bluuebunny/crossref_metadata_2025_split huggingface dataset:
Temporal trends in utilization and outcomes of transcatheter aortic valve replacement in different races: an analysis of the national inpatient sample
Authors: Ullah Waqas , Al-Khadra Yasser , Mir Tanveer , Darmoch Fahed , Pacha Homam M. , Sattar Yasar , Ijioma Nketchi , Mohamed Mohamed O. , Kwok Chun S. , Asfour Abedelrahim I. , Kapadia Samir , Rizik David , Zehr Kenton , Mamas Mamas A. , Alraies M. Chadi 
Published: March 2021

Aim
We sought to determine the racial and ethnical disparities in the delivery of TAVR and to evaluate the in-hospital outcomes and utilization of TAVR stratified by patient ethnicity.

Method
Using a national inpatient sample database between 2011 and 2015, we identified all adult patients who had TAVR. Races were identified and white race was set as control. Multiple logistic regression analysis was performed for the primary outcome of in-hospital mortality.

Results
Out of 58 174 patients who underwent TAVR, 50 809 (87.3%) were white, 2327 (4.0%) were black, 2311 (4.0%) were Hispanic, 640 (1.1%) Asian, 105 (0.2%) Native American and 1982 (3.4%) of other ethnicities. We found a statistically significant linear uptrend in the utilization of TAVR in patients of all races between the years 2011 and 2015. White, black, Hispanic and Native American patients had a downward linear trend for mortality during the studied years (P ≤ 0.005 for all). Black patients had lower in-hospital mortality [2.8 vs. 3.6%, odds ratio (OR) = 0.62; 95% confidence interval (CI) 0.44, 0.81 P < 0.001] compared with white patients, whereas Hispanic patients and Native Americans had higher in-hospital mortality compared with white patients (4.5% OR 1.26; 95% CI 1.01, 1.56 P = 0.041), (9.5% OR 4.44; 95% CI 2.25, 8.77 P < 0.001), respectively.

Conclusion
Overall, TAVR utilization is associated with lower mortality. There is a rising trend in utilization of TAVR in the black population with a significantly favorable mortality trend compared with the white population.
Oral aspirin or low dose of intravenous lysine acetylsalicylate in ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention
Authors: Ferlini Marco , Leonardi Sergio , Mandurino Mirizzi Alessandro , Montalto Claudio , Crimi Gabriele , Repetto Alessandra , Marinoni Barbara , Somaschini Alberto , Ferrario Maurizio , Klersy Catherine , Oltrona Visconti Luigi 
Published: March 2021

Aim
To compare the pharmacodynamic effect of an oral loading dose of ‘noncoated’ ASA 300 mg vs. an intravenous bolus injection of lysine acetylsalicylate 150 mg in patients with STEMI undergoing pPCI.

Methods
This was a prospective single-center, open label, pharmacodynamic study, including nonconsecutive patients presenting at our catheterization laboratory with STEMI undergoing pPCI and not receiving ASA within the previous 7 days. Pharmacodynamic analyses were performed at five time points: baseline, and 1, 2, 4 and 12 h after the loading dose, and measured as ASA reaction units (ARU) by the Verify Now System. An ARU more than 550 was considered as nonresponsiveness to study drugs. The primary end point was the different rate of patients with ARU more than 550 at 2 h after the loading dose of oral vs. intravenous ASA. Secondary end points included the comparison of ARU more than 550 at the other time points and the comparison of continuous ARU at each time point.

Results
The study was planned with a sample size of 68 patients, but it was prematurely stopped due to slow enrollment after the inclusion of 23 patients, 12 randomized to oral ASA and 11 to intravenous lysine acetylsalicylate. At 2 h the rate of patients with ARU more than 550 was numerically but not significantly higher in patients receiving oral ASA as compared with intravenous lysine acetylsalicylate (33 vs. 14.2%; Δ −0.19, 95% confidence interval −0.59–0.21, P = 0.58). The difference over time was NS (P = 0.98), though the prevalence of ARU more than 550 was higher at the other time points. Both routes of administration reduced ARU values over time, though with no overall significant difference between profiles (P overall = 0.48).

