bluuebunny/crossref_metadata_2025_split huggingface dataset:
Glossifungites gingrasi n. isp., a probable subaqueous insect domicile from the Cretaceous Ferron Sandstone, Utah
Authors: King M. Ryan , La Croix Andrew D. , Gates Terry A. , Anderson Paul B. , Zanno Lindsay E. 
Published: January 2021

AbstractA new ichnospecies, Glossifungites gingrasi n. isp., is described from multiple locations in basal sand-filled coastal plain distributary channels of the Turonian (Upper Cretaceous) Ferron Sandstone (central Utah). Glossifungites gingrasi n. isp. is attributed to the ichnogenus Glossifungites based on the presence of scratch imprints, passive fill, and a tongue-shaped structure, yet the new ichnospecies is distinct because it displays transverse bioglyphs that run perpendicular to the planiform structure, which contrasts to the axis parallel bioglyphs present in the ichnospecies G. saxicava. The transverse arrangement of ornamentation exhibited by G. gingrasi n. isp. is observed in modern subaqueous insect burrows produced by mayfly and chironomid larvae, and constitutes a way to differentiate insect-generated burrows from structures produced by crustaceans that are known to create other Glossifungites ichnospecies. Differentiating insect- from crustacean-generated burrows is significant because it provides a way to distinguish bioturbation by marine-recruited fauna from that produced by freshwater fauna in the rock record, making G. gingrasi n. isp. a valuable ichnological tool for paleoenvironmental and stratigraphic interpretation. While G. gingrasi n. isp. may represent a burrow created by a variety of filter-feeding subaqueous insects, the large size of G. gingrasi n. isp. in the Ferron Sandstone suggests that the largest specimens are probable mayfly burrows and supports the assertion that burrowing mayflies (e.g., Polymitarcyidae and Ephemeridae) adapted to domicile filter-feeding during or prior to the Turonian.UUID: http://zoobank.org/a033b22f-bf09-481a-975e-3a1b096154cc
Engaging with the science and politics of biodiversity futures: a literature review
Authors: Wyborn Carina , Louder Elena , Harfoot Mike , Hill Samantha 
Published: January 2021

SummaryFuture global environmental change will have a significant impact on biodiversity through the intersecting forces of climate change, urbanization, human population growth, overexploitation, and pollution. This presents a fundamental challenge to conservation approaches, which seek to conserve past or current assemblages of species or ecosystems in situ. This review canvases diverse approaches to biodiversity futures, including social science scholarship on the Anthropocene and futures thinking alongside models and scenarios from the biophysical science community. It argues that charting biodiversity futures requires processes that must include broad sections of academia and the conservation community to ask what desirable futures look like, and for whom. These efforts confront political and philosophical questions about levels of acceptable loss, and how trade-offs can be made in ways that address the injustices in the distribution of costs and benefits across and within human and non-human life forms. As such, this review proposes that charting biodiversity futures is inherently normative and political. Drawing on diverse scholarship united under a banner of ‘futures thinking’ this review presents an array of methods, approaches and concepts that provide a foundation from which to consider research and decision-making that enables action in the context of contested and uncertain biodiversity futures.
Originalism from the Soft Southern Strategy to the New Right: The Constitutional Politics of Sam Ervin Jr
Authors: SAWYER LOGAN 
Published: January 2021

AbstractAlthough originalism’s emergence as an important theory of constitutional interpretation is usually attributed to efforts by the Reagan administration, the role the theory played in the South’s determined resistance to civil rights legislation in the 1960s actually helped create the Reagan coalition in the first place. North Carolina Senator Sam Ervin Jr., the constitutional theorist of the Southern Caucus, developed and deployed originalism because he saw its potential to stymie civil rights legislation and stabilize a Democratic coalition under significant stress. Ervin failed in those efforts, but his turn to originalism had lasting effects. The theory helped Ervin and other conservative southerners explain to outsiders and to themselves why they shifted from support for an interventionist state powerful enough to enforce segregation to an ideology founded on individual rights and liberty. It thus eased the South’s integration with the emerging New Right.
Neurobehavioral correlates of impaired emotion recognition in pediatric PTSD
Authors: Heyn Sara A. , Schmit Collin , Keding Taylor J. , Wolf Richard , Herringa Ryan J. 
Published: January 2021

