bluuebunny/crossref_metadata_2025_split huggingface dataset:
Appraisal of Anti-Arthritic and Anti-Inflammatory Potential of Folkloric
Medicinal Plant Peganum harmala
Authors: Akhtar Muhammad Furqan , Raza Syed Ahmad , Saleem Ammara , Hamid Irfan , Ashraf Baig Mirza Muhammad Faran , Sharif Ali , Sohail Kashif , Javaid Zeeshan , Saleem Uzma , Rasul Azhar 
Published: February 2021

Background:
Peganum harmala is traditionally used to manage rheumatoid arthritis (RA) and other inflammatory conditions. However, its use against RA has not been scientifically evaluated. The current study was designed to assess the anti-arthritic and anti-inflammatory activities of the methanolic extract of P. harmala leaves by in vitro and in vivo methods.

Methods:
The in vitro assays were carried out to determine the effect of plant extract on inhibition of egg albumin denaturation and human red blood cell membrane (HRBC) stabilization. Moreover, 2,2-diphenyl-1-picrylhydrazyl (DPPH) scavenging activity was performed to determine the antioxidant potential. In vivo anti-arthritic activity was performed by determining the curative effect against Complete Freund’s adjuvant (0.1 ml). The plant extract was administered to rats orally at 200, 400 and 600 mg/kg/day for 21 days.

Results:
The values of IC50 of plant extract in protein denaturation, stabilization of HRBC and DPPH assays were 77.54 mg/ml, 23.90 mg/ml and 58.09 µg/ml respectively. Moreover, the plant extract significantly attenuated the poly-arthritis and weight loss, anemia and paw edema. The plant extract restored the level of C-reactive protein, rheumatoid factor, alanine transaminase, aspartate transaminase and alkaline phosphatase in poly-arthritic rats. Moreover, the plant extract restored the immune organs weight in treated rats. Treatment with P. harmala also significantly subdued the oxidative stress by reinstating superoxide dismutase, reduced glutathione, catalase and malondialdehyde in poly-arthritic rats. The plant extract notably restored the prostaglandin-E2 and tumor necrosis factor (TNF)-α in the serum of poly-arthritic rats.

Conclusion:
It was concluded that P. harmala extract had potential antioxidant, anti-inflammatory and antiarthritic activities which primarily might be attributed to alkaloids, flavonoids and phenols.
Dietary Intakes and Food Habits of Wheelchair Basketball Athletes Compared
to Gym Attendees and Individuals who do not Practice Sport Activity
Authors: Toti Elisabetta , Cavedon Valentina , Raguzzini Anna , Fedullo Anna Lucia , Milanese Chiara , Bernardi Elisabetta , Bellito Sheila , Bernardi Marco , Sciarra Tommaso , Peluso Ilaria 
Published: February 2021

Background:
Mediterranean diet (Med-D) has been previously suggested for athletes, but Paralympics usually have a low intake of plant foods. Orthorexia nervosa (ON) can drive dietary intake of both athletes and gym attendees.

Objective:
We aimed to compare dietary intakes and food habits of elite wheelchair basketball athletes (WBA) and able-bodied individuals who practice or not sport activity and with different fat mass percentage (FM%).

Methods:
We recruited 15 WBA from the Italian National team and 3 control groups (15 each group): healthy individuals who do not practice any sport activity (NSA) and gym attendees with low (GAL, FM%<17) and high (GAH, FM%>18) FM%. Food consumption was monitored by 3-d diary, while Med-D scores and ON score were evaluated through standardized questionnaires. In WBA we also assessed Neurogenic Bowel Dysfunction (NBD), GastroEsophageal Reflux Disease (GERD), allergy questionnaire for athletes (AQUA) and Starvation Symptoms Inventory (SSI).

Results:
In WBA, ON correlated with GERD and SSI. WBA and GAH with eating behavior of ON had higher adherence to Med-D, whereas NSA had less adherence to Med-D. Sub-score including fruits, vegetables and legumes, was higher in the GAL and GAH groups compared to the WBA and NSA groups. Med-D was inversely related to animal protein intake (PRO-AN) in NSA and GAL. FM% was inversely related to PRO-AN in WBA and GAH, and to ON only in GAH. In WBA PRO-AN and vegetable protein intake correlated with both carbohydrate and energy intakes.

