bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationship of Sex and Diagnosis With Symptoms and Illness Impact in Urologic Chronic Pelvic Pain; A Mapp Network Analysis
Authors: Naliboff Bruce D. , McWilliams Tara , Clemens J. Quentin , Pontari Michael A. , Stephens‐Shields Alisa J. , Moldwin Robert , Sutcliffe Siobhan , Mullins Chris , Landis J. Richard 
Published: December 2024

ABSTRACTObjectiveTo assess differences in clinical presentation and illness impact in men and women presenting with urologic chronic pelvic pain syndrome (UCPPS) and between men diagnosed with interstitial cystitis/bladder pain syndrome (IC/BPS) or chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).Methods356 men and 605 women from six sites across the United States were assessed using a comprehensive set of demographic, symptom, and illness impact measures. Multivariable regression analyses examined differences between men and women and between men previously diagnosed with CP/CPPS or IC/BPS. In a stepwise manner, analyses tested group differences, controlling for demographic variables including symptom duration and presence of bladder pain that varied with filling and voiding.ResultsMen diagnosed with IC/BPS had the most severe UCPPS symptoms, followed by women with IC/BPS, and then men with CP/CPPS only. While men and women showed similar patterns of symptoms across most of the variables, women had increased widespread non‐pelvic pain, greater pelvic floor tenderness on exam, and higher self‐reported sensory sensitivity compared to men. About 60% of men diagnosed with CP/CPPS only reported bladder symptoms of painful filling or relief with voiding.ConclusionsA generally shared symptom pattern was found across men and women irrespective of diagnostic labels suggesting the use of key marker symptoms, such as severity of bladder symptoms and widespread pain, to better identify subgroups of UCPPS rather than diagnostic category. Women may have an increased likelihood of increased sensitivity and central sensitization than men, including those men with IC/BPS.Trial RegistrationClinicalTrials.gov Identifier: NCT02514265 ‐ MAPP Research Network: Trans‐MAPP Study of Urologic Chronic Pelvic Pain: Symptom Patterns Study (SPS).
Noninvasive Grading of Liver Fibrosis Based on Texture Analysis From MRI‐Derived Radiomics
Authors: Gotta Jennifer , Gruenewald Leon D. , Reschke Philipp , Booz Christian , Mahmoudi Scherwin , Stieltjes Bram , Choi Moon Hyung , D'Angelo Tommaso , Bernatz Simon , Vogl Thomas J. , Sinkus Ralph , Grimm Robert , Strecker Ralph , Haberkorn Sebastian , Koch Vitali 
Published: December 2024

ABSTRACTGiven the increasing global prevalence of metabolic syndrome, this study aimed to assess the potential of MRI‐derived radiomics in noninvasively grading fibrosis. The study included 79 prospectively enrolled participants who had undergone MRE due to known or suspected liver disease between November 2022 and September 2023. Among them, 48 patients were diagnosed with histopathologically confirmed liver fibrosis. A total of 107 radiomic features per patient were extracted from MRI imaging. The dataset was then divided into training and test sets for model development and validation. Stepwise feature reduction was employed to identify the most relevant features and subsequently used to train a gradient‐boosted tree model. The gradient‐boosted tree model, trained on the training cohort with identified radiomic features to differentiate fibrosis grades, exhibited good performances, achieving AUC values from 0.997 to 0.998. In the independent test cohort of 24 patients, the radiomics model demonstrated AUC values ranging from 0.617 to 0.830, with the highest AUC of 0.830 (95% CI 0.520–0.830) for classifying fibrosis grade 2. Incorporating ADC values did not improve the model's performance. In conclusion, our study emphasizes the significant promise of using radiomics analysis on MRI images for noninvasively staging liver fibrosis. This method provides valuable insights into tissue characteristics and patterns, enabling a retrospective liver fibrosis severity assessment from nondedicated MRI scans.
The Many Indicators of Nonprofit Success as Seen by Nonprofit Leaders
Authors: Maier Florentine , Zheng Wenjuan , Brandtner Christof , Cornips Leila 
Published: December 2024

