bluuebunny/crossref_metadata_2025_split huggingface dataset:
Desarrollo tecnológico para mejorar la competitividad a productores de la Lechuguilla en la Comunidad la Buena Cardonal, Hidalgo.
Authors: Maldonado Sánchez Marisol , Martínez Martin Gloria 
Published: October 2021

El presente trabajo contiene el proceso del desarrollo tecnológico que se realizó para productos hechos a base de lechuguilla de la comunidad la Buena, Municipio de Cardonal con el objetivo de crear un nuevo método al abrir un nuevo mercado y hacer frente a desempleo y a la falta de economía familiar que prevalece, según la secretaria de economía existe una parte significativa de personas desempleadas en el estado de Hidalgo, punto que nos ha llevado a atender como Universidad a uno de los problemas del País y del Estado de Hidalgo. El desarrollo tecnológico contribuye en la localidad para elevar las cifras de gente ocupada a través de los oficios. Se realizó una investigación aplicada con 25 productores de lechuguilla entre 5 a 20 años en el oficio, la investigación fue trasversal porque se diseñó un instrumentos con 15 reactivos, fue exploratoria porque se muestran datos del objeto de estudio, y descriptiva porque indica las características de los productores que dio origen al desarrollo de una plataforma web que alojará un catálogo de los diferentes productos de lechuguilla usando herramientas tecnológicas como es el caso de HTML para la plataforma web y un manejador de base de datos MySQL. Para la creación de la base de datos.
The present work contains the technological development process that was carried out for products made from lechuguilla from the Buena community, Municipality of Cardonal with the aim of creating a new method when opening a new market and facing unemployment and the lack of Family economy that prevails, according to the secretary of economy there is a significant part of unemployed people in the state of Hidalgo, a point that has led us to serve as a university to one of the problems of the country and the state of Hidalgo. The technological development contributes in the locality to raise the numbers of people occupied through the offices. An applied research was carried out with 25 producers of lechuguilla with 20 years in the trade, the research was transversal because an instrument with 15 reagents was designed, it was exploratory because it shows data of the object of study, and descriptive because it indicates the characteristics of the producers Which gave rise to the development of a web platform that will host a catalog of the different products of lechuguilla using technological tools such as HTML for the web platform and a MySQL database manager. For the creation of the database.
Estudio de seguimiento de egresados como herramienta para la actualización curricular con fines de acreditación de cuatro licenciaturas
Authors: Méndez Torres R. , Sánchez Valencia Ma. R. 
Published: October 2021

El presente trabajo muestra el análisis comparativo de cohorte transversal que resulta del estudio de seguimiento de egresados para la generación 2013 de la Universidad Interactiva y a Distancia del Estado de Guanajuato (UNIDEG). La intención es realizar una actualización curricular que eventualmente permita la acreditación por parte de los organismos de COPAES de cuatro licenciaturas. Se parte de la hipótesis de que no existe diferencia significativa en los resultados y opiniones de los egresados de las diferentes carreras. Los resultados permiten conocer información relevante de los egresados que generan el autoconocimiento de la institución y la puesta en marcha de acciones de mejoramiento de la calidad académica y al mismo tiempo el acercamiento a los egresados para impulsar proyectos en los que se les involucre.
This paper shows a cross sectional analysis of a graduates follow up study of 2013 generation of Universidad Interactiva y a Distancia del Estado de Guanajuato (UNIDEG). The purpose is to make a curricular update that eventually allow the accreditation by of the four bachelors by the members of COPAES. The initial hypothesis is that there is no significant difference in the results and opinions of graduates of different bachelors. The results let to know relevant information from graduates that generate self-knowledge of the institution to generate actions to improve academic quality while approaching graduates to promote projects in which they are involved.
Role of Feedback and Negotiation in Interlanguage Development
Authors: Shahid Shama-E 
Published: October 2021

