bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Positive Relationship Between Caffeine Intake and Endometriosis: A Cross‐Sectional Study of the National Health and Nutrition Examination Survey 1999–2006
Authors: Qin Rongyan , Yang Yuni , Xie Baoli , Huang Yingqing , Guo Yuying , Li Yanhui , Yu Jiaxin , Liao Ming , Qin Aiping 
Published: December 2024

ABSTRACTBackgroundCaffeine has been suggested to have a relationship with endometriosis as a widely consumed psychoactive substance, although findings are inconsistent.ObjectiveThis study explored the potential associations and threshold effects between caffeine intake and endometriosis using cross‐sectional data from the National Health and Nutrition Examination Survey (NHANES) from 1999 to 2006.MethodsThe study included 248 women with endometriosis and 2944 without, aged 20–50 years. Caffeine intake was assessed through a 24‐h dietary recall, and endometriosis was identified via self‐report. Logistic regression models were used to investigate the associations between caffeine intake and endometriosis, adjusting for age, race, body mass index, marital status, education, ever pregnant, smoke, drink, hypertension, hyperlipidemia, diabetes, energy, protein, total fat and dietary fibre. The restricted cubic spline (RCS) regression was employed to examine nonlinear relationships and threshold effects.ResultsThis study found a significant correlation between endometriosis and caffeine intake, with both high and low levels associated with the condition (OR 1.65, 95% CI: 1.12, 2.42, p = 0.011 for high; OR 1.60, 95% CI: 1.05, 2.44, p = 0.028 for low). Their relationship is still significant after adjustment for covariates. This suggests a complex dose–response relationship, confirmed by RCS regression, which revealed a U‐shaped curve. Endometriosis incidence was lowest at 170.25 mg/day caffeine intake.ConclusionThe research suggests that an optimal caffeine intake is 170.25 mg/day, with both higher and lower levels associated with endometriosis. We acknowledge that the cross‐sectional design limits causal inference and that reliance on self‐reported data may introduce bias. Nevertheless, our findings lay the groundwork for future investigations into the dose–response relationship between caffeine intake and endometriosis.
Oil discovery, energy transition, and the decline in wholesale prices during the Great Depression
Authors: Kennedy Christopher A. 
Published: December 2024

AbstractStatistical tests are used to examine the role of prices for petroleum, coal, and farm products in the Great Depression. A new empirical mapping of relationships between monthly energy and farm product prices and key macroeconomic variables shows how biophysical factors intersected with the price system in the 1930s US economy. Deflation was a critical feature of the Depression, with the US aggregate wholesale price index falling by 37 percentage points between October 1929 and February 1933. Petroleum product prices and farm product prices can explain 89% of changes to the aggregate wholesale price index over the 1930s. Granger causality tests show that petroleum product prices led changes to money supply in the 1930s, by 8 months, while farm product and all‐commodities prices Granger caused changes to industrial production. Changes in prices from October 1929 to February 1933 varied substantially between commodities, with prices of coal, metals, and building materials—the essential ingredients for capital formation—all increasing in real terms. Real bituminous coal prices are found to Granger cause changes to money supply, personal income, and industrial production over the 1930s. Overall, the results add further support to the hypothesis that the Great Depression was caused by an energy transition, following discovery of large quantities of petroleum in the US Southwest.
Observational study of the third delay in emergency obstetric triage at the referral national hospital in Tanzania: Baseline survey
Authors: Mahungururo Mugara Joseph , Horiuchi Shigeko , Shishido Eri 
Published: December 2024

