bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fairly-Decided Maltreatment Determinations Significantly Reduce Recidivism? A Quasi-experimental Evaluation of a System-Level Intervention Implementation
Authors: Slep Amy M. Smith , Heyman Richard , Mitnick Danielle , Lorber Michael , Nichols Sara , Perkins Daniel 
Published: February 2021

Abstract
Background. This study examined the impact of the implementation of the Field-tested Assessment, Intervention-planning, and Response (FAIR) system for maltreatment determination on two measures recidivism of family maltreatment. Methods. The 10 U.S. Army installations with the largest caseloads participated. Data were collected when Family Advocacy Program staff used the then-in-place system and then the FAIR system. Cases in each system were followed for six months following their abuse determination to measure the probability of subsequent allegations. Additionally, at five installations, alleged victims of partner abuse were recruited into a confidential study in which they anonymously reported on intimate partner violence via telephone. Results. Both studies found that the FAIR system results in decreased recidivism, measured through subsequent formal reports and anonymous victim reports. Conclusions. This study replicates and extends earlier findings that employing the FAIR system can result in decreased family maltreatment re-offense.
Electrical Properties of Silicon Nanowires Schottky Barriers Prepared by MACE&nbsp;at Different Etching Time
Authors: Rouis Ahlem , Hizem Neila , Hassen Mohamed , kalboussi Adel 
Published: February 2021

Abstract
This article focused on the electrical characterization of silicon nanowires Schottky barriers following structural analysis of nanowires grown on p-type silicon by Metal (Ag) Assisted Chemical Etching (MACE) method distinguished by their different etching time (5min, 10min, 25min). The SiNWs are well aligned and distributed almost uniformly over the surface of a silicon wafer. In order to enable electrical measurement on the silicon nanowires device, Schottky barriers were performed by depositing Al on the vertically aligned SiNWs arrays. The electrical properties of the resulting Al/SiNWs diodes were characterized by current voltage (I-V) and capacity voltage (C-V) measurements. Unlike the conventional Schottky diode, symmetrical current-voltage (I-V) characteristics have been observed with a rectification ratio < 4. The metal-semiconductor-metal (M-S-M) model was used to analyze the (I-V) characteristics by including two Schottky barriers at the interface between metal and SiNWs. The electron transport behavior is explained by the thermionic field emission method (TFE) which added the effect of the tunneling current compared to the conventional thermionic emission theory. The capacitance-voltage C-V characteristics of SiNWs depend on the bias voltage showing that the samples have an obvious space charge region. Symmetric behavior also appears in the C –V curves that confirm the MSM model.
Preferential Tumor Localization in Relation to 18F-FDOPA Uptake for Lower-Grade Gliomas
Authors: Tatekawa Hiroyuki , Uetani Hiroyuki , Hagiwara Akifumi , Yao Jingwen , Oughourlian Talia C. , Ueda Issei , Raymond Catalina , Lai Albert , Cloughesy Timothy F. , Nghiemphu Phioanh L. , Liau Linda M. , Bahri Shadfar , Pope Whitney B. , Salamon Noriko , Ellingson Benjamin M. 
Published: February 2021

Abstract
PurposeAlthough tumor localization and 3,4-dihydroxy-6-18F-fluoro-L-phenylalanine (FDOPA) uptake may have an association, preferential tumor localization in relation to FDOPA uptake is yet to be investigated in lower-grade gliomas (LGGs). This study aimed to identify differences in the frequency of tumor localization between FDOPA hypometabolic and hypermetabolic LGGs using a probabilistic radiographic atlas.MethodsFifty-one patients with newly diagnosed LGG (WHO grade II, 29; III, 22; isocitrate dehydrogenase wild-type, 21; mutant 1p19q non-codeleted ,16; mutant codeleted, 14) who underwent FDOPA positron emission tomography (PET) were retrospectively selected. Semiautomated tumor segmentation on FLAIR was performed. Patients with LGGs were separated into two groups (FDOPA hypometabolic and hypermetabolic LGGs) according to the normalized maximum standardized uptake value of FDOPA PET (a threshold of the uptake in the striatum) within the segmented regions. Spatial normalization procedures to build a 3D MRI-based atlas using each segmented region were validated by an analysis of differential involvement statistical mapping.ResultsSuperimposition of regions of interest showed a high number of hypometabolic LGGs localized in the frontal lobe, while a high number of hypermetabolic LGGs was localized in the insula, putamen, and temporal lobe. The statistical mapping revealed that hypometabolic LGGs occurred more frequently in the superior frontal gyrus (close to the supplementary motor area), while hypermetabolic LGGs occurred more frequently in the insula. ConclusionRadiographic atlases revealed preferential frontal lobe localization for FDOPA hypometabolic LGGs, which may be associated with relatively early detection.
Synthesis of 2D-CZTS Nanoplate as Photocathode Material for Efficient PEC Water Splitting
Authors: Mahalakshmi V. , D Venugopal , Ramachandran K. , Ramesh R. 
Published: February 2021

