bluuebunny/crossref_metadata_2025_split huggingface dataset:
College students' credibility assessments of GenAI‐generated information for academic tasks: An interview study
Authors: Choi Wonchan , Bak Hyerin , An Jiaxin , Zhang Yan , Stvilia Besiki 
Published: December 2024

AbstractThe study explored college students' use of generative artificial intelligence (GenAI) tools, such as ChatGPT, for academic tasks and their perceptions and behaviors in assessing the credibility of GenAI‐generated information. Semistructured interviews were conducted with 25 college students in the United States. Interview transcripts were analyzed using the qualitative content analysis method. The study identified various types of academic tasks for which students used ChatGPT, including writing, programming, and learning. Guided by two models of credibility assessment Hilligoss and Rieh (2008); Metzger (2007), six factors influencing students' motivation and ability to assess the credibility of GenAI‐generated information were identified (e.g., task salience, social pressure). We also identified 9 constructs (e.g., refinedness, explainability), 5 heuristics (e.g., inter‐ and intrasystem consistency heuristics), and 10 cues (e.g., version and tone) used by students to assess the credibility of GenAI‐generated information. This study provides theoretical and empirical findings regarding students' use of GenAI tools in the academic context and credibility evaluation of the system outputs using rich, qualitative interview data.
Acoustic Exaggeration Enhances Speech Discrimination in Young Autistic Children
Authors: Yu Luodi , Ban Lizhi , Yi Aiwen , Xin Jing , Li Suping , Wang Suiping , Mottron Laurent 
Published: December 2024

ABSTRACTChild‐directed speech (CDS), which amplifies acoustic and social features of speech during interactions with young children, promotes typical phonetic and language development. In autism, both behavioral and brain data indicate reduced sensitivity to human speech, which predicts absent, decreased, or atypical benefits of exaggerated speech signals such as CDS. This study investigates the impact of exaggerated fundamental frequency (F0) and voice‐onset time on the neural processing of speech sounds in 22 Chinese‐speaking autistic children aged 2–7 years old with a history of speech delays, compared with 25 typically developing (TD) peers. Electroencephalography (EEG) data were collected during passive listening to exaggerated and non‐exaggerated syllables. A time‐resolved multivariate pattern analysis (MVPA) was used to evaluate the potential effects of acoustic exaggeration on syllable discrimination in terms of neural decoding accuracy. For non‐exaggerated syllables, neither the autism nor the TD group achieved above‐chance decoding accuracy. In contrast, for exaggerated syllables, both groups achieved above‐chance decoding, indicating significant syllable discrimination, with no difference in accuracy between the autism and TD groups. However, the temporal generalization patterns in the MVPA results revealed distinct neural mechanisms supporting syllable discrimination between the groups. Although the TD group demonstrated a left‐hemisphere advantage for decoding and generalization, the autism group displayed similar decoding patterns between hemispheres. These findings highlight the potential of selective acoustic exaggeration to support speech learning in autistic children, underscoring the importance of tailored, sensory‐based interventions.
Associations of Serum Manganese, Zinc, Copper, and Selenium Concentrations With Autism Spectrum Disorders in Chinese Children: A Case–Control Study
Authors: Zhang Yong , Xie Fang , Li Sheng , Li Ying , Yang Liting , Wang Zhen , Lei Jinlin , Guo Huailan 
Published: December 2024

