bluuebunny/crossref_metadata_2025_split huggingface dataset:
ЦИФРОВОЕ СЕЛЬСКОЕ ХОЗЯЙСТВО: МЕХАНИЗМ ВНЕДРЕНИЯ НА ОСНОВЕ ПРОГРЕССИВНЫХ ТЕХНОЛОГИЙ И ЕГО ФИНАНСОВОЕ ОБЕСПЕЧЕНИЕ
Authors: Гасанов Гасан Атабабаевич , Гасанов Тофик Атабабаевич , Эминова Эльнара Мигажидиновна 
Published: October 2021

Цель работы. Исследовать механизм реализации проекта ЦСХ на основе анализа разделов проекта и его финансового обеспечения. На основе детального рассмотрения III и IVразделов проекта ЦСХ был выявлен важный механизм реализации проекта на основе технологии «блокчейн». Рассмотрены финансовые показатели, обеспечивающие их функционирование и сбалансированность с другими разделами ЦСХ. Метод или методология проведения работы. В процессе анализа разделов ЦСХ был использован метод логических абстракций, причинно-следственный метод, метод функционального анализа, который позволил рассмотреть взаимозависимости основных финансово-экономических показателей по разделам проекта ЦСХ. Результаты. В процессе рассмотрения механизма функционирования ЦСХ было выявлено, что с помощью многообразных подсистем создана производственно-потребительская цепочка, с помощью которой действует технология «блокчейн», эта технология имеет значительные преимущества за счет использования цифровых технологий, искусственного интеллекта и других прогрессивных технологий. При подготовке специалистов в области цифровой экономики для сельхозпредприятий был выявлен дисбаланс в части планируемых средств по отношению к другим пунктам и разделам ЦСХ. Область применения результатов. Выявленный механизм технологии блокчейн в результате реализации ЦСХ может быть использован при планировании региональных проектов ЦСХ или его отдельных разделов, крупными аграрными объединениями; в процессе преподавания по курсу «Цифровая экономика», отдельных разделов «Анализ хозяйственной деятельности», «Экономика организации (предприятия)». Выводы. Полученные данные и обобщения свидетельствуют: о преимуществах и больших возможностях новой технологии блокчейн; необходимости корректировки отдельных пунктов и разделов ЦСХ в результате выявленного дисбаланса по подготовке специалистов сельхозпредприятий в области цифровой экономики; о влиянии внешних факторов – эпидемии коронавируса, мирового экономического кризиса, которые могут повлиять на процесс внедрения ЦСХ.
“They shall not grow old” and “Mimesis: African soldier”
Authors: Voeltz Richard A. 
Published: October 2021

This paper will examine and compare two recent visual explorations of the experience of soldiers in World War I. Director Peter Jackson’s documentary They Shall Not Grow Old has been called an immersive, haunting and often transcendent experience that’s unlike anything you’ve ever seen before. By using modern digital film technology, he has restored the visuals and added sounds and speech via Automatic Dialogue Replacement, colorized, changed the speed, and brought 3D depth to the old footage from the Imperial War Museum. Jackson has either, using the terminology of William Guynn (Unspeakable Histories: Film and the Experience of Catastrophe), employed this technology to trigger “moments of heightened awareness in which the reality of the past may be recovered in its material being”. Or, do these computer generated technological affects, “….stand in for the ‘truth’ and obscure just how constructed the ‘history’ Jackson is telling actually is?” John Akomfrah’s video/sound three screen performance/display installation Mimesis: African Soldier uses silent actors, archive film and photographs, ethnographic sound recordings, new filmed footage with and without actors, and a sound track by Trevor Mathison, to document the experience of those, among many, left out of Jackson’s film: colonial subjects as soldiers. Akomfrah “does not put colour back in the cheeks of the dead”, but rather warns the viewer that remembrance can come in many forms, some of them unrealiable. All of this leads to a conclusion, as Avishai Margalit put it in Ethics of Memory, that “memory…is knowledge from the past. It is not necessarily knowledge about the past.”
Increasing community participation during the COVID-19 Pandemic by developing a 5-pillar empowerment strategy
Authors: Luthfianto Saufik , Imron Muhammad , Maulida Nurul , Triatmaja Yosea 
Published: October 2021

