bluuebunny/crossref_metadata_2025_split huggingface dataset:
The COVID-19 Pandemic Affects Male Patients With Chronic Spontaneous Urticaria More Than Female Patients
Authors: Kulu Huzeyfe , Atasoy Mustafa , Özyurt Kemal , Maurer Marcus , Avcı Atıl , Akkuş Muhammet Reşat , Ertaş Ragıp 
Published: October 2021

IntroductionThe COVID-19 pandemic dramatically disrupts health care for patients with chronic diseases including chronic spontaneous urticaria (CSU). As of now, it is unknown if the effects of the pandemic in CSU are different than in other chronic diseases. We also do not know, if different groups of CSU patients, for example female and male patients, are affected differently.AimTo understand how CSU patients and subgroups are affected by the COVID-19 pandemic in their disease activity and control and treatment, using psoriasis as control.Patients and MethodsWe analyzed 399 patients (450 visits) with CSU or psoriasis assessed during August 2019, i.e. before the pandemic, or August 2020, i.e. during the pandemic, for changes in disease activity, disease control, and the treatment they used, and how these changes are linked to age, gender, and disease duration.ResultsMale but not female patients with CSU had markedly increased disease activity during the pandemic. CSU patients’ age or disease duration were not linked to changes. Male and female patients with psoriasis showed similar increases in disease activity and decreases in disease control. The rate of omalizumab treatment, during the pandemic, was unchanged in male patients and increased in female patients with CSU. The efficacy of omalizumab treatment, during the pandemic, was reduced in male patients but not female patients with CSU.ConclusionMale but not female CSU patients, during the COVID-19 pandemic, show loss of disease control linked to loss of omalizumab efficacy. The reasons for this need to be investigated.
A Review of Hot Gas Cleaning Techniques for Hydrogen Chloride Removal from Biomass-Derived Syngas
Authors: Marcantonio Vera , Müller Michael , Bocci Enrico 
Published: October 2021

Considering the pressing challenges of supply security and climate change, advanced processes to produce electricity and biofuels from biomass have to be developed. Biomass gasification is a very promising technology, but there is a lack of comprehensive reviews, specifically on the technologies for hydrogen chloride hot gas cleanup, which are necessary in order to work at the same temperature and respect the limits of advanced downstream components. In this review, the Cl content of the main biomasses in Europe is given, and data on syngas content and the tolerance of downstream equipment are highlighted. Hot gas cleaning technologies, which have the advantage of improved thermal efficiency are reviewed, analyzing the thermodynamic and primary and secondary methods. This review identifies NaAlO2 and Na2CO3 within 450–550 °C as the most effective sorbents, which are able to reduce the concentration of HCl below 1 ppm. Nevertheless, H2S cannot be simultaneously removed and has to be removed first, because it reduces the HCl adsorption sorbent capacity.
A CONDIÇÃO DE MOSSORÓ-RN COMO CIDADE DE PORTE MÉDIO EM SUA ÁREA DE INFLUÊNCIA
Authors: Almeida Rodrigo Emanoel de Sousa , Costa Ademir Araújo da , Benevides Héllen Jamilly , Sousa Erik Albino de 
Published: October 2021

As cidades médias vêm apresentando importante desenvolvimento regional fora das regiões metropolitanas e agregando valor econômico e social na área que ocupa. Assim, essas cidades desempenham papel importante na rede urbana nacional e regional. Mossoró no Rio Grande do Norte compõe esse quadro de cidades que vem ganhando destaque considerável nos estudos sobre cidade média e sua condição urbano e regional. O objetivo do presente trabalho é analisar a condição de Mossoró como cidade média no interior do estado e suas funções urbanas desempenhadas por ela no contexto urbano e regional. Para isso, foram realizadas leituras de artigos, dissertações e livros que auxiliaram na sua compreensão. Também foi feito o uso da pesquisa das Regiões de Influência das Cidades (REGIC) como forma de identificar a área de influência da cidade. Destarte, Mossoró consegue atrair um quantitativo importante de pessoas para o comércio (varejo e atacarejo) local, serviços de saúde, serviços bancários, turismo, trabalho e ensino superior. Além de ser beneficiada com a dinâmica de capitais, sendo uma realidade construída durante anos, resultando na sua condição de cidade média nos dias atuais.
MENYOAL PERAN ALUMNI (Analisis Manajemen Pemberdayaan Alumni UIN KHAS Jember)
Authors: Rahman Kholilur 
Published: October 2021

