bluuebunny/crossref_metadata_2025_split huggingface dataset:
Electrochemical and Spectroscopic Studies on Triarylamine‐Polychlorotriphenylmethyl Dyads with Particularly Strong Triarylamine Donors
Authors: Breimaier Stefanie , Winter Rainer F. 
Published: July 2021

AbstractWe present two new donor‐acceptor dyads composed of a polychlorotriphenylmethyl radical (PTM.) as the acceptor (A) and bis(4‐dimethylaminophenyl)(phenyl)amine (TPAN) or 2,2’:6’,2’’:6’’,6‐trioxytriphenylamine (TOTA) as particularly electron‐rich triarylamine (TAA) donors (D). We assessed their electrochemical properties and electronic structures by cyclic voltammetry, UV/vis/NIR spectroscopy, EPR spectroscopy and quantum chemical calculations. By establishing the spectroscopic fingerprints of the oxidized and reduced forms, we probe for the possible coexistence of a zwitterionic TAA+‐PTM− valence tautomer (VT), besides neutral TAA‐PTM.. UV/vis/NIR and EPR spectroscopic studies at variable temperature and in various solvents however provide no indication for such equilibria. Quantitative spin counting experiments by EPR spectroscopy and quantum chemical calculations indicate that the one‐electron oxidized forms of these dyads possess an open‐shell singlet ground state which is energetically slightly below the triplet state
Attitudes and attitude certainty guiding pro‐social behaviour as a function of perceived elaboration
Authors: Moreno Lorena , Requero Blanca , Santos David , Paredes Borja , Briñol Pablo , Petty Richard E. 
Published: July 2021

AbstractThis research examined the effect of perceived elaboration on the relationship between attitudes and prosocial behaviour. Study 1 revealed that group fusion was more predictive of pro‐group behaviour (donation to in‐group members) when perceived elaboration was high rather than low. In Study 2, attitudes toward helping were more likely to guide prosocial behaviour (helping others in a learning task) for participants who reported higher levels of perceived elaboration. Studies 3 and 4 manipulated perceptions of elaboration, demonstrating that attitudes guided subsequent hiring decisions (Study 3) and an actual behavioural choice in a natural setting (Study 4), and that this link was stronger for those participants induced to believe that they engaged in high (vs. low) elaboration. Furthermore, Studies 2 and 4 revealed that the effects of perceived elaboration on attitude‐behaviour correspondence were mediated by attitude certainty. The present research reveals that prosocial behaviour can be facilitated by taking into consideration meta‐cognitive processes that accompany evaluation (perceived elaboration and attitude certainty).
A Rigidity/Flexibility Compatible Strategy to Improve the Stability and Durability of Flexible Electrochemical Sensor Based on a Polydimethylsiloxane Membrane Supported Prussian Blue@Carbon Nanotube Array
Authors: Jiang Tao , Nan Wenjing , Han Lianhuan , Wei Hang , Wang Miao , Peng Juan , Chen Yong , Hou Xu , Zhan Dongping 
Published: July 2021

AbstractMechanical fatigue and mechanical‐chemical effect can harm the stability and durability of flexible electrochemical sensors and electronic devices. To solve the problem, we propose a rigidity/flexibility compatible strategy by implanting Prussian blue into the carbon nanotube array supported by polydimethylsiloxane (PDMS). The PDMS membrane is soft and flexible, and counteracts the external force; meanwhile, Prussian Blue@Carbon Nanotube Hybrid is hard and rigid for the reliable detection of hydrogen peroxide. Consequently, the cyclic voltammetric behavior of Prussian blue keep almost constant during the continuous bending experiments. The results indicate that the rigidity/flexibility compatible strategy is instructive to improve the performance of flexible electrochemical sensors and electronic devices.
Validation study of no‐pillar mining method without advance tunneling: A case study of a mine in China
Authors: Yang Xiaojie , Huang Ruifeng , Yang Gang , Wang Yajun , Cao Jindong , Liu Jianning , He Maochao 
Published: July 2021

