bluuebunny/crossref_metadata_2025_split huggingface dataset:
Time on the Market and Probability of Sale Using a Generalized Geometric Hazard Model
Authors: Caudill Steven B. , Bogosavljevic Ksenija , Johnson Ken H. , Mixon Franklin G. 
Published: April 2021

Abstract
This study makes two main contributions to the applied econometrics literature. First, it shows how the all-important marginal effects for time on the market and probability of sale can be obtained from any hazard model. Second, it extends the generalization of the geometric due to Gómez-Déniz, E. 2010. “Another Generalization of the Geometric Distribution.” Test 19: 399–415 to include covariates for use in the estimation of time on the market and probability of sale regressions in real estate, thus creating an entirely new hazard model based on probability of sale rather than time on the market. For the generalized geometric we develop expressions for the marginal effects (with approximate standard errors) for both the probability of sale and time on the market. This formulation allows the impact of changes in independent variables on both the probability of sale and time on the market to be determined from a single regression model. For comparison, we also obtain these two sets of marginal effects for the popular Weibull hazard model. The geometric, generalized geometric, and Weibull hazard models, along with two sets of marginal effects for each, are estimated using data on condominium listings in a metropolitan area in Florida.
3D modelling and visualization for Vision-based Vibration Signal Processing and Measurement
Authors: Yao Qi , Shabaz Mohammad , Lohani Tarun Kumar , Wasim Bhatt Mohammed , Panesar Gurpreet Singh , Singh Raj Karan 
Published: April 2021

Abstract
With the technological evolutionary advent, a vision-based approach presents the remote measuring approach for the analysis of vibration. The structure vibration test and model parameter identification in the detection of the structure of the bridge evaluation occupies the important position. The bridge structure to operate safely and reliably is ensured, according to the geological data of qixiashan lead-zinc mine and engineering actual situation, with the aid of international mining software Surpac. To build the 3D visualization model of the application of visualization in mine production are discussed. The results show that the final solid model of -425 stope can accurately display the spatial form of each layer of stope through rotation, amplification and movement. The proposed system is effectually able to perform cutting, volume calculation and roaming in any direction, which has certain guiding significance for mine production management. An accuracy value of 98.75%, the sensitivity of 99%, specificity of 99.64% and PPV of 99.89% are achieved using the proposed 3D modelling and visualization algorithm for vibration signal processing and management.
Screening for asymptomatic diabetes and metabolic comorbidities in pediatric patients during therapy for acute lymphoblastic leukemia
Authors: Larouche Valerie , Bellavance Caroline , Tibout Pauline , Bergeron Sebastien , Simonyan David , Gagné Julie 
Published: April 2021

Abstract

Objectives
Chronic metabolic disturbances related to cancer treatment are well reported among survivors of pediatric acute lymphoblastic leukemia (ALL). However, few studies have investigated the incidence of these complications during the phase of chemotherapy. We evaluated the incidence of acute metabolic complications occurring during therapy in our cohort of patients diagnosed with ALL.

Methods
A prospective study involving 50 ALL pediatric patients diagnosed and treated between 2012 and 2016 in our oncology unit. We collected weight, blood pressure, fasting plasma glucose and hemoglobin A1C (HBA1c) levels during the two years of therapy.

Results
Obesity and overweight occurred in 43 and 25%, respectively among patients and have been reached at 12 months of chemotherapy. About 26% of the patients developed high blood pressure and 14% experienced hyperglycemias without meeting diabetes criteria. There was a significant decrease of HBA1c levels between the beginning and the end of therapy (p<0.0001).

Conclusions
Increase of body mass index in our ALL pediatric patients occurred during the first months of therapy and plateaued after a year of treatment. We should target this population for early obesity prevention. HbA1c levels measured during therapy did not reveal diabetes criteria. Hence, fasting blood glucose levels are sufficient to monitor ALL pediatric patients’ glycemia.
Sensory, voluntary, and motor postural control in children and adolescents with mucopolysaccharidosis
Authors: Yigit Oznur , Aksoy Songul , Akyol Umut , Tokatlı Aysegul , Sivri Hatice Serap 
Published: April 2021

Abstract

Objectives
This study aimed to investigate automatic and voluntary motor control performances, which have an important function in maintaining balance, in children and adolescents with mucopolysaccharidosis (MPS).

