bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ventilator-Associated Pneumonia Bundle of Care Training of Nursing Officers Using Simulation and Its Impact on Their Knowledge and Incidence of Ventilator-Associated Pneumonia: A Quasi-Experimental Study
Authors: Jeengar Ravi Kumar , Choudhary Bharat , Khera Daisy , Singh Simranjeet , Purohit Suray Prakash , Singh Kuldeep 
Published: December 2021

AbstractThe objective of this study was to assess the effectiveness of simulation-based training (SBT) of a ventilator-associated pneumonia (VAP) bundle of care on the knowledge and practice of nursing officers working in the pediatric intensive care unit (PICU) and its impact on the incidence of VAP. This study was a single-center, pre- and postsimulation-based educational interventional tool conducted in a six-bed PICU located in Western Rajasthan, India. Thirty nursing officers working in the PICU participated in the study. Baseline knowledge and practice regarding VAP bundle of care were assessed using a questionnaire and practice checklist. It was followed by 1:1 SBT of the VAP bundle of care following which all participants were immediately reassessed and then again at 3 months postintervention. The incidence of VAP (events/1,000 ventilation days) was subsequently compared both at 6 months pre- and postintervention. Thirty nursing officers participated in the study of which 63% were male. Baseline knowledge and practice increased significantly immediately after the VAP bundle of care training and then again at 3 months in comparison to preintervention testing (baseline 20.27 ± 4.51, immediate postintervention 26.0 ± 3.67, 3 months postintervention 23.97 ± 4.69). The incidence of VAP showed a declining trend from 46.1 to 36.5/1,000 ventilation days; however, this finding was not statistically significant (p = 0.22). The simulation-based teaching program significantly enhanced nursing officers' knowledge and practice toward utilization of a preventive VAP bundle of care. There was decay in knowledge with time indicating that repetitive sessions are required at regular intervals to sustain this effect.
Why ex post peer review encourages high-risk research while ex ante review discourages it
Authors: Gross Kevin , Bergstrom Carl T. 
Published: December 2021

Significance
Science operates within social structures that govern and shape scientific activity. One such institution is peer review, which focuses attention on promising and interesting science while encouraging scientists to pursue some questions instead of others. Here, we show that ex ante review of proposals for future work and ex post review of completed science create different incentives for researchers. This tension creates a dilemma, because most researchers need to find projects that will survive both ex ante and ex post peer review. By unpacking this dynamic, we can understand how peer review shapes scientific activity and how changes to peer review might take science in unforeseen directions.
Leveraging nonstructural data to predict structures and affinities of protein–ligand complexes
Authors: Paggi Joseph M. , Belk Julia A. , Hollingsworth Scott A. , Villanueva Nicolas , Powers Alexander S. , Clark Mary J. , Chemparathy Augustine G. , Tynan Jonathan E. , Lau Thomas K. , Sunahara Roger K. , Dror Ron O. 
Published: December 2021

SignificanceStructure-based drug design depends on the ability to predict both the three-dimensional structures of candidate molecules bound to their targets and the associated binding affinities. We demonstrate that one can substantially improve the accuracy of these predictions using easily obtained data about completely different molecules that bind to the same target without requiring any target-bound structures of these molecules. The approach we developed to integrate physical and data-driven modeling may find a variety of applications in the rapidly growing field of artificial intelligence for drug discovery.
Absorbing narratives and Motivation to Read
Authors: Rosa Lotta-Sofia La , Lehtimäki Aku-Ville 
Published: December 2021

AbstractDigital reading has established its position, and thus research on how reading mode affects reading experience and enjoyment is needed. This study is based on a reading experiment with 89 14–15-year-olds who read or listened to an entire book in four different reading modes: paperbook, ebook, audiobook, and via a commercial subscription service. Using quantitative methods, we examine whether reading mode affects story world absorption as well as seek connections between gender, motivation, absorption and reading mode preferences. Based on the study, reading mode has no statistical impact on narrative absorption experience, measured by the Story World Absorption Scale. Instead, the experience correlates with reading motivation; an adolescent with higher motivation is more likely to feel absorbed while reading, regardless of reading mode. On average, girls experience higher reading motivation and absorption than boys. Less motivated seem to prefer audiobook whereas more motivated choose reading over listening.
An investigation into the relationship between fiction and nonfiction reading exposure, and factors of critical thinking
Authors: Hollis Helena 
Published: December 2021

