bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pensamiento incaico: Wiracocha
Authors: Rivara de Tuesta María Luisa 
Published: April 2021

Esta identificación porta en sí el primer problema para el estudio de Wiracocha; debemos por lo tanto despojarlo cuidadosamente, en la versión del cronista cristiano, del ropaje interpretativo, ya que nuestro propósito está encaminado a desentrañar su sentido y significación en forma objetiva. Examina primero la forma mitológica, luego la poemática; nos ocuparemos igualmente de las diferentes modalidades de su significación en la traducción al código occidental, para llegar en última instancia a nuestra interpretación acerca de cuál fue su sentido y significación
La doctrina no escrita de Platón según H. J . Krämer
Authors: Sobrevilla David 
Published: April 2021

La redacción final de este trabajo fue posibilitada por una beca de la Fundación Alexander von Humboldt. Agradecemos al Prof. H. J. Krämer la ayuda bibliográfica que nos facilitó para escribirlo. Desconocemos la publicación de este artículo en Logos (México: N°. 30, 1982; pp. 11-47) por sus numerosísimas erratas y por sus cambios inconsultos de estilo.
Experience in use of L­-carnitine in treatment of patients with epidermolysis bullosa
Authors: Rakhmatov A.B. , Khaldarbekov M.K. 
Published: April 2021

Objective — to study the effectiveness of L-carnitine in patients with various forms of congenital epidermolysis bullosa (CEB).Materials and methods. We observed 120 patients with CEB aged 1 to 12 years. A simple form of the disease was diagnosed in 60, dystrophic form — in 60 children. According to genealogical maps, 17 (28.3 %) of 60 patients with dystrophic CEB had an autosomal dominant type of inheritance, and 43 (71.7 %) of 60 had autosomal recessive inheritance. In the autosomal dominant type, the multiple blisters, miliums and atrophic scarrings, mainly on the extremities, as well as anonychias were dominant as clinical manifestations. In the autosomal recessive type, multiple blisters, erosions, crusts, atrophic scars, onychodystrophy, pseudosyndactylies on the upper and lower extremities, as well as disabling contractures of the hands, feet, elbows and knees were observed.L-carnitine at a dose of 1 ml/kg during 3 months was prescribed as part of the complex therapy to patients with CEB. The standard treatment for patients with CEB was the correct use of external means and dressings to reduce trauma to the foci and accelerate the epithelialization of erosive rashes.Results and discussion. For clinical evaluation of the efficacy of L-carnitine, patients with CEB were divided into groups comparable by sex, age, duration and form of the disease: group I consisted of 30 patients with simple CEB who received standard treatment, group II — of 30 patients with simple CEB who received standard treatment in combination with L-carnitine, group III — of 30 patients with dystrophic form of CEB who received standard treatment, group IV — of 30 patients with dystrophic form of CEB who received standard treatment in combination with L-carnitine. The positive result of therapy (epithelialization of erosions and the absence of new rashes) was achieved in 19 (63.3 %) of 30 patients of group I, in 26 (86.7 %) of 30 patients of group II, in 11 (36.7 %) of 30 patients of group III, in 16 (53.3 %) of 30 patients of group IV. This confirms the effectiveness and feasibility of using L-carnitine in various forms of CEB.Conclusions. The use of L-carnitine in the complex therapy of patients with CEB allows accelerating the epithelialization of erosive formations on the skin and visible mucous membranes.
Optimasi Biaya Pengiriman Buah Kelapa Sawit (Studi Kasus PT. Agro Muko)
Authors: Murgani Ramli 
Published: April 2021

