bluuebunny/crossref_metadata_2025_split huggingface dataset:
End-of-life transitions for family member on the solid tumour oncology ward: the 3 Wishes Project
Authors: Day Gwenyth , Bear Danielle , Swinton Marilyn , Karlin Daniel , Phung Peter , McCann Kelly , Bell Allegra , McParlane Rayna , Granone Maria Carmela , Cook Deborah J , Neville Thanh H 
Published: September 2021

ObjectivesAlthough death is not uncommon for hospitalised patients with cancer, there are few interventions in oncology that are designed to create a dignified, compassionate end-of-life (EOL) experience for patients and families. The 3 Wishes Project (3WP), a programme in which clinicians elicit and implement final wishes for dying patients, has been shown effective in intensive care units (ICUs) at improving the EOL experience. The objective was to initiate 3WP on an oncology ward and evaluate its effect on family member experiences of their loved one’s EOL. We hypothesised that the 3WP can be implemented in the non-ICU setting and help oncological patients and their families with transition to the EOL.MethodsWhen the patient’s probability of dying is greater than 95%, patients and families were invited to participate in the 3WP. Wishes were elicited, implemented and categorised. Audiorecorded, semistructured interviews were conducted with family members, transcribed and analysed using content analysis.Results175 wishes were implemented for 52 patients with cancer (average cost of US$34). The most common wish (66%) was to personalise the environment. Qualitative analysis of 11 family member interviews revealed that the 3WP facilitates three transitions at the EOL: (1) the transition from multiple admissions to the final admission, (2) the transition of a predominantly caregiver role to a family member role and (3) the transition from a focus on the present to a focus on legacy.ConclusionThe 3WP can be implemented on the oncology ward and enhance the EOL experience for hospitalised patients with cancer.
The Complexity of Promise SAT on Non-Boolean Domains
Authors: Brandts Alex , Wrochna Marcin , Živný Stanislav 
Published: September 2021

While 3-SAT is NP-hard, 2-SAT is solvable in polynomial time. Austrin et al. [SICOMP’17] proved a result known as “(2+ɛ)-SAT is NP-hard.” They showed that the problem of distinguishing
k
-CNF formulas that are
g
-satisfiable (i.e., some assignment satisfies at least
g
literals in every clause) from those that are not even 1-satisfiable is NP-hard if
g/k
< 1/2 and is in P otherwise. We study a generalisation of SAT on arbitrary finite domains, with clauses that are disjunctions of unary constraints, and establish analogous behaviour. Thus, we give a dichotomy for a natural fragment of
promise constraint satisfaction problems
(
PCSPs
) on arbitrary finite domains.

The hardness side is proved using the algebraic approach via a new general NP-hardness criterion on polymorphisms, which is based on a gap version of the Layered Label Cover problem. We show that previously used criteria are insufficient—the problem hence gives an interesting benchmark of algebraic techniques for proving hardness of approximation in problems such as PCSPs.
Optimization of the Formulation of Rice Biscuits Supplemented with D. Edulis (L.) Powder Using Response Surface Methodology
Authors: Eyenga Eliane Flore , Mouafo Hippolyte Tene , Achu Mercy Bih Loh , Mbacham Wilfred F. , Ndindeng Sali Atanga 
Published: September 2021

Trends in the food industry are nowadays directed towards the reduction of the level of trans fatty acids in food intended for human consumption. The present study was designed and aimed at valorizing Dacryodes edulis (L.) powder as a substitute for margarine in the production of functional rice biscuits. The effect of substituting margarine and refined wheat flour with D. edulis powder locally called safou and rice flour, respectively, at different proportions was assessed for the sensory and physicochemical properties of the formulated biscuits. For this, statistical models were developed, validated, and optimized using the response surface methodology with the Doehlert design as a tool. The results showed that an increase in the substitution rate of margarine with of D. edulis powder enhanced the aroma while the substitution of refined wheat flour with rice flour led to an improvement of the overall quality of the biscuits. The optimal composition of dough for the production of biscuits with satisfying sensory properties was 20.24% of wheat flour, 24.51% of rice flour, 19.09% of margarine, and 2.47% of D. edulis powder. The optimized biscuit which scored the highest overall acceptability contained proteins (10.33 g/100 g DM), fat (27.66 g/100 g DM), crude fibers (2.5 g/100 g DM), ash (3.55 g/100 g DM), and carbohydrates (54.01 g/100 g DM). It has an energy density of