Conclusions:
In WBA, commitment to wellness (ON and Med-D adherence) could be a response to gastrointestinal and starvation symptoms. WBA should be involved in setting their own individualized dietary strategies.
A Review of Clustering Algorithms: Comparison of DBSCAN and K-mean
with Oversampling and t-SNE
Authors: Bajal Eshan , Katara Vipin , Bhatia Madhulika , Hooda Madhurima 
Published: February 2021

Abstract:
The two most widely used and easily implementable algorithm for clustering and classification-based analysis of data in the unsupervised learning domain are Density-Based Spatial Clustering of Applications with Noise and K-mean cluster analysis. These two techniques can handle most cases effective when the data has a lot of randomness with no clear set to use as a parameter as in case of linear or logistic regression algorithms. However few papers exist that pit these two against each other in a controlled environment to observe which one reigns supreme and conditions required for the same. In this paper, a renal adenocarcinoma dataset is analyzed and thereafter both DBSCAN and K-mean are applied on the dataset with subsequent examination of the results. The efficacy of both the techniques in this study is compared and based on them the merits and demerits observed are enumerated. Further, the interaction of t-SNE with the generated clusters are explored.
Cost-per-remitter with esketamine nasal spray versus standard of care for treatment-resistant depression
Authors: Desai Urvi , Kirson Noam Y , Guglielmo Andrea , Le Hoa H , Spittle Timothy , Tseng-Tham Joshua , Shawi May , Sheehan John J 
Published: February 2021

Aim:
Estimate the cost-per-remitter with esketamine nasal spray plus an oral antidepressant (ESK + oral AD) versus oral AD plus nasal placebo (oral AD + PBO) among patients with treatment-resistant depression.
Patients & methods:
An Excel-based model was developed to estimate the cost-per-remitter for ESK + oral AD versus oral AD + PBO over 52 weeks from multiple US payer perspectives. Clinical end points and cost inputs were derived from clinical trials and the literature, respectively.
Results:
Under the base-case scenario, the cost-per-remitter for ESK + oral AD and oral AD + PBO were as follows: Commercial: US$85,808 versus US$100,198; Medicaid: US$76,236 versus US$96,067; Veteran’s Affairs: US$77,765 versus US$104,519; and Integrated Delivery Network: US$103,924 versus US$142,766.
Conclusion:
The findings suggest that ESK + oral AD is a cost-efficient alternative treatment for treatment-resistant depression compared with oral AD + PBO.
Social Physique Anxiety in Female Adolescents at Bandung Middle School
Authors: Hadiani Nidya Fildza , Hidayati Nur Oktavia , Sari Citra Windani Mambang 
Published: February 2021

Background: Adolescence is a transition from childhood to adulthood, along with physical and emotional changes. One significant difference is physical appearance. Adolescents tend to be afraid of negative evaluations from others for their physical appearance or social physique anxiety. Objective: This study aimed to determine the social physique anxiety in female adolescents at Bandung Middle School. Methods: This study's method was a descriptive quantitative method using a total population technique with a sample of 331 female high school students in Bandung Middle School. The measurement instrument that was used in this study was SPAS-C (Social Physique Anxiety for Children). Analysis of the data was conducted using the average score of social physique anxiety and was presented as a percentage. Result: This study showed that most respondents had a lower score than social physique anxiety average score with a several 176 respondents (53.2%), in comparison 155 respondents (46.8%) had a higher score than social physique anxiety average score. Based on the study results, comparing the number of respondents who had a lower score than the social physique anxiety average score with the number of respondents who had a higher score than the social physique anxiety average score did not significantly differ. Conclusions: Preventive solutions for social physique prevention are essential. Schools can make a consultation schedule or use an online consultation system and work with community health centers to provide health education and knowledge about social physique anxiety and the influencing factors and its prevention.
VARIAÇÃO TERMINOLÓGICA NO DOMÍNIO DO DIREITO DO TRABALHO
Authors: Beltramini Carina , Babini Maurizio 
Published: February 2021

