bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Sikap Resiliensi Pada Masa Pandemi Covid-19 Terhadap Kemampuan Akademik Mahasiswa Pada Mata Kuliah Evaluasi Pedidikan
Authors: Situmeang Muhamad sukri 
Published: September 2021

Penelitian ini bertujuan untuk mengetahui hubungan antara sikap resiliensi pada masa pandemic covid-19 dengan kemampuan akademik mahasiswa pada mata kuliah Evaluasi Pembelajaran. Penelitian ini berlatar belakang pada masa pandemi covid-19 dimana perkuliahan ini sepenuhnya dilaksanakan pada masa tersebut. Metode yang digunakan dalam penelitian ini adalah adalah metode survey dengan teknik korelasi. Populasi dalam penelitian ini adalah seluruh mahasiswa program studi Kependidikan Islam STAI Publisistik Thawalib Jakarta. Adapun sampel dalam peneltian ini sebanyak 17 orang mahasiswa yang mengambil mata kuliah Evaluasi Pembelajaran dengan menggunakan teknik purpose sampling sample. Instrumen dalam penelitian ini menggunakan bentuk soal tes uraian kemampuan akademik dan bentuk soal non tes skala sikap resiliensi. Hasil penelitian menunjukkan bahwa terdapat pengaruh yang positif antara sikap resiliensi dengan kemampuan akademik mahasiswa, dengan Pengaruh sikap resiliensi sebesar 59,4 % terhadap kemampuan akademik mahasiswa dan 40,6% karena pengaruh variabel lainnya.

Kata Kunci : Sikap resiliensi, kemampuan akademik, evaluasi pembelajaran.
Dakwah Majelis Ulama Indonesia dan Perubahan Iklim
Authors: Hilabi Abd Hilabi 
Published: September 2021

Perubahan iklim akibat adanya pemanasan global, pemanasan global adalah terjadinya peningkatan temperatur rata-rata atmosfer, laut, dan daratan bumi. Pemanasan global disebabkan adanya efek rumah kaca. Efek rumah kaca sendiri disebabkan karena naiknya konsentrasi gas Karbondioksida (CO2) dan gas-gas lainnya di atmosfer. jika setiap Muslim memiliki kesadaran akan kewajibannya sebagai khalifatullah fil Ard, maka bukanlah perkara yang sulit bagi umat Islam untuk memulai dan mendakwahkan pentingnya menjaga keseimbangan lingkungan ke segenap penjuru dunia, termasuk negara-negara kapitalis-industrialis yang banyak menyumbangkan emisi gas Karbondioksida yang memicu global warming - bersama-sama berkomitmen untuk menjaga keseimbangan lingkungan. Dengan demikian, pemanasan global di muka bumi bisa dihentikan.

Kata Kunci: Dakwah, Perubahan iklim, Pemanasan global
Hubungan Antara Tingkat Keharmonisan Keluarga Dan Kematangan Terhadap Emosional Anak Kelas X Akuntansi Di SMK Tadika Pertiwi Cinere Depok
Authors: Haryantini Yanti 
Published: September 2021

Tujuan penelitian ini dilakukan untuk mengetahuu: 1) Ingin mendapatkan informasi secara objektif tentang hubungan antara tingkat keharmonisan keluarga dan kematangan emosi siswa di SMK Taraka Pertiwi Cinere. dan 2). mengetahu hubungan antara keharmonisan keluarga dan kemampuan emosi siswa.
Sampel diambil secara random sampling sebanyak 80 siswa, diambil dari tiap-tiap kelas 10 siswa. variabel yang diteliti ada 2 yaitu keharmonisan keluarga sebagai variabel bebas dan kematangan emosi siswa sebagai variabel terikat data diambil dengan angket dan skala psikologi. data yang diperoleh dianalisis menggunakan analisis korelasi product momen.
Hasil analisis deskriptif presentase menunjukkan bahwa keharmonisan keluarga siswa-siswa di SMK Taraka Pertiwi Cinere adalah dalam kriteria sedang yaitu dengan persentase 67,34% sedangkan kematangan emosi siswa termasuk kriteria sedang yaitu dengan persentase 67,96%, hasil analisis korelasi memperoleh koefisien korelasi 0,459. Pada a = 5% dengan N = 80 diperoleh ttabel = 0,220 karena rhitung = 0,459 > rtabel = 0,220 yang berarti ada hubungan antara keharmonisan keluarga dan kematangan emosi siswa di SMK Taraka Pertiwa Cinere.