506.3
±
0.1

kcal
/
g

and could therefore be suitable for the management of malnutrition. Mineral analysis revealed that the biscuit contained sodium (0.200 mg/100 g), potassium (0.192 mg/100 g), phosphorus (0.123 mg/100 g), iron (33.60 ppm), and zinc (26.81 ppm) at levels satisfying the recommended daily intakes. The results of this study demonstrated the suitability of safou as substitute of margarine in the rice biscuit formulation and suggests the potential of the formulated biscuits in the management of malnutrition and noncommunicable diseases such as hypertension, obesity, and cardiovascular diseases.
Short‐ and Long‐Term Clinical Outcomes for Patients With Takotsubo Syndrome and Patients With Myocardial Infarction: A Report From the Swedish Coronary Angiography and Angioplasty Registry
Authors: Redfors Björn , Jha Sandeep , Thorleifsson Sigurdur , Jernberg Tomas , Angerås Oskar , Frobert Ole , Petursson Petur , Tornvall Per , Sarno Giovanna , Ekenbäck Christina , Ravn‐Fisher Annika , Y‐Hassan Shams , Lyon Alexander R. , James Stefan , Erlinge David , Omerovic Elmir 
Published: September 2021

Background
Takotsubo syndrome (TS) is a potentially life‐threatening acute cardiac syndrome with a clinical presentation similar to myocardial infarction and for which the natural history, management, and outcome remain incompletely understood. Our aim was to assess the relative short‐term mortality risk of TS, ST‐segment–elevation myocardial infarction (STEMI), and non‐STEMI (NSTEMI) and to identify predictors of in‐hospital complications and poor prognosis in patients with TS.

Methods and Results

This is an observational cohort study based on the data from the SCAAR (Swedish Coronary Angiography and Angioplasty Registry). We included all patients (n=117 720) who underwent coronary angiography in Sweden attributed to TS (N=2898 [2.5%]), STEMI (N=48 493 [41.2%]), or NSTEMI (N=66 329 [56.3%]) between January 2009 and February 2018. We compared patients with TS to those with NSTEMI or STEMI. The primary end point was all‐cause mortality at 30 days. Secondary outcomes were acute heart failure (Killip Class ≥2) and cardiogenic shock (Killip Class 4) at the time of angiography. Patients with TS were more often women compared with patients with STEMI or NSTEMI. TS was associated with unadjusted and adjusted 30‐day mortality risks lower than STEMI (adjusted hazard ratio [adjHR], 0.60; 95% CI, 0.48–0.76;
P
<0.001), but higher than NSTEMI (adjHR, 2.70; 95% CI, 2.14–3.41;
P
<0.001). Compared with STEMI, TS was associated with a similar risk of acute heart failure (adjHR, 1.26; 95% CI, 0.91–1.76;
P
=0.16) but a lower risk of cardiogenic shock (adjHR, 0.55; 95% CI, 0.34–0.89;
P
=0.02). The relative 30‐day mortality risk for TS versus STEMI and NSTEMI was higher for smokers than nonsmokers (adjusted
P
interaction STEMI=0.01 and
P
interaction NSTEMI=0.01).

Conclusions
The 30‐day mortality rate in TS was higher than in NSTEMI but lower than STEMI despite a similar risk of acute heart failure in TS and STEMI. Among patients with TS, smoking was an independent predictor of mortality.
Lower‐Intensity Statins Contributing to Gaps in Care for Patients With Primary Severe Hypercholesterolemia
Authors: Eid Wael E. , Sapp Emma Hatfield , Flerlage Elijah , Nolan Joseph R. 
Published: September 2021

Background
Although severe hypercholesterolemia confers a 5‐fold increased long‐term risk for coronary artery disease, treatment guidelines may not be fully implemented, leading to underdiagnosis and suboptimal treatment. To further understand the clinical features and gaps in treatment approaches, we analyzed electronic medical record data from a midwestern US multidisciplinary healthcare system, between 2009 and 2020.

