bluuebunny/crossref_metadata_2025_split huggingface dataset:
Inhibition of inflammatory cell infiltration by antagonistic peptides that specifically bind to CCR5 via regulation of the NF-kappa B signaling pathway in rats with colitis
Authors: Song Yang-Da , Song Yi-Hang , Liu Si-Xue , Huang Hua-Rong , Zhong Yingqiang 
Published: May 2021

IntroductionCC chemokine receptor 5 (CCR5) and the NF-κB signaling pathway play important roles in the pathophysiology of inflammatory bowel disease (IBD). Previously, we synthesized two peptides (GH and HY peptides) that specifically bind to the first and the second extracellular loops (ECL1 and ECL2, respectively) of CCR5 and preliminarily found an inhibitory effect of these peptides on colitis. However, the specific mechanism by which these two peptides regulate trinitrobenzene sulfonic acid (TNBS)-induced colitis in rats remains unclear.Material and methodsExperimental colitis was induced by 5% TNBS. CCR5 antagonist peptides were administered intravenously once a day for a week. Histological evaluation, real-time PCR, western blotting and correlation analysis were performed to examine the effects of the CCR5 binding peptides on the infiltration of inflammatory cells and the NF-κB signaling pathway.ResultsGH and HY peptides ameliorated mucosal damage and reduced the infiltration of neutrophils, lymphocytes and macrophages in experimental colitis (P < 0.05). The expression of NF-κB-related genes, including p105, p100, IKK and TNF-α, was reduced after GH and HY peptide administration (P < 0.01), and the protein level of TNF-α and the phosphorylation of IKK, IκBα and p65 were also suppressed. Furthermore, CCR5 antagonist peptides inhibited nuclear translocation of p65. Spearman correlation analysis showed that the infiltration of inflammatory cells was significantly correlated with the NF-κB pathway.ConclusionsAntagonistic peptides that specifically bind to ECL1 and ECL2 of CCR5 inhibit the infiltration of neutrophils, lymphocytes and macrophages in the colonic mucosa of SD rats with TNBS-induced colitis via regulation of the NF-κB signaling pathway.
Big Five and Dark Triad personality traits as predictors of multicultural attitude and efficacy
Authors: Kayiş Ahmet , Akcaoğlu Mustafa 
Published: May 2021

BackgroundThe advances in communication and transportation facilities have accelerated the formation of multicultural societies worldwide. Personality traits may be one of the most important indicators of adapting to multicultural environments. Educational environ-ments are multicultural in terms of the composition of students they serve. The present study investigated the predictive role of Big Five and Dark Triad personality traits on multicultural attitude and efficacy (MAE) among teacher candidates.Participants and procedureThe study population comprised of teacher candidates (N = 404) studying in Turkey. In order to collect data, Big Five personali-ty and the Dark Triad, the Adjective Based Personality Scale and the Dark Triad Dirty Dozen Scale were used respectively. In addition, data regarding MAE were collected through the Multicultural Efficacy Scale.ResultsThe results showed that openness to new experience positively (β = .16, p < .01) and psychopathy negatively (β = –.16, p < .01) predicted multicultural attitude. On the other hand, multicultural efficacy was positively predicted only by openness to new experience (β = .32, p < .001). Therefore, openness and psychopathic traits can play an important role in explaining multi-cultural attitude and efficacy. Also, there is no significant difference with regard to teacher candidates’ multicultural efficacy and attitudes according to their grade level.ConclusionsIndividuals with openness to new experiences personality trait have a positive attitude towards multiculturalism, and they view themselves as competent to get involved in multicultural environments. On the other hand, individuals with the psychopathy personality trait have negative attitudes towards multiculturalism.
Changing the type of knowledge of results affects the learning of a line-drawing task
Authors: M. Fisher Kevin , Kartes Weston , Gregorski Megan 
Published: May 2021

