bluuebunny/crossref_metadata_2025_split huggingface dataset:
Role of cardiac magnetic resonance strain analysis in patients with hypoplastic left heart syndrome in evaluating right ventricular (dys)function: a systematic review
Authors: Gasparini Marisa , Cox Natasha 
Published: February 2021

Abstract OBJECTIVESRight ventricular dysfunction predicts death in patients with hypoplastic left heart syndrome (HLHS), but differences in morphology and loading conditions make calculation of the ejection fraction (EF), a challenging measure of its function. Our goal was to evaluate how strain measurements with cardiac magnetic resonance feature tracking could be used to evaluate right ventricular function in patients with HLHS.METHODSA systematic search of the literature was performed by 2 independent researchers using the terms ‘population’, ‘intervention’, ‘comparison’, ‘outcome’ and ‘time criteria’. PubMed and the Ovid database were searched according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines.RESULTSOur review included 8 studies with 608 participants with ventricular strain values obtained using cardiac magnetic resonance feature tracking. After stage I palliation, global strain was reduced in patients after a hybrid procedure and a right ventricle-to-pulmonary artery conduit compared with a modified Blalock–Taussig shunt despite similar EFs. Global longitudinal strain did not differ between stage II and stage III (Fontan) palliation. Fontan patients had significantly impaired global longitudinal and circumferential strain compared to the left ventricular strain of the controls. Studies of Fontan patients that included patients with HLHS who were part of a cohort with a single right ventricle showed impaired global circumferential strain compared with the cohort with a single left ventricle, with controls, and over time. In this group, impaired global circumferential strain was associated with major adverse cardiac events.CONCLUSIONSCardiac magnetic resonance feature tracking can be used in patients with HLHS to evaluate RV strain and demonstrate differences between surgical strategies, over time and compared with controls. It could be used alongside clinical symptoms and EF values to detect ventricular dysfunction.
The Paris Night: A Flâneur in Post-Revolutionary Paris
Authors: Weintraub J 
Published: February 2021

Abstract
This annotated English translation of an article written by Eugène Briffault one year after the 1830 July Revolution presents a unique testimony of a city in a state of post-revolutionary transition. Drawn with the pen of a realist novelist and observed with the eye of a practised reporter, ‘The Paris Night’ takes the reader on a journey through the streets of a city seemingly under martial law, from the haunts of journalists, into the vice-dens of the Palais-Royal, past the hectic activity of Les Halles and into streets still bearing the scars of the recent Revolution. Along with the ubiquitous military patrols, the author encounters streetwalkers, ragpickers and other denizens of the night until he reaches the Chaillot Heights to contemplate a ‘revolution escamotée’, a popular revolt which had been ‘smuggled away’. Along with a brief biography of Briffault, J. Weintraub’s introduction places the essay in the context of its time.
Chromosome-Level Genome Assembly of the Common Chaffinch (Aves: Fringilla coelebs): A Valuable Resource for Evolutionary Biology
Authors: Recuerda María , Vizueta Joel , Cuevas-Caballé Cristian , Blanco Guillermo , Rozas Julio , Milá Borja 
Published: February 2021

Abstract
The common chaffinch, Fringilla coelebs, is one of the most common, widespread, and well-studied passerines in Europe, with a broad distribution encompassing Western Europe and parts of Asia, North Africa, and the Macaronesian archipelagos. We present a high-quality genome assembly of the common chaffinch generated using Illumina shotgun sequencing in combination with Chicago and Hi-C libraries. The final genome is a 994.87-Mb chromosome-level assembly, with 98% of the sequence data located in chromosome scaffolds and a N50 statistic of 69.73 Mb. Our genome assembly shows high completeness, with a complete BUSCO score of 93.9% using the avian data set. Around 7.8% of the genome contains interspersed repetitive elements. The structural annotation yielded 17,703 genes, 86.5% of which have a functional annotation, including 7,827 complete universal single-copy orthologs out of 8,338 genes represented in the BUSCO avian data set. This new annotated genome assembly will be a valuable resource as a reference for comparative and population genomic analyses of passerine, avian, and vertebrate evolution.
The efficacy of transbronchial indocyanine green instillation for fluorescent-guided wedge resection
Authors: Sekine Yasuo , Koh Eitetsu , Hoshino Hidehisa 
Published: February 2021

Abstract

OBJECTIVES
The purpose of this study was to investigate the feasibility of lung wedge resection by combining 3-dimensional (3D) image analysis with transbronchial indocyanine green (ICG) instillation, in order to delineate the intended area for resection.

