bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mid-infrared cascaded stimulated Raman scattering and flat supercontinuum generation in an As-S optical fiber pump at 2 µm
Authors: Wang Fang , Zhou Xue , Zhang Xuenan , Yan Xin , Li Shuguang , Suzuki Takenobu , Ohishi Yasutake , Cheng Tonglei 
Published: June 2021

We demonstrate broadband mid-infrared cascaded stimulated Raman scattering (SRS) and flat supercontinuum (SC) generation in a chalcogenide optical fiber made from

A
s

2

S

5

glass. By using a 2 µm nanosecond laser as the pump source, mid-infrared cascaded SRS up to six orders ranging from 2149 to 3425 nm was experimentally observed, and this all-fiber Raman laser operating at 3.43 µm was realized for the first time to our knowledge. By introducing a 2 µm femtosecond laser as the excited source, the broadband flat mid-infrared SC with the spectral range of

∼

10

d
B

(from

∼

1030

to 3441 nm) was observed. Our results verify that the

A
s

2

S

5

optical fibers possess promising applications for tunable mid-infrared Raman fiber lasers and SC light sources pumped by 2 µm pulsed lasers.
Hypotension during endovascular treatment under general anesthesia for acute ischemic stroke
Authors: Collette Sabine L. , Uyttenboogaart Maarten , Samuels Noor , van der Schaaf Irene C. , van der Worp H. Bart , Luijckx Gert Jan R. , Venema Allart M. , Sahinovic Marko M. , Dierckx Rudi A. J. O. , Lingsma Hester F. , Kappen Teus H. , Bokkers Reinoud P. H. ,   MR CLEAN Registry Investigators
Published: June 2021

Objective
The effect of anesthetic management (general anesthesia [GA], conscious sedation, or local anesthesia) on functional outcome and the role of blood pressure management during endovascular treatment (EVT) for acute ischemic stroke is under debate. We aimed to determine whether hypotension during EVT under GA is associated with functional outcome at 90 days.

Methods
We retrospectively collected data from patients with a proximal intracranial occlusion of the anterior circulation treated with EVT under GA. The primary outcome was the distribution on the modified Rankin Scale at 90 days. Hypotension was defined using two thresholds: a mean arterial pressure (MAP) of 70 mm Hg and a MAP 30% below baseline MAP. To quantify the extent and duration of hypotension, the area under the threshold (AUT) was calculated using both thresholds.

Results
Of the 366 patients included, procedural hypotension was observed in approximately half of them. The occurrence of hypotension was associated with poor functional outcome (MAP <70 mm Hg: adjusted common odds ratio [acOR], 0.57; 95% confidence interval [CI], 0.35–0.94; MAP decrease ≥30%: acOR, 0.76; 95% CI, 0.48–1.21). In addition, an association was found between the number of hypotensive periods and poor functional outcome (MAP <70 mm Hg: acOR, 0.85 per period increase; 95% CI, 0.73–0.99; MAP decrease ≥30%: acOR, 0.90 per period; 95% CI, 0.78–1.04). No association existed between AUT and functional outcome (MAP <70 mm Hg: acOR, 1.000 per 10 mm Hg*min increase; 95% CI, 0.998–1.001; MAP decrease ≥30%: acOR, 1.000 per 10 mm Hg*min; 95% CI, 0.999–1.000).

Conclusions
Occurrence of procedural hypotension and an increase in number of procedural hypotensive periods were associated with poor functional outcome, whereas the extent and duration of hypotension were not. Randomized clinical trials are needed to confirm our hypothesis that hypotension during EVT under GA has detrimental effects.
Pharmacist-led educational interventions provided to healthcare providers to reduce medication errors: A systematic review and meta-analysis
Authors: Jaam Myriam , Naseralallah Lina Mohammad , Hussain Tarteel Ali , Pawluk Shane Ashley 
Published: June 2021

Introduction
Medication errors are avoidable events that can occur at any stage of the medication use process. They are widespread in healthcare systems and are linked to an increased risk of morbidity and mortality. Several strategies have been studied to reduce their occurrence including different types of pharmacy-based interventions. One of the main pharmacist-led interventions is educational programs, which seem to have promising benefits.

Objective
To describe and compare various pharmacist-led educational interventions delivered to healthcare providers and to evaluate their impact qualitatively and quantitatively on medication error rates.

