bluuebunny/crossref_metadata_2025_split huggingface dataset:
Alarm method of communication intelligent manhole cover based on multiple event fusion
Authors: Li Chengfan , Gu Shanming , Guo Gang , Liu Xuefeng , Liu Lan , Zhao Junjuan 
Published: August 2021

AbstractAs a comprehensive utilization of pipeline resources, communication intelligent manhole cover (CIMC) can effectively real-time monitor communication manhole cover and protect the safety of communication pipeline. Due to the complex working environment of manhole cover and the random error of sensor, the traditional monitoring method usual leads to frequent false alarm in actual applications. In order to ensure the monitoring service quality and improve the service efficiency, a new alarm method of CIMC with multiple event fusion in this paper via jointing analysis of multi-sensor status signals is proposed based on the equipment status signals generated by the CIMC terminal and abnormal alarm events definition. The experimental result shows that the proposed CIMC alarm method by means of multiple sensor signals in this paper can not only make up for the defect of a single sensor, but also reduces the false alarm rate caused by the random error of sensor and CIMC system. It can promote the intelligent monitoring efficiency of the manhole cover and be conducive to the construction of intelligent transportation and smart city.
Renewable energy and population growth for sustainable development in the Southeast Asian countries
Authors: Vo Duc Hong , Vo Anh The 
Published: August 2021

AbstractThe energy–environment–growth nexus has been examined for the Association of Southeast Asian Nations (ASEAN) region, mainly using time series data. However, the important role of renewable energy and population has largely been ignored in previous studies. As such, this study is conducted to investigate a causal link between renewable energy usage, population, carbon dioxide emissions, and economic growth. In addition, a relatively new and advanced panel vector autoregressive model and the Granger non-causality test for heterogeneous panels are utilized with a sample of seven ASEAN countries for almost three decades since 1990. Key findings from this paper are as follows. First, renewable energy usage responds to population growth and leads to carbon dioxide (CO2) emissions. Second, economic growth and renewable energy usage explain a substantial proportion of the change in energy consumption. Third, a bidirectional Granger causality does exist in each pair among energy consumption, economic growth and CO2 emissions. We argue that moderating population growth and extending renewable energy usage are vital to achieving sustainable economic growth in the ASEAN region.
Towards more efficient CNN-based surgical tools classification using transfer learning
Authors: Jaafari Jaafar , Douzi Samira , Douzi Khadija , Hssina Badr 
Published: August 2021

AbstractContext-aware system (CAS) is a system that can understand the context of a given situation and either share this context with other systems for their response or respond by itself. In surgery, these systems are intended to assist surgeons enhance the scheduling productivity of operating rooms (OR) and surgical teams, and promote a comprehensive perception and consciousness of the OR. Furthermore, the automated surgical tool classification in medical images is a real-time computerized assistance to the surgeons in conducting different operations. Moreover, deep learning has embroiled in every facet of life due to the availability of large datasets and the emergence of convolutional neural networks (CNN) that have paved the way for the development of different image related processes. The aim of this paper is to resolve the problem of unbalanced data in the publicly available Cholec80 laparoscopy video dataset, using multiple data augmentation techniques. Furthermore, we implement a fine-tuned CNN to tackle the automatic tool detection during a surgery, with prospective use in the teaching field, evaluating surgeons, and surgical quality assessment (SQA). The proposed method is evaluated on a dataset of 80 cholecystectomy videos (Cholec80 dataset). A mean average precision of 93.75% demonstrates the effectiveness of the proposed method, outperforming the other models significantly.
Adjunctive ketamine for sedation in critically ill mechanically ventilated patients: an active-controlled, pilot, feasibility clinical trial
Authors: Amer Marwa , Maghrabi Khalid , Bawazeer Mohammed , Alshaikh Kamel , Shaban Mohammad , Rizwan Muhammad , Amin Rashid , De Vol Edward , Baali Mawadah , Altewerki Malak , Bano Mehreen , Alkhaldi Fawziah , Alenazi Sanaa , Hijazi Mohammed 
Published: August 2021

Abstract
Objective
Ketamine has been shown to decrease sedative requirements in intensive care unit (ICU). Randomized trials are limited on patient-centered outcomes. We designed this pilot trial to evaluate the feasibility of a large randomized controlled trial (RCT) testing the effect of ketamine as an adjunct analgosedative compared with standard of care alone as a control group (CG) in critically ill patients with mechanical ventilation (MV). We also provided preliminary evidence on clinically relevant outcomes to plan a larger trial.

