bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pneumatocele Induced Pneumothorax in a patient with Post-COVID-19 Pneumonitis. A Case Report
Authors: Wortman II Kevin O. , Wortman Kevin O. 
Published: August 2021

Background: The COVID-19 pandemic has been challenging medical professionals and facilities for over a year now. Much of the literature describes pathologic lung changes and complications associated with SARS-CoV-2, with pneumothorax and pneumatoceles not being uncommon.
The Case: We describe a case involving a patient that presented to the emergency department with a pneumothorax. Three weeks prior, the patient was hospitalized for 10 days in acute respiratory distress secondary to COVID-19 pneumonitis, which did not require ventilator support. Follow up imaging revealed a 7 cm (AP) x 4.6 cm (transverse) x 2.5 (cc) cm pneumatocele.
Conclusion: We speculate that antecedent rupture of an unrecognized pneumatocele likely caused lung collapse leading to the patient’s pneumothorax. This review delves into the etiology of both pneumothoraces and pneumatoceles along with their relation to COVID-19 pneumonia.
Existências e Resistências negras em dias de ódio
Authors: Paixão Cassiane de Freitas 
Published: August 2021

O texto trata da fala da conferência de abertura do Forum Sociedade Critica e trata de pensar sobre as resistências negras ao longo do século 20. Iniciamos o texto com alguns questionamentos sobre a conjuntura de ódio e de violência com relação à população negra no Brasil, discutindo e refletindo sobre algumas questões pontuais. Posteriormente analisamos o quanto as resistências negras se fizeram presentes e pautaram já na segunda metade do século questões políticas, econômicas e sociais que vao incidir tanto na Constituição de 1998, quanto em leis e processos de combate ao racismo no inicio do século 21, como o Estatuto da Igualdade Racial, a Lei 10639, entre outras. Por fim, o ensaio busca pensar que é necessário ocupar espaços políticos (aqueles que denotam relações de poder) nos mais diferentes âmbitos, e que essa é uma luta coletiva para as futuras gerações.
Contribution à l’amélioration des pratiques de soins essentiels aux nouveau-nés dans le centre de communautaire et universitaire (CSCom U) de Konobougou
Authors: Coulibaly D 
Published: August 2021

Introduction : La période postnatale immédiate est une étape fondamentale d’adaptation physiologique et psychologique pour le nouveau-né. La plupart des difficultés d'adaptation à la vie extra-utérine sont prévisibles et doivent être anticipées. Le but de cette étude était de contribuer à l’amélioration des pratiques de soins essentiels aux nouveau-nés dans le centre de santé communautaire et universitaire (CSCom-U) de Konobougou. Matériel et méthodes : Il s’agissait d’une étude de recherche action qui s’est déroulée dans la maternité du CSCom U de Konobougou dans le district sanitaire de Barouéli/Région de Ségou du 01 décembre 2020 au 31 janvier 2021. Nous avons introduit dans cette étude 32 mères et 8 agents de santé. Résultats : Les matrones étaient plus représentées avec 62,5% suivies des sages-femmes avec 25%. Avant l’enquête tous les matériels étaient disponibles sauf la sonde naso-gastrique. Suite à notre recommandation l’équipe a décidé de s’en procurer une, ce qui a permis de porter la disponibilité des matériels à 100%. A la phase initiale de l’étude, 25% des mères enquêtées avaient reçu des consignes sur les soins du cordon ombilical, suite à la mise à niveau des prestataires nous avons obtenu une augmentation de 75% à la phase finale soit 100%. Conclusion : Les soins essentiels du nouveau-né restaient insuffisants pour déficit de formation initiale et/ou conti­nue d’une part et pour instabilité du personnel d’autre part. Ainsi, nous avons recommandé une mise en place de programme de formation continue et de suivi-évaluation destiné aux prestataires.
Mots clés : Soins essentiels, nouveau-nés, centre de communautaire et universitaire, Konobougou
Aspects épidémio-cliniques de la drépanocytose chez l’enfant à l’hôpital Nianankoro Fomba de Ségou
Authors: Bah A 
Published: August 2021

