bluuebunny/crossref_metadata_2025_split huggingface dataset:
Theory, Observation, and Ultrafast Response of the Hybrid Anapole Regime in Light Scattering
Authors: Canós Valero Adrià , Gurvitz Egor A. , Benimetskiy Fedor A. , Pidgayko Dmitry A. , Samusev Anton , Evlyukhin Andrey B. , Bobrovs Vjaceslavs , Redka Dmitrii , Tribelsky Michael I. , Rahmani Mohsen , Kamali Khosro Zangeneh , Pavlov Alexander A. , Miroshnichenko Andrey E. , Shalin Alexander S. 
Published: August 2021

AbstractModern nanophotonics has witnessed the rise of “electric anapoles” (EDAs), destructive interferences of electric and toroidal electric dipoles, actively exploited to resonantly decrease radiation from nanoresonators. However, the inherent duality in Maxwell equations suggests the intriguing possibility of “magnetic anapoles,” involving a nonradiating composition of a magnetic dipole and a magnetic toroidal dipole. Here, a hybrid anapole (HA) of mixed electric and magnetic character is predicted and observed experimentally via dark field spectroscopy, with all the dominant multipoles being suppressed by the toroidal terms in a nanocylinder. Breaking the spherical symmetry allows to overlap up to four anapoles stemming from different multipoles with just two tuning parameters. This effect is due to a symmetry‐allowed connection between the resonator multipolar response and its eigenstates. The authors delve into the physics of such current configurations in the stationary and transient regimes and explore new ultrafast phenomena arising at sub‐picosecond timescales, associated with the HA dynamics. The theoretical results allow the design of non‐Huygens metasurfaces featuring a dual functionality: perfect transparency in the stationary regime and controllable ultrashort pulse beatings in the transient. Besides offering significant advantages with respect to EDAs, HAs can play an essential role in developing the emerging field of ultrafast resonant phenomena.
Facile Repair of Anti‐Corrosion Polymeric Composite Coatings Based on Light Triggered Self‐Healing
Authors: Ma Yue , Yang Yuman , Cao Daruo , Fang Jun , Zhu Cheng , Yang Meng , Fang Liang , Lu Chunhua , Xu Zhongzi 
Published: August 2021

AbstractPhotothermally induced self‐healing coatings are widely reported, while their application scenarios are rarely taken with concern. In addition, there is a need to achieve the balance between good properties and self‐healing behaviors for closing the gap between academic research and engineering applications. Here, self‐healing composite coatings are designed based on silane‐modified epoxy chains with reversible crosslinking points and multifunctional fillers of cerium oxide nanoparticles grown on graphene nanosheets, and their applications are demonstrated for restricted regions. Diglycidyl ether‐terminated poly(dimethylsiloxane) is co‐polymerized with diglycidylether of bisphenol A with the weight ratio of 1/99–10/90 to achieve surface‐tension driven crack closure, while dangling furan groups contribute to reversible crosslinking points via Diels–Alder reaction. Cerium oxide nanoparticles and graphene nanosheets enhance anti‐corrosion properties, and graphene nanosheets also act as photothermal fillers. The results show that pencil hardness, polarized resistance, and coating resistance are highly improved via the introduction of multifunctional fillers at 1 and 2 phr. Good thermally and photothermally induced self‐healing is demonstrated. This work provides a new application thought for light triggered self‐healing coatings that can be used for restricted regions including inner walls of pipelines and reactors.
Transcranial Magnetic Stimulation Exerts “Rejuvenation” Effects on Corticostriatal Synapses after Partial Dopamine Depletion
Authors: Natale Giuseppina , Pignataro Annabella , Marino Gioia , Campanelli Federica , Calabrese Valeria , Cardinale Antonella , Pelucchi Silvia , Marcello Elena , Gardoni Fabrizio , Viscomi Maria Teresa , Picconi Barbara , Ammassari‐Teule Martine , Calabresi Paolo , Ghiglieri Veronica 
Published: August 2021