Material and methods
Pilot, active-controlled, open-label RCT was conducted at medical, surgical, and transplant ICUs at a large tertiary and quaternary care medical institution (King Faisal Specialist Hospital and Research Center, Saudi Arabia). The study included adult patients who were intubated within 24 h, expected to require MV for the next calendar day, and had institutional pain and sedation protocol initiated. Patients were randomized in a 1:1 ratio to adjunct ketamine infusion 1–2 μg/kg/min for 48 h or CG alone.

Results
Of 437 patients screened from September 2019 through November 2020, 83 (18.9%) patients were included (43 in CG and 40 in ketamine) and 352 (80.5%) were excluded. Average enrollment rate was 3–4 patients/month. Consent and protocol adherence rates were adequate (89.24% and 76%, respectively). Demographics were balanced between groups. Median MV duration was 7 (interquartile range [IQR] 3–9.25 days) in ketamine and 5 (IQR 2–8 days) in CG. Median VFDs was 19 (IQR 0–24.75 days) in ketamine and 19 (IQR 0–24 days) in the CG (p = 0.70). More patients attained goal Richmond Agitation–Sedation Scale at 24 and 48 h in ketamine (67.5% and 73.5%, respectively) compared with CG (52.4% and 66.7%, respectively). Sedatives and vasopressors cumulative use, and hemodynamic changes were similar. ICU length-of-stay was 12.5 (IQR 6–21.2 days) in ketamine, compared with 12 (IQR 5.5–23 days) in CG. No serious adverse events were observed in either group.

Conclusions
Ketamine as an adjunct analgosedative agent appeared to be feasible and safe with no negative impact on outcomes, including hemodynamics. This pilot RCT identified areas of improvement in study protocol before conducting a large, adequately powered, multicenter RCT which is likely justified to investigate ketamine association with patient-centered outcomes further.
Trial registration ClinicalTrials.gov: NCT04075006. Registered on 30 August 2019. Current controlled trials: ISRCTN14730035. Registered on 3 February 2020
The mobility paradigm in higher education: a phenomenological study on the shift in learning space
Authors: Chattaraj Dishari , Vijayaraghavan Arya Parakkate 
Published: August 2021

AbstractThe study, through the framework of mobility and space, explores the phenomenon of multiple shifts in learning spaces induced by COVID-19. The Interpretative Phenomenological Approach (IPA) is adopted to document the experiences and perceptions of learners caught within these spatial shifts—physical, online, and hybrid. Online interviews were conducted with six first-year undergraduate and three first-year postgraduate students enrolled at the department of English and Cultural Studies in a Southern Indian University. Some of the dominant patterns emerging from the accounts of the participants are (1) the changing perception of conducive learning space, (2) the changing perceptions and roles of various classroom actors, and (3) the evolving nature of the learners and the learning process. The study utilizes the framework of mobility to locate the stage of embodied skill acquisition of the participants within the online learning space and illuminates the possibilities offered by this paradigm within the context of higher education. Some of the insights gained through the study include a changing perception of the conventional built classroom space, a notable preference towards a complete online or offline mode as opposed to the hybrid mode, and a transition towards self-directed learning. The study argues that these implications are highly pertinent and can significantly shape the way pedagogues and researchers engage with the various modes of learning—physical, online, and hybrid—and the future of higher education that is shaped by technology-enabled learning.
Experimental study on improving the accuracy of marine gravimetry by combining moving-base gravimeters with GNSS antenna array
Authors: Shi Zhimin , Lang Junjian , Liang Xinghui , Zhou Zhibo , Guo Aizhi , Liu Lintao 
Published: August 2021

