bluuebunny/crossref_metadata_2025_split huggingface dataset:
Agronomic characterization of sunflower cultivars for animal feeding in tropical conditions
Authors: Sousa Saulo Almeida , Leite Vagner Maximino , Almeida Vanessa de Oliveira , Pina Douglas dos Santos , Rufino Luana Marta de Almeida , Santos Aracele Vieira , Perazzo Alexandre Fernandes , Silva Thiago Carvalho da , Cirne Luis Gabriel Alves , Carvalho Gleidson Giordano Pinto de 
Published: September 2021

This study was developed to examine morpho-agronomic traits of 18 sunflower cultivars and identify superior cultivars in terms of grain yield, forage quality, or both, for animal feeding. Twenty-two morpho-agronomic traits related to plant development and architecture; earliness of maturity; grain yield (achenes); dry matter yield; and dry matter content were evaluated. Cultivars Hélio 253, Hélio 358, Embrapa 122, BRS 321, and Hélio 360 showed inflorescence at the final stage. Aguará 4 showed the lowest flowering rate, characterizing it as late-maturing. For grain yield, cultivars Charrua, Olisun 3, BRS 321, Paraíso 103CL, Paraíso 65, Aguará 6, and CF 101 are recommended, as they showed the highest achene yields (average: 1,541.67 to 2,148.81 kg.ha−1, respectively). Cultivars Charrua, Hélio 251, Olisun 3, Hélio 360, Paraíso 55, and Paraíso 103CL exhibited higher dry matter yields (9,550.93 to 11,789.91 kg ha−1) and were thus indicated for forage production. Cultivars Charrua, Olisun 3, BRS 321, Paraíso 103CL, Paraíso 65, Aguará 6, and CF 101 are recommended for grain yield, for the diet of monogastric animals; Charrua, Hélio 251, Olisun 3, Hélio 360, Paraíso 55, and Paraíso 103CL for forage yield, for ruminant feeding; and Charrua, Olisun 3, and Paraíso 103CL for both purposes.
Analytical epidemiology of multiple sclerosis in the Republic of Kabardino-Balkaria
Authors: Tlapshokova L. B. , Zikhova A. R. 
Published: September 2021

Multiple sclerosis (MS) is a common autoimmune disease, which etiology includes a complex of genetic and environmental factors. Data suggests that their interaction can influence the age of the clinical manifestations and the course of the disease. Therefore, the study of risk factors of MS in regions with different ethnic compositions of the population and climatic and geographical characteristics is of considerable interest.Objective: to study MS risk factors prevalence in the Republic of Kabardino-Balkaria (RKB).Patients and methods. This case-control study of the representation of risk factors included a cohort of 112 MS patients living in two regions of the RKB (Nalchik and the Prokhladnensky district). The MS diagnosis was established with the McDonald criteria (2017). MS risk factors were assessed with a unified questionnaire. 112 respondents (matched by the main demographic characteristics and place of residence) were included in the control group.Results and discussion. MS patients from the Prokhladnensky district were significantly more likely to contact harmful chemical compounds, had higher consumption of smoked meat products; and suffered from viral infections more often (all differences were significant, p<0.05). More patients with MS, regardless of their place of residence, had a history of scarlet fever than the controls (n=23; 19.5% and n=14; 13.4%, ratio indicator 0.43 (95% CI 0.32–1.01), p=0.041), and the maximum significance of this factor was found in patients who suffered from scarlet fever after the age of 15 years (n=7; 6.3% and n=1; 0.9%, ratio indicator 2.45 (95% CI 1.92–3.21), p=0.041). More patients with MS had a history of chickenpox (n=70; 62.5% and n=55; 41.1%; ratio indicator 0.78 (95% CI 0.65–0.94, p=0.032), the frequency of this factor was most significant in early (up to 7 years) disease onset. Regardless of the place of residence, patients with MS were more likely to suffer from tonsillitis and sinusitis in childhood (p=0.032).Conclusion. In the RKB, as in other regions of the Russian Federation, the risk of MS, along with a genetic predisposition, is primarily determined by environmental factors, such as contact with potentially harmful chemicals, history of somatic diseases, characteristics of the ecological situation, etc. Therefore, MS risk is higher in people exposed to these factors before the age of 7 years and does not depend on the place of residence.
Clinical and epidemiological characteristics of multiple sclerosis in students in the Republic of Bashkortostan
Authors: Tukhvatullin A. V. , Kuzmina U. Sh. , Utyagulova N. F. , Talisov R. F. , Vakhitov V. A. , Bakhtiyarova K. Z. 
Published: September 2021

