bluuebunny/crossref_metadata_2025_split huggingface dataset:
Structural design process and subsequent flight mechanical evaluation in preliminary aircraft design: demonstrated on passenger ride comfort assessment
Authors: Krishnamurthy Vikram , Handojo Vega 
Published: April 2021

AbstractNew fuel-efficient aircraft designs have high aspect ratio wings. Consequently, those aircraft are more flexible. Additionally, load alleviation functions are implemented to reduce the structural loads, which results in further reductions of the structural stiffness. At the same time, the structural design impacts other disciplines in preliminary aircraft design, especially flight mechanics. For example, it is important to know how at that design stage such flexible aircraft with load alleviation affect passenger ride comfort in turbulent flight. For an efficient design process, it is essential to answer such questions with accurate multi-disciplinary tools and methods as early as possible to minimize development risk and avoid costly and time-consuming redesign loops. Current available tools and methods are not accurate enough for this task. To address this issue, the DLR MONA based design and the TUB flight mechanical assessment tool MITRA are linked to investigate the impact of the structural design on specific flight mechanical assessments such as passenger ride comfort. This is particularly interesting since the implemented load alleviation functions are designed to reduce loads, and not explicitly to improve passenger ride comfort. By conducting this assessment for a particular aircraft configuration, more insight into passenger ride comfort and the key contributors can be gained during preliminary design. This paper describes the combined toolchain and its application on a generic long-range reference aircraft to investigate the effects of load alleviation functions on passenger ride comfort and discusses the results.
The role of PoCUS in the assessment of COVID-19 patients
Authors: Karp John , Burke Karina , Daubaras Sarah-Marie , McDermott Cian 
Published: April 2021

AbstractThe Coronavirus disease 19 (COVID-19) pandemic has increased the burden of stress on the global healthcare system in 2020. Point of care ultrasound (PoCUS) is used effectively in the management of pulmonary, cardiac and vascular pathologies. POCUS is the use of traditional ultrasound imaging techniques in a focused binary manner to answer a specific set of clinical questions. This is an imaging technique that delivers no radiation, is inexpensive, ultraportable and provides results instantaneously to the physician operator at the bedside. In regard to the pandemic, PoCUS has played a significant adjunctive role in the diagnosis and management of co-morbidities associated with COVID-19. PoCUS also offers an alternative method to image obstetric patients and the pediatric population safely in accordance with the ALARA principle. Finally, there have been numerous PoCUS protocols describing the effective use of this technology during the COVID-19 pandemic.
Does laser surface texturing really have a negative impact on the fatigue lifetime of mechanical components?
Authors: Hsu Chia-Jui , Stratmann Andreas , Medina Simon , Jacobs Georg , Mücklich Frank , Gachot Carsten 
Published: April 2021

AbstractLaser surface texturing (LST) has been proven to improve the tribological performance of machine elements. The micro-scale patterns manufactured by LST may act as lubricant reservoirs, thus supplying oil when encountering insufficient lubrication. However, not many studies have investigated the use of LST in the boundary lubrication regime, likely due to concerns of higher contact stresses that can occur with the increasing surface roughness. This study aims to examine the influence of LST on the fatigue lifetime of thrust rolling bearings under boundary lubrication. A series of periodic patterns were produced on the thrust rolling bearings, using two geometrically different designs, namely cross and dimple patterns. Base oil ISO VG 100 mixed with 0.05 wt% P of zinc dialkyldithiophosphate (ZDDP) was supplied. The bearings with cross patterns reduce the wear loss by two orders of magnitude. The patterns not only retain lubricant in the textured pockets but also enhance the formation of an anti-wear tribofilm. The tribofilm generation may be improved by the higher contact stresses that occur when using the textured surface. Therefore, in contrast to the negative concerns, the ball bearings with cross patterns were instead found to increase the fatigue life by a factor of three.
Benefit segmentation in the tourist accommodation market based on eWOM attribute ratings
Authors: Nessel Karolina , Kościółek Szczepan , Wszendybył-Skulska Ewa , Kopera Sebastian 
Published: April 2021

