bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long-Term Impact of Arteriovenous Fistula Ligation on Cardiac Structure and Function in Kidney Transplant Recipients: A 5-Year Follow-Up Observational Cohort Study
Authors: Salehi Tania , Montarello Nicholas J. , Juneja Nishant , Stokes Michael B. , Scherer Daniel J. , Williams Kerry F. , King David , Macaulay Ewan , Russell Christine H. , Olakkengil Santosh A. , Carroll Robert P. , Faull Randall J. , Teo Karen S.L. , McDonald Stephen P. , Worthley Matthew I. , Coates Patrick T. , Rao Nitesh N. 
Published: May 2021

Abstract

Key Points

Long-term follow-up of patients undergoing AVF ligation postkidney transplantation demonstrates continuing regression of LVM and LVH.There was no demonstrated negative effect of AVF ligation on long-term kidney allograft function reflected by stability of serum creatinine.There was no observed increase in mortality, nonfatal MI, or cardiac hospitalization in the AVF ligation cohort over the 5-year follow-up period.

Background
The long-term effects of arteriovenous fistula (AVF) ligation on cardiovascular structure following kidney transplantation remain uncertain. A prospective randomized, controlled trial (RCT) examined the effect of AVF ligation at 6 months on cardiovascular magnetic resonance imaging (CMR)–derived parameters in 27 kidney transplant recipients compared with 27 controls. A mean decrease in left ventricular mass (LVM) of 22.1 g (95% CI, 15.0 to 29.1) was observed compared with an increase of 1.2 g (95% CI, −4.8 to 7.2) in the control group (P<0.001). We conducted a long-term follow-up observational cohort study in the treated cohort to determine the evolution of CMR-derived parameters compared with those documented at 6 months post-AVF ligation.

Methods
We performed CMR at long-term follow-up in the AVF ligation observational cohort from our original RCT published in 2019. Results were compared with CMR at 6 months postintervention. The coprimary end point was the change in CMR-derived LVM and LVM index at long-term follow-up from imaging at 6 months postindex procedure.

Results
At a median of 5.1 years (interquartile range, 4.7–5.5 years), 17 patients in the AVF ligation group were studied with repeat CMR with a median duration to follow-up imaging of 5.1 years (IQR, 4.7–5.5 years). Statistically significant further reductions in LVM (−17.6±23.0 g, P=0.006) and LVM index (−10.0±13.0 g/m2, P=0.006) were documented.

Conclusions
The benefit of AVF ligation on LVM and LVM index regression appears to persist long term. This has the potential to lead to a significant reduction in cardiovascular mortality.
Dose-Dependent Effect of Tolvaptan on Renal Prognosis in Patients with Autosomal Dominant Polycystic Kidney Disease
Authors: Akihisa Taro , Manabe Shun , Kataoka Hiroshi , Makabe Shiho , Yoshida Rie , Ushio Yusuke , Watanabe Kentaro , Sato Masayo , Tsuchiya Ken , Mochizuki Toshio , Nitta Kosaku 
Published: May 2021

Key Points

This is the first report to describe dose dependency in the effects of tolvaptan treatment for autosomal dominant polycystic kidney disease.The weight-adjusted average daily dose of tolvaptan was found to be a factor that significantly affected the change in eGFR.If a patient shows tolerance, increasing the tolvaptan dose to the maximum should be considered.
ANALISIS FAKTOR – FAKTOR YANG MEMPENGARUHI KINERJA KEUANGAN PT. ASDP INDONESIA FERRY (PERSERO) AMBON
Authors: Pattiruhu Jozef R. 
Published: May 2021

