bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluasi Kepatuhan Minum Obat Pasien Diabetes Melitus Tipe 2 Di Fasilitas Kesehatan Tingkat Pertama UPTD Puskesmas Ungaran Dan UPTD Puskesmas Ambarawa Dengan Intervensi Pemberian Home Pharmacy Care
Authors: Hati Anita Kumala , Karminingtyas Sikni Retno , Devi Dita Arisca , Damai Wati Brian Resti 
Published: October 2021

Diabetes Melitus merupakan penyakit kronis dengan pengobatan jangka panjang yang memerlukan kepatuhan. Salah satu intervensi yang komprehensif untuk penyakit DM adalah home pharmacy care untuk meningkatkan kepatuhan pasien. Kepatuhan minum obat pasien Diabetes Melitus yang dilihat dari parameter Modified Morisky’s Adherence Scale (MMAS-8), Gula Darah Puasa (GDP) dan pill count. Penelitian ini bertujuan melihat hasil intervensi Home Pharmacy care terhadap kepatuhan minum obat pasien Diabetes Mellitus tipe 2 di UPTD Puskesmas Ungaran dan UPTD Puskesmas Ambarawa pada periode Mei hingga Juni 2018. Hasil penelitian dengan uji T berpasangan ditinjau dari MMAS-8 didapatkan p value 0,118 pada kelompok kontrol dan 0,000 pada kelompok perlakuan. Sedangkans ditinjau dari GDP didapatkan p value 0,223 pada kelompok kontrol dan 0,000 kelompok perlakuan. Dan dengan uji T tidak berpasangan berdasarkan pill count didapatkan p value 0,000. Maka dapat disimpulkan pemberian home pharmacy care dapat meningkatkan kepatuhan minum obat pasien DM tipe II di UPTD Puskeskmas Ungaran dan UPTD Puskesmas Ambarawa.Kata Kunci : Home pharmacy care, Diabetes Melitus Tipe 2, Kepatuhan.Diabetes Melitus is a chronic disease with long-term treatment that requires adherences. One of the most comprehensive interventions for DM patients is Home Pharmacy Care, that can monitor patient compliance. The study aims to determine the effect of Home Pharmacy Care DM against medication adherence which is seen from the parameter of Modified Morisky’s Adherence Scale (MMAS-8), blood glucose (GDP) and pill count. This research was a quasi experimentpretest-posttest with control group design, the study conducted in Ungaran and Ambarawa public health center from May to Jun 2018. The sampling method was accidental sampling technique. Samples obtained were 62 people and divided into 2 groups of control group (31 people) and treatment group (31 people). The result of paired t-test indicated that p value of control group reviewed by MMAS-8 was 0,118 and treatment group was 0,000. Based p value glucose blood (GDP) of control group was 0,223 and treatment group was 0,000. The result of independentt-test by p value of the pill count was 0,000. Home Pharmacy Care can improve medication adherence to Diabetes Melitus Type II patientsat the Ambarawa public health center. Keywords : Home pharmacy care, Diabetes Melitus Type 2, Adherence.
Skrining Fitokimia Dan Analisis Kromatografi Lapis Tipis Ekstrak Etanol Kulit Buah Naga Merah (Hylocereus polyrhizus)
Authors: Jawa La Elisabeth Oriana , Sawiji Repining Tiyas , Yuliawati Agustina Nila 
Published: October 2021

