bluuebunny/crossref_metadata_2025_split huggingface dataset:
Characterization of glass beads from Nanhai I shipwreck and new evidence of lead tin yellow type II in China
Authors: Tian Chenxin , Zhou Yihang , Wang Kai , Sun Jian , Cui Yong , Hu Dongbo 
Published: May 2021

Abstract
Glass beads excavated from Nanhai I shipwreck were investigated with scanning electron microscopy with energy dispersive spectrometer (SEM–EDS), Raman spectroscopy, multi-collector inductively coupled plasma mass spectrometry (MC-ICP-MS) and X-ray diffraction (XRD). Dating back to the Southern Song Dynasty, these beads help to study Chinese maritime trades during the twelfth–thirteenth century. The bead samples are categorized into five groups by color, i.e., yellow, orange-red, blue, dark red and light red. All beads are of K2O-PbO-SiO2 and PbO-SiO2 glass systems and in form of coil bead, which further confirms the Chinese origin of them. Lead tin yellow type II was identified in the opaque yellow coil beads, and K2SnxPb(1-x)Si3O9 crystals were found in both yellow and orange-red samples. Through the preparation of glass with the same formula as the ancient yellow beads, lead tin yellow type II was probably synthesized beforehand and added as colorant because its raw materials tend to form K2SnxPb(1-x)Si3O9 crystals in the K2O-PbO-SiO2 glass during firing. As lead tin yellow type II is an atypical colorant in China, these beads from Nanhai I shipwreck may serve as the first clear evidence of lead tin yellow type II presenting in the Chinese glass system. The lead isotope ratios of the yellow beads suggest they were produced in Fujian Province, China. The introduction of the lead tin yellow coloring technique might have a close connection to the glass making in the Southeast Asia and these beads seemed to be made specifically for overseas markets.
Flood inundation simulations based on GSMaP satellite rainfall data in Jakarta, Indonesia
Authors: Priyambodoho Bambang Adhi , Kure Shuichi , Yagi Ryuusei , Januriyadi Nurul Fajar 
Published: May 2021

AbstractJakarta is the capital of Indonesia and is considered one of the most vulnerable cities to climate-related disasters, including flooding, sea-level rise, and storm surges. Therefore, the development of a flood-forecasting system for Jakarta is crucial. However, the accurate prediction of flooding in Jakarta is challenging because of the short flood concentration time in highly urbanized basins and the shortage of rainfall data in poorly gauged areas. The aim of this study is to simulate recent flood inundation using global satellite mapping of precipitation (GSMaP) products. The GSMaP products (NRT and Gauge V7) were evaluated and compared with hourly observation data from five ground stations in the Ciliwung River Basin. In addition, a rainfall-runoff and flood inundation model was applied to the target basin. The results of the analysis showed that the GSMaP Gauge data were more accurate than the GSMaP NRT data. However, the GSMaP Gauge cannot be used to provide real-time rainfall data and is, therefore, inadequate for real-time flood forecasting. We conclude that the GSMaP Gauge is suitable for replicating past flood events, but it is challenging to use the GSMaP NRT for real-time flood forecasting in Jakarta.
Low dose hCG supplementation in a Gn-RH-agonist trigger protocol is associated with worse pregnancy outcomes: a retrospective cohort study
Authors: Shapiro Maren , Romanski Phillip , Thomas Ann , Lanes Andrea , Yanushpolsky Elena 
Published: May 2021

Abstract
Background
A number of studies have looked at dual triggers with hCG and GnRH agonist (GnRHa) in varying doses, but the question remains: what is the optimal dose of hCG to minimize ovarian hyperstimulation syndrome (OHSS) and still offer adequate pregnancy rates? The purpose of this study was to compare pregnancy and OHSS rates following dual trigger for oocyte maturation with GnRHa and a low-dose hCG versus hCG alone. A secondary objective was the assess pregnancy outcomes in subsequent frozen cycles for the same population.

