bluuebunny/crossref_metadata_2025_split huggingface dataset:
Theatre efficiency in COVID-19 pandemic conditions: The collaborative experience of four level 1 major trauma centres in the UK
Authors: Jeyaseelan Lucky , Sedgwick Philip , El-Daly Ibraheim , Tahmassebi Ramon , Pearse Michael , Bhattacharya Rajarshi , Trompeter Alex J. , Bates Peter ,   On behalf of London Major Trauma Collaborative
Published: October 2021

Aims As the world continues to fight successive waves of COVID-19 variants, we have seen worldwide infections surpass 100 million. London, UK, has been severely affected throughout the pandemic, and the resulting impact on the NHS has been profound. The aim of this study is to evaluate the impact of COVID-19 on theatre productivity across London’s four major trauma centres (MTCs), and to assess how the changes to normal protocols and working patterns impacted trauma theatre efficiency. Methods This was a collaborative study across London’s MTCs. A two-month period was selected from 5 March to 5 May 2020. The same two-month period in 2019 was used to provide baseline data for comparison. Demographic information was collected, as well as surgical speciality, procedure, time to surgery, type of anaesthesia, and various time points throughout the patient journey to theatre. Results In total, 1,243 theatre visits were analyzed as part of the study. Of these, 834 patients presented in 2019 and 409 in 2020. Fewer open reduction and internal fixations were performed in 2020 (33.5% vs 38.2%), and there was an increase in the number of orthoplastic cases in 2020 (8.3% vs 2.2%), both statistically significant results (p < 0.000). There was a statistically significant increase in median time from 2019 to 2020, between sending for a patient and their arrival to the anaesthetic room (29 vs 35 minutes; p = 0.000). Median time between arrival in the anaesthetic room and commencement of anaesthetic increased (7 to 9 minutes; p = 0.104). Conclusion Changes in working practices necessitated by COVID-19 led to modest delays to all aspects of theatre use, and consequently theatre efficiency. However, the reality is that the major concerns of impact of service did not occur to the levels that were expected. Cite this article: Bone Jt Open 2021;2(10):886–892.
Evaluating Surveillance for and Estimating Administration of Rabies Postexposure Prophylaxis in the United States, 2012–2018
Authors: Whitehouse Erin R. , Person Marissa K. , Brown Catherine M. , Slavinski Sally , Rao Agam K. , Blanton Jesse D. 
Published: October 2021

BackgroundAn evaluation of postexposure prophylaxis (PEP) surveillance has not been conducted in over 10 years in the United States. An accurate assessment would be important to understand current rabies trends and inform public health preparedness and response to human rabies.Methodology/Principle findingsTo understand PEP surveillance, we sent a survey to public health leads for rabies in 50 U.S. states, Puerto Rico, Washington DC, Philadelphia, and New York City. Of leads from 54 jurisdictions, 39 (72%) responded to the survey; 12 reported having PEP-specific surveillance, five had animal bite surveillance that included data about PEP, four had animal bite surveillance without data about PEP, and 18 (46%) had neither. Although 12 jurisdictions provided data about PEP use, poor data quality and lack of national representativeness prevented use of this data to derive a national-level PEP estimate.We used national-level and state specific data from the Healthcare Cost & Utilization Project (HCUP) to estimate the number of people who received PEP based on emergency department (ED) visits. The estimated annual average of initial ED visits for PEP administration during 2012–2017 in the United States was 46,814 (SE: 1,697), costing upwards of 165 million USD. State-level ED data for initial visits for administration of PEP for rabies exposure using HCUP data was compared to state-level surveillance data from Maryland, Vermont, and Georgia between 2012–2017. In all states, state-level surveillance data was consistently lower than estimates of initial ED visits, suggesting even states with robust PEP surveillance may not adequately capture individuals who receive PEP.ConclusionsOur findings suggest that making PEP a nationally reportable condition may not be feasible. Other methods of tracking administration of PEP such as syndromic surveillance or identification of sentinel states should be considered to obtain an accurate assessment.
Antioxidant Activity and Cytotoxic Potential of Parijoto (Medinilla speciosa (Reinw ex BL)) Fruit Fractions on HeLa Cell Line
Authors: Winanta Aji , Hanik Linta Sabila , Febriansah Rifki 
Published: October 2021

