bluuebunny/crossref_metadata_2025_split huggingface dataset:
Third ventricle colloid cysts: An endoscopic case series emphasizing technical variations
Authors: Zymberg Samuel Tau , Riechelmann Guilherme Salemi , da Costa Marcos Devanir Silva , Ramalho Clauder Oliveira , Cavalheiro Sergio 
Published: July 2021

Background:
Colloid cyst treatment with purely endoscopic surgery is considered to be safe and effective. Complete capsule removal for gross total resection is usually recommended to prevent recurrence but may not always be safely feasible. Our objective was to assess the results of endoscopic surgery using mainly aspiration and coagulation without complete capsule resection and discuss the rationale for the procedure.

Methods:
A retrospective review was conducted of 45 consecutive symptomatic patients with third ventricle colloid cysts that were surgically treated with purely endoscopic surgery from 1997 to 2018.

Results:
Mean age was 35.4 years. Male-to-female ratio was 1:1. Clinical presentation included predominantly headache (80%). Transforaminal was the most used route (71.1%) followed by transeptal (24.5%) and interforniceal (4.4%). Capsule was intentionally not removed in 42 patients (93.3%) and cyst remnants were absent on postoperative MRI in 36 (85%). Mild complications occurred in 8 patients (17.8%). Surgery was statistically associated with cyst volume and ventricular size reduction. There were no serious complications, shunts or deaths. Follow-up did not show any recurrence or remnant growth that needed further treatment.

Conclusion:
Gross total resection may not be the main objective for every situation. Subtotal resection without capsule removal seems to be safer while preserving good results, especially in a limited resource environment. Remnants left behind should be followed but tend to remain clinically asymptomatic for the most part. Surgical planning allows the surgeon to choose among the different resection routes and techniques available. Decisions are predominantly based on preoperative imaging and intraoperative findings.
Cytokines, brain proteins, and growth factors in acute stroke patients: A pilot study
Authors: Zafar Atif , Farooqui Mudassir , Ikram Asad , Suriya Sajid , Kempuraj Duraisamy , Khan Mohammad , Tasneem Nudrat , Qaryouti Dania , Quadri Syed , Adams Harold P. , Ortega-Gutierrez Santiago , Leira Enrique , Zaheer Asgar 
Published: July 2021

Background:Immunomodulation and cell signaling involve several cytokines, proteins, and other mediators released in response to the trauma, inflammation, or other insults to the central nervous system. This pilot study is part of the registry designed to evaluate the temporal trends among these molecules after an acute ischemic stroke (AIS) in patients.Methods:Twelve AIS patients were enrolled within 24 hours of the symptoms onset. Two sets of plasma samples were collected: First at admission and second at 24 hours after admission. Cytokines/chemokines and other inflammatory molecules were measured using multiplex assay kit.Results:An increased trend in IL-6 (22 vs. 34 pg/ml), IL-8/CXCL8 (87 vs. 98 pg/ml), MMP-9 (16225 vs. 18450 pg/ml), and GMF-β (999 vs. 3739 pg/ml) levels was observed overtime after an AIS. Patients ≤60 years had lower levels of plasma MCP-1/CCL2 (50–647 vs. 150–1159 pg/ml), IL-6 (9–25 vs. 20–68 pg/ml), and IL-8 (30– 143 vs. 72–630 pg/ml), when compared with patients >60 years old.Conclusion:Cytokines/chemokines and other inflammatory mediators play an important role in the pathogenesis of stroke in addition to mediating poststroke inflammation. Further research is needed to evaluate and characterize the cumulative trends of these mediators for the clinical prognosis or as surrogate biomarkers.
Waste not, want not: Report of a completely calcified C1-C2 juxtafacet cyst and literature review
Authors: Ruggeri Luca , Brunasso Lara , Urrico Giovanni , Alessandrello Raffaele , Cinquemani Giovanni , Lipani Rita , Mandelli Jaime , Nobile Francesco , Iacopino Domenico Gerardo , Maugeri Rosario 
Published: July 2021

Background:
Calcified juxtafacet cysts in the cervical spine are extremely rate. Such symptomatic cysts commonly cause neck pain, radiculopathy, or even myelopathy. MR and CT studies typically document cord/ root compression. On occasion, some of these cysts will spontaneously regress, while many others may warrant surgical removal.