Methods
A total of 963 women < 41 years old, with a BMI 18–40 kg/m2 and an AMH > 2 ng/mL who underwent fresh autologous in vitro fertilization (IVF) with GnRH antagonist protocol at a University-based fertility center were included in this retrospective cohort study. Those who received a low dose dual trigger with hCG (1000u) and GnRHa (2 mg) were compared to those who received hCG alone (10,000u hCG/250-500 μg Ovidrel). Differences in implantation rates, pregnancy, live birth, and OHSS were investigated.

Results
The dual trigger group was younger (mean 33.6 vs 34.1 years), had a higher AMH (6.3 vs 4.9 ng/mL,) more oocytes retrieved (18.1 vs 14.9) and a higher fertilized oocyte rate (80% vs 77%) compared with the hCG only group. Yet, the dual trigger group had a lower probability of clinical pregnancy (gestational sac, 43.4% vs 52.8%) and live birth (33.4% vs 45.8%), all of which were statistically significant. There were 3 cases of OHSS, all in the hCG-only trigger group. In subsequent frozen cycles, pregnancy rates were comparable between the two groups.

Conclusions
The dual trigger group had a better prognosis based on age and AMH levels and had better stimulation outcomes, but significantly worse pregnancy outcomes, suggesting the low dose hCG (1000u) in the dual trigger may not have provided adequate luteal support, compared to an hCG-only trigger (10,000u hCG/250-500 μg Ovidrel). Interestingly, the pregnancy rates were comparable in subsequent frozen cycles, further supporting the hypothesis that the issue lies in inadequate luteal phase support, rather than embryo quality. Based on these findings, our program has changed the protocol to 1500u of hCG in a dual trigger.
Evidence-based prediction and prevention of cardiovascular morbidity in adults treated for cancer
Authors: Altena Renske , Hubbert Laila , Kiani Narsis A. , Wengström Yvonne , Bergh Jonas , Hedayati Elham 
Published: May 2021

AbstractBackgroundCancer treatment-related morbidity relevantly compromises health status in cancer survivors, and efforts to optimise health-related outcomes in this population are vital to maximising healthy survivorship. A pre-treatment assessment – and possibly preventive management strategies – of cancer patients at increased risk for cardiovascular disease (CVD) seems a rational approach in this regard. Definitive evidence for such strategies is largely lacking, thereby impeding the formulation of firm recommendations.ResultsThe current scoping review aims to summarise and grade the evidence regarding strategies for prediction and prevention of CVD in adults in relation to oncological treatments. We conducted a scoping literature search for different strategies for primary prevention, such as medical and lifestyle interventions, as well as the use of predictive risk scores. We identified studies with moderate to good strength and up to now limited evidence to recommend primary preventive strategies in unselected patients treated with potentially cardiotoxic oncologic therapies.ConclusionEfforts to minimize the CVD burden in cancer survivors are needed to accomplish healthy survivorship. This can be done by means of robust models predictive for CVD events or application of interventions during or after oncological treatments. Up to now there is insufficient evidence to implement preventive strategies in an unselected group of patients treated with potential cardiotoxic oncological treatments. We conclude that randomised controlled trials are needed that evaluate medical and lifestyle interventions in groups at increased risk for complications, in order to be able to influence chronic illness risks, such as cardiovascular complications, for cancer survivors.
Clinic-based Procedures for Headache
Authors: Robbins Matthew S. 
Published: May 2021

ABSTRACT

PURPOSE OF REVIEW
Headache disorders are common and disabling, and many therapies that are effective and safe are procedural.

RECENT FINDINGS
After pivotal clinical trials, onabotulinumtoxinA has become an established preventive therapy for chronic migraine; it is better tolerated than many other treatments and may be useful for other headache disorders. Peripheral nerve blocks, especially greater occipital nerve blocks, have amassed evidence from randomized trials in the acute and short-term preventive treatment of migraine and cluster headache. Trigger point injections and sphenopalatine ganglion blocks have recent trials suggesting efficacy and safety in properly selected patients. Medical education initiatives are needed to train neurologists in these procedures to help manage the large population of patients with headache disorders who need them.

