bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Suhu Penyimpanan Obat Kapsul Komersil Terhadap Organoleptik
Authors: Diah Ningsih Venny 
Published: November 2021

Medicinal products have quality standards or qualities that are very important to determine the therapeutic effect of a drug. One of the external factors that affect drug quality is temperature, because temperature can affect the instability of the quality of a drug product. This study aims to determine the effect of storage temperature of commercial capsule drugs on organoleptic. The research method uses a quantitative approach and experimental method by measuring the ascorbic acid content of the vitamin C tablet drug samples, with variations in temperature, namely cold (5°C), room temperature (27°C) and excessive heat (48°C) for a long time 180 minutes time. The results showed that temperature had a significant effect on the content of ascorbic acid in commercial vitamin C tablets with the results in sample I cold temperature (5°C) 101.2%, room temperature (27°C) 97.6% and overheating temperature (48°C). 90.5%. In sample II the cold temperature (5°C) was 101.8%, the room temperature (27°C) was 103.3% and the overheat temperature (48°C) was 95.3% after 180 minutes of storage.

Keywords: Temperature, Capsule Medicine, Organoleptic
ABSTRAK

Mutu atau kualitas suatu produk obat merupakan faktor penting untuk mengetahui efek terapetik dari suatu obat. Salah satu faktor eksternal yang dapat mempengaruhi mutu obat adalah suhu karena dapat mempengaruhi ketidakstabilan sifat fisikakimia senyawa aktif dalam sediaan. Penelitian ini bertujuan untuk mengetahui pengaruh suhu penyimpanan obat kapsul komersil terhadap organoleptik. Metode penelitian menggunakan pendekatan kuantitatif dan eksperimental dengan cara mengukur kadar asam askorbat dari sampel obat tablet vitamin C dengan variasi suhu yaitu dingin (5°C), suhu ruang (27°C) dan suhu panas berlebih (48°C) dengan lama waktu simpan 180 menit. Hasil penelitian menunjukkan bahwa suhu berpengaruh secara nyata terhadap kandungan asam askorbat dalam obat tablet vitamin C komersil dengan hasil pada sampel I suhu dingin (5°C) 101.2%, suhu ruang (27°C) 97.6% dan suhu panas berlebih (48°C) 90.5%. Pada sampel II suhu dingin (5°C) 101.8%, suhu ruang (27°C) 103.3% dan suhu panas berlebih (48°C) 95.3% setelah 180 menit penyimpanan.

Kata Kunci: Suhu, Obat Kapsul, Organoleptik
Comparison Of Real Costs In Type 2 Diabetes Mellitus Patients With INA-CBG'S Prices In Ina-Cbg's Regional General Hospital
Authors: Oktadiana Isma 
Published: November 2021

The mismatch between real costs and the INA-package CBG's pricing is a common difficulty in the implementation of Jamkesmas. The goal of this study is to see how much of a discrepancy there is between real costs and INA-package CBG's rates for type 2 diabetes mellitus inpatients at the Bima District Hospital, as well as to look at the factors that affect real costs. Analytic observation is a sort of study. Jamkesmas claim files and patient medical records were analyzed retrospectively. Claim files and medical records of Jamkesmas diabetes mellitus patients at the Bima District Hospital for the 2020 period with the diagnostic code INA-E-4-10-I, CBG's E-4-10-II, and E-4-10-III were the research subjects, while the study's object was claim files and medical records of Jamkesmas diabetes mellitus patients at the Bima District Hospital for the 2020 period. The data was analyzed descriptively. In addition, a one-sample test statistical analysis was performed to determine the difference between real costs and INA rates, CBG's and a bivariate correlation test to find the factors that affect real costs. The study's study showed it for severity levels I, II, and III, there is a significant cost disparity between real costs and INA-CBG rates. Severity and leght of stay are 2 parameters that influence the real cost of patient treatment.
ABSTRAK