Case Description:
A 70-year-old male presented with a 2-year history of a progressive tetraparesis. The preoperative MR/CT studies showed a C1-C2 left extradural mass occupying more than half of the spinal canal. On MR, it was homogeneously hypointense on both T1- and T2-weighted images, while the CT showed a calcified cyst. Intraoperative and histopathological findings documented a calcified cervical juxtafacet cyst (i.e. ganglion subtype) that was fully excised without sequelae.

Conclusion:
C1-C2 juxtafacet cervical cyst should be considered when a patient presents with myelopathy due to a calcified MR/CT documented paraspinal lesion contributing to significant cervical cord/root compression.
Repercussion of piperine on pharmacokinetics parameters of eletriptan in albino rats: Involvement of CYP3A and P-GP inhibition
Authors: Hematheerthani N  , Siva Reddy CH  , Prameela Rani A  , Suresh Kumar P  
Published: July 2021

Eletriptan is at the type of triptan medication suggested for the management of episodes of severe headache with or without aura. Piperine (1-piperoylpiperidine) is a pure alkaloid as well as the basic tanginess material from the pipli and peppercorn. There are signs that piperine inhibits Cytochrome P-450 enzymes and P-glycoprotein, rather than arouses, drug metabolism generally, thus increasing the bioavailability and effect of several medications. The analysis was undertaken to assess the results of Piperine on the pharmacokinetics of Eletriptan. Samples of blood were taken at different time points for example 0 (predose), 0.5, 1.0, 1.5, 2.0, 2.5, 3.0, 3.5, 4.0, 6.0, 8.0, 12, 24 hours post-treatment. The plasma concentration of Eletriptan was estimated with the HPLC procedure. In our study Cmax, Tmax, AUC0-24 , AUC0-8, AUC%, AUMC0-24, AUMC0-8, t1/2, MRT0-24, MRT0-8 and Volume of distribution were increased by approximately 51.76%, 7.55%, 72.93%, 84.42%, 42.72%, 93.56%, 128.82%, 19.97%, 11.74%, 23.96% and 3% respectively, where as clearance decreased by 42.10% when eletriptan co-administered with piperine. In summary, the results obtained herein imply that Piperine is improving the bioavailability of Eletriptan by strengthening the exposure (AUC) of their Eletriptan when concomitantly administered by the oral route. The Piperine improved the oral bioavailability of eletriptan by inhibiting CYP3A and P-GP in rats. This observation indicates the possibility that the combo of piperine along with other CYP3A and P-GP double substrates can also enhance bioavailability.
A NEW HYBRID PRP-MMSIS CONJUGATE GRADIENT METHOD AND ITS APPLICATION IN PORTOFOLIO SELECTION
Authors: Devila Sindy , Malik Maulana , Giyarti Wed 
Published: July 2021

In this paper, we propose a new hybrid coefficient of conjugate gradient method (CG) for solving unconstrained optimization model. The new coefficient is combination of part the MMSIS (Malik et.al, 2020) and PRP (Polak, Ribi'ere \& Polyak, 1969) coefficients. Under exact line search, the search direction of new method satisfies the sufficient descent condition and based on certain assumption, we establish the global convergence properties. Using some test functions, numerical results show that the proposed method is more efficient than MMSIS method. Besides, the new method can be used to solve problem in minimizing portfolio selection risk .
The influence of media on investment decisions. The case of bubbles
Authors: Perramon Ayza Joaquim 
Published: July 2021

