bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dermal extracellular matrix response to facetem implant: a randomised controlled experimental study
Authors: Mogilnaya Galina M. , Fomicheva Evgeniya V. 
Published: October 2021

Background. A leading concept in modern regenerative medicine is the perspective of using own body resources to remodel organs and tissues via the formation of “living scaffold”. A pivotal role in the formation of dermal scaffold is played by fibroblasts that produce extracellular matrix (ECM).Aim. A study of the fibroblast activation mechanism mediating synthesis of the dermal ECM fibrillar component under the Facetem filler administration.Methods. The experimental trial was conducted in Wistar male rats (72 animals). Animals had 0.05 mL Facetem (Korea) injections subdermally. The filler is a calcium-containing product featuring gradual degradation delivered through structural microspheric properties of the Lattice-pore technology. Biological material was sampled at weeks 1 and 2 of months 1, 2, 3 and 5. Tissues were paraffin-embedded in standard histological assays and stained with Mallory’s trichrome, Picrosirius red in polarisation microscopy and immunohistochemistry with collagen types I, III and elastin antibodies (Abcam).Results. Collagen distribution in dermis and the filling zone suggests that collagen production occurs by week 2 of the Facetem filler placement followed by an increase in synthesised matrix volume to 4.39 ± 0.7 for collagen type I and 3.9 ± 0.2 for collagen type III (p < 0.05). The synthetic activity of fi broblasts reduces by month 3, albeit with collagen production remaining above control even by the end of month 5. Elastin synthesis also initiates by week 2 of the filler injection in dermis and grows by month 3.Conclusion. The presence of Facetem filler triggers a foreign body inflammatory response in dermis. This multifactorial process initiates with protein adsorption proceeding to dermal cell recruitment and modulation of fibroblasts and macrophages. Activation of these cell types induces neocollagenesis entailing the extracellular matrix synthesis and expansion in dermis.
Regional features of the incidence of mental disorders in the population (on the example of the Irkutsk region): a retrospective study
Authors: Alekhin Igor N. , Apkhanova Nadezhda S. , Dushina Ekaterina V. , Prokopyeva Maria L. 
Published: October 2021

Background.Mental and behavioural disorders pose a pressing challenge in healthcare as pertaining to socially significant diseases. The significance is conditioned by high morbidity rates, including temporary and permanent disability, high fi nancial burden of medical care andregular social subsidy to target groups. According to the World Health Organisation, mental burden currently aggravates to entail serious social, human-rights and economic impact around the globe.Objectives.A study of regional dynamics of mental and behavioural morbidity in the Irkutsk Region over a seven-year period.Methods.A retrospective descriptive study used statistics data on primary and overall morbidity of definitely diagnosed mental and behavioural disorders (other than substance use disorders; F00–F09, F20–F99). The analysis of mental and behavioural illness incidence was based on statistical reports over the period of 2013–2019. The inclusion criterion was definite diagnosis of a mental and behavioural disorder (other than substance use disorder; F00–F09, F20–F99) in children, adolescents and adults. The main study indicators were the regional mental morbidity rate and prevalence, mental and behavioural morbidity rates among “dispensary care” and “medical counselling” outpatients, and primary morbidity rates by mental and behavioural nosology groups.Results.The article reports the regional traits of mental morbidity dynamics exhibiting a growing trend in Irkutsk Region. The morbidity traits of primary diagnoses have been analysed in dispensary care and medical counselling outpatients. Growing psychoneurologic visits are observed along with the institutional redirection of fi rst diagnoses towards decreasing the numbers of dispensary care vs. medical counselling outpatients. Thus, the structure of fi rst mental diagnoses changed towards prevailed medical counselling. Primary morbidity rate in male population is higher almost 1.5-fold in the study period. Primary morbidity elevated in both men and women. A primary morbidity analysis in different age cohorts reveals its growth in ages 0–14, 40–59 and >60 years.Conclusion.Our analyses reveal a lowering primary morbidity rate of mental disorders in outpatients taken for dispensary care, given the overall higher incidence. This may occur due to an institutional and instructional change in medical care provided to this patient category, including ineffective diagnosis, poor aid access and visit rate, statistical reporting design and possible changes in the criteria of taking for dispensary care. This fact requires improvements in the legal regulation of outpatient management of mental and behavioural illness at psychoneurologic institutions and the development of clear criteria of registering for dispensary care.
Finite element method in computer simulation for improved patient care in dentistry: A systematic review
Authors: Dyachenko Denis Yu. , Dyachenko Svetlana V. 
Published: October 2021