SUMMARY
Evidence exists for the efficacy and safety of procedural therapies to be incorporated into neurology practice for the management of patients with migraine, cluster headache, and other headache disorders.
Other Primary Headache Disorders
Authors: Smith Jonathan H. 
Published: May 2021

ABSTRACT

PURPOSE
This article provides an overview of a diverse group of primary headache disorders that are categorized in the International Classification of Headache Disorders, 3rd Edition (ICHD-3), as “other primary headache disorders.” This article provides clinicians with a distilled understanding of the diagnoses and their epidemiology, pathophysiology, and management.

RECENT FINDINGS
Cough-induced headache requires neuroimaging to exclude posterior fossa pathology and recently has been reported as a common symptom in patients with CSF-venous fistula. Clinical overlap is observed between patients with primary exercise headache and primary headache associated with sexual activity. Patients with recurrent thunderclap headache associated with sexual activity should be presumed to have reversible cerebral vasoconstriction syndrome until proven otherwise. De novo external-pressure headache is a common sequela among health care workers using personal protective equipment during the COVID-19 pandemic. New daily persistent headache is an important mimicker of chronic migraine or chronic tension-type headache and is distinguished by a daily-from-onset progression of persistent headache; a treatment-refractory course is often observed, and early involvement of a multidisciplinary team, including a psychotherapist, is advised.

SUMMARY
Patients with primary headache disorders that are classified as “other primary headache disorders” have presentations with unique diagnostic and management considerations. The disorders are highly recognizable, and an appreciation of the diagnoses will aid clinicians in providing safe and effective care for patients presenting with headache.
False Claims Act Overview and Implications for Neurologists
Authors: Rose Rachel V. , Kass Joseph S. 
Published: May 2021

ABSTRACT
The US Department of Health and Human Services Office of the Inspector General identifies the five most important federal fraud and abuse laws that are most applicable to physicians: the False Claims Act, the Anti-Kickback Statute, the Physician Self-Referral Law (Stark Law), the Exclusion Authorities, and the Civil Monetary Penalties Law
The False Claims Act is the US government’s primary tool for combating fraud perpetrated through the filing of false claims for federal government reimbursement. Neurologists and companies serving the needs of neurologic patients have not been immune from False Claims Act–related legal action. This article provides an overview of the False Claims Act, uses real-life neurologic cases to illustrate the range of False Claims Act violations and recoveries, and offers some practical compliance suggestions.
Pathophysiology of Migraine
Authors: Recober Ana 
Published: May 2021

ABSTRACT

PURPOSE OF REVIEW
This article summarizes the current understanding of the pathophysiology of migraine, including some controversial aspects of the underlying mechanisms of the disorder.

RECENT FINDINGS
Recent functional neuroimaging studies focusing on the nonpainful symptoms of migraine have identified key areas of the central nervous system implicated in the early phases of a migraine attack. Clinical studies of spontaneous and provoked migraine attacks, together with preclinical studies using translational animal models, have led to a better understanding of the disease and the development of disease-specific and targeted therapies.

SUMMARY
Our knowledge of the pathophysiology of migraine has advanced significantly in the past decades. Current evidence supports our understanding of migraine as a complex cyclical brain disorder that likely results from dysfunctional sensory processing and dysregulation of homeostatic mechanisms. This article reviews the underlying mechanisms of the clinical manifestations of each phase of the migraine cycle.
Headache in Children and Adolescents
Authors: Szperka Christina 
Published: May 2021

ABSTRACT

PURPOSE OF REVIEW
This article reviews the approach to a child or adolescent with headache, the criteria for common diagnoses, and the evidence base for treatments.

RECENT FINDINGS
The guidelines for acute and preventive treatment of migraine were updated in 2019. These guidelines summarize the available evidence and outline the questions that should be addressed in future research. The US Food and Drug Administration (FDA) approval of several new classes of drugs and devices to treat adult migraine in the past few years has resulted in ongoing or planned pediatric trials.

