bluuebunny/crossref_metadata_2025_split huggingface dataset:
Greater Sage-Grouse nest bowls buffer microclimate in a post-megafire landscape although effects on nest survival are marginal
Authors: Anthony Christopher R , Hagen Christian A , Dugger Katie M , Elmore R Dwayne 
Published: April 2021

AbstractTemperature at fine spatial scales is an important driver of nest site selection for many avian species during the breeding season and can influence nest success. Sagebrush (Artemisia spp.) communities have areas with high levels of vegetation heterogeneity and high thermal variation; however, fire removes vegetation that provides protection from predators and extreme environmental conditions. To examine the influence of microclimates on Greater Sage-Grouse (Centrocercus urophasianus) nest site selection and nest success in a fire-affected landscape, we measured black bulb temperature (Tbb) and vegetation attributes (e.g., visual obstruction) at 3 spatial scales (i.e. nest bowl, microsite, and landscape) in unburned and burned areas. Nest bowls exhibited greater buffering of Tbb than both nearby microsites and the broader landscape. Notably, nest bowls were warmer in cold temperatures, and cooler in hot temperatures, than nearby microsites and the broader landscape, regardless of burn stage. Nest survival (NS) was higher for nests in unburned areas compared to nests in burned areas (unburned NS = 0.43, 95% confidence interval [CI]: 0.33–0.54; burned NS = 0.24, 95% CI: 0.10–0.46). The amount of bare ground was negatively associated with NS, but effects diminished as the amount of bare ground reached low levels. Shrub height and visual obstruction were positively associated with NS during the entire study period, whereas minimum Tbb had a weaker effect. Our findings demonstrate that thermoregulatory selection by Greater Sage-Grouse at nest sites had marginal effects on their NS. However, given that increases in vegetation structure (e.g., shrub height) provide thermal refuge and increase NS, vegetation remnants or regeneration in a post-fire landscape could be critical to Greater Sage-Grouse nesting ecology.
Beyond refueling: Investigating the diversity of functions of migratory stopover events
Authors: Linscott Jennifer A , Senner Nathan R 
Published: April 2021

AbstractStopovers comprise a significant proportion of the time that many birds spend migrating, and researchers have long relied on these events to define and classify broader migratory strategies. Analyses of stopovers often assume that individuals stop primarily or exclusively in order to replenish energy stores, but other non-fueling behaviors have also been described during stopover events and can influence stopover incidence and duration. Here, we discuss the growing demand for understanding these non-fueling behaviors and for restoring the inherent behavioral complexity to stopover events. We begin by describing how light-weight tracking technologies allow researchers to follow individuals along their entire migratory journeys, capturing stopovers that controvert the traditional stop–refuel–resume paradigm. We then discuss 5 well-identified non-fueling behaviors—recovering, sleeping, waiting, information gathering, and social interactions—and examine how including these behaviors can alter interpretations of individual movement paths. Finally, we outline emerging directions for identifying these behaviors and look to larger implications for population management and site conservation along migratory flyways.
Female and male song exhibit both parallel and divergent patterns of cultural evolution: A long-term study of song structure and diversity in tropical wrens
Authors: Graham Brendan A , Heath Daniel D , Mennill Daniel J 
Published: April 2021

Abstract
Animal culture changes over time through processes that include drift, immigration, selection, and innovation. Cultural change has been particularly well-studied for animal vocalizations, especially for the vocalizations of male animals in the temperate zone. Here we examine the cultural change in the vocalizations of tropical Rufous-and-white Wrens (Thryophilus rufalbus), quantifying temporal variation in song structure, song type diversity, and population-level distribution of song types in both males and females. We use data from 10 microsatellite loci to quantify patterns of immigration and neutral genetic differentiation over time, to investigate whether cultural diversity changes with rates of immigration. Based on 11 yr of data, we show that the spectro-temporal features of several widely-used persistent song types maintain a relatively high level of consistency for both males and females, whereas the distribution and frequency of particular song types change over time for both sexes. Males and females exhibit comparable levels of cultural diversity (i.e. the diversity of song types across the population), although females exhibit greater rates of cultural change over time. We found that female changes in cultural diversity increased when immigration is high, whereas male cultural diversity did not change with immigration. Our study is the first long-term study to explore cultural evolution for both male and female birds and suggests that cultural patterns exhibit notable differences between the sexes.
High-intensity flight feather molt and comparative molt ecology of warblers of eastern North America
Authors: Mumme Ronald L , Mulvihill Robert S , Norman David 
Published: April 2021