Abstract
Reading fiction has been associated with improved social and imaginative reasoning that could lead to improved critical thinking. This observational study investigated the relationship between fiction and nonfiction exposure, narrative transportation, and factors of critical thinking (critical thinking disposition, and epistemological orientation). Self-selecting participants (N = 335) completed an online survey including an author recognition test and self-report scales. Fiction scores were significantly associated with higher critical thinking disposition, while nonfiction had an inverse effect correlating with lower disposition. Fiction reading was associated with decreased absolutism, and nonfiction score conversely with higher absolutism. Total and nonfiction print exposure were associated with lower multiplism, with no significant association for fiction. Total and fiction print exposure were associated with higher evaluativism, with no significant association for nonfiction. Narrative transportation mediated some of these relationships. These findings provide a basis for further research into reading fiction and nonfiction, and critical thinking.
Biaxial film bulk acoustic resonator magnetic sensor based on the Fe80Ga20 anisotropic ΔE effect
Authors: Yun Xiaofan , Lin Wenkui , Hu Rui , Wang Xiaoyi , Zeng Zhongming , Zhang Xinping , Zhang Baoshun 
Published: December 2021

Abstract
With the increasing application of personal navigation systems in consumer electronics, the demand for multi-axis magnetic sensors based on MEMS is growing. We report a biaxial MEMS DC magnetic sensor consisting of an Mo/AlN/Fe80Ga20 film bulk acoustic resonator, with anisotropy ΔE effect-based sensing principle. Different from the previously reported 1D magnetic sensor based on the ΔE effect, the anisotropic ΔE effect was used to realize in-plane and out-of-plane 2D magnetic field responses on a discrete sensor, and the sensor had two readout methods: resonant frequency f and return loss S11. The magnetic sensor realized the resonant frequency f shifted by 1.03 MHz and 0.2 MHz in the 567 Oe in-plane magnetic field and 720 Oe out-of-plane magnetic field, respectively, and the S11 changes by −30.2 dB and −0.92 dB. As the applied magnetic field increases, the −3 dB bandwidth quality factor Q
3dB of the S11 curve gradually increases, and its maximum values in the in-plane and out-of-plane magnetic fields are 77 143 and 1828, respectively, which reduces the detection limit of the magnetic sensor. The resonant magnetic sensor has stable high linear temperature and frequency drift characteristics, and its temperature frequency coefficient is −48.7 ppm °C−1.
Qualitative analysis and new soliton solutions for the coupled nonlinear Schrödinger type equations
Authors: Elbrolosy M E 
Published: December 2021

Abstract
This work is interested in constructing new traveling wave solutions for the coupled nonlinear Schrödinger type equations. It is shown that the equations can be converted to a conservative Hamiltonian traveling wave system. By using the bifurcation theory and Qualitative analysis, we assign the permitted intervals of real propagation. The conserved quantity is utilized to construct sixteen traveling wave solutions; four periodic, two kink, and ten singular solutions. The periodic and kink solutions are analyzed numerically considering the effect of varying each parameter keeping the others fixed. The degeneracy of the solutions discussed through the transmission of the orbits illustrates the consistency of the solutions. The 3D and 2D graphical representations for solutions are presented. Finally, we investigate numerically the quasi-periodic behaviour for the perturbed system after inserting a periodic term.
Anti-fungal therapy via incorporation of nanostructures: A systematic review for new dimensions
Authors: Younus Ishrat , Khan Sarah Jameel , Maqbool Sidra , Begum Zubia 
Published: December 2021

AbstractBackground.Fungal infections are one of the most prevailing worldwide public health issues. Despite the commercially available antifungal drugs, side effects associated with these agents and resistance may lead to the development of antifungal drugs by using advanced technology. The mainbody of the abstract.In the current era, nanotechnology is one of the most predominant techniques with massive advantages in the field of medicines and medical sciences. In the last two decades, various nanostructures were developed based on metals, plants, and microorganisms. The aim of the review is to discuss all original researches and to review articles of the last two decades, including earlier and recent development in different types of nanostructures as an antifungal therapy. Published papers in the English language were searched and reviewed from the online databases from January 2007 till May 2021. The search engines included were PubMed, Google, Google scholar, and Sciencedirect. In all the databases, the keywords ‘fungi’, ‘antifungal’, ‘nanomaterials’, ‘nanostructures’, and ‘nanotechnology’ were used for literature search.Short conclusion. The innovative nanostructures are vital for the treatment of different strains of fungal infections i.e. from minor nail infections to major systemic fungal infections. Additionally, nanostructures also enhance the efficacy, solubility, penetration, and drug release to the targeted site of conventional antifungal agents.
Removing fiber orientation uncertainty from the finite element model of a composite lamina with direct updating algorithm
Authors: Chhipa Sajid Mohammad , Kumar Pramod , Bagha Ashok Kumar , Bahl Shashi 
Published: December 2021