AbstractBackgroundIn experimental models of Parkinson's disease (PD), different degrees of degeneration to the nigrostriatal pathway produce distinct profiles of synaptic alterations that depend on progressive changes in N‐methyl‐D‐aspartate receptors (NMDAR)‐mediated functions. Repetitive transcranial magnetic stimulation (rTMS) induces modifications in glutamatergic and dopaminergic systems, suggesting that it may have an impact on glutamatergic synapses modulated by dopamine neurotransmission. However, no studies have so far explored the mechanisms of rTMS effects at early stages of PD.ObjectivesWe tested the hypothesis that in vivo application of rTMS with intermittent theta‐burst stimulation (iTBS) pattern alleviates corticostriatal dysfunctions by modulating NMDAR‐dependent plasticity in a rat model of early parkinsonism.MethodsDorsolateral striatal spiny projection neurons (SPNs) activity was studied through ex vivo whole‐cell patch‐clamp recordings in corticostriatal slices obtained from 6‐hydroxydopamine‐lesioned rats, subjected to a single session (acute) of iTBS and tested for forelimb akinesia with the stepping test. Immunohistochemical analyses were performed to analyze morphological correlates of plasticity in SPNs.ResultsAcute iTBS ameliorated limb akinesia and rescued corticostriatal long‐term potentiation (LTP) in SPNs of partially lesioned rats. This effect was abolished by applying a selective inhibitor of GluN2B‐subunit‐containing NMDAR, suggesting that iTBS treatment could be associated with an enhanced activation of specific NMDAR subunits, which are major regulators of structural plasticity during synapse development. Morphological analyses of SPNs revealed that iTBS treatment reverted dendritic spine loss inducing a prevalence of thin‐elongated spines in the biocytin‐filled SPNs.ConclusionsTaken together, our data identify that an acute iTBS treatment produces a series of plastic changes underlying striatal compensatory adaptation in the parkinsonian basal ganglia circuit. © 2021 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society
Scale‐ and Slice‐aware Net (S2aNet) for 3D segmentation of organs and musculoskeletal structures in pelvic MRI
Authors: Yan Chaoyang , Lu Jing‐Jing , Chen Kang , Wang Lei , Lu Haoda , Yu Li , Sun Mengyan , Xu Jun 
Published: August 2021

PurposeMRI of organs and musculoskeletal structures in the female pelvis presents a unique display of pelvic anatomy. Automated segmentation of pelvic structures plays an important role in personalized diagnosis and treatment on pelvic structures disease. Pelvic organ systems are very complicated, and it is a challenging task for 3D segmentation of massive pelvic structures on MRI.MethodsA new Scale‐ and Slice‐aware Net (aNet) is presented for 3D dense segmentation of 54 organs and musculoskeletal structures in female pelvic MR images. A Scale‐aware module is designed to capture the spatial and semantic information of different‐scale structures. A Slice‐aware module is introduced to model similar spatial relationships of consecutive slices in 3D data. Moreover, aNet leverages a weight‐adaptive loss optimization strategy to reinforce the supervision with more discriminative capability on hard samples and categories.ResultsExperiments have been performed on a pelvic MRI cohort of 27 MR images from 27 patient cases. Across the cohort and 54 categories of organs and musculoskeletal structures manually delineated, aNet was shown to outperform the UNet framework and other state‐of‐the‐art fully convolutional networks in terms of sensitivity, Dice similarity coefficient and relative volume difference.ConclusionThe experimental results on the pelvic 3D MR dataset show that the proposed aNet achieves excellent segmentation results compared to other state‐of‐the‐art models. To our knowledge, aNet is the first model to achieve 3D dense segmentation for 54 musculoskeletal structures on pelvic MRI, which will be leveraged to the clinical application under the support of more cases in the future.
Clinically feasible diffusion MRI in muscle: Time dependence and initial findings in Duchenne muscular dystrophy
Authors: McDowell Amy R. , Feiweier Thorsten , Muntoni Francesco , Hall Matt G. , Clark Chris A. 
Published: August 2021

PurposeTo characterize the diffusion time‐dependence in muscle in healthy adult volunteers, boys with Duchenne’s muscular dystrophy (DMD), and age‐matched controls in a clinically feasible acquisition time for pediatric applications.MethodsDiffusion data were acquired using a pulsed gradient stimulated echo diffusion preparation at 5 different diffusion times (70, 130, 190, 250, and 330 ms), at 4 different b‐values (0, 200, 400, 600, and 800 s/mm2) and 6 directions (orthogonal x, y, and z and diagonal xy, xz, and yz) and processed to obtain standard diffusion indices (mean diffusivity [MD] and fractional anisotropy [FA]) at each diffusion time.ResultsTime‐dependent diffusion was seen in muscle in healthy adult volunteers, boys with DMD, and age‐matched controls. Boys with DMD showed reduced MD and increased FA values in comparison to age matched controls across a range of diffusion times. A diffusion time of Δ = 190 ms had the largest effect size.ConclusionsThese results could be used to optimize diffusion imaging in this disease further and imply that these diffusion indices may become an important biomarker in monitoring progression in DMD in the future.
Combined replenishment and warehousing with contract commitments and flexibilities
Authors: Fan Jie , Ou Jinwen , Wang Guoqing 
Published: August 2021