Conclusion
In patients with STEMI undergoing pPCI the rate of nonresponsiveness to ASA was not different comparing an oral ‘noncoated’ loading dose of ASA with an intravenous bolus injection of lysine acetylsalicylate. However, as patient enrollment was prematurely terminated, this study is underpowered to draw a definite conclusion.
Hubungan antara perempuan perokok pasif dan kejadian stroke di RSUD dr. Abdul Aziz Singkawang
Authors: Padillah Arif , An An An An , Zakiah Mistika 
Published: March 2021

Latar Belakang: Stroke atau penyakit serebrovaskuler mengacu kepada setiap gangguan neurologik mendadak akibat pembatasan atau terhentinya aliran darah melalui sistem suplai arteri otak. Salah satu faktor resiko stroke yaitu rokok. Rokok adalah salah satu produk tembakau yang dimaksudkan untuk dibakar dan diisap dan/ atau dihirup asapnya. Asap Rokok menimbulkan polusi terhadap perokok pasif dan lingkungan sekitarnya. Berbagai penelitian membuktikan perokok pasif mempunyai risiko yang lebih besar dari perokok aktif untuk terkena penyakit jantung koroner, stroke, emphysema, kanker paru, yang semuanya itu merupakan sebab utama kematian. Kebanyakan perokok pasif merupakan perempuan dan anak. Dengan demikian perokok pasif merupakan masalah perempuan dan anak karena dampak negatif dari asap rokok terhadap kesehatan mereka. Metode: Penelitian ini merupakan penelitian analitik observasional dengan desain penelitian cross sectional. Penelitian ini melibatkan 38 pasien wanita yang terpapar asap rokok dan dilakukan pencocokan dalam hal umur serta pekerjaan. Hasil: uji statistik menunjukkan terdapat hubungan antara perempuan perokok pasif dan kejadian stroke di RSUD Abdul Aziz Singkawang (p=0,036). Kesimpulan: Terdapat hubungan antara perempuan perokok pasif dan kejadian stroke di RSUD Abdul Aziz Singkawang.
Isolasi, Identifikasi dan Aktivitas Antibakteri Bakteri Endofit Daun Pegagan (Centella asiatica L.) terhadap Escherichia coli
Authors: Adityawarman Adityawarman , Mahyarudin Mahyarudin , Effiana Effiana 
Published: March 2021

Latar Belakang. Di Indonesia diare masih merupakan masalah kesehatan masyarakat. Tanaman pegagan telah digunakan untuk pengobatan diare. Bakteri endofit adalah bakteri yang hidup di dalam jaringan tanaman inang. Beberapa jenis bakteri endofit mampu menghasilkan senyawa aktif yang bersifat antibiotik. Metode. Penelitian ini merupakan penelitian deskriptif-eksploratif. Isolasi bakteri endofit dari daun pegagan (C.asiatica L.) menggunakan metode tanam langsung, potensi antibakteridiuji dengan metode difusi cakram. Identifikasi bakteri endofit dilakukan dengan pengamatan morfologi koloni, morfologi sel dan uji biokimia. Hasil. Sebanyak 4 dari 42 isolat memiliki potensi sebagai antibakteri terhadap pertumbuhan bakteri Escherichia coli. Isolat 16 memiliki kemampuan tertinggi yaitu dengan zona hambat 6,5 mm. isolat 16 memiliki kemiripan dangan genus Pseudomonas. Kesimpulan. Sebanyak 4 isolat bakteri endofit yang mempunyai potensi antibakteri terhadap Escherichia coli
Hubungan kadar CD4 terhadap kejadian infeksi oportunistik pada penderita HIV/AIDS di RSUD dr. Soedarso Pontianak tahun 2013
Authors: Natalia Diana , Susanti Wiwi E , Mukarromah Afifah 
Published: March 2021

