bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hospitalisations for falls and hip fractures attributable to vitamin D deficiency in older Australians
Authors: Neale Rachel E. , Wilson Louise F. , Black Lucinda J. , Waterhouse Mary , Lucas Robyn M. , Gordon Louisa G. 
Published: January 2021

AbstractVitamin D deficiency is associated with an increased risk of falls and fractures. Assuming this association is causal, we aimed to identify the number and proportion of hospitalisations for falls and hip fractures attributable to vitamin D deficiency (25 hydroxy D (25(OH)D) <50 nmol/l) in Australians aged ≥65 years. We used 25(OH)D data from the 2011/12 Australian Health Survey and relative risks from published meta-analyses to calculate population-attributable fractions for falls and hip fracture. We applied these to data published by the Australian Institute of Health and Welfare to calculate the number of events each year attributable to vitamin D deficiency. In men and women combined, 8·3 % of hospitalisations for falls (7991 events) and almost 8 % of hospitalisations for hip fractures (1315 events) were attributable to vitamin D deficiency. These findings suggest that, even in a sunny country such as Australia, vitamin D deficiency contributes to a considerable number of hospitalisations as a consequence of falls and for treatment of hip fracture in older Australians; in countries where the prevalence of vitamin D deficiency is higher, the impact will be even greater. It is important to mitigate vitamin D deficiency, but whether this should occur through supplementation or increased sun exposure needs consideration of the benefits, harms, practicalities and costs of both approaches.
The foreign language effect in bilingualism: Examining prosocial sentiment after offense taking
Authors: Miller David , Solis-Barroso Cecilia , Delgado Rodrigo 
Published: January 2021

AbstractThis study examines whether theforeign language effectmitigates reactions to value-inconsistent sociopolitical content. We examined 69 English–Spanish bilinguals and 31 Spanish–English heritage bilinguals, half of whom did the experiment in their native language and half in their second language. Participants were administered a survey in which trial emotiveness was manipulated by using the quantifiers some and all (e.g.,Some Trump supporters are racistsvs.All Trump supporters are racists). The some-types (n= 30) served as a baseline for the all-types (n= 30). After each target, participants rated their willingness to be prosocial (e.g., holding the door for a stranger) on a scale of 1–7, 1 beingtotally agreeand 7 beingtotally disagree. Our results suggest that processing emotional information in a second language is less emotional than in a first language and that such a decrease in emotionality results in the neutralization of offense taken. However, individual differences in linguistic profiles across participants, as well as contextual framing, lead to discrete value judgments. Proficiency, learner type, political affiliation, and context type affect willingness to engage in prosocial behavior. As a group, the bilinguals showed no decrease in their willingness to engage in such behaviors, regardless of context type; speakers of higher proficiency and stronger political values increase prosocial sentiment; and lower proficiency and weaker views lead to neutral prosocial sentiment.
Reconnecting to others: grounded theory of social functioning following age-related hearing loss
Authors: Fowler Elizabeth , Woodside Jayne V. , Kee Frank , Loughrey David , Lawlor Brian , McHugh Power Joanna 
Published: January 2021

AbstractAge-related hearing loss (ARHL) is common and a known risk factor for social disengagement in later life. This study explored social functioning following a diagnosis of ARHL. Using a constructivist grounded theory approach we developed an interview schedule to advance a grounded theory from data collected from six older adults who used either hearing aids or cochlear implants. Interview questions concerned social functioning as well as focusing on their perspective of the impact of ARHL on cognitive functioning. We describe a grounded theory conceived as ‘Reconnecting to Others’. This theory posits that participants faced social challenges in relation to their ARHL, and resolved these challenges partly through the use of hearing aids and cochlear implantation. The theory also emphasises the importance of help from other hearing aid users for new users, and corroborates prior findings about strategies older adults with ARHL use to cope with their hearing impairment in various social situations. Once hearing aids and cochlear implants are used and adapted to with the help of peers, participants completed their journey by helping others who had received diagnoses of ARHL. Additionally, participants spoke of the pleasure of hearing again. Interestingly, no participant felt that their ARHL had impacted their cognitive functioning. Our theory provides a basis for explaining existing quantitative findings as well as creating new hypotheses for future testing.
Determinants of Managed Entry Agreements in the context of Health Technology Assessment: a comparative analysis of oncology therapies in four countries
Authors: Efthymiadou Olina , Kanavos Panos 
Published: January 2021