Abstract
Fabrication of economically viable photocathode for hydrogen energy production through solar water splitting is a major research among the scientific community for a decade. P-type compound Cu2ZnSnS4 (CZTS) is very interesting material due to its absorption property, earth-abundant constituents and environmental friendliness that serves as a suitable candidate to act as a photocathode. In the present work, Cu2ZnSnS4 (CZTS) nanoparticles are synthesized by simple one-step chemical method and annealed at 350 °C for three different times (60 minutes, 90 minutes and 120 minutes). The effect of annealing time on the structural, optical and photoelectrochemical properties are investigated. XRD pattern indicates the formation of tetragonal crystal structure and the crystallinity increases according to the annealing time. 2-D nanoplate morphology is obtained for the sample that was annealed for 120 minutes. From the absorption spectra, it was found that the band gap decreases with increase of annealing time. Further, the prepared nanoparticle thin films are used as a cathode for photoelectrochemical water splitting application. Among these, the nanoparticles that are annealed for 120 minutes showed higher photocurrent density when compared to nanoparticles annealed for 60 minutes and 90 minutes.
A Single Nucleotide Polymorphism in an R2R3 MYB Transcription Factor Triggers ms6 (Ames1) Male Sterility in Soybean
Authors: Yu Junping , Zhao Guolong , Li Wei , Zhang Ying , Wang Peng , Fu Aigen , Zhao Limei , Zhang Chunbao , Xu Min 
Published: February 2021

Abstract
Soybean [Glycine max (L.) Merr.] is an important crop providing vegetable oils and proteins. Increasing demand on soy products heightens the urgency of soybean yield improvement. Hybrid breeding with male sterility system is an effective method to improve crop production. Cloning of genic male sterile (GMS) gene combined with biotechnology method can contribute to constructing GMS-based hybrid Seed Production Technology (SPT) to promote soybean performance and yield. In this research, we identified a soybean GMS locus, GmMS6, by combining bulked segregant analysis (BSA)-sequencing and map-based cloning technology. GmMS6 encodes an R2R3 MYB transcription factor, whose mutant allele in ms6 (Ames1) harbors a single nucleotide polymorphism (SNP) substitution, leading to the 76th Leucine to Histidine change in the DNA binding domain. Phylogenetic analysis demonstrates GmMS6 is a homolog of Tapetal Development and Function 1 (TDF1)/MYB35 that is an anther development key factor co-evolved with angiosperm. It has a recently duplicated homolog GmMS6LIKE (GmMS6L), both of which can rescue the male fertility of Arabidopsis homologous mutant attdf1 while GmMS6L76H cannot, denoting that both proteins are functional and L76 is a critical residue for TDF1’s function. However, compared to anther specific expressed GmMS6, GmMS6L is constitutively expressed at a very low level, explaining deficiency of GmMS6 alone causes pollen abortion. Moreover, the expression levels of major regulatory and structural genes for anther development are significantly decreased in ms6, unveiling that GmMS6 is a core transcription factor regulating soybean anther development.
Towards Ubiquitous Data Access Service of 3D Part Library in Cloud Scheme with Host Independence
Authors: Liu Wei , Kong Chuipin , Niu Qiang , Zhou Xionghui 
Published: February 2021

