bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of low temperature and nitrogen addition during cold stratification on seed germination of Korean pine (Pinus koraiensis)
Authors: Song Yuan , Gao Xiaoye 
Published: May 2021

Pinus koraiensis Siebold & Zucc. seeds are primarily dormant following dispersal, restricting the natural regeneration of populations. The aim of this study was to determine the combined effects of increasing low temperature and nitrogen addition during cold stratification on seed germination. We stratified the seeds at 0 °C, 5 °C, and 10 °C for 3.5 months. At each cold stratification temperature, seeds were subjected to 0 (0 nitrogen), 0.08 (low nitrogen), 0.16 (medium nitrogen), and 0.25 mol·L–1 (high nitrogen) nitrate additions. Seed germination response was tested at 25/15 °C and 10/5 °C. Under 0 nitrogen and high nitrogen levels, increasing cold stratification temperature did not markedly affect seed germination at 25/15 °C, but significantly inhibited seed germination at 10/5 °C. At medium nitrogen levels, seed germination at both 25/15 °C and 10/5 °C significantly decreased. At low nitrogen levels, increasing cold stratification temperature significantly decreased germination percentage at 25/15 °C from 86.7% (0 °C) to 50.2% (10 °C) but did not markedly change seed germination percentage at 10/5 °C. We suggest that the effect of increasing cold stratification temperature on seed germination of P. koraiensis depends on both the level of nitrogen addition during cold stratification and subsequent incubation temperature after cold stratification.
Progression of Preclinical Heart Failure: A Description of Stage A and B Heart Failure in a Community Population
Authors: Young Kathleen A. , Scott Christopher G. , Rodeheffer Richard J. , Chen Horng H. 
Published: May 2021

Background:
The aims of this study are to evaluate the rate of progression of preclinical (Stage A and B) heart failure, identify associated characteristics, and evaluate long-term outcomes.

Methods:
Retrospective review of the Olmsted County Heart Function Study. Individuals categorized as Stage A or B heart failure at initial visit that returned for a second visit 4 years later were included. Logistic regression analyses evaluated group differences with adjustment for age and sex.

Results:

At visit 1, 413 (32%) individuals were classified as Stage A and 413 (32%) as Stage B. By visit 2, 146 (35%) individuals from Stage A progressed with the vast majority (n=142) progressing to Stage B. In comparison, a total of 23 (6%) individuals progressed from Stage B. A greater rate of progression was seen for Stage A compared with Stage B (8.7 per 100 person-years [95% CI, 7.4–10.2] versus 1.4 per 100 person-years [95% CI, 0.9–2.1];
P
<0.001). NT-proBNP correlated with progression for Stage B (
P
=0.01), but not for Stage A (
P
=0.39). A multivariate model found female sex (odds ratio, 1.65 [95% CI, 1.05–2.58];
P
=0.03), increased E/e’ (odds ratio, 1.13 [95% CI, 1.02–1.26],
P
=0.02), and beta blocker use (odds ratio, 2.19 [95% CI, 1.25–3.82],
P
=0.006) were associated with progression for Stage A. There was a signal that cardiovascular mortality was higher in individuals who progressed, although not statistically significant (
P
=0.06 for Stage A and
P
=0.05 for Stage B).

Conclusions:
There is significant progression of preclinical heart failure in a community population, with progression rates higher for Stage A. NT-proBNP correlated with progression for Stage B, but not for Stage A. No statistically significant differences in long-term outcomes were seen. Study results have clinical implications important to help guide future heart failure screening and prevention strategies.
Alleged Basic Meanings of the Hebrew Verb qdš “Be Holy”: An Exercise in Comparative Hebrew Lexicography
Authors: Clines David J. A. 
Published: May 2021

Abstract
Most Hebraists are familiar with the claim that the “basic meaning” of the Hebrew verb qdš is “to separate.” It was adopted by BDB, and is referred to by HALOT. This paper argues that the claim is unlikely to be correct.
In searching for the origins and rationale for this claim, which goes back at least to Reuchlin (1505), I encountered some other views propounded by Hebrew lexica of the past 500 years about the “basic meaning” of the root, including “be clean” (e.g., Gesenius, 1833), “begin” (e.g., Buxtorf, 1615) and (surprisingly) “be unclean” (e.g., Pagninus, 1529). These proposals also will be shown to lack adequate support.
I will argue that the verb qdš “be holy” and its derivatives have no underlying meaning apart from their denotation of the deity personally and of what belongs to the deity, such as his temple, his priests, his sabbaths, etc.
The imperative-hortative paradigm in Biblical Hebrew in typological and diachronic view
Authors: Notarius Tania 
Published: May 2021

