bluuebunny/crossref_metadata_2025_split huggingface dataset:
PEMBELAJARAN INOVATIF BERBASIS MEDIA PENDIDIKAN
Authors: Irawan Irawan 
Published: March 2021

ABSTARAK IRAWAN: PEMBELAJARAN INOVATIF BERBASIS MEDIA PENDIDIKAN, Inovasi Pendidikan adalah suatu ide, barang, metode yang dirasakan sebagai hal yang baru bagi seseorang atau sekelompok orang sebagai hasil inovation/discovery. Inovasi diadakan untuk mencapai tujuan tertentu atau untuk memecahkan masalah tertentu. Kemampuan guru dalam melaksanakan poses belajar mengajar sangat bepengaruh terhadap tingkat pemahaman siswa. Biasanya guru menggunakan model pembelajaran konvensional dan metode ceramah sebagai cara untuk menyampaikan materi pelajaran. Dari pelaksanaan pembelajaran-pembelajaran yang inovatif terjadi peningkatan motivasi belajar siswa, misalnya siswa akan lebih tertarik dan tertantang untuk menerima atau mengikuti pelajaran, respon siswa meningkat, dan siswa juga lebih aktif dan kreatif. Dalam proses pembelajaran siswa akan cenderung aktif bertanya serta aktif menyelesaikan suatu permasalahan dalam matematika. Media pembelajaran merupakan segala sesuatu yang dapat menyalurkan informasi dari sumber informasi kepada penerima informasi. Istilah media ini sangat populer dalam bidang komunikasi. Proses belajar mengajar pada dasamya juga merupakan proses komunikasi, sehingga media yang digunakan dalam pembelajaran disebut media pembelajaran.
MAJELIS TAKLIM KELILING DALAM MEMBINA SIKAP KEAGAMAAN MASYARAKAT
Authors: Irawan Irawan , Nasrudin Nasrudin , Hermawan Denny 
Published: March 2021

AbstarctMajelis taklim is one of the non-formal diniyah educational institutions which aims to increase the faith and piety of Allah SWT and noble morals for its worshipers, as well as manifesting mercy for the universe. In practice, majelis taklim is the most flexible teaching place or Islamic education that is not bound by time. This study aims to reveal data about the role of the Taklim Council in fostering religious attitudes of the community and reveal the inhibiting and supporting factors of the taklim assembly in increasing the practice of community worship. Data collection techniques using questionnaire distribution techniques to the congregation taklim assemblers and observations made to look directly at the reality of the assembly and the objective conditions of the taklim assembly. After the data is collected, the next step is data processing and analysis. For the observational data, logical interpretation is used. The questionnaire result data is used in the percentage scale. The results showed that, the role of the taklim assembly had a low relationship. This can be seen from the correlation coefficient between the variables x and y obtained a correlation value of 0.16 from respondents numbering 40. This means that if interpreted is a very low correlation because it is in the interval 0.00-0.199. Thus proving that the existence of majlis taklim is able to provide religious guidance for the community in improving worship and character of the community with a good attitude category. AbstarkMajelis taklim adalah salah satu lembaga pendidikan diniyah non formal yang bertujuan meningkatkan keimanan dan ketakwaan kepada Allah SWT dan akhlak mulia bagi jamaahnya, serta mewujudkan rahmat bagi alam semesta. Dalam prakteknya, majelis taklim merupakan tempat pengajaran atau pendidikan agama Islam yang paling fleksibel dan tidak terikat oleh waktu. Penelitian ini bertujuan untuk mengungkapkan data tentang peran Majelis taklim dalam membina sikap keagamaam masyarakat dan mengungkap faktor penghambat dan pendukung majelis taklim dalam meningkatkan pengamalan ibadah masyarakat. Teknik pengumpulan data menggunakan teknik penyebaran angket kepada jamaah majelis taklim dan observasi dilakukan untuk melihat langsung terhadap realitas majelis dan kondisi obyektif majelis taklim. Setelah data terkumpul, langkah selanjutnya diadakan pengolahan dan analisa data. Untuk data hasil observasi digunakan penafsiran logika., data hasil angket digunakan skala prosentasi. Hasil penelitian menunjukan bahwa, peranan majelis taklim mempunyai hubungan yang rendah. Hal ini terlihat dari Koefisien korelasi antara variabel x dan y diperoleh nilai korelasi sebesar 0,16 dari responden yang berjumlah 40. Hal ini berarti jika diinterpretasikan merupakan korelasi yang sangat rendah karena berada pada interval 0,00-0,199. Sehingga membuktikan bahwa keberadaan majlis taklim mampu memberikan bimbingan keagamaan bagi masyarakat dalam meningkatkan ibadah dan akhlak masyarakat dengan kategori sikap yang baik.
IMPLEMENTASI KEBIJAKAN ABSEN ELEKTRONIK (E-ABSENSI BNI INNOVATION) BERPENGARUH TERHADAP KINERJA PEGAWAI PADA DIVISI JAKARTA COLLECTIONMANAGEMENT PADA PT. BANK NEGARA INDONESIA 1946 (PERSERO) Tbk, JAKARTA-BARAT
Authors: Kurniawan Irvan Arif , . Hilman , Lestari Indri 
Published: March 2021

