bluuebunny/crossref_metadata_2025_split huggingface dataset:
Randomize clinical trial of the effect of machined and rough surface of implant collar on crestal bone level and surrounding soft tissue
Authors: Chugh Anshul , Rani Sunita , Gupta Ambika 
Published: June 2021

Statement of Problem:
The importance of implant collar/neck in crestal bone area triggered the need to understand the influence of its design/surface topography on surrounding hard and soft tissues.

Purpose:
This study analyzed the effect of machined and rough surface of implant collar on bone level at crestal region and surrounding soft tissues in maxillary and mandibular anterior region.

Materials and Methods:
The clinical study was conducted on 20 participants (15 males and 5 females) based on the inclusion and exclusion parameters. Participants were broadly divided into two groups with 10 dental implants in Group R (implant with rough collar design) and Group M (implant with machined collar design). The participants were evaluated at baseline (within 1 week after implant placement), 3 months, and 6 months for crestal bone level and soft tissue parameters (pink esthetic score [PES]).

Results:
All implants showed clinically acceptable bone loss at interval of 6 months, i.e., 0.68 and 0.74 on mesial and distal aspect of R group implants, respectively, and 1.15 and 0.83 at mesial and distal aspect of R group implants, respectively. And also, the PES of all implants observed was above the clinical acceptability level, i.e., 6.15 and 6.05 for R and M groups implants, respectively.

Conclusion:
It can be concluded from the present study that there is no significant difference statistically in bone level at crestal region and soft tissues parameters in two different implant collar designs used in the study although the loss of bone observed was higher in machined group in comparison to rough group of implants and the PES observed was also more in R group in comparison to M group.
Evaluation of stress distribution in maxillary anterior bone from three different tapered implant thread designs with two angulated abutments
Authors: Attargekar Vikas , Galagali Girish , Reddy E Srinivas , Nidawani Prakash , Harsha R H , Naik Satyanarayana 
Published: June 2021

Background:
Tapered implants imitate the natural form of the root. They are known to enhance primary stability by providing pressure on the cortical bone of regions with poor bone qualities and also has a good survival rate as it directs stresses away from the crestal cortical bone while transferring it to the cancellous bone.

Purpose:
Maxillary anatomic constraints sometimes make it necessary to surgically position implants at angles that are not optimal for prosthetic restorations or by positioning the implant in the area with the greatest available bone, with the intention of correcting the implant alignment at the time of prosthetic restoration. This is made possible, in carefully planned cases with the use of angulated abutments.

Materials and Methods:
Three tapered implants with triangular, square, and buttress thread designs having a 15° and 25° angulated abutment were created. The implant models were positioned in anterior maxillary bone D2 and D3 and clinical loading conditions simulated. The maximum equivalent von Mises stress values were recorded and analyzed using ANSYS software.

Results:
The finite element analysis carried out showed less stresses from tapered implant square thread design in D2 and D3 bone with 15° angulated abutment, while buttress thread design performed better in D2 and D3 bone with 25° abutment angulation on axial and nonaxial loading.

Conclusion:
Bone type is an important factor that affects stress distribution. More stress occurred in D3 bone compared to D2 bone type. Thus, bone type should be carefully considered when choosing the most appropriate implant design.
Clinical evaluation of Chyawanprash as a preventive measure during the COVID-19 pandemic
Authors: Godatwar Pawan Kumar , Deshpande Shailesh , JoshiDeshmukh Pranita S. , Deshpande Vaishali Shailesh , Ghungralekar Raman , Tamoli Sanjay , Gupta Arun , Vedula Sasibhushan , Rugvedi Padmanabha , Kumar Rai Rajiva 
Published: June 2021

Background:

Chyawanprash is a classical Ayurveda polyherbal formulation that has proven immunomodulatory potential.

Aim:
The present clinical study was conducted to evaluate Chyawanprash for prophylaxis of COVID-19 infection.

Materials & Methods:
It was an Open-label, Multicentric, Randomized, Comparative, Prospective, and Interventional Community-based Clinical Study. The study was conducted at five sites across Maharashtra, Gujarat, and Rajasthan between May 2020 and November 2020.

