bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rare Case Report of Primary Gastric Melanoma
Authors: Ashwini K. T. , Mahesh Deepa , Sandeep M. S. 
Published: May 2021

Gastric melanomas are usually metastatic, and primary is almost rare entity.
Present case is a rare malignant melanoma of the gastric region with barely reported cases in the literature. A 65 year old male presented with pain abdomen and melena He was evaluated with relevant investigation. UGI endoscopy and PETCT shows large polypoidal irregular gastric mass in the proximal curvature extending upto gastroesophageal junction. Endoscopic biopsy a ulcero-infiltrating tumour, Individual cells are large, round, having moderately pleomorphic, hyperchromatic nuclei with prominent eosinophilic nucleoli and moderate eosinophilic cytoplasm. Immunohistochemistry of S100 and HMB45 was positive and negative for CK7 and CK20.
Early diagnosis of primary gastric melanoma allows for better prognosis of the patient from the right intervention.
Vitamin D Deficiency in the Elderly Patients and Role of Vitamin D in the Prevention of COVID-19 Infection
Authors: Khan Nauman , Tahmina . 
Published: May 2021

SARS Covid'19 is declared as a global pandemic by World Health Organization [1]. The aim of this short report is to find out the association of Vitamin D in prevention of Covid'19 in elderly patients who are already having other co-morbidities. People of any age are susceptible to Corona virus but the elderly patients and patients with chronic underlying diseases are at higher risk. Many elderly patients with COVID-19 are at risk of mal-nutrition [2].
Vitamins are of two types, Lipid soluble vitamins and water-soluble vitamins [3]. Lipid soluble vitamins can be stored in the body while water soluble vitamins cannot be stored in the body, hence needed to take regularly [4]. Vitamin D is a lipid soluble vitamin also it can be synthesized by our own body.
Safety and Efficacy of Bivalirudin in Diabetic Acute Coronary Syndrome (ACS) Patients Undergoing Percutaneous Coronary Intervention (PCI)
Authors: Golam Mostofa A.B.M. , Parvin Tanjima , Mandal Mohammad Rayhan Masum , Afrin Rawnak , Ahsan Syed Ali 
Published: May 2021

Objective: To determine and compare the incidence of in-hospital and 30-day hemorrhagic complications and major adverse cardiac events (MACEs) as evidence of safety and efficacy using Bivalirudin versus Heparin in diabetic acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI) in a tertiary care cardiac hospital.
Background: Prevention of hemorrhagic complications has emerged as a priority in patients undergoing PCI in addition to suppressing thrombotic complications. This goal is challenging to achieve in diabetic ACS patients as DM itself is a prothrombotic state with more pronounced vascular injury response and have a worse outcome after PCI compared with non-diabetic patients. In patients with ACS, Bivalirudin has been shown to result in similar rates of composite ischemia as Heparin plus GPI (GP IIb /IIIa inhibitor), while significantly reducing major bleeding and has received class I recommendation for PCI. Whether Bivalirudin is safe and effective in diabetic ACS patients undergoing PCI, as compared with Heparin (UFH) monotherapy, is unknown.
Methods: 218 diabetic ACS patients (age>18 years and ≤ 75 years) who underwent PCI from May 2018 to April 2019 at UCC, BSMMU, Dhaka, Bangladesh were randomly assigned to have UFH or Bivalirudin. Before the guide wire crossed the lesion, 111 patients in the UFH group received a bolus of 70-100 U/kg (targeted activated clotting time, ACT: 200-250 s). 107 patients in the Bivalirudin group received a loading dose of 0.75 mg/kg, followed by an infusion of 1.75 mg/kg/h for up to 4 hours. Dual antiplatelet (DAPT) loading as Aspirin 300 mg plus P2Y12 inhibitors (Clopidogrel 600 mg or Prasugrel 60 mg or Ticagrelor 180 mg) was given in all patients before the procedure. The maintenance dose of DAPT was continued for at least one month and patients were followed telephonically up to 30 days. The outcome measures were in-hospital and 30-day hemorrhagic complications and MACEs [death, MI, target vessel revascularization (TVR) and stroke].
Results: Patients treated with Bivalirudin compared with Heparin had a significantly lower in-hospital incidence of QMI (0% vs. 6%; p=0.03) and major bleeding (0% vs. 7%; p=0.02). However, the incidence of cardiac death, stent thrombosis, TVR were no differences between the groups (p>0.05). There was only one NQMI in the Bivalirudin group as opposed to 8% in the Heparin group in 30 days following stenting (p=0.04). No other adverse effects were found significantly different between groups in 30 days of PCI.
Conclusion: In this small scale, prospective, randomized controlled study of diabetic ACS patients undergoing PCI in a single center showed that Bivalirudin is safe and effective as it reduces immediate and short-term hemorrhagic complications as well as MACEs as compared with Heparin.
Neuropsychological Correlates and Frequency of Tinnitus in Patients Injured in Motor Vehicle Accidents
Authors: Cernovsky Zack Z. , Mann Stephan C. , Velamoor Varadaraj R. 
Published: May 2021