Buah naga merah (Hylocereus polyrhizus) merupakan tumbuhan yang sudah banyak dimanfaatkan oleh masyarakat Indonesia secara alami sebagai tanaman kaya antioksidan, sebaliknya pemanfaatan dari kulit buah naga merah belum sepenuhnya dimaksimalkan. Beberapa penelitian yang telah dilakukan menunjukkan bahwa selain daging buah, kulit buah naga merah dapat dimanfaatkan sebagai sumber untuk pengobatan karena kaya akan antioksidan. Hal tersebut dapat digunakan sebagai dasar dan pilihan untuk menghasilkan produk obat tradisional dari kulit buah naga merah. Penelitian ini bertujuan untuk mengidentifikasi kandungan metabolit sekunder yang terdapat pada kulit buah naga merah berupa skrining fitokimia dan kromatografi lapis tipis (KLT) pada senyawa aktif yang disinyalir terkandung didalam kulit buah naga merah yang dapat dimanfaatkan dalam produk kefarmasian. Ekstraksi dilakukan dengan cara maserasi menggunakan pelarut etanol 96% diperoleh rendemen ekstrak sebanyak 2,96%. Skrining fitokimia dilakukan sebagai uji pendahuluan untuk mengidentifikasi kandungan metabolit sekunder yang terkandung dalam ekstrak kulit buah naga merah, dilanjutkan dengan KLT untuk mempertegas hasil reaksi positif. Hasil skrining dan KLT diperoleh kulit buah naga merah positif mengandung alkaloid, tanin, flavonoid, steroid dan potensial untuk dijadikan obat tradisional.Kata kunci :kulit buah naga merah, skrining fitokimia, KLT, metabolit sekunder Red dragon fruits (Hylocereus polyrhizus) generally has been widely known Indonesian as a plant that rich in antioxidant however, the Red dragon fruits peel is not fully utilized. Some of studies have been conducted indicating that as well as its fruit flesh, Red dragon fruits peel can be beneficial as a source for treatment and traditional medicinal products since it is also rich of antioxidants.This research aims to identify the content of secondary metabolites on the Red dragon fruits peel in the form of phytochemical screening and thin-layer chromatography (TLC) in the active compounds which can be utilized in the product of Pharmacy. Extraction is conducted by maceration using the 96% ethanol solvent in order to produces extracts as much as 2.96 %. Phytochemical screening is delivered as a preliminary test to identify the content of secondary metabolites contained in the peel of Red dragon fruit peel and continued with the TLC to confirmed give positive results. Results of the screening and TLC obtained that the peel of Red dragon fruits positive contains alkaloids, tannins, flavonoids, steroids and potential to be used as traditional medicineKeyword : Red dragon fruit peel, phytochemical screening, TLC, secondary metabolites
Contribution of social and demographic parameters to the long-term survival prognosis of chronic myeloid leukemia patients
Authors: Kulikov S. M. , Lazareva O. V. , Turkina A. G. , Kulikovsky A. A. , Pospelova T. I. , Kutsev S. I. , Zaritzkey A. Yu. , Shatokhin Yu. V. , Konstantinova T. S. , Parovichnikova E. N. , Savchenko V. G. 
Published: October 2021

Introduction. Therapy of chronic myeloid leukemia (CML) for the majority of patients is associated with continuous lifelong drug intake. Irregular drug intake greatly increases the risk of CML progression and death. It is still not well understood to what extent social and demographic factors infl uence the long-term consequences of CML therapy.Aim — to determine the prognostic value of social parameters like marital status and education level in comparison with standard risk factors for the course of the disease.Materials and methods. A multifactorial data analysis of the presented sociodemographic parameters was carried out on a cohort of CML patients included in the multicenter observational study “Russian Registry for the Treatment of Chronic Myeloid Leukemia in Routine Clinical Practice”. The database of the study conducted in Russia in 2011–2016 includes records of 12160 patients with CML. To analyze the register data, we used classical methods of event analysis implemented in the SAS 9.4 package.Results. A large volume of data with a high level of signifi cance showed that educational level and marital status have a great prognostic value in assessing the long-term results of therapy in patients with CML, comparable to known risk factors. The contribution of these signs was evaluated and analyzed taking into account such known factors as age, ELTS index, and region or clinic where the patient was observed and treated. Thus, low educational qualifi cations and marital status “divorced” or “widowed” demonstrated signifi cant and independent risk factors that negatively affect the life expectancy of patients with CML Conclusion. The discovered phenomenon is key in long-term survival and can be explained by the indirect infl uence of social-demographic parameters through adherence behavior of CML patients. Higher level of education proved to be a favorable factor while a widowed/divorced marital status was found to be an unfavorable factor of OS prognosis. General clinic, age related interpretations, and regional features were also tested and did not fi nd any confi rmation.
Uso excesivo del celular, calidad de sueño y soledad en jóvenes de la ciudad de Arequipa
Authors: Sota Velásquez Atena , Maldonado López Melani , Ytuza Cusirramos Manuel , Cornejo Torres María del Carmen , Cusirramos Carpio Yessenia 
Published: October 2021