Materials and Methods:
A total of 771 subjects were screened in the study; of whom, 721 subjects were randomized into two groups. Subjects in the DCP group who fell into the category of 13 years to 70 years were given Chyawanprash as a study intervention to be taken in a dose of one teaspoonful (approx. 12g) twice daily and children aged 5 to 12 years were given ½ teaspoonful (approx. 6g) twice daily followed by a cup of milk (approx. 200mL). Subjects in the control group were advised to consume one cup of milk (approx. 200mL) twice daily. The incidence of COVID-19 was assessed by reverse transcription polymerase chain reaction (RT-PCR)/antigen testing, which was conducted as per applicable guidelines and the severity of infection was assessed by using the World Health Organization (WHO) ordinal scale. The incidence and severity of non-COVID-19 infections was also assessed during the intervention period of 90 days.

Results:
Overall, 696 subjects completed the study, of whom 351 subjects were in the Chyawanprash (DCP) group and 345 were in the control group. In the DCP group, out of the 351 subjects who had completed the study, 42 were tested with RT-PCR/antigen and one subject was found to be positive for COVID-19. In the control group, out of the 345 subjects, 28 were tested with RT-PCR/Antigen and eight subjects were found to be positive for COVD-19. In the DCP group, the incidence was statistically significant lesser as compared with the control group. A total of 43 subjects in the control group and 41 subjects in the DCP group had symptoms of Influenza Like Illness (ILI). The DCP group also showed a statistically significant improvement in quality of life (QoL), as assessed by the Quality of Life Enjoyment and Satisfaction Questionnaire – Short Form (Q-LES-Q-SF) when compared with the control group.

Conclusion:
The outcome of the present study suggests and supports the prophylaxis potential of Chyawanprash as one of the preventive remedies for COVID-19 as recommended by the AYUSH fraternity. The beneficial effects may be due to the synergistic effects of the potent herbs that are known to have immune-boosting effects in healthy individuals.
Quercetin-3-O-β-D-glucuronide Inhibits Mitochondria Pathway-mediated Platelet Apoptosis via the Phosphatidylinositol-3-kinase/AKT Pathway in Immunological Bone Marrow Failure
Authors: Xia Le-Min , Zhang Ai-Ping , Zheng Qin , Ding Jie , Jin Zhe , Yu Hai , Wong Wan-Hui , Yu He-Ping 
Published: June 2021

Objective:
Quercetin-3-O-β-D-glucuronide (QG) can alleviate immunological bone marrow failure (BMF) by increasing platelet counts. However, the principal mechanism is less known. This study aimed at deciphering the possible underlying mechanism of QG that is indicated in thrombocytopenic purpura.

Methods:

In vitro and in vivo experiments were carried out for investigating the mechanism behind QG-facilitated inhibition of mitochondrial pathway-mediated excessive apoptosis of platelets through the phosphatidylinositol-3-kinase (PI3K)/AKT pathway.

Results:
Our results revealed that QG, the main effective ingredient of Herba Sarcandrae, increases the number of platelets and decreases the expression of Bax, Bad, Bid, and caspase-9 in immunological BMF, indicating the inhibition of mitochondrial pathway-mediated apoptosis. Moreover, we found that the protein and mRNA expressions, as well as the phosphorylated levels of PI3K and AKT, were increased significantly by QG, suggesting the activation of the PI3K/AKT pathway. Furthermore, the inhibition of the PI3K/AKT pathway by LY294002 antagonizes the effects of QG on platelet counts and mitochondrial pathway-mediated apoptosis.

Conclusion:
We demonstrate that QG inhibits the mitochondria pathway-mediated platelet apoptosis via the PI3K/AKT pathway in immunological BMF. This study thus sheds light on exploring the possible regulatory mechanism of traditional Chinese medicine in the treatment of thrombocytopenia induced by BMF.
Effects of cooling on the reproductive performance of gilts
Authors: Oyedeji J.O. , Imagbenikaro G.O. 
Published: June 2021