AbstractThis paper studies a combined replenishment and warehouse size planning problem. A firm (3PW user) decides the replenishment quantities over a finite planning horizon to satisfy the time‐varying demands of a product. The firm has no warehouse and contracts with a third‐party warehousing (3PW) provider for storage space over the planning horizon. In the warehousing contract, the planning horizon is partitioned into a number of sessions, and each session also consists of multiple periods. The firm decides a stationary base storage size (BSS) of each session and has an opportunity to adjust the BSS at the beginning of each session. The firm also has the option to rent additional storage size beyond the BSS by paying higher rental cost in each individual period. We explore structural properties and develop a strongly polynomial‐time algorithm by applying geometric techniques to solve the firm's replenishment and warehouse sizing problem. We also conduct numerical experiments and provide important insights into the 3PW user's decisions and the 3PW contract design.
Evaluation of nutrition status of very preterm infants in neonatal intensive care units using different growth indicators
Authors: Wang Na , Zhang Jia , Yu Zhangbin , Tang Bin , Zhang Lin , Yin Yujie , Wang Zengqin , Li Shuangshuang , Jiang Shanyu , Hou Weiwei , Gao Yan , Wang Huaiyan , Chen Xiaoqing , Deng Xiaoyi , Lu Yi , Zhu Lingling , Bo Lin , Han Shuping 
Published: August 2021

AbstractBackground Nutrition status of very preterm infants in the neonatal intensive care unit (NICU) is strongly associated with postnatal growth. This study aimed to develop indicators of nutrition status using growth data of very preterm infants during hospitalization.MethodsThe data of 596 newborns from eight NICUs were retrospectively analyzed. Inclusion criteria were birth at <32 weeks’ gestation, NICU admission ≤24 h after delivery, and length of hospital stay ≥28 days. Three indicators were evaluated: (indicator I) prevalence of extrauterine growth restriction (EUGR); (indicator II) z‐score for change in weight from birth to discharge, adjusted for birth weight z‐score and gestational age; and (indicator III) change in weight z‐score from birth to discharge, adjusted for birth weight z‐score, gestational age, and time to regain birth weight. Using data from NICU 1 as the reference for the latter two indicators, we established linear regression models of the adjusted change in weight z‐score from birth to discharge. The difference between the observed value and the baseline value (calculated by the two models) served as the nutrition indices.ResultsThe prevalence of EUGR differed significantly between the eight NICUs (P = .009). Statistically significant differences were found between the mean indices calculated by the other two models (all P < .05).ConclusionsIndicator III, change in weight z‐score from birth to discharge (adjusted for birth weight z‐score, gestational age, and time to regain birth weight), appears to be the most accurate for evaluating the quality of nutrition in the NICU.
From clinical guidelines to practice: The nutrition elements for enhancing recovery after colorectal surgery
Authors: Hasil Leslee , Fenton Tanis R. , Ljungqvist Olle , Gillis Chelsia 
Published: August 2021

AbstractThe Enhanced Recovery After Surgery (ERAS) Care System improves patient outcomes. The ERAS Protocol describes multimodal, evidence‐based processes that are bundled into >20 care elements, and the ERAS Implementation Program provides strategies to guide the successful adoption of the care elements. Although formal training is essential to implement ERAS correctly, with this article we aim to bridge the gap between the nutritionally relevant care elements of the protocol and their implementation for colorectal surgery. This article also describes how dietitians can support optimal patient outcomes by playing an active role in implementing, monitoring, and evaluating ERAS practices.
Success and failures of telehealth during COVID‐19 should inform digital applications to combat obesity
Authors: Vasselli Joseph R. , Juray Susan , Trasino Steven E. 
Published: August 2021