Se dice que el uso excesivo de celulares entre adolescentes y jóvenes puede causar efectos negativos en su salud psicológica y física, así como en su calidad de sueño. En diversas investigaciones se menciona que las personas que informan un mayor nivel de soledad también refieren menos sueño. Sin embargo, todavía es necesario profundizar, la relación entre el uso excesivo al celular, la calidad del sueño y la soledad, ya que no existe suficiente evidencia para definirla. Se seleccionó una muestra de 397 estudiantes universitarios de la ciudad de Arequipa, utilizando como criterio de inclusión que cursen
estudios en una universidad y que se encuentren entre el rango de edad de 17 a 25 años. Los estudiantes fueron invitados a completar un cuestionario anónimo que contenían datos demográficos, la Escala de Soledad de la Universidad de California los Ángeles ULS-8, el Índice de Calidad de Sueño de Pittsburgh ICSP y el cuestionario autoadministrable del Uso Problemático del Celular para adolescentes. Se encontró que las variables soledad, calidad del sueño y uso problemático del celular tienen una relación significativa entre sí. Los resultados obtenidos corroboran la hipótesis planteada, encontrando que, sí existe relación entre las variables soledad, calidad del sueño y uso problemático del celular en estudiantes universitarios.
Institution of education as an agent of Russian pensioners’ post-labor adaptation
Authors: Луцькая Е.Е. , Тумакова С.Ю. 
Published: October 2021

тенденция демографического старения населения вынуждает все сферы современного российского общества адаптироваться к увеличению числа лиц старшей возрастной группы. О наличии такой адаптации свидетельствует возникновение во многих регионах РФ различных образовательных программ для людей третьего возраста, где пенсионеры могут изучать иностранные языки, заниматься творчеством и любительским спортом, осваивать компьютер и мобильные устройства. В статье рассмотрены многие проблемы, возникающие после прекращения работы (одиночество, социальная эксклюзия, информационное неравенство, снижение качества жизни и удовлетворенности ею, ухудшение материального положения), которые помогает разрешать образование как социальный институт. Вовлечение старшего поколения в образовательные мероприятия позволит продлить период здоровой, активной жизни, что хотя бы частично снизит нагрузку на систему здравоохранения и медицинской помощи в долгосрочной перспективе. Образовательная инклюзия пенсионеров позволит решить проблему дефицита трудовых ресурсов, связанную с демографическим кризисом (падением рождаемости), привлечь пенсионеров к участию в решении некоторых социально значимых проблем (экологической, адаптации выпускников детдомов, помощь инвалидам, престарелым, людям без определенного места жительства).
tendency of population’s demographic aging challenge all spheres of modern Russian society to adapt to growth of number of elderly people. Appearance of various educational programs for elderly people’s learning foreign language, creation, sports, computer, gadgets, and digital literacy at many Russian regions say about this adaptation. Many problems, appearing after leaving a work (solitude, social exclusion, informational inequality, reducing of quality of life, life satisfaction and incomes), which education as a social institution helping to cope, considered at the article. Involvement older generation in educational arrangement prolong a period of healthy and active life and decrease partly a burden on the system of public health and medical aid. Educational inclusion allows to attract pensioners to participation at decision some social problems, such as ecological problem, problem of social adaptation of children homes’ graduates, aid senile people, disabled and homeless persons and to solve a problem of working resources’ deficit, appearing because of demographic crisis and birth rate reducing.
Formation of a legitimate model of students' behavior in the application of distance education systems
Authors: Сунцова Е.А. , Маркова Н.А. 
Published: October 2021

статья посвящена исследованию конструктивных аспектов процесса формирования правомерной модели поведения обучающихся при применении дистанционных систем образования. Особое внимание уделено проблемам выстраивания и интегрирования правомерной линии поведения и правового воспитания обучающихся путем применения инновационных технологий при дистанционном обучении. В статье сформулированы соответствующие предложения по выработке концепций, программ и методик, направленных на повышение уровня правовых знаний и правопонимания обучающихся при применении дистанционных систем образования.
the article is devoted to the study of constructive aspects of the process of forming a legitimate model of behavior of students in the application of distance education systems. Special attention is paid to the problems of building and integrating a legitimate line of behavior and legal education of students using innovative technologies in the remote format of the educational process. The article formulates appropriate proposals for the development of concepts, programs and methods aimed at improving the level of legal knowledge and legal understanding of students in the application of distance education systems.
Social media in distance learning
Authors: Алексеенко И.В. 
Published: October 2021