Introduction : L’objectif était d’étudier les aspects épidémio-cliniques de la drépanocytose chez l’enfant à l’hôpital Nianankoro Fomba (HNF) de Ségou. Methodologie : Il s’agissait d’une étude descriptive transversale allant du 02 janvier 2019 au 28 février 2020 au service de pédiatrie de l’HNF de Ségou. Elle a porté sur tous les cas documentés de drépanocytose chez les enfants de 1 mois à 15 ans, et ceux dont le statut a été confirmé dans le service durant la période d’étude. Les variables étudiées étaient : les caractéristiques sociodémographiques, cliniques, biologiques et thérapeutiques des malades. Les données ont été saisies et analysées sur le logiciel Epi info version 3.5.4. Résultats : Pendant l’étude 7617 patients ont consulté dans le service dont 105 cas de drépanocytose soit une fréquence hospitalière de 1,3%. L’âge moyen des enfants était de 53,64 mois±4ans. Le sex ratio était de 1,4 en faveur des garçons. La notion de consanguinité était retrouvée dans 51,43% des cas. La pâleur cutanéo- muqueuse était le signe physique le plus fréquent avec 83,81%; le phénotype SS de l’hémoglobine représentait 92,38%; la crise vaso- occlusive était la complication aiguë la plus fréquente avec 51,43%. Le taux de létalité était de 0,95%. Conclusion : La drépanocytose est fréquente dans le service de pédiatrie de l’HNF- Ségou avec 1,3%. La prise en charge est difficile du fait du faible niveau du plateau technique et du faible niveau socioéconomique des parents.
Mots clés : Drépanocytose - Enfant - Ségou
Case report: MPN-eo with balanced rearrangement of MPRIP-PDGFRB t(5;17)(q32;p11), responding to low dose imatinib
Authors: Beel Karolien , Ameye Geneviève , Kelver Wim De , Michaux Lucienne 
Published: August 2021

We present a young patient with a rare eosinophilic myeloproliferative neoplasm MPN-eo with a balanced rearrangement of MPRIP-PDGFRB t(5;17)(q32;p11). This fusion gene was reported in only one other case in 2015. A personalized molecular test was developed with the diagnostic material of the patient. Our patient is in complete cytogenetic and molecular remission under low dose imatinib, two years after treatment initiation.
Using a research coach to enhance evidence-based practice integration in undergraduate nursing
Authors: D'Souza Melba Sheila 
Published: August 2021

Background and objective: Coaching contributes to the understanding and application of knowledge in nursing practice. This study aims to examine the implementation of a research coach to enhance evidence-based practice integration in undergraduate nursing.Methods: Design: This study used a quasi-experimental non-equivalent post-test-only design. Settings and participants: Forty second-year undergraduate nursing students were invited to participate in the study at a public university in 2019. Methods: The evidence-based practice (EBP) questionnaire was used, and the primary outcomes were attitudes, skills, and capabilities of EBP. The undergraduate students worked with a third-year level research coach to engage in evidence-based nursing using clinical case studies. Results: The findings expressed the students’ readiness to capture, select, and organize their critical thinking skills through case studies and online discussion. Students perceived that they needed versatile skills in the interpretation and application of evidence-based nursing.Conclusions: A research coach played an essential role for novice student nurses in improving decision-making skills and transition to practice in this setting. The research coach model enables critical thinking and problem-solving skills through interaction and case studies.
Comparative study between synthetic and dairy wastewaters in single chamber microbial fuel cell for power generation
Authors: Choudhury Payel , Majumdar Ria , Bandyopadhyaya Tarun Kanti 
Published: August 2021

To investigate the performance of microbial fuel cell (MFC) with a single-chamber membrane, Pseudomonas aeruginosa is used as a bio catalyst for various synthetic wastewaters rich in carbohydrate and is compared with real dairy wastewater in this experiment. Therefore, the choice of appropriate carbon, nitrogen, NaCl, inoculum content, temperature, and pH process parameters are used for preparing synthetic wastewater was agreed upon by one-variable-at-a time approach. Maximum levels of voltage generation attained from the synthetic wastewater was 485 mV when supple­mented with 1.5 % of lactose as a source of carbon, 0.3 % of ammonium chloride as a decent nitrogen source, 0.03 % of NaCl, inoculum concentration of 3 %, the temperature at 37 oC and pH 7. On the other hand, the maximum voltage attained with real dairy wastewater was 561 mV with high chemical oxygen demand (COD) value of 801 mg l-1. The maximum power density obtained from dairy wastewater was 73.54 mW m-2. Thus, High voltage achieved for MFC operating with real dairy wastewater suggests that it can be used not only for the industrial application to generate more renewable power, but also for the wastewater treatment carried out at the same time.
Study of Plasminogen Activator Inhibitor-1 (PAI-1) as Prognostic Marker in Sepsis
Authors: Elnomany Amal Abdelaziz Abdellatif , Hodeib Hossam Abd El Mohsein , Elbaradey Ghada Fouad , Sweilam Mohammad Abdelrahman 
Published: August 2021

