bluuebunny/crossref_metadata_2025_split huggingface dataset:
Biodegradable shape-memory polymers and composites
Authors: Alauzen Tanner , Ross Shaelyn , Madbouly Samy 
Published: April 2021

Abstract
Polymers have recently been making media headlines in various negative ways. To combat the negative view of those with no polymer experience, sustainable and biodegradable materials are constantly being researched. Shape-memory polymers, also known as SMPs, are a type of polymer material that is being extensively researched in the polymer industry. These SMPs can exhibit a change in shape because of an external stimulus. SMPs that are biodegradable or biocompatible are used extensively in medical applications. The use of biodegradable SMPs in the medical field has also led to research of the material in other applications. The following categories used to describe SMPs are discussed: net points, composition, stimulus, and shape-memory function. The addition of fillers or additives to the polymer matrix makes the SMP a polymer composite. Currently, biodegradable fillers are at the forefront of research because of the demand for sustainability. Common biodegradable fillers or fibers used in polymer composites are discussed in this chapter including Cordenka, hemp, and flax. Some other nonbiodegradable fillers commonly used in polymer composites are evaluated including clay, carbon nanotubes, bioactive glass, and Kevlar. The polymer and filler phase differences will be evaluated in this chapter. The recent advances in biodegradable shape-memory polymers and composites will provide a more positive perspective of the polymer industry and help to attain a more sustainable future.
Nanotechnology-based materials as emerging trends for dental applications
Authors: Barot Tejas , Rawtani Deepak , Kulkarni Pratik 
Published: April 2021

Abstract
Nanomaterials have unique and superior properties such as high surface area and nanoscale size, makes them highly advanced and vital for rapid diagnosis and beneficial in treatment of numerous diseases in health sector. Joint efforts from multiple disciplines have contributed to the developments of advanced nanomaterials and enabled their uses in dentistry. These advanced nanomaterials can give more promising results in diagnosis and treatment procedures compared to their conventional counterparts. This review outlines the nanomaterials available and used in dentistry and will further go into discussing the shapes and compositions of various nanomaterials relevant to dentistry. Incorporating nanoparticles in dental restorative materials can be useful for preventing and/or managing dental caries. Integrating the sciences of nanomaterials and biotechnology, nanomaterials could potentially be revolutionary in improving oral health by providing preventative and diagnostic measures; they could also have effects on repairing damaged dental tissue.
Mechanical model and contact properties of double row slewing ball bearing for wind turbine
Authors: Zhang Hongwei , Chen Shuguang , Dou Yantao , Fan Hengming , Wang Yanqin 
Published: April 2021

Abstract
In this paper, the mechanical models of large-scale double row slewing ball bearing considering combined loading conditions were presented based on the rigid rings and flexible rings, respectively. And the contact properties between the ball and raceway were studied. These workflows for the calculation were described and programmed by MATLAB. The load distributions of slewing bearing for 2MW wind turbine were presented. The results indicated that the load distribution with the ideal stiff assumption differs from the load distribution determined by taking into account the flexibility of rings. With flexible rings, the magnitude of contact force is less than that of the rigid rings. The influences of the initial contact angle, the coefficient of groove curvature radius, the clearance on maximum contact force were analyzed and some suggestions have been discussed. These parameters have significant effects on the load distribution. The maximum contact force decreases with coefficient of groove curvature radius decrease. A three dimensional finite element model of the slewing bearing is established and analyzed. The simulated results are compared with that of mechanical models.
Supramolecular solvent-based microextraction techniques for sampling and preconcentration of heavy metals: A review
Authors: Jalili Vahid , Zendehdel Rezvan , Barkhordari Abdullah 
Published: April 2021

Abstract
Even very low concentrations of heavy metal pollutants have adverse effects on the environment and on human health. Thus, determining even trace concentrations of heavy metals in various samples has attracted a lot of attention. The conventional analytical methods used for the sampling and analysis of heavy metals have some limitations, including the effects of the matrix and their high detection limits. Thus, various methods are used for the pretreatment and concentration of the target analytes, and these methods are time-consuming, expensive, and require the use of toxic solvents. In recent years, supramolecular solvent-based microextraction (SSME), a green analytical strategy, has been used to determine low concentrations of heavy metals in various matrices. This method has unique features such as high enrichment factor, short extraction time, and rapid analysis. In addition, it is cost effective because it consumes less chemical reagents than other methods. Also, it is ecofriendly, and it has good sensitivity and selectivity. Herein, we presented a comprehensive review of the application of the SSME technique for the analysis of heavy metals in water, food, and biological samples. Also, we have provided the distinctive properties of the SSME technique, discussed the challenges that lie ahead, and addressed the potential future trend.
SH-SY5Y-derived neurons: a human neuronal model system for investigating TAU sorting and neuronal subtype-specific TAU vulnerability
Authors: Bell Michael , Zempel Hans 
Published: April 2021

