bluuebunny/crossref_metadata_2025_split huggingface dataset:
The oral cavity micro-biocenosis in case of desquamative glossitis associated with small intestinal bacterial overgrowth
Authors: Uspenskaya О. А. , Schevchenko Е. А. , Kazarina N. V. , Legostaeva M. V. 
Published: July 2021

Relevance of the research topic.Small intestine bacterial overgrowth (SIBO) is one of the major factors in the development and persistence of digestive diseases and associated non-digestive disorders. The human gastrointestinal tract microbiota of different biotypes features a community of microorganisms with complex interrelationships. The mouth is the beginning of the digestive system and most easily accessible organ for specimen collection. Assessment of the oral mucosal surface works as a diagnostic test reﬂecting a somatic pathogenesis at its earliest stages. A hydrogen breath test is a non-invasive diagnostic tool for SIBO. The test entails measuring the hydrogen concentration in the exhaled air which is the metabolite of a quantitatively and qualitatively changed intestinal microﬂora. Small intestinal microbiota imbalance triggers the impairment of other gastrointestinal tract organs. It can cause oral, upper respiratory and gut tract microbial dysbiosis.Purpose.The main concern of this study is to explore the oral microbiota of patients with desquamative glossitis coupled with SIBO.Methods and materials.Clinical studies of 36 patients with desquamative glossitis and varying degrees of severity of SIBO generated data for this research. The comparison group comprised 12 persons with desquamative glossitis not paired by SIBO. The generated data was juxtaposed to normal reference values of the oral microbiota biocenosis. SIBO was diagnosed through hydrogen breath monitoring provided by the Gastro+Gastroliyser (BEDFONT) system while oral microﬂora was assessed based on culture tests.Results.The research showed that patients with more severe SIBO and desquamative glossitis manifest a more apparent oral dysbiosis with a simultaneous decrease of normal bacteria and an increase in the amount of conditionally pathogenic bacteria. However, patients who have desquamative glossitis but do not suffer from SIBO tend to show a stable normal microbial ﬂora and a growth of conditionally pathogenic bacteria.Summary.The research revealed that the deranged oral microbiota of patients with desquamative glossitis vary in its degree depending on the severity of SIBO as shown by hydrogen breath tests.
Features of morphological changes of peridont tissues in patients with β-thalassemia major
Authors: Shadlinskaya R. V. , Qasimov E. K. , Rzayev F. Q. 
Published: July 2021

Relevance of the research topic.Β-thalassemia major is a hereditary blood disease, the functional manifestation of which is the defciency of synthesis of the β hemoglobin chain, leading to the occurrence of severe hypochromic anemia in the frst two years of postnatal development. Treatment of the disease requires a lifelong transfusion, which leads to the iron overload disorder. The development of hemosiderosis contributes to the chronization of inﬂammatory processes and cellular modifcation of organs and tissues, including the oral cavity. Inevitable metabolic disorders that occur during β-thalassemia prevents the full functional participation of macro- and microelements in metabolic processes in the periodontium, which is necessary for collagen modifcation.Purpose.The aim of the study is to identify the features of morphological changes in the gingival mucous membrane in patients with β-thalassemia major with generalized gingivitis in remission stage in order to determine potential points of application of additional corrective therapy. Materials and methods. The study included 12 patients with β-thalassemia major (the average age of the subjects was 15 ± 0.1 years). Dental examination was carried out in accordance with the recommendations of the WHO, 1990. Araldite-Epon blocks were formed according to the generally accepted method. The production of semi- (1-2 microns) and ultrathin (35-70 nm) sections were obtained using a Leica EM UC7 ultramicrotome (Germany). Semi-thin sections (1-2 μm) were stained by trichrome staining according to F. D'Amico (2005). Viewing of stained and unstainted ultrathin sections was performed on an JEM-1400 electron microscope (Japan) at an accelerating voltage of 80-120 kV.Results.Periodontal modifcation in the remission stage of catarrhal-sclerosing gingivitis in patients with β – thalassemia major is morphologically marked by disorganization of the connective tissue with destruction of the collagen structures and defciency of the presence of immunocompetent cells in its matrix. Elements of dense connective tissue spread from the papillary part of the lamina propria, where elements of loose connective tissue are usually located. The accumulation of immunocompetent cells in the composition of the connective tissue and in the vascular elements's lumen (both blood and lymphatic) of the lamina propria is not detected.Summary.An inﬂammatory periodontal disease in patients with β-thalassemia major is characterized by marked disorganization of the connective tissue, which requires therapy aimed to develop a correction of mineral metabolism, antioxidant protection and activate the mechanisms of anti-infective protection of the periodontal tissues.
AN APPROACH TO ASSESSING THE PARAMETERS OF THE REGIONAL ATTRACTIVENESS OF THE REGION'S ECONOMY FOR INTERNATIONAL LABOR MIGRANTS
Authors: Гризовская Дарья Викторовна 
Published: July 2021

