bluuebunny/crossref_metadata_2025_split huggingface dataset:
Penguatan Pendidikan Karakter pada Masa New Normal Covid-19 melalui Flipped Classroom
Authors: Apriani An-Nisa , Suwandi Intan Kurniasari , Ariyani Yusinta Dwi , Sari Indah Perdana 
Published: October 2021

Penelitian ini bertujuan untuk mendeskripsikan tentang peran flipped classroom dalam penguatan karakter siswa sekolah dasar pada masa new normal Covid-19. Metode yang digunakan dalam penelitian ini yaitu penelitian studi kepustakaan. Data dalam penelitian ini merupakan data sekunder berupa buku-buku ilmiah, jurnal ilmiah, dan laporan penelitian. Teknik analisis data dalam penelitian meliputi tiga tahapan: organize, synthesize, dan identify. Hasil penelitian ini menunjukkan bahwa flipped classroom memiliki relevansi yang kuat dalam penguatan pendidikan karakter siswa pada masa new normal Covid-19. Aktivitas dalam flipped classroom meliputi kegiatan tatap muka dan pembelajaran online yang berfokus pada proses pembelajaran yang berpusat pada siswa. Aktivitas pembelajaran tersebut memberikan kesempatan pada siswa sekolah dasar secara lebih luas untuk mengembangkan nilai-nilai moral yang dimilikinya. Pendekatan ini juga mendukung siswa dalam membangun pengetahuan baru, belajar secara efektif dan efesien, dan memperkuat karakter siswa. Pembelajaran melalui flipped classroom mendukung tercapainya tujuan program Penguatan Pendidikan Karakter (PPK) pada masa new normal Covid-19. Salah satu nilai utama PPK yang dapat meningkat dan berkembang melalui pendekatan flipped classroom yaitu nilai kemandirian. Strengthening Character Education in New Normal Covid-19 Periode through Flipped Classroom This study aims to describe the role of flipped classrooms in strengthening the character of elementary school students during the new normal covid-19 period. The method used in this research is library research. The data in this research is secondary data in the form of scientific books, scientific journals, and research reports. The data analysis technique in this research includes three stages: organize, synthesize, and identify. The results of this study indicate that the flipped classroom has strong relevance in strengthening the character education of students during the new normal Covid-19 period. Activities in the flipped classroom include face-to-face activities and online learning that focus on student-centered learning processes. These learning activities provide opportunities for elementary school students to a wider extent to develop their moral values. This approach also supports students in building new knowledge, learning effectively and efficiently, and strengthening student character. Learning through flipped classrooms supports the achievement of the objectives of the Penguatan Pendidikan Karakter’s program (PPK) during the new normal Covid-19 period. One of the main values of PPK’s program that can improve and develop through the flipped classroom approach is the value of independence.
Google Classroom: The Web-Based Media for Teaching English
Authors: Andewi Widi , Pujiastuti Dwi 
Published: October 2021

This study investigates whether: 1) Google Classroom is more effective than the conventional method for teaching writing; 2) The high creativity students have better writing skills than those who have low creativity, and; 3) Interaction between teaching method and students’ creativity in teaching writing occurs. This quasi-experimental study was conducted at STMIK Pringsewu in the academic year of 2020/2021. The sample of this research was two classes, the namely experimental class taught using Google Classroom, and the control class taught using a conventional method. Each class consisted of 20 students, so the total sample is 40 students. The sample was obtained by using the cluster random sampling technique. Each class was divided into two groups, consisting of ten high creativity students and ten low creativity students. The data of this research were obtained from a writing test to find out students' writing scores. Then, the data were analyzed by using 2x2 multifactor analysis of variance ANOVA and Tukey test. The results show that the mean scores of A1B1 are 82.40, A2B1 is 75.30, A1B2 is 68.70, and A2B2 is 69.70. This study implies that Google Classroom is an effective method in teaching writing and is suitable to be implemented to those having high creativity. Google Classroom: Media Berbasis Web untuk Mengajar Bahasa Inggris Penelitian ini menyelidiki apakah: 1) Google Classroom lebih efektif daripada metode konvensional dalam mengajar menulis; 2) Siswa yang kreativitasnya tinggi memiliki kemampuan menulis yang lebih baik dibandingkan siswa yang kreativitasnya rendah; dan 3) Terjadi interaksi antara metode pengajaran dan kreativitas siswa dalam pembelajaran menulis. Penelitian kuasi eksperimen ini dilakukan di STMIK Pringsewu pada tahun pelajaran 2020/2021. Sampel penelitian ini memiliki dua kelas yaitu kelas eksperimen yang diajar menggunakan Google Classroom dan kelas kontrol yang diajar dengan metode konvensional. Setiap kelas terdiri dari 20 siswa, sehingga jumlah sampel adalah 40 siswa. Sampel diperoleh dengan menggunakan teknik cluster random sampling. Setiap kelas dibagi menjadi dua kelompok yang masing-masing terdiri dari 10 siswa kreativitas tinggi dan 10 siswa kreativitas rendah. Data penelitian ini diperoleh dari tes menulis untuk mengetahui nilai menulis siswa. Kemudian data dianalisis dengan menggunakan analisis multifaktor varians 2x2 dan uji Tukey. Hasil penelitian menunjukkan bahwa nilai rata-rata A1B1 adalah 82,40, A2B1 adalah 75,30, A1B2 adalah 68,70, dan A2B2 adalah 69,70. Hasil penelitian ini mengimplikasikan bahwa Google Classroom merupakan metode yang efektif dalam pengajaran menulis dan cocok untuk diterapkan bagi mereka yang memiliki kreativitas tinggi.
Los hongos en la salud y la enfermedad II. Dermatomicosis y dermatofitosis comunes
Authors: Cruz Choappa Rodrigo , Ocara Miranda , Carvallo Javier , Vieille Peggy 
Published: October 2021