Parijoto (Medinilla speciosa (Reinw ex BL)) is one of the Indonesian indigenous plants widely used as traditional medicine. A previous study showed that ethanol and methanol extracts of Parijoto fruit could inhibit T47D breast cancer cells. This study explores the antioxidant and cytotoxic activities of Parijoto fruit extract and fractions on HeLa cell line. The fruits were extracted using ethanol 70% and fractionated by hexane and ethyl acetate. Furthermore, the fraction was analyzed for secondary phytochemical metabolite content using thin-layer chromatography and staining reagents. The antioxidant and cytotoxic activities were determined using the DPPH scavenging assay and the MTT assay, respectively. The ethanol extract and fraction contained flavonoid and tannin compounds. Ethanol extract, ethanol fraction, and ethyl acetate fraction of Parijoto fruit had an antioxidant activity with IC50 values of 77.3, 88.64, and 46.61 μg/mL, respectively. Ethyl acetate fraction showed the highest activity on HeLa cells with an IC50 value of 45.57 μg/mL compared to ethanol extract, ethanol fraction and n-hexane fraction with an IC50 value of 233.43, 700.75, and 534.30 μg/mL, respectively. Based on these results, the ethyl acetate fraction of Parijoto fruit had the potency to be explored further to elucidate their cytotoxicity mechanism in HeLa cells.Keywords: antioxidant activity, cytotoxicity, Medinilla speciosa, Parijoto fruit fractions.
Cevian properties in ideal lattices of Abelian ℓ-groups
Authors: Ploščica Miroslav 
Published: October 2021

Abstract
We consider the problem of describing the lattices of compact

ℓ

{\ell}

-ideals of Abelian lattice-ordered groups. (Equivalently, describing the spectral spaces of Abelian lattice-ordered groups.) It is known that these lattices have
countably based differences and admit a Cevian operation. Our first result
says that these two properties are not sufficient: there are lattices having both
countably based differences and Cevian operations, which are not representable
by compact

ℓ

{\ell}

-ideals of Abelian lattice-ordered groups. As our second result,
we prove that every completely normal distributive lattice of cardinality at
most

ℵ
1

{\aleph_{1}}

admits a Cevian operation. This complements the recent result of F.
Wehrung, who constructed a completely normal distributive lattice having countably based differences,
of cardinality

ℵ
2

{\aleph_{2}}

, without a Cevian operation.
Analysis of Vaccination of Children and Its Timing Against Infections from the National Immunization Schedule in the Volga and Far Eastern Federal Districts of Russian Federation: Cross-Sectional Study
Authors: Mukozheva Radima A. , Kulichenko Tatyana V. , Vilchanskaya Tatyana V. , Romanova Olga V. , Lazareva Mariya A. , Lashkova Juliya S. , Artemova Inga V. 
Published: October 2021

Background. Delayed vaccination increases the period of vulnerability of children to vaccine preventable diseases. It is associated with higher risk of infectious morbidity and outbreaks (including previously controlled diseases).Objective. Our aim was to study the vaccination of children and its timing according to the National Immunization Schedule (NIS) in Russian Federation regions.Methods. We have performed retrospective cross sectional study. Data from 2838 maps of preventive vaccinations (form No 063/y) in children of 2015-2017 years of birth from 18 subjects of Volga and Far Eastern federal districts, as well as data from the state federal statistical monitoring forms No 6 “Information on children and adults populations vaccinated against infectious diseases" in 2016-2019 in the same subjects of Russian Federation was analyzed.Results. The proportion of children vaccinated according to the NIS varies from 8% to 87.1% (depending on the vaccine type). 51.5-94.5% of children are vaccinated timely to decreed dates according to the age criteria used in Form No 6. Whereas, more than 95% of children were considered vaccinated against infections from the NIS list (except pneumococcal infection) according to official statistics. Significant regional differences in vaccination of children and its timing were revealed.Conclusion. Significant numbers of children remains unvaccinated or are or untimely vaccinated against infections from the NIS list. At the same time, there is considerable difference between the data about vaccination and its timing received from the analysis of primary medical documentation and from the state federal statistical monitoring forms.
Knowledge of Future Doctors (Senior Students, Interns, Residents) on Breastfeeding: Cross-Sectional Study
Authors: Yakovlev Yakov Y. , Manerov Farok K. , Furtsev Vladimir I. , Shcherbak Vladimir A. , Shcherbak Natalya M. , Lobanov Uri F. , Ledyaykina Lyudmila V. , Garina Svetlana V. , Surovikina Ekaterina A. , Yolkina Tatyana N. , Alimova Irina L. , Pleskachevskaya Tatiana A. , Popova Elena V. , Pogorelova Larisa V. , Revnova Maria O. , Gaiduk Irina M. , Burlutskaya Alla V. , Statova Anastasia V. , Jumagaziev Anvar A. , Kashirskaya Elena I. , Tsarkova Sofya A. , Trunova Yulia A. , Koltsova Nadezhda S. , Pechkurov Dmitry V. , Lazareva Elena P. , Lukushkina Elena F. , Neufeld Irina V. , Rogozhina Irina E. , Makarova Valeria I. , Petrov Ivan M. , Sakharov Sergey P. , Shevchenko Elena V. , Malakhova Zhanna L. , Pashov Alexander I. , Munkhalova Yana A. , Egorova Vera B. , Kaladze Nikolay N. , Belykh Natalya A. 
Published: October 2021