AbstractBackgroundIn response to the COVID‐19 pandemic, telehealth digital applications (apps) permitted the delivery of health care to millions of individuals, including those with poor access to health services.AimTo review a body of evidence demonstrating that telehealth and mobile health (mHealth) apps can promote clinically meaningful weight loss, and thus hold potential to increase access to treatment and weight loss care for individuals suffering from obesity.ResultsData from COVID‐19 pandemic revealed that access to telehealth and mHealth remains a challenge for underserved communities that are disproportionately affected by obesity.ConclusionsThe development of telehealth and mHealth for obesity treatment must be informed by the success and failures of telehealth during the COVID‐19 pandemic. Failure to do so, risks alienating the very populations that stand most to benefit from telehealth and mHealth apps for obesity treatment.
FOXL2 in adult‐type granulosa cell tumour of the ovary: oncogene or tumour suppressor gene?
Authors: Pilsworth Jessica A , Todeschini Anne‐Laure , Neilson Samantha J , Cochrane Dawn R , Lai Daniel , Anttonen Mikko , Heikinheimo Markku , Huntsman David G , Veitia Reiner A 
Published: August 2021

AbstractA recurrent mutation in FOXL2 (c.402C>G; p.C134W) is present in over 95% of adult‐type granulosa cell tumours (AGCTs). In contrast, various loss‐of‐function mutations in FOXL2 lead to the development of blepharophimosis, ptosis, and epicanthus inversus syndrome (BPES). BPES is characterised by an eyelid malformation often accompanied with primary ovarian insufficiency. Two recent studies suggest that FOXL2 C402G is a gain‐ or change‐of‐function mutation with altered DNA‐binding specificity. Another study proposes that FOXL2 C402G is selectively targeted for degradation, inducing somatic haploinsufficiency, suggesting its role as a tumour suppressor. The latter study relies on data indicative of an FOXL2 allelic imbalance in AGCTs. Here we present RNA‐seq data as genetic evidence that no real allelic imbalance is observed at the transcriptomic level in AGCTs. Additionally, there is no loss of protein expression in tumours harbouring the mutated allele. These data and other features of this mutation compared to other oncogenes and tumour suppressor genes argue strongly against FOXL2 being a tumour suppressor in this context. Given the likelihood that FOXL2 C402G is oncogenic, targeting the variant protein or its downstream consequences is the most viable path forward to identifying an effective treatment for this cancer. © 2021 The Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
Experimental study on the effect of graphene nanoplatelets on the low‐velocity impact response of prestressed filament wound basalt‐based composite pressure vessels
Authors: Sepetcioglu Harun 
Published: August 2021

AbstractThe purpose of this study is to investigate the impact behavior of composite pressure vessel (CPV) in‐service case. Additionally, graphene nanoplatelets (GnPs) were introduced to epoxy resin. [±55°]4 basalt/epoxy specimens were manufactured using the filament‐winding method, and the low‐velocity impact (LVI) response was investigated. The LVI tests of CPVs were performed at energy levels of 2.5, 5, 7.5, 10, 15, 20, and 25 J under 50 bar internal pressure. The prestress value considering the internal pressure used under service conditions was taken as 1:5 of the burst pressure of the basalt/epoxy CPVs. After the LVI tests, the contact force–time and force–displacement curves were acquired. Also, absorbed energy values by CPVs were calculated over the obtained curves. The effects of GnPs on damage formations on basalt/epoxy CPVs under LVI loads were evaluated based on microscopic analysis. According to evaluations, damage formations such as matrix cracks on outer and inner surfaces of CPV, transverse cracks, and delamination were detected. Test liquid was detected on the impact surface at 25 J LVI test. The leakage observed due to the 25 J impact energy proves that damages can result in a leakage path. Consequently, the areas of damage formed in the cross sections perpendicular to the axis of basalt/epoxy CPVs decrease with the addition of GnPs, and the CPVs are more resistant to LVI effects.
Barrier Lypunov functions‐based nonsingular fixed‐time switching control for strict‐feedback nonlinear dynamics with full state constraints
Authors: Zhang Wenqian , Dong Wenhan , Lv Maolong , Liu Zongcheng , Zhou Yang , Feng Haoming 
Published: August 2021

