bluuebunny/crossref_metadata_2025_split huggingface dataset:
Willingness to Work amongst Australian Frontline Healthcare Workers during Australia’s First Wave of Covid-19 Community Transmission: Results of an Online Survey
Authors: Hill Michella , Smith Erin , Mills Brennen 
Published: September 2021

Abstract

Objectives:
The majority of research investigating healthcare workers’ (HCWs) willingness to work during public health emergencies, asks participants to forecast their perceptions based on hypothetical emergencies, rather than in response to the actual public health emergencies they have experienced. This research explored frontline HCWs willingness to work during Australia’s first wave of the COVID-19 pandemic among frontline HCWs.

Methods:
Participants (n = 580) completed an online questionnaire regarding their willingness to work during the pandemic.

Results:
A total of 42% of participants reported being less willing to work during the pandemic compared to before. Availability of personal protective equipment (PPE), concern expressed by family members, and viral exposure were significant barriers. A third of participants disagreed that some level of occupational risk for exposure to infectious disease was acceptable while a quarter of participants had received communications from their workplace concerning obligations to work during COVID-19.

Conclusions:
The COVID-19 pandemic has impacted Australian frontline HCWs’ willingness to work. Scarcity of PPE and exposure to the virus were the most cited reasons impacting on willingness to work. Appropriate policies and practices should be implemented and communicated efficiently to frontline HCW’s. This research provides insight into the lived experiences of Australian healthcare professionals’ willingness to work during a pandemic.
Wood and bark lignin contents of trees from deciduous forests of eastern India
Authors: Deb Debal , Roy Priyabrata 
Published: September 2021

Abstract
Lignin is a polyphenolic compound found in plant tissues, especially wood and bark. The lignin content determines the quality of wood biochar in agroecological uses, and is used in the production of synthetic resins and adhesives. Despite its importance in plant physiology and its agricultural and industrial utility, there exists a wide gap of knowledge of lignin contents of tropical hardwood trees of South Asia, except for a few species. We present here the first estimation of lignin content in wood and bark of 48 species from tropical deciduous forests of India. We show that some species are characterized by greater wood lignin (WL) compared with bark lignin (BL) content, contrary to the generalization held for hardwood trees, and suggest a plausible correspondence between the WL to BL ratio and timber quality.
RETIRE WITH THANKS: RETHINKING LUCRETIUS 3.962
Authors: Takeshita Tetsufumi 
Published: September 2021

AbstractThis article aims at proposing a solution to one of the well-known textual cruces in Lucretius’ De rerum natura. After a brief survey of the suggested emendations, the author will shed some fresh light on Manning's gratus, which recent editors have curiously neglected. The idea that the old man should retire from life with thanks is not uncommon among classical writers. In addition, parallel expressions are also found in Epicurus’ own words. This article concludes that gratus is what we would expect in the last line of Nature's admonition in De rerum natura and, therefore, the most probable emendation.
The Río Grío–Pancrudo Fault Zone (central Iberian Chain, Spain): recent extensional activity revealed by drainage reversal
Authors: Peiro Alba , Simón José L. 
Published: September 2021

AbstractThe NNW–SSE-trending extensional Río Grío–Pancrudo Fault Zone is a large-scale structure that obliquely cuts the Neogene NW–SE Calatayud Basin. Its negative inversion during the Neogene–Quaternary extension gave rise to structural and geomorphological rearrangement of the basin margin. Geological mapping has allowed two right-relayed fault segments to be distinguished, whose recent extensional activity has been mainly characterized using a deformed planation surface (Fundamental Erosion Surface (FES) 3; 3.5 Ma) as a geomorphic marker. Normal slip along the Río Grío–Lanzuela Fault Segment has induced hanging-wall tilting, subsequent drainage reversal at the Güeimil valley after the Pliocene–Pleistocene transition, as well as morphological scarps and surficial ruptures in Pleistocene materials. In this sector, an offset of FES3 indicates a total throw ofc. 240 m, resulting in a slip rate of 0.07 mm a–1, while retrodeformation of hanging-wall tilting affecting a younger piedmont surface allows the calculation of a minimum throw in the range of 140–220 m after the Pliocene–Pleistocene transition, with a minimum slip rate of 0.07–0.11 mm a–1. For the late Pleistocene period, vertical displacement ofc. 20 m of a sedimentary level dated to 66.6 ± 6.5 ka yields a slip rate approaching 0.30–0.36 mm a–1. At the Cucalón–Pancrudo Fault Segment, the offset of FES3 allows the calculation of a maximum vertical slip of 300 m for the last 3.5 Ma, and hence a net slip rate close to 0.09 mm a–1. Totallingc. 88 km in length, the Río Grío–Pancrudo Fault Zone could be the largest recent macrostructure in the Iberian Chain, probably active, with the corresponding undeniable seismogenic potential.
Converbs in heritage Turkish: A contrastive approach
Authors: Iefremenko Kateryna , Schroeder Christoph , Kornfilt Jaklin 
Published: September 2021