Methods
The records of 70 patients were retrospectively analyzed. The results of Computerized Dynamic Posturography (CDP) performed according to the age and development of the individuals were examined. The results of 10 children and adolescents with MPS (mean age: 9.43 ranging from 6 to 14; four males and six females) who completed the sensory analysis, Weight-Bearing Squat Test, and Adaptation Test were retrieved from the database of the CDP. Nine healthy children and adolescents with typical development (mean age: 9.63 ranging from 6 to 14; four males and five females) were included as the control group.

Results
In the sensory analysis test, there was a statistically significant difference between the two groups in the visual ratio parameter. In the adaptation test, there was a statistically significant difference between the two groups in the toes up and toes down trials. There was no statistically significant difference between the groups in the Weight-Bearing Squat test at 0° knee extension and various knee flexions.

Conclusions
Children and adolescents with MPS should be directed to the appropriate exercise and therapy programs to develop postural and balance control, which have a significant effect on their quality of life and the ability to independently perform daily activities of living. In addition to routine hearing assessments for patients with MPS, other objective tests used in the differential diagnosis of balance and vestibular system should also be implemented.
Provocative growth hormone testing in children: how did we get here and where do we go now?
Authors: Kamoun Camilia , Hawkes Colin Patrick , Grimberg Adda 
Published: April 2021

Abstract

Objectives
Provocative growth hormone (GH) tests are widely used for diagnosing pediatric GH deficiency (GHD). A thorough understanding of the evidence behind commonly used interpretations and the limitations of these tests is important for improving clinical practice.

Content
To place current practice into a historical context, the supporting evidence behind the use of provocative GH tests is presented. By reviewing GH measurement techniques and examining the early data supporting the most common tests and later studies that compared provocative agents to establish reference ranges, the low sensitivity and specificity of these tests become readily apparent. Studies that assess the effects of patient factors, such as obesity and sex steroids, on GH testing further bring the appropriateness of commonly used cutoffs for diagnosing GHD into question.

Summary and Outlook
Despite the widely recognized poor performance of provocative GH tests in distinguishing GH sufficiency from deficiency, limited progress has been made in improving them. New diagnostic modalities are needed, but until they become available, clinicians can improve the clinical application of provocative GH tests by taking into account the multiple factors that influence their results.
On preverbalzaiin Mandarin Chinese: its progressive and prepositional functions
Authors: Woo I-hao 
Published: April 2021

AbstractThis study revisits the linguistic properties of preverbalzaiin Mandarin Chinese. Specifically, it examines the syntax of a prepositional phrase headed byzaifunctioning as an adjunct, as the main predicate of a sentence with a continuous reading, as well as a sentence containingzaiwith a progressive reading. It is argued that there is only onezaiand that it always functions as a preposition selecting either a Locative Phrase (LP) or a Zeit Phrase (ZP) as its complement. The study also claims that the different aspectual readings of sentences containingzaiare a result of the different types of complementszaiselects. It is argued that a sentence has a continuous reading whenzaiselects an LP and a progressive one when it selects a ZP as its complement. The proposed analyses not only provide a unified account of the linguistic functions ofzaibut also give a syntactic account of the close relation between the imperfective aspect (in particular, the progressive aspect) and locative elements that has been observed by many previous studies.
Virtual Morris water maze: opportunities and challenges
Authors: Thornberry Conor , Cimadevilla Jose M. , Commins Sean 
Published: April 2021