Abstract
Most current part libraries are created and deployed in specific usage environments or CAD platforms, which inevitably brings obstacles in the share and exchange for part information. To reduce repeated development and provide a uniform interface for designers in different sites, a 3D part library in cloud scheme is presented in this paper. Host programs with predetermined specification can access the part data through an adapter according to their customized requests with uniform interfaces, which constructs a ubiquitous service. To realize host independence, the part models are created in a native ACIS modeler, and then they are converted into 3D files in various formats for practical needs, finally these files are imported into CAD systems or other platforms in real designs. The whole framework can be divided into three components, namely, PLS(Part Library Service) provider, PLS adapters and hosts. PLS provider is the kernel of 3D data access service in cloud scheme, while PLS adapters serve as the bridges that connect PLS provider and hosts, and the PLS can be grafted on various applications including current mainstream CAD systems as a plug-in module or run on the websites or even mobile terminals. The PLS provider is deployed and maintained on cloud and users can acquire remote part information within a local ongoing project. In the detailed construction of this part library, diversiform knowledge for part parameters and structures is implanted to define the geometry and rule constraints in the 3D modeling, with which the backstage has the ability of conveniently editing the information in the part library for better upgrade and contrapuntally services. The concept has been implemented within a PaaS framework to provide the ubiquitous 3D part data access, which has been successfully applied in a large number of manufacturing enterprises, and accumulates considerable practical cases.
Bibliometric Keyword Analysis Across Fifteen Years (2004–2018) of Knee Surgery and Related Research Articles
Authors: Jeon Young-Dae , Park Ki-Bong , Ko Sang-Hun , Jang Seong-Min , Han Jung-Won 
Published: February 2021

Abstract
Background: Bibliometric is a branch of library science that uses mathematical and statistical techniques to analyze articles and the ‘keyword’ describes the most important concept of the article among the structure of the articles of journal. There was no bibliometric analysis that only analyzed the keywords of articles published in a specific single journal focusing on knee-related surgery. The authors analyzed the keywords of the articles published in the Knee Surgery and Related Research (KSRR), which is an official journal of the Korean Knee Society for the last 15 years to identify popular research topics in the field of knee.Methods: Of the 622 articles published in the KSRR from 2004 to 2018, 424 original articles were analyzed and a total of 1,703 keywords were extracted. The authors selected and classified ‘keyword categories’ to comprehensively analyze each keyword describing the same research topic. Among them, the authors selected the top 20 keywords and analyzed research concepts using related keywords. Keywords were classified by publication year to analyze the frequency and tendency of the keywords used in each study.Results: The frequency of use of the top 20 keywords accounted for 48.2% of the keywords used in the journal for the last 15 years. Excluding the keyword “knee”, which represents the affected joint, the top 5 keywords most commonly used were “total knee arthroplasty (TKA)”, “osteoarthritis”, “anterior cruciate ligament reconstruction”, “meniscus”, and “navigation”. The top 5 keywords used together with “TKA”, were “navigation”, “infection”, “management of posterior cruciate ligament”, “transfusion”, and “revision”.Conclusions: We conducted bibliometric research for the KSRR across a 15-year span. The results help define an overall command of the latest topics in knee research and provide insight for launching new projects.
Body Mass Index and Leptin Levels in Serum and Cerebrospinal Fluid in Relation to Delayed Cerebral Ischemia and Outcome after Aneurysmal Subarachnoid Hemorrhage
Authors: Veldeman Michael , Weiss Miriam , Simon Tim Philipp , Hoellig Anke , Clusmann Hans , Albanna Walid 
Published: February 2021

