bluuebunny/crossref_metadata_2025_split huggingface dataset:
Active antibacterial coating of cotton fabrics with antimicrobial proteins
Authors: Xu Amy Y. , McGillivray Duncan J. , Dingley Andrew J. 
Published: June 2021

AbstractThe prevention of bacteria colonization by immobilizing proteins with antimicrobial activity onto cotton fabrics was investigated. Such coatings have potential applications in medical dressing materials used in wound care and healing. Two antimicrobial proteins lysozyme and hydramacin-1 (HM-1) were surface immobilized through two linkers (3-aminopropyl) triethoxysilane (APTES) and citric acid in the presence of the water soluble carbodiimide coupling reagent 1-cyclohexyl-3-(2-morpholinoethyl)carbodiimide metho-p-toluenesulfonate. Surface composition analysis by attenuated total reflection-Fourier transform infrared and X-ray photoelectron spectroscopies confirmed formation of the protein-cellulose conjugates. Antimicrobial activities of the different functionalized surfaces were found to vary between APTES and citric acid directed coatings. Citric acid immobilized lysozyme treated samples demonstrated superior activity against Gram-positive Bacillus subtilis, whereas APTES immobilized HM-1 treated samples demonstrated an advantage in inhibiting the growth of Gram-negative Escherichia coli. The antibacterial activity and stability of citric acid immobilized protein fabrics following sonication, boiling and chemical treatment were noticeably higher than that of the corresponding APTES immobilized protein fabrics. The dual coating of fibers with both antimicrobial proteins afforded efficient antimicrobial activities against both bacterial species. The results suggest that coating cotton fibers with antimicrobial proteins and peptides represents a feasible approach for developing active surfaces that prohibit growth and colonization of bacterial strains and can be potentially used in medical cotton-based fabrics.
Tensions in Representing Behavioral Data in an Electronic Health Record
Authors: Marcu Gabriela , Dey Anind K. , Kiesler Sara 
Published: June 2021

AbstractTaking an action research approach, we engaged in fieldwork with school-based behavioral health care teams to: observe record keeping practices, design and deploy a prototype system addressing key challenges, and reflect on its use. We describe the challenges of capturing behavioral data using both paper and electronic records. Creating records of behaviors requires direct observation, and as a result the record keeping responsibility is challenging to distribute across a care team. Behavioral data on paper must be transferred and prepared for reporting, both inside the organization and to stakeholders outside of the organization. In prototyping a computerized working record, we targeted user needs for capturing details of a behavioral incident in the moment. Challenges persisted through the transition from paper to our prototype, and based on these empirical findings over two years of fieldwork, we present five tensions in representing behavioral data in an electronic health record. These tensions reflect the differences between entering behavioral data into the record for intraorganizational use versus interorganizational use.
Apatinib with doxorubicin and ifosfamide as neoadjuvant therapy for high-risk soft tissue sarcomas: a retrospective cohort study
Authors: Tian Zhichao , Wang Jiaqiang , Yang Jinpo , Zhang Peng , Wang Xin , Zhang Fan , Li Po , Yao Weitao 
Published: June 2021

Summary

Background

There is a need to establish an effective neoadjuvant therapy for soft tissue sarcomas (STSs). We previously showed that apatinib, administered in combination with doxorubicin-based chemotherapy, improves the efficacy of treatment. This study aimed to clarify the effectiveness and safety of apatinib combined with doxorubicin and ifosfamide (AI) neoadjuvant chemotherapy for STSs.

Methods

This retrospective study included patients with STS who received neoadjuvant therapy and surgery between January 2016 and January 2019. The patients were divided into two treatment groups: AI + apatinib group and AI group (doxorubicin + ifosfamide).

Results

The study included 74 patients (AI + apatinib: 26, AI: 48) with STS. There were significant between-group differences in objective response rates (53.85% vs. 29.17%, p = 0.047) and the average change in target lesion size from baseline (-40.46 ± 40.30 vs. -16.31 ± 34.32, p = 0.008). The R0 rate (84.62% vs. 68.75%; p = 0.170) and 2-year disease-free survival (73.08% vs. 62.50%, p = 0.343) were similar across groups. Finally, the rates of neoadjuvant therapy-related adverse effects and postoperative complications were similar in both groups (p > 0.05).