The objective of this study is to increase community participation by developing a 5-pillar empowerment strategy in Pepedan village, Moga sub-district, Pemalang regency. These policies include education, health, economy, environment and Pancasila ideology. Field observations, interviews, pre-test, socialization and post-test served as the research methods. The results showed an improvement in community participation by 15.25, 9.54, 48.2, 35.7 and 38.12% in education, health, economic, environmental and the Pancasila ideology frameworks, respectively.
The dissemination of Mendeley application for citations and bibliographies
Authors: Sastradipraja Cecep Kurnia , Murwenie Ira , Karim Khobir Abdul , Solihin Hanhan Hanfiah , Erfina Adhitia , Sembiring Falentino 
Published: October 2021

The purpose of this community empowerment is to provide useful information to enable students write effective scientific papers. Adequate guidance on the practical application of Mendeley reference management system was incorporated. This activity was conducted online using Zoom and commenced with a discussion on scientific works, paraphrasing techniques, and subsequently ended by analyzing Mendeley reference management system and its application. A total of 438 participants were recorded in the survey with 70.14% of them reacted positively to the event. Furthermore, the activity is expected to continue in the future, with broader discussions on related topics.
A training on the development of adaptive digital learning materials to improve teachers’ competence during the COVID-19 pandemic
Authors: Aryani Dewi Isma , Pandanwangi Ariesa , Ida Ida , Manurung Rosida Tiurma , Pattipawaej Olga Catherina 
Published: October 2021

The COVID-19 pandemic has altered the education order towards a virtual experience. Also, the use of digital media appears convenient for conveying learning materials and engaging students effectively. Under this circumstance, elementary school teachers commonly encounter certain difficulties using online platforms, due to poor knowledge of technology. Therefore, the objectives of this study are to: 1) strengthen educators' ability in mastering technology for distance learning, and 2) improve cooperation and reputation of the Maranatha Women's Family Association to the wider community. An asset-based community development (ABCD), using a mentoring and practical approach was adopted. This study was conducted online, with an attendance of 50 elementary school educators in Tangerang. The results showed that the participants gained significant insights and practical techniques for developing distance learning materials using power point slides to support the online learning process.
ANEMIA IN SICKLE CELL TRAIT
Authors: Khanam Bushra , Singh Srajit , Saraf Manish Kumar , Gautam Rudraksh 
Published: October 2021

Background & Method: Subjects for the study were recruited from the rural comprehensive sickle cell program at Index Medical College Hospital & Research Centre, Indore. These patients were followed up with regularly at the comprehensive sickle cell clinic with all relevant clinical and laboratory data documented in detailed case report forms. Patients were advised to follow up on a monthly basis or as symptoms presented.
Result: In our study we found, maximum no of cases in age group of 01-15 (45.6%) followed by 16-30 (30.6%)
In our study we found 11 males >18years & 19 males <18 years & 11 females >18 years & 05 females <18 years.
Conclusion: We provide for the first time detailed prevalence data of the ?s gene among Rural Population ethnic groups in Central India. These population screening programs have uncovered previously undiagnosed cases, provided detailed information for population based disease counseling, prevention programs and comprehensive care programs. Over 5,000 individuals were identified with SCT and more than 1,000 individuals were identified with SCD through community-based and target high-risk screening. The population screening study shows how community-based screening can identify individuals who may not have otherwise sought care and guide individuals to available comprehensive care centers. The screening also helped identify specific sub-groups within the Rural Population that have higher prevalence rates of the ?s gene. An estimated 1.1 million individuals in the state of Madhya Pradesh alone are expected to have SCT. Similar community-based screening programs need to be initiated throughout regions of India that have a high prevalence of Rural Population to determine the true prevalence of the ?s gene in India.
In summary, there appeared to be a broad general knowledge of sickle cell disease in the identified. target samples, with many 1nteresting comparative responses to the attitudinal survey, but no statistically significant differences 1n black and white responses in western countries.
That all persons experiencing genetic disease have the option to choose genetic counseling and sufficient community education to know they have this choice. That all genetic counseling include supportive family therapy and education over a sufficient period of time so the family can integrate the information into their own life systems.
Keywords: Anemia, Sickle & Trait.
Daun Dewa (Gynura Pseudochina (Lour) Dc) Jelly Candy Making with Addition of Gelling Agents (Alginate, Carrageenan, And Gum Arabic) in Various Concentrations
Authors: Fesdila Putri Nurani  , Pratiwi Eka Murliati  , Dedin Finatsiyatull Rosida  
Published: October 2021