AbstractGiven the increasing importance of electronic word-of-mouth (eWOM) in the global tourism market, the purpose of the study was to estimate weights customers assign to main attributes of tourist accommodations embodied in easily observed eWOM numerical ratings and subsequently to determine segments of customers with homogenous preferences. To this goal, the preferences tourists attach to price and seven other accommodation attributes rated by Internet users on Booking.com were revealed with the analytical hierarchy process (AHP). Next, a two-stage clustering procedure based on these preferences was undertaken followed by profiling of the clusters in terms of their socio-demographics and travel characteristics. The results show that even if the ranking of the attributes is roughly the same for all the segments (with cleanliness, value for money, and location always in top four), all eight attributes effectively segment tourists into three clusters: “quality-seekers” (45% of the market), “bargain-seekers” (35%), and “cleanliness-seekers” (20%). The segments differ in terms of tourists’ income and expenditures, type of accommodation, actual payer for accommodation, and trip purpose. In contrast, socio-demographics, and most tourists stay variables are alike across the segments. The proposed method of benefit segmentation provides a new perspective for an exploitation of eWOM data by accommodation providers in their marketing strategy.
Modeling of the Split-Hopkinson-Pressure-Bar experiment with the explicit material point method
Authors: Maassen S. F. , Niekamp R. , Bergmann J. A. , Pöhl F. , Schröder J. , Wiederkehr P. 
Published: April 2021

AbstractThe material point method (MPM) represents an alternative discretization method for numerical simulations. It aims to combine the benefits of a Lagrangian representation of bodies and an Eulerian numerical solution approach. Therefore, especially at high material deformations the method is not prone to mesh distortions such as the finite element method (FEM). For this reason, the MPM is used to a great extent for modeling granular materials as in geo-mechanics. However, high deformations occur in many industrial processes on metallic materials. The Split-Hopkinson-Pressure-Bar (SHPB) experiment is used to characterize material properties at high deformation rates. Although widely used, this experiment is not yet standardized and shows a variety of sensitivities, e.g. to friction. Inter alia for this reason, simulations are conducted with the experiment to allow for a better evaluation of the measured data. The purpose of this work from an engineering point of view is to analyze the performance of the MPM on an SHPB experiment. In order to validate the experimental results for the material characterization under dynamic loading conditions we introduce frictional contact. We use arbitrary tri-linear brick domains in a 3D CPDI1 scheme, instead of originally used parallelepipeds. This allows for a more flexible geometry approximation using standard meshes. The results of the method are analyzed with respect to discretization sensitivity and discussed in the context of the experimental results for a 42CrMo4 steel. We were able to show that the method is capable to reproduce the SHPB experiment. Additionally the method shows convergency in the results with finer discretizations. Thus, the MPM has underlined its importance as an alternative simulation technique for problems with high deformation.
Data science: a game changer for science and innovation
Authors: Grossi Valerio , Giannotti Fosca , Pedreschi Dino , Manghi Paolo , Pagano Pasquale , Assante Massimiliano 
Published: April 2021

AbstractThis paper shows data science’s potential for disruptive innovation in science, industry, policy, and people’s lives. We present how data science impacts science and society at large in the coming years, including ethical problems in managing human behavior data and considering the quantitative expectations of data science economic impact. We introduce concepts such as open science and e-infrastructure as useful tools for supporting ethical data science and training new generations of data scientists. Finally, this work outlines SoBigData Research Infrastructure as an easy-to-access platform for executing complex data science processes. The services proposed by SoBigData are aimed at using data science to understand the complexity of our contemporary, globally interconnected society.
Mitigation of Atmospheric Artefacts in Multi Temporal InSAR: A Review
Authors: Kirui Pius Kipng’etich , Reinosch Eike , Isya Noorlaila , Riedel Björn , Gerke Markus 
Published: April 2021

