bluuebunny/crossref_metadata_2025_split huggingface dataset:
Broadband Electrostatic Waves Behind Dipolarization Front: Observations and Analyses
Authors: Guo Z. Z. , Fu H. S. , Cao J. B. , Yu Y. , Chen Z. Z. , Xu Y. , Liu Y. Y. , Wang Z. , Chen G. , Xiong X. 
Published: December 2021

AbstractUsing high‐resolution MMS data, we report the observations of broadband electrostatic waves associated with parallel electron temperature anisotropy () behind a dipolarization front (DF). These electrostatic waves include electrostatic solitary waves and electron cyclotron waves. To quantify electron anisotropy, we define the parallel flux anisotropy parameter , where is phase space densities at each energy. By performing correlation analyses between parallel flux anisotropies () and power spectral densities (PSDs) of these waves, we find that: (a) in 0.8–20 keV are positively correlated with the parallel electric field fluctuations in 50–3,000 Hz; (b) in 0.8–20 keV are positively correlated with perpendicular electric field fluctuations in all frequency ranges; (c) the correlation between parallel flux anisotropies and perpendicular electric field fluctuations is more significant in this case. We also discuss the possibility of electron firehose instability and wave–particle interactions. Our study promotes the understanding of the properties and dynamics of DFs.
Individualised Homoeopathy in the Treatment of Onycholysis: An Evidence-Based Clinical Case Report
Authors: Debnath Dhiraj , Banerjee Abhiram , Rahaman Md Mostafijur , Choubey Gurudev 
Published: December 2021

Abstract
Introduction Onycholysis is a chronic nail disorder characterised by the progressive separation of the nail plate from the underlying nail bed. Apart from causing pain and discomfort, it affects the quality of life of an individual due to its visualised cosmetic appearance.
Case Summary A 45-year-old female presented with complete loss of nail plate of the left middle finger for 1 month. At the first visit, homoeopathic medicine Tuberculinum bovinum was prescribed and the patient was followed up periodically for 4 months. A series of photographs captured at the first visit and in subsequent visits objectively document the gradual regrowth of her nail plate. Various aspects of her subjective improvement were documented by three validated outcome measurement scales. The patient herself assessed that, after 4 months of follow-up, she is ‘back to normal’ for her main complaint as well as for the overall well-being, which is documented as a +4 score in ‘Outcome in Relation to Impact on Daily Living’ (ORIDL) scale. The Dermatology Life Quality Index (DLQI) score was reduced from 20 at the first visit to 1 after 4 months of treatment. Modified Naranjo Criteria for Homeopathy (MONARCH) score recorded at the final visit (+8 in ‘-6 to +13’ scale) is suggestive of a high likelihood that the improvement in the patient can be attributed to the homoeopathic treatment provided.
Conclusion This clinical case report is presented here to critically document the effect of individualised homoeopathic treatment in onycholysis within a plausible timeframe.
Homeopathic Treatment of Subclinical Hypothyroidism—A Series of 19 Cases
Authors: Grelle Luiz Carlos Esteves , Camacho Luiz Antonio Bastos 
Published: December 2021

Abstract
Background Subclinical hypothyroidism (SCH) is a common clinical problem. Controversy surrounds the definition, clinical importance, and need for prompt diagnosis and treatment of the mild form of SCH.
Aim The aim of the study was to analyze the evolution of serum thyroid stimulating hormone (TSH) levels after a therapeutic homeopathic intervention in women older than 40 years with SCH.
Methods This study is a retrospective series of 19 cases of SCH, with serum TSH levels between 5 and 10 mIU/L, treated exclusively with homeopathic medicines prescribed on an individualized basis.
Results Nineteen patients were included according to the inclusion and exclusion criteria. Their mean age was 56 years, they were followed for a mean duration of 69 months, the mean number of serum TSH level measurements was 18, and the intervention was successful for 13 patients.
Conclusion The homeopathic therapeutic intervention was successful in 68% of the patients, with serum TSH levels back within the normal range (0.5–5.0 mIU/L).
A Randomised Placebo-Controlled Trial to Assess the Efficacy of Osteoarthritic nosode in the Treatment of Knee Osteoarthritis
Authors: Sexena Reteka , Jain Tarkeshwar 
Published: December 2021

