bluuebunny/crossref_metadata_2025_split huggingface dataset:
Why do consumers not switch? An experimental investigation of a search and switch model
Authors: Buso Irene Maria , Hey John 
Published: May 2021

AbstractSearch and switching costs are two market frictions that are well known in the literature for preventing people from switching to a new and cheaper provider. Previous experimental literature has studied these two frictions in isolation. However, field evidence shows that these two frictions frequently occur together. Recently, a theoretical framework has been developed (Wilson in Eur Econ Rev 56(6):1070–1086) which studies the interplay between these two costs. We report on an experiment testing this theory to see if individual behaviour with search and switching costs is in line with the theoretical predictions derived from the optimal choice rule of Wilson. The results show the crucial role of the search strategy: not only, according to Wilson model, the search cost has a greater deterrent impact on search than the switching costs, but also the sub-optimality of the search strategy is the major source of sub-optimality in the switching behaviour.
Terrain classification and adaptive locomotion for a hexapod robot Qingzhui
Authors: Zhao Yue , Gao Feng , Sun Qiao , Yin Yunpeng 
Published: May 2021

AbstractLegged robots have potential advantages in mobility compared with wheeled robots in outdoor environments. The knowledge of various ground properties and adaptive locomotion based on different surface materials plays an important role in improving the stability of legged robots. A terrain classification and adaptive locomotion method for a hexapod robot named Qingzhui is proposed in this paper. First, a force-based terrain classification method is suggested. Ground contact force is calculated by collecting joint torques and inertial measurement unit information. Ground substrates are classified with the feature vector extracted from the collected data using the support vector machine algorithm. Then, an adaptive locomotion on different ground properties is proposed. The dynamic alternating tripod trotting gait is developed to control the robot, and the parameters of active compliance control change with the terrain. Finally, the method is integrated on a hexapod robot and tested by real experiments. Our method is shown effective for the hexapod robot to walk on concrete, wood, grass, and foam. The strategies and experimental results can be a valuable reference for other legged robots applied in outdoor environments.
Frequency-domain loss function for deep exposure correction of dark images
Authors: Yadav Ojasvi , Ghosal Koustav , Lutz Sebastian , Smolic Aljosa 
Published: May 2021

AbstractWe address the problem of exposure correction of dark, blurry and noisy images captured in low-light conditionsin the wild. Classical image-denoising filters work well in the frequency space but are constrained by several factors such as the correct choice of thresholds and frequency estimates. On the other hand, traditional deep networks are trained end to end in the RGB space by formulating this task as an image translation problem. However, that is done without anyexplicitconstraints on the inherent noise of the dark images and thus produces noisy and blurry outputs. To this end, we propose a DCT/FFT-based multi-scale loss function, which when combined with traditional losses, trains a network to translate the important features for visually pleasing output. Our loss function is end to end differentiable, scale-agnostic and generic; i.e., it can be applied to both RAW and JPEG images in most existing frameworks without additional overhead. Using this loss function, we report significant improvements over the state of the art using quantitative metrics and subjective tests.
Dihydroceramide Desaturase Functions as an Inducer and Rectifier of Apoptosis: Effect of Retinol Derivatives, Antioxidants and Phenolic Compounds
Authors: Alsanafi Mariam , Brown Ryan D. R. , Oh Jeongah , Adams David R. , Torta Federico , Pyne Nigel J. , Pyne Susan 
Published: May 2021