Abstract

Background
Managed Entry Agreements (MEAs) are increasingly used to address uncertainties arising in the Health Technology Assessment (HTA) process due to immature evidence of new, high-cost medicines on their real-world performance and cost-effectiveness. The literature remains inconclusive on the HTA decision-making factors that influence the utilization of MEAs. We aimed to assess if the uptake of MEAs differs between countries and if so, to understand which HTA decision-making criteria play a role in determining such differences.

Methods
All oncology medicines approved since 2009 in Australia, England, Scotland, and Sweden were studied. Four categories of variables were collected from publicly available HTA reports of the above drugs: (i) Social Value Judgments (SVJs), (ii) Clinical/Economic evidence submitted, (iii) Interpretation of this evidence, and (iv) Funding decision. Conditional/restricted decisions were coded as Listed With Conditions (LWC) other than an MEA or LWC including an MEA (LWCMEA). Cohen's κ-scores measured the inter-rater agreement of countries on their LWCMEA outcomes and Pearson's chi-squared tests explored the association between HTA variables and LWCMEA outcomes.

Results
A total of 74 drug-indication pairs were found resulting in n = 296 observations; 8 percent (n = 23) were LWC and 55 percent (n = 163) were LWCMEA. A poor-to-moderate agreement existed between countries (−.29 < κ < .33) on LWCMEA decisions. Cross-country differences within the LWCMEA sample were partly driven by economic uncertainties and largely driven by SVJs considered across agencies.

Conclusions
A set of HTA-related variables driving the uptake of MEAs across countries was identified. These findings can be useful in future research aimed at informing country-specific, “best-practice” guidelines for successful MEA implementation.
Epidemiology of COVID-19 in Northern Ireland, 26 February 2020–26 April 2020
Authors: Pett J. , McAleavey P. , McGurnaghan P. , Spiers R. , O'Doherty M. , Patterson L. , Johnston J. 
Published: January 2021

AbstractThis paper describes the epidemiology of coronavirus disease 2019 (COVID-19) in Northern Ireland (NI) between 26 February 2020 and 26 April 2020, and analyses enhanced surveillance and contact tracing data collected between 26 February 2020 and 13 March 2020 to estimate secondary attack rates (SAR) and relative risk of infection among different categories of contacts of individuals with laboratory confirmed severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection. Our results show that during the study period COVID-19 cumulative incidence and mortality was lower in NI than the rest of the UK. Incidence and mortality were also lower than in the Republic of Ireland (ROI), although these observed differences are difficult to interpret given considerable differences in testing and surveillance between the two nations. SAR among household contacts was 15.9% (95% CI 6.6%–30.1%), over 6 times higher than the SAR among ‘high-risk’ contacts at 2.5% (95% CI 0.9%–5.4%). The results from logistic regression analysis of testing data on contacts of laboratory-confirmed cases show that household contacts had 11.0 times higher odds (aOR: 11.0, 95% CI 1.7–70.03,P-value: 0.011) of testing positive for SARS-CoV-2 compared to other categories of contacts. These results demonstrate the importance of the household as a locus of SARS-CoV-2 transmission, and the urgency of identifying effective interventions to reduce household transmission.
Not by equations alone: Reasoning with extensible effects
Authors: KISELYOV OLEG , MU SHIN-CHENG , SABRY AMR 
Published: January 2021