Abstract
The microtubule-associated protein (MAP) TAU is mainly sorted into the axon of healthy brain neurons. Somatodendritic missorting of TAU is a pathological hallmark of many neurodegenerative diseases, including Alzheimer’s disease (AD). Cause, consequence and (patho)physiological mechanisms of TAU sorting and missorting are understudied, in part also because of the lack of readily available human neuronal model systems. The human neuroblastoma cell line SH-SY5Y is widely used for studying TAU physiology and TAU-related pathology in AD and related tauopathies. SH-SY5Y cells can be differentiated into neuron-like cells (SH-SY5Y-derived neurons) using various substances. This review evaluates whether SH-SY5Y-derived neurons are a suitable model for (i) investigating intracellular TAU sorting in general, and (ii) with respect to neuron subtype-specific TAU vulnerability. (I) SH-SY5Y-derived neurons show pronounced axodendritic polarity, high levels of axonally localized TAU protein, expression of all six human brain isoforms and TAU phosphorylation similar to the human brain. As SH-SY5Y cells are highly proliferative and readily accessible for genetic engineering, stable transgene integration and leading-edge genome editing are feasible. (II) SH-SY5Y-derived neurons display features of subcortical neurons early affected in many tauopathies. This allows analyzing brain region-specific differences in TAU physiology, also in the context of differential vulnerability to TAU pathology. However, several limitations should be considered when using SH-SY5Y-derived neurons, e.g., the lack of clearly defined neuronal subtypes, or the difficulty of mimicking age-related tauopathy risk factors in vitro. In brief, this review discusses the suitability of SH-SY5Y-derived neurons for investigating TAU (mis)sorting mechanisms and neuron-specific TAU vulnerability in disease paradigms.
Texts: A Case Study of Joint Action
Authors: Gangopadhyay Nivedita , Pichler Alois 
Published: April 2021

AbstractOur linguistic communication often takes the form of creating texts. In this paper, we propose that creating texts or ‘texting’ is a form of joint action. We examine the nature and evolution of this joint action. We argue that creating texts ushers in a special type of joint action, which, while lacking some central features of normal, everyday joint actions such as spatio-temporal collocation of agency and embodiment, nonetheless results in an authentic, strong, and unique type of joint action agency. This special type of agency is already present in creating texts in general and is further augmented in creating texts through digital media. We propose that such a unique type of joint action agency has a transformative effect on the experience of our sense of agency and subjectivity. We conclude with the implications of the proposal for social cognition and social agency. The paper combines research in philosophy of mind with the emerging fields of digital humanities and text technology.
The role of schemas and scripts in pictorial narration
Authors: Ranta Michael 
Published: April 2021

AbstractThe theoretical debate on the nature of narrative has been mainly concerned with literary narratives, whereas forms of non-literary and especially pictorial narrativity have been somewhat neglected. In this paper, however, I shall discuss narrativity specifically with regard to pictorial objects in order to clarify how pictorial storytelling may be based on the activation of mentally stored action and scene schemas. Approaches from cognitive psychology, such as the work of Schank, Roger C. & Robert P. Abelson. 1977.Scripts, plans, goals and understanding. Hillsdale, NJ: Lawrence Erlbaum; Mandler, Jean Matter. 1984.Stories, scripts, and scenes: Aspects of schema theory. London/Hillsdale, NJ: Lawrence Erlbaum; Schank, Roger C. 1995.Tell me a story: Narrative and intelligence. Evanston, IL: Northwestern University Press, suggest that cognition crucially depends on the storage and retrieval ofaction scripts or schemata, that is, narrative structures, which may occur at various levels of abstraction. These schemas incorporate generalized knowledge about event sequences, such as the order in which specific events will take place; causal, enabling, or conventionalized relations between these events, and what kind of events occur in certain action sequences. There also arescene schemasthat are characterized by spatial rather than temporal relations. Further kinds of schemas seem also to play a decisive role. Drawing upon considerations from schema and script theory, I will focus on some concrete examples of pictorial narration, more specifically depictions of theAnnunciation of the Virgin Mary, where narrative schema structures become involved and, indeed, the comprehensibility of the pictures as such presuppose mental script representations.
NMR spectroscopy threshold signal-to-noise ratio
Authors: Kolar Petar , Blažok Lovro , Bojanjac Dario 
Published: April 2021

