bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of alloying systems on the properties of single crystal nickel-based superalloys
Authors: Glotka Alexander , Ol’shanetskii Vadim 
Published: October 2021

AbstractThe purpose of the investigation was to obtain the predictive regression models that help correct the calculation of the mechanical properties of single crystal nickel-based superalloys without conducting prior experiments. The paper considers the influence of alloying elements on their tendency to form phases in foundry nickel-based superalloys. Using the elements influence on the phase formation, the coefficientKc’ of the ratio of alloying elements for this class of alloys was set for the first time. We have revealed the short correlation of the ratioKc’ with the dimensional misfit of γ and γ’ crystal lattices. Also, a high probability to predict the misfit for multicomponent nickel systems is shown, which significantly affected the strength properties. The regression models of correlation dependencies on the dimensional γ/γ’- misfit were offered to predict the short-term and long-term limits of the strength of alloys. We determined the operating temperature at which the misfit value should decrease to zero. The structure stability should increase because of the structural stresses minimizing. This has a positive effect on strength and plastic properties.
Treatment of osteoporosis with teriparatide: The Slovenian experience
Authors: Kocjan Tomaz , Sabati Rajic Antonela , Jensterle Sever Mojca , Janez Andrej , Vidmar Gaj , Orehek Nina , Marc Janja , Ostanek Barbara 
Published: October 2021

Abstract
The aim of this study was to investigate the characteristics of postmenopausal women prescribed with teriparatide in Slovenia, during the first decade after its approval, and the predictors of bone mineral density (BMD) improvement with treatment. We retrospectively studied postmenopausal osteoporotic patients prescribed with teriparatide at tertiary center from 2006 to 2015. BMD was measured at standard sites by DXA at baseline, after 12 and 24 months. 25-hydroxyvitamin D and procollagen type I N-terminal propeptide (PINP) were measured at the same time-points. The inclusion criteria were met by 188 women (aged 71 years on average), 151 (80.3%) with postmenopausal and 37 (19.7%) with glucocorticoid-induced osteoporosis. Everyone had at least one fracture, 159 (84.6%) had ≥2 fractures, with vertebral fractures in 172 patients (91.5%). All patients had been previously on antiresorptives for 8.6 years on average. The average BMD change at lumbar spine, total hip, and femoral neck was +5.0%, −1.1%, and +0.3% after 24 months of treatment, respectively. Higher baseline PINP was associated with higher BMD increase at all sites after the first 12 months. Teriparatide was prescribed mostly to elderly women with severe osteoporosis who had sustained two or more fractures despite long-term antiresorptive therapy. Baseline PINP might predict initial BMD increase with teriparatide.
Moving Beyond the Individualist Paradigm? Risse and Wollner on Non-agential Exploitation
Authors: Heðinsdóttir Katla 
Published: October 2021

Abstract
Most philosophical examinations of the concept of exploitation center on analyzing two-party interactions between individuals. Mathias Risse and Gabriel Wollner introduce an account of exploitation that seeks to transcend this ‘individualist paradigm’ in three ways: Through exploitation of and by agential groups (non-individual exploitation), of or by non-agential groups (non-agential exploitation) and by social structures (structural exploitation). In this paper, I argue that while the concepts of non-individual and structural exploitation do offer each their way of transcending or revising the individualist paradigm, the most ambitious and original attempt to break with the paradigm is offered by the concept of non-agential exploitation. I then discuss this concept, but ultimately conclude that it suffers from too many shortcomings in its current form to offer a plausible departure from the individualist approach.
Transparent hybrid anapole metasurfaces with negligible electromagnetic coupling for phase engineering
Authors: Kuznetsov Alexey V. , Canós Valero Adrià , Tarkhov Mikhail , Bobrovs Vjaceslavs , Redka Dmitrii , Shalin Alexander S. 
Published: October 2021