Background: Sepsis is an unorganized host response to infection that is manifested by the failure of organs and DIC and systemic coagulation due to failure of Plasmin as an important fibrin lytic protein that is regulated by plasminogen activators and inhibitors. Our theory is that elevated PAI-1 may have a role in multi-system organ failure in patients with septicemia and systemic coagulopathy.
Aim: to evaluate plasminogen activator inhibitor-1 as a prognostic factor in patients with septicemia and DIC.
Patients and Methods: 60 cases with septicemia and in shock, in addition to 20 healthy individuals. Cases were selected from surgical ICU, Tanta University hospitals. Normal healthy subjects were matched by age and gender with the patients' group.
Results: Respiratory system and urinary tract infections, were the most common infections and high SOFA and APACHE scores in the selected cases. The hematological findings in septic patients are anemia, thrombocytopenia, and leukocytosis. There was a significant increase in urea, creatinine, SGOT, SGPT levels, and CRP in patient groups. Higher levels of PAI-1 in cases suffering sepsis. An increased mortality rate after 28 days of follow-up was noticeable in cases with established septic shock compared to other patient groups in Tanta university surgical intensive care. We found a direct correlation between PAI-1and SOFA, APACHE, bilirubin, creatinine, PT, APTT, and Procalcitonin.
Conclusions: PAI-1 level has a prognostic value in cases with infections or septicemia presented to our emergency center.
Comparison of Efficacy of 4% Articaine and 0.5% Bupivacaine and 2% Lignocaine Anaesthetic agents in Orthodontic Extractions-A Prospective Randomised Controlled Study
Authors: Srinivasulu Yandeti , Wahab Abdul , Murugan P. Senthil 
Published: August 2021

Aim: Articaine, bupivacaine, lignocaine are amide type of local anesthetic agents, which are of almost equal potency. However, lidocaine is considered the gold standard and is the most widely used anesthetic agent because of its potency, safety, and efficiency. Articaine is fast acting and bupivacaine is long lasting local anaesthesia. The aim of this clinical study was to evaluate and compare the clinical anesthetic efficacy of 4% articaine and 0.5% bupivacaine and 2% lignocaine in therapeutic orthodontic extractions.
Materials and Methods: A 150 healthy patients, requiring Maxillary premolars extraction for orthodontic reasons were included. Patients were categorized into three groups (4% articaine and 0.5% bupivacaine, 2% lignocaine) in a crossover manner. Subjective and objective observations recorded that include age, gender, and pain score using visual analog scale. At the first appointment, both upper premolars were extracted on one or two sides of the jaws. Each patient was evaluated using a visual analogue scale.
Results: The results showed that 0.5% Bupivacaine had significantly faster onset of action and lower visual analogue scores when compared with articaine and lignocaine. However, the duration of analgesia and need of first rescue analgesic medication was longer in the bupivacaine group.
Conclusion: Within the limitations of study we found that Bupivacaine has the best anaesthetic effect with low pain scores followed by Articaine and followed by Lignocaine. Bupivacaine is an alternative local anaesthetic drug for performing therapeutic orthodontic extractions.
Improved Efficacy and Stability of Silymarin Loaded Nanocochleates Over Liposomes for the Treatment of Skin Diseases
Authors: Rub Rukhsana , Munot Neha , Wadate Akshay 
Published: August 2021

Aim: Silymarin, a complex polyphenolic component mixture with anti-oxidant, anti-inflammatory, and membrane-stabilizing property is being investigated in several dermatological conditions. Present research aims to evaluate potential of silymarin loaded nanocochleates and liposomal topical application for treating chronic skin diseases.
Study Design: Silymarin loaded liposomes and nanocochleates were formulated and optimized using Design Expert software. Different invitro and exvivo tests were performed to compare their performance.
Place and Duration of Study: The study was conducted in Smt. Kashibai Navale College of Pharmacy, Pune, India, between January 2019 till February 2020.
Methodology: Liposomes were prepared using ethanol injection method and further treated with calcium chloride to form nanocochleates by trapping method. Design of experiments (32 Factorial Design) was used for optimization of nanocochleates. Cell line studies (HaCaT cell lines) and short term stability studies were performed to compare the efficacy and stability respectively.
Results: Particle size, entrapment efficiency and drug deposition in Wistar Rat Skin was found to be statistically significant for nanocochleates over liposomes proving superiority of cochleates. Both the carriers sustained release of silymarin for 24h. Antimicrobial efficacy of nanocochleates against E.coli and S.aureus was significant. Inhibition of hyper proliferation of HaCaT cell lines (key mechanism by which most of the antipsoriatic drugs act) demonstrated the superiority of nanocochleates over liposomes.The nanocochleates also displayed better stability compared to liposomes due to decreased entrapment efficacy and leakage of drug.
Conclusion: Silymarin loaded Nanocochleates could prove as a promising topical drug delivery system for the treatment of chronic skin diseases like psoriasis.
Analysis of Accommodation Gain of Presbyopia Eye After Laser Ablation (or Shrinkage) of Sclera Via Lens Reshaping and Lens Anterior Shift
Authors: Lin Jui-Teng 
Published: August 2021