The study examined the effect of cooling on the reproductive performance of gilts using 27 Large White Experimental Gilts on a Completely Randomized Design (CRD) with 3 systems of cooling, namely Wallow Cooling (WC), Sprinkler Cooling (SC) and Zero Cooling (ZC). Gilts were weighed at the commencement of the experiment and thereafter fed ad libitum from service to farrowing. Feed intake till farrow, feed cost, gilt weight at farrow, date of farrow, litter size and weight were recorded. The feed/piglet weight, feed intake/litter, feed cost/litter and birth weight/piglet were derived. The results showed that feed intake per litter and feed per piglet weight were highest for gilts placed on WC(P< 0.05), followed by SC and least for sow placed on ZC; gilt weight before farrow was highest for sow placed on SC (69.78±0.92), followed by ZC (69.33±0.94) and least for gilts placed on WC (67.33±0.87); litter sizes of gilts placed under the WC and SC systems were similar (5.6±0.41) while that under the ZC system was comparatively smaller (5.4±0.40);while the date of farrow was lowest in the ZC system (113.8±0.32) followed by SC (114.0±0.33) and highest under the WC (114.1±0.33). However, the feed intake per litter, feed per piglet weight, litter sizes of gilts, birth weight per piglet of gilts and the average date of farrow among gilts placed on WC, SC and ZC were not statistically different at 5% level of significance. Though, there is no significant difference in the performance among gilts placed on WC, SC and ZC, temperature regulation through provision of efficient cooling system in piggery would help to increase litter size, improve feed intake per litter and reduce the average cost of feeding gilt per day in maximizing reproductive performances in pigs.Keywords: Cooling, gilts, service, farrow, piggery, litter size, piglet and birth weight
Hepatoprotective effects of ethanol extract of Caesalpiniabonduc against carbon tetrachloride induced hepatotoxicity in Albino Rats
Authors: Ubhenin A.E. , Igbe I , Adamude F.A. , Falodun A 
Published: June 2021

The present study was carried out to evaluate the Acute toxicity, hepatoprotective and in-vivo antioxidant activities of ethanolic extract of Caesalpinia bonduc leaf on carbon tetrachloride (CCl4) induced liver damage using Swiss albino rats . The ethanolic extract of the plant of C. bonduc were suspended in 5 % tragacanth and then administered orally at doses of 250 and 500 mg/kg body weight for fourteen days before intraperitoneally injection of Carbon tetrachloride (CCl4) at dose of 2 mL/kg body weight. The plant extracts at 250 and 500mg/kg b.wt showed a remarkable hepatoprotective and invivo antioxidant activities against carbon tetrachloride CCl4 – induced hepatotoxity judged from the serum marker enzymes .The CCl4 induced significant increase in aspartate amino transferase( AST), alanine amino transferase (ALT), alkaline phophatase (ALP), total bilirubin, and malondyaldehyde (MDA) with a reduction of total protein, catalase, and glutathione peroxidase . Treatment of rats with different doses of plant extract (250 and 500 mg/kg b.wt.) significantly (P< 0.001) altered serum maker enzymes and antioxidant levels to near normal levels. The study suggests that C. Bonduc specifically chloroform and ethyl acetate fraction may be good sources of natural antioxidant and hepatoprotective substance.Keywords: Ceasalpiniabonduc, hepatoprotective, intraperitoneally , antioxidant
Adsorption of Cu (II) onto bamboo supported manganese (BS-Mn) nanocomposite: effect of operational parameters, kinetic, isotherms, and thermodynamic studies
Authors: Dada Adewumi O. , Latona Dayo F. , Ojediran Olusegun J. , Nath Osazuwa O. 
Published: June 2021

Bamboo supported manganese (BS-Mn) nanocomposite was prepared in a single pot system via bottom-up approach using a chemical reduction method. Langmuir surface area, BET surface area, and Single pore surface area were 349.70 m2/g, 218.90 m2/g, and 213.50 m2/g, respectively. The pore size (24.34 Ȧ); pore volume (0.489 cm3); point of zero charge (5.8); bulk density (0.0035 gcm-3); specific surface area (33.00 m2/g) by Saer’s method and functional group of BS Mn nanocomposite determined using Fourier Transform Infrared Spectrophotometer (FTIR). Various operational parameters affecting adsorption of Cu(II) such as adsorbent dose (100 mg), pH (6), contact time (90 min), initial Cu(II) ions concentration (100 mg/L) and temperature (298 K) were determined in a batch technique. Kinetic data were best fitted to pseudo second-order model validated by sum of square error (SSE) and Chi-square test (χ2). Equilibrium data were better described by Langmuir isotherm model with the monolayer adsorption capacity surpassing those previously reported for Cu(II) uptake. The thermodynamic parameters, ΔGo (- 31.773 kJ mol-1), ΔSo (107.30 J) and ΔHo (+202 kJmol-1) revealed that the adsorption process was feasible, spontaneous and endothermic in nature. The study showed that BS–Mn is a promising nanocomposite which could be utilized for industrial wastewater remediation.Keywords: BS-Mn Nanocomposite; Copper; Adsorption; Kinetics; Isotherms; Spontaneous
Alkali Stresinin Farklı Mürdümük Geneotiplerinde (Lathyrus sativus L.) Çimlenme Gelişimine Etkisi
Authors: Medine ÇOPUR DOĞRUSÖZ  , Erdem GÜLÜMSER  , Uğur BAŞARAN  , Hanife MUT  
Published: June 2021

