bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of dietary vitamin D3 supplementation on the growth performance, tissue Ca and P concentrations, antioxidant capacity, immune response and lipid metabolism in Litopenaeus vannamei larvae
Authors: Dai Tianmeng , Jiao Lefei , Tao Xinyue , Lu Jingjing , Jin Min , Sun Peng , Zhou Qicun 
Published: December 2021

AbstractAn 8-week feeding trial was conducted to investigate the effects of dietary vitamin D3 supplementation on the growth performance, tissue Ca and P concentrations, antioxidant capacity, immune response and lipid metabolism in Litopenaeus vannamei larvae. A total of 720 shrimp (initial weight 0·50 ± 0·01 g) were randomly distributed into six treatments, each of which had three duplicates of forty shrimp per duplicate. Six isonitrogenous and isolipidic diets were formulated to contain graded vitamin D3 (0·18, 0·23, 0·27, 0·48, 0·57 and 0·98 mg/kg of vitamin D3, measured) supplementation levels. The results revealed that L. vannamei fed diet containing 0·48 mg/kg of vitamin D3 achieved the best growth performance. Compared with the control group, supplementing 0·48 mg/kg of vitamin D3 significantly increased (P < 0·05) the activities of catalase, total antioxidative capacity, alkaline phosphatase and acid phosphatase in serum and hepatopancreas. Expression levels of antioxidant and immune-related genes were synchronously increased (P < 0·05). Carapace P and Ca concentrations were increased (P < 0·05) with the increased vitamin D3 supplementation levels. Further analysis of lipid metabolism-related genes expression showed that shrimp fed 0·48 mg of vitamin D3 per kg diet showed the highest value in the expression of lipid synthesis-related genes, while shrimp fed 0·98 mg of vitamin D3 per kg diet showed the highest value in the expression of lipolysis-related genes. In conclusion, the results of present study indicated that dietary supplementation of 0·48 mg/kg of vitamin D3 could increase Ca and P concentrations, improve antioxidant capacity and immune response, and influence lipid metabolism in L. vannamei.
Seaweed and microalgae as major actors of blue biotechnology to achieve plant stimulation and pest and pathogen biocontrol – a review of the latest advances and future prospects
Authors: Berthon Jean-Yves , Michel Thibault , Wauquier Aurélie , Joly Pierre , Gerbore Jonathan , Filaire Edith 
Published: December 2021

AbstractModern agriculture needs proper solutions to face the current trend of pesticides and fertilizers reduction. One of the available leverages to support this transition is the use of bioproducts that are more environmentally friendly and less hazardous for human health. Among them, blue biotechnology and more precisely seaweed and microalgae gain interest every year in the scientific community. In agriculture, seaweeds (Macroalgae) have been used in the production of plant biostimulants while microalgae still remain unexploited. Microalgae are widely described as renewable sources of biofuels, bioingredients and biologically active compounds, such as polyunsaturated fatty acids (PUFAs), carotenoids, phycobiliproteins, sterols, vitamins and polysaccharides, which attract considerable interest in both scientific and industrial communities. They affect agricultural crops for enhancement of plant growth, seedling growth. They can also improve nutrient incorporation, fruit setting, resistance properties against pests and diseases, improving stress management (drought, salinity and temperature). The present review aimed at the interest of blue biotechnology in agronomy, with a specific focus on microalgae, their biological activities and their possible application in agriculture as a potentially sustainable alternative for enhanced crop performance, nutrient uptake and resilience to environmental stress. This review does not only present a comprehensive study of microalgae as plant biostimulants but also as biofertilizers, with a particular emphasis on future challenges these solutions will have to deal with, microalgae being able to synthesize secondary metabolites with potential biopesticidal action.
Understanding the sex inequality in childlessness: an approach using Swedish register data
Authors: Chudnovskaya Margarita , Ueda Peter 
Published: December 2021