Kata Kunci: Keharmonisan keluarga, Kematangan emosional siswa
Media Interaktif Adobe Flash CS6 dengan Model Dart dalam Pembelajaran Bahasa Arab Di Era Pandemi Covid-19
Authors: Irsyad Muhammad 
Published: September 2021

Di zaman modern sekarang ini terdapat macam-macam cara dalam pembelajaran, salah satunya adalah pembelajaran melalui Adobe Flash CS6. Pembelajaran bahasa Arab dapat dilakukan dengan menggunakan media interaktif Adobe Flash CS6, terlebih pada masa pandemi virus covid 19 seperti sekarang ini. Jenis penelitian ini merupakan penelitian library research, dan peneliti memperoleh data dalam penelitian ini berupa sumber data primer yang diperoleh dari buku yang ditulis oleh Ichwan K yang berjudul Membuat Media Pembelajaran dengan Adobe Flash CS6 yang diterbitkan pada tahun 2015 oleh CV Andi Offset, buku yang ditulis oleh Deni Darmawan yang berjudul Inovasi Pendidikan yang diterbitkan pada tahun 2012 oleh PT Remaja Rosdakarya, dan Jurnal yang ditulis oleh Poppy Kamalia Devi yang berjudul DART dalam pembelajaran IPA. Dan data sekunder dalam penelitian ini peneliti memperoleh dari membaca buku-buku, artikel-artikel, dan literatur yang berbentuk cetak maupun elektronik, serta studi-studi terdahulu yang berkaitan dengan tujuan dan objek penelitian. Penelitian ini bertujuan membantu pendidik agar dapat membuat media pembelajaran menggunakan adobe flash CS 6 sehingga memudahkan pendidik dan peserta didik dalam melaksanakan proses belajar dengan lebih mendalam. Hal ini disebabkan karena media interaktif adobe flash CS 6terdapat komunikasi dua arah antara peserta didik dan media, mempunyai feedback (timbal balik) langsung, terdapat input data, meliputi aktivitas fisik dan mental, terdapat mouse klik atau mouse enter sehingga peserta didik dapat belajar secara aktif dan mandiri saat menggunakan media interaktif ini.
Kata Kunci: Media Interaktif, Adobe Flash CS6, DART (Directed Activities Rolated to Texts)
Pengaruh Sikap Spiritual Terhadap Kepercayaan Diri Mahasiswa Peserta Sidang Munaqasyah Pada Masa Pandemi Covid-19
Authors: Situmeang Sukri 
Published: September 2021

Penelitian ini bertujuan untuk mengetahui pengaruh antara sikap spiritual pada masa pandemic covid-19 terhadap kepercayaan diri mahasiswa peserta sidang munaqasyah. Penelitian ini berlatar belakang pada masa pandemi covid-19 dimana sidang munaqasyah ini sepenuhnya dilaksanakan secara terbatas dengan menerapkan protokol kesehatan yang ketat. Metode yang digunakan dalam penelitian ini adalah adalah metode survey dengan teknik korelasi. Populasi dalam penelitian ini adalah seluruh mahasiswa program studi pendidikan guru MI STAI Publisistik Thawalib Jakarta. Adapun sampel dalam peneltian ini sebanyak 20 orang mahasiswa yang mengikuti sidang munaqasyah dengan menggunakan teknik purpose sampling sample. Instrumen dalam penelitian ini menggunakan bentuk soal non tes skala sikap spiritual dan kepercayaan diri mahasiswa. Hasil penelitian menunjukkan bahwa terdapat pengaruh yang positif antara sikap spiritual terhadap kepercayaan diri mahasiswa peserta sidang munaqasyah, dengan Pengaruh sikap spiritual sebesar 57,9 % terhadap kepercayaan diri mahasiswa dan 42,1% karena pengaruh variabel lainnya.
Kata Kunci: Sikap spiritual, kepercayaan diri, sidang munaqasyah.
Adam21 is dispensable for reproductive processes in mice
Authors: Chen Yinghong , Liu Chao , Shang Yongliang , Wang Liying , Li Wei , Li Guoping 
Published: September 2021