Methods
A systematic review and meta-analysis was conducted through searching Cochrane Library, EBSCO, EMBASE, Medline and Google Scholar from inception to June 2020. Only interventional studies that reported medication error rate change after the intervention were included. Two independent authors worked through the data extraction and quality assessment using Crowe Critical Appraisal Tool (CCAT). Summary odds ratios (ORs) with 95% confidence intervals (CIs) were calculated using a random-effects model for rates of medication errors. Research protocol is available in The International Prospective Register of Systematic Reviews (PROSPERO) under the registration number CRD42019116465.

Results
Twelve studies involving 115058 participants were included. The two main recipients of the educational interventions were nurses and resident physicians. Educational programs involved lectures, posters, practical teaching sessions, audit and feedback method and flash cards of high-risk abbreviations. All studies included educational sessions as part of their program, either alone or in combination with other approaches, and most studies used errors encountered before implementing the intervention to inform the content of these sessions. Educational programs led by a pharmacist were associated with significant reductions in the overall rate of medication errors occurrence (OR, 0.38; 95% CI, 0.22 to 0.65).

Conclusion
Pharmacist-led educational interventions directed to healthcare providers are effective at reducing medication error rates. This review supports the implementation of pharmacist-led educational intervention aimed at reducing medication errors.
The effect of mental health on sleep quality of front-line medical staff during the COVID-19 outbreak in China: A cross-sectional study
Authors: Yue Leiyu , Zhao Rui , Xiao Qingqing , Zhuo Yu , Yu Jianying , Meng Xiandong 
Published: June 2021

Background
The 2019 coronavirus disease (COVID-19) pandemic is a public health emergency of international concern and poses a challenge to the mental health and sleep quality of front-line medical staff (FMS). The aim of this study was to investigate the sleep quality of FMS during the COVID-19 outbreak in China and analyze the relationship between mental health and sleep quality of FMS.

Methods
From February 24, 2020 to March 22, 2020, a cross-sectional study was performed with 543 FMS from a medical center in Western China. A self-reported questionnaire was used to collect data anonymously. The following tests were used: The Self-Rating Anxiety Scale (SAS) for symptoms of anxiety, the Beck Depression Inventory (BDI) for depressive symptoms, and the Pittsburgh Sleep Quality Index (PSQI) for sleep quality assessment.

Results
Of the 543 FMS, 216 (39.8%) were classified as subjects with poor sleep quality. Anxiety (P<0.001), depression (P<0.001), and the prevalence of those divorced or widowed (P<0.05) were more common in FMS with poor sleep quality than in participants with good sleep quality. The FMS exhibiting co-occurrence of anxiety and depression were associated with worse scores on sleep quality than those medical staff in the other three groups/categories. The difference in sleep quality between the FMS with only depression and the FMS experiencing co-occurrence of anxiety and depression was statistically significant (P<0.05). However, there was no significant difference in sleep quality between the FMS experiencing only anxiety and the FMS with co-occurrence of anxiety and depression (P > 0.05).

Conclusions
During the COVID-19 pandemic, there was a noteworthy increase in the prevalence of negative emotions and sentiments among the medical staff, along with poor overall sleep quality. We anticipate that this study can stimulate more research into the mental state of FMS during outbreaks and other public health emergencies. In addition, particular attention must be paid to enhance the sleep quality of FMS, along with better planning and support for FMS who are continuously exposed to the existing viral epidemic by virtue of the nature of their profession.
Diagnostic usefulness of the spot urine sodium/potassium ratio in cirrhotic patients with ascites
Authors: Lee Jin Wook , Hwang Jae Seok , Chung Woo Jin , Lee Heon Ju , Park Jung Gil , Lee Chang Hyeong , Kim Byung Seok , Song Jeong Eun , Kweon Young Oh , Tak Won Young , Park Soo Young , Jang Se Young , Suh Jeong Ill , Jang Byoung Kuk 
Published: June 2021

Background and aims
The low-salt diet is considered important for control of ascites in cirrhotic patients. To validate whether the spot urine sodium (Na)/potassium (K) ratio could replace 24-h urine Na (uNa) excretion in assessing low-salt diet compliance.