Purpose: To derive and provide analytic formulas for an accommodative gain of presbyopia eyes. via sclera ablation and/or thermal shrinkage such that the lens is reshaped and/or its position is shifted. New mechanisms are also proposed.
Study Design: To increase the accommodation of presbyopia.
Place and Duration of Study: New Taipei City, Taiwan, between June 2021 and July 2021.
Methodology: Accommodation gain is calculated by a 4-component theory, in which the rate functions are derived by an effective eye model for the change of anterior curvature of the lens and its anterior shift. The measured data of accommodative response of the lens versus the lens curvature change and anterior shift are analyzed. The measured net change of the posterior vitreal zonules (PVZ) length and the space between the ciliary body and lens (CLS) during the accommodation are also analyzed.
Results: The accommodative gain (AG) is mainly due to the change of lens anterior curvature and its anterior shift. The AG per diopter change of the reshaped lens is 0.62 to 0.68 by our formulas, comparing to the measured average value M'=0.69.The efficacy of LASA (or AG) is proportional to the amount of scleral tissue removed (or shrinkaged), such that more space is produced for the change of PVZ and CLS from a UCS to AS for accommodation.
Conclusion: The AG is proportional to the amount of scleral tissue removed (or shrinkaged), such that more space is produced for the change of PVZ and CLS from a UCS to AS for accommodation.
A Novel Synthetic Nano-Catalyst (Ag2O3/Zeolite) for High Quality of Light Naphtha by Batch Oxidative Desulfurization Reactor
Authors: Nawaf Amer Talal , Hameed Shymaa Ali , Abdulateef Layth T. , Jarullah Aysar Talib , Kadhim Mohammed S. , Mujtaba Iqbal M. 
Published: August 2021

Oxidative desulfurization process (ODS), enhanced with a novel metal oxide (Ag ions) as an active component over nano-zeolite that has not been reported in the literature, is used here to improve the fuel quality by removing mercaptan (as a model sulfur compound in the light naphtha). Nano-crystalline (nano-support (Nano-zeolite)) composite is prepared by Incipient Wetness Impregnation method loaded with a metal salt to obtain 0.5, 1 and 1.5% of Ag2O3 over Nano-zeolite. The new homemade nano-catalysts (Ag2O3/Nano-zeolite) prepared are characterized by Brunauer–Emmett–Teller (BET) (surface area, pore volume and pore size), X-ray Diffraction (XRD), Fourier Transform Infra Red (FTIR), and Scanning Electron Microscopy (SEM) analysis. The ODS process is then used to evaluate the performance of the catalysts for the removal of sulfur at different reaction temperatures (80–140 °C) and reaction times (30–50 min) in a batch reactor using the air as oxidant. 87.4% of sulfur removal has been achieved using 1% silver oxide loaded on Nano zeolite (1% of Ag2O3/Nano-zeolite) giving a clear indication that our newly designed catalyst is highly efficient catalyst in the removal of sulfur compound (mercaptan) from naphtha. A new mechanism of chemical reaction for sulfur removal by oxygen using the new homemade catalyst (Ag2O3/Nano-zeolite) prepared has been suggested in this study. The best kinetic model parameters of the relevant reactions are also estimated in this study using pseudo first order technique based on the experimental results. Copyright © 2021 by Authors, Published by BCREC Group. This is an open access article under the CC BY-SA License (https://creativecommons.org/licenses/by-sa/4.0).
Proline‐rich extensin‐like receptor kinases PERK5 and PERK12 are involved in pollen tube growth
Authors: Borassi Cecilia , Sede Ana R. , Mecchia Martín A. , Mangano Silvina , Marzol Eliana , Denita‐Juarez Silvina P. , Salgado Salter Juan D. , Velasquez Silvia M. , Muschietti Jorge P. , Estevez José M. 
Published: August 2021

