bluuebunny/crossref_metadata_2025_split huggingface dataset:
Accessing future crop yield and crop water productivity over the Heihe River basin in northwest China under a changing climate
Authors: Liu Qi , Niu Jun , Sivakumar Bellie , Ding Risheng , Li Sien 
Published: January 2021

AbstractQuantitative evaluation of the response of crop yield and crop water productivity (CWP) to future climate change is important to prevent or mitigate the adverse effects of climate change. This study made such an evaluation for the agricultural land over the Heihe River basin in northwest China. The ability of 31 climate models for simulating the precipitation, maximum temperature, and minimum temperature was evaluated for the studied area, and a multi-model ensemble was employed. Using the previously well-established Soil and Water Assessment Tool (SWAT), crop yield and crop water productivity of four major crops (corn, wheat, barley, and spring canola-Polish) in the Heihe River basin were simulated for three future time periods (2025–2049, 2050–2074, and 2075–2099) under two Representative Concentration Pathways (RCP4.5 and RCP8.5). The results revealed that the impacts of future climate change on crop yield and CWP of wheat, barley, and canola would all be negative, whereas the impact on corn in the eastern part of the middle reaches of the Heihe River basin would be positive. On the whole, climate change under RCP8.5 scenario would be more harmful to crops, while the corn crops in the Minle and Shandan counties have better ability to cope with climate change.
Depth variation of seismic moment and recurrence interval in Japan
Authors: Ji Yingfeng , Yoshioka Shoichi 
Published: January 2021

AbstractIn repeating seismic event sequences within a specialized horizontal area, the moment magnitude is usually scaled with the recurrence interval. In addition to two horizontal dimensions, the vertical dimension plays a certain role in affecting the scaling law. However, whether and how the changing depth influences the scaling law remain enigmatic. Based on a large number of earthquake records with high-resolution epicenter locations in recent decades in Japan, we focus on a comparison between the 3-D seismic moment and seismic interval, which recognize the vertical dimension as the same dimension as the horizontal distances. The results show that (1) the seismic moment scaling law is applicable in the multiparameter 3-D models by visiting the 1.8 million events collected during a period of 15 years; (2) the vertical dimension of depth plays an important role in the Mo–SI relationship as well as in the variance in the 3-D seismic moment–interval magnitudes; and (3) the seismic moment rate, attributable to the plate convergence rate, varies with area and depth in influencing the regional earthquake recurrence frequency.
Nationwide urban ground deformation monitoring in Japan using Sentinel-1 LiCSAR products and LiCSBAS
Authors: Morishita Yu 
Published: January 2021

AbstractGround subsidence in urban areas is a significant problem because it increases flood risk, damages buildings and infrastructure, and results in economic loss. Continual monitoring of ground deformation is important for early detection, mechanism understanding, countermeasure implementation, and deformation prediction. The Sentinel-1 satellite constellation has globally and freely provided frequent and abundant SAR data and enabled nationwide deformation monitoring through InSAR time series analysis. LiCSAR, an automatic Sentinel-1 interferometric processing system, has produced abundant interferograms with global coverage, and the products are freely accessible and downloadable through a web portal. LiCSBAS, an open source InSAR time series analysis package integrated with LiCSAR, enables users to obtain the deformation time series easily and quickly. In this study, spatially and temporally detailed deformation time series and velocities from the LiCSAR products using LiCSBAS for 73 major urban areas in Japan during 2014–2020 were derived. All LiCSBAS processing was automatically performed using predefined parameters. Many deformation signals with various temporal and spatial features, such as linear subsidence in Hirosaki, Kujyukuri, Niigata, and Kanazawa, episodic subsidence in Sanjo, annual vertical fluctuation in Hirosaki, Yamagata, Yonezawa, Ojiya, and Nogi, and linear uplift in Chofu were detected. Unknown small nonlinear uplift signals were found in Nara and Osaka in 2018. Complex postseismic deformations from the 2016 Kumamoto earthquake were also revealed. All the deformation data obtained in this study are available on an open repository and are expected to be used for further research, investigation, or interpretation. This nationwide monitoring approach using the LiCSAR products and LiCSBAS is easy to implement and applicable to other areas worldwide.
Development and feasibility of randomized trial to reduce urinary bisphenols in women with obesity
Authors: Hagobian Todd , Delli-Bovi Zoe , Mercado Adrian , Bird Alyssa , Guy Megan , Phelan Suzanne 
Published: January 2021

Abstract
Background
Bisphenol exposure is widespread and correlated with diabetes and cardiovascular disease. Previous intervention studies have successfully lowered bisphenol exposure among women of normal weight. The primary objective of this study was to develop and test the feasibility of a 3-week behavioral change intervention, rooted in social cognitive theory, to lower a broad range of bisphenols (BPA, BPS, and BPF) in women with obesity.