Methods
We prospectively studied 175 patients. 24-h urine collection and spot urine collection were performed. Subsequently, 24-h uNa, urine creatinine (uCr), and spot urine Na and K were assessed. A complete urine collection was confirmed based on 24-h uCr excretion levels of 15mg/kg/day for men and 10mg/kg/day for women. The area under the receiver operating characteristic (AUROC) curve analysis was performed to evaluate the feasibility of spot urine Na/K ratio in predicting 24-h uNa greater than 78mmol/day.

Results
Out of 175 patients, 24-h urine samples were completely collected in 57 patients only. Moreover, urine samples were not completely collected in 118 patients because their 24-h uCr excretion level was less than the established criteria. In complete urine collection group, AUROC curve for spot urine Na/K ratio in predicting 24-h uNa greater than 78mmol/day was 0.874±0.051 (P<0.001). In the incomplete urine collection group, the AUROC was 0.832±0.039 (P<0.001). In complete urine collection group, the classical cutoff value greater than 1.0 of spot urine Na/K ratio showed 90.9% sensitivity and 56.0% specificity.

Conclusions
The spot urine Na/K ratio reflects 24-h uNa, but the AUROC value obtained in this study is lower than that of a previous study. Considered the large number of patients with incomplete urine collection, validating 24-h complete urine collection criteria is necessary.
Role of educational programs in management of patients with medication-overuse headache
Authors: Shagbazyan A. E. , Kovalchuk N. A. , Tabeeva G. R. 
Published: June 2021

Patients with primary headaches are prone to frequent uncontrolled use of analgesics, leading to medication-overuse headache (MOH). One of the most accessible and effective strategies for its prevention is informing patients about the potential danger of its development. For this, training programs («schools») are conducted.Objective: to evaluate the effectiveness of educational programs in management of patients with MOH and its prevention.Patients and methods. We included 120 patients (12 men and 108 women, mean age: men – 46.3±3.54 years, women – 41.3±9.5 years) with primary headache and MOH. The follow-up period was 12 months. First, patients were divided into two groups depending on the clinical diagnosis: group I (n=44) – patients with chronic primary headaches without MOH, group II (n=76) – patients with chronic primary headaches and MOH. Then, patients in each group were randomized into subgroups depending on the prescribed therapy. All participants underwent repeated clinical examinations and questionnaires assessment at 1-, 3- and 12-months follow-ups. In addition, all patients kept a headache diary. An educational «school» developed for this study was held in those subgroups where educational programs were specified.Results and discussion. We observed a significant decrease in mean Headache-Attributed Lost Time (HALT) and Headache Impact Test (HIT-6) scores (р<0,05) at 12-months follow-up in subgroups where headache educational programs were combined with drug therapy, compared to the subgroups without educational programs. At the end of follow-up, we found a mean 1.75-fold increase in patients' treatment satisfaction (compared to baseline) in the subgroups where the «school» was held. Financial costs during the 12-month follow-up period for patients decreased by seven times because most patients stopped taking medications to relieve headaches.Conclusion. Information and educational programs are an integral part of the management of patients with MOH.
Profile and frequency of antiparkinsonian drugs adverse reactions: a systematic review and meta-analysis
Authors: Tappakhov A. A. , Popova T. E. , Vasilev A. I. , Govorova T. G. , Khabarova Yu. I. , Timofeeva K. A. , Schnaider N. A. 
Published: June 2021

Objective: to assess the predictors and prevalence of adverse drug reactions (ADRs) associated with antiparkinsonian drugs.Materials and methods. 18 clinical studies and randomized controlled trials were included in the analysis. We combined all registered ADRs for each drug and made direct comparisons with odds ratio (OR) and 95% confidence interval (95% CI) calculation.Results and discussion. Levodopa/benserazide (LB) had the best safety profile among levodopa drugs. Levodopa/carbidopa (LC) compared with LB was associated with more frequent development of nausea (OR=2.8; 95% CI: 1.51–5.21), aggravation of parkinsonism (OR=4.44; 95% CI: 2.12–9.28) and dizziness (OR=3.32; 95% CI: 1.5–7.33; p=0.002). Piribedil had the lowest number of ADRs among dopamine receptor agonists. Dizziness was more common with pramipexole and ropinirole than with levodopa (OR=1.82; 95% CI: 1.21–2.74 and OR=1.65; 95% CI: 1.11–2.44 respectively). Increased daytime sleepiness and peripheral edema have also been associated with pramipexole. Arterial hypertension was present in 9.6% of patients prescribed with piribedil. Amantadine compared with pramipexole was associated with a higher risk of hallucinations (OR=2.27; 95% CI: 1.24–4.12) and constipation (OR=2.40; 95% CI: 1.14–5.05). Patients prescribed with selegeline had higher odds of dizziness (OR=3.40; 95% CI: 1.76–6.55) and hallucinations (OR=4.30; 95% CI: 1.83–10.09) compared to rasagiline.Conclusion. Based on the results, we propose a diagram of the relationship between ADRs and their frequency with antiparkinsonian drugs. We hope that the study will find clinical application and allow neurologists to consider the effectiveness and the expected risks of ADRs in the treatment of PD.
Changing participation in web conferencing: the shared computer screen as an online sales interaction resource
Authors: Heinonen Pilvi , Niemi Jarkko , Kaski Timo 
Published: June 2021

