bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neither operative nor nonoperative approach is superior for treating displaced midshaft clavicle fractures: a partially blinded randomized controlled clinical trial
Authors: Ban Ilija , Kristensen Morten Tange , Barfod Kristoffer Weisskirchner , Eschen Jacob , Kallemose Thomas , Troelsen Anders 
Published: April 2021

AimsTo compare the functionality of adults with displaced mid-shaft clavicular fractures treated either operatively or nonoperatively and to compare the relative risk of nonunion and reoperation between the two groups.MethodsBased on specific eligibility criteria, 120 adults (median age 37.5 years (interquartile range (18 to 61)) and 84% males (n = 101)) diagnosed with an acute displaced mid-shaft fracture were recruited, and randomized to either the operative (n = 60) or nonoperative (n = 60) treatment group. This randomized controlled, partially blinded trial followed patients for 12 months following initial treatment. Functionality was assessed by the Constant score (CS) (assessor blinded to treatment) and Disability of the Arm, Shoulder and Hand (DASH) score. Clinical and radiological evaluation, and review of patient files for complications and reoperations, were added as secondary outcomes.ResultsAt 12 months, 87.5% of patients (n = 105) were available for analysis. The two groups were well balanced based on demographic and fracture-related characteristics. At six weeks of follow-up a significant difference in DASH score (p < 0.001) was found in favour of operative treatment. The functionality at 12 months of follow-up based on CS and DASH was excellent in both groups (CS > 90 points and DASH < 10 points) with no significant difference (p = 0.277 for DASH and p = 0.184 for CS) between the two groups. The risk of symptomatic nonunion was significantly higher in the nonoperative group (p = 0.014), with a relative risk of 9.47 (95% confidence interval (CI) 1.26 to 71.53) in this group compared to the operative group. The number-needed-to-treat to avoid one symptomatic nonunion was 6.2. Initial treatment and age were factors significantly associated with nonunion in a logistic analysis. There were 26% in both groups (n = 14 in operative group and n = 15 in nonoperative group) who required secondary surgery, with most indications in the nonoperative group mandatory due to nonunion compared to most relative indications in the operative group requiring intervention due to implant irritation.ConclusionSuperiority was not identified with either an all-operative or all-nonoperative approach. The functionality at short term (within six weeks) seems igreater following operative treatment but was not found at one year. The risk of nonunion is significantly higher with nonoperative treatment. However, an all-operative approach to lower the nonunion risk may result in unnecessary surgery and is not recommended. Cite this article: Bone Joint J 2021;103-B(4):762–768.
Circularly polarized light emission from a GaN micro-LED integrated with functional metasurfaces for 3D display
Authors: Gao Xiang , Xu Yi , Huang Jinpeng , Hu Zelin , Zhu Wenhui , Yi Xiaoyan , Wang Liancheng 
Published: April 2021

This Letter proposes a circularly polarized (CP) light GaN micro-LED which is integrated with functional metasurfaces. The one-dimensional metallic nanograting can achieve a high transverse electric (TE) reflectivity (

R

T
E

) and extinction ratio (ER) of TE and transverse magnetic (TM) waves, which is highly polarized output for micro-LEDs. Besides, the nanograting, which is integrated on the bottom of the GaN layer, can also support a resonant cavity, together with the top distributed Bragg reflector, which can shape the radiation pattern. By optimizing the structure parameters of nanograting, the

R

T
E

achieves over 80%, and the ER reaches higher than 38 dB at 450 nm for the GaN micro-LED. Additionally, the metasurface, which acts as a quarter-wave plate, was investigated to control the phase delay between the polarization state of the electric wave in two orthogonal components. Finally, the circular shape of the transmitted pattern denotes the high performance of the metasurface which is integrated in the micro-LED for CP light emission. The work reported in this Letter might provide potential application in a 3D polarized light display.
Simple quantum key distribution using a stable transmitter-receiver scheme
Authors: Ma Di , Liu Xin , Huang Chunfeng , Chen Huasheng , Lin Huanbin , Wei Kejin 
Published: April 2021