Methods
Thirty women with obesity (31.1 ± 5.6 kg/m2, 21.1 ± 3.1 years) were randomly assigned to an intervention or control. The intervention included weekly face-to-face meetings to reduce bisphenol exposures from food, cosmetics, and packaged products. Fasting urinary bisphenols, creatinine, and weight were assessed at study entry and after 3 weeks.

Results
The intervention was evaluated as feasible (100% of enrollment and recruitment, 96% of retention and attendance at lesson plan visits, and 96% of a collection of urine samples). Adherence to the intervention was estimated based on completion of self-monitoring records; the number of daily records completed was 7.7 ± 1.3 (mean ± SD) after week 1, 7.1 ± 1.5 after week 2, and 4.4 ± 0.9 after week 3. In secondary analysis, there was a significant treatment × time effect on creatinine-corrected urinary BPS (− 1.42 μg/g creatinine in the intervention vs. − 0.09 μg/g creatinine in the control group).

Conclusion
In women with obesity, the 3-week intervention was considered feasible with promising preliminary results of decreasing BPS concentrations. These data warrant future large-scale clinical trial interventions to reduce bisphenol exposure and determine whether reductions in bisphenols positively impact diabetes and cardiovascular disease risk markers. This study was retroactively registered at ClinicalTrial.gov Identifier NCT03440307.
Agricultural adaptation to climate change in the trans-Himalaya: a study of Loba Community of Lo-manthang, Upper Mustang, Nepal
Authors: Khattri Man Bahadur , Pandey Rishikesh 
Published: January 2021

AbstractThis paper presents community interference on agricultural ecology against climate change impacts in Lo-manthang, Upper-Mustang, Nepal. The peoples’ response strategies are based on traditional agroecological knowledge. This study applied the human ecological approach (Cause ➔ Effect ➔ Response) to analyze continuity and change in the agricultural practice of the indigenousLobacommunity of the Trans-Himalaya. Data were generated through anthropological fieldwork using quasi-ethnomethodology. Qualitative data on changing climate was further supported by the analysis of meteorological records of last 40 years from the nearest station. The overall impression of the study is that theLobasare hardly adapting to the dynamics of socio-environmental factors as climatic, geo-environmental, and politico-institutional changes. The strategy adopted to respond to the impacts of change on the local livelihoods is particularly associated with altering traditional agricultural practices. Indigenous knowledge-based systems of farm, labor, and resource management, accompanied by changes in food preference (food value) and linking agriculture with spiritual practice, are specific adaptation options, further supported by emerging options such as occupational modernization and migration. However, not all of these strategies produced positive outcomes in the local socio-ecological system of Lo-manthang. Therefore, policymakers should recognize Trans-Himalayan environmental uniqueness and its sensitivity to different drivers while designing policy to address them.
Ecological risk assessment of the levels of polycyclic aromatic hydrocarbons in soils of the abandoned sections of Orji Mechanic Village, Owerri, Imo State, Nigeria
Authors: Ibe Francis Chizoruo , Duru Chidi Edbert , Isiuku Benaiah Obinna , Akalazu Jacienta Ngozi 
Published: January 2021

Abstract
Background
Ecological risk assessment of the levels of polycyclic aromatic hydrocarbons in soils of the abandoned sections of Orji Mechanic Village, Owerri, Imo State, Nigeria. The main objective of the study was to determine the levels of soil contamination from polycyclic aromatic compounds (PAHs) due to anthropogenic events in the mechanic village before reclamation.