A central theme in second language acquisition is Interlanguage, an idea grounded on the concept that the human brain activates an innate psychological structure in a second language learning process. It is a system that is constructed by second language learners. There is a distinct language system in second language learners’ utterances which is quite different from the native speakers (Selinker 1972, p. 209-241). Interlanguage varies under diverse contexts, e.g., one domain of IL can be different from another one in terms of fluency, accuracy, and complexity. However, interlanguage can cease developing or fossilize, in any of its developmental stages due to the complexities a learner faces in acquiring a second language. According to Mitchell et al. (2013, p.60), under the platform of interaction, feedback, modified input, negotiation for meaning, and modified input come together to facilitate second language acquisition. It is evident from this point that Feedback and Negotiation are interrelated. This paper proposes to discuss these two subjects under the umbrella term interaction and argues the role of both of them on interlanguage development, concluding with an analysis of these techniques and the pedagogical implications.
Vitamin D Analogs Can Retard the Onset or Progression of Diabetic Kidney Disease: A Systematic Review
Authors: Uwaezuoke Samuel N. 
Published: October 2021

IntroductionPrevious studies have shown that vitamin D analogs (such as paricalcitol) can reduce albuminuria in patients with diabetes mellitus and retard the progression of diabetic kidney disease (DKD). A recent systematic review reported significant improvement of renal function in patients with DKD who received vitamin D or its analogs. Study-driven data about their use in improving DKD outcomes have continued to accumulate over the years.AimThis paper aims to systematically review the contemporary evidence about the effectiveness of vitamin D analogs in retarding the onset or progression of DKD.MethodsWith appropriate descriptors, two electronic databases (PubMed and Google Scholar) were searched for articles published between 2015 and 2021 in the English language. Primary studies that fulfilled the inclusion criteria were selected; their titles and abstracts were screened, and duplicates were removed. Relevant data were retrieved from the final selected studies using a preconceived data-extraction form.ResultsA total of eight studies (three randomized-controlled trials, one prospective study, and four cross-sectional studies) were reviewed. A total of 6,243 participants were investigated in the eight studies and comprised young adults, middle-aged adults, and the elderly with a male-gender predominance. One randomized controlled trial reported that paricalcitol significantly improved renal function in type 1 diabetes patients with renal impairment when combined with renin-angiotensin-aldosterone system (RAAS) blockers. A strong correlation between vitamin D deficiency and DKD risk was noted in the majority of the cross-sectional studies. High doses of cholecalciferol (4,000 or 10,000 IU/day), given early in DKD, significantly reduced disease prevalence.ConclusionParicalcitol may retard the onset or progression of DKD, especially if administered in combination with RAAS blockers. The association of vitamin D deficiency with DKD risk also supports this therapeutic effect. Future systematic reviews are still needed to strengthen the current evidence on therapeutic benefit of vitamin D or its analogs in DKD.
Metal-Free Heptazine-Based Porous Polymeric Network as Highly Efficient Catalyst for CO2 Capture and Conversion
Authors: Sharma Neha , Ugale Bharat , Kumar Sunil , Kailasam Kamalakannan 
Published: October 2021

The capture and catalytic conversion of CO2 into value-added chemicals is a promising and sustainable approach to tackle the global warming and energy crisis. The nitrogen-rich porous organic polymers are excellent materials for CO2 capture and separation. Herein, we present a nitrogen-rich heptazine-based microporous polymer for the cycloaddition reaction of CO2 with epoxides in the absence of metals and solvents. HMP-TAPA, being rich in the nitrogen site, showed a high CO2 uptake of 106.7 mg/g with an IAST selectivity of 30.79 toward CO2 over N2. Furthermore, HMP-TAPA showed high chemical and water stability without loss of any structural integrity. Besides CO2 sorption, the catalytic activity of HMP-TAPA was checked for the cycloaddition of CO2 and terminal epoxides, resulting in cyclic carbonate with high conversion (98%). They showed remarkable recyclability up to 5 cycles without loss of activity. Overall, this study represents a rare demonstration of the rational design of POPs (HMP-TAPA) for multiple applications.
Incremental Value of Left Ventricular Mechanical Dyssynchrony Assessment by Nitrogen-13 Ammonia ECG-Gated PET in Patients With Coronary Artery Disease
Authors: Zheng Danzha , Liu Yanyun , Zhang Lei , Hu Fan , Tan Xubo , Jiang Dawei , Zhou Weihua , Lan Xiaoli , Qin Chunxia 
Published: October 2021

