bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhanced Recovery After Surgery strategies for elective craniotomy: a systematic review
Authors: Stumpo Vittorio , Staartjes Victor E. , Quddusi Ayesha , Corniola Marco V. , Tessitore Enrico , Schröder Marc L. , Anderer Erich G. , Stienen Martin N. , Serra Carlo , Regli Luca 
Published: May 2021

OBJECTIVE
Enhanced Recovery After Surgery (ERAS) has led to a paradigm shift in perioperative care through multimodal interventions. Still, ERAS remains a relatively new concept in neurosurgery, and there is no summary of evidence on ERAS applications in cranial neurosurgery.

METHODS
The authors systematically reviewed the literature using the PubMed/MEDLINE, Embase, Scopus, and Cochrane Library databases for ERAS protocols and elements. Studies had to assess at least one pre-, peri-, or postoperative ERAS element and evaluate at least one of the following outcomes: 1) length of hospital stay, 2) length of ICU stay, 3) postoperative pain, 4) direct and indirect healthcare cost, 5) complication rate, 6) readmission rate, or 7) patient satisfaction.

RESULTS
A final 27 articles were included in the qualitative analysis, with mixed quality of evidence ranging from high in 3 cases to very low in 1 case. Seventeen studies reported a complete ERAS protocol. Preoperative ERAS elements include patient selection through multidisciplinary team discussion, patient counseling and education to adjust expectations of the postoperative period, and mental state assessment; antimicrobial, steroidal, and antiepileptic prophylaxes; nutritional assessment, as well as preoperative oral carbohydrate loading; and postoperative nausea and vomiting (PONV) prophylaxis. Anesthesiology interventions included local anesthesia for pin sites, regional field block or scalp block, avoidance or minimization of the duration of invasive monitoring, and limitation of intraoperative mannitol. Other intraoperative elements include absorbable skin sutures and avoidance of wound drains. Postoperatively, the authors identified early extubation, observation in a step-down unit instead of routine ICU admission, early mobilization, early fluid de-escalation, early intake of solid food and liquids, early removal of invasive monitoring, professional nutritional assessment, PONV management, nonopioid rescue analgesia, and early postoperative imaging. Other postoperative interventions included discharge criteria standardization and home visits or progress monitoring by a nurse.

CONCLUSIONS
A wide range of evidence-based interventions are available to improve recovery after elective craniotomy, although there are few published ERAS protocols. Patient-centered optimization of neurosurgical care spanning the pre-, intra-, and postoperative periods is feasible and has already provided positive results in terms of improved outcomes such as postoperative pain, patient satisfaction, reduced length of stay, and cost reduction with an excellent safety profile. Although fast-track recovery protocols and ERAS studies are gaining momentum for elective craniotomy, prospective trials are needed to provide stronger evidence.
Endovascular treatment for calcified cerebral emboli in patients with acute ischemic stroke
Authors: Bruggeman Agnetha A. E. , Kappelhof Manon , Arrarte Terreros Nerea , Tolhuisen Manon L. , Konduri Praneeta R. , Boodt Nikki , van Beusekom Heleen M. M. , Hund Hajo M. , Taha Aladdin , van der Lugt Aad , Roos Yvo B. W. E. M. , van Es Adriaan C. G. M. , van Zwam Wim H. , Postma Alida A. , Dippel Diederik W. J. , Lingsma Hester F. , Marquering Henk A. , Emmer Bart J. , Majoie Charles B. L. M. , _ _ 
Published: May 2021

OBJECTIVE
Calcified cerebral emboli (CCE) are a rare cause of acute ischemic stroke. The authors aimed to assess the association of CCE with functional outcome, successful reperfusion, and mortality. Furthermore, they aimed to assess the effectiveness of intravenous alteplase treatment and endovascular treatment (EVT), as well as the best first-line EVT approach in patients with CCE.

METHODS
The Multicenter Randomized Controlled Trial of Endovascular Treatment for Acute Ischemic Stroke in the Netherlands (MR CLEAN) Registry is a prospective, observational multicenter registry of patients treated with EVT for acute ischemic stroke in 16 intervention hospitals in the Netherlands. The association of CCE with functional outcome, reperfusion, and mortality was evaluated using logistic regression models. Univariable comparisons were made to determine the effectiveness of intravenous alteplase treatment and the best first-line EVT approach in CCE patients.