Background: There is a lack of data on the frequency and neuropsychological correlates of tinnitus in distinct clinical populations such as persons injured in high impact motor vehicle accidents (MVAs).
Method: Tinnitus severity and frequency were analyzed statistically in de-identified data of 106 post-MVA patients (mean age=39.5, SD=13.1; 31 males and 75 females). Correlations of tinnitus to the patients’ scores on the Rivermead Post-Concussion Symptoms Questionnaire, Subjective Neuropsychological Symptoms Scale (SNPSS), Brief Pain Inventory, Insomnia Severity Index, PTSD measure (PCL-5), and to ratings of depression, anger, and anxiety on the Whiplash Disability Questionnaire were evaluated. The patients were interviewed an average of 53.6weeks (SD=39.9) after their MVA; all continued to suffer from post-MVA symptoms requiring therapy.
Results: Tinnitus was reported by 70 of the 106 post-MVA patients (66%). Slightly less than a half of the 70 rated their tinnitus as “frequent” or “persistent” and slightly more than a half as “occasional.”
With respect to Rivermead and SNPSS items, the severity and frequency of tinnitus correlated significantly (at p<.01, 2-tailed) with oversensitivity to light, restlessness, word finding difficulty, hand tremor, stutter, and instances of reduced muscular control over hand or arm (rs ranging from .28 to .37). Tinnitus severity correlated also with tingling in the limbs (r=.31), and with impaired balance (r=.28). Tinnitus frequency correlated also with difficulty articulating words (r=.28). Tinnitus also significantly correlated with ratings of pain and of insomnia (rs ranging from .26 to .32), but not with variables such as PTSD, depression, or anxiety.
Discussion and Conclusions: Tinnitus is correlated with some aspects of whiplash trauma and the post-concussion syndrome. However, the size of these relationships is rather weak.
Comparative Stereological Analysis of Intracranial Volume fractions among Patients with Brain Atrophy and Normal Pressure Hydrocephalus from a Nigerian Population
Authors: Abba Mohammed , Ugwu Anthony Chukwuka , Asomugha Azuoma L. , Ismail Hassan 
Published: May 2021

