bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis Sistem Pengembangan Layanan Transportasi Online Terhadap Kepuasan Konsumen di Kota Kendari
Authors: Ija La 
Published: January 2021

Penelitian ini bertujuan untuk mengetahui bagaimana profil konsumen Go- Jek dan GrabCar di Kota Kendari, selain itu untuk mengetahui apakah ada perbedaan persepsi konsumen terhadap kualitas pelayanan, harga dan kepuasan konsumen Go-Jek dan GrabCar di Kota Kendari. Purposive sampling adalah teknik pengambilan sampel dalam penelitian ini. Data penelitian diperoleh dengan membagikan kuesioner penelitian tentang kualitas pelayanan, harga, dan kepuasan konsumen, kepada 50 responden atau lebih . Uji paired Sampel T-Test dan Uji Wilcoxon adalah teknik analisis data dalam penelitian ini dengan menggunakan aplikasi IBM SPSS Statistik . Hasil Penelitian menunjukkan bahwa: (1) mayoritas Pelanggan Go-Jek dan GrabCar di Kota Kendari adalah perempuan , usia 15-20 tahun, pendidikan Menengah SMP, dan memiliki pekerjaan sebagai pelajar/mahasiswa, dan berpendapatan ≥ Rp 500.000 per bulan, (2) tidak terdapat perbedaan persepsi kualitas pelayanan Go-Jek dan GrabCar, (3) terdapat perbedaan persepsi harga Go-Jek dan GrabCar, (4) terdapat Perbandingan antara Pelayanan Go-Jek dan GrabCar di Kota Kendari.
Perancangan Alat Pendeteksi Kebocoran Gas LPG Menggunakan Sensor MQ-2 Berbasis Arduino
Authors: Inggi Rahmat , Pangala Jeri 
Published: January 2021

Saat ini penggunaan gas LPG memang sangat berpengaruh besar pada masayrakat bahkan hampir seluruh masyarakat Indoneisia menggunakan Gas LPG untuk kebutuhan sehari-hari sebagai alat memasak. Dari penggunaanya yang sangat membantu dan ramah lingkungan ada juga resiko dan masalah yang bisa mengakibatkan kebakaran akibat kebocorann tabung Gas LPG, saat ini banyak kebakaran yang terjadi akibat kebocoran Gas LPG. Perancangan alat pendeteksi kebocoran gas LPG menggunakan sensor MQ-2 berbasis arduino, Alat ini dapat mendeteksi gas yang bocor dan secara otomatis juga akan memberikan infor masih lewat tampilan di layar LCD, bunyi Buzzer sebagi alarm, dan Mengirimkan SMS ke nomor HP yang di input pada program. Alat ini di rancang untuk mengurangi kebakran akibat kebocoran tabung Gas LPG yang sering terjadi dan juga sebagai solusi yang untuk mencegah kerugian akibat kebakaran tabung Gas LPG dan juga untuk mencegah koban jiwa akibat kebakaran karena kebocoran tabung gas LPG. Untuk penelitian selanjutnya diharapkan dapat mengembangkan alat ini dengan mebuat aplikasi Smartphone Android untuk kendali sensor gas LPG jarak jauh.
Due voci sul mar Nero: Luca Desiato alla (ri)scoperta dell’esilio ovidiano
Authors: D’Alfonso Dalila 
Published: January 2021

Le elegie dei Tristia e delle Epistulae ex Ponto rappresentano, ancora oggi, un riferimento imprescindibile per quanti vogliano indagare l’esperienza esilica in tutte le sue sfaccettature e in tutta la sua complessità. Non a caso, numerosi autori della contemporaneità hanno guardato alla poesia tomitana dell’ultimo Ovidio come a un vero e proprio paradigma per le scritture da e sull’esilio di ogni tempo. Nei quarantaquattro capitoli in cui articola il romanzo Sulle rive del Mar Nero (1992), Luca Desiato “scompone” l’animo umano toccato dalla sorte dell’esilio, un esilio che si presenta come condanna soprattutto interiore. Il protagonista, uno scrittore che vive l’ultimo corso della sua esistenza nella Roma borghese degli anni Novanta, alterna la propria voce a quella del poeta romano, condannato da Augusto nell’8 d.C. alla relegatio perpetua. Saverio rappresenta, in primis, un esule dell’esistenza, un prigioniero del tempo ultimo che sta vivendo, un tempo estremo, come le terre del Ponto Eusino.
Copper‐Catalyzed Decarboxylative Alkylselenation of Propiolic Acids with Se Powder and Epoxides
Authors: Yao Yujing , Wang Caihong , Ma Yunfei , Zhang Jintao , Sun Dong , Chen Luya , Huang Lehao , Wu Ge 
Published: February 2021