Background: Phase analysis is a technique used to assess left ventricular mechanical dyssynchrony (LVMD) in nuclear myocardial imaging. Previous studies have found an association between LVMD and myocardial ischemia. We aim to assess the potential diagnostic value of LVMD in terms of myocardial viability, and ability to predict major adverse cardiac events (MACE), using Nitrogen-13 ammonia ECG-gated positron emission tomography (gPET).Methods: Patients with coronary artery disease (CAD) who underwent Nitrogen-13 ammonia and Fluorine-18 FDG myocardial gPET were enrolled, and their gPET imaging data were retrospectively analyzed. Patients were followed up and major adverse cardiac events (MACE) were recorded. The Kruskal-Wallis test and Mann-Whitney U test were performed to compare LVMD parameters among the groups. Binary logistic regression analysis, receiver operating characteristic (ROC) curve analysis, and multiple stepwise analysis curves were applied to identify the relationship between LVMD parameters and myocardial viability. Kaplan–Meier survival curves and the log-rank test were used to look for differences in the incidence of MACE.Results: In total, 79 patients were enrolled and divided into three groups: Group 1 (patients with only viable myocardium, n = 7), Group 2 (patients with more viable myocardium than scar, n = 33), and Group 3 (patients with less viable myocardium than scar, n = 39). All LVMD parameters were significantly different among groups. The median values of systolic phase standard deviation (PSD), systolic phase histogram bandwidth (PHB), diastolic PSD, and diastolic PHB between Group 1 and Group 3, and Group 2 and Group 3 were significantly different. A diastolic PHB of 204.5° was the best cut-off value to predict the presence of myocardial scar. In multiple stepwise analysis models, diastolic PSD, ischemic extent, and New York Heart Association (NYHA) classification were independent predictive factors of viable myocardium and myocardial scar. The incidence of MACE in patients with diastolic PHB &gt; 204.5° was 25.0%, higher than patients with diastolic PHB &lt;204.5° (11.8%), but the difference was not significant.Conclusions: LVMD generated from Nitrogen-13 ammonia ECG-gated myocardial perfusion imaging had added diagnostic value for myocardial viability assessment in CAD patients. LVMD did not show a definite prognostic value.
Reappraisal of Non-vitamin K Antagonist Oral Anticoagulants in Atrial Fibrillation Patients: A Systematic Review and Meta-Analysis
Authors: Liu Fuwei , Yang Yunyao , Cheng Winglam , Ma Jianyong , Zhu Wengen 
Published: October 2021

Background: Recent observational studies have compared effectiveness and safety profiles between non-vitamin K antagonist oral anticoagulants (NOACs) and warfarin in patients with atrial fibrillation (AF). Nevertheless, the confounders may exist due to the nature of clinical practice-based data, thus potentially influencing the reliability of results. This systematic review and meta-analysis were conducted to compare the effect of NOACs with warfarin based on the propensity score-based observational studies vs. randomized clinical trials (RCTs).Methods: Articles included were systematically searched from the PubMed and EMBASE databases until March 2021 to obtain relevant studies. The primary outcomes were stroke or systemic embolism (SSE) and major bleeding. Hazard ratios (HRs) and 95% confidence intervals (CIs) of the outcomes were extracted and then pooled by the random-effects model.Results: A total of 20 propensity score-based observational studies and 4 RCTs were included. Compared with warfarin, dabigatran (HR, 0.82 [95% CI, 0.71–0.96]), rivaroxaban (HR, 0.80 [95% CI, 0.75–0.85]), apixaban (HR, 0.75 [95% CI, 0.65–0.86]), and edoxaban (HR, 0.71 [95% CI, 0.60–0.83]) were associated with a reduced risk of stroke or systemic embolism, whereas dabigatran (HR, 0.76 [95% CI, 0.65–0.87]), apixaban (HR, 0.61 [95% CI, 0.56–0.67]), and edoxaban (HR, 0.58 [95% CI, 0.45–0.74]) but not rivaroxaban (HR, 0.92 [95% CI, 0.84–1.00]) were significantly associated with a decreased risk of major bleeding based on the observational studies. Furthermore, the risk of major bleeding with dabigatran 150 mg was significantly lower in observational studies than that in the RE-LY trial, whereas the pooled results of observational studies were similar to the data from the corresponding RCTs in other comparisons.Conclusion: Data from propensity score-based observational studies and NOAC trials consistently suggest that the use of four individual NOACs is non-inferior to warfarin for stroke prevention in AF patients.
Bulk Crustal Properties and Layered Velocity Structure in Fujian, SE China: Constraints From P and S Receiver Functions
Authors: Goyal Ayush , Hung Shu-Huei 
Published: October 2021