ABSTRACTNonprofit organizations are increasingly compelled to demonstrate their success to stakeholders, drawing scholarly interest toward systematizing indicators of their success. But what best indicates success is in the eye of the beholder, as success is socially constructed. This paper examines the multifaceted success indicators used by nonprofit leaders in practice and explores how they align with scholarly conceptions of nonprofit success. We develop a framework of nonprofit success from the perspective of nonprofit leaders that is more comprehensive and generalizable than previous ones by analyzing responses from leaders of 861 randomly sampled nonprofit organizations in three metropolitan regions representing different institutional contexts—Vienna (Austria), Shenzhen (China), and San Francisco (USA). Despite contextual differences, leaders' understandings have much in common across settings. The indicators overlap with existing scholarly understandings of nonprofit performance and effectiveness, focusing on internal actions and external stakeholder relationships. However, our findings also uncover two practically relevant groups of indicators that are under‐appreciated in scholarly discourse: relationships within the organization (cohesiveness and social inclusion), and the uptake behavior of external stakeholders (engagement with the organization's offerings). Our findings categorize these indicators in terms of whether they manifest inside or outside the organization and whether they emphasize actions or relationships. The two‐dimensional framework thereby maps common ground among nonprofit leaders across diverse national and organizational contexts, noting how the priority of success aspects varies. Our comparative data underscore the wide‐ranging applicability of the proposed framework, illuminating new directions for research on nonprofit success.
Characterisation of GPR17‐expressing oligodendrocyte precursors in human ischaemic lesions and correlation with reactive glial responses
Authors: Raffaele Stefano , Clausen Bettina Hjelm , Mannella Francesca Carolina , Wirenfeldt Martin , Marangon Davide , Tidgen Sarah Boe , Corradini Silvia , Madsen Kirsten , Lecca Davide , Abbracchio Maria Pia , Lambertsen Kate Lykke , Fumagalli Marta 
Published: December 2024

AbstractWhite matter damage and subsequent demyelination significantly contribute to long‐term functional impairment after ischaemic stroke. Identifying novel pharmacological targets to restore myelin integrity by promoting the maturation of oligodendrocyte precursor cells (OPCs) into new myelinating oligodendrocytes may open new perspectives for ischaemic stroke treatment. In this respect, previous studies highlighted the role of the G protein‐coupled membrane receptor 17 (GPR17) as a key regulator of OPC differentiation in experimental models of brain injury, including ischaemic stroke. To determine the translational value of GPR17 as a possible target in the context of human disease, we exploited immunohistochemistry to characterise the distribution of GPR17‐expressing cells in brain tissue samples from ischaemic stroke cases and correlated it with the reactive state of neighbouring glial cells. The results showed that GPR17 specifically decorates a subpopulation of differentiation‐committed OPCs, labelled by the peculiar marker breast carcinoma‐amplified sequence 1 (BCAS1), that accumulates in the peri‐infarct region in the later stages after the ischaemic event. Interestingly, the response of GPR17‐expressing cells appears to be paralleled by the switch of reactive microglia/macrophages from a phagocytic to a dystrophic phenotype and by astrocytic scar formation. A negative correlation was found between GPR17‐expressing OPCs and reactive microglia/macrophages and astrocytes surrounding chronic ischaemic lesions in female subjects, while the same relationship was less pronounced in males. These results were reinforced by bioinformatic analysis of a publicly available transcriptomic dataset, which implicated a possible role of inflammation and defective neuron‐to‐OPC communication in remyelination failure after ischaemic damage. Hence, these data strengthen the relevance of GPR17‐based remyelinating therapies for the treatment of ischaemic stroke. © 2024 The Author(s). The Journal of Pathology published by John Wiley & Sons Ltd on behalf of The Pathological Society of Great Britain and Ireland.
Magnetic field‐enhanced anisotropic electrorheological elastomer with magnetic/electric dual‐responsive rod particles
Authors: Zhao Xinye , Niu Chenguang , Jia Zhaomin , Dong Xufeng , Xiong Xiaoyan 
Published: December 2024