Selisih antara harga sebenarnya dan harga paket INA CBG merupakan hambatan umum dalam pemasangan Jamkesmas. Tujuan dari penelitian ini adalah untuk mengetahui besarnya gap antara biaya riil dengan tarif CBG paket INA untuk pasien rawat inap diabetes tipe 2 di RSUD Bima, serta faktor-faktor yang mempengaruhi biaya riil. Observasi analitik dapat dianggap sebagai jenis penelitian. Analisis retrospektif terhadap berkas klaim Jamkesmas dan informasi medis pasien dilakukan. Berkas klaim dan rekam medis pasien diabetes mellitus Jamkesmas di RSUD Kabupaten Bima Periode 2020 dengan kode diagnostik INA-E-4-10-I, CBG's E-4-10-II, dan E-4-10-III adalah subjek penelitian, sedangkan objek penelitian adalah berkas klaim dan rekam medis pasien diabetes melitus Jamkesmas di RSUD Kabupaten Bima periode 2020. Data dianalisis secara deskriptif. Selain itu, statistik uji satu sampel analisis dilakukan untuk menentukan perbedaan biaya riil dengan tarif INA, CBG's, dan uji korelasi bivariat untuk menemukan faktor-faktor yang mempengaruhi biaya riil. Hasil kajian menunjukkan bahwa untuk tingkat keparahan I, II, dan III terdapat disparitas biaya yang signifikan antara biaya riil dengan tarif INA-CBG. Tingkat keparahan dan lama rawat inap adalah dua kriteria yang membuat biaya perawatan pasien yang sebenarnya.
The clinical, laboratory and prognostic characteristics of haemorrhagic stroke cases related to COVID-19 infection
Authors: Üstün Özek Sibel , Emir Canan 
Published: November 2021

Objective: Although ischemic and thrombotic vascular processes are more widely reported in COVID-19, the ratio of haemorrhagic cerebrovascular disease is lower. However, it needs to be evaluated because the mortality rate is higher in haemorrhages, and they may appear iatrogenically.
Material and Methods: Patients observed at the Prof. Dr. Cemil Taşçıoğlu City Hospital between March 11th, 2020, and March 11th, 2021, were included in the study. Cases diagnosed as consecutive full intracerebral haemorrhage and concomitant with COVID-19 were observed during the study period. This study is a cross-sectional, retrospective, and observational study.
Results: Within the 1-year period, 11 patients (7 men and 4 women) with a mean age of 64.45±18.68 years related to COVID-19 were recorded. Risk factors were high blood pressure at a frequency of 64%, diabetes mellitus at 45%, and the use of antiaggregants/anticoagulants at 36%. The ratio of male patients was 64% (n=7). The location of haemorrhage was intraparenchymal in 91% (n=10), and subdural in 9% (n=1). The mortality rate was 64%.
Conclusion: Neurologic findings that develop, especially in noncooperating and prone patients in wards and intensive care units, must be observed carefully. Caution must be exercised in prophylactic antiaggregant and anticoagulant treatment, especially in high-risk patients. Intracranial haemorrhages are important due to high mortality.
Abdominal wall skin lesions in adult morbid obese women
Authors: Kutluer Nizamettin , Yılmaz Mikail , Doğan Serhat , Öndeş Bahadır 
Published: November 2021

Objective: To present only skin lesions in the abdominal wall that we detected in morbidly obese patients and to examine them in the light of the literature.
Material and Method: Patients who applied to the general surgery outpatient clinic for bariatric surgery and who also had dermatological complaints and were referred to the dermatology outpatient clinic with the detection of skin-related complaints were retrospectively evaluated in terms of age and breast skin findings. Normal skin findings were separated into intertrigo, chronic recurrent folliculitis, eczemas, acanthosis nigricans and striae.
Results: A total of 60 obese female patients were included in the study. The mean age of the patients was 32.4 ± 8.8 years (19-53), and the mean body mass index was 42.6 ± 2.4 (40-49). Normal skin findings were present in 28.3% of the patients (17 patients). The most common finding was striae, and 60% (36 patients) had it. Then respectively, intertrigo was detected in 14 patients (23%), chronic recurrent folliculitis in 12 patients (20%), eczema in 5 patients (8.3%), and acanthosis nigricans in 2 patients (3.3%).
Conclusion: The most common findings on the abdominal wall skin of obese individuals are striae and intertrigo, and similar findings have been found in many studies in the literature.
New Paths to Online Teaching – How Can We Manage Knowledge Transfer and Make the Learning More Enjoyable?
Authors: Benedek András 
Published: November 2021

