bluuebunny/crossref_metadata_2025_split huggingface dataset:
Creation and Validation of a Novel Sex‐Specific Mortality Risk Score in LVAD Recipients
Authors: Nayak Aditi , Hu Yingtian , Ko Yi‐An , Steinberg Rebecca , Das Subrat , Mehta Anurag , Liu Chang , Pennington John , Xie Rongbing , Kirklin James K. , Kormos Robert L. , Cowger Jennifer , Simon Marc A. , Morris Alanna A. 
Published: March 2021

Background
Prior studies have shown that women have worse 3‐month survival after receiving a left ventricular assist device compared with men. Currently used prognostic scores, including the Heartmate II Risk Score, do not account for the increased residual risk in women. We used the IMACS (International Society for Heart and Lung Transplantation Mechanically Assisted Circulatory Support) registry to create and validate a sex‐specific risk score for early mortality in left ventricular assist device recipients.

Methods and Results

Adult patients with a continuous‐flow LVAD from the IMACS registry were randomly divided into a derivation cohort (DC; n=9113; 21% female) and a validation cohort (VC; n=6074; 21% female). The IMACS Risk Score was developed in the DC to predict 3‐month mortality, from preoperative candidate predictors selected using the Akaike information criterion, or significant sex × variable interaction. In the DC, age, cardiogenic shock at implantation, body mass index, blood urea nitrogen, bilirubin, hemoglobin, albumin, platelet count, left ventricular end‐diastolic diameter, tricuspid regurgitation, dialysis, and major infection before implantation were retained as significant predictors of 3‐month mortality. There was significant ischemic heart failure × sex and platelet count × sex interaction. For each quartile increase in IMACS risk score, men (odds ratio [OR], 1.86; 95% CI, 1.74–2.00;
P
<0.0001), and women (OR, 1.93; 95% CI, 1.47–2.59;
P
<0.0001) had higher odds of 3‐month mortality. The IMACS risk score represented a significant improvement over Heartmate II Risk Score (IMACS risk score area under the receiver operating characteristic curve: men: DC, 0.71; 95% CI, 0.69–0.73; VC, 0.69; 95% CI, 0.66–0.72; women: DC, 0.73; 95% CI, 0.70–0.77; VC, 0.71 [95% CI, 0.66–0.76;
P
<0.01 for improvement in receiver operating characteristic) and provided excellent risk calibration in both sexes. Removal of sex‐specific interaction terms resulted in significant loss of model fit.

Conclusions
A sex‐specific risk score provides excellent risk prediction in LVAD recipients.
Do male Boana goiana (Lutz, 1968) (Anura: Hylidae) discriminate between the calls of neighbours and strangers?
Authors: Morais Alessandro R. , Siqueira Mariana N. , Márquez Rafael , Bastos Rogério P. 
Published: March 2021

Abstract
Neighbour-stranger discrimination is an important mechanism in social behaviour, as it allows the individual to avoid the high energetic costs of repeated agonistic interactions with neighbours. In some anuran species, the owners of territories respond more aggressively towards strangers than neighbours. Here, we investigated whether gladiator frog, Boana goiana, males discriminate between neighbours and strangers. This is a lek-breeding species; therefore, it does not defend fixed territories which are associated with a specific resource. We conducted a playback field experiment with a repeated-measures design, based on three treatments: (i) neighbour’s call in initial position, (ii) stranger’s call in initial position, and (iii) neighbour’s call in new position. We did not observe any systematic modification in the acoustic properties (call duration, dominant frequency, repetition rate) of the advertisement and short aggressive calls of B. goiana males given in response to our playback treatments. Our results indicate that B. goiana males do not exhibit vocally mediated ‘dear enemy’ relationships. We discuss the possible ecological and social factors that may have impeded the evolution of ‘dear enemy’ relationships in this species.
A Bumpy Ride: China’s Search to Be a Responsible Power
Authors: Jia Qingguo 
Published: March 2021

