bluuebunny/crossref_metadata_2025_split huggingface dataset:
MANAJEMEN SUPERVISI PENDIDIKAN DALAM PENGEMBANGAN KINERJA GURU PAUD (Studi Kasus di RA Nahdlatussalam Kalimantan Tengah Anjir Serapat)
Authors: Rahimah Rahimah , Majdi Muhammad , Muzdhalifah Muzdhalifah 
Published: November 2021

AbstractThis study aims to find out the management of supervision in auditing institutions in one of the schools in central Kalimantan, namely RA Nahdlatussalam. The study used a qualitative approach with case study, interviews or observations with the principal about management supervision in the RA. From the results of the study, it was found that the supervision of education was carried out once in a month, the supervisor in the implementation of supervision was a person from outside the school. Among those carried out in the implementation of supervision is the supervisor seeing or observing the teachers when learning takes place by assessing according to established assessment guidelines. After completion of the assessment when the learning takes place then the teachers along with the meeting supervisor together discuss about the way the teacher teaches, and so on. If there are deficiencies, the supervisor will provide input and direction to make the teacher better in learning activities. Aside from outside the school who is a supervisor, the principal becomes a supervisor once a month assessing the learning of teachers in the RA. Keyword: Management, Educational Supervison, Early Childhood Education Programs
ANALISIS ONTOLOGI, EPISTEMOLOGI, DAN AKSIOLOGI ILMU PERPUSTAKAAN DAN INFORMASI (Sebuah Kajian Filsafat Ilmu dan Keislaman)
Authors: Juairiah Juairiah 
Published: November 2021

AbstrakIlmu Perpustakaan dan Informasi dalam perspektif Filsafat Ilmu merupakan sebuah disiplin ilmu yang mengkaji proses penggalian Ilmu Perpustakaan dan Informasi bertujuan untuk melihat hakikat dari Ilmu Perpustakaan dan Informasi tersebut. Untuk mencari tahu tentang Filsafat Ilmu Perpustakaan dan Informasi maka dapat digali dari tiga aspek yaitu: Apa yang dikaji oleh pengetahuan Ilmu Perpustakaan dan Informasi itu (ontologi)? Apakah Ilmu Perpustakaan dan Informasi benar-benar dapat disebut ilmu (epistemologi)? Dan untuk apa Ilmu Perpustakaan dan Informasi tersebut (aksiologi)?. Ontologi Ilmu Perpustakaan dan Informasi tidak hanya mengkaji teori-teori ilmu perpustakaan, ilmu terapan yang diterapkan di perpustakaan, dan rekaman informasi; lebih jauh dari itu mempelajari bagaimana cantuman informasi dalam berbagai bentuk media dan sistem temu balik informasinya dalam kaitannya dengan penggunaan teknologi informasi dan komunikasi (ICT). Sedangkan Ilmu Perpustakaan dan Informasi jika dikaji dari segi epistemologi merupakan manajemen pengetahuan manusia, antar cabang ilmu pengetahuan yang paling banyak dibanding dari semua ilmu lain, dan karena menyangkut filsafat ilmu pengetahuan, ilmu ini berpotensi menjadi ilmu yang paling filosofis dibanding ilmu yang dikaji profesi lain. Dan aksiologi dari Ilmu Perpustakaan dan Informasi tentunya sangat urgen dan berguna untuk pencarian dan penyebarluasan informasi bagi kemaslahatan umat manusia, pada pandangan yang lebih luas ilmu ini melalui pustakawan sebagai profeional informasi menjalankan peran perpustakaan sebagai agen perubahan, pembangunan, agen budaya serta pengembangan ilmu pengetahuan dan teknologi dari masa ke masa. Kata Kunci: Filsafat Ilmu, Filsafat Ilmu Perpustakaan dan Informasi, Ontologi,Epistemoogi, Aksiologi
The Effect of Dynamic Electric Puzzle Science Tool-Assisted Inquiry Learning Model Towards Students’ Creative Thinking Skills
Authors: Dewi Eka , Werdhiana I Komang , Saehana Sahrul 
Published: November 2021