AbstractTurkish expresses adverbial subordination predominantly by means of converb clauses. These are headed by nonfinite verbs, i.e. converbs, which have a converb suffix attached to the stem. The different converbs express different aspectual relations between the subordinate and the superordinate clause, and they can be modifying or non-modifying. We analyse data from speakers of Turkish as a heritage language in Germany and the U.S. as well as monolingual speakers of Turkish in Turkey. The data come from two age groups: adults and adolescents. We show that unlike in canonical Turkish, converbs in heritage Turkish can be multifunctional, meaning that they can express both simultaneity and causality, for example. Furthermore, we show that converbs in heritage Turkish can be both modifying and non-modifying. As possible factors which might be responsible for such variation, we discuss language contact, sociolinguistic differences between the speaker communities (Germany vs. the U.S.) and age of the speakers.
Role of saliva use during masturbation in the transmission of Chlamydia trachomatis in men who have sex with men
Authors: Xu Xianglong , Chow Eric P.F. , Regan David , Ong Jason J. , Gray Richard T. , Zhou Pingyu , Fairley Christopher K. , Zhang Lei 
Published: September 2021

Abstract
Masturbation is a common sexual practice in men, and saliva is often used as a lubricant during masturbation by men who have sex with men. However, the role of saliva use during masturbation in the transmission of chlamydia is still unclear. We developed population-level, susceptible-infected-susceptible compartmental models to explore the role of saliva use during masturbation on the transmission of chlamydia at multiple anatomical sites. In this study, we simulated both solo masturbation and mutual masturbation. Our baseline model did not include masturbation but included transmission routes (anal sex, oral-penile sex, rimming, kissing and sequential sexual practices) we have previously validated (model 1). We added masturbation to model 1 to develop the second model (model 2). We calibrated the model to five clinical datasets separately to assess the effects of masturbation on the prevalence of site-specific infection. The inclusion of masturbation (model 2) significantly worsened the ability of the models to replicate the prevalence of C. trachomatis. Using model 2 and the five data sets, we estimated that saliva use during masturbation was responsible for between 3.9% [95% confidence interval (CI) 2.0–6.8] and 6.2% (95% CI 3.8–10.5) of incident chlamydia cases at all sites. Our models suggest that saliva use during masturbation is unlikely to play a major role in chlamydia transmission between men, and even if it does have a role, about one in seven cases of urethral chlamydia might arise from masturbation.
Truncal valve leaflet reconstruction with autologous pericardium in a neonate
Authors: Ishidou Motonori , Ikai Akio , Sakamoto Kisaburo 
Published: September 2021

AbstractA boy diagnosed with persistent truncus arteriosus and severe truncal valve regurgitation had uncontrollable heart failure. Thus, truncal valve repair, ventricular septal defect closure, and right ventricular outflow tract reconstruction were performed on the second day of life. We report about a neonate with severe truncal valve regurgitation who was successfully treated with autologous pericardial truncal valve leaflet reconstruction.
‘An Amazing Want of Christianity’: Bishop Samuel Wilberforce and John Henry Newman’s Tense Relationship
Authors: Grosclaude Jérôme 
Published: September 2021