Background. The fi nite element method is gaining acknowledgment in Russia and other developed countries in a range of areas, including medicine. In stomatology, the method is applicable in research and implication of novel treatment and relevant material design.Objective. The review highlights usage of the fi nite element method in computer simulation to improve quality of patient dental care.Methods. The review analyses the state-of-the-art in current scientific literature. Records were mined in the PubMed and e-Library databases at a depth of 10 years, with selective inclusion of earlier articles. The query keywords were: finite element method [метод конечных элементов], computer simulation [компьютерная симуляция], quality of life improvement [повышение качества жизни], oral diseases [заболевания полости рта], dental treatment [стоматологическое лечение].Results. The review systematically surveys 56 scientific papers in the focus area for current state-of-the-art in the finite element analysis-empowered simulation in dentistry. The method’s rising employment is conditioned by its flexibility, 3D-object modelling simplicity and the rapid acquisition of reliable high-quality output. Its undoubted paramount advantage in dentistry is an explicit software visualisation of reliable results through co-modelling of multiple oral parameters.Conclusion. The growing acquaintance, mastering and use of this technique among researchers around the globe will give impetus to novel diagnosis and treatment, as well as relevant management algorithms in particular patient categories to enable personalisation of even mass dental check-up. This will reduce the number of visits, peri- and posttreatment error and complication rates for the improved patient’s quality of life and social rehabilitation.
The relationship of creative leadership with crisis management for the secondary stage in public schools in Jeddah from the teachers' point of view: علاقة القيادة الإبداعية بإدارة الأزمات للمرحلة الثانوية في المدارس الحكومية بمدينة جدة من وِجهة نَظر المعلِّمات
Authors: Hanaa Ebrahim Semran Al-Juhani, Randa Hariri Hanaa Ebrahim Semran Al-Juhani, Randa Hariri 
Published: October 2021

The study aimed to discover the relationship between practicing creative leadership and school management crisis among female educational leaders of publicsecondary schools in Jeddah from the latter’s’ perspectives. The study adopted adescriptive, correlational-relational research design and used a questionnaire to randomly collect data from a sample of (357) female teachers during the first semester of the 1441/1442AH academic year. Findings revealed that female school leaders practice creative leadership, and school crisis management at a high degree, whereby, accommodation and cooperation styles ranked first and second respectively, and avoidance style ranked last. Findings also showed that there were statistically significant differences at the level of (0.5 = α) between the means of the degree of creative leadership and crisis management practices referred to the difference in experience. Moreover, results showed a positive correlation between the degree of creative leadership and crises management practices. The study recommended holding events in the education and schools’ management that highlight the role of creative leadership and its impact on enhancing schools’ ability to manage and face crises, along with offering training courses aboutcrisis management, and encouraging relevant practices by teachers and staff members.
Assessment of Sleep Habits and Quality of Sleep among Elderly Residing in Rural Areas of Patiala: A Community-Based Cross-Sectional Survey
Authors: Yashika Kaushal  , Ratibha Kausal  , Isha Sharma  , Sheenab Mittal  
Published: October 2021

INTRODUCTION: Among the elderly, sleep problems are quite prevalent and can lead to many adverse health consequences. AIM: To assess the quality of sleep among the elderly residing in rural population and factors related to it, and provide necessary recommendations for its prevention. MATERIALS AND METHOD: In this cross-sectional study, elderly aged above 60 years residing in Patiala were taken and were interviewed separately using the modified version of the Pittsburgh Sleep Quality Index (PSQI), which was pre-tested and pre-validated prior to commencement of the study. Data recorded was divided into seven components and each component had an individual range of 0 (no difficulty) to 3 (severe difficulty) points and added to obtain a combined score of the individual with a range of 0(no difficulty)-21(severe difficulty) points. Based on the combined score, elderly obtaining a total score of 5 or greater was classified as having “poor sleep quality”. Statistics were applied using SPSS version 22.0, using the student’s t- test, and multivariate analysis. A p value < 0.05 was considered as significant. RESULTS: Out of 108 elderly people, most of the participants (62.9%) belonged to the age group of 60-75 years, out of which the majority (65.7%) were males. Most elderly reported having “fairly good” subjective sleep quality (53.7%, p=0.01) and was found to be significant with a global PQSI score of 7.22±4.31. Multivariate analysis revealed that significant “poor sleep quality” was observed in elderly aged above 75 years (OR:1.25, p=0.01) followed by elderly who were Immobilized (wheelchair/Bed ridden) (OR: 1.87, p=0.01). CONCLUSION: Efforts should be directed towards proper education of not only the elderly, but their children as well as colleagues and guardians to improve the sleep score of the elderly population.
The Importance of Telemedicine in a Post COVID World
Authors: Bhupesh Sharma  , Sanjana Manocha  , Nyagam Zangzom  
Published: October 2021