En este apunte se describen los principales agentes de dermatomicosis y dermatofitosis, los síntomas y signos, la forma de realizar el diagnóstico y tratamiento. Se actualiza sobre el reordenamiento taxonómico propuesto para los dermatofitos, donde se abandonó la clsificación de tres géneros por una de nueve. También se revisan las infecciones más frecuentes provocadas por levaduras del género Candida y Malassezia.
Development and Characterization of Acetazolamide Nanoemulsion for Effective Ocular Delivery
Authors: Neha Joshi  , Vijay Juyal  , Rajeshwar K.K. Arya  , Himanshu Joshi  
Published: October 2021

Nanoemulsion has the potential of releasing the drug continuously, and they may easily permeate via the intense layers of the eye structure due to nano-size droplets, which makes nanoemulsion an effective drug delivery system for ocular delivery. The objective of our work was to prepare a nanoemulsion of acetazolamide for glaucoma treatment with enhanced efficacy as well as for continuous effect. Based on different compositions of oil (Olive Oil), surfactants (Tween-20), and co- surfactants (Transcutol P), forty-five test mixtures were made, water titration technique was employed for preparing the pseudo-ternary-phase diagrams. On the basis of these phase diagrams, twenty-five acetazolamide loaded nanoemulsion were formulated and examined for their nanosized droplets, PDI, zeta potential, viscosity, pH, transmittance and in-vitro drug release. The formulated nanoemulsion showed all the properties within the desired range i.e., droplet size (15.6 to 21.18), zeta potential (-15.5 to- 24.71), PDI (0.140 to 0.361), viscosity (3.234 ± 0.063to 5.174 ± 0.023cps), pH (6.922 ± 0.026to 7.033 ± 0.012), RI (1.379 ± 0.007 to 1.404 ± 0.006) and % transmittance was found (94.96± 0.6% to 96.68± 0.6%) and also the release rate of acetazolamide from nanoemulsion was found very good i.e., 81.59± 1.04% to 92.46± 0.33% after 24 hrs. The top four formulations having good drug release were selected for further evaluation of droplet sizes and which also fall in the nano range (15.68 to 21.18 nm). The study showed that it is possible to develop nanoemulsion of phenytoin drug, and the in-vitro drug release study showed that the prepared nanoemulsion had good bioavailability, sustained release and ability to target eye as an effective ocular delivery system.
Molecular Docking Studies to Evaluate Small Molecule Inhibitors of Wnt/Betacatenin Signaling Pathway
Authors: Dantu Sai Shyama Lakshmi Sankari  , Sai Sailaja Maka  , Swetha Dalal  , Chandrasekhar Chanda  , Ranganadha Reddy Aluru  
Published: October 2021