PurposeAugmented feedback is information that is inherently unavailable to a learner and must be provided by an outside source such as an expert or technical display. Such feedback may be divided into knowledge of performance, relating to movement quality, and knowledge of results (KR), relating to a movement outcome. KR has been examined with respect to variables such as timing, medium, and precision. In previous research involving a line-drawing task, individuals presented with higher levels of KR precision outperformed those presented with distracting feedback (nonsense syllables) or none. The present study sought to extend these findings by comparing the effects of KR types on learning a line-drawing task.MethodsOn day 1, participants (n = 48) practised in 4 groups, receiving unique extrinsic feedback: control (no feedback), vague, precise, and visual feedback group. On day 2, learning was assessed via retention and transfer testing.ResultsFor acquisition, a repeated-measures ANOVA revealed a main effect for block in absolute constant error and variable error (<i>p</i> < 0.01), indicating improved accuracy and consistency with practice. During testing, results showed a main effect such that accuracy and consistency during retention were better than transfer (<i>p</i> < 0.01). Follow-up pairwise comparisons indicated significantly better performance for the visual feedback group when compared with the control group (<i>p</i> = 0.021).ConclusionsThese results suggest that learning a simple task such as line-drawing may improve through verbal or visual feedback and that the latter medium may be an effective alternative to feedback that is presented verbally.
Time perspective, future anxiety, and hope for success in individuals awaiting bariatric surgery
Authors: Tucholska Kinga , Gulla Bożena , Grabowska Anna , Major Piotr 
Published: May 2021

BackgroundThe paper focuses on the problems of temporal functioning of obese individuals and of individuals prepared for bariatric treatment. The experience of time heavily weighs on many areas of human functioning, everyday activity, planning and achieving goals, engaging in pro-health behaviours, and in consequence on the quality of life and on physical health. Contingent on numerous factors, obesity may be related to focusing on particular aspects of time perspective. The aim of the study was to determine the specificity of particular temporal dispo-sitions in individuals prepared for bariatric surgery, and thus to devise suitable post-op psychological interven-tions.Participants and procedureThe study sample comprised 28 individuals (60.7% women, mean age M = 43.82 years, SD = 10.01, mean BMI M = 44.83 kg/m<sup>2</sup>, SD = 6.51) awaiting bariatric surgery. The data were collected individually with the following pen-and-paper questionnaires: the Zimbardo Time Perspective Inventory, the Dark Future Scale, and the Polish adaptation of Snyder’s Adult Hope Scale, which is named the Hope for Success Questionnaire.ResultsThe results showed the prevalence of present hedonistic time perspective in the obese. With regard to future anxiety or the hope for success, no significant deviations from the general population were observed.ConclusionsThe results indicate that this group is in need of temporal psychotherapy aimed at balancing the time perspec-tive. The results may also be interpreted through the lens of contextual determinants connected with task orien-tation preceding the surgery.
Changes of narrative meaning-making markers
during the different phases of breast cancer
treatment for women below 50 years old
Authors: Luisa Martino Maria , Lemmo Daniela , Gargiulo Anna , Barberio Daniela , Abate Valentina , Avino Franca , Francesca Freda Maria 
Published: May 2021

IntroductionThe onset of breast cancer is considered a potential traumatic event associated with physical and psychological effects, in particular when it occurs at the age below 50. The literature lacks a longitudinal narrative exploration of breast cancer experience of young women.Participants and procedureUsing the narrative device as a diachronic tool aimed at promoting semiotic connection processes during the different phases of the therapeutic path, the authors constructed an ad hoc narrative interview to explore the meaning-making processes of 10 breast cancer patients below 50 years old during three turning-point phases: pre-hospitalization (T1); postoperative counseling (T2); and adjuvant therapy (T3). The research took place at National Cancer Institute Pascale of Naples. Through an ad hoc qualitative methodology, this study identifies the prevailing modes with which the five narrative meaning-making functions are articulated in the repeated narrative during the three phases.ResultsThe findings capture the patterns of change of narrative meaning-making markers during the illness experience, highlighting both integrated modes of connections between aspects of experience over time and moments of block in specific critical phases for women under 50.ConclusionsFrom a clinical health psychology point of view the results suggest the promotion of integration between the synchrony of the medical path and the diachrony of the subjective experience of women to support resources for adapting to experience.
Investigating the effectiveness of adding microcurrent therapy to a traditional treatment program in myofascial pain syndrome in terms of neck pain and function
Authors: H. Battecha Kadrya , M. Kamel Dalia , A. Tantawy Sayed 
Published: May 2021