Abstract
In this paper, a direct updating algorithm is proposed to remove the uncertainties present in the simulated/analytical finite element (FE) model of a composite material lamina. There are number of possible uncertainties present in the composite materials such as its constituent properties and its orientations, boundary conditions and its assumed dimensions etc It is observed from this analytical study that the uncertainty present in the fiber orientation in the matrix put its direct effect on the modal-model (natural frequencies and corresponding mode shapes) of the composite material lamina. The direct updating algorithm has been already used for many isotropic structures. However, for anisotropic structures like composite materials, the application to accurate the simulated-finite element model by using finite element model updating techniques is a new area of research. In this regard, to remove these uncertainties from the simulated-finite element model of a composite lamina, the application of direct updating algorithm is proposed. It is observed from the present study that by updating the mass and the stiffness matrices through direct updating algorithm, the vibration pattern of the mode shapes are updated. It is found that the maximum percentage error in the constituent properties and in the fiber orientation is 22.58% and 100% respectively that are reduced to 0% in the modal-model of the lamina by the application of direct updating algorithm. This represents the novelty of the application of direct updating method for composite lamina structures. The overlay of frequency response function (FRF) curves are plotted to authenticate the results. Also, it is found that the application of the direct updating algorithm increases the tracking performance of the simulated FE model response when excited at different resonant frequencies.
Constraining dark matter annihilation with cosmic ray antiprotons using neural networks
Authors: Kahlhoefer Felix , Korsmeier Michael , Krämer Michael , Manconi Silvia , Nippel Kathrin 
Published: December 2021

Abstract
The interpretation of data from indirect detection experiments searching for dark matter annihilations requires computationally expensive simulations of cosmic-ray propagation. In this work we present a new method based on Recurrent Neural Networks that significantly accelerates simulations of secondary and dark matter Galactic cosmic ray antiprotons while achieving excellent accuracy. This approach allows for an efficient profiling or marginalisation over the nuisance parameters of a cosmic ray propagation model in order to perform parameter scans for a wide range of dark matter models. We identify importance sampling as particularly suitable for ensuring that the network is only evaluated in well-trained parameter regions. We present resulting constraints using the most recent AMS-02 antiproton data on several models of Weakly Interacting Massive Particles. The fully trained networks are released as DarkRayNet together with this work and achieve a speed-up of the runtime by at least two orders of magnitude compared to conventional approaches.
Analysis on non-stationary gyroscopes and their application in measurement technology
Authors: Andreev A I , Perekrestov A P 
Published: December 2021

Abstract
In this work, the main subjects of research are: 1) analysis of the process of rotation of a Chinese top on a flat surface, 2) analysis of the main dependencies and an explanation of the rise of the center of gravity of the top during rotation due to nonlinear friction and the resulting force of the overturning top on the upper axis. Also, an analytical study of the motion of the top along the plane and the laws of rotation was carried out, the rotation of the top was analyzed from the point of view of asymmetry during rotation. The top-top spinning top is an interesting case of raising the center of gravity during rotation. The simplest model of a Chinese top can be a dynamic symmetric inhomogeneous ball, the center of mass of which lies on the axis of dynamic symmetry, but does not coincide with its geometric center. The precession of the Chinese top is based on dry friction. The occurrence of a gyroscopic deflection moment is based on the frictional force. Considering the simplest top-type top, one can distinguish the main forces acting on this body, as well as its characteristics that determine the precession. Based on this fact, it is possible to propose the use of this body of revolution as a working medium for instruments such as tribometers and gravimeters. In the first case, this makes it possible to increase the accuracy of the device, in the second, to create a new scheme for measuring gravitational fields. The relevance of this work is the analysis of the rotation of the Chinese top and the possibility of its use in measuring instruments.
Diffuse reflectance photometric system for noninvasive blood glucose control
Authors: Pozhar K V , Mikhailov M O , Polyakova E A , Litinskaia E L 
Published: December 2021

Abstract
The paper considers the method of diffuse reflectance spectroscopy for noninvasive glucose level measuring in biological tissues. It is proposed a portable implementation of the system, based on a laser diode with a wavelength of 1600 nm and a power of 30 mW, operating in a pulsed mode, as well as a set of NIR-photodiodes located around the laser. The measuring system has been tested on model solutions with diffuse reflectance from polystyrene and pigskin. In the course of measurements on fixed system, an error of ~17 mg/dl is observed, which can be reduced by improving miniature laser sources.
Analysis and regulation of the cardiovascular system of univentricular heart with different configurations of the total cavopulmonary connection
Authors: Galiastov A A , Telyshev D V 
Published: December 2021

Abstract
The cardiovascular system (CVS) is a complex mechanism capable of reacting and regulating various changes in external and internal parameters. A particular problem is the study of CVS with univentricular heart. We studied the hemodynamic response of the CVS to the use of various configurations of bypassing the right side of the heart. During our research, we selected three different configurations of the total cavopulmonary connection. All configurations were made from Clear Flex 50 and tested in an experimental workbench. According to the research results, the TCPC-3 configuration is the most optimal. It has symmetrical output values of flows and pressures and there is no significant increase in inlet pressure. The results of this study can be used to optimize the control of the parameters of the ventricular assist device and the total artificial heart.
Using atomic force microscopy to work with the cell surface of Candida albicans
Authors: Filippova E M , Nesvizhski U V , Titov S A , Glukhov A I 
Published: December 2021