This journal entitled Implementation of Electronic Absence Policy (BNI E-Attendance Innovation) Affects Employee Performance in the Jakarta Division of Collection Management at PT. Bank Negara Indonesia 1946 (Persero) Tbk, West Jakarta ”. The population in this study are employees who work at PT. Bank Negara Indonesia 1946 (persero) Tbk, West Jakarta, which measured 222 people, from which the researcher used 69 people as samples to be tested. The research method used in this research is the associative method, the data technique used is literature study and field study through observation and questionnaires. Furthermore, it is tested by quantitative analysis using a proportional stratified random sampling technique, and data processing using the SPSS (Product and Solution Service) program. Keyword: Implementation, E-Attendance, the performance
Ancaman, Serangan dan Tindakan Perlindungan pada Keamanan Jaringan atau Sistem Informasi : Systematic Review
Authors: Bustami Agustani , Bahri Syamsul 
Published: March 2021

Keamanan jaringan atau sistem informasi sangat berdampak dengan kehadiran berbagai ancaman atau serangan yang dapat menyebabkan kebocoran informasi sensitif dan rahasia serta penurunan kinerja organisasi. Terdapat beraneka ragam ancaman atau serangan pada keamanan jaringan atau sistem informasi seperti insider attacks, eavesdropping, masquerading, man-in-the-middle-attack, virus attack atau denial of service attack dan lain sebagainya. Teknologi keamanan yang sesuai dapat ditetapkan sebagai antisipasi dan perlindungan dari beragam ancaman atau serangan keamanan. Agar penentuan teknologi keamanan dapat sesuai dengan kebutuhan organisasi, maka diperlukan pemetaan terlebih dahulu antara jenis ancaman atau serangan dengan teknologi keamanan yang ada berdasarkan kepada aspek keamanan, yaitu: kerahasiaan (confidentiality), integritas (integrity) dan ketersediaan (availability) [1][2]. Firewall, IDS, antivirus system dan cryptographic system menjadi teknologi keamanan pilihan disebabkan kehandalan mereka dalam mengantisipasi dan melindungi jaringan atau sistem informasi pada aspek keamanan yang berbeda-beda
Pengukuran Waktu Baku Perakitan Pena Dengan Menggunakan Waktu Jam Henti Saat Praktikum Analisa Perancangan Kerja
Authors: Rahayu Monita , Juhara Sutresna 
Published: March 2021