Conclusion

Apatinib plus doxorubicin and ifosfamide regimen is safe and effective as neoadjuvant therapy for patients with STS. However, the significantly improved preoperative ORR observed after neoadjuvant therapy did not translate into a significantly improved R0 rate and 2-year DFS. Prospective, well-powered studies are warranted to determine the long-term efficacy and optimal application of these protocols.
Introducing pre-impact air-cushioning effects into the Wagner model of impact theory
Authors: Moore Madeleine R. 
Published: June 2021

AbstractIn this analysis, we consider the effects of non-quiescent initial conditions driven by pre-impact air–water interactions on the classical Wagner model of impact theory. We consider the problem of a rigid, solid impactor moving vertically towards a liquid pool. Prior to impact, viscous forces in the air act to deform the liquid free surface, inducing a flow in the pool. These interactions are then incorporated as initial conditions in the post-impact analysis. We derive expressions for the size of the effective contact set, the leading-order pressure and force on the impactor, and the speed and thickness of the jet at its base. In all cases, we show that the effect of the pre-impact behaviour is to cushion the impactor, reducing the size of the effective contact set and, hence, the force on the impactor. Small- and large-time asymptotic solutions are derived for general power-law impactors, and we show that the effects of the air die away as the impact progresses, so that we approach the classical Wagner solution.
Voluntary redistribution mechanism in asymmetric coordination games
Authors: Aoyagi Masaki , Nishimura Naoko , Okano Yoshitaka 
Published: June 2021

AbstractAn inequality game is an asymmetric 2 × 2 coordination game in which player 1 earns a substantially higher payoff than player 2 except in the inefficient Nash equilibrium (NE). The two players may have either common or conflicting interests over the two NE. This paper studies a redistribution scheme which allows the players to voluntarily transfer their payoffs after the play of an inequality game. We find that the redistribution scheme induces positive transfer from player 1 to player 2 in both common- and conflicting- interest games, and is particularly effective in increasing efficient coordination and reducing coordination failures in conflicting-interest games. We explain these findings by considering reciprocity by player 1 in response to the sacrifice made by player 2 in achieving efficient coordination in conflicting-interest games.
Understanding the origin of the positron annihilation line and the physics of supernova explosions
Authors: Frontera F. , Virgilli E. , Guidorzi C. , Rosati P. , Diehl R. , Siegert T. , Fryer C. , Amati L. , Auricchio N. , Campana R. , Caroli E. , Fuschino F. , Labanti C. , Orlandini M. , Pian E. , Stephen J. B. , Del Sordo S. , Budtz-Jorgensen C. , Kuvvetli I. , Brandt S. , da Silva R. M. Curado , Laurent P. , Bozzo E. , Mazzali P. , Valle M. Della 
Published: June 2021

AbstractNuclear astrophysics, and particularly nuclear emission line diagnostics from a variety of cosmic sites, has remained one of the least developed fields in experimental astronomy, despite its central role in addressing a number of outstanding questions in modern astrophysics. Radioactive isotopes are co-produced with stable isotopes in the fusion reactions of nucleosynthesis in supernova explosions and other violent events, such as neutron star mergers. The origin of the 511 keV positron annihilation line observed in the direction of the Galactic Center is a 50-year-long mystery. In fact, we still do not understand whether its diffuse large-scale emission is entirely due to a population of discrete sources, which are unresolved with current poor angular resolution instruments at these energies, or whether dark matter annihilation could contribute to it. From the results obtained in the pioneering decades of this experimentally-challenging window, it has become clear that some of the most pressing issues in high-energy astrophysics and astro-particle physics would greatly benefit from significant progress in the observational capabilities in the keV-to-MeV energy band. Current instrumentation is in fact not sensitive enough to detect radioactive and annihilation lines from a wide variety of phenomena in our and nearby galaxies, let alone study the spatial distribution of their emission. In this White Paper (WP), we discuss how unprecedented studies in this field will become possible with a new low-energy gamma-ray space experiment, called ASTENA (Advanced Surveyor of Transient Events and Nuclear Astrophysics), which combines new imaging, spectroscopic and polarization capabilities. In a separate WP (Guidorzi et al. 39), we discuss how the same mission concept will enable new groundbreaking studies of the physics of Gamma–Ray Bursts and other high-energy transient phenomena over the next decades.
Analytical corrections for double-cantilever beam tests
Authors: Chen T. , Harvey C. M. , Wang S. , Silberschmidt V. V. 
Published: June 2021