Keywords: bubbles, financial press, investment, mediaAbstract. We analyzed how information in the financial press influences investment decisions and the specific case of economic bubbles. We found considerable flaws in the information market due to several factors: demand, the predominance of what are termed “irrational investors” (herding), and supply, which has the problem that the sources of information are biased and feeds back. A financial bubble is a deviation between real value of a financial asset and its persistent market price in time, which also has a speculative origin fed back by the illusion of the owners of these financial values, who will take benefits because of the future prices, which must be higher than the previous ones. In this context, the economical information in the media is submitting three problems. First of all, it is information generated by companies. In second place, the information circuit is fed back. A problem of informative independence becomes created, particularly serious in the case of the banks, which are at the same time creditors. And in a third place, some informative biases are manifested for the companies of regulated sectors which are starring the economical information in the media.Palabras clave: burbujas, inversiones, medios de comunicación, prensa financieraResumen. El artículo trata como la información en la prensa económica inluencia las decisiones de inversión y del caso específico de las burbujas financieras. Econtramos considerables fallos en el mercado de la información causados por diversos factores: una demanda en la que predomina la denominada inversión irracional (herding) y una oferta en la que las fuentes de información estan sesgadas y se retroalimentan.Una burbuja financiera es una desviación entre el valor real de un activo financiero y su cotización bursátil que tiene un origen especulativo retroalimentado por la ilusión de los propietarios de dichos activos financieros de obtener beneficios esperando que los precios futuros serán mayores a los presentes. En este contexto, la información económica en los medios de comunicación presenta tres problemas.La primera és que la información la generan las propias sociedades. En segundo lugar, el circuito de la información se retroalimenta. Se crea un problema de independencia de la información que resulta particularmente grave en el caso de los bancos que son al mismo tiempo acreedores de las sociedades. Y en tercer lugar algunos sesgos informativos corresponden a empresas de sectores regulados que manifiestan una tendencia a protagonizar la información económica en los medios.
Integración de organizaciones y empresas al territorio por medio de innovaciones sociales
Authors: Portales Luis 
Published: July 2021

Abstract. Territory is a concept that has been approached from different scopes of social sciences. As a result of its study, currently is understand as a multidimensional and complex form, where not only take into consideration the geographical aspect and availability of resources, but also includes a relational and dynamic aspect. Consequence of this view it can be used as a framework to analyze the different connections that social actors presents between them, and the causes, implications and effects they have on the territory where theyoperate. The aim of this paper is to present how different actors have been integrated into the territory as a result of the breakdown in social roles that state, civil society and companies traditionally had been doing. These schemes of collaboration and integration can be understood as social innovations that generate socioeconomic processes aimed to improving living conditions for all inhabitants. The analysis is a framework that serves as the basis for thestudy of social innovations that occur most frequently in the current context.Key words: enterprise integration, inter-sectorial partnerships, social actors, social innovation, territory.JEL: O35, O10, M10Resumen. El territorio es un concepto que ha sido abordado desde diferentes ramas de las ciencias sociales, sin embargo, y como resultado de su estudio, actualmente es visualizado de una forma multidimensional y compleja, en donde no solamente se toman en consideración su aspecto geográfico y la disposición de recursos, sino que también se incluye su aspecto relacional y dinámico. Consecuencia de esta visualización éste puede ser utilizado como un marco de referencia para analizar las diferentes articulaciones que presentan losactores sociales que en él convergen, así como las causas, implicaciones y efectos que éstastienen en el entorno donde se encuentran y en los mismos actores que las generan. El objetivo de este trabajo es presentar la forma en que los diferentes actores se han idointegrando al territorio como consecuencia de la ruptura en los roles sociales que Estado,organizaciones de la sociedad civil y empresas tradicionalmente venían realizando. Estos esquemas de colaboración e integración pueden ser entendidos como innovaciones sociales que generan procesos socioeconómicos orientados a la mejora de condiciones de vida detodos los habitantes. El análisis realizado es un marco de referencia que sirve como base para el estudio de las innovaciones sociales que se presentan con mayor frecuencia en elcontexto actual. Palabras clave: actores sociales, alianzas intersectoriales, innovación social, integración empresarial, territorio.
Revision del proceso de la administracion estrategica, estudio del paradigma de estrategia, estructura y equifinalidad: una investigacion empirica en empresas en noreste de México
Authors: Aguirre H , Flores O , Alatorre V F 
Published: July 2021