Abstract
The challenge of reasoning about programs with (multiple) effects such as mutation, jumps, or IO dates back to the inception of program semantics in the works of Strachey and Landin. Using monads to represent individual effects and the associated equational laws to reason about them proved exceptionally effective. Even then it is not always clear what laws are to be associated with a monad—for a good reason, as we show for non-determinism. Combining expressions using different effects brings challenges not just for monads, which do not compose, but also for equational reasoning: the interaction of effects may invalidate their individual laws, as well as induce emerging properties that are not apparent in the semantics of individual effects. Overall, the problems are judging the adequacy of a law; determining if or when a law continues to hold upon addition of new effects; and obtaining and easily verifying emergent laws.
We present a solution relying on the framework of (algebraic, extensible) effects, which already proved itself for writing programs with multiple effects. Equipped with a fairly conventional denotational semantics, this framework turns useful, as we demonstrate, also for reasoning about and optimizing programs with multiple interacting effects. Unlike the conventional approach, equational laws are not imposed on programs/effect handlers, but induced from them: our starting point hence is a program (model), whose denotational semantics, besides being used directly, suggests and justifies equational laws and clarifies side conditions. The main technical result is the introduction of the notion of equivalence modulo handlers (“modulo observation”) or a particular combination of handlers—and proving it to be a congruence. It is hence usable for reasoning in any context, not just evaluation contexts—provided particular conditions are met.
Concretely, we describe several realistic handlers for non-determinism and elucidate their laws (some of which hold in the presence of any other effect). We demonstrate appropriate equational laws of non-determinism in the presence of global state, which have been a challenge to state and prove before.
Triposes as a generalization of localic geometric morphisms
Authors: Frey Jonas , Streicher Thomas 
Published: January 2021

AbstractIn Hyland et al. (1980), Hyland, Johnstone and Pitts introduced the notion of tripos for the purpose of organizing the construction of realizability toposes in a way that generalizes the construction of localic toposes from complete Heyting algebras. In Pitts (2002), one finds a generalization of this notion eliminating an unnecessary assumption of Hyland et al. (1980). The aim of this paper is to characterize triposes over a base topos ${\cal S}$ in terms of so-called constant objects functors from ${\cal S}$ to some elementary topos. Our characterization is slightly different from the one in Pitts’s PhD Thesis (Pitts, 1981) and motivated by the fibered view of geometric morphisms as described in Streicher (2020). In particular, we discuss the question whether triposes over Set giving rise to equivalent toposes are already equivalent as triposes.
Search for high-redshift blazars with Fermi-LAT
Authors: Kreter Michael 
Published: January 2021

AbstarctHigh-redshift blazars (z ⩾ 2.5) are one of the most powerful classes of gamma-ray sources in the Universe. These objects posses the highest jet powers and luminosities and have black-hole masses often in excess of 109 solar masses. In addition, high-redshift blazars are important cosmological probes and serve as test objects for blazar evolution models. Due to their large distance, their high-energy emission peak is downshifted to energies below the GeV range, which makes them difficult to study with Fermi/LAT and only the very brightest objects are detectable. Hence, only a small number of high-redshift blazars could be detected with Fermi/LAT so far. In this work, we present a strategy to significantly increase the detection statistics at redshift z ⩾ 2.5 via a search for flaring events in high-redshift gamma-ray blazars whose long-term flux remains below the sensitivity limit of Fermi/LAT. Seven previously GeV undetected high-redshift blazars have been identified from their bright monthly outburst periods, while more detections are expected in the future.
Panchromatic characterisation of accreting black holes in dusty star-forming galaxies
Authors: Rivera Gabriela Calistro 
Published: January 2021