AbstractDouble-cantilever beams (DCBs) are widely used to study mode-I fracture behavior and to measure mode-I fracture toughness under quasi-static loads. Recently, the authors have developed analytical solutions for DCBs under dynamic loads with consideration of structural vibration and wave propagation. There are two methods of beam-theory-based data reduction to determine the energy release rate: (i) using an effective built-in boundary condition at the crack tip, and (ii) employing an elastic foundation to model the uncracked interface of the DCB. In this letter, analytical corrections for a crack-tip rotation of DCBs under quasi-static and dynamic loads are presented, afforded by combining both these data-reduction methods and the authors’ recent analytical solutions for each. Convenient and easy-to-use analytical corrections for DCB tests are obtained, which avoid the complexity and difficulty of the elastic foundation approach, and the need for multiple experimental measurements of DCB compliance and crack length. The corrections are, to the best of the authors’ knowledge, completely new. Verification cases based on numerical simulation are presented to demonstrate the utility of the corrections.
Recalled Positive Influences within Life-Story Interviews and Self-Reported Generative Concern in German Older Adults: The Moderating Role of Extraversion
Authors: Busch Holger , Hofer Jan 
Published: June 2021

AbstractPrevious research has shown that recalling positive influences in one’s life story correlates with generative concern. Given findings that not everyone benefits from generative efforts uniformly, however, the present study tested if extraversion moderates this relation. In total, 147 older German adults (59 through 83 years) recalled positive influences in their lives in an interview session and provided self-report questionnaire data on their generative concern (Loyola Generativity Scale), generative behavior (Generative Behavior Checklist), and extraversion (Mini-IPIP scales). Results from a moderated mediation model indicate that recalled positive influences related to generative concern but not generative behavior. Moreover, extraversion did indeed moderate between recalled positive influences and generative concern in that the relation was significantly positive for medium and high extraversion. The findings suggest that what people learn from generative role models is generative concern rather than generative behavior. They also suggest a twofold role of extraversion for generativity: It has been found to be a predictor of generativity but also affects what people gain from others’ generative efforts.
Producing landscapes of environmental justice: exploitation of woodlands and wetlands and deep historical geographies of justice on Gotland
Authors: Mels Tom 
Published: June 2021

Abstract
Context
The importance of justice is increasingly recognized in environmental policy making. Research on environmental justice offers an important perspective on landscape transformations, both natural and social.

Objectives
This paper asks how current work on environmental justice might contribute to the development of socio-environmental knowledge of the biophysical landscape. The paper explores the relations between environmental justice thinking and the production of a distinctively capitalist landscape.

Methods
The paper builds on a review of environmental justice and landscape literature and, for the empirical part, on archival studies and secondary sources.

Results
The paper shows that there remains a disjunction between landscape studies and the environmental justice literature. It provides a theoretically informed approach of bringing together environmental justice scholarship with the transformations of a contested and distinctively capitalist landscape. By studying changes in woodlands and wetlands on the island of Gotland, Sweden, it uncovers a process of the production of landscape that elicits “deep” historical geographies of environmental justice. The massive exploitation of wetlands and forests shows how an approach encompassing environmental justice in conjunction with forms of resource exploitation and conservation can help grasp changes in the landscape.
Society as Cause and Cure: The Norms of Transgender Social Medicine
Authors: Slagstad Ketil 
Published: June 2021