AbstractAll-dielectric nanophotonics has become one of the most active fields of research in modern optics, largely due to the opportunities offered by the simultaneous resonant control of electric and magnetic components of light at the nanoscale. In this rapidly evolving scenario, the possibility to design artificial Huygens sources by overlapping electric and magnetic resonances has established a new paradigm in flat optics, bringing devices closer to efficient wavefront shaping with direct phase engineering at the level of the individual meta-atoms. However, their efficiency is fundamentally limited by the near-field coupling between the constituents of the metalattice. In this work, we challenge this well-conceived notion and propose an alternative concept to achieve phase control and full transmission in metasurfaces, based on the unusual properties of the nonradiating sources known as hybrid anapoles (HAs). We analyze theoretically an array of such sources and demonstrate that HAs are characterized by negligible coupling with their neighbors. Therefore, in contrast to Huygens particles, the proposed sources can operate as individual meta-atoms even in highly compact designs, becoming robust against strong disorder and preserving its characteristics when deposited on dielectric substrates. Remarkably, the phase of the transmitted wave can be modulated with negligible reflection. To illustrate the capabilities of our platform, we also utilize a disordered HA array to implement a controlled phase modulation to an ultrafast Gaussian pulse. The results of our study represent a departure from the currently established designs and open an avenue toward the realization of new devices for flat optics with unprecedented efficiency.
CASIE – Computing affect and social intelligence for healthcare in an ethical and trustworthy manner
Authors: Vasiliu Laurentiu , Cortis Keith , McDermott Ross , Kerr Aphra , Peters Arne , Hesse Marc , Hagemeyer Jens , Belpaeme Tony , McDonald John , Villing Rudi , Mileo Alessandra , Caputo Annalina , Scriney Michael , Griffiths Sascha , Koumpis Adamantios , Davis Brian 
Published: October 2021

Abstract
This article explores the rapidly advancing innovation to endow robots with social intelligence capabilities in the form of multilingual and multimodal emotion recognition, and emotion-aware decision-making capabilities, for contextually appropriate robot behaviours and cooperative social human–robot interaction for the healthcare domain. The objective is to enable robots to become trustworthy and versatile social robots capable of having human-friendly and human assistive interactions, utilised to better assist human users’ needs by enabling the robot to sense, adapt, and respond appropriately to their requirements while taking into consideration their wider affective, motivational states, and behaviour. We propose an innovative approach to the difficult research challenge of endowing robots with social intelligence capabilities for human assistive interactions, going beyond the conventional robotic sense-think-act loop. We propose an architecture that addresses a wide range of social cooperation skills and features required for real human–robot social interaction, which includes language and vision analysis, dynamic emotional analysis (long-term affect and mood), semantic mapping to improve the robot’s knowledge of the local context, situational knowledge representation, and emotion-aware decision-making. Fundamental to this architecture is a normative ethical and social framework adapted to the specific challenges of robots engaging with caregivers and care-receivers.
Naturally occurring heterocyclic anticancer compounds
Authors: Misra Shashi Kiran , Pathak Kamla 
Published: October 2021

Abstract
Naturally occurring heterocyclic scaffolds are key ingredients for the development of various therapeutics employed for biomedical applications. Heterocyclic pharmacophores are widely disseminated and have been befallen in almost all categories of drugs for the alleviation of myriad ailments including diabetes, neurodegenerative, psychiatric, microbial infections, disastrous cancers etc. Countless fused heterocyclic anticancerous templates are reported to display antimetabolite, antioxidant, antiproliferative, cytostatic etc. pharmacological actions via targeting different signaling pathways (cell cycle, PI-3kinase/Akt, p53, caspase extrinsic pathway etc.), overexpressive receptors (EGRF, HER2, EGF, VEGF etc.) and physiological enzymes (topoisomerase I and II, cyclin dependent kinase etc.). A compiled description on various natural sources (plants, microbes, marine) containing anticancer agents comprising heterocyclic ring specified with presence of nitrogen (vincristine, vinblastine, indole-3-carbinol, meridianins, piperine, lamellarins etc.), oxygen (paclitaxel, halichondrin B, quercetin, myricetin, kaempferol etc.) and sulphur atoms (brugine, fucoidan, carrageenan etc.) are displayed here along with their molecular level cytotoxic action and therapeutic applications.
Trajectory planning of the nursing robot based on the center of gravity for aluminum alloy structure
Authors: Zhang Libo , Gao Hanjun , Xu Huichao , Song Jing 
Published: October 2021