AbstractAs a type of field‐responsive smart material, electrorheological elastomers (EREs) have an adjustable modulus that is significantly affected by the orientation of the pre‐structures formed by dispersed particles. However, the imperfect orientation of the particles in the matrix under an external electric field limits the electrorheological (ER) performance of EREs. To solve this problem, rod‐shaped Fe3O4@TiO2 magnetic/electric dual‐responsive particles were fabricated and used to prepare novel EREs that were cured under a magnetic field, and EREs cured under an electric field served as a control group. Compared with the control group, more robust and denser particle chain structures were observed in the EREs cured under a magnetic field, and the initial modulus and relative electrorheological effect (ER) were superior to those of the control group. This method can be used to prepare high‐performance EREs with strong zero‐field mechanical properties and a wide modulus adjustment range suitable for engineering applications.Highlights
The magnetic/electric dual‐responsive rod‐shaped Fe3O4@TiO2 particles were prepared.
EREs filled with Fe3O4@TiO2 particles were prepared under magnetic or electric field.
More robust and denser particle chains were formed in the EREs cured under a magnetic field.
The EREs solidified under a magnetic field have higher relative ER effects.
Systematic mapping of experimental approaches to studying common mycorrhizal networks in arbuscular mycorrhiza
Authors: Lehmann Anika , Rillig Matthias C. 
Published: December 2024

Societal Impact StatementCommon mycorrhizal networks (CMN) capture the imagination of researchers and the public alike and have played a large role in communicating about mycorrhiza in general. With many of the claims about the functional importance of CMN recently under intense scrutiny, it becomes important to assess the literature on this topic. We systematically map experimental approaches, uncovering large data gaps, with evidence from field studies and data on ecosystem processes lacking. Very few studies meet the strictest recommended criteria, limiting our understanding of CMN‐mediated effects on plants and soils. A renewed research effort needs to unravel the contribution of CMNs under global environmental change.Summary
Common mycorrhizal networks (CMN) are a research area within mycorrhizal ecology, studying the effects of mycorrhizal fungi linking plant roots. Experimentally studying the functioning of such networks is challenging because of the presence of many different types of network links that give rise to potentially confounding effects.
Here, we collect, collate, and describe the research evidence for common mycorrhizal networks, specifically for arbuscular mycorrhiza (AM), using a systematic mapping approach.
We find that not all studies tested networks formed exclusively by AM fungi, but that other filamentous fungi were present and that very few articles report on experiments fulfilling the current stringent definition (demanding hyphal continuity between plant roots). Furthermore, most research is limited to controlled environmental conditions with certain plant, fungal, and resource‐transfer variables measured, while microbial community responses or ecosystem processes are neglected.
Given the broad interest in this topic, we see a need to strengthen the evidence base on “common mycorrhizal networks” in AM fungi, necessitating a renewed research effort focusing on a range of levels of mechanistic resolution (from simple to complex networks with and without hyphal continuity). Additionally, neglected experimental situations (e.g., field studies in general) and microbial community or ecosystem‐level responses should be included in future research.
Papilledema in Children With Cystic Fibrosis Receiving Elexacaftor/Tezacaftor/Ivacaftor: A Multicenter Case Series
Authors: Kam Charissa W. , McKinzie Cameron J. , Omecene Nicole E. , Peters Stacy , Pettit Rebecca S. , Poisson Margaret O. , Witte Jennifer 
Published: December 2024

ABSTRACTFollowing the approval of elexacaftor/tezacaftor/ivacaftor (ETI), there have been post‐marketing reports and published cases of papilledema and intracranial hypertension in children with cystic fibrosis (CF) taking ETI. In those reports, the patients often presented with marked symptoms and concomitant hypervitaminosis A. In this multicenter case series, we report eight cases of papilledema in children with CF taking ETI that were diagnosed via routine eye exam, the majority of whom presented with minimal to no symptoms and all had normal serum Vitamin A levels.
Gynocentric concerns in the choreopoems of Ntozake Shange
Authors: Kanagavalli C. 
Published: December 2024