Multiple tectonic events since the Neoproterozoic era have framed the present-day lithosphere in the Fujian province affiliated with the eastern part of the South China Block. Comprehensive information of the crustal structure and bulk properties can aid to understand the geological features and tectonic processes of still much debate in this region. An attempt is made in this study to explore crustal thickness and internal velocities across Fujian using the teleseismic receiver functions (RFs). The H-V stacking of joint P and S RFs improves to simultaneously estimate crustal thickness, average Vp and Vs, and derived Vp/Vs ratio and bulk sound speed in three backazimuth sectors for each of 17 stations. Furthermore, a Neighborhood Algorithm nonlinear inversion of P RFs is employed to determine the layered structures of Vs and Vp/Vs beneath all the stations. Results indicate the crustal thickness varies from at most ∼35 km in northwest Fujian to 30–35 km in the inland mountains and 27–30 km in the southeastern coasts. The inferred Moho geometry is nonplanar or inclined across the Zhenghe-Dapu (ZD) and Changle-Zhaoan (CZ) fault zones, especially in the southern ZD fault area. The average Vp/Vs suggests that the crust is predominantly felsic in the Wuyi-Yunkai orogen and intermediate-to-mafic in the Cretaceous magmatic and metamorphic zones. A high-velocity upper crust along the coastline is revealed, which attributes to the Pingtan-Dongshan metamorphic belt. At the sites near the ZD fault zone, the intracrustal negative discontinuity occurs at a shallower depth of ∼15 km marking an abrupt Vs decrease into the low-velocity mid-to-lower crustal layer, probably linked to the closed paleo-rift basin remnants. The lower crust across the Fujian is generally characterized by relatively lower Vs and higher Vp/Vs (1.80–1.84) consistent with those of the mafic-ultramafic rocks, which do not support the proposed extensive magmatic underplating in the Late Mesozoic.
Risk Factors and a Prediction Model of Lateral Lymph Node Metastasis in CN0 Papillary Thyroid Carcinoma Patients With 1–2 Central Lymph Node Metastases
Authors: Wang Yuanyuan , Deng Chang , Shu Xiujie , Yu Ping , Wang Huaqiang , Su Xinliang , Tan Jinxiang 
Published: October 2021

BackgroundPapillary thyroid cancer (PTC) in clinically lymph node-negative (cN0) patients is prone toward lymph node metastasis. As a risk factor for tumor persistence and local recurrence, lateral lymph node metastasis (LLNM) is related to the number of central lymph node metastases (CLNMs).MethodsWe performed LLNM risk stratification based on the number of CLNMs for cN0 PTC patients who underwent thyroidectomy and lymph node dissection between January 2013 and December 2018. A retrospective analysis was applied to the 274 collected patients with 1-2 CLNMs. We examined the clinicopathological characteristics of the patients and constructed a LASSO model.ResultsIn the 1–2 CLNM group, tumors &gt;10 mm located in the upper region and nodular goiters were independent risk factors for LLNM. Specifically, tumors &gt;20 mm and located in the upper region contributed to metastasis risk at level II. Hashimoto’s thyroiditis reduced this risk (p = 0.045, OR = 0.280). Age ≤ 30 years and calcification (microcalcification within thyroid nodules) correlated with LLNM. The LASSO model divided the population into low- (25.74%) and high-risk (57.25%) groups for LLNM, with an AUC of 0.715.ConclusionsFor patients with 1–2 CLNMs, young age, calcification, nodular goiter, tumor &gt;10 mm, and tumor in the upper region should alert clinicians to considering a higher occult LLNM burden. Close follow-up and therapy adjustment may be warranted for high-risk patients.
A Multi-Tracer Study of Fresh Water Sources for a Temperate Urbanized Coastal Bay (Southern Baltic Sea)
Authors: von Ahn Cátia Milene Ehlert , Scholten Jan C. , Malik Christoph , Feldens Peter , Liu Bo , Dellwig Olaf , Jenner Anna-Kathrina , Papenmeier Svenja , Schmiedinger Iris , Zeller Mary A. , Böttcher Michael Ernst 
Published: October 2021