<p>PT. Agro Muko adalah perusahaan perkebunan kelapa sawit dan melakukan pengiriman buah kelapa sawit dari perkebunan di tiga tempat yaitu Talang Petai Estate, Sei Kiang Estate, dan Tanah Rekah Estate. Dari ketiga lokasi ini akan melakukan pengiriman buah kelapa sawit ke beberapa pabrik yaitu, Muko-Muko, Bunga Tanjung, Air Bikuk, dan Air Hitam.Pengiriman buah kelapa sawit menggunakan alat transportasi darat berupa truk-truk terbuka dengan kapasitas pengiriman 7,5 ton. Frekuensi pengiriman menjadi hal yang penting perhitungan biaya transportasi dengan daya tampung pabrik yang terbatas. Biaya pengiriman akan disesuaikan dengan jumlah kapasitasnya dimana untuk pengiriman diatas kapasitas akan dihitung dan sisanya dihitung satu kali pengiriman sebagai biaya tambahan. Hasil perhitungan langsung biaya transportasi dari 3 kebun ke 4 pabrik adalah Rp.51.392.000,-Dengan metode <em>Northwest Corner</em> (NWC) diperoleh Rp.48.597.000,- dan solusi optimal <em>modified distribution method</em> (MODI)Rp.48.597.000,-.<em>Output</em> aplikasi POM 5 untuk sain manajemen oleh Taylor Rp.48.597.000,-pada modul <em>linear programming </em>dan<em> transportation</em>. Walaupun hasil optimal sama tetapi jalur distribusi berbeda. Berdasarkan perhitungan langsung dibandingkan optimisasi secara manual maupun dengan <em>output</em> program POM-5. terjadi penurunan biaya transportasi sebesar Rp.2.795.000,- atau 5,44% dan perusahaan memiliki alternatif jadwal pengiriman yang diinginkan.</p>
Peluang Bisnis Perdagangan Negara Indonesia
Authors: Hartanti Maria Febri Piji , Zafrullah Ahmad 
Published: April 2021

Pertanian merupakan sebuah lapangan bisnis di Indonesia yang tidak akan pernah habis, dengan mempertimbangkan bahwa Indonesia memang memiliki kebudayaan sebagai negara pertanian dikarenakan tanahnya yang subur dan iklim yang mendukung untuk kegiatan pertanian.
Clinico-mycological Study of Dermatophytosis and Their Antifungal Susceptibility, A Hospital Based Study
Authors: Pradhan Manish Bhakta , Paudel Vikash 
Published: April 2021

Background: Dermatophytosis refers to superficial fungal infections of keratinized tissues caused by keratinophilic dermatophytes. It is the most common of the superficial fungal infections. Nowadays, these fungal infections are at a rise and run a prolonged course despite of treatment due to resistance to conventional antifungal agents. There is a felt need to conduct an epidemiological studies to know the change in the pattern and causes of widespread resistance.
Objectives: This study was aimed at identifying clinico-mycological patterns of dermatophytic infections in patients attending the dermatology outpatient department of a tertiary care hospital in Birgunj and the adjoining areas.
Methods: The study included cases of clinically diagnosed dermatophytosis from the outpatient department of Dermatology of National Medical College, Birgunj. Clinical and epidemiological data were collected as per proforma and skin scraping, hair plucking, and nail clipping were done and materials were examined microscopically by KOH mount then cultured on Sabouraud dextrose agar and antifungal susceptibility were done by disk diffusion test.
Results: here were 349 patients recruited in the study, with a male: female ratio of 1.6:1. The most commonly affected age group was 20–29 years (27.3%). Tinea corporis was the most common type observed (38.1%). Potassium hydroxide positivity was seen in 228 samples (65.3%) and culture positivity was found in 202 samples (57.9%). The most common species identified was Trichophyton rubrum (55%). The most sensitive drug was itraconazole, and more number of resistances was noted with fluconazole.
Conclusion: Dermatophytic infection is ecumenical in distribution with increased frequency in tropical and subtropical countries with variable epidemiology. Inadequate and irregular use of antifungal drugs has led to the emergence of resistant strains, which cause poor treatment outcomes. Thus, it is essential to test for antifungal sensitivity to check for resistance to antifungals.
Àngel Guimerà – czy tylko dobro narodowe Katalończyków?
Authors: Sawicka Anna 
Published: April 2021

Tematem artykułu jest sytuacja literatury tworzonej w Hiszpanii w języku mniejszościowym, katalońskim, i ocena szans, jakie literatura w tym języku miała na pokonanie stereotypu literatury peryferyjnej, a także recepcja tej literatury przedstawiona z perspektywy synchronicznej, współczesnej Àngelowi Guimerze, w Katalonii, w Hiszpanii i za granicą, a następnie w perspektywie diachronicznej – przełomu XX i XXI wieku. Pretekstem do poruszenia tego tematu stało się wielokrotne podejmowanie przez rodaków katalońskiego dramaturga Àngela Guimery prób (ostatecznie nieudanych) zarekomendowania go do Literackiej Nagrody Nobla.
Removal of cranial springs after spring-mediated cranioplasty
Authors: Kalmar Christopher L. , Swanson Jordan W. , Shakir Sameer , Tucker Alexander M. , Kennedy Benjamin C. , Storm Phillip B. , Heuer Gregory G. , Bartlett Scott P. , Taylor Jesse A. , Lang Shih-Shan 
Published: April 2021

