bluuebunny/crossref_metadata_2025_split huggingface dataset:
A longitudinal change of syndecan-1 predicts risk of acute respiratory distress syndrome and cumulative fluid balance in patients with septic shock: a preliminary study
Authors: Kajita Yuka , Terashima Tsuguaki , Mori Hisatake , Islam Md. Monirul , Irahara Takayuki , Tsuda Masanobu , Kano Hideki , Takeyama Naoshi 
Published: April 2021

Abstract
Background
The purpose of this study is to investigate the time course of syndecan-1 (Syn-1) plasma levels, the correlation between Syn-1 and organ damage development, and the associations of Syn-1 level with cumulative fluid balance and ventilator-free days (VFD) in patients with septic shock.

Methods
We collected blood samples from 38 patients with septic shock upon their admission to ICU and for the first 7 days of their stay. Syn-1 plasma level, acute respiratory distress syndrome (ARDS), other organ damage, VFD, and cumulative fluid balance were assessed daily.

Results
Over the course of 7 days, Syn-1 plasma levels increased significantly more in patients with ARDS than in those without ARDS. Patients with high levels of Syn-1 in the 72 h after ICU admission had significantly higher cumulative fluid balance, lower PaO2/FiO2, and fewer VFD than patients with low levels of Syn-1. Syn-1 levels did not correlate with sequential organ failure assessment score or with APACHE II score.

Conclusions
In our cohort of patients with septic shock, higher circulating level of Syn-1 of cardinal glycocalyx component is associated with more ARDS, cumulative positive fluid balance, and fewer VFD. Measurement of Syn-1 levels in patients with septic shock might be useful for predicting patients at high risk of ARDS.
Tilt and strain change during the explosion at Minami-dake, Sakurajima, on November 13, 2017
Authors: Hotta Kohei , Iguchi Masato 
Published: April 2021

AbstractWe herein propose an alternative model for deformation caused by an eruption at Sakurajima, which has been previously interpreted as being due to a Mogi-type spherical point source beneath Minami-dake. On November 13, 2017, a large explosion with a plume height of 4200 m occurred at Minami-dake. During the 3 min following the onset of the explosion (November 13, 2017, 22:07–22:10 (Japan standard time (UTC + 9); the same hereinafter), phase 1, a large strain with changes up to 120 nstrain was detected at the Arimura observation tunnel (AVOT) located approximately 2.1 km southeast from the Minami-dake crater. After the peak of the explosion (November 13, 2017, 22:10–24:00), phase 2, a large deflation was detected at every monitoring station due to the continuous Strombolian eruption. Subsidence toward Minami-dake was detected at five out of six stations, whereas subsidence toward the north of Sakurajima was detected at the newly installed Komen observation tunnel (KMT), located approximately 4.0 km northeast from the Minami-dake crater. The large strain change at AVOT as well as small tilt changes at all stations and small strain changes at the Harutayama observation tunnel (HVOT) and KMT during phase 1 can be explained by a very shallow deflation source beneath Minami-dake at 0.1 km below sea level (bsl). For phase 2, a deeper deflation source beneath Minami-dake at a depth of 3.3 km bsl was found in addition to the shallow source beneath Minami-dake, which turned inflation after the deflation that occurred during phase 1. However, this model cannot explain the tilt change of KMT. Adding a spherical deflation source beneath Kita-dake at a depth of 3.2 km bsl can explain the tilt and strain change at KMT and the other stations. The Kita-dake source was also found in a previous study of long-term ground deformation. Not only the deeper Minami-dake sourceMD, but also the Kita-dake source deflated due to the Minami-dake explosion.
“Since I’m a little bit more mature”: contraception and the arc of time for women in midlife
Authors: Alspaugh Amy , Reibel Melody D. , Im Eun-Ok , Barroso Julie 
Published: April 2021

Abstract
Background
Contraceptive methods have rapidly evolved over the past several decades, but little research has explored how women interact with contraception over time. Exploring contraceptive beliefs, perceptions, and attitudes of women in midlife can reveal much about how lived experience affects contraceptive decisions and reproductive health choices.

Methods
Individual, semi-structured interviews were conducted with 20 women between the ages of 40 and 55 who had not reached menopause and did not have a permanent method of sterilization. Data were coded using qualitative descriptive methods.

