bluuebunny/crossref_metadata_2025_split huggingface dataset:
Innovations in Acheulean Biface production at la Noira (France) during Middle Pleistocene in Western Europe
Authors: MEDRANO PAULA GARCIA , Despriée Jackie , Moncel Marie-Hélène 
Published: August 2021

Abstract
The archaeological sequence of la Noira (Centre region, France) yielded two phases of occupation: ca 700 ka (stratum a) and ca 450 ka (stratum c). No site between these two dates has yet been discovered in the area, and this chronological period has thus been interpreted as a gap in settlement from MIS 16 to MIS 12, two crucial phases of occupation in Western Europe, before and after the long glacial event MIS 12 which record the onset of the Acheulean in Europe and earliest evidence of innovations from MIS 12 considered as a shift in human evolution. Here, we compare these two levels and track technological innovations during this time, combining technological analysis with geometric morphometrics with the use of 3D models comparison of the Large Cutting Tools (LCTs). Stratum a yielded an Early Acheulean, one of the few evidence in Europe presents tools with mainly short shaping sequences on local millstone slabs, with special attention to tips, but with clear management of tool volume. Stratum c, dated to the MIS 11, differs in that both local millstone and flints from distant sources show longer shaping sequences, the use of soft hammers for several series of removals on tools, combined with final regularizing retouch on entire edges. The morphometric approach shows a morphological transition from oval to teardrop shapes for the thinnest tools. Our data suggest a clear technological filiation between strata a and c and in la Noira populations from MIS 16 and MIS 12, as suggested for innovations of core technologies and land-use patterns, and raise question on local human behavioral evolution over the Middle Pleistocene in Western Europe.
Citrobacter Keratitis: Predisposing Factors and Clinical Characteristics
Authors: Soleimani Mohammad , Masoumi Ahmad , Tabatabaei Seyed Ali 
Published: August 2021

Abstract
Purpose: To report predisposing factors, clinical presentation, antibiotic sensitivity, and management of Citrobacter-caused infectious keratitis. Methods: We retrospectively reviewed the medical records of culture-proven cases of Citrobacter keratitis in a tertiary referral center for 8 years (from January 2012 to September 2020). Results: Eighteen cases of microbial keratitis due to Citrobacter spp. were identified. The median age of the patients was 66 years (range, 10-89). Thirteen patients were male and 5 were female. Multiple predisposing factors were identified in all eyes, including ocular surface disease (n=8), previous corneal surgery (n=6), and history of ocular trauma (n=6). Five patients were diabetic. Corrected distance visual acuity (CDVA) of patients was light perception (LP) in 8 patients, hand motion (HM) in 7, counting fingers (CF) at 1 meter in 1, and CF at 2 meters in 2 patients. Thirteen eyes exhibited hypopyon in association with corneal infiltration. An area of corneal thinning was observed in 7 eyes (38.9%). Endophthalmitis due to infectious keratitis developed in one patient. In vitro susceptibility testing confirmed reasonable sensitivity to ceftazidime and aminoglycosides. Medical management consisted primarily of topical amikacin (20 mg/ml) combined with topical cefazoline (50 mg/ml) (72.2%). Surgical tectonic procedures were carried out in 7 eyes (38.9%). Conclusion: Citrobacter spp. is a rare cause of bacterial keratitis. It comprises 0.7% of all admitted keratitis cases. Previous keratoplasty and ocular surface problems are important risk factors. The prognosis is not good and surgical tectonic intervention is required in many cases to resolve the corneal infection.
Improved multiobjective differential evolution with spherical pruning algorithm for optimizing 3D printing technology parametrization process
Authors: Cruz Luciano Ferreira , Pinto Flavia Bernardo , Camilotti Lucas , Santanna Angelo Marcio Oliveira , Freire Roberto Zanetti , Coelho Leandro dos Santos 
Published: August 2021