SUMMARY
Headache is a common symptom in children, and it is important to take a detailed history and perform a thorough physical examination to make the diagnosis. Nearly 1 in 10 children experience recurrent headaches due to migraine, which cause significant impairment in school performance and quality of life. The acute and preventive treatments that are currently available will help at least two-thirds of children with migraine, and several trials of new therapies offer hope for the future.
Leaning against the Wind and Crisis Risk
Authors: Schularick Moritz , Steege Lucas ter , Ward Felix 
Published: May 2021

Can central banks defuse rising stability risks in financial booms by leaning against the wind with higher interest rates? This paper studies the state-dependent effects of monetary policy on financial crisis risk. Based on the near-universe of advanced economy financial cycles since the nineteenth century, we show that discretionary leaning against the wind policies during credit and asset price booms are more likely to trigger crises than prevent them. (JEL E43, E44, E52, E58, F33)
Radiomics AI prediction for head and neck squamous cell carcinoma (HNSCC) prognosis and recurrence with target volume approach
Authors: FH Tang , CYW Chu , EYW Cheung 
Published: May 2021

Objectives:
To evaluate the performance of radiomics features extracted from planning target volume (PTV) and gross tumor volume (GTV) in the prediction of the death prognosis and cancer recurrence rate for head and neck squamous cell carcinoma (HNSCC).

Methods:
188 HNSCC patients’ planning CT images with radiotherapy structures sets were acquired from Cancer Imaging Archive (TCIA). The 3D slicer (v. 4.10.2) with the PyRadiomics extension (Computational Imaging and Bioinformatics Lab, Harvard medical School) was used to extract radiomics features from the radiotherapy planning images. An in-house developed deep learning artificial neural networks (DL-ANN) model was used to predict death prognosis and cancer recurrence rate based on the features extracted from GTV and PTV of the CT images.

Results:
The PTV radiomics features with DL-ANN model could achieve 77.7% accuracy with overall AUC equal to 0.934 and 0.932 when predicting HNSCC-related death prognosis and cancer recurrence respectively. Furthermore, the DL-ANN model can achieve an accuracy of 74.3% with AUC equal to 0.947 and 0.956 for the HNSCC-related death prognosis and cancer recurrence respectively using GTV features.

Conclusion:
Using both GTV and PTV radiomics features in the DL-ANN model, can aid in predicting HNSCC-related death prognosis and cancer recurrence. Clinicians may find it helpful in formulating different treatment regimens and facilitate personized medicine based on the predicted outcome when performing GTV and PTV delineation.

Advances in knowledge:
Radiomics features of GTV and PTV are reliable prognosis and recurrence predicting tools, which may help clinicians in GTV and PTV delineation to facilitate delivery of personalized treatment.
Frühmittelalterliche Grubenhäuser auf dem Basler Münsterhügel
Authors: Leuch-Bartels Katrin 
Published: May 2021

Der vorliegende Aufsatz stellt einen Auszug aus der Dissertation «Besiedlung des Basler Münsterhügels von der römischen Zeit bis 1000 n. Chr.» dar, die im April 2001 von der Philosophisch-historischen Fakultät der Universität Basel angenommen wurde.
Im Zentrum der Untersuchungen stehen die Grubenhäuser auf dem Basler Münsterhügel. Basierend auf den durch das Fundmaterial gewonnenen Datierungen wird die Bauweise der Grubenhäuser besprochen. Die während den Grabungen beobachteten Bestattungen werden katalogartig dargestellt und die Anhaltspunkte zur Datierung zusammengefasst. Als Fazit werden die durch die Auswertung der Grubenhäuser und ihres Umfeldes gewonnenen Kenntnisse in einen historischen Kontext gestellt.
Wohin mit dem Abfall?
Authors: Martinoli Danièle , Plüss Petra 
Published: May 2021

Der Inhalt einer spätrömischen Grube der Grabung 2004/38, Trafostation, Münsterplatz (A) 20, wurde archäobiologisch untersucht.
Bei den aus der Grube geborgenen Knochen handelt sich um diejenigen tierischen Abfälle, die beim Schlachten, beim Zerteilen des Tierkörpers in handliche Portionen und beim Entfleischen der Knochen anfielen.
Die botanischen Proben enthielten verkohlte Gerstenkörner in hoher Konzentration. Dies lässt auf einen verbrannten Gerstenvorrat oder auf Gerste, die beim Dörrprozess verkohlt ist, schliessen.
Zwei Tote und eine Hand voll Geld
Authors: Nick Michael 
Published: May 2021

