bluuebunny/crossref_metadata_2025_split huggingface dataset:
PSXIV-16 Performance, carcass, wholesale, and retail cuts yield of lambs reared under thermal stress in grazing conditions and slaughtered at two body weights
Authors: Rodriguez Abner A , Rivera Aixa , Bayne Alana , Duckett Susan K 
Published: October 2021

Abstract
Lamb production in tropical areas is conducted under heat stress in extensive grazing conditions of naturalized pastures (NP). The average daily gain (ADG) and yields of hot (HCY) and cold (CCY) carcass, wholesale cuts (WSC); neck (N), shoulder (SL), ribs 5–12 (RIB), loin (LN) and leg (LG), and detail cuts (DTC); shoulder chops (SCH), french chops (FCH), ribs (RS), back leg (BL) and shanks (SH) of 12 lambs (X = 19.4 kg) rotationally grazed (3 d occupation and 24 d resting period) for 154 or 238 d were determined. The Lambs grazed &gt;8 h NP, grass hay and water were offered ad libitum, 150 g/d of a supplement (12% CP), and mineral blocks. Weekly weights were used to determine ADG. Lambs were slaughtered at 22 (SW1) or 35 kg (SM2) to determine HCY and CCY, and WSC and DTC yield as % of cold carcass weight. Performance data was analyzed as a randomized experimental (CRD) design over time. Carcass and cut yields data were analyzed as a CRD with 6 replicates per treatment. Lambs fed during 238-d had similar ADG than those fed 154-d (68.14 vs.47.74 g/d). SW1 and SW2 had similar percentages of HCY (35.21 vs. 38.14) and CCY (34.48 vs. 37.40). The WSC as % of cold carcass weight, N (6.43 vs. 7.06), SL (29.95 vs. 30.20), RIB (16.10 vs. 16.95), LN (10.84 vs. 11.33) and LG (36.51 vs. 34.44) were similar for SW1 and SW2. Yield of SCH and SH was lower (P &lt; 0.05) for SW1 (15.80 and 8.11) than SW2 (23.00 and 9.11), but FCH (8.49 vs. 8.57), RS (6.89 vs. 7.00) and BL (36.52 vs 34.45) were similar. In summary, lambs slaughtered at 35 kg improved the retail cut yield, but did not influence ADG, HCY, CCY, and WCY compared to lighter lambs.
Co-evolutionary Signals IdentifyBurkholderia pseudomalleiSurvival Strategies in a Hostile Environment
Authors: Chewapreecha Claire , Pensar Johan , Chattagul Supaksorn , Pesonen Maiju , Sangphukieo Apiwat , Boonklang Phumrapee , Potisap Chotima , Koosakulnirand Sirikamon , Feil Edward J , Dunachie Susanna , Chantratita Narisara , Limmathurotsakul Direk , Peacock Sharon J , Day Nick P J , Parkhill Julian , Thomson Nicholas R , Sermswan Rasana W , Corander Jukka 
Published: October 2021

AbstractThe soil bacterium Burkholderia pseudomallei is the causative agent of melioidosis and a significant cause of human morbidity and mortality in many tropical and subtropical countries. The species notoriously survives harsh environmental conditions but the genetic architecture for these adaptations remains unclear. Here we employed a powerful combination of genome-wide epistasis and co-selection studies (2,011 genomes), condition-wide transcriptome analyses (82 diverse conditions), and a gene knockout assay to uncover signals of “co-selection”—that is a combination of genetic markers that have been repeatedly selected together through B. pseudomallei evolution. These enabled us to identify 13,061 mutation pairs under co-selection in distinct genes and noncoding RNA. Genes under co-selection displayed marked expression correlation when B. pseudomallei was subjected to physical stress conditions, highlighting the conditions as one of the major evolutionary driving forces for this bacterium. We identified a putative adhesin (BPSL1661) as a hub of co-selection signals, experimentally confirmed a BPSL1661 role under nutrient deprivation, and explored the functional basis of co-selection gene network surrounding BPSL1661 in facilitating the bacterial survival under nutrient depletion. Our findings suggest that nutrient-limited conditions have been the common selection pressure acting on this species, and allelic variation of BPSL1661 may have promoted B. pseudomallei survival during harsh environmental conditions by facilitating bacterial adherence to different surfaces, cells, or living hosts.
The Interwar Period
Authors: Hawthorne Melanie 
Published: October 2021