Для современного этапа экономического развития характерно наличие в региональной экономике изменения соотношения числа международных трудовых мигрантов и числа эмигрантов, что выражается, с одной стороны, в потере значительной части трудоспособного и высококвалифицированного населения, а с другой, - в увеличении доли низкоквалифицированного труда из-за международной трудовой миграции. Целью исследования является разработка регрессионной модели оценивания миграционной привлекательности региона по многомерным данным, представляющим макроэкономические показатели. Методологической основой исследования является комплексный подход, в рамках которого понятие «миграция» рассматривается в качестве объективного фактора, обеспечивающего развитие экономики региона и представляющего собой целеориентированный процесс, заключающийся во въезде в страну международных трудовых мигрантов. Это, с одной стороны, предоставляет возможности развития региональной экономики, а с другой, - усиливает риски экономического развития региона. Научная новизна исследования представлена разработкой подхода к оценке количественных и качественных параметров привлекательности экономики региона для международных трудовых мигрантов с учетом приоритетов и направлений развития региональной экономики.
The current stage of economic development is characterized by the presence in the regional economy of a change in the ratio of the number of international labor migrants to the number of emigrants, which is expressed, on the one hand, in the loss of a significant part of the able-bodied and highly skilled population, and on the other, in the increase in the share of low-skilled labor due to international labor migration. The aim of the study is to develop a regression model for assessing the migration attractiveness of the region from multivariate data representing macroeconomic indicators. The methodological basis of the study is an integrated approach, in which the concept of "migration" is considered as an objective factor that ensures the development of the region's economy and is a targeted process consisting in the entry of international labor migrants into the country. This, on the one hand, provides opportunities for the development of the regional economy, and on the other, increases the risks of the economic development of the region. The scientific novelty of the study is represented by the development of an approach to assessing the quantitative and qualitative parameters of the attractiveness of the region's economy for international labor migrants, taking into account the priorities and directions of the development of the regional economy.
DEVELOPMENT OF ECONOMIC FUNCTIONS OF THE STATE IN THE CONTEXT OF DIGITALIZATION
Authors: Руденко Ирина Владимировна 
Published: July 2021

Цель статьи: обоснование необходимости корректировки функций государства и механизма их осуществления в зависимости от функционирования хозяйственной системы в условиях цифровой трансформации. Научная новизна: реализация экономических функций государства с помощью цифровых технологий рассматривается на основе холистического подхода через взаимодействие частных и общественных интересов в процессе совместного принятия решений. По результатам проведенного исследования сделан вывод о том, что использование современных инструментов реализации государственного администрирования, таких как, цифровые платформы, краудсорсинг, приводит к взаимодействию интересов всех субъектов современного общества, что способствует качественным изменениям в развитии экономических функций государства в условиях цифровизации.
The purpose of the article is to justify the need to adjust the functions of the state and the mechanism for their implementation depending on the functioning of the economic system in the context of digital transformation. Scientific novelty: the realization of the economic functions of the state through digital technologies is considered on the basis of a holistic approach through the interaction of private and public interests in the process of joint decision-making. According to the results of the study, it was concluded that the use of modern tools for the implementation of public administration, such as digital platforms, crowdsourcing, leads to the interaction of the interests of all subjects of modern society, which contributes to qualitative changes in the development of the economic functions of the state in the conditions of digitalization.
THE PROSPECTS OF SMALL BUSINESS DEVELOPMENT IN THE RUSSIAN ECONOMY
Authors: Албендов Рашад Мугабил оглы 
Published: July 2021