Results
Analysis of soil samples revealed mean PAH levels ranging from 1.22E−02 ± 0.00 to 5.60E−02 ± 0.01 mg/kg, with higher PAH concentrations observed at 0–10 cm compared to other depths. The sum of PAHs (∑PAHs) ranged from 1.58E−01 to 6.71E−01 mg/kg, as the sum of low molecular weight PAHs (∑LPAHs) varied from 7.16E−03 to 1–1.60E−01 mg/kg, while the sum of high molecular weight PAHs (∑HPAHs) ranged from 1.81E−02 to 5.42E−01 mg/kg. The sum of carcinogenic PAHs (∑Carcino-PAHs) varied from 5.39E−01 to 9.74E−02 mg/kg, indicating elevated levels of carcinogens in the sampled soils. Diagnostic ratio, principal component, and correlation analysis of the results revealed that pyrogenic sources were primarily responsible for the observed PAHs owing to the activities of automobile mechanics in the Orji Mechanic Village. Benzo(a)pyrene equivalent (BePeq) of the PAHs indicated high carcinogenic potency for sample A. The total cancer risk was above 1 × 10–6, indicating a greater risk of cancer due to contact with the contaminated soil samples; hence, the result of this study is a serious ecological concern.

Conclusion
There may be accumulation of these contaminants in the investigated area, which will eventually contaminate the groundwater as well as surface water resources. Remedial measures to prevent possible health problems due to the PAHs which results from the activities of automobile mechanics are therefore recommended.
Long-term result of a second or third two-stage revision total knee arthroplasty for infected total knee arthroplasty
Authors: Kim Young-Hoo , Park Jang-Won , Jang Young-Soo 
Published: January 2021

AbstractBackgroundPersistent or recurrent infection after two-stage revision total knee arthroplasty (TKA) for the treatment of an infected TKA is a dreaded complication. The purpose of the current study was to determine the ability of a second or third two-stage revision TKA to control infection, evaluate the long-term survivorship of the TKA prosthesis, and measure the functional outcome after a second or third two-stage revision TKA for reinfection.MethodsWe evaluated 63 patients (65 knees) with failed two-stage TKA treated with a second or a third two-stage revision TKA. There were 25 men and 38 women (mean age, 67 ± 10.2 years). The mean follow-up from the time of a second two-stage TKA revision was 15.1 years (range, 10 to 19 years) and the mean follow-up from the time of a third two-stage TKA revision was 7 years (range, 5 to 10 years).ResultsOverall, infection was successfully controlled in 49 (78%) of 65 knees after a second two-stage revision TKA was performed. In the remaining 16 knees, recurrent infection was successfully controlled in 12 knees (75%) after a third two-stage revision TKA. Survivorship, free of implant removal for recurrent infection, was 94% at 15.1 years (95% CI, 91 to 100%). Survival free of revision TKA for mechanical failure was 95% (95% CI, 92 to 100%).ConclusionsThe results of the current study suggest that a second or a third two-stage revision TKA is a reasonable option for controlling infection, relieving pain, and achieving a satisfactory level of function for patients with infected TKAs.
How perceived organizational politics cause work-to-family conflict? Scoping and systematic review of literature
Authors: Fiaz Sumbol , Qureshi Muhammad Azeem 
Published: January 2021

AbstractWork–family conflict is a subject of interest for researchers in the field of organizational behavior for decades because of its negative impact on an individual’s life. The existing literature identified that workplace stressors contribute to work–family conflict and Perceived Organizational Politics emerged as an aversive workplace stressor. From empirical pieces of evidence, it is observed that perceived organizational politics and work–family conflict are indirectly associated with each other, and their impact on employees is unavoidable. To explore this uncovered relationship, at first, this study used a keywords co-occurrence network mapping approach and found that perceived organizational politics and work–family conflict are associated with each through various workplace variables. Further, with the help of a scoping review identify those specific variables, and, lastly, a systematic review approach used to identify a mechanism of how these identified variables form an association between perceived organizational politics and work–family conflict. Based on the findings of the systematic review, this study proposed a conceptual framework that extends the existing literature by providing new insight into concepts of perceived organizational politics by linking it with work–family conflict. This study introduced a novel way to develop a conceptual framework by linking three distinct approaches of research. In the last, this study proposed recommendations for future research.
Acute kidney injury in hospitalized patients with COVID-19 (retrospective study)
Authors: Azeem Haitham A. , Abdallah Hytham , Abdelnaser Mohamad M. 
Published: January 2021