AbstractThis paper will examine the relationship between Samuel Wilberforce and John Henry Newman. The two priests had a common cause in their wish to see the Church of England rediscover its Catholic identity – which led them to work alongside one another at the beginning of the Oxford Movement – but quickly drifted apart because of their strong divergences on the nature of the Church and the place of Tradition, as well as Samuel Wilberforce’s strong hostility to Rome. The paper also examines the place of Samuel Wilberforce’s young brother in this relationship.
The People of God, Discipleship and Ministry in the Anglican Church Today and Tomorrow
Authors: Littleton John 
Published: September 2021

AbstractPeople of God is a well-known biblical term used to describe and understand the inclusive, holistic and serving nature of the Christian Church. Currently, members of the worldwide Anglican Communion are discussing discipleship and ministry. This paper explores the deep connection between describing the church as the People of God and the practice of discipleship and ministry. That exploration occurs through an examination of the considerable literature on the topic, and by discussing discipleship and ministry in light of understanding the church as the People of God. Discoveries made from the journey may surprise. Suggestions for church practice emerged with implications for: ecclesial language; parish ministry and mission; the processes of Anglican Diocesan Synods; and potential outcomes for the 2022 Lambeth Conference.
On the morphospace of eurypterine sea scorpions
Authors: BICKNELL Russell D. C. , AMATI Lisa 
Published: September 2021

ABSTRACTEurypterids (sea scorpions) are a group of extinct, marine euchelicerates that have an extensive Palaeozoic record. Despite lacking a biomineralised exoskeleton, eurypterids are abundantly preserved within select deposits. These collections make statistical analyses comparing the morphology of different genera possible. However, eurypterid shape has not yet been documented with modern geometric morphometric tools. Here, we summarise the previous statistical assessments of eurypterid morphology and expand this research by presenting landmark and semi-landmark analyses of 115 eurypterid specimens within the suborder Eurypterina. We illustrate that lateral compound eye morphology and position drives specimen placement in morphospace and separates proposed apex predators from more generalist forms. Additionally, evidence for size clusters inEurypterusthat may reflect ontogeny is uncovered. We highlight the use of geometric morphometric analyses in supporting the naming of new taxa and demonstrate that these shape data represent a novel means of understanding inter-generic ontogenetic trajectories and uncovering developmental changes within the diverse euarthropod group.
Two-Eyed Seeing and developmental origins of health and disease studies with indigenous partners
Authors: Liberda Eric N. , Zuk Aleksandra M. , Davey Roger , Edwards-Wheesk Ruby , Tsuji Leonard J. S. 
Published: September 2021

AbstractGlobally, mortality of Indigenous persons is greater than that of their non-Indigenous counterparts, which has been shown to be disproportionately attributable to non-communicable diseases. The historically subordinate position that Indigenous Knowledge (IK) held in comparison to Western science has shifted over the last several decades, with the credibility and importance of IK now being internationally recognized. Herein, we examine how Marsahall’s (2014) Two-Eyed Seeing can foster collaborative and culturally relevant Developmental Origins of Health and Disease (DOHaD) studies for health and well-being by using ‘..the best in Indigenous ways of knowing…[and] the best in Western (or mainstream) ways of knowing…and learn to use both these eyes for the benefit of all.’ At its core, Two-Eyed Seeing also includes the principles of ownership, control, access and possession, and Community-Based Participatory Research, which further reinforces the critical role of Indigenous peoples taking active roles in DOHaD research. Additionally, we also present a partnership model for working with Indigenous communities that includes the principles of respect, equity and empowerment. As researchers begin to fill the gap in Indigenous health, we outline how Two-Eyed Seeing should form the basis of DOHaD studies involving Indigenous communities. This model can be used to develop and guide projects that result in robust and meaningful participatory partnerships that have impactful uptake of research findings.
Optimizing chloroacetamide application timing in dicamba-resistant cotton production systems for control of glyphosate-resistant Palmer amaranth (Amaranthus palmeri)
Authors: Buol John T. , Franca Lucas X. , Dodds Darrin M. , Mills J. Anthony , DuBien Janice L. , Brown-Johnson Ashli E. , Shaw David R. , Reynolds Daniel B. 
Published: September 2021

