bluuebunny/crossref_metadata_2025_split huggingface dataset:
An adaptive finite‐unit method for simulating frequency‐dependent responses of shallow foundations in layered soil under vertical dynamic loads
Authors: Shi Jun‐Yang , Chen Shi‐Shuenn , Kao Chi‐Jou , Chen Kuan‐Yu 
Published: October 2021

AbstractA number of simple models containing frequency‐independent elements have been presented to simulate unbounded soil in dynamic soil‐structure interaction problems. Most of the existing models were established through a traditional top‐down strategy with significant computational complexities. This study develops an alternative method based on a bottom‐up strategy, in which the optimal element layout is determined by an adaptive refinement procedure considering finite modularized units. This innovation eliminates the need for lengthy procedures to establish simple models. The proposed three‐parameter model is used to simulate the layered soil for rigid foundations undergoing vertical vibration. The accuracy of the model is validated by comparing the magnified responses obtained when a foundation is subjected to harmonic forces with those obtained via theoretical solutions and advanced numerical simulations. The proposed model is found to effectively simulate a layered half‐space and a soil layer on rock. Compared to two existing models, the proposed model performs better and has fewer parameters and a higher degree of adaptivity. Therefore, the adaptivity of simple models obtained using the proposed method may allow simulation of a variety of layered soil systems.
Barriers to cancer pain management from the perspective of patients: A qualitative study
Authors: Orujlu Samira , Hassankhani Hadi , Rahmani Azad , Sanaat Zohreh , Dadashzadeh Abbas , Allahbakhshian Atefeh 
Published: October 2021

AbstractAimThe aim of this study was to explore the barriers to effective pain management in Iranian people with cancer.DesignA qualitative descriptive design was used.MethodsThis qualitative descriptive study was performed on 14 people with cancer. Data were collected using semi‐structured interviews and analysed by Graneheim and Lundman's content analysis method.ResultsFour main categories emerged in relation to barriers to pain management from the perspective of people with cancer. Categories included 1) accepting and enduring divine pain, 2) negative attitudes towards the effectiveness of analgesics, 3) patients’ low knowledge of pain self‐management methods and 4) neglected pain management. Barriers to pain management are multidimensional in nature consisting of patients, healthcare providers and system components. Therefore, attempts should be focused on the education of patients and healthcare providers about pain management and eliminating the shortcomings of the healthcare system.
Highly Selective and Sensitive Aggregation‐Induced Emission of Fluorescein‐Coated Metal Oxide Nanoparticles
Authors: Shetty Suchetha , Baig Noorullah , Safa Muhieddine , Gharbi Ridha , Sriram Santhanagopalan , Rasoul Firas , Alameddine Bassam 
Published: October 2021

AbstractWe report the synthesis, characterization, and photophysical properties of novel metal oxide nanoparticles (NPs) coated with specially designed fluorescein substituents which are capped with electron‐withdrawing groups. The fluorescein‐coated nanoparticles were synthesized in excellent yields, and their structures were confirmed using various advanced spectroscopic, instrumental, and surface analysis techniques, revealing the formation of the target functionalized nanoparticles (FNPs) which show superior chemical and thermal stabilities. In addition, the photophysical properties of the FNPs were examined using UV‐visible absorption and fluorescence spectroscopy. These latter techniques disclosed aggregation‐induced emission (AIE) properties for most of the target FNPs, namely those which are soluble in common organic solvents at selective concentration ranges of water fractions in the solvent mixture.
MoS2‐Based Catalysts for N2 Electroreduction to NH3 – An Overview of MoS2 Optimization Strategies
Authors: Tian Liang , Zhao Jinxiu , Ren Xiang , Sun Xu , Wei Qin , Wu Dan 
Published: October 2021

AbstractThe nitrogen reduction reaction (NRR) has become an ideal alternative to the Haber‐Bosch process, as NRR possesses, among others, the advantage of operating under ambient conditions and saving energy consumption. The key to efficient NRR is to find a suitable electrocatalyst, which helps to break the strong N≡N bond and improves the reaction selectivity. Molybdenum disulfide (MoS2) as an emerging layered two‐dimensional material has attracted a mass of attention in various fields. In this minireview, we summarize the optimization strategies of MoS2‐based catalysts which have been developed to improve the weak NRR activity of primitive MoS2. Some theoretical predictions have also been summarized, which can provide direction for optimizing NRR activity of future MoS2‐based materials. Finally, an outlook about the optimization of MoS2‐based catalysts used in electrochemical N2 fixation are given.
Extrusion 3D printing of conjugated polymers
Authors: Chortos Alex 
Published: October 2021