Background
As a group of membrane-anchored proteins, the proteins containing a disintegrin and metalloprotease domain (ADAMs) control many biological processes, especially for male fertility. Mouse Adam21 was previously found to be specifically expressed in the somatic cells and germ cells of testes, but its functional role during spermatogenesis and male reproductive processes is still unknown.

Methods
Adam21-null mice were created using the CRISPR/Cas9 system. Quantitative real-time PCR was used for analyzing of gene expression. Histological, cytological and immunofluorescence staining were performed to analyze the phenotypes of mouse testis and epididymis. Intracellular lipid droplets (LDs) were detected by Oil red O (ORO) staining and BODIPY staining. Fertility and sperm characteristics were also detected.

Results
Here, we successfully generated an Adam21 conventional knockout mouse model via CRISPR/Cas9 technology so that we can explore its potential role in male reproduction. We found that male mice lacking Adam21 have normal fertility without any detectable defects in spermatogenesis or sperm motility. Histological analysis of the seminiferous epithelium showed no obvious spermatogenesis difference between Adam21-null and wild-type mice. Cytological analysis revealed no detectable defects in meiotic progression, neither Sertoli cells nor Leydig cells displayed any defect compared with that of the control mice. All these results suggest that Adam21 might not be essential for male fertility in mice, and its potential function still needs further investigation.
The Annual Diagnostic Prevalence of Ankylosing Spondylitis and Axial Spondyloarthritis in the United States Using Medicare and MarketScan Databases
Authors: Curtis Jeffrey R. , Winthrop Kevin , Bohn Rhonda L. , Suruki Robert , Siegel Sarah , Stark Jeffrey L. , Xie Fenglong , Yun Huifeng , Chen Lang , Deodhar Atul 
Published: September 2021

ObjectiveThe objective of this study was to investigate the diagnostic prevalence of ankylosing spondylitis (AS) and axial spondyloarthritis (axSpA) in the United States and examine treatment patterns for these diseases.MethodsThis retrospective observational cohort study drew from 2006‐2014 data in the US Medicare Fee‐for‐Service and IBM MarketScan databases. AS and axSpA diagnoses were identified through International Classification of Diseases, Ninth Revision [ICD‐9] codes. Diagnostic prevalence (per 10,000 patients) was calculated as patients with AS and axSpA with full insurance coverage in each calendar year divided by the total patients with full insurance coverage in the same year. Two diagnosis definitions were used: definition 1 (D1), one or more relevant ICD‐9 codes from hospital claims or two or more relevant ICD‐9 codes from outpatient claims; definition 2 (D2), one or more codes from hospital/outpatient claims. Primary analyses assessed annual AS and axSpA prevalence (D1); sensitivity analyses assessed annual (D2) and 2‐year prevalence. Patterns in prevalence and treatment use were analyzed descriptively; no statistical tests were performed.ResultsAn increase in AS prevalence (per 10,000 patients) was seen from 2006 to 2014 in primary analyses (Medicare: 2.12‐3.60; MarketScan: 0.85‐1.42) and sensitivity analyses. A similar trend occurred for axSpA (Medicare: 4.39‐6.52; MarketScan: 1.33‐2.21). For Medicare, the proportion of patients with AS (D1) using tumor necrosis factor α inhibitors (TNFis), conventional synthetic antirheumatic drugs (csARDs), nonsteroidal antiinflammatory drugs (NSAIDs), opioids, and glucocorticoids remained relatively stable; for MarketScan, TNFi‐treated patients increased (51.7% to 65.7%) and NSAID‐treated patients decreased (63.5% to 55.7%).ConclusionAS and axSpA prevalence may have increased in the United States between 2006 and 2014. Reasons are unknown, but this may be due to increased disease awareness, among other factors.
Mechanical Stress Induces a Transient Suppression of Cytokine Secretion in Astrocytes Assessed at the Single‐Cell Level with a High‐Throughput Microfluidic Chip
Authors: Shao Xiaowei , Wang Chunhua , Wang Chao , Han Lei , Han Yunrui , Nižetić Dean , Zhang Yu , Han Lin 
Published: September 2021