Cranial spring hardware is generally removed 3 months after placement for spring-mediated cranioplasty. Spring removal is performed as an outpatient procedure under general anesthesia in approximately 15 minutes through the incision locations of the index procedure. Herein, the authors provide a multimedia demonstration of cranial spring hardware removal after spring-mediated cranioplasty for sagittal craniosynostosis.
The video can be found here: https://vimeo.com/511179695
Sagittal synostosis scaphocephaly cranial reconstruction with spiral cut cranioplasty
Authors: Wang Catherine Y. , Bonaroti Alisha R. , Miller Brandon A. , Liau James 
Published: April 2021

Sagittal craniosynostosis, the most common form of craniosynostosis, affects 1 per 1000 live births. The main surgical treatments include endoscopic suturectomy and open cranial vault remodeling. This video describes an open reconstruction method, including strip resection of the sagittal suture, biparietal craniotomies with spiral cut cranioplasty, and barrel staves of the posterior occiput. Ideally used between 4 and 15 months of age, this approach takes advantage of the flexibility of the cranial bones to expand, allowing for immediate and long-term increases of the parietal width and correction of cosmetic deformity, without necessitating the use of cranial molding devices postoperatively.
The video can be found here: https://vimeo.com/516699203
Open craniofacial reconstruction for coronal craniosynostosis
Authors: Bader Edward R. , Ammar Adam , Fortunel Adisson N. , De la Garza Ramos Rafael , Tepper Oren , Kobets Andrew J. 
Published: April 2021

Here the authors demonstrate open craniofacial reconstruction for the correction of craniosynostosis, using techniques refined by Dr. James T. Goodrich at Montefiore Medical Center. They present the operative management of a case of unilateral coronal synostosis in a 12-month-old child, who presented with right forehead prominence and calvarial asymmetry. The patient had an excellent correction of her head shape with an uneventful postoperative course. This video highlights the authors’ multidisciplinary approach to complete cranial vault remodeling, utilizing a Marchac bandeau construct and split calvarial graft mosaic technique.
The video can be found here: https://vimeo.com/519489422.
Minimally invasive strip craniectomy for metopic craniosynostosis using a lighted retractor
Authors: Hersh David S. , Lambert William A. , Bookland Markus J. , Martin Jonathan E. 
Published: April 2021

Surgical options for metopic craniosynostosis include the traditional open approach or a minimally invasive approach that typically involves an endoscopy-assisted strip craniectomy. The minimally invasive approach has been associated with less blood loss and operative time, a lower transfusion rate, and a shorter length of stay. Additionally, it is more cost-effective than open reconstruction, despite the need for a postoperative cranial orthosis and multiple follow-up visits. The authors describe a variation of the minimally invasive approach using a lighted retractor to perform a strip craniectomy of the metopic suture in a 2-month-old patient with metopic craniosynostosis.
The video can be found here: https://vimeo.com/511237503.
Endoscope-assisted right coronal suturectomy
Authors: McDowell Michael M. , Kellogg Robert , Goldstein Jesse A. , Abel Taylor J. 
Published: April 2021

Endoscopic suturectomy combined with supplementary techniques such as spring-assisted expansion and cranial molding helmets for the correction of craniosynostosis is growing in popularity due to the reduced scar burdened, decreased morbidity, and reduced overall cost. The authors present their technique for the correction of isolated coronal craniosynostosis. The use of dedicated endoscopic tools and lit endoscopes permits enhanced visualization and technical ability, particularly at the distal portions of the suturectomy, and may reduce operative time and cerebrospinal fluid leak risk.
The video can be found here: https://vimeo.com/515401366.
Endoscopic surgical treatment of bilateral coronal craniosynostosis
Authors: Jeelani Yasser , Proctor Mark R. 
Published: April 2021

Endoscopic surgery for single-suture synostosis has been widely adopted since its introduction over 2 decades ago. Its role in syndromic synostosis is emerging, both as a primary treatment and as the first stage in a multimodal treatment paradigm aimed at preventing the vexing turribrachycephaly seen in these children. In this video, the authors review the technique for endoscopic treatment of bilateral coronal craniosynostosis and discuss both the benefits and some of the concerns to look out for over time. They also review the long-term outcomes in a consecutive series of patients treated in this fashion.
The video can be found here: https://vimeo.com/516351348.
Endoscopic-assisted repair for sagittal synostosis
Authors: Smyth Matthew D. , Patel Kamlesh B. 
Published: April 2021