AbstractA copper‐catalyzed decarboxylative alkylselenation of propiolic acids with Se powder and epoxides leading to alkynyl selenides is developed. This protocol not only provides an approach to obtain alkynyl selenides with the formation of double C−Se bonds, but also expands the applicability of alkynyl carboxylic acid.magnified image
Radiogenomics of gastroenterological cancer: The dawn of personalized medicine with artificial intelligence‐based image analysis
Authors: Hoshino Isamu , Yokota Hajime 
Published: February 2021

AbstractRadiogenomics is a new field of medical science that integrates two omics, radiomics and genomics, and may bring a major paradigm shift in traditional personalized medicine strategies that require tumor tissue samples. In addition, the acquisition of the data does not require special imaging equipment or special imaging conditions, and it is possible to use image information from computed tomography, magnetic resonance imaging, positron emission tomography‐computed tomography in clinical practice, so the versatility and cost‐effectiveness of radiogenomics are expected. So far, the field of radiogenomics has developed, especially in the fields of brain tumors and breast cancer, but recently, reports of radiogenomic research on gastroenterological cancer are increasing. This review provides an overview of radiogenomic research methods and summarizes the current radiogenomic research in gastroenterological cancer. In addition, the application of artificial intelligence is considered to be indispensable for the integrated analysis of enormous omics information in the future, and the future direction of this research, including the latest technologies, will be discussed.
Biodegradation of heavy oil by fungal extracellular enzymes fromAspergillusspp. shows potential to enhance oil recovery
Authors: Zhang Junhui , Gao Hui , Lai Hangxian , Hu Shibin , Xue Quanhong 
Published: February 2021

AbstractMicrobial enhanced oil recovery makes a substantial contribution to the recovery of heavy oils; however, most methods use bacteria, with less attention paid to the potential of fungi. In this study, we investigated the efficiency of fungal extracellular enzymes in biotransformation of heavy oil fractions into light compounds. TwoAspergillusisolates (A. terreusandA. nidulans) with the ability to biodegrade heavy oil were isolated from bitumen. The extracellular enzymes from theseAspergillusisolates exhibited dehydrogenase and catechol 2,3‐dioxygenase activities. The biodegradation of heavy oil was coupled with abundant production of gases, mainly CO2and H2. Gas chromatography analysis revealed a redistribution ofn‐alkanes in heavy oil after treatment with crude enzyme extracts, which resulted in an increase in individualn‐alkanes. The viscosity of heavy oil was decreased considerably by enzymatic degradation. These results demonstrate the potential of fungal extracellular enzymes fromAspergillusspp. for applications in enhanced heavy oil recovery.
Mass transfer advantage of hierarchical structured cobalt‐based catalyst pellet for Fischer–Tropsch synthesis
Authors: Niu Congcong , Li Hansheng , Xia Ming , Wang Jungang , Chen Congbiao , Ma Zhongyi , Jia Litao , Hou Bo , Li Debao 
Published: February 2021

AbstractThe low effectiveness factor of catalyst pellet caused by high internal diffusion limitation is a common issue in fixed‐bed reactor. Nevertheless, hierarchical structured catalyst provides a promising solution for the contradiction between reaction activity and diffusion efficiency in large catalyst pellets. Herein, we studied the effect of pore structure parameters of the meso‐macroporous catalyst on Fischer–Tropsch synthesis performances through experiment and pellet scale reaction–diffusion simulation. The pellet simulation firstly elucidated the reason for the significant improvement on activity and product selectivity for the meso‐macroporous catalyst observed in our experiment. Further optimization via pellet simulation indicated the critical influences of wax filling degree and that the perfect matching between reaction and mass transfer rates by increasing macropore size and adjusting porosity within pellet enables the C5+ space–time yield to the maximum. This work could provide a theoretical guideline for the engineering design of the hierarchical structured catalyst pellet.
Benefits of biologic therapy administered for asthma on co‐existent chronic rhinosinusitis: A real‐world study
Authors: Bajpai Shilpika , Marino Michael J. , Rank Matthew A. , Donaldson Angela M. , O'Brien Erin K. , Lal Devyani 
Published: February 2021