Abstract
In this paper, applying the cross-linguistic criterion of formal homogeneity, I represent the morphological properties of the imperative-hortative paradigm (volitive modals) in classical Biblical Hebrew: each personal form is marked individually; the 1st person hortative (traditionally called cohortative) has two freely distributed spelling variants, with and without the ending -ɔ̄; the 2nd person (imperative) has two contrasted forms—the basic one and one marked by the ending -ɔ̄; the 3rd person (jussive) has just one allomorph. The imperative—hortative forms are not available in syntactic subordination, but they are used in different types of dependent clauses introduced by the conjunction w- “and”. One of the major hallmarks of the Biblical Hebrew verbal system is the influence of other paradigms—w-perfect, imperfect, and infinitive absolute—on the imperative-hortative paradigm. The linguistic diversity in the Biblical Hebrew corpus points to other types of the imperative-hortative paradigm that are explained in terms of the linguistic chronology—the archaic type and the late type of the imperative-hortative paradigm in Biblical Hebrew. In the conclusion, I will point to the circularity in the diachronic development of the volitive forms in Biblical Hebrew and to the correlation of the diachronic development with the cross-linguistic typology.
Time Speeds Up During Flow States: A Study in Virtual Reality with the Video Game Thumper
Authors: Rutrecht Hans , Wittmann Marc , Khoshnoud Shiva , Igarzábal Federico Alvarez 
Published: May 2021

Abstract
Flow is a mental state characterized by deep absorption during challenging activities, which was first studied by Mihaly Csikszentmihalyi. One of the defining characteristics of this state is the loss of the sense of time. Despite the widespread scientific interest in flow, there are few quantitative studies specifically on the aspect of time perception. The present study focuses on the relation between time perception and flow states in the context of video game play. Participants (n = 100) played the rhythm game Thumper for 25 minutes in one of two conditions: in virtual reality (VR) or on a computer screen (2D). Participants who played the game in VR performed better and had a stronger feeling of presence than those who played in 2D. Thumper was flow-inducing regardless of condition and the more flow participants experienced the less they thought about time and the faster time passed subjectively. The total score obtained by players as an objective measure of player performance was positively correlated with flow states, indicating that the more flow participants experienced, the better they played.
Time Compression in Virtual Reality
Authors: Mullen Grayson , Davidenko Nicolas 
Published: May 2021

Abstract
Virtual-reality (VR) users and developers have informally reported that time seems to pass more quickly while playing games in VR. We refer to this phenomenon as time compression: a longer real duration is compressed into a shorter perceived experience. To investigate this effect, we created two versions of a labyrinth-like game. The versions are identical in their content and mode of control but differ in their display type: one was designed to be played in VR, and the other on a conventional monitor (CM). Participants were asked to estimate time prospectively using an interval production method. Participants played each version of the game for a perceived five-minute interval, and the actual durations of the intervals they produced were compared between display conditions. We found that in the first block, participants in the VR condition played for an average of 72.6 more seconds than participants in the CM condition before feeling that five minutes had passed. This amounts to perceived five-minute intervals in VR containing 28.5% more actual time than perceived five-minute intervals in CM. However, the effect appeared to be reversed in the second block when participants switched display conditions, suggesting large novelty and anchoring effects, and demonstrating the importance of using between-subjects designs in interval production experiments. Overall, our results suggest that VR displays do produce a significant time compression effect. We discuss a VR-induced reduction in bodily awareness as a potential explanation for how this effect is mediated and outline some implications and suggestions for follow-up experiments.
Description of four new species of the spider genus Euryopis Menge, 1868, with new records from Brazil (Araneae, Theridiidae, Hadrotarsinae)
Authors: RODRIGUES EVERTON NEI LOPES , MARTA KIMBERLY S. , FIGUEIREDO CASSIANO P. 
Published: May 2021