Latar belakang: HIV menyerang sistem kekebalan tubuh manusia yaitu limfosit CD4, sehingga semakin berkembangnya penyakit di tubuh, maka jumlah limfosit CD4 juga semakin menurun yang dapat meningkatkan risiko terjadinya infeksi oportunistik. Tujuan penelitian ini untuk mengetahui hubungan kadar CD4 terhadap kejadian infeksi oportunistik. Metode: Desain penelitian ini menggunakan studi analitik dengan pendekatan cross sectional yang dilakukan di Klinik Melati RSUD dr. Soedarso kota Pontianak tahun 2013 dengan jumlah 85 sampel. Hasil: Hasil penelitian didapatkan rata-rata kadar CD4 adalah 165 sel/µldengan infeksi oportunistik yang tersering adalah tuberkulosis (27,9%), diikuti dengan diare (25,6%) dan kandidiasis orofarings (11,6%). Kesimpulan: Terdapat hubungan yang bermakna antara kadar CD4 terhadap kejadian infeksi oportunistik pada penderita HIV/AIDS di klinik melati RSUD dr. Soedarso kota Pontianak tahun 2013.
Metaphorical and Strategic Competence in the Spanish Language Teaching Classroom as a Foreign Language through Task-Based Learning Methodology
Authors: Enriquez Javier Julian 
Published: March 2021

This article focuses on highlighting the application of discourse analysis in the Spanish Language Teaching as a Foreign Language. Especially, it does emphasize the importance of the conceptual fluency acquisition, as a strategic competence in particular, and as a communicative competence in general for non-native speakers of other languages enrolled in Spanish courses as a foreign language. That is, it does draw attention to Metaphorical Competence (MC), which can be defined as the ability to acquire, create, and interpret metaphors in the target language. For this purpose, we have chosen a Golden Age poet, Gongora, considered by most literary critics as the most influential and important poet in Spanish-language poetry, whose works represent the most admirable literary masterpieces in the western classical literature and Baroque poetry. In the same way, we would like to bring to light his literary value, excellent, and didactic potential for teaching poetry in the second language classroom, underpinned by a Task-based Learning methodology.
PENGARUH PENGGUNAAN MEDIA AUDIO VISUAL TERHADAP HASIL BELAJAR MATEMATIKA SISWA SMP DI ERA PANDEMI COVID-19
Authors: Jusmiana Andi , Herianto Herianto , Awalia Rabiatul 
Published: March 2021

Penelitian ini merupakan penelitian eksperimen semu (quasi eksperiment) yang bertujuan untuk mengetahui pengaruh penggunaan media audio visual (Video) terhadap hasil belajar matematika siswa. Penelitian dilaksanakan di SMP Negeri 1 Libureng Kabupaten Bone dengan populasi sebanyak 282 siswa. Melalui teknik purposive sampling, didapatkan sampel penelitian sebanyak 53 siswa, terdiri dari 25 siswa kelas IX.A sebagai Kelas kontrol dan 28 siswa kelas IX.B sebagai kelas eksperimen. Penelitian ini berlangsung selama pandemi COVID-19 sehingga segala aktivitas pembelajaran dilakukan dengan sistem Daring menggunakan google classroom. Kelas kontrol diberikan perlakuan sebagaimana yang biasa dilakukan oleh guru mata pelajaran matematika yakni pembelajaran menggunakan media gambar. Sedangkan kelas eksperimen menggunakan media audio visual. Instrumen dalam penelitian ini yakni berupa tes hasil belajar yang terdiri dari pretest dan posttest. Hasil penilitian menunjukkan rata-rata hasil belajar matematika siswa setelah pemberian pretest pada kelas kontrol sebesar 59,60 dan pada kelas eksperimen sebesar 58,57. Sedangkan hasil posttest menunjukan rata-rata hasil belajar siswa pada kelas kontrol sebesar 65,60 dan pada kelas eksperimen sebesar 75,71. Berdasarkan uji normalitas, hasil pretest dan posttest siswa pada kelas kotrol maupun kelas eksperimen berdistribusi normal dan homogen. Uji-t menunjukkan nilai sig. (2-tailed) sebesar 0,024 < 0,05 sehingga H0 ditolak dan H1 diterima yang berarti terdapat perbedaan nilai rerata posttest antara kelas control dan kelas eksperimen. Didapatkan pula nilai thitung sebesar 2,329 dan ttabel (0,05/2;df) sebesar 2,007. Karena thitung=2,329 > ttabel=2,007 maka Ho ditolak dan h1 diterima yang berarti bahwa terdapat pengaruh penggunaan media audio visual(video) terhadap hasil belajar siswa.
A Note on Full and Complete Binary Planar Graphs
Authors: Casinillo Emily L , Casinillo Leomarich F 
Published: March 2021