Abstract. This study aims to test, first partially or simultaneously the factors that influence Financial Performance at PT. ASDP Indonesia Ferry (Persero) Ambon. This study uses secondary data, namely PT. ASDP Indonesia Ferry (Persero) Ambon from 2010 to 2014, and the type of research used is quantitative descriptive type. The analytical method used in this study is financial ratios and multiple regression analysis using the help of a SPSS 20.0 computer program. The results of this study indicate that the first hypothesis partially has a positive influence between the size of the company that is proxied by ln total income and financial performance that is proxied by NPM at PT. ASDP Indonesia Ferry (Persero) Ambon is 0.507, and the second hypothesis shows that there is a positive influence between the projected capital structure and DER and the financial performance proxied by NPM at PT. ASDP Indonesia Ferry (Persero) Ambon amounted to 0.570, then the third hypothesis shows a positive effect between the company's growth which is proxied by sales turnover and financial performance that is proxied by NPM at PT. ASDP Indonesia Ferry (Persero) Ambon of 0.851. PT. ASDP Indonesia Ferry (Persero) in running its business must be more effective, efficient and economical and pay attention to factors that affect financial performance. This is very important because it can increase Net Profit Margin. Abstrak. Penelitian ini bertujuan untuk menguji, pertama secara parsial maupun simultan faktor – faktor yang berpengaruh terhadap Kinerja Keuangan Pada PT. ASDP Indonesia Ferry (Persero) Ambon. Penelitian ini menggunakan data sekunder yakni laporan keuangan PT. ASDP Indonesia Ferry (Persero) Ambon periode 2010 sampai dengan tahun 2014, serta Jenis penelitian yang digunakan adalah jenis deskritf kuantitatif. Metode analisa yang digunakan dalam penelitian ini adalah rasio keuangan serta analisis regresi berganda dengan menggunakan bantuan program komputer SPSS 20.0. Hasil penelitian ini menunjukan bahwa hipotesis pertama secara parsial terdapat pengaruh positif antara ukuran perusahaan yang diproksikan dengan ln total pendapatan dengan kinerja keuangan yang diproksikan dengan NPM pada PT. ASDP Indonesia Ferry (Persero) Ambon sebesar 0,507, dan hipotesis kedua menunjukkan bahwa terdapat pengaruh positif antara struktur modal yang diproyeksikan dengan DER dengan kinerja keuangan yang diproksikan dengan NPM pada PT. ASDP Indonesia Ferry (Persero) Ambon sebesar sebesar 0,570, selanjutnya hipotesis ketiga menunjukkan pengaruh positif antara pertumbuhan perusahaan yang diproksikan dengan sales turnover dengan kinerja keuangan yang diproksikan dengan NPM pada PT. ASDP Indonesia Ferry (Persero) Ambon sebesar 0,851. PT. ASDP Indonesia Ferry (Persero) dalam menjalankan usahanya harus lebih efektif, efisien dan ekonomis dan memperhatikan faktor-faktor yang mempengaruhi kinerja keuangan. Hal ini sangat penting karena dapat meningkatkan Net Profit Margin.
Menguji Strategi Desa Wisata dalam Membangun Keunggulan Bersaing di Era Revolusi Industri 4.0
Authors: Deddy Rahmat I Gede 
Published: May 2021

Abstract: This research aims to determine and test the effectiveness of the role of the village government in creating a Tourism Village strategy to build competitive advantage in the Era of Industry Revolution 4.0 and to find out the factors that hinder and influence the role of the village government in managing the village of Blimbingsari Tourism Village which is a Special Interest Tourism Village (Spiritual). This research used descriptive qualitative method. The informants in this research were the Headman of Blimbingsari, Village Secretary, BUMDes Treasurer, Secretary of the Tourism Committee, Homestay Owners, Village Community Leaders and Academics. The technique of data collection is done by using triangulation technique (combined), the results of qualitative research emphasize the quality of the meaning of good research.The research results obtained by researchers from interviews, observations, and documentation are the role of the Blimbingsari Tourism Village Government to be carried out well. The Blimbingsari Tourism Village Government has a good role as a stabilizer, innovator and motivator. The provision of internet infrastructure and human resource development is a factor in the development of Blimbingsari tourism village in building competitiveness in the era Industry Revolution 4.0. Abstrak: Penelitian ini bertujuan untuk mengetahui dan menguji efektifitas peran pemerintah desa dalam menciptakan strategi Desa Wisata untuk membangun keunggulan bersaing di Era Revolusi Industri 4.0 serta mengetahui faktor-faktor yang menghambat dan mempengaruhi peran pemerintah desa dalam pengelolaan desa Desa Wisata Blimbingsari yang merupakan Desa Wisata Minat Khusus (Rohani). Penelitian ini menggunakan metode deskriptif kualitatif. Informan dalam penelitian ini yaitu Perbekel Desa Blimbingsari, Sekretaris Desa, Bendahahara BUMDes, Sekretaris Komite Pariwisata, Pemilik Homestay, Tokoh Masyarakat Desa dan Akademisi. Teknik pengumpulan data dilakukan dengan teknik triangulasi (gabungan), hasil penelitian kualitatif lebih menekankan pada kualitas makna penelitian yang baik.Hasil penelitian yang didapat peneliti dari wawancara, observasi, dan dokumentasi adalah peran Pemerintah Desa Wisata Blimbingsari dilakukan dengan baik. Pemerintah Desa Wisata Blimbingsari memiliki peran yang baik sebagai stabilitator, innovator dan motivator. Pengadaan infrastuktur internet dan pengembangan sumber daya manusia menjadi faktor pada pengembangan desa wisata Blimbingsari dalam membangun daya saing di era Revolusi Industri 4.0.
Digital Transformation of Public Administration Based on Competence Models
Authors: Vatlina L. V. 
Published: May 2021