AbstractStudies regarding the reuse of a gob‐side roadway formed by the N00 longwall mining method are scarce. To investigate the mine pressure behavior characteristics during roadway reuse, the anchor cable force, roof‐to‐floor deformation, and working resistance of the hydraulic support obtained from the verification working face were analyzed. Test results show that the influence range of the mining‐induced pressure was 0‐90 m in front of the working face. The ratios of the first and periodic weighting steps between the entry‐retaining and non‐roof‐cutting sides were 20.25 and 1.94, respectively. However, the ratios of the ground pressure strengths at the two sides were 1.07 and 1.31, respectively. The results indicate that the monitored roadway can be classified into three deformation zones based on the severity of the mine pressure behavior: large, intermediate, and creep. The main roof between the adjacent working faces exhibited a failure type comprising the “O‐X” and “O‐Y” states, which resulted in an unconventional mine pressure behavior. This study provides insights into the N00 longwall mining method as well as important guidance for tackling similar geological conditions when using this mining method.
Investigation on the suppression characteristic of deoxidization gel foam on coal spontaneous combustion
Authors: Lu Xin‐xiao , Xue Xue , Wang Cheng‐yan , Shi Guo‐yu , Xing Yun , Han Yu 
Published: July 2021

SummaryMine fire caused by coal spontaneous combustion is one of the main safety problems in mining. For the purpose of developing a more effective inhibitor to suppress the coal spontaneous combustion, a compound deoxidization gel foam inhibitor was proposed by combining sodium dithionite deoxidizer with gel foam. An experimental platform was self‐built to evaluate the suppression characteristic of deoxidization gel foam. Experimental results showed that the deoxidization gel foam reduced the oxygen concentration to below 14% within 180 minutes. STA‐FTIR test indicated that the deoxidization gel foam raised the active temperature from 250.57°C to 275.18°C and reduced CO2 absorption peak from 0.2926 to 0.2201 at the reaction temperature 20°C. The activation energy was also increased from 85.69 to 95.59 kJ·mol−1 in thermal decomposition combustion that exhibited an excellent flame‐retardant efficacy on the coal, especially at the low temperature stage. CH3 and CH2 were reduced by 56.86% and 47.17% processed by deoxidization gel foam. Meanwhile, the significant reduction in the content of reductive functional groups indicated that the new inhibitor had a strong suppression capacity for coal spontaneous combustion. Based on above research, it is believed that this study will lay an important foundation in the widespread application of deoxidization gel foam technology for coal spontaneous combustion prevention in underground mines.
Transnasal transplantation of human induced pluripotent stem cell‐derived microglia to the brain of immunocompetent mice
Authors: Parajuli Bijay , Saito Hiroki , Shinozaki Youichi , Shigetomi Eiji , Miwa Hiroto , Yoneda Sosuke , Tanimura Miki , Omachi Shigeki , Asaki Toshiyuki , Takahashi Koji , Fujita Masahide , Nakashima Kinichi , Koizumi Schuichi 
Published: July 2021

AbstractMicroglia are the resident immune cells of the brain, and play essential roles in neuronal development, homeostatic function, and neurodegenerative disease. Human microglia are relatively different from mouse microglia. However, most research on human microglia is performed in vitro, which does not accurately represent microglia characteristics under in vivo conditions. To elucidate the in vivo characteristics of human microglia, methods have been developed to generate and transplant induced pluripotent or embryonic stem cell‐derived human microglia into neonatal or adult mouse brains. However, its widespread use remains limited by the technical difficulties of generating human microglia, as well as the need to use immune‐deficient mice and conduct invasive surgeries. To address these issues, we developed a simplified method to generate induced pluripotent stem cell‐derived human microglia and transplant them into the brain via a transnasal route in immunocompetent mice, in combination with a colony stimulating factor 1 receptor antagonist. We found that human microglia were able to migrate through the cribriform plate to different regions of the brain, proliferate, and become the dominant microglia in a region‐specific manner by occupying the vacant niche when exogenous human cytokine is administered, for at least 60 days.
Differential transformation method to determine heat transfer in annular fins
Authors: Umrao Sarwe Deepak , Kulkarni Vinayak S. 
Published: July 2021