Penelitian ini bertujuan untuk mengetahui waktu baku perakitan pena saat melakukan praktikum Analisa Perancangan Kerja khususnya untuk modul time study yang selanjutnya akan digunakan untuk membuat rancangan alokasi penggunaan waktu saat praktikum yang akan datang. Penelitian ini dilakukan pada mahasiswa Program Studi Teknik Industri, Fakultas Teknik, Universitas Islam Syekh-Yusuf yang sedang melakukan praktikum. Metode yang digunakan adalah metode jam henti (stopwatch), metode ini dilakukan dengan mengukur waktu melalui pengamatan dan mencatat waktu-waktu kerja untuk setiap siklus dengan menggunakan alat-alat yang telah disiapkan yang selanjutnya data waktu ini dihitung waktu baku. Waktu baku adalah waktu yang dibutuhkan untuk mengerjakan atau menyelesaikan suatu aktivitas atau pekerjaan oleh tenaga kerja yang wajar pada situasi dan kondisi yang normal. Jumlah penelitian pendahuluan sebanyak 25 kali yang diambil dari lima orang mahasiswa yang dijadikan operator. Operator yang dipilih dilatih terlebih dahulu sebelum melakukan perakitan pena.. Faktor penyesuaian menggunakan cara westinghouse. Hasil penelitian diperoleh semua rata-rata subgrup berada pada batas kendali yang normal selain itu kinerja dari operator stabil, opetator bekerja normal bahkan bisa dikategorikan bekerja cepat.Kata kunci: pengukuran waktu jam henti, waktu baku, faktor penyesuaian
Balance Impairments as Differential Markers of Dementia Disease Subtype
Authors: Mc Ardle Ríona , Pratt Stephanie , Buckley Christopher , Del Din Silvia , Galna Brook , Thomas Alan , Rochester Lynn , Alcock Lisa 
Published: March 2021

BackgroundAccurately differentiating dementia subtypes, such as Alzheimer’s disease (AD) and Lewy body disease [including dementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD)] is important to ensure appropriate management and treatment of the disease. Similarities in clinical presentation create difficulties for differential diagnosis. Simple supportive markers, such as balance assessments, may be useful to the diagnostic toolkit. This study aimed to identify differences in balance impairments between different dementia disease subtypes and normal aging using a single triaxial accelerometer.MethodsNinety-seven participants were recruited, forming four groups: cognitive impairment due to Alzheimer’s disease (AD group; n = 31), dementia with Lewy bodies (DLB group; n = 26), Parkinson’s disease dementia (PDD group; n = 13), and normal aging controls (n = 27). Participants were asked to stand still for 2 minutes in a standardized position with their eyes open while wearing a single triaxial accelerometer on their lower back. Seven balance characteristics were derived, including jerk (combined, mediolateral, and anterior–posterior), root mean square (RMS; combined, mediolateral, and anterior–posterior), and ellipsis. Mann–Whitney U tests identified the balance differences between groups. Receiver operating characteristics and area under the curve (AUC) determined the overall accuracy of the selected balance characteristics.ResultsThe PDD group demonstrated higher RMS [combined (p = 0.001), mediolateral (p = 0.005), and anterior–posterior (p = 0.001)] and ellipsis scores (p &lt; 0.002) than the AD group (AUC = 0.71–0.82). The PDD group also demonstrated significantly impaired balance across all characteristics (p ≤ 0.001) compared to the controls (AUC = 0.79–0.83). Balance differences were not significant between PDD and DLB (AUC = 0.69–0.74), DLB and AD (AUC = 0.50–0.65), DLB and controls (AUC = 0.62–0.68), or AD and controls (AUC = 0.55–0.67) following Bonferroni correction.DiscussionAlthough feasible and quick to conduct, key findings suggest that an accelerometer-based balance during quiet standing does not differentiate dementia disease subtypes accurately. Assessments that challenge balance more, such as gait or standing with eyes closed, may prove more effective to support differential diagnosis.
Telomere Length in Valve Tissue Is Shorter in Individuals With Aortic Stenosis and in Calcified Valve Areas
Authors: Saraieva Ilona , Benetos Athanase , Labat Carlos , Franco-Cereceda Anders , Bäck Magnus , Toupance Simon 
Published: March 2021