AbstractThis article analyzes how trans health was negotiated on the margins of psychiatry from the late 1970s and early 1980s. In this period, a new model of medical transition was established for trans people in Norway. Psychiatrists and other medical doctors as well as psychologists and social workers with a special interest and training in social medicine created a new diagnostic and therapeutic regime in which the social aspects of transitioning took center stage. The article situates this regime in a long Norwegian tradition of social medicine, including the important political role of social medicine in the creation of the postwar welfare state and its scope of addressing and changing the societal structures involved in disease. By using archival material, medical records and oral history interviews with former patients and health professionals, I demonstrate how social aspects not only underpinned diagnostic evaluations but were an integral component of the entire therapeutic regime. Sex reassignment became an integrative way of imagining and practicing psychiatry as social medicine. The article specifically unpacks the social element of these diagnostic and therapeutic approaches in trans medicine. Because the locus of intervention and treatment remained the individual, an approach with subversive potential ended up reproducing the norms that caused illness in the first place: “the social” became a conformist tool to help the patient integrate, adjust to and transform the pathology-producing forces of society.
Necessity or opportunity? Government size, tax policy, corruption, and implications for entrepreneurship
Authors: Audretsch David B. , Belitski Maksim , Chowdhury Farzana , Desai Sameeksha 
Published: June 2021

Abstract
Government size, corruption, and tax policy can influence allocation towards necessity or opportunity-driven entrepreneurship. Using a comparative multi-source sample across 52 countries during 2005–2015, we apply a mixed-process estimation of the simultaneously unrelated system of equations and unpack these heterogeneous and complex effects. Interestingly, our results show that the influence of tax policy and corruption on necessity and opportunity entrepreneurship depends on government size. Our results hold for numerous robustness analyses.

Plain English summary
Institutions matter for the choice of opportunity and necessity-driven entrepreneurship. Government size, the level of corruption, and tax policy directly affect entrepreneurs’ motivation and incentives. We study 52 countries during 2005–2015 to find out to what extent tax rate, corruption, and a range of government expenditure change the allocation of necessity and opportunity entrepreneurship. Our main implications are for (1) Research: Formal and informal institutions need to be considered when studying entrepreneurship allocation, particularly in an emerging and developing country context. Results suggest that the impact of the same institutional settings and informal institutions such as corruption on necessity and opportunity entrepreneurship is not uniform in size and scope and have different magnitude. The effect of government expenditure on necessity and opportunity entrepreneurship is not ubiquitous. (2) Management: The broader institutional context affects allocation of entrepreneurship, and potential entrepreneurs can consider how corruption in particular can affect them. (3) Policy: Policymakerscan measure the extent to which opportunity and necessity entrepreneurship are likely to change, when they make changes to tax policy, resources for public spending, and take anti-corruption measures.
Structurally Driven Environmental Degradation of Friction in MoS2 Films
Authors: Curry John F. , Ohta Taisuke , DelRio Frank W. , Mantos Philip , R. Jones Morgan , F. Babuska Tomas , Bobbitt N. Scott , Argibay Nicolas , A. Krick Brandon , Dugger Michael T. , Chandross Michael 
Published: June 2021

AbstractWe report an investigation of the friction mechanisms of MoS2 thin films under changing environments and contact conditions using a variety of computational and experimental techniques. Molecular dynamics simulations were used to study the effects of water and molecular oxygen on friction and bonding of MoS2 lamellae during initial sliding. Characterization via photoelectron emission microscopy (PEEM) and Kelvin probe force microscopy (KPFM) were used to determine work function changes in shear modified material within the top few nanometers of MoS2 wear scars. The work function was shown to change with contact conditions and environment, and shown by density functional theory (DFT) calculations and literature reports to be correlated with lamellae size and thickness of the basally oriented surface layer. Results from nanoscale simulations and macroscale experiments suggest that the evolution of the friction behavior of MoS2 is linked primarily to the formation or inhibition of a basally oriented, molecularly thin surface film with long-range order.
Factors promoting shared decision-making in renal replacement therapy for patients with end-stage kidney disease: systematic review and qualitative meta-synthesis
Authors: Shi Yu , Li Wang , Duan Fangjian , Pu Shi , Peng Hongmei , Ha Mei , Luo Yu 
Published: June 2021

Abstract
Purpose
Shared decision-making (SDM) about the type of renal replacement therapy to use is a matter of great importance involving patients, their families, and health treatment teams. This review aims to synthesize the volume of qualitative work explaining the factors influencing SDM regarding renal replacement therapy.