Abstract
Background Knee osteoarthritis (OA) is the most common musculoskeletal disease that affects the ability for sitting on the chair, standing, walking and climbing stairs and various other daily living activities of an affected individual.
Objective The primary objective of the study was to assess the efficacy of Osteoarthritic nosode in the treatment of knee OA on the symptomatic and functional domains in comparison to control group with knee-specific exercises as co-intervention in both the groups.
Materials and Methods It was a single blind randomised controlled trial study conducted at the out/inpatient department of Dr Madan Pratap Khunteta Homoeopathic Medical College, Hospital & Research Centre and Dr Girendra Pal Homoeopathic Hospital, Homoeopathy University, Saipura, Sanganer, Jaipur for a period of 1 year where cases were registered for first 9 months so that minimum of 3 months follow-up can be obtained during the course of the study. Total 50 patients who were radiographically diagnosed to be suffering from knee OA excluding Grade 4 of knee OA were allocated equally and randomly into two treatment groups. The patients in Group A received placebo and physiotherapy and patients in Group B received Osteoarthritic nosode and physiotherapy. The changes in patients' symptomatic and functional domain were evaluated by Knee Outcome Survey-Activity of Daily Living Scale (KOS- ADLS) questionnaire score assessed at the baseline and after 3 months (six follow-ups at 15 days interval) of treatment.
Results Out of 50 patients enrolled, 45 patients completed the trial. Those patients who had completed 3 months of follow-up, that is, 6 follow-ups at 15 days interval, were included in the study. The results showed that the patients with knee OA in Group B had significant improvement in both symptomatic and functional domains after treatment when compared with their initial status and when compared with Group A. Group A (placebo and physiotherapy) showed non-significant to no improvement in 72% of cases and 16% were aggravated when assessed on the symptomatic and functional domains. Group B (OA nosode and physiotherapy) showed mild to marked improvement in 80% of cases, whereas 12% showed non-significant to no improvement when assessed on the symptomatic and functional domains.
Conclusion Osteoarthritic nosode with physiotherapy is significantly effective than placebo with physiotherapy in the management of cases of knee OA.
Pyoderma Gangrenosum after Cardiac Surgery
Authors: Petrov Asen , Kappert Utz , Schmidt Torsten , Matschke Klaus Ehrhard , Wilbring Manuel 
Published: December 2021

Abstract
Background Pyoderma gangrenosum after cardiac surgery is a rare, noninfectious ulcerating skin disease mimicking sternal wound infection.
Methods A systematic search of literature for pyoderma gangrenosum complicating cases of cardiac surgery was conducted between September 1985 and September 2020 on PubMed and Cochrane databases. A systematic review and detailed overview of clinical presentation, diagnostic, treatment, and outcome is provided.
Results A total of 15 studies enclosing 15 patients suffering from pyoderma gangrenosum following cardiac surgery were identified. Onset of symptoms was observed after a median of 5 days. Patients were predominantly male (81.3%) with a median age of 64 years. Typical clinical presentation mimicked sternal site infection, mainly by means of mediastinitis. Specific signs were rapid progression, erythematous to violaceous color of the wound border, accompanied by unspecific symptoms including fever, malaise, and severe pain. Additionally, pathergy (development of ulcers at the sites of minor cutaneous trauma) was reported frequently. Biopsy is mandatory with a cutaneous neutrophilic inflammation confirming the diagnosis. Initial treatment mostly (75.0% of reported cases) was misled, addressing suspicion of surgical site infection. After correct diagnosis, the treatment was switched to an immunosuppressive therapy. Full sternal wound closure took between 5 weeks and 5 months. Reported case mortality was 12.5% in actually low-risk surgeries.
Conclusion Despite pyoderma gangrenosum has typical signs, it remains an exclusion diagnosis. The treatment is completely opposite to the main differential diagnosis—the typical surgical site infection. Knowledge about diagnosis and treatment is essential in the context of avoiding fatal mistreatment.
Ejection Fraction Recovery after Coronary Artery Bypass Grafting for Ischemic Cardiomyopathy
Authors: Ntinopoulos Vasileios , Papadopoulos Nestoras , Odavic Dragan , Haeussler Achim , Dzemali Omer 
Published: December 2021