BackgroundAsthma and some chronic rhinosinusitis (CRS) subtypes are mediated by similar pathophysiologic mechanisms. The purpose of this study was to evaluate the effects of biologic therapy for asthma on co‐existent CRS in the “real‐world” setting.MethodsA review of electronic health records (2016‐2019) at Mayo Clinic was conducted to identify asthma patients treated with biologics who had co‐existent CRS. Matched‐pair analyses compared pretherapy and posttherapy Lund‐Mackay computed tomography (CT) scores and 22‐item Sino‐Nasal Outcome Test (SNOT‐22) scores. Performance of endoscopic sinus surgery (ESS) after initiating biologics was studied.ResultsWe identified 247 patients who received anti‐asthma biologic therapy and had co‐existent CRS. Of these, 181 patients (73.3%) had CRS with nasal polyposis (CRSwNP) and 66 (26.7%) had CRS without nasal polyposis (CRSsNP). The biologics utilized were omalizumab (51.0%), mepolizumab (46.6%), benralizumab (10.5%), reslizumab (1.6%), and dupilumab (2.4%). Anti‐interleukin‐5 (anti‐IL‐5) intervention was associated with significant improvement in CT scores (CRS overall, CRSwNP subgroup, CRSsNP subgroup) and SNOT‐22 scores (CRS overall, CRSwNP subgroup). Patients on omalizumab had a decrease in CT scores, but not SNOT‐22 scores. ESS was performed in 206 patients (84.1%); 55 (22.3%) underwent surgery post–biologic intervention (anti‐IL‐5: 16.5%; omalizumab 27.8% of patients).ConclusionAnti‐IL‐5 agents were associated with improved CT and SNOT‐22 scores in the overall CRS group and in CRSwNP subgroup; CRSsNP patients showed improved CT scores only. Omalizumab improved CT but not SNOT‐22 scores. ESS was performed in 22% of patients after initiating biologics. These real‐world results may influence future trial designs and clinical applications of biologics for CRS. ©2021 ARSAAOA, LLC.
Generalizability of findings from a clinical sample to a community‐based sample: A comparison of ADNI and ARIC
Authors: Gianattasio Kan Z. , Bennett Erin E. , Wei Jingkai , Mehrotra Megha L. , Mosley Thomas , Gottesman Rebecca F. , Wong Dean F. , Stuart Elizabeth A. , Griswold Michael E. , Couper David , Glymour M. Maria , Power Melinda C. ,   for the Alzheimer's Disease Neuroimaging Initiative
Published: February 2021

AbstractIntroductionClinic‐based study samples, including the Alzheimer's Disease Neuroimaging Initiative (ADNI), offer rich data, but findings may not generalize to community‐based settings. We compared associations in ADNI to those in the Atherosclerosis Risk in Communities (ARIC) study to assess generalizability across the two settings.MethodsWe estimated cohort‐specific associations among risk factors, cognitive test scores, and neuroimaging outcomes to identify and quantify the extent of significant and substantively meaningful differences in associations between cohorts. We explored whether using more homogenous samples improved comparability in effect estimates.ResultsThe proportion of associations that differed significantly between cohorts ranged from 27% to 34% across sample subsets. Many differences were substantively meaningful (e.g., odds ratios [OR] for apolipoprotein E ε4 on amyloid positivity in ARIC: OR = 2.8, in ADNI: OR = 8.6).DiscussionA higher proportion of associations differed significantly and substantively than would be expected by chance. Findings in clinical samples should be confirmed in more representative samples.
Planar Hexacoordinate Carbons: Half Covalent, Half Ionic
Authors: Leyva‐Parra Luis , Diego Luz , Yañez Osvaldo , Inostroza Diego , Barroso Jorge , Vásquez‐Espinal Alejandro , Merino Gabriel , Tiznado William 
Published: February 2021

AbstractHerein, the first global minima containing a planar hexacoordinate carbon (phC) atom are reported. The fifteen structures belong to the CE3M3+ (E=S–Te and M=Li–Cs) series and satisfy both geometric and electronic criteria to be considered as a true phC. The design strategy consisted of replacing oxygen in the D3h CO3Li3+ structure with heavy and less electronegative chalcogens, inducing a negative charge on the C atom and an attractive electrostatic interaction between C and the alkali‐metal cations. The chemical bonding analyses indicate that carbon is covalently bonded to three chalcogens and ionically connected to the three alkali metals.
Perovskite Oxide–Halide Solid Solutions: A Platform for Electrocatalysts
Authors: Wang Tao , Fan Juntian , Do‐Thanh Chi‐Linh , Suo Xian , Yang Zhenzhen , Chen Hao , Yuan Yating , Lyu Hailong , Yang Shize , Dai Sheng 
Published: February 2021