AbstractFins are the extended surfaces that are utilized to afford a significant increase in the surface area for heat transference between a heated source and a colder ambient liquid. To enhance the heat transference rate from the exterior surface of a circular conduit, radial, or concentric annular fins are used. Fins are utilized in heat exchanging devices like superheaters, electrical equipment, computer CPU heat sinks, car radiators, refrigeration, and heat exchangers. Motivated by these applications, the current paper explores the thermal attribute of an annular fin with variable thermal conductivity. The framed equations are articulated in terms of nonlinear ordinary differential equations. One of the most effective techniques, the differential transformation method has been implemented to find the analytical solution. The domination of nondimensional parameters on the thermal gradient of the fin has been analyzed graphically. Furthermore, the variation in radial and tangential stress in an annular fin for various dimensionless parameters has been examined with a graphical explanation. Results reveal that the thermal gradient of fin increases for improved values of variable thermal conductivity parameters. The greater values of thermogeometric parameters result in a higher heat transfer.
Tile drainage causes flashy streamflow response in Ohio watersheds
Authors: Miller Samuel A. , Lyon Steve W. 
Published: July 2021

AbstractArtificial subsurface (tile) drainage is used to increase trafficability and crop yield in much of the Midwest due to soils with naturally poor drainage. Tile drainage has been researched extensively at the field scale, but knowledge gaps remain on how tile drainage influences the streamflow response at the watershed scale. The purpose of this study is to analyse the effect of tile drainage on the streamflow response for 59 Ohio watersheds with varying percentages of tile drainage and explore patterns between the Western Lake Erie Bloom Severity Index to streamflow response in heavily tile‐drained watersheds. Daily streamflow was downloaded from 2010 to 2019 and used to calculated mean annual peak daily runoff, mean annual runoff ratio, the percent of observations in which daily runoff exceeded mean annual runoff (TQmean), baseflow versus stormflow percentages, and the streamflow recession constant. Heavily‐drained watersheds (>40% of watershed area) consistently reported flashier streamflow behaviour compared to watersheds with low percentages of tile drainage (<15% of watershed area) as indicated by significantly lower baseflow percentages, TQmean, and streamflow recession constants. The mean baseflow percent for watersheds with high percentages of tile drainage was 20.9% compared to 40.3% for watersheds with low percentages of tile drainage. These results are in contrast to similar research regionally indicating greater baseflow proportions and less flashy hydrographs (higher TQmean) for heavily‐drained watersheds. Stormflow runoff metrics in heavily‐drained watersheds were significantly positively correlated to western Lake Erie algal bloom severity. Given the recent trend in more frequent large rain events and warmer temperatures in the Midwest, increased harmful algal bloom severity will continue to be an ecological and economic problem for the region if management efforts are not addressed at the source. Management practices that reduce the streamflow response time to storm events, such as buffer strips, wetland restoration, or drainage water management, are likely to improve the aquatic health conditions of downstream communities by limiting the transport of nutrients following storm events.
News media versus FRED‐MD for macroeconomic forecasting
Authors: Ellingsen Jon , Larsen Vegard H. , Thorsrud Leif Anders 
Published: July 2021

SummaryUsing a unique dataset of 22.5 million news articles from theDow Jones Newswires Archive, we perform an in depth real‐time out‐of‐sample forecasting comparison study with one of the most widely used data sets in the newer forecasting literature, namely theFRED‐MDdataset. Focusing on US GDP, consumption and investment growth, our results suggest that the news data contains information not captured by the hard economic indicators, and that the news‐based data are particularly informative for forecasting consumption developments.
The effects of edaravone, a free‐radical scavenger in lung injury induced by valproic acid demonstrated via different biochemical parameters
Authors: Bayrak Bertan B. , Yilmaz Sebahat , Hacihasanoglu Cakmak Neziha , Yanardag Refiye 
Published: July 2021