Abstract
Multiobjective optimization approaches have allowed the improvement of technical features in industrial processes, focusing on more accurate approaches for solving complex engineering problems and support decision-making. This paper proposes a hybrid approach to optimize the 3D printing technology parameters, integrating the design of experiments and multiobjective optimization methods, as an alternative to classical parametrization design used in machining processes. Alongside the approach, a multiobjective differential evolution with uniform spherical pruning (usp-MODE) algorithm is proposed to serve as an optimization tool. The parametrization design problem considered in this research has the following three objectives: to minimize both surface roughness and dimensional accuracy while maximizing the mechanical resistance of the prototype. A benchmark with non-dominated sorting genetic algorithm II (NSGA-II) and with the classical sp-MODE is used to evaluate the performance of the proposed algorithm. With the increasing complexity of engineering problems and advances in 3D printing technology, this study demonstrates the applicability of the proposed hybrid approach, finding optimal combinations for the machining process among conflicting objectives regardless of the number of decision variables and goals involved. To measure the performance and to compare the results of metaheuristics used in this study, three Pareto comparison metrics have been utilized to evaluate both the convergence and diversity of the obtained Pareto approximations for each algorithm: hyper-volume (H), g-Indicator (G), and inverted generational distance (IGD). To all of them, ups-MODE outperformed, with significant figures, the results reached by NSGA-II and sp-MODE algorithms.
Hybrid NOMA-Based ACO-FBMC/OQAM for Next-Generation Indoor Optical Wireless Communications Using LiFi Technology
Authors: Hesham Hamis , Ismail Tawfik 
Published: August 2021

Abstract
The light fidelity (LiFi) has been successfully used to achieve high data transfer rates, high security, great availability, and low interference. In this paper, we propose a LiFi system consisting of a combination of non-orthogonal multi-access (NOMA), asymmetrically-clipped optical (ACO) and filter bank multicarrier (FBMC) techniques combined with offset quadrature amplitude modulation (OQAM). The paper also applies a $\mu$-law companding approach for a high peak to average power ratio (PAPR) reduction of the FBMC/OQAM scheme. The combination of NOMA, ACO-FBMC/OQAM, and $\mu$-law companding allows a significant increase in throughput and a significant reduction in non-served users. An appropriate algorithm is developed considering two scenarios, maximize the throughput and minimize the number of blocked (non-served) users. The results show that the throughput of the system can be increased by $1.8$ compared to FBMC and OFDM. Furthermore, the proposed system reduces the number of blocked users below $10\%$, while the system can provide $30\%$ or $60\%$ in case only the FBMC or OFDM is used, respectively.
Association between depressive symptoms and medical care utilization in South Korean older adults with chronic diseases: A cross-sectional study
Authors: Park Yoon Sik , Park Eun-Cheol 
Published: August 2021

Abstract
BackgroundThis study examined the effects of depressive symptoms on medical care utilization among South Korean older adults with chronic diseases.MethodsA national sample of 3,921 elders with chronic diseases participated in the Korean Longitudinal Study of Aging. Using multiple logistic regression, odds ratios (ORs) were calculated for the effects of depressive symptoms on medical care utilization.ResultsOlder adults with depressive symptoms had fewer outpatient visits (OR = 0.81, 95% confidence interval [CI] = 0.67–0.98) and more inpatient hospitalizations (OR = 1.49, 95% CI = 1.13–1.97) than those who did not suffer depressive symptoms. Participants with depressive symptoms visited outpatient clinics less often (OR = 0.69, 95% CI = 0.48–0.97) and were hospitalized more frequently (OR = 1.81, 95% CI = 1.04–3.16) than were men without depressive symptoms. Patients with depressive symptoms with hypertension and diabetes were hospitalized more often (OR = 2.77, 95% CI = 1.45–5.30).ConclusionsDepressive symptoms and chronic diseases are common among elders in South Korea, often resulting in decreased outpatient visits and increased inpatient hospitalization. These findings suggest the necessity for management of chronic disease in elders with depressive symptoms.
Determination of elastic constants of functionalized graphene-based epoxy nanocomposites: A molecular modeling and MD simulation study
Authors: Yadav Aman , Kumar Amit , Sharma Kamal 
Published: August 2021

Abstract
The effect of carboxyl (–COOH) functionalized graphene (FG) on the mechanical properties of its epoxy-based nanocomposites has been investigated by Molecular Dynamics (MD) simulations. Simulations cells of nanocomposites with varying wt% of FG (1, 2 & 3 wt%) were constructed using Material Studio 6.0. Obtained MD simulation results show improved mechanical properties such as elastic modulus, bulk modulus, shear modulus, and the Poisson ratio of the FG/epoxy nanocomposites than that of pure epoxy. Moreover, the computational results of nanocomposites have also been validated well with existing experimental data. Therefore, the current MD simulation shows a decent computational sign for the existing experimental and simulation outcomes on mechanical properties of FG/epoxy nanocomposites.
Evaluation of Health-related Quality of Life in Iranian General Population during the COVID-19 Pandemic. A cross sectional study
Authors: Shiri Maryam Shirvani ,   Hassan Karami2, Sari Ali Akbari , Tatari Maryam , Emamgholipour Sara , Afshari Somayeh 
Published: August 2021