Results
Three major themes were identified: 1) journey toward empowerment; 2) finding the right fit: evolution over time; and 3) anticipating a transition. Past experiences with or fear of side effects and hormones were common reasons to change or avoid certain contraceptive methods. Most participants were happy with their contraceptive method; however, those who were unhappy were more likely to vocalize fatigue at continuing to need contraception as menopause approached.

Conclusion
Approaching contraceptive counseling from a place that considers the journey with contraception over a reproductive life span will help identify how beliefs, perceptions, and attitudes of women affect their contraceptive practices and choices.
Re: Concept and application of relaxing radial retinectomy for retinal detachment with advanced proliferative vitreoretinopathy
Authors: Grabowska Anna , Neffendorf James E. , Williamson Tom H. 
Published: April 2021

AbstractThe following is a response to the recent review article by Girsang and colleagues (Int J Retina Vitreous. 2020;6:46), who describe concept and application of relaxing radial retinectomy for retinal detachment with advanced proliferative vitreoretinopathy. We discuss the distribution of the retinal nerve fiber layer, an aspect not touched on by the authors, and the importance of its consideration in determining visual field outcomes when performing retinectomy. Moreover, we share our clinical experience with both radial and circumferential retinectomy and discuss scenarios where the combination of both is more effective.
Predicting factors of intradialytic hypotension in the last half of hemodialysis therapy
Authors: Aoyama Yumi , Kajimoto Katsuya , Hori Maiko , Otsubo Shigeru , Nitta Kosaku 
Published: April 2021

Abstract
Background
Intradialytic hypotension (IDH) is one of the most frequent complications of hemodialysis. IDH alters a patient’s quality of life and has a strong association with mortality. IDH mainly occurs when ultrafiltration during hemodialysis exceeds the pace of the plasma refill. Ultrasonography has been used to evaluate the intravascular volume status. We evaluated the association between IDH and baseline laboratory data or ultrasound findings during IDH during the latter half of a hemodialysis session.

Methods
Sixty-two patients who underwent hemodialysis were enrolled in this study. The peak early mitral inflow wave velocity (peak E-velocity), the inferior vena cava (IVC) dimensions, and number of B-lines were estimated at two time points (just after the start and at the midpoint of the hemodialysis session). We compared the parameters between the patients without IDH throughout the hemodialysis session (non-IDH group) and patients with IDH only during the latter half of the hemodialysis session (IDH in the latter half group).

Results
Of the 62 study participants, 28 patients were in non-IDH group, and 16 patients were in IDH in the latter half group. The serum sodium level was significantly lower in the IDH in the latter half group (135 ± 4 mEq/L) than in the non-IDH group (138 ± 4 mEq/L) (P = 0.015). The rate of decrease of the peak E-velocity was significantly higher in the IDH in the latter half group (0.33 ± 0.13) than in the non-IDH group (0.24 ± 0.14) (P = 0.037). The best cutoff point of the serum level of sodium was 137 mEq/L, with a sensitivity of 68.8% and specificity of 64.3%. The area under the receiver operating characteristic (ROC) curve was 0.71. The best cutoff point of the rate of decrease of the peak E-velocity was 0.295, with a sensitivity of 73.3% and a specificity of 71.4%. The area under the ROC curve was 0.71.

Conclusions
A low serum level of sodium at baseline and an early decrease in the peak E-velocity during hemodialysis may be related to intradialytic hypotension in the latter half of a hemodialysis session. Careful observation may be needed in the hemodialysis patients in whom the serum level of sodium is below 137 mEq/L or the rate of decrease of the peak E-velocity is over 0.295.
Valorization of pikliz: a spicy meal garnishment in Haitian cuisine
Authors: Louis-Jean James , Sanon Debbie , Louis-Jean Kevin , Sanon Nicole , Stvil Louis-Jean Ruthonce , Thomas Michelle Luvy 
Published: April 2021

