bluuebunny/crossref_metadata_2025_split huggingface dataset:
Functional tricuspid regurgitation, related right heart remodeling, and available treatment options: good news for patients with heart failure?
Authors: Tadic Marijana , Cuspidi Cesare , Morris Daniel Armando , Rottbauer Wolfang 
Published: July 2021

AbstractSignificant functional tricuspid regurgitation (FTR) represents a poor prognostic factor independent of right ventricular (RV) function. It is usually the consequence of left-sided cardiac diseases that induce RV dilatation and dysfunction, but it can also resulted from right atrial (RA) enlargement and consequent tricuspid annular dilatation. FTR is very frequent among patients with heart failure, particularly in those with reduced LVEF and concomitant functional mitral regurgitation. The development of three-dimensional echocardiography enabled detailed assessment of tricuspid valve anatomy, subvavlular apparatus, and RA and RV changes, as well as accurate evaluation of FTR etiology. Due to high in-hospital mortality risk in patients who were operatively treated for isolated FTR, it has been treated only medically for a long time. Percutaneous approach considers mainly transcatheter tricuspid valve repair (edge-to-edge and annuloplasty) and represents a very attractive option for the high-risk patients. Studies that investigated the effects of different devices showed excellent feasibility and safety, followed by significant reduction in FTR grade, improvement in functional capacity and NYHA class, quality of life, and reduction in hospitalization due to heart failure. Some investigations also reported a decreased mortality in FTR patients. Nevertheless, the results of these investigations should be interpreted with cautious due to the small number of participants and relatively short follow-up. The aim of this review was to summarize the existing data about the clinical importance of FTR and FTR-induced right heart remodeling and currently existing therapeutic approaches for treatment of FTR.
Islam and the COVID-19 Pandemic: Between Religious Practice and Health Protection
Authors: Piwko Aldona Maria 
Published: July 2021

AbstractThis paper concerns a problem, the global pandemic COVID-19, which has influenced religious practices with respect to health protection across the Muslim world. Rapid transmission of the virus between people has become a serious challenge and a threat to the health protection of many countries. The increase in the incidence of COVID-19 in the Muslim community took place during and after the pilgrimages to Iran's Qom and as a result of the Jamaat Tabligh movement meetings. However, restrictions on religious practices have become a platform for political discussions, especially among Muslim clergy. This paper is an analysis of the religious and political situation in Muslim countries, showing the use of Islam to achieve specific goals by the authorities, even at the price of the health and life of citizens.
Re-drawing the Maps for Endemic Mycoses
Authors: Ashraf Nida , Kubat Ryan C. , Poplin Victoria , Adenis Antoine A. , Denning David W. , Wright Laura , McCotter Orion , Schwartz Ilan S. , Jackson Brendan R. , Chiller Tom , Bahr Nathan C. 
Published: July 2021

AbstractEndemic mycoses such as histoplasmosis, coccidioidomycosis, blastomycosis, paracoccidioidomycosis, and talaromycosis are well-known causes of focal and systemic disease within specific geographic areas of known endemicity. However, over the past few decades, there have been increasingly frequent reports of infections due to endemic fungi in areas previously thought to be “non-endemic.” There are numerous potential reasons for this shift such as increased use of immune suppressive medications, improved diagnostic tests, increased disease recognition, and global factors such as migration, increased travel, and climate change. Regardless of the causes, it has become evident that our previous understanding of endemic regions for these fungal diseases needs to evolve. The epidemiology of the newly describedEmergomycesis incomplete; our understanding of it continues to evolve. This review will focus on the evidence underlying the established areas of endemicity for these mycoses as well as new data and reports from medical literature that support the re-thinking these geographic boundaries. Updating the endemic fungi maps would inform clinical practice and global surveillance of these diseases.
Regional Differences in Antifungal Susceptibility of the Prevalent Dermatophyte Trichophyton rubrum
Authors: Jiang Y. , Luo W. , Verweij P. E. , Song Y. , Zhang B. , Shang Z. , Al-Hatmi A. M. S. , Ahmed S. A. , Wan Z. , Li R. , de Hoog G. S. 
Published: July 2021