Background: Differentiation between symptoms of normal pressure hydrocephalus (NPH) and other neurodegenerative disorders such as Brain Atrophy (BA) are usually confusing. Available diagnostic methods are invasive while the few non-invasive methods did not take care of potential factors known to influence intracranial volumes. We, therefore, aim to determine and compare the intracranial volume fractions among patients with NPH and BA.
Methods: This was a prospective, cross-sectional age-matched control study among consenting patients that were diagnosed with NPH, BA and healthy control in Aminu Kano Teaching Hospital from March 2018 to November 2020. Each patient was routinely examined with CT-Scan; However, control participants were from other reasons. Participants with a medical history known to influence the intracranial volume were excluded. Volume estimation was based on a stereological Cavalieri method and three volume fractions were determined mathematically for each of the group. Test-point computing was facilitated through a locally developed software (voXas_2018). Ethical approval was sort prior to the study.
Results: Patients with NPH have higher total CSF: brain ratio, intraventricular volume: brain ratio and extra-ventricular: brain ratio. Similar pattern was exhibited according to age grouping, except in the older age category where BA volume fractions were higher.
Conclusion: Age, gender and statue are known to influence intracranial volumes. We controlled their potential effects through age-matched control of participants between groups and the use of intracranial volume ratios for objective diagnosis of NPH and BA. However, Tcsf:Br and InV:Br volume fraction ratios were found to be reliable indices for distinguishing patients with NPH and BA.
A Rare Case of Synchronous Ovarian Adenocarcinoma and Squamous Cell Carcinoma of Cervix
Authors: Nadarajan Logeswary , Oo Lee Saw J , Nusee Zalina 
Published: May 2021

Synchronous tumours of gynaecological malignancies occur rarely and most of these cases are represented by synchronous ovarian and endometrial cancer. Synchronous malignancies of cervix and ovary are rare with poor prognosis. Only few cases of synchronous cancer of cervix and ovary are found in the literature as case reports. Here, we report a case of a 63 year old patient who was diagnosed with synchronous squamous cell carcinoma of cervix and high grade serous carcinoma of ovary in which her clinical presentation, investigation and intraoperative findings were atypical. Patient presented with postmenopausal bleeding and mass per abdomen. Pipelle sampling revealed squamous cell carcinoma of cervix. Examination under anaesthesia noted endocervical growth measuring 3×4 cm with endoluminal extension into the whole endometrial cavity. Computerized tomography (CT) imaging showed left ovarian mass measuring 10.0×11.7 cm. Uterine corpus involvement in this case mislead us to the initial diagnosis of ovarian metastasis in cervical cancer. The distinct histopathological features of the ovary, cervix and endometrial lesion post operatively helped in establishing the diagnosis of two separate primaries which was synchronous cervical and ovarian cancer rather than metastatic spread of one primary malignancy.
Interim Prosthesis for Repositioning of Mandible in a Hemimandibulectomy Patient: A Case Report
Authors: Kaur Mandeep , Kaura Sakshi M. , Sharma Amit , Kaur Simarpreet 
Published: May 2021

Background: Squamous cell carcinoma is prevalent in middle asia due to prevalence of tobacco chewing. Management includes removal of mandibular bone along with adjacent muscles and nerves. Mandible is attached to cranium with the support of muscles. Removal of muscles results in deviation of mandible and loss of occlusion, which is necessary for functions such as chewing, swallowing and to some extent in speech. Prosthetic appliances help in restoration of position of mandible and thus restoring the function.
Case Report: This is a case of 58 year old male with hemimandibulectomy due to moderately differentiated squamous cell carcinoma.
Treatment Plan: Interim guiding prosthesis was planned for mandibular repositioning as the patient did not report before the surgical excision.
Conclusion: a definitive management would be undertaken by using cast partial dentures after mandibular repositioning with interim prosthesis is done.
Additive Effect of Sulfantil to Lidocain and Bupivacain for Supraclavicular Brachial Plexus Block
Authors: Lodhe D. S. , Akulwar V. V. , Deshmukh S. 
Published: May 2021

