quantitative SWOT technique and the multi-attribute decision-making method (MADM) were used to determine and compare aquaculture performance in production, technology, market, policies, and framework among Egypt, Nigeria, Uganda, and South Africa. Factors such as the adoption of new technologies used in the formulation and production of aquafeed (i.e., extruded feed and sinking feed), adoption of best farm management practices, commercialization of aquaculture, growing demand-supply gap due to high per capita consumption of fish, and government’s prioritization of aquaculture industry development through the creation of enabling environment for private sector participation were key strengths and opportunities identified among the leading players. The quantified SWOT shows Egypt exhibited aquaculture development strengths and opportunities; Nigeria has aquaculture development opportunities but weak in competitive strengths, while Uganda and South Africa both possess low, competitive strengths and being faced with threats. Capitalizing on the available opportunities and critical success factors of the leading aquaculture players in Africa, this analysis highlights strategic actions that could boost the development of aquaculture in South Africa. The quantified SWOT analysis was used to determine the competitive position of the aquaculture sectors of the compared countries and can be used as a basis for aquaculture policies and roadmaps.
Genome-wide mapping of histone modifications during axenic growth in two species of Leptosphaeria maculans showing contrasting genomic organization
Authors: Soyer Jessica L. , Clairet Colin , Gay Elise J. , Lapalu Nicolas , Rouxel Thierry , Stukenbrock Eva H. , Fudal Isabelle 
Published: May 2021

AbstractLeptosphaeria maculans ‘brassicae’ (Lmb) and Leptosphaeria maculans ‘lepidii’ (Lml) are closely related phytopathogenic species that exhibit a large macrosynteny but contrasting genome structure. Lmb has more than 30% of repeats clustered in large repeat-rich regions, while the Lml genome has only a small amount of evenly distributed repeats. Repeat-rich regions of Lmb are enriched in effector genes, expressed during plant infection. The distinct genome structures of Lmb and Lml provide an excellent model for comparing the organization of pathogenicity genes in relation to the chromatin landscape in two closely related phytopathogenic fungi. Here, we performed chromatin immunoprecipitation (ChIP) during axenic culture, targeting histone modifications typical for heterochromatin or euchromatin, combined with transcriptomic analysis to analyze the influence of chromatin organization on gene expression. In both species, we found that facultative heterochromatin is enriched with genes lacking functional annotation, including numerous effector and species-specific genes. Notably, orthologous genes located in H3K27me3 domains are enriched with effector genes. Compared to other fungal species, including Lml, Lmb is distinct in having large H3K9me3 domains associated with repeat-rich regions that contain numerous species-specific effector genes. Discovery of these two distinctive heterochromatin landscapes now raises questions about their involvement in the regulation of pathogenicity, the dynamics of these domains during plant infection and the selective advantage to the fungus to host effector genes in H3K9me3 or H3K27me3 domains.
The unstable thermoelectric effect in non-stoichiometric Cu2Se during the non-equilibrium phase transition
Authors: Trawiński Bartosz , Łapiński Marcin , Kusz Bogusław 
Published: May 2021

Abstract
The superionic α ↔ β phase transition in Cu1.96Se thermoelectric material is investigated by means of thermal analysis (DSC) and measurements of Seebeck coefficient and electrical conductivity. Results of the DSC measurements with 1–10 K/min heating and cooling rates show that the material is close to the equilibrium phase composition during the transformation. However, the kinetic limitation of the process exists, which is indicated by supercooling. At the beginning of the β → α transition, the most significant kinetic delay was attributed to the nucleation of the α phase. During the phase transformation, the Seebeck coefficient was lower than in a stabilised material (measured with 0.1 K/min heating/cooling rate). During cooling, a decrease from 130 μV/K (in a stabilised measurement) to 7 μV/K (5 K/min cooling rate) was observed. The deviation from the expected values of the Seebeck coefficient was correlated with the difference between the actual and equilibrium phase compositions.

Graphical abstract
Biological activity evaluations of chemical constituents derived from Mongolian medicinal forage plants and their applications in combating infectious diseases and addressing health problems in humans and livestock
Authors: Murata Toshihiro , Batkhuu Javzan 
Published: May 2021

AbstractMongolian nomadic people possess traditional knowledge of wild plants that grow in their areas of habitation. Many of these are forage plants in nature and are consumed by livestock. However, these plants are known to have medicinal and/or toxic properties. To establish a scientific understanding of the plants, and in turn, offer sound knowledge on their applications and effective use, it is essential to collect data pertaining to the chemical constituents of each plant. Therefore, the first objective of this study was to identify and determine the structural constituents of the forage plants that were available to our research group. Furthermore, in an attempt to demonstrate the biological activities of the isolated chemical compounds, we focused on solving some of the social issues affecting Mongolian communities, including protozoan diseases affecting livestock, vectors of infectious diseases, and the general health of humans and their livestock. The results of the chemical constituents derived from Mongolian medicinal plants and their biological activities that were studied in the recent decade are also described herein.
Graphic abstract