Abstract
Background Controversy exists about left ventricular systolic function recovery after coronary artery bypass grafting in patients with ischemic cardiomyopathy. The aim of this study is to evaluate the temporal evolvement of left ventricular systolic function after coronary artery bypass surgery in patients with ischemic cardiomyopathy.
Patients and Methods A total of 50 patients with coronary artery disease and left ventricular ejection fraction (LVEF) ≤35% underwent isolated coronary artery bypass grafting in a single center in the period 2017 to 2019. We performed a retrospective analysis of the echocardiographic and clinical follow-up data at 3 months and 1 year postoperatively.
Results Median LVEF preoperatively was 25% (20–33%), mean patient age was 66 ± 8.2 years, 33 (66%) patients were operated off-pump, and 22 (44%) procedures were non-elective. There was no in-hospital myocardial infarction, stroke, and repeat revascularization. Three (6%) patients underwent re-exploration for bleeding or tamponade. In-hospital mortality was 8% and 1-year mortality was 12%. At 1 year postoperatively, there was no repeat revascularization, no myocardial infarction, 1 (2.6%) patient had a transient ischemic attack, and 10 (20%) patients required an implantable defibrillator. There was a statistically significant median ejection fraction increase at 3 months (15% [5–22%], p < 0.0001) and 1 year (23% [13–25%], p < 0.0001) postoperatively, with an absolute increase ≥10% in 32 (74.4%) and 30 (78.9%) patients at 3 months and 1 year, respectively.
Conclusion Patients with ischemic cardiomyopathy undergoing coronary artery bypass surgery show continuous recovery of left ventricular systolic function in the first postoperative year.
Comparative Analysis of Abrasive Materials and Polishing System on the Surface Roughness of Heat-Polymerized Acrylic Resins
Authors: Onwubu Stanley Chibuzor , Mdluli Phumlane Selby 
Published: December 2021

Abstract
Objective The aim of this in vitro experiment was to see how the operator's manual skills, polishing equipment, and abrasive materials affected the surface roughness of denture base resins.
Materials and Methods Forty polymethyl methacrylate (PMMA) specimens were created and polished by using two different polishing systems, namely hand and automatic polishing machines. Three operators hand-polished 30 of specimens with eggshell powder and pumice, while 10 were automatically polished (n = 5). A profilometer was used to determine the average surface roughness (Ra) after polishing. The Ra values for the specimens hand-polished were analyzed by using paired sample testing. The Ra values for all polished specimens were analyzed by using a one-way ANOVA. Differences between the two abrasive materials as well as the polishing system were determined by using the Bonferonni tests (p = 0.05).
Results and Conclusion For the PMMA specimens hand-polished, there was a strong connection in the Ra values. There were also significant variations in the Ra values across the three operators (p < 0.001). The automated technique created a substantially smoother surface than the traditional technique (p = 0.001). The greatest Ra values (0.20 µm) were found in specimens polished traditionally by using pumice, whereas the lowest Ra values (0.04 µm) were found in specimens polished mechanically with eggshell powder. The automated polishing system was the most effective polishing method when the Ra values were connected to the level of smoothness.
Converting Dissertation to Journal Article: Why and How?
Authors: Nayak Chaturbhuja 
Published: December 2021

AbstractResearch work embodied in a master's dissertation remains confined to a limited domain of the researcher, supervisor/co-supervisor and university library. It is desirable that the dissertation material be published in a reputed journal for various reasons including career growth of the researcher, recognition by the professional body, dissemination to a wider audience etc. Writing a research article from a dissertation does not mean just to shorten the latter mechanically or a cut-paste method. For the novice writer, it is a daunting task, but rewarding experience as well, to convert a dissertation to an article. Advice and support of the supervisor and senior colleagues having good experience in research as well as publication should be taken who can navigate the publication process, following the guidelines of the target journal. This article presents a synthesis of guidelines and practices to be followed by the researchers to see that the outcomes of their incessant and tireless efforts in preparing the dissertations be documented through publishable articles.
Impact of the National Policy on Integrative and Complementary Practices on Brazilian Public Homeopathy Services
Authors: Lemonica Renata , Patricio Karina Pavao 
Published: December 2021