Methods and Results

We retrospectively assessed the prevalence, clinical presentation, and treatment characteristics of individuals currently treated with statin therapy having a low‐density lipoprotein cholesterol (LDL‐C) value that is either (1) an
actual
maximum electronic medical record–documented LDL‐C ≥190 mg/dL (group 1, n=7542) or (2) an
estimated
pretreatment LDL‐C ≥190 mg/dL (group 2, n=7710). Comorbidities and prescribed lipid‐lowering therapies were assessed. Statistical analyses identified differences among individuals within and between groups. Of records analyzed (n=266 282), 7% met the definition for primary severe hypercholesterolemia. Group 1 had more comorbidities than group 2. More individuals in both groups were treated by primary care providers (49.8%–53.0%, 32.6%–36.4%) than by specialty providers (4.1%–5.5%, 2.1%–3.3%). High‐intensity lipid‐lowering therapy was prescribed less frequently for group 2 than for group 1, but moderate‐intensity statins were prescribed more frequently for group 2 (65%) than for group 1 (52%).

Conclusions

Two percent of patients in our study population being treated with low‐ or moderate‐intensity statins have an
estimated
LDL‐C ≥190 mg/dL (indicating severe hypercholesterolemia), but receive less aggressive treatment than patients with a maximum
measured
LDL‐C ≥190 mg/dL.
Going Local and Global: Internal and Transatlantic Migration in Eighteenth-Century Spain
Authors: Eyal Hillel 
Published: September 2021

Abstract
Evidence from eighteenth-century marriage applications in Mexico City and Cadiz reveals that migration from Spain to the New World was primarily an extension of domestic movements from rural to urban areas, not the direct result of transatlantic networks. The migratory dynamism that pervaded Spanish society fueled Spain’s fledgling urbanization in the era of commercial capitalism, as peasants increasingly moved to towns and cities, especially to Cadiz. Many of these internal migrants subsequently used the social capital and other resources that they had accumulated in Cadiz and elsewhere on the Iberian Peninsula to facilitate migration to the New World.
Occupation, Reparations, and Rebellion: The Soviets and the East German Uprising of 1953
Authors: Geerling Wayne , Magee Gary B. , Smyth Russell 
Published: September 2021

Abstract
Analysis of the link between the Soviet occupation of East Germany and internal resistance within the German Democratic Republic reveals that ongoing payment of reparations by East Germans out of local production—via the Soviet’s ownership of prominent local companies—affected both the incidence and the intensity of unrest at the precinct level during the uprising of June 17, 1953. This result is robust when controlling for variation in the presence of Soviet military bases and deaths in Soviet nkvd Special Camps, as well as a host of regional factors potentially correlated with differences in unrest.
Who Is He Calling WEIRD?
Authors: McCants Anne E. C. 
Published: September 2021

Abstract
In The WEIRDest People in the World, Henrich offers something of a big-think, global, social-science history that covers everything from psychology experiments to anthropological narrative, economic argumentation, and kinship studies, all grounded in a purported history of religious and family law. The book seeks to persuade that the West is cognitively different from the rest of the world and that its uniqueness explains every fundamental aspect of its modern trajectory—its wealth and education distributions, the progress and spread of its innovations, the presence or absence of trust outside its local communities, its formal institutions of democratic governance, and its beliefs about fairness and equality. Even more important for historically oriented readers, the book seeks to uncover how this major cognitive development emerged. The quantitative methods that the book employs to support its sweeping claims, however, are flawed, and its version of European church- and family-law history is inconsistent with the consensus view of specialist historians.
Quality of service and commitment to tobacco dependence treatment for individuals living with mental disorders in France: A pilot study
Authors: Castaldelli-Maia João M , Gonçalves Priscila D , Lima Danielle R , Moura Helena F , Apter Gisèle 
Published: September 2021

