bluuebunny/crossref_metadata_2025_split huggingface dataset:
Béla Bartók
Authors: Hooker Lynn , Laki Peter , Witt Alexis 
Published: March 2021

Béla Bartók (b. 1881–d. 1945) was one of the most influential musical figures of the 20th century, particularly from outside the historic musical centers of Germany, France, and Italy. Now remembered principally as a composer, he was also an international concert pianist, teacher of piano, and pioneer in folk music research. Bartók was born and educated in the provincial periphery of late-19th-century Hungary; when he was admitted to institutions in both Vienna and Budapest for his advanced education, he made the fateful decision to enroll in Budapest’s Royal Academy of Music. In 1907 he joined its piano faculty, continuing until 1934, when he transferred to a full-time position doing folk music research at the Hungarian Academy of Sciences. He performed his works widely, especially during the interwar period, though after 1934 his performances in Germany ceased, in part due to his refusal to certify his Aryan origins. As Bartók grew uneasy about Hungary’s alliance with the Third Reich, he and his wife left after his mother’s death, landing in New York in 1940. He died there of leukemia in 1945. After modeling his early works on the chromaticism of Richard Strauss combined with 19th-century Hungarian-style motifs, Bartók changed his musical direction after his discovery of the folk songs of isolated peasantry, first by chance in 1904 and then in systematic fieldwork with Zoltán Kodály beginning in 1905. Bartók studied village music of not only Hungarians but also other ethnic groups around East-Central Europe, North Africa, and Turkey. His study of these materials along with the music of earlier composers, particularly Debussy, Liszt, and Beethoven, were his sources for new modes of organization of pitch, rhythm, and form. He also responded in music and words to other modernist musicians of his time; several scholars have investigated the issue of who influenced whom. At the height of his career, he departed radically from tonality and reinterpreted classical forms in some works, while at the same time writing a variety of more accessible and frequently performed character pieces, folk song settings, and pedagogical works. Some of the large-scale works he produced at the end of his life, most notably the Concerto for Orchestra (1943), combined ambition of scale and accessibility in a way that made for great success with the public. However, some postwar modernist critics, who debated the issue of accessibility through a Cold War lens, saw Bartók’s popularity as a sign of selling out to audiences rather than following the “mandate of history.” Bartók scholars have addressed a wide range of topics, from cultural studies of his interactions with other artists in Hungary and abroad, to his folk music research, to close readings of his compositions from biographical, literary, or source-studies perspectives, to a multitude of music-theoretical analyses. This bibliography provides a representative survey of the voluminous Bartók scholarship.
Occupational health management of work-related stress: guidelines versus practice
Authors: Palka G , Sen D 
Published: March 2021

Abstract

Background
Work-related stress, anxiety and depression (WRSAD) are common, overlapping mental health problems burdened with major medical, occupational, institutional and societal implications. Current occupational health (OH) management of WRSAD is based on clinical and managerial guidelines and individual risk assessment.

Aims
The study sought to identify patterns of OH advice in WRSAD and the relationships between the OH advice, available evidence, experience and expertise of the OH doctors (OHDs).

Methods
A retrospective cross-sectional analysis of 101 first-time OH consultations for WRSAD by nine OHDs.

Results
The three most common OH interventions included follow-up OH consultations, adjusted duties and referrals for counselling. All OHDs preferred a light-touch approach but the less experienced and qualified OHDs were more proactive and prescriptive.

Conclusions
In the absence of a specific occupational medical guideline for the management of WRSAD, the OH interventions may be guided by clinical guidelines, individual risk assessment, the client’s circumstances or the experience, expertise and preferences of the OHDs. In the study group, OH interventions were under-utilized and not consistently applied. Our findings support the argument for OH guideline for WRSAD to improve the consistency and effectiveness of OH interventions. This is important given the scale of the problem and the recent increase in WRSAD during the COVID-19 pandemic.
Cynotherapy in Cancer Pain Management: A Pilot Study
Authors: Silva Carvalho Filipe , Carvalho Susana , Conde Rita , Esteves Susana 
Published: March 2021

Abstract

Objectives
This was a pilot study to evaluate the feasibility and impact of a single dog-assisted therapy (cynotherapy) session in reducing pain and emotional distress in oncological outpatients compared with typical waiting room experience (control).