Abstract
This article explores the increasing digitalization of workplace communication. Drawing on the material environment in a complex, technology-mediated workplace environment, the article investigates how remote sales interaction is constructed and managed by its participants. The data consist of web conferences conducted in Finland between a salesperson (SP) and a prospective customer (C). During the meeting, SP delivers a software solution demonstration on a shared computer screen on which only SP is able to take actions. Deploying the method of multimodal conversation analysis, the research focuses on how the shared computer screen is used as an interactional resource to achieve joint attention and to direct participants’ focus during the sales meeting. First, the shared screen view is SP’s resource; for instance, when SP describes the functionalities of the software, he/she recurrently uses deictic expressions and other linguistic means in combination with coordinated keyboard activity. Later, the shared screen view evolves into a medium for both participants’ actions. The findings suggest that, as the negotiation gets closer to the context of the customer organization’s business, C may use the screen as a vehicle for his/her own interactional purposes. Through a gradual growth in understanding of the software, C begins commenting on the screen view or guides SP’s actions on the shared screen, enabling both a collaborative sales interaction and knowledge construction in a complex technological environment. Unlike previous studies on technology-supported institutional telephone interactions, SP’s screen view in the present study is a resource shared by both the professional and the client. The study contributes both to the field of technology-mediated workplace studies as well as to the field of sales and marketing research.
Size-exclusion chromatography as a useful tool for the assessment of polymer quality and determination of macromolecular properties
Authors: Held Daniela , Kilz Peter 
Published: June 2021

Abstract
Polymers, macromolecules in nature and bio-polymers like proteins and antibodies are present in our every-day life and play an important role in our economy. They are obviously present as plastic products (e.g., containers, clothing, car tires) or components, e.g., as expedients in pharmaceutical formulations, additives in food and feed, stabilizers in cosmetics, used in construction materials, ceramics and are key in microchip production. Size-exclusion chromatography is the most important characterization technique for macromolecules. This review covers applications, instrumental setup, step-by-step guides for performing experiments and covers theoretical background as well as troubleshooting and tips and tricks.
Design and development of metamaterial bandpass filter for WLAN applications using circular split ring resonator
Authors: Revathi Gnanasekaran , Robinson Savarimuthu 
Published: June 2021

Abstract
In this paper, a metamaterial bandpass filter using Split Ring Resonators (SRR) is designed, analyzed, and developed for WLAN applications at 2.4 GHz frequency band. Here, metamaterial bandpass filters with and without Defected Ground Structure (DGS) are designed, analyzed and compared. The filter structure shows a considerable size reduction with 50% fractional bandwidth, quality factor of 2 and wide bandwidth. The simulation results of the proposed filters offered good insertion loss and return loss response. The filters have been modeled, fabricated and their performance has been evaluated using the Method Of Moment (MOM) based electromagnetic simulator IE3D. The dimensions of the proposed filter is 20 × 9 × 1.6 mm which is considerably reduced. The simulated and measured results projected that the proposed metamaterial filters are well suited for WLAN applications.
Supported on mesoporous silica nanospheres, molecularly imprinted polymer for selective adsorption of dichlorophen
Authors: Ma Yuxuan , Xu Yuan , Chen Hui , Guo Jifeng , Wei Xiao , Huang Lihui 
Published: June 2021