AbstractDihydroceramide desaturase (Degs1) catalyses the introduction of a 4,5-trans double bond into dihydroceramide to form ceramide. We show here that Degs1 is polyubiquitinated in response to retinol derivatives, phenolic compounds or anti-oxidants in HEK293T cells. The functional predominance of native versus polyubiquitinated forms of Degs1 appears to govern cytotoxicity. Therefore, 4-HPR or celecoxib appear to stimulate the de novo ceramide pathway (with the exception of C24:0 ceramide), using native Degs1, and thereby promote PARP cleavage and LC3B-I/II processing (autophagy/apoptosis). The ubiquitin-proteasomal degradation of Degs1 is positively linked to cell survival via XBP-1s and results in a concomitant increase in dihydroceramides and a decrease in C24:0 ceramide levels. However, in the case of 4-HPR or celecoxib, the native form of Degs1 functionally predominates, such that the apoptotic programme is sustained. In contrast, 4-HPA or AM404 do not produce apoptotic ceramide, using native Degs1, but do promote a rectifier function to induce ubiquitin-proteasomal degradation of Degs1 and are not cytotoxic. Therefore, Degs1 appears to function both as an ‘inducer’ and ‘rectifier’ of apoptosis in response to chemical cellular stress, the dynamic balance for which is dependent on the nature of chemical stress, thereby determining cytotoxicity. The de novo synthesis of ceramide or the ubiquitin-proteasomal degradation of Degs1 in response to anti-oxidants, retinol derivatives and phenolic compounds appear to involve sensors, and for rectifier function, this might be Degs1 itself.
Follicular Epithelial Dysplasia as Hashimoto Thyroiditis-Related Atypia: a Series of 91 Specimens
Authors: Kholová Ivana , Kalfert David , Lintusaari Jarkko , Rajakorpi Erja , Ludvíková Marie 
Published: May 2021

AbstractFollicular epithelial dysplasia (FED) is described as Hashimoto thyroiditis-related atypia and is thought to be a possible precancerous lesion. Dysplasia as an interface between normal state and carcinoma is described in a wide range of diseases and carcinogenesis chains. On the other hand, inflammation-related atypia and cancerogenesis is also widely studied. In this study, we retrospectively analyzed 91 specimens of thyroid gland surgical resections with FED during a 10-year-period at the university hospital pathology department. The study population consisted of 68 females and 15 males aged between 22 and 86 years. The preoperative cytology diagnoses had mainly been in the indeterminate categories with prevailing AUS/FLUS results in the FED-only group (p = 0.005) and suspicious for malignancy and malignant in the group with FED plus adjacent malignancy. The decision for surgery was malignancy related in 48.2% of the cases. The lesions were sized 0.1–3.5 mm and multifocal in 45.1% of the cases. Immunohistochemically, the atypical cells were cyclin D1-positive in 67.5%, galectin-3 in 72.7%, CK19 in 85.7%, and HBME-1 in 87.0% of cases. In conclusion, FED is suggested to be a pathogenetic link between inflammation-related atypia and papillary carcinoma and thus a premalignant precursor of papillary carcinoma in HT as 36.1% of the specimens contained also papillary carcinoma in the present study. Both histopathological nuclear features and the immunoprofile of FED are widely shared with that of papillary carcinoma.
Control of Carbon Dioxide Sequestration by Mechanical Activation of Red Mud
Authors: Mucsi Gábor , Halyag Nóra , Kurusta Tamás , Kristály Ferenc 
Published: May 2021

Abstract
Mineral carbonation is a potentially attractive sequestration technology for the permanent safe disposal and immobilization of CO2. In this technology, CO2 is chemically reacted with calcium, sodium, and magnesium containing materials to form thermodynamically stable and environmentally harmless minerals, usually carbonates. In our research, mechanical activation of red mud was carried out in order to enhance its reactivity by means of mechanochemical reactions (surface activation), and its sequestration behaviour was investigated using carbon dioxide gas at 25 °C temperature and at high pressure (5 bar) in an autoclave. The reacted red mud was characterized by Fourier-transformed infrared spectrometer, scanning electron microscopy, X-ray diffraction, laser particle size analyzer, BET specific surface area measurement, and pH measurement. It was found that mechanical activation improved the CO2 sequestration ability by 1.7 wt% of red mud, as demonstrated by the above investigations. The pH of red mud slurry can be lowered by reacting it with carbon dioxide. During our measurements, the pH of the suspension decreased from 10 to 6.81. Furthermore, the carbonation process can be successfully used to decrease the amount of harmful PM10 (particles with a diameter of 10 μm or less) and PM2.5 (particles with a diameter of 2.5 μm or less) fraction. The proportion of 10 μm particles can be reduced by 40% and that of 2.5 μm by 20%.