Design
This was a quasi-experimental before-after controlled study that took place at a chronic pain outpatient clinic of a tertiary cancer center, whose participants were adult oncological patients, able to consent and without medical contraindication.

Setting
Chronic pain outpatient clinic of a tertiary cancer center.

Participants
Adult oncological patients able to consent and without medical contraindication.

Methods
All participants completed self-reported questionnaires including a numeric rating scale for pain and distress thermometer at admission and immediately before departure from the clinic.

Results
Eighty-one patients were enrolled over a 10-month study period, 41 in the cynotherapy group and 40 controls. Improvement was greater in cynotherapy than control group for pain (median difference score = -1.0 vs 0.0; P = 0.037), distress levels (median = -1.0 vs 0.0; P = 0.017), and depression (median = -1.0 vs 0.0; P = 0.030). The proportion of patients with a clinically relevant improvement in pain (reduction ≥2 points) was approximately twofold in the cynotherapy group when compared with controls, although not statistically significant (39% vs 20%, odds ratio = 2.53, 95% confidence interval = 0.86–8.02; P = 0.088). The mean satisfaction rate was 9.3/10, and no negative occurrences were reported.

Conclusion
A single session of dog-assisted therapy can provide immediate improvement in the perception of pain and distress for patients with chronic cancer pain in an outpatient setting, with high satisfaction rates and no negative occurrences. This nonrandomized pilot study points toward the clinical relevance of implementing cynotherapy at a cancer pain clinic and developing a larger scale, more directed study.
Combining Stress Management With Pain Neuroscience Education and Exercise Therapy in People With Whiplash-Associated Disorders: A Clinical Perspective
Authors: Willaert Ward , Leysen Laurence , Lenoir Dorine , Meeus Mira , Cagnie Barbara , Nijs Jo , Sterling Michele , Coppieters Iris 
Published: March 2021

Abstract
Individuals classified as having whiplash-associated disorder (WAD) grade II, which reflects approximately 93% of people with WAD who are commonly managed by health care professionals, exhibit both physical (eg, pain and disability) and psychological (eg, fear of movement, anxiety, posttraumatic stress) problems that, in approximately 50% of cases, persist beyond 3 months. There is still much ongoing debate regarding factors predictive of poor recovery. The strongest associations have been found for high initial pain and disability following whiplash injury. In addition, a growing body of evidence supports the clinical importance of characteristic features, such as disturbed nociceptive processing (eg, local or general hyperalgesia to cold and mechanical stimuli), inefficient cognitions and beliefs about pain/movement/recovery, and posttraumatic stress symptoms, in the development and maintenance of physical and psychological manifestations in individuals with WAD. For this reason, the field shifted away from single interventions that mainly follow a biomedical approach, such as exercise therapy and activity programs, to gold standard multimodal care (at least 2 distinct therapeutic modalities given by 1 or more health care professionals) that acknowledges the biopsychological nature of WAD. To date, there exist several multimodal care approaches to managing WAD; however, for most, the efficacy has been found to be rather limited. One may argue that the limited success of some approaches can be attributed to the fact that they focused mainly on rehabilitating the physical symptoms (eg, pain, disability) rather than also the associated cognitive (eg, catastrophizing) and psychological (eg, posttraumatic stress symptoms) symptoms of the condition, leaving much room for improvement. In this article, current and previous evidence is used to explain why and how a comprehensive and multimodal treatment for people with WAD—consisting of a combination of pain neuroscience education, cognition-targeted exercise therapy, and stress management—can be applied in clinical practice.
COVID-19 pandemic: health impact of staying at home, social distancing and ‘lockdown’ measures—a systematic review of systematic reviews
Authors: Chiesa Valentina , Antony Gabriele , Wismar Matthias , Rechel Bernd 
Published: March 2021