Purpose: We evaluated the effect of adding Sufentanil to the mixture of Lidocaine and Bupivacaine used for supraclavicular brachial plexus block in reducing postoperative pain.
Method: This double-blind clinical intervention trial was conducted in 2007. Patients scheduled to undergo upper limb orthopedic surgeries under supraclavicular brachial plexus block were recruited. Participants of one arm were given the mixture of Sufentanil, lidocaine, and bupivacaine (Group S) while those of the other arm were given the mixture of later two drugs (Group C). Postoperative pain assessment was done every hour postoperatively till the first administration of systemic analgesic. We used a subjective pain score and duration of lack of muscle movement as a parameter to judge outcomes. The mean and standard deviation were compared of both arms.
Result: We included 50 patients in both arms. The mean duration of the motor blockade in group S and C were 342.8 (± 145.4) and 171.1 (±50.2) minutes respectively. The additive effect of Sufentanil in motor blockage was 171.7 (95% CI 128.5–214.9) (p = 0.1×10-6). The mean duration of analgesia in group S and C were 892 (±34.7) and 350 (±72.1) minutes respectively. The additive effect of Sufentanil in analgesia was 542 (95% CI 524–559) (p = 0.1×10-6). In group S, one patient developed cardiac pain following pneumothorax and two had temporary Horner syndrome.
Conclusion: Analgesia in the postoperative period can be enhanced with the addition of Sufentanil (an opioid) to local anesthetics in supraclavicular brachial plexus block.
Maxillary Sinus Mucopyocele: About an Endoscopic Management
Authors: Lakhdar Y. , Hakimi M. , Benhoumad O. , Rochdi Y. , Raji A. 
Published: May 2021

Introduction: Mucocele is a benign but expansive cystic formation, lined by a respiratory epithelium. When its content is infected, it is called a mucopyocele. It usually develops in the frontal-ethmoid complex. The maxillary sinus location is exceptional.
Case report: a 43 year old man, presented with chronic unilateral nasal obstruction, purulent rhinorrhea and anosmia. Rhinoscopy showed a bulge in the middle meatus. The computed tomography (CT) showed complete filling of the left maxillary with low-density mass. Magnetic resonance imaging (MRI) confirmed the diagnosis of mucpyeocele of the left maxillary sinus. Patient underwent endoscopic endonasal marsupialization with complete recovery.
Conclusion: Mucopyocele of the maxillary sinus is a benign rare lesion, however destructive. A radiological assessment is essential to guide the choice of surgical treatment. The endonasal route remains the reference treatment for this pathology.
An Infectious Cause of Esophagobronchial Fistula
Authors: Momen Abdul Basit Ibne , Faaria Rafa , Khan Farhana , Saber Sadia , Alam Md Tarek 
Published: May 2021

An infected cause of esophagobronchial fistula between left bronchus and esophagus is mentioned who is a 32 year old male with a history of smoking and I/V drug abuse. The scientific reasons for suspecting an esophagogastric-bronchial fistula in an adult are discussed, as well as a description of the different etiologies of this condition. Intra thoracic malignancy, injuries, and infections are the most frequent causes of esophageal-bronchial fistula. These fistulas are caused by the rupturing of caseous peribronchial lymph nodes into adjacent structures such as the esophagus and bronchi. It's difficult to determine what the right course of action is. Such cases are surgically treated, while others can only be treated conservatively. Diagnosing bronchoesophageal fisula is usually challenging and often delayed, since there have not been many cases found. Any patient who presents with cough after deglutition should be suspected of having an esophagobronchial fistula, and tubercular origin should also be considered, particularly in an endemic region, since early diagnosis and treatment with anti-tubercular therapy typically results in resolution.
PENGGUNAAN JENIS MEDIA DAN PERLAKUAN PUPUK UNTUK PERTUMBUHAN ANGGREK DENDROBIUM
Authors: Lianawati Ida Ayu Meva , Adriani Astiti Ni Putu , Suriani Ni Luh 
Published: May 2021

