bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interculturality at a US university: International faculty’s experiences with intercultural communication
Authors: Stojanović Maja , Robinson Petra Alaine 
Published: July 2021

Purpose
This paper aims to present the experiences, beliefs and perceptions of international faculty at a Research 1 institution in the Southern US regarding the perceived differences between their and their students’ and colleagues’ cultures and first languages.

Design/methodology/approach
Face-to-face interviews were conducted with four international faculty from Europe and Asia who held appointments at a Research 1 institution in the Southern US. The interviews focused on the participants’ communication experiences with students and colleagues from diverse cultural backgrounds.

Findings
The findings have implications for academic and professional development and support as they show that understanding cultural aspects of language and communication can be challenging for individuals who may not be aware of possible cultural differences.

Originality/value
This study is unique because it presents stories of faculty from different backgrounds, who were born on different continents and who learned English at different ages but are all working in a linguistically homogeneous context. Also, the originality of the study comes from examining the intercultural communication between the participating faculty and their students, as well as their colleagues.
E-textbook technology: Are instructors using it and what is the impact on student learning?
Authors: Roberts Kim , Benson Angela , Mills Jamie 
Published: July 2021

PurposeToday’s digital and mobile learning environment has contributed to the increased availability of and interest in e-textbooks, and many school systems are conducting trials to evaluate their effectiveness. The purpose of this paper is to identify and analyze instructors’ levels of use (LoU) of e-textbook features and innovations at a southeastern US community college. This study also evaluated the effectiveness of e-textbooks compared to paper textbooks on student achievement during a pilot period of e-textbook implementation.Design/methodology/approachUsing a survey research design, the LoU of the Innovation framework was applied to identify and analyze instructors’ LoU rankings for eight e-textbook features. The study also used historical data on student demographics and final course grades to evaluate student achievement between text formats. Descriptive and inferential statistics were used to answer the research questions.FindingsResults showed that e-textbook features were used at a low to non-existent level by instructors and that there was no significant difference in grade average between text formats among students. However, interactions between text format, age and gender were found.Originality/valueThis study added to the body of knowledge regarding e-textbook efficacy. While many studies stop with the conclusion that there is no difference in student outcomes between text formats, this study addressed a gap in literature on how to improve student performance with e-textbook technology by using the LoU of an innovation framework.
Effects of three-step magnesium doping in p-GaN layer on the properties of InGaN-based light-emitting diode
Authors: Hamzah Nur Atiqah , Ahmad Mohd Anas , Mohd Asri Rahil Izzati , Alias Ezzah Azimah , Md Sahar Mohd Ann Amirul Zulffiqal , Sha Shiong Ng , Hassan Zainuriah 
Published: July 2021

Purpose
The purpose of this paper is to enhance the efficiency of the LED by introducing three-step magnesium (Mg) doping profile. Attention was paid to the effects of the Mg doping concentration of the first p-GaN layer (i.e. layer close to the active region). Attention was paid to the effects of the Mg doping concentration of the first p-GaN layer (i.e. layer close to the active region).

Design/methodology/approach
Indium gallium nitride (InGaN)–based light-emitting diode (LED) was grown on a 4-inch c-plane patterned sapphire substrate using metal organic chemical vapor deposition. The Cp2Mg flow rates for the second and third p-GaN layers were set at 50 sccm and 325 sccm, respectively. For the first p-GaN layer, the Cp2Mg flow rate varied from 150 sccm to 300 sccm to achieve different Mg dopant concentrations.

Findings
The full width at half maximum (FWHM) for the GaN (102) plane increases with increasing Cp2Mg flow rate. FWHM for the sample with 150, 250 and 300 sccm Cp2Mg flow rates was 233 arcsec, 236 arcsec and 245 arcsec, respectively. This result indicates that the edge and mixed dislocations in the p-GaN layer were increased with increasing Cp2Mg flow rate. Atomic force microscopy (AFM) results reveal that the sample grown with 300 sccm exhibits the highest surface roughness, followed by 150 sccm and 250 sccm. The surface roughness of these samples is 2.40 nm, 2.12 nm and 2.08 nm, respectively. Simultaneously, the photoluminescence (PL) spectrum of the 250 sccm sample shows the highest band edge intensity over the yellow band ratio compared to that of other samples. The light output power measurements found that the sample with 250 sccm exhibits high output power because of sufficient hole injection toward the active region.