AbstractThe biochemical process of fermentation (zymology) is widely practical for foods and beverages. This metabolic process involves microorganisms (bacteria) and their enzymes in the preparation and preservation of foods. Many studies have shown that fermented foods and beverages have various documented health benefits to humans, such as being high in vitamin b, and, among other benefits, having atherogenic and anticarcinogenic properties. This communication discusses the significance of fermentation in Haitian cuisine by focusing onpikliz—a spicy fermented meal garnishment that is widely popular among Haitian dishes. This analysis provides relevant information on Haitian cuisine while examining the underlying mechanisms, compositions, properties, nutritional values, and potential health benefits ofpikliz.This spicy meal garnishment represents the regional, ethnic, and national identity of Haitians living in Haiti and abroad.
Coastal green infrastructure to mitigate coastal squeeze
Authors: Chávez Valeria , Lithgow Debora , Losada Miguel , Silva-Casarin Rodolfo 
Published: April 2021

AbstractInfrastructure is necessary to protect and provide the goods and services required by humans. As coastal green infrastructure (CGI) aims to respect and work with natural processes, it is a feasible response to mitigate or avoid the consequences of coastal squeeze. The concept of CGI is receiving increased attention of late due to the challenges facing us, such as climate change, population growth and the overexploitation of natural resources on the coast. Terms which may be applied to encourage the construction of infrastructure, or to minimize the responsibility for poorly made decisions, often induce misunderstanding. In this paper, the concept of CGI and its use in solving coastal problems is reordered. Four categories are proposed, according to the degree of naturalness of the project: Nature reclamation, Engineered ecosystems, Ecologically enhanced engineering, and De-engineering/Relocation. Existing coastal risk evaluation frameworks can be used to design many types of CGI. Key concepts, challenges and good practices for the holistic management of coastal squeeze are presented from the analysis of successful and unsuccessful CGI projects worldwide.
Evaluating proxies for the drivers of natural gas productivity using machine-learning models
Authors: Kumar Abhash , Harbert William , Hammack Richard , Zorn Erich , Bear Alexander , Carr Timothy 
Published: April 2021

The extensive development of unconventional reservoirs using horizontal drilling and multistage hydraulic fracturing has generated large volumes of reservoir characterization and production data. The analysis of this abundant data using statistical methods and advanced machine-learning (ML) techniques can provide data-driven insights into well performance. Most predictive modeling studies have focused on the impact that different well completion and stimulation strategies have on well production but have not fully exploited the available in situ rock property data to determine its role in reservoir productivity. We have used machine-learning techniques to rank rock mechanical properties, microseismic attributes, and stimulation parameters in the order of their significance for predicting natural gas production from an unconventional reservoir. The data for this study came from a hydraulically fractured well in the Marcellus Shale in Monongalia County, West Virginia. The data classes included measurements aggregated by well completion stage that included (1) gas production, (2) well-log-derived measurements including bulk density, elastic moduli, shear impedance, compressional impedance, brittleness, and gamma measurements, (3) microseismic attributes, (4) long-period long-duration (LPLD) event counts, (5) fracture counts, and (6) stimulation parameters that included the fluid injection volume and average pumping pressure. To identify observable proxies for the drivers of gas production, we evaluated five commonly used ML approaches including multivariate adaptive regression spline, Gaussian mixture model, random forest, gradient boosting, and neural network. We selected five variables including LPLD event count, seismogenic b-value, hydraulic diffusivity, cumulative moment, and fluid volume as the features most likely to impact gas productivity at the stage level in the study area. The data-driven selection of these parameters for their importance in determining gas production can help reservoir engineers design more effective hydraulic-fracture treatments in the Marcellus Shale and other similar unconventional reservoirs. Plain language summary: We use machine-learning methods and data-driven selection of reservoir parameters to rank and better understand their importance in determining gas production, which can help reservoir engineers design more effective hydraulic-fracture treatments in the Marcellus Shale and other similar unconventional reservoirs.
A Remote Surveillance Platform to Monitor General Care Ward Surgical Patients for Acute Physiologic Deterioration
Authors: Safavi Kyan C. , Deng Hao , Driscoll William , Nikolov Milcho , Tolia Kalpan , Wiener-Kronish Jeanine P. 
Published: April 2021

BACKGROUND:
The traditional paradigm of hospital surgical ward care consists of episodic bedside visits by providers with periodic perusals of the patient’s electronic health record (EHR). Vital signs and laboratory results are directly pushed to the EHR but not to providers themselves. Results that require intervention may not be recognized for hours. Remote surveillance programs continuously monitor electronic data and provide automatic alerts that can be routed to multidisciplinary providers. Such programs have not been explored in surgical general care wards.