AbstractThe gravity field is one of the Earth’s basic physical fields. The geoid can be calculated and the tectonic activity underground can be inversed by gravity anomaly. With the development of various ship-borne gravimeters and navigation technology, including the Global Navigation Satellite System (GNSS) and Strapdown Inertial Navigation System (SINS), the precision of marine gravimetry has been significantly improved (achieve or better than 1mGal). Errors arising from calculations of the correction term have become the main source of gravity measurement errors. At present, the traditional approach is to deploy a GNSS antenna, connect the GNSS antenna to the gravimeter, record the real-time position through data acquisition software, and then use this position to calculate the gravity correction item afterward. Two errors are inevitable. (1) The GNSS antenna position error is large. The pseudorange point positioning method is generally used to obtain real-time GNSS antenna positions, and the positioning accuracy is poor compared with that of precise point positioning. (2) The position coordinates of the gravimeter contain systematic errors related to the ship’s attitude. In this paper, a joint experiment including GNSS antenna arrays and ship-borne gravimeters was designed to evaluate the measurement accuracy via repeat lines on the same ship. The experimental results show the following: (1) attitude accuracies of 0.0299° for the yaw angle, 0.0361° for the pitch angle, and 0.1671° for the roll angle can be obtained at baseline lengths of 25 and 4 m. (2) The GNSS antenna array has an obvious role in determining the point acceleration in the low-frequency band (0–0.01 Hz) and the point position and velocity in the high-frequency band (0.01–1 Hz). (3) The vertical position eccentricity causes an absolute error of 1 mGal and a relative error of$${10}^{-1}$$10-1mGal in gravity measurements and can be corrected by the GNSS antenna array method. (4) Using a GNSS antenna array can obviously improve the measurement accuracy of an instrument with a precision equaling or exceeding 1 mGal, but cannot obviously improve that to an instrument with poor precision (2 mGal or below).
Vogt-Koyanagi-Harada Syndrome following COVID-19 and ChAdOx1 nCoV-19 (AZD1222) vaccine
Authors: Saraceno Janaína Jamile Ferreira , Souza Guilherme Macedo , dos Santos Finamor Luciana Peixoto , Nascimento Heloisa Moraes , Belfort Rubens 
Published: August 2021

AbstractThe challenge of COVID-19 has rapidly changed medical management worldwide. The relatively small time from pandemic to vaccines regulatory approval triggered a race toward vaccines development. However, important questions regarding SARS-CoV-2 vaccines remain. A case of complete Vogt-Koyanagi-Harada (VKH) Syndrome that occurred 4 days following SARS-CoV-2 vaccination and another patient that developed VKH 14 days post COVID-19 clinical onset are presented. A causal relationship between COVID-19 and uveitis may exist.
How long-term mass rearing affects the quality of the Trichogramma embryophagum (Hartig) (Hymenoptera: Trichogrammatidae) reared on Sitotroga cerealella (Olivier) eggs
Authors: Sadat Farzaneh , Nazari Alireza , Jafari Shahriar , Karahroudi Zahra Rafiei 
Published: August 2021

AbstractBackgroundMaintaining the quality and efficacy of biological control agents during long-term mass rearing plays a crucial role in the success of a biological control program. In this study, the biological traits of a local population colony ofTrichogramma embryophagum(Hartig) with rearing onSitotroga cerealella(Olivier) eggs for over 40 generations (G) were assessed.ResultsFemale adult longevity was significantly different among generations, ranging from 7.98 d in G5 to 5.19 d in G40. The reared wasps showed highest fecundity (60.50 eggs/female) in G5 compared to the other generations. The female sex ratio varied from 63.16% in G5 to 49.31% in G40. Significant differences were observed in population growth parameters and the highest gross reproductive rate (GRR) (40.96 eggs/individual) and net reproductive rate (R0) (38.21 eggs/individual) were found in G5. However, a non-significant difference was found in the intrinsic rate of natural increase (r) until the 10th generation, but its values significantly declined with increasing the generation numbers. The finite parasitism rate (ω) ranged from 0.468 host/parasitoid/day in G5 to 0.274 host/parasitoid/day in G40.ConclusionsThe results showed that the quality ofT. embryophagumreared under continuous laboratory conditions declined after 10 generations, and for use of them in biological control programs under field conditions, the reared population should be refreshed by adding wild individuals from time to time.
Contemporary approach to understand and manage COVID-19-related arrhythmia
Authors: Nabeh Omnia Azmy , Helaly Maiada Mohamed , Menshawey Rahma , Menshawey Esraa , Nasser Mohammed Mansoor Matooq , Diaa El-deen Ahmed Mohamed 
Published: August 2021