An expansion of the age range of multiple sclerosis (MS) manifestation has been reported recently. Considering the multifactorial etiology, high heterogeneity of the clinical symptoms, and the difficulties of early MS diagnosis in young people, the onset and course of this disease in students can be considered as one of the significant medical and social problems.Objective: to analyze the clinical and epidemiological characteristics of MS in university and secondary specialized educational institutions students in the Republic of Bashkortostan (RB).Patients and methods. This case-control study included 32 patients aged 15 to 24 years studying in universities and secondary schools of the RB. The clinical and epidemiological indicators analysis was carried out based on data from the register of MS patients in the RB. 32 sex-, age-, place of birth and residence-matching patients with MS, who were not students, were included in the control group.Results and discussion. The median age of disease manifestation in students was 18 [16.5; 20] years, in the control group – 16 [14; 19] years (p=0.010). We found a lower «disease onset – diagnosis» in the students group of revealed a lower interval «disease onset – diagnosis» (0.5 [0; 1] years, p=0.006), and a shorter duration of MS compared to the control group ((2.8 [2; 4] years and 4 [2; 7] years, respectively, p=0.020). Students with MS predominantly had movement disorders: central paresis and cerebellar ataxia. Students also had a faster MS progression (0.4 [0.2; 0.6] EDSS scores per year, p=0.001), despite of the disease-modifying therapies.Conclusion. MS manifestation and course in students receiving disease-modifying therapies indicate the need for close follow-up, adherence control, and psychological support in the educational process.
Art therapy possibilities in the complex treatment of patients with multiple sclerosis
Authors: Guseva M. E. , Matvievskaya O. V. , Boyko A. N. 
Published: September 2021

Objective: to study the effectiveness of art therapy methods in the complex treatment of neuropsychological disorders and quality of life improvement in patients with relapsing-remitting and secondary-progressive multiple sclerosis (MS).Patients and methods. A group of 42 patients (5 men and 37 women, mean age 32.9 years, mean EDSS severity 3.8 points) with MS underwent outpatient continuous active art therapy cycle. The mean group training cycle duration was six months. The comparison group included 15 age- and sex-adjusted individuals without neurological disorders. Tests on various drawing topics were carried out before and after a three-month therapy course. We used Hospital Anxiety and Depression Scale (HADS) to assess the severity of anxiety and depression and the SF-36 scale to evaluate the quality of life (QoL).Results and discussion. Before the art therapy start, light blue, yellow, pink, blue, and green colors prevailed in the drawings. There was no predominance of any color depending on MS severity or course. The green color predominated in this test in the control group, and the light blue color was significantly less represented. The art therapy course did not lead to a significant change in the severity of MS according to the Expanded Disability Status Scale (EDSS). After the art therapy course, the color scheme of the drawings was mainly represented by red, light blue, green, yellow, and blue colors. In addition, a red-orange color appeared in the drawings, which was completely absent before the course. Positive trends were noted according to HADS: a decrease in anxiety by 23% and depression by 19%. The physical component of QoL assessed by the SF-36 scale did not change substantially, but the psychological component significantly improved by 11%.Conclusion. The predominance of light blue color observed in MS is associated with damage to the nervous and musculoskeletal systems, and blue color – with psychological problems and depression. However, after a course of art therapy for MS, red, red-orange, yellow, and green colors representation increased significantly, which indicates an increase in positive attitude, a decrease in the level of depression, and an improvement in QoL.
Фаббинг: особенности аддиктивного поведения молодежи
Authors: Максименко Александр Александрович , Дейнека Ольга Сергеевна , Духанина Любовь Николаевна , Сапоровская Мария Вячеславовна 
Published: September 2021

