bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGENALAN TEKNIS PENULISAN KARYA TULIS ILMIAH DAN BIMBINGAN TEKNIS PENERBITAN ARTIKEL PADA JURNAL ILMIAH BAGI GURU-GURU SD,SMPN 6 SATAP DI KECAMATAN SEPAUK
Authors: Wibowo Dwi Cahyadi 
Published: May 2021

ABSTRAKKurangnya pemahaman bagaimana melakukan penelitian tindakan kelas memicu realita bahwa guru masih enggan melaksanakan penelitian. Guna membantu guru dalam meningkatkan kompetensi dalam melaksanakan penelitian tindakan kelas, maka tim PKM STKIP Persada Khatulistiwa Sintang melakukan pendampingan dan bimbingan dalam melaksanakan penelitian tindakan kelas serta melakukan pendampingan teknis bagi para guru untuk dapat mempublikasi hasil penelitiannya. Secara umum kegiatan PKM ini dilaksanakan dengan metode pelatihan berupa presentasi dan penjelasan tentang metodologi PTK serta bimbingan teknis publikasi jurnal ilmiah dengan metode pelaksanaan kegiatan secara daring. Kegiatan ini diikuti oleh 20 guru SD-SMPN 6 Kecamatan Sepauk Kabupaten Sintang. Luaran kegiatan pengabdian yang dilakukan di SD-SMPN 6 SATAP Sepauk mencapai target yang direncanakan. Kegiatan PKM ini diikuti oleh lebih dari 80% guru dari SD-SMPN 6 SATAP Sepauk, walaupun tidak 100% dari jumlah tersebut dapat mengikuti dari awal kegiatan karena kendala jaringan internet. Selama kegiatan berlangsung respon para guru sangat baik terhadap kegiatan PKM ini. Para guru menjadi bersemangat untuk melakukan penelitian dan beberapa diantaranya berupaya melakukan penelitian untuk kenaikan pangkatnya serta setidaknya ada kurang lebih 30% guru berniat mengadakan kolaborasi penelitian dengan para anggota PKMKata Kunci: Pengenalan Teknis; Bimbingan Teknis; Karya Tulis Ilmiah ABSTRACTA lack of understanding of how to conduct classroom action research triggers the reality that teachers are still reluctant to carry out research. PKM team of STKIP STKIP Persada Khatulistiwa Sintang provides assistance and guidance in carrying out classroom action research and provides technical assistance for teachers to be able to publish their research results. In general, this PKM was conducted with training methods in the form of presentations and explanations of the CAR methodology as well as technical guidance for scientific journal publications with methods of implementing activities online. This activity was attended by 20 teachers from SD-SMPN 6, Sepauk District, Sintang District. The output of the service activities carried out at SD-SMPN 6 SATAP Sepauk achieved the planned target. This PKM activity was attended by more than 80% of teachers from SD-SMPN 6 SATAP Sepauk, although not 100% of this number were able to participate from the beginning of the activity due to internet network problems. During the activity, the teachers responded very well to this PKM activity. The teachers are excited to do research and some of them try to do research for promotion and at least 30% of the teachers intend to conduct research collaborations with PKM members.Keywords : Technical Introduction; Technical guidance; Scientific papers
Low Risk of Severe Complications After a Single, Post-Operative Instillation of Intravesical Chemotherapy in Patients with TaG1G2 Urothelial Bladder Carcinoma
Authors: van Hoogstraten Lisa M.C. , Witjes J. Alfred , Ripping Theodora M. , Nooter Ronald I. , Kiemeney Lambertus A. , Aben Katja K.H. ,   on behalf of the BlaZIB study group
Published: April 2021