This study is based on the results from a national project initiative on digitalization, supported by methodology evidence from e-learning materials at the level of teachers’ training for vocational education institutes. Looking for the new paths to online learning We have been formulating the question for almost a decade: How can we manage the transfer of knowledge and make learning more enjoyable? For the steps forwards, the first impulses for understanding the recontextualization of vocational didactics and re-defining roles and responsibilities of the actors. Our paper deals with seeking a new method for content development and its application in vocational education and training (VET). This study recommends a kind of open framework[1] is provided by the fact that the innovation, which takes open source content development as one of the approaches of reforming teacher training for VET, is connected to a technical university of long-existing traditions. In line with the peculiarities of Hungarian VET, our research group undertook to develop methodological training in terms of complex school subjects. By applying their new concept, their concrete objective was: the methodological renewal of vocational teacher training and practical training by creating and applying complex learning content units online.
THE CONSTRUCTION OF GUILT IN EUROPEAN MEDIEVAL LAW
Authors: Сквозников Александр Николаевич 
Published: November 2021

Постоянная потребность исследователей в углубленном изучении проблем вины и ответственности определяется не только задачами совершенствования законодательства и правоприменительной практики, но и изменчивостью представлений людей об основаниях, пределах, формах и целях ответственности лица, представлений, отражающих реальный процесс исторического развития общественных отношений и практики их правового регулирования. В работе исследована деятельность средневекового законодателя по разграничению умысла и неосторожности как двух форм вины при совершении преступлений против личности, а также разграничение виновного причинения вреда от казуса. Автор пришел к выводу о том, что в источниках европейского права VIII-XVI вв. законодатель значительное место уделяет внутреннему (субъективному) отношению лица к совершенному правонарушению и его последствиям. Выявление и учет таких признаков субъективной стороны деяния, как вина, мотив и цель, существенно влиял на квалификацию деяния и назначение наказания либо приводил к освобождению от ответственности ввиду отсутствия субъективной стороны правонарушения (вины) как одного из элементов состава правонарушения. В работе показано, каким образом законодатель учитывал влияние субъективного отношения лица к совершенному деянию при установлении юридической ответственности.
The constant need of researchers for an in-depth study of the problems of guilt and responsibility is determined not only by the tasks of improving legislation and law enforcement practice, but also by the variability of people's ideas about the grounds, limits, forms and purposes of a person's responsibility, ideas that reflect the real process of the historical development of social relations and the practice of their legal regulation. The work examines the activities of the medieval legislator to differentiate intent and negligence as two forms of guilt when committing crimes against the person, as well as the differentiation of guilty harm from an incident. The author came to the conclusion that in the sources of European law of the VIII-XVI centuries. For centuries, the legislator has given a significant place to the internal (subjective) attitude of a person to a committed offense and its consequences. The identification and consideration of such signs of the subjective side of the act as guilt, motive and purpose significantly influenced the qualification of the act and the appointment of punishment, or led to release from liability due to the absence of the subjective side of the offense (guilt) as one of the elements of the offense. The work shows how the legislator took into account the influence of a person's subjective attitude to the committed act when establishing legal responsibility.
Incidencia de los Procesos Creativos en los Estudiantes de Artes Visuales
Authors: Delgado-Miranda Edison Mauricio 
Published: November 2021

En la historia de la humanidad enfocado en el arte, específicamente en el dibujo y la pintura, se da la habilidad de representar imágenes reales, ficticias o abstractas sobre una superficie, que puede ser de naturaleza muy diversa y con diferentes pigmentos. Esta investigación tuvo como objetivo el análisis e incidencia de los procesos creativos en el aprendizaje de la expresión gráfico-plástico del retrato-autorretrato en los estudiantes de primer semestre de Artes Visuales, Universidad de Pamplona. Por lo tanto, se realizó una revisión bibliográfica sobre los aspectos relevantes de la teoría estudiada, así como de los trabajos en el ámbito internacional, nacional y regional, los cuales fueron de gran utilidad para el diseño metodológico, planteamiento, estrategia y análisis de los resultados. El tipo de investigación fue cualitativo con el método fenomenológico e iniciada con una etapa de diagnóstico donde se logró establecer una población caracterizada por cinco estudiantes de primer semestre más 3 docentes que fueron de suma importancia por sus aportes. Con su posterior análisis, información y discusión los resultados llevaron a la conclusión principal: los procesos creativos sí influyeron a la hora de dibujar un rostro sabiendo como requerimiento una percepción muy aguda ya que, por este motivo, la expresión gráfico-plástica del retrato-autorretrato es muy efectiva para los que están aprendiendo a ver y dibujar.
Représentations sociales de la coopétition au niveau individuel. Le cas d’une alliance entre instituts de formation en ostéopathie
Authors: Albert-Cromarias Anne , Livertout Julien 
Published: November 2021

