bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANTIBACTERIAL EFFECTIVITY OF FLAVONOID FRACTION OF RAMANIA LEAF EXTRACT (Bouea macrophylla Griffith) AGAINST Porphyromonas gingivalis
Authors: Qomariyah Lailatul , Panjaitan Fransiska Uli Arta , Adhani Rosihan 
Published: November 2021

Background: Chronic periodontitis is a periodontal disease with 80% of all cases of periodontitis. The major causes are the accumulation of plaque and bacteria. The dominant bacteria in chronic periodontitis is Porphyromonas gingivalis. Treatment of chronic periodontitis can be done by scaling and root planing and supporting therapy by using mouthwash such as Chlorhexidine gluconate 0.2% which is the gold standard in the treatment of periodontal disease. Chlorhexidine gluconate 0.2% has disadvantages so that nowadays research on herbal plants is being done to find alternative medicines that are more effective. Ramania (Bouea machropylla Griffith) leaf contains flavonoids that have antibacterial properties. Objective: To analyze the antibacterial effectivity of the flavonoid fraction of Ramania leaf extract against Porphyromonas gingivalis that causes chronic periodontitis. Method: True experimental study and post-test with control group design consisting of 5 treatment groups, namely flavonoid fraction of ramania leaf extract with concentrations of 0.1%, 0.3%, and 0.5%, chlorhexidine gluconate 0.2% as a control positive and aquadest as a negative control. Each group was repeated 6 times. Antibacterial tests using the dilution method with inhibitory rates calculated using a UV-Vis spectrophotometer and killing rates were calculated using a Colony Counter. Results: The average difference in absorbance values obtained inhibitory rates at concentrations of 0.1%, 0.3%, and 0.5%. One Way Anova Test showed a significance value of 0,000 (p < 0.05). The average number of colonies after 24 hours incubation showed the results of a kill rates in the concentration group of 0.3%, 0.5%, and positive control. The Kruskal Wallis test showed a significance value of 0,000 (p < 0.05). Conclusion: The minimum inhibitory concentration (MIC) was obtained at a concentration of 0.1% and the minimum bactericidal concentration (MBC) was obtained at 0.3% concentration. Keywords: Flavonoid Fraction, MIC, MBC, Porphyromonas Gingivalis, Ramania Leaf Extract.
THE COMPARISON OF RAMANIA (Bouea macrophylla Griff) AND BINJAI (Mangifera caesia) LEAVES EXTRACT GEL EFFECT ON COLLAGEN DENSITY
Authors: Nabilah Nabilah , Taufiqurrahman Irham , Rasyid Nolista Indah 
Published: November 2021

Background: The extract of ramania Bouea macrophylla Griff) and binjai (Mangifera caesia) leaf have flavonoid compounds that function as antioxidants to balance the amount of Reactive Oxygen Species (ROS) in tissues and optimize wound healing by helping synthesis of hydroxyproline which is used as a collagen synthesis material. Objective: To compare the effect of 15% concentration of ramania leaf extract gel, 15% concentration of binjai leaf extract gel on collagen density in back incision wounds of male Wistar rats on day 7 and day 14. Methods: This study used a true experimental design with a posttest-only with control group design. The study sample used male wistar rats that were healthy and active, aged 2-3 months with a body weight of 250-300 grams. The total sample was 18 rats divided into 6 groups. The 15% concentration of ramania and binjai leaves was given topically, then the rats were euthanized on the 7th and 14th day. Collagen index measurement was using hydroxyproline concentration. Results: Two-way Anova data analysis showed a significant value of 0.00 (p<0.05), which means that there was a difference in effect between the treatment gel and wound day. Bonferroni Post Hoc test showed a significant value in all treatment gel groups. Conclusion: There is a difference in the effect of 15% concentration of ramania leaf extract gel and 15% concentration of binjai extract gel on collagen density. Binjai leaf extract gel at 15% concentration is more effective for collagen density than Ramania leaf extract at 15% concentration and placebo. Keywords : Binjai Leaf Extract Gel, Collagen, Hydroxyproline, Ramania Leaf Extract Gel.
EFFECT OF CHANNA MICROPELTES IN THE GRANULATION, FIBROSIS AND NECROSIS OF DIABETIC WOUND HEALING
Authors: Carabelly Amy Nindia , Putri Utami Juliyatin , Aspriyanto Didit , Reksi Muhammad Hasanu , Puspitasari Dewi , Rachmadi Priyawan 
Published: November 2021