Abstract
ObjectiveAneurysmal subarachnoid hemorrhage (SAH) is associated with a high mortality rate and may leave surviving patients severely disabled. After the initial hemorrhage, clinical outcome is further compromised by the occurrence of delayed cerebral ischemia (DCI). Overweight and obesity have previously been associated with protective effects in the post-bleeding phase. The aim of this study was to assess the effects of patient’s body mass index (BMI) and leptin levels on the occurrence of DCI, DCI-related cerebral infarction and clinical outcome. METHODS263 SAH patients were included of which leptin levels were assessed in 24 cases. BMI was recorded along disease severity documented by the Hunt and Hess and modified Fisher scales. The occurrence of clinical or functional DCI (neuromonitoring, CT Perfusion) was assessed. Long-term clinical outcome was documented after 12 months (extended Glasgow outcome scale). RESULTSA total of 136 (51.7%) patients developed DCI of which 72 (27.4%) developed DCI-related cerebral infarctions. No association between BMI and DCI occurrence (P=.410) or better clinical outcome (P=.643) was identified. Early leptin concentration in serum (P=.258) and CSF (P=.159) showed no predictive value in identifying patients at risk of unfavorable outcome. However, a significant increase of leptin levels in CSF occurred from 326.0 pg/ml IQR 171.9 prior to DCI development to 579.2 pg/ml IQR 211.9 during ongoing DCI (P =.049). CONCLUSIONSIn our data, no association between obesity and clinical outcome was detected. After DCI-development, leptin levels in CSF increased either by an upsurge of active transport or disruption of the blood-CSF barrier.Trial registration: This trial has been registered at ClinicalTrials.gov (NCT02142166) as part of a larger scale prospective data collection. BioSAB: https://clinicaltrials.gov/ct2/show/NCT02142166
The Significance of KL-6 as Prognosis Monitoring Biomarker in Patients With Severe COVID-19 From Stabilized Stage Toward Convalescence
Authors: He Long , Lu Liu , Zong Ming , Zhou Huang , Wang Lan , Chen Nian Zhen , Yuan Jia Yi , Jiang Er Peng , Zheng Liang , Li Qiang , Fan Lie Ying , Liu Zhong Min 
Published: February 2021

Abstract
Background: This study aims to identify some biomarkers for monitoring the recovery of lung injury in severe COVID-19 patients from stabilized stage toward convalescence.Methods: We enrolled participants who diagnosed with severe COVID-19 (n = 28) and health volunteers (n = 25) from Taikang Tongji (Wuhan) Hospital. The patients were in a stabilized stage and had a course of 48.1±12.8 days. We followed these patients for 90 days. The blood routine, cytokines (IL-1β, IL-2, IL-4, IL-5, IL-6, IL-10, IL-12p70, IL-17A, TNF-α, IFN-α, IFN-γ), type II alveolar epithelium injury indicators (Surfactant protein A (SP-A), Krebs von den Lungen-6 (KL-6)) and chest CT were tested on the 1, 30, 60, and 90 days after enrollment. Results: In stabilized stage, the parameters of blood routine and some cytokines (IL-1β, IL-2, IL-4, IL-12p70, TNF-α) had bounced back to normal (p>0.05). Some cytokines (IL-5, IL-6, IL-10, IL-17A, IFN-α, IFN-γ) and type II alveolar epithelium injury indicators (SP-A and KL-6) were still higher than normal (p<0.05). During the stabilized stage to convalescence, in spite of the variation of monocyte count, monocyte/lymphocyte ratio, IL-5, IL-10, IL-12p70, IL-17A, IFN-γ, IFN-α, SP-A and KL-6 were downward trend (p<0.05), only KL-6 level (p<0.05) could simultaneously reflect the lung injury volume which be measured by CT. Conclusions: Our preliminary data indicated that KL-6 could be an effective prognostic biomarker for monitoring the recovery of lung function in patients with severe COVID-19 from stabilized stage toward convalescence.
The Psychometric Properties Persian Version of the Hearing Handicap Inventory Screening Version (HHIE-S) Among Older Adults
Authors: Behboodi Leila , Chattu Vijay Kumar , Adelirad Fatemeh , Heizomi Heleh , Asghari-Jafarabadi Mohammad , Allahverdipour Hamid 
Published: February 2021

Abstract
Background: There is a great need for a valid hearing loss measurement tool in the Persian language to help identify hearing handicap and potential communicational difﬁculties among Persian speaking older adults. The present study was aimed to validate and adapt the original English version of Hearing Handicap Inventory for the Elderly (HHIE) into Persian language.Methods: A cross-sectional study was designed and data was collected from August to November 2019 in Tabriz, Iran among the older adults aged 60 years and above whose hearing loss had been confirmed by audiometry. Self-reporting and face-to-face interviews were the data collection methods in this study. The statistical analysis was performed using SPSS 26.0 (SPSS and STATA 14).Results: An exploratory factor analysis of data resulted in two factors, which included 9 of the 10 items and accounted for 87.00% of the variance. Cronbach’s alpha coefficient (0.85) and the test–retest reliability score (0.73) indicated good internal consistency.Conclusions: The results showed that HHIE-S is a valid and reliable tool for assessing hearing handicap among Persian speaking and Iranian older adults.
Serial Lipocalin 2 and Oncostatin M levels reflect inflammation status and treatment response in axial spondyloarthritis
Authors: Tsui Florence W.L. , Lin Aifeng , Sari Ismail , Zhang Zhenbo , Tsui Hing Wo , Inman Robert D. 
Published: February 2021