AbstractIn this paper, the robot arm is manufactured to increase the structural strength and improve safety. The stability of the nursing robot in the process of carrying out the typical nursing task of holding patients was studied, and the influence of the center of gravity on the movement stability of the nursing robot was analyzed. The mathematical model of the stability of the robot is built by using the inverse kinematics solution of the robot. By studying the trajectory planning of a nursing robot under the condition of ZMP constraint, the robot can move safely and optimally along the prescribed trajectory between two working points. The simulation results show that the algorithm can significantly improve the work safety of the robot. In the experiment, four pressure sensors are used to measure the pressure of four wheels on the ground, the data are obtained and substituted into the expression of center of pressure (COP) method. The results show that the stability is in a reasonable moving area without any hidden danger, and its COP value is less than the stable qualitative boundary, which verifies the rationality and effectiveness of the optimal center of gravity stability planning algorithm.
Endoplasmic reticulum stress in leukocytes from phenylketonuric patients
Authors: Bardak Kadriye , Özer Işıl , Amanvermez Ramazan 
Published: October 2021

Abstract

Objectives
Phenylketonuria (PKU) is a proteinopathy due to the deficiency of phenylalanine hydroxylase (PAH) enzyme. The pathological elevation of phenylalanine (Phe) and its metabolites in PKU is linked to neurological hallmarks and mental disabilities. The aim of this study was to examine the hypothesis that high levels of Phe caused endoplasmic reticulum (ER) stress in PKU patients.

Methods
We primarily evaluated ER stress markers glucose-regulated protein78 (GRP78) and C/-EBP homologous protein (CHOP), and thiobarbituric acid-reactive substances (TBARS) as a biomarker of oxidative stress in leukocytes and correlated it with blood Phe values from patients with PKU. Patients in this study were selected from individuals who were diagnosed with PKU as a result of the national neonatal screening program and undergone treatment at our university hospital. The subjects were divided into four groups: healthy controls, patients with hyperphenylalaninemia (HPA), BH4-responsive patients with PKU and patients with classic PKU. GRP78, CHOP and TBARS levels were estimated in leukocytes isolated from whole blood of subjects, Phe and tyrosine levels were determined in plasma.

Results
The levels of Phe in BH4-responsive PKU and classic PKU groups were statistically higher as compared to healthy controls, and Phe levels were higher in classic PKU compared to HPA group. CHOP levels were elevated by 35.3% in BH4-responsive group compared to control. GRP78, CHOP and TBARS showed no statistical differences between control and patient groups. GRP78 was also negatively correlated with Phe levels.

Conclusions
These results suggested that blood Phe concentrations might not be associated to ER stress in white blood cells obtained from the PKU patient groups under treatment.
Theoretical investigations of hydrogen absorption in the A15 intermetallics Ti3Sb and Ti3Ir
Authors: Miller Gordon J. , Dissanayaka Mudiyanselage Ranuri S. , Xie Weiwei 
Published: October 2021

Abstract
Ti3Sb and Ti3Ir adopt the A15 (Cr3Si type) structure and are reported to incorporate hydrogen atoms to an extent, respectively, of Ti3SbH∼3 and Ti3IrH3.8. First-principles electronic structure calculations were performed to identify factors contributing to the difference in maximum hydrogen composition for these two intermetallic compounds. Relative energies and changes in energy densities of states and crystal orbital Hamilton populations upon H insertion in the intermetallic compounds were examined. In both compounds, hydrogen atoms are attracted to [Ti4] tetrahedral interstitial sites over any others. The natures of metal-hydrogen and metalloid-hydrogen bonding and the effects of hydrogen insertion on metal-metal and metal-metalloid bonding have an influence on the maximum hydrogen contents for Ti3Sb and Ti3Ir.
Quantifying Change of Direction Movement Demands in Professional Tennis Matchplay: An Analysis From the Australian Open Grand Slam
Authors: Giles Brandon , Peeling Peter , Reid Machar 
Published: October 2021