Abstract
Ever since noise was spotted and proven to cause problems for the transmission and detection of information through a communication channel, a standard procedure in the process of characterizing a detection system of the communication channel is to determine the level of the lowest detectable signal. In signal processing, this is usually done by determining the so-called threshold signal-to-noise ratio (SNR). This determination is especially important for the communication channels and systems that constantly operate with low-level signals. A good example of such a system is definitely the NMR spectroscopy system. However, to the authors’ knowledge, the threshold SNR value of NMR spectroscopy systems has not been determined yet. That is why the experts in the field of NMR spectroscopy were asked to assess, using an online questionnaire, which SNR level they considered to be the NMR threshold SNR level. Afterwards, the threshold value was calculated from the obtained data. Finally, it was compared to the existing rule of thumb and thus, a conclusion about its legitimacy was made. The described questionnaire is still available online (https://forms.gle/Y9hyDZ1v1iJoEbk27). This enables everyone to form their own opinion about the threshold SNR level, which the authors encourage the readers to do.
Classification of gear pitting damage using vibration measurements
Authors: Grzeszkowski Mateusz , Nowoisky Sebastian , Scholzen Philipp , Kappmeyer Gregor , Gühmann Clemens , Brimmers Jens , Brecher Christian 
Published: April 2021

Abstract
In future aero engines, a planetary gearbox is to be integrated between fan and turbine to increase the efficiency and bypass ratio. This gearbox has to be monitored during operation to detect possible gearbox faults such as gear wear or gear pitting at an early stage. This paper presents a method consisting of vibration measurement, sensor-dependent feature extraction and support-vector machine (SVM)-based classification of pitting for gear condition monitoring. Several gears were loaded with a constant torque on a standardized back-to-back test rig to provoke pitting, and the pitting amount was captured during the tests with a camera. Features are extracted from accelerometers and an acoustic emission sensor, and based on the results of the visually recorded pitting surface, SVM classification is applied to identify the pitting defect. In this contribution, two different SVM classification approaches are investigated. One approach uses a Two-Class SVM, where tests from one gearset are used for SVM training and another approach utilizes a One-Class SVM based on outlier detection. Both methods show that single tooth pitting defects with a relative pitting area of less than 1 % can be effectively identified, whereas the One-Class SVM method showed a higher pitting detection accuracy.
Simple mathematical models for controlling COVID-19 transmission through social distancing and community awareness
Authors: Elgazzar Ahmed S. 
Published: April 2021

Abstract
The novel COVID-19 pandemic is a current, major global health threat. Up till now, there is no fully approved pharmacological treatment or a vaccine. Also, its origin is still mysterious. In this study, simple mathematical models were employed to examine the dynamics of transmission and control of COVID-19 taking into consideration social distancing and community awareness. Both situations of homogeneous and nonhomogeneous population were considered. Based on the calculations, a sufficient degree of social distancing based on its reproductive ratio is found to be effective in controlling COVID-19, even in the absence of a vaccine. With a vaccine, social distancing minimizes the sufficient vaccination rate to control the disease. Community awareness also has a great impact in eradicating the virus transmission. The model is simulated on small-world networks and the role of social distancing in controlling the infection is explained.
The effect of anesthesia on the risk of postoperative myocardial injury in elderly patients with hip fracture: randomized controlled trial
Authors: Kuchyn Iurii , Tokar Ihor , Bielka Kateryna , Artemenko Valerii , Semenko Nataliia 
Published: April 2021

Hip fractures are a common pathology among patients older 50 years and cause disability, reduced duration and quality of life, even with adequate management and surgery. In the perioperative period, the most common complications leading to the death of patients are cardiovascular disease. about a hip fracture.
The aim of our study was to determine the safest method of anesthesia in the context of acute myocardial injury during hip fracture surgery. The objectives of the study were to determine the frequency of postoperative myocardial damage in patients with hip fractures; compare the frequency of MINS with different types of anesthesia: general anesthesia (GA), spinal anesthesia (SA) and compartment psoas block with sciatic nerve block.
Materials and methods. Randomized controlled trial was conducted from January 2018 to August 2019 in the medical center “Into-Sana” (Odessa, Ukraine). Patients with planned osteosynthesis of the proximal femur were randomized into 3 groups depending on the method of anesthesia: general anesthesia and postoperative systemic analgesia, spinal anesthesia and postoperative systemic analgesia, prolonged compartment psoas block with sciatic nerve block.
Results. The study involved 90 patients. Acute postoperative myocardial injury was diagnosed in 17.6 % of cases. Postoperative elevation of troponins was significantly more often diagnosed in groups of patients with spinal anesthesia and general anesthesia compared to the group in which the psoas block compartment was used in combination with the sciatic nerve block. None of the patients had symptoms of myocardial ischemia and were not diagnosed with myocardial infarction. Hypotension was significantly more common in group 2 spinal anesthesia (OR 9 95 % CI 1.9-47, p=0.004) There was a direct moderate association between the intraoperative hypotension and the development of postoperative myocardial injury (r = 0.5).
Conclusions. Prolonged compartment psoas block with sciatic nerve block intraoperatively is the safest method of anesthesia in the context of the development of postoperative myocardial injury. Intraoperative hypotension is associated with postoperative myocardial injury
State of social and psychological adaptation in patients with depressive disorders, taking into account the gender factor
Authors: Belov Oleksandr 
Published: April 2021