Si la littérature sur la coopétition est désormais abondante, peu de travaux s’intéressent aux perceptions qu’en ont les collaborateurs eux-mêmes. En complément d’articles récents sur la capacité de coopétition et sur la perception intra-organisationnelle d’une telle stratégie, le présent article s’intéresse à sa représentation sociale par les collaborateurs, en amont d’un projet de coopétition entre organisations. A travers une étude de cas, nous étudions plus spécifiquement le rapprochement de trois instituts de formation en ostéopathie. Les représentations sociales y sont repérées à l’aide d’un questionnaire d’association sémantique d’une part et d’entretiens semi-directifs d’autre part, administrés auprès de collaborateurs appartenant à différents groupes professionnels. Les résultats montrent que les représentations sociales associées à la coopétition peuvent être tout à fait positives ; ils insistent sur l’importance de s’intéresser dès l’amont à la perception d’une telle stratégie par les collaborateurs. Notre recherche contribue ainsi à la littérature sur la coopétition sur deux aspects. Tout d’abord, en s’intéressant à l’amont de la coopétition, notre recherche apporte une contribution à la fois originale – car non encore explorée – et primordiale – puisqu’il s’agit d’anticiper le degré d’acceptabilité de la coopétition par les collaborateurs eux-mêmes. De plus, notre recherche aborde la perception de la coopétition au niveau individuel, encore très peu étudiée. Plusieurs recommandations sont ainsi formulées à destination des équipes de direction qui engagent des projets coopétitifs.
Is there a relationship between investor sentiment and green finance?
Authors: Mzoughi Hela , Hchaichi Rafla , Guesmi Khaled 
Published: November 2021

Cet article examine la relation dynamique entre le marché financier des projets verts et les indices de sentiments des investisseurs (principalement l’indice de volatilité du Chicago Board Options Exchange et l’indice Bitcoin) pour la période allant du 13 octobre 2014 au 11 septembre 2020. En mettant en œuvre le vecteur modèle de correction d’erreur, nos résultats mettent en évidence un ajustement non significatif vers un équilibre de long terme entre le sentiment des investisseurs sur les marchés financiers et le soutien des projets verts. Notre étude vise à aider les investisseurs à dynamiser des portefeuilles respectueux de l’environnement et à ajuster leur stratégie d’investissement en fonction des indices de sentiment.
La communauté Nova Esperança (PR) : l'incorporation des droits des migrants internationaux et des réfugiés aux revendications des mouvements de lutte pour le logement au Brésil
Authors: Ragnini Elaine Cristina Schimtt , Pontes Daniele Regina , Faria José Ricardo Vargas de , Oliveira Márcio de 
Published: November 2021

La Communauté Nova Esperança s'est implantée en 2020 dans un espace public à la périphérie de la ville de Curitiba, capitale de l'état de Paraná, à partir des actions du Mouvement Populaire pour le Logement (MPL). La zone occupée, dont la superficie totale est de 371 420,23 m2, appartient à la Fondation d'Action Sociale, une entité publique liée à l'exécutif municipal de la ville de Curitiba. S’agissant d’une occupation, la zone est actuellement l'objet de l'action légale de reprise de possession. Face à la nécessité d'éclaircir les caractéristiques de la zone, le Parquet de l'état du Paraná a demandé à l'Université Fédérale du Paraná (UFPR) une étude technique sur les possibilités d'utilisation, d'occupation et de lotissement de la zone ainsi que sur les contraintes environnementales puisque la zone est située dans une commune d’environnement fragile. Dans cette étude, nous analysons l’environnement, les conditions générales de vie, de logement et les formes de génération de revenus d’environ 1 200 familles dont 65 % ont entre 25 et 59 ans et dont ¼ sont des immigrés particulièrement touchés par la pandémie et par la crise économique. Dans l’ensemble, nous avons identifié l'omission de l'État à l'égard des politiques de logement et de protection sociale. Dans le sens inverse, dans la communauté, les habitants préservant la forêt, organisent la collecte des déchets solides, construisent des bio digesteurs et certaines structures de bio-fosses dans le but de réduire la contamination des sols et des eaux souterraines. En outre, il y a le jardin communautaire, la cuisine collective et l’atelier de couture. La zone occupée est solution évidente au déficit de logements. En outre, la génération de revenus et les nouvelles formes de sociabilité entre brésiliens et immigrés sont des exemples qui peuvent inspirer la mise en place des politiques d’accueil et d’intégration.
Serum level of Vitamin D is associated with COVID-19 mortality rate in hospitalized patients
Authors: Ranjbar Mitra , Karbalaie Niya Mohammad Hadi , Roham Maryam , Rezaie Nader , Yadollahzadeh Mahdi , Farrokhpour Mohsen , Azimi Mehdi , Motamed Nima , Perumal Dhayaneethie , Tameshkel Fahimeh Safarnezhad , Dadras Farahnaz , Madani Nahid Hashemi , Ghanbari Behrooz , Faraji Amirhossein , Nikkhah Mehdi , Rahmani Shahrzad , Golgiri Fatemah , Emadi Seyed Yadollah , Abbasi Rowshanak , Mohseni Iman , Babaei Mohammad Reza , Eskandari Ramin , Ataee Manizhe , Panahi Mahshid , Zamani Farhad , Makiani Mahin Jamshidi , Laali Azadeh 
Published: November 2021