Abstract
Rapid high-intensity molt of flight feathers occurs in many bird species and can have several detrimental consequences, including reductions in flight capabilities, foraging performance, parental care, and plumage quality. Many migratory New World warblers (family Parulidae) are known to have intense remigial molt, and recent work has suggested that simultaneous replacement of the rectrices may be widespread in the family as well. However, the phylogenetic distribution of simultaneous rectrix molt, and high-intensity flight feather molt more generally, has not been systematically investigated in warblers. We addressed this issue by examining flight feather molt in 13 species, representing 7 different warbler genera, at Powdermill Avian Research Center in southwestern Pennsylvania, USA. All 13 species replaced their 12 rectrices simultaneously, with the onset of rectrix molt occurring in the early-middle stages of high-intensity primary molt. As expected, single-brooded early migrants molted earlier than double-brooded species whose nesting activities extend into late summer. However, our finding that late-molting species replaced their primaries more slowly and less intensively than early molting species was unexpected, as late-molting species are widely hypothesized to be under stronger migration-related time constraints. This surprising result appears to be at least partially explained by a positive association between the pace of molt and daylength; shorter late-summer days may mandate reduced daily food intake, lower molt intensity, and a slower pace of molt. In comparison to other passerines, flight feather molt in warblers of eastern North America is extraordinarily intense; at its peak, individuals are simultaneously replacing 50–67% of their 48 flight feathers (all 12 rectrices and 6–10 remiges on each wing) for 2–3 weeks or more. Because molt of this intensity is likely to present numerous challenges for flight, avoiding predators, foraging, and parental care, the period of flight feather molt for warblers constitutes a highly demanding phase of their annual cycle.
Ecological and evolutionary significance of molt in lowland Neotropical landbirds
Authors: Wolfe Jared D , Terrill Ryan S , Johnson Erik I , Powell Luke L , Brandt Ryder T 
Published: April 2021

AbstractThe slow-paced life history of many Neotropical birds (e.g., high survival and low fecundity) is hypothesized to increase lifetime fitness through investments in self-maintenance over reproduction relative to their temperate counterparts. Molt is a key investment in self-maintenance and is readily shaped by environmental conditions. As such, variation in molt strategies may be a key mechanism underlying life-history trade-offs and adaptation to new environments. Here, we review molt strategies from a diversity of lowland Neotropical landbirds and examine how variation in molt strategies, characterized by differences in molt insertions, timing, extent, and duration contribute to life-history variation and adaptation to diverse ecological conditions. In addition to our synthesis, we present a case study to examine the relationship between home range size and duration of the definitive prebasic molt of a well-studied subset of Amazonian landbirds. Our results suggest a connection between prolonged molt duration and larger home range size of small-to-medium-sized Amazonian landbirds. Our aims were to identify key gaps in our knowledge of Neotropical bird molt, to stimulate further comparative studies into the evolution of molt strategies, and to highlight how variation in molt strategies may be a key mechanism underlying life-history variation across latitudes.
Factors influencing care-seeking behaviour for mental illness in India: a situational analysis in Tamil Nadu
Authors: Jani Anant , Ravishankar Sindhu , Kumar Naresh , Vimitha J , Shah Soleil , Pari Anees , Ramasubramaniam C 
Published: April 2021

ABSTRACT

Background
The contribution of mental illness to the total burden of disease in India nearly doubled from 1990 to 2017, increasing from 2.5% of the total disability-adjusted life years in 1990 to 4.7% in 2017. Despite efforts by the Indian government, a treatment gap of 75–85%, with heterogeneity across multiple dimensions, exists across India. We conducted a qualitative study in Tamil Nadu, India, to better understand the contextual factors affecting the care-seeking behaviour for mental illness.

Methods
Qualitative methods, including semi-structured interviews and focus groups (FGs), were conducted with stakeholders involved in the mental health care pathway in Tamil Nadu. Ten semi-structured interviews and five FGs were conducted and analysed using an inductive approach to identify codes, using Dedoose v7, related to the emerging themes and categories.

Results
Our analyses identified three key areas that influence care-seeking: views on what causes and/or constitutes mental illness, stigma and discrimination associated with mental illness and broader factors influencing decision-making.

Conclusions
The specific contextual factors identified by our study can be used to design and implement approaches that can help to address some of the issues that influence the care-seeking behaviour and manifest in the treatment gaps seen in Tamil Nadu and in India, more generally.
Institutional Investors and Infrastructure Investing
Authors: Andonov Aleksandar , Kräussl Roman , Rauh Joshua 
Published: April 2021

AbstractInstitutional investors expect infrastructure to deliver long-term stable returns but gain exposure to infrastructure predominantly through finite-horizon closed private funds. The cash flows delivered by infrastructure funds display similar volatility and cyclicality as other private equity investments, and their performance similarly depends on quick deal exits. Despite weak risk-adjusted performance and failure to match the supposed characteristics of infrastructure assets, closed funds have received more commitments over time, particularly from public investors. Public institutional investors perform worse than private institutional investors. ESG preferences and regulations explain 25$\%$–40$\%$ of their increased allocation to infrastructure and 30$\%$ of their underperformance.
Flexor digitorum superficialis muscular activity is more reliable than mentalis muscular activity for rapid eye movement sleep without atonia quantification: A study of interrater reliability for artifact correction in the context of semiautomated scoring of rapid eye movement sleep without atonia
Authors: Cesari Matteo , Heidbreder Anna , Bergmann Melanie , Holzknecht Evi , Högl Birgit , Stefani Ambra 
Published: April 2021

Abstract

Study Objectives
To evaluate interrater reliability for artifact correction in the context of semiautomated quantification of rapid eye movement (REM) sleep without atonia (RWA) in the mentalis and flexor digitorum superficialis (FDS) muscles.