BackgroundShort telomere length (TL) is associated with age-related diseases, in particular cardiovascular diseases. However, whether the onset and course of aortic stenosis (AS) is linked to TL in aortic valves remains unknown.ObjectivesTo assess telomere dynamics (TL and telomerase activity) in aortic valves and the possible implication of TL in onset and course of AS.MethodsDNA was extracted from aortic valves obtained from 55 patients (78.2% men; age, 37–79 years), who had undergone replacement surgery due to AS (AS group, n = 32), aortic valve regurgitation and aortic dilation (Non-AS group, n = 23). TL was measured by telomere restriction fragment analysis (TRF) in calcified and non-calcified aortic valve areas. Telomerase activity was evaluated using telomerase repeat amplification protocol (TRAP) in protein extracts from non-calcified and calcified areas of valves obtained from 4 additional patients (50% men; age, 27–70 years).ResultsTL was shorter in calcified aortic valve areas in comparison to non-calcified areas (n = 31, 8.58 ± 0.73 kb vs. 8.12 ± 0.75 kb, p &lt; 0.0001), whereas telomerase activity was not detected in any of those areas. Moreover, patients from AS group displayed shorter telomeres in non-calcified areas than those from the Non-AS group (8.40 ± 0.64 kb vs. 8.85 ± 0.65, p = 0.01).ConclusionsShort telomeres in aortic valves may participate in the development of AS, while concurrently the calcification process seems to promote further local decrease of TL in calcified areas of valves.
Assessing L. donovani Skin Parasite Load: A Proof of Concept Study of a Microbiopsy Device in an Indian Setting
Authors: Cloots Kristien , Singh Om Prakash , Singh Abhishek Kumar , Van der Auwera Gert , Kumar Prashant , Gedda Mallikarjuna Rao , Rai Tulika Kumari , Hasker Epco , Sundar Shyam , Boelaert Marleen 
Published: March 2021

BackgroundIn the endgame of the elimination initiative of visceral leishmaniasis (VL) on the Indian subcontinent, one of the main questions remaining is whether asymptomatically infected individuals also contribute to transmission. We piloted a minimally invasive microbiopsy device that could help answer this question. While the potential of this device has been previously illustrated in Ethiopia, no such information is available for the setting of the Indian subcontinent. In this proof of concept study we aimed to assess 1) to what extent skin parasite load obtained with the new microbiopsy device correlates with disease status, 2) to what extent skin parasite load correlates with blood parasite load in the same subject, and 3) to what extent the skin parasite load obtained from different sampling sites on the body correlates with one another.MethodsWe performed a pilot study in Bihar, India, including 29 VL patients, 28 PKDL patients, 94 asymptomatically infected individuals, 22 endemic controls (EC), and 28 non-endemic controls (NEC). Presence of infection with L. donovani in the blood was assessed using Direct Agglutination Test, rK39 ELISA, Whole Blood Analysis measuring IFN-γ and qPCR. A skin sample was collected with the microbiopsy device on two different locations on the body. PKDL patients provided a third skin sample from the edge of a PKDL lesion. Parasite load in the skin was measured by qPCR.FindingsWe found a clear correlation between the skin parasite load obtained with the microbiopsy device and disease status, with both higher skin parasite loads and higher proportions of positive skin samples in VL and PKDL patients compared to asymptomatics, EC, and NEC. No clear correlation between skin parasite load and blood parasite load was found, but a moderate correlation was present between the skin parasite load in arm and neck samples. In addition, we found four positive skin samples among asymptomatic individuals, and 85% of PKDL lesions tested positive using this microbiopsy device.ConclusionsIn line with previous pilot studies, our results from an Indian setting suggest that the microbiopsy device provides a promising tool to measure skin parasite load, and – if validated by xenodiagnosis studies – could facilitate much needed larger scale studies on infectiousness of human subgroups. In addition, we advocate further evaluation of this device as a diagnostic tool for PKDL.
Guiding Myocardial Revascularization by Algorithmic Interpretation of FFR Pullback Curves: A Proof of Concept Study
Authors: Argacha Jean-François , Decamp Jean , Vandeloo Bert , Babin Danilo , Lochy Stijn , Van den Bussche Karen , de Hemptinne Quentin , Xaplanteris Panagiotis , Magne Julien , Segers Patrick , Cosyns Bernard 
Published: March 2021