AbstractConjugated polymers combine electronic charge transport properties with the ability to transport ions, enabling transduction between ionic and electronic currents. Many applications of conjugated polymers, such as biointerfaces, actuators, and energy storage, benefit from 3D structures. Among different methods for 3D fabrication, extrusion‐based 3D printing is a versatile approach that is compatible with multimaterial fabrication processes. This review summarizes progress in the emerging field of 3D printed conjugated polymers using three extrusion printing processes: direct ink write, meniscus‐guided printing, and electrohydrodynamic printing. Ink designs for direct in write are described in depth, including strategies for modifying the rheology and conductivity of the inks.
Anxiety and depression in colorectal cancer survivors: Are there differences by sexual orientation?
Authors: Boehmer Ulrike , Ozonoff Al , Winter Michael , Berklein Flora , Potter Jennifer , Ceballos Rachel M. , Clark Melissa A. 
Published: October 2021

AbstractObjectiveTo examine sexual minority compared to heterosexual survivors' health‐related anxiety, anxiety, and depression.MethodsFour hundred and eighty eligible survivors participated in a telephone survey, which measured their anxiety and depression. These survivors were diagnosed with stage I, II, or III colorectal cancer an average of three years prior to the survey and were recruited from four cancer registries. As explanatory factors, we considered individual, social and contextual characteristics, prior psychological factors, psychological responses to cancer, and characteristics of cancer and its treatments. Using forward selection with generalized linear models or logistic regression models, we identified significant correlates for each outcome.ResultsPrior to adjusting for covariates, depression was similar for all survivors, while sexual minority survivors had worse health‐related anxiety and anxiety compared to heterosexual survivors. After adjustment, these differences were no longer statistically significant. Individual, social and contextual characteristics, characteristics of cancer, and psychological responses to cancer explained 44% of the variance in anxiety and 60% of the variance in depression.ConclusionThere are modifiable factors associated with health‐related and generalized anxiety as well as depression that can be changed to improve cancer survivorship among diverse survivors.
Investigation of the chemical characteristics and anticancer effect of plasma‐activated water: The effect of liquid temperature
Authors: Pang Bolun , Liu Zhijie , Zhang Huaiyan , Wang Sitao , Gao Yuting , Xu Dehui , Liu Dingxin , Kong Michael G. 
Published: October 2021

AbstractThe liquid temperature during the preparation of plasma‐activated water (PAW) seriously affects the PAW chemical characteristics and its biological effect. In this study, four different temperatures (4°C, 25°C, 40°C, and 70°C) of deionized water are selected as variable parameters to investigate the effect on PAW. The results show that the physicochemical properties and the concentration of reactive oxygen and nitrogen species of PAW are significantly reduced when the temperatures are higher than 25°C; moreover, the above indexes are slightly decreased when the temperature is down to 4°C. Furthermore, by comparing the results of cell viability and apoptosis, it is found that the PAW of 25°C has a higher inactivation efficiency than other temperatures. Research on the temperature effect during PAW production is beneficial for tailoring the plasma–liquid system to enhance production efficiency.
An Ultrasensitive Virus ELISA Based on a magnetic Mesoporous Silica Nanoprobe
Authors: Ni Chang , Shen Yuanzhao , Li Zhenzhen , Yang Chih‐Tsung , Thierry Benjamin , Yang Bing , Zhou Xin 
Published: October 2021

AbstractDetection of infectious viruses relies on quantitative polymerase chain reaction (qPCR). However, qPCR requires costly equipment, a clean operating environment and experienced technicians, limiting its wide applicability. On the other hand, enzyme‐linked immunosorbent assay (ELISA) is widely used in biological laboratories due to its relatively high sensitivity and ease of operation. However, ELISA‐based detection of the virus is hampered because it is lower sensitive than qPCR. Herein, a nanoprobe ELISA (NP‐ELISA) based on a mesoporous silica nanoprobe, which is constructed by first being loaded with peroxidase and further coated with positively charged polymer polyethyleneimine, and finally functionalized with antivirus antibodies, is designed. Results show that each NP probe is encapsulating 170 peroxidase molecules and presents 200 antibody molecules on the surface. The limit of detection (LOD) of NP‐ELISA (LOD = 1450 PFU mL−1) for the detection of real virus samples is tenfold sensitive than that of standard ELISA (LOD = 14, 414 PFU mL−1) and the assay time for NP‐ELISA is reduced by 1 h as compared with standard one. Therefore, the NP‐ELISA provides a rapid and sensitive immunoassay platform that can readily be implemented for biological laboratory research as well as for on‐site clinical diagnostics.
Therapeutic effects of an oral gonadotropin‐releasing hormone receptor antagonist, relugolix, on preventing premature ovulation in mild ovarian stimulation for IVF
Authors: Nakao Kazuki , Kuroda Keiji , Horikawa Takashi , Moriyama Azusa , Juen Hiroyasu , Itakura Akiko , Watanabe Hideaki , Takamizawa Satoru , Ojiro Yuko , Nakagawa Koji , Sugiyama Rikikazu 
Published: October 2021