AbstractAimThis study aimed to grasp the third delay using an observational method of actual nurses/midwives' practice overtime during care provision to emergency obstetric patients in a tertiary referral national hospital.MethodsA prospective quantitative design was employed to observe the 24‐h obstetric triage process from February 4 to March 7, 2023.ResultsThis study involved observations of 120 obstetric patients with mean maternal age of 29.1 years (SD = 5.5); 81.6% were between 20 and 35 years, 14.2% were over 35 years, and 4.2% were under 20 years. There were 99 (82.5%) pregnant women: 67.7% were preterm, 29.3% term, and 3% postdate, and there were 21 (17.5%) postpartum women. Initial diagnoses were postpartum hemorrhage, 9 (7.5%), antepartum hemorrhage, 15 (12.5%), eclampsia, 13 (10.8), severe preeclampsia, 19 (15.9), preeclampsia, 12 (10%), obstructed labor, 3 (2.5%), previous scar, 13 (10.8%), and others, 36 (30%). Waiting time was within 15 minutes for 30.8% of the observations. Median waiting time from registration to consultation was 9 min. Interquartile range (IQR) for postpartum hemorrhage was 3.5–23.5 min, and IQR for eclampsia was 11.5–117.5. There were no maternal deaths during the 24‐h observation of each obstetric patient.ConclusionThe obstetric triage process requires additional training for triaging time‐sensitive obstetric complications; the wide IQR of waiting time indicated management misalignments thus causing the third delay. The clinical priority of obstetric patients with leading risk factors for morbidity and mortality, such as hypertensive disorders of pregnancy and hemorrhage, needs to be approached within a continuum of care.
Solution‐Focused Brief Therapy for Improving Couple Dyadic Relationships in Iran: A Systematic Review
Authors: Naseh Mitra , Badiezadeh Sahar , Rafieifar Maryam , Taridashti Sarvenaz , Reddy Swathi M. , Panisch Lisa S. 
Published: December 2024

ABSTRACTDespite the popularity of Solution‐Focused Brief Therapy (SFBT) in Iran, the existing literature synthesis has limitations due to the reliance on studies published primarily in Farsi. This systematic review addresses these gaps by synthesizing and evaluating the effectiveness of SFBT on the marital outcomes of couples in Iran, incorporating both Farsi and English sources. The search for this review yielded 1523 records, from which 26 randomized controlled trials were included. The participants across the included studies (n = 1110) were predominantly married women and couples experiencing marital discord, from varied educational backgrounds across multiple Iranian cities. SFBT, primarily delivered in a group format, demonstrated medium to large effect sizes in improving marital outcomes such as dyadic adjustment, satisfaction, and intimacy. However, the presence of bias in study design and reporting necessitates caution in interpreting findings. This review highlights the potential of SFBT to improve marital relationships within the Iranian context.
Recommendations on Ultrasound‐Guided Hyaluronic Acid Soft Tissue Augmentation of the Upper Face in Asians
Authors: Jung Jae Yoon , Choi Hosung , Han Sang Chul , Wanitphakdeedecha Rungsima , Luo Qian , Zhou Lijun , No Jung Im , Jang Woonji E. , Kim Hee‐Jin 
Published: December 2024

ABSTRACTBackgroundUltrasonography allows real‐time imaging of facial soft tissue during hyaluronic acid (HA) filler injections. However, there is currently limited guidance relating to ultrasound‐guided HA filler placement in the upper face.AimsTo develop guidance for the effective use of ultrasonography to improve the safety of HA filler injection procedures.MethodsThrough a series of online video conferences and anatomical studies conducted on a model and a cadaveric specimen, specialists from Korea, Thailand, and China drew recommendations for ultrasound‐guided filler injections of the upper face.ResultsThe authors outlined critical anatomical landmarks for safe HA filler placement to correct volume deficits or treat hollowness of the forehead, temple, and upper eyelids. They provide insights on treatment indications and injection techniques using ultrasound for safe HA filler placement. The recommendations are presented in this paper.ConclusionsWhere there are anatomic variations in the vasculature of the forehead, temple, and periorbital area, ultrasound‐guided filler placement can provide an additional safety measure. Current evidence may give rise to standard practices incorporating ultrasound in injection protocols for the preventive and therapeutic management of adverse events.
The gendered economic consequences of forming a single‐parent household after separation
Authors: Fadel Luisa , Boertien Diederik , Schnor Christine 
Published: December 2024