Methods
We included video-polysomnographies of 14 subjects with apnea–hypopnea index in REM sleep (AHIREM) &lt; 15/h and 11 subjects with AHIREM ≥ 15/h. Eight subjects had isolated REM sleep behavior disorder. A validated algorithm (www.osg.be) automatically scored phasic and “any” EMG activity in the mentalis muscle, and phasic EMG activity in the FDS muscles. Four independent expert scorers performed artifact correction according to the SINBAR (Sleep Innsbruck Barcelona) recommendations. Interrater reliability for artifact correction was computed with B-statistics. The variability across scorers of four RWA indices (phasic mentalis, “any” mentalis, phasic FDS and SINBAR—i.e. “any” mentalis and/or phasic FDS–EMG activity indices) was computed. With Friedman tests, we compared B-statistics obtained for mentalis and FDS muscles, and the variability of the RWA indices. Influence of AHIREM and REM sleep behavior disorder (RBD) diagnosis on the RWA indices variability was evaluated with linear regressions.

Results
Interrater reliability for artifact correction was higher in the FDS than in the mentalis muscle (p &lt; 0.001). Phasic FDS activity was minimally affected by artifacts. Accordingly, the phasic FDS EMG activity index had the lowest variability across scorers (p &lt; 0.001). Variability across scorers of the RWA indices including the mentalis muscle increased with AHIREM and was independent from RBD diagnosis.

Conclusions
Due to the consistently found low number of artifacts, phasic FDS activity is a reliable measure of RWA.
Wheat oral immunotherapy
Authors: Leeds Stephanie , Liu Elise G. , Nowak-Wegrzyn Anna 
Published: April 2021

Purpose of review
The prevalence of food allergy is increasing on a global scale, and therefore increased attention is being paid to specific food allergy epidemiology and management. There has been a large amount of progress made in the last decade on human trials of wheat oral immunotherapy (WOIT).

Recent findings
To date, there has been one multicenter, double-blind, randomized controlled trial of WOIT, one randomized, noncontrolled trial of WOIT, and several smaller, nonrandomized clinical trials of WOIT. WOIT trials are generally limited by smaller sample sizes, affecting the demographic skew of evaluated patients. In addition, there is minimal standardization of efficacy and safety outcomes between trial protocols, making head-to-head comparison challenging. However, some common themes emerge. The majority of WOIT regimens result in successful desensitization, and success is more likely with higher maintenance dosing for longer periods of time. Limited studies have looked at sustained unresponsiveness in WOIT. WOIT can induce allergic reactions, including anaphylaxis, but more severe reactions often have an associated augmenting factor, such as exercise. Lower maintenance doses likely are associated with less severe reactions, and food modification and/or adjunct therapeutics may also decrease the risk of reactions.

Summary
WOIT trials are ongoing and will optimize updosing protocols and maintenance doses to improve efficacy and safety.
Diagnosing Fractures of the Distal Tibial Articular Surface in Tibia Shaft Fractures: Is Computed Tomography Always Necessary?
Authors: Behlmer Richard J. , Simske Natasha M. , Graf Ryan M. , Kliethermes Stephanie A. , Lang Gerald J. , Whiting Paul S. 
Published: April 2021

Objectives:
To identify the incidence of distal articular fractures in a series of distal third tibia shaft fractures and to report the utility of both computed tomography (CT) scans and Radiographic Investigation of the Distal Extension of Fractures into the Articular Surface of the Tibia (RIDEFAST) ratios for identification of articular involvement.

Design:
Retrospective cohort.

Setting:
Level 1 trauma center.

Patients:
Four hundred seventeen patients with distal third tibia shaft fractures were included in the study.

Intervention:
Intramedullary nail or plate fixation.

Main Outcome Measures:
Type of articular fracture, time of diagnosis, and RIDEFAST ratios.