в настоящее время социальные сетевые медиа играют заметную роль во всех сферах жизнедеятельности. Они помогают осуществлять социальные стратегии и практики во многих сферах общества, в том числе и в образовании. Пандемия COVID-19 потребовала перехода на дистанционное обучение, к которому активно подключились социальные сети. Все многообразие дистанционнных форм обучения можно разделить на синхронные формы обучения, ассинхронные и смешанные формы. Социальные медиа позволяют сделать дистанционный формат интереснее, вовлекать студентов в дискуссии, усиливать наглядность, использовать игровые практики и изучать практические кейсы.
nowadays social media plays a prominent role in all spheres of life. They help to put into practice social strategies and practices in many aspects of social life, including education. The COVID-19 pandemic has demanded a transition to distance learning, and social networks were positively included in this process. All the variety of distance learning forms can be divided into synchronous forms of learning, asynchronous and hybrid forms. Social media makes it possible for the distance learning to be more interesting, to involve students in discussions, to improve visual teaching methods, to use games practices, and to consider practical cases.
KUALITAS PELAYANAN KARTU PENCARI KERJA DI DINAS TENAGA KERJA, KOPERASI DAN USAHA KECIL MENENGAH KOTA GORONTALO
Authors: Bagou Usan 
Published: October 2021

Penelitian ini bertujuan untuk mengetahui kualitas pelayanan kartu pencari kerja di Dinas Tenaga Kerja, Koperasi dan Usaha Kecil Menengah Kota Gorontalo. Metode penelitian menggunakan jenis deskriptif pendekatan kualitatif. Fokus penelitian ini adalah kecepatan, ketepatan, dan berkeadilan. Teknik pengumpulan data dilakukan melalui wawancara mendalam kepada sejumlah informan, observasi dan pencatatan data sekunder yang berkaitan dengan permasalahan penelitian.
Hasil penelitian menyimpulkan bahwa, pelayanan kartu pencari kerja dengan aspek kecepatan belum berkualitas. Pelayanan kartu pencari kerja dengan aspek ketepatan belum berkualitas. Pelayanan kartu pencari kerja dengan aspek berkeadilan belum berkualitas. Secara keseluruhan dapat disimpulkan bahwa, kualitas pelayanan kartu pencari kerja di Dinas Tenaga Kerja, Koperasi dan Usaha Kecil Menengah Kota Gorontalo belum optimal. Hal tersebut terlihat dari masih lambatnya pelayanan yang diberikan oleh aparat, ketidaksesuain hasil cetakan kartu pencari kerja yang diberikan oleh petugas dengan dokumen asli dari pemohon kartu pencari kerja, serta belum terciptanya pelayanan yang berkeadilan dengan mengedepankan prinsip kesamaan hak.
Disarankan, perlunya meningkatkan responsibilitas aparat Dinas Tenaga Kerja, Koperasi dan Usaha Kecil Menengah Kota Gorontalo dalam rangka memberikan pelayanan yang cepat kepada pemohon kartu pencari kerja. Perlunya meningkatkan keakurasian pelayanan para patugas Dinas Tenaga Kerja, Koperasi dan Usaha Kecil Menengah Kota Gorontalo yang mengacu pada standar operasional prosedur (SOP). Perlunya menumbuhkan rasa tanggung jawab bagi setiap petugas pelayanan untuk selalu memberikan pelayanan dengan prinsip kesamaan hak kepada setiap masyarakat. Perlunya dilakukan upaya penanaman pemahaman kepada para petugas untuk selalu memberikan pelayanan yang cepat, tepat atau akurat dan berkeadilan.
Kata Kunci: Kualitas; Pelayanan; Penerbitan; Kartu Pencari Kerja
Incidental Appendiceal Diverticulosis Associated with Acute Appendicitis: A Case Report and Review of Literature
Authors: Haydar Alaa , Sawaya Zeina , Kaouk Hussein , Elhajj Assem 
Published: October 2021