Canonical Wnt pathway or β catenin dependent pathway is one of the highly conserved signalling pathway which can control gene expression and regulate cell proliferation, cell adhesion, cell migration, cell polarity and organogenesis. Abnormal regulation of β catenin in the canonical wnt signalling pathway leads to transcription of several genes involved in oncogenic programs. Aberrant signalling of the canonical wnt pathway was observed in several types of cancers including hepatocarcinoma, colorectal cancer and lung cancer. Many small molecules were observed to have the potential to block the aberrant wnt signalling pathway by allosteric binding and inhibiting β catenin molecule. The current study involves screening for ligands which can have strong allosteric binds to β catenin and inhibit wnt signalling pathway. Molecular docking studies were used to evaluate the binding capacity of the selected ligands. Curcumin, Cardamonin, FH535 and ICRT-3 were used as ligands for the molecular docking study with β catenin binding Transcription factor -4 receptor. All chosen ligands have exhibited significant binding energies with the receptor. The highest -9.518272 kcal/mol with Cardamonin followed by -9.28359 kcal/mol with FH535, -8.422604 kcal/mol with curcumin and the least -8.407231 kcal/mol with ICRT-3. All the ligands showed at least 1 hydrogen bond with the target receptor whereas Cardamonin showed 3 hydrogen bonds. Curcumin is a close second forming 2 hydrogen bonds while FH535 and ICRT-3 form only 1 hydrogen bond. The 2D interactions of the ligand and the molecule are visualised by using chimera. We observed Cardamonin to have a very strong binding affinity with the target receptor. Cardamonin can be a suitable drug candidate and might have the potential to inhibit the β catenin dependent wnt signalling pathway.
Screening and Characterization of Biofilm Formation by Staphylococcus Spp and Pseudomonas Spp Isolates from Diabetic Foot Ulcer
Authors: Ramasamy Venkatesan  , Suresh S S Raja  , Vijayakumar.R  , Panneer Selvam.K  
Published: October 2021

Diabetes mellitus is a very serious systemic disease worldwide. Around 416 million cases were estimated in 2015 worldwide, and are expected to reach 549 million in 2030 which is 8.6% higher. Diabetes mellitus is the leading cause of mortality and morbidity and is responsible for 3.8 million deaths annually. 25% of the diabetic patients are affected with foot infections out of which, 15% people are forced for limb amputation which affects the quality of life of the patients. Diabetic foot ulcer is a poly microbial infection mostly occurs due to Staphylococcus spp and Pseudomonas spp and pose serious complications. Bacteria are the cause for much type of diseases and generate resistance to wide range of biofilm forming. Biofilms constitute reservoirs of pathogens and are associated with resistance to antimicrobial agents and chronic infection. The study included 156 patients (59% male and 41% female) suffering diabetic foot ulcer whose pus culture was isolated. The identification of isolates for both gram-negative and gram-positive organisms was done as per the procedures mentioned in Bergey’s manual of Determinative Bacteriology. Further, MALDI- TOF (Matrix-Assisted Laser Desorption/Ionization) was used to confirm the identification of the isolates using classical methods. Staphylococcus spp (65%) and Pseudomonas spp (35%) biofilm producing isolates were identified for Congo red method assay and Tissue culture plate method. Results of biofilm production in positive, intermediate, negative differentiation on the Congo red plate assay and Tissue culture plate method assays were analyzed.
Comparison of Cosmetics Regulations in India and Singapore: A Regulatory Overview
Authors: Kavitha N  , Balamuralidhara V  , Meghana M  
Published: October 2021

Cosmetics are the fastest-growing market potential in the world and have a higher interest rate for women than men. Beauty and personal care products have often been used to enhance beauty, appearance and perfection. A blend of synthetic and herbal cosmetics thrives in India's cosmetics sector. A cosmetic product should be a complete package with all outstanding properties, such as adequate safety, efficacy, potency and marketability of the product. These characteristics are only possible with a good regulatory structure, scheme, and organisation in place. Cosmetic products are continuously revised and managed. which is the task of many regulators. The cosmetics industry has grown exponentially across the world, offering a means for a consumer to transform his or her look and make the product easily recognisable and appealing. The protection of cosmetic products is governed by various regulatory authorities around the world, each with their own set of rules and regulations that the product must follow. There are many regulatory bodies doing work efficiently. These bodies provide us with strict regulations which help us in guiding Manufacturing, Importing, Packaging, Labelling and other aspects of trade in the cosmetic industry. Cosmetic description, manufacturing specifications, licences, import regulations, labelling regulations, packaging regulations, and fee details are mentioned and also the legal authority in India (CDSCO) and Singapore (HSA) are addressed in this context and approval process of import of cosmetics has been discussed in this article. There are drugs and cosmetics legislation (D&C) in India and the Bureau of the Indian Standard (BIS), for Singapore Health products (ASEAN Cosmetic Directive) regulations 2007 under HEALTH PRODUCT ACT are discussed.
Investigation of the Influence of Snow Track Density on Tire Tread Block Traction by Experiments and Discrete Element Method Simulation
Authors: Hindemith Michael , Heidelberger Jonas , Wangenheim Matthias 
Published: October 2021