Abstract
The upheavals of World War I wrought many changes affecting the way decadence played out over the next two decades. Yet an assessment of some of the main sites of interwar decadence reveals much continuity: it remained an urban phenomenon, but while some cities (such as Paris) continued to dominate, new sites of decadence also emerged (Weimar Berlin, Los Angeles). Gender relations underwent a radical shift but remained a privileged theme, while the new visibility of dissident sexualities (homosexuality, transsexuality) offered new terrain. Culturally, these themes were expressed in traditional literary forms such as the novel, but new forms also emerged, most notably film. Regardless of genre, however, the debts to nineteenth-century decadence are evident throughout. In terms of politics, decadence led directly to fascism in some places, while in others it was the fascists who denounced “degeneracy,” but either way, the period ended with another cataclysmic war.
TMS measures explored by EEG recordings
Authors: Ilmoniemi Risto J. , Rogasch Nigel C. , Casarotto Silvia 
Published: October 2021

Abstract
This chapter describes the use of electroencephalography (EEG) to measure neuronal activity evoked by transcranial magnetic stimulation (TMS). We discuss the major research and clinical applications of TMS–EEG and review synthetic measures designed to assess the functional status of cortical networks, such as neuronal excitability and effective connectivity. We first highlight that brain reactivity to TMS crucially depends on the anatomical and functional characteristics of the cortical region being stimulated. These findings suggest that the responses to stimulation of the primary motor cortex should be considered a special rather than a representative case of the brain’s reaction to TMS. Next, we describe TMS–EEG-based measures of (i) cortical reactivity in the time and frequency domains, (ii) excitation and inhibition provided by paired-pulse paradigms, and (iii) neuroplasticity induced by non-invasive neuromodulatory interventions. Finally, we discuss the methodological challenges related to concurrent TMS–EEG and review methods for minimizing/suppressing artifacts that may contaminate brain signals. We conclude that TMS–EEG has great potential for becoming an effective research and clinical tool, provided that: 1) data quality is monitored in real time; 2) effective and sound artifact-removal methods are developed and implemented; and 3) sufficient control studies are performed to assess the impact of TMS on the cortex.
Legal Uses of Anthropology in France in the Nineteenth and Twentieth Centuries
Authors: Audren Frédéric , Guerlain Laetitia 
Published: October 2021

AbstractThis chapter sheds light on the long-standing history of the relationship between law and the human and social sciences in nineteenth- and twentieth-century France. This story has often been reduced to its most recent and academic development, that is, legal anthropology. However, focusing on this strictly contemporary, academic definition of anthropology risks overlooking the many and varied ways of thinking that, over the past two centuries and more, have shaped the relationship between law and the study of humanity. The authors suggest that such an approach obscures the depth and the variety of forms that this relationship took over time. This chapter documents the various ways that legal scholars in France—over the course of two centuries marked by the rise of codification and legal positivism—drew upon history, philology, ethnology, physical anthropology, and sociology, all in the pursuit of a more profound understanding of homo juridicus.
Paul as a Character in Early Christian Narratives
Authors: Snyder Julia 
Published: October 2021

AbstractThe apostle Paul is featured as a character in a wide variety of early Christian narratives. This chapter considers first how Paul is portrayed in a number of different story-style narratives, including the Acts of the Apostles, the Acts of Thecla, the Ephesus Act, and two different accounts of Paul’s martyrdom. Attention is drawn to the creative energy storytellers poured into telling tales about the famous apostle. The chapter argues that many storytellers seem to have felt free to shape their stories according to their own ingenuity and interests, rather than being preoccupied with producing ‘historically accurate’ accounts. It also highlights a range of factors that may have influenced how Paul is portrayed in any given narrative, including plot concerns, pre-existing traditions about other characters with whom Paul shares the stage, and recourse to stock motifs and story templates. In addition to this exploration of story-style narratives, the chapter examines how Paul functions as an authoritative voice in two narratives of slightly different genres, a fictional letter exchange known as 3 Corinthians or the Corinthian Correspondence, and a tour of the afterlife known as the Apocalypse of Paul.
Lateral Thoracic Artery Can Stabilize Circulation in the Pectoralis Major Myocutaneous Pedicle Flap: Single-center, Prospective, Uncontrolled Case Series
Authors: Kumegawa Shinji , Miyazaki Hidetaka , Sakata Yasuhiro , Uemura Kazuhisa , Ueno Kazuki , Wada Yoshitaka , Hyuga Taiju , Asamura Shinichi 
Published: October 2021