Abstract
Background
The World Health Organization (WHO) has named the virus as 2019 novel coronavirus on January 12, 2020, and has declared a public health emergency globally on January 30, 2020. The epidemic started in Wuhan, China, in December of 2019 and quickly spread to over 200 countries. COVID-19 can cause multiple organ injuries (e.g., kidney, heart, blood, and nervous system). Among them, acute kidney injury (AKI) is a critical complication due to its high incidence and mortality rate. So, it is essential to evaluate AKI in COVID-19 patients during this pandemic state. The aim of this work is to detect the occurrence of AKI in hospitalized COVID-19 patients. So, a retrospective study was conducted on hospitalized adult patients > 18 years old with confirmed SARS-CoV-2 infection admitted to the Abo Teeg Hospital at Assiut City, Egypt, from May 1, 2020, to July 1, 2020. All data were collected from medical records, patients’ follow-up, and charts. Data were verified, coded by the researcher, and analyzed using IBM-SPSS 21.0.

Results
Eighty-six COVID-19 patients were admitted to Abo Teeg Hospital in Assiut City, Egypt, between May and July 2020. Thirty-eight patients (33%) were of the male gender. Mean age was 58.07 ± 17.9, and 61 patients developed AKI. 32.8% of the AKI group were a stage I severity (increase in serum creatinine by 0.3 mg/dl within 48 h), 21.3% of them presented by stage II (2–2.9 times increase in serum creatinine), and 45.9% were in stage III (3 times or more increase in serum creatinine). The overall hospital mortality for the patients admitted to ICU with AKI was 6.7% (11/61), compared to 1% (4/25) in those without AKI.

Conclusion
Hospitalized patients with COVID-19 had a higher risk of AKI, and we recommended that those patients should be evaluated after discharge for the development of CKD.
Chronic Lymphocytic Leukemia: Prognostic Factors at Presentation in a Resource-Limited Center
Authors: Korubo Kaladada Ibitrokoemi , Okite Uchechukwu Prince , Ezeugwu Sampson Ibekwe 
Published: January 2021

PURPOSE Determining chronic lymphocytic leukemia (CLL) prognosis using the International Prognostic Index markers such as TP53 and immunoglobulin heavy-chain variable region gene mutation in a resource-limited setting is difficult to achieve because of cost and equipment unavailability. The aim of this study is to determine prognostic factors easily available to hematologists in low- or medium-income countries. MATERIALS AND METHODS This was a retrospective study conducted at the University of Port Harcourt Teaching Hospital, Nigeria. Data were retrieved from CLL patient records from January 2004 to December 2019 (15 years). Data collected were analyzed using SPSS software version 25. RESULTS A total of 46 records were reviewed, with a median age of 55 years and a male:female ratio of 1:1.2. All patients were symptomatic at presentation, with splenomegaly (91.3%), anemia (82.6%), and lymphadenopathy (76.1%) predominating. About 89.1% of the patients presented at Binet stage C and/or high-risk Rai (Rai stages III and IV) with 10.9% presenting at Binet stage B and/or intermediate-risk Rai (Rai stage II). Only 13% of the patients had immunophenotyping done with 6.5% being done for the Matutes CLL score. The 5-year overall survival (OS) was 15.7% with a median survival of 26 months. WBC count and absolute lymphocyte count (ALC) > 100 × 109/L were significant poor prognostic markers ( P = .013 and .021, respectively). Thirty-five (76.1%) received chemotherapy, and they had a better median survival than those who did not (26 v 17.5 months). The most common regimen used was cyclophosphamide, vincristine, and prednisolone for 15 (42.9%) patients. CONCLUSION WBC count and ALC > 100 × 109/L were poor prognostic markers. Patients who received chemotherapy had a better OS.
Socioeconomic Factors Influence the Impact of Tumor HPV Status on Outcome of Patients With Oropharyngeal Squamous Cell Carcinoma
Authors: Marks Jennifer A. , Switchenko Jeffrey M. , Steuer Conor E. , Ryan Martha , Patel Mihir R. , McDonald Mark W. , Higgins Kristin , Beitler Johnathan J. , Shin Dong M. , Gillespie Theresa W. , Saba Nabil F. 
Published: January 2021