Background: Coronary artery disease distribution along the vessel is a main determinant of FFR improvement after PCI. Identifying focal from diffuse disease from visual inspections of coronary angiogram (CA) and FFR pullback (FFR-PB) are operator-dependent. Computer science may standardize interpretations of such curves.Methods: A virtual stenting algorithm (VSA) was developed to perform an automated FFR-PB curve analysis. A survey analysis of the evaluations of 39 vessels with intermediate disease on CA and a distal FFR &lt;0.8, rated by 5 interventional cardiologists, was performed. Vessel disease distribution and PCI strategy were successively rated based on CA and distal FFR (CA); CA and FFR-PB curve (CA/FFR-PB); and CA and VSA (CA/VSA). Inter-rater reliability was assessed using Fleiss kappa and an agreement analysis of CA/VSA rating with both algorithmic and human evaluation (operator) was performed. We hypothesize that VSA would increase rater agreement in interpretation of epicardial disease distribution and subsequent evaluation of PCI eligibility.Results: Inter-rater reliability in vessel disease assessment by CA, CA/FFR-PB, and CA/VSA were respectively, 0.32 (95% CI: 0.17–0.47), 0.38 (95% CI: 0.23–0.53), and 0.4 (95% CI: 0.25–0.55). The raters' overall agreement in vessel disease distribution and PCI eligibility was higher with the VSA than with the operator (respectively, 67 vs. 42%, and 80 vs. 70%, both p &lt; 0.05). Compared to CA/FFR-PB, CA/VSA induced more reclassification toward a focal disease (92 vs. 56.2%, p &lt; 0.01) with a trend toward more reclassification as eligible for PCI (70.6 vs. 33%, p = 0.06). Change in PCI strategy did not differ between CA/FFR-PB and CA/VSA (23.6 vs. 28.5%, p = 0.38).Conclusions: VSA is a new program to facilitate and standardize the FFR pullback curves analysis. When expert reviewers integrate VSA data, their assessments are less variable which might help to standardize PCI eligibility and strategy evaluations.Clinical Trial Registration:https://www.clinicaltrials.gov/ct2/show/NCT03824600.
Elevated Plasma Big Endothelin-1 at Admission Is Associated With Poor Short-Term Outcomes in Patients With Acute Decompensated Heart Failure
Authors: Mo Ran , Yang Yan-min , Yu Li-tian , Tan Hui-qiong , Zhu Jun 
Published: March 2021

Objective: We aimed to evaluate the association between plasma big endothelin-1 (ET-1) at admission and short-term outcomes in acute decompensated heart failure (ADHF) patients.Methods: In this single-center, retrospective study, a total of 746 ADHF patients were enrolled and divided into three groups according to baseline plasma big ET-1 levels: tertile 1 (&lt;0.43 pmol/L, n = 250), tertile 2 (between 0.43 and 0.97 pmol/L, n = 252), and tertile 3 (&gt;0.97 pmol/L, n = 244). The primary outcomes were all-cause death, cardiac arrest, or utilization of mechanical support devices during hospitalization. Logistic regression analysis and net reclassification improvement approach were applied to assess the predictive power of big ET-1 on short-term outcomes.Results: During hospitalization, 92 (12.3%) adverse events occurred. Etiology, arterial pH, lactic acid, total bilirubin, serum creatine, serum uric acid, presence of atrial fibrillation and N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels were positively correlated with plasma big ET-1 level, whereas systolic blood pressure, serum sodium, hemoglobin, albumin, and estimated glomerular filtration rate were negatively correlated. In multivariate logistic regression, tertile 3 compared with tertile 1 had a 3.68-fold increased risk of adverse outcomes [odds ratio (OR) = 3.681, 95% confidence interval (CI) 1.410–9.606, p = 0.008]. However, such adverse effect did not exist between tertile 2 and tertile 1 (OR = 0.953, 95% CI 0.314–2.986, p = 0.932). As a continuous variable, big ET-1 level was significantly associated with primary outcome (OR = 1.756, 95% CI 1.413–2.183, p &lt; 0.001). The C statistic of baseline big ET-1 was 0.66 (95% CI 0.601–0.720, p &lt; 0.001). Net reclassification index (NRI) analysis showed that big ET-1 provided additional predictive power when combining it to NT-proBNP (NRI = 0.593, p &lt; 0.001).Conclusion: Elevated baseline big ET-1 is an independent predictor of short-term adverse events in ADHF patients and may provide valuable information for risk stratification.
Following Guidelines for Drug-Resistant Tuberculosis: “Yes, it’s a challenge”
Authors: Gray Adam T. , Wood Caroline E. , Boyles Tom , Luedtke Susanne , Birjovanu Georgiana , Hughes Jennifer , Kostkova Patty , Esmail Hanif 
Published: March 2021