Abstract
The ability to accurately recall locations and navigate our environment relies on multiple cognitive mechanisms. The behavioural and neural correlates of spatial navigation have been repeatedly examined using different types of mazes and tasks with animals. Accurate performances of many of these tasks have proven to depend on specific circuits and brain structures and some have become the standard test of memory in many disease models. With the introduction of virtual reality (VR) to neuroscience research, VR tasks have become a popular method of examining human spatial memory and navigation. However, the types of VR tasks used to examine navigation across laboratories appears to greatly differ, from open arena mazes and virtual towns to driving simulators. Here, we examined over 200 VR navigation papers, and found that the most popular task used is the virtual analogue of the Morris water maze (VWM). Although we highlight the many advantages of using the VWM task, there are also some major difficulties related to the widespread use of this behavioural method. Despite the task’s popularity, we demonstrate an inconsistency of use – particularly with respect to the environmental setup and procedures. Using different versions of the virtual water maze makes replication of findings and comparison of results across researchers very difficult. We suggest the need for protocol and design standardisation, alongside other difficulties that need to be addressed, if the virtual water maze is to become the ‘gold standard’ for human spatial research similar to its animal counterpart.
Auditory mismatch negativity in bipolar disorder: a focused review
Authors: Raggi Alberto , Lanza Giuseppe , Ferri Raffaele 
Published: April 2021

Abstract
The auditory mismatch negativity, a component of the event-related potential elicited by an unexpected stimulus in a sequence of acoustic stimuli, provides an objective measure of the accuracy of the echoic information processing of the human brain in vivo. Auditory mismatch negativity is also a useful probe of cortical glutamatergic N-methyl-d-aspartate receptor activity and disturbance. Notably, auditory mismatch negativity is consistently impaired in schizophrenia. Because of the wide spectrum extending from bipolar affective illness and schizoaffective psychosis to typical schizophrenia, we examined the literature on auditory mismatch negativity in bipolar disorder with the aim to find any neurophysiological dysfunction concerning pre-attentive information processing shared by these clinical conditions. This focused review includes 26 original articles published in peer-reviewed journals and indexed in the National Institutes of Health National Library of Medicine (PubMed) search system. Overall, evidence is consistent with the finding that auditory mismatch negativity is impaired in bipolar disorder with psychotic features, even though to a lesser extent than in schizophrenia. It must be acknowledged that, in a few twin and family studies, mismatch negativity abnormalities were not specifically associated with bipolar disorder. In conclusion, auditory mismatch negativity research supports the involvement of the N-methyl-d-aspartate system in the pathophysiology of bipolar disorder, as previously assessed for schizophrenia, thus creating an intriguing trait d’union between these two mental illnesses and stimulating the development of novel therapeutic agents. With additional replication and validation, auditory mismatch negativity may be further considered as a correlate of a common psychopathology of schizophrenia and bipolar spectrum illnesses.
Drafted into a Foreign War?
Authors: Sharpe Matthew 
Published: April 2021

AbstractThis paper examines the central criticisms that come, broadly, from the modern, ‘analytic’ tradition, of Pierre Hadot’s idea of ancient philosophy as a way of life.: Firstly, ancient philosophy just did not orcould nothave involved anything like the ‘spiritual practices’ or ‘technologies of the self’, aiming at curing subjects’ unnecessary desires or bettering their lives, contra Hadot and Foucaultet al.Secondly, any such metaphilosophical account of putative ‘philosophy’ must unacceptably downplay the role of ‘serious philosophical reasoning’ or ‘rigorous argument’ in philosophy. Thirdly, claims that ancient philosophy aimed at securing wisdom by a variety of means including but not restricted to rational inquiry are accordingly false also ashistoricalclaims about the ancient philosophers. Fourthly, to the extent that we must (despite (3)) admit that some ancient thinkers did engage in or recommend extra-cognitive forms of transformative practice, these thinkers were not true or ‘mainline’ philosophers. I contend that the historical claims (3) and (4) are highly contestable, risking erroneously projecting a later modern conception of philosophy back onto the past. Of the theoretical or metaphilosophical claims (1) and (2), I argue that the second claim, as framed here, points to real, hard questions that surround the conception(s) of philosophy as a way of life.
The Scandal of Deduction and Aristotle’s Method for Discovering Syllogisms
Authors: Duncombe Matthew 
Published: April 2021