Abstract
A chloroacetamide herbicide by application timing factorial experiment was conducted in 2017 and 2018 in Mississippi to investigate chloroacetamide use in a dicamba-based Palmer amaranth management program in cotton production. Herbicides used were S-metolachlor or acetochlor, and application timings were preemergence, preemergence followed by (fb) early postemergence, preemergence fb late postemergence, early postemergence alone, late postemergence alone, and early postemergence fb late postemergence. Dicamba was included in all preemergence applications, and dicamba plus glyphosate was included with all postemergence applications. Differences in cotton and weed response due to chloroacetamide type were minimal, and cotton injury at 14 d after late postemergence application was less than 10% for all application timings. Late-season weed control was reduced up to 30% and 53% if chloroacetamide application occurred preemergence or late postemergence only, respectively. Late-season weed densities were minimized if multiple applications were used instead of a single application. Cotton height was reduced by up to 23% if a single application was made late postemergence relative to other application timings. Chloroacetamide application at any timing except preemergence alone minimized late-season weed biomass. Yield was maximized by any treatment involving multiple applications or early postemergence alone, whereas applications preemergence or late postemergence alone resulted in up to 56% and 27% yield losses, respectively. While no yield loss was reported by delaying the first of sequential applications until early postemergence, forgoing a preemergence application is not advisable given the multiple factors that may delay timely postemergence applications such as inclement weather.
Response of broadleaf and grass cover crop species to soil residues of glyphosate and aminomethylphosphonic acid (AMPA)
Authors: Ganie Zahoor A. , Jhala Amit J. 
Published: September 2021

AbstractGlyphosate is the most widely used herbicide in the United States; however, concern is escalating about increasing residues of glyphosate and its metabolite aminomethylphosphonic acid (AMPA) in soil. There is a lack of scientific literature examining the response of cover crops to soil residues of glyphosate or AMPA. The objectives of this study were to evaluate the impact of glyphosate or AMPA residues in silty clay loam soil on emergence, growth, and biomass of cover crops, including cereal rye, crimson clover, field pea, hairy vetch, and winter wheat, as well as their germination in a 0.07% (0.7 g L–1) solution of AMPA or glyphosate. Greenhouse studies were conducted at the University of Nebraska–Lincoln to determine the dose response of broadleaf and grass cover crops to soil-applied glyphosate or AMPA. The results indicated that soil treated with glyphosate or AMPA up to 105 mg ae kg–1 of soil had no effect on the emergence, growth, above-ground biomass, and root biomass of any of the cover crop species tested. To evaluate the impact of AMPA or glyphosate on the seed germination of cover crop species, seeds were soaked in Petri plates filled with a 0.7 g L–1 solution of AMPA or glyphosate. There was no effect of AMPA on seed germination of any of the cover crop species tested. Seed germination of crimson clover and field pea in a 0.7 g L–1 solution of glyphosate was comparable to the nontreated control; however, the germination of cereal rye, hairy vetch, and winter wheat was reduced by 48%, 75%, and 66%, respectively, compared to the nontreated control. The results suggested that glyphosate or AMPA up to 105 mg ae kg–1 in silt clay loam soil is unlikely to cause any negative effect on the evaluated cover crop species.
The Microbiology of Metal Mine Waste: Bioremediation Applications and Implications for Planetary Health
Authors: Newsome Laura , Falagán Carmen 
Published: September 2021

AbstractMine wastes pollute the environment with metals and metalloids in toxic concentrations, causing problems for humans and wildlife. Microorganisms colonize and inhabit mine wastes, and can influence the environmental mobility of metals through metabolic activity, biogeochemical cycling and detoxification mechanisms. In this article we review the microbiology of the metals and metalloids most commonly associated with mine wastes: arsenic, cadmium, chromium, copper, lead, mercury, nickel and zinc. We discuss the molecular mechanisms by which bacteria, archaea, and fungi interact with contaminant metals and the consequences for metal fate in the environment, focusing on long‐term field studies of metal‐impacted mine wastes where possible. Metal contamination can decrease the efficiency of soil functioning and essential element cycling due to the need for microbes to expend energy to maintain and repair cells. However, microbial communities are able to tolerate and adapt to metal contamination, particularly when the contaminant metals are essential elements that are subject to homeostasis or have a close biochemical analog. Stimulating the development of microbially reducing conditions, for example in constructed wetlands, is beneficial for remediating many metals associated with mine wastes. It has been shown to be effective at low pH, circumneutral and high pH conditions in the laboratory and at pilot field‐scale. Further demonstration of this technology at full field‐scale is required, as is more research to optimize bioremediation and to investigate combined remediation strategies. Microbial activity has the potential to mitigate the impacts of metal mine wastes, and therefore lessen the impact of this pollution on planetary health.
Estimating Dispersion Coefficient in Flow Through Heterogeneous Porous Media by a Deep Convolutional Neural Network
Authors: Kamrava Serveh , Im Jinwoo , de Barros Felipe P. J. , Sahimi Muhammad 
Published: September 2021