BACKGROUND: EAU guidelines recommend a single instillation (SI) of intravesical chemotherapy (e.g. Mitomycin C) within 24 hours after transurethral resection of a bladder tumour (TURBT) in patients with low- to intermediate risk non-muscle invasive bladder cancer without (suspected) bladder perforation or bleeding requiring bladder irrigation. However, remarkable variation exists in the use of SI. The risk of severe complications is likely to contribute to this variation, but evidence is limited. OBJECTIVE: To investigate the absolute severe complication and mortality risk after SI in low- and intermediate risk bladder cancer. METHODS: In this observational, historic cohort study, data on 25,567 patients diagnosed with TaG1G2 urothelial bladder carcinoma (UBC) between 2009 and 2018 who underwent TURBT were collected from the Netherlands Cancer Registry. Data were supplemented with information on cause of death and severe complications after cancer treatment by re-examining the electronic health records and the 14-day complication risk and the 30-day mortality risk were evaluated. RESULTS: On average, 55% of patients had a SI after TURBT, varying from 0–>80% between hospitals. The 30-day mortality risk was 0.02% and the 14-day risk of severe complications was 1.6%. CONCLUSIONS: As the absolute risk of mortality and severe complications is very low, SI after TURBT can be considered a safe treatment in patients with low- to intermediate UBC without contraindications for SI. These results imply that a part of eligible patients is denied effective treatment.
Effect of cerebrolysin on neurodevelopmental outcome of high risk preterm infants: A randomized controlled trial
Authors: Samir A. , Nasef N. , Fathy K. , El-Gilany A-H. , Yahia S. 
Published: April 2021

BACKGROUND: A significant proportion of preterm infants experience developmental delay despite receiving a post discharge early interventional care. Cerebrolysin is a peptide mixture which acts similar to endogenous neurotrophic factors through promoting neurogenesis and enhancing neuronal plasticity. OBJECTIVE: To compare the effect of Cerebrolysin plus routine intervention program versus routine intervention program alone on the outcome of preterm infants at high risk for neurodevelopmental delay. METHODS: In a randomized controlled trial, high-risk preterm infants < 32 weeks’ gestation who have abnormal neurological assessment at two months corrected post-natal age were randomized at 6 months corrected post natal age to receive either early intervention program or early intervention program plus Cerebrolysin injection of 0.1 mL/kg body weight every week for 3 months as an adjuvant therapy. The primary outcome was the rate of failure of the gross motor assessment at 12 months of corrected age and secondary outcomes included fine motor, language, and personal social development at 12 months corrected post-natal age as assessed by Denver Developmental Screening Test II. RESULTS: Cerebrolysin group had a significant lower number of infants diagnosed with failed gross motor development compared to infants in the routine intervention group [10 (33%) versus 21 (70%), p = 0.009]. Cerebrolysin group had a significant lower number of infants diagnosed with failed fine motor, language and personal social development compared to infants in the routine intervention group. CONCLUSION: Cerebrolysin, as an adjuvant therapy to routine early interventional care, may improve gross motor development of high-risk preterm infants at 12 months corrected post-natal age.
Bleeding cervical varices in pregnancy: A case report and review of the literature
Authors: Poliektov Natalie , Kahn Bronwen F. 
Published: April 2021

BACKGROUND: Venous varicosities are a relatively common finding during pregnancy. Rarely, varices can arise in the cervix and cause life-threatening maternal hemorrhage. This article offers an example of a patient who was diagnosed with bleeding cervical varices during pregnancy and summarizes the diagnosis and treatment strategies for the 20 other reported cases in the literature. METHODS: A PubMed literature search using the following terms was performed to gather data for the literature review: “bleeding” or “hemorrhage” and “cervical varices” or “cervical varix” or “cervical varicosities” and “pregnancy” or “obstetric” or “maternal.” Individual references cited in each article were also evaluated for inclusion in this review. RESULTS: A 50-year-old gravida 7 para 1 presented at 12 4/7 weeks with vaginal bleeding. Endo-vaginal ultrasound showed enhanced color Doppler signal in the endocervical canal. During a speculum exam, she was found to have active bleeding from ruptured cervical varicosities and required blood and fresh frozen plasma transfusion. Hemostasis was achieved with interrupted suture ligation. A McDonald cerclage was subsequently placed. She continued pregnant until delivery via cesarean section at 37 2/7 weeks. To date, there have only been 20 other reported cases of bleeding cervical varices during pregnancy. CONCLUSIONS: This case report and review of the literature highlight the importance of including bleeding cervical varices in the differential diagnosis of maternal hemorrhage and offer a treatment strategy if cervical varicosities are discovered during pregnancy.
Thrombosis of the abdominal aorta in newborn: About two cases
Authors: Imad N. , El Idrissi Slitine N. , Alaoui S. , Zalle I. , Boumzebra D. , Bennaoui F. , Maoulainine F.M.R. 
Published: April 2021