Background: Diabetes mellitus (DM) is characterized by persistent hyperglycemia. The symptoms of DM is delayed wound healing. Delayed wound healing in diabetes will increase the risk of wound complications that will hinder the healing process, and lead to complications such as fibrosis and necrosis. The use of Channa Micropeltes (CM) extract at a dose of 16 mL/kg BW orally is proven to general optimal wound closure and wound contraction clinically in Wistar rats as diabetic model on day 14.However, the histopathological description of wound healing is yet to be known. Objective: To analyze the effect of 16 mL/kg BW dose of CM extract on histopathological changes of wound healing granulation tissue, fibrosis and necrosis in diabetic Wistar rats on day 14. Materials and Methods: This study was a true experimental design with a post-test only control group design. The samples were divided into two groups, namely the diabetic model group given CM extract at 16 mL/kg BW dose for 14 days, and the diabetic model group given BR2 feed only for 14 days. Results: The results of Mann-Whitney U test showed p = 0.003 for granulation tissue, p = 0.411 for fibrosis and p = 1 for necrosis, with the level of significance was p<0.05. Conclusion: The CM extract at 16 mL/kg BW dose affects the histopathological description of granulation tissue which presents a better result than those in the control group but did not affect the features of fibrosis and necrosis in diabetic Wistar rats on day 14. Keywords: Channa Micropeltes, Diabetic wound, Fibrosis, Granulation tissue, Necrosis.
RISK FACTORS OF ANGULAR CHEILITIS AT GUSTI HASAN AMAN DENTAL HOSPITAL SOUTH KALIMANTAN
Authors: Azizah Aulia , Pramitha Selviana Rizky , Apriasari Maharani Laillyza 
Published: November 2021

Background: The second highest burden of all diseases in world population includes infectious disease with a total of 28% cases. Angular cheilitis is an infectious condition on the corner of the mouth that may initiate masticatory, facial expression and speech dysfunction due to the involvement of orbicularis oris muscle surrounding the lips. The management of angular cheilitis comprises the elimination of causative microbes using antifungal agent. Therapeutic failure reveals the disregard of any related risk factor. Purpose: To analyze the risk factors of angular cheilitis in Gusti Hasan Aman Dental Hospital year 2019. Method: This study resorted analytical descriptive design of quantitative approach using cross-sectional method. Samples were 65 dental statuses of patients in Oral Medicine Clinic of Gusti Hasan Aman Dental Hospital year 2019. Result: Univariate data analysis presented the distribution of children category aged ≤ 18 years old (75.8%), men (54.8%), not consuming vegetable and fruit behaviour (46.8%), duration of treatment 1-7 days (56.4%), and incidence of angular cheilitis (75.8%). Fisher exact test unveiled the relationship between age and angular cheilitis (p<0.05) in which age ≤ 18 years old was 4.266 fold higher to experience angular cheilitis, while the relationship between gender and angular cheilitis (p<0.05) demonstrates the predilection of male with 4.853 fold at risk than female. Conclusion: Age and gender are risk factors in the incidence of angular cheilitis at Gusti Hasan Aman Dental Hospital year 2019. Keywords : Age, Angular Cheilitis, Behavior, Gender
REHABILITATION OF MASTICATION AND LACK OF SPACE TREATMENT IN NARROW EDENTULOUS WITH FIXED-FIXED BRIDGE
Authors: Arifin Rahmad , Pertiwi Fitriana Caessar 
Published: November 2021