Background:
Due to widespread of coronavirus disease 2019 (COVID-19) infection, identification of its risk factors and clinical characteristics are important. The aim of the present study was to assess Vitamin D levels in individuals with severe acute respiratory syndrome coronavirus-19 infection and to report on its potential as a predictive marker.

Materials and Methods:
All patients, diagnosed with COVID-19 infection from February 16 to March 21, 2020, and referred to Firoozgar Hospital, Tehran, Iran, were enrolled in this study. Vitamin D analysis was undertaken on patient serum samples using a commercial kit (Pars Azmoon Co., Tehran, Iran). SPSS v. 22 was used for statistical analysis.

Results:
Vitamin D serum concentration was analyzed in a total of 317 patients whose mean age ± standard deviation was 62.05 ± 15 years and with 62.5% being male. A significant association of Vitamin D level and death was observed. Higher levels of serum Vitamin D had protection against death (odds ratio = 0.955 [95% confidence interval = 0.923–0.988], P = 0.008).

Conclusion:
As a preliminary study in the Iranian population who suffered COVID-19 disease, we identified that Vitamin D deficiency was associated with a higher death rate and intensive care unit admission.
Effect of Zingiber officinale Roscoe rhizome (ginger) capsule on postpartum pain
Authors: Mozafari Shabnam , Esmaeili Somayeh , Momenyan Somayeh , Zadeh Modarres Shahrzad , Ozgoli Giti 
Published: November 2021

Background:
Postpartum pain contributes to increased irritability and excessive stress in the mother and consequently may inhibit successful breastfeeding, reduce a mother's ability to take care of her baby, and cause an imperfect mother-baby interaction. Evidence suggests the positive effect of ginger on reduction in uterus-associated pain. The objective of this study is to investigate the effect of ginger capsules on postpartum pain.

Materials and Methods:
The present double-blinded, randomized, placebo-controlled trial was conducted in Mahdiyeh Educational Hospital, Tehran. One hundred and twenty-eight mothers having moderate-to-severe pain following vaginal delivery were included. The participants were divided into two groups (A and B). Interventions were performed every 8 h in 24 h. In the first intervention (2 h after the delivery), Group A received 500 mg of placebo capsules (containing chickpea flour) and Group B received 500 mg of Zintoma (ginger rhizome) capsules. In the second and third interventions, Group A received 250 mg placebo capsules and Group B received 250 mg Zintoma capsules. All participants received 250 mg capsules of mefenamic acid in each intervention in addition to ginger or placebo capsules. The pain severity was measured before and half an hour, an hour, and 2 h after each intervention. Statistical analysis was performed using the SPSS software version. 22. The Chi-square, Fisher's, and t tests and the GEE model were applied to assess the pain severity.

Results:
The average pain severity was not statistically significant between the groups in the beginning of the intervention (P = 0.623). The mean score of pain significantly decreased within the duration of intervention in both groups (P < 0.001); however, the pain severity was significantly lower in the intervention group as compared to the control group at any point after the intervention (P = 0.006).

Conclusion:
Ginger can be used as an effective remedy for postpartum pain relief.