AbstractThe successful integration or hybridization of perovskite oxides with their halide cousins would enable the formation of both multi‐anionic and multi‐cationic solid solutions with unique metal‐ion sites and synergistic properties that could potentially surpass the performance of classic perovskites. However, such solid solutions had not been produced previously owing to their distinct formation energies and different synthesis conditions. Solid solutions combining perovskite oxides with fluorides were produced in this study by mechanochemical synthesis. The obtained perovskite oxide–halide solid solutions had highly mixed elements and valences, uniform element distributions, and single‐phase crystalline structures. The solid solution with an optimized combination of oxides and fluorides exhibited enhanced catalytic performance in the oxygen evolution reaction.
Controlling Energy Gaps of π‐Conjugated Polymers by Multi‐Fluorinated Boron‐Fused Azobenzene Acceptors for Highly Efficient Near‐Infrared Emission
Authors: Gon Masayuki , Wakabayashi Junko , Nakamura Masashi , Tanaka Kazuo , Chujo Yoshiki 
Published: February 2021

AbstractWe demonstrate that multi‐fluorinated boron‐fused azobenzene (BAz) complexes can work as a strong electron acceptor in electron donor‐acceptor (D‐A) type π‐conjugated polymers. Position‐dependent substitution effects were revealed, and the energy level of the lowest unoccupied molecular orbital (LUMO) was critically decreased by fluorination. As a result, the obtained polymers showed near‐infrared (NIR) emission (λPL=758–847 nm) with high absolute photoluminescence quantum yield (ΦPL=7–23%) originating from low‐lying LUMO energy levels of the BAz moieties (−3.94 to −4.25 eV). Owing to inherent solid‐state emissive properties of the BAz units, deeper NIR emission (λPL=852980 nm) was detected in film state. Clear solvent effects prove that the NIR emission is from a charge transfer state originating from a strong D‐A interaction. The effects of fluorination on the frontier orbitals are well understandable and predictable by theoretical calculation with density functional theory. This study demonstrates the effectiveness of fluorination to the BAz units for producing a strong electron‐accepting unit through fine‐tuning of energy gaps, which can be the promising strategy for designing NIR absorptive and emissive materials.
A review of collision detection for deformable objects
Authors: Wang Monan , Cao Jiaqi 
Published: February 2021

AbstractIn the process of simulating and modeling real objects, the phenomenon of objects penetrating each other may occur in the model, which is unrealistic and then the research of collision detection (CD) is generated. As a bottleneck of virtual environment simulation, researchers have conducted in‐depth research on CD, especially the CD of deformable objects. In this paper, we briefly review the related research on CD of deformable objects regarding relevant literature. First, we briefly introduce previous reviews of CD. Second, we review the popular research methods and limitations of CD between deformable objects. Third, we review the popular research methods and limitations of self‐collision detection in deformable objects. Finally, we discuss future directions of development. This review can be used as a reference for the application of CD in all directions.
The fucose‐specific lectin ANL from Aspergillus niger possesses anti‐cancer activity by inducing the intrinsic apoptosis pathway in hepatocellular and colon cancer cells
Authors: Jagadeesh Narasimhappagari , Belur Shivakumar , Campbell Barry J. , Inamdar Shashikala R. 
Published: February 2021