В статье обобщены результаты зарубежных социологических и психологических исследований фаббинг-поведения и интернет-зависимости за последние 10 лет Описаны результаты эмпирического исследования российской молодежи (N = 525), выполненного авторами в 2019 г. с целью выявления аддикции от смартфонов и проявлений фаббинга в контексте межличностной зависимости (методика Р. Гиршфильда). В опросе приняли участие молодые люди из разных регионов России (72% девушек и 28% юношей; средний возраст 22,3 года). Подтверждены и конкретизированы половозрастные различия в зависимостях от гаджетов у молодежи. Выявлена связь фаббинг-поведения с неуверенностью в себе и потребностью в эмоциональной опоре и одобрении.
Phytochemistry and pharmacology of Celastrus paniculatus Wild.: a nootropic drug
Authors: Aleem Mohd 
Published: September 2021

Abstract

Objectives

Celastrus paniculatus Wild is an evergreen climbing shrub. The plant is of great significance in the traditional Indian System of Medicine, such as Ayurveda, Unani, and Siddha. The seeds and their oil are extensively used to treat neurological disorders such as cognitive dysfunction, paralysis, epilepsy, insomnia, and other ailments like rheumatism, arthritis, sciatica, and leprosy. This paper aims to highlight the nootropic activity of C. paniculatus and explore its phytochemistry, traditional uses, and other pharmacological activities.

Methods
All available information concerning C. paniculatus has been searched in the internationally accepted scientific databases, including PubMed, ScienceDirect, Scopus, and Google Scholar. Additional knowledge was gathered from the classical Textbooks and Unani Pharmacopoeia.

Results

C. paniculatus is a rich source of several secondary metabolites, such as β-Dihydroagarofuranoids sesquiterpenes, alkaloids (Celastrine, Celapanin, Celapagin, and paniculatin), flavonoids, terpenoid (β-amyrin, Lupeol, Pristimerin), sterols (β-sitosterol, campesterol, stigmasterol, α-tocopherol, γ-Tocopherol), fatty acid (palmitic, stearic, oleic, linoleic, linolenic acids) and non-fatty acids (Benzoic acid, Cinnamic acid). The various study shows that the extracts and active constituent of this plant possess potent nootropic activity. Besides nootropic activity, it has also been reported for anti-Alzheimer, anticonvulsant, antidepressant, antioxidant, analgesic, anti-inflammatory, antiarthritic, gastroprotective, anti-psoriatic, wound healing, antibacterial, antimalarial, and several other properties.

Conclusions
Several in vitro and in vivo trials confirm the conventional use of C. paniculatus in cognitive dysfunction. However, the relations between the possible mechanisms of other activities and traditional uses of the C. paniculatus remain indistinct. Still, pharmacological studies also explored the effects of C. paniculatus, which were not recognized in ancient times, such as cytotoxic, ACE inhibitor, and antidiabetic activities. These discoveries are may be beneficial in the development of the new drug to treat various diseases. It is also confirmed that the β-dihydroagarofuranoids exhibit significant AChE inhibitory, cytotoxic, antibacterial, and insecticidal effects. This versatile medicine is truly a life elixir. Considering the therapeutic importance of the C. paniculatus and the absence of any reported clinical studies, extensive clinical trials are needed to explore its memory enhancing and other activities.
Myocardial deformation analysis in late-onset small-for-gestational-age and growth-restricted fetuses using two-dimensional speckle tracking echocardiography: a prospective cohort study
Authors: Graupner Oliver , Ried Christina , Wildner Nadia K. , Ortiz Javier U. , Kuschel Bettina , Haller Bernhard , Oberhoffer Renate , Wacker-Gußmann Annette , Lobmaier Silvia M. 
Published: September 2021

Abstract

Objectives
An association between fetal growth restriction (FGR) and increased predisposition to cardiovascular disease (CVD) is suggested. The aim of this study was to evaluate subclinical signs of fetal cardiac remodeling in late-onset small-for-gestational-age (SGA) and growth-restricted fetuses using two-dimensional speckle tracking echocardiography (2D-STE).