Jelly candy is generally made from fruit juice with some hydrocolloid addition in order to the gelling formation. The characteristic of jelly candy is a clear and transparent appearance with chewiness in texture. To increase its functional value, jelly candy can be added with various ingredients, for example, the extract of Daun Dewa (Gynura Pseudochina (Lour) Dc). Daun Dewa (Gynura Pseudochina (Lour) Dc) contains some active components such as alkaloids, flavonoids, essential oils, saponins, and steroids, triterpenoids, and tannins, where these compounds show antioxidant activity. One parameter on jelly candy making was the gelling formation influenced by the hydrocolloid or gelling agent's existence. Some gelling agent that has been used in commercial jelly candy-like alginate, carrageenan and Gum Arabic. The combination of those gelling agents with various concentrations would give the different characteristics of jelly candy. This study aimed to observe the characteristic of jelly candy with the addition of gelling agents and determine the best treatment that most liked by the panelists. The concentration of gelling agents used in this study was 0, 2.5%, 5%, 7.5%, and 10% (w/v) with a single factor of Simple Completely Randomized Design (CRD). The data analyzed using ANOVA. Based on the result, the best treatment of Daun Dewa jelly candy was made with the addition of 7.5% carrageenan and 2.5% gum Arabic that has moisture content value of 16.742%, ash content 0.685%, reducing sugar 20.273%, total phenol 11.078 mg TAE / gr, pH 4.27, gel strength 46.3788 N, antioxidant 32.536%, and sensory evaluation covering 4.96 for color, 4.28 for aroma, 4.60 for texture, and 4.88 for taste.
The Effect of Resin and NH4OH Addition in The Making of Ammonium Silica Fertilizer from Geothermal Sludge
Authors: Nurma Wahyusi Kindriari , Nandini Atika , Indrati Utami Lucky , Siswanto  , Utami Isni , Mardhiyah Nurul , Nofita Dian 
Published: October 2021

Geothermal sludge is a waste product from geothermal where it contains SiO2 which can be used as fertilizer. In this study, the making of silica ammonium fertilizer was carried out by taking salicy acid from geothermal sludge by extracting and adding resin which was then modified with NH4OH addition. Extraction was done using 1000 ml of KOH 1 N to dissolve 60 grams of Geothermal Sludge. Resins are added with variations in resin weight, namely, 5, 10, 20, 30, and 40 grams. NH4OH was added with variations in concentrations namely 3, 6, 9, 12 and 15% with a ratio of filtrate and NH4OH solution of 1: 1. The resulting ammonium silica inorganic liquid fertilizer products were analyzed for free silica and ammonia levels. The results of this study indicate that the levels of free silica and ammonia are influenced by the weight of the resin used and the concentration of ammonium hydroxide mixed. From the results of the research, it was found that inorganic silica liquid fertilizer with the highest SiO2 content in ammonium silica liquid fertilizer occurred when adding 20 grams of resin with the addition of NH4OH with a concentration of 15% which was 1,831.87 mg / L while the highest NH3 content in fertilizer liquid ammonium silica occurs when adding 40 grams of resin with the addition of NH4OH with a concentration of 15% which is equal to 252,312.80 mg / L.
Aplikasi Monitoring Energi SHS Off-Grid Menggunakan Lora
Authors: Yudho Satrio 
Published: October 2021

The manner of efficiency and effective of power usage is the main objective in electricity consumption, one major steps to control the usage is by providing a monitoring to aim the power usage data and process it to information needed. Internet of Things benefit in power and electricity has involved sensors to work as data reader continuously. LoRa or well known as Long Range radio communication system work with chirp spread spectrum which work from 920 to 923 Mhz in Indonesia. This paper presents implementation of LoRa system to support the prototype of energy monitoring in Solar Home System off-grid
Sistem Informasi Klinik Berbasis Website Menggunakan Metode Extreme Programming (Studi Kasus Klinik Karunia Bunda)
Authors: BANJARNAHOR DONDA 
Published: October 2021