AbstractObjectiveTo document gender differences in income trajectories before and after forming a single‐parent household following separation in Belgium between 2005 and 2018.BackgroundPrevious research has shown that the economic consequences of partnership dissolution are less severe for fathers than for mothers because of the greater likelihood for women to live with children after separation than men. However, it remains unclear how economic conditions change when men live with children after partnership dissolution.MethodCombining information from the Belgian National Register and the Tax‐register over 14 years, we estimate time‐distributed fixed effects (TDFE) models on a sample of 47,496 men and 151,389 women to investigate how the transition into a single‐parent household after separation impacts equivalized household income, as well as other income measures, from 5 years before to 5 years after the event.ResultsOverall, there is an economic disadvantage related to becoming a single parent co‐residing with children after separation for both men and women. Hence, single fathers are at risk of economic vulnerability, but, after transitioning into a single‐parent household, men lose less in terms of partner income and are faster to recover in terms of couple and equivalized household income than women do.ConclusionMen experience important drops in income after becoming a single parent co‐residing with children, but drops in income are greater for women.
The Role of Resident‐Place Identification in Mediating Consumption Localism and Mobility Intentions
Authors: Leicht Thomas , Giovanardi Massimo , Darler William , Kavaratzis Mihalis 
Published: December 2024

ABSTRACTResidents' personal identification with places (regions, cities, towns, and so on) and with what places are supposed to stand for often determines their place‐supportive attitudes and behaviors. However, little is known about how residents' identification with the characteristics of places and their adoption of place‐related norms and values specifically affect residential mobility intentions and pro‐local consumption tendencies, which are key topics in many spatial development plans and place marketing. The present study addresses this gap in the literature by using a structural equation modeling approach and a cross‐place survey in Germany with 612 residents. The findings show that resident‐place identification, on the basis of residential need satisfaction, increases residents' intentions to stay in a place and pro‐local consumption preferences. These findings suggest that spatial planners and public managers can support the socioeconomic development of cities and regions and increase residents' willingness to stay in a place by strengthening their individual identification with places. We discuss the implications of our findings for the marketing and branding of places.
Immaturity of gut functions and induction of tolerance during early infancy
Authors: Ohtsuka Yoshikazu , Shimizu Toshiaki 
Published: December 2024

AbstractTolerance to foreign molecules is primarily induced through three pathways: anergy, active suppression, and clonal deletion. The immaturity of gut functions, including digestion and barrier protection against foreign molecules during early infancy, is closely linked to the induction of tolerance. A significant number of undigested peptides can pass through leaky gut walls during this period, making it an opportune time to introduce active suppression and clonal deletion in the intestine. Increased production and expression of TGF‐β and CXCL13 with lymphoid hyperplasia in early infancy can be a convenient way to introduce tolerance and immunoglobulin A (IgA) synthesis against food and other antigens to protect hosts from allergic diseases. In this article we will discuss the immaturity of gut functions and mucosal immunity in infancy and its relationship to the introduction of tolerance.
Enhancing Bovine Reproduction: The Progress of Artificial Insemination in Ethiopia
Authors: Hambisa Abdi Bedassa 
Published: December 2024

ABSTRACTArtificial insemination (AI) has emerged as a transformative technology in bovine reproduction, revolutionising the agricultural sector globally. In countries like Ethiopia, where livestock is a vital component of the economy and plays a crucial role in ensuring food security and supporting rural livelihoods, advancements in AI hold immense promise and potential. AI has been instrumental in improving the genetic quality of bovine populations, increasing milk and meat production, and facilitating the dissemination of superior genetic traits across diverse breeds. In Ethiopia, traditional breeding practices often face challenges related to limited access to superior breeding stock and inadequate breeding management. The adoption of AI techniques can address these constraints and pave the way for sustainable livestock development. The importance of bovine AI in Ethiopia is underscored by the country's large bovine population, which primarily consists of indigenous zebu cattle breeds known for their adaptability to local environmental conditions. However, challenges persist regarding its widespread adoption and implementation in Ethiopia. Key obstacles include limited access to quality semen from superior sires, inadequate infrastructure and facilities for AI services, insufficient training and capacity building among veterinary professionals and inseminators, and socioeconomic barriers faced by smallholder farmers in accessing AI services. This review aims to critically examine the progress made in bovine AI in Ethiopia, identify the obstacles and constraints hindering its full‐scale adoption, and explore prospects and strategies for overcoming these challenges. By delving into the latest research findings, policy frameworks and practical experiences in bovine AI, this review seeks to provide valuable insights and recommendations for leveraging AI technology to enhance livestock productivity, genetic diversity and sustainable agricultural development in Ethiopia.
Leadership in Scholarship: Editors' Appointments and Scientific Narrative
Authors: Önder Ali Sina , Popov Sergey V. , Schweitzer Sascha 
Published: December 2024