The spider genus Euryopis Menge, 1868 (Theridiidae) currently comprises 76 described species worldwide and only two described species from Brazil and none for Bolivia. In this paper four new species of Euryopis from Brazil and Bolivia are described and illustrated: Euryopis candiota n. sp.; Euryopis nasuta n. sp.; Euryopis catarinensis n. sp. all from Brazil and Euryopis boliviensis n. sp. from Bolivia. New records from Brazil are provided for E. camis Levi, 1963 and E. spinifera O. Pickard-Cambridge, 1895.
Uncertainty in the Parameterization of Surface Fluxes under Unstable Conditions
Authors: Srivastava Piyush , Sharan Maithili 
Published: May 2021

AbstractIn this study, an attempt has been made to analyze the possible uncertainties in the parameterization of surface fluxes associated with the form of non-dimensional wind and temperature profile functions used in weather and climate models under convective conditions within the framework of Monin-Obukhov similarity theory (MOST). For this purpose, these functions, which are commonly known as similarity functions, are classified into four categories based on the resemblance in their functional behaviour. The bulk flux algorithm is used for the estimation of transfer coefficients of momentum and heat using four different classes of similarity functions. Uncertainty in the estimated values of fluxes is presented in the form of deviation in the predicted values of momentum and heat transfer coefficients and their variation with the Monin-Obukhov stability parameter. The analysis suggests that a large deviation in the values of estimated fluxes might occur if different forms of similarity functions are utilized for the estimation of surface fluxes. Recommendations are made for the form of similarity function for momentum based on the analysis of one year-long turbulence observations over an Indian region. The study suggests that there is a distinct need to carry out a careful analysis of turbulence data in free convective conditions for determining a consistent functional form of the similarity functions to be utilized in the atmospheric models universally.
Blizzard Conditions in the Canadian Arctic: Observations and Automated Products for Forecasting
Authors: Burrows William R. , Mooney Curtis J. 
Published: May 2021

AbstractBlizzard conditions occur regularly in the Canadian Arctic, with high impact on travel and life there. These extreme conditions are challenging to forecast for this vast domain because the observation network is sparse and remote sensing coverage is limited. To establish occurrence statistics we analyzed METeorological Aerodrome Reports (METARs) from Canadian Arctic stations between October and May 2014-2018. Blizzard conditions occur most frequently in open tundra east and north of the boreal forest boundary, with highest frequency found on the northwest side of Hudson Bay and over flat terrain in central Baffin Island. Except in sheltered locations, the reported cause of reduced visibility is blowing snow without precipitating snow in about one-half to two-thirds of METARs made by a human observer, even higher at some stations.We produce three products that forecast blizzard conditions from post-processed NWP model output. The blizzard potential (BP), generated from expert’s rules, is intended for warning well in advance of areas where blizzard conditions may develop. A second product (BH) stems from regression equations for the probability of visibility ≤ 1 km in blowing snow and/or concurrent snow derived by Baggaley and Hanesiak (2005). A third product (RF), generated with the Random Forest ensemble classification algorithm, makes a consensus YES/NO forecast for blizzard conditions. We describe the products, provide verification, and show forecasts for a significant blizzard event. Receiver Operator Characteristic curves and critical success index scores show RF forecasts have greater accuracy than BP and BH forecasts at all lead times.
Kidney function and obstructive lung disease: a bidirectional Mendelian randomisation study
Authors: Park Sehoon , Lee Soojin , Kim Yaerim , Cho Semin , Kim Kwangsoo , Kim Yong Chul , Han Seung Seok , Lee Hajeong , Lee Jung Pyo , Joo Kwon Wook , Lim Chun Soo , Kim Yon Su , Kim Dong Ki 
Published: May 2021