Klinik merupakan kebutuhan setiap manusia sebagai tempat atau sarana yang berfungsi untuk membantu memberikan pelayanan kesehatan masyarakat. Apabila klinik belum menggunakan sistem komputerisasi, maka akan menghambat proses penanganan pasien. Pada Klinik Karunia Bunda ditemukan hambatan, diantaranya pendaftaran pasien masih dilakukan secara manual dengan pasien harus datang langsung ke klinik, tidak memiliki sistem antrian dalam perawatan, manajemen rekam medis yang masih manual dengan menulis tangan. Hal ini dapat membutuhkan banyak waktu dalam proses pencarian data. Tujuan dari aplikasi ini adalah memudahkan kegiatan operasional sehari-hari di dalam klinik yang berjalan dengan cepat dan tepat, serta pengelolaan data medis akan lebih akurat (meminimalisir human error). Metode analisa menggunakan Soft System Methodology (SSM), dan metode pengembangan sistem menggunakan Extreme Programming (XP). Aplikasi ini berbasis website menggunakan bahasa pemrograman PHP dalam framework Codeigniter (CI) yang didukung basis data MySQL. Diharapkan dengan aplikasi ini proses kerja di dalam klinik menjadi lebih cepat, pendokumentasian rekam medis yang terstruktur, mengurangi penggunaan kertas, serta memudahkan aktivitas dalam pelayanan pasien.
Kata kunci : Klinik, Website, Soft System Management (SSM), Extreme Programming (XP).
Selenium and Zinc Oxide Multinutrient Supplementation Enhanced Growth Performance in Zebra Fish by Modulating Oxidative Stress and Growth-Related Gene Expression
Authors: Fasil Dawit Moges , Hamdi Hamida , Al-Barty Amal , Zaid Abeer Abu , Parashar S. K. S. , Das Biswadeep 
Published: October 2021

Selenium and zinc are important dietary micronutrients having antimicrobial and antioxidant roles, thereby assisting in normal development, and an enhanced immune system. Supplementation of selenium and zinc for enhancing the growth performance and reproductive capacity in fish was explored in this study. Selenium nanoparticles (SeNPs) and zinc oxide nanoparticles (ZnONPs) were synthesized by high-energy ball milling (HEBM) using a 10-h dry milling technique at a 10:1 ball-to-powder ratio (BPR) and were premixed with basal feed followed by the administration to adult zebra fish (D. rerio) (2 months old) for 30 days. Growth analysis revealed that zebra fish fed with SeNPs + ZnONPs (2 mg/ kg, equimolar mixture) had significantly higher length and weight than only SeNP (2 mg/ kg) or ZnONP (2 mg/ kg) groups and control zebra fish (p &lt; 0.05). The average length–weight relationships were assessed by estimating the condition factor (C), which was highest in the SeNP + ZnONP group (1.96), followed by a downward trend in SeNP (C = 1.15) and ZnONP (1.11) (p &lt; 0.05). Relative gene expression of growth hormone and insulin-like growth factor-1 was significantly high in the SeNP + ZnONP group compared to other groups (p &lt; 0.05), which indicated that combined administration of both the nanoparticles in basal feed enhanced the growth performance of zebra fish. Intracellular ROS generation was low in the combined group, followed by control, SeNP, and ZnONP groups, indicating higher concentrations of both nanoparticles, in particular, ZnONPs induced oxidative stress. Fecundity and the development of fertilized embryos were significantly high in the SeNP + ZnONP–treated zebra fish compared to only the SeNP- or ZnONP-treated group or control (p &lt; 0.05). These findings indicated that supplementation of SeNP + ZnONP in basal feed could considerably improve the growth performance and development of zebra fish which could be exploited for enhancing aquaculture production.
Survival-Related lncRNA Landscape Analysis Identifies LINC01614 as an Oncogenic lncRNA in Gastric Cancer
Authors: Wu Huijie , Zhou Jingyuan , Chen Songda , Zhu Lingyu , Jiang Mengjie , Liu Aiqun 
Published: October 2021

Background: Long non-coding RNAs (lncRNAs) reportedly play important roles in biomarker and tumorigenesis of gastric cancer (GC). This study aimed to determine the potential application of prognostic lncRNA signature and identified the role of LINC01614 in carcinogenesis in GC.Material and Methods: Data accessed from the Cancer Genome Atlas database was used to construct a lncRNA signature. Joint effect analysis of the signature and clinical parameters was performed to verify the clinical value of the signature. Co-expression analysis was conducted for prognostic lncRNAs and protein-coding genes. Moreover, the relative expression of LINC01614 was validated in GC tissues and cell lines. In vitro and in vivo experiments were conducted to analyze the biological functions of the newly identified gene in GC cells.Results: A seven-lncRNA (LINC01614, LINC01537, LINC01210, OVAAL, LINC01446, CYMP-AS1, and SCAT8) signature was identified as a promising prognostic signature in GC. Results indicated that the seven-lncRNA was involved in tumorigenesis and progression pathways. LINC01614 expression was identified and found to be upregulated in GC tissues and cells. The study findings revealed that LINC01614 promoted cell proliferation, migration, invasion, and epithelial-mesenchymal transition. Knockdown of LINC01614 arrested cell cycle distribution at the G2/M phase. Further, LINC01614 also promoted tumor growth in vivo.Conclusion: We developed an independent seven-lncRNA biomarker for prognostic prediction and identified LINC01614 as an oncogenic lncRNA in GC.
The Frequency of DNA Mismatch Repair Deficiency Is Very Low in Surgically Resected Lung Carcinoma
Authors: Yanagawa Naoki , Yamada Noriyuki , Sugimoto Ryo , Osakabe Mitsumasa , Uesugi Noriyuki , Shiono Satoshi , Endoh Makoto , Ogata Shin-ya , Saito Hajime , Maemondo Makoto , Sugai Tamotsu 
Published: October 2021