Methods
This is a prospective cohort study, including 117 late-onset (≥32 weeks) SGA (birthweight≤10th centile) fetuses and 102 gestational age matched controls. A subgroup analysis was performed: FGR was defined based on either BW (<third centile) or the presence of feto-maternal Doppler abnormalities, the remaining cases were called SGA centile 3–10. 2D-STE based myocardial deformation analyses included longitudinal peak systolic strain (LPSS) and strain rate (LSR) of the global left (LV) or right (RV) ventricle and its individual segments.

Results
Global and segmental LPSS and LSR values showed no significant difference between late-onset SGA and control fetuses for both ventricles (p>0.05). Regarding global and segmental LPSS and LSR values of LV/RV, subgroup analysis revealed no significant difference between the FGR (n=81), SGA centile 3–10 (n=36) and control group.

Conclusions
A mild degree of placental dysfunction seems not to influence myocardial deformation properties measured by 2D-STE.
A Quantitative Study of the Linear Pottery Culture Cemetery “Aiterhofen-Ödmühle”
Authors: Hahnekamp Yanik 
Published: September 2021

Abstract
This article emphasises on the results of the master´s thesis “Burials in Bytes. A Quantitative Study of Linear Pottery Cemeteries in Austria, Bohemia, Moravia and Southern Germany” and further elaborates on interpretations of identified patterns at Early Neolithic cemeteries. The focus will lie on the Lower Bavarian site “Aiterhofen-Ödmühle.” Although the cemetery was subject to different analyses and interdisciplinary research in the past, there are still unsolved issues regarding chronology, structure, meaning of the local mortuary rites and rules, and its significance in the superregional context. The study utilised data acquisition via the Montelius image database and quantitative methods performed through the softwares WinSerion and Google Mapper. These data consisted of various typologies and classifications, while several variations of correspondence analysis, seriation, Analysis N Next Neighbours, and the creation of distribution maps have been involved in the process of evaluation. The results of the evaluations of Aiterhofen-Ödmühle favour a chronological south–north progression. Inhumations and cremations differ in grave good equipment, potentially representing contrasts in gender distribution. Spatial groupings are distinguishable through their properties – open to various ways of interpretation and comparable to clusters of other cemeteries. Differences regarding age and sex were also highlighted. Overall, Aiterhofen-Ödmühle stands out among Early Neolithic cemeteries through region-specific grave goods and death gesture, local peculiarities, variation of burial types, and its site structure. Similarities to other sites include characteristic Linear Pottery traits, although less obvious connections can also be recognised through the quantitative evaluations. Instead of rigid funerary rules, dynamic and flexible rites are suggested.
Cronología de la Academia Costarricense de la Lengua
Authors: Agüero Chaves Arturo 
Published: September 2021

La revista LETRAS ofrece en este número un interesante documento, escrito por el ilustre filólogo, lingüista y poeta Arturo Agüero Chaves (1907-2001), en el que se hace un minucioso e interesante recuento de la trayectoria de la Academia Costarricense de la Lengua. Agüero le dio un particular impulso a esa corporación, de la que fue su Director durante muchos años. El documento que aquí se reproduce, redactado hacia 1989, pone en una nueva perspectiva el trabajo llevado a cabo por quienes han integrado en sus diversas etapas esa institución. Se completa esta sección con la nómina histórica de quienes sucesivamente han ocupado las diecinueve sillas de la Academia, desde su fundación en 1923. LETRAS agradece a la actual Academia Costarricense de la Lengua la cesión de esos documentos y su autorización para publicarlos en este número.
Six Stages of Engagement in ADHD Treatment Described by Diverse, Urban Parents
Authors: Spencer Andrea E. , Sikov Jennifer , Loubeau J Krystel , Zolli Nicole , Baul Tithi , Rabin Megan , Hasan Syeda , Rosen Katherine , Buonocore Olivia , Lejeune Julia , Dayal Rohan , Fortuna Lisa , Borba Christina , Silverstein Michael 
Published: September 2021

BACKGROUND
Attention-deficit/hyperactivity disorder (ADHD) is a common neurodevelopmental condition in children. Although ADHD is treatable, barriers remain to engagement in treatment, especially among socioeconomically disadvantaged and racial and ethnic minority families. Our goal was to examine the process by which families engage in ADHD treatment and to identify targets for an intervention to improve engagement in care.