IntroductionTo investigate the effect of microcurrent on pain, pain threshold, range of motion, neck muscle strength, and neck function.MethodsIt is a pilot study involving 28 female subjects (aged 18–24 years) complaining of neck pain due to active unilateral trigger points in upper trapezius muscle. The subjects were randomly assigned to 2 groups: group I (<i>n</i> = 15) received microcurrent (frequency: 20 Hz, intensity: 25–30 µA) and traditional treatment in the form of stretching exercise for upper fibre of trapezius, isometric strengthening exercise, ischaemic compression technique; group II (<i>n</i> = 13) received only traditional treatment. All subjects received 2 sessions per week for 3 weeks.ResultsThere was a significant improvement (<i>p</i> < 0.05) in cervical range of motion, pain level, neck disability index, and pain threshold in both treatment groups. Isometric muscle strength was significantly increased (<i>p</i> < 0.05) in group I, with no significant (<i>p</i> > 0.05) difference in group II. Group I showed a more significant effect in all measured variables than group II. Neck disability index and muscle strength presented a significant change (<i>p</i> < 0.05) with respect to group and time interaction.ConclusionsMicrocurrent therapy added to traditional treatment increased the effectiveness of myofascial pain syndrome treatment as compared with traditional treatment alone.
Laboratory study of the collection efficiency of submicron aerosol particles by cloud droplets – Part I: Influence of relative humidity
Authors: Dépée Alexis , Lemaitre Pascal , Gelain Thomas , Monier Marie , Flossmann Andrea 
Published: May 2021

Abstract. A new In-Cloud Aerosol Scavenging Experiment (In-CASE) has been conceived to
measure the collection efficiency (CE) of submicron aerosol particles by
cloud droplets. In this setup, droplets fall at their terminal velocity
through a 1 m high chamber in a laminar flow containing aerosol
particles. At the bottom of the In-CASE chamber, the droplet train is
separated from the aerosol particle flow – droplets are collected in an
impaction cup, whereas aerosol particles are deposited on a high-efficiency
particulate air (HEPA) filter. The collected droplets and the filter are
then analysed by fluorescence spectrometry since the aerosol particles are
atomised from a sodium fluorescein salt solution
(C20H10Na2O5). In-CASE fully controls all the parameters
which affect the CE – the droplets and aerosol particles size distributions
are monodispersed, the electric charges of droplets and aerosol particles
are controlled, and the relative humidity is indirectly set via the
chamber's temperature. This novel In-CASE setup is presented here as well as
the first measurements obtained to study the impact of relative humidity on
CE. For this purpose, droplets and particles are electrically neutralised. A
droplet radius of 49.6±1.3 µm has been considered for six
particle dry radii between 50 and 250 nm and three relative humidity levels
of 71.1±1.3 %, 82.4±1.4 % and 93.5±0.9 %. These new
CE measurements have been compared to theoretical models from literature
which adequately describe the relative humidity influence on the measured
CE.
Opportunities and risks of disaster data from social media: a systematic review of incident information
Authors: Wiegmann Matti , Kersten Jens , Senaratne Hansi , Potthast Martin , Klan Friederike , Stein Benno 
Published: May 2021