RESULTS
The study included 3077 patients from the MR CLEAN Registry. Fifty-five patients (1.8%) had CCE. CCE were not significantly associated with worse functional outcome (adjusted common OR 0.71, 95% CI 0.44–1.15), and 29% of CCE patients achieved functional independence. An extended Thrombolysis in Cerebral Infarction score ≥ 2B was significantly less often achieved in CCE patients compared to non-CCE patients (adjusted OR [aOR] 0.52, 95% CI 0.28–0.97). Symptomatic intracranial hemorrhage occurred in 8 CCE patients (15%) vs 171 of 3022 non-CCE patients (6%; p = 0.01). The median improvement on the National Institutes of Health Stroke Scale (NIHSS) was 2 in CCE patients versus 4 in non-CCE patients (p = 0.008). CCE were not significantly associated with mortality (aOR 1.16, 95% CI 0.64–2.12). Intravenous alteplase use in CCE patients was not associated with functional outcome or reperfusion. In CCE patients with successful reperfusion, stent retrievers were more often used as the primary treatment device (p = 0.04).

CONCLUSIONS
While patients with CCE had significantly lower reperfusion rates and less improvement on the NIHSS after EVT, CCE were not significantly associated with worse functional outcome or higher mortality rates. Therefore, EVT should still be considered in this specific group of patients.
Tumor location and reduction in functional MRI estimates of language laterality
Authors: Połczyńska Monika M. , Beck Lilian , Kuhn Taylor , Benjamin Christopher F. , Ly Timothy K. , Japardi Kevin , Cavanagh Lucia , Bookheimer Susan Y. 
Published: May 2021

OBJECTIVE
Brain tumors located close to the language cortex may distort functional MRI (fMRI)–based estimates of language dominance. The nature of this distortion, and whether this is an artifact of numerous confounders, remains unknown. The authors hypothesized tumor bias based on laterality estimates independent of confounders and that the effects are the greatest for tumors proximal to Broca's area.

METHODS
To answer this question, the authors reviewed more than 1113 patients who underwent preoperative fMRI to match samples on 11 known confounders (tumor location, size, type, and grade; seizure history; prior neurosurgery; aphasia presence and severity; and patient age, sex, and handedness). The samples included 30 patients with left hemisphere tumors (15 anterior and 15 posterior) and 30 with right hemisphere tumors (15 anterior and 15 posterior), thus totaling 60 patients (25 women; 18 left-handed and 4 ambidextrous; mean age 47 [SD 14.1] years). Importantly, the authors matched not only patients with left and right hemisphere tumors but also those with anterior and posterior tumors. Standard fMRI laterality indices (LIs) were calculated using whole-brain and region of interest (ROI) approaches (Broca's and Wernicke's areas).

RESULTS
Tumors close to Broca's area in the left hemisphere decreased LIs independently of known confounders. At the whole-brain level, this appeared to reflect a decrease in LI values in patients with left anterior tumors compared with patients with right anterior tumors. ROI analysis replicated these findings. Broca's area LIs were significantly lower (p = 0.02) in patients with left anterior tumors (mean LI 0.28) when compared with patients with right anterior tumors (mean LI 0.70). Changes in Wernicke's area–based LIs did not differ as a function of the tumor hemisphere. Therefore, in patients with left anterior tumors, it is essential to assess language laterality using left posterior ROIs. In all remaining tumor groups (left posterior tumors and right hemisphere tumors), language laterality derived from the anterior language ROI was the most robust measure of language dominance.

CONCLUSIONS
Patients with tumors close to Broca's area showed more bilateral fMRI language maps independent of known confounders. The authors caution against the assumption that this reduced language laterality suggests no or little risk to language function following tumor resection in the left inferior frontal gyrus. Their results address how to interpret fMRI data for neurosurgical purposes, along with theoretical questions of contralesional functional compensation and disinhibition.
Strategi Pembelajaran Model Blended Learning Solusi Keterbatasan Dosen
Authors: Pongantung Henny , Elmiana B Linggi  , Asrijal Bakri  , Pricilia Tore  
Published: May 2021