AbstractChoreopoetry is a unique form of artistic expression that combines poetry, music, and dance to create a multi‐dimensional performance art form. Shange's choreopoems challenged societal norms around gender, sexuality, and race, and helped to pave the way for feminist and African‐American literature. This research paper analyzes the gynocentric concerns in Ntozake Shange's choreopoems, which are a combination of poetry, music, and dance. Through the lens of gynocentrism, the paper explores how Shange's works prioritize the experiences and perspectives of Black women and challenge societal norms around gender and sexuality. The findings of the study, are organized thematically and supported with quotes and examples from the choreopoems. The paper discusses the themes and content of Shange's two most famous choreopoems, “ For Colored Girls Who Have Considered Suicide/When the Rainbow Is Enuf”, “Spell No. 7,” and “Boogie Woogie Landscape” and compares the gynocentric concerns in each. Additionally, the paper examines the reception of Shange's choreopoems by audiences and critics and the impact of her work on feminist and African‐American literature. Overall, this research contributes to the understanding of Shange's choreopoems as feminist literature and highlights the importance of using gynocentrism as a framework for analyzing works that prioritize women's experiences and perspectives.
Hole‐Transport‐Layer‐Free Organic Solar Cells with Enhanced Efficiency Upon Halogenated Solvent Treatment
Authors: Wu Weiwei , Huang Pengru , Gao Yuan , Wan Ji , Sun Rui , Min Jie 
Published: December 2024

AbstractTypical PEDOT:PSS hole‐transporting layers frequently present some issues, including mismatched energy levels, high acidity, severe hygroscopicity, etc., all of which significantly weaken device performance. Herein, an approach of halogenated solvent treatment to modulate the physical properties of indium tin oxide (ITO) substrates is employed. Four halogenated‐ITO anodes (named ITO‐F, ITO‐Cl, ITO‐Br and ITO‐I) are achieved by ITO substrates immersed in hydrogen peroxide co‐solvents mixed with 1,2‐difluorobenzene, 1,2‐dichlorobenzene, 1,2‐dibromobenzene and 1,2‐diiodobenzene, respectively, and upon UV illumination. The work functions of the ITO‐F/Cl/Br/I anodes increase from 4.63 eV for ITO to 5.30, 5.32, 5.24, and 5.28 eV, respectively, which are close to 5.22 eV for ITO/PEDOT:PSS. Additionally, the investigated PM6:L8‐BO:BTP‐eC9 devices based on various anodes showed power conversion efficiencies (PCEs) of 17.81% for ITO‐F, 19.48% for ITO‐Cl, 17.05% for ITO‐Br, 17.34% for ITO‐I and 18.70% for ITO/PEDOT:PSS, respectively. In particular, a comprehensive experimental analysis is conducted to establish connections between theoretical calculations, blend morphology and physical dynamics, and further elucidate the factors that cause differences in device efficiencies. This work manifests the advantages of the proposed halogenated ITO for realizing highly efficient organic photovoltaics.
Enhancing the Chemical Reactivity of Graphene through Substrate Engineering
Authors: Tu Jia , Yan Mingdi 
Published: December 2024

AbstractCovalent functionalization of pristine graphene can modify its properties, enabling applications in optoelectronics, biomedical fields, environmental science, and energy. However, the chemical reactivity of pristine graphene is relatively low, and as such, methods have been developed to increase the reactivity of graphene. This review focuses on substrate engineering as an effective strategy to enhance the reactivity of graphene through strain and charge doping. Nanoparticles, metals with different crystal orientations, and stretchable polymers are employed to introduce strains in graphene, leading to enhanced chemical reactivity and increased degree of functionalization. Charge doping through orbital hybridization with metals and charge puddles induced by oxide substrates generally enhance the reactivity of graphene, while alkyl‐modified surfaces and 2D materials often reduce graphene reactivity via charge screening and van der Waals interactions that increase the stability of the graphene layer, respectively. This review summarizes methods for creating and characterizing strains and charge doping in graphene and discusses their effects on the chemical functionalization of graphene in various reactions.
Carbon Nanostructures Derived from In Situ Grown ZIF Nanocages within Bacterial Cellulose for AC‐Filtering Electrochemical Capacitors
Authors: Baranwal Rishav , Lin Xueyan , Qiao Yinxuan , Tan Haiyan , Goryll Michael , Fan Zhaoyang 
Published: December 2024