Abstract. Compiling and disseminating information about incidents and disasters are key to disaster management and relief. But due to inherent limitations of the acquisition process, the required information is often incomplete or missing altogether. To fill these gaps, citizen observations spread through social media are widely considered to be a promising source of relevant information, and many studies propose new methods to tap this resource. Yet, the overarching question of whether and under which circumstances social media can supply relevant information (both qualitatively and quantitatively) still remains unanswered. To shed some light on this question, we review 37 disaster and incident databases covering 27 incident types, compile a unified overview of the contained data and their collection processes, and identify the missing or incomplete information. The resulting data collection reveals six major use cases for social media analysis in incident data collection:
(1)
impact assessment and verification of model predictions,
(2)
narrative generation,
(3)
recruiting citizen volunteers,
(4)
supporting weakly institutionalized areas,
(5)
narrowing surveillance areas, and
(6)
reporting triggers for periodical surveillance.
Furthermore, we discuss the benefits and shortcomings of using social media data for closing information gaps related to incidents and disasters.
ANALISIS STANDAR MINIMAL PERGUDANGAN PADA LOGISTIK PEMILIHAN UMUM SERENTAK DI INDONESIA
Authors: Vikaliana Resista , Purnaya I Nyoman 
Published: May 2021

Tujuan Penelitian ini adalah untuk mengetahui standar minimal pergudangan logistik pemilu di daerah perkotaan. Penelitian ini bermanfaat dalam memberikan masukan pada Pemilu yang untuk pertama kali dilakukan serentak ini. Masukan tersebut diharapkan dapat meningkatkan efektifitas dalam penyaluran atau distribusi surat suara sehingga dapat menghasilkan surat suara dan perangkat lainnya yang yang baik, pada saat diperlukan oleh pihak-pihak yang terkait. Penelitian ini menggunakan pendekatan kualitatif dengan wawancara mendalam dengan key informan, observasi dan studi dokumentasi. Berdasarkan hasil penelitian, maka disimpulkan KPUD Kota Depok sudah memenuhi kriteria gudang yang baik sebagai gudang logistik pemilu, karena sudah memenuhi kriteria standar minimal gudang yang baik,Sehingga disarankan KPUD menggunakan kriteria gudang tersebut, untuk menjamin kualitas dan keamanan logistik pemilu. Kata kunci: logistik pemilu, pemilu serentak, standar gudang,
Hubungan Stres Kerja Terhadap Kinerja Karyawan Pada PT. Pasifik Satelit Nusantara Jakarta
Authors: Rosmiati Eros , Sova Maya , Ahmadun Ahmadun 
Published: May 2021

Penelitian ini bertujuan untuk mengetahui hubungan stres kerja terhadap kinerja karyawan di PT. Pasifik Satelit Nusantara Jakarta. Jumlah sampel dalam penelitian ini adalah 80 karyawan PT. Pasifik Satelit Nusantara Jakarta. Untuk menganalisis data digunakan adalah uji validitas, uji reliabilitas, uji asumsi Klasik, dan determinasi (r 2) dengan uji hipotesis adalah uji F dan uji t.Hasil penelitian adalah diketahuinya hubungan stres kerja dengan Fhitung (182,731) > Ftabel (3,96) dan tingkat signifikansi di bawah 0,05. Selain itu berdasarkan uji t, stres kerja pada kinerja karyawan, dimana stres kerja diperoleh nilai sig 5,884> 1,99 dan signifikan terhadap kinerja karyawan. Kata kunci: stres kerja, kinerja karyawan
Analisis Fundamental Terhadap Harga Saham Pada Perusahaan Tekstil Dan Garmen Yang Terdaftar Pada BEI
Authors: Brata Ismaya Sakti , Nuraini Ani , Baharudin Agus 
Published: May 2021

Penelitian ini bertujuan untuk mengetahui hasil analisis pengaruh fundamental yang terdiri dari CR, TATO, DER dan ROE terhadap harga saham pada perusahaan tekstil dan garmen yang terdaftar pada Bursa Efek Indonesia periode tahun 2014 – 2017. Penelitian ini untuk mengetahui hubungan antar variabel dengan menggunakan analisis regresi data panel dengan cross section berasal dari 12 perusahaan dan time series selama 4 tahun. Berdasarkan hasil uji Chow, uji Hausman dan uji Breusch Pagan model yang terpilih di antara Common Effect, Fixed Effect dan Random Effect adalah Random Effect yang terbaik. Hasil uji signifikan menunjukkan hanya variabel TATO yang mempunyai pengaruh signifikan dan positif terhadap harga saham.Kata Kunci : CR, TATO, DER, ROE, Harga Saham
Pengaruh Kepuasan Pelanggan dan Loyalitas Pelanggan Terhadap Word of Mouth (Studi Kasus di Cafe Come On Coffe Pomalaa)
Authors: Titing Andry Stepahnie , Wonua Almansyah Rundu 
Published: May 2021