BackgroundAdditional study is warranted to investigate the causal effects between kidney function and obstructive lung disease.MethodsThis study was a bidirectional two-sample Mendelian randomisation (MR) analysis. The Chronic Kidney Disease Genetics (CKDGen) genome-wide association study (GWAS) meta-analysis for estimated glomerular filtration rate (eGFR) including individuals of European ancestry (n=567 460) provided the genetic instrument for kidney function and outcome summary statistics. A GWAS for forced expiratory volume in 1 s (FEV1)/forced vital capacity (FVC) including individuals of European ancestry from the UK Biobank (n=321 047) provided the genetic instrument for FEV1/FVC and outcome data. A polygenic score (PGS) analysis was performed to test the causal estimates from kidney function to binary obstructive lung disease outcomes, including COPD, asthma and FEV1/FVC <70%, and to perform nonlinear MR with individual-level UK Biobank data.ResultsThe causal estimates by summary-level MR indicated that genetically predicted increased kidney function was significantly associated with increased FEV1/FVC z-scores (10% increase in eGFR; β=0.055, 95% CI 0.024–0.086). The PGS for increased eGFR showed a significant association with a reduced risk of FEV1/FVC <70% (OR 0.93, 95% CI 0.87–0.99), COPD (OR 0.93, 95% CI 0.87–0.99) and late-onset (age ≥50 years) asthma (OR 0.93, 95% CI 0.88–0.99). The nonlinear MR demonstrated that the causal effect from eGFR to FEV1/FVC was apparent in eGFR ranges <60 mL·min−1·1.73 m−2. Conversely, genetically predicted FEV1/FVC showed nonsignificant causal estimates of eGFR change (β=0.568%, 95% CI −0.458–1.605%).ConclusionThis study supports kidney function impairment as a causative factor for obstructive lung disease.
Occupational inhalant exposures and longitudinal lung function decline
Authors: Skaaby Stinna , Flachs Esben Meulengracht , Lange Peter , Schlünssen Vivi , Marott Jacob Louis , Brauer Charlotte , Çolak Yunus , Afzal Shoaib , Nordestgaard Børge G. , Sadhra Steven , Kurmi Om , Bonde Jens Peter Ellekilde 
Published: May 2021

BackgroundAirborne exposures at the workplace are believed to be associated with lung function decline. However, longitudinal studies are few, and results are conflicting.MethodsParticipants from two general population-based cohorts, the Copenhagen City Heart Study and the Copenhagen General Population Study, with at least two lung function measurements were followed for a mean of 9 years (range 3–27 years). Occupational exposure was assigned to each year of follow-up between the two lung function measurements by a job exposure matrix. Associations between mean occupational exposure per year and mean annual decline in forced expiratory volume in 1 s (FEV1) were investigated using linear mixed-effects models according to cohort and time period (1976–1983 and 2003–2015). We adjusted for sex, height, weight, education, baseline FEV1and pack-years of smoking per year during follow-up.ResultsA total of 16 144 individuals were included (mean age 48 years and 43% male). Occupational exposure to mineral dusts, biological dusts, gases and fumes and a composite category was not associated with FEV1decline in analyses with dichotomised exposure. In analyses with an indexed measure of exposure, gases and fumes were associated with an FEV1change of −5.8 mL per unit per year (95% CI −10.8– −0.7 mL per unit per year) during 1976–1983, but not during 2001–2015.ConclusionIn two cohorts from the Danish general population, occupational exposure to dusts, gases and fumes was not associated with excess lung function decline in recent years but might have been of importance decades ago.
Body mass index and in-hospital mortality in patients with acute exacerbation of idiopathic pulmonary fibrosis
Authors: Awano Nobuyasu , Jo Taisuke , Yasunaga Hideo , Inomata Minoru , Kuse Naoyuki , Tone Mari , Morita Kojiro , Matsui Hiroki , Fushimi Kiyohide , Nagase Takahide , Izumo Takehiro 
Published: May 2021

BackgroundIdiopathic pulmonary fibrosis (IPF) is an interstitial lung disease characterised by chronic fibrosis, and acute exacerbation of IPF (AE-IPF) is the leading cause of death in patients with IPF. Data on the association between the body mass index (BMI) and prognosis of AE-IPF are lacking. This study was performed to evaluate the association between BMI and in-hospital mortality in patients who developed AE-IPF using a national inpatient database.MethodsUsing the Japanese Diagnosis Procedure Combination database, we retrospectively collected data of inpatients with AE-IPF from 1 July, 2010 to 31 March, 2018. We performed a multivariable logistic regression analysis to evaluate the association between all-cause in-hospital mortality and BMI, categorised as underweight (<18.5 kg·m−2), low-normal weight (18.5–22.9 kg·m−2), high-normal weight (23.0–24.9 kg·m−2), overweight (25.0–29.9 kg·m−2) and obese (≥30.0 kg·m−2).ResultsIn total, 14 783 patients were eligible for this study. The in-hospital mortality rate was 59.0%, 55.0%, 53.8%, 54.8% and 46.0% in the underweight, low-normal weight, high-normal weight, overweight and obese groups, respectively. Underweight patients had a significantly higher mortality rate (OR 1.25, 95% CI 1.10–1.42) and obese patients had a significantly lower mortality rate (OR 0.71, 95% CI 0.54–0.94) than low-normal weight patients.ConclusionAmong patients with AE-IPF, the underweight group had higher mortality and the obese group had lower mortality.
Tongue strength and swallowing dynamics in chronic obstructive pulmonary disease
Authors: Epiu Isabella , Gandevia Simon C. , Boswell-Ruys Claire L. , Wallace Emma , Butler Jane E. , Hudson Anna L. 
Published: May 2021