The implementation of physics learning still does not involve students' thinking processes. It is very important to practice higher-order thinking skills, one of which is creative thinking. One of the mandated learning models in the 2013 Curriculum is inquiry. This study aimed to analyze the effect of dynamic electric puzzle science tool-assisted inquiry learning on students' creative thinking skills compared to conventional learning. This study used a quasi-experiment research type with a control group pretest-posttest design. This study was done in class XII. The sampling technique was purposive sampling, with XII IPA Al-Qalam as the experimented class and XII IPA Al-Furqan as the controlled class in the academic year of 2020/2021. Data collection was done by creative thinking skills instrument test, which consisted of 5 essay questions. Data were analyzed by using SPSS 25.0 for windows on normality, homogeneity, and N-gain test. Learning outcomes data of both classes were normally distributed and homogenous. Based on the result, the average score of the pretest and posttest of the controlled class were 39.2 and 70.7, while the average scores of the pretest and posttest of the experimented class were 49.0 and 80.2. Data analysis was done by using t test, and it resulted that tcount was 2.439, while ttable was 2.009 or tcount > ttable and the significance was (0.01) < 0.05 meant that there was a significant effect of the inquiry model towards students' creative thinking skills if compared to conventional learning. The improvement of creative thinking skills in experimented class gained <g> score of 0.64, whereas the controlled class gained <g> score of 0.51. Inquiry learning assisted by dynamic electric puzzle science tools can increase students' opportunities to engage in inquiry-based activities and develop students' analytical and creative thinking skills.
Pesan Perdamaian dalam Video Klip Atouna El-Tofoule: Analisis Semiotik Charles Sanders Peirce
Authors: Arin Faridatul Azma  
Published: November 2021

The purpose of this article is to find out the description of peace messages in the Atouna El Toufoule video clip. In the video clip of Atouna El Toufoule, several signs have meaning. The study of meaning in this article uses a qualitative research methodology by analyzing images as data which is analyzed using Charles Sanders Peirce’s semiotics in finding meaning through signs, objects, and interpretants. The results of this study indicate that sign is mostly motivated by social context and does not require excessive interpretation of meaning. The object takes the side of social life that occurs in Palestinian society. Interpretants also sometimes directly criticize social life, culture, and the environment around them. The video clip of Atouna El Toufoule contains a moral message and an invitation to create peace for children living in conflict areas. They need a vacation so they can feel peace and freedom in their lives.
Initiatives to Promote Access to Medicines After the Publication of National Policy on Comprehensive Care of People With Rare Diseases in Brazil
Authors: Cunico Cassia , Vicente Geison , Leite Silvana Nair 
Published: November 2021

Abstract
BackgroundRare diseases affect a small number of people compared to prevalent diseases' estimates. The vast majority of these diseases are of genetic origin, have no cure, are chronic and can lead to death. Although the right to access to medicines is included in the constitutionally guaranteed right to health in Brazil, problems in the supply of medicines for rare diseases are reported in the country. ObjectiveThis study aimed to describe and analyze the initiatives to promote access to medicines for treating rare diseases in Unified Health System, Brazil, after the publication of the National Policy on Comprehensive Care of People with Rare Diseases.MethodsBased on the model published by The WHO Regional Office for Europe, which described access to medicines in pre-launch, per-launch and post-launch policies, the initiatives referring to each category were summarized, based on documentary research searched in online databases, in the period from January 2014 to December 2020. ResultsDifferent actions and policy interventions were identified, which went through the expansion of resources for research and development, health regulations, incorporation of new drugs, review and publication of clinical guidelines, expansion of the network of care facilities by the Ministry of Health. On the other hand, aspects related to care policies, pricing methods, technological development, and development of pharmaceutical services processes were not implemented. ConclusionsAlthough it is impossible to determine the explicit motivation of such actions concerning the Policy, its publication certainly was a landmark in Brazilian society, allowing greater recognition of the needs of rare diseases patients and the treatment's specificities. However, the study suggests that the steps that make up the life cycle of medicines are not linked, lacking articulation and integration of the care network and, consequently, there is no evidence that the rare diseases policy publication has generated broad impact on the promotion of access to medicines to treat rare diseases in Brazil.
Impact of the Paper Degradation State and Constituents on Its Behavior During and After X-ray Exposure
Authors: Gimat Alice , Schoeder Sebastian , Thoury Mathieu , Dupont Anne-Laurence 
Published: November 2021