Summary
Recent years have seen China trying to play the role of a responsible power. It has made great efforts in this regard, including actively participating in international peacekeeping operations, collaborating with other countries to deal with the climate change and trying to help in fighting the COVID-19 pandemic. However, China’s efforts have met with stiff resistance from the West, especially from the Donald Trump-led United States. How does one explain this turn of events? This essay argues that the speed of China’s rise; the Western perception of China’s domestic development; the failure to address domestic problems on the part of some major Western countries, especially the United States; and the role that the Trump administration played provide important clues to such a development.
Missives from the Frontier (130-152/747-769): Al-Awzāʿī and the Abbasids
Authors: Mikati Rana 
Published: March 2021

Abstract
This article examines and proposes a chronology for the extant correspondence of the Syrian legal scholar al-Awzāʿī (d. 157/773-4), arguing that the majority of the letters belong to the Abbasid phase of the scholar’s career. The letters are then used to highlight the network in which al-Awzāʿī operated and the role he played for the frontier communities. Finally, these letters shed light on the conditions of life of the Syrian frontier communities and their interaction with the Abbasid authorities.
The Risk of Birth
Authors: Barker Hannah 
Published: March 2021

AbstractWhy did fifteenth-century Genoese slaveholders insure the lives of enslaved pregnant women? I argue that their assessment of the risks associated with childbirth reflected their views on the connection between slavery, property, and lineage. Genoese slaveholders saw the reproductive labor of enslaved women as a potential contribution to their lineage as well as their property. Because their children by enslaved women might become their heirs, Genoese slaveholders were inclined to worry about and seek protection against the risk of maternal mortality. In the context of the commercial revolution and the rise of third-party insurance, they developed life insurance for enslaved pregnant women to complement the fines already required of those who illegally impregnated enslaved women and thereby endangered their lives.
Streamflow simulation in data-scarce basins using Bayesian and physics-informed machine learning models
Authors: Lu Dan , Konapala Goutam , Painter Scott L. , Kao Shih-Chieh , Gangrade Sudershan 
Published: March 2021

AbstractHydrologic predictions at rural watersheds are important but also challenging due to data shortage. Long Short-TermMemory (LSTM) networks are a promising machine learning approach and have demonstrated good performance in streamflow predictions. However, due to its data-hungry nature, most of LSTM applications focused on well-monitored catchments with abundant and high quality observations. In this work, we investigate predictive capabilities of LSTM in poorly monitored watersheds with short observation records. To address three main challenges of LSTM applications in data-scarce locations, i.e., overfitting, uncertainty quantification (UQ), and out-of-distribution prediction, we evaluate different regularization techniques to prevent overfitting, apply a Bayesian LSTM for UQ, and introduce a physics-informed hybrid LSTM to enhance out-of-distribution prediction. Through case studies in two diverse sets of catchments with and without snow influence, we demonstrate that: (1) when hydrologic variability in the prediction period is similar to the calibration period, LSTM models can reasonably predict daily streamflow with Nash-Sutcliffe efficiency above 0.8, even with only two years of calibration data. (2) When the hydrologic variability in the prediction and calibration periods is dramatically different, LSTM alone does not predict well, but the hybrid model can improve the out-of-distribution prediction with acceptable generalization accuracy. (3) L2 norm penalty and dropout can mitigate overfitting, and Bayesian and hybrid LSTM have no overfitting. (4) Bayesian LSTM provides useful uncertainty information to improve prediction understanding and credibility. These insights have vital implications for streamflow simulation in watersheds where data quality and availability are a critical issue.
A Diurnal Predictability Barrier for Weather Forecasts
Authors: Wang Peng , Jin Yishuai , Liu Zhengyu 
Published: March 2021