ABSTACT
Reseach on dendrobium orchids was planted in the media of wood charcoal and coconut fibers and it is needed with Gandasil B fertilizer wood charcoal and coconut fiber media and is needed with Gandasil B and Multitonik fertilizer. This study aims to determine the effect of media and fertilizer on orchid growth and to determine pests and diseases in Dendrobium orchid plants. This reseach was conducted in May until July 2019 in the Plant Physiology Laboratory Biologi Prodi Studi Biologi Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Udayana. Qualitative and quantitative data are used that combine the Gandasil B fertilizer and fibers and wood charcoal media Fertilizer Gandasil B fertilizer with concetration G0 (0 g L-1), G2 (20 g L-1), G3 (30 g L-1), G4 (40 g L-1), G5 (50 g L-1). Fertilizer Multitonik M0 (0 g L-1), M1 (1,1 g L-1), M2 (1,2 g L-1), M3 (1,3 g L-1), M4 (1,4 g L-1), M5 (1,5 g L-1). Each fertilizer concentration was repeated 6 times. The results showed the best orchid growth was found in the use of Multitonik fertilizer and the best orchid growth was found in the use of Multitonik number of leavers and root growth were found in the use of coconut fibers media
STRUKTUR DAN KOMPOSISI GULMA PADA TANAMAN PADI (Oryza sativa L.) DI DESA CEMPAGA KECAMATAN BANGLI KABUPATEN BANGLI
Authors: Subagia Putri Ida Ayu Gede Sutha Windari , Joni Martin , Sundra I Ketut 
Published: May 2021

INTISARI
Keberadaan gulma pada tanaman padi akan menyebabkan penurunan produksi apabila gulma tidak dikendalikan secara efektif, karena dapat mempengaruhi pertumbuhan dan menurunkan produksi tanaman pangan. Penelitian ini bertujuan untuk mengetahui keanekaragam jenis gulma yang tumbuh pada tanaman padi (Oryza sativa L.) di Desa Cempaga, Kecamatan Bangli, Kabupaten Bangli, mengetahui jenis gulma yang tumbuh pada tanaman padi (Oryza sativa L.), dan jenis gulma apakah yang dominan pada tanaman padi (Oryza sativa L.). Penelitian ini dilaksanakan di Desa Cempaga Kecamatan Bangli Kabupaten Bangli pada bulan Maret-Mei 2020. Pengumpulan data dilakukan dengan analisis vegetasi menggunakan metode kuadrat dengan cara random menggunakan lotre atau undi dimana pengambilan sampel dilakukan sebanyak tiga kali yaitu pada minggu ke-8, ke-10, dan ke-12 dengan interval waktu pengambilan yaitu sekali dalam 2 minggu sehingga jumlah sampel yang diambil setiap 2 minggu yaitu 15 plot dengan ukuran 1x1m, dan data yang diambil yaitu jenis gulma yang terdapat didalam plot. Hasil pengamatan keberadaan jenis gulma menunjukkan bahwa jenis-jenis gulma yang tumbuh di lokasi penelitian cukup bervariasi, terdapat 781 individu, 12 jenis dan 8 suku, dimana gulma yang paling banyak muncul di plot yaitu tumbuhan Pusut-pusut muncul di 23 plot dan memiliki dominansi relatif yaitu sebesar 49,31%, sedangkan gulma yang paling sedikit muncul yaitu Paku Rawa hanya muncul di satu plot dengan memiliki nilai dominansi relatif yaitu 0,00%. Dimana artinya tumbuhan yang paling berpotensi mengganggu tanaman pokok yaitu tumbuhan Pusut-pusut dengan pola penyebaran yang mengelompok. Nilai INP tertinggi terdapat pada jenis gulma Pusut-pusut dengan nilai sebesar 103.45%.

Kata Kunci : Desa Cempaga, Gulma, Padi Sawah
PERTUMBUHAN DAN HASIL RUMPUT GAJAH (Pennisetum purpureum cv. Taiwan) YANG DIBERI PUPUK KASCING DENGAN DOSIS BERBEDA
Authors: Keliat Juanda Putra , Kusumawati N. N. Candraasih , Trisnadewi A. A. A. S. 
Published: May 2021