ABSTRACT
Giles, B, Peeling, P, and Reid, M. Quantifying change of direction movement demands in professional tennis matchplay: An analysis from the Australian Open Grand Slam. J Strength Cond Res 37(7): 1419–1427, 2023—Change of direction (COD) contributes significantly to the movement repertoire of professional tennis players, yet the time-motion and degree demands of these changes are poorly understood. This study examines the velocity, acceleration, and angular displacement profiles of COD movements in modern professional tennis. One hundred eighty-two singles matches of Hawk-Eye player tracking data collected from the Australian Open Grand Slam were used for analysis. A novel COD classification algorithm was used to identify >120,000 medium and high-intensity CODs for analysis. Descriptive characteristics of the COD performance were calculated using player coordinate and time variables. Sex comparisons were analyzed using 2 mixed-effects models assessed for differences via likelihood ratios. Players performed 1.6 CODs per point. Both sexes executed, on average, 1.3–1.4 shots and covered 4.8 m per COD, with men performing changes every 2.7 seconds and women every 3.1 seconds. Medium-intensity COD comprised 88–94% of all identified changes. Approximately 2 in 3 CODs involved a degree of change >105°, whereas cutting maneuvers (<45°) were most commonly high-intensity COD. This study is the first to quantify the COD characteristics of professional tennis matchplay. Both sexes performed the same average number of CODs per point, however, men executed high-intensity changes twice as frequently as women, at an average of 1 every 5 points. These novel findings will help to improve the specificity of training interventions in elite tennis conditioning.
PENGARUH JUMLAH PENGHASILAN MARGIN PEMBIAYAAN MURABAHAH DAN ISTISHNA TERHADAP LABA PERUSAHAAN PERBANKAN DI INDONESIA
Authors: Khairunnisa Nurba Ash 
Published: October 2021

The purpose of this studdy wasto deetermine theeffect off murabahah dan istisna financing margin income simultaneously on the profits of Islamic bank companies in Indonesia. The miethod useed iis descriiptive methiod. The typ of researc date uses quantitative data types. Sources of research data used in this study are secondary data sources obtained from the financial statements of PT. Bank Muamalat Indonesia originating from www.bi.go.id. Analysiis ofi the date used is descriptive analysis, simple regression analysis and multiple linear regression using the te teist dan fi est wiiith ia quantitative approach that uses secondary data types in the form of quarterly financial statements published by PT.Bank Muamalat Indonesia for the 2014-2016 period. The analysis techniqueused is descriptive analysis, multipli linearegression analyisis, multiplie regresion analysiys, simple correlation analysis, multiple correlation analysis, determination analysis, t test analysis and F tes for data proocessing used SPSS Windows 16.00 and MiccrosoftExcel 2010 as a tool. . The results of the three variables research are:(1) murabahah margin income is obtained ttable> tcount (1,158> -0,331) meaning thiat theire iis a negative and insignificant influience beitween murrabahah margiin iincome oon company profits. (2) Istishna MarginRevenues 'obtained by the value ttable> tcount (1.158> 0.315) means thait theire iis no siignificant positive efect betwieen istisna margin earnings' ons company profits. (3) Murabahah and istishna margin income 'obtained by the value of Ftable> Fcalculation (0,2,228> 0,91) means that there is an insignificant positive effect between murabahah and istishna margin income' on company profits.
SINTESIS ZEOLIT CHABAZITE DENGAN RASIO Si/Al TINGGI TANPA MENGGUNAKAN SENYAWA ORGANIK
Authors: Kadir Iftitah Rahmi 
Published: October 2021

Zeolit tipe Chabazite (CHA) merupakan material bermikropori dengan 8 saluran cincin yang memiliki potensi besar untuk diaplikasikan sebagai katalis pada reaksi MTO (Methanol to Olefins. Umumnya zeolite tipe CHA dengan kadar silika tinggi bersifat hidrofobik dan disintesis menggunakan bantuan senyawa organik N,N,N-Trimethyl-1-adamanammonium hydroxide (TMAdaOH) sebagai pengarah struktur (Structure Directing Agent, SDA). Akan tetapi penggunaan SDA terutama TMAdaOH sangat tidak ekonomis dan tidak ramah bagi lingkungan. Untuk membuka pori zeolit, senyawa organik ini harus dihilangkan dengan pembakaran suhu tinggi. Pada tahap awal penelitian ini, CHA disintesis melalui transformasi interzeolit FAU (Faujasite) menjadi CHA, namun produk yang dihasilkan memiliki kadar silika rendah (Si/Al = 2), sehingga kami merancang proses sintesis CHA baru tanpa SDA dengan mereaksikan kembali produk CHA hasil inter-transformasi dengan penambahan sumber silika, alumina, NaOH, dan KOH. Metode hidrotermal diterapkan pada campuran ini dengan menggunakan suhu 170 oC selama 24 jam. Variasi komposisi molar Na2O dan K2O dengan kisaran 0.1 hingga 0.4 dilakukan untuk mempelajari pegaruh sinergis Na+ dan K+ terhadap kristalisasi zeolit tipe CHA dengan rasio Si/Al tinggi. Hasil analisis difraksi sinar-X (XRD) menunjukan zeolit tipe CHA dapat dihasilkan kembali dan fluorosensi sinar-X (XRF) menunjukan produk ini mempunyai rasio Si/Al=4 dari perbandingan Na2O dan K2O berturut-turut adalah 0,3 dan 0,1. Selanjutnya citra mikroskop pemindai electron (SEM) memperlihatkan morfologi dan ukuran partikel produk yang sama dengan morfologi dan ukuran kristal CHA hasil inter-transformasi.
ANALYSIS OF DEBT SHORT TERM AND RECEIVABLE TURNOVER ON THE PROFITABILITY OF MANUFACTURING COMPANIES
Authors: Efriyenty Dian 
Published: October 2021