Abstract
Paper is a complex biopolymer material which contains papermaking additives and often bears inks and other graphic media. Cultural heritage paper-based artefacts are most often deteriorated to some extent. This research explores how intrinsic factors such as constituents and degradation state can impact the modifications incurred in aged papers during and after X-ray examination. To this end laboratory model papers, artificially aged, and 18th and 19th century archival documents, with and without additives (gelatin, calcium carbonate) and iron gallate ink, were exposed to Synchrotron X-ray radiation at doses that were previously shown to incur damage in unaged cotton papers (0.7 to 4 kGy). Glycosidic scissions, hydroxyl free radicals, UV luminescence and yellowing were measured immediately after the irradiation, and were monitored over a period of three years. The depolymerization of cellulose was lower in the aged papers, as well as in the papers containing calcium carbonate and gelatin, than in the unaged fully cellulosic papers. Compared to the papers with no additives, there were more hydroxyl free radicals in the papers with calcium carbonate and slightly less in the gelatin sized papers. UV luminescence and yellowing both appeared post-irradiation, with a delay of several weeks to months, while the intensity of the responses was impacted by the various paper constituents. The papers with iron gallate ink showed limited degradation in the low doses range, most probably due to recombination of the free radicals produced. Doses below 4 kGy did not cause yellowing or UV luminescence of the archival papers within the whole monitoring period. At higher doses (26 to 36 kGy), a slight UV luminescence appeared after 21 months, as well as a slight yellowing after three years, in some of them. No clear correlation between the degradation induced by the irradiation and the constituents in the paper nor its conservation state could be made. The archival papers in good conservation state depolymerized to the same extent as the model papers, while the most degraded archival papers were less impacted than the latter.
Phytochemical Investigation and Evaluation of Anti-Microbial Activities of Some Indigenous Artemisia Spp. of Ethiopia: Rapid Method of Isolation Artemisinin From Artemisia Annua
Authors: Ebu Seid Mohammed , Dekabo Aman , Hailu Tilahun 
Published: November 2021

Abstract
Artemisia spp are one of the most important traditional medicinal plants of Ethiopia which are used for the treatment of infection and non-infection health problems. The genus Artemisia (Astraceae) consists of about 500 species worldwide. Previous reports indicated that the different species of Artemisia have a wide array of biological activities including antimalarial, cytotoxic, antihepatotoxic, antibacterial, antifungal and antioxidant activity. In this study, the main aim was to investigate chemical components of Artemisia spp. (A. abyssinica, A. absinthium and A. annua) and evaluate their antimicrobial activities against bacterial strains. The results indicated that the crude extract of these plants were effective against some selected strains of bacterial strains. Here we isolated the well-known antimalarial drug artemisinin (7 mg, 0.004%) from Artemisia annua leaves using a rapid n-hexane fractionation method. The n-hexane extract of A. abyssinica, ethyl acetate extract of A. absinthium and n-hexane of A. annua showed varying degrees of inhibiting effect against bacterial strains such as Staphylococcus aureus ATCC 25923T, Salmonella enteritidis ATCC13076T, Klebsiella pneumoniae ATCC1053T, boydii ATCC1233T, Escherichia coli ATCC 25922T, hospital acquired Acinetobacter baumannii. The ethyl acetate extract of Artemisia absinthium (A.abe) showed the maximum inhibiting effect (35 mm) against A. baumannii. The minimum zone of inhibition (< 3 mm) was recorded for test extract of A.ap against Klebsiella pneumoniae ATCC1053T. Ethyl acetate extract of Artemisia absinthium (A.abe) was more effective against these selected bacterial strains and the zone of inhibition ranged from 5-35 mm. The minimum inhibition zone (8 mm) was detected against S. typhimurium ATCC 13311T for both A.ac and n-hexane- EtOAc fraction (8:2) of Artemisia abyssinica. The maximum zone of inhibition (25 mm) for fraction (A.ach F4) of Artemisia abyssinica obtained by column chromatography was recorded against S. pyogen ATCC 19615. However, there was no zone of inhibition detected for boydii ATCC1233T due to these test extracts. Significant variations (P = 0.887) were observed between all test extracts of these medicinal plants at 95% of confidence intervals. There is no zone of inhibition or growth for negative control. But, clear zones of inhibition were detected for positive control due to some standard impregnated disks. Based on our results we recommend that various species of Artemisia seem to have great potential for in-depth investigation for various antimicrobial activities that assists the effort in searching for antimicrobial lead compounds.
Sensitivity Analysis of Conformal CCs for Injection Molds: 3D Transient Heat Transfer Analysis
Authors: Silva Hugo Miguel , Noversa João Tiago , Fernandes Leandro , Rodrigues Hugo Luís , Pontes António José 
Published: November 2021