Tranformasi atau merubah bentuk Perguruan Tinggi Keagamaan Islam (PTKI) dari Sekolah Tinggi ke Institut atau dari Institut ke Universitas bukan merupakan pekerjaan yang mudah. Apalagi yang dirubah bentuknya adalah Perguruan Tinggi Keagamaan Islam Negeri (PTKIN). 8 (delapan) STAIN bersiap alih status menjadi IAIN, dan 9 (sembilan) IAIN menjadi UIN, termasuk di dalamnya IAIN Jember menjadi Universitas Islam Negeri KH. Achmad Shidiq (UIN Khas) Jember. Naskah ini mengulas tentang peran alumni (Khususnya Alumni S3 IAIN Jember) pada proses tranformasi status dari Insitut menjadi Universitas. Penelitian ini dilakukan dengan tujuan : (1) untuk mengetahui dan menganalisis bagaimana proses tranformasi IAIN Jember menjadi UIN Khas Jember sebagai wujud local wisdom (kearifan lokal), (2) untuk mengetahui peran almuni UIN Khas Jember. Penelitian ini menggunakan pendekatan diskriptif kualititatif, yaitu penelitian engan memahami fenomena secara holistik secara alamiah. Sumber penelitian ini adalah penelitian kepustakaan (library research), yaitu penelitian yang berbasis kajian teoritis, referensi serta literatur ilmiah lainnyaHasil penelitian ini menunjukkan bahwa : (1) Nilai local wisdom dalam proses tranformasi IAIN Jember menjadi UIN Khas Jember, meliputi: penghargaan sejarah, penegasan faham keagamaan, dan penegasan azas bagi UIN Khas Jember. (2) Peran almuni UIN Khas Jember sebagai katalisator, kontributor, public opinion, dan mover networking bagi pengembangan dan kemajuan UIN Khas Jember.
The organizational transformation of Islamic universities and colleges is not an easy task. Moreover, the transformation is under the authority of the state, namely the National Islamic Religious College ("State Islamic Religious College/PTKIN). Eight State Islamic colleges (STAIN) are preparing to become State Islamic Institute (IAIN) and nine IAIN become State Islamic University (UIN), including IAIN Jember to become UIN KH. Achmad Shidiq (UIN KHAS) Jember. This manuscript discusses the role of graduates (especially S-3 graduates of IAIN Jember) in the organizational transformation process from the State Islamic Institute to the State Islamic University. This study aims to: (1) analyze how the process of transforming IAIN Jember into UIN KHAS Jember is included in local wisdom; and (2) to find out the progress of the graduates of UIN Khas Jember. This study uses a qualitative descriptive approach that is to understand the phenomenon holistically naturally. This research method is library research, namely research based on theoretical studies, references, and other scientific literature. The results of this study are: (1) The value of local wisdom in the organizational transformation process of IAIN Jember into UIN KHAS Jember is historical appreciation, affirmation of religious ideology, and affirmation of principles for UIN KHAS Jember. (2) The graduates of UIN KHAS Jember act as catalysts, contributors, public opinion makers, and movers of networking for the development of UIN KHAS Jember.
Presence or Absence of Cognitive Partnership in Early School Education: Research Report
Authors: Kochanowska Ewa 
Published: October 2021

The main aim of the article is to present the results of preliminary qualitative research on the ways in which teachers of grades 1–3 of primary school understand cognitive partnership and the meanings they assign to it in their own school practice. The method of individual open-ended interview was used in the research.
On the basis of the obtained research results, it can be concluded that, in the opinion of the respondents, cognitive partnership is possible and even necessary in early school education. The teachers’ declarations show that cognitive partnership is present in their educational activities, but it is impossible to fully implement it due to the cognitive developmental features of children at the early school age. The vast majority of the respondents, when explaining the discussed concept, focused in their statements primarily on the intellectual aspect of cognitive partnership, but the importance of social relations between the teacher and the student/students in the process of gaining knowledge was emphasized less frequently. When explaining the concept of cognitive partnership, the surveyed teachers most often focused unilaterally either on the teacher’s actions or on the child’s activities that indicate cognitive partnership. The understanding of the discussed concept as a system of relations between the subjects of education, who co-decide about the course and effects of the education process, occurred much less frequently. The obtained results are a contribution to conducting further in-depth research, especially with regard to the place and manner of implementing the idea of ​​cognitive partnership in the practice of early school education.
FEATURES OF DIFFERENTIAL DIAGNOSIS OF URGENT SURGICAL ABDOMINAL PATHOLOGY DURING A PANDEMIC OF CORONAVIRUS INFECTION
Authors: Lesnoy V. V. , Lesna A. S. , Filonenko V. A. 
Published: October 2021