Abstract
Candida albicans is a yeast-like fungus that lives on human mucous membranes and skin and does not cause infections. However, it plays a role in the development of opportunistic infections in immunocompromised people. In this work, we would like to evaluate the possibility of studying the cell wall of C. albicans by atomic force microscopy, as well as compare the operating modes of the microscope and choose optimal one for working with the fungus. Atomic force microscopy is a powerful tool for evaluating surfaces, including the cell walls of biological objects. The microscope is capable of operating in different modes, but in this study we compared two of them: contact and semi-contact. These methods are the most popular for evaluating the surfaces of biological objects. Comparison of the modes was carried out on the C. albicans strain. The surface of the strain was scanned by atomic force microscopy, and the curves of the dependence of the sensor deviation from the distance to the object were recorded. Scanning and recording of curves were carried out in two modes of operation of the microscope: contact and semi-contact, as well as three sensors: soft, medium and hard.
Spatio-temporal analysis the results of solving the inverse problem of electrocardiography
Authors: Shcherbakova A I , Kupriyanova Y A , Zhikhareva G V 
Published: December 2021

Abstract
The results of the development and testing an algorithm for the physiological interpretation the results of solving the inverse problem of electrocardiography are presented. The solution to the inverse problem of electrocardiography is the distributions of equivalent current sources on the quasi-epicardium, restored from the electric potentials created by the heart on the surface of the chest. The developed algorithms are based on the space-time analysis of the distributions of equivalent current sources on the quasi-epicardium. The development and testing of the algorithm was carried out using a simulation model of the electrical activity of the heart based on cellular automata. The efficiency of the algorithm has been demonstrated when simulating the electrical activity of the heart in normal conditions, as well as in the presence of pathological changes in the myocardium in the form of areas with delayed conduction of excitation.
The effect of queue size on the throughput, in group failure mode, for the loaded transport channel
Authors: Karim P H , Ghafoor J K , Suschenko S P 
Published: December 2021

Abstract
The external data flow decreases the throughput of the transport connection. The indicator of this external load is the queue size in front of the protocol data. In this article, using a mathematical model in analytical and numerical forms, the relation between the throughput of the channel and the protocol parameters are presented including the queue size parameter. In this work the effect of the queue size on time-out duration has been shown, which is one of the important parameters and it’s studied weakly in researches. Also, the relation between round-trip delay, the reliability of the transmission of the information segments with queue size are also shown.
Groups of mobile cellular service stations for operational radio communication tasks in remote areas
Authors: Pishchin O N , Puzankov D S , Perova K V , Chulkov I O 
Published: December 2021

Abstract
The authors of the article consider solutions needed to organize mobile cellular communication systems in remote areas. Modern mobile stations do not have the capability to overcome marshy areas, steppe, heavily rugged reliefs of the desert, water barriers and forests. Moreover, the coverage area from one base station is not highly localized (radio coverage area is not significant). Furthermore, modern mobile communication facilities have poor autonomy. The article proposes measures for an operational organization of cellular communications in large remote areas with a coverage radius of a medium-sized city. Article also considers the issues posed by a temporary organization of communication service in large sections near important locations (pipelines, riverbeds, transport and railway lines). The need for such an operational usage of mobile communication systems is most associated with geological exploration and scientific research in large remote areas and large areas with a damaged communication system due to natural emergencies or military operations.
The method for constructing fault-tolerant photonic switches for high-performance computing systems
Authors: Barabanova E A , Vytovtov K A , Vishnevsky V M , Podlazov V S 
Published: December 2021

Abstract
In this paper the new type of fault-tolerant non-blocking photonic switch is presented for the first time. The proposed switch architecture is based on quasi-complete graph topology which use provides non-blocking and fault-tolerant switching process. The new two-stage switch architecture uses the stage of dual photonic switches and pairs of photonic demultiplexers and multiplexers which have been described in detail by authors in their previous works. Depending on the number of different backup connections, the two types of fault-tolerant pho-tonic switches are considered in this paper: single-channel fault-tolerant photonic switch and dual-channel fault-tolerant photonic switch. The mathematical expressions for calculating the switching and fiber complexities of these two types of fault-tolerant photonic switches are also presented here for the first time. The numerical calculations shown that the increasing the reliability of the fault-tolerant photonic switches twice leads to an increasing their switching complexity in 1.4 times and fiber complexity in 1.8 times.