Graphic Abstract
Mixed Lithium and Sodium Ion Aprotic DMSO Electrolytes for Oxygen Reduction on Au and Pt Studied by DEMS and RRDE
Authors: Hegemann M. , Bawol P. P. , Köllisch-Mirbach A. , Baltruschat H. 
Published: May 2021

AbstractIn order to advance the development of metal-air batteries and solve possible problems, it is necessary to gain a fundamental understanding of the underlying reaction mechanisms. In this study we investigate the oxygen reduction reaction (ORR) and oxygen evolution reaction (OER, from species formed during ORR) in Na+ containing dimethyl sulfoxide (DMSO) on poly and single crystalline Pt and Au electrodes. Using a rotating ring disk electrode (RRDE) generator collector setup and additional differential electrochemical mass spectrometry (DEMS), we investigate the ORR mechanism and product distribution. We found that the formation of adsorbed Na2O2, which inhibits further oxygen reduction, is kinetically favored on Pt overadsorption on Au. Peroxide formation occurs to a smaller extent on the single crystal electrodes of Pt than on the polycrystalline surface. Utilizing two different approaches, we were able to calculate the heterogeneous rate constants of the O2/O2− redox couple on Pt and Au and found a higher rate for Pt electrodes compared to Au. We will show that on both electrodes the first electron transfer (formation of superoxide) is the rate-determining step in the reaction mechanism. Small amounts of added Li+ in the electrolyte reduce the reversibility of the O2/O2− redox couples due to faster and more efficient blocking of the electrode by peroxide. Another effect is the positive potential shift of the peroxide formation on both electrodes. The reaction rate of the peroxide formation on the Au electrode increases when increasing the Li+ content in the electrolyte, whereas it remains unaffected on the Pt electrode. However, we can show that the mixed electrolytes promote the activity of peroxide oxidation on the Pt electrode compared to a pure Li+ electrolyte. Overall, we found that the addition of Li+ leads to a Li+-dominated mechanism (ORR onset and product distribution) as soon as the Li+ concentration exceeds the oxygen concentration.
Graphical abstract
Markets and institutional fields: foundational concepts and a research agenda
Authors: Mountford Nicola , Geiger Susi 
Published: May 2021

AbstractWe borrow the notion of field from institutional theory to think through how markets and their ‘outsides’–or at least one particular manifestation of an ‘outside’–stand in a dynamic and interactive relationship. We distinguish the field and the market in terms of issues versus exchange and identity versus position. We argue that the lack of clarity as to how fields and markets differ, relate, overlap, and are bounded, jeopardizes our ability to address important societal debates concerning the roles of markets within and across other areas of social life. It also hinders a consolidation of insights across different approaches to studying markets, even though researchers from different disciplines often address similar concerns. Key questions for which both conceptual and analytical clarity are essential include how markets and their ‘outsides’ (here: fields) intersect; whether and how diverse sets of actors interact, work, and migrate between fields and markets; and what dynamics may be observable between field and market. We provide four illustrative examples of field/market relationships and a theoretical, methodological, and empirical research agenda for future research into markets and their ‘outsides’.
Groundwater vulnerability risk assessment in south Darb El Arbaein, south Western Desert
Authors: ElKashouty Mohamed 
Published: May 2021