Aim. The presented study aims to determine the peculiarities of introducing digital tools in public administration using different types of competencies.Tasks. The author describes major prerequisites for the transformation of the public sector in the context of digitalization; analyzes modern digital technologies and the mechanism of their implementation in public services using digital platforms, assesses their role, and identifies obstacles to the digital transformation of public administration.Methods. This study uses general scientific methods, such as the monographic method, analysis and synthesis, induction and deduction, description, and applied methods of structural, systems, and comparative economic analysis.Results. Digital transformation of the public administration system changes the understanding of management from management as execution of functions to management as a network of relationships between the state and its citizens. Reformation of the public administration model based on the implementation of digital solutions forms the new public administration concept. However, the results of the public administration system’s reformation using digital platforms are ambiguous and require study. One of the main obstacles to the formation of a “digital government” is the lack of competent specialists and qualified personnel skilled in the field of information technology (IT), Internet of Things, artificial intelligence, etc. These and other technologies are vital for the formation of a high-quality public administration system. Furthermore, the new information reality places increased demands on the skills of modern public officials, whose level of competence largely determines the quality of management. This study identifies and analyzes the necessary competencies of employees involved in the public administration system at different levels.Conclusions. Over time, digital transformation of public administration will become more evident and meaningful. It can be assumed that digitalization will make it possible to leave behind subjective decisions of individual public officials, improving the quality of provided services and reducing costs as much as possible. Digital transformation of public administration is not limited to the automation and optimization of some processes in the execution of public functions, as it also involves the implementation of modern information and communication technology (ICT) systems to improve the quality of the public administration system as a whole.
Impact of the COVID-19 Pandemic on International Negotiations
Authors: Plotnikov D. M. , Funikova E. S. 
Published: May 2021

Aim. The presented study aims to analyze factors affecting the way international negotiations are organized and conducted in the context of the COVID-19 pandemic.Tasks. The authors determine the positive and negative consequences of the pandemic for international negotiations and predict further development of the situation in this area.Methods. This study uses general scientific methods of cognition to examine the problem of reorganization of business activity in various aspects and identify characteristic trends in the current economic situation.Results. The coronavirus pandemic has had a strong impact on the daily lives of people, their interactions, and business communication. COVID-19 has led to significant transformations in business communication, emergence and modernization of various services for online interaction, including for conducting business negotiations. It is against this background that the attention to cybersecurity issues as a threat in the transition to online communication has increased.Conclusions. Examination of the impact of the COVID-19 pandemic on the way international negotiations are organized and conducted makes it possible not only to identify factors affect ing the transformation of all activities, but also to assess the consequences of ongoing changes and developments in the field of business communication.
Perception of Hospital Accreditation Impact among Quality Management Professionals in India: A Survey-Based Multicenter Study
Authors: Joseph Lallu , Agarwal Vijay , Raju Umashankar , Mavaji Arun , Rajkumar Princy 
Published: May 2021

ABSTRACT

Introduction
Accreditation ensures the standard of healthcare, yet accreditation effects on service quality are much debated. Some perceive it as improving quality and organizational performance, whereas others see it as overly bureaucratic and time-consuming, so adding it has limited advantage. The aim of the present study was to understand the perception of hospital staff working in quality management (i.e., doctors, nurses, and administrators) on accreditation, and determine whether years of accreditation have had any impact on their perception.

Methods
This was a cross-sectional, descriptive, data-based study initiated by the Consortium of Accredited Healthcare Organizations. It consisted of primary data obtained in form of responses to a 30-item questionnaire and collected from 415 respondents. A probability (p) value of less than 0.05 was considered statistically significant.

Results
For all 30 items, a significantly greater number of participants had a favorable response (p &lt; 0.001). A greater number of administrators, as compared with doctors and nurses, responded positively on the impact of accreditation (p &lt; 0.05). Participants from hospitals with 1–4 years of accreditation, as compared with participants from hospitals with 4–12 years of accreditation, gave a favorable response (p &lt; 0.05).