Background:
Head and neck reconstructions using the pectoralis major myocutaneous pedicle flap (PMMF) with thoracoacromial artery alone are prone to hemodynamic instability, possibly leading to infection, prolapse, hematoma, seroma, and partial or total flap failure (6%–71%). Aside from unstable blood circulation, reported risk factors for these complications include feminine gender, smoking, and having diabetes mellitus. Preservation of the lateral thoracic artery in addition to the thoracoacromial artery has been suggested as a way to improve unstable blood circulation in the PMMF.

Methods:
This is a single-center, prospective, uncontrolled case series. Circulation to the PMMF was studied intraoperatively with and without lateral thoracic artery clamping after harvest. Indocyanine green (ICG) angiopathy, a quantitative hemodynamic assessment method, was used to analyze three parameters: maximum intensity (Imax), time from start of ICG to maximum intensity (Tmax), and slope of intensity (Smax = Imax/Tmax). Hemodynamic parameters, such as pulse rate and blood pressure, were all within normal ranges. Allergy to contrast media was criterion for exclusion.

Results:
Six patients all had oral cancer as their primary disease. Their background was characterized by established risk factors: four patients had a history of smoking, two had diabetes mellitus, and two were women. Postoperatively, no patients had complications at the recipient or donor sites. Mean results of the analysis were Imax: 60 ± 47, Tmax: 91 ± 55, Smax: 0.8 ± 0.5 in the clamped group and Imax: 85 ± 40, Tmax: 73 ± 42, Smax: 1.8 ± 1.5 in the un-clamped group. Significant difference was observed in Imax (P = 0.03) and Smax (P = 0.03).

Conclusion:
Lateral thoracic artery preservation appears to be useful for stabilizing blood circulation to the PMMF, including in patients considered to be at high-risk for complications, such as women, smokers, and patients with diabetes mellitus.
Newly Identified Gross Human Anatomy: Eight Paired Vestigial Breast Mounds Run along the Embryological Mammary Ridges in Lean Adults
Authors: Teplica David , Kovich Grant , Srock Jamey , Whitaker Robert , Jeffers Eileen , Wagstaff David A. 
Published: October 2021

Background:
Although isolated accessory breasts have been reported in many locations on the torso, we noted that lean men presenting for liposuction had mounds of fullness in a curvilinear array (axilla to groin) consistent with the configuration of the embryological mammary ridge. We hypothesized that grid mapping and pinch testing would elucidate the pattern of fullness and its relation to the “milk line.”

Methods:
Twenty lean participants (10 men, 10 women) each underwent standardized photography and grid mapping of anterior torsos. We then pinch-tested each for subcutaneous fullness in 250 standardized loci. We used plotted pinch values and OLS regression models to determine if focal fullness corresponded to published configurations of the embryologic mammary ridge.

Results:
We identified a pattern of paired mounds in all participants running bilaterally in curved linear arrays from axillae to groin in the exact form of milk lines. Regression models applied to the male and female pinch data indicated that focal thickness matched mammary ridge configurations in all subjects (P = 0.023 for men, <0.001 for women). Fatty fullness never appeared elsewhere on the anterior torsos.

Conclusions:
The linear pattern of paired focal fat mounds present on the anterior torsos is consistent with the paths of embryological mammary ridges, suggesting these focal fat pads are of breast origin. The consistent mounds are distinct from general subcutaneous fullness and therefore represent a new finding of gross human anatomy. We recommend further research to define differential physiology of distinct subpopulations of yellow fat and clinical implications.
Use of Ultra-high-frequency Ultrasound for Aplasia Cutis Congenita of the Scalp
Authors: Karakawa Ryo , Yano Tomoyuki , Yoshimatsu Hidehiko , Koto Mayu , Nakao Atsushi , Ichi Shunsuke 
Published: October 2021