METHODS
From December 2017 to July 2020, 28 patients undergoing wedge resection (17 primary lung cancers, 11 metastatic lung tumours) were enrolled, and fluorescence-guided wedge resection was attempted. Virtual sublobar resections were created preoperatively for each patient using a 3D Image Analyzer. Surgical margins were measured in each sublobar resection simulation in order to select the most optimal surgical resection area. After transbronchial instillation of ICG, near-infrared thoracoscopic visualization allowed matching of the intended area for resection to the virtual sublobar resection area. To investigate the effectiveness of ICG instillation, the clarity of the ICG-florescent border was evaluated, and the distance from the true tumour to the surgical margins was compared to that of simulation.

RESULTS
Mean tumour diameter was 12.4 ± 4.3 mm. The entire targeted tumour was included in resected specimens of all patients (100% success rate). The shortest distances to the surgical margin via 3D simulation and by actual measurement of the specimen were11.4 ± 5.4 and 12.2 ± 4.1 mm, respectively (P = 0.285) and were well correlated (R2 = 0.437). While all specimens had negative malignant cells at the surgical margins, one loco-regional recurrence was observed secondary to the dissemination of neuroendocrine carcinoma.

CONCLUSIONS
ICG-guided lung wedge resection after transbronchial ICG instillation and preoperative 3D image analysis allow for adequate negative surgical margins, providing decreased risk of local recurrence.
Polling in New Democracies and Electoral Malpractice: The Case of Brazil
Authors: Lloyd Ryan , Turgeon Mathieu 
Published: February 2021

AbstractIn many developing democracies, polling often comes with elevated levels of bias and variance. We argue that electoral malpractice can be one reason why. We build a theory and test it with data from elections between 2002 and 2014 in Brazil. We find that polling errors are larger in: (a) elections with many undecided voters and large imbalances in financial resources among campaigns; (b) the poorer Northeast region of Brazil, which is more closely associated with patronage and vote buying; and (c) low-profile, low-information elections. Our analysis serves as a cautionary tale for interpreting polling in democracies like Brazil, even if/when other sources of error in the polling industry are mitigated.
CSF1R defines the mononuclear phagocyte system lineage in human blood in health and COVID-19
Authors: Combes Theo W , Orsenigo Federica , Stewart Alexander , Mendis A S Jeewaka R , Dunn-Walters Deborah , Gordon Siamon , Martinez Fernando O 
Published: February 2021

SummaryMononuclear phagocytes defend tissues, present antigens, and mediate recovery and healing. To date, we lack a marker to unify mononuclear phagocytes in humans or that informs us about their origin. Here, we reassess mononuclear phagocyte ontogeny in human blood through the lineage receptor CSF1R, in the steady state and in COVID-19. We define CSF1R as the first sensitive and reproducible pan-phagocyte lineage marker, to identify and enumerate all conventional monocytes, and the myeloid dendritic cells. In the steady state, CSF1R is sufficient for sorting and immuno-magnetic isolation. In pathology, changes in CSF1R are more sensitive than CD14 and CD16. In COVID-19, a significant drop in membrane CSF1R is useful for stratifying patients, beyond the power of cell categories published thus far, which fail to capture COVID-19 specific events. Importantly, CSF1R defines cells which are neither conventional monocytes nor DCs, which are missed in published analysis. CSF1R decrease can be linked ex vivo to high CSF1 levels. Blood assessment of CSF1R+ cells opens a developmental window to the Mononuclear Phagocyte System in transit from bone marrow to tissues, supports isolation and phenotypic characterisation, identifies novel cell types, and singles out CSF1R inhibition as therapeutic target in COVID-19 and other diseases.
Nanog-mediated stem cell properties are critical for MBNL3-associated paclitaxel resistance of ovarian cancer
Authors: Sun Xueqin , Diao Xinghua , Zhu Xiaolin , Yin Xuexue , Cheng Guangying 
Published: February 2021