Background: Loss of posterior teeth can lead to disharmony in the curvature of the jaw. Antagonistic teeth and surrounding teeth will migrate to the edentulous causing reduced mastication function and TMJ disturbance. Several cases of narrow edentulous occurred due to tooth shifting caused by edentulous that was left empty for a long period. Creating a fixed-fixed bridge is aimed to restore the aesthetics, function, and comfort for patients which caused by the missing teeth. Fixed-fixed bridge consist of a retainer that function as a support to the abutment; a pontic that function to replace the missing tooth; and a connector that function to connect the pontic and the retainer. A narrow space for pontics can disrupt the aesthetic and functional aspects. Case Report: A 24 year-old male patient was referred to Prosthodontic Clinic, Gusti Hasan Aman Dental Hospital with a complain of pain on the jaw joint and missing of left lower molar for about 5 years. Patient always masticate on one side after the left lower molar was missing. Extraoral examination found the patient to be in good condition, no enlargement of major salivary glands, the vital signs were good, but upon TMJ examination there was clicking sounds on the left side. Intraoral examination showed space narrowing resulted from mesial and distal drifting of 37 and 35 but not significant, therefore it was still possible to perform rehabilitation using fixed-fixed bridge with abutments on 37 and 35 with modification of pontic shape for 36 to resemble a premolar tooth with occlusal surface resembling a molar tooth. Treatment planning for fixed prosthetic using fixed-fixed bridge with porcelain fused to metal material on 35, 36, and 37 with ridge lap pontic type modification Conclusions: Treatment was successful to provide enough space for the pontic by modification of the shape and the size of the pontic. Keywords: Fixed-fixed bridge. lack of space, mastication.
ODONTECTOMY MANAGEMENT WITH LOCAL ANESTHESIA IN PATIENT WITH OPEN-ANGLE GLAUCOMA
Authors: Sejati Bramasto Purbo , Dwiraharjo Bambang , Astuti Elizabeth Riyati Titi 
Published: November 2021

Background: Glaucoma is characterized by optic neuropathy with increased intraocular pressure. The high prevalence of impaction causes some glaucoma patients to require odontectomy. There are no contraindications to odontectomy in glaucoma patients, but special preparation is needed to prevent recurrence during the procedure. Glaucoma recurrence is precipitated by increased intraocular pressure which correlates with elevated systemic blood pressure with increased intraocular pressure and corticosteroid use. Therefore, dentists must be vigilant in choosing an atraumatic odontectomy procedure, anesthetic dose and techniques, as well as administering the type and dose of analgesics. Objective: This paper reports a case of mandibular third molar odontectomy with local anesthesia in a patient with open-angle glaucoma, which is a rare case and in this case there is a high risk of complications. Case: A 26-year-old male patient complained of pain in the left back gum when chewing. Orthopantomographic radiographic examination showed impacted 38. The patient has been diagnosed with open-angle glaucoma for 5 years. An odontectomy was performed under local anesthesia. Durante surgery, bleeding is minimal and does not cause recurrence of glaucoma. Postoperative evaluation gave good results, minimal complications, and no recurrence of glaucoma.Conclusion: Odontontectomy with local anesthesia in glaucoma patients requires special preparation in the form of atraumatic surgical procedures and perioperative pharmacotherapy management in the form of pre-emptive analgesia, selection of a maximum of two ampoules of lidocaine and epinephrine 1:80,000 with the mandibular block anesthetic technique, and using multimodal analgesia in combination with NSAIDs without corticosteroids. Keywords: Complications, Glaucoma, Odontectomy
COMPARISON OF APICAL LEAKAGE VALUE BETWEEN EUCALYPTOL AND ORANGE OIL AS GUTTA PERCA SOLVENT
Authors: Diana Sherli , Yuliati Rizki Sri , Sukmana Bayu Indra 
Published: November 2021

Background: The success or failure of root canal treatment is influenced by anatomical factors of the root canal, bacterial infection that causes inadequate hygiene, formation and filling of root canals, iatrogenic factors and several other factors. The average success of root canal treatment is 86-95%, while the failure of canal treatment ranges from 5-14%. Root canal re-treatment can be performed in the event of failure of root canal treatment. The method that can be used is gutta percha solvent. The gutta percha solvents used were Chloroform, Eucalyptol, Orange Oil, and Xylene, but chloroform has been categorized as a carcinogenic substance. Guta percha solvent can cause the intercrystalline distance to be larger, so that it can damage the apical density at obturation. This can create a gap between the gutta percha and the sealer which can cause apical leakage. Objective: To compare the value of apical leakage after root canal re-treatment between gutta percha solvent eucalyptol and orange oil. Method: The research method used is True Experimental with post-test only with control group design. A minimum sample of 8 teeth in a group. Total samples from all groups were 24 teeth. The teeth were stained using methylene blue and measured using stereomycroscopes. Results: the highest mean apical leakage was eucalyptol (4.55±2.59), xylene (2.77±1.94), and the lowest was citrus oil (2.20 ±1.06). The results of One-Way ANOVA test showed that there were no significant differences between orange oil, eucalyptol, and xylene (positive control). Conclusion: Eucalyptol has a higher average apical leakage value compared to orange oil and Xylene after root canal re-treatment as a gutta percha solvent. There was no significant difference between orange oil, Eucalyptol, and Xylene.Keywords: Apical leakage, eucalyptol, orange oil
THE EFFECTIVENESS OF COMPOMER AND GIC AGAINST PREVENTION IN ENAMEL DEMINERALIZATION
Authors: Arifin Fadil Abdillah , Puspitasari Yustisia , Hasanuddin Nur Rahmah , Wijaya M. Fajrin , Aldilawaty Sari 
Published: November 2021