AbstractIn vitro susceptibility testing forTrichophyton rubrumhas shown resistance to terbinafine, azoles and amorolfine, locally, but epidemiological cutoffs are not available. In order to assess the appropriateness of current first-line antifungal treatment forT. rubrumin China, we characterized antifungal susceptibility patterns of ChineseT. rubrumstrains to nine antifungals and also described the upper limits of wild-type (WT) minimal inhibitory concentrations (MIC) (UL-WT) based on our study and another six studies published during the last decades. Sixty-two clinical isolates originating from seven provinces in China were identified asT. rubrumsensu stricto; all Chinese strains showed low MICs to eight out of nine antifungal drugs. Terbinafine (TBF) showed the lowest MICs of all antifungal classes tested in both the Chinese and global groups, with a 97.5% UL-WT MIC-value of 0.03 mg/L. No non-WT isolates were observed for TBF in China, but were reported in 18.5% of the global group. Our study indicated that TBF was still the most active drug for ChineseT. rubrumisolates, and all strains were within the WT-population. TBF therefore remains recommended for primary therapy to dermatophytosis caused byT. rubrumin China now, but regular surveillance of dermatophytes and antifungal susceptibility is recommended.
Tinea Capitis by Microsporum canis in an Elderly Female with Extensive Dermatophyte Infection
Authors: Yang Zhihui , Chen Wei , Wan Zhe , Song Yinggai , Li Ruoyu 
Published: July 2021

AbstractTinea capitis is a type of dermatophyte infection primarily affecting children. We report a case of an elderly woman with well-controlled diabetes mellitus presenting with a six-month history of erythema with yellow crusts on her scalp and extensive erythematous patches with scales on the body skin. She adopted a stray cat before the disease onset. Dermoscopic findings and manifestation under the Wood’s lamp favoured the diagnosis of tinea capitis. Further microscopic examinations of her scalp, including direct KOH and fluorescence stain examination, fungal culture and polymerase chain reaction sequencing identification confirmed the diagnosis of tinea capitis caused by Microsporum canis. Treatment with oral terbinafine was effective. Adult tinea capitis is often misdiagnosed due to its rarity and atypical presentation. However, in some regions, the incidence of tinea capitis in immunocompetent adults is rising which requires the awareness of clinicians. A thorough history (including the animal contacting history), physical examination and further mycological examinations are required for diagnosis. Trichophyton violaceum is the most common dermatophyte species in most regions while adult tinea capitis caused by Microsporum canis is less common. Terbinafine, griseofulvin and itroconazole have been reported to be effective drugs for the treatment of tinea capitis, and terbinafine can be considered as systemic treatment in elderly patients with comorbidities to reduce the drug–drug interaction.
How Is Fortitude Among Pilgrims on the Camino de Santiago Expressed and Formed? Clues from a Study of Polish Pilgrims
Authors: Seryczyńska Berenika , Duda Tomasz 
Published: July 2021

AbstractIn 2019 alone, the Camino de Santiago (the Way of St. James), one of Europe’s three most significant medieval pilgrimage routes, was followed by 347,511 pilgrims from around the world. This pilgrimage route has been the subject of numerous research projects conducted by international groups of specialists in various scientific disciplines. This study presents correlations between St. Thomas Aquinas’s doctrine on the virtue of fortitude and the experience of Polish pilgrims on the Camino based on 50 in-depth interviews conducted in the summer of 2019 on Monte do Gozo in Santiago de Compostela. This objective was achieved using the methodology of qualitative research following Steinar Kvale’s recommendations. The transcriptions of the interviews were coded based on the classifications in the Summa Theologica by Aquinas, classified into categories, and subsequently analyzed using MAXQDA Analytics Pro 2020. The virtue of fortitude is indispensable in the decision-making process and the ability to put one’s decisions into practice (Morales-Sánchez & Cabello-Medina, 2013. Journal of Business Ethics, 116(4), 717–734). One manifestation of the Camino pilgrims’ virtue of fortitude allowed them to believe that they would be more employable after they returned to their communities.
Convolutors on $${\mathcal S}_{\omega }({\mathbb R}^N)$$
Authors: Albanese Angela A. , Mele Claudio 
Published: July 2021

AbstractIn this paper we continue the study of the spaces $${\mathcal O}_{M,\omega }({\mathbb R}^N)$$