Abstract
The imprinted polymers were prepared to absorb dichlorophen (DCP) by using mesoporous silica with ordered pores and high specific surface area. Both scanning electron microscopy and transmission electron microscopy results suggested that the mesoporous silica nanosphere pores had a periodic distribution. The imprinted layer of polymers was thin and uniform. The adsorption experiments showed that the adsorption of imprinted polymers was obviously improved due to the presence of mesoporous structure. The maximum adsorption capacity of MSNs@MIPs at 318 K was 91.1 mg/g, and the adsorption process rapidly reached the equilibrium within 40 min. The adsorption isotherm was well fitted by the Freundlich isotherm model, indicating that multimolecular layer adsorption mechanism governs the adsorption of DCP by the polymers. The adsorption of MSNs@MIPs complied with pseudo-second-order kinetic model. Both selective and regenerative experiments demonstrated that MSNs@MIPs can be successfully applied for selective adsorption of DCP.
Real-time hardware emulation of wind turbine model with asynchronous generator under hardware-in-the-loop platform
Authors: Thomas Tomson , Asok Prince , Mattathil Radhakrishnan Anoopraj , Puthenpurayil Sunil Kumar P. R. 
Published: June 2021

Abstract
Renewable energy sources are becoming as one of the major generation strategies around the world. The wind energy systems have been technologically advanced and integrated to the power system in a rapid routine. This paper looks into the modelling as well as operational exploration of a three blade wind turbine connected to asynchronous generator. State-of-the-art wind turbine topologies and a comparative summary of real-time simulation technologies for electrical systems are described. A 2.4 MW wind turbine with three blades is modelled for the analysis of power characteristics. The shift from sub-synchronous to super-synchronous mode is analysed for type-A wind energy conversion system (WECS) with 2 MW asynchronous generator by using MATLAB/Simulink model. The step-by-step standard operating procedure for modelling and real-time simulation of 2 MW type-A WECS having asynchronous generator under hardware-in-the-loop platform is elucidated. The steady state and transient behaviours of the WECS are validated by the real-time emulation under a hardware-in-the-loop platform.
Frequency stability analysis with fuzzy adaptive selfish herd optimization based optimal sliding mode controller for microgrids
Authors: Jena Narendra Kumar , Sahoo Subhadra , Sahu Binod Kumar , Mohanty Kanungo Barada 
Published: June 2021

Abstract
This article articulates the frequency control in an isolated microgrid (MG) under a centralized secondary controller. The penetration of distributed generators (DGs) which are weather dependant, and some of them are inertia less cause the instability in the MG. Besides this, unusual/abrupt load change, communication delay, and parameter change uncertainties make the MG more unstable. So, to restore the stability of the MG a sliding mode controller (SMC) is employed. The design of the SMC is carried by selfish herd optimization (SHO) algorithm. To validate the performance of SHO-SMC controller, it is compared with the results obtained by GOA-FOPID-(1+PI), SHO-PID, SHO- FOPID, and SHO-FOPID-(1+PI) controllers. Further, to establish an ameliorated dynamic response of the MG, SHO is modified by applying fuzzy logic named as fuzzy adaptive SHO (FA-SHO). In addition to this, in a two area MG, the potential of SHO/FA-SHO SMC controllers over SHO-SMC, and SHO/FA-SHO FOPID-(1+PI) controllers has been examined. Finally, with some crucial intermittent uncertainties like abrupt load change, time delay, and parameter variation, the robustness of the proposed controller is established.
Residual stress and simulation of 304–430 stainless steel dissimilar laser-welded joints incorporating materials heterogeneity
Authors: Zhao Xilong , He Feng , Wang Kun 
Published: June 2021

AbstractAn Nd:YAG laser device is used to conduct laser welding for a 1 mm austenitic stainless steel plate and a ferritic stainless steel plate. A finite element model of the shear punching test is constructed to generate the maximum shear strength in the weld, and the finite element model of laser welding is created using the welding temperature field. The hole drilling test result and the residual stress generated by two algorithms (Nonuniform-material and uniform-material) are compared. Results show that a drop-off of residual stress in the central area of the welded joint is observed when materials heterogeneity is disregarded. When materials heterogeneity is considered, the residual stress curve indicates smooth transition. The value of the latter appears reasonably similar to the experimental value. Therefore, this solution is advantageous in terms of residual stress simulation in dissimilar welded joints and does not critically affect residual deformation.