Background: Several studies showed that fluoride interferes in the dynamics involved in the development of caries and could present an antimicrobial effect or provide demineralization inhibition or dental remineralization. The development of fluoride-releasing materials can contribute to a preventive of demineralization. GIC and Compomer are restorative materials containing fluoride which can prevent demineralization. Purpose: To analyze the effectiveness of Compomer and GIC against prevention in enamel demineralization. Method: The cavities were made on 18 bovine teeth which grouped into 3 groups, each group consisting of 6 bovine teeth. After the restorative procedures, the teeth were submitted to demineralization and remineralization cycling during 14 days. The sections of the teeth were examined under scanning electron microscope after undergoing pH cycling. The data were analyzed using the Kruskal-Wallis and Tukey Test (p<0.05). Results: GIC group showed the lowest lesion depth of demineralization (10.9883 ± 0.74333) followed by Compomer group (25.4183 ± 3.44268) and Control group (88.9783 ± 3.02495). Conclusion: GIC restorative materials have a better enamel demineralization prevention effect than Compomer. Keywords: compomer, demineralization, fluoride, GIC, remineralization
Notes on the genus Ardisia (Primulaceae) in Thailand and Peninsular Malaysia
Authors:   Department of Biology Education, Khairun University, Ternate, North Maluku 97719. Indonesia, Suparman Suparman , Pornpongrungrueng Pimwadee ,   Applied Taxonomic Research Center (ATRC), Department of Biology, Faculty of Science, Khon Kaen University, Khon Kaen   40002, Thailand, Chantaranothai Pranom ,   Applied Taxonomic Research Center (ATRC), Department of Biology, Faculty of Science, Khon Kaen University, Khon Kaen   40002, Thailand
Published: November 2021

The lectotype for Ardisia kerrii is designated here. Ardisia cordulata var. appresso-hirsuta is placed as a new synonym of A. demissa. Additionally, the correct locations of four species that were misinterpreted are also given. Now A. betongensis is excluded from the list of Thai Ardisia.
Design and Implementation of Efficient Transmission of Cloud Data in Wireless Media
Authors: Nikam Virendra Pandharipant , Dhande Sheetal S 
Published: November 2021

Nowadays, information security is a challenge especially when transmitted or shared in public clouds. Many of
researchers have been proposed technique which fails to provide
data integrity, security, authentication and another issue related
to sensitivity data. The most common techniques were used to
protect data during transmission on public cloud are cryptography,
steganography, and compression. The proposed scheme suggests an
entirely new approach for data security on public cloud. Authors
have suggested an entirely new approach that completely makes
secret data invisible behind carrier object and it is not been detected
with the image performance parameters like PSNR, MSE, entropy
and others. The details of results are explain in result section of
paper. Proposed technique have better outcome than any other
existing technique as a security mechanism on a public cloud.
Primary focus of suggested approach is to minimize integrity loss
of public storage data due to unrestricted access rights by uses. To
improve reusability of carrier even after data concealed is really a
challenging task and achieved through suggested approach.
The Effect of Leukocyte Concentration on Platelet-Rich Plasma Injections for Knee Osteoarthritis
Authors: Abbas Aazad , Du Jin Tong , Dhotar Herman S. 
Published: November 2021