Bu çalışmada mürdümüğün (Lathyrus sativus L.) çimlenme üzerinde alkali stresinin etkileri incelenmiştir. Bitki materyali olarak 2006, 4403 ve 1603 yerel populasyonlar ile GAP Mavisi ve İptaş çeşitleri kullanılmıştır. Çalışmada alkali çözeltisi olarak sodyum karbonatın (Na2CO3) 6 farklı konsantrasyonu (0, 10, 20, 30, 40 ve 50 mM) uygulanmıştır. Çalışma bölünmüş parseller deneme desenine göre 3 tekerrürlü olarak kurulmuş olup, her genotipden 20 tohum petri içerisine konulmuş ve petrilere 10 ml Na2CO3 solusyonu eklenmiştir. Daha sonra petriler parafilm ile sıkıca kapatılmış ve iklimlendirme odasında karanlık ortamda 20±1°C’de 7 gün boyunca çimlenmeye bırakılmıştır. Denemede çimlenme hızı, çimlenme oranı, kök boyu, sürgün boyu, kök yaş ve kök kuru ağırlığı, fide güç indeksi ve ODAP içeriği incelenmiştir. İncelenen özellikler bakımından 1603 yerel populasyonu çeşitler kadar alkali stresine iyi cevap vermiştir. Uygulanan doz oranları bakımından ise 20 mM alkali dozunda dahi bitkilerin kabul edilebilir bir çimlenme gelişimine sahip olduğu görülmüştür. Ayrıca dozların artmasıyla birlikte ODAP içeriğinin azaldığı ve tüm genotiplerde ve dozlarda hayvan sağlığını olumsuz yönde etkileyecek düzeyin altında olduğu belirlenmiştir. Buna göre, mürdümüğün hafif alkali stresinden olumlu yönde etkilendiği belirlenmiş olup, çalışmadan elde edilene sonuçlar ileride yapılacak çalışmalara ışık tutacak niteliktedir.
The Impact of Drying Methods on Product Quality of Rosmarinus officinalis L.
Authors: Berfin SARIHAN  , Özlem TONÇER  
Published: June 2021

This study was conducted to evaluate the effects of different drying methods (shade drying, sun drying and oven drying at 40°C) on essential oil content, composition and color quality of rosemary (Rosmarinus officinalis L.). The essential oil content was obtained by hydro-distillation of dried plants, and were analyzed by GC-MS. The results showed that different drying methods had no significant effects on essential oil content, but essential oil constituents and percentage affected by drying methods as well. Camphor, (between 27.57 and 29.15%), 1.8 cineol (between 17.62 and 9.39%), borneol (11.25-12.37%) and linalool (between 7.30 and 8.18%) were the major essential oil compounds of different drying methods. In total regarding the essential oil composition, oven drying method can be recommended as the appropriate procedure for major constituents of rosemary essential oil. In this study, Lightness (L*), greenness (a*), and yellowness (b*) of dried leaves were also evaluated. Drying methods affected the color quality of the herb.
Editing New Testament Arabic Manuscripts in a TEI-base: fostering close reading in Digital Humanities
Authors: Clivaz Claire , Schulthess Sara , Sankar Martial 
Published: June 2021

Accepté pour un numéro spécial JDMDH (ed. M. Büchler et L. Mellerin); version finale (v4)
If one is convinced that " quantitative research provides data not interpretation " [Moretti, 2005, 9], close reading should thus be considered as not only the necessary bridge between big data and interpretation but also the core duty of the Humanities. To test its potential in a neglected field – the Arabic manuscripts of the Letters of Paul of Tarsus – an enhanced, digital edition has been in development as a progression of a Swiss National Fund project. This short paper presents the development of this edition and perspectives regarding a second project. Based on the Edition Visualization Technology tool, the digital edition provides a transcription of the Arabic text, a standardized and vocalized version, as well as French translation with all texts encoded in TEI XML. Thanks to another Swiss National Foundation subsidy, a new research project on the unique New Testament, trilingual (Greek-Latin-Arabic) manuscript, the Marciana Library Gr. Z. 11 (379), 12th century, is currently underway. This project includes new features such as " Textlink " , " Hotspot " and notes: HumaReC.
Applying ontologies to data integration systems for bank credit risk management
Authors: Elhassouni Jalil , Bazzi Mehdi , Qadi Abderrahim , Haziti Mohamed 
Published: June 2021