AbstractBackgroundTo systematically review the evidence published in systematic reviews (SR) on the health impact of staying at home, social distancing and lockdown measures. We followed a systematic review approach, in line with PRISMA guidelines.MethodsIn October 2020, we searched the databases Cochrane Database of Systematic Reviews, Ovid Medline, Ovid Embase and Web of Science, using a pre-defined search strategy.ResultsThe literature search yielded an initial list of 2172 records. After screening of titles and abstracts, followed by full-text screening, 51 articles were retained and included in the analysis. All of them referred to the first wave of the coronavirus disease 2019 pandemic. The direct health impact that was covered in the greatest number (25) of SR related to mental health, followed by 13 SR on healthcare delivery and 12 on infection control. The predominant areas of indirect health impacts covered by the included studies relate to the economic and social impacts. Only three articles mentioned the negative impact on education.ConclusionsThe focus of SR so far has been uneven, with mental health receiving the most attention. The impact of measures to contain the spread of the virus can be direct and indirect, having both intended and unintended consequences.Highlights
The systemic approach as an instrument to evaluate higher education systems: Opportunities and challenges
Authors: Aparicio Juan , Rodríguez Dorys Yaneth , Zabala-Iturriagagoitia Jon Mikel 
Published: March 2021

Abstract
This article aims to provide a systemic instrument to evaluate the functioning of higher education systems. Despite systemic instruments have had a strong impact on the management of public policy systems in fields such as health and innovation, higher education has not been widely discussed in applying this type of instrument. Herein lies the main gap that we want to close. The ultimate purpose of the evaluation instrument introduced here is thus to provide information for decision-makers, so these can identify the strengths/weaknesses in the functioning of their respective higher education systems from a systemic perspective. To achieve the previous goal, we apply the methodological guidelines of the integrative review of the literature. An integrative review of the literature was chosen because it guides the extraction of quantitative evidence from the literature and its classification, with the purpose of integrating the results into an analytical framework. This resulting analytical framework is what we have labelled as the systemic evaluation instrument. The article makes three contributions to the literature. First, the different types of higher education institutions considered in the literature and the higher education systems analysis scales are evidenced. Second, we identify the capacities and functions examined by the literature so that higher education institutions and higher education systems can fulfil their missions. Third, a systemic evaluation framework for higher education institutions and higher education systems is presented. The article concludes with a discussion of the opportunities and challenges associated to the implementation of such a systemic framework for policymaking.
A Quality Improvement Project to Reduce Events of Visitor Escalation in the Intensive Care Nursery
Authors: Schwoebel Ann , Quigley Elizabeth , Deeley Annemarie , DeLuca Joanne , Hollister Stephanie , Ruggiero Joanne 
Published: March 2021

Background:
Escalating and aggressive visitor behaviors have become increasingly common in healthcare settings nationally, negatively impacting staff and patients alike. Most healthcare providers do not innately possess the specific skills to manage such behaviors. Management of escalating and aggressive behaviors presents a particularly bedeviling challenge when staff safety must be balanced with the needs of parent–neonate bonding.

Purpose:
In the Intensive Care Nursery (ICN), the frequency of aggressive and hostile incidents from visitors increased such that the staff felt frustrated by and uneasy about their work environment.

Methods:
The ICN convened an interprofessional team to strategize interventions aimed at consistently managing aggressive behavior and supporting the staff after aggressive and/or hostile visitor encounters.

Findings:
Following staff education and training, the unit launched a de-escalation management algorithm in July 2018 that assisted in identifying high-risk families at admission and drove consistent action and management of all visitor behaviors. In the 12 months following the intervention, the frequency of behavioral escalation decreased by 75% and staff perception of safety increased by 25%.

Implications for Practice:
Collaborating with staff to design consistent strategies to manage aggressive and escalating visitor behavior can improve safety and improve employee satisfaction in the ICN.

Implications for Research:
Additional research on the effectiveness of the algorithm in other ICNs and alternative areas of practice is needed. Furthermore, validation of a staff perception survey measuring the impact of escalating visitor behaviors on employees would be an important next step in this research.

Video abstract available at
https://journals.lww.com/advancesinneonatalcare/Pages/videogallery.aspx?autoPlay=false&videoId=43
Sinonasal cancers treatments: state of the art
Authors: Ferrari Marco , Orlandi Ester , Bossi Paolo 
Published: March 2021

Purpose of review
The present review provides the reader with the state-of-the-art concepts of sinonasal oncology in view of the latest literature data.