BACKGROUND: Aortic thrombosis in neonates is a rare phenomenon, and in most cases iatrogenic. An early recognition of the clinical features and an immediate intervention can offer a better prognosis, and thus preventing morbidity such as limb amputation, and even mortality. METHODS: We present two cases of full-term newborns with a thrombosis of the abdominal aorta hospitalized in the neonatal intensive care unit of Mohammed VI University Hospital in Marrakech in 2017 and 2019. RESULTS: The two patients presented swelling and cyanotic lower limbs. Doppler ultrasound revealed a pathological lower limb blood flow as a result of a thrombosis of the abdominal aorta. Both patients underwent an anticoagulant therapy, the first one benefited from a surgical thrombectomy, he developed a reperfusion syndrome with alveolar hemorrhage, and passed away as a result of a cardiorespiratory arrest. However the second patient got amputated of the right foot, his clinical evolution was favorable with a good healing of the surgical wound without recurrence of any thrombosis. CONCLUSION: Through those cases clinicians should be aware of the first clinical signs of this condition in order to offer a rapid and successful management.
Blood melatonin level can serve as a potential biomarker for prostate and hepatocellular carcinomas
Authors: Sartorelli Lorenzo Silvestrin , Neto Rubens José Bombardi , Mosqueta-Pinheiro Marina Gobbe , De Castro Tialfi Bergamin , Fernandes Fabio Leite Couto , Silva Renato , Novais Adriana Alonso , Chuffa Luis Gustavo De Almeida , Reiter Russel J , Zuccari Débora Aparecida Pires de Campos 
Published: April 2021

Many systemic functions display circadian rhythms driven by an endogenous mechanism that is regulated by circadian-related genes and these gene expressions control a central clock in the brain and subordinate clocks in peripheral tissues. However, modern life has introduced environmental factors that often interfere with natural circadian rhythms. Importantly, circadian disruption has been identified as an independent risk factor of cancers. Melatonin is a major circadian rhythm regulator. In cancer patients, the rhythm of melatonin is often disrupted and its level is also reduced. These changes of melatonin impair its antioxidant and circadian regulatory functions on cells and tissues making them more susceptible to mutations and cancer initiation. In this context, the objectives of this study are to evaluate the sleep quality and blood levels of melatonin in patients with either prostate cancer (PC) or hepatocarcinoma (HCC) with the intent of using its levels as a potential biomarker of the cancers. The study involved 20 PC and 18 HCC patients, and 26 healthy volunteers. All blood samples were collected in the early morning, at 07:00 hours. Comparative sleep quality between PC, HCC patients and control subjects was acessed with a questionnaire, and melatonin and vitamin D were measured using conventional assays. The results revealed that patients with the worse sleep quality also had lower values of melatonin and vitamin D compared to control subjects. Notably, expression of melatonin-synthesizing enzymes and specific clock genes (PER, CRY and BMAL1) were significantly reduced and associated with worse prognosis in PC and HCC patients. These findings are consistent with the results of previous studies and suggest that disruption of the circadian rhythms, associated with changes in the light:dark cycle, has consequences for the maintenance of systemic health. We suggest that supplementation of melatonin and vitamin D may represent the important therapeutic strategies for patients with solid tumors for the purpose of improving their sleep quality and recuperative capacity.
PENGARUH PENGETAHUAN, SANKSI, PELAYANAN DAN KESADARAN WAJIB PAJAK TERHADAP KEPATUHAN WAJIB PAJAK DALAM MEMBAYAR PAJAK BUMI DAN BANGUNAN DI KECAMATAN MEDAN TUNTUNGAN
Authors: Reza Radhi Anshari  
Published: April 2021

This research aimed to find out the effect of tax knowledge, tax penalties, tax services and taxpayers’ awareness on taxpayers’ obligation in paying Land and Building Tax (PBB) in Kecamatan Medan Tuntungan. The samples in this reseach were 100 individual taxpayers registered in the region of Kecamatan Tuntungan. Data analysis technique was multiple linear regression analysy. The result of the reseach showed that tax services and taxpayers’ awareness had significant effect on taxpayers’ obligation. Meanwahile tax knowledge and tax penalties had no significant effect on taxpayers compliance.
ANALISIS KELAYAKAN USAHA TERNAK SAPI POTONG DI DESA SEI LITUR TASIK KECAMATAN SAWIT SEBERANG KABUPATEN LANGKAT
Authors: Nurlaila Hanum  , Miswar  , Utari Amanda  
Published: April 2021