AbstractGroundwater resources in the south Darb El Arbaein are currently threatened by agricultural impact and rock water interaction associated with over exploitation. Planning of Nubian sandstone aquifer is required, especially in this new invest area. It is implemented by GIS to establish vulnerability areas and to evaluate protocol plans for hydrogeological parameters and soil. The TDS concentration ranged from 750 to 1350 ppm, confirms the impact of non-point source (agricultural activity). It is because recharging Nile water has TDS concentration of 100–300 ppm. Aquifer vulnerability delineation areas by lithogenic and anthropogenic sources have been recently highlighted for water resources systems planning and management. The correlation among hydrogeological, geological, and hydrogeochemical characteristics was discussed and achieved. Ten stratified beds were matched by GIS with specified average weights to them according to their relative importance for groundwater vulnerability. The chosen layers are TDS, aquitard thickness, water depth, hydraulic conductivity, transmissivity, slope, total hardness (TH), sodium adsorption ratio (SAR), discharge rate (Q), and screen length. The groundwater impact distribution reflect five categories ranged from no to excellent aquifer potential levels. Class I (very low vulnerability) was in the northern part and contains 11.1% (16.02 km2) of the area. While very high vulnerability (class V) was in southeast, east, it represents 10.4% (14.96 km2). The preferred invested area was northeast rather than other areas; otherwise, the groundwater degradation enhanced. The vegetation/ or barren lands were established by band 4/band 3, band 3/band 4 ratios and composite RGB 7, 4, and 1 satellite images.
Significance of multi-objective optimization in logistics problem for multi-product supply chain network under the intuitionistic fuzzy environment
Authors: Gupta Srikant , Haq Ahteshamul , Ali Irfan , Sarkar Biswajit 
Published: May 2021

AbstractDetermining the methods for fulfilling the continuously increasing customer expectations and maintaining competitiveness in the market while limiting controllable expenses is challenging. Our study thus identifies inefficiencies in the supply chain network (SCN). The initial goal is to obtain the best allocation order for products from various sources with different destinations in an optimal manner. This study considers two types of decision-makers (DMs) operating at two separate groups of SCN, that is, a bi-level decision-making process. The first-level DM moves first and determines the amounts of the quantity transported to distributors, and the second-level DM then rationally chooses their amounts. First-level decision-makers (FLDMs) aimed at minimizing the total costs of transportation, while second-level decision-makers (SLDM) attempt to simultaneously minimize the total delivery time of the SCN and balance the allocation order between various sources and destinations. This investigation implements fuzzy goal programming (FGP) to solve the multi-objective of SCN in an intuitionistic fuzzy environment. The FGP concept was used to define the fuzzy goals, build linear and nonlinear membership functions, and achieve the compromise solution. A real-life case study was used to illustrate the proposed work. The obtained result shows the optimal quantities transported from the various sources to the various destinations that could enable managers to detect the optimum quantity of the product when hierarchical decision-making involving two levels. A case study then illustrates the application of the proposed work.
Plant Pollen Grains: A Move Towards Green Drug and Vaccine Delivery Systems
Authors: Iravani Siavash , Varma Rajender S. 
Published: May 2021

Abstract
Pollen grains and plant spores have emerged as innovative biomaterials for various applications such as drug/vaccine delivery, catalyst support, and the removal of heavy metals. The natural microcapsules comprising spore shells and pollen grain are designed for protecting the genetic materials of plants from exterior impairments. Two layers make up the shell, the outer layer (exine) that comprised largely of sporopollenin, and the inner layer (intine) that built chiefly of cellulose. These microcapsule shells, namely hollow sporopollenin exine capsules have some salient features such as homogeneity in size, non-toxic nature, resilience to both alkalis and acids, and the potential to withstand at elevated temperatures; they have displayed promising potential for the microencapsulation and the controlled drug delivery/release. The important attribute of mucoadhesion to intestinal tissues can prolong the interaction of sporopollenin with the intestinal mucosa directing to an augmented effectiveness of nutraceutical or drug delivery. Here, current trends and prospects related to the application of plant pollen grains for the delivery of vaccines and drugs and vaccine are discussed. "Image missing"
Challenges in transfer of gas-liquid reactions from batch to continuous operation: dimensional analysis and simulations for aerobic oxidation
Authors: Friedland Jens , Güttel Robert 
Published: May 2021