Summary:
Aplasia Cutis Congenita (ACC) in the scalp is a rare congenital malformation. The treatment for ACC with large defects involving the scalp, bone, and the dura is challenging. Local debridement of necrotic tissue is important to prevent lethal complications such as infection and meningitis. However, debridement has the risk of damaging the sagittal sinus or the dura. Recent developments in ultra-high-frequency ultrasound(US) systems provide frequencies of 70 MHz and capability resolution as fine as 30 μm, which could allow precise imaging of small and thin anatomical structures. The study aimed to describe the methods of precise evaluation of the defect in the scalp and safe debridement using ultra-high-frequency US. This is the first report on direct observation of a newborn’s brain using ultra-high-frequency US. The boy was delivered spontaneously with a large defect of the scalp and bone. After 14 days, due to signs of infection, local debridement was performed carefully under ultra-high-frequency US-based evaluation. The dura, the sagittal sinus, and the small anatomical structures such as arachnoid granulations could be observed. Because the brain herniation gradually aggravated, dural reconstruction using fascia lata and scalp reconstruction using transposition flap was performed. Finally, good skin coverage over the defects was obtained. This method minimizes the risk of damaging the sagittal sinus and the brain parenchyma, which may cause fatal complications. Although further clinical investigations will be required to confirm its efficacy, ultra-high-frequency US has the potential to be a useful device for ACC treatment.
Patient-reported Outcomes Among Vulnerable Populations in the Medicare Bundled Payments for Care Improvement Initiative
Authors: McClellan Sean R. , Trombley Matthew J. , Maughan Brandon C. , Kahvecioglu Daver C. , Marshall Jaclyn , Marrufo Grecia M. , Kummet Colleen , Hassol Andrea 
Published: October 2021

Background:
The Centers for Medicare & Medicaid Services Bundled Payments for Care Improvement (BPCI) initiative tested whether episode-based payment models could reduce Medicare payments without harming quality. Among patients with vulnerabilities, BPCI appeared to effectively reduce payments while maintaining the quality of care. However, these findings could overlook potential adverse patient-reported outcomes in this population.

Research Design:
We surveyed beneficiaries with 4 characteristics (Medicare-Medicaid dual eligibility; dementia; recent institutional care; or racial/ethnic minority) treated at BPCI-participating or comparison hospitals for congestive heart failure, sepsis, pneumonia, or major joint replacement of the lower extremity. We estimated risk-adjusted differences in patient-reported outcomes between BPCI and comparison respondents, stratified by clinical episode and vulnerable characteristic.

Measures:
Patient care experiences during episodes of care and patient-reported functional outcomes assessed roughly 90 days after hospitalization.

Results:
We observed no differences in self-reported functional improvement between BPCI and comparison respondents with vulnerable characteristics. Patient-reported care experience was similar between BPCI and comparison respondents in 11 of 15 subgroups of clinical episode and vulnerability. BPCI respondents with congestive heart failure, sepsis, and pneumonia were less likely to indicate positive care experiences than comparison respondents for at least 1 subgroup with vulnerabilities.

Conclusions:
As implemented by hospitals, BPCI Model 2 was not associated with adverse effects on patient-reported functional status among beneficiaries who may be vulnerable to reductions in care. Hospitals participating in heart failure, sepsis or pneumonia bundled payment episodes should focus on patient care experience while implementing changes in care delivery.
Revising Recruitment for Focus Groups to Meet Shifting Needs During COVID-19
Authors: Parker Pearman D. , McSweeney Jean C. , Hadden Kristie B. , Hess Kaycee G. 
Published: October 2021

Background
The COVID-19 pandemic forced researchers to modify recruitment strategies to meet accrual goals for qualitative studies. Traditional methods of in-person recruiting and using paper marketing material were eliminated almost overnight at the onset of the pandemic. Researchers quickly adapted their recruitment strategies, but researchers had to shift local, in-person recruitment efforts to solely using online platforms. The shifting recruitment strategies were accompanied with unexpected challenges, but we were able to meet our accrual goal for focus groups.

Objectives
The objective of this brief report is to explore new recruitment strategies that developed during the COVID-19 pandemic and offer suggestions for future online-based qualitative studies.

Results
Prior to COVID-19, we designed four main strategies (research registry, marketing material, social media, and provider endorsement) to recruit potential participants for focus groups as part of a qualitative, descriptive study involving young women breast cancer survivors. After the onset of COVID-19, we successfully adapted each of our initial four strategies to recruit potential participants in an incremental process. Using these adapted strategies, a total of 62 young women completed the first part of the data collection process prior to participating in a focus group. Thirty-three women participated in the focus groups, and the remaining 29 participants were lost to follow-up. The vast majority of participants were recruited through marketing material and social media after making strategic changes to recruitment.