Penelitian ini bertujuan untuk mengetahui kelayakan usaha ternak sapi potong di Desa Sei Litur Tasik Kecamatan Sawit Seberang Kabupaten Langkat. Penelitian ini dilaksanakan pada bulan November 2020 sampai dengan Maret 2021. Jenis data penelitian ini adalah kualitatif dan kuantitatif. Sumber data yang dikumpulkan berupa primer diperoleh melalui observasi, wawancara dan kuesioner, dan data sekunder yang di peroleh dari Badan Pusat Statistik dan Kantor Desa. Sampel penelitian ini adalah para peternak sapi potong di Desa Sei Litur Tasik yang berjumlah 80 responden dengan menggunakan metode analisis data Purposive Sampling. Metode analisis yang digunakan adalah R/C ratio dan B/C ratio, untuk mengetahui kelayakan usaha ternak sapi potong maka hasil penelitian menunjukan bahwa: (1) Kelayakan usaha R/C ratio pada usaha ternak sapi potong yang menunjukan besar nya total rata-rata penerimaan sebesar Rp 30.000.000/tahun, besarnya total rata-rata biaya sebesar Rp 8.185.501/tahun dan hasil perhitungan kelayakan usaha ternak sapi potong maka di peroleh dengan nilai R/C ratio sebesar 3,7 sehingga usaha ternak sapi potong memiliki kelayakan untuk diusahakan dan dijalankan. (2) Kelayakan usaha B/C ratio, memiliki total rata-rata pendapatan sebesar Rp 21.814.499/tahun, total rata-rata biaya sebesar Rp 8.185.501/tahun dan nilai B/C ratio sebesar 2,7 sehingga usaha ternak sapi potong layak dan menguntungkan untuk di kembangkan.
Medication Intake, Perceived Barriers, and Their Correlates Among Adults With Type 1 and Type 2 Diabetes: Results From Diabetes MILES – The Netherlands
Authors: Hogervorst Stijn , Adriaanse Marce C. , Hugtenburg Jacqueline G. , Bot Mariska , Speight Jane , Pouwer Frans , Nefs Giesje 
Published: April 2021

PurposeThe purpose of this study is to investigate medication intake, perceived barriers and their correlates in adults with type 1 or type 2 diabetes.MethodsIn this cross-sectional study, 3,383 Dutch adults with diabetes (42% type 1; 58% type 2) completed the 12-item ‘Adherence Starts with Knowledge’ questionnaire (ASK-12; total score range: 12-60) and reported socio-demographics, clinical and psychological characteristics and health behaviors. Univariable and multivariable logistic regression analyses were used.ResultsAdults with type 1 diabetes had a slightly lower mean ASK-12 score (i.e. more optimal medication intake and fewer perceived barriers) than adults with non-insulin-treated type 2 diabetes. After adjustment for covariates, correlates with suboptimal intake and barriers were fewer severe hypoglycemic events and more depressive symptoms and diabetes-specific distress. In type 2 diabetes, correlates were longer diabetes duration, more depressive symptoms and diabetes-specific distress.ConclusionsAdults with type 1 diabetes showed slightly more optimal medication intake and fewer perceived barriers than adults with non-insulin treated type 2 diabetes. Correlates differed only slightly between diabetes types. The strong association with depressive symptoms and diabetes-specific distress in both diabetes types warrants attention, as improving these outcomes in some people with diabetes might indirectly improve medication intake.
Comparative Study of NAP-XPS and Cryo-XPS for the Investigation of Surface Chemistry of the Bacterial Cell-Envelope
Authors: Kjærvik Marit , Ramstedt Madeleine , Schwibbert Karin , Dietrich Paul M. , Unger Wolfgang E. S. 
Published: April 2021

Bacteria generally interact with the environment via processes involving their cell-envelope. Thus, techniques that may shed light on their surface chemistry are attractive tools for providing an understanding of bacterial interactions. One of these tools is Al Kα-excited photoelectron spectroscopy (XPS) with its estimated information depth of &lt;10 nm. XPS-analyses of bacteria have been performed for several decades on freeze-dried specimens in order to be compatible with the vacuum in the analysis chamber of the spectrometer. A limitation of these studies has been that the freeze-drying method may collapse cell structure as well as introduce surface contaminants. However, recent developments in XPS allow for analysis of biological samples at near ambient pressure (NAP-XPS) or as frozen hydrated specimens (cryo-XPS) in vacuum. In this work, we have analyzed bacterial samples from a reference strain of the Gram-negative bacterium Pseudomonas fluorescens using both techniques. We compare the results obtained and, in general, observe good agreement between the two techniques. Furthermore, we discuss advantages and disadvantages with the two analysis approaches and the output data they provide. XPS reference data from the bacterial strain are provided, and we propose that planktonic cells of this strain (DSM 50090) are used as a reference material for surface chemical analysis of bacterial systems.
Stakeholder Perceptions on the Governance of Fisheries Systems Transformed by Hydroelectric Dam Development in the Madeira River, Brazil
Authors: Doria Carolina R. C. , Dutka-Gianelli Jynessa , Paes de Souza Mariluce , Lorenzen Kai , Athayde Simone 
Published: April 2021