STIK Stella maris saat ini mengunakan metode pembelajaran konvensional dengan metode student center learning (SCL). Hal ini cukup memberatkan dosen karena tenaga dosen cukup terbatas. Dengan melihat kondisi ini, peneliti mengusulkan solusi dengan menggunakan metode pembelajaran blended learning agar mahasiswa lebih banyak mendapatkan pengalaman belajar mandiri sesuai konsisi mahasiswa dan waktu yang digunakan dosen untuk masuk di kelas bisa dialihkan secara online. Tujuan penelitian menganalisis perbedaan pembelajaran metode blended learning dan metode konvensional terhadap peningkatan motivasi belajar mahasiswa di STIK Stella Maris Makassar. Penelitian ini adalah jenis quasy-eksperiment mengunakan rancangan pre- post test control group design. Teknik pengambilan sampel yaitu total sampling, jumlah sampel 200 mahasiswa, dibagi dalam kelompok intervensi dan kontrol. Teknik analisis data menggunakan uji Mann Whitney. Diperoleh hasil P=0,000;?=0,005 maka Ha diterima Ho ditolak. Hal ini menunjukkan perbedaan antara metode konvensional dan blended learning. Maka dapat disimpulkan bahwa metode blended learning dapat meningkatkan motivasi belajar mandiri pada mahasiswa dari pada metode konventional. Dari penelitian ini disarankan metode blended learning dapat diterapkan di STIK Stella Maris khususnya dan seluruh perguruan tinggi terutama dengan jumlah dosen yang terbatas.
Influence of posterior tibial slope on three-dimensional femorotibial alignment under weight-bearing conditions in healthy Japanese elderly people
Authors: Katsumi Ryota , Sato Takashi , Mochizuki Tomoharu , Watanabe Satoshi , Tanifuji Osamu , Kawashima Hiroyuki 
Published: May 2021

BACKGROUND: Assessment of three-dimensional (3D) femorotibial alignment is essential for successful knee osteoarthritis treatment in the elderly. The complex morphology of the posterior tibial slope (PTS) might have an influence on sagittal and rotational alignment and the positional relationship between the femur and tibia in the anterior–posterior (AP) direction under weight-bearing conditions. OBJECTIVE: This study aimed to clarify the association between the PTS and 3D femorotibial alignment under weight-bearing conditions in healthy Japanese elderly individuals. METHODS: We investigated the 3D femorotibial alignment of 110 lower extremities of 55 healthy individuals (26 women, 29 men, mean age: 70 ± 6 years). Using our previously reported 3D-to-2D image registration technique, we evaluated the 3D hip-knee-ankle angle (3DHKA) in the sagittal plane, rotational alignment, and the distance between the femoral and tibial origins in the AP direction (tibial AP position) as femorotibial alignment parameters under weight-bearing conditions. We assessed the medial and lateral PTS and their angular difference (PTS difference) as PTS parameters. Stepwise multiple linear regression analysis was performed using PTS parameters and other possible confounders (age, sex, height, and weight) as the independent variables and femorotibial alignment parameters as the dependent variable. RESULTS: Weight (𝛽 = 0.393, p < 0.001) and lateral PTS (𝛽 = 0.298, p < 0.001) were the predictors associated with 3DHKA in the sagittal plane. Lateral PTS (𝛽 = 0.304, p = 0.001) was the only predictor associated with the tibial AP position. Sex (𝛽 = −0.282, p = 0.002) and PTS difference (𝛽 = −0.231, p = 0.012) were associated with rotational alignment. CONCLUSIONS: We found that a steeper lateral PTS resulted in a more flexed knee and anterior tibia. The PTS difference was positively correlated with tibial external rotation. Our data could be used as the standard reference for realignment surgery to ensure PTS is appropriately maintained.
Air distribution in convex wall jets for ventilation with a constant air flow
Authors: Korbut V. , Mileikovskyi Viktor 
Published: May 2021

The scheme of air exchange organization using air supply above a working zone by convex wall jets that interact with each other has been substantiated. This scheme is advisable in cases where it is impossible to supply air directly to the working zone. It provides optimal microclimate parameters with minimal recirculation of polluted air from the upper zone. Simulation of the air exchange organization in an exhibition hall in International Exhibition Centre in Kyiv with ventilation at a constant air volume (CAV) has been performed. The floor area is 5258 m2, the height is 19 m, the minimum outdoor air flow is 21.667 m3/s (78000 m3/h). The current design scheme of air exchange organization is zonal. General air exchange is 43.3333 m3/s (156000 m3/h). Recirculation is accepted 50 %. The air flow supplied in the upper and middle zones is, respectively, 22.5 m3/s (81000 m3/h) and 20.833 m3/s (75000 m3/h). Inlet air has temperature 291.65 K (18.5 °C). It is supplied downward by twisted jets. There are 65 Trox VDL-AHLD-E3/800/0/0/0/RAL 9010 air diffusers with a diameter of 800 mm. The proposed scheme is single-zonal using 24 diffusers PES-D-8-10/15-0,9 4 m above the floor and air removal from the upper zone. This scheme allows halving the air exchange to the minimum outdoor air without recirculation. The air temperature should be decreased by 3.3 K to 288.35 K (15.2 °С). The number of air-conditioners is decreased twice. The calculated consumption of cold decreased by 65.58 W/m2 or 29 %, the calculated consumption of heat for the second heating – by 7.17 W/m2 or 18 %. Saving of capital investments in prices of February 2020 is 792.16 UAH/m2 or 55 %, and decrease of operating costs for the cooling period is 6.61 UAH/m2 or 15 %. Thus, the system is economically beneficial from the beginning of its installation. In the future, its operation will be simulated in a mode with a variable flow rate.
On the calibration dependencies designing for concrete strength testing by sclerometric nondestructive metods
Authors: Snezhkov D. 
Published: May 2021