AbstractAlthough AGN do not typically dominate the bolometric emission of dusty star forming galaxies, large AGN fractions (sometimes > 40%) have been observed in various sub-millimeter surveys. These diagnostics have been however mostly based on X-ray counterpart selections and a complete multiwavength census of the fraction of AGN hosts is needed. I will present new advances in the modelling of panchromatic spectral energy distributions (SEDs) of active galactic nuclei (AGN), based on our publicly available code AGNfitter (Calistro-Rivera et al.2016). AGNfitter implements a fully Bayesian Markov Chain Monte Carlo method to fit the spectral energy distributions of AGNs pushing the wavelengths frontiers from the radio to the X-rays. I will present a recent application of AGNfitter on dusty star forming galaxies in the ALESS submillimeter survey to obtain an unbiased multiwavelength characterisation of the nuclear activity buried in dusty star formation. Our method reveals a significantly larger contribution of AGN activity to the emission in these galaxies than previously observed based on X-rays diagnostics. Our method represents a unique tool to potentially characterise an unbiased accretion history of the Universe when applied to larger populations of star-forming galaxies.
AGN types and unification model
Authors: Spinoglio Luigi , Fernández-Ontiveros Juan Antonio 
Published: January 2021

AbstractThe motivation of the “unified model” is to explain the main properties of the large zoo of active galactic nuclei with a single physical object. The discovery of broad permitted lines in the polarized spectrum of type 2 Seyfert galaxies in the mid 80’s led to the idea of an obscuring torus, whose orientation with respect to our line of sight was the reason of the different optical spectra. However, after many years of observations with different techniques, including IR and mm interferometry, the resulting properties of the observed dust structures differ from the torus model that would be needed to explain the type 1 vs type 2 dichotomy. Moreover, in the last years, multi-frequency monitoring of active galactic nuclei has shown an increasing number of transitions from one type to the other one, which cannot be explained in terms of the simple orientation of the dusty structure surrounding the active galactic nucleus (AGN). The interrelations between the AGN and the host galaxy, as also shown in the Magorrian relation, suggest that the evolution of the host galaxy may also have an important role in the observed manifestation of the nuclei. As an example, the observed delay between the maximum star formation activity and the onset of the AGN activity, and the higher occurrence of type 2 nuclei in star forming galaxies, have suggested the possible evolutionary path from, e.g., H II → AGN2 → AGN1. In the next years the models of unification need to also consider this observational framework and not only simple orientation effects.
Predicting the emission profile and estimation of model parameters for some nearby LLAGN using accretion and jet models
Authors: Bandyopadhyay Bidisha , Xie Fu-Guo , Nagar Neil M. , Schleicher Dominik R. G. , Ramakrishnan Venkatessh , Arévalo Patricia , López Elena , Diaz Yaherlyn 
Published: January 2021

AbstractThe Event Horizon Telescope (EHT) provides a unique opportunity to probe the physics of supermassive black holes through Very Large Baseline Interferometry (VLBI), such as the existence of the event horizon, the accretion processes as well as jet formation in Low Luminosity AGN (LLAGN). We build a theoretical model which includes an Advection Dominated Accretion Flow (ADAF) and a simple radio jet outflow. The predicted spectral energy distribution (SED) of this model can be compared to observations to get the best estimates of the model parameters. The model-predicted radial emission profiles at different frequency bands can be used to predict whether the inflow can be resolved by the EHT or other telescopes. We have applied this method to some nearby LLAGN such as M84, NGC 4594, NGC 4278 and NGC 3998. We also estimate the model parameters for each of them using high resolution data from different surveys.
The role of failed accretion disk winds in active galactic nuclei
Authors: Giustini Margherita , Proga Daniel 
Published: January 2021

AbstractBoth observational and theoretical evidence point at outflows originating from accretion disks as fundamental ingredients of active galactic nuclei (AGN). These outflows can have more than one component, for example an unbound supersonic wind and a failed wind (FW). The latter is a prediction of the simulations of radiation-driven disk outflows which show that the former is accompanied by an inner failed component, where the flow struggles to escape from the strong gravitational pull of the supermassive black hole. This FW component could provide a physical framework to interpret various phenomenological components of AGN. Here we briefly discuss a few of them: the broad line region, the X-ray obscurer, and the X-ray corona.
Elusive accretion discs in low luminosity AGN
Authors: Almudena Prieto M. , Fernandez-Ontiveros Juan A. 
Published: January 2021