AbstractIn most countries, men are more likely to be childless than women. Understanding how this inequality arises is important given the significance of parenthood for individuals’ lives. The objective of this study was to explore how three prominent explanations for sex inequalities in childlessness relate to the Sex Gap in Childlessness (SGC) in Sweden. The three explanations examined were sex ratio imbalance (more men than women), mismeasurement of fatherhood (inequalities in registration) and partnership differences (inequality in multi-partner fertility). Administrative register data for cohorts born in 1945–1974 were used. The population was restricted to men and women who were born in Sweden or arrived prior to the age of 15, and all registered childbearing partnerships were examined. To explore the possible significance of the three explanations, counter-factual standardization was used. Of the three explanations examined, the population sex ratio had the largest positive impact on the SGC, while multi-partner fertility had a negative impact. The results show that inequalities in the sex ratio can explain about 20–34% of the SGC depending on cohort. Inequalities in registration of fathers explain about 9–24% of the SGC depending on cohort. Finally, results show that women are slightly more likely to have multiple partners, and that this behaviour has a substantial minimizing effect on the SGC (minimizing it by 6–65%). To the authors’ knowledge this was the first paper to estimate the scope of the impacts of these three mechanisms on the SGC. Differences in multi-partner fertility have in many instances been used as an explanation for men’s higher childlessness. This study shows that women have slightly more childbearing partners than men, and that this actually leads to a smaller SGC in the studied population.
Lactose-free Dulce de leche: compositional characterization, browning and texture profile
Authors: Pinto Caroline Barroso dos Anjos , Renhe Isis Rodrigues Toledo , Viana Carolina Carvalho Ramos , Perrone Ítalo Tuler , Oliveira Luiz Fernando Cappa de , Stephani Rodrigo 
Published: December 2021

AbstractOur objective was to elaborate lactose-free Dulce de leche (DL) and evaluate the influence of the hydrolysis of this sugar on the attributes of the products. Fluid milk used was divided into two portions and, in one of them, enzymatic hydrolysis of lactose was carried through. Next, the homogenization of milk was performed at 20 MPa. Four different treatments were studied. The final products were evaluated in relation to their composition and physico-chemical characteristics. The main results show that the homogenized lactose-free DL obtained a higher concentration of free 5-Hydroxymethylfurfural (HMF) (133.77 ± 3.42 μmol l−1). Consequently, browning was more intense due to Maillard Reaction. Texture parameters were higher (1611.00 ± 598.78 g hardness and 19.52 ± 2.46 g gumminess) when compared to the homogenized traditional product (28.45 ± 1.16 μmol l−1 free HMF, 437.17 ± 279.3 g hardness, and 406.20 ± 311.69 g gumminess). Lactose-free products are in high demand by consumers; however, the results of this work highlight the challenges to properly control the browning and the texture parameters of DL.
The Endangered giant nuthatch Sitta magna: population size, habitat availability and the implications for its conservation in Thailand
Authors: Khamcha Daphawan , Angkaew Rongrong , Pierce Andrew J. , Gale George A. 
Published: December 2021

AbstractAvailable habitat and hence the global population of the Endangered giant nuthatch Sitta magna, restricted to lower montane habitats of south-western China, eastern Myanmar and northern Thailand, remains poorly quantified. Thailand is the only portion of the species’ range for which there is a population estimate. To obtain a more precise estimate of the Thai population and clarify the extent and characteristics of suitable habitat remaining, we conducted 335 point-count surveys at 67 points across eight localities during November 2019–February 2020. We estimated abundance and identified preferred habitat characteristics using N-mixture models, and created suitable habitat maps based on data from surveys and remote sensing. Our estimate for Thailand was 578 (95% CI 391–854) individuals based on a density of 3.7 (95% CI 2.5–5.5) individuals/km2 in 156 km2 of suitable habitat. The giant nuthatch prefers dry forest with a large amount of mature native or planted pine Pinus kesiya and with a large tree basal area and an open canopy. Our estimate of suitable habitat remaining was less than previously reported and thus the population has probably decreased, although most of this habitat is within protected areas. Habitats for the species in Thailand have a stronger level of protection than in Myanmar and China, although habitat in China remains unquantified. We recommend further research in Myanmar and China, which may hold the majority of available habitat for the giant nuthatch. For long-term management, detailed study of the association of the giant nuthatch with pine plantations is required.
The impact of the COVID-19 pandemic on depression in community-dwelling older adults: a prospective cohort study
Authors: Oh Dae Jong , Yang Hee Won , Suh Seung Wan , Byun Seonjeong , Kim Tae Hui , Kwak Kyung Phil , Kim Bong Jo , Kim Shin Gyeom , Kim Jeong Lan , Moon Seok Woo , Park Joon Hyuk , Ryu Seung-Ho , Lee Dong Woo , Lee Seok Bum , Lee Jung Jae , Jhoo Jin Hyeong , Bae Jong Bin , Han Ji Won , Kim Ki Woong 
Published: December 2021