ABSTRACTImbalances in several trace elements related to antioxidant function may lead to autism spectrum disorder (ASD)‐related physiological dysfunction. Nonetheless, contradictory results have been found on the connection between these elements and ASD, and studies of their joint effects and interactions have been insufficient. We therefore designed a case–control study of 152 ASD children and 152 age‐ and sex‐matched typically developing (TD) children to explore the individual and combined associations of manganese (Mn), zinc (Zn), copper (Cu), and selenium (Se) with ASD. Compared with TD, ASD has lower Zn and Se levels and higher Cu levels. The restricted cubic spline model showed J‐shaped non‐linearity, L‐shaped non‐linearity, and positive linearity correlations between Mn, Zn, Cu, and ASD. Zn and Cu were negatively and positively correlated with ASD symptoms, respectively. The superoxide dismutase (SOD) mediated 50.53% and 39.07% of the association between Zn, Se, and ASD, respectively. Bayesian kernel machine regression (BKMR) confirmed a U‐shaped correlation between the element mixtures and ASD. Interactions of Mn with the other three elements and Cu with Zn were also observed. Our results confirm that the independent and combined exposure to the four trace elements was associated with ASD, with oxidative stress being an important mechanism. Due to the potential interactions between the elements, further research is needed to explore their involvement in the pathogenesis and progression of ASD from a combined perspective, as well as the beneficial and harmful concentration ranges.
Poa annua ecology, biology, and integrated weed management practices in turfgrass
Authors: McCurdy James D. , Bowling Rebecca G. , de Castro Edicarlos B. , Patton Aaron J. , Kowalewski Alec R. , Mattox Clint M. , Brosnan James T. , Ervin David E. , Askew Shawn D. , Goncalves Clebson G. , Elmore Matthew T. , McElroy J. Scott , McNally Brandon C. , Pritchard Benjamin D. , Kaminski John E. , Gannon Travis W. , Unruh J. Bryan , Bagavathiannan Muthukumar V. 
Published: December 2024

AbstractPoa annua L. is one of the most widespread and troublesome weeds of turfgrass. It persists as both an annual and perennial and is adaptable to almost any static maintenance regime, including adaptation to mowing heights and evolution of herbicide resistance. This management guide is intended to provide stakeholders with a summary of new and existing knowledge on integrated Poa annua management. Here we review the basic biology and ecology, as well as practical integrated weed management (IWM) strategies developed for its control.
High Performance of Cs2AgBiBr6 Perovskite‐based Photodetectors by Adding DEAC
Authors: Minjie Wu , Teng Chen , Xuedan Chen , Maoxue Wang , Chen LV , Kai Meng , Shuanglong Yuan 
Published: December 2024

AbstractPerovskite‐based photodetectors (PDs) are broadly utilized in optical communication, non‐destructive testing, and smart wearable devices due to their ability to convert light into electrical signals. However, toxicity and instability hold back their mass production and commercialization. The lead‐free Cs2AgBiBr6 double perovskite film, promised to be an alternative, is fabricated by electrophoretic deposition (EPD), which compromises film quality. Herein, we improved the quality of the Cs2AgBiBr6 films and the performance of PDs by adding N‐acetylethylenediamine (DEAC) to Cs2AgBiBr6 perovskite precursor for EPD, in which the ligand DEAC provides a pair of lone electrons to Bi3+, forming coordinate covalent bonds. The optimized PDs have high detectivity, up to 4.4×1012 Jones, and high stability in the air. The high‐performance, flexible Cs2AgBiBr6 perovskite PDs were fabricated on this basis, it also achieved the detectivity up to 3.2×1012 Jones with excellent bending cycle stability. These results propose a feasible approach to improving the crystallization of double perovskite thin films by introducing ligands during the EPD process. Furthermore, they demonstrate enhanced optoelectronic performance, indicating that this method is also applicable to halide perovskites, offering an effective strategy to improve their film quality.
Property Tuning in N‐Methylpyrrole Azo‐Photoswitches via Modification of the Peripheral Substituents
Authors: Jelínková Veronika , Dellai Angela , Verwaerde Lauryne , Rodriguez Vincent , Fecková Michaela , Vachtlová Martina , Podlesný Jan , Klikar Milan , Sempé Bixente , Hugget Matt , Pařík Patrik , Pytela Oldřich , Castet Frédéric , Růžičková Zdeňka , Bureš Filip 
Published: December 2024

AbstractDifferently substituted pyrrole‐azo–benzene molecular photoswitches were prepared in a straightforward synthetic way. Their fundamental properties were investigated by XRD analysis, differential scanning calorimetry, thermogravimetric analysis, cyclic voltammetry, UV–Vis absorption spectroscopy, Hyper‐Rayleigh Scattering, and NMR spectroscopy; the experimental results were further corroborated by DFT calculations. Thermal robustness, the HOMO/LUMO levels, and the absorption properties were altered mostly by substituting the N–methylpyrrole moiety and further fine‐tuned by modifying the benzene substituents. The pyrrole substituent also proved crucial for the second‐order non–linear optical (NLO) response as well as the photoswitching performance. Both fast and slow molecular switches can be designed with the half–life of the (Z) –isomer ranging from 48 seconds to 23.28 hours and the E/Z molar ratio up to 12/88. This comprehensive study allowed elucidation of the fundamental structure‐property relationships and subsequently addresses the key aspects of the property tuning via substitution in molecular azo‐photoswitches.
Total Synthesis of the Conjugation‐Ready Hexasaccharides of Pseudomonas aeruginosa Serotype O17 O‐Antigen via One‐Pot Glycosylation
Authors: Tian Guangzong , Bao Jialong , Chen Guodong , Zou Xiaopeng , Qin Chunjun , Hu Jing , Yin Jian 
Published: December 2024