ABSTRACTBased on the survey results for the last 3 years, data on food companies and the minimum turnover of accounts receivable and debt has increased and this has an impact on taking profits in the form of assets. These things can have an impact on the investment invested in shareholders. The purpose of this study is to assess the effect of short-term debt and accounts receivable turnover on asset returns. The samples in this study were 8 companies in the 2015-2019 period. The results of t-test analysis partially show that short-term debt does not have a significant effect on profitability, receivables turnover has a significant effect on profitability. Keywords: short-term debt, accounts receivable turnover, profitability
Osteosarcopenic obesity in cardiovascular patients. Controversial and open issues
Authors: Krivoshapova K. E. , Masenko V. L. , Bazdyrev E. D. , Barbarash O. L. 
Published: October 2021

See “Inflammaging in the pathogenesis of chronic non-communicable diseases”, Kim O. T. in Opinion of invited editor, pp. 54-55.The study of osteosarcopenic obesity (OSO) in patients with cardiovascular diseases (CVDs) in recent years has caused a dis-cussion on common pathogenesis of atherosclerosis, obesity, progressive loss of skeletal and muscle mass. Are these processes independent age-related conditions or comorbidities with common links of pathogenesis? The aim of this review was to analyze studies on OSO in patients with CVDs. We used following electronic databases: PubMed, Clinical Trials, Google Scholar, www.elibrary.ru. Based on this analysis, modern ideas on the etiology, epidemiology and pathogenesis of OSO in elderly and senile patients with atherosclerosis were described. The authors concluded that absence of standards for OSO diagnosis and inadequate clinical suspicion of specialists during routine examination is one of the main causes of its insufficient detection in elderly patients with CVDs. The results of analyzed studies allow us to consider the OSO and atherosclerotic changes as a single link of cardiovascular continuum. Eliminating the negative effect of chronic inflammation on human body should be considered as a key mechanism in the treatment of OSO and atherosclerosis. However, more research is needed in this area.
Pathogenetic rationale for using an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase and an antioxidant coenzyme Q<sub>10</sub> in the treatment and prevention of cardiovascular disease
Authors: Dzugkoev S. G. , Garmash O. Yu. , Dzugkoeva F. S. 
Published: October 2021

The review discusses atherosclerosis-related mechanisms of car-diovascular disease development, as well as the optimization of their prevention and treatment methods. Recent experimental and clinical studies have shown the important role of vascular endothelium in the development and progression of atherosclerosis. Myocardial ischemia, activation of free-radical processes and impaired bioenergetics initiate a decrease in production of nitric oxide, which plays major vasodilator role. In this regard, the scientists is interested in the search for new drugs that can affect the main pathogenetic links of coronary artery disease. Statins are currently the drugs of choice. However, they are not always effective and have an ambiguous effect on oxidative potential of myocardial cells and endothelial function. Moreover, inhibition of mevalonic pathway for cholesterol synthesis is accompanied by a deficiency of coenzyme Q10, which is the central cellular antioxidant that protects phospholipids of cell membranes from free radicals. Rationale of using coenzyme Q10 in the complex treatment and secondary prev ention of cardiovascular diseases, including coronary artery di sease, is discussed.