Quantum key distribution (QKD) is a technology that allows secure key exchange between two distant users. A widespread adoption of QKD requires the development of simple, low-cost, and stable systems. However, implementation of the current QKD requires a complex self-alignment process during the initial stage and an additional hardware to compensate the environmental disturbances. In this study, we present the implementation of a simple QKD with the help of a stable transmitter-receiver scheme, which simplifies the self-alignment and is robust enough to withstand environmental disturbances. In case of the stability test, the implementation system is able to remain stable for 48 h and exhibits an average quantum bit error rate of less than 1% without any feedback control. The scheme is also tested over a fiber spool, obtaining a stable and secure finite key rate of 7.32k bits per second over a fiber spool extending up to 75 km. The demonstrated long-term stability and obtained secure key rate prove that our method of implementation is a promising alternative for practical QKD systems, in particular, for CubeSat platform and satellite applications.
Axial line-scanning stimulated emission depletion fluorescence correlation spectroscopy
Authors: Gao Peng , Nienhaus G. Ulrich 
Published: April 2021

Investigating the dynamics and interactions of biomolecules within or attached to membranes of living cells is crucial for understanding biology at the molecular level. In this pursuit, classical, diffraction-limited optical fluorescence microscopy is widely used, but it faces limitations due to (1) the heterogeneity of biomembranes on the nanoscale and (2) the intrinsic motion of membranes with respect to the focus. Here we introduce a new confocal microscopy-based fluctuation spectroscopy technique aimed at alleviating these two problems, called axial line-scanning stimulated emission depletion fluorescence correlation spectroscopy (axial ls-STED-FCS). Axial line scanning by means of a tunable acoustic gradient index of refraction lens provides a time resolution of a few microseconds, which is more than two orders of magnitude greater than that of conventional, lateral line-scanning fluorescence correlation spectroscopy (typically around 1 ms). Using STED excitation, the observation area on the membrane can be reduced 10–100 fold, resulting in sub-diffraction spatial resolution and the ability to study samples with densely labeled membranes. Due to these attractive properties, we expect that the axial ls-STED-FCS will find wide application, especially in the biomolecular sciences.
Full wafer scale electroluminescence properties of AlGaN-based deep ultraviolet LEDs with different well widths
Authors: Zhang Yi , Zhang Shuang , Xu Linlin , Zhang Huixue , Wang Ange , Shan Maocheng , Zheng Zhihua , Wang Hao , Wu Feng , Dai Jiangnan , Chen Changqing 
Published: April 2021

Deep ultraviolet (DUV) LEDs have great potential in sterilization, water, air purification, and other fields. In this work, DUV LED wafers with different quantum well (QW) widths were grown by metal–organic chemical vapor deposition. It is found that the light output power (LOP) and peak wavelength of all chips are not only related to the QW thickness but also affected by warpage. For the first time, to the best of our knowledge, a positive correlation between the LOP and peak wavelength of DUV LED chips on the same wafer was observed, which is very important for improving the yield of DUV LEDs and reducing costs. Furthermore, the influence of QW thickness on the external quantum efficiency (EQE) of DUV LED has also been investigated. As the thickness of the QW increases, the exciton localization effect decreases and the quantum confinement Stark effect increases. Consequently, DUV LED wafers with a QW thickness of 2 nm have the highest EQE and yield. These findings not only help to improve the efficiency of DUV LEDs but also provide new insights for evaluating the performance of DUV LED wafers.
High-performance quantum-dot distributed feedback laser on silicon for high-speed modulations
Authors: Liang Di , Srinivasan Sudharsanan , Descos Antoine , Zhang Chong , Kurczveil Geza , Huang Zhihong , Beausoleil Raymond 
Published: April 2021