Telemedicine has found immense popularity, especially in a COVID-19 affected world. Its application shall improve the quality of health care provided to patients and help in time management as it help facilitates optimized referral systems which are based on the immediate/follow up needs of the patient, decision-making, reduction in patient’s waiting time as well as consultation time. This review is an effort to shed light on the main practical applications of teledentistry for emphasizing potentialities, problems, and applications of this relatively new branch in medicine. The paper also highlighted highlight the various aspects of telemedicine in relation to the healthcare sector, its advantages/disadvantages in a post COVID-19 world.
Career Planning and Career Management: Case on Workforce in Makassar
Authors: Tikson Shinta Dewi Sugiharti , Sahas Nadya Septiani , - Sri Ulfa , - Nurfadillah 
Published: October 2021

Every employee has a career goal he or she wants to achieve. In achieving his or her career, an employee will explore all available opportunities. Career planning is an effort made by individuals in setting goals or achieving desired career goals. This includes activities such as analyzing the abilities possessed, interest in work, values, to identify goals that need to be achieved in supporting the desired career. Looking at the current reality, many companies are experiencing changes caused by the coronavirus pandemic. This problem is felt not only by companies but also by employees because it can hinder their careers. This research is expected to provide insights on individual career planning and the role of organization in career management. This study shows there is a significant relationship between career planning and career management.
HORMONAL MANIFESTATIONS OF THYROID CANCER ASSOCIATED WITH AUTOIMMUNE THYROIDITIS
Authors: Sclifos Ina 
Published: October 2021

In medical practice, early diagnosis of CT is difficult because the neoplasm coexists or develops against the background of nodular-inflammatory thyroid pathologies, which have a slow evolution, CT is often associated with thyroiditis. The association of thyroid carcinoma with autoimmune thyroiditis remains debatable. In the literature, this combination is noted in 1% to 75% of cases. In recent years, there has been a steady increase in the number of thyroid cancers developed against the background of autoimmune thyroiditis, this being explained by improved diagnostic methods, living environment and increasing the number of elderly people. The relationship between inflammation and cancer is known to be that patients with autoimmune thyroiditis have a higher risk of developing thyroid cancer. The literature does not fully elucidate the hormonal peculiarities of thyroid cancer associated with autoimmune thyroiditis have not been studied yet in the Repulic Of Moldova
EFFECT OF DIFFERENT PROTEIN AND/OR METABOLIZABLE ENERGY LEVELS IN DIETS FORMULATED BASED ON IDEAL PROTEIN CONCEPT ON PERFORMANCE, EGG PRODUCTION, AND EGG QUALITY TRAITS OF LAYERS DURING PHASE 1 OF EGG PRODUCTION
Authors: Anwar Shaimaa R. , Al-Sagan Ahmed A. , R. A El- Bannaa , T. M Melegy 
Published: October 2021

A comparative study was conducted to determine the impacts of crude protein (CP) reductions in laying hen diets. During phase one of egg production, 270 laying hens were randomly assigned into six dietary treatments, which were replicated three times using a 2 × 3 factorial experiment. Reduced CP and metabolizable energy (ME) diets were formulated based on the ideal amino acid profile concept and supplemented with crystalline amino acids. The control treatment received standard commercial diets containing 18.8% CP and 2,725 kcal/kg ME. Average weight gain, hen day egg production percentage, egg weight, egg mass, and other selected egg quality parameters were recorded. Data were statistically analyzed. Feed consumption and the feed conversion ratio were improved in birds fed reduced CP diets supplemented with crystalline amino acids. The dietary CP level significantly influenced shell thickness (ST), while the dietary ME level had no effect. A highly significant interaction was observed between CP percent and the Haugh unit (HU). Results indicate that the “ideal protein concept” may be followed as an economically feasible option for laying hens since it optimizes the dietary amino acid profiles and ME levels, and have a positive effect on hen growth, egg quality and environmental pollution.
WHAT WILL HAPPEN TO NUMBER OF THE INFECTED IF ACCURACY OF THE PCR TEST IMPROVES?
Authors: Fujita Yasunori 
Published: October 2021