AbstractIn this study, we investigate a diurnal predictability barrier (DPB) for weather predictions using an idealized model and observations. This DPB is referred to a maximum drop of predictability (e.g., autocorrelation) at a particular time of the day, regardless of the initial time. Previous studies demonstrated that a strong seasonal cycle of El Niño-Southern Oscillation (ENSO) growth rate is responsible for the seasonal predictability barrier of the ENSO in spring. This led us to investigate whether or not a strong diurnal cycle may generate a DPB. We study the DPB using an idealized model, the Lorenz 1963 model (Lorenz63), with the addition of a diurnal cycle. We find that diurnal growth rate can generate a DPB in this chaotic system, regardless of the initial error. Finally, by calculating the autocorrelation function using the hourly data of surface temperature, we explore the DPB at two stations in Wisconsin, USA and Beijing, China. A clear DPB feature is found at both stations. The dramatic drop of predictability at a specific time of the day is likely due to the diurnal variation of the system. This is a new feature that needs further study for short-term weather predictions.
Uncertainty in the “New Normal”: Understanding the Role of Climate Change Beliefs and Risk Perceptions in Michigan Tree Fruit Growers’ Adaptation Behaviors
Authors: Linder Julia , Campbell-Arvai Victoria 
Published: March 2021

AbstractIn the midwestern United States, intensifying impacts from climate change necessitate adaptation by the agricultural sector. Tree fruit agriculture is uniquely vulnerable to climate change due to the long-lived nature of perennial systems, yet very few studies have addressed how fruit growers perceive climate change and are responding to climate risks. For this study, 16 semistructured interviews were conducted with Michigan tree fruit growers to understand how their climate change beliefs, beliefs about adaptive actions, and climate-related risk perceptions influence adaptation behaviors. While there was a great deal of uncertainty about the anthropogenic nature of climate change, growers generally agreed that unprecedented changes in climate and weather patterns were occurring. Because of a perception of little control over future climate impacts, most growers reactively adapted to climate risks that negatively impacted their orchards by implementing measures such as frost protection, irrigation, pesticides, and crop insurance. This study highlighted that while proactive adaptations such as crop diversification, planting new varieties, and improving soil health will be necessary to increase farm resilience in the future, growers were unable to justify making these changes due to their uncertainty about future climate changes. The findings from this study highlight the need for future outreach efforts by university extension agents, private agricultural advisors, and federal and state agency advisors to provide educational information on the long-term impacts of climate change in order to help growers increase the resilience of their farm in the face of future climate impacts.
Participation in Community Gardening: Sowing the Seeds of Well-Being: Participation au jardinage communautaire : pour semer les graines du bien-être
Authors: Suto Melinda J. , Smith Shelagh , Damiano Natasha , Channe Shurli 
Published: March 2021

Background. Sustaining well-being challenges people with serious mental health issues. Community gardening is an occupation used to promote clients’ well-being, yet there is limited evidence to support this intervention. Purpose. This paper examines how facilitated community gardening programs changed the subjective well-being and social connectedness of people living with mental health issues. Method. A community-based participatory research approach and qualitative methods were used with 23 adults living in supported housing and participating in supported community gardening programs. A constructivist approach guided inductive data analysis. Findings. Participation in community gardening programs enhanced well-being through welcoming places, a sense of belonging, and developing positive feelings through doing. The connection to living things and responsibility for plants grounded participants in the present and offered a unique venue for learning about gardening and themselves. Implications. Practitioners and service-users should collaborate to develop leadership, programs, places, and processes within community gardens to enhance well-being.
Conflicting Goals Influence Physicians’ Expressed Beliefs to Patients and Colleagues
Authors: Yin Siyuan , Arkes Hal R. , McCoy John P. , Cohen Margot E. , Mellers Barbara A. 
Published: March 2021