Tujuan penelitian untuk mengetahui bagaimana pengaruh kepuasan pelanggan dan loyalitas pelanggan terhadap word of mouth Pelanggan Come On Coffee. Populasi dalam riset ini adalah pelanggan Come On Coffee. Pengambilan sampel pada riset ini dilakukan menggunakan kuesioner dengan menggunakan metode purposive sampling. Metode analisis data yang digunakan pada penelitian ini yaitu SEM (Structural Equation Model) dengan menggunakan SmartPLS. Hasil penelitian menujukkan bahwa kepuasan pelanggan dan loyalitas pelanggan berpengaruh positif dan signifikan terhadap word of mouth.. Kata Kunci: kepuasan pelanggan, loyalitas pelanggan, word of mouth, dan come on coffee
Pengaruh Motivasi Kerja Intrinsik, Lingkungan Kerja, Disiplin Kerja,Terhadap Kinerja Karyawan (Studi Kasus Pada KSP Credit Union Dharma Prima Kita)
Authors: Patas Godrikus S 
Published: May 2021

ABSTRAKKinerja sebagai hasil-hasil fungsi pekerjaan/kegiatan seseorang atau kelompok dalam suatu organisasi dalam priode waktu tertentu pada KSP Credit Union Dharma Prima Kita. Penelitian ini bertujuan untuk mengui pengaruh secara parsial motivasi kerja, lingkungan kerja dan disiplin kerja terhadap kinerja karyawan. Subjek penelitian ini adalah karyawan KSP Credit Union Dharma Prima Kita, dengan total 70 responden. Penelitian ini menggunakan pendekatan kuantitatif dengan teknik analisis data regresi linier berganda dan menggunakan program komputer SPSS for windows 25. Hasil penelitian ini menunjukkan bahwa motivasi kerja berpengaruh positif dan signifikan terhadap kinerja karyawan, lingkungan kerja berpengaruh positif dan signifikan terhadap kinerja karyawan, disiplin kerja berpengaruh positif dan signifikan terhadap kinerja karyawan dan secara simultan motivasi kerja, lingkungan kerja dan disiplin kerja berpengaruh positif dan signifikan terhadap kinerja karyawan.Kata Kunci: Motivasi kerja intrinsik, Lingkungan Kerja, Disiplin Kerja, Kinerja
Hubungan Aktivitas Olahraga, Dan Asupan Nutrisi Dengan Kejadian Disminore Pada Reamaja Putri Kelas VIII Di SMP Negeri 1 Rajapolah Kabupaten Tasikmalaya Provinsi Jawa Barat Tahun 2017
Authors: Cintiani Dita , Sangadji Ismail 
Published: May 2021