METHODS:
We performed a quality improvement observational study of otolaryngology and ophthalmology patients on a general care ward from October 2017 to March 2019 during nighttime hours (17:00–07:00). The study was initiated due to the loss of on-site anesthesiology resources that historically helped respond to acute physiologic deterioration events. We implemented a remote surveillance software program to continuously monitor patients for severe vital signs and laboratory abnormalities and automatically alert the ward team and a remote critical care anesthesiology team. The primary end point was the true positive rate, defined as the proportion of alerts that were associated with a downstream action that changed the care of the patient. This was determined using systematic chart review. The secondary end point, as a measure of alarm fatigue, was the average number of alerts per clinician shift.

RESULTS:
The software monitored 3926 hospital visits and analyzed 1,560,999 vitals signs and 16,635 laboratories. It generated 151 alerts, averaging 2.6 alerts per week. Of these, 143 (94.7%) were numerically accurate and 8 (5.3%) were inaccurate. Hypoxemia with oxygen saturation <88% was the most common etiology (92, 63%) followed by tachycardia >130 beats per minute (19, 13.3%). Among the accurate alerts, 133 (88.1%) were true positives with an associated clinical action. Actions included a change in management 113 (67.7%), new diagnostic test 26 (15.6%), change in discharge planning 20 (12.0%), and change in level of care to the intensive care unit (ICU) 8 (4.8%). As a measure of alarm fatigue, there were 0.4 alerts per clinician shift.

CONCLUSIONS:
In a surgical general care ward, a remote surveillance software program that continually and automatically monitors physiologic data streams from the EHR and alerts multidisciplinary providers for severe derangements provided highly actionable alarms at a rate that is unlikely to cause alarm fatigue. Such programs are feasible and could be used to change the paradigm of monitoring.
Surface acoustic microwave photonic filters in standard silicon-on-insulator
Authors: Katzman Moshe , Munk Dvir , Priel Maayan , Grunwald Etai , Hen Mirit , Inbar Naor , Feldberg Moshe , Sharabani Tali , Zektzer Roy , Bashan Gil , Vofsi Menachem , Levy Uriel , Zadok Avi 
Published: April 2021

The processing of analog microwave-frequency signals using optical means becomes increasingly important as part of advanced cellular networks. Chip-level integration of microwave photonic filters, particularly in silicon, is considered necessary for their large-scale deployment. Discrete-time, delay-and-sum filters are widely used to select narrow spectral bands out of broad optical bandwidths. However, the long delays that are required to obtain narrowband filters are difficult to accommodate in integrated optic waveguide paths. In this work, we report discrete-time, integrated microwave photonic filters on standard silicon-on-insulator. Long delays are realized through the conversion of incoming radio-frequency modulation to the form of slow-moving surface acoustic waves. Conversion relies on thermo-elastic expansion of metallic gratings and does not involve piezoelectricity. Information is recovered in the optical domain via photoelastic modulation of probe light in a resonator waveguide. The resonator is patterned to support multiple delayed modulation events. Filters having up to 12 taps are demonstrated, with 175 ns-long delays and passbands as narrow as 5 MHz. The magnitude and radio-frequency phase of each filter tap are designed arbitrarily, independent of those of all others. The coherent summation of delayed waveform replicas is free of environmental phase drifts. Surface acoustic wave modulation of a compact, defect grating waveguide is demonstrated as well. Surface acoustic wave devices can significantly extend the signal-processing capabilities of silicon photonics.
El aporte de la filosofía y la cultura a la vida buena de un cuerpo precario
Authors: Genis Andrea Diáz 
Published: April 2021