Abstract
(1) If a deductive argument is valid, then the conclusion is not novel. (2) If the conclusion of an argument is not novel, the argument is not useful. So, (3) if a deductive argument is valid, it is not useful. This conclusion, (3), is unacceptable. Since the argument is valid, we must reject at least one premise. So, should we reject (1) or (2)? This puzzle is usually known as the ‘scandal of deduction’. Analytic philosophers have tried to reject (1) but have assumed premise (2). I argue here that Aristotle would deny (2). Aristotle thinks that at least some deductive arguments are useful, even though they present no new conclusions. Thus, Aristotle’s view contrasts with analytic philosophers of logic, who assume that all useful deductive arguments present novel conclusions. I don’t claim that Aristotle ‘solves’ the problem: it was never posed in Aristotle’s time. Rather, I suggest that Aristotle does not face the problem because he assumes deductions can be useful, without presenting novel conclusions. Aristotle’s view of deduction tames the scandal.
Nano titanium oxide for modifying water physical property and acid-resistance of alluvial soil in Yangtze River estuary
Authors: Jili Qu , Yawen Zhang , Weiqing Qu , Xiaoshun Zhou , Lingqing Hu , Jinrui Cheng 
Published: April 2021

Abstract
This study aims to investigate the role of nano TiO2 in modifying the characteristics of Shanghai clayey silt – alluvial soil in Yangtze river estuary. The Shanghai clayey silt is first mixed with nano TiO2 with different size group and content before it is made to undergo liquid and plastic limit tests, standard Proctor compaction tests, and acid-resistant tests. The results show that nano TiO2 can substantially increase the liquid limit and plastic limit of TiO2-treated clayey silt, but can decrease the plasticity index of it to some degree. The result from standard Proctor compaction tests shows that the maximum dry bulk density (MBD) decreases and the optimum water content (OWC) increases compared with untreated samples. Acid-resistance of sample is significantly increased after being treated by nano titanium dioxide. The data provided by this study can be used for not only the soil and water conservation, but also for soil improvement, diversity of vegetables and animals, amelioration of crop land, as well as sustainable development.
Neural activity during cognitive reappraisal in chronic low back pain: a preliminary study
Authors: Ng Sin Ki , Urquhart Donna M. , Fitzgerald Paul B. , Kirkovski Melissa , Cicuttini Flavia M. , Maller Jerome J. , Enticott Peter G. , Rossell Susan L. , Fitzgibbon Bernadette M. 
Published: April 2021

Abstract

Objectives
Chronic pain patients often report higher levels of negative emotions, suggesting reduced ability to regulate emotions effectively, however, little is known of the underlying neural cognitive mechanisms. Therefore, the aim of this study was to explore brain activity and connectivity during cognitive reappraisal in chronic low back pain (CLBP).

Methods
This study recruited 24 female participants; 12 with CLBP and 12 healthy controls. Participants completed an emotion regulation task that involved cognitive reappraisal of negative images during functional magnetic resonance imaging. The negative affect following each image and perceived success of the task were reported. Region of interest and seed-to-voxel analyses were conducted using key regions involved in cognitive reappraisal (i.e., amygdalae and dorsomedial prefrontal cortex) as seed regions.

Results
During the task, there were no group differences in the behavioural measures and blood oxygen level-dependent (BOLD) brain activation in the seed regions. Functional connectivity analysis showed reduced coupling between the amygdalae and dorsolateral prefrontal cortex, orbitofrontal cortex and inferior parietal cortex in the CLBP group compared to controls. Connectivity between the amygdala and inferior parietal cortex positively correlated with the percent of reduced negative affect during reappraisal in the CLBP group.