AbstractBrain cells are constantly subjected to mechanical signals. Astrocytes are the most abundant glial cells of the central nervous system (CNS), which display immunoreactivity and have been suggested as an emerging disease focus in the recent years. However, how mechanical signals regulate astrocyte immunoreactivity, and the cytokine release in particular, remains to be fully characterized. Here, human neural stem cells are used to induce astrocytes, from which the release of 15 types of cytokines are screened, and nine of them are detected using a protein microfluidic chip. When a gentle compressive force is applied, altered cell morphology and reinforced cytoskeleton are observed. The force induces a transient suppression of cytokine secretions including IL‐6, MCP‐1, and IL‐8 in the early astrocytes. Further, using a multiplexed single‐cell culture and protein detection microfluidic chip, the mechanical effects at a single‐cell level are analyzed, which validates a concerted downregulation by force on IL‐6 and MCP‐1 secretions in the cells releasing both factors. This work demonstrates an original attempt of employing the protein detection microfluidic chips in the assessment of mechanical regulation on the brain cells at a single‐cell resolution, offering novel approach and unique insights for the understanding of the CNS immune regulation.
A Liquid Metal Mediated Metallic Coating for Antimicrobial and Antiviral Fabrics
Authors: Kwon Ki Yoon , Cheeseman Samuel , Frias‐De‐Diego Alba , Hong Haeleen , Yang Jiayi , Jung Woojin , Yin Hong , Murdoch Billy J. , Scholle Frank , Crook Nathan , Crisci Elisa , Dickey Michael D. , Truong Vi Khanh , Kim Tae‐il 
Published: September 2021

AbstractFabrics are widely used in hospitals and many other settings for bedding, clothing, and face masks; however, microbial pathogens can survive on surfaces for a long time, leading to microbial transmission. Coatings of metallic particles on fabrics have been widely used to eradicate pathogens. However, current metal particle coating technologies encounter numerous issues such as nonuniformity, processing complexity, and poor adhesion. To overcome these issues, an easy‐to‐control and straightforward method is reported to coat a wide range of fabrics by using gallium liquid metal (LM) particles to facilitate the deposition of liquid metal copper alloy (LMCu) particles. Gallium particles coated on the fabric provide nucleation sites for forming LMCu particles at room temperature via galvanic replacement of Cu2+ ions. The LM helps promote strong adhesion of the particles to the fabric. The presence of the LMCu particles can eradicate over 99% of pathogens (including bacteria, fungi, and viruses) within 5 min, which is significantly more effective than control samples coated with only Cu. The coating remains effective over multiple usages and against contaminated droplets and aerosols, such as those encountered in facemasks. This facile coating method is promising for generating robust antibacterial, antifungal, and antiviral fabrics and surfaces.
Photoswitchable Configuration of Nematic Liquid Crystal Droplets Embedded in a Honeycomb‐Patterned Film
Authors: Mukai Koji , Hara Mitsuo , Yabu Hiroshi , Nagano Shusaku , Seki Takahiro 
Published: September 2021

AbstractHoneycomb‐patterned polymer films prepared by the breath figure method exhibit unique shape features. These films have potential in various applications, but functional materials are rarely embedded into the arrayed cavity. Here, a photoswitchable function of a compartmented nematic liquid crystal (NLC) in a honeycomb array is proposed. Surface segregation and liquid crystal self‐assembly processes cover curved honeycomb walls of polystyrene (PS) with a high‐density polymer brush of an azobenzene side chain liquid crystalline polymer (SCLCP), producing honeycomb polymer films with isolated cavities. Spherical confinement of the cavities with the SCLC brush provides a bipolar nematic director (planar anchoring), whereas UV light irradiation induces a radial configuration (homeotropic anchoring) of NLC droplets. Photoisomerization of azobenzene UV and visible light irradiation repeatedly induces a photoswitchable change between the bipolar and radial modes.
Integrated Bifunctional Oxygen Electrodes for Flexible Zinc–Air Batteries: From Electrode Designing to Wearable Energy Storage
Authors: Yang Xuhuan , Li Simeng , Ye Dewei , Kuang Jiaqi , Guo Shu , Zou Yueyuan , Cai Xin 
Published: September 2021