Abstract
Fabricating conformal cooling channels (CCCs) has become easier and more cost-effective because to recent advances in additive manufacturing. CCCs provide better cooling performance in the injection molding process than regular (straight drilled) channels. The main reason for this is that CCCs can follow the molded geometry's paths, but regular machining methods cannot. Thermal stresses and warpage can be reduced by using CCCs, which also improve cycle time and provide a more uniform temperature distribution. Traditional channels, on the other hand, have a more involved design technique than CCC. Computer-aided engineering (CAE) simulations are essential for establishing an effective and cost-effective design. The sensitivity analysis of design variables is the emphasis of this research, with the goal of establishing a design optimization approach in the future. The ultimate goal is to optimize the location of Cooling Channels (CCs) in order to reduce ejection time and increase temperature uniformity. It can be concluded that the parametrization performed in ANSYS Parametric Design Language (APDL), as well as the design variables used, can be applied in practice and could be relevant in future optimization approaches.
New Triazolothiadiazine Derivative Inhibits Stemness and Induces Cell Death in HCC by Oxidative Stress Dependent JNK Pathway Activation
Authors: Kahraman Deniz Cansen , Guven Ebru Bilget , Aytac Peri S. , Aykut Gamze , Tozkoparan Birsen , Atalay Rengul Cetin 
Published: November 2021

Abstract
Hepatocellular carcinoma (HCC) is a highly heterogeneous cancer, and resistant to both conventional and targeted chemotherapy. (NSAIDs) Recently, nonsteroidal anti-inflammatory drugs (NSAIDs) have been shown to decrease the incidence and mortality of different types of cancers. Here, we investigated the cellular bioactivities of a series of triazolothiadiazine derivatives on HCC, which have been previously reported as potent analgesic/anti-inflammatory compounds. From the initially tested 32 triazolothiadiazine NSAID derivatives, 3 compounds were selected based on their IC50 values for further molecular assays on 9 different HCC cell lines. 7b, which was the most potent compound, induced G2/M phase cell cycle arrest and apoptosis in HCC cells. Cell death was due to oxidative stress-induced JNK protein activation, which involved the dynamic involvement of ASK1, MKK7, and c-Jun proteins. Moreover, 7b treated nude mice had a significantly decreased tumor volume and prolonged disease-free survival. 7b also inhibited the migration of HCC cells and enrichment of liver cancer stem cells (LCSCs) alone or in combination with sorafenib. With its ability to act on both proliferation, stemness and the migration of HCC cells, 7b can be considered for the therapeutics of HCC, which has an increased rate of incidence ~3% annually.
Using the Choquet Integral for the Determination of the Anxiety Degree
Authors: Chiţescu Ion , Manea Mădălina Giurgescu , Paraschiv Titi 
Published: November 2021

Abstract
This paper introduces a mathematical model describing how the EEG type waves are processed in order to characterize the level of anxiety. The electroencephalogram (EEG) is a recording of the electrical activity of the brain. The main frequencies of the human EEG waves are: Delta, Theta, Alpha (Low Alpha and High Alpha), Beta (Low Beta and High Beta), Gamma. Psychologists' studies show that there is an interactive relationship between anxiety and two factors in the Big Five theory, namely, extraversion and neuroticism. The specialists in psychology state that the anxiety is characterized by LowAlpha, HighAlpha, LowBeta and HighBeta waves. In this regard, we developed a mathematical model through which EEG waves are processed in order to determine the level of anxiety. Our main idea is to use the Choquet integral with respect to a suitable monotone measure in order to characterize the level of anxiety. This measure was obtained using the measurements of the values of EEG waves made on 70 subjects and the corresponding levels of anxiety (established by psychologists) of these subjects. In order to verify our mathematical model (aggregation tool) we used it to determine the level of anxiety of 10 other subjects, comparing our results with the results provided by psychologists (the comparison validated our results).
Evaluation of Early Innate and Adaptive Immune Responses to the TB Vaccine Mycobacterium Bovis BCG and Vaccine Candidate BCGdBCG1419c
Authors: Gunasena Manuja , Shukla Rajni Kant , Yao Naiquan , Mejia Oscar Rosas , Powell Michael D , Oestreich Kenneth J , Aceves-Sánchez Michel de Jesús , Valdez Mario Alberto Florez , Liyanage Namal P M , Robinson Richard T 
Published: November 2021