Background: Appendiceal diverticulum (AD) is a rare surgical finding. This entity is classified as either congenital or acquired, with a reported incidence of 0.014% and 0.2-1.7%, respectively. AD can often be associated with acute or chronic appendicitis. Clinically, AD must be identified before any surgical procedure as its concomitant presence with acute or chronic appendicitis increases the risk of perforation and may be associated with underlying neoplasia such as low-grade mucinous adenoma. We hereby report a case of incidental appendiceal diverticulosis associated with acute appendicitis in an attempt to increase the physicians’ perception, knowledge, and awareness of this rare medical condition.
Case Presentation: We report a 40-year-old male patient, with no relevant family history, who presented to the Emergency Department after four days of vague and moderate epigastric pain and nausea. The physical examination upon presentation was unremarkable. Computed Tomography (CT) scan was done and was suggestive of an inflamed appendix. The patient underwent an urgent laparoscopic appendectomy. The removed appendix was inflamed and grossly abnormal with multiple diverticulae. The patient had a smooth recovery.
Conclusion: Diverticulosis of the appendix is a rare clinical entity and, as in our case, is often diagnosed during or after appendectomy. When associated with acute appendicitis, it may be suspected preoperatively with the appropriate imaging technique. This is of paramount importance as it can rapidly progress to perforation and/or lead to a higher mortality rate.
Asteroseismology of iota Draconis and Discovery of an Additional Long-period Companion
Authors: Hill Michelle L. , Kane Stephen R. , Campante Tiago L. , Li Zhexing , Dalba Paul A. , Brandt Timothy D. , White Timothy R. , Pope Benjamin J. S. , Stassun Keivan G. , Fulton Benjamin J. , Corsaro Enrico , Li Tanda , Ong J. M. Joel , Bedding Timothy R. , Bossini Diego , Buzasi Derek L. , Chaplin William J. , Cunha Margarida S. , García Rafael A. , Breton Sylvain N. , Hon Marc , Huber Daniel , Jiang Chen , Kayhan Cenk , Kuszlewicz James S. , Mathur Savita , Serenelli Aldo , Stello Dennis 
Published: October 2021

Abstract
Giant stars as known exoplanet hosts are relatively rare due to the potential challenges in acquiring precision radial velocities and the small predicted transit depths. However, these giant host stars are also some of the brightest in the sky and so enable high signal-to-noise ratio follow-up measurements. Here, we report on new observations of the bright (V ∼ 3.3) giant star ι Draconis (ι Dra), known to host a planet in a highly eccentric ∼511 day period orbit. TESS observations of the star over 137 days reveal asteroseismic signatures, allowing us to constrain the stellar radius, mass, and age to ∼2%, ∼6%, and ∼28%, respectively. We present the results of continued radial-velocity monitoring of the star using the Automated Planet Finder over several orbits of the planet. We provide more precise planet parameters of the known planet and, through the combination of our radial-velocity measurements with Hipparcos and Gaia astrometry, we discover an additional long-period companion with an orbital period of

∼

68

−
36

+
60

yr. Mass predictions from our analysis place this substellar companion on the border of the planet and brown dwarf regimes. The bright nature of the star combined with the revised orbital architecture of the system provides an opportunity to study planetary orbital dynamics that evolve as the star moves into the giant phase of its evolution.
Zodiacal Exoplanets in Time (ZEIT). XIV. He i Transit Spectroscopy of the 650 Myr Hyades Planet K2-136c
Authors: Gaidos Eric , Hirano Teruyuki , Omiya Masashi , Kuzuhara Masayuki , Kotani Takayuki , Tamura Motohide , Harakawa Hiroki , Kudo Tomoyuki 
Published: October 2021

Abstract
We report the non-detection of excess absorption in the 1083.2 nm line of neutral triplet helium during a transit of K2-136c, a 2.9R
⊕ planet on a 17.3 days orbit around a K-type dwarf in the 650 Myr old Hyades cluster. We limit the equivalent width of any transit-associated absorption in the He i line to <25 mÅ at 99% confidence.
L’activité clandestine chez les aides-soignants : quelle reprise en formation ?
Authors: Muñoz Gregory , Parage Pierre , Simonet Pascal 
Published: October 2021

Face à la productivité exacerbée (Rosa, 2014) des organisations «paradoxantes » (De Gaulejac, 2011), les conflits cognitifs de buts (Rabardel, 2005 ; Pastré, 2011) chez les aides-soignant(e)s (AS) changent de régime (Parage & Munoz, 2017), passant d’une logique du « et » (care et cure) à une logique du « ou » ; ce qui oblige les professionnels à trancher, portant ainsi atteinte à leur éthique professionnelle, et versant dans le conflit de valeurs (Parage & Munoz, 2013 ; Jaeger, 2009). Par le recours à des instructions au sosie (Clot, 2001 ; Miossec, 2017), pour accéder à une part de leur activité, nos premiers résultats positionnent les AS entre résignation, apparentée parfois à un retrait, et résistance, présentant un engagement collectif ou individuel. Une activité clandestine (Dejours, 2003) leur permet de ne pas subir les situations de conflit et de reprendre la main sur leur travail, y compris parfois envers et contre le collectif. Comment cette analyse questionne-t-elle la formation ? Comment les formateurs d’AS se saisissent-ils de ces formes d’activités clandestines ?