As sentenças judiciais trabalhistas têm grande relevância dentro e fora da seara jurídica, já que é por meio desse tipo de gênero textual que o magistrado decide os conflitos de interesses submetidos à sua autoridade. O objetivo geral deste trabalho é analisar a variação terminológica em um conjunto de sentenças judiciais trabalhistas. Nossa pesquisa está baseada nas teorias de Barros, (2004; 2007), Cabré (1999), Krieger; Finatto (2004), Faulstich (2001). Para efetuarmos esse trabalho constituímos um corpus composto de sentenças judiciais trabalhistas publicadas nos anos de 2014 a 2018. Sucessivamente, procedemos à coleta dos termos por meio do programa Hyperbase e esses termos foram organizados em um sistema nocional. Em seguida, analisamos o conjunto de termos encontrados, destacando os diferentes tipos de variantes encontradas.
Palavras-chave: Sentença judicial trabalhista. Terminologia. Variação terminológica.
The effectiveness of locally injected platelet-rich plasma on orthodontic tooth movement acceleration:
Authors: Li Ziyu , Zhou Jialiang , Chen Song 
Published: February 2021

ABSTRACT

Objectives
To critically appraise the current evidence available from animal studies pertaining to the effectiveness of platelet-rich plasma (PRP) in accelerating orthodontic tooth movement.

Materials and Methods
Electronic searches of nine databases were conducted up to June 2020, followed by a hand search of the reference list of eligible studies. The study design required was prospective controlled animal studies. The primary outcome assessed was the rate of orthodontic tooth movement. The secondary outcome evaluated was histological changes after PRP application. Following study retrieval and selection, relevant data were extracted. Risk-of-bias (RoB) assessment was done using the Systematic Review Center for Laboratory Animal Experimentation's Risk of Bias Tool (SYRCLE's Risk of Bias Tool). Two review authors conducted the work of searching, study selection, and quality assessment independently and in duplicate.

Results
Of 193 studies, 5 animal studies were included in this systematic review. Three studies found a positive correlation between PRP injection and tooth movement acceleration, along with corresponding histological changes. Two studies detected no significant difference in tooth movement rate after PRP application.

Conclusions
Based on the current limited evidence, the efficacy of PRP on tooth movement acceleration remains debatable. More well-designed randomized controlled trials involving humans are called for to obtain more clinically significant conclusions.
Forbilder og danning i profesjonsutdanningene: Casestudie – Krigsskolen
Authors: Magnussen Leif Inge , Torgersen Glenn Egil , Boe Ole 
Published: February 2021

This research paper investigates the meaning of role models in higher education. As a case, the Norwegian Military Academy (NMA), which educates military officers for the Norwegian army, is used. Particularly investigated is how role models can be seen as resources in the “learning landscape” surrounding the army officer cadets through their 3 years of learning and Bildung processes. Data used in this work stem from an ethnographic fieldwork following a class of cadets at the NMA through their practical training, off-campus. Officer cadets in interviews report both intentional and unintentional use of role models as a resource in their learning landscapes. By critical educational interpretation of this ongoing practice, using the frame of Wolfgang Klafkis Bildungstheory and “the perfect action principle”, the relationships between this practice and the NMA’s own Bildungideals are questioned. Role models are at the NMA linked to their own leaders, culture and practice. This narrows what is valid practice and can enforce a self-driven power structure and a one-dimensional understanding of how leadership should be performed, where only people within this culture can be seen as participants. We argue that the risks of this NMA practice are related to organisational narcissism and a possible distorted reality orientation, where the NMA fails it’s given educational tasks related to the need of the society and future demands of war.
ROBOTICS IN THE PENITENTIARY EDUCATION SYSTEM AS ONE OF THE WAYS OF PRISONERS’ RESOCIALIZATION
Authors: Курушин Павел Дмитриевич 
Published: February 2021