ABSTRACTAcademic journals disseminate new knowledge and therefore can influence the direction and composition of ongoing research by choosing what to publish. We study the change in the topic structure of papers published in the American Economic Review (AER) after the appointments of editors and coeditors of the AER between 1985 and 2011 using a textual analysis of accepted publications. The change due to the appointment of new AER editors, we find, is not an indicator of editors' personal taste in topics, but rather indicates the desire of those who appoint editors to premediate trends in other Top 5 journals.
Supplemental Material: The two-sided continental subduction of the Adria microplate (Mediterranean)
Authors: Menichelli Irene , al. et 
Published: December 2024

<p>Additional figures (S1–S5) and a text analyzing Vp and Vp/Vs perturbations at lithospheric mantle depths, synthetic slab test beneath the Dinarides, checkerboard and recovery tests for the Adria plate, comparisons with previous tomographic studies, and a detailed discussion of the observed velocity anomalies and model comparisons. </p>
Comparative effectiveness and safety of single inhaler triple therapies for chronic obstructive pulmonary disease: new user cohort study
Authors: Feldman William B , Suissa Samy , Kesselheim Aaron S , Avorn Jerry , Russo Massimiliano , Schneeweiss Sebastian , Wang Shirley V 
Published: December 2024

Abstract

Objective
To compare the effectiveness and safety of budesonide-glycopyrrolate-formoterol, a twice daily metered dose inhaler, and fluticasone-umeclidinium-vilanterol, a once daily dry powder inhaler, in patients with chronic obstructive pulmonary disease (COPD) treated in routine clinical practice.

Design
New user cohort study.

Setting
Longitudinal commercial US claims data.

Participants
New initiators of budesonide-glycopyrrolate-formoterol or fluticasone-umeclidinium-vilanterol between 1 January 2021 and 30 September 2023 who had a diagnosis of COPD and were aged 40 years or older.

Main outcome measures
In this 1:1 propensity score matched study, the main outcome measures were first moderate or severe COPD exacerbation (effectiveness) and first admission to hospital with pneumonia (safety) while on treatment. Potential confounders were measured in the 365 days before cohort entry and included in propensity scores. Hazard ratios and 95% confidence intervals (CIs) were estimated using a Cox proportional hazards regression model.

Results
The study cohort included 20 388 propensity score matched pairs of new users initiating single inhaler triple therapy. Patients who received budesonide-glycopyrrolate-formoterol had a 9% higher incidence of first moderate or severe COPD exacerbation (hazard ratio 1.09 (95% CI 1.04 to 1.14); number needed to harm 38) compared with patients receiving fluticasone-umeclidinium-vilanterol and an identical incidence of first admission to hospital with pneumonia (1.00 (0.91 to 1.10)). The hazard of first moderate COPD exacerbation was 7% higher (1.07 (1.02 to 1.12); number needed to harm 54) and the hazard of first severe COPD exacerbation 29% higher (1.29 (1.12 to 1.48); number needed to harm 97) among those receiving budesonide-glycopyrrolate-formoterol compared to fluticasone-umeclidinium-vilanterol. Prespecified sensitivity analyses yielded similar findings to the primary analysis.

Conclusions
Budesonide-glycopyrrolate-formoterol was not associated with improved clinical outcomes compared with fluticasone-umeclidinium-vilanterol. Given the added climate impact of metered dose inhalers, health systems seeking to decrease use of these products may consider steps to promote further prescribing of fluticasone-umeclidinium-vilanterol compared with budesonide-glycopyrrolate-formoterol in people with COPD.