Abstract

Purpose One of the most important questions is how the COVID-19 epidemic affects health-related quality of life (HRQOL) in the general population. This study aims to know about the impact of the COVID-19 epidemic on the HRQOL in the general population in Iran.MethodsAn online survey was developed and participants were recruited via social media (What’s up, Telegram) from Fars province residences from 3th to the 20th of November 2020. Data of this cross-sectional study were collected by a researcher-made demographic, EuroQol-5 Dimension (EQ-5D), and Visual Analog Scale (VAS) questionnaires. The multivariate logistic regression model and CLAD Regression was used for the five health dimensions, and the factors associated with the EQ-5D Index were investigated. Results The mean EQ-5D Index and EQ-VAS of the respondents were 0.80 and 77.53, respectively. The most frequently reported problems were pain/discomfort (P/D) (44.17%) and anxiety/depression (A/D) (53.69%). Logistic regression models showed that the risk of P/D among old people, who were worried about getting COVID-19, and the risk of A/D among people with male, having hypertension and asthma diseases, unemployment, having insurance, and worry about getting COVID-19 were significantly high. The results of CLAD regression indicated that low income (very low and low income), having hypertension, and having asthma were inversely associated with the EQ-5D Index score. Data collection through an online questionnaire could be prone to selection bias. ConclusionAccording to the results, the mental health of people, especially those with chronic diseases and low-income must be considered during epidemics or other emergencies.
Cancer and industrial activities in China
Authors: Zhang Xuemei , Yin Haitao , Shimshack Jay 
Published: August 2021

Abstract
Associations between pollution and life expectancy, infant mortality, and cardiorespiratory disease are documented in China. Yet, less is known about environmental drivers of Chinese cancers. Here, we systematically link polluting industrial activity to cancer incidence, cancer mortality, and cancer cluster designations. We investigate county-level associations between industrial production and age-adjusted incidence and mortality reported in official cancer registries. We then combine the locations of roughly 3 million enterprises with administrative data from roughly 600,000 villages and cancer cluster documentation from 380 villages. We show that county-level value-added from industry is associated with age-adjusted incidence and mortality for all cancers; bronchus, trachea, and lung cancers; stomach cancers; and esophageal cancers. We show that the odds that a village contains a documented cancer cluster increase 3-4 times if the village contains a pollution-intensive industrial facility. Leather, chemical, and dye enterprises appear to drive results. All else equal, smaller facilities increase the odds of cancer clusters.
Biochemical Markers of Environmental Stress Tolerance in Finger Millet [Eleusine coracana (L) Gaertn] Germplasm of Central Himalayan Region
Authors: Trivedi Ajaya Kumar , Verma S. K. , Tyagi R. K. , Hemanataranjan A. 
Published: August 2021

Abstract
Round the globe, availability of the germplasm of suitable crops for cultivation in remote, inaccessible and resource poor terrains is crucial for food security in these regions. Rich diversity of millets, which are highly tolerant to extreme weather conditions, is available in the Central Himalayan Region (CHR). However, biochemical evaluation of available germplasm for food security is a major issue yet to be addressed properly. In this backdrop plant exploration and germplasm collection expeditions were conducted to collect and evaluate the genetic diversity of finger millet (Fig. 1). A total of 314 accessions having traits of agronomic importance were collected and evaluated for three consecutive years. In addition to battery of biochemical traits, yield was recorded to find out suitable germplasm for large scale cultivation/ breeding programme. At flowering stage variability in antioxidants level of leaves such as glutathione and ascorbate ranged from 105.27 – 423.63 mmol.g-1FW and 4.89 – 10.21 mmol.g-1FW respectively. Extensive variability in the activity of enzymes important for multiple abiotic stress tolerance viz., catalase (115 – 855 mmol hydrogen peroxide decomposed.min-1.mg-1 protein), peroxidase (1.24 - 6.35 mmol substrate.min.-1.mg-1 protein), superoxide dismutase (1236 – 2963 enzyme U.mg-1 protein), glutathione reductase (0.53 – 2.14 mmol substrate.min-1.mg-1 protein), ascorbate peroxidase (1.86 – 7.04 mmol substrate.min-1.mg-1 protein), monodehydroascorbate reducatase (1.11 – 4.41 mmol substrate.min-1.mg-1 protein), dehydroascorbate reducatase (0.34 – 1.36 mmol substrate.min-1.mg-1 protein) was also recorded. Worldwide Abiotic/ environmental stresses hamper agricultural production. Enzymatic and non-enzymatic defence system precisely controls this situation. Hence, biochemical evaluation might be an appropriate strategy for identification of suitable germplam to combat the problem of food security in such areas.
Design And Optimization of Integrated Mach_ Zehnder Modulators In X-Cut Lithium Niobate Thin Film
Authors: Mohammed Luma Z. , Fakhri Makram A , Abass A. K. , Salim Evan T. , Hashim U. 
Published: August 2021