AbstractThe complexity of the atmosphere renders the modelling of the atmospheric delay in multi temporal InSAR difficult. This limits the potential of achieving millimetre accuracy of InSAR-derived deformation measurements. In this paper we review advances in tropospheric delay modelling in InSAR, tropospheric correction methods and integration of the correction methods within existing multi temporal algorithms. Furthermore, we investigate ingestion of the correction techniques by different InSAR applications, accuracy performance metrics and uncertainties of InSAR derived measurements attributed to tropospheric delay. Spatiotemporal modelling of atmospheric delay has evolved and can now be regarded as a spatially correlated turbulent delay with varying degree of anisotropy random in time and topographically correlated seasonal stratified delay. Tropospheric corrections methods performance is restricted to a case by case basis and ingestion of these methods by different applications remains limited due to lack of their integration into existing algorithms. Accuracy and uncertainty assessments remain challenging with most studies adopting simple statistical metrics. While advances have been made in tropospheric modelling, challenges remain for the calibration of atmospheric delay due to lack of data or limited resolution and fusion of multiple techniques for optimal performance.
Simpson type inequalities and applications
Authors: Awan Muhammad Uzair , Javed Muhammad Zakria , Rassias Michael Th. , Noor Muhammad Aslam , Noor Khalida Inayat 
Published: April 2021

AbstractA new generalized integral identity involving first order differentiable functions is obtained. Using this identity as an auxiliary result, we then obtain some new refinements of Simpson type inequalities using a new class called as strongly (s, m)-convex functions of higher order of $$\sigma >0$$

σ
>
0

. We also discuss some interesting applications of the obtained results in the theory of means. In last we present applications of the obtained results in obtaining Simpson-like quadrature formula.
Negotiating Ethics-in-Action in a Long-term Research Relationship with a Young Child
Authors: Rutanen Niina , Raittila Raija , Harju Kaisa , Lucas Revilla Yaiza , Hännikäinen Maritta 
Published: April 2021

AbstractThis article continues the discussions of relational ethics put forward in Human Arenas in “Arena of Ethics” (Hilppö et al., 2019). Our aim in this article is to explore and discuss relational ethics, as ethics-in-action, in a long-term research relationship with a child. Our question is: How is ethics-in-action negotiated during critical incidents in the construction of a research space that involves a long-term research relationship with a young child? This article is based on a research project that focused on children’s transitions in early childhood education and care (ECEC). These transitions include the transition from home care to ECEC as well as transitions from child groups or settings to other ECEC groups or settings, and the transition to pre-primary education. We apply a particular lens to the corpus of data, analyzing and reflecting critical incidents vis-à-vis a negotiation of ethics-in-action during the construction of our research space, which involved a long-term research relationship with a child. Our results show that critical incidents in our study’s negotiation of ethics-in-action included (a) the focus child’s spontaneous contributions to the study’s interviews, (b) interdependencies between the child and diverse researchers, and (c) the child’s evolving expertise in data collection, which restructured our study’s research space. We conclude that ethical questions cannot be separated from the mutually constituted relationships or socio-spatial context in where they emerge; thus, they are relationally and spatially embedded.
Bias-inducing allosteric binding site in mu-opioid receptor signaling
Authors: Marmolejo-Valencia Andrés F. , Madariaga-Mazón Abraham , Martinez-Mayorga Karina 
Published: April 2021

Abstract
G-protein-biased agonism of the mu-opioid receptor (μ-OR) is emerging as a promising strategy in analgesia. A deep understanding of how biased agonists modulate and differentiate G-protein-coupled receptors (GPCR) signaling pathways and how this is transferred into the cell are open questions. Here, using extensive all-atom molecular dynamics simulations, we analyzed the binding recognition process and signaling effects of three prototype μ-OR agonists. Our suggested structural mechanism of biased signaling in μ-OR involves an allosteric sodium ion site, water networks, conformational rearrangements in conserved motifs and collective motions of loops and transmembrane helices. These analyses led us to highlight the relevance of a bias-inducing allosteric binding site in the understanding of μ-OR’s G-protein-biased signaling. These results also suggest a competitive equilibrium between the agonists and the allosteric sodium ion, where the bias-inducing allosteric binding site can be modulated by this ion or an agonist such as herkinorin. Notably, herkinorin arises as the archetype modulator of μ-OR and its interactive pattern could be used for screening efforts via protein–ligand interaction fingerprint (PLIF) studies.

Article highlights

Agonists and a sodium ion compete for the bias-inducing allosteric binding site that modulates signaling in mu-opioid receptors.

Molecular dynamics simulations of the prototype μ-OR agonist suggest a competitive equilibrium involving the agonist and an allosteric sodium ion.