Recent findings
Most recent publications in sinonasal oncology assessed treatment timing, centralization, surgical approach, margin status, orbit/neck management, salvage strategies, emerging surgical technologies, intensity-modulated radiation therapy (IMRT), volumetric modulated arc therapy (VMAT), particle radiotherapy, and neoadjuvant chemotherapy.

Summary
Indications to endoscopic surgery for sinonasal cancer have plateaued and are unlikely to further expand. Endoscopic surgery provides noninferior results compared to open surgery and best suits timing constraints imposed by multimodal treatment. Management of orbit-encroaching sinonasal cancer is remarkably improving mostly owing to optimal use of nonsurgical strategies. Prognostic value of the margin status and management of the nodal basin and recurrent sinonasal tumors are far from being fully elucidated. Most promising surgical technologies are surgical navigation, optical imaging, and radiofrequency-aided ablation. IMRT and VMAT have theoretical technical advantages that are in the process of being clinically demonstrated. Pieces of evidence are progressively confirming the physical and radiobiological advantages offered by particle radiotherapy. Systemic therapy is being tested mostly in the neoadjuvant setting with the aim of improving outcomes in locally advanced sinonasal cancers; response to induction chemotherapy could better select a further locoregional approach.
Integrated Chinese and western medicine for SLE
Authors: Cheng Xueli , Liu Jing , Zhong Zhenghong , Xu Donghan , Cha Xushan , Wu Qibiao 
Published: March 2021

Abstract

Background:
The efficacy and safety of integrated Chinese and western medicine in the treatment of Systemic Lupus Erythematosus (SLE) have not been systematically evaluated.

Methods:
This systematic review and meta-analysis will be performed and reported according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. We will search PubMed, Embase, Cochrane Library, Chinese Biomedical Database WangFang, VIP, and China National Knowledge Infrastructure (CNKI) for potentially eligible studies from their inception to Dec. 2020, and we will select all the eligible randomized controlled trials (RCTs) of the integrated Chinese and western medicine for Systemic Lupus Erythematosus. All the studies will be screened according to the inclusion and exclusion criteria and meta-analysis will be conducted using Review Manager V.5.3. and Stata V.12.0. The primary endpoint was the clinical efficacy rate, the secondary outcomes were SLEDAI score, adverse reaction rate, and laboratory test parameters (white blood cells, complement C3).

Results:
The results of this study will systematically evaluate the effectiveness and safety of the integrated Chinese and western medicine in the treatment of primary dysmenorrhea.

Conclusion:
The efficacy and safety of integrated Chinese and western medicine will be systematically evaluated in this paper, thus providing evidence for the clinical application of this therapy.

Ethics and dissemination:
This study is a systematic review, which is based on the published studies, so examination and agreement by the ethics committee are not required in this study. We intend to publish the study results in a journal or conference presentations.

Open Science Framework (OSF)registration number:

https://osf.io/mabxh.
Effect of Baduanjin exercise on cervical spondylosis
Authors: Zou Liang , Zhong Chongfu , Xu Xiaohui , Liu Fanjie , Wang Congan , Shi Bin 
Published: March 2021

AbstractBackground:The study aims to evaluate the effectiveness and safety of Baduanjin exercise for patients with cervical spondylosis (CS).Methods:We will retrieve a randomized controlled trial of Baduanjin for CS from the following electronic databases establishment to May 2021: The Cochrane Library, MEDLINE, EMBASE, Web of Science, Springer, World Health Organization International Clinical Trials Registry Platform (ICTRP), China National Knowledge Infrastructure (CNKI), Wan-fang database, Chinese Scientific Journal Database (VIP), Chinese Biomedical Literature Databases (CBM), and other databases. Two independent researchers will operate article retrieval, duplication removing, screening, quality evaluation, and data analyses by Review Manager (V.5.3.5). Meta-analyses, subgroup analysis, and/or descriptive analysis will be performed based on the included data conditions.Results:The results of this study will provide researchers in the field of CS with a current synthesis of high-quality evidence.Conclusion:This conclusion of this study will provide the evidence of whether Baduanjin is an effective and safe intervention for patients with CS.PROSPERO registration number:CRD42020211019.
Celiac Disease Management in the United Kingdom Specialist Pediatric Gastroenterology Centers—A Service Survey
Authors: Paul Siba Prosad , Balakumar Varathagini , Gillett Peter Michael 
Published: March 2021