Penelitian dilakukan bertujuan untuk mengetahui pertumbuhan dan hasil rumput gajah (Pennisetumpurpureum cv. Taiwan) yang diberi pupuk kascing dengan dosis berbeda. Percobaan dilakukan di RumahKaca, Stasiun Penelitian Sesetan, Fakultas Peternakan, Universitas Udayana. Percobaan berlangsung selama8 minggu, menggunakan rancangan acak lengkap (RAL) dengan lima perlakuan dan enam ulangan sehinggaterdapat 30 unit percobaan. Perlakuan yang diberikan adalah dosis pupuk kascing yang terdiri atas 0 t ha-1, 5 t ha-1, 10 t ha-1, 15 t ha-1, dan 20 t ha-1. Variabel yang diamati yaitu variabel pertumbuhan, hasil dankarakteristik tumbuh. Variabel pertumbuhan tinggi tanaman tertinggi pada dosis 20 t ha-1. Jumlah daundan anakan menunjukkan berbeda tidak nyata. Variabel hasil pada pemberian pupuk kascing meningkatkan secara nyata berat kering daun, batang, akar dan total hijauan dan tertinggi pada dosis 20 t ha-1tumbuh tidak berbeda nyata pada nisbah berat kering daun dengan berat kering batang dan nisbah berat kering total hijauan dengan berat kering akar. Luas daun per pot tertinggi pada dosis 20 t ha-1. Dapat disimpulkan bahwa rumput gajah (Pennisetum purpureum cv. Taiwan) yang diberi pupuk kascing pada dosis 20 t ha-1 memberikan pertumbuhan dan hasil yang lebih baik.Kata kunci: pertumbuhan, hasil, rumput gajah, pupuk kascing
RESPONS Clitoria ternatea L. TERHADAP BERBAGAI LEVEL DOSIS DAN LAMA WAKTU INKUBASI INOKULAN RHIZOBIUM
Authors: Doni Markarius , Suarna I Wayan , Kusumawati N. N. Candraasih 
Published: May 2021

Penelitian bertujuan untuk mengetahui respons Clitoria ternatea L. terhadap berbagai level dosis dan lamawaktu inkubasi inokulan Rhizobium, serta untuk mengetahui interaksi antara level dosis inokulan Rhizobiumdan lama inkubasi terhadap respon tanaman C. ternatea. Percobaan dilakukan di Rumah Kaca, StasiunPenelitian Sesetan, Fakultas Peternakan, Universitas Udayana di Denpasar, Bali. Percobaan berlangsungselama 3 bulan, menggunakan rancangan acak lengkap (RAL) pola faktorial. Faktor pertama terdiri atas level dosis Rhizobium yaitu: 0 g kg-1 biji (D0), 7,5 g kg-1 biji (D1), 15 g kg-1 biji (D2) 22,5 g kg-1 biji (D3), faktor kedua terdiri atas lama waktu inkubasi yaitu: 1 jam (W1), 2 jam (W2), 3 jam (W3). Setiap perlakuan diulang sebanyak empat kali, sehingga terdapat 48 unit percobaan. Variabel yang diamati yaitu variabel pertumbuhan, variabel hasil dan variabel karakteristik. Hasil penelitian menunjukkan bahwa terjadi interaksi antara level dosis dan lama waktu inkubasi terhadap variabel bintil akar efektif. Level dosis 22,5 g kg-1hasil terbaik pada variabel tinggi tanaman, jumlah daun, jumlah cabang, bintil akar efektif, berat kering daun, berat kering batang, berat kering akar, berat kering total hijauan dan luas daun. Perlakuan waktuinkubasi 3 jam memberikan hasil tertinggi pada variabel bintil akar efektif, berat kering batang dan berat kering total hijauan. Berdasarkan hasil penelitian dapat disimpulkan bahwa terjadi interaksi antara leveldosis Rhizobium dan lama inkubasi terhadap variabel bintil akar efektif dan perlakuan level dosis Rhizobium22,5 g kg-1 biji dan lama waktu 3 jam memberikan pengaruh terbaik terhadap tanaman C. ternatea.Kata kunci: Clitoria ternatea, dosis inokulan Rhizobium, waktu inkubasi