Conclusions
These preliminary findings demonstrate that individuals with CLBP exhibit similar emotion regulation abilities to healthy controls at the behavioural and BOLD level. However, altered functional connectivity observed in the CLBP group may reduce effective cognitive reappraisal. These results provide evidence for the potential clinical impact of network changes in CLBP.
Long-term postoperative opioid prescription after cholecystectomy or gastric by-pass surgery: a retrospective observational study
Authors: Larsson Viktoria , Nordenson Cecilia , Karling Pontus 
Published: April 2021

Abstract

Objectives
Opioids are commonly prescribed post-surgery. We investigated the proportion of patients who were prescribed any opioids 6–12 months after two common surgeries – laparoscopic cholecystectomy and gastric by-pass (GBP) surgery. A secondary aim was to examine risk factors prior to surgery associated with the prescription of any opioids after surgery.

Methods
We performed a retrospective observational study on data from medical records from patients who underwent cholecystectomy (n=297) or GBP (n=93) in 2018 in the Region of Västerbotten, Sweden. Data on prescriptions for opioids and other drugs were collected from the patients` medical records.

Results
There were 109 patients (28%) who were prescribed opioids after discharge from surgery but only 20 patients (5%) who still received opioid prescriptions 6–12 months after surgery. All 20 of these patients had also been prescribed opioids within three months before surgery, most commonly for back and joint pain. Only 1 out of 56 patients who were prescribed opioids preoperatively due to gallbladder pain still received prescriptions for opioids 6–12 months after surgery. Although opioid use in the early postoperative period was more common among patients who underwent cholecystectomy, the patients who underwent GBP were more prone to be “long-term” users of opioids. In the patients who were prescribed opioids within three months prior to surgery, 8 out of 13 patients who underwent GBP and 12 of the 96 patients who underwent cholecystectomy were still prescribed opioids 6–12 months after surgery (OR 11.2; 95% CI 3.1–39.9, p=0,0002). Affective disorders were common among “long-term” users of opioids and prior benzodiazepine and amitriptyline use were significantly associated with “long-term” opioid use.

Conclusions
The proportion of patients that used opioids 6–12 months after cholecystectomy or GBP was low. Patients with preoperative opioid-use experienced a significantly higher risk of “long-term” opioid use when undergoing GBP compared to cholecystectomy. The indication for being prescribed opioids in the “long-term” were mostly unrelated to surgery. No patient who was naïve to opioids prior surgery was prescribed opioids 6–12 months after surgery. Although opioids are commonly prescribed in the preoperative and in the early postoperative period to patients with gallbladder disease, there is a low risk that these prescriptions will lead to long-term opioid use. The reasons for being prescribed opioids in the long-term are often due to causes not related to surgery.
Multiple structural breaks in cointegrating regressions: a model selection approach
Authors: Schmidt Alexander , Schweikert Karsten 
Published: April 2021

Abstract
In this paper, we propose a new approach to model structural change in cointegrating regressions using penalized regression techniques. First, we consider a setting with known breakpoint candidates and show that a modified adaptive lasso estimator can consistently estimate structural breaks in the intercept and slope coefficient of a cointegrating regression. Second, we extend our approach to a diverging number of breakpoint candidates and provide simulation evidence that timing and magnitude of structural breaks are consistently estimated. Third, we use the adaptive lasso estimation to design new tests for cointegration in the presence of multiple structural breaks, derive the asymptotic distribution of our test statistics and show that the proposed tests have power against the null of no cointegration. Finally, we use our new methodology to study the effects of structural breaks on the long-run PPP relationship.
Generating functions for a lattice path model introduced by Deutsch
Authors: Prodinger Helmut 
Published: April 2021

AbstractThe lattice path model suggested by E. Deutsch is derived from ordinary Dyck paths, but with additional down-steps of size −3, −5, −7, . . . . For such paths, we find the generating functions of them, according to length, ending at leveli, both, when considering them from left to right and from right to left. The generating functions are intrinsically cubic, and thus (fori= 0) in bijection to various objects, like even trees, ternary trees, etc.