IntroductionDNA mismatch repair (MMR) deficiency leads to changes in the length of nucleotide repeat sequences of tumor DNA. In that situation, DNA replicational errors occur and accumulate during DNA replication. As a result, this mechanism frequently affects the coding regions of oncogenes and tumor suppressor genes and causes carcinogenesis. Recently, DNA MMR deficiency has been recognized as a predictive biomarker for immunotherapy. The aim of this study is to examine the frequency of DNA MMR deficiency and clinicopathological characteristics in surgically resected lung carcinoma (LC) and their correlation.MethodsA total of 1153 LCs were examined. Tissue microarrays were constructed. The status of MMR deficiency was evaluated by immunohistochemical analysis of MMR protein expression (hMLH1, hMSH2, hMSH6, and hPMS2). Microsatellite instability analysis, BRAF mutation, and MLH1 methylation analysis were performed for cases that showed MMR deficiency.ResultsOnly 2 of the 1153 cases (0.17%) showed a loss of hMLH1/hPMS2 protein expression. They also had high levels of microsatellite instability (MSI-H), had neither MLH1 promoter methylation nor BRAF mutation, and were male smokers. Histopathologically, one was a squamous cell carcinoma, and the other was combined small cell carcinoma with squamous cell carcinoma. Regarding PD-L1 protein expression, one had high expression, and the other had none.ConclusionThe frequency of MMR deficiency was very low in LC. However, our two cases were non-adenocarcinoma and differed from previous studies. Because of its very low frequency, MMR deficiency is not a practical biomarker to predict the effect of immune checkpoint inhibitors in LC.
Network Pharmacology to Explore the Molecular Mechanisms of Prunella vulgaris for Treating Hashimoto’s Thyroiditis
Authors: Gan Xiao-xiong , Zhong Lin-kun , Shen Fei , Feng Jian-hua , Li Ya-yi , Li Si-jing , Cai Wen-song , Xu Bo 
Published: October 2021

Purpose:Prunella vulgaris (PV), a traditional Chinese medicine, has been used to treat patients with thyroid disease for centuries in China. The purpose of the present study was to investigate its bioactive ingredients and mechanisms against Hashimoto’s thyroiditis (HT) using network pharmacology and molecular docking technology to provide some basis for experimental research.Methods: Ingredients of the PV formula were retrieved from the Traditional Chinese Medicine Systems Pharmacology (TCMSP) database. Additionally, HT-related genes were retrieved from the UniProt and GeneCards databases. Cytoscape constructed networks for visualization. A protein–protein interaction (PPI) network analysis was constructed, and a PPI network was built using the Search Tool for the Retrieval of Interacting Genes (STRING) database. These key targets of PV were enriched and analyzed by molecular docking verification, Gene Ontology (GO), and Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment.Results: The compound–target network included 11 compounds and 66 target genes. Key targets contained Jun proto-oncogene (JUN), hsp90aa1.1 (AKI), mitogen-activated protein kinase 1 (MAPK1), and tumor protein p53 (TP53). The main pathways included the AGE-RAGE signaling pathway, the TNF signaling pathway, the PI3K–Akt signaling pathway, and the mitogen-activated protein kinase signaling pathway. The molecular docking results revealed that the main compound identified in the Prunella vulgaris was luteolin, followed by kaempferol, which had a strong affinity for HT.Conclusion: Molecular docking studies indicated that luteolin and kaempferol were bioactive compounds of PV and might play an essential role in treating HT by regulating multiple signaling pathways.