The aim: to establish the features of socio-psychological adaptation in patients with depressive disorders, taking into account age and gender factor.
Materials and methods. A clinical and psycho-diagnostic examination of 107 men and 138 women with depressive disorders using the method of diagnosis of socio-psychological adaptation of C. Rogers et R. F. Dymond was done.
Results. A low level of socio-psychological adaptation in patients with depressive disorders has been established. There is a tendency to deteriorate socio-psychological adaptation with age, the most pronounced in level of adaptability, emotional comfort, payroll, integrated indicators of adaptation, self-acceptance and emotional comfort in all patients, and in men also in maladaptation, self-acceptance, external control, and women – regarding internality. The rates of lying, acceptance of others and dominance in men and women were highest in the middle age group (30-44 years), and lowest – in the older (over 45 years); this trend is also found in men for internal control and an integrated indicator of acceptance of others, and in women – for the desire for dominance. Differences in the comparison of the older age group with the average were more significant than in the comparison of the younger group (up to 30 years) with the average.
Conclusions. Patients with depressive disorders are characterized by a low level of socio-psychological adaptation. In both men and women, the level of socio-psychological adaptation decreases with age, and in men this trend is more pronounced. The most significant deterioration in the state of socio-psychological adaptation in patients with depressive disorders occurs at the age of over 45 years; this trend is also more common in men
Prospects for the use of the method of intravesical hyperthermic chemotherapy in the treatment of patients with non-muscle invasive bladder cancer
Authors: Chystiakov Roman 
Published: April 2021

The aim: to compare disease-free survival time (DFS) in high-risk non-muscle-invasive bladder cancer patients treated with adjuvant hyperthermic intravesical chemotherapy and standard BCG therapy.
Materials and methods: patients were divided into 2 groups. Group 1 (control) included patients who received adjuvant therapy after TURB with BCG vaccine (BCG therapy group; n=50), group 2 (study group) included patients (HIVEC® therapy group; n=46 ), who received adjuvant intravesical chemotherapy using a Combat BRS HIVEC® device for local hyperthermia.
Results: median follow-up was 23 months (range 4 - 36). Tumor recurrence was reported in 19 patients receiving intravesical BCG therapy and in 8 patients receiving intravesical hyperthermic chemotherapy. The incidence of DFS in patients receiving chemohyperthermy was statistically higher than in patients receiving BCG therapy (log-rank test result: p=0.029).
Conclusions: The method of hyperthermic intravesical chemotherapy significantly increased the 2-year disease-free survival rate - 82.6 % versus 62 % BCG therapy group (p=0.025). Its use in the future will allow increasing the frequency of organ-preserving treatment of patients with primary and recurrent muscular-non-invasive bladder tumors
Myelin basic protein and its diagnostic value in HIV-infected individuals with 4th clinical stage and neuroinfections
Authors: Kozko Volodymyr , Hvozdetska-Shaar Maryna , Sokhan Anton , Yurko Kateryna , Solomennyk Ganna 
Published: April 2021

It was shown that in HIV-infected patients, pathomorphological changes in the white matter in the form of demyelinization are already observed in the early stages of the disease. The most studied marker of this process is myelin basic protein that can be detected in cerebrospinal fluid or serum immediately after acute myelin breakdown.
The aim. To assess the diagnostic value of myelin basic protein content in serum and cerebrospinal fluid of HIV-infected individuals with 4th clinical stage and central nervous system opportunistic infections.
Materials and methods. Using ELISA with diagnostic kit “MBP ELISA” (Ansh Labs, USA), we studied the myelin basic protein content in serum and cerebrospinal fluid of 53 HIV-infected patients with 4th clinical stage and central nervous system opportunistic infections depending on its etiology, the outcome of the diseases and according to Glasgow coma scale score. As well correlation analysis with some laboratory and clinical indicators was performed.
Results. We found significantly increased myelin basic protein content in both cerebrospinal fluid and serum of HIV-infected patients 4th clinical stage with central nervous system opportunistic infections compared to control (p˂0.01), which indicate the presence of active demyelinization in central nervous system. The highest cerebrospinal fluid myelin basic protein was registered in patients with an unfavourable outcome of the disease, as death or residual neurologic deficit, and patients with cerebral toxoplasmosis. The cerebrospinal fluid myelin basic protein had an association with the size of white matter lesions on magnetic resonance imaging and serum myelin basic protein content.
Conclusions. Myelin basic protein detection in cerebrospinal fluid as well as in serum can serve as an additional quantitative marker of myelin disruption, which can be used along with magnetic resonance imaging for the diagnosis improvement and prognosis of central nervous system opportunistic infections in HIV-infected individuals with 4th clinical stage