AbstractDespite broad evidence suggesting that adversity-exposed youth experience an impaired ability to recognize emotion in others, the underlying biological mechanisms remains elusive. This study uses a multimethod approach to target the neurological substrates of this phenomenon in a well-phenotyped sample of youth meeting diagnostic criteria for posttraumatic stress disorder (PTSD). Twenty-one PTSD-afflicted youth and 23 typically developing (TD) controls completed clinical interview schedules, an emotion recognition task with eye-tracking, and an implicit emotion processing task during functional magnetic resonance imaging )fMRI). PTSD was associated with decreased accuracy in identification of angry, disgust, and neutral faces as compared to TD youth. Of note, these impairments occurred despite the normal deployment of visual attention in youth with PTSD relative to TD youth. Correlation with a related fMRI task revealed a group by accuracy interaction for amygdala–hippocampus functional connectivity (FC) for angry expressions, where TD youth showed a positive relationship between anger accuracy and amygdala–hippocampus FC; this relationship was reversed in youth with PTSD. These findings are a novel characterization of impaired threat recognition within a well-phenotyped population of severe pediatric PTSD. Further, the differential amygdala–hippocampus FC identified in youth with PTSD may imply aberrant efficiency of emotional contextualization circuits.
Increasing secure base script knowledge among parents with Attachment and Biobehavioral Catch-up
Authors: Raby K. Lee , Waters Theodore E. A. , Tabachnick Alexandra R. , Zajac Lindsay , Dozier Mary 
Published: January 2021

AbstractThis study evaluated whether Attachment and Biobehavioral Catch-up (ABC), a parenting intervention, altered the attachment representations of parents (average age of 34.2 years) who had been referred to Child Protective Services (CPS) due to risk for child maltreatment when their children were infants. Approximately 7 years after completing the intervention, parents who had been randomized to receive ABC (n = 43) exhibited greater secure base script knowledge than parents who had been randomized to receive a control intervention (n = 51). Low-risk parents (n = 79) exhibited greater secure base script knowledge than CPS-referred parents who had received a control intervention. However, levels of secure base script knowledge did not differ between low-risk parents and CPS-referred parents who had received the ABC intervention. In addition, secure base script knowledge was positively associated with parental sensitivity during interactions with their 8-year-old children among low-risk and CPS-referred parents. Mediational analyses supported the idea that the ABC intervention enhanced parents’ sensitivity 7 years later indirectly via increases in parents’ secure base script knowledge.
Advantages of a Multi‐Frequency Experiment for Determining the Dielectric Constant of a Layer in a Rectangular Waveguide and Free Space
Authors: Sheina E. A. , Shestopalov Y. V. , Smirnov A. P. 
Published: January 2021

AbstractAn inverse problem of reconstructing real permittivity of a plane‐parallel layer in a perfectly conducting rectangular waveguide or in free space from experimental data using an explicit expression for the scattering matrix is considered. In general, this problem is improperly posed and may be unsolvable due to inaccuracy of the experimental data, and for a perfect noiseless experiment the solution may be not unique because the scattering coefficients curve has self‐intersection points. It is shown that the traditional multi‐frequency method of measurements applied in vector network analyzers can be justified. The following facts are rigorously proved in the paper: nonuniqueness of the solution can be removed if the frequency resolution is sufficiently small; and an algorithm for processing measurement results using least squares provides an approximate solution to the problem that converges to the exact one when the quality of the experiment improves, the convergence rate depends on the number of frequencies used in the experiment.
Laser particles with omnidirectional emission for cell tracking
Authors: Tang Shui-Jing , Dannenberg Paul H. , Liapis Andreas C. , Martino Nicola , Zhuo Yue , Xiao Yun-Feng , Yun Seok-Hyun 
Published: January 2021