Resumen: ¿Se puede llevar un buena vida a partir de una vida mala? A partir de esta pregunta que se hace Butler, tenemos el propósito de reflexionar sobre el caso de César González (ex “pibe chorro” de la villa miseria en Argentina que llega a salir de esa situación y se convierte en escritor y cineasta), a partir del enfoque de capacidades de Martha Nussbaum y la importancia que tiene en la formación humana el cuidado de sí (concepto trabajado por nosotros a partir del último Foucault), la inquietud y el autoconocimiento. Es también una reflexión sobre la importancia de la filosofía ligada al desarrollo humano, al pensamiento crítico y la imaginación creativa y es una reflexión sobre el alcance y la relevancia que tiene la educación y la cultura en la transformación de los sujetos y su vida.
Palabras-clave: Vidas precarias. Enfoque de capacidades. Cuidado de sí. César González.
The contribution of philosophy and culture to the good life of a precarious body
Abstract: Can you left a good life from a bad life? From this question asked by Butler, we have the purpose of reflecting on the case of César Gonzalez ( ex criminal of the misery village in Argentina that comes out of that situation and becomes a writer and filmmaker). Based on Martha Nussbaum's capabilities approach and the importance of caring for oneself in human formation (concept worked by us since the last Foucault), self-care and self-knowledge. It is also a reflection on the importance of philosophy linked to human development, critical thinking and creative imagination and is a reflection on the scope and relevance of education and culture in the transformation of subjects and their lives.
Keywords: Precarious lives. Capability Approach. Self of care. César González.
A contribuição da filosofia e da cultura para a boa vida de um corpo precário
Resumo: Você pode levar uma vida boa no meio de uma vida ruim? A partir desta pergunta feita por Butler, temos o objetivo de refletir sobre o caso de César González (ex-criminoso da vila da miséria na Argentina que sai dessa situação e se torna escritor e cineasta), com base na abordagem As capacidades de Martha Nussbaum e a importância do autocuidado na formação humana (conceito trabalhado por nós desde o último Foucault), inquietação e autoconhecimento. É também uma reflexão sobre a importância da filosofia ligada ao desenvolvimento humano, pensamento crítico e imaginação criativa e uma reflexão sobre o escopo e a relevância da educação e cultura na transformação dos sujeitos e de suas vidas.
Palavras-chave: Vidas precárias. Foco nas capacidades. Autocuidado. César González.
Arte, educación y comunidad en la estética pedagógica
Authors: Massó Castilla Jordi 
Published: April 2021

Arte, educación y comunidad en la estética pedagógica
Resumen: Una de las corrientes estéticas contemporáneas más pujantes, la «estética pedagógica», planteó desde sus comienzos la combinación entre el arte y la educación. Las creaciones respaldadas por esta orientación se basan en muchas de las ideas de las pedagogías críticas de los años 60 e igualmente en los presupuestos de las llamadas últimas vanguardias artísticas. Todas ellas comparten un mismo espíritu emancipador en sintonía con las teorías más críticas con la sociedad de producción capitalista. Pero en los últimos años la «estética pedagógica» se ha visto empujada a problematizar la cuestión de la «comunidad» desde diferentes puntos de vista, partiendo de la base de que no puede haber educación ni arte sin un replanteamiento del espacio en común que ambos ponen en juego.
Palabras clave: Arte. Educación. Política. Comunidad.
Art, Education and Community in Pedagogical Aesthetics
Abstract: one of the most thriving contemporary aesthetic trends, «Pedagogical Aesthetics», raised from its beginnings the combination between art and education. The creations supported by this orientation are based on many of the ideas of the critical pedagogies of the 60s and also on the budgets of the so-called latest artistic avant-gardes. All of them share the same emancipatory spirit in tune with the most critical theories with the capitalist production society. But in recent years the «pedagogical aesthetic» has been pushed to problematize the question of «community» from different points of view, based on the fact that there can be no education or art without a rethinking of the common space that both put into play.
Keywords: Art. Education. Politics. Community
Arte, educação e comunidade em estética pedagógica
Resumo: uma das tendências estéticas contemporâneas mais prósperas, a «estética pedagógica», levantou desde o início a combinação entre arte e educação. As criações apoiadas por essa orientação baseiam-se em muitas das idéias das pedagogias críticas dos anos 60 e também nos orçamentos das chamadas vanguardas artísticas mais recentes. Todos eles compartilham o mesmo espírito emancipatório em sintonia com as teorias mais críticas da sociedade capitalista de produção. Mas, nos últimos anos, a «estética pedagógica» foi levada a problematizar a questão da «comunidade» de diferentes pontos de vista, com base no fato de que não pode haver educação ou arte sem repensar o espaço comum que ambos Eles colocam em jogo.
Palavras-chave: Arte. Educação. Política. Comunidade.
Data de registro:16/06/2020
Data de aceite: 22/07/2020