Among the strategies to tackle the COVID-19, much attention is paid to “test and isolation” advocated by Romer (2000), Peto et al (2020) etc., in addition to vaccination and development of medicines to treat COVID-19. According to these articles, what is necessary is a targeted version of lockdown, that is, to test everyone regularly and isolate the small fraction of the population who test positive.
There is, however, concern that the PCR test is not always effective, so that, in the present paper, we investigate the effects of improvement of the PCR test by constructing a simple intertemporal theoretical model. Main result we obtain is that improvement of the PCR test could increase the number of the infected individuals at first, so that we should improve the accuracy of the PCR test much enough to reduce the number of the infected individuals.
Media Sosial Dan Pembelajaran: Study Efektifitas Instagram dalam Pembelajaran Bahasa Inggris
Authors: Ni Made Lisma Martarini  , Kadek Ayu Riska Yulianti  , Ni Nyoman Ayu J. Sastaparamitha  
Published: October 2021

pilih. English for Spesific Purposes (ESP) adalah kemampuan Bahasa Inggris yang dikhususnya untuk tujuan tertentu. Writing skill adalah salah satu skill yang memiliki capaian kurang maksimal dilihat dari nilai hasil pembelajaran Mahasiswa STMIK-STIKOM Indonesia. Di era seperti sekarang ini dimana teknologi digital menjadi konsumsi dan kebutuhan vital dari masyarakat, media sosial adalah salah satu hal yang amat disukai para anak muda. Berangkat dari hal tersebut maka penelitian ini akan menggunakan media sosial kususnya Instagram sebagai media pembelajaran dan dapat memotivasi mahasiswa dalam belajar Bahasa Inggris. Teknik pengumpulan data yang digunakan adalah hasil tulisan baik pre-test maupun post-test, serta observasi, dan dokumentasi. Untuk mengetahui keefektifan media sosial Instagram sebagai sarana belajar akan dinilai dari hasil kuisioner dari mahasiswa. Sampel dari penelitian ini merupakan 30 mahasiswa jurusan Teknik Informatika, STMIK-STIKOM Indonesia. Tahapan dari proses pengambilan data dalam penelitian ini meliputi; (1) observasi kepada subjek penelitian ini, (2) tahap sosialisasi dengan mahasiswa tentang bagaimana tata cara pembelajaran dengan menggunakan media sosial ini khususnya dengan menggunakan Instagram, (3), pelaksanaannya penelitian ini, pada tahap ini mahasiswa akan diberikan materi pada awalnya dimana mereka tidak hanya menerima materi tersebut tetapi harus mencari materi pendukung lainnya, serta berdiskusi dan menerima saran serta masukan dari dosen maupun teman- temannya, (4)Tahapan terakhir adalah tahap pelaksanaan penggunaan Instagram sebagai sarana diskusi serta hasil.
Keefektifan Penggunaan Metode Clustering dan Show Not Tell terhadap Kemampuan Menulis Teks Deskripsi Peserta Didik SMP Kelas VII Di Kecamatan Binamu Kabupaten Jeneponto
Authors: Iskandar Iskandar 
Published: October 2021

Desain yang digunakan adalah one group pretest-posttest design, yaitu desain penelitian yang diberikan pre-test sebelum diberikan perlakuan dan pemberian post-test setelah diberikan perlakuan atau tindakan. Populasi dalam penelitian ini adalah SMP Negeri se-Kecamatan Binamu yang berjumlah 9 sekolah. Sampel dalam penelitian ini sebanyak 3 kelas pada tiga sekolah dengan jumlah 75 peserta didik. Penarikan sampel dilakukan dengan cara random cluster sampling. Dalam penelitian ini yang menjadi sampel adalah SMP Negeri 9 Binamu sebanyak 33 peserta didik, 27 Peserta didik di SMPN 6 Binamu, dan 25 Peserta didik di SMPN 4 Binamu. Jadi, jumlah keseluruhan peserta didik pada 3 sekolah sebanyak 75 peserta didik.Data yang diperoleh dianalisis dengan statistik deskriptif kuantitatif dan statistik inferensial. Berdasarkan analisis statistik deskriptif kuantitiatif menunjukkan bahwa penggunaan metode clustering dan Show Not Tell efektif dalam pembelajaran menulis teks deskripsi peserta didik SMP kelas VII di Kecamatan Binamu. Hal ini dibuktikan berdasarkan perolehan nilai rata-rata peserta didik pada pre-test 35,62. Selanjutnya, nilai post-test diperoleh nilai rata-rata sebesar 72,24 dengan jumlah sampel sama dengan pretest sebanyak 75. Berdasarkan data statistik tersebut menunjukkan bahwa terjadi peningkatan nilai rata-rata hasil penilaian menulis peserta didik berdasarkan nilai pre-test dan nilai post-test. Hasil analisis inferensial menggunakan uji t model paired sampel test tampak bahwa penggunaan metode clustering dan Show Not Tell efektif diterapkan dalam pembelajran menulis teks deskripsi pada peserta didik SMP kelas VII di Kecamatan Binamu. Hal ini berdasarkan hasil diperoleh nilai Sig. (2 tailed) sebesar 0,000 < 0,05. Ini menunjukkan bahwa terdapat perbedaan yang nyata hasil penilaian menulis teks deskripsi sebelum (pre-test) dan setelah (post-test) menggunakan metode Clustering dan Show Not Tell.
Pola Penggunaan Sapaan Bahasa Bima
Authors: Hasan Hasan 
Published: October 2021