Originality/value
Through this study, the three steps of the Mg profile on the p-GaN layer were proposed to show high-efficiency InGaN-based LED. The optimal Mg concentration was studied on the first p-GaN layer (i.e. layer close to active region) to improve the LED performance by varying the Cp2Mg flow rate. This finding was in line with the result of PL and AFM results when the samples with 250 sccm have the highest Mg acceptor and good surface quality of the p-GaN layer. It can be deduced that the first p-GaN layer doping has a significant effect on the crystalline quality, surface roughness and light emission properties of the LED epi structure.
Does negative information in MD&A can reduce stock crash risk?
Authors: Liu Jianmei 
Published: July 2021

Purpose
As an important part of the disclosure of listed companies' annual reports, MD&A will disclose some "bad news" about the company. The purpose of this paper is to study whether such "bad news" can reduce information asymmetry and alleviate the risk of stock price crash remains to be seen.

Design/methodology/approach
Based on the sample of A-share listed companies from 2007 to 2016, the authors examine whether the negative information in MD&A could reduce stock price crash risk.

Findings
It is found that the negative information in MD&A does not reduce future crash, which indicates that the negative information in MD&A does not alleviate the information asymmetry. Further, it is also found this is due to the low readability of negative information which leads to the negative information not successfully released into the market timely. Only highly readable negative information can alleviate information asymmetry and suppress crash risk. In addition, the authors also find in the companies with more investor surveys negative tone is negatively correlated with crash risk, which means that investor surveys could help investors interpret the negative information in MD&A and alleviate stock price crash risk.

Practical implications
The practical significance of this article: this paper suggests that investors should carefully identify the quality of negative information in MD&A and pay attention to other quality characteristics besides credibility. This paper suggests that the regulator should pay attention not only to whether to disclose and the amount of disclosure but also to the quality of information disclosure, such as readability, so as to restrict management's strategic behavior in information disclosure.

Originality/value
First, different from previous studies on the impact of information disclosure on crash risk, this paper directly explores the impact of information in MD&A on stock price crash risk from the perspective of negative information disclosure that management most want to hide. It supplements the literature on the impact of information disclosure on stock price crash risk. Second, this paper studies the interaction between information tone and readability and its impact on the risk of stock price crash. Some studies believe that the credibility of negative news is higher and investors' reaction may be stronger. However, this paper finds that the disclosure of negative information may not be absorbed by the market because of the low readability. Third, this paper finds that investor surveys can help information users to interpret negative information and alleviate the risk of stock price crash, which shows that information disclosure of different channels will complement each other and improve information efficiency. Therefore, it advocates different information disclosure channels which has important practical significance for improving market pricing efficiency and reducing investment decision-making risk.
Suzhou industrial park and its role in the belt and road initiative: the great stone industrial park in Belarus
Authors: Haro Sly María José 
Published: July 2021