Background. The ratio of breasted children for more than six months increased from 33 to 40% in the period from 1991 to 2019 according to the Russian Federal State Statistics Service. This number has not changed in recent 12 years and remained on the level of 39-41%. Relatively low adherence to breastfeeding may be the consequence of the lack of training of future doctors in these issues.Objective. The aim of the study was to analyse the knowledge (and its dynamics over the past decade) of medical students, interns and residents on breastfeeding support and promotion in Russian Federation.Methods. We have conducted the survey among senior students, interns, and residents in 2009-2011 and 2018-2019. 8 medical universities participated in the study in 2009-2011, and 24 medical universities and one continuing education institute — in 2018-2019. Knowledge on breastfeeding support issues was estimated according to the results of future doctors’ responses to the proposed questionnaires.Results. Sample of 2009-2011 has included 1088 students, interns, and residents, sample of 2018-2019 — 3694. There is still high level of mistakes in the breastfeedng issues due to the decline in knowledge of the WHO breastfeeding recommendations. The level of understanding of practical aspects has not changed significantly over the 10 years, and there is still a gap between theoretical knowledge and practice.Conclusion. The necessity to improve quality of future doctors training in breastfeeding issues is shown.
Design of a solar energy harvesting system for supplying energy to an autonomous wireless sensor node
Authors: Salazar Cardona Mónica María 
Published: October 2021

Introduction: This paper is the product of the research “Generation of a modular electronic platform for the conformation of a WSN” developed in the EAFIT University in 2019.
Problem: Wireless Sensor Networks (WSNs) are used as a technology of information and communication (TIC) to automate processes. Its implementation is considered non-efficient, because of their high cost concerning to the batteries replacement that the nodes conforming the WSN, require.
Objective: The objective of the research is to develop more efficient solar energy harvesting systems that can guarantee an average performance of the wireless sensor node at a low cost.
Methodology: Here we present the design and the implementation of a solar energy harvesting system that integrates a buck converter, a maximum power point tracking (MPPT) control, and a wireless sensor node. Besides, we do measures of voltage at the output of the buck converter and estimation of energy autonomy in the wireless sensor node.
Results: Autonomous operation with the solar energy harvesting system was rich for the node sending packages each 20 min.
Conclusion: This article presented a solar energy harvesting system with the implementation of an MPPT control.
Originality: Through this research, parameters of the MPPT control are formulated for the first time for the solar energy harvesting system design, based on the duty cycle limits.
Limitations: The availability of the devices used in the implementation of the proposed design.
Impact of structure on team performance
Authors: Acevedo González Catherine , Rodriguez Lopez Maria Fernanda , Bohorquez Arevalo Luz Esperanza 
Published: October 2021

Introduction:
This article is product of research on business self-organization developed at the Universidad Distrital Francisco Jose de Caldas on 2019-2020 starting from that collective intelligence (CI) has been viewed as an approach that enables from the use of the interactions among the agents and between these and the environment to increase the intelligence of the system; understood as the ability to take full advantage of distributed resources and to adapt nimbly to the changing conditions of the environment

Methodology: in the first part, the conditions that may facilitate CI are explored through a review of the literature. In the second part an experiment is designed in a micro-world environment in which incorporate some of the conditions identified to facilitate the CI in the structure of a team and its performance is compared with a team that has a hierarchical structure.