Рассматривается проблема перевоспитания заключенных, проходивших обязательное обучение в школе при колонии, средствами, которые предоставляет школьное дополнительное образование. Анализируются важные для ресоциализации психологические аспекты личности заключенных, на основе которых делается предположение о полезности изучения робототехники в школе при исправительных колониях. Затрагиваются ключевые характеристики как самого предмета «робототехника», так и отношение заключенных к изучению данной области.
На примере учеников класса показывается эффективность влияния робототехники на эмоциональное состояние заключенных обучающихся, что мотивирует их к изучению остальных предметов основной образовательной программы школы. Эксперимент проведен на базе муниципального общеобразовательного учреждения при колонии в городе Томске, который наглядно показывает существенное улучшение качества усваиваемых знаний заключенными. Представлены результаты эксперимента.
The proposed article examines the problem of rehabilitation of convicts who completed compulsory education at the colony school (hereinafter referred to as a penitentiary-type school), which is urgent for modern society, by means of additional school education. The psychological aspects of the personality of prisoners, important for resocialization, are analyzed, on the basis of which an assumption is made about the usefulness of studying robotics at school in correctional colonies. The key characteristics of both the subject of robotics itself and the attitude of prisoners to the study of this field are touched upon.
Using the example of students from one of the school classes, the effectiveness of the influence of robotics on the emotional state of prisoners is shown, which motivates them to study the rest of the subjects of the main educational program of the school. The experiment was carried out on the basis of a municipal educational institution at a colony in the city of Tomsk, which clearly shows a significant improvement in the quality of assimilated knowledge by prisoners. The results of the experiment are presented.
HUBUNGAN PERTAMBAHAN BERAT BADAN IBU SELAMA HAMIL DENGAN BERAT BADAN BAYI BARU LAHIR DI KLINIK DANDY MABAR KECAMATAN MEDAN DELI TAHUN 2012-2013
Authors: Pardosi Maida 
Published: February 2021

Pertambahan berat badan ibu selama hamil sangat penting diperhatikan, sebab jika pertambahan berat badan tidak mencukupi dapat menghambat pertumbuhan bayi. Hasil survei awal di Klinik Dandy terdapat 124 ibu bersalin pada priode 2012-2013, sebanyak 16 ibu melahirkan bayi dengan berat lahir <2500 gram, 97 ibu dengan berat bayi lahir >2500-4000 gram dan 11 ibu bersalin dengan beratlahir >4000 gram. Penelitian bertujuan untuk mengetahui hubungan pertambahan berat badan ibu selama hamil dengan berat badan bayi baru lahir. Penelitian bersifat analitik dengan desain cross sectional retrospektif. Populasi penelitian adalah semua ibu yang memeriksakan diri dan melahirkan di Klinik Dandy tahun 2012-2013 berjumlah 124 orang dan jumlah sampel 124 orang (total sampling). Jenis data yang digunakan adalah data sekunder. Pengolahan data dengan cara statistik analisa univariat dan bivariat (uji chi-square). Hasil penelitian menunjukan ada hubungan pertambahan berat badan ibu selama hamil dengan berat badan bayi baru lahir dan nilai p=0,005 (<0,05). Disarankan kepada petugas kesehatan Klinik Dandy agar memberikan konsling kepada ibu hamil yang memeriksakan diri dan memantau pertambahan berat badan ibu selama hamil. Kata Kunci: berat badan, ibu hamil, bayi baru lahir
Test Antifungal Phatogen Extract Secondary Metabolites Of Endophytic Fungi Raru Plant (Cotylelobium melanoxylon)
Authors: Hasanah Uswatun , Riwayati Riwayati , Idramsa Idramsa 
Published: February 2021