AbstractPurposeCan relugolix, a novel oral gonadotropin‐releasing hormone receptor (GnRH) antagonist, function as an alternative ovulation inhibitor to GnRH antagonist injections?MethodsThis single‐center, cross‐sectional retrospective study compared premature ovulation rates and clinical outcomes in IVF treatment after mild ovarian stimulation with 40 mg of relugolix (relugolix group) or 0.25‐mg injections of ganirelix acetate or cetrorelix acetate (injection group) between March 2019 and January 2020. Of 247 infertile women (256 IVF cycles) aged ≤42 years, 223 women (230 cycles) were evaluated. In the relugolix and injection groups, we compared 104 and 85 cycles after GnRH antagonist use before the LH surge (LH levels <10 mIU/ml) and 22 and 19 cycles during the LH surge (LH levels ≥10 mIU/ml), respectively.ResultsBefore the LH surge, the ovulation rates in the two groups were very low (p = 0.838), however; during the LH surge, the cycles using relugolix had a high ovulation rate of 40.9% compared with no ovulation in the injection group (p = 0.002). There were no significant differences in embryo culture findings and pregnancy outcomes between the two groups.ConclusionsAlthough relugolix had a high ovulation suppressive effect, when the LH surge occurred, its effect was insufficient.
Stabilization of the planar vertical take‐off and landing using nonlinear feedback control
Authors: Lozano Rogelio , Salazar Sergio , Flores Jonathan 
Published: October 2021

AbstractThis article presents a new control strategy for the well‐known problem of the planar vertical take‐off and landing. The total thrust is computed using a nonlinear feedback compensation so that the altitude reaches the desired altitude. The horizontal position x is then controlled by choosing the orientation angle as a smooth saturation function of x and . A proof of convergence is presented using a Lyapunov approach. The proposed control strategy is successfully tested in numerical simulations.
Root‐zone soil organic carbon enrichment is sensitive to land management across soil types and regions
Authors: Franzluebbers Alan J. 
Published: October 2021

AbstractMeasuring and monitoring changes in soil organic C (SOC) concentrations and stocks are important for understanding ecosystem functions. Sequestration of SOC has traditionally been measured from resource‐intensive studies over extended periods of time, but an alternative approach of calculating root‐zone SOC enrichment is described here as a proxy for estimating SOC sequestration using nonlinear distribution of SOC concentration in the surface 30 cm. From literature data across 52 studies, estimated SOC concentration at 30‐cm depth was not different between pairs of conservation management and conventional‐till cropland, suggesting support for the concept of using SOC concentration at 30‐cm depth as a baseline concentration from which enrichment can be calculated. Root‐zone SOC enrichment across this (n = 420) and an earlier study (n = 171) was 12.0 ± 0.6 Mg C ha–1 (mean ± SE) under conventional‐till cropland (n = 209), 16.1 ± 0.6 Mg C ha–1 under no‐till cropland (n = 269), 20.6 ± 1.0 Mg C ha–1 under grassland (n = 90), and 25.8 ± 3.8 Mg C ha–1 under woodland (n = 23). Regional climatic conditions and soil texture were important in influencing baseline SOC storage and total SOC stock but were minor factors in affecting root‐zone SOC enrichment with conservation management. Root‐zone SOC enrichment is a relatively simple and straightforward calculation method to indicate SOC sequestration, and if deployed across a diversity of management and farm locations, could lead to better SOC stock inventories and analyses of how contemporary management influences SOC stock change in different ecoregions.
Data‐drivensparse partial least squares
Authors: Lorenzo Hadrien , Cloarec Olivier , Thiébaut Rodolphe , Saracco Jérôme 
Published: October 2021

AbstractIn the supervised high dimensional settings with a large number of variables and a low number of individuals, variable selection allows a simpler interpretation and more reliable predictions. That subspace selection is often managed with supervised tools when the real question is motivated by variable prediction. We propose a partial least square (PLS) based method, called data‐driven sparse PLS (ddsPLS), allowing variable selection both in the covariate and the response parts using a single hyperparameter per component. The subspace estimation is also performed by tuning a number of underlying parameters. The ddsPLS method is compared with existing methods such as classical PLS and two well established sparse PLS methods through numerical simulations. The observed results are promising both in terms of variable selection and prediction performance. This methodology is based on new prediction quality descriptors associated with the classicaland, and uses bootstrap sampling to tune parameters and select an optimal regression model.
Evolution, trends and future research lines in corporate social responsibility and tourism: A bibliometric analysis and science mapping
Authors: Sánchez‐Camacho Carlos , Carranza Rocío , Martín‐Consuegra David , Díaz Estrella 
Published: October 2021