Analysis of experimental data from the literature and molecular models provides the structural bases of biased agonism on μ-OR.
A Wavelet-Free Approach for Multiresolution-Based Grid Adaptation for Conservation Laws
Authors: Gerhard Nils , Müller Siegfried , Sikstel Aleksey 
Published: April 2021

AbstractIn recent years the concept of multiresolution-based adaptive discontinuous Galerkin (DG) schemes for hyperbolic conservation laws has been developed. The key idea is to perform a multiresolution analysis of the DG solution using multiwavelets defined on a hierarchy of nested grids. Typically this concept is applied to dyadic grid hierarchies where the explicit construction of the multiwavelets has to be performed only for one reference element. For non-uniform grid hierarchies multiwavelets have to be constructed for each element and, thus, becomes extremely expensive. To overcome this problem a multiresolution analysis is developed that avoids the explicit construction of multiwavelets.
A versatile heterogeneous photocatalyst: nanoporous gold powder modified with a zinc(II) phthalocyanine derivative for singlet oxygen [4 + 2] cycloadditions
Authors: Steinebrunner David , Schnurpfeil Günter , Doebler Hans Hannes , Tapia Burgos Jorge Adrian , Wöhrle Dieter , Wittstock Arne 
Published: April 2021

AbstractNanoporous gold was functionalized with a photosensitizer, a zinc(II) phthalocyanine derivative. Such systems are active for the generation of reactive singlet oxygen which can be used for photocatalytic oxidation reactions. This study aims to demonstrate the versatility of such an approach, in terms of substrates and the employed solvent, only possible for a truly heterogeneous catalytic system. The activity of the hybrid system was studied for [4 + 2] cycloadditions of three different types of dienes and a total of eight substrates in two organic solvents and once in water. The highest activity was measured for 1,3-diphenylisobenzofuran, which is also highest in terms of sensitivity for the reaction with 1O2. Trends in conversion could be anticipated based on reported values for the rate constant for the reaction of 1O2. In almost all cases, an amplification of the conversion by immobilization of the sensitizer onto nanoporous gold was observed. The limiting case was ergosterol, which was the largest of all substrates with a van-der-Waals radius of about 2.1 nm. Additional factors such as the limited lifetime of 1O2 in different solvents as well as the hampered diffusion of the substrates were identified.
Graphic abstract
India Fighting COVID-19: Experiences and Lessons Learned From the Successful Kerala and Bhilwara Models
Authors: Chandra Rishita , Sinha Smita 
Published: April 2021

AbstractThe COVID-19 pandemic marks its emergence in China in December 2019. India reported its first case on January 30th 2020 which happened to be epidemiologically linked to China. On March 24, India went into nationwide lockdown. The number of cases increased in the country and a few hotspots were identified. Cluster containment strategy seemed to be effective in containing the disease and breaking the chain of transmission. Two models (Kerala and Bhilwara) emerged as a lesson for other states. Kerala government implemented a “triple-lock containment strategy” and Bhilwara district administration followed “all down curfew” with massive sample testing. The experiences from these successful field models can be implemented in other districts and states to flatten the COVID-19 curve.
Mary Parker Follett as Integrative Public Philosopher
Authors: Brown Matthew J. 
Published: April 2021

AbstractMary Parker Follett was a feminist-pragmatist American philosopher, a social-settlement worker, a founding figure in the community centers movement, a mediator of labor disputes, and a theorist of political and social organization and management. I argue that she is a model for a certain kind of public philosopher, and I unpack the respects in which she serves as such a model. I emphasize both her virtues as a public thinker and the role played in her work by the process of integration and the creative process.
The role of procalcitonin results in antibiotic decision-making in coronavirus disease 2019 (COVID-19)
Authors: Fabre Valeria , Karaba Sara , Amoah Joe , Robinson Matthew , Jones George , Dzintars Kathryn , Katz Morgan , Landrum B. Mark , Qasba Sarojini , Gupta Pooja , Klein Eili , Cosgrove Sara E. 
Published: April 2021