Abstract
Paclitaxel (PTX) is the standard first-line treatment of ovarian cancer, but its efficacy is limited by multidrug resistance. Therefore, it is crucial to identify effective drug targets to facilitate PTX sensitivity for ovarian cancer treatment. Seventy PTX-administrated ovarian cancer patients were recruited in this study for gene expression and survival rate analyses. Muscleblind-like-3 (MBNL3) gain-of-function and loss-of-function experiments were carried out in ovarian cancer cells (parental and PTX-resistant) and xenograft model. Cancer cell viability, apoptosis, spheroids formation, Nanog gene silencing were examined and conducted to dissect the underlying mechanism of MBNL3-mediated PTX resistance. High expression of MBNL3 was positively correlated with PTX resistance and poor prognosis of ovarian cancer. MBNL3 increased cell viability and decreased apoptosis in ovarian stem-like cells, through upregulating Nanog. This study suggests the MBNL3-Nanog axis is a therapeutic target for the treatment of PTX resistance in ovarian cancer management.
The Long-Term Consequences of Free School Choice
Authors: Lavy Victor 
Published: February 2021

Abstract
I study the long-term consequences of an effective free school choice program that targeted disadvantaged students in Israel two decades ago. I show that the program led to significant gains in post-secondary education through increased enrolment in academic and teachers’ colleges without any increase in enrolment in research universities. Free school choice also increased earnings at the adulthood of treated students. Male students had much larger improvements in college schooling and labor market outcomes. Female students, however, experienced higher increases in marriage and fertility rates, which most likely interfered with their schooling and labor market outcomes.
Collisional (de-)excitation of protonated cyanoacetylene (HC3NH+) by helium at low and moderate temperatures
Authors: Al Mogren M Mogren , Ben Abdallah D , Al Harbi S Dhaif Allah , Al Salhi M S , Hochlaf M 
Published: February 2021

ABSTRACT
Protonated cyanoacetylene, HC3NH+, is detected in astrophysical media, where it plays a key role as an intermediate in the chemistries of HCN/HNC and of cyanopolyynes. We first generated a potential energy surface (PES) describing the intermonomer interaction between HC3NH+ and He in Jacobi coordinates using the highly correlated CCSD(T)-F12/aug-cc-pVTZ ab initio methodology. Then, scattering calculations based on an exact close-coupling quantum-scattering technique were done to obtain pure rotational cross-sections for the rotational (de-)excitation of HC3NH+ after collision with He for total energies up to 2500 cm−1. These cross-sections are used to deduce the collision rates in the 5–350 K temperature range for the low-lying rotational levels of HC3NH+ (up to $j\,\, = \,\,15$). In addition, we generated an average PES for the HC3NH+–H2 system. The preliminary results show that the H2($j_{\mathrm{H_2}} = 0$) and He state-to-state de-excitation cross-sections have similar magnitudes, even though the H2 cross-sections are larger by a factor of 2–2.5. This work should help with the accurate derivation of protonated cyanoacetylene abundances in non-local thermodynamical equilibrium astrophysical media. These will put more constraints on the chemical pathways involving the formation and destruction of HC3NH+ while going back to the cyanopolyyne family and more generally those parts of nitrogen-containing molecular chemistry.
Registration and imaging polarimetry of the Fe 6374 Å red coronal line during the 2017 total solar eclipse
Authors: Liang Y , Qu Z Q , Chen Y J , Zhong Y , Song Z M , Li S Y 
Published: February 2021