Special ISSUE VSST 2016
This paper proposes an ontological integration model for credit risk management. It is based on three ontologies; one is global describing credit risk management process and two other locals, the first, describes the credit granting process, and the second presents the concepts necessary for the monitoring of credit system. This paper also presents the technique used for matching between global ontology and local ontologies.
Desafíos de las Estrategias Pedagógicas Integradas (EPI) en la formación de profesores y profesoras de Educación Física en Chile (Challenges of integrated learning Strategies (ILS) in a Physical Education teaching training program in Chile)
Authors: Navarro Aburto Braulio Ademir , Peña Trocoso Sebastián , Beltrán Juan Carlos , Guzmán Muñoz Adolfo , Flores Ferro Elizabeth , Fuentes Merino Paola 
Published: June 2021

Los esfuerzos que desarrolla el contexto universitario en Chile en la formación de profesores de educación física vinculados a las Estrategias Pedagógicas Integrada (EPI) son plausibles, pero, se plantea que toda propuesta pedagógica para alcanzar el rango de calidad necesita ser evaluada, lo que permite cumplir con los objetivos que generaron su creación. El objetivo del estudio fue identificar los obstáculos y desafíos que profesores y estudiantes de la carrera de pedagogía en educación física de una universidad en Chile, manifiestan de la EPI. La metodología utilizada estuvo dada por el enfoque cualitativo. La principal técnica de recolección de datos se realizó a través de la entrevista en profundidad. Para la reducción de los datos cualitativos se utilizó el software ATLAS Ti. 7.5. Los participantes de este estudio fueron diez estudiantes y diez profesores de la carrera de Pedagogía Educación Física en Temuco, Chile. Los principales resultados manifiestan, falta de articulación docente y el trabajo colaborativo entre el estudiantado que permite articular el trabajo en el proceso de la EPI. Como conclusión se manifiesta que es necesario dejar de lado la mirada técnica del proceso que lleva a enfocar la EPI solo en los resultados, haciendo énfasis en el proceso EPI que enriquece la formación docente en la praxis educativa.
Abstract. Efforts developed in the university context in Chile regarding physical education (PE) teaching training linked to integrated learning strategies (ILS) are plausible. However, it is stated that all proposed pedagogical approaches, to reach a high standard quality, require assessment to allow them to accomplish the objectives that prompted their creation. The aim of this study was to identify the obstacles and challenges that professors and students have encountered related to ILS in a PE training program from a Chilean university. The methodology employed was based on the qualitative approach and the main data collection tool was an in-depth interview. ATLAS ti. 7.5 software was used to reduce and define the qualitative data gathered. The participants of this research were 10 students and 10 professors from a PE teaching training program in Temuco, Chile. Results show the main obstacles and challenges for ILS are associated with a lack of structured teaching approach and of collaborative work among the student body, which allow efficient management of the ILS working process. As a conclusion, it is stated the need to put aside the technical approach focusing ILS only on results, to give emphasis instead to the ILS process, which enriches teaching training in the educational praxis.
Comparison of Efficacy of Nasal Septal Splints with Clip versus Nasal Packing after Septoplasty
Authors: Singh Piyush Kant , Singh Preeti 
Published: June 2021

Introduction
It has always been a concern of ENT surgeon to prevent post operative complications like nasal bleeding, septal hematoma and septal abscess after septoplasty. Traditionally nasal packing has been done to avoid these complications. Although the nasal pack itself has been a concern for several reasons, packing apart from causing breathing distress, has resulted in epiphora, dysphagia, sleep disturbance, post-operative pain, headache, septal infection, septal abscess and even toxic shock syndrome.
Materials and Methods
This study has compared the efficacy of a newly designed septal splint with clip with nasal packs. This study was done on 60 patients, nasal packing was done in 30 patients and septal splints with clip were applied in 30 patients.
Results
Post-operative pain, epiphora, dysphagia, dryness of mouth and sleep disturbance was found to be significantly less in patients with septal splints with clip as compared to those with nasal packing.
Conclusion
Septal splints with clip is more efficacious alternative to nasal packing in patients undergoing septoplasty.