AbstractCorporate social responsibility (CSR) has become a topic of growing interest in countless areas, and the number of studies focused on researching different CSR aspects is increasing. Nevertheless, this type of research within the tourism sector is less developed compared to other fields. Consequently, a significant research opportunity in the tourism industry has been detected. Therefore, this study uses the SciMAT software to analyze 1800 articles published on CSR within the tourism field through the co‐word analysis technique. Findings led to conclude that the entire scientific production within this field is composed of eight major thematic areas: (1) Business activity‐financial performance, (2) Attitude and behaviour, (3) Marketing perspective, (4) Sustainable tourism, (5) Sustainability, (6) Governmental action, (7) Environmental awareness and motivation and (8) Impact of major events. Additionally, interpretation of the main findings of the bibliometric analysis and implications for future trends of CSR in the tourism field has been discussed.
Optimized Methodology for the Calculation of Electrostriction from First‐Principles
Authors: Tanner Daniel S. P. , Bousquet Eric , Janolin Pierre‐Eymeric 
Published: October 2021

AbstractIn this work a new method for the calculation of the electrostrictive properties of materials using density functional theory is presented. The method relies on the thermodynamical equivalence, in a dielectric, of the quadratic mechanical responses (stress or strain) to applied electric stimulus (electric or polarization fields) to the strain or stress dependence of its dielectric susceptibility or stiffness tensors. Comparing with current finite‐field methodologies for the calculation of electrostriction, it is demonstrated that this presented methodology offers significant advantages of efficiency, robustness, and ease of use. These advantages render tractable the high throughput theoretical investigation into the largely unknown electrostrictive properties of materials, and the microscopic origins of giant electrostriction.
Communication and culture: A multispecies endeavour within a shared habitat
Authors: McIntyre‐Mills Janet J. 
Published: October 2021

AbstractCOVID‐19 can be seen as feedback for anthropocentric social, economic and environmental decision‐making that disrespects other living systems. The paper makes a case that respects for multiple species, and the onus of beneficence should be applied to all living systems of which we are a strand. Human beings are not exceptional insofar as they are able to communicate, make decisions, demonstrate a sense of community and show empathy or to make political calculations. What does this mean for the way we live our lives? Respect for persons needs to include animals, plants and the earth. It is time to rethink rights and responsibilities to protect habitat. Goodall stresses that the loss of habitat leads to species that have never been in contact before (and thus without any resistance) causing cross species infections.
Engineering extracellular vesicles for Alzheimer's disease: An emerging cell‐free approach for earlier diagnosis and treatment
Authors: Lazar Sabrina Valentina , Mor Sirjan , Wang David , Goldbloom‐Helzner Leora , Clark Kaitlin , Hao Dake , Farmer Diana Lee , Wang Aijun 
Published: October 2021

AbstractAlzheimer's disease (AD) is a debilitating neurodegenerative disorder affecting over five million people globally and has no established cure. Current AD‐related treatments only alleviate cognitive and behavioral symptoms and do not address disease onset or progression, underlining the unmet need to create an effective, innovative AD therapeutic. Extracellular vesicles (EVs) have emerged as a new class of nanotherapeutics. These secreted, lipid‐bound cellular signaling carriers show promise for potential clinical applications for neurodegenerative diseases like AD. Additionally, analyzing contents and characteristics of patient‐derived EVs may address the unmet need for earlier AD diagnostic techniques, informing physicians of altered genetic expression or cellular communications specific to healthy and diseased physiological states. There are numerous recent advances in regenerative medicine using EVs and include bioengineering perspectives to modify EVs, target glial cells in neurodegenerative diseases like AD, and potentially use EVs to diagnose and treat AD earlier.This article is categorized under:
Neurological Diseases > Biomedical Engineering
Neurological Diseases > Molecular and Cellular Physiology
Neurological Diseases > Stem Cells and Development
The role of leadership education in Native nation building at tribal colleges and universities
Authors: Youngbull Natalie Rose 
Published: October 2021

AbstractThis article explores how leadership education and program development is centered on the needs of students, local tribal communities, and institutional charter within the Tribal College and University (TCU) context. Two leadership‐based academic programs at two respective TCUs are discussed through the lens of a culturally appropriate framework of Native‐nation building to illustrate how leadership development at TCUs is focused on developing student leaders within and for tribal communities.
Digital wormholes
Authors: O’Neill Elizabeth 
Published: October 2021

AbstractCameras, microphones, and other sensors continue to proliferate in the world around us. I offer a new metaphor for conceptualizing these technologies: they are digital wormholes, transmitting representations of human persons between disparate points in space–time. We frequently cannot tell when they are operational, what kinds of data they are collecting, where the data may reappear in the future, and how the data can be used against us. The wormhole metaphor makes the mysteriousness of digital sensors salient: digital sensors have brought us to a strange place. If humans are to be capable of making sensible decisions while under observation by digital sensors, we must improve the epistemic position of potential sensor subjects.