ABSTRACTWhile in nature, snow properties change from day to day or even minute by minute, one of the great advantages of lab tests is the stability and reproducibility of testing conditions. In our labs at the Institute of Dynamics and Vibration Research, Leibniz Universität Hannover, we currently run three test rigs that are able to conduct tests with tire tread blocks on snow and ice tracks: High-Speed Linear Tester (HiLiTe), Portable Friction Tester (PFT), and Reproducible Tread Block Mechanics in Lab (RepTiL). In the past years, we have run a project on the influence of snow track properties on friction and traction test results with those test rigs. In this article, we will present a first excerpt of the results concentrating on the RepTiL test rig. Because this rig reproduces the movement of rolling tire tread blocks, we executed a test campaign with special samples for the analysis of snow friction mechanics. We evaluated penetration into the snow, maximum longitudinal force level, and longitudinal force gradient. On the other hand, we varied the snow density while preparing our tracks to assess the influence of the snow track density on the friction mechanics. In parallel, we have accompanied our experiments with discrete element method simulations to better visualize and understand the physics behind the interaction between snow and samples. The simulation shows the distribution of induced stress within the snow tracks and resulting movement of snow particles. Hypotheses for the explanation of the friction behavior in the experiments were confirmed. Both tests and simulations showed, with good agreement, a strong influence of snow density and sample geometry.
MODEL PEMBELAJARAN LEMPAR TANGKAP SOFTBALL MENGGUNAKAN MEDIA PEMBELAJARAN PADA SEKOLAH MENENGAH ATAS
Authors: Saputro Agung Kuntoro , Susilo Susilo 
Published: October 2021

Penelitian ini menghasilkan model pembelajaran lempar tangkap softball menggunakan media pembelajaran pada Sekolah Menengah Atas (SMA). Penelitian ini termasuk penelitian pengembangan, dan prosedur pengembangan produk ini terdiri analisis produk yang ingin dibuat, membuat produk awal, uji validasi ahli dan revisi, uji kelompok kecil revisi, uji kelompok besar dan produk akhir. Pengumpulan data dilakukan menggunakan kuesioner yang didapat dari evaluasi ahli, serta menggunakan hasil pengamatan di lapangan yang diperoleh dari siswa, dan penerapan produk. Teknik mengolah data adalah deskriptif persentase. Data yang didapatkan adalah sebelum pemberian perlakuan (kelompok control) berupa model pembelajaran keterampilan lempar tangkap softball diketahui hasil rata-ratanya adalah 21.4 dan hasil rata-rata dari kelompok eksperimen 32.033. Maka terdapat selisih antara kelompok control dan kelompok eksperimen sebanyak 10.633. Maka model pembelajaran keterampilan lempar tangkap softball menggunakan media pembelajaran efektif dalam meningkatkan keterampilan lempar tangkap softball pada SMA. Hasil data dapat disimpulkan bahwa: (1) Model pembelajaran keterampilan lempar tangkap softball menggunakan media pembelajaran pada SMA dapat dikembangkan dan diterapkan dalam pembelajaran maupun saat ekstrakurikuler di sekolah, (2) dari model diperoleh bukti adanya peningkatan dengan ditunjukan hasil pengujian data hasil pretes dan posttest adanya perbedaan yang signifikan antara sebelum dan sesudah adanya perlakuan model
PENGARUH MODEL PEMBELAJARAN DAN MINAT BELAJAR TERHADAP HASIL BELAJAR SENAM LANTAI
Authors: Setiawati Kadek Sri , Parwata I Gusti Lanang Agung , Suratmin Suratmin 
Published: October 2021