AbstractIn this study, we aimed to evaluate whether edaravone (EDA) has a protective role against valproic acid (VPA)‐induced lung damage via its antioxidative activity. Male Sprague–Dawley rats were split into four groups. Control (n = 8) rats; rats given EDA (30 mg kg−1 day−1;n = 10); rats given only (VPA, 500 mg kg−1 day−1;n = 10); rats given VPA + EDA (in the same dose and time) for 7 days. EDA and VPA were applied intraperitoneally. After 8 days, lung tissues were immediately taken from the rats. In lung homogenates, reduced glutathione, total antioxidant status levels, and superoxide dismutase, glutathione peroxidase, sodium/potassium ATPase, paraoxonase1, and carbonic anhydrase activities significantly abated, whereas catalase, glutathione reductase, glutathione‐S‐transferase activities insignificantly decreased in the VPA‐treated group. In contrast, lipid peroxidation, reactive oxygen species, and total oxidant status levels, glycoprotein and protein carbonyl contents, nitric oxide, hydroxyproline levels, and xanthine oxidase, lactate dehydrogenase, arginase, and prolidase activities significantly increased in the VPA‐given group. Administration of EDA caused the reverse effects. As a consequence, EDA prevented oxidative stress‐mediated lung injury via its robust antioxidant effects.
Chaperonin‐containing tailless complex polypeptide 1 subunit 6A correlates with increased World Health Organization grade, less isocitrate dehydrogenase mutation, and deteriorative survival of astrocytoma patients
Authors: Hu Yueyun , Fu Peng , Zhao Hongyang , Zhang Fangcheng , Jiang Xiaobing , Zhao Wohua , Lv Peng 
Published: July 2021

AbstractObjectiveChaperonin‐containing tailless complex polypeptide 1 subunit 6A (CCT6A) is reported to be an efficient prognostic biomarker in various cancers, but it is rarely reported in astrocytoma. Thus, this study aimed to evaluate the expression of CCT6A and its correlation with disease features and prognosis in astrocytoma patients.MethodsTotally, 198 astrocytoma patients who received surgery treatment were enrolled. CCT6A protein expression was determined in the tumor tissues fixed in formalin and embedded in paraffin (FFEP) by immunohistochemistry (IHC) assay. In addition, 133 out of 198 astrocytoma patients had fresh tumor tissues frozen in the liquid nitrogen for the determination of CCT6A mRNA expression by reverse transcription‐quantitative polymerase chain reaction.ResultsSixty‐nine (34.8%), 70 (35.4%), 46 (23.2%), and 13 (6.6%) astrocytoma patients had the CCT6A immunohistochemistry (IHC) score of 0–3, 4–6, 7–9, and 10–12, respectively. CCT6A protein expression was correlated with increased World Health Organization (WHO) grade (P < 0.001) and less isocitrate dehydrogenase (IDH) mutation (P = 0.002); meanwhile, CCT6A mRNA expression was only related to elevated WHO grade (P = 0.001). However, CCT6A protein and mRNA expression were not correlated with other clinical features and subsequent treatment modalities (all P > 0.05). Moreover, CCT6A protein high and CCT6A mRNA high were related to shorter accumulating overall survival (OS; both P < 0.05). CCT6A protein high was an independent factor for predicting the worse OS (hazard ratio: 1.821, P = 0.012).ConclusionChaperonin‐containing tailless complex polypeptide 1 subunit 6A correlates with elevated WHO grade and less IDH mutation; besides, CCT6A high expression is independently associated with unfavorable accumulating OS of astrocytoma patients.
Influence of short‐term temperature drops on sex‐determination in sea turtles
Authors: Porter Ellen , Booth David T. , Limpus Colin J. , Staines Melissa N. , Smith Caitlin E. 
Published: July 2021