Hydroelectric dams often have significant impacts on freshwater fisheries. Major impacts are known to be driven by changes in river hydrology and fish ecology, but the role of governance arrangements in mitigating or exacerbating fisheries impacts from hydropower development is less understood. This study presents an analysis of stakeholder perceptions about the effects of hydroelectric dam implementation on fisheries governance arrangements in the Madeira River basin, Brazil. Semi-structured interviews were conducted with 50 stakeholders representing the fishers and fish traders, government, non-governmental organizations, and the private sector. Fishers, non-governmental, and private sector agents perceived hydropower development to be the strongest factor driving fisheries decline or change over the past 10 years, while government staff perceived overfishing to be an equally or even more important factor. Most stakeholders affirmed that fisheries governance arrangements have weakened in the face of hydropower development, and that these arrangements have been insufficient to effectively mitigate or compensate for negative impacts on fisheries. Fishers, non-governmental and private sector agents saw lack of opportunities to participate in fisheries governance as a major contributing factor, while government staff emphasized lack of qualified personnel, lack of trust between agencies, and control over the decision-making process held by hydropower companies. Perspectives on other implications of governance arrangements were shared across stakeholder groups. These included increased conflicts; lack of interaction and coordination between agencies; the fragility of fishers’ social organization; lack of trust and reciprocity between organizations; and power imbalances between stakeholders. The results show that hydropower development impairs and changes relationships between diverse players involved in fisheries governance, which can exacerbate existing weaknesses and negatively affect fishery sustainability. Drawing from the perspectives and comments of the various stakeholders who participated in the study, we provide recommendations to improve freshwater fisheries governance in the Madeira River basin and in the Brazilian Amazon.
Treatment With Vasopressor Agents for Cardiovascular Shock Patients With Poor Renal Function; Results From the Japanese Circulation Society Cardiovascular Shock Registry
Authors: Yagi Tsukasa , Nagao Ken , Tachibana Eizo , Yonemoto Naohiro , Sakamoto Kazuo , Ueki Yasushi , Imamura Hiroshi , Miyamoto Takamichi , Takahashi Hiroshi , Hanada Hiroyuki , Chiba Nobutaka , Tani Shigemasa , Matsumoto Naoya , Okumura Yasuo 
Published: May 2021

According to the guidelines for cardiogenic shock, norepinephrine is associated with fewer arrhythmias than dopamine and may be the better first-line vasopressor agent. This study aimed to evaluate the utility of norepinephrine vs. dopamine as first-line vasopressor agent for cardiovascular shock depending on the presence and severity of renal dysfunction at hospitalization. This was a secondary analysis of the prospective, multicenter Japanese Circulation Society Cardiovascular Shock Registry (JCS Shock Registry) conducted between 2012 and 2014, which included patients with shock complicating emergency cardiovascular disease at hospital arrival. The analysis included 240 adult patients treated with norepinephrine alone (n = 98) or dopamine alone (n = 142) as the first-line vasopressor agent. Primary endpoint was mortality at 30 days after hospital arrival. The two groups had similar baseline characteristics, including estimated glomerular filtration rate (eGFR), and similar 30-day mortality rates. The analysis of the relationship between 30-day mortality rate after hospital arrival and vasopressor agent used in patients categorized according to the eGFR-based chronic kidney disease classification revealed that norepinephrine as the first-line vasopressor agent might be associated with better prognosis of cardiovascular shock in patients with mildly compromised renal function at admission (0.0 vs. 22.6%; P = 0.010) and that dopamine as the first-line vasopressor agent might be beneficial for cardiovascular shock in patients with severely compromised renal function [odds ratio; 0.22 (95% confidence interval 0.05–0.88; P = 0.032)]. Choice of first-line vasopressor agent should be based on renal function at hospital arrival for patients in cardiovascular shock.Clinical Trial Registration:http://www.umin.ac.jp/ctr/, Unique identifier: 000008441.