AbstractThe strong propulsion stem from flexible/wearable electronics has greatly stimulated the development of miniaturized and high‐performance rechargeable batteries with adaptable shape. Flexible zinc–air batteries (FZABs), which exhibit high theoretical energy density (1218 Wh kg−1), low cost, environmental benignancy, and admirable operational safety, have been widely recognized as one of the promising portable powers to serve future wearable electronics for ubiquitous application. During the past five years, the energy/power density and cycling stability of FZABs have gained significant improvement largely due to the rational construction of high‐efficiency bifunctional air electrodes. Herein, the recent progress of integrated binder‐free bifunctional oxygen electrodes is overviewed via elaborate in situ preparation and interface engineering for FZABs. In particular, fiber/cable‐type ZABs with unrivaled omnidirectional‐flexibility and unique knittability are highlighted in virtue of their enormous potential to realize wearable batteries and smart fabrics. From a practical point of view, the recently proposed rechargeable ZABs for integrated/hybridized devices or self‐powered energy systems are reviewed. Finally, the remained challenges and some insightful directions for the future development of high‐performance FZABs are illustrated in the pursuit of cost‐efficient portable powers and multifunctional flexible/wearable electronic devices.
A Self‐Powered Early Warning Glove with Integrated Elastic‐Arched Triboelectric Nanogenerator and Flexible Printed Circuit for Real‐Time Safety Protection
Authors: Zu Lulu , Liu Di , Shao Jiajia , Liu Yuan , Shu Sheng , Li Chengyu , Shi Xue , Chen Baodong , Wang Zhong Lin 
Published: September 2021

AbstractA matched and self‐powered supply for a variety of wearable electronics remains a critical challenge. Here, a fully self‐powered early warning glove (SEWG) is developed via unique elastic‐arched triboelectric nanogenerator (EA‐TENG) and flexible printed circuit technology. The EA‐TENG generates electricity from a continuous touch lightly by hand or body, as a sustainable self‐powered source that can be utilized to complete one charging process by simply five times slapping. The SEWG has the advantage that can really deliver real‐time no‐contact electrostatic monitoring when no external power is supplied, and can effectively avoid the electric shock accident in 220/380 V electric maintenance work. Quantitative analysis of the mechanical and electronic characteristics of the SEWG demonstrated its advantages in terms of stability and reliability, with consistently well performance over more than 80,000 working cycles. It is anticipated that the special design of integrated self‐powered system could produce more implications in the field of wearable/flexible electronics and human‐machine interaction.
Lewis Acid Regulated Divergent Catalytic Reaction between Quinone Imine Ketals (QIKs) and 1,3‐Dicarbonyl Compounds: Switchable Access to Multiple Products Including 2‐Aryl‐1,3‐Dicarbonyl Compounds, Indoles, and Benzofurans
Authors: Chen Xingyu , Lu Sixian , Deng Ping , Chang Xiaoqiang , Zhao Yifan , Ma Yue , Zhang Dong , Xia Fei , Yang Lan , Wang Jigang , Sun Peng 
Published: September 2021

AbstractA catalytic Lewis acid regulated reaction between quinone imine ketals (QIKs) and 1,3‐dicarbonyl compounds provides a divergent and tunable approach to a variety of skeletons, including a series of 2‐aryl‐1,3‐dicarbonyl compounds, indoles, and benzofurans. The use of lithium chloride and ferrous bromide gives C3‐ or C2‐alkylation products of the QIKs. The combination of ferrous bromide and trifluoromethanesulfonic acid delivers indole derivatives. Sequential hydrolysis and C3‐alkylation occur in the presence of ytterbium (III) trifluoromethanesulfonate and stoichiometric amounts of water. When the reaction is performed with trifluoromethanesulfonic acid and stoichiometric amounts of water, benzofuran is obtained. This protocol utilizes mild conditions, exhibits regio‐ and chemoselectivity, and has broad functional group tolerance.magnified image
Using Stereochemistry to Control Mechanical Properties in Thiol–Yne Click‐Hydrogels
Authors: Macdougall Laura J. , Pérez‐Madrigal Maria M. , Shaw Joshua E. , Worch Joshua C. , Sammon Christopher , Richardson Stephen M. , Dove Andrew P. 
Published: September 2021