Artikel ini merupakan hasil penelitian yang dilakukan di Lembaga Penelitian Universitas Hasanuddin. Permasalahan yang diteliti adalah bagaimana pola-pola penggunaan sapaan dalam bahasa Bima.Tujuannya adalah mencari dan menemukan variasi pola penggunaan sapaan dalam bahasa Bima. Pengumpulan data dilakukan melalui penelitian lapangan atau kerja medan dengan teknik: (1) observasi (pengamatan), (2) wawancara, (3) rekaman, (4) catat, (5) pilah. Data dianalisis dengan metode deskriptif kualitatif. Hasil penelitian menunjukkan bahwa, variasi jenis dan pola penggunaan sapaan bahasa Bima dapat diklasifikan sebagai berikut: (1) sapaan kata ganti diri, yang terdiri atas: (a) sapaan persona pertama (tunggal dan jamak), (b) sapaan persona kedua (tunggal dan jamak), (c) sapaan persona ketiga (tunggal dan jamak); (2) sapaaan nama diri, yang terdiri atas: (a) menyapa dengan nama diri asli (nama yang sebenarnya), (b) menyapa dengan nama diri secara sopan (penghormatan); (3) menyapa secara keakraban; (4) sapaan berupa jabatan dan gelar, yang terdiri atas: (a) sapaan berupa jabatan, (b) sapaan berupa gelar, (c) sapaan berupa gelar khusus, (d) sapaan gelar khusus dengan nama diri + kata sifat.
Peningkatan Keterampilan Menyusun Teks Eksplanasi dengan Model Investigasi Kelompok dan Media Visual pada Siswa Kelas VIII SMPN 21 Kota Makassar
Authors: Akram Budiman Yusuf  , Muhammadd Dahlan  
Published: October 2021

Tujuan penelitian ini adalah untuk meningkatkan keterampilan menulis teks ekplanasi melalui penerapan model Investigasi kelompok dan menggunakan media visual. Metode penelitian yang digunakan adalah kuantitatif dan deskripsi kualitatif. Pada studi awal, penelitian ini melibatkan mitra kerjasama guru Bahasa Indonesia SMPN 21 Kota Makassar untuk mendapatkan informasi terkait kondisi pembelajaran Bahasa Indonesia pada aspek keterampilan menulis teks eksplanasi dan tempat penelitian dalam menerapkan model Investigasi kelompok dan penggunakan media visual.
Penelitian ini merupakan penelitian tindakan kelas (PTK) yang meliputi dua siklus, yaitu siklus I dan siklus II dengan batas ketuntasan minimal 75. Siklus terdiri atas tahap perencanaan, tindakan, observasi, dan refleksi. Subjek penelitian ini adalah keterampilan menyusun teks eksplanasi pada peserta didik kelas VIII SMPN 21 Kota Makassar. Pengumpulan data dilakukan dengan wawancara observasi dan dokumentasi. Analisis data dilakukan menggunakan teknik kuantitatif.
Hasil penelitian ini menunjukkan proses pembelajaran keterampilan menyusun teks eksplanasi dengan model investigasi kelompok dan media visual pada siswa kelas VIII SMPN 21 Kota Makassar dari siklus I ke siklus II yaitu dengan rerata persentase 9.99% menjadi 91.67% dan mengalami peningkatan sebesar 91.67%.