Abstract
Background: Informative serum biomarkers for monitoring inflammatory activity and treatment responses in axial spondyloarthritis (axSpA) are lacking. We assessed whether Lipocalin 2 (LCN2) and Oncostatin M (OSM), both have roles in inflammation and bone remodeling, may accurately reflect chronic inflammation and treatment response in axSpA. Previous reports in animal models showed involvement of LCN2 and OSM in gut inflammation. We asked whether they also play a role in human axSpA.Methods. Analysis of a longitudinal observational axSpA cohort (286 patients) with yearly clinical assessments and concurrent measurements of serum LCN2 and OSM (1204 serum samples) for up to 12 years. Biomarkers levels were correlated with MRI scoring and treatment response. Results. Persistent and transient elevation of LCN2 and OSM were observed in axSpA patients. Persistent elevation of LCN2 or OSM, but not CRP, was correlated with sacroiliac joint MRI SPARCC scores (Pearson’s correlation p = 0.0005 and 0.005 for LCN2 and OSM respectively). We observed both concordant and discordant patterns of LCN2 and OSM in relationship to back pain, the cardinal clinical symptom in axSpA. 26% (73/286) of the patients remained both clinically and serologically active (CASA). 14% (40/286) of them remained clinically active with back pain, but were serologically quiescent (CASQ). 60% (173/286) of the patients became clinically quiescent, with back pain resolved, but 53% (92/173) of them were serologically active (CQSA). With respect to treatment responses, transient elevation of LCN2 or OSM over time was predictive of better response to all treatments. The data suggest that failure to normalize LCN2 and OSM indicates persistent chronic inflammation, as reflected by positive MRI imaging of the sacroiliac joints. Prevalence of severe ankyloses is comparable in CQSA and CASA patients, indicating that disease progresses even when back pain may be controlled (CQ)Conclusion. In axSpA, persistent LCN2 and/or OSM elevation reflects chronic SIJ inflammation and suboptimal treatment response. In our cohort, half of the currently deemed clinically quiescent patients with back pain resolved, continued to demonstrate chronic inflammation. LCN2 and OSM profiling outperforms CRP as a predictive measure and provides an objective assessment of chronic local inflammation in axSpA patients.
Sexual Needs and Sexual Health in the Elderly Population in Eastern China: Findings From a Cross-Sectional Study
Authors: xie tiansheng , Yan Haibo , Wang Guohua , Jiang Guojun 
Published: February 2021

Abstract
Objective: To investigate the sexual activity of older adults, to understand their knowledge attitude and practice(KAP) regarding sexually transmitted diseases (STD) and to perform correlation analyses of STD symptoms in this population.Methods: A cross-sectional study was conducted among 585 subjects from counties in eastern China. Data was collected from unified questionnaires; descriptive statistics were used for demographic characteristics and sexual activity, which used student t test, to compare the different groups, and multivariate logistic regression analysis to identify the dependence of influential factors.Results: 24.62% of participants were reported as sexually active. The subjects still work and the main income from personal salary was higher than other individuals . Furthermore, when participants monthly income or expenses was more than 1000 RMB, they seemed to have a higher sexual activity. Gender and monthly income were dependent on influential factors related to sexual activity. 54.7% showed good awareness of STD, but only 7.96% of them consistently and correctly used condoms; moreover, 21.03% report to have previously suffered from any STD symptoms. Sexual behavior, use of condoms and commercial sexual behavior were dependent on influential factors of sexual activity.Conclusions: Sexual needs and sexual health of older adults should not be neglected, effective strategies should be drafted for such population.