This study aims to determine the ability of extracts secondary metabolites of endophytic fungi raru plant Siarang (Cotylelobium melanoxylon) in inhibiting the growth of pathogenic fungi. Pathogenic fungi tested were Collectotrichum, Fusarium oxysporum, Candida albicans and Sclerotium rolfsii. Test antifungal pathogens carried out by using the method of Kirby-Bour, ie by measuring the clear zone located around the paper disc which is the zone of growth inhibition of pathogenic fungi. Measurement of inhibition zone is done by using a caliper or ruler. The results showed that the secondary metabolites of endophytic fungi extracts could inhibit the growth of pathogenic fungus Candida albicans is the clear zone of 10.23 mm. Keywords : endophytic fungus, Cotylelobium melanoxylon, extract of secondary metabolites, fungal pathogens, inhibition zone
Study Productivity And Decomposition Litterfall In Sibolangit Forest, Deli Serdang To Support Field Trip Plantation Ecology
Authors: Sinaga Tonggo 
Published: February 2021

The research was conducted in mountain rain forest of Sibolangit, Deli Serdang, Northen Sumatera. The objectives of this research are to know litter fall productivity, decomposition and litterfall nutrients. Litterfall is the fallen leaves, twigs, flowers and fruits to forest-floor, which one of the input of nutrients to anorganic sril. This input is one of the nutrients cycling to forest ecosystem and the other form atmosfer and a lot of animals. Based on available data on 20 traps, litterfall productivity 5,91 gr/m2/week or 3073,2 kg/ha/year in high topography. Litterfall productivity 4,92gr/m2/week or 2558,4 kg/ha/year in low topography. Litterfall decomposition (lossed of weight) about 25,48% in 30 days ( 1 month ) for meranti ( Shorea sp ) and leaves of Ficus sp had lossed of weight about 8,09% in 30 days ( 1 month ). Ration C/N (Carbon-Nitrogen) litterfall and soil moisture made differrent litterfall decomposition (lossed of weight) Keywords : Productivity, Decomposition, Litterfall, Productivity.
Diversity Bird in Brackish Marsh Muara Tapus Subdistrict Manduamas District Center of Tapanuli Province North Sumatera
Authors: Zuhalmi Anisa , Prastowo Puji 
Published: February 2021

The purposeof this research is to knowdiversity, abundance, dominance and distribution pattern of bird in brackish marsh Muara Tapus Subdistrict Manduamas District Center of Tapanuli. This research was done from February 2015 until April2015. Determination of the station is based on the environmental condition. Total of place observation is 5 places. Every place consist of 4 point with distance 50 m of point accompany. Sampling by concentration point method that is to observe and to take the picture of bird which in every point observation with distance 25 metre for 30 minutes. Time of take sample from 07.00 am – 10.00 am and 04.00 pm – 06.00 pm. The result of this research, found there was 6 orders, 6 family and 8 spesies of birds. Diversity of birds was 0.879, and belonging to the low diversity. The highest abundance of birds was Dendrocygna javanica as many as 110 individual. Average of dominance was 0.512 and belonging to the dominance is moderate. The distribution pattern of birds found in the category of the cluster to 8 species. Keywords: diversity, bird, brackish marsh
Uji Tanin Pada Jenis Rotan-Rotanan Yang Terdapat Di Hutan Aek-Nauli Parapat Kabupaten Simalungun Sumatera Utara
Authors: Husein Rahmad , Edi Syahmi 
Published: February 2021

Penelitian ini bertujuan untuk mengetahui kadar tanin pada rotan di Hutan Penelitian Aek-Nauli Parapat Kabupaten Simalungun berdasarkan ketinggian tempat yang berbeda. Penelitian dilaksanakan selama 3 bulan terhitung mulai bulan Februari 2016 Sampai April 2016. Populasi penelitian ini adalah keseluruhan jenis Rotan yang terdapat di hutan penelitian Aek Nauli Parapat Kabupaten Simalungun Sumatera Utara sedangkan sampel dari penelitian ini adalah keseluruhan jenis Rotan yang berhasil ditemukan dilokasi penelitian tersebut. Penelitian dilakukan dengan survey eksplorasi yang didasarkan pada perbedaan ketinggian (1200 mdpl, 1400 mdpl, dan 1600 mdpl). Hasil penelitian didapatkan 3 jenis Rotan yang terdiri dari Calamus rotang, Plectocomia elongata, Calamus caesius. Uji kadar tanin yang dilakukan pada sampel menunjukkan hasil positif (ada) 1 jenis rotan, yaitu Plectocomia elongate dan Calamus caesius, Calamus rotang tidak positif (tidak ada) menghasilkan senyawa tanin. Melalui pengukuran faktor fisika-kimia diperoleh kelembaban tanah rata-rata sebesar 4,9 %, pH tanah berkisar antara 6,5-6,8, suhu tanah 270 C-280 C, kelembaban udara rata-rata 91%, suhu udara minimum 230C, suhu udara maksimum 240 C, intensitas cahaya matahari 46,85 Candela. Kata Kunci : Metabolit Sekunder, Obat, Tanin
Pemeriksaan Residu Pestisida Pada Tomat (Solanum lycopersicum L.) Di Pasar Tradisional Kota Medan
Authors: Pohan Selvia Dewi 
Published: February 2021