Abstract
The vaccine Mycobacterium bovis Bacillus Calmette–Guérin (BCG) elicits an immune response that is protective against certain forms of tuberculosis (TB); however, because BCG efficacy is limited it is important to identify alternative TB vaccine candidates. Recently, the BCG deletion mutant and vaccine candidate BCGDBCG1419c was demonstrated to survive longer in intravenously infected BALB/c mice due to enhanced biofilm formation, and better protected both BALB/c and C57BL/6 mice against TB-induced lung pathology during chronic stages of infection, relative to BCG controls. BCGDBCG1419c-elicited protection also associated with lower levels of proinflammatory cytokines (i.e. IL6, TNFa) at the site of infection in C57BL/6 mice. Given the distinct immune profiles of BCG- and BCGDBCG1419c-immunized mice during chronic TB, we set out to determine if there are early immunological events which distinguish these two groups, using multi-dimensional flow cytometric analysis of the lungs and other tissues soon after immunization. Our results demonstrate a number of innate and adaptive response differences between BCG- and BCGDBCG1419c-immunized mice which are consistent with the latter being longer lasting and potentially less inflammatory, including lower frequencies of exhausted CD4+ T helper (TH) cells and higher frequencies of IL10-producing T cells, respectively. These studies suggest the use of BCGDBCG1419c may be advantageous as an alternative TB vaccine candidate.
Factors Affecting the Purchase of Commercial Health Insurance: Based on Personal Health Status and the Substitution Effect of Social Insurance
Authors: Yu Wenguang , Wang Qi , Guan Guofeng , Huang Yujuan 
Published: November 2021

Abstract
Background: How health status affects residents’ purchase of commercial health insurance and whether social insurance will crowd out the demand of commercial health insurance are important issues related to the development of commercial health insurance. Further, this paper also attempts to answer why people with worse health buy less commercial health insurance through mechanism analysis. Methods: We used Logit model to analyze the impact of self-rated health level on the purchase of commercial health insurance and the crowding out effect of participating in social health insurance on the purchase of commercial health insurance. In addition, we also successively introduced the respondents with worse and worse health status for regression analysis and analyzed the reasons why the poor health groups reduce the purchase of commercial medical insurance. Results: When performing regression analysis on whether to purchase commercial health insurance, the regression coefficient of having social health insurance is -0.497 and the regression coefficient of self-rated health level is -0.182, but the health status has no significant impact on whether to have social health insurance. Conclusions: The expansion of social basic health insurance has a restraining effect on the promotion of commercial health insurance, and self-rated health level has a negative impact on the purchase of commercial health insurance. The reason why individuals with poor health buy less commercial health insurance is that commercial insurance companies often refuse to cover individuals in poor health.JEL: I11, G22
Optical Modelling of GaAs/GaSb Core-Shell Cone Topped Octagonal Faced Nanopillar Array with Periodic Trapezoidal Textured Cut for High Photon Trapping Efficiency
Authors: Baruah Smriti , Borah Janmoni , Bora Joyatri , Maity Santanu 
Published: November 2021

Abstract
Proficiency in light reflectance mitigation is the most crucial factor for high photodetector performance. In this respect light trapping mechanism based on nanostructures or microstructures such as nanopillars, nanocones, nanopyramids have emerged as the most promising candidate for reducing overall light reflectance. This could be attributed to its effective large irradiation area, multiple scattering of incident light as well as increased path length of incident rays in these nanostructures. This paper proposes an optical modelling of a GaAs/GaSb material based vertically oriented core-shell cone topped octagonal shaped nanopillar structure with periodical trapezoidal nanotexturization over it to be deployed over a circular planar detector’s surface of radius 50um. The geometrical analytical investigation of the proposed model exhibits a 0.999 overall absorbance and 0.995A/W photoresponsivity along with 87% EQE at 1um operating wavelength.