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M
,
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and $${\mathcal O}_{C,\omega }({\mathbb R}^N)$$

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undertaken in Albanese and Mele (J Pseudo-Differ Oper Appl, 2021). We determine new representations of such spaces and we give some structure theorems for their dual spaces. Furthermore, we show that $${\mathcal O}'_{C,\omega }({\mathbb R}^N)$$

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(

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is the space of convolutors of the space $${\mathcal S}_\omega ({\mathbb R}^N)$$

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(

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of the $$\omega $$
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-ultradifferentiable rapidly decreasing functions of Beurling type (in the sense of Braun, Meise and Taylor) and of its dual space $${\mathcal S}'_\omega ({\mathbb R}^N)$$

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(

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. We also establish that the Fourier transform is an isomorphism from $${\mathcal O}'_{C,\omega }({\mathbb R}^N)$$

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onto $${\mathcal O}_{M,\omega }({\mathbb R}^N)$$

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(

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. In particular, we prove that this isomorphism is topological when the former space is endowed with the strong operator lc-topology induced by $${\mathcal L}_b({\mathcal S}_\omega ({\mathbb R}^N))$$

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b

(

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and the last space is endowed with its natural lc-topology.
Co-occurrence network of TV advertisements revealing Japanese lifestyle
Authors: Ito Mariko I. , Ohnishi Takaaki 
Published: July 2021

AbstractThe relationship between culture and the appeals in TV advertisements has been extensively studied. We attempted to reveal the image structure produced by TV commercials in Japan, which may show the cultural features of the country, and to evaluate its temporal change. For this purpose, we constructed and analysed a co-occurrence network of keywords related to TV commercials by using immense data that include the records of all TV commercials aired in the Kanto area in Japan including Tokyo for a period of 15 years. We found a strong heterogeneity of the co-occurrence relationship, where a few keywords, e.g., ‘woman’, ‘man’, ‘animation’, and ‘logo’, co-occur with a huge number of other keywords every year. A community on a co-occurrence network can be regarded as a set of keywords that are mutually associated with each other through TV commercials. We examined the characteristics of the communities by associating them with categories of advertised products and found a temporal change in which the relationship between the communities possessing the image of entertainment and children and the category of PC and A/V gradually increases in strength. However, there was a consistent tendency in the examined period for the product categories related to communities that include ‘man’ to be less associated with those that include ‘woman’ and vice versa, which implicates a gender role inequality underlying the various appeals in TV commercials.
Face-Based Attention Recognition Model for Children with Autism Spectrum Disorder
Authors: Banire Bilikis , Al Thani Dena , Qaraqe Marwa , Mansoor Bilal 
Published: July 2021

AbstractAttention recognition plays a vital role in providing learning support for children with autism spectrum disorders (ASD). The unobtrusiveness of face-tracking techniques makes it possible to build automatic systems to detect and classify attentional behaviors. However, constructing such systems is a challenging task due to the complexity of attentional behavior in ASD. This paper proposes a face-based attention recognition model using two methods. The first is based on geometric feature transformation using a support vector machine (SVM) classifier, and the second is based on the transformation of time-domain spatial features to 2D spatial images using a convolutional neural network (CNN) approach. We conducted an experimental study on different attentional tasks for 46 children (ASD n=20, typically developing children n=26) and explored the limits of the face-based attention recognition model for participant and task differences. Our results show that the geometric feature transformation using an SVM classifier outperforms the CNN approach. Also, attention detection is more generalizable within typically developing children than within ASD groups and within low-attention tasks than within high-attention tasks. This paper highlights the basis for future face-based attentional recognition for real-time learning and clinical attention interventions.
Cannabinoids and their derivatives in struggle against melanoma
Authors: Marzęda Paweł , Drozd Małgorzata , Wróblewska-Łuczka Paula , Łuszczki Jarogniew J. 
Published: July 2021