AbstractThe transfer of gas-liquid reactions from conventional batch processes into continuous operation using milli and micro reactors is claimed as an important step towards process intensification. Importantly, this transfer step should be realized in an early phase of process development, already, in order to minimize research efforts towards the undesired operation strategy. The main challenge of this approach, therefore, arises from lack of knowledge in the early stage of process development and the resulting system with high degrees of freedom. This contribution presents an approach to tackle this challenge by means of mathematical modelling and simulation for the aerobic oxidation of 9,10-dihydroanthracene (DHA) catalyzed by polyoxometalates (POMs) being used as example for gas-liquid reactions. The reaction was chosen as it provides sufficient complexity, since it consists of three consecutive oxidation steps of DHA and a parallel catalytic redox-cycle according to a Mars-van-Krevelen mechanism. It also provides the challenge of unknown reaction kinetics, which have been estimated in this contribution. The dimensionless balance equations for reactor modeling are derived and parametrized based on early stage experimental results obtained in batch operation mode. The discrimination between batch and continuous operation was performed by means of characteristic dimensionless numbers using the identical mathematical model for comparability reasons. The model was used to perform sensitivity studies with emphasis on the interplay between mass transfer characteristics and reaction kinetics for both the batch and continuous operation mode. The simulation results show that the performance of both operation modes mainly depend on the oxidation state of the POM catalyst, which is caused by the differences in oxygen availability. Therefore, results obtained in batch operation mode are prone to be masked by mass transfer issues, which affects catalyst and reactor development at the same time and may thus cause maldevelopments. With respect to process development it can thus be concluded that the transfer from batch to continuous operation together with mathematical modeling is important in an early phase, already, in order to detect limitations misleading the development. Finally, even simple models with roughly estimated parameters from preliminary experiments are shown to be sufficient in the early phase and can systematically be improved, in the subsequent phases.
Graphical abstract
Zero-inflated-censored Weibull and gamma regression models to estimate wild boar population dispersal distance
Authors: de Freitas Costa Eduardo , Schneider Silvana , Carlotto Giulia Bagatini , Cabalheiro Tainá , de Oliveira Júnior Mauro Ribeiro 
Published: May 2021

AbstractThe dynamics of the wild boar population has become a pressing issue not only for ecological purposes, but also for agricultural and livestock production. The data related to the wild boar dispersal distance can have a complex structure, including excess of zeros and right-censored observations, thus being challenging for modeling. In this sense, we propose two different zero-inflated-right-censored regression models, assuming Weibull and gamma distributions. First, we present the construction of the likelihood function, and then, we apply both models to simulated datasets, demonstrating that both regression models behave well. The simulation results point to the consistency and asymptotic unbiasedness of the developed methods. Afterwards, we adjusted both models to a simulated dataset of wild boar dispersal, including excess of zeros, right-censored observations, and two covariates: age and sex. We showed that the models were useful to extract inferences about the wild boar dispersal, correctly describing the data mimicking a situation where males disperse more than females, and age has a positive effect on the dispersal of the wild boars. These results are useful to overcome some limitations regarding inferences in zero-inflated-right-censored datasets, especially concerning the wild boar’s population. Users will be provided with an R function to run the proposed models.
Effects of nano-particles on cold recycled asphalt properties
Authors: Hasaninasab Shahab 
Published: May 2021

AbstractCold recycling of asphalt is an effective solution to reduce the environmental impacts of pavement construction and operation. This approach reduces the use of scarce resources and fossil fuels, and prevents the spread of greenhouse pollutants in the air. Despite its benefits, recycled asphalt does have drawbacks, some of which include nibbling, stripping, and less resistance to fatigue. The use of additives can improve the mechanical properties of recycled asphalt. In this research, the addition of Nano-lime, Nano-Alumina, and Nano-clay instead of cement, to bitumen emulsion in recycled asphalt was used to improve the properties of asphalt resilient modulus and fatigue. A comparative method was used to analyze the obtained experimental results. In this study the resilient modulus and fatigue properties of asphaltic concrete were measured. The results show that asphalt fatigue properties and resilient modulus improve significantly with the addition of different Nano-particle percentages.