Proline‐rich extensin‐like receptor kinases (PERKs) belong to the hydroxyproline‐rich glycoprotein (HRGP) superfamily known to be involved in many plant developmental processes. Here, we characterized two pollen‐expressed PERKs from Arabidopsis thaliana, PERK5 and PERK12. Pollen tube growth was impaired in single and double perk5‐1 perk12‐1 loss of function mutants, with an impact on seed production. When the segregation was analysed, a male gametophytic defect was found, indicating that perk5‐1 and perk12‐1 mutants carry deficient pollen transmission. Furthermore, perk5‐1 perk12‐1 displayed an excessive accumulation of pectins and cellulose at the cell wall of the pollen tubes. Our results indicate that PERK5 and PERK12 are necessary for proper pollen tube growth, highlighting their role in cell wall assembly and reactive oxygen species homeostasis.
Nonlinear partial differential equation modeling and adaptive fault‐tolerant vibration control of flexible rotatable manipulator in three‐dimensional space
Authors: Wang Jiacheng , Cao Fangfei , Liu Jinkun 
Published: August 2021

SummaryIn this article, we investigate the problem of nonlinear modeling and adaptive boundary vibration control with actuator failure for a flexible rotatable manipulator in three‐dimensional space, which is made up of a rotatable base and a flexible manipulator. In order to accurately reflect the characteristics of the distributed parameters, the Hamilton principle is introduced to derive the dynamic model expressed by partial differential equations (PDEs). Based on the model, an innovative boundary control scheme is proposed to eliminate the deflection and vibration simultaneously, and to guarantee that the rotatable base and the flexible manipulator can track the desired angle respectively. The adaptive law is developed to estimate the loss of the actuator. The effectiveness of the designed controller is verified from both theoretical analysis and numerical simulation.
Long‐Distance Triplet Diffusion and Well‐Packing Hosts with Ultralow Dopant Concentration for Achieving High‐Efficiency TADF OLED
Authors: Chen Chia‐Hsun , Ding Wen‐Cheng , Lin Bo‐Yen , Huang Jau‐Jiun , Leung Man‐kit , Lee Jiun‐Haw , Chiu Tien‐Lung 
Published: August 2021

AbstractHigh‐efficiency organic light emitting diodes (OLEDs) are fabricated using a group of benzimidazole‐carbazole derivatives with good molecular packing as hosts. The hosts are separately doped with a green thermally activated delayed fluorescence (TADF) emitter, 1,2,3,5‐tetrakis(carbazol‐9‐yl)‐4,6‐dicyanobenzene (4CzIPN). An ultralow concentration (0.5% volume ratio) of 4CzIPN is required in the emitting layer (EML) to achieve a record‐high external quantum efficiency of 31.8% by comparison with reported 4CzIPN‐relative devices. This result is attributed to efficient energy transfer, alleviation of concentration quench of 4CzIPN, long‐distance triplet exciton diffusion ability of host materials, and excellent horizontal molecular packing. With an increase in dopant concentration from 0.5% to 15%, the diodes exhibit a tiny variation in power efficiencies (82.9−78.7 lm W−1) and current efficiencies (92.2−87.5 cd A−1). In particular, the long‐distance triplet exciton diffusion ability of hosts exceeds the typical distance limitation (less than 10 Å) of Dexter energy transfer. Thus, high‐efficiency OLEDs are obtained with the scarce dopants . The aforementioned long‐distance triplet diffusion results are verified by the almost‐identical high‐efficiency device performances and the longer delayed emission lifetime in transient electroluminescence signals of a series of partially doped devices, conducting by separately doping low‐concentration TADF emitters in different EML regions.
Intramolecular Diels‐Alder Reaction of Styrene with Phenoxy‐Acrylate for Construction of Functionalized Naphthalenes
Authors: Pan Liu‐Na , Wang Qin , Sun Jing , Yan Chao‐Guo 
Published: August 2021

AbstractThe DABCO promoted domino reaction of 1‐(2‐hydroxyphenyl)‐3‐phenylprop‐2‐en‐1‐ones and alkyl propiolate or dialkyl but‐2‐ynedioate in toluene at high temperature resulted in methyl 3‐(2‐hydroxybenzoyl)‐1‐naphthoates or dimethyl 3‐(2‐hydroxybenzoyl)naphthalene‐1,2‐dicarboxylate in moderate to good yields. The hydroxyl group played a crucial rule in the reaction. The reaction mechanism of this formal [4+2] cycloaddition reaction was believed with initially formation of methyl 3‐(2‐cinnamoylphenoxy)acrylate, intramolecular Diels‐Alder reaction, ring‐opening of benzo[b]xanthene and aromatization process.