Methods
A systematic review and qualitative meta-synthesis approach recommended by JBI was used, six databases were searched. Studies were qualitative or mixed research published since 2000, with a primary focus on patient experiences, perceptions and practices regarding which method to choose for renal replacement therapy in End-Stage Kidney Disease (ESKD) patients. All themes were analyzed and compared to the established connectedness.

Results
A total of 1313 patients were enrolled in 32 studies focusing on factors associated with SDM regarding renal replacement therapy were included. All quality evaluations of the literature were medium to high. Four common themes were identified in our synthesis: (1) patient personal reasons, (2) family-related factors, (3) health care professional-related factors, and (4) social factors influence.

Conclusion
The model proposes pathways that could be explored further in future qualitative and quantitative studies and suggests that patients’ beliefs, emotions, and awareness should be targeted alongside patients’ decision-making practices to increase the efficacy of interventions. The majority of studies included in this review focus on older patients, and all report patients’ perspectives. Further research is required to understand the family member perspectives on SMD of renal replacement therapy.
Genetic characterisation of the influenza viruses circulating in Bulgaria during the 2019–2020 winter season
Authors: Korsun Neli , Trifonova Ivelina , Voleva Silvia , Grigorova Iliyana , Angelova Svetla 
Published: June 2021

AbstractInfluenza viruses have a high potential for genetic changes. The objectives of this study were to analyse influenza virus circulation in Bulgaria during the 2019/2020 season, to perform a phylogenetic and molecular analyses of the haemagglutinin (HA) and neuraminidase (NA) sequences of representative influenza strains, and to identify amino acid substitutions compared to the current vaccine strains. Seasonal influenza viruses A(H3N2), A(H1N1)pdm09 and B/Victoria-lineage were detected using a real-time RT-PCR in 323 (23.3%), 149 (10.7%) and 138 (9.9%) out of 1387 patient samples studied, respectively. The HA genes of A(H3N2) viruses analysed belonged to clades 3C.3a (21 strains) and 3C.2a (5 strains): subclades 3C.2a1b + T131K, 3C.2a1b + T135K-B and 3C.2a1b + T135K-A. The clade 3C.3a and subclade 3C.2a1b viruses carried 5 and 14–17 substitutions in HA, as well as 3 and 9 substitutions in NA, respectively, in comparison with the A/Kansas/14/2017 vaccine virus, including some substitutions in the HA antigenic sites A, B, C and E. All 21 A(H1N1)pdm09 viruses sequenced fell into 6B.1A5A subclade. Amino acid sequence analysis revealed the presence of 7–11 substitutions in HA, compared to the A/Brisbane/02/2018 vaccine virus, three of which occurred in antigenic site Sb, along with 6–9 changes at positions in NA. All 10 B/Victoria-lineage viruses sequenced belonged to clade 1A with a triple deletion in HA1 (genetic group 1A(Δ3)B) and carried 7 and 3 substitutions in HA and NA, respectively, with respect to the B/Colorado/06/2017 vaccine virus. The results of this study confirm the rapid evolution of influenza viruses and the need for continuous antigenic and genetic surveillance.
Kontingente Bauchgefühle
Authors: Rund Mario 
Published: June 2021

ZusammenfassungPraktiken des Entscheidens und Urteilens sind mit Subjektverhältnissen verknüpft. Für die Forschung sind daher für Subjektivierungsprozesse relevante Kontexte und Einflüsse zu fokussieren. Hinsichtlich der Sozialraumarbeit gehören hierzu bestimmte Anrufungen und Rationalitäten, die über verschiedene Programme mit Bezug zu Gemeinwesen, Sozialraum und Raum transportiert werden.