Conclusion
One of the most important hurdles to implementing accreditation programs is the dilemma of healthcare professionals, especially senior hospital staff, regarding the positive impact of accreditation. The need to educate healthcare professionals about the potential benefits of accreditation, which should resolve any cynical attitude of healthcare professionals towards accreditation, is of utmost importance.
recorrido por nuestra experiencia en la inclusión de software dinámico en el diseño de materiales didácticos
Authors: Soto Munguía José Luis , Romero Félix César Fabián 
Published: May 2021

Resumen
Se presentan aquí algunas de las experiencias en el uso de software de matemáticas dinámicas para el diseño de materiales y actividades didácticas. Partiendo del uso de Cabri fuera del aula, como las exploraciones gráficas de un profesor sobre temas avanzados para explorar los alcances del software, se generó toda una línea de trabajo en Matemática Educativa, pasando por la exploración novedosa de temas clásicos en matemáticas, al estudio de dificultades de aprendizaje y propuestas para su superación, culminando en una propuesta metodológica para el diseño de propuestas de enseñanza apoyadas en esta tecnología. Se ilustran algunos de los proyectos más representativos en esta línea de trabajo, así como algunas de las dificultades técnicas y didácticas que se han ido superando. A modo de conclusión, se presentan algunos ejemplos del proyecto que esta línea actualmente promueve.
Hubungan Lama Pemakaian KB Suntik 3 Bulan Dengan Gangguan Menstruasi di BPS D Purba Desa Girsang
Authors: Sinaga Rany Angggina Putri 
Published: May 2021

Kontrasepsi suntik 3 bulan merupakan salah satu cara untuk mencegah terjadinya kehamilan dengan suntikan yang mengandung hormon. Salah satu efek samping dari metode kontasepsi adalah adanya gangguan menstruasi pada penggunaan jangka panjang. Tujuan penelitian ini adalah untuk mengetahui hubungan antara lama pemakaian KB suntik 3 bulan dengan gangguan menstruasi pada akseptor KB suntik 3 bulan di BPS D Purba Desa Girsang . Metode Penelitian ini yaitu survei analitik dengan pendekatan cross sectional. Sampel adalah Akseptor KB suntik 3 bulan aktif yang mendapatkan palayanan di BPS Purba sebanyak 53 responden. Cara pengambilan sampel dengan teknik total sampling. Teknik pengumpulan data menggunakan data primer dan kuesioner. Analisis data menggunakan Chi-square α = 0,05. Hasil uji chi-square yaitu p value = 0.003. Kesimpulan dari penelitian tersebut adalah terdapat hubungan yang signifikan antara lama pemakaian alat kontrasepsi KB suntik 3 bulan dengan gangguan menstruasi di BPS D Purba Desa Girsang . Diharapkan bagi bidan memberikan pengetahuan dan konseling kepada calon akseptor atau akseptor baru mengenai efek samping serta resiko yang dapat terjadi setelah pemakaian yang lama.Kata Kunci: Lama pemakaian, KB suntik 3 bulan, Gangguan Menstruasi.
Penggunaan Media Komunikasi Dalam Penyampaian Pesan Tentang Stunting pada Mahasiswa Non Kesehatan
Authors: Ratih Susiana Dewi , Prikhatina Ratih Agustin , Manikam Ratna Mutu 
Published: May 2021

Stunting adalah kondisi gagal tumbuh pada anak balita akibat kekurangan gizi kronis terutama pada 1.000 Hari Pertama Kehidupan (HPK). Penyampaian informasi pada masyarakat menjadi penting, mengingat RPJMN 2020-2024 penekanan angka stunting ditargetkan menjadi 19% pada 2024 dari 27.7 % data riset nasional tahun 2019. Salah satu upaya untuk membantu turunnya angka stunting adalah dengan pemberian edukasi melalui berbagai media komunikasi. Metode yang digunakan yaitu dengan membuat video penyuluhan oleh mahasiswa S1 Gizi sebagai komunikator dan di unggah di Youtube. Pesan yang disampaikan adalah informasi tentang stunting, komunikan (responden) adalah mahasiswa dari program studi non kesehatan. Umpan balik diperoleh melalui pengisian kuesioner sebelum dan sesudah menonton video yang disebarkan melalui Whattapps. Data dianalisis untuk mengetahui perbedaan pemahaman sebelum dan sesudah menonton video penyuluhan. Teknik analisis data menggunakan uji paired sample t-test. Responden yaitu mahasiswa prodi non kesehatan Universitas MH. Thamrin Jakarta dan Universitas Singa Perbangsa Karawang. Hasil penyuluhan memperlihatkan ada perbedaan signifikan pemahaman responden dan kenaikan nilai test sebelum dan sesudah menonton video penyuluhan. Penyuluhan menggunakan video yang di unggah di Youtube dapat digunakan sebagai media dalam penyampaian pesan tentang stunting. Untuk selanjutnya diharapkan bisa dikembangkan video dan kuesioner yang lebih menarik dan lebih komunikatif, serta lebih melibatkan mahasiswa dalam kegiatannya.Kata Kunci: Stunting, Penyuluhan, Media Komunikasi.
Професійна підготовка майбутніх педагогічних працівників у сфері дошкільної освіти до роботи з дітьми у різновіковій групі
Authors: Марчук Оксана , Мельничук Лілія , Шкабаріна Маргарита 
Published: May 2021