Terrestrial surface waters and submarine ground water discharge (SGD) act as a source of dissolved substances for coastal systems. Solute fluxes of SGD depend on the ground water composition and the water-solid-microbe interactions close to the sediment-water interface. Thus, this study aims to characterize and evaluate the hydrogeochemical gradients developing in the fresh-salt water mixing zone of the Wismar Bay (WB), southern Baltic Sea, Germany. Sampling campaigns covering the WB, the fresh-salt water mixing zone at the beach of the WB shoreline, terrestrial surface and ground waters near the WB as well sediments pore water were carried out. In these different waters, the distribution of dissolved inorganic carbon, nutrients, major ions, trace elements, stable isotopes (H, O, C, S), and radium isotopes have been investigated. Enhanced concentrations of radium isotopes together with dissolved manganese, barium in the surface waters of the eastern WB indicated benthic-pelagic coupling via the exchange between pore water and the water column. Salinity, stable isotopes, and major ions in sediment pore water profiles identified the presence of fresh ground water below about 40 cmbsf in the central part of the bay. Geophysical acoustic techniques revealed the local impact of anthropogenic sediment excavation, which reduced the thickness of a sediment layer between the coastal aquifer and the bottom water, causing, therefore, a ground water upward flow close to the top sediments. The fresh impacted pore water stable isotope composition (δ18O, δ2H) plot close to the regional meteoric water line indicating a relatively modern ground water source. The calculated organic matter mineralization rates and the dissolved inorganic carbon sediment-water fluxes were much higher at the fresh impacted site when compared to other unimpacted sediments. Therefore, this study reveals that different fresh water sources contribute to the water balance of WB including a SGD source.
Comparison of Neighborhood-Scale, Residential Property Flood-Loss Assessment Methodologies
Authors: Mostafiz Rubayet Bin , Friedland Carol J. , Rahman Md Asif , Rohli Robert V. , Tate Eric , Bushra Nazla , Taghinezhad Arash 
Published: October 2021

Leading flood loss estimation models include Federal Emergency Management Agency’s (FEMA’s) Hazus, FEMA’s Flood Assessment Structure Tool (FAST), and (U.S.) Hydrologic Engineering Center’s Flood Impact Analysis (HEC-FIA), with each requiring different data input. No research to date has compared the resulting outcomes from such models at a neighborhood scale. This research examines the building and content loss estimates by Hazus Level 2, FAST, and HEC-FIA, over a levee-protected census block in Metairie, in Jefferson Parish, Louisiana. Building attribute data in National Structure Inventory (NSI) 2.0 are compared against “best available data” (BAD) collected at the individual building scale from Google Street View, Jefferson Parish building inventory, and 2019 National Building Cost Manual, to assess the sensitivity of input building inventory selection. Results suggest that use of BAD likely enhances flood loss estimation accuracy over existing reliance on default data in the software or from a national data set that generalizes over a broad scale. Although the three models give similar mean (median) building and content loss, Hazus Level 2 results diverge from those produced by FAST and HEC-FIA at the individual building level. A statistically significant difference in mean (median) building loss exists, but no significant difference is found in mean (median) content loss, between building inventory input (i.e., NSI 2.0 vs BAD), but both the building and content loss vary at the individual building scale due to difference in building-inventory-reported foundation height, foundation type, number of stories, replacement cost, and content cost. Moreover, building loss estimation also differs significantly by depth-damage function (DDF), for flood depths corresponding with the longest return periods, with content loss differing significantly by DDF at all return periods tested, from 10 to 500 years. Knowledge of the extent of estimated differences aids in understanding the degree of uncertainty in flood loss estimation. Much like the real estate industry uses comparable home values to appraise a home, flood loss planners should use multiple models to estimate flood-related losses. Moreover, results from this study can be used as a baseline for assessing losses from other hazards, thereby enhancing protection of human life and property.