AbstractObjective:To evaluate the role of procalcitonin (PCT) results in antibiotic decisions for COVID-19 patients at hospital presentation.Design, setting, and participants:Multicenter retrospective observational study of patients ≥18 years hospitalized due to COVID-19 at the Johns Hopkins Health system. Patients who were transferred from another facility with >24 hours stay and patients who died within 48 hours of hospitalization were excluded.Methods:Elevated PCT values were determined based on each hospital’s definition. Antibiotic therapy and PCT results were evaluated for patients with no evidence of bacterial community-acquired pneumonia (bCAP) and patients with confirmed, probable, or possible bCAP. The added value of PCT testing to clinical criteria in detecting bCAP was evaluated using receiving operating curve characteristics (ROC).Results:Of 962 patients, 611 (64%) received a PCT test. ROC curves for clinical criteria and clinical criteria plus PCT test were similar (at 0.5 ng/mL and 0.25 ng/mL). By bCAP group, median initial PCT values were 0.58 ng/mL (interquartile range [IQR], 0.24–1.14), 0.23 ng/mL (IQR, 0.1–0.63), and 0.15 ng/mL (IQR, 0.09–0.35) for proven/probable, possible, and no bCAP groups, respectively. Among patients without bCAP, an elevated PCT level was associated with 1.8 additional days of CAP therapy (95% CI, 1.01–2.75; P < .01) compared to patients with a negative PCT result after adjusting for potential confounders. Duration of CAP therapy was similar between patients without a PCT test ordered and a low PCT level for no bCAP and possible bCAP groups.Conclusions:PCT results may be abnormal in COVID-19 patients without bCAP and may result in receipt of unnecessary antibiotics.
An outer shelf shelly fauna from Cambrian Series 2 (Stage 4) of North Greenland (Laurentia)
Authors: Peel John S. 
Published: April 2021

AbstractAn assemblage of 50 species of small shelly fossils is described from Cambrian Series 2 (Stage 4) strata in North Greenland, the present day northernmost part of the paleocontinent of Laurentia. The fossils are derived from the basal member of the Aftenstjernesø Formation at Navarana Fjord, northern Lauge Koch Land, a condensed unit that accumulated in a sediment-starved outer ramp setting in the transarctic Franklinian Basin, on the Innuitian margin of Laurentia. Most other small shelly fossil assemblages of similar age and composition from North America are described from the Iapetan margin of Laurentia, from North-East Greenland south to Pennsylvania. Trilobites are uncommon, but includeSerrodiscus. The Australian bradoriidSpinospitellais represented by a complete shield.Obolella crassais the only common brachiopod. Hyoliths, includingCassitella,Conotheca,Neogloborilus, andTriplicatella, are abundant and diverse, but most are represented just by opercula. Sclerites interpreted as stem-group aculiferans (sachitids) are conspicuous, includingQaleruaqia, the oldest described paleoloricate,Ocruranus?,Inughuitoconusn. gen., andHippopharangites. Helcionelloid mollusks are diverse, but not common; they are associated with numerous specimens of the bivalvePojetaia runnegari. The fauna compares best with that of the upper Bastion Formation of North-East Greenland, the Forteau Formation of western Newfoundland, and the Browns Pond Formation of New York, but several taxa have a world-wide distribution. Many specimens are encrusted with crystals of authigenic albite. New species:Anabarella?navaranae,Stenotheca?higginsi,Figurina?polaris,Hippopharangites groenlandicus,Inughuitoconus borealis, andOcruranus?kangerluk.UUID:http://zoobank.org/160a17b1-3166-4fcf-9849-a3cabd1e04a3
Victims of Compromise: The Elizabethan Psalm Tunes
Authors: TEMPERLEY NICHOLAS 
Published: April 2021

AbstractThe music of The Whole Book of Psalms (first printed in 1562) was not a product of English tradition, but a new congregational system brought home from Geneva. Psalm tunes in Edward VI’s time had been secular, iambic and based on dance rhythms; in so far as Thomas Sternhold’s metrical psalms were sung in church, they were chanted by choirs to Sarum tones. The tunes created for congregational use by the Marian exiles had to satisfy Calvin’s principle that they must be distinct from secular songs. They avoided strong rhythms and imitated the Huguenot psalter, which catered for a very different French prosody. Elizabethan congregations were enthusiastic about singing, but did not take to many of these tunes. Evidence shows a growing tendency for the printed tunes to be ignored in practice, and to be replaced by orally transmitted ‘common tunes’ restoring the secular Edwardian idiom. These, rather than the Elizabethan tunes, became the lasting model for the English hymn tune.