Latar belakang: Dismenore merupakan salah satu keluhan ginekologi yang paling umum pada wanita usia muda yang datang ke klinik atau dokter. Oleh karena hampir semua wanita mengalami sensasi tidak nyaman selama haid (mild discomfort during menstruation), atau nyeri menstruasi membuat wanita tersebut tidak bisa beraktivitas secara normal dan memerlukan (resep) obat atau medication (Wiknjosastro, 2005).Tujuan penelitian: Untuk mengetahui dan menganalisis hubungan antara aktivitas olahraga, dan asupan nutrisi dengan kejadian Dismenore Pada Remaja Puteri Kelas VIII di SMP Negeri 1 Rajapolah Tahun 2017.Jenis penelitian: Menggunakan penelitian kuantitatif dengan pendekatan “Cross Sectional” dan teknik pengambilan sampel menggunakan teknik total sampling yaitu seluruh siswi SMP Negeri 1 Rajapolah kelas VIII dengan jumlah 90 orang. Pengambilan data dilakukan pada bulan Februari tahun 2017. Pengambilan data menggunakan kuesioner.Hasil penelitian: Menunjukan kejadian dismenore pada remaja putri kelas VIII di SMP Negeri 1 Rajapolah Tahun 2017 diperoleh hasil bahwa sebagian besar remaja putri mengalami kejadian dismenore yaitu sebanyak 57 orang (63,3%). Dari analisa bivariat didapatkan hasil ada hubungan antara aktivitas olahraga dengan kejadian disminore secara statistik didapatkan nilai (p value = 0,000), ada hubungan antara asupan nutrisi dengan kejadian disminore secara statistik didapatkan nilai (p value = 0,026).Simpulan penelitian: kejadian disminore pada remaja putri dipengaruhi oleh aktivitas olahraga dan asupan nutrisi.Saran: Diharapkan bagi institusi pendidikan, hasil penelitian ini dapat dijadikan sebagai informasi dan dapat mengadakan penyuluhan tentang Kesehatan Reproduksi secara umum khususnya dismenore agar meningkatkan pengetahuan, sikap, dan perilaku para siswa tentang kesehatan reproduksi khususnya dismenore. Kepustakaan : 20 literatur (2005 – 2017)Kata Kunci : Aktivitas Olahraga, Asupan Nutrisi, Kejadian Dismenore
Pengaruh Media Tanam terhadap Pertumbuhan Tanaman Terong (Solanum melongena L.) Dengan Sistem Hidroponik
Authors: Fandi Ali Al , Muchtar Ruswadi , Notarianto Notarianto 
Published: May 2021

Tanaman terong (Solanum melongena L.) merupakan salah satu jenis sayuran yang digemari oleh masyarakat Indonesia karena memiliki banyak vitamin dan mineral yang dibutuhkan oleh tubuh. Kebutuhan akan terong terus meningkat seiring dengan bertambahnya jumlah penduduk, meningkatnya kebutuhan pangan, namun luas lahan yang cenderung menurun oleh karena itu perlu adanya upaya untuk meningkatkan hasil produksi tanaman terong. Salah satu penyebabnya adalah adanya alih fungsi lahan dari pertanian menjadi non pertanian. Karena menurunya luas lahan mengakibatkan jumlah produksi ikut menurun. Oleh karena itu, diperlukan suatu upaya meningkatkan produksi terong tersebut diarea yang memiliki lahan terbatas. Salah satu cara meningkatkan produksi dilahan terbatas adalah dengan menggunakan hidroponik yang menggunakan beberapa jenis media tanam. Tujuan penelitian ini adalah untuk mengetahui pengaruh media tanam terhadap pertumbuhan tanaman terong dengan sistem sistem hidroponik. Penelitian ini dilaksanakan di Rumah Kaca Fakultas Pertanian Universitas Respati Indonesia, pada bulan Februari sampai dengan bulan Juli 2020. Rancangan yang digunakan dalam penelitian ini adalah Rancangan Acak Lengkap (RAL) dengan satu faktor yaitu media tanam yang terdiri atas 4 perlakuan yaitu Serbuk Kayu, B Zeolit, C Arang Sekam, dan Cocopeat. Masing-masing dengan 5 ulangan. Variabel penelitian meliputi tinggi tanaman, jumlah daun, dan jumlah bunga. Hasil pengamatan pada tanaman berumur 49, 63, 77, 91, 105 dan 133 hst menunjukkan bahwa media tanam serbuk kayu menunjukkan pengaruh yang lebih baik terhadap tinggi tanaman, jumlah daun dan jumlah bunga dibandingkan dengan perlakuan media tanam lainnya. Namun, pembentukkan buah pada semua tanaman perlakuan tidak ada akibat adanya serangan penyakit Virus Mozaik Tobacco pada seluruh bagian bunga dengan intensitas sedang. Kata Kunci: Pertanian Perkotaan, Hidroponik, Media Tanam, Tanaman Terong