ABSTRACT
Strict registration is critical for imaging polarimetry; a highly accurate registration approach to the coronal image and imaging polarimetry of the Fe 6374 Å red coronal line have been researched in this paper. In order to improve the registration accuracy, this paper proposes the idea of image enhancement based on blind deconvolution combined with noise-adaptive fuzzy equalization algorithms. After image enhancement, the cross-correlation registration algorithm achieves better results. To diagnose a low-temperature corona, the polarization brightness of the red coronal line data and the Mauna Loa Solar Observatory (MLSO)/KCor data are compared to study the structural features and polarization information of the inner corona. We found that the polarization brightness radiation of the red coronal line has overall features similar to that of the MLSO/KCor data, but it has more detailed features, such as the cavity, polar plume, and interplume characteristics. Active regions, polar plumes, and interplumes show similar performance in red coronal line intensity, polarization brightness, degree of linear polarization, K-corona, and electron density along with the radial height. An interesting finding is that the polarization brightness of the red coronal line changes drastically along with the radial height across the cavity above the solar west limb, while neither the K-corona nor the electron density changes obviously. This seems to be a piece of possible evidence indicating that the red coronal line is not unpolarized in the cavity region.
Nonunion Rates After Anterior Cervical Discectomy and Fusion: Comparison of Polyetheretherketone vs Structural Allograft Implants
Authors: Ryu Won Hyung A , Richards Dominick , Kerolus Mena G , Bakare Adewale A , Khanna Ryan , Vuong Victoria D , Deutsch Harel , Fontes Ricardo , O’Toole John E , Traynelis Vincent C , Fessler Richard G 
Published: February 2021

Abstract

BACKGROUND
Although advances in implant materials, such as polyetheretherketone (PEEK), have been developed aimed to improve outcome after anterior cervical discectomy and fusion (ACDF), it is essential to confirm whether these changes translate into clinically important sustained benefits.

OBJECTIVE
To compare the radiographic and clinical outcomes of patients undergoing up to 3-level ACDF with PEEK vs structural allograft implants.

METHODS
In this cohort study, radiographic and symptomatic nonunion rates were compared in consecutive patients who underwent 1 to 3 level ACDF with allograft or PEEK implant. Prospectively collected clinical data and patient-reported outcome (PRO) scores were compared between the allograft and PEEK groups. Regression analysis was performed to determine the predictors of nonunion.

RESULTS
In total, 194 of 404 patients met the inclusion criteria (79% allograft vs 21% PEEK). Preoperative demographic variables were comparable between the 2 groups except for age. The rate of radiographic nonunion was higher with PEEK implants (39% vs 27%, P = .0035). However, a higher proportion of nonunion in the allograft cohort required posterior instrumentation (14% vs 3%, P = .039). Patients with multilevel procedures and PEEK implants had up to 5.8 times the risk of radiographic nonunion, whereas younger patients, active smokers, and multilevel procedures were at higher risk of symptomatic nonunion.

CONCLUSION
Along with implant material, factors such as younger age, active smoking status, and the number of operated levels were independent predictors of fusion failure. Given the impact of nonunion on PRO, perioperative optimization of modifiable factors and surgical planning are essential to ensure a successful outcome.
Focal myocarditis in a young male with SARS-CoV-2 infection
Authors: Meel Ruchika , Ramsamy Tyral D , Narsing Rajiv , Wong Michelle 
Published: February 2021

ABSTRACT
A 31-year- old male with no comorbidities presented with chest discomfort and shortness of breath following SARS-CoV-2 infection. Primary viral myocarditis was confirmed with the aid of cardiac biomarkers and cardiac magnetic resonance (CMR) imaging. Herein, we detail his clinical presentation, management and highlight the role of CMR in viral myocarditis.
Movers and Stayers
Authors: Morris Irwin L. 
Published: February 2021