Sclerometric methods of testing concrete, in particular, the rebound hammer testing, retain their positions as the most common indirect methods for concrete strength determining in situ. They are used as a means for technological testing during the buildings construction, as well as during their inspection during maintenance. Indirect parameters of current sclerometric devices are usually point-values: the rebound index, the diameter and depth of the print, the duration of the indenter insertion process, and the maximum interaction force. However, the lack of an unambiguous relationship between these parameters and the strength of concrete leads to additional uncertainty of the test result, which is one of the problems of sclerometric methods of concrete control. The instability of the calibration dependencies of the method is also observed. Even strict compliance with the requirements of the procedure does not guarantee the repeatability of the obtained dependencies.The article considers the possibility of improving metrological indicators of calibration dependencies of sclerometric methods by introducing an additional parameter-concrete humidity. The possibility of combining two sclerometric methods – the elastic rebound method and the shock pulse method is also considered. Data were obtained on concrete samples with a curing time of 25..60 days. Two-parameter calibration dependencies, including concrete humidity as an additional parameter, allowed for all experimental series of samples to reduce the residual mean square deviation of the calibration dependence of elastic rebound and shock pulse methods by 10%..16%, and to consistently provide the minimum acceptable value of the correlation coefficient r = 0.7 for the studied concrete compositions. The influence of concrete heterogeneity on the readings of sclerometric test methods is considered.The developed method of constructing two-parameter calibration dependencies can be recommended for inclusion in the current standards governing the determination of the strength of concrete structures under construction.
ALSTONIA MACROPHYLLA (APOCYNACEAE): A NEW RECORD OF NATURALIZED SPECIES IN JAVA, INDONESIA
Authors: Effendi Surianto , Achmmad Mustaqim Wendy 
Published: May 2021

Surianto Effendi & Wendy A. Mustaqim. 2021. Alstonia macrophylla (Apocynaceae): A New Record of Naturalized Species in Java, Indonesia. Floribunda 6(6): 207–212. — Alstonia macrophylla (Apocynaceae), a Malesian widespread species tree, here for the first time is formally reported to be naturally found in Java. The report is based on plants growing in the Ciampea limestone hills, Ciampea sub-district, west of Bogor, West Java. Description, ecology, illustration and a brief discussion regarding the occurrence state of this species as naturalized species in Java are presented. A key to Alstonia species in Java is also given.
Analysis of Flue Gas Emission from Gas-fired Wall-mounted Boilers
Authors: Shao Baigui 
Published: May 2021

With the continuous promotion of the coal-to-gas policy in major towns in Beijing and its counties, Hebei, Shandong, and some provinces in Northwestern China, the proportion of household heating in the winter heating market has increased year by year. As one of the main heating equipment, the sales of wall-mounted gas boilers are also increasing year by year. Due to the concentration of installations in cities, the NOx and CO emissions generated by the operation of a huge number of gas-fired wall-mounted boilers gradually appear to have an impact on the environment. This article will measure NOx and CO in the emissions of common gas wall-mounted boilers on the market (including conventional atmospheric gas wall-mounted boilers, low-NOx wall-mounted boilers, secondary condensation low-NOx wall-mounted boilers and fully premixed gas wall-mounted boilers). Through the quantitative analysis and comparison of the data, a reference is given to the selection of the gas wall-mounted boiler.
Leopoldo Zea y el existencialismo mexicano
Authors: Cuéllar Moreno José Manuel 
Published: May 2021