Let G=(V(G), E(G)) be a connected graph where V(G) is a finite nonempty set called vertex-set of G, and E(G) is a set of unordered pairs {u, v} of distinct elements from V(G) called the edge-set of G. If is a connected acyclic graph or a connected graph with no cycles, then it is called a tree graph. A binary tree Tl with l levels is complete if all levels except possibly the last are completely full, and the last level has all its nodes to the left side. If we form a path on each level of a full and complete binary tree, then the graph is now called full and complete binary planar graph and it is denoted as Bn, where n is the level of the graph. This paper introduced a new planar graph which is derived from binary tree graphs. In addition, a combinatorial formula for counting its vertices, faces, and edges that depends on the level of the graph was developed.
Magic Realism as Rewriting Postcolonial Identity: A Study of Rushdie’s Midnight’s Children
Authors: Sharma Khum Prasad 
Published: March 2021

Magic realism as a literary narrative mode has been used by different critics and writers in their fictional works. The majority of the magic realist narrative is set in a postcolonial context and written from the perspective of the politically oppressed group. Magic realism, by giving the marginalized and the oppressed a voice, allows them to tell their own story, to reinterpret the established version of history written from the dominant perspective and to create their own version of history. This innovative narrative mode in its opposition of the notion of absolute history emphasizes the possibility of simultaneous existence of many truths at the same time. In this paper, the researcher, in efforts to unfold conditions culturally marginalized, explores the relevance of alternative sense of reality to reinterpret the official version of colonial history in Salman Rushdie’s Midnight’s Children from the perspective of magic realism. As a methodological approach to respond to the fiction text, magic realism endows reinterpretation and reconsideration of the official colonial history in reaffirmation of identity of the culturally marginalized people with diverse voices.
Prediksi Harga Rumah Menggunakan General Regression Neural Network
Authors: Rahayuningtyas Evi Febrion , Rahayu Feny Novia , Azhar Yufis 
Published: March 2021