Comprehensive SummaryThe eradication of Pseudomonas aeruginosa infections is becoming increasingly complex due to the emergence of multidrug‐resistant strains, underscoring the urgent need for novel therapeutic strategies. Currently, no vaccine is available to prevent P. aeruginosa infections and the development of glycoconjugate vaccines based on P. aeruginosa lipopolysaccharides (LPS) presents significant challenges. To explore the immunological activity of the serotype O17 O‐antigen, we present the first chemical synthesis of two hexasaccharides derived from the O17 O‐antigen of P. aeruginosa, which possess distinct sequences. The synthesis of these two target hexasaccharides was accomplished using a chemoselective one‐pot [2+2+2] assembly strategy and a common step‐wise synthesis, respectively. The formation of β‐mannosamine glycosidic linkages in products 1 and 2, was achieved through a direct stereoselective 1,2‐cis‐glycosylation involving 4,6‐O‐benzylidene‐induced conformational locking facilitated by Ph2SO/Tf2O pre‐activation, and an indirect 1,2‐trans‐β‐glycosylation alongside SN2 substitution of azide groups at C2, respectively. The efficient synthesis of these conjugation‐ready oligosaccharides from the O‐antigen of P. aeruginosa serotype O17 will provide foundational materials for identifying key antigens and developing glycoconjugate vaccines.
Deficiency of ATF3 facilitates both angiotensin II‐induced and spontaneously formed aortic aneurysm and dissection development by activating cGAS–STING pathway
Authors: Du Yifan , Hu Poyi , Ding Xiangchao , Wang Dashuai , Luo Jingjing , Le Sheng , Ren Lingyun , Chen Manhua , Ye Ping , Xia Jiahong 
Published: December 2024

AbstractBackgroundSporadic aortic aneurysm and dissection (AAD) is a critical condition characterised by the progressive loss of vascular smooth muscle cells (VSMCs) and the breakdown of the extracellular matrix. However, the molecular mechanisms responsible for the phenotypic switch and loss of VSMCs in AAD are not fully understood.Methods and resultsIn this study, we employed a discovery‐driven, unbiased approach. This approach encourages us to explore the unknown functions of activating transcription factor 3 (ATF3) rather than merely confirming existing hypotheses, while no assumptions were made about ATF3 prior to the experiments. We ensured the unbiased nature of our assessment by conducting morphological evaluations with two independent observers in a blinded manner. We identified elevated expression of ATF3 in both human sporadic AAD tissues and mouse AAD models. VSMC‐specific ATF3 conditional knockout (Atf3 cKO) mice showed notable enlargement, dissection and rupture in both thoracic and abdominal aortic regions after exposure to Ang II. Interestingly, older Atf3 cKO mice exhibited spontaneous aortic dissections and senescence of the aortic wall. Mechanistically, ATF3 deficiency led to the degradation of P21 through ubiquitination. Impaired DNA repair in VSMCs resulted in micronuclei formation in the cytoplasm, activating the cyclicGMP‐AMP synthase‐ stimulator of interferon genes (cGAS–STING) pathway and inducing VSMC phenotypic switching and apoptosis. Finally, both pharmacological complementation of P21 function and knockdown of STING expression alleviated ATF3 deficiency‐induced AAD.ConclusionsOur study indicates that ATF3 is essential for genomic DNA stability in VSMCs through the P21–cGAS–STING pathway, suggesting that enhancing ATF3 expression in VSMCs could help prevent sporadic AAD.Key points
ATF3 deficiency led to degradation of P21 through ubiquitination, which abolished the G1 phase arrest.
VSMCs had no time window to repair the damaged DNA, leading to generation of micronuclei in cytoplasm.
Cytoplasmic micronuclei facilitating the activation of cGAS–STING pathway, thus inducing the phenotypic switch and apoptosis of VSMCs
Enhancing IoT‐Enabled Healthcare Applications by Efficient Cluster Head and Path Selection Using Fuzzy Logic and Enhanced Particle Swarm Optimization
Authors: Othmen Salwa , Khdhir Radhia , Belghith Aymen , Hamouid Khaled , Lhioui Chahira , Elmourssi Doaa 
Published: December 2024