Results: the teams that have a structure with facilitates CI, present on average greater performance, coordination effectiveness and adaptability, as well as better interaction dynamics among the members. These teams present higher levels of interaction, information flows and activity among the participants, reflected in the number of interventions and in the use of the resources offered in the game.

Conclusions: the increase in complexity that the application of IC inducers gives the team could be a predictor of better performances in environments of increasing complexity; in contrast to teams that have structures that reduce their complexity as the hierarchical structure.

Originality: This article provides evidence regarding the incidence of roles in the performance of the company.

Limitations: one of the main constraints is the virtual interaction between the participants and between them with the research team. Face-to-face interaction would allow more intensive use of affiliate links between participants.

Keywords: collective intelligence, micro-world, hierarchical structure, organizational structure
PROPIONYLCARNITINE AND FREE CARNITINE ARE NEW BIOMARKERS IN THE FOLLOW-UP PERIOD OF MUCOPOLYSACCARIDOSIS TO SCREEN OXIDATIVE STRESS
Authors: İNCİ Aslı , OLGAC Asburce , GENÇ DERİN Betül , BİBEROĞLU Gürsel , OKUR İlyas , EZGÜ Fatih Süheyl , TÜMER Leyla 
Published: October 2021

Objective
There is no applicable and easy procedure to screen
oxidative stress in mucopolysaccaridosis (MPS)
patients. The aim herein was to show the antioxidative
properties of free carnitine (FC) and propionylcarnitine
(PC) with respect to oxidative markers in MPS and
use a simple and easy method in patient follow-up.
Material and Methods
FC and PC were studied as an antioxidative
marker using tandem mass spectroscopy and
malondialdehyde (MDA) was studied as an oxidative
marker in 27 MPS patients and 24 healthy volunteers.
Results
While the PC and FC levels were significantly
decreased, the MDA levels were higher in the
MPS patients than in the healthy volunteers.When
compared between the enzyme-treated MPS patients
and untreated MPS patients, there were no significant
differences between the groups. MDA was found to
inversely correlated with PC (r =–0.402, P=0.003).It
was noteworthy that PC had a significant correlation
with MDA.
Conclusion
The findings revealed that the affected patients had
higher MDA levels and lower PC and FC levels,
indicating an imbalance through the oxidative side. An
applicable method of FC and PC measurement could
be used to screen patients, considering them as new
antioxidative markers in the patient follow-up period
for the response of enzyme replacement therapy and/
or antioxidant drugs.
The Legal Nature of Payment for Unilateral Refusal to Fulfill an Obligation
Authors: Chegovadze L. A. , Deryugina T. V. 
Published: October 2021

The paper analyzes the possibility of unilateral refusal to fulfill an obligation through the payment of a monetary sum. The multidimensionality of the development of a legal relationship related to the fulfillment of an obligation is investigated in the context of the opportunity to use various legal remedies at each stage of a legal relationship. The paper shows the transformation of the legal statuses of the creditor and the debtor in the process of exercising rights and fulfilling obligations. It is substantiated that, depending on the stage of development of the legal relationship in mutual obligations, the creditor and the debtor alternately change their capabilities to demand performance and fulfill obligations. Failure to fulfill an obligation at any stage leads to the possibility of making claims for the protection of the right. It is indicated that the agreement in the contract of the obligation of the debtor to pay the creditor a certain amount of money in the event of refusal to perform the obligation does not change the legal nature of the obligation and does not make it monetary. It is proved that the refusal to fulfill the obligation becomes legally possible only after the fulfillment of the obligation to pay the counterparty a sum of money. The author establishes the legal nature of such a replacement in comparison with the novation of debt into a debt obligation. It is proved that a different interpretation of the law violates the balance of interests between the debtor and the creditor.
Análise de propriedades das séries temporais dos ativos que compõem o índice IBOVESPA
Authors: Berci César Daltoé , Bottura Ceslo Pascoli 
Published: October 2021