AbstractLow luminosity AGN represent the vast majority of the AGN population in the near universe, and still the least conforming class with the standard AGN scenario. Their low luminosity is at odds with their often very high black hole masses and powerful jets. I will review the challenges that parsec-scale observations across the electromagnetic spectrum of some of the nearest ones are opening on the true nature of their emission, their transition from the most luminous to the feeble ones, and their accretion power. The strict limits imposed by these observations on their accretion power are confronted with the high mechanical energy inferred for their jets. Possible scenarios for these nuclei including the extraction of power form the black hole spin are discussed (Prieto et al. 2016; Fernandez-Ontiveros et al. 2019).
Properties of green valley galaxies in relation to their selection criteria
Authors: Nyiransengiyumva Beatrice , Pović Mirjana , Nkundabakura Pheneas , Mahoro Antoine 
Published: January 2021

AbstractThe distribution of galaxies has been studied to show the difference between the blue cloud and red sequence and to define the green valley region. However, there are still many open questions regarding the importance of the green valley for understanding the morphological transformation and evolution of galaxies, how galaxies change from late-type to early-type and the role of AGN in galaxy formation and evolution scenario. The work focused on studying in more details the properties of green valley galaxies by testing the six most used selection criteria, differences between them, and how they may affect the main results and conclusions. The main findings are that, by selecting the green valley galaxies using different criteria, we are selecting different types of galaxies in terms of their stellar masses, sSFR, SFR, spectroscopic classification and morphological properties, where the difference was more significant for colour criteria than for sSFR and SFR vs. M* criteria.
Quasar host galaxies and environments in the GAMA survey
Authors: Kotilainen Jari 
Published: January 2021

AbstractWe present first results from our study of the host galaxies and environments of quasars in Galaxy And Mass Assembly (GAMA), a multiwavelength photometric and spectroscopic survey for ∼300,000 galaxies over ∼300 deg2, to a limiting magnitude of r ∼ 20 mag. We use a GAIA-selected sample of ∼350 quasars at z < 0.3 in GAMA. For all the quasars, we determine all surrounding GAMA galaxies and measure their star formation (SF) rate and SF history, and the host galaxy morphology and group membership of the quasars. As a comparison sample of inactive galaxies, we use 1000 subsets of galaxies in GAMA, matched in redshift and galaxy stellar mass to the quasars. We find that quasar activity does not depend on the large-scale environment (cluster/group/void), although quasars tend to prefer satellite location in their environment. Compared to inactive galaxies, quasars are preferentially hosted in bulge-dominated galaxies and have higher SF rates, both overall and averaged over the last 10 and 100 Myr. Quasars also have shorter median SF timescales, shorter median time since the last SF burst, and higher metallicity than inactive galaxies. We discuss these results in terms of triggering mechanisms of the quasar activity and the role of quasars in galaxy evolution.
The impact of AGN on the life of their host galaxies at z ∼ 2
Authors: Circosta Chiara 
Published: January 2021

AbstractFeedback from active galactic nuclei (AGN) is thought to be key in shaping the life cycle of host galaxies by regulating star formation. Therefore, measuring the molecular gas reservoir out of which stars form is essential to understand the impact of AGN on star formation. In this talk I present an ongoing analysis to study the CO(J = 3−2) emission in a sample of 25 AGN at z ∼ 2 using ALMA observations. The CO properties of our AGN have been compared to normal (non-AGN) star-forming galaxies. The comparison between the two samples reveals that, on average, the CO luminosities of AGN at high stellar masses (log(M*/M⊙) > 11) are 0.5 dex lower than normal galaxies. We ascribe this difference to the AGN activity, which could be able to change the conditions of the gas through, e.g., excitation, heating or removal of CO.