ABSTRACTLeveraging Internet of Things (IoT) technologies in healthcare, including wireless sensor networks (WSN) and new generation networks, facilitates the integration of diverse medical equipment and enables smart interactions among them. This innovation contributes significantly in meeting the needs of healthcare professionals and improving the quality of life of patients. However, ensuring efficient communication within IoT systems is crucial to meet the critical demands of healthcare, such as real‐time monitoring and emergency situations. This paper proposes a novel approach for determining cluster heads and selecting efficient paths in IoT‐enabled healthcare applications. The cluster head selection process utilizes a fuzzy logic mechanism, considering factors like energy, distance, and latency. Subsequently, the particle swarm optimization (PSO) technique is employed to identify optimal pathways for routing. MATLAB‐based simulations have been conducted to evaluate the proposed approach in terms of several key metrics, including average delay, packet delivery ratio, energy efficiency, and throughput. The results of the evaluation demonstrate significant improvements over comparable works. Specifically, our solution achieves a packet delivery ratio of 91.3%, an average delay of 0.12 s, a throughput of 60.1 bps, and an energy efficiency of 8.9 J/bit. These findings underscore the effectiveness of our proposed approach in meeting the stringent requirements of IoT‐enabled healthcare systems, particularly by achieving lower delays and higher throughput.
Carboxylic Acid‐Catalysed Transamidation of Boc‐Protected Diketopiperazines (Boc‐DKPs) for Peptide Synthesis
Authors: Kon Kazumasa , Yamamoto Hisashi 
Published: December 2024

AbstractA carboxylic acid‐catalysed transamidation of Boc‐protected diketopiperazines (Boc‐DKPs) was developed in this study, which allowed access to various tripeptides featuring a D‐proline residue in good‐to‐high yields within 30 min. Subsequent coupling reactions between the Boc‐DKPs and di‐, tri‐, and tetrapeptide esters were successfully performed, furnishing the corresponding tetra‐, penta‐, and hexapeptides.
The use of plant based materials in architecture: A review
Authors: Yildiz Ali , Koçak Ahmet Burak 
Published: December 2024

AbstractDue to the rapidly increasing human population since the beginning of the 20th century, and with the rapid development of industrialization, the use of raw materials has increased significantly in the last century. As a result, limited resources began to decrease rapidly. The destruction on the natural environment, environmental pollution and the effects of global warming have reached alarming levels. On the other hand, the need for raw materials and energy continues to increase. At this point, it is extremely important to meet today's needs in a sustainable way, without causing environmental pollution and without consuming limited resources. In order to meet the need for sustainable building materials, studies on the use of plant biomass in the production of building materials are increasing due to reasons, such as having low environmental impact, low cost, and renewable. Since building materials produced from plant biomass are largely biodegradable, they also contribute to the prevention of environmental pollution. In this context, the plants examined in the study were examined in detail in an order from woody plants to herbaceous plants and from plants commonly used in architecture to less commonly used plants.
The Cognitive Profile in Adolescents With Anorexia Nervosa and the Relationship With Autism and ADHD: A Pilot Study
Authors: Dobrescu Sandra Rydberg , Dahlin Karin , Karjalainen Louise , Montonen Annelie Bördal , Klint Helena , Stenberg Ingrid , Karlsson Gunilla Paulson , Wentz Elisabet 
Published: December 2024