Palabras claves: Caos, estrategia, estructura, equifinalidad, , situacional, sistemasResumen. Esta investigación busca comprobar empíricamente el paradigma entre estrategiaestructura y equifinalidad en empresas del noreste de México. Se llevó al cabo un estudio a través de la aplicación de cuestionarios a negocios de esa parte del país. Se consideró como variable independiente la existencia del modelo de Chandler acerca de que la “estructura organizacional sigue a la estrategia”. La variable dependiente, se establece como la obtención de resultados equifinales (igualmente finales), con o sin la existencia del paradigma de estrategia-estructura. Dos contribuciones emergen de este estudio. La primera consiste en haber encontrado que efectivamente existe una relación entre estrategia y estructura en las empresas investigadas. La segunda, y más importante, es que se evidenció, con prueba empírica, el paradigma de equifinalidad. Se necesita mayor investigación para poder determinar las razones para el funcionamiento de este paradigma. La naturaleza holística de la Administración Estratégica puede ser la que explique el éxito final, “sin importar los inicios”.Key words: Chaos, equifinality, situational, strategy, structure, systemAbstract. The objective of this research is to test empirically the strategy, structure and equifinality paradigm in northeast México companies. Businesses, in this region of the country, were studied through the application of a questionnaire. The paradigm of Chandler regarding “structure follows strategy” is the independent variable. The dependent variable is established as finding equifinal results with or without the presence of the strategy -structure paradigm. From this study, two contributions materialize. The first one is that it is effectively true the relationship between strategy and structure. The second and more important one is that the equifinality paradigm was in fact true and empirical evidence was obtained. To determine the reasons for the functioning of this paradigm, more research is needed. “No matter the beginnings”, final success may be explained by the wholistic nature of management.
Identificación de conglomerados (clusters) para implementar objetos de software
Authors: Prieto de Hoyos Manuel 
Published: July 2021

Abstract: This work presents a study about an entrepreneurial information commercial system which identifies data clusters which allow recognizing software objects that may be implemented in a entrepreneur framework. This study proposes a classification attending the function of the objects, normality tests are conducted over the data in order to proof the data clusters existence. Finally new steps in the research are suggested to develop the objectsfound. Key Words: Applications, classification, clusters, functionality, objects, software, statisticResumen. Se presenta un estudio de un sistema de información comercial empresarial para identificar conglomerados de datos que permiten reconocer objetos de software los cuales pueden implementarse en un framework empresarial. El estudio propone una clasificación funcional de los objetos y se llevan a cabo pruebas de normalidad sobre los datos para comprobar la existencia de los conglomerados. Finalmente se sugieren nuevas etapas en lainvestigación para el desarrollo de los objetos resultantes.Palabras Clave: Aplicaciones, clasificación, conglomerados, estadísticas, funcionalidad, objetos, software
Соотношение формальности, неформальности, вежливости, невежливости и грубости с позиции прагматики и дискурс-анализа
Authors: Larina Tatiana V. 
Published: July 2021

Теория вежливости и невежливости является в настоящее время одним из актуальных междисциплинарных направлений исследований, развивающихся на стыке лингвопрагматики, социолингвистики, психолингвистики, дискурс-анализа, когнитивной лингвистики и теории коммуникации. Междисциплинарный подход к изучению категорий вежливости и невежливости позволил по-новому посмотреть на их функционирование и роль в коммуникации, а также проследить их связь со смежными явлениями. Цель статьи — уточнить соотношение вежливости, невежливости, формальности, неформальности и грубости, рассматриваемых в дискурсивно-прагматическом ракурсе, охарактеризовать типы не/вежливости и их функции. Показана необходимость рассматривать вежливость и невежливость на прагматическом уровне с учетом контекста и восприятия высказывания адресатом. С использованием иллюстративных примеров из русского, английского и испанского языков обосновывается необходимость различать вежливость и формальность, невежливость и грубость, поскольку между ними нет полного соответствия. РЕЗЮМЕ Теория вежливости и невежливости является в настоящее время одним из актуальных междисциплинарных направлений исследований, развивающихся на стыке лингвопрагматики, социолингвистики, психолингвистики, дискурс-анализа, когнитивной лингвистики и теории коммуникации. Междисциплинарный подход к изучению категорий не/вежливости позволил по-новому посмотреть на их функционирование и роль в коммуникации. Цель статьи – уточнить некоторые вопросы, касающиеся взаимоотношений вежливости, невежливости, формальности, неформальности и грубости, рассматриваемых в дискурсивно-прагматическом ракурсе, охарактеризовать типы не/вежливости и их функции. Показана необходимость различать вежливость и невежливость на семантическом и прагматическом уровнях с учетом контекста и восприятия высказывания адресатом. С использованием иллюстративных примеров из русского, английского и испанского языков обосновывается необходимость различать понятия «вежливость» и «формальность», «невежливость» и «грубость», поскольку между ними нет полного соответствия.
PENGARUH FAKTOR KELEMBAGAAN, FISIK DAN EKSTERNAL TERHADAP PRODUKTIVITAS BONGKAR MUAT PETIKEMAS
Authors: Marzuki Sumarzen 
Published: July 2021