Abstract
The Mach-Zehnder electro-optic modulator (MZM) was designed and fabricated using the AFM COMSOL program and the pulse laser deposition (PLD) technique. The PLD technique was used to deposit silicon, silicon oxide and LN thin film. Previously estimated optical properties of the prepared films were employed in the theoretical design of the modulator. Optimum device parameters were obtained, which delivered a considerable figure of merit (Vπ.L) values within the range of 2.12 to 2.25 at a device length of 2 cm.
Phase shifter based on an ultrathin superconducting bilayer with a through-hole for a superconducting device
Authors: Ishizu Hiroshi , Yamamori Hirotake , Arisawa Shunichi , Tokiwa Kazuyasu , Tanaka Yasumoto 
Published: August 2021

Abstract
Applying a radian phase shift other than 2π is a key issue for superconducting circuits, such as flux qubits. The magnetic flux is useful when generating a phase shift. However, a quantized magnetic flux accompanying a trapped vortex in a superconductor does not have a phase shifter function. The magnetic flux generated by an external field generates noise. In this study, we propose a phase bias system that does not require an external field during operation. We confirm the phase shift of a direct current superconducting interference device (SQUID) placed on an ultrathin superconducting Nb bilayer with a through-hole by cooling it to a temperature below the superconducting transition temperature with an external field. Although the cause of the phase shift in our system is unclear, we believe that it may be caused by a fractional quantum in the bilayer. When the SQUID is replaced by a qubit, the phase shift can be applied to a phase bias.
Design, Simulation and Fabrication of a New Terahertz Cross-shaped Metamaterial Bandpass Filter to Obtain a Narrow Frequency Bandwidth
Authors: shahounvand hojatollah , Fard Azim , Tavakoli Mohammad Bagher 
Published: August 2021

Abstract
In this study, a new terahertz cross-shaped metamaterial bandpass filter is designed, simulated and fabricated. It provides a very good transmission coefficient and much lower unwanted frequencies than other filters do. The simulation is conducted by the CST STUDIO software and the FDTD method.
Gradients of a Sandwich-structured Immunosensor Controlled Using Magnetized Masks for Determination of Human Serum Albumin Using Electrochemiluminescence
Authors: Huang Chun-Yao , Chang Chi-Jung , Huang Bohr-Ran , Lu Chien-Hsing , chen jemkun 
Published: August 2021

Abstract
The authors have requested that this preprint be removed from Research Square.
Anthocyanin: A Natural Dye Extracted From Hibiscus Sabdariffa (L.) For Textile and Dye Industries
Authors: Sankaralingam Bharath , Balan Leeba , Chandrasekaran Sriram , A Muthu Selvam 
Published: August 2021

Abstract
Environmental pollution is one of the major issues faced by all the countries throughout the world. To prevent the environment scarcity and crisis faced in day-to-day life due the increasing chemical industries, usage of chemicals and the effluents processed out after the treatment also consists of some trace elements in them. Hence the extraction of enzymes on natural basis forms an alternative criteria for the production of dye in order to reduce pollution which in turn helps to nourish and protect the environment for future generations. Hibiscus sabdariffa (L) has a rich source of anthocyanins which is further enhanced by callus production and synthesized by increasing the sucrose concentration. Anthocyanin pigments were extracted using acidified ethanol and the dye obtained was screened for GL-MS analysis and its dyeing process in textile industry. The study showed significance properties along with coloring nature on the clothes used. Color of anthocyanin pigment depends on pH maintained and also shows the adaptability towards the nature with varied environmental conditions
Gender-Related Differences In Treatment Patterns And Outcomes of Patients With Atrial Fibrillation: Insights From The MISOAC-AF Trial
Authors: Vouloagkas Ioannis , Kartas Anastasios , Samaras Athanasios , Papazoglou Andreas S. , Moysidis Dimitrios V. , Vrana Eleni , Papanastasiou Anastasios , Baroutidou Amalia , Botis Michail , Kotzampasis Georgios , Liampas Evangelos , Zegkos Thomas , Mouratoglou Sophia Anastasia , Karvounis Haralambos , Tzikas Apostolos , Giannakoulas George 
Published: August 2021