Während der archäologischen Untersuchung an der Fabrikstrasse 40 stiessen die Ausgräber 1996 auf einen kleinen Metallklumpen. Während der Restaurierung zeigte sich, dass es sich beim Klumpen um mehrere zusammengebackene Potinmünzen handelt.
Von sechs Münzen sind jeweils so viele Bildelemente sichtbar, dass sie alle als Sequanerpotins der Gruppe A bestimmt werden können. Damit gehören die Münzen dem in der Gasfabrik Siedlung am häufigsten gefundenen Münztyp an.
Esskultur im Hinterhof
Authors: Häberle Simone , Matt Christoph Ph. , Vandorpe Patricia , Akeret Örni 
Published: May 2021

Das unterste Schichtpaket in der Latrinenverfüllung konnte ins 12. Jh. datiert werden und stellt den eigentlichen Benutzungshorizont der Latrine dar. Die interdisziplinäre Auswertung dieses Befundes umfasste die Aufarbeitung historischer Quellen sowie die Untersuchung der keramischen Funde, der Grosstierknochen und der Tier- und Pflanzenreste aus den Schlämmproben.
Anhand der Egebnisse wurde versucht, einen stadtgeschichtlichen und kulturhistorischen Kontext herzustellen und Aussagen zur Gesellschaftsschicht, zur «Esskultur» und zu handwerklichen Tätigkeiten (Hornverarbeitung) der Latrinenbenutzer zu formulieren.
How Do Peer Awards Motivate Creative Content? Experimental Evidence from Reddit
Authors: Burtch Gordon , He Qinglai , Hong Yili , Lee Dokyun 
Published: May 2021

We theorize peer awards’ effects on the volume and novelty of creative user-generated content (UGC) produced at online platform communities. We then test our hypotheses via a randomized field experiment on Reddit, wherein we randomly and anonymously assigned Reddit’s Gold Award to 905 users’ posts over a two-month period. We find that peer awards induced recipients to make longer, more frequent posts and that these effects were particularly pronounced among newer community members. Further, we show that recipients were causally influenced to engage in greater (lesser) exploitation (exploration) behavior, producing content that exhibited significantly greater textual similarity to their own past (awarded) content. However, because the effects were most pronounced among new community members, who also produce content that, in general, is systematically more novel than that of established members to begin with, this process yields a desirable outcome: larger volumes of generally novel UGC for the community. This paper was accepted by Chris Forman, information systems.
How Does Online Lending Influence Bankruptcy Filings?
Authors: Wang Hongchang , Overby Eric M. 
Published: May 2021

By providing quick and easy access to credit, online lending platforms may help borrowers overcome financial setbacks and/or refinance high-interest debt, thereby decreasing bankruptcy filings. On the other hand, these platforms may cause borrowers to overextend themselves financially, leading to a “debt trap” and increasing bankruptcy filings. To investigate the impact of online lending on bankruptcy filings, we leverage variation in when state regulators granted approval for a major online lending platform—Lending Club—to issue peer-to-peer loans. Using a difference-in-differences approach, we find that state approval of Lending Club led to an increase in bankruptcy filings. A complementary instrumental variables analysis using loan-level data yields similar results. We find suggestive evidence that the ease of receiving a Lending Club loan causes some borrowers to overextend themselves financially, leading to bankruptcy. Our results suggest that recent initiatives from online lending platforms to control how borrowers use loans, such as Lending Club’s “balance transfer loans” that send loan funds directly to creditors, can help these platforms provide safe and affordable credit. Our study adds to the literature that examines how online platforms influence society and the economy; it contributes to the literature that examines how financial products, services, and regulations influence bankruptcy filings; and it has policy implications for online lending design and regulation. This paper was accepted by Lorin Hitt, information systems.