Loading and unloading container productivity is basically important, because it is support enter and exit of a ship successfully. Cost, time affectivity which is appear during loading and unloading container is give an influence to the efficiency and affectivity in every work. Productivity in a container harbor becomes a work measurement in a container harbor which has correlation in a complexity to take a responsibility in a long period.This observation and analysis started with collected data by responder high value level and low value level in two research places. The observation and analysis bagan with collecting the high level value and low level value data from tow different location, PT. TPS and PT. JICT.The objective of this search are, (1) To estimate the institutional factor regarding the productivity of the loading and unloading container activity; (2) To estimate and analyze the physical factor which consist of the container yard, equipments, gates berth, vessels, and labor regarding the productivity loading and unloading container; (3) To study and analyze the external factors such as economic macro factor and weather factor; (4) study the correlation between the three factors in loading and unloading productivity; (5) In addition to measure differences of worker productivity high and low value level in container both of container proses loading anf unloading terminal is intended.Data which are derived from this search are cross section and time series, which is collected from primary data which allocated a questions sheet to 287 respondents and secondary data which is revelvant and have a correlation with this research.Analysis techniques that applied in this research are Confirmatory Factor Analysis and Full Model from Structural Equation Model (SEM) which is supported by SPSS 14, AMOS 4.01 and MANOVA.There are several result that obtained from this research, (1) Institution have significant effect to container loading and unloading productivity in PT. TPS and PT. JICT; (2) Physical factor which consist of container yard factor, equipments/cranes, gates berth, vessels and labor flow constantly to loading and unloading productivity; (3) The indicator which is derived from external factors mostly does not affect to loading and unloading container productivity; (4) have a strong correlation to container loading and unloading productivity, from the three factors which are shown above; (5) There is no significant difference, between worker on high level stratum as well as on low level in case of handling the productivity of loading anf unloading container activity.Â Keywords:Institutional, physic and external factor, confirmatory factor, Structural Equation Model and MANOVA.
UPAYA MENINGKATKAN PENDAPATAN ASLI DAERAH (PAD) DALAM ERA OTONOMI DAERAH
Authors: Ratnawati Tri 
Published: July 2021

The Action of Local Original Income growth is the growth of local tax and local retribution with some step is optimalization tariff system, growth of tariff, development the object of tax. Local original income can growthed by local asset management with some step is local asset revitalization with exploration local asset potential through value for money added, by local asset management give effect. Multipleer to growth of local original income, the development of SIMBADA, optimalization BUMD and BUMS contribution, optimalization activity of corporate social responsibility.Â Keywords : Â Â Â Local original income, optimalization contribution BUMD and BUMS, asset management
PENGARUH RETURN ON ASSETS (ROA), RETURN ON EQUITY(ROE), NET INTEREST MARGIN (NIM) DAN RASIO BIAYA OPERASIONAL PENDAPATAN OPERASIONAL (BOPO), TERHADAP HARGA SAHAM BANK DI BURSA EFEK INDONESIA.
Authors: Rachmawati Titiek 
Published: July 2021

The purpose of this research is to know the ROA (Return On Assets), ROE (Return On Equity), NIM (Net Interest Margin) and BOPO ratios that influence simultaneously or partially to the shares price in Indonesia Stock Exchange.The research is causal comparative the data resource that were used from bank aunual report 2003 until 2008 from Indonesia Stock exchange . According to the criteria in this research, the samples are 10 banks in industrial banking. For analysing the model and testing the research hypotheses, we used multiple linear regression analysis statistic method. Â Â Â Â Â Â Â Â Â Â Â Based on the research result and the hypotheses test, we can conclude as follow : 1) Â ROA, ROE, NIM and BOPO ratios influence simultaneausly to the shares price. 2) Â ROA, ROE, and BOPO ratios influence partially to the shares price while NIM ratio had proved not influence. Key words : ROA (Return On Assets), ROE ( Return On Equity), NIM ( Net Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Interest Margin), BOPO ratio, shares price.