PURPOSE: Human papilloma virus (HPV) association remains one of the most important predictors of clinical outcome in oropharyngeal squamous cell carcinoma (OPSCC). We aimed to determine whether the relationship between HPV status and overall survival was influenced by socioeconomic factors. MATERIALS AND METHODS: Using the National Cancer Database, we examined the relationship between socioeconomic status and overall survival, controlling for demographics and socioeconomic variables (age at diagnosis, race, sex, clinical stage, facility type, facility location, insurance status, median-income quartiles, percent of no high-school education quartiles, rural-urban dwelling, Charlson-Deyo score, primary site, and treatment type). RESULTS: HPV-positive patients with private insurance have improved overall survival compared with HPV-positive patients who are uninsured (hazard ratio [HR], 0.51, 95% CI, 0.41 to 0.63, P < .001). HPV-negative patients with private insurance have improved overall survival compared with HPV-negative patients who were uninsured (HR, 0.62, 95% CI, 0.53 to 0.73, P < .001). HPV-positive patients living in the south had improved overall survival compared with HPV-positive patients living in the west (HR, 0.83, 95% CI, 0.72 to 0.96, P = .013). As assessed through interaction, relationships between survival and insurance ( P = .004), rural-urban status ( P = .009), and facility location ( P = .021) statistically differed between HPV-positive and HPV-negative patients. CONCLUSION: HPV status impact on overall survival for patients with OPSCC is influenced by socioeconomic factors including insurance status and treatment facility. A deeper understanding of these interactions is needed to improve equity of care for patients with OPSCC.
Circulating Tumor DNA Predicts Pathologic and Clinical Outcomes Following Neoadjuvant Chemoradiation and Surgery for Patients With Locally Advanced Rectal Cancer
Authors: McDuff Susan G. R. , Hardiman Karin M. , Ulintz Peter J. , Parikh Aparna R. , Zheng Hui , Kim Daniel W. , Lennerz Jochen K. , Hazar-Rethinam Mehlika , Van Seventer Emily E. , Fetter Isobel J. , Nadres Brandon , Eyler Christine E. , Ryan David P. , Weekes Colin D. , Clark Jeffrey W. , Cusack James C. , Goyal Lipika , Zhu Andrew X. , Wo Jennifer Y. , Blaszkowsky Lawrence S. , Allen Jill , Corcoran Ryan B. , Hong Theodore S. 
Published: January 2021

PURPOSE This study was designed to assess the ability of perioperative circulating tumor DNA (ctDNA) to predict surgical outcome and recurrence following neoadjuvant chemoradiation for locally advanced rectal cancer (LARC). MATERIALS AND METHODS Twenty-nine patients with newly diagnosed LARC treated between January 2014 and February 2018 were enrolled. Patients received long-course neoadjuvant chemoradiation prior to surgery. Plasma ctDNA was collected at baseline, preoperatively, and postoperatively. Next-generation sequencing was used to identify mutations in the primary tumor, and mutation-specific droplet digital polymerase chain reaction was used to assess mutation fraction in ctDNA. RESULTS The median age was 54 years. The overall margin-negative, node-negative resection rate was 73% and was significantly higher among patients with undetectable preoperative ctDNA (n = 17, 88%) versus patients with detectable preoperative ctDNA (n = 9, 44%; P = .028). Undetectable ctDNA was also associated with more favorable neoadjuvant rectal scores (univariate linear regression, P = .029). Recurrence-free survival (RFS) was calculated for the subset (n = 19) who both underwent surgery and had postoperative ctDNA available. At a median follow-up of 20 months, patients with detectable postoperative ctDNA experienced poorer RFS (hazard ratio, 11.56; P = .007). All patients (4 of 4) with detectable postoperative ctDNA recurred (positive predictive value = 100%), whereas only 2 of 15 patients with undetectable ctDNA recurred (negative predictive value = 87%). CONCLUSION Among patients treated with neoadjuvant chemoradiation for LARC, patients with undetectable preoperative ctDNA were more likely to have a favorable surgical outcome as measured by the rate of margin-negative, node-negative resections and neoadjuvant rectal score. Furthermore, we have confirmed prior reports indicating that detectable postoperative ctDNA is associated with worse RFS. Future prospective study is needed to assess the potential for ctDNA to assist with personalizing treatment for LARC.