AbstractThe ability to track individual cells in space over time is crucial to analyzing heterogeneous cell populations. Recently, microlaser particles have emerged as unique optical probes for massively multiplexed single-cell tagging. However, the microlaser far-field emission is inherently direction-dependent, which causes strong intensity fluctuations when the orientation of the particle varies randomly inside cells. Here, we demonstrate a general solution based on the incorporation of nanoscale light scatterers into microlasers. Two schemes are developed by introducing either boundary defects or a scattering layer into microdisk lasers. The resulting laser output is omnidirectional, with the minimum-to-maximum ratio of the angle-dependent intensity improving from 0.007 (−24 dB) to > 0.23 (−6 dB). After transfer into live cells in vitro, the omnidirectional laser particles within moving cells could be tracked continuously with high signal-to-noise ratios for 2 h, while conventional microlasers exhibited frequent signal loss causing tracking failure.
Creating Majorana modes from segmented Fermi surface
Authors: Papaj Michał , Fu Liang 
Published: January 2021

AbstractMajorana bound states provide a fertile ground for both investigation of fundamental phenomena as well as for applications in quantum computation. However, despite enormous experimental and theoretical efforts, the currently available Majorana platforms suffer from a multitude of issues that prevent full realization of their potential. Therefore, improved Majorana systems are still highly sought after. Here we present a platform for creating Majorana bound states from 2D gapless superconducting state in spin-helical systems under the in-plane magnetic or Zeeman field. Topological 1D channels are formed by quantum confinement of quasiparticles via Andreev reflection from the surrounding fully gapped superconducting region. Our proposal can be realized using narrow strips of magnetic insulators on top of proximitized 3D topological insulators. This setup has key advantages that include: small required fields, no necessity of fine-tuning of chemical potential, removal of the low-energy detrimental states, and large attainable topological gap.
Distilling nanoscale heterogeneity of amorphous silicon using tip-enhanced Raman spectroscopy (TERS) via multiresolution manifold learning
Authors: Yang Guang , Li Xin , Cheng Yongqiang , Wang Mingchao , Ma Dong , Sokolov Alexei P. , Kalinin Sergei V. , Veith Gabriel M. , Nanda Jagjit 
Published: January 2021

AbstractAccurately identifying the local structural heterogeneity of complex, disordered amorphous materials such as amorphous silicon is crucial for accelerating technology development. However, short-range atomic ordering quantification and nanoscale spatial resolution over a large area on a-Si have remained major challenges and practically unexplored. We resolve phonon vibrational modes of a-Si at a lateral resolution of <60 nm by tip-enhanced Raman spectroscopy. To project the high dimensional TERS imaging to a two-dimensional manifold space and categorize amorphous silicon structure, we developed a multiresolution manifold learning algorithm. It allows for quantifying average Si-Si distortion angle and the strain free energy at nanoscale without a human-specified physical threshold. The multiresolution feature of the multiresolution manifold learning allows for distilling local defects of ultra-low abundance (< 0.3%), presenting a new Raman mode at finer resolution grids. This work promises a general paradigm of resolving nanoscale structural heterogeneity and updating domain knowledge for highly disordered materials.
Non-equilibrium metal oxides via reconversion chemistry in lithium-ion batteries
Authors: Hua Xiao , Allan Phoebe K. , Gong Chen , Chater Philip A. , Schmidt Ella M. , Geddes Harry S. , Robertson Alex W. , Bruce Peter G. , Goodwin Andrew L. 
Published: January 2021