The craniofacial team at St. Louis Children's Hospital has been performing endoscopy-assisted synostosis surgery since 2006. Most infants with single-suture synostosis younger than 6 months of age are candidates. The sphinx position is used, with two incisions: one posterior to the bregma and one anterior to the lambda. The endoscope is incorporated primarily for epidural dissection and bone edge cauterization. Blood products are available but rarely needed with single suturectomies. Patients are managed on the floor after surgery and discharged to home on postoperative day 1, with helmet therapy coordinated and initiated immediately after surgery and continued until about 12 months of age.
The video can be found here: https://vimeo.com/513939623
Non-invasive assessment of tissue oxygenation parameters in diabetic patients foot sole using near infrared spectroscopy
Authors: Brindha M. , Seshadri N.P. Guhan , Periyasamy R. 
Published: April 2021

Background and Objective: Diabetic problems are more common in the lower extremity and linked with high mortality rate which affects public health system. The present study focused on monitoring the changes in tissue oxygenation concentrations using Near infrared spectroscopy system along with temperature and hardness of the foot tissues. Methods: Control subjects (without diabetes) and diabetic patients without neuropathy were selected for this study and three standard foot risk areas were considered. Standard induced ischemic stimulus was given to assess the response of the designed system and to analyze the changes in oxyhemoglobin and deoxyhemoglobin levels during venous occlusion. Results: Results showed significant differences in the tissue oxygenation index value in all three standard areas where oxygenation value at the foot areas were significantly low ( p < 0.05) in diabetic group as compared to control group. Also, significant difference were found in tissue hardness value when comparing between groups, where the diabetic group had significantly high ( p < 0.05) tissue hardness at area 5 and area 8 as compared to control groups. Conclusion: Therefore, the present study concludes that high tissue hardness had significant effect on tissue oxygenation index that affects vascular circulation and this condition could be assessable using NIRS technique in order to find risky areas at the foot sole.
Histological Analysis of Tibialis Anterior Muscle of DMDmdx4Cv Mice from 1 to 24 Months
Authors: Ben Larbi Sabrina , Saclier Marielle , Fessard Aurélie , Juban Gaëtan , Chazaud Bénédicte 
Published: April 2021

Background: The mdx-C57/B6 mouse model does not show the clinical signs of Duchenne muscular dystrophy (DMD), although muscles exhibit hallmarks of permanent regeneration and alterations in muscle function. The DMD mdx4Cv strain exhibits very few revertant dystrophin positive myofibers, making that model suitable for studies on gene and cell therapies. Objective: The study appraises the histological evolution of the Tibialis Anterior muscle of WT and DMD mdx4Cv mutant from 1 to 24 months. Methods: Histological analysis included a series of immunostainings of muscle sections for assessing tissue features (fibrosis, lipid deposition, necrosis) and cellular characteristics (size of myofibers, number and distribution of myonuclei, number of satellite cells, vessels, macrophages). Results: None of the investigated cell types (satellite cells, endothelial cells, macrophages) showed variations in their density within the tissue in both WT and DMD mdx4Cv muscle. However, analyzing their number per myofiber showed that in DMD mdx4Cv, myofiber capillarization was increased from 1 to 6 months as compared with WT muscle, then dropped from 12 months. Macrophage number did not vary in WT muscle and peaked at 6 months in DMD mdx4Cv muscle. The number of satellite cells per myofiber did not vary in WT muscle while it remained high in DMD mdx4Cv muscle, starting to decrease from 12 months and being significantly lower at 24 months of age. Myofiber size was not different in DMD mdx4Cv from WT except at 24 months, when it strongly decreased in DMD mdx4Cv muscle. Necrosis and lipid deposition were rare in DMD mdx4Cv muscle. Fibrosis did not increase with age in DMD mdx4Cv muscle and was higher than in WT at 6 and 12 months of age. Conclusions: As a whole, the results show a strong decrease of the myofiber size at 24 months, and an increased capillarization until 6 months of age in DMD mdx4Cv as compared with the WT. Thus, DMD mdx4Cv mice poorly recapitulates histological DMD features, and its use should take into account the age of the animals according to the purpose of the investigation.
Encouraging physical activities at home for people with multiple sclerosis with mHealth tools: A literature review
Authors: Chassan Clémence , Jost Céline , Sévène Marc , Cras Olivier , De Broucker Thomas , Archambault Dominique 
Published: April 2021