Abstract
Melanoma is one of the most aggressive malignances in human. Recently developed therapies improved overall survival rate, however, the treatment of melanoma still remains a challenging issue. This review attempts to summarize recent advances in studies on cannabinoids used in the setting of melanoma treatment. Searches were carried out in PubMed, Google Scholar, Scopus, Research Gate. Conclusions after analysis of available data suggest that cannabinoids limit number of metastasis, and reduce growth of melanoma. The findings indicate that cannabinoids induce apoptosis, necrosis, autophagy, cell cycle arrest and exert significant interactions with tumor microenvironment. Cannabinoids should be rather considered as a part of multi-targeted anti-tumor therapy instead of being standalone agent. Moreover, cannabinoids are likely to improve quality of life in patients with cancer, due to different supportive effects, like analgesia and/or anti-emetic effects. In this review, it was pointed out that cannabinoids may be potentially useful in the melanoma therapy. Nevertheless, due to limited amount of data, great variety of cannabinoids available and lack of clinical trials, further studies are required to determine an exact role of cannabinoids in the treatment of melanoma.

Graphic abstract
Sacral Neuromodulation for Lower Urinary Tract Symptoms: Effect of Therapy on Saudi Patient Sexual Function
Authors: Banakhar Mai Ahmed , Youness Ayman 
Published: July 2021

Abstract

Background
Sacral neuromodulation (SNM) is FDA-approved therapy for lower urinary tract and bowel dysfunction. It is newly introduced therapy in Saudi Arabia.

Aim
To evaluate the effect of SNM therapy in both male and female Saudi patient's sexual function.

Methods
A prospective cohort study was conducted for all patients who underwent SNM implantation from January 2016 till January 2020 at a single center in Jeddah, Saudi Arabia. Sexual function was assessed before and after treatment using International Index of Erectile Function (IIEF-5) for men and the Female Sexual Function Index (FSFI) for women.

Main Outcome measures
Sexual function score changes from the baseline was reported. Correlation analysis was studied between IIEF-5 to assess erectile dysfunction and FSFI assessing desire, arousal, orgasm, pain and sexual satisfaction and other collected data including patient's age, functional diagnosis and post void residual (PVR).

Results
The study included 13 total patients (8 female, 5 male) with mean age 47y (33-60). Diagnosis included non-obstructive urine retention (5), refractory overactive bladder (3), combined retention + over active bladder (OAB) (1), pelvic pain syndrome (3) and impotence in 1 patient. All male patients showed significant improvement in their IIEF-5 score from mean pre op 7.8 ±5.7 to post op sore of 19.8±2.3 with significant p value p=0.003.
Female patients showed significant improvement in their FSFI total score from baseline of 18.313±7.4 to post-operative mean FSFI score 26.7±1.8 with p value = 0.013. Domains od FSFI which showed significant improvement were desire, arousal, orgasm and sexual satisfaction with p value =0.002, p=00.1,0.012, and p=0.015. Age, functional diagnosis and PVR did not show significant correlation with IIEF-5 and FSFI score.

Conclusion
Our results suggest that SNM might improve male and female sexual dysfunction regardless of patient's age and diagnosis. Banakhar MA, Younos A. Sacral neuromodulation for lower urinary tract symptoms: effect of therapy on Saudi patient sexual function. Sex Med 2021;9:100388.
Food intake in children and adolescents: a cross-sectional study from 2009/2010 to 2015/2016
Authors: Tell Maria N. , Hedin Katarina , Nilsson Mats , Golsäter Marie , Lingfors Hans 
Published: July 2021

Abstract
The aim was to describe food intake over time in children and adolescents, with respect to age and gender. The present study was a repeated cross-sectional study using self-reported data from a health questionnaire. Data were collected from the School Health Services in south-east Sweden from 44 297 students, 10, 13–14 and 16 years of age, 48 % girls and 52 % boys from 2009/2010 to 2015/2016. Reported intakes for eight foods were analysed in relation to the Nordic Nutrition Recommendations. Seventeen per cent of the students reported an intake in line with the recommendations for at least six of the eight foods fish, vegetables, fruit, mealtime beverages, juice/chocolate drinks, sugar-sweetened beverages, sweets/snacks and pastries. Intake of at least two fruits a day was the recommendation that was followed by the lowest proportion of students (30 %), and this result was stable over the study period. There was a gradual increase over time in the proportion of students who reported an intake in line with the recommendations. Younger students compared to older students, as well as girls compared to boys, reported intakes in line with the recommendations to a statistically significant larger extent. Few students reported intakes in line with the recommendations, although the quality of food intake seems to improve over time. The present results indicate a deterioration in reported food intake in the early years of adolescence. Finding methods to support all children and especially older adolescents to eat healthier, including eating more fruit, is of great importance to public health.
Ultraviolet germicidal irradiation of melted snow and ice samples: inactivation of microorganisms and effects on insoluble microparticles
Authors: Nakazawa Fumio , Goto-Azuma Kumiko 
Published: July 2021