Abstract
Background Homeopathy has been experiencing a period of expansion in Brazil due to its practical relevance in the face of new global and national health demands, culminating in the launch in 2006 of the National Policy for Integrative and Complementary Practices (NPICP) by the Ministry of Health of Brazil, which standardized and regularized the position of homeopathy within the Brazilian Unified Health System (SUS).
Aims To understand the impact of the guidelines proposed by the NPICP on homeopathy services in the SUS, specifically in the south-east region of Brazil, according to the perceptions of their managers.
Methods This is a descriptive, exploratory research study with a qualitative approach, conducted in homeopathy services in the south-east region of Brazil, through semi-structured interviews and with data processed using content analysis.
Results The data show the importance of the NPICP in regulating and offering homeopathy in the services studied. However, the NPICP's objective of promoting and fully developing integrative and complementary practices has not been achieved because it has failed to translate strategies into actions.
Conclusion Though important to the development of homeopathy services in any given location, policies stated in the NPICP were revealed to have limited impact on the implementation and development of new services. Without further legislation, training programs and appropriate budget allocation, new services will be unable to thrive and their users unable to benefit from a more comprehensive approach to healthcare.
National Survey Regarding Motivation and Conditions of Physicians Working in a Pediatric Cardiac Intensive Care Unit
Authors: Hanser Anja , Hofbeck Michael , Knies Ralf , Kumpf Matthias , Müller Nicole , Heimberg Ellen 
Published: December 2021

Abstract
Background The professional demands on the expertise in pediatric intensive care have continuously increased in recent years. Due to a lack of applicants, the staffing of a continuous shift service with qualified medical staff poses major challenges to the hospitals.
Methods A web-based questionnaire with 27 predominantly matrix questions on working conditions and motivation for working in this area was sent to pediatric hospitals throughout Germany.
Results 165 doctors responded to the survey. The average age of the participants was 35.2 years. The average weekend work load reported by 79% of the respondents was 2 weekends per month, 70% of the study participants performed five to seven night shifts per month. 92% of the respondents stated that they basically enjoyed working in the intensive care unit (ICU). When asked to prioritize the working conditions, an appreciative working atmosphere in the team was named as priority 1 by 57%, followed by good guidance in the independent performance of interventions (25%) and good working conditions (19%).
Discussion The survey result shows that neither aspects of work–life balance nor payments are the key issues selecting the interesting, but physically and emotionally demanding job in pediatric ICU.
Conclusion When evaluating vocational training in pediatric intensive care medicine, the immediate working atmosphere in the team with mutual respect and understanding and the guidance in training are more important than the general conditions.
Orbital Metastasis as Initial Clinical Presentation in a Patient of Hepatocellular Carcinoma – A Rare Case with Review of Literature
Authors: Rana Sakshi , Khosla Divya , Periasamy Kannan , Kapoor Rakesh , Bhardwaj Sunny , Madan Renu , Goyal Shikha , Rajwanshi Arvind 
Published: December 2021

AbstractOrbital metastasis, as the initial clinical presentation in hepatocellular carcinoma (HCC), is a rare manifestation. A 66-year-old male patient presented with a history of protrusion of the eyeballs, double vision, and swelling over the left side of the head for 8 months. Magnetic resonance imaging of the brain with orbit revealed a heterogeneous lesion in the left frontal lobe causing its destruction with intraorbital and intracranial extension. Triphasic contrast-enhanced computed tomography was suggestive of multiple hypodense areas in both lobes of the liver. Tissue diagnosis from the liver was suggestive of HCC. A diagnosis of multifocal HCC with orbital metastasis was made. The patient was treated with palliative radiotherapy and sorafenib. Orbital metastasis in HCC is rare. Prognosis is somber in such cases. The treatment should focus on providing palliation from symptoms.
Pregnancy Outcomes among Women with Class III Obesity with Pre-diabetic Early Hemoglobin A1C
Authors: Dillon Jacquelyn , Mitchell Courtney J. , Ellett Tressa , Siegel Anne , Denoble Anna E. , Dotters-Katz Sarah K. 
Published: December 2021