Results:
One hundred one of the 417 distal third fractures (24%) had a fracture of the distal tibia articular surface. Of these 101 fractures, 41 (41%) represented an extension of the primary fracture line and 60 (59%) were separate malleolar fractures. Of the 101 articular fractures, 95 (94%) were identified preoperatively and 6 (6%) were identified intraoperatively. Of the 95 fractures identified preoperatively, 87 (92%) were identified on plain radiographs and 8 (8%) by CT scan. Thirty-five preoperative CT scans were performed on distal third tibia shaft fractures in search of an intra-articular fracture. In 27 patients (77%), no articular fracture was present, representing an overall yield of 23% among CT scans performed to rule out an articular fracture in distal third tibia shaft fractures. RIDEFAST ratios for all 101 distal tibia shaft fractures with articular involvement and 100 fractures with no articular involvement were not significantly different (P > 0.05) using both coronal and sagittal plane measurements.

Conclusions:
CT scans performed on distal third tibia shaft fractures in search of articular fractures had a low yield (23%). Widespread use of CT scan to diagnose fractures of the distal tibia articular surface in the setting of distal tibia shaft fractures does not seem warranted. No statistically significant differences in RIDEFAST ratios were found between fractures with and without articular involvement, indicating that more work is necessary before RIDEFAST can be used to reliably rule out articular involvement in this setting.

Level of Evidence:
Diagnostic Level III. See Instructions for Authors for a complete description of levels of evidence.
Family history of esophageal cancer modifies the association of serum lipids and malignant esophageal lesions: a nested case-control study from the “Endoscopic Screening for Esophageal Cancer in China” trial
Authors: Wang Min-Min , Guo Chuan-Hai , Li Feng-Lei , Xu Rui-Ping , Liu Zhen , Pan Ya-Qi , Liu Fang-Fang , Liu Ying , Cai Hong , Liu Meng-Fei , He Zhong-Hu , Ke Yang 
Published: April 2021

Abstract

Background:
The association of lipids and cancer has varied greatly among different cancer types, lipid components and study populations. This study is aimed to investigate the association of serum lipids and the risk of malignant lesions in esophageal squamous epithelium.

Methods:
In the “Endoscopic Screening for Esophageal Cancer in China” (ESECC) trial, serum samples were collected and tested for total cholesterol (TC), triglycerides, low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol at the time of subject enrollment. Cases were defined as malignant esophageal lesions identified by baseline endoscopic examination or by follow-up to May 31, 2018. Controls were randomly selected using incidence density sampling in the same cohort. Conditional logistic models were applied to identify the association of serum lipids and the risk of malignant esophageal lesions. Effect modification was evaluated by testing interaction terms of the factor under assessment and these serum lipid indicators.

Results:
No consistent association between serum lipid levels and esophageal malignant lesions were found in a pooled analysis of 211 cases and 2101 controls. For individuals with a family history of esophageal cancer (EC), high TC, and LDL-C were associated with a significantly increased risk of having malignant lesions (odds ratio [OR]High vs. Low TC = 2.22, 95% confidence interval [CI]: 1.14–4.35; ORHigh vs. Low LDL-C = 1.93, 95% CI: 1.01–3.65). However, a negative association was observed in participants without an EC family history (ORHigh vs. Low TC = 0.69, 95% CI: 0.48–0.98, P
interaction = 0.002; ORHigh vs. Low LDL-C = 0.50, 95% CI: 0.34–0.76, P
interaction < 0.001).

Conclusions:
In this study, we found that the association of serum lipids and malignant esophageal lesions might be modified by EC family history. The stratified analysis would be crucial for population-based studies investigating the association of serum lipids and cancer. The mechanism by which a family history of EC modifies this association warrants further investigation.
Quantifying the Effect of Spectacle Frame Dimensions on Wind-Induced Ocular Plane Evaporation Using an in Vitro Model
Authors: Huynh Cassandra B. , Ngo William 
Published: April 2021

Purpose:
To quantify the effect of spectacle frame dimensions on wind-induced ocular plane evaporation.

Methods:
A drop of 0.5 μL water was pipetted onto an eye of a mannequin head. The face was fitted with a spectacle frame. A fan positioned 10 cm away directed air (185 CFM) toward the face and the time required for the drop to evaporate was recorded. This procedure was repeated with 31 different frames to obtain evaporation times for various eye sizes, vertical heights, vertex distances, temperature, and humidity. This was also repeated 30 times without spectacle wear to obtain evaporation times for various temperature and humidity conditions.

Results:
Spectacle wear increased evaporation times compared with nonspectacle wear, in both high (>35%) and low humidity (<30%) conditions (both P<0.01). Humidity was correlated with evaporation time, regardless of spectacle and nonspectacle wear (both P<0.01). Evaporation time did not correlate with spectacle eye size, vertical height, or vertex distance (all P≥0.21).

Conclusion:
This study showed that spectacle wear guarded against wind-induced evaporation at the ocular plane compared with nonspectacle wear. However, once spectacles were worn, eye size, vertical height, and vertex distance were not correlated with evaporation times. Humidity drove evaporation independent of spectacle wear.