Rumah merupakan salah satu kebutuhan manusia selain sandang dan pangan. Hirarki Kebutuhan Maslow menyebutkan bahwa rumah adalah salah satu Physiological Needs. Dewasa ini, kebutuhan akan rumah sering dijadikan sebagai sumber investasi bagi pengusaha properti yang tentunya menghasilkan investasi yang tidak dapat diremehkan. Keuntungan dalam jual beli rumah dijadikan alasan bagi seseorang dalam melakukan transaksi jual beli rumah itu sendiri. Sehingga munculah harga yang tidak terprediksi pada harga rumah yang ada. Penelitian ini menggunakan General Regression Neural Network sebagai pemodelannya. GRNN menggunakan dasar regresi non linear dimana strukturnya terdiri dari 4 layer, yaitu Input Layer, Pattern Layer, Summation Layer dan Output Layer. Variabel dependen yang digunakan berjumlah 6. Terdiri dari tanggal transaksi, jarak rumah dari stasiun MRT, jumlah toko atau minimarket yang dekat dengan rumah, umur rumah, dan letak geografis berupa longitude dan latitude. Variabel independen berupa harga rumah dalam satuan luas Ping yang selanjutnya dikonversi menjadi 10.000 New Dollar Taiwan/Ping. Hasil yang didapatkan berupa data actual dan data predicted yang divisualisasikan dengan line plot. Dilakukan juga uji akurasi dan uji kinerja pemodelan menggunakan 3 jenis evaluasi dengan hasil dari ketiga jenis evaluasi tersebut adalah 58,72 untuk skor MSE, skor 7,66 untuk RMSE dan 5,99 untuk skor MAE.
Synthesis of silicon quantum dots using chitosan as a novel reductor agent
Authors: Hernández-Abril P. A. , Iriqui-Razcón J. L. , León-Sarabia E. , Leal-Soto S. D. , Álvarez-Ramos M. E. , Berman-Mendoza D. , Higuera-Valenzuela H. J. 
Published: March 2021

In the present paper we report a novel synthesis method of silicon quantum dots (SiQDs) using 3-Aminopropyltriethoxysilane (APTES) as silicon precursor and low molecular weight chitosan (CS) as reducing agent. The obtained SiQDs have a hydrodynamic diameter of 2.3 nm, water dispersible, presents blue emission band at 434.5 nm (2.85 eV) with a Commission Internationale de l’Eclairage 1931 (CIE1931) chromaticity coordinates (x = 0.1665, y = 0.1222), the experimental absorbance of the SiQDS was measured and the band gap (Eg) was estimated through PerkinElmer’s method, the obtained value was 3.1 eV and a positive ζ-potential of + 35 mV, resulting in photonics, microelectronics, and biotechnological potential applications.
The temporal fluctuation of the inverse participation ratio for localized field modes in three-dimensional percolation system
Authors: Martínez-Sánchez E. , Díaz-de-Anda A. , Burlak G. , Muñiz-Valdez R. 
Published: March 2021

We investigate the structure of the optical field radiated by the disordered optical nano-emitters randomly incorporated in three-dimensional cluster of a percolation material. Our numerical studies shown that the temporal variations of the inverse participation ratio (IPR) allow analyzing the extended and localized field structures over a long time range. The properties of IPR and the dynamics of the lasing emitters allow to find the characteristic time scales when the localization of the field in a general three-dimensional disordered system occurs. The studied effect opens new perspectives to control the optical fields localization in modern optical nano-technologies.
Déterminants de la mortalité néonatale précoce dans une maternité de type 3 : à propos de 150 cas
Authors: Feirouz A. , Sdiri Y. , Cherifi E. , Chourou H. , Cheour M. , Bel Haj Ammar W. , Achour R. , Kacem S. 
Published: March 2021

Introduction : Le taux de mortalité néonatale précoce constitue un bon indicateur de la qualité des soins et du niveau de développement économique et social d’une population. Le but de notre travail est de déterminer la prévalence, le profil étiologique et les facteurs de risque de la mortalité néonatale précoce.
Méthodes : Il s’agit d’une étude rétrospective descriptive réalisée, au service de médecine et de réanimation néonatale du centre de maternité et de néonatologie de Tunis, sur une période de neuf mois de janvier à septembre 2017. Durant cette période, 3 560 nouveau-nés ont été hospitalisés dans ce service de réanimation néonatale. Au sein de cette cohorte, 150 patients sont décédés en période néonatale précoce.
Résultats : L’incidence de la mortalité néonatale précoce est de 15 pour mille naissances vivantes. Le taux de mortalité néonatale très précoce survenant les 24 premières heures de vie est de 15 % ; 60 % sont décédés au-delà de 48 heures de vie. Le taux de prématurité est de 68 %. Les principales causes de ces décès néonatals précoces sont une cause infectieuse dans 38,6 % des cas, soit une infection néonatale bactérienne précoce dans 25 % des cas, soit une infection nosocomiale secondaire dans 14 % des cas, une malformation congénitale (18,7 %) ou une asphyxie périnatale (APN) [12,7 %]. Les principaux facteurs de risque de mortalité néonatale précoce sont le non-suivi des grossesses, le bas niveau socio-économique, la prématurité, le faible poids de naissance, l’APN, les malformations cardiaques et du système nerveux central.
Conclusion : La mortalité néonatale précoce reste encore élevée. Pour essayer de la réduire, on insiste sur l’amélioration du suivi des grossesses, la prévention de la prématurité et l’amélioration des infrastructures néonatales.
WOMEN LANGUAGE FEATURES IN RECODE WORLD’S TECHNOLOGY CONFERENCE: A SOCIOLINGUISTIC STUDIES
Authors: DEBY RAHMAWATI  , Resmana Elvi Citra , Indrayani Lia Maulia 
Published: March 2021