Summary. Aim. To analyze the features of differential diagnosis of urgent surgical pathology during a coronavirus infection pandemic.
Materials and methods. The work is based on the analysis of the results of additional examination of 28 patients at the admission department, who sought medical help in an urgent manner.
Results. The advantages and disadvantages of using instrumental methods for detecting atypical forms of coronavirus infection and acute abdominal pathology are analyzed. Based on this, a diagnostic algorithm was developed using express tests for the determination of COVID-19 and urgent ultrasound protocols, which made it possible to identify lung lesions without clinical symptoms in 8 (28.6 %) patients, and to confirm acute surgical pathology in 5 (17.9 %) patients.
Conclusion. Еxamining patients with suspected acute abdominal pathology for the purpose of differential diagnosis with the gastrointestinal form of COVID-19, it is necessary to use rapid tests for detecting antibodies to coronavirus infection and sonographic examination of the abdominal organs (FAST protocol), chest organs (BLUE protocol).
ENTERAL INSUFFICIENCY COURSE SEVERITY DEGREES DIAGNOSTICS IN PERITONITIS BY SMALL INTESTINAL MICROSCOPIC IMAGES PHASE MAPING
Authors: Polyovyy V. P. , Sydorchuk R. I. , Polyova S. P. , Palianytsia A. S. , Chepega I. G. 
Published: October 2021

Summary. The aim is to determine the efficiency of diagnostics of the enteric insufficiency syndrome severity in peritonitis by phase mapping of microscopic images of histological sections of the laboratory rats’ small intestine.
Material and methods. Seventy-eight white nonlinear rats of both sexes were selected, weighing from 180 to 220 g, underwent simulated mild, moderate and severe experimental peritonitis according to the standard method. Samples of optically thin histological sections of the small intestine of rats with different severity of the course of peritonitis were used as the research object.
Results. As a result of the study, a structural and logical scheme for studying the effectiveness of differential diagnosis of the severity of peritonitis by means of statistical analysis of the structure of the distribution of phases of microscopic images of biological preparations of rats was developed, which helped to determine the relationships between the distribution of statistical parameters of the 1st–4th orders, which characterize phase maps depending on the severity of the peritonitis course.
Conclusion. The revealed changes in the statistical structure of phase maps fully correlate with the measurement data for the polarization phase manifestations of the properties of the polycrystalline component of histological sections, both in the case of the phase measurement of polycrystalline blood films and the wall of the small intestine.
SURGICAL TREATMENT OF COMPLICATIONS AFTER STERNOTOMY
Authors: Boyko V. V. , Lykhman V. M. , Myroshnychenko D. O. , Shafer Yu. V. , Tkach S. V. , Merkulov A. O. , Bilodid E. O. , Batsman N. V. , Babich A. V. 
Published: October 2021

Summary. The article presents materials of laboratory and instrumental diagnostics of 44 patients with sternal osteomyelitis and comparative treatment with VAC - therapy and open method. Diagnosis was verified by multispiral computed tomography. Ultrasound showed the best results to control the cleaning and healing of sternotomy wounds. The bacterial spectrum showed a predominance of gram-positive microflora in 52.38 % of patients. The use of VAC therapy reduced the duration of hospitalization of patients from (20,3±2,7) to (13,6±5,8) days.
Materials and methods. We analyzed the results of treatment of 22 patients who were treated at the State Institution “V.T. Zayceva IGUS NAMSU “in the period from 2014 to 2020 with osteomyelitis of the sternum (OS) after sternotomies. The material for the bacterial study was the isolation of a sternal wound. The antibiotic susceptibility of the isolated bacterial cultures was studied by disco-diffusion method and on agar. Diagnosis of multislice computed tomography (MSCT) was performed using Toshiba Aquilion 64 (Japan).
Results and discussion. Wound infection was detected in 42 patients out of 44 examined. A total of 34 strains of microorganisms, representatives of different taxa. S. aureus was dominant and accounted for 23.81 % of the total number of isolates of this genus. In 14.28 % of cases there was contamination of S. epidermidis. E. coli and K. pneumonia 14.28 and 9.52 %, respectively. The most effective in vitro were lincomycin and especially carbopenems (imipenem).
Among the instrumental studies we performed fistulography, ultrasound diagnostics (ultrasound) and MSCT.
We used VAC therapy in 31 patients and in 13 patients by bandaging depending on the stage of the wound process. The duration was (4.7 ± 1.3) days.
There was a decrease in the duration of wound cleansing: with superficial sternal infection — (12.8 ± 5.2) and (4.7 ± 1.3) days; with deep sternal infection — (25.3 ± 1.4) and (10.9 ± 2.2) days; term of hospitalization of patients with superficial sternal infection — (27.3 ± 5.6) and (13.6 ± 5.8) days; term of hospitalization of patients with deep sternal infection — (41.2 ± 3.5) and (20.3 ± 2.7) days.
Conclusions. 1. In the diagnosis of OS should be preferred MSCT, which allows to verify the diagnosis in up to 99 % of cases, and the use of ultrasound to monitor the cleaning and healing of sternotomy wounds. The use of VAC therapy reduced the duration of hospitalization of patients from (20,3±2,7) to (13,6±5,8) days.
IN INTRA-ABDOMINAL INFECTIONS AND PERITONITIS
Authors: Kotov A. V. , Desyaterik V. I. , Mikhno S. P. 
Published: October 2021