BackgroundDrug-resistant tuberculosis (DR-TB) is a major contributor to antimicrobial resistance (AMR) globally and is projected to be responsible for up to a quarter of AMR-associated deaths in the future. Management of DR-TB is increasingly decentralised to primary healthcare settings, and simultaneously becoming more complex due to a growing range of treatment options (e.g. novel agents, shorter regimens). This is reflected in the numerous recent updates to international guidelines and as such understanding the barriers and enablers to how healthcare workers access and use guidelines is vital.Materials and MethodsWe used an established psychological framework – the theoretical domains framework (TDF) – to construct and analyse an online survey and focus groups to explore healthcare workers current use of DR-TB guidelines in South Africa. We aimed to identify barriers and enablers with which to direct future attempts at improving guideline use.ResultsThere were 19 responses to the online survey and 14 participants in two focus groups. 28% used the most up-to-date national guidelines, 79% accessed guidelines primarily on electronic devices. The TDF domains of ‘Social Influences’ (mean Likert score = 4.3) and ‘Beliefs about Consequences’ (4.2) were key enablers, with healthcare workers encouraged to use guidelines and also recognising the value in doing so. ‘Environmental Resources’ (3.7) and ‘Knowledge’ (3.3) were key barriers with limited, or variable access to guidelines and lack of confidence using them being notable issues. This was most noted for certain subgroups: children, HIV co-infected, pregnant women (2.7).DiscussionCurrent use of DR-TB guidelines in South Africa is suboptimal. Planned interventions should focus on overcoming the identified key barriers and might include an increased use of digital tools.
Soluble Epoxide Hydrolase Inhibition Prevents Experimental Type 4 Cardiorenal Syndrome
Authors: Hamzaoui Mouad , Roche Clothilde , Coquerel David , Duflot Thomas , Brunel Valery , Mulder Paul , Richard Vincent , Bellien Jérémy , Guerrot Dominique 
Published: March 2021

Objectives: Cardiovascular diseases (CVD) remain the leading cause of morbimortality in patients with chronic kidney disease (CKD). The aim of this study was to assess the cardiovascular impact of the pharmacological inhibition of soluble epoxide hydrolase (sEH), which metabolizes the endothelium-derived vasodilatory and anti-inflammatory epoxyeicosatrienoic acids (EETs) to dihydroxyeicosatrienoic acid (DHETs), in the 5/6 nephrectomy (Nx) mouse model.Methods and Results: Compared to sham-operated mice, there was decrease in EET-to-DHET ratio 3 months after surgery in vehicle-treated Nx mice but not in mice treated with the sEH inhibitor t-AUCB. Nx induced an increase in plasma creatinine and in urine albumin-to-creatinine ratio as well as the development of kidney histological lesions, all of which were not modified by t-AUCB. In addition, t-AUCB did not oppose Nx-induced blood pressure increase. However, t-AUCB prevented the development of cardiac hypertrophy and fibrosis induced by Nx, as well as normalized the echocardiographic indices of diastolic and systolic function. Moreover, the reduction in endothelium-dependent flow-mediated dilatation of isolated mesenteric arteries induced by Nx was blunted by t-AUCB without change in endothelium-independent dilatation to sodium nitroprusside.Conclusion: Inhibition of sEH reduces the cardiac remodelling, and the diastolic and systolic dysfunctions associated with CKD. These beneficial effects may be mediated by the prevention of endothelial dysfunction, independent from kidney preservation and antihypertensor effect. Thus, inhibition of sEH holds a therapeutic potential in preventing type 4 cardiorenal syndrome.