BACKGROUND: Multiple sclerosis (MS) is a chronic degenerative neurological disease with visual, sensitive, motor, or cognitive symptoms. Physical activities are recommended for people with MS (pwMS) who are at home instead of in a rehabilitation program, to help them to maintain their autonomy. Since a lack of motivation appears to be the principal barrier for pwMS to practice exercises, it is necessary to evaluate whether mobile health (mHealth) tools can offer a solution to stimulate their motivation. OBJECTIVE: This literature review analyzes papers to investigate to how a mobile application can motivate pwMS to practice physical activities and manage their fatigue. METHODS: We performed an automatic query from digital libraries and analyzed the studies. RESULTS: We selected seven articles that responded to our criteria. These studies tested mobile applications that used different strategies to motivate pwMS to practice physical exercises at home and manage their fatigue. A lack of motivation was the main obstacle, but depending on the type of exercises chosen, some application settings seemed to resolve this issue. CONCLUSIONS: Studies in this area are limited, although this literature review highlights the need for mHealth tools in which pwMS and their therapists contribute to their use and conception.
Comparing ten WCAG tools for accessibility evaluation of websites
Authors: Kumar Shashank , Shree DV Jeevitha , Biswas Pradipta 
Published: April 2021

BACKGROUND: Web accessibility is one of the most important aspects of building a website. It is important for web developers to ensure that their website is accessible according to WCAG standards for people with different range of abilities. There is plethora of tools for ensuring conformance to WCAG standards but not many studies compared performance of automatic WCAG tools. OBJECTIVE: This paper compares a set of ten WCAG tools and their results in terms of ease of comprehension and interpretation by web developers. We proposed a Common User Profile format to help personalize contents of website making it accessible to people with different range of abilities. METHODS: We selected ten WCAG tools from World Wide Web Consortium (W3C) to evaluate landing pages of two popular websites. For each webpage, we identified accessibility issues and recommended alternate suggestions to help developers improve accessibility. Further, we highlighted accessibility issues that cannot be captured only through conformance to WCAG tools; and proposed additional methods to evaluate accessibility through an Inclusive User Model. We then demonstrated how simulation of user interaction can capture usability and accessibility issues that are not detected through only syntactic analysis of websites’ content. Finally, we proposed a Common User Profile format that can be used to compare and contrast accessibility systems and services, and to simulate and personalize interaction for users with different range of abilities. RESULTS AND CONCLUSIONS: After careful evaluation of two websites using the ten tools, we noted that, both websites lacked color contrast between background and foreground; lack of sign language alternatives; opening of pop-ups without proper warnings and so on. Further, results from comparative analysis of selected web accessibility tools noted that, there is no single tool that can be found ideal in all aspects. However, from our study, Utilitia Validator by Utilitia SP. z O.O was considered the most feasible tool. By rectifying and incorporating issues and alternate suggestions by simulation study and Common User Profile format respectively, developers can improve both websites making it accessible to maximum audience.
A simple and fast ASD-POCS algorithm for image reconstruction
Authors: Qiao Zhiwei 
Published: April 2021

PURPOSE: The adaptive steepest descent projection onto convex set (ASD-POCS) algorithm is a promising algorithm for constrained total variation (TV) type norm minimization models in computed tomography (CT) image reconstruction using sparse and/or noisy data. However, in ASD-POCS algorithm, the existing gradient expression of the TV-type norm appears too complicated in the implementation code and reduces image reconstruction speed. To address this issue, this work aims to develop and test a simple and fast ASD-POCS algorithm. METHODS: Since the original algorithm is not derived thoroughly, we first obtain a simple matrix-form expression by thorough derivation via matrix representations. Next, we derive the simple matrix expressions of the gradients of TV, adaptive weighted TV (awTV), total p-variation (TpV), high order TV (HOTV) norms by term combinations and matrix representations. The deep analysis is then performed to identify the hidden relations of these terms. RESULTS: The TV reconstruction experiments by use of sparse-view projections via the Shepp-Logan, FORBILD and a real CT image phantoms show that the simplified ASD-POCS (S-ASD-POCS) using the simple matrix-form expression of TV gradient achieve the same reconstruction accuracy relative to ASD-POCS, whereas it enables to speed up the whole ASD process 1.8–2.7 time fast. CONCLUSIONS: The derived simple matrix expressions of the gradients of these TV-type norms may simplify the implementation of the ASD-POCS algorithm and speed up the ASD process. Additionally, a general gradient expression suitable to all the sparse transform-based optimization models is demonstrated so that the ASD-POCS algorithm may be tailored to extended image reconstruction fields with accelerated computational speed.