AbstractThis work proposes a nonsingular adaptive fixed‐time switching control method for a class of strict‐feedback nonlinear dynamics subject to full state constraints. The peculiarity of this design lies in overcoming the singularity issue that typically appears in the existing backstepping‐based fixed‐time control methods caused by the iterative differentiation of fractional power terms as tracking errors approach to zero, while guaranteeing the nonviolation of full state constraints. Crucial in solving such singularity issue is to skillfully introduce a smooth switching between fractional power and integer power terms, which guarantees that fractional power term is confined within a positive interval all the time. An asymmetric time‐varying barrier Lyapunov function is delicately incorporated into control design, rendering state variables to be within prescribed time‐varying bounds. Besides, radial basis function neural network is employed to handle system unknown nonlinearities. It is rigorously proved that all the closed‐loop signals eventually converge to small regions around origin within fixed‐time. Comparative simulation results are finally given to validate the effectiveness and superiority of the proposed control strategy.
Further analysis for consensus of hybrid multiagent systems: A unified framework
Authors: Zhao Qi , Zheng Yuanshi , Liu Jian , Liu Bo 
Published: August 2021

AbstractHybrid multiagent systems exist widely in real world and have been applied in many engineering fields. In this article, we consider the consensus problem for the hybrid multiagent system consisting of continuous‐time and discrete‐time dynamic agents. Different from the previous works, in this article, the interactions between different agents no longer only occur at the sampling time, but continuous‐time dynamic agents can interact with their continuous‐time dynamic neighbors in real time. By using graph theory and differential mean value theorem of matrix function, a consensus criterion is obtained for the hybrid multiagent system. A unified framework is also established for the consensus of continuous‐time and discrete‐time multiagent systems. Finally, a simulation example is given to illustrate the validity of our protocol.
What a week! A moderated‐mediation crossover model for daily boundary violations at home and partner evening affect
Authors: Grotto Angela R. , Lyness Karen S. 
Published: August 2021

AbstractIncreasingly blurred boundaries allow work to breach home borders, disrupting personal tasks and goals which feel like violations to employees and thereby may trigger affective strain responses. Yet, the potential adverse effects of boundary violations at home on partner affective strain remains unexplored. Based on affective events and crossover theories, we considered the occurrence of violations at home as work‐related stressors originating at home and thereafter evoking emotional strain in partners through employees' own affective strain response. Based on the differential reactivity model, we expected employee affective strain responses to boundary violations at home and subsequent emotional transmission to partners would be exacerbated during a period (i.e., one week) of high emotional strain when employees and partners are hyper‐responsive to their home environments. Event data were collected for seven days from 69 employees and partners for 483 data points. Since the occurrence of homebound violations and associated effects on employees and partners likely fluctuates daily, a multilevel two‐stage moderated‐mediation model was tested. Results showed indirect effects of violations on partner affective strain through employee affective strain, with a backdrop of high emotional strain for the week moderating the affective event and crossover processes. Implications for scholars and organizations are discussed.
Scaffold 3D‐Printed from Metallic Nanoparticles‐Containing Ink Simultaneously Eradicates Tumor and Repairs Tumor‐Associated Bone Defects
Authors: Lin Huimin , Shi Shanwei , Lan Xinyue , Quan Xiaolong , Xu Qinqin , Yao Guangyu , Liu Jia , Shuai Xintao , Wang Chong , Li Xiang , Yu Meng 
Published: August 2021

AbstractBone metastasis occurs in about 70% of breast cancer patients. The surgical resection of metastatic tumors often leads to bone erosion and destruction, which greatly hinders the treatment and prognosis of breast cancer patients with bone metastasis. Herein, a bifunctional scaffold 3D‐printed from nanoink is fabricated to simultaneously eliminate the tumor cells and repair the tumor‐associated bone defects. The metallic polydopamine (PDA) nanoparticles (FeMg‐NPs) may effectively load and sustainably release the metal ions Fe3+ and Mg2+ in situ. Fe3+ exerts a chemodynamic therapy to synergize with the photothermal therapy induced by PDA with effective photothermal conversion under NIR laser, which efficiently eliminates the bone‐metastatic tumor. Meanwhile, the sustained release of osteoinductive Mg2+ from the bony porous 3D scaffold enhances the new bone formation in the bone defects. Taken together, the implantation of scaffold (FeMg‐SC) 3D‐printed from the FeMg‐NPs‐containing nanoink provides a novel strategy to simultaneously eradicate bone‐metastatic tumor and repair the tumor‐associated bone defects.