ABSTRACTObjectiveWe aimed to examine the cognitive profile in adolescents with anorexia nervosa (AN) and its association with traits of autism spectrum disorder (ASD) and ADHD. In addition, resemblance in the cognitive profile between youths with AN and their parents was explored.MethodsAdolescent females with acute AN (n = 20) and a healthy comparison group (n = 28) completed neuropsychological tasks of set‐shifting (Trail making test, Wisconsin Card Sorting Test) and central coherence (Rey Complex Figures Task, Group Embedded Figures Test, object assembly subtest). In the AN group, mothers and fathers (n = 31) also completed the neuropsychological tasks. Traits of ASD and ADHD were assessed. The AN group was reassessed after weight gain.ResultsWeight‐restored AN adolescents scored higher on the Group Embedded Figures Test than a comparison group (p < 0.001). No other set‐shifting and central coherence differences were found across groups. A father‐child correlation emerged in the object assembly subtest (r = 0.53, p = 0.035). ASD and ADHD traits were common in the AN group and not only related to starvation. No associations were found between neuropsychological deficits and traits of ASD and ADHD.ConclusionsScant support was found for weaker central coherence in weight‐recovered adolescents with AN. Set‐shifting impairments could not be observed in young females with acute AN or after weight recovery.
Of Fire and Water Microarchaeological Evidence of Mining, Rituals and Floods in North Tyrol's Kropfsberg Mine (Austria)
Authors: Cereda Susanna , Goldenberg Gert , Staudt Markus , Tropper Peter 
Published: December 2024

ABSTRACTKropfsberg, located near Reith im Alpbachtal, in North Tyrol (Austria), has been exploited for its copper ores for centuries, since at least the Early Iron Age. Excavations conducted in 2020 by the University of Innsbruck exposed the detailed stratigraphic sequence of the mine, leading to a surprising discovery: what was initially believed to be only a site for mineral extraction showed clear indications of ritual use during the Roman period and Late Antiquity. These cultic layers are characterised by abundant charcoals, animal bones and almost 200 votive coins, and suggest that the mine served during this period as a Mithraeum. Using micromorphology and µXRF, along with macroscopic, hydro‐ and geomorphological information about the mine and its surroundings, we reconstructed the processes that led to the deposition of sediments within this artificial cave. Our analyses indicate that remains of ceremonial fires and offerings were deposited within a cultic pit, rather than being spread over the floor. Also, evidence suggests that the cultic use of the mine likely ceased before the area surrounding the mine was flooded, potentially due to the damming of the Inn River caused by a significant rock fall during the Roman period. We also traced the phases following the inundation, including the cave's reopening after a period of abandonment, and identified a sequence of mining backfills that provide evidence of the site's subsequent secular use. Ultimately, the study sheds new light on the cultural and geomorphological dynamics of the Inn Valley during the Roman Period and the Late Antiquity, while underscoring the importance of integrating microarchaeological approaches to disentangle the complex interaction of cultural and environmental influences, even in historical (artificial) cave contexts.
One‐Day Brentuximab–Bendamustine (120 mg/m2) Every 21 Days is a Feasible, Safe and Effective Treatment for Relapsed/Refractory Hodgkin Lymphoma
Authors: Moatti H. , Brice P. , Laroque M‐C. , Di Blasi R. , Wencel J. , Delory T. , Madelaine‐Chambrin I. , Schmidt‐Hieber C. , Ravdan O. , Thieblemont C. , Renaud L. 
Published: December 2024

ABSTRACTBrentuximab vedotin (BV)‐bendamustine (90 or 120 mg/m2 day 1 and 2) every 28 days is an effective treatment for relapsed/refractory Hodgkin lymphoma (R/R HL) but associated to high toxicity especially for elderly patients. We conducted in St Louis Hospital, Paris, between 2015 and 2021 a retrospective single‐center analysis of 44 patients with R/R HL treated with one‐day BV‐bendamustine (120 mg/m2) every 21 days. Sixteen percent of patients were ≥ 60 years old (yo). Seventy‐three percent of patients received total number of cycles without interruption nor adaptation. No patient ≥ 70 yo required treatment interruption. Dose adjustment was necessary for 18% of patients. Infusion‐related reaction (36%) occurred always at cycle 2 and was the only cause of treatment interruption. One febrile neutropenia, one non‐documented septic shock, one pyelonephritis on transplanted kidney and one COVID complicated by cytopenias were reported. Sixteen percent patients presented a peripheral sensory neuropathy, 7% and 4% respectively grade 3–4 neutropenia and thrombocytopenia. Overall response was 84%, with 73% of complete remission. Median progression‐free survival was of 19.8 months (95% CI 13.1‐NR) and median overall survival was not reached with a median follow‐up of 31 months. We suggest that one‐day BV‐bendamustine (120 mg/m2) ever 21 days is a safe and feasible treatment for R/R HL especially for elderly patients.