AbstractArrhythmia, one of the most common complications of COVID-19, was reported in nearly one-third of diagnosed COVID-19 patients, with higher prevalence rate among ICU admitted patients. The underlying etiology for arrhythmia in these cases are mostly multifactorial as those patients may suffer from one or more of the following predisposing mechanisms; catecholamine surge, hypoxia, myocarditis, cytokine storm, QTc prolongation, electrolyte disturbance, and pro-arrhythmic drugs usage. Obviously, the risk for arrhythmia and the associated lethal outcome would rise dramatically among patients with preexisting cardiac disease such as myocardial ischemia, heart failure, cardiomyopathy, and hereditary arrhythmias. Considering all of these variables, the management strategy of COVID-19 patients should expand from managing a viral infection and related host immune response to include the prevention of predictable causes for arrhythmia. This may necessitate the need to investigate the role of some drugs that modulate the pathway of arrhythmia generation. Of these drugs, we discuss the potential role of adrenergic antagonists, trimetazidine, ranolazine, and the debatable angiotensin converting enzyme inhibitors drugs. We also recommend monitoring the level of: unbound free fatty acids, serum electrolytes, troponin, and QTc (even in the absence of apparent pro-arrhythmic drug use) as these may be the only indicators for patients at risk for arrhythmic complications.
Design of experiment-driven stability-indicating RP-HPLC method for the determination of tofacitinib in nanoparticles and skin matrix
Authors: Gorantla Srividya , Saha Ranendra N. , Singhvi Gautam 
Published: August 2021

AbstractBackgroundTofacitinib—an oral JAK inhibitor—has been recently approved by US FDA to treat moderate to severe RA. The delivery of tofacitinib to specific inflammation site at joint via topical route using nanoformulations helps in managing the potential adverse effects. The objective is to develop and validate a simple, specific, and sensitive stability-indicating HPLC method for quantification of tofacitinib in topical nanoformulations and different matrices (adhesive tape, and skin layers, i.e., stratum corneum, viable epidermis, and dermis). The major objective was to avoid use of instruments like LC–MS/MS and to ensure a widespread application of the method.ResultA 32factorial ‘design of experiments’ was applied to optimize process variables, to understand the effect of variables on peak properties. The calibration curve showed regression coefficient (R2) 0.9999 and linearity in the concentration range of 50 to 15,000 ng/mL, which is suitable for the analysis of conventional dosage forms and nanoformulations. Method validation was performed as per ICH guideline Q2 (R1). The accuracy by recovery studies ranged between 98.09 and 100.82%. The % relative standard deviations in intraday and interday precisions were in the range of 1.16–1.72 and 1.22–1.80%, respectively. Forced degradation studies indicated the specificity of method and showed stability-indicating potential for tofacitinib peak.ConclusionThe validated method provides a quantification method of tofacitinib in the presence of formulation excipients, dissolution media, and skin tissues in detail. In addition, the method was successfully utilized for determination of various dermatokinetics profile of tofacitinib.
Stability-indicating HPLC-DAD method for the determination of empagliflozin
Authors: Pathak Shilpi , Mishra Pradeep 
Published: August 2021

Abstract
Background
A stability-indicating RP-HPLC method was developed and validated for the estimation of empagliflozin drug and its tablet dosage form using a DAD detector. The mobile phase consisted of methanol/acetonitrile/0.1%OPA (75:20:5). The peak was observed at 2.54 min using 222.0 nm absorption maxima.

Results
Calibration curve plot was found within the range of 10–50 µg/mL. The coefficient of determination (R2) was found to be 0.9990. Forced degradation studies were performed for the empagliflozin in various conditions, and the results were calculated as %RSD values and were found to be within the limits.