Penelitian tentang pemeriksaan residu pestisida pada tomat (Solanum lycopersicum) di pasar tradisional kota Medan dilakukan dengan tujuan untuk mengetahui jenis-jenis residu pestisida yang terdapat pada tomat dan mengetahui kadar residu pestisida yang terkandung di dalamnya. Penelitian dilakukan dari bulan oktober sampai dengan desember 2015 di Laboratorium Kimia FMIPA Unimed dan Laboratorium PPKS Sumatera Utara. Penelitian ini menggunakan metode observasi, dimana diidentifikasi jenis-jenis residu pestisida yang terdapat pada tomat yang diambil secara acak dari beberapa pasar tradisional di Kota Medan. Pemeriksaan kandungan bahan organik sampel menggunakan alat spectroskopi infrared (SP-IR) dan kemudian kadar residu pestisida sampel dengan kromatografi gas (GC-MS). Hasil penelitian menunjukkan bahwa terdapat 2 jenis residu pestisida pada sampel yang diuji, yaitu klorpirifos dan metidation. Dari hasil pemeriksaan kadar residu pestisida sampel tomat dengan alat kromatografi gas (GC-MS), diketahui bahwa sampel tomat mengandung residu klorpirifos < 0,0085 mg/kg. Hal ini berarti sampel tomat yang diuji mengandung residu pestisida klorpirifos di bawah batas minimum residu (BMR) yang telah ditetapkan Badan Standardisasi Nasional (SNI 7313: 2008) yaitu sebesar 0,5 mg/kg. Kata kunci: identifikasi, jenis, kadar, residu pestisida, tomat, klorpirifos, metidation
Analisis Substrat dan Indeks Keanekaragaman Makrozoobentos di Aliran Sungai Babura Kota Medan
Authors: Berutu Eta Rinayanta , Sinambela Masdiana 
Published: February 2021

Penelitian ini bertujuan untuk mengetahui karakteristik substrat dasar dan indeks keanekaragaman makrozoobentos di aliran sungai Babura kota Medan. Teknik pengumpulan data adalah teknik sampling karena data diperoleh dari hasil pengamatan langsung. Penelitian ini dilakukan bulan Januari 2016, dengan pengambilan sampel pada lima stasiun. Sampel makrozoobentos diambil dengan menggunakan Eckman grab sebanyak lima kali. Makrozoobentos yang ditemukan sebanyak 8 genus yaitu: Pleurocera sp, Anentome sp, Thiara sp, Brotia sp, Melanoides sp, Baetis sp, Haemopis sp, dan Tubifex sp. Indeks keanekaragaman (H’) di sungai Babura tergolong rendah. Hal ini disebabkan oleh tingginya pencemaran yang terjadi di daerah aliran sungai Babura. Karakteristik substrat perairan sungai Babura berupa liat berdebu, lempung berdebu dan lempung berpasir. Dari hasil penelitian didapat bahwa pada stasiun I memiliki keanekaragaman makrozoobentos lebih tinggi dibandingkan stasiun lainnya Kata kunci: Substrat, indeks keanekaragaman, makrozoobentos, Sungai Babura.