AbstractThe L‐fucose‐specific lectin from Aspergillus niger (ANL), isolated from the corneal smears of a keratitis patient was reported earlier. Here, we examined the interaction of ANL with human hepatocellular and colon cancer cells, evaluated its anti‐cancer activity and diagnostic potential to detect aberrantly glycosylated tumour‐associated serum glycoproteins such as alpha‐fetoprotein (AFP). We observed that ANL strongly bound to both HepG2 and HT‐29 cell‐lines and this interaction was effectively blocked with L‐fucose and mucin in a dose and time‐dependent manner with an IC50 of 1.25 and 5 μg/mL for HepG2 and HT‐29 cells respectively at 48 hours. ANL treatment increased hypodiploidy and decreased the number of HepG2 cell in G0‐G1 phase at both 24 and 48 hours. Furthermore, ANL increased the level of apoptosis in both HepG2 and HT‐29 cells in a time‐dependent manner via enhanced production of reactive oxygen species and altered mitochondrial membrane potential, indicative of intrinsic apoptotis pathway activation. Immunoblot analysis confirmed the time‐dependent elevation of levels of cytochrome c, initiator caspase‐9 and activation of caspase‐3. ANL immunohistochemistry on colon cancer tissue and quantification of AFP in HCC patient serum samples by developing an ANL‐anti‐AFP antibody sandwich enzyme‐linked immunosorbent assay confirmed the diagnostic potential of ANL. Here, interaction of ANL with AFP could be effectively blocked in the presence of competing fucose‐bearing glycans. We found ANL to be more sensitive than Lens culinaris lectin, a well‐known fucose‐specific lectin and currently used diagnostic agent. ANL can be further explored as a diagnostic and anti‐cancer agent.
Expanding the Biocatalytic Toolbox with a New Type of ene/yne‐Reductase from Cyclocybe aegerita
Authors: Karrer Dominik , Gand Martin , Rühl Martin 
Published: February 2021

AbstractThis study introduces a new type of ene/yne‐reductase from Cyclocybe aegerita with a broad substrate scope including aliphatic and aromatic alkenes/alkynes from which aliphatic C8‐alkenones, C8‐alkenals and aromatic nitroalkenes were the preferred substrates. By comparing alkenes and alkynes, a ∼2‐fold lower conversion towards alkynes was observed. Furthermore, it could be shown that the alkyne reduction proceeds via a slow reduction of the alkyne to the alkene followed by a rapid reduction to the corresponding alkane. An accumulation of the alkene was not observed. Moreover, a regioselective reduction of the double bond in α,β‐position of α,β,γ,δ‐unsaturated alkenals took place. This as well as the first biocatalytic reduction of different aliphatic and aromatic alkynes to alkanes underlines the novelty of this biocatalyst. Thus with this study on the new ene‐reductase CaeEnR1, a promising substrate scope is disclosed that describes conceivably a broad occurrence of such reactions within the chemical landscape.
Probing the Local Reaction Environment During High Turnover Carbon Dioxide Reduction with Ag‐Based Gas Diffusion Electrodes
Authors: Dieckhöfer Stefan , Öhl Denis , Junqueira João R. C. , Quast Thomas , Turek Thomas , Schuhmann Wolfgang 
Published: February 2021

AbstractDiscerning the influence of electrochemical reactions on the electrode microenvironment is an unavoidable topic for electrochemical reactions that involve the production of OH− and the consumption of water. That is particularly true for the carbon dioxide reduction reaction (CO2RR), which together with the competing hydrogen evolution reaction (HER) exert changes in the local OH− and H2O activity that in turn can possibly affect activity, stability, and selectivity of the CO2RR. We determine the local OH− and H2O activity in close proximity to a CO2‐converting Ag‐based gas diffusion electrode (GDE) with product analysis using gas chromatography. A Pt nanosensor is positioned in the vicinity of the working GDE using shear‐force‐based scanning electrochemical microscopy (SECM) approach curves, which allows monitoring changes invoked by reactions proceeding within an otherwise inaccessible porous GDE by potentiodynamic measurements at the Pt‐tip nanosensor. We show that high turnover HER/CO2RR at a GDE lead to modulations of the alkalinity of the local electrolyte, that resemble a 16 m KOH solution, variations that are in turn linked to the reaction selectivity.
Precise Synthesis of Carbon Nanotubes and One‐Dimensional Hybrids from Templates†
Authors: Yang Xusheng , Zhao Xin , Liu Tianhui , Yang Feng 
Published: February 2021

AbstractCarbon nanotubes (CNTs) present unique properties determined by their chiral structure. The main hurdle towards the wide applications is the difficulty to control the structure of CNTs and their hybrids that determines the properties. Precise synthesis with well‐defined templates is a promising approach to control the identical structure of carbon nanomaterials. In this review, we summarize main achievements on controlled synthesis of CNTs and hybrids on two aspects: chirality‐specific growth of CNTs from well‐defined catalysts and nanocarbon templates, atomically precise synthesis of one‐dimensional (1D) materials with the templates of CNTs. In the chirality‐controlled growth part, we focus on the design of structural templates and growth mechanisms. In the synthesis of CNT hybrids part, we organize the existing strategies based on types of 1D hybrids templated by CNTs, including confined nanotubes, linear carbon chains, nanowires, quasi‐1D van der‐Waals materials. The main advantages, challenges, and perspectives in further development are discussed.