Background: There are remarkably high smoking rates in patients living with mental disorders (PLWMD), and the absence of a specific treatment policy for smoking cessation for these patients worldwide. The present study aimed to (i) investigate the quality of service and commitment to tobacco dependence treatment, and (ii) produce high-quality French versions of the Index of Tobacco Treatment Quality (ITTQ) and Tobacco Treatment Commitment Scale (TTCS). Methods: ITTQ and TTCS were used to assess French mental health professionals ( n = 80). Both scales were translated from their original language following standard procedures (i.e. forward translation). Descriptive analysis for total score, each factor and item were calculated for the entire sample, followed by subgroup analysis by gender, and role of the practitioner. Results: Nurses presented higher levels of both treatment commitment and treatment quality in their mental health care units, compared to psychiatrists, and residents. Overall, counseling offering was low and there was a perception that it is unfair to take tobacco away from PLWMD. In the other hand, there were high levels of smoking assessment and perceptions that nicotine dependence should be included in drug treatment programs. Conclusions: There is a gap in tobacco treatment implementation for French PLWMD. The present pilot study alerts about the problem, and should stimulate larger studies validating such measures for wide use with French-speaking mental health professionals. French nurses presented higher levels of both treatment commitment and quality, and could be in a leadership position for such implementation. Encouraging the implementation of tobacco counseling within conventional mental health treatment is critical to improve cessation rates among this population. There is a potential for the sustainability of tobacco treatment interventions since the levels of commitment observed here were higher than in previous studies conducted abroad.
Public libraries’ responses to a global pandemic: Bangladesh perspectives
Authors: Begum Dilara , Roknuzzaman Md , Shobhanee Mahbub E. 
Published: September 2021

The whole world is experiencing a new reality – the global outbreak of COVID-19, which has forced every institution into lockdown. This study aims to explore the responses of the government public libraries of Bangladesh. An online questionnaire was used to gather primary data from all of the 71 public libraries, which was followed by semi-structured interviews with eight librarians. The analysis suggests that more than 50% of the libraries had a low level of preparedness to face any crisis, and none of the libraries were fully prepared to manage this pandemic. All of the libraries were open for administrative functions without physical access to users. The study found that 52% of the libraries created public awareness through social media, while 46% supported local government organizations and 40% provided counselling services. Considering the existing challenges, the study recommends some measures for the public libraries of Bangladesh to cope with this situation.
Return to Sports and Minimum 2-Year Outcomes of Primary Arthroscopic Hip Labral Reconstruction for Irreparable Tears in High-Level Athletes With a Propensity-Matched Benchmarking Against a Labral Repair Control Group
Authors: Jimenez Andrew E. , Monahan Peter F. , Owens Jade S. , Maldonado David R. , Saks Benjamin R. , Ankem Hari K. , Sabetian Payam W. , Lall Ajay C. , Domb Benjamin G. 
Published: September 2021

Background: Labral reconstruction has shown promise for the treatment of irreparable labral tears in high-level athletes. The literature is scarce regarding outcomes and timing of return to sports (RTS) in these patients. Purpose: (1) To report minimum 2-year patient-reported outcome (PRO) scores and RTS characteristics for high-level athletes undergoing primary labral reconstruction for irreparable labral tears and (2) to compare clinical results with a matched control group of athletes undergoing labral repair. Study Design: Cohort study; Level of evidence, 3. Methods: Data were prospectively collected and retrospectively reviewed for high school, college, and professional athletes who underwent a primary arthroscopic labral reconstruction between January 2010 and June 2018. Minimum 2-year PROs were compared for the modified Harris Hip Score (mHHS), Nonarthritic Hip Score (NAHS), and Hip Outcome Score–Sport Specific Subscale (HOS-SSS), as well as the visual analog scale (VAS) pain score, patient satisfaction, and RTS. The percentages of patients achieving the Patient Acceptable Symptom State (PASS) and minimal clinically important difference (MCID) for the mHHS (PASS, >74 points; MCID, >8 points) and HOS-SSS (PASS, >75 points; MCID, >6 points) were also recorded. These patients were propensity score matched in a 1:3 ratio to other high-level athletes undergoing labral repair. Results: A total of 17 high-level athletes with primary arthroscopic labral reconstruction were included with a median follow-up time of 37.1 months (95% CI, 37.2-60.3 months). They demonstrated significant improvement from preoperatively to the latest follow-up for mHHS, NAHS, HOS-SSS, and VAS for pain ( P < .05). Further, patients achieved PASS/MCID for mHHS at high rates (PASS, 84.2%; MCID, 68.4%). Athletes were able to return to sport-specific training at a median of 3.33 months (95% CI, 3.07-4.71 months) and RTS at a median of 6.2 months (95% CI, 5.08-11.98 months). Fourteen (82.4%) of reconstructions and 29 (82.8%) of repairs either returned to sport or decided not to do so for reasons unrelated to the hip. PROs, RTS rate, and PASS/MCID rates were similar between the labral reconstruction group and a control labral repair group ( P > .05). Conclusion: Primary arthroscopic labral reconstruction for irreparable labral tears was associated with significant improvement in PROs and high rates of RTS in high-level athletes. These results were comparable with those of a control group of athletes undergoing labral repair.
Full Code to Do-Not-Resuscitate: Culturally Adapted Palliative Care Consultations and Code Status Change Among Seriously Ill Hispanic Patients
Authors: Patel Neela K. , Passalacqua Stacey A. , Meyer Kylie N. , de Erausquin Gabriel A. 
Published: September 2021