BackgroundSwallowing disorders occur in COPD, but little is known about tongue strength and mastication. This is the first assessment in COPD of tongue strength and a test of mastication and swallowing solids (TOMASS).MethodsAnterior tongue strength measures were obtained in 18 people with COPD, aged 73±11 years (mean±sd), and 19 healthy age-matched controls, aged 72±6 years. Swallowing dynamics were assessed using an eating assessment tool (EAT-10), timed water swallow test (TWST), and TOMASS. Swallowing measures were compared to an inhibitory reflex (IR) in the inspiratory muscles to airway occlusion (recorded previously in the same participants).ResultsTongue strength was similar between COPD and controls (p=0.715). Self-assessed scores of dysphagia EAT-10 were higher (p=0.024) and swallowing times were prolonged for liquids (p=0.022) and solids (p=0.003) in the COPD group. During TWST, ∼30% of COPD group showed clinical signs of airway invasion (cough and wet voice), but none in the control group. For solids, the COPD group had ∼40% greater number of chews (p=0.004), and twofold-higher number of swallows (p=0.0496). Respiratory rate was 50% higher in COPD group than controls (p <0.001). The presence of an IR was not related to better swallowing outcomes, but signs of airway invasion were associated with a delayed IR.ConclusionDysphagia in stable COPD is not due to impaired anterior tongue strength, but rather swallowing–breathing discoordination. To address dysphagia, aspiration and acute exacerbations in COPD, therapeutic targets to improve swallowing dynamics could be investigated further.
The association between intracompartmental pressure and skeletal muscle recovery after tibial diaphyseal fractures: an ambispective cohort study
Authors: Tian Shengjie , Chang Shimin , Lu Yaogang , Zhu Jianhua , Kong Xuqiang 
Published: May 2021

Abstract
Background
Due to the special anatomy of the lower leg, tibial diaphyseal fracture causes increased intracompartmental pressure (ICP). Not only is this increased ICP the manifestation of skeletal muscle injury, but it induces further deterioration of the injury. The aim of this study was to assess the association between short-term ICP elevation and long-term skeletal muscle recovery after severe limb trauma.

Methods
In this single-center ambispective cohort study, we retrospectively screened and recruited a cohort of tibial diaphyseal fracture patients with integrated ICP data during the early post-traumatic period, and performed a prospective observational study to evaluate their skeletal muscle recovery through long-term follow-up and MR imaging after the removal of the implants. We analyzed the association between ICP elevation and skeletal muscle recovery using statistical methods.

Results
A total of 46 patients with healed fractures underwent intramedullary nail removal and MR imaging. The absolute values of the Pearson product-moment correlation coefficients between various ICP parameters and the cross-sectional area ratio (CSAR) ranged from 0.588 to 0.793, and the correlation coefficients between the ICP parameters and the average T2-weighted signal intensity ratio (T2SIR) varied from 0.566 to 0.775. Statistically significant associations were observed between the ICP parameters and the MR imaging parameters when simple linear regression analysis was performed. Among the ICP parameters, the accumulated ΔP (ΔP = diastolic blood pressure minus ICP) had the highest determination coefficient and explained 62.1% and 59.1% of the variance in CSAR and T2SIR, respectively.

Conclusions
Short-term ICP elevation was associated with long-term skeletal muscle recovery following tibial diaphyseal fracture, especially for ICP data that integrated time factors.

Level of evidence
Level 3.