Background:It is hypothesized that leukocyte-poor (LP) platelet-rich plasma (PRP) is preferred over leukocyte-rich (LR) PRP for the treatment of knee osteoarthritis (OA).Methods:The MEDLINE, Embase, and Cochrane databases were reviewed for all English-language studies comparing LP-PRP or LR-PRP with relevant controls or each other. The follow-up periods were 6 months and 12 months. The primary outcome measure was the change in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) score between baseline and follow-up. The secondary outcome measures were changes in the WOMAC pain subscale, visual analog scale (VAS) for pain, and International Knee Documentation Committee (IKDC) subjective score between baseline and follow-up, and the incidence of local adverse reactions. Treatment outcomes were analyzed using the mean difference between treatments for continuous outcomes and the odds ratio for binary outcomes, with 95% credibility intervals. Treatment modalities were ranked using the surface under the cumulative ranking (SUCRA) probabilities. Risk of bias was assessed using the relevant Cochrane tools, RoB 2 (version 2 of the Cochrane risk-of-bias tools) for randomized controlled trials (RCTs) and ROBINS-I (Risk of Bias in Non-Randomized Studies – of Interventions) for prospective comparative studies (PCSs).Results:This network meta-analysis included 23 studies: 20 RCTs and 3 PCSs, with a total of 2,260 patients and a mean follow-up period of 9.9 months. The overall risk-of-bias assessment of the RCTs revealed that 9 studies had low risk, 7 had some concerns, and 4 had high risk. The overall risk-of-bias assessment of the PCSs revealed that 1 study had low risk and 2 had moderate risk. We found no significant (p < 0.05) difference in all outcome measures and local adverse reactions between LP-PRP and LR-PRP. SUCRA rankings revealed that, for all outcome measures, LP-PRP is preferred to LR-PRP across follow-up periods.Conclusions:Leukocyte concentration of PRP does not play a significant role in patient-reported outcome measures for knee OA. LP-PRP is preferred to LR-PRP according to SUCRA rankings, but this preference may not be important in clinical practice.Level of Evidence:TherapeuticLevel II. See Instructions for Authors for a complete description of levels of evidence.
ANÁLISE SENSORIAL
Authors: Lara Jose Edson , Vilela Marcela Augusta Nogueira , Ribeiro Rodrigo Medeiros , Tissot-Lara Thalles Augusto , Silva Altieres de Oliveira 
Published: November 2021

Esta pesquisa estuda a convergência perceptiva dos consumidores na compra de perfumes, considerando-se os quatro sentidos (olfato, visão, tato e audição (influências sociais)). A convergência perceptiva foi determinada como variável dependente, e cada sentido, uma variável independente. Realizou-se um levantamento com 321 respondentes, evidenciando a influência dos construtos sensoriais do consumidor. As correlações mais fortes foram entre "percepção olfativa" e "audição" (imagem social do perfume) e "cheiro" e "toque". As menores correlações foram "visão" e "cheiro". A convergência sensorial é melhor explicada pelos construtos "cheiro" e "toque", enquanto a "visão" e a "audição" (sugestões de perfume), não indicaram fortes contribuições. Constatou-se a importância da análise de convergência sensorial no setor de perfumaria, tanto em investigações científicas quanto na indústria. Recomenda-se a utilização de neurotecnologias para se obter conhecimento sobre influências neurossensoriais, por exemplo a neuroplasticidade, nas experiências sensoriais em perfumes, produtos alimentícios, bebidas, fármacos, varejo, entre outras possibilidades de marketing.
Best Practices for Managing Subsea Well Plug and Abandonment Operation in Offshore Malaysia During COVID-19 Pandemic
Authors: Utta Arie Muchalis , Barat Junnyaruin Anak , Maluan Lilihani Binti , Omar Mohd Zulkifli Bin , Yahaya Fadzil Bin , Nasron Budi Mawardi Bin 
Published: November 2021

Abstract
In 2020, PCSB implemented the first permanent Plug & Abandonment (P&A) campaign for three Subsea wells in a gas field offshore Malaysia. The main objective of the campaign was to establish two (2) barriers for every movable hydrocarbon or overpressure bearing sand by placing laterally extended cement plug across impermeable formation with enough formation strength to handle the pressure of the formation to be isolated. The unique case of this operation was the challenges to execute PCSB's first subsea P&A operation in gas field Malaysia during pandemic situation. In March 2020, the Malaysian government imposed Movement Control Order (MCO) to curb the spread of the COVID-19. A semi-submersible rig was on-hired a week after government initiated the MCO, resulted in the rig preparation being badly hampered due to manpower management and material fabrication and delivery. PCSB was exposed to expensive rig daily rate that had to be managed. Four (4) main challenges were encountered during operation: safe protection for workers, expensive standby cost, manpower management and material fabrication and delivery. This paper, from the ‘project management’ point of view, describes the journey of managing rig operation during PCSB's first subsea wells P&A in Malaysia efficiently amidst the pandemic by reducing the impact of COVID-19 on project cost. With the experience of managing rig for subsea well operation, a complex operation in Malaysia, amidst pandemic, PCSB sharing on the experience is beneficial to provide context setting and benchmark on maintaining the efficiency of operation. Wells successfully met the objective of operation with no incident occurred, negotiated reduction on standby cost and managed to bring critical manpower on time during operation.