AbstractBackgroundThere are growing concerns about the impact of the COVID-19 pandemic on the mental health of older adults. We examined the effect of the pandemic on the risk of depression in older adults.MethodsWe analyzed data from the prospective cohort study of Korean older adults, which has been followed every 2 years. Among the 2308 participants who completed both the third and the fourth follow-up assessments, 58.4% completed their fourth follow-up before the outbreak of COVID-19 and the rest completed it during the pandemic. We conducted face-to-face diagnostic interviews using Mini International Neuropsychiatric Interview and used Geriatric Depression Scale. We performed generalized estimating equations and logistic regression analyses.ResultsThe COVID-19 pandemic was associated with increased depressive symptoms in older adults [b (standard error) = 0.42 (0.20), p = 0.040] and a doubling of the risk for incident depressive disorder even in euthymic older adults without a history of depression (odds ratio = 2.44, 95% confidence interval 1.18–5.02, p = 0.016). Less social activities, which was associated with the risk of depressive disorder before the pandemic, was not associated with the risk of depressive disorder during the pandemic. However, less family gatherings, which was not associated with the risk of depressive disorder before the pandemic, was associated with the doubled risk of depressive disorder during the pandemic.ConclusionsThe COVID-19 pandemic significantly influences the risk of late-life depression in the community. Older adults with a lack of family gatherings may be particularly vulnerable.
Effects of free-flight activities on wildlife: a poorly understood issue in conservation
Authors: Tobajas Jorge , Guil Francisco , Margalida Antoni 
Published: December 2021

SummaryRecreational activities may have negative effects on wildlife, but there are very few studies specifically on the effects of free-flight activities (i.e., hang-gliders, paragliders and their powered derivatives) on wildlife. We review the existing scientific studies on this issue in order to identify the gaps in knowledge at the taxonomic-group level in order to develop guidelines to minimize the impacts of recreational free-flight on wildlife. We found that studies mainly concerned the effects on four ungulate species (chamois, red deer, roe deer and Alpine ibex) and, to a lesser extent, on raptors such as the golden eagle and two vulture species (bearded vulture and cinereous vulture). The studies have generally been carried out in high mountain areas (e.g., the European Alps). Data show that free-flight activities create disturbances and have negative effects on wildlife, resulting in increased energy expenditure, reduction of feeding time, abandonment of feeding areas, reduced breeding output, loss of body condition, increased predation risk and harm from flight accidents. However, the lack of studies on many species and areas, along with the small number of long-term studies, prevents proper assessment of the current situation regarding the impact of this activity on wildlife. We provide recommendations to improve the regulation of this activity.
Nomogram prediction of severe risk in patients with COVID-19 pneumonia
Authors: Tang Wei , Yao Run , Zheng Fang , Huang Yaxiong , Zhou Guoqiang , Chen Ruochan , Li Ning 
Published: December 2021

Abstract
Coronavirus disease-2019 (COVID-19) elicits a range of different responses in patients and can manifest into mild to very severe cases in different individuals, depending on many factors. We aimed to establish a prediction model of severe risk in COVID-19 patients, to help clinicians achieve early prevention, intervention and aid them in choosing effective therapeutic strategy. We selected confirmed COVID-19 patients who were admitted to First Hospital of Changsha city between 29 January and 15 February 2020 and collected their clinical data. Multivariate logical regression was used to identify the factors associated with severe risk. These factors were incorporated into the nomogram to establish the model. The ROC curve, calibration plot and decision curve were used to assess the performance of the model. A total of 228 patients were enrolled and 33 (14.47%) patients developed severe pneumonia. Univariate and multivariate analysis showed that shortness of breath, fatigue, creatine kinase, lymphocytes and h CRP were independent factors for severe risk in COVID-19 patients. Incorporating age, chronic obstructive pulmonary disease (COPD) and these factors, the nomogram achieved good concordance indexes of 0.89 [95% confidence interval (CI) 0.832–0.949] and well-fitted calibration plot curves (Hosmer–Lemeshow test: P = 0.97). The model provided superior net benefit when clinical decision thresholds were between 15% and 85% predicted risk. Using the model, clinicians can intervene early, improve therapeutic effects and reduce the severity of COVID-19, thus ensuring more targeted and efficient use of medical resources.
Race, homelessness and inner-city policy in 1980s Britain
Authors: Child Phil 
Published: December 2021