AbstractEstimating the longitudinal dispersion coefficient in flow through heterogeneous porous media is paramount to many problems in geological formations. Moreover, although it is well‐known that is sensitive to the morphology of such formations, it has been very difficult to establish a firm link between the two. We describe a novel deep convolutional neural network (DCNN) for estimating . The inputs for training of the network are a large and diverse set of data consisting of three‐dimensional images of porous media, as well as their porosity, and the associated values computed by random‐walk particle‐tracking (RWPT) simulations. The trained network predicts very rapidly, and its predictions are in excellent agreement with the data not used in the training. Thus, a combination of the DCNN and RWPT simulation provides a powerful tool for studying many flow‐related phenomena in geological formations, and estimating their properties.
Intron retention-induced neoantigen load correlates with unfavorable prognosis in multiple myeloma
Authors: Dong Chuanpeng , Cesarano Annamaria , Bombaci Giuseppe , Reiter Jill L. , Yu Christina Y. , Wang Yue , Jiang Zhaoyang , Zaid Mohammad Abu , Huang Kun , Lu Xiongbin , Walker Brian A. , Perna Fabiana , Liu Yunlong 
Published: September 2021

AbstractNeoantigen peptides arising from genetic alterations may serve as targets for personalized cancer vaccines and as positive predictors of response to immune checkpoint therapy. Mutations in genes regulating RNA splicing are common in hematological malignancies leading to dysregulated splicing and intron retention (IR). In this study, we investigated IR as a potential source of tumor neoantigens in multiple myeloma (MM) patients and the relationship of IR-induced neoantigens (IR-neoAg) with clinical outcomes. MM-specific IR events were identified in RNA-sequencing data from the Multiple Myeloma Research Foundation CoMMpass study after removing IR events that also occurred in normal plasma cells. We quantified the IR-neoAg load by assessing IR-induced novel peptides that were predicted to bind to major histocompatibility complex (MHC) molecules. We found that high IR-neoAg load was associated with poor overall survival in both newly diagnosed and relapsed MM patients. Further analyses revealed that poor outcome in MM patients with high IR-neoAg load was associated with high expression levels of T-cell co-inhibitory molecules and elevated interferon signaling activity. We also found that MM cells exhibiting high IR levels had lower MHC-II protein abundance and treatment of MM cells with a spliceosome inhibitor resulted in increased MHC-I protein abundance. Our findings suggest that IR-neoAg may represent a novel biomarker of MM patient clinical outcome and further that targeting RNA splicing may serve as a potential therapeutic strategy to prevent MM immune escape and promote response to checkpoint blockade.
CloneSig can jointly infer intra-tumor heterogeneity and mutational signature activity in bulk tumor sequencing data
Authors: Abécassis Judith , Reyal Fabien , Vert Jean-Philippe 
Published: September 2021

AbstractSystematic DNA sequencing of cancer samples has highlighted the importance of two aspects of cancer genomics: intra-tumor heterogeneity (ITH) and mutational processes. These two aspects may not always be independent, as different mutational processes could be involved in different stages or regions of the tumor, but existing computational approaches to study them largely ignore this potential dependency. Here, we present CloneSig, a computational method to jointly infer ITH and mutational processes in a tumor from bulk-sequencing data. Extensive simulations show that CloneSig outperforms current methods for ITH inference and detection of mutational processes when the distribution of mutational signatures changes between clones. Applied to a large cohort of 8,951 tumors with whole-exome sequencing data from The Cancer Genome Atlas, and on a pan-cancer dataset of 2,632 whole-genome sequencing tumor samples from the Pan-Cancer Analysis of Whole Genomes initiative, CloneSig obtains results overall coherent with previous studies.