AbstractBinary metal oxides are attractive anode materials for lithium-ion batteries. Despite sustained effort into nanomaterials synthesis and understanding the initial discharge mechanism, the fundamental chemistry underpinning the charge and subsequent cycles—thus the reversible capacity—remains poorly understood. Here, we use in operando X-ray pair distribution function analysis combining with our recently developed analytical approach employing Metropolis Monte Carlo simulations and non-negative matrix factorisation to study the charge reaction thermodynamics of a series of Fe- and Mn-oxides. As opposed to the commonly believed conversion chemistry forming rocksalt FeO and MnO, we reveal the two oxide series topotactically transform into non-native body-centred cubic FeO and zincblende MnO via displacement-like reactions whose kinetics are governed by the mobility differences between displaced species. These renewed mechanistic insights suggest avenues for the future design of metal oxide materials as well as new material synthesis routes using electrochemically-assisted methods.
Structural insights into the disruption of TNF-TNFR1 signalling by small molecules stabilising a distorted TNF
Authors: McMillan David , Martinez-Fleites Carlos , Porter John , Fox David , Davis Rachel , Mori Prashant , Ceska Tom , Carrington Bruce , Lawson Alastair , Bourne Tim , O’Connell James 
Published: January 2021

AbstractTumour necrosis factor (TNF) is a trimeric protein which signals through two membrane receptors, TNFR1 and TNFR2. Previously, we identified small molecules that inhibit human TNF by stabilising a distorted trimer and reduce the number of receptors bound to TNF from three to two. Here we present a biochemical and structural characterisation of the small molecule-stabilised TNF-TNFR1 complex, providing insights into how a distorted TNF trimer can alter signalling function. We demonstrate that the inhibitors reduce the binding affinity of TNF to the third TNFR1 molecule. In support of this, we show by X-ray crystallography that the inhibitor-bound, distorted, TNF trimer forms a complex with a dimer of TNFR1 molecules. This observation, along with data from a solution-based network assembly assay, leads us to suggest a model for TNF signalling based on TNF-TNFR1 clusters, which are disrupted by small molecule inhibitors.
Nonequilibrium dynamics of spontaneous symmetry breaking into a hidden state of charge-density wave
Authors: Zhou Faran , Williams Joseph , Sun Shuaishuai , Malliakas Christos D. , Kanatzidis Mercouri G. , Kemper Alexander F. , Ruan Chong-Yu 
Published: January 2021

AbstractNonequilibrium phase transitions play a pivotal role in broad physical contexts, from condensed matter to cosmology. Tracking the formation of nonequilibrium phases in condensed matter requires a resolution of the long-range cooperativity on ultra-short timescales. Here, we study the spontaneous transformation of a charge-density wave in CeTe3 from a stripe order into a bi-directional state inaccessible thermodynamically but is induced by intense laser pulses. With ≈100 fs resolution coherent electron diffraction, we capture the entire course of this transformation and show self-organization that defines a nonthermal critical point, unveiling the nonequilibrium energy landscape. We discuss the generation of instabilities by a swift interaction quench that changes the system symmetry preference, and the phase ordering dynamics orchestrated over a nonadiabatic timescale to allow new order parameter fluctuations to gain long-range correlations. Remarkably, the subsequent thermalization locks the remnants of the transient order into longer-lived topological defects for more than 2 ns.
A binding protein regulates myosin-7a dimerization and actin bundle assembly
Authors: Liu Rong , Billington Neil , Yang Yi , Bond Charles , Hong Amy , Siththanandan Verl , Takagi Yasuharu , Sellers James R. 
Published: January 2021

AbstractMyosin-7a, despite being monomeric in isolation, plays roles in organizing actin-based cell protrusions such as filopodia, microvilli and stereocilia, as well as transporting cargoes within them. Here, we identify a binding protein for Drosophila myosin-7a termed M7BP, and describe how M7BP assembles myosin-7a into a motile complex that enables cargo translocation and actin cytoskeletal remodeling. M7BP binds to the autoinhibitory tail of myosin-7a, extending the molecule and activating its ATPase activity. Single-molecule reconstitution show that M7BP enables robust motility by complexing with myosin-7a as 2:2 translocation dimers in an actin-regulated manner. Meanwhile, M7BP tethers actin, enhancing complex’s processivity and driving actin-filament alignment during processive runs. Finally, we show that myosin-7a-M7BP complex assembles actin bundles and filopodia-like protrusions while migrating along them in living cells. Together, these findings provide insights into the mechanisms by which myosin-7a functions in actin protrusions.
Defect-driven selective metal oxidation at atomic scale
Authors: Zhu Qi , Pan Zhiliang , Zhao Zhiyu , Cao Guang , Luo Langli , Ni Chaolun , Wei Hua , Zhang Ze , Sansoz Frederic , Wang Jiangwei 
Published: January 2021