Цель статьи - рассмотреть динамику развития малого бизнеса в экономике России и наметить вектор его дальнейшего движения. Важность малого бизнеса признана во всем мире, малые предприятия создают рабочие места и обеспечивают существенную долю населения доходами, что позволяет говорить об актуальности рассматриваемой темы. В статье рассматриваются проблемы и сложности развития и расширения малого бизнеса. Элемент научной новизны заключается в выявлении некоторых проблем малого бизнеса на современном этапе.
The purpose of the article is to consider the dynamics of small business development in the Russian economy and outline the vector of its further movement. The importance of small businesses is recognized throughout the world, small enterprises create jobs and provide a significant share of the population with incomes, which allows us to talk about the relevance of the topic. The article discusses the problems and complexities of small business development and expansion. An element of scientific novelty is the identification of some problems of small businesses at the present stage.
COMMERCIALIZATION OF NEW KNOWLEDGE AND THE CONCEPT OF «ACADEMIC CAPITALISM»
Authors: Дадаев Якуб Элхазурович , Закриева Зинаида Магомедовна 
Published: July 2021

Статья посвящена рассмотрению особенностей появления и распространения в мире феноменов «академический капитализм», «университетское предпринимательство», нового типа организации деятельности университетов, ориентированных на предпринимательство в сфере образования. Целью статьи является исследование теоретико-методологических основ инновационного развития системы образования на базе анализа феномена университетского (академического) предпринимательства, оценки его роли в инновационном развитии общества и на основе изучения исторических причинно-следственных связей - рассмотрение причин возникновения «академического капитализма» и развития университетского предпринимательства. В статье определено, что «академический капитализм» является интеллектуально-знаниевой предпринимательской составляющей капиталистической экономической системы, которая непосредственно влияет на его подсистемы - производительные силы, технико-экономические и производственные отношения, хозяйственный механизм. Научная новизна полученных результатов заключается в обосновании такого феномена как «академический капитализм», позволяющего эффективное использование его технологии и получение выгоды от академического (университетского) предпринимательства образовательным организациям России для достижения научно-технических, технологических и финансовых успехов.
The article is devoted to the consideration of the peculiarities of the emergence and spread of the phenomena of «academic capitalism», «university entrepreneurship» in the world, a new type of organization of the activities of universities focused on entrepreneurship in the field of education. The purpose of the article is to study the theoretical and methodological foundations of the innovative development of the education system based on the analysis of the phenomenon of university (academic) entrepreneurship, assessment of its role in the innovative development of society and based on the study of historical causal relationships - consideration of the causes of the emergence of «academic capitalism» and the development of university entrepreneurship ... It is determined that «academic capitalism» is the intellectual and knowledge entrepreneurial component of the capitalist economic system, which directly affects its subsystems - productive forces, technical, economic and production relations, economic mechanism. The scientific novelty of the results obtained lies in the justification of such a phenomenon as «academic capitalism», which allows the effective use of its technology and benefits from academic (university) entrepreneurship to educational organizations in Russia to achieve scientific, technical, technological and financial success.
Does Convergence Liberalism Risk Anarchy?
Authors: Schultz-Bergin Marcus 
Published: July 2021