PurposeIn recent years, the People's Republic of China has made remarkable progress in science and technology. The Chinese industry is competing for leadership in cutting-edge technologies such as 5G, robotics, artificial intelligence, aerospace and green energy. This article aims to analyze: What role do industrial parks, especially Suzhou Industrial Park, play in upgrading technology to encourage independent innovation and economic development? How SIP is related to the Belt and Road Initiative?Design/methodology/approachThis research summarizes China's most important scientific and technological reforms and policies and in particular the Torch Program. In addition, it develops a case study of the Suzhou Industrial Park (SIP) by analyzing documents, bibliography and presenting data. It ends with a case study of the role of SIP in the Belt and Road Initiative analyzing the Great Stone Park in Belarus.FindingsThis article highlights that: China's experience clearly shows that the "visible hand" of the State plays a very important role in economic development and technological catch-up. All of them are implemented from a strategy linking the national objectives with the local ones, this is done from a top-down perspective. As an important aspect of economic and social development, China's experience in promoting indigenous innovation in science and technology provides a relevant example for developing countries.Research limitations/implicationsThere are few academic literature on Great Stone Industrial Park.Practical implicationsThe international cooperation of the SIP with the technology parks throughout the BRI-countries provides relevant information to deepen collaboration in this field and could contribute to closing the technological gap in developing countries.Originality/valueThe role of the SIP in the Belt and Road initiative is an under research topic. There is few bibliography discussing the impacts of the cooperation in science and technology in the framework of the BRI.
Examining antecedents and consequences of perceived service quality in the hotel industry: a comparison between London and New York
Authors: Palazzo Maria , Foroudi Pantea , Ferri Maria Antonella 
Published: July 2021

Purpose This paper aims at exploring the relations amongst the concepts of customer relationship management (CRM), convenience, trust, perceived service quality, satisfaction, perceived value, loyalty, image and purchase intention in the hotel sector.Design/methodology/approach The research was conducted using interviews with hospitality managers and guests who had a direct connection with the hotel industry. According to the qualitative study results and literature review, the authors designed a model that was examined via structural equation modelling and fuzzy set qualitative comparative analysis.Findings This paper presents a conceptual framework that enhances existing research in the field of study, as it was implemented to measure the antecedent and consequences of perceived service quality. Based on the results from New York and London, the authors found that CRM and convenience have significant impact on perceived service quality. Interestingly, the aggregated data illustrate the negative relationship between image, loyalty and purchase intention.Originality/value The approach used by this study is partially in line with previous theoretical analyses and shows appealing patterns in international service quality perception. Besides, the paper adds insights into the realm, linking together different dimensions in order to reach an in-depth understanding and complex analysis of each item that affects and is affected by perceived service quality in the hotel industry.
The catalytic activity of mycelial fungi towards 7‐oxo‐DHEA – an endogenous derivative of steroidal hormone dehydroepiandrosterone
Authors: Łyczko Paulina , Panek Anna , Ceremuga Ireneusz , Świzdor Alina 
Published: July 2021

SummarySeventeen species of fungi belonging to thirteen genera were screened for the ability to carry out the transformation of 7‐oxo‐DHEA (7‐oxo‐dehydroepiandrosterone). Some strains expressed new patterns of catalytic activity towards the substrate, namely 16β‐hydroxylation (Laetiporus sulphureus AM498), Baeyer–Villiger oxidation of ketone in D‐ring to lactone (Fusicoccum amygdali AM258) and esterification of the 3β‐hydroxy group (Spicaria divaricata AM423). The majority of examined strains were able to reduce the 17‐oxo group of the substrate to form 3β,17β‐dihydroxy‐androst‐5‐en‐7‐one. The highest activity was reached with Armillaria mellea AM296 and Ascosphaera apis AM496 for which complete conversion of the starting material was achieved, and the resulting 17β‐alcohol was the sole reaction product. Two strains of tested fungi were also capable of stereospecific reduction of the conjugated 7‐keto group leading to 7β‐hydroxy‐DHEA (Inonotus radiatus AM70) or a mixture of 3β,7α,17β‐trihydroxy‐androst‐5‐ene and 3β,7β,17β‐trihydroxy‐androst‐5‐ene (Piptoporus betulinus AM39). The structures of new metabolites were confirmed by MS and NMR analysis. They were also examined for their cholinesterase inhibitory activity in an enzymatic‐based assay in vitro test.
Risk factors associated with complex inferior vena cava filter retrievals and complications: A 7‐year retrieval database analysis and the impact on retrieval rates at an Australian tertiary centre
Authors: Loh Brendon , Liong Rebecca , Malacova Eva , Bain Roger 
Published: July 2021