AbstractThis article utilizes an organizational history of the Birmingham-based Handsworth Single Homeless Action Group (HSHAG) to explore black youth homelessness and inner-city policy in 1980s Britain. It draws upon under-used charity archives to intervene in recent debates, considering the part played by the voluntary sector within the Thatcher administrations’ inner-city policies and what targeted funding of this kind reveals about the remaking of the welfare state in these years. First, it introduces HSHAG, setting out the context of inner-city funding programmes, before questioning how sustainable this might have been for voluntary organizations engaged in supporting the homeless population. Secondly, it examines the effects of housing privatization and unemployment on HSHAG's attempts to advise homeless black individuals and assert their rights as citizens to state support. Together, it exposes the role of the voluntary sector in welfare state restructuring and considers how this change made the task of homelessness organizations Herculean.
Cardiac outcomes in severe acute respiratory syndrome coronavirus-2-associated multisystem inflammatory syndrome at a tertiary paediatric hospital
Authors: Kucera Filip , Laurence Craig , Simmonds Jacob , Gavela Javier , Bodnar Tetyana , Brogan Paul , Hoskote Aparna , Skellett Sophie , Moshal Karyn , Bamford Alasdair , Khambadkone Sachin 
Published: December 2021

AbstractIntroduction:We describe a cohort of children referred with multisystem inflammatory syndrome in children associated with severe acute respiratory syndrome coronavirus 2 and compare this cohort with a 2019 cohort of children with Kawasaki disease.Methods:We conducted a retrospective cohort study of 2019 and 2020 referrals to the inflammatory cardiology service at Great Ormond Street Hospital for Children. We compared cardiac and inflammatory parameters of a sub-section of the 2020 cohort who presented with reduced left ventricular ejection fraction with the remainder of the cohort.Results:Referrals significantly increased between February and June 2020 compared to 2019 (19.8/30 days versus 3.9/30 days). Frequency of coronary artery aneurysms (11/79 (13.9%) versus 7/47 (14.9%)) or severe coronary artery aneurysms (6/79 (7.6%) versus 3/47 (6.4%)) was similar between 2020 and 2019, respectively. The 2020 cohort was older (median age 9.07 years versus 2.38 years), more likely to be of Black, Asian, or other minority ethnic group (60/76 (78.9%) versus 25/42 (59.5%)), and more likely to require inotropic support (22 (27.5%) versus 0 (0%)). Even children with significantly reduced left ventricular ejection fraction demonstrated complete recovery of cardiac function within 10 days (mean 5.25 days ± 2.7).Discussion:We observed complete recovery of myocardial dysfunction and an overall low rate of permanent coronary sequelae, indicating that the majority of children with multisystem inflammatory syndrome in children are unlikely to encounter long-term cardiac morbidity. Although the frequency of myocardial dysfunction and inotropic support requirement is not consistent with a diagnosis of Kawasaki disease, the frequency of coronary artery abnormalities and severe coronary artery abnormalities suggests a degree of phenotypic overlap.
Was the COVID-19 Pandemic Associated with Gender Disparities in Authorship of Manuscripts Submitted to Clinical Neuropsychology Journals?
Authors: Babicz Michelle A. , Matchanova Anastasia , Broomfield Robiann , DesRuisseaux Libby A. , Gereau Michelle M. , Brothers Stacey L. , Radigan Lauren , Porter Erik , Lee Gregory P. , Rapport Lisa J. , Suchy Yana , Yeates Keith Owen , Woods Steven Paul 
Published: December 2021