Discussion
The most effective method of recruitment was the strategic use of marketing material and social media, and we offer suggestions for researchers considering online recruitment methods. We recommend that researchers use various social media platforms and specific hashtags and target their sample population at the onset of the study. The data collection changes initiated by the effects of COVID-19 may remain, and researchers can consider implementing permanent recruitment strategies to best meet the needs of this new landscape of conducing online focus groups.
Single Intraosseous Simvastatin Application Induces Endothelial Progenitor Cell Mobilization and Therapeutic Angiogenesis in a Diabetic Hindlimb Ischemia Rat Model
Authors: Zhu Junxiong , Tan Jie , Zhang Chenggui , Jia Jialin , Leng Huijie , Xu Yingsheng , Song ChunLi 
Published: October 2021

Background:
Endothelial progenitor cells have shown the ability to enhance neovascularization. In this study, the authors tested whether intraosseous delivery of simvastatin could mobilize endothelial progenitor cells and enhance recovery in a hindlimb ischemia model.

Methods:
There are eight groups of rats in this study: normal control; type 1 diabetes mellitus control group control without drug intervention; and type 1 diabetes mellitus rats that randomly received intraosseous simvastatin (0, 0.5, or 1 mg) or oral simvastatin administration (0, 20, or 400 mg). All type 1 diabetes mellitus rats had induced hindlimb ischemia. The number of endothelial progenitor cells in peripheral blood, and serum markers, were detected. The recovery of blood flow at 21 days after treatment was used as the main outcome.

Results:
The authors demonstrated that endothelial progenitor cell mobilization was increased in the simvastatin 0.5- and 1-mg groups compared with the type 1 diabetes mellitus control and simvastatin 0-mg groups at 1, 2, and 3 weeks. Serum vascular endothelial growth factor levels were significantly increased at 2 weeks in the simvastatin 0.5- and 1-mg groups, in addition to the increase of the blood flow and the gastrocnemius weight at 3 weeks. Similar increase can also been seen in simvastatin 400 mg orally but not in simvastatin 20 mg orally.

Conclusion:
These findings demonstrate that a single intraosseous administration of simvastatin mobilized endothelial progenitor cells at a dose one-hundredth of the required daily oral dose in rats, and this potent mobilization of endothelial progenitor cells markedly improved diabetic limb ischemia by means of neovascularization.
Protective Effect of Fat-Tissue–Derived Products against Ultraviolet Irradiation–Induced Photoaging in Mouse Skin
Authors: Zhu Shengqian , Cai Junrong , Wang Jing , Feng Jingwei , Lu Feng 
Published: October 2021

Background:
Exposure to ultraviolet radiation causes erythema, inflammation, and photoaging. Mechanical micronization of adipose tissue can concentrate functional cells and has great potential as an alternative for regenerative medicine. Stromal vascular fraction gel is produced by means of a series of mechanical processes of lipoaspirates and can be injected intradermally. This study aimed to assess the therapeutic effect of stromal vascular fraction gel on photoaging skin.

Methods:
A photoaging model was established in nude mice. Photoaging mice received treatments of stromal vascular fraction gel, fat, tretinoin, or phosphate-buffered saline. Photoaging skin was characterized by histologic and immunohistochemical analyses. Expression of collagen synthesis–related or photoaging-related genes was assessed.

Results:
Stromal vascular fraction gel, fat, and tretinoin reversed photoaging, whereas stromal vascular fraction gel demonstrated the greatest therapeutic effect. Treatment with stromal vascular fraction gel restored intradermal fat tissue content and increased dermal collagen density. Injection of stromal vascular fraction gel had the strongest effect on stimulating fibroblasts and increasing the expression of transforming growth factor β1 (TGF-β1), propeptide of type-I procollagen, and Smad 2, decreasing the expression of Smad 3, compared with fat and tretinoin. Expression of photoaging-related genes was significantly reduced, whereas expression of fibulin-5 was significantly increased after stromal vascular fraction gel treatment.

Conclusions:
Stromal vascular fraction gel demonstrated remarkable therapeutic effects in reversing photoaging skin. Stromal vascular fraction gel can be injected intradermally and survive within dermal layer after grafting. This product increased TGF-β1expression and activated fibroblasts to produce propeptide of type I procollagen, thus increasing the amount of collagen I, leading to thickening of the dermis of photoaging skin.