El artículo de 1940 de Leopoldo Zea, “El sentido de responsabilidad en la filosofía actual”, es un punto de arranque para el “existencialismo mexicano”. Zea acuñó su idea de una “nueva filosofía” y de un “nuevo filósofo” en éste y otros artículos de juventud. La “nueva filosofía” debía ser auténtica, circunstancial, histórica, pragmática, salvífica, y debía tener como datos principales la libertad individual del ser humano y la inseguridad radical que conlleva esta libertad. Esta concepción de la filosofía fue posteriormente adoptada por el Grupo Hiperión y enriquecida con sus lecturas del existencialismo francés. El principal objetivo de este trabajo es analizar la concepción de Zea de una “nueva filosofía”.
Palabras clave: Leopoldo Zea, filosofía mexicana, existencialismo mexicano, libertad, Grupo Hiperión.
The Influence of Lesson Study Strategy on Teachers’s Pedagogical Quality in All State Madrasah Aliyah of Medan
Authors: Prasetia Indra , Akrim Akrim , Sulhati Sulhati , Burhanuddin Burhanuddin 
Published: May 2021

The purpose of this study were : (1) to learn pedagogical strategies teachers who follow the guidance of teacher with lesson study and coaching strategies with MGMP convensional teacher, (2) to determine the interaction between teacher coaching strategies with lesson study and strategies with teacher guidance MGMP conventional and subjects the teachers’ pedagogic competence, (3) to find pedagogical english teacher who followed a strategy with teacher guidance conventional MGMP, (4) to learn pedagogical math teacher who followed a strategy of coaching teachers with pedagogical lesson study and mathematics teachers who follow the strategy with teacher guidance conventional MGMP. This study is quasi-experimental research. The number of samples were 60 teachers. The tecnique of determining the sample is done by random sampling. Research hypptheses were tested using Anova 2 ways used before Anova first tested the data analysis requirements of the test for normality of data using Lillieofors test, and homogeneity of variance using the test Bartlet.
An Analysis of Students’ Learning Independence in Learning English for Computer Using Google Classroom
Authors: Dharmawati Dharmawati 
Published: May 2021

This research aims to know independent learning of English for Compute in using Google Classroom during the COVID-19 pandemic. The method used of this research was elaborating from quantitative and qualitative descriptive. The population was Informatics students in the first semester at Universitas Harapan Medan. Sampling techniques used random sampling with a research sample of 65 students of 1-1 and 1-2 classes. Data collection techniques used triangulation: questionnaires, interviews and observations. The results showed that the average level of student learning independence using google classroom in learning English for Computer during COVID-19 pandemic was very high at the average value of indicators: self-confidence (82.62), sel-discipline (85.51), initiative (82.34), responsibility (84.92), motivation (86.27), then the average indicator of independent learning is 84.33. From these results knows that the scale range of the criteria for the score of the respondent's level of achievement, then the interpretation of learning independence in learning English for computer for Informatics students using Google Classroom during the Covid 19 pandemic is very high.
Haemato-biochemical profile during different stages of lactation in local Sahiwal crossbred dairy cows at Savar area of Dhaka district of Bangladesh
Authors: Hasan Sajibul , Miah Mohammad Alam , Islam Md Kamrul 
Published: May 2021

The present study was carried out to investigate the haemato-biochemical profile during different stages of lactation in local Sahiwal crossbreed dairy cows at Savar area of Dhaka district of Bangladesh. Twenty four local Sahiwal crossbreed cows were selected randomly from different small farms and divided into three groups: early stage lactation (1-3 months), mid stage lactation (4-6 months) and late stage lactation (7-9 months). Blood samples were collected during three stages of lactation. There were no statistical significant (p<0.05) variations observed in hematological parameters amongst the three stage of lactation. Although the packed cell volume (PCV), hemoglobin (Hb) concentration and RBC count were found lowest in early stage of lactation than the other groups. Total leucocyte count (TLC), platelet count (PLT), mean corpuscular volume (MCV) and mean corpuscular haemoglobin (MCH) were recorded within normal limits. Similarly, biochemical parameters were observed statistically non-significant amongst the groups studied. The glucose level was recorded lowest in early stage of lactation; whereas, the protein and creatinine concentrations were slightly higher in this stage. Aspartate aminotransferase (AST), Alanine aminotransferase (ALT) and Alkaline phosphatase (ALP) were not varied amongst the three groups of cows. Data generated during the current study may be useful as reference values for the scientific community.
Asian J. Med. Biol. Res. March 2021, 7(1): 1-5