AbstractObjective:The COVID-19 pandemic exacerbated gender disparities in some academic disciplines. This study examined the association of the pandemic with gender authorship disparities in clinical neuropsychology (CN) journals.Method:Author bylines of 1,018 initial manuscript submissions to four major CN journals from March 15 through September 15 of both 2019 and 2020 were coded for binary gender. Additionally, authorship of 40 articles published on pandemic-related topics (COVID-19, teleneuropsychology) across nine CN journals were coded for binary gender.Results:Initial submissions to these four CN journals increased during the pandemic (+27.2%), with comparable increases in total number of authors coded as either women (+23.0%) or men (+25.4%). Neither the average percentage of women on manuscript bylines nor the proportion of women who were lead and/or corresponding authors differed significantly across time. Moreover, the representation of women as authors of pandemic-related articles did not differ from expected frequencies in the field.Conclusions:Findings suggest that representation of women as authors of peer-reviewed manuscript submissions to some CN journals did not change during the initial months of the COVID-19 pandemic. Future studies might examine how risk and protective factors may have influenced individual differences in scientific productivity during the pandemic.
Comparison of preoperative chemoradiation with radiation or chemotherapy alone in patients with non-metastatic, resectable retroperitoneal sarcoma
Authors: Ma Sung Jun , Yu Brian , Serra Lucas M. , Bartl Austin J. , Oladeru Oluwadamilola T. , Farrugia Mark , Shekher Rohil , Iovoli Austin J. , Fekrmandi Fatemeh , Yu Han , Singh Anurag K. 
Published: December 2021

Abstract

Aim:
Optimal preoperative therapy regimen in the treatment of resectable retroperitoneal sarcoma (RPS) remains unclear. This study compares the impact of preoperative radiation, chemoradiation and chemotherapy on overall survival (OS) in RPS patients.

Materials and Methods:
The National Cancer Database (NCDB) was queried for patients with non-metastatic, resectable RPS (2006–15). The primary endpoint was OS, evaluated by Kaplan–Meier method, log-rank test, Cox multivariable analysis and propensity score matching.

Results:
A total of 1,253 patients met the inclusion criteria, with 210 patients (17%) receiving chemoradiation, 850 patients (68%) receiving radiation and 193 patients (15%) receiving chemotherapy. On Cox multivariable analysis, when compared to preoperative chemoradiation, preoperative radiation was not associated with improved OS (hazards ratio [HR] 0·98, 95% CI 0·76–1·25, p = 0·84), while preoperative chemotherapy was associated with worse OS (HR 1·64, 95% CI 1·24–2·18, p < 0·001). Similar findings were observed in 199 and 128 matched pairs for preoperative radiation and chemotherapy, respectively, when compared to preoperative chemoradiation.

Findings:
Our study suggested an OS benefit in using preoperative chemoradiation compared to chemotherapy alone, but OS outcomes were comparable between preoperative chemoradiation and radiation alone.
Lebensraum’s Tropical Turn
Authors: Vickerman Milton 
Published: December 2021

AbstractIn 1981 the ATF, FBI, and U.S. Customs Service agents arrested a group of American and Canadian White nationalists as they were on their way to overthrow the government of Dominica. Although seemingly improbable, the event is important because it illustrates the hegemonic nature of the relationship between the United States and Caribbean countries and, also, the globalization of White nationalist violence. In this paper I show that extant theory on White nationalism can be used to explain the White nationalist plot. In particular, I invoke the concept ofLebensraumand the fact that White nationalists espouse multiple objectives—in addition to racism—to explain their intent to subvert a Black country and to live there.
Improving Atmospheric Angular Momentum Forecasts by Machine Learning
Authors: Dill R. , Saynisch‐Wagner J. , Irrgang C. , Thomas M. 
Published: December 2021

AbstractEarth angular momentum forecasts are naturally accompanied by forecast errors that typically grow with increasing forecast length. In contrast to this behavior, we have detected large quasi‐periodic deviations between atmospheric angular momentum wind term forecasts and their subsequently available analysis. The respective errors are not random and have some hard to define yet clearly visible characteristics which may help to separate them from the true forecast information. These kinds of problems, which should be automated but involve some adaptation and decision‐making in the process, are most suitable for machine learning methods. Consequently, we propose and apply a neural network to the task of removing the detected artificial forecast errors. We found that a cascading forward neural network model performed best in this problem. A total error reduction with respect to the unaltered forecasts amounts to about 30% integrated over a 6‐days forecast period. Integrated over the initial 3‐days forecast period, in which the largest artificial errors are present, the improvements amount to about 50%. After the application of the neural network, the remaining error distribution shows the expected growth with forecast length. However, a 24‐hourly modulation and an initial baseline error of 2 × 10−8 became evident that were hidden before under the larger forecast error.