Abstract
PurposeTo assess the gender-related differences in the treatment patterns of patients with atrial fibrillation (AF), and their prognostic value.MethodsIn this post-hoc analysis of a randomized controlled trial, 1140 hospitalized patients with comorbid AF were followed-up for a median of 2.6 years. Kaplan-Meier and multivariable Cox-regression analyses assessed the adjusted hazard ratios (aHRs) for outcomes in males and females, according to oral anticoagulation (OAC) type (vitamin K antagonist or non-vitamin K antagonist oral anticoagulants), rhythm or rate control treatment. The primary outcome was all-cause mortality and the secondary outcomes were stroke and the composite of any hospitalization or cardiovascular death. ResultsAmong 622 males and 518 females, use of OAC (61% vs 62%), rate control (56% vs 57%), and rhythm control (31% vs 28%) treatments was similar (all p>0.05). In males, use of rate control, as compared with rhythm control, was independently associated with higher rates of all-cause mortality (aHR=2.06; 95% confidence interval [CI] 1.24-3.41) and the composite of hospitalization or cardiovascular death (aHR=1.34, 95% CI 1.01-1.85). In females, use of rhythm control was significantly associated with higher rates of hospitalization-or cardiovascular mortality (aHR=1.74, 95% CI 1.03-2.94). Among genders, stroke rates were similar regardless of OAC type, rate or rhythm control treatment.ConclusionsIn patients discharged from the hospital with comorbid AF, the use of OAC, rhythm or rate control treatment was similar among genders. However, males seemed to benefit more from rhythm, whereas females from rate control treatment.
Application of Bispectrum Diagonal Slice Feature Analysis in Tool Wear States Monitoring
Authors: Yang Bin , Wang Min , Zan Tao , Gao Xiangsheng , Gao Peng 
Published: August 2021

Abstract
Tool wear is unavoidable during machining, which is one of the most common tool failure modes. It is significant to evaluate the tool state quickly and effectively for timely tool change strategy. The cutting vibration signals after tool wear show strong non-Gaussian characteristics. Higher order spectrum is a powerful tool for analyzing the non-Gaussian characteristics of signals, and can restrain noise and provide more information than classical power spectrum analysis. This paper presents a milling tool wear state monitoring method based on higher order spectrum entropy. Due to the large amount of calculation of bispectrum, bispectrum diagonal slice is investigated. And the diagonal slice spectral entropy is proposed as tool wear indicator to monitor tool state. To verify the proposed method, cutting vibration signal of CNC machining center were collected and analyzed. The experimental results showed that the proposed approach can effectively monitor and diagnose the tool state, and has good robustness. It is feasible and effective for on-line monitoring milling tool wear.
A Novel Fluorescence “Turn-Off” Sensor Base On A Triazole-Linked BINOL-Glucose Derivative For The Sensitive Detection of Copper Ion
Authors: Wang Huizhen , Liu Yang , Sun Xiaoxia , Hu Yu 
Published: August 2021

Abstract
A novel sensitive chiral fluorescent “turn-off” sensor based on 3,3′-positions modified triazole-linked BINOL-Glucose derivative has been synthesized via “click” reaction. The fluorescence emission intensity of (S, β-D)-1 was almost completely quenched along with obvious color change from yellow to green upon the coordination with a Cu(II) ion while other metal ions had no obvious change. The detection limit of the sensor (S, β-D)-1 toward copper ion was calculated to be 0.31 μmol L-1. The stoichiometry ratio of (S, β-D)-1-Cu2+ complex was proved to be 1:1 by the analysis of NMR spectroscopic, ESI-MS data and the job’s plot. HNMR spectroscopic and IR were also used to study the mechanism, demonstrated copper ion was coordinated with (S, β-D)-1 by 1+1complex formation.