Public reason liberals argue that coercive social arrangements must be publicly justified in order to be legitimate. According to one model of public reason liberalism, known as convergence liberalism, this means that every moderately idealized member of the public must have sufficient reason, of her own, to accept the arrangement. A corollary of this Principle of Public Justification is that a coercive social arrangement fails to be legitimate so long as even one member of the public fails to have sufficient reason to endorse the arrangement. This high bar for justification has led many critics, most notably David Enoch, to argue that convergence models are incapable of vindicating liberalism. They argue that in a sufficiently diverse society, there will always be someone for whom an arrangement is not justified, and therefore convergence liberalism leads to anarchy – the view that no law or coercive social arrangement is legitimate. Other critics accept that convergence liberalism could vindicate core liberal institutions but nothing more, and thus argue that the view makes libertarians effective “dictators”. In either case, critics hold that this objection is sufficient to reject convergence liberalism, either in favor of alternative public reason views or as a means of rejecting all public reason views.
In this paper I argue that convergence liberalism can overcome this anarchy objection. I show that the objection largely rests on misinterpretations of convergence liberalism, and thus clarify aspects of the theory. However, I also show that internal debate over the scope of public justification – what stands in need of justification – must be resolved in favor of a wide scope, encompassing both State-based and non-State-based coercion, in order to overcome the anarchy objection. Therefore, my response to the anarchy objection has implications for how convergence liberalism should be developed going forward.
Dampak Perubahan Sistem Otomasi Slims Ke Inlislite Di Perpustakaan SMK Negeri 9 Bandung
Authors: Indah Rosiana Nurwa , Syam Rifqy Zaenai Achmad , Aulia Uul 
Published: July 2021

ABSTRACTThis research was conducted to determine the impact of changes to the Slims to Inlislite system at the SMK Negeri 9 Bandung Library. The research method that researchers use is descriptive qualitative. Data collection techniques used by researchers for research are observation and interviews. Descriptive data analysis method, with data analysis technique in the form of data reduction. Presentation of data, drawing conclusions, and verification. . The results of research that have been researchers show that the impact of the Change in the Slims to Inlite Automation System at the SMKN 9 Bandung Library, has an impact on convenience for librarians. In Inlislite there is also a feature that provides information regarding borrowing data, such as sanctions or fines and delays in returning books which are only confirmed by scanning a barcode. So that it can overcome the queues of visitors and can also save time and effort for librarians in their work.Key words: Automation impact; Slims; integrated library system (Inlislite); School library ABSTRAK Penelitian ini dilakukan bertujuan untuk mengetahui dampak dari perubahan sistem Slims ke Inlislite di Perpustakaan SMK Negeri 9 Bandung. Metode penelitian yang peneliti gunakan adalah kualitatif deskriptif. Teknik pengumpulan data yang digunakan peneliti untuk penelitian yaitu observasi dan wawancara. Metode analisis data deskriptif, dengan teknik analisis data berupa reduksi data. Penyajian data, penarikan kesimpulan, dan verifikasi. . Hasil penelitian yang telah peneliti menunjukan bahwa dampak Perubahan Sistem Otomasi Slims Ke Inlislite Di Perpustakaan Smkn 9 Bandung, memberi dampak kemudahan bagi pustakawan. Di Inlislite juga terdapat fitur yang memberikan informasi data peminjaman mengenai seperti misalnya sanksi atau denda dan keterlambatan waktu pengembalian buku yang hanya dikakukan dengan scan barcode. Sehingga dapat mengatasi antrean pemustaka dan juga dapat menghemat waktu dan tenaga pustakawan dalam pekrjaannya.Kata kunci: dampak otomasi; slims; integrated library system (inlislite); perpustakaan sekolah
The influence of feed additives used to correct metabolic processes in the rumen cows to biochemical indicators of blood from after calving
Authors: Khomenko R. , Semenov B. , Kuznetsova T. 
Published: July 2021