У статті розроблено модель підготовки майбутніх педагогічних працівників у сфері дошкільної освіти до роботи з дітьми у різновіковій групі. Обґрунтовано важливість підготовки майбутніх вихователів до роботи з дошкільниками в умовах різновікової групи. Проаналізовано праці сучасних науковців з досліджуваної проблеми. Пояснено, що поняття «моделювання» є широким і не­достатньо конкретизованим. Встановлено, що принципи моделювання і планування спе­цифічно відображають, з одного боку, принципи управління, а з іншого – особливості планування як попередньої стадії та функції процесу управління. Розроблена авторська модель професійної підготовки майбутніх вихователів до роботи у різновікових групах базується на ідеях особистісно-діяльнісного, ресурсного та інтеграційного підходів до педагогічної діяльності студентів. Акцентовано увагу на необхідності побудови освітнього процесу на основі інтеграції навчальних дисциплін із дисциплінами методич­но-практичної підготовки, необхідних для подальшої організаційної та творчої педагогічної діяльності майбутніх вихователів. Виокремлено три етапи підготовки майбутніх педагогічних працівників у сфері дошкільної освіти. Представлено шляхи вдосконалення фахової підготовки майбутніх вихователів до роботи із дошкільниками в групах, де навчаються діти різного віку.
Foreign Direct Investment, Indeks Kemudahan Berusaha, Dan Tarif Pajak Penghasilan Negara-Negara ASEAN
Authors: Lim Setiadi Alim 
Published: May 2021

The inflow of Foreign Direct Investment is needed by all countries in the world tobe used as a catalyst to achieve the goals of sustainable development in allaspects of a country's life. Countries in the Southeast Asia Region that aremembers of ASEAN also need Foreign Direct Investment. The success of acountry in attracting Foreign Direct Investment inflows is determined by manyfactors, including the ease of doing business and the income tax rate. In thisstudy, a comparative study was conducted between the success of ASEANcountries in obtaining Foreign Direct Investment inflows with the success ofachieving a high index of ease of doing business and the use of competitiveincome tax rates. The comparison was only made between 10 ASEAN membercountries from 11 ASEAN member countries, because of the difficulty in collecting data from 1 other ASEAN member country, namely Timor Leste. The results showed that Singapore succeeded in attracting the largest Foreign DirectInvestment inflows among other ASEAN countries, amounting to 59.10% of thetotal Foreign Direct Investment inflows from ASEAN countries. Singapore'ssuccess in attracting the largest Foreign Direct Investment inflow among otherASEAN countries is directly proportional to its achievement in obtaining the bestease of doing business index and the lowest income tax rate compared to otherASEAN countries. Meanwhile, for other ASEAN countries, there is no visiblecomparison between the success of obtaining Foreign Direct Investment with theease of doing business index and the Income Tax rate.
Enseñanza-Aprendizaje Del Sistema Braille En El Estado de Hidalgo
Authors: Bautista Alemán Nancy Angélica , Morales Cordero Lizbeth , Flores Salinas Cruz Alejandro 
Published: May 2021

A través de la investigación se identifican los principales elementos implicados en el Sistema Braille y al mismo tiempo se determina en qué consiste.
De acuerdo al seguimiento del método cualitativo que se utilizó, se pudo conocer el motivo por el cual las personas optan por estudiar el Sistema Braille, siendo éste un sistema óptimo de aprendizaje para las personas que presentan debilidad visual o ceguera y las cuales bajo estas condiciones desarrollan más el sentido del tacto.
El lugar donde se realizó este estudio es en el área Braille que se encuentra ubicada en la Biblioteca del Estado, se observó cómo son impartidas las clases, cómo son los alumnos, cuál es el material que utilizan y la manera en que los beneficia el aprender y dominar dicho sistema.