This research analyzes the women language features in giving public speeches in RECODE World’s Technology Conferences. The writer used Lakoff’s on Holmes (2013) theory to analyze the data. The writer applies descriptive qualitative method by Creswell (2014). Data for this reseach is women utterance during conference. Basen on theory by Lakoff, the author discover six women language features.The result of this research shown that there are six women language feature that appear, there are lexical hedges, intensifier, superpolite form, avoidance strong swear, empty adjective, and emphatic stress.
Keyword: sociolinguistics, gender language, women language features.
REPRESENTASI KARAKTER TOKOH DALAM CERPEN RUSA-RUSA MASUK KACA KARYA MOSTHAMIR THALIB: PENDEKATAN SEMIOTIK CHARLES SANDERS PEIRCE
Authors: Sum Tengku Muhammad 
Published: March 2021

This research has been motivated by literature as reflection of reality. The story ”Rusa-Rusa Masuk Kaca” is selected because the character in the story presents reality. The study of this story uses Charles Sanders Peirce’s semiotic analysis. Namely sign, object, and interprentrant. Semiotic analysis is used to analyze character representation that connect literary work with reality. The method used is qualitative descriptive with a literature study of data collection techniques.
Keywords: Short Stories Rusa-Rusa Masuk Kaca, Semiotic Peirce, Character Representation.
Synergistic Effects of APOE and CLU May Increase the Risk of Alzheimer’s Disease: Acceleration of Atrophy in the Volumes and Shapes of the Hippocampus and Amygdala
Authors: An Na , Fu Yu , Shi Jie , Guo Han-Ning , Yang Zheng-Wu , Li Yong-Chao , Li Shan , Wang Yin , Yao Zhi-Jun , Hu Bin ,   Alzheimer’s Disease Neuroimaging Initiative
Published: March 2021

Background: The volume loss of the hippocampus and amygdala in non-demented individuals has been reported to increase the risk of developing Alzheimer’s disease (AD). Many neuroimaging genetics studies mainly focused on the individual effects of APOE and CLU on neuroimaging to understand their neural mechanisms, whereas their synergistic effects have been rarely studied. Objective: To assess whether APOE and CLU have synergetic effects, we investigated the epistatic interaction and combined effects of the two genetic variants on morphological degeneration of hippocampus and amygdala in the non-demented elderly at baseline and 2-year follow-up. Methods: Besides the widely-used volume indicator, the surface-based morphometry method was also adopted in this study to evaluate shape alterations. Results: Our results showed a synergistic effect of homozygosity for the CLU risk allele C in rs11136000 and APOE ɛ4 on the hippocampal and amygdalar volumes during a 2-year follow-up. Moreover, the combined effects of APOE ɛ4 and CLU C were stronger than either of the individual effects in the atrophy progress of the amygdala. Conclusion: These findings indicate that brain morphological changes are caused by more than one gene variant, which may help us to better understand the complex endogenous mechanism of AD.