AbstractIntroductionVenous thromboembolism (VTE) affects approximately 17,000 Australians annually. While anticoagulation is the mainstay of treatment, inferior vena cava filters (IVCFs) are used in patients where this is contraindicated. The primary aim was to identify risk factors for complex retrievals and IVCF‐related complications following the establishment of a database at a single tertiary centre. The secondary aim was to evaluate the IVCF retrieval rate and patients lost to follow‐up.MethodsA retrospective study at a single tertiary centre was conducted on IVCFs inserted from 2012 to 2018. Logistic regression models were used to evaluate potential risk factors for filter‐related complications and complex retrievals.ResultsIn total, 402 patients had an IVCF inserted. Of these, 308 patients (77%) had a retrieval attempted, 10 (3%) of which required more than one retrieval attempt (complex retrieval). Factors associated with filter‐related complications included dwell time (OR 1.02, 95% CI: 1.01–1.04) and select indications for insertion, namely VTE requiring thrombolysis/thrombectomy (OR 2.29, 95% CI: 1.02–5.16) and iliocaval/free‐floating iliofemoral DVT without thrombectomy/thrombolysis (OR 5.89, 95% CI: 1.53–22.71). After mutual adjustment for all variables, only dwell time remained a significant factor for filter‐related complications (adjusted OR 1.03, 95% CI: 1.01–1.05) and complex retrieval (AOR 1.05, 95% CI: 1.02–1.08). The annual retrieval rate increased from 73% (2012) to 83% (2018), with an overall retrieval rate of 75%.ConclusionDwell time is a potential risk factor for filter‐related complications and complex retrievals. The annual IVCF retrieval rate was 75% since an Interventional Radiology‐led database was established.
Systematic review of sirolimus in dermatological conditions
Authors: Swarbrick Andrew W , Frederiks Aaron J , Foster Rachael S 
Published: July 2021

AbstractSirolimus is a mammalian target of rapamycin inhibitor (mTORI) with anti‐proliferative, antiangiogenic and immunosuppressive properties. While approved in Australia as an anti‐rejection medication for renal transplant patients, there is mounting evidence regarding the utility of oral and topical sirolimus in treating a plethora of dermatological conditions or conditions with cutaneous manifestations. Our aim was to present an overview of the evidence for current usage and breadth of the application of sirolimus in dermatology. We carried out a systematic review of all the literature published up to 31 August 2019 on oral and topical sirolimus with respect to dermatological conditions or conditions otherwise relevant to dermatology. While 3368 papers were initially produced in our search, 238 papers met our inclusion criteria and were examined in our review. The conditions examined were categorised into genodermatoses (9 conditions), infection (1 condition), inflammatory/autoimmune (10 conditions), neoplasm (3 conditions) and vascular (17 conditions). We extracted data on first author, publication year, journal, characteristics of the study and study patients, condition, drug modalities, drug efficacy, side effects, blood level of mTORI, co‐interventions and follow‐up. While there is level 1 evidence for the efficacy of sirolimus in conditions such as tuberous sclerosis complex (TSC) and GVHD prophylaxis, for many other conditions, the evidence is limited to level 4 evidence. Regarding oral systemic therapy, dosing regimens varied with the most common for children 0.8mg/m2 twice daily and for adults 1 mg twice daily. Doses were often adjusted to reach a typical trough level of between 5 and 15 ng/mL, though targets often varied. In the overall majority of cases, side effects were minimal or tolerable, including mucositis, cytopenias, lipid abnormalities and nausea/vomiting, and only a few cases had to stop due to adverse effects. Regarding topical therapy, concentration of formulations varied from 0.1% to 1% and were compounded into creams, ointments or gels and administered typically once or twice per day. The most common side effect was skin irritation. There were a number of limitations to our study. In particular, many of the published studies were case reports or case series with no comparator arm, leading to susceptibility of bias in conclusions drawn, in particular a high likelihood of publication bias. Given the heterogeneity amongst studies, comparisons or aggregation of results was difficult. There continues to be growing use of oral and topical sirolimus in dermatological conditions. It provides new therapeutic options to patients where previous therapies have either failed or are limited due to toxicity. However, further studies are warranted.
Potential inappropriate use of strong opioid analgesics in cancer outpatients during the last year of life in France and associated factors
Authors: Chu Thanh Hang , Rueter Manuela , Palmaro Aurore , Lapeyre‐Mestre Maryse 
Published: July 2021