Penelitian ini bertujuan untuk membuktikan pengaruh model pembelajaran dan minat belajar terhadap hasil belajar senam lantai. Jenis penelitian ini adalah penelitian true experiment dengan rancangan “treatment by level” dengan dua ketegori 2x2. Sampel penelitian berjumlah 48 orang dipilih berdasarkan kategori minat belajar tinggi dan minat belajar rendah. Data dianalisis menggunakan analisis deskriptif dan analisis varian (ANAVA) dua jalur dengan taraf signifikansi 0,05. Hasil penelitian menunjukkan: 1) Terdapat perbedaan pengaruh hasil belajar senam lantai pada siswa yang mengikuti pembelajaran kooperatif jigsaw dan siswa yang mengikuti model pembelajaran konvensional dengan 9,092 > 2,014, 2) Terdapat interaksi antara model pembelajaran dan minat belajar terhadap hasil belajar senam lantai dengan 164,229 > 2,014, 3) Terdapat perbedaan pengaruh hasil belajar senam lantai (jigsaw dan konvensional) dengan kelompok siswa yang memiliki minat belajar tinggi yang nilai signifikansi differentnya = 9,141 > 2,063 dan 4) Terdapat perbedaan pengaruh hasil belajar senam lantai (jigsaw dan konvensional) dengan kelompok siswa yang memiliki minat belajar rendah yang nilai signifikansi = 4,949 > 2,063.Simpulan dari penelitian ini: : 1) hasil belajar senam lantai pada siswa yang mengikuti pembelajaran kooperatif jigsaw lebih tinggi daripada siswa yang mengikuti model pembelajaran konvensional, 2) Terdapat interaksi antara model pembelajaran dan minat belajar terhadap hasil belajar senam lantai, 3) Untuk siswa yang memiliki minat belajar tinggi, hasil belajar senam lantai siswa yang belajar menggunakan model pembelajaran kooperatif jigsaw lebih tinggi dibandingkan dengan yang menggunakan model pembelajaran konvensional dan 4) Untuk siswa yang memiliki minat belajar rendah, hasil belajar senam lantai menggunakan model pembelajaran konvensional lebih tinggi dibandingkan dengan yang menggunakan model pembelajaran kooperatif jigsaw.
PERMAINAN GERAK DASAR LOKOMOTOR UNTUK ANAK TUNAGRAHITA SEDANG
Authors: Satria M Haris , Wijaya Made Agus 
Published: October 2021

Tujuan dari penelitian ini yaitu untuk mengembangkan permainan gerak dasar lokomotor untuk anak tunagrahita sedang.penelitian ini merupakan penelitian dan pengembangan. Sampel dalam penelitian ini berjumlah 36 orang dari tiga SD SLB C di Kota Palembang. Hasil penelitian menunjukkan bahwa permainan gerak dasar lokomotor untuk anak tunagrahita sedang dapat diaplikasikan akan tetapi dengan intruksi penuh serta pendampingan lebih. Hasil uji efektifitas juga menunjukkan bahwa model ini efektif yang dilihat dari hasil t _ (hitung) = 17.50 > t _ (tabel) = 2,028 sehingga terima Ha dengan Signifikan. Saran dari penelitian ini yaitu para guru/pelatih dapat menggunakan model ini baik dalam pembelajaran maupun latihan akan tetapi dengan pendampingan.
THE INFLUENCE OF COUNTRY OF ORIGIN TOWARDS BRAND EQUITY DIMENSIONS AND PURCHASE INTENTION OF CHINESE SMARTPHONE BRAND
Authors: Sinulingga Edy Kalme Haganta , Jokhu Jean Richard 
Published: October 2021

Penelitian ini bertujuan untuk mengetahui: pengaruh negara asal terhadap dimensi ekuitas merek dan niat beli merek smartphone Cina yaitu Xiaomi. Variabel yang digunakan dalam penelitian ini adalah: negara asal, kesadaran merek, asosiasi merek, loyalitas merek, persepsi kualitas, dan niat beli. Penelitian ini menggunakan metode kuantitatif dengan metode convenience sampling. Pengumpulan data dalam penelitian ini menggunakan data primer dengan menyebarkan kuesioner kepada 302 responden yang pernah menggunakan smartphone chines. Teknik analisis data dalam penelitian ini menggunakan Structural Equation Model (SEM) dengan software SmartPLS 3.0. Berdasarkan analisis yang telah dilakukan, hasil penelitian ini menunjukkan (1) terdapat pengaruh yang signifikan dari negara asal terhadap kesadaran merek, asosiasi merek, loyalitas merek dan persepsi kualitas. (2) Terdapat pengaruh yang signifikan antara kesadaran merek, loyalitas merek, dan persepsi kualitas terhadap niat beli. (3) Tidak terdapat pengaruh yang signifikan antara negara asal dan asosiasi merek terhadap niat beli. This study aimed to find out: the influence of country of origin towards brand equity dimensions and purchase intention of Chinese smartphone brand which is Xiaomi. The variables that used in this study are: country of origin, brand awareness, brand association, brand loyalty, perceived quality, and purchase intention. This study used quantitative methods with convenience sampling method. Data collection in this study used primary data by distributing a questionnaire to 302 respondents who are ever use chines smartphone. The data analysis technique in this study used Structural Equation Model (SEM) with SmartPLS 3.0 software. Based on the analysis that has been done, the result of this study shows (1) there are significant influence of country of origin on brand awareness, brand association, brand loyalty and perceived quality. (2) There are significant influence of brand awareness, brand loyalty, and perceived quality towards purchase intention. (3) There are no significant influence of country of origin and brand association towards purchase intention.