AbstractAll sea turtles exhibit temperature‐dependent sex‐determination, where warmer temperatures produce mostly females and cooler temperatures produce mostly males. As global temperatures continue to rise, sea turtle sex‐ratios are expected to become increasingly female‐biased, threatening the long‐term viability of many populations. Nest temperatures are dependent on sand temperature, and heavy rainfall events reduce sand temperatures for a brief period. However, it is unknown whether these short‐term temperature drops are large and long enough to produce male hatchlings. To discover if short‐term temperature drops within the sex‐determining period can lead to male hatchling production, we exposed green and loggerhead turtle eggs to short‐term temperature drops conducted in constant temperature rooms. We dropped incubation temperature at four different times during the sex‐determining period for a duration of either 3 or 7 days to mimic short‐term drops in temperature caused by heavy rainfall in nature. Some male hatchlings were produced when exposed to temperature drops for as little as 3 days, but the majority of male production occurred when eggs were exposed to 7 days of lowered temperature. More male hatchlings were produced when the temperature drop occurred during the middle of the sex‐determining period in green turtles, and the beginning and end of the sex‐determining period in loggerhead turtles. Inter‐clutch variation was evident in the proportion of male hatchlings produced, indicating that maternal and or genetic factors influence male hatchling production. Our findings have management implications for the long‐term preservation of sea turtles on beaches that exhibit strongly female‐biased hatchling sex‐ratios.
Effects of participation in a U.S. trial of newborn genomic sequencing on parents at risk for depression
Authors: Schwartz Talia S. , Christensen Kurt D. , Uveges Melissa K. , Waisbren Susan E. , McGuire Amy L. , Pereira Stacey , Robinson Jill O. , Beggs Alan H. , Green Robert C. ,   The BabySeq Project Team, Bachmann Gloria A. , Rabson Arnold B. , Holm Ingrid A. 
Published: July 2021

AbstractMuch emphasis has been placed on participant's psychological safety within genomic research studies; however, few studies have addressed parental psychological health effects associated with their child's participation in genomic studies, particularly when parents meet the threshold for clinical concern for depression. We aimed to determine if parents’ depressive symptoms were associated with their child's participation in a randomized‐controlled trial of newborn exome sequencing. Parents completed the Edinburgh Postnatal Depression Scale (EPDS) at baseline, immediately post‐disclosure, and 3 months post‐disclosure. Mothers and fathers scoring at or above thresholds for clinical concern on the EPDS, 12 and 10, respectively, indicating possible Major Depressive Disorder with Peripartum Onset, were contacted by study staff for mental health screening. Parental concerns identified in follow‐up conversations were coded for themes. Forty‐five parents had EPDS scores above the clinical threshold at baseline, which decreased by an average of 2.9 points immediately post‐disclosure and another 1.1 points 3 months post‐disclosure (both p ≤ .014). For 28 parents, EPDS scores were below the threshold for clinical concern at baseline, increased by an average of 4.7 points into the elevated range immediately post‐disclosure, and decreased by 3.8 points at 3 months post‐disclosure (both p < .001). Nine parents scored above thresholds only at 3 months post‐disclosure after increasing an average of 5.7 points from immediately post‐disclosure (p < .001). Of the 82 parents who scored above the threshold at any time point, 43 (52.4%) were reached and 30 (69.7%) of these 43 parents attributed their elevated scores to parenting stress, balancing work and family responsibilities, and/or child health concerns. Only three parents (7.0%) raised concerns about their participation in the trial, particularly their randomization to the control arm. Elevated scores on the EPDS were typically transient and parents attributed their symptomatology to life stressors in the postpartum period rather than participation in a trial of newborn exome sequencing.
Renal involvement in a patient with the chronic visceral subtype of acid sphingomyelinase deficiency resembles Fabry disease
Authors: Eskes Eline C. B. , van der Lienden Martijn J. C. , Roelofs Joris J. T. H. , Vogt Liffert , Aerts Johannes M. F. G. , Aten Jan , Hollak Carla E. M. 
Published: July 2021

AbstractAcid sphingomyelinase deficiency (ASMD) is a lysosomal storage disease (LSD) in which sphingomyelin accumulates due to deficient acid sphingomyelinase. In the chronic visceral subtype, organ manifestations are generally limited to the spleen, liver, and lungs. We report a male patient with the chronic visceral subtype who developed proteinuria and renal insufficiency at the age of 49. In renal tissue, foam cells were observed in the glomeruli as well as sphingomyelin accumulation within podocytes, mesangial cells, endothelial cells, and tubular epithelial cells. Although macrophages are the primary storage cells in both ASMD and Gaucher disease, comparison to the histopathological findings in Gaucher and Fabry disease revealed a diffuse storage pattern in multiple renal cell types, closer resembling the pattern found in Fabry disease.