Diversas características das séries temporais financeiras são de interesse tanto do ponto de vista acadêmico, onde pretende-se analisar a dinâmica dos dados e suas propriedades numéricas, bem como de investidores, que por sua vez utilizam-se desse conhecimento na intensão de obter lucro em suas transações financeiras. Através da aplicação de diversas ferramentas de análise, fazendo uso de uma capacidade de computação massiva, foram avaliados os ativos que compõem o índice IBOVESPA, quanto suas propriedades numéricas e estatísticas. Dada a relevância e abrangência das séries temporais analisadas, os resultados obtidos a partir desta análise podem servir como base para a caracterização das séries temporais financeiras. http://dx.doi.org/10.18226/23185279.v9iss2p05
Documentando o bairro de Bodocongó em Campina Grande [PB]
Authors: Melo Alcília Afonso de Albuquerque , Pereira Ivanilson Santos , Jales Lucas de Souza 
Published: October 2021

O artigo possui como objeto de estudo a análise da paisagem natural e construída do bairro de Bodocongó em Campina Grande, agreste paraibano do nordeste brasileiro, que teve sua origem e consolidação vinculadas ao processo de modernização e industrialização regional, ocorridos nas décadas de 50 a 70 do século XX. O objetivo é observar o diálogo entre arquitetura, paisagem e patrimônio industrial, refletindo sobre as mudanças sofridas nas paisagens naturais e construídas deste bairro ao longo de sete décadas, baseadas em documentos originais e gerados pela pesquisa, analisando-se o que foi mantido de sua paisagem natural, e de sua história arquitetônica vinculada ao segmento industrial. Para comprovar as hipóteses e procurar caminhos ou respostas para os questionamentos, a pesquisa vem se apoiando em metodologia da história da arquitetura e do urbanismo desenvolvida por Serra (2006) que propõe o estudo do objeto compreendido como um processo, que dialoga com um sistema que o circunda, composto por aspectos geográficos, históricos, sociais, culturais, econômicos, políticos. Considera-se nesta pesquisa de fundamental importância a interdisciplinaridade e a multidisciplinaridade destes saberes.
Gestão democrática e formação de professores
Authors: Casagrande Ana Lara 
Published: October 2021

Ao refletir sobre gestão democrática e formação de professores no Brasil, com ênfase no caminho traçado para a cidadania, no Estado patrimonial, na universidade pública e no papel dos formadores de professores diante dos mecanismos de participação, este texto objetiva problematizar a formação de professores como um eixo fundante da promoção dos valores que fomentam a atuação voltada para uma gestão democrática na escola, bem como o entendimento da sua importância. Para cumprir com tal objetivo, é feito um estudo exploratório, de abordagem qualitativa. Partimos do pressuposto de que, na Educação Superior, a discussão crítica sobre o papel do Estado e a participação popular estimulam a formação de professores comprometida com uma proposta de educação (e gestão) conduzida por um processo efetivamente democrático. Esse adjetivo empregado junto ao Estado brasileiro tem um caminho complexo e lento de firmamento de raízes em solo não tão fértil, o que faz com que seja necessário discutir tais idiossincrasias, temendo ventos fortes no sentido contrário, que abalem o pouco de sombra que se formou até aqui.
IDENTIFIKASI KARAKTERISTIK KORBAN KECELAKAAN LALU LINTAS DI SIDOARJO TAHUN 2016
Authors: Septianingtyas Daniar Mukti 
Published: October 2021

Traffic accident becomes a very serious case because it causes not only material loss but also physical and psychological harms to the subject and the people around him. Accidents that occurred resulted in not only injuries but also death. This study aims to identify characteristics of traffic accident victims in Sidoarjo in 2016. It was an observational study with cross sectional design and based on daily data of traffic accident with 735 samples. Data were processed by ordinal logistic regression statistic test. In this case, variables of the study included the severity of victim, age, gender, profession, time of occurrence, type of collision, and type of vehicle. The results of characteristic identification showed that most of the victims had minor injuries, were male, aged ≥ 34 years old, workers, and got into accidents in the afternoon. The conclusion was factors affecting the severity of traffic accident victims in Sidoarjo were head-on-collisions (hitting straight) and motorcycles as the vehicle type. Modelling obtained was 3,133 for the constant of head-on-collision (hitting straight), 1,464 for the constant of vehicle type (motorcycles), and Y value of 4,597. This study was not supported by complete predictor data, thus the data need to be added so that the accuracy of classification increases and the value gets significant.