Background Physicians who communicate their prognostic beliefs to patients must balance candor against other competing goals, such as preserving hope, acknowledging the uncertainty of medicine, or motivating patients to follow their treatment regimes. Objective To explore possible differences between the beliefs physicians report as their own and those they express to patients and colleagues. Design An online panel of 398 specialists in internal medicine who completed their medical degrees and practiced in the United States provided their estimated diagnostic accuracy and prognostic assessments for a randomly assigned case. In addition, they reported the diagnostic and prognostic assessments they would report to patients and colleagues more generally. Physicians answered questions about how and why their own beliefs differed from their expressed beliefs to patients and colleagues in the specific case and more generally in their practice. Results When discussing beliefs about prognoses to patients and colleagues, most physicians expressed beliefs that differed from their own beliefs. Physicians were more likely to express greater optimism when talking to patients about poor prognoses than good prognoses. Physicians were also more likely to express greater uncertainty to patients when prognoses were poor than when they were good. The most common reasons for the differences between physicians’ own beliefs and their expressed beliefs were preserving hope and acknowledging the inherent uncertainty of medicine. Conclusion To balance candor against other communicative goals, physicians tended to express beliefs that were more optimistic and contained greater uncertainty than the beliefs they said were their own, especially in discussions with patients whose prognoses were poor.
Multidisciplinary team management of 46,XY 17α-hydroxylase deficiency: a case report and literature review
Authors: Zhou Yang , Xue Xue , Shi Panpan , Lu Qinrui , Lv Shulan 
Published: March 2021

Background We report here a case study of 17α-hydroxylase deficiency in a phenotypic girl with male karyotype (46,XY). We also review the relevant literature to deepen our understanding of the disease, reduce the rate of missed diagnosis, and emphasize that holistic management of this disease requires collaborative multidisciplinary teamwork. Case presentation A 14-year-old patient with a female phenotype visited the endocrinology department because of hypertension. The patient had primary amenorrhea and lacked secondary sexual characteristics. Initial laboratory evaluation revealed normal levels of electrolytes, a hypergonadotropic hypogonadal state with high progesterone and low testosterone levels, and a 46,XY karyotype. She was referred to the urology department for gonadectomy and transferred to the gynecological endocrine clinic. On the basis of the patient’s medical history and genetic testing results, a diagnosis of 46,XY 17α-hydroxylase deficiency was made. The patient was provided with glucocorticoids, estrogens, metformin, and psychological support. Conclusions Patients with 17α-hydroxylase deficiency, a rare cause of congenital adrenal hyperplasia, should be treated by a multidisciplinary team. Relevant experts from different disciplines should set up a systematic and comprehensive individualized management plan to optimize the physical and mental health and quality of life of affected patients.
“I never heard anything about it”: Knowledge and psychosocial needs of Latina breast cancer survivors with lymphedema
Authors: Buki Lydia P , Rivera-Ramos Zully A , Kanagui-Muñoz Marlen , Heppner Puncky P , Ojeda Lizette , Lehardy Emaan N , Weiterschan Kari A 
Published: March 2021

Objective: Breast cancer is the most commonly diagnosed form of cancer and the leading cause of cancer-related death among Latina women in the United States. One aspect of recovery that has been underrepresented in the English-language literature is the recovery of Latina women who have developed lymphedema, a debilitating condition characterized by persistent swelling of the arm, hand, chest, and/or breast. To fill this research gap, a study was conducted to examine the lived experiences of Latina women with breast cancer-related lymphedema. Methods: Given the limited scholarship on this topic, qualitative methods were used to obtain a foundational and nuanced understanding of Latina women’s experiences. Semi-structured interviews were conducted with a sample of 10 Latina survivors with breast cancer-related lymphedema. Data were analyzed through thematic analysis and constant comparison methodology. Results: The data analysis yielded three major themes: knowledge of lymphedema, impact of lymphedema diagnosis, and coping with lymphedema. Participants had limited knowledge of lymphedema and its risk factors upon diagnosis, in addition to barriers accessing quality care. They also noted psychological distress related to a significant financial burden as well as social anxiety related to interacting with others while wearing compression gloves or sleeves. A major coping strategy was receiving social support from friends, family, peers in structured support groups, and spiritual/religious groups or practices. Conclusions: Our findings bring to light contextual factors that may place Latina breast cancer survivors at increased risk for lymphedema and for experiencing a high burden managing their condition. Recommendations are provided for primary, secondary, and tertiary prevention.
The Area of Impingement in the Throwing Versus Nonthrowing Shoulder of Collegiate Baseball Players: An MRI Study of the Simulated Late-Cocking Phase of Throwing
Authors: Takahashi Makoto , Iwamoto Koji , Monma Masahiko , Mutsuzaki Hirotaka , Mizukami Masafumi 
Published: March 2021