METHODS
We conducted in-depth semistructured qualitative interviews with 41 parents of diverse youth aged 3 to 17 years old in treatment of ADHD at an urban safety net hospital. Parents were asked about their journey through diagnosis and treatment, community attitudes about ADHD, and other factors influencing treatment access and decision-making. Transcripts were analyzed by using thematic analysis.

RESULTS
Of children with ADHD, 69.2% were male, 57.7% were Black or African American, and 38.5% were of Hispanic, Latino, or Spanish origin. Parents were 92.7% female, were 75.6% English speaking, and had a median income of $20 000. Parents described 6 stages to the process of engaging in care for their child’s ADHD, which unfolded like a developmental process: (1) normalization and hesitation, (2) fear and stigmatization, (3) action and advocacy, (4) communication and navigation, (5) care and validation, and (6) preparation and transition. Barriers often occurred at points of stage mismatch between parents and providers and/or systems. Difficulty resolving an earlier stage interfered with the progression through subsequent stages.

CONCLUSIONS
The 6 stages framework could be used to develop new strategies to measure engagement and to design family-centered interventions to facilitate engagement in ADHD treatment.
Internet-based treatment of gambling problems: A systematic review and meta-analysis of randomized controlled trials
Authors: Sagoe Dominic , Griffiths Mark. D. , Erevik Eilin Kristine , Høyland Turid , Leino Tony , Lande Ida Alette , Sigurdsson Mie Engen , Pallesen Ståle 
Published: September 2021

Abstract

Background and aims
The effect of internet-based psychological treatment for gambling problems has not been previously investigated by meta-analysis. The present study is therefore a quantitative synthesis of studies on the effects of internet-based treatment for gambling problems. Given that effects may vary according to the presence of therapist support and control conditions, it was presumed that subgroup analyses would elucidate such effects.

Methods
A systematic search with no time constraints was conducted in PsycINFO, MEDLINE, Web of Science, and the Cochrane Library. Two authors independently extracted data using a predefined form, including study quality assessment based on the Cochrane risk of bias tool. Effect sizes were calculated using random-effects models. Heterogeneity was indexed by Cochran’s Q and the I
2 statistics. Publication bias was investigated using trim and fill.

Results
Thirteen studies were included in the analysis. Random effects models at post-treatment showed significant effects for general gambling symptoms (g = 0.73; 95% CI = 0.43–1.03), gambling frequency (g = 0.29; 95% CI = 0.14–0.45), and amount of money lost gambling (g = 0.19; 95% CI = 0.11–0.27). The corresponding findings at follow-up were g = 1.20 (95% CI = 0.79–1.61), g = 0.36 (95% CI = 0.12–0.60), and g = 0.20 (95% CI = 0.12–0.29) respectively. Subgroup analyses showed that for general gambling symptoms, studies with therapist support yield larger effects than studies without, both post-treatment and at follow-up. Additionally, on general gambling symptoms and gambling frequency, there were lower effect sizes for studies with a control group compared to studies without a control group at follow-up. Studies with higher baseline severity of gambling problems were associated with larger effect sizes at both posttreatment and follow-up than studies with more lenient inclusion criteria concerning gambling problems.

Discussion and conclusions
Internet-based treatment has the potential to reach a large proportion of persons with gambling problems. Results of the meta-analysis suggest that such treatments hold promise as an effective approach. Future studies are encouraged to examine moderators of treatment outcomes, validate treatment effects cross-culturally, and investigate the effects of novel developments such as ecological momentary interventions.