Summary. Purpose of the reserche. To study changes in microflora and sensitivity of isolated strains to antibiotics using bacteriological research methods for intra-abdominal infections and peritonitis to determine their resistance when planning antibiotic therapy.
Results and discussion. The paper presents data from a retrospective analysis of the results of studies of microflora and its resistance in intra-abdominal infections (IAI) and peritonitis for 2 periods: I period — from january 2007 to december 2008, II period — from january 2018 to december 2019. The difference between period II and I was in the increase in the number of individual pathogenic strains of microorganisms. Thus, the number of Klebsiella spp. increased from 13.8 % to 23.8 %, which in absolute number of their total number amounted to a 73.5 %, ranking second in the overall structure among pathogens sown in IAI and peritonitis. The number of strains of Staphylococcus spp., Enterobacter spp., Acinetobacter spp. has also increased by 2.4–5.8 % respectively. Among the strains Klebsiella spp., E. coli and Staphylococcus spp. the number of poly- and multi-polyresistant forms has increased. Thus, the number of such forms among Klebsiella spp. increased from 19.2 to 44.5 %, Staphylococcus spp. — from 43.8 to 67.1 % and E. coli from 18.2 to 23.5 %, respectively.
Conclusions. Over the past 10 years, with IAI and peritonitis, the most significant changes were revealed on the part of pathogenic strains of Klebsiella spp., Staphylococcus spp. and Acinetobacter spp. Multidrug resistant strains were predominantly susceptible to carbapenems, semisynthetic ureidopenicillins, aminoglycosides, glycopeptides, oxazalidinones, phosphonoic acid derivatives. In the context of changes in the microbial landscape observed over the past decade, an increase in the number of poly- and multi-resistant forms of pathogenic microorganisms in IAI and peritonitis, the choice of antibiotics for rational therapy should be based solely on bacterioscopy and antibiograms.
AN INTEGRATED APPROACH TO THE TREATMENT OF PATIENTS WITH ACUTE PANCREATITIS
Authors: Drozdova A. G. , Parkhomenko K. Y. , Honcharova N. M. , Vovk V. A. , Payunov K. E. , Suplichenko M. V. 
Published: October 2021

Abstract. The aim of the study – to improve the results of surgical treatment of patients with acute pancreatitis.
Matherials and methods of the study. The results of the treatment of 103 patients with acute pancreatitis who were treated in the surgical department of the Municipal non-commercial enterprise of the Kharkov regional council «Regional Clinical Hospital» 2015 to 2020 were analyzed. All patients were divided into two groups: the main (56 patients) and the comparison group (47 patients). In the main group, the tactics of the “step-up approach” were applied and the principles of the ERAS concept (2018-2020) were implemented. In the comparison group (2015-2017), the ERAS principles were not implemented and the open method was mainly used as the standard surgical treatment.
Results of the study. Patients treated using the principles of “fast-track surgery” along with the “step-up approach” tactics, less likely to have postoperative complications and reduced the length of stay in the surgical department.
Conclusions. This example confirms the appropriateness of applying the principles of “fast-track surgery” in everyday surgical practice in the complex treatment of patients with acute pancreatitis, as the results of surgical treatment of this category of patients are improved and financial costs for treatment are reduced.
MEDICAL DRONES — AN INNOVATION OF THE PUBLIC DISASTER MEDICINE SERVICE
Authors: Volyansky P. B. , Yadchenko D. M. , Mosov S. P. , Pechiborsch V. P. , Yakimets V. M. , Khoroshun E. M. , Pechiborshch O. V. , Yakimets V. V. 
Published: October 2021