Background: During shoulder abduction and external rotation, internal impingement can occur when compressive forces between the greater tuberosity and the posterior glenoid rim pinch the undersurface of the rotator cuff. Previous studies on internal impingement have focused on qualitative results such as pathological findings; however, few studies have quantified the area of impingement (AOI) of the rotator cuff muscles between the greater tuberosity and the posterior glenoid rim. Purpose: To compare the AOI between the throwing and nonthrowing shoulders of baseball players. Study Design: Controlled laboratory study. Methods: A total of 14 asymptomatic male collegiate baseball players participated in this study. The AOI in both the throwing and the nonthrowing shoulders was calculated using magnetic resonance imaging (MRI) scans. The MRI measurements were collected with the shoulder at 90° of abduction and at 90° and 100° of external rotation. The area, width, and depth of impingement as well as cystic changes in the greater tuberosity and degeneration in the posterior labrum were compared between the throwing and nonthrowing shoulders. Results: The AOI was significantly greater in the throwing shoulders than in the nonthrowing shoulders (90° of external rotation: 32.4 vs 19.1 mm2, respectively; 100° of external rotation, 28.0 vs 15.6 mm2, respectively; P < .001 for both). Compared with the nonthrowing shoulders, there were more positive findings in the throwing shoulders regarding greater tuberosity cystic changes (0 vs 7, respectively; P = .006) and posterior labral degeneration (3 vs 13, respectively; P < .001). Conclusion: The AOI and the number of lesions in the greater tuberosity and posterior labrum were greater in throwing shoulders than in nonthrowing shoulders. Therefore, damage to the insertion of the rotator cuff muscles may affect internal impingement. Clinical Relevance: Lesions in the greater tuberosity and posterior labrum in throwing shoulders may increase the AOI by expanding the joint gap behind the glenohumeral joint. Impingement of the greater tuberosity and the posterior glenoid rim may lead to rotator cuff tears.
The effect of oil heat treatment on biological, mechanical and physical properties of bamboo
Authors: Hao Xiaomeng , Wang Qiuyi , Wang Yihua , Han Xin , Yuan Chenglong , Cao Yu , Lou Zhichao , Li Yanjun 
Published: March 2021

AbstractBamboo is now widely used in construction, papermaking, textile, furniture and other fields because of its renewable, fast-growing, high-strength, high-yield and easy processing. However, compared with wood, bamboo and bamboo products are more vulnerable to damage by fungi and pests. An effective and eco-friendly method is urgently needed to improve their physical and chemical properties, decay resistance and anti-mildew properties, and hydrophobic properties. Here, bamboo was heated with methyl silicone oil. The effect of different temperatures (140 °C–200 °C) and different times (2 h–6 h) on the properties of bamboo was studied systematically, including chemical composition, physical and mechanical properties, surface wettability, decay resistance and anti-mildew property. No starch granules were observed inside the parenchymal cell lumen of bamboo specimen heat treated at 200 °C for 6 h. And with the increase of heat treatment temperature and time, the content of cellulose and hemicellulose decreases gradually while relative content of lignin increases due to its better thermal stability. Accordingly, the surface wettability decreases due to the changes of the surface functional groups and micro-morphologies. Under the condition of oil heat treatment at 160 °C for 2 h, the compressive strength parallel to grain of bamboo samples reach the maximum of 109.52 MPa. With further increase of heating temperature, the corresponding compressive strength decreases. The resulted bending strength and MOE both display similar changing trend. However, the optimal parameter is at 180 °C for 2 h, with the highest bending strength and MOE values of 142.42 MPa and 12,373.00 MPa, respectively. Finally, the decay resistance and anti-mildew property are dramatically enhanced with increased heat treatment temperature and time. All the corresponding changing mechanisms are investigated in depth and in detail. Our results provide comprehensive process parameters and micro-mechanism for the performance of oil heat treatment of bamboo, which can be used to guide the actual production.