AbstractNanoscale materials modified by crystal defects exhibit significantly different behaviours upon chemical reactions such as oxidation, catalysis, lithiation and epitaxial growth. However, unveiling the exact defect-controlled reaction dynamics (e.g. oxidation) at atomic scale remains a challenge for applications. Here, using in situ high-resolution transmission electron microscopy and first-principles calculations, we reveal the dynamics of a general site-selective oxidation behaviour in nanotwinned silver and palladium driven by individual stacking-faults and twin boundaries. The coherent planar defects crossing the surface exhibit the highest oxygen binding energies, leading to preferential nucleation of oxides at these intersections. Planar-fault mediated diffusion of oxygen atoms is shown to catalyse subsequent layer-by-layer inward oxide growth via atomic steps migrating on the oxide-metal interface. These findings provide an atomistic visualization of the complex reaction dynamics controlled by planar defects in metallic nanostructures, which could enable the modification of physiochemical performances in nanomaterials through defect engineering.
Nanoscale characterization of the biomolecular corona by cryo-electron microscopy, cryo-electron tomography, and image simulation
Authors: Sheibani Sara , Basu Kaustuv , Farnudi Ali , Ashkarran Aliakbar , Ichikawa Muneyoshi , Presley John F. , Bui Khanh Huy , Ejtehadi Mohammad Reza , Vali Hojatollah , Mahmoudi Morteza 
Published: January 2021

AbstractThe biological identity of nanoparticles (NPs) is established by their interactions with a wide range of biomolecules around their surfaces after exposure to biological media. Understanding the true nature of the biomolecular corona (BC) in its native state is, therefore, essential for its safe and efficient application in clinical settings. The fundamental challenge is to visualize the biomolecules within the corona and their relationship/association to the surface of the NPs. Using a synergistic application of cryo-electron microscopy, cryo-electron tomography, and three-dimensional reconstruction, we revealed the unique morphological details of the biomolecules and their distribution/association with the surface of polystyrene NPs at a nanoscale resolution. The analysis of the BC at a single NP level and its variability among NPs in the same sample, and the discovery of the presence of nonspecific biomolecules in plasma residues, enable more precise characterization of NPs, improving predictions of their safety and efficacies.
Dynamic patterns of YAP1 expression and cellular localization in the developing and injured utricle
Authors: Borse Vikrant , Barton Matthew , Arndt Harry , Kaur Tejbeer , Warchol Mark E. 
Published: January 2021

AbstractThe Hippo signaling pathway is a key regulator of tissue development and regeneration. Activation of the Hippo pathway leads to nuclear translocation of the YAP1 transcriptional coactivator, resulting in changes in gene expression and cell cycle entry. Recent studies have demonstrated the nuclear translocation of YAP1 during the development of the sensory organs of the inner ear, but the possible role of YAP1 in sensory regeneration of the inner ear is unclear. The present study characterized the cellular localization of YAP1 in the utricles of mice and chicks, both under normal conditions and after HC injury. During neonatal development, YAP1 expression was observed in the cytoplasm of supporting cells, and was transiently expressed in the cytoplasm of some differentiating hair cells. We also observed temporary nuclear translocation of YAP1 in supporting cells of the mouse utricle after short periods in organotypic culture. However, little or no nuclear translocation of YAP1 was observed in the utricles of neonatal or mature mice after ototoxic injury. In contrast, substantial YAP1 nuclear translocation was observed in the chicken utricle after streptomycin treatment in vitro and in vivo. Together, these data suggest that differences in YAP1 signaling may partially account for the differing regenerative abilities of the avian vs. mammalian inner ear.