We report a 1310 nm heterogeneous quantum-dot distributed feedback laser on silicon with high efficiency and modulation capability and demonstrate isolator-free external modulation at 25 Gb/s using a metal-oxide semiconductor capacitor microring modulator.
Choice of CTO scores to predict procedural success in clinical practice. A comparison of 4 different CTO PCI scores in a comprehensive national registry including expert and learning CTO operators
Authors: Salinas Pablo , Gonzalo Nieves , Moreno Víctor H. , Fuentes Manuel , Santos-Martinez Sandra , Fernandez-Diaz José Antonio , Amat-Santos Ignacio J. , Ojeda Francisco Bosa , Borrego Juan Caballero , Cuesta Javier , Hernández José María de la Torre , Diego-Nieto Alejandro , Dubois Daniela , Galeote Guillermo , Goicolea Javier , Gutiérrez Alejandro , Jiménez-Fernández Miriam , Jiménez-Mazuecos Jesús , Jurado Alfonso , Lacunza Javier , Lee Dae-Hyun , López María , Lozano Fernando , Martin-Moreiras Javier , Martin-Yuste Victoria , Millán Raúl , Miñana Gema , Mohandes Mohsen , Morales-Ponce Francisco J. , Núñez Julio , Ojeda Soledad , Pan Manuel , Rivero Fernando , Robles Javier , Rodríguez-Leiras Sergio , Rojas Sergio , Rondán Juan , Rumiz Eva , Sabaté Manel , Sanchís Juan , Vaquerizo Beatriz , Escaned Javier 
Published: April 2021

Background
We aimed to compare the performance of the recent CASTLE score to J-CTO, CL and PROGRESS CTO scores in a comprehensive database of percutaneous coronary intervention of chronic total occlusion procedures.

Methods
Scores were calculated using raw data from 1,342 chronic total occlusion procedures included in REBECO Registry that includes learning and expert operators. Calibration, discrimination and reclassification were evaluated and compared.

Results
Mean score values were: CASTLE 1.60±1.10, J-CTO 2.15±1.24, PROGRESS 1.68±0.94 and CL 2.52±1.52 points. The overall percutaneous coronary intervention success rate was 77.8%. Calibration was good for CASTLE and CL, but not for J-CTO or PROGRESS scores. Discrimination: the area under the curve (AUC) of CASTLE (0.633) was significantly higher than PROGRESS (0.557) and similar to J-CTO (0.628) and CL (0.652). Reclassification: CASTLE, as assessed by integrated discrimination improvement, was superior to PROGRESS (integrated discrimination improvement +0.036, p<0.001), similar to J-CTO and slightly inferior to CL score (– 0.011, p = 0.004). Regarding net reclassification improvement, CASTLE reclassified better than PROGRESS (overall continuous net reclassification improvement 0.379, p<0.001) in roughly 20% of cases.

Conclusion
Procedural percutaneous coronary intervention difficulty is not consistently depicted by available chronic total occlusion scores and is influenced by the characteristics of each chronic total occlusion cohort. In our study population, including expert and learning operators, the CASTLE score had slightly better overall performance along with CL score. However, we found only intermediate performance in the c-statistic predicting chronic total occlusion success among all scores.
Plasma pentosidine levels are associated with prevalent fractures in patients with chronic liver disease
Authors: Saeki Chisato , Saito Mitsuru , Kanai Tomoya , Nakano Masanori , Oikawa Tsunekazu , Torisu Yuichi , Saruta Masayuki , Tsubota Akihito 
Published: April 2021

Aim
Osteoporotic fractures negatively impact health-related quality of life and prognosis. Advanced glycation end products (AGEs) impair bone quality and reduce bone strength. The aim of this study was to determine the relationship between plasma levels of pentosidine, a surrogate marker for AGEs, and prevalent fractures in patients with chronic liver disease (CLD).

Methods
This cross-sectional study included 324 patients with CLD. Vertebral fractures were evaluated using lateral thoracolumbar spine radiographs. Information on prevalent fractures was obtained through a medical interview, medical records, and/or radiography. The patients were classified into low (L), intermediate (I), and high (H) pentosidine (Pen) groups based on baseline plasma pentosidine levels.