Conclusion
The method was validated as per ICH guidelines with respect to all validation parameters.
Impact of Radiation Oncology Alternative Payment Model on Community Cancer Centers
Authors: Meeks Sanford L. , Mathews Ryan , Mojica Jennifer , Shah Amish P. , Kelly Patrick , Dvorak Tomas 
Published: August 2021

PURPOSE: An episode-based payment model, the Radiation Oncology Alternative Payment Model (RO-APM), is scheduled to go into effect in January 2022. This article investigates the effects of RO-APM on hospital-based and freestanding community centers. METHODS: Historical Medicare data used to generate the RO-APM base rates were reviewed. A sensitivity analysis was performed to show how the RO-APM reimbursements compare with current reimbursements for commonly accepted treatment schedules and with current reimbursements at a large community practice. RESULTS: The RO-APM base rates represent a 2.2% decrease in overall Medicare reimbursement. Freestanding centers have historically billed at higher rates than hospital-based centers, however, and the RO-APM base rates represent a 6% decrease in global reimbursement for freestanding centers. The sensitivity analysis showed that, except for proton therapy, moderately hypofractionated treatment schedules will receive comparable reimbursement under RO-APM. Treatments using higher numbers of fractions of intensity-modulated radiation therapy or protons will see larger decreases in reimbursement. Application of the RO-APM base rates to the 2020 Medicare treatments in our health care network would result in small changes in expected reimbursement, but our sensitivity analysis indicated that Medicare reimbursement reductions could be as large as 23%. CONCLUSION: Compared with historical Medicare reimbursement, RO-APM base rates provide lower reimbursement for many common treatment scenarios, and this will have a larger effect on centers that use complex treatment techniques and longer fractionation schedules or have a large Medicare population.
O Espaço das mulheres na pandemia de Covid-19: uma análise entre agência e vulnerabilidade | The place of women in the Covid-19 pandemic: An analysis between agency and vulnerability
Authors: Lattanzi Menezes Eduarda , Aguiar Bruna Soares de 
Published: August 2021

No contexto da pandemia da Covid-19, a Organização Mundial da Saúde orientou que os países restringissem a circulação de pessoas, de modo a evitar a propagação do vírus e criar alternativas para o enfrentamento da doença. A quarentena gerou, em muitos Estados, consequências econômicas e sociais. Considerando os Estados do Sul global, notam-se efeitos em determinados grupos sociais, incluindo as mulheres. Nesse sentido, este artigo questionará sobre o lugar das mulheres na gestão da pandemia, evidenciando a agência feminina na construção de alternativas para as sociedades. Este objetivo será alcançado por meio de uma análise feminista pós-colonial, a partir da aplicação metodológica de estudo de casos sobre três iniciativas de grupos de mulheres do Sul: as “Coronadamas”, no Irã; as mulheres indígenas de Santiago Jocotepec, no México, e o processo de tomada de decisão de mulheres na África Ocidental.Palavras-chave: Coronavírus; Feminismo; Sul Global.ABSTRACTIn the context of the Covid-19 pandemic, the World Health Organization advised that countries restrict the movement of people to prevent the spread of the virus and create alternatives for coping with the disease. Quarantine has had economic and social consequences in many states. Considering the States of the Global South, there are effects on specific social groups, including women. This paper aims to put in the question where the place of women is in the management of the pandemic, highlighting the female agency in the construction of alternatives for societies. This objective will be achieved through a post-colonial feminist analysis, based on the methodological application of case studies on three initiatives by groups of women in the South: the “Coronadamas” in Iran; indigenous women from Santiago Jocotepec, Mexico, and the decision-making process of women in West Africa.Keywords: Coronavirus; Feminism; Global South. Recebido em: 02 abr. 2021 | Aceito em: 07 jun. 2021.
Frequency controlled beam scanning characteristic realized using a compact slow wave transmission line
Authors: Yin Jia-Yuan , Du Xiao Yu , Ning Yuan , Deng Jing-Ya , Guo Li-Xin 
Published: August 2021

To simplify the design of a beam scanning device, we present a simple and compact structure to realize the frequency scanning characteristic based on a hybrid waveguide consisting of a spoof surface plasmon polariton (SSPP) transmission line and half-mode substrate integrated waveguide (HMSIW). Additionally, the radiation characteristic is implemented using periodically modulated slots. The scanning angle range covers backward to forward directions without an open stop band at the broadside. The results from both simulations and measurements show that the total scanning angle reaches 117° for a frequency range of 9–11.4 GHz. Owing to the inherent features of the HMSIW and the unique design of the SSPP transmission line, the entire structure is only

139.2

m
m

×

15

m
m

in size. Moreover, the average gain is approximately 6.5 dBi. Overall, the compact size and good performance ensure that the proposed design is favorable for planar integrated communication systems.