AimsA better knowledge of opioid prescribing patterns would help to identify areas of potential improvement in cancer pain management. This study aimed to identify potential inappropriate use (PIU) of strong opioid analgesics in cancer outpatients in their last year of life.MethodsA retrospective cohort of cancer patients who died between 2011 and 2014 and were exposed as outpatient to a strong opioid analgesic in the last year of life was identified in the Echantillon Généraliste de Bénéficiaires (a 1/97th random sample of the French general population). Prescribing patterns of strong opioids were analysed and PIU was defined by at least 1 of these criteria: overlapping prescriptions; contraindicated prescriptions; lack of laxatives; potential drug interactions; prescription in patients hospitalized for opioid‐related disorders. Factors associated with PIU were investigated through a multiple logistic regression model.ResultsOne third of the 2236 patients (median age 72 years [interquartile range: 61–82], 44.1% women) presented a PIU (insufficient laxative prescription [19.6% of patients], insufficient background treatment with transmucosal fentanyl [14.8%], overlapping prescriptions [2.6%]). The rate of PIU significantly decreased from 37.6% (2011) to 29.8% (2014). For patients with a duration of opioid use ≥3 months, factors associated with PIU were fentanyl prescription (adjusted odds ratio = 2.36; 95% confidence interval [1.86–3.00]) and previous use of strong opioid (adjusted odds ratio = 1.88; [1.50–2.36]).ConclusionIn France, 1/3 of cancer patients exposed to strong opioids experienced PIU and this proportion tended to decrease over time. There is still room for progress in cancer pain management at the end of life.
Assessment of the safe and efficacious dose of the selective progesterone receptor modulator vilaprisan for the treatment of patients with uterine fibroids by exposure–response modelling and simulation
Authors: Sutter Gabriele , Frei Matthias , Schultze‐Mosgau Marcus‐Hillert , Petersdorf Kathrin , Seitz Christian , Ploeger Bart A. 
Published: July 2021

AimsWe report population pharmacokinetic (popPK) and exposure–response (E–R) analyses for efficacy (induced amenorrhoea [IA]) and safety (unbound oestradiol [E2] concentrations) of the selective progesterone receptor modulator vilaprisan. Results were used to inform the dose for the Phase 3 programme in patients with uterine fibroids.MethodsA popPK model was developed using data from Phase 1 and 2 studies (including ASTEROID 1 and 2). The relationship between vilaprisan exposure (steady‐state AUC) and IA after oral administration of 0.5, 1, 2 or 4 mg/day over 3 months was analysed in ASTEROID 1 using logistic regression and qualified in ASTEROID 2 by comparing simulated and observed probability for IA after 2 mg/day. The exposure–E2 relationship was analysed visually.ResultsVilaprisan clearance was 22.7% lower in obese vs non‐obese patients. The E–R relationship for IA in ASTEROID 1 was steep and consistent with ASTEROID 2, with a maximum probability (Pmax) of 59% (95% CI: 49–68%). The exposure at which 50% of Pmax is obtained was 36.9 μg*h/L (95% CI: 27.7–48.7 μg*h/L). Simulations showed that 36% of the patients will be below 90% of Pmax for IA after 1 mg/day compared to 2% after 2 mg/day. E2 levels tended to decrease with increasing exposure. While E2 levels remained largely within the physiologic follicular phase range, the clinical relevance of this decrease will be evaluated in long‐term studies.ConclusionsA 2 mg/day dose was selected for Phase 3 as E–R analyses show this dose results in a close to maximum probability for IA, without any safety concerns noted.