Purpose: estimation of the possibility of using a mixture of feed additive "BioGrom SC" and the food antibiotic "Monenzin" for normalizing metabolic processes in highly productive cows in the transit period.Materials and methods. Studies were conducted because of the tribal plant of the Leningrad region. Two groups of animals were selected on the principle of analogs (experimental and control) 20 goals in each. The experimental group of cows 21 days before the calving and for 14 days after the calves were given a mixture of feed additive "BioGrom SC" and the food antibiotic "Monenzin". For the cottage additives, calcium carbonate (chalk) was used as a filler in the amount of 250 g with the addition of 10-15 g. Supplements "BioGrom SC" by 1 head. The mixture was prepared at the rate of 20 goals and a food antibiotic "Monenzin" was added to it at the rate of 100 mg per 1 kg of a mixture of feed additive with filler. The resulting mixture was fed by animals of the experimental group. All animal experimental and control groups take blood for 21 days before the hotel. The total protein, beta hydroxy acid, acetoacetic acid, alkaline blood reserve, calcium-phosphoric ratio, glucose is determined. At the end of the transit period on the 21st day of lactation, the blood of animal control and experimental groups was repeatedly investigated.Results. In the cows of the experimental group, in comparison with the cows of the control group at the end of the transit period, a decrease in such biochemical indicators was observed as beta hydroxy acid (a decrease to 0.84 ± 0.03 mmol / l), acetoacetic acid (decrease to 0.4 ± 0, 04 mmol / l). The animals of the experimental group decreased the content of the general protein (77.0 ± 0.08 g / l). Also, the data of the backup alkalinity of blood (acidose indicator) are within reference values. Calcium phosphorus ratio was also within the normal range.Conclusion. Introduction to the diet of a mixture of feed additive "BioGrom SC" and food antibiotic "Monenzin" normalize some biochemical blood indicators in cows in the transit period. At the same time, without correction of metabolic processes, cows are observed ketosis and acidosis, which can lead to premature disposal of animals from herd and as a result of economic losses. Thus, the use of the mixture is shown for the prevention and treatment of acidosis of the scar, metabolic acidosis, ketosis in cattle of the dairy direction of productivity.
Evaluation Yorkshire and Landrace breeds of pigs according to <i>PRKAG3</i>, <i>MC4R</i> and <i>MYOD1</i> marker genes
Authors: Balnikov A. , Gridyushko I. , Kazutova Yu. , Mikhailova M. , Romanishko E. 
Published: July 2021

Purpose: evaluation of pigs Yorkshire rocks and Landraz onPRKAG3, MC4RandMyOD1markers.Materials and methods. The paper presents the analysis of the results of genetic testing, and determines the frequency of alleles and genotypes of Yorkshire and Landrace breeds at the State Enterprise ZhodinoAgroPlemElita" of the Minsk region of the Republic of Belarus by the genes-markers of productive traits:PRKAG3, MC4RandMYOD1. Zootechnical and molecular genetic methods were used in the research (PCR/PDRF). Snapshot analysis was developed for the genotyping of pigs to detect polymorphic markers of meat-feeding productivity of pigs on the GenasPRKAG3, MyOD1, MC4R. At the first stage, there was an assessment of tribal young (173 heads) on its own productivity in terms of indicators: the age of achieving the living mass of 100 kg, the average daily increase (d) from birth to the live weight of 100 kg, the length of the body (cm), the lifetime meat quality of the thickness of the scrape (mm), height of the longest back muscles (mm), the content of meat in the body (%). At the second stage of the research, the controlling fastenings of 200 goals of pigs and evaluation of feedst and meat qualities in the following indicators were carried out: the age of achieving a living mass of 100 kg (days), the average daily increase (d), feed consumption per 1 kg of growth (to. Units). Also determined: the length of the carcass (cm), the slaughter output (%), the thickness of the spick over 6-7 breast vertebrae (mm), the area of "muscular eye" (cm2), the mass of the rear third of the half carcass (kg), the flow of meat in the carcus (%). Then, genetic studies were compared with productivity indicators.Results. As a result of the research, it was found that in the tested animals, the frequency of the preferred allele I-PRKAG3made 0.171-0.288, A-MC4R– 0.243-0.315, and C-MYOD1– 0.064-0.477, respectively. The developed comprehensive system for assessing the breeding value of Yorkshire and Landrace pigs based on the marker genesPRKAG3, MC4R, andMYOD1allowed us to identify the preferred alleles and determine correlation with productivity traits that provided increase in the average population values: for self-productivity - by 2-4%, for fattening traits - by 2.7-12.5%, for meat traits - by 2.8-34.4 %.Conclusion. The use of integrated system in pig breeding will speed up the selection work to increase the indicators of fattening and meat productivity of the created breeding herds of Yorkshire and Landrace pigs.