Results
Of the 324 patients, 105 (32.4%) had prevalent fractures. The prevalence of liver cirrhosis (LC) and prevalent fractures significantly increased stepwise with elevated pentosidine levels. The H-Pen group had the highest prevalence of LC (88.6%, p < 0.001) and prevalent fractures (44.3%, p = 0.007), whereas the L-Pen group had the lowest prevalence of LC (32.1%, p < 0.001) and prevalent fractures (21.0%, p = 0.007). Multiple logistic regression analysis identified pentosidine as a significant independent factor related to prevalent fractures (odds ratio = 1.069, p < 0.001). Pentosidine levels increased stepwise and correlated with liver disease severity. They were markedly high in patients with decompensated LC. In multiple regression analysis, liver functional reserve factors (total bilirubin, albumin, and prothrombin time-international normalized ratio) significantly and independently correlated with pentosidine levels.

Conclusions
Plasma pentosidine was significantly associated with prevalent fractures and liver functional reserve in patients with CLD. Pentosidine may be useful in predicting fracture risk and should be closely followed in CLD patients with advanced disease.
Notes from the Editors, April 2021
Authors: Editors - 
Published: April 2021

buy this issue
Many factors are involved in COVID-19 mortality rates. Nevertheless, it is clear that the more socialist-oriented countries—by prioritizing social needs and public health, plus aggressive testing, tracing, and enlisting the aid of their populations—have generally been more effective in limiting the effects of the disease on their societies. The failure of the wealthier capitalist countries to do so is largely a result of their prioritization of profits over people.
Global competition of an organization: Managerial analysis of IBM’s global operations under the concepts - value chain, value network and value shop
Authors: Kwadade-Cudjoe Francis 
Published: April 2021

Globalization has been one of the strategies many organizations looking to achieve competitive advantage in their markets of operation have been implementing. It has been in existence since the Europeans and Americans started to move into other continents to conquer nations within those continents. Globalization involves the movement of an organization to other parts of the globe in order to utilize the opportunities normally available in those countries for manufacturing of products and trading. There are many strategies through which organizations could use to go global. However the most popular strategies are alliances, acquisitions, mergers and joint ventures. Most organizations which go global usually look for how they could cut cost by utilizing the cheaper natural and human resources available in those countries for production of goods and services. These organizations which go global are called multi-national companies (MNCs), as they usually have assets in the countries they operate from. Some organizations have been able to benefit substantially from globalization, whilst others not. The successful organizations have been able to achieve competitive advantage and some of them have even been able to attain sustained competitive advantage in their fields of operation.
Ameen F. Rihani's 'Biophilic Masculinity' in The Heart of Lebanon and The Rihani Essays
Authors: Karam Savo 
Published: April 2021

Now that we have reached the third millennium, an era associated with the onslaught of modernity, technology, industrialization and urbanization, it is time for our relationship with nature to undergo an ecological evolution through which a conservationist masculinity can develop. In this respect, it is particularly essential that literature provide a genuine modernized perspective, a biocentric understanding oriented towards a biophilic attachment to nature that centers on the affirmation of universal kinship based on the connection to all organic life. The cornerstone of the biophilia notion is a balanced
man-nature relationship which is still undervalued in the realm of green literature. In this perspective, it is worth highlighting Ameen Fares Rihani’s edifying contribution to the realm of deep ecology. The works of this Lebanese-American writer and thinker have not been given sufficient attention when his prosaic oeuvre effectively reflects man’s regrettable alienation from the natural environment. In a sense, Rihani’s prose with its biophilic inclination is a crucial addition to the body of works concerned with restoring the gap between nature and mankind. This paper, therefore, attempts to study Rihani's approach to living nature from the perspective of evolutionary biology by shedding light on an unexplored aspect, namely his essentially biophilic conviction evident in his landmark book Qualb Lubnan (The Heart of Lebanon) and in Ar-Rihaniyyaat (The Rihani Essays). These works will be analyzed from a literary ecocritical perspective and against ecological masculinity which is the most recent interpretive paradigm of ecocriticism. This reading will also profess that Rihani's intention is to ecologize modern masculinity, Eastern and/or Western masculine thought, through re-designing an alternative future, a deep green future founded upon the biophilia hypothesis.
Title: Intimate Partner Violence: The Moderating Role of Personality Trait and Religion.
Authors: Isangha Stanley Oloji , Ngwu Christopher Ndubuisi , Iwuagwu Anthony Obinna , Abonyi Sunday Evaristus , Nnaji Akuchukwu Oprah , Rahman Farah Naz 
Published: April 2021