AbstractThe long-term refrigerated storage of melted snow and/or ice samples for analyses of insoluble microparticles (hereafter, microparticles) may be limited by increases in the biological particle concentration caused by microbial growth after ~1–2 weeks. In this study, we examined an ultraviolet (UV) disinfection method for the storage of melted snow and/or ice samples and determined the effects of this method on microparticles. Surface snow obtained from Glacier No. 31 in the Suntar-Khayata Range, eastern Siberia, Russia was divided into two portions for UV treatment and untreated controls. Microparticle concentrations and size distributions (in the range of 0.52–12.0 μm) in the samples were measured using a Coulter counter. Whereas the microparticle concentration in untreated samples increased, no obvious increase was observed over 53 d in the samples subjected to UV treatment. Microbial growth was detected in only untreated samples using a viable particle counter. In addition, the original microparticle concentrations and size distributions were unaffected by UV treatment. Our results demonstrated that the microparticle size distribution in untreated melted water samples reflects the growth, decomposition and succession of microorganisms over time and further indicate that UV irradiation is effective for long-term storage for microparticle analysis.
The semantics of spatial demonstratives in Spanish: a Demonstrative Choice Task study
Authors: TODISCO EMANUELA , ROCCA ROBERTA , WALLENTIN MIKKEL 
Published: July 2021

abstractDemonstratives (this/thatin English) are pivotal in communication. In this study, we show that semantic features of referents systematically influence speakers’ choices of demonstrative forms for Spanish nouns in the absence of a guiding context. We used the Demonstrative Choice Task (DCT), previously applied to two-term demonstrative languages (Danish, English, and Italian), and applied it to Spanish, a three-term demonstrative system (este/ese/aquel), to test if the semantic dimensions driving demonstrative choice overlap with those found for English. 1,639 native Spanish speakers were presented with 480 nouns rated along 76 semantic features and were asked to match each noun with a demonstrative. We found that demonstratives are influenced by the same semantic factors as two-term languages, such as manipulability, valence, and the self. In Spanish, these semantic factors predict the demonstrative choice between the proximaleste/aand a combination of medial and distal formsese/aandaquel/la.Additional semantic factors affect speakers’ preferences forese/aversusaquel/a(e.g., visuality and time). We conclude that many of the semantic attractors influencing the choice of demonstratives are constant across languages, independent of the number of terms characterizing the demonstrative system, and provide a window into the landscape of meaning subserving linguistic reference.
Literacy effects on artificial grammar learning (AGL) with letters and colors: evidence from preschool and primary school children
Authors: SOARES ANA PAULA , SILVA ROSA , FARIA FREDERICA , SANTOS MARIA SILVA , OLIVEIRA HELENA MENDES , JIMÉNEZ LUIS 
Published: July 2021

abstractLiteracy affects many aspects of language and cognition, including the shift from a more holistic mode of processing to a more analytical part-based mode of processing. Here we examined whether this shift impacts the ability of preschool and primary school children to learn the rules underlying a finite-state grammar using an artificial grammar learning (AGL) paradigm implemented with either linguistic (letters) or non-linguistic (colors) materials to further examine if children’s AGL performance was modulated by type of stimuli. Both tasks involved a training phase in which half of the preschool children and half of the primary school children were exposed to a set of either letter or color strings without any information about the rules underlying the construction of those strings. Later, in the test phase, they were asked to decide whether a new set of letter or color strings conformed to those rules to test grammar learning. Results showed that only primary school children showed evidence of learning, and, importantly, only with colors. These findings seem to support the view that learning to read promotes reliance on smaller linguistic units that might hinder the ability of first-graders to learn the rules underlying finite-state grammars implemented with linguistic materials.