Abstract
Democrats once dominated the “Solid South.” By the turn of the 21st century, Republicans had taken control. We are in the midst of the dawning of new, more progressive era. Theories explaining Republican growth provide little guidance, but a new perspective—Movers and Stayers theory—explains this recent growth in Democratic support and the ways in which population growth has produced it. Migratory patterns play a significant role in southern politics. Young, well-educated in-migrants fostered Republican growth in the last century. Today, these increasingly progressive young, well-educated movers are growing the Democratic Party. Movers bring their politics to their new communities. Their progressivism fosters the same among long-term residents (stayers) in their new communities. But the declining communities they left show the effects of their exit. In our racialized partisan environment, white stayers respond to the threat of declining communities by shifting to the right and identifying with the Republican Party. Conversely, African Americans respond to community threat by maintaining their progressivism. Few Latinos live in declining communities; Latino stayers in fast growing communities become more Democratic. While movers of retirement age are more conservative than younger movers, they are more liberal than those who retire in place—not quite the demographic windfall Republicans in aging areas have hoped for. These dynamics are altering the southern political landscape, and differences between growing areas and declining areas are accelerating. Absent a wholesale reinvention of southern politics along the lines of class or (possibly) age, the current partisan trajectory does not bode well for Republicans. The COVID-19 pandemic will not change that.
Deceitful Media
Authors: Natale Simone 
Published: February 2021

Abstract
Artificial intelligence (AI) is often discussed as something extraordinary, a dream—or a nightmare—that awakens metaphysical questions on human life. Yet far from a distant technology of the future, the true power of AI lies in its subtle revolution of ordinary life. From voice assistants like Siri to natural language processors, AI technologies use cultural biases and modern psychology to fit specific characteristics of how users perceive and navigate the external world, thereby projecting the illusion of intelligence. Integrating media studies, science and technology studies, and social psychology, Deceitful Media examines the rise of artificial intelligence throughout history and exposes the very human fallacies behind this technology. Focusing specifically on communicative AIs, Natale argues that what we call “AI” is not a form of intelligence but rather a reflection of the human user. Using the term “banal deception,” he reveals that deception forms the basis of all human-computer interactions rooted in AI technologies, as technologies like voice assistants utilize the dynamics of projection and stereotyping as a means for aligning with our existing habits and social conventions. By exploiting the human instinct to connect, AI reveals our collective vulnerabilities to deception, showing that what machines are primarily changing is not other technology but ourselves as humans.&#x2028;Deceitful Media illustrates how AI has continued a tradition of technologies that mobilize our liability to deception and shows that only by better understanding our vulnerabilities to deception can we become more sophisticated consumers of interactive media.
Russian Soft and Sharp Power Resources
Authors: Stoner Kathryn E. 
Published: February 2021

Abstract
Beyond its reformed and upgraded traditional military capabilities, Russia under Vladimir Putin’s regime has also developed some new abilities and redeployed some old Soviet-era techniques to battle the West for global hearts and minds. In one sense they are forms of soft power as understood by Joseph Nye. These are power assets like the use of social media to promote Russian interests, traditional media, cultural centers, and goodwill emergency aid, but distinct from the way Nye defines the term as a passive pull toward the goals of a particular country’s preferences, Russian policymakers have used soft power to in a sense “wage friendship.” That is, they employ soft power resources as part of their foreign policy toolkit to further state interests. This chapter also looks at what has become known as “sharp” power—which includes cyber means to shape information environments in Russia’s favor. Various aspects of Russian sharp power include cyber theft and release of information, planting false stories and using fake social media accounts to launder and amplify a message, as well as purchasing Facebook and Twitter ads to further preferred candidates in foreign elections. The chapter includes a discussion of Russian use of sharp power capabilities in the US presidential election in 2016, as well as elsewhere.
Taking the Judges Seriously v. Grand Theories
Authors: Stapleton Jane 
Published: February 2021

Abstract
Chapter 1 describes the approach of reflexive tort scholarship and how it depends on a clear understanding of the environment of judicial decision-making. Part of that environment is the conception that judicial ‘lawmaking’ is ‘retrospective’, by which is usually meant that it is imposed retroactively. Yet retroactivity is in sharp tension with the fundamental principle that situations should be judged according to the law as it was at that time. To resolve this tension, the text offers a conception of the common law as ‘living’, that it evolves in line with changes in society. Later, litigation invites the ultimate court to articulate this evolution and how the law stood at the time that the parties interacted. The descriptive claims of Grand Theories are contrasted with reflexive tort scholarship, which accommodates key aspects of judicial decision-making, such as the heterogeneity of judicial reasons, in ways that those descriptive claims cannot.