Objective: Intimate partner violence which is an aspect of family violence has most often than not affected peaceful family growth across the world, while it is largely portrayed that men are the sole perpetrators of IPV and women its victims. Statistics across countries in America, Asia, Europe and Africa have shown men to be victims as well, both in heterosexual and homosexual family, thus IPV can be perpetrated by both sexes just as they can also be victims. This study therefore assessed the moderating role of personality trait and religion on intimate partner violence in heterosexual relationship.
Methods: Using a mixed method, 384 residents of Uyo metropolis were surveyed and 10 in-depth interviews was conducted among Psychology and Sociology lecturers from the University of Uyo Akwa Ibom state. The big five factor model served as its theoretical orientation. The big five personality inventory, religious orientation test and intimate partner violence propensity scale were used in generating data. Data were analyzed using SPSS version 20 software. Chi square test was used to test relationships while their long-run influence was ascertained using multiple and binary logistics linear regression analysis.
Result: Findings show that majority of the respondents have abused their partners physically or psychologically. Findings show personality traits and religion as independent and joint predictors of intimate partner violence.
Conclusion: It is recommended that clinicians, psychiatrists among other related professionals should always consider personality traits and religion when dealing with issues on IPV.
Retinal Pigment Epithelium and Neural Retinal Progenitors Interact via Semaphorin 6D to Facilitate Optic Cup Morphogenesis
Authors: Cechmanek Paula Bernice , Hehr Carrie Lynn , McFarlane Sarah 
Published: April 2021

AbstractCell movement propels embryonic tissues to acquire shapes required for mature function. The movements are driven both by acto-myosin signaling and by cells interacting with the extracellular matrix (ECM). Unknown is whether cell-cell interactions within a tissue are also required, and the molecular mechanisms by which such communication might occur. Here, we use the developing visual system of zebrafish as a model to understand the role cell-cell communication plays in tissue morphogenesis in the embryonic nervous system. We identify that cell-cell-mediated contact between two distinct cell populations, progenitors of the neural retina and retinal pigment epithelium (RPE), facilitates epithelial flow to produce the mature cupped retina. We identify for the first time the need in eye morphogenesis for distinct populations of progenitors to interact, and suggest a novel role for a member of a key developmental signaling family, the transmembrane Semaphorin6d, as mediating communication between distinct cell types to control tissue morphogenesis.
“The Very Music of the Name”
Authors: Townsend Chris 
Published: April 2021

Chris Townsend, “‘The Very Music of the Name’: Uncertainty as Aesthetic Principle in Keats’s Endymion” (pp. 441–472)
It is well known that John Keats thought that true poets were those who are capable of being in “uncertainties, Mysteries, doubts” without feeling the need to reach after solid facts. And “uncertainty” is a recurrent term in his 1818 poem Endymion and its preface. But what does it mean for the figure of Endymion to follow an “uncertain path,” and what role do experimental poetics play in that experience of not knowing? This essay reflects on three aspects of the rhythms of Endymion—the relation of line to sentence, the transformative quality of the poem’s rhymes, and the rhythmical malleability of the name “Endymion” itself—to argue that what Keats’s early critics were hostile to in his poem was precisely what he strove to produce: a poetics of uncertainty. By turning close attention to the local effects of Keats’s rhythms, and by mounting an argument about the structure of his thinking that concerns the shape of his verses, I also want to reopen a perennial question in both Formalist and New Historicist branches of Keats scholarship: whether it makes sense to think of Keats as a “political” or “ideological” poet, and of what that might mean in relation to his aesthetics.