Objective We aimed to assess the risk of developing gestational diabetes mellitus (GDM) in women with a normal A1C (<5.7) compared with those with an A1C in the pre-diabetic range (5.7–6.4).
Study Design This study comprises of a retrospective cohort of non-anomalous singleton pregnancies with maternal body mass index (BMI) ≥40 at a single institution from 2013 to 2017. Pregnancies with multiple gestation, late entry to care, type 1 or 2 diabetes, and missing diabetes-screening information were excluded. The primary outcome was development of GDM. Secondary outcomes included fetal growth restriction, macrosomia, gestational age at delivery, large for gestational age, delivery BMI at delivery, total weight gain in pregnancy, induction of labor, shoulder dystocia, and cesarean delivery. Bivariate statistics were used to compare demographics, pregnancy complications, and delivery characteristics of women who had an early A1C < 5.7 and A1C 5.7 to 6.4. Multivariable analyses were used to estimate the odds of the primary outcome.
Results Eighty women (68%) had an early A1C <5.7 and 38 (32%) had a A1C 5.7 to 6.4. Women in the lower A1C group were less likely to be Black (45 vs. 74%, p = 0.01). No differences in other baseline demographics were observed. The median A1C was 5.3 for women with A1C < 5.7 and 5.8 for women with A1C 5.7 to 6.4 (p < 0.001). GDM was significantly more common in women with A1C 5.7 to 6.4 (3.8 vs. 24%, p = 0.002). Women with pre-diabetic range A1C had an odd ratio of 11.1 (95% CI 2.49–48.8) for GDM compared with women with a normal A1C.
Conclusion Women with class III obesity and a pre-diabetic range A1C are at an increased risk for gestational diabetes when compared with those with a normal A1C in early pregnancy.
Key Points
Preterm Singleton Birth Rate during the COVID-19 Lockdown: A Population-Based Study
Authors: Leibovitch Leah , Reichman Brian , Mimouni Francis , Zaslavsky-Paltiel Inna , Lerner-Geva Liat , Wasserteil Netanel , Sagiv Nadav , Daas Suha , Almashanu Shlomo , Strauss Tzipora 
Published: December 2021

Objective The aim of the study is to evaluate the effect of the coronavirus disease 2019 (COVID-19) pandemic national lockdown period on the rate of singleton preterm births in Israel.
Study Design This is a population-based cohort study of 3,41,291 singleton infants born in the months of January to July 2017 to 2020. Multivariable logistic regression analyses were used to estimate the influence of period and year on the rates of preterm births during the lockdown period (11th March − 5th May 2020) compared with rates before (January 1st 2020 − March 10th 2020), and after the lockdown (May 6th 2020–June 30th 2020) and to the corresponding periods in 2017to 2019.
Results During the lockdown period the preterm birth rate (primary outcome) decreased by 9.7% from 5.05 to 4.56% in the pre-lockdown period (p = 0.006), an adjusted decrease of −0.52% (95% confidence interval −0.89%; −0.15%), odds ratio 0.898 (95% confidence interval 0.832; 0.970).
Conclusion The rate of singleton preterm births declined by 9.7% during the COVID-19 pandemic national lockdown period in Israel.
Key Points
Scientific Publishing Differences between Sexes in Cardiology, Cardiac, and General Surgery
Authors: Färber Gloria , Alscher Leonhard , Heyne Estelle , Doenst Torsten , Schwarzer Michael 
Published: December 2021

Abstract
Background Research and scientific publications are important for the advancement of science but also for the individual career development. While women have become the majority of students in medicine we do not know about female presence and scientific activity in cardiac surgery. We thus aimed to compare scientific output of women and men in German University departments of cardiac surgery with cardiology departments focusing on the same organ and surgical departments not addressing the heart (general surgery) of 34 universities in Germany.
Methods Personnel working at University departments was identified on the institutions internet homepage in 2014. Publications in 2011 to 2013 on PubMed were identified. Author and manuscript characteristics were determined.
Results A lower proportion of women were working in cardiac surgery (25%) compared with cardiology (35%) and general (32%) surgery independent of executive function or academic degree. Scientifically active women published fewer manuscripts per capita than men both, in total and as first author. Additionally, the mean and the cumulated journal impact factor of the journals chosen was lower for women compared with men in cardiology but not in cardiac and general surgery.
Conclusion We conclude that the differences in scientific activity between women and men are more pronounced in cardiology compared with general and cardiac surgery, indicating that a higher proportion of women in a field does not result in reduced differences between sexes. The low number of women together with the lower number of manuscripts in cardiac surgery may render the appointment of women as directors challenging.