Summary. Purpose. Investigate the use of unmanned aerial vehicles in the interests of providing emergency assistance to the population. Consider unmanned aerial vehicles as a tool for medical protection of victims in emergency situations.
Materials and methods. The study used regulatory documents, scientific publications. The analysis of the use of unmanned aerial vehicles for medical protection of the population in Ukraine and the leading countries of the world is carried out.
Results. On the basis of the analysis, the advantages of the use of unmanned aerial vehicles as a tool for the medical protection of victims have been determined. The prospects for the further development of unmanned aircraft for work in the emergency zone are considered.
EXPERIENCE OF USING NPWT-THERAPY IN THE TREATMENT OF COMBAT INJURIES OF SOFT TISSUES OF THE LIMBS AND BODY
Authors: Haida Ya. I. , Muradian K. R. , Petrushenko S. V. , Herasymenko O. S. , Okolets A. V. 
Published: October 2021

Summary. Aim. NPWT-therapy (Negative-pressure wound therapy) or VAC-therapy (Vacuum Assisted Clousur) - a modern method of wound healing, which significantly improves the course of all stages of the wound process and is relevant today due to the large number of wounded during hostilities in eastern Ukraine. Often these injuries are combined and lead to the formation of large soft tissue defects.
The aim of the study. Improving the results of treatment of the wounded with extensive defects of the soft tissues of the torso and extremities through the use of NPWT therapy.
Materials and methods. Under our supervision in the period from 2017 to 2020 there were 60 wounded who were hospitalized in the surgical departments of the Military Medical Clinical Center of the Southern Region, who received vacuum therapy in the treatment of wounds. 38 (63.3%) had gunshot wounds to the extremities, and 22 (36.7%) had soft tissue injuries to the torso. The age of the wounded ranged from 19 to 58 years, among them young people under 30 years of age.
Before installing the device, it was necessary to perform surgical treatment with excision of necrotic tissue and removal of fibrin layers. Negative pressure was set at -125 mm Hg. Art. in the non-stop mode for soft tissue defects of the extremities and variable pressure in the -40 mm Hg mode. Art. -70 mm Hg Art. for wounds of the anterior abdominal wall. The duration of treatment with NPWT therapy was from 5 to 25 days. The systems were replaced at least once every 3-5 days. Criteria for discontinuation of NPWT therapy were: cleansing the wound of necrotized tissues and fibrin, improving clinical performance, filling the wound defect with granulation tissue.
Results and discussion. The use of this method of treatment allowed to close wound defects by autodermoplasty in 21 patients (35%), primary-delayed sutures in 11 (18%), secondary sutures in 15 (25%) and local tissue plastics in 13 (22%).
Complications after NPWT therapy in the form of re-suppuration of the wound, bleeding or perforation of hollow organs and large vessels were not observed.
Conclusions. The use of NPWT therapy can significantly increase the effectiveness of comprehensive treatment of the wounded with damage to the soft tissues of the torso and extremities. It allows you to quickly clean the wound surface, fill the wound defect with granulation tissue and prepare the wound for plastic closure.
Photometric Observations of KEPLER Mission’s Eclipsing Binary EPIC 201458798 (V0337Leo)
Authors: Altunin Ivan 
Published: October 2021

AbstractTwo follow up observing sessions of Kepler’s Eclipsing Binary star system EPIC 201458798 (from the K2 mission) were conducted in the Spring of 2018 and 2019 utilizing the 0.4 m subnet of the Los Cumbres Observatory Global Telescope network. The total duration of observations for each session (∼77 days) was comparable with the duration of observations by the Kepler telescope ∼80 days. 900–1000 images were obtained during each session with an integrating time around 1 minute, resulting in about 800 mag measurements per session. In contrast, the Kepler telescope provided almost continuous measurements of this star with an integration time per image of about 30 minutes, resulting in about 3250 photometric points. In contrast to the Kepler telescope measurements, which were conducted with one very broad filter, the observations in this study used four filters:B,V,ip, andrp. This data was processed and the period, time of minimum, and depth of the eclipses was determined. The results were compared with the data obtained by the Kepler telescope and other historical records.