Study registration

Center for Open Science Real World Evidence Registry (
https://osf.io/6gdyp/
).
Quantitative evaluation of GPT-4’s performance on US and Chinese osteoarthritis treatment guideline interpretation and orthopaedic case consultation
Authors: Li Juntan , Gao Xiang , Dou Tianxu , Gao Yuyang , Li Xu , Zhu Wannan 
Published: December 2024

ObjectivesTo evaluate GPT-4’s performance in interpreting osteoarthritis (OA) treatment guidelines from the USA and China, and to assess its ability to diagnose and manage orthopaedic cases.SettingThe study was conducted using publicly available OA treatment guidelines and simulated orthopaedic case scenarios.ParticipantsNo human participants were involved. The evaluation focused on GPT-4’s responses to clinical guidelines and case questions, assessed by two orthopaedic specialists.OutcomesPrimary outcomes included the accuracy and completeness of GPT-4’s responses to guideline-based queries and case scenarios. Metrics included the correct match rate, completeness score and stratification of case responses into predefined tiers of correctness.ResultsIn interpreting the American Academy of Orthopaedic Surgeons and Chinese OA guidelines, GPT-4 achieved a correct match rate of 46.4% and complete agreement with all score-2 recommendations. The accuracy score for guideline interpretation was 4.3±1.6 (95% CI 3.9 to 4.7), and the completeness score was 2.8±0.6 (95% CI 2.5 to 3.1). For case-based questions, GPT-4 demonstrated high performance, with over 88% of responses rated as comprehensive.ConclusionsGPT-4 demonstrates promising capabilities as an auxiliary tool in orthopaedic clinical practice and patient education, with high levels of accuracy and completeness in guideline interpretation and clinical case analysis. However, further validation is necessary to establish its utility in real-world clinical settings.
Co-designing a low-intensity psychological therapy for fear of recurrence in psychosis using translational learning from fear of recurrence in oncology: protocol for intervention development for future testing in a feasibility study
Authors: Allan Stephanie , Sinclair Fiona , Correia Marta , Fragkandrea-Nixon Ioanna , Phiri Alie , Jones Gareth , Thomson David , Yanga Francis , Brown George , McCann Mark , Simpson Sharon Anne , Evans Jonathan , Robb Katie , Gumley Andrew 
Published: December 2024

Introduction

Fear of recurrence is a transdiagnostic problem experienced by people with psychosis, which is associated with anxiety, depression and risk of future relapse events. Despite this, there is a lack of available psychological interventions for fear of recurrence, and psychological therapies for schizophrenia are often poorly implemented in general. However, low-intensity psychological therapy is available for people who experience fear of recurrence in the context of cancer, which means there is an opportunity to learn what has worked in a well-implemented psychological therapy to see if any learning can be adapted for schizophrenia care. This article describes the design, methods and expected data collection of development, acceptab

i

lity, feasibility, a

n

d preliminary outcome signals for a copro

d

uced low-intensity psycholo

g

ical intervention targeting fear

o

f relapse in people with schizophrenia (INDIGO), which aims to develop an acceptable psychological intervention for fear of recurrence.

Methods and analysis
INDIGO will use a mixed-methods approach to co-design and deliver a model and treatment pathway for a psychological intervention for people diagnosed with schizophrenia who experience fear of recurrence. The study will consist of four stages. First, in-depth interviews with mental health staff and people diagnosed with schizophrenia (with a further social network mapping task for patient participants only) to develop the intervention. Second, in-depth interviews with people who have accessed the Glasgow Fear of Recurrence service and oncology staff will be conducted to inform further development of the intervention. Third, co-design workshops will be held with people diagnosed with schizophrenia and mental health staff to co-design intervention content and the treatment pathway. Finally, people diagnosed with schizophrenia will be presented with an intervention prototype and invited to complete ‘think-aloud’ interviews to gather further feedback so adaptations can be implemented.

Ethics and dissemination
The INDIGO study received ethical approval from East Midlands—Nottingham 2 Research Ethics Committee (24/EM/0124). The study received independent peer review prior to funding. This co-design study is expected to lead to a future feasibility study and, if indicated, a randomised controlled trial.