AbstractElectrochemical capacitors (ECs) offer superior specific capacitance for energy storage compared to traditional electrolytic capacitors but face limitations in alternating current (AC) filtering due to the need for balancing fast response and high capacitance. This study addresses these challenges by developing a freestanding nanostructured carbon electrode, derived from the rapid carbonization of bacterial cellulose (BC) embedded with zeolitic imidazolate framework 8 (ZIF‐8) and in situ formed carbon nanotubes (CNTs). The electrode exhibits an exceptionally low area resistance of 9.8 mΩ cm2 and a high specific capacitance of 2.1 mF cm−2 at 120 Hz, maintaining performance even at high frequencies. Stacking these electrodes enhances the capacitance to 5.3 mF cm−2, with the phase angle degrading to −74.4° at 120 Hz; however, they retain a phase angle below −45° up to ≈50 kHz, demonstrating excellent high‐frequency performance. Furthermore, connecting three aqueous units in series as an integrated cell or utilizing organic electrolytes extends the voltage window to 2.4 V, enhancing their suitability for high‐voltage applications. Ripple voltage analysis under various loads and frequencies indicates effective filtering capabilities, highlighting the potential of these nanostructured ECs for next‐generation electronic applications.
Boosting Photovoltaic Efficiency: The Role of Functional Group Distribution in Perovskite Film Passivation
Authors: He Qingquan , Pan Shicheng , Zhang Tao , Chen Xiuyuan , Chen An , Xu Gang , Zhou Kun , Li Jing , Zhu Hongwei , Bakr Osman M. , Pan Jun 
Published: December 2024

AbstractThe utilization of small organic molecules with appropriate functional groups and geometric configurations for surface passivation is essential for achieving efficient and stable perovskite solar cells (PSCs). In this study, two isomers, 4‐sulfonamidobenzoic acid (4‐SA) and 3‐sulfamobenzoic acid (3‐SA), both featuring sulfanilamide and carboxyl functional groups arranged in different positions, are evaluated for their effectiveness in passivating defects of the perovskite layer. The calculation and characterization results reveal that 3‐SA, with its meta‐substitution, offered superior passivation compared to the para‐substituted 4‐SA, leading to enhanced charge carrier dynamics and extraction efficiency. The devices treated with 3‐SA demonstrates a notable increase in power conversion efficiency from 21.50% to 23.30%. Moreover, these devices maintain over 90% of their initial efficiency after 2000 h in a 30% relative humidity environment, showcasing exceptional long‐term stability. This research advances strategic design approaches for small molecule passivation, providing critical insights for the enhancement of perovskite optoelectronic applications.
Direct Tensile Testing of Free‐Standing Ultrathin Polymer Films on Liquid Surface at High Temperature
Authors: Lee Tae‐Ik , Kim Ji Hun , Oh Eun Sung , Kim Taek‐Soo 
Published: December 2024

AbstractThe fragile nature of ultrathin polymer films poses a challenge for precise mechanical property measurements in a free‐standing state, despite their critical importance for the fabrication and performance of advanced electronic devices under thermal loading. Here, a novel high‐temperature tensile testing method for free‐standing ultrathin polymer films using a film on heated liquid (FOHL) platform is proposed. Glycerol is chosen for the thermally stable liquid platform for its high surface tension, high boiling point, miscibility with water, and chemical stability. A defect healing process of the specimen on the heated liquid effectively eliminates preexisting defects of the brittle polymer sample, enabling precise tensile property measurements at elevated temperatures. The methodology is validated through experiments on polystyrene (PS) films of varying thicknesses (50–400 nm) at elevated temperatures of 25–100 °C, demonstrating the influence of temperature and thickness on tensile properties. Decreasing elastic modulus with increasing temperature and decreasing thickness of ultrathin PS films is accurately measured. The proposed method provides a reliable method todirectly evaluate the tensile properties of ultrathin films in high‐temperature conditions.
A case of dystocia due to conjoined twin monster in a crossbred jersey dairy cow
Authors: Srilatha Bethapudi , Phaneendra Mudiki S. S. V. , Rao Kondareddy Prabhakar , Rani Undeti Teja , Haritha Gurram S. 
Published: December 2024

AbstractA pluriparous crossbred jersey cattle in its third parity was brought to the hospital with a history of prolonged straining having advanced pregnancy and present in last trimester. Physical and per vaginal was done and tentatively confirmed as fetal cause of dystocia. Manual traction was performed but was futile and caesarean section was performed by a left lower abdominal incision under local anaesthesia using 2% lignocaine. A dead conjoined twin monster with diprosopus, dibrachius, dicaudatus and tetrapus fetus was delivered. The dam was recovered successfully with good prognosis.