Background: Palliative care and hospice services are disproportionately underutilized by ethnic minority patients. Addressing barriers to utilization of these services is critical to reducing disparities. The purpose of this study was to assess the impact of a culturally adapted palliative care consultation service for Hispanics on end-of-life decisions, specifically likelihood of changing from full code to do-not-resuscitate (DNR) status during index admission for serious illness. Methods: A cross-sectional study design was applied to data extracted from electronic health records (EHR) of patients seen by a Geriatric Palliative Care service during inpatient stays between 2018 and 2019. The majority of referrals came from critical care sites. Culturally adapted palliative care consultations using the SPIKES tool featured a Spanish-speaking team member leading discussions, involvement of multiple and key family members, and a chaplain who is a Catholic Priest. Results: The analytic sample included 351 patients who were, on average, 72 years old. 54.42% were female, 59.54% were Hispanic, and of Hispanic patients, 47.37% spoke primarily Spanish. Culturally adapted consults resulted in higher rates of conversion to DNR status in palliative cases of the target population. Both primary language and ethnicity were associated with likelihood of change from full code to DNR status, such that Spanish speakers and those of Hispanic ethnicity were more likely to switch to DNR than non-Hispanics and English-Speakers. Conclusion: This study illustrates how culturally adapted palliative care consultations can help reduce barriers and improve end-of-life decision-making, and can be applied with similar populations of seriously ill Hispanic patients.
Spiritual Care Assessment and Intervention (SCAI) for Adult Outpatients With Advanced Cancer and Caregivers: A Pilot Trial to Assess Feasibility, Acceptability, and Preliminary Effects
Authors: Perez Shelley E. Varner , Maiko Saneta , Burke Emily S. , Slaven James E. , Johns Shelley A. , Smith Olivia J. , Helft Paul R. , Kozinski Kathryn , Torke Alexia M. 
Published: September 2021

Background: Although religion and spirituality are important to adults with cancer and their family caregivers, few studies have tested spiritual care interventions in the outpatient setting. Aim: To determine the feasibility, acceptability, and preliminary effects of chaplain-delivered, semi-structured spiritual care to adult outpatients with advanced cancer and their caregivers. Design: In this pre/post pilot intervention study, board-certified chaplains utilized the Spiritual Care Assessment and Intervention (SCAI) framework during 4 individual sessions. Surveys at baseline and at 1, 6, and 12 weeks post-intervention assessed spiritual well-being, quality of life, depression, anxiety, and religious coping. Setting/Participants: We enrolled U.S. adult outpatients with or without an eligible family caregiver. Eligible patients were at least 18 years old and at least 2 weeks post-diagnosis of incurable and advanced-stage lung or gastrointestinal (GI) cancer. Results: Of 82 eligible patients, 24 enrolled (29.3%); of 22 eligible caregivers, 18 enrolled (81.8%). Four planned chaplain visits were completed by 87.5% of patients and 77.8% of caregivers. All enrolled participants completed baseline surveys, and more than 75% completed follow-up surveys at 2 of 3 time points. More than 80% of patients and caregivers reported they would recommend the sessions to a friend or family member. Patients’ spiritual well-being improved significantly at all timepoints compared to baseline: 1-week post (p < .006), 6-weeks post (p < .001), and 12-weeks post (p < .004). Conclusions: Spiritual care through SCAI is feasible, acceptable, and shows promise in improving spiritual well-being and other important outcomes in advanced-stage cancer patients and family caregivers. Further investigation is warranted.