AbstractThe stereochemistry of polymers has a profound impact on their mechanical properties. While this has been observed in thermoplastics, studies on how stereochemistry affects the bulk properties of swollen networks, such as hydrogels, are limited. Typically, changing the stiffness of a hydrogel is achieved at the cost of changing another parameter, that in turn affects the physical properties of the material and ultimately influences the cellular response. Herein, we report that by manipulating the stereochemistry of a double bond, formed in situ during gelation, materials with diverse mechanical properties but comparable physical properties can be obtained. Click‐hydrogels that possess a high % trans content are stiffer than their high % cis analogues by almost a factor of 3. Human mesenchymal stem cells acted as a substrate stiffness cell reporter demonstrating the potential of these platforms to study mechanotransduction without the influence of other external factors.
APEX2‐based Proximity Labeling of Atox1 Identifies CRIP2 as a Nuclear Copper‐binding Protein that Regulates Autophagy Activation
Authors: Chen Lin , Li Na , Zhang Meiqi , Sun Mingming , Bian Jiaxuan , Yang Bo , Li Zhengcunxiao , Wang Jiayu , Li Fei , Shi Xiaomeng , Wang Yuan , Yuan Feng , Zou Peng , Shan Changliang , Wang Jing 
Published: September 2021

AbstractMammalian cell nuclei contain copper, and cancer cells are known to accumulate aberrantly high copper levels, yet the mechanisms underlying nuclear accumulation and copper's broader functional significance remain poorly understood. Here, by combining APEX2‐based proximity labeling focused on the copper chaperone Atox1 with mass spectrometry we identified a previously unrecognized nuclear copper binding protein, Cysteine‐rich protein 2 (CRIP2), that interacts with Atox1 in the nucleus. We show that Atox1 transfers copper to CRIP2, which induces a change in CRIP2′s secondary structure that ultimately promotes its ubiquitin‐mediated proteasomal degradation. Finally, we demonstrate that depletion of CRIP2‐as well as copper‐induced CRIP2 degradation‐elevates ROS levels and activates autophagy in H1299 cells. Thus, our study establishes that CRIP2 as an autophagic suppressor protein and implicates CRIP2‐mediated copper metabolism in the activation of autophagy in cancer cells.
Ultrathin Crystalline Covalent‐Triazine‐Framework Nanosheets with Electron Donor Groups for Synergistically Enhanced Photocatalytic Water Splitting
Authors: Wang Congxu , Zhang Hualei , Luo Wenjia , Sun Tian , Xu Yuxi 
Published: September 2021

AbstractUltrathin nanosheets have great potential for photocatalytic applications, however, suffer from enlarged band gap and narrowed visible‐light‐responsive range due to the quantum confinement effect. Herein, we report a novel redox strategy for efficient preparation of ultrathin crystalline amide‐functionalized covalent‐triazine‐framework nanosheets (CTF NSs) with enhanced visible light absorption. The CTF NSs exhibited photocatalytic hydrogen (512.3 μmol h−1) and oxygen (12.37 μmol h−1) evolution rates much higher than that of pristine bulk CTF. Photocatalytic overall water splitting could be achieved with efficient stoichiometric H2 (5.13 μmol h−1) and O2 (2.53 μmol h−1) evolution rates under visible light irradiation. Experimental and theoretical analysis revealed that introduction of amide groups as electron donor optimized the band structure and improve its visible‐light absorption, hydrophilicity and carrier separation efficiency, thus resulting in the enhanced photocatalytic performance. The well‐dispersed CTF NSs could be easily cast onto a support as a thin film device and demonstrate excellent photocatalytic activity (25.7 mmol h−1 m−2 for hydrogen evolution).