ABSTRACTObjectives:The 2012 European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN) guidelines on celiac disease (CD) recommended a no‐biopsy pathway (NBP) for symptomatic children with high immunoglobin A (IgA)‐based anti‐tissue transglutaminase (TGA‐IgA) titers, positive anti‐endomysial antibody and human leukocyte antigen (HLA)‐DQ2/DQ8 status. We aimed to understand variations in practice amongst specialist pediatric gastroenterology centers (SPGIC) in the United Kingdom (UK).Methods:A survey questionnaire was sent to all UK SPGIC (n = 29) providing endoscopy services for CD diagnosis. It was divided into four main subgroups: analyzing diagnosis of CD through adherence to the ESPGHAN (2012) guidelines, post‐diagnosis care and long‐term follow‐up and discharge from pediatric services.Results:All 29 responded. NBP was implemented in 28 of 29 centers. Five of 29 centers had already stopped HLA‐DQ2/DQ8 testing for NBP diagnosis. Twenty six of 29 centers were performing endoscopy on screening‐identified children (mostly asymptomatic, “at‐risk” patients). Diagnosis was communicated by a doctor in 65% SPGIC (n = 19). Most centers (n = 23) waited 6–12 months post‐diagnosis to start gluten‐free oats. Routine vitamin D supplementation was commenced by 4 of 29 centers. All centers repeated TGA‐IgA to assess normalization but at varying times post‐GFD. Follow‐up was with a combination of doctors/dieticians (n = 26). Eleven of 29 centers discharged their patient to primary care.Conclusions:There was excellent uptake of ESPGHAN guidelines (2012) in the UK and adherence to guidelines is generally good. Despite published evidence and pragmatic advice from the British Society of Paediatric Gastroenterology Hepatology and Nutrition and National Institute for Health and Care Excellence, significant differences remain in diagnostic and ongoing management practice and are opportunities for research and directive evidence‐based follow‐up guidance.
In-utero exposure to zidovudine-containing antiretroviral therapy and clonal hematopoiesis in HIV-exposed uninfected newborns
Authors: Lin Shu-Hong , Wang Youjin , Hartley Stephen W. , Karyadi Danielle M. , Lee Olivia W. , Zhu Bin , Zhou Weiyin , Brown Derek W. , Beilstein-Wedel Erin , Hazra Rohan , Kacanek Deborah , Chadwick Ellen G. , Marsit Carmen J. , Poirier Miriam C. , Brummel Sean S. , Chanock Stephen J. , Engels Eric A. , Machiela Mitchell J. 
Published: March 2021

Objective:
Zidovudine (ZDV) has been extensively used in pregnant women to prevent vertical transmission of HIV but few studies have evaluated potential mutagenic effects of ZDV during fetal development.

Design:
Our study investigated clonal hematopoiesis in HIV-exposed uninfected (HEU) newborns, 94 of whom were ZDV-exposed and 91 antiretroviral therapy (ART)-unexposed and matched for potential confounding factors.

Methods:
Utilizing high depth sequencing and genotyping arrays, we comprehensively examined blood samples collected during the first week after birth for potential clonal hematopoiesis associated with fetal ZDV exposure, including clonal single nucleotide variants (SNVs), small insertions and deletions (indels), and large structural copy number or copy neutral alterations.

Results:
We observed no statistically significant difference in the number of SNVs and indels per person in ZDV-exposed children (adjusted ratio [95% confidence interval, CI] for expected number of mutations = 0.79 [0.50--1.22], P = 0.3), and no difference in the number of large structural alterations. Mutations in common clonal hematopoiesis driver genes were not found in the study population. Mutational signature analyses on SNVs detected no novel signatures unique to the ZDV-exposed children and the mutational profiles were similar between the two groups.

Conclusion:
Our results suggest that clonal hematopoiesis at levels detectable in our study is not strongly influenced by in-utero ZDV exposure; however, additional follow-up studies are needed to further evaluate the safety and potential long-term impacts of in-utero ZDV exposure in HEU children as well as better investigate genomic aberrations occurring late in pregnancy.