bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ecossistemas de conhecimento sobre Indústria 4.0 no Brasil: uma análise bibliométrica
Authors: Nascimento Mateus Rebouças 
Published: September 2021

Introdução: A produção de conhecimento na ciência se concretiza na interação colaborativa entre pesquisadores que investigam temáticas em comum, formando ecossistemas de conhecimento por meio de suas produções, neste sentido, o artigo objetiva mapear os principais atores (pesquisadores, universidades e agências de fomento) que constituem o ecossistema e os conhecimentos que o permeiam, em especial os centrados na indústria 4.0 em âmbito brasileiro. Método: Constitui uma pesquisa quantitativa, de cunho descritivo, utilizando técnicas bibliométricas mediante a uma análise dos trabalhos publicados sobre Indústria 4.0 na base de dados Web of Science nos últimos cinco anos, refinando a busca por país e selecionando o Brasil. Ao todo, 369 documentos produzidos no país foram analisados por meio do software métrico VOSviewer para construir redes de colaboração. Resultados: Destacam-se os autores Eduardo de Freitas Rocha Loures e Fernando Deschamps como principais produtores de conhecimento no ecossistema, bem como a CAPES e o CNPQ como atores norteadores no financiamento de pesquisas sobre a Indústria 4.0, as quais foram desenvolvidas no espaço da Universidade de São Paulo e Universidade Federal de Santa Catarina. Conclusão: Os ecossistemas de conhecimento na Indústria 4.0 são formados por universidades e agências de fomento públicas, que utilizam recursos para desenvolver no país tecnologias de inteligência artificial, internet das coisas, sistemas ciberfísicos, dentre outros conhecimentos norteadores.
Pengaruh Long Hot Water Treatment terhadap Perkecambahan dan Produksi Benih Tebu Bagal Mata 1 dan 2
Authors: Jati Wiwit Wicaksono , Kristini Ari , Putra Lilik Koesmihartono 
Published: September 2021

Salah satu penyakit penting terbawa benih adalah penyakit pembuluh yang disebabkan bakteri Leifsonia xyli sub sp xyli. Perlakuan LHWT dapat mengendalikan penyakit tersebut tetapi menyebabkan penurunan perkecambahan. Tujuan penelitian untuk mengetahui pengaruh LHWT terhadap perkecambahan beberapa varietas tebu bina dan produksi benih tebu varieta bina. Penelitian dilakukan pada tahun 2015, di P3GI Pasuruan Jawa Timur. Bahan yang digunakan yaitu benih tebu 5 varietas, fungisida benomil 0,6 gram/liter, urea 3,6 gram/liter. Peralatan yang digunakan yaitu water tank, termometer, waring, drum atau ember besar. Penelitian ini menggunakan rancangan petak terbagi. Petak utama terdiri dari 5 varietas yaitu PSDK 923, Bululawang, VMC 76-16, PSJK 922, PS 862. Anak petak terdiri dari 6 perlakuan yaitu kontrol benih bagal mata 1 dan mata 2, LHWT dengan perendaman larutan fungisida dan urea pada bagal mata 1, LHWT dengan perendaman larutan fungisida dan urea pada bagal mata 2, perawatan air panas suhu 50 0C 10 menit diikuti LHWT dan perendaman pada larutan fungisida dan urea pada bagal mata 1, dan perawatan air panas suhu 500C 10 menit diikuti LHWT dan perendaman pada larutan fungisida dan urea pada bagal mata 2. Hasil penelitian menunjukkan bahwa perlakuan pre treatment pada suhu 50 0C 10 menit yang diikuti LHWT dengan perendaman dalam larutan fungisida dan urea 20 menit pada benih tebu bagal mata 1 dan 2 dapat mengurangi penurunan perkecambahan dan pertumbuhan tebu lebih baik dibandingkan dengan post treatment tunggal. LHWT yang diikuti pre treatmen dapat meningkatkan produktivitas benih tebu dibandingkan LHWT tanpa pre treatmen.
Een gelijk speelveld voor EU-ondernemingen?
Authors: Dekker C.T. 
Published: September 2021

Een gelijk speelveld voor EU-ondernemingen? De staatssteunregeling in de handels- en samenwerkingsovereenkomst tussen de EU en het VK
In de Handels- en Samenwerkingsovereenkomst tussen de EU en het VK beoogt de EU met afspraken over subsidiecontrole de vervalsing van concurrentie door subsidies aan Britse ondernemingen tegen te gaan. In deze bijdrage wordt nagegaan in hoeverre de afspraken tussen de EU en het VK inderdaad voorzien in een regime in het VK dat op het gebied van – in EU-termen – staatssteun een gelijk speelveld waarborgt en wat kan worden ondernomen tegen steunverlening die in strijd met de gemaakte afspraken verstrekt wordt. Daarbij zal ook de ‘Subsidy Control Bill’ – het op 30 juni 2021 bij het ‘House of Commons’ ingediende wetsvoorstel voor een ‘Subsidy Control Act’ – in de beschouwing worden meegenomen.Handels- en Samenwerkingsovereenkomst tussen de Europese Unie en de Europese Gemeenschap voor Atoomenergie, enerzijds, en het Verenigd Koninkrijk van Groot-Brittannië en Noord-Ierland, anderzijds, ondertekend op 24 december 2020 (PbEU 2021, L 149/10).
A Study on the Effect of Integrated Ozone and UVC-LED Approaches on the Reduction of Salmonella typhimurium Bacteria in Droplets
Authors: Lee Jee-Hyun , Dinh Trieu-Vuong , Song Chang-Seon , Hong Kee-Jong , Kim Jo-Chun 
Published: September 2021

Abstract
In the wake of the SARS-CoV-2 pandemic, inactivating bioaerosols became a pivotal issue which helps to prevent the transmittance of SARS-CoV-2. Thus, the current study was conducted to investigate a potential inactivating method using both ozone (O3) and ultraviolet C (UVC). Individual and integrated effects of O3 and UVC were compared. A solution containing approximately 4~7.3×106 CFU/mL of Salmonella typhimurium bacteria was used to produce bacteria droplets. These droplets were exposed to O3 and UVC to determine the reduction rate of bacteria. The exposure times were set as 1 and 30 minutes. Ozone concentrations were 100 and 200 ppmv. UVC-LEDs were used as a UVC source. Peak wavelength of the UVC-LED was 275 nm and the irradiation dose was 0.77 mW/cm2. In terms of O3 and UVC-LED interaction, 194 ppmv styrene was used as a target compound to be removed. Considering the O3 and UVC-LED interaction, the presence of O3 could reduce the performance of the UVC-LED, and UVC-LED could also reduce significant amount of O3. The sequence of O3 and UVC-LED treatment was as follows: O3 was exposed at first, then UVC-LED, and this order showed the best reduction ratio (>99.9%). Therefore, if O3 and UVC-LED is used to disinfect Salmonella typhimurium bacteria contained in droplets, bacteria should be separately exposed to O3 and UVC-LED in order to improve the inactivation efficiency.
Fibrinogen to Albumin Ratio Predicts Burden of Coronary Artery Disease in Patients with NSTEMI
Authors: DEMİR Muhammed , ÖZBEK Mehmet , AKTAN Adem , ERTAŞ Faruk 
Published: September 2021

Objective: Fibrinogen plasma level rises in the event of inflammatory cases. It is known that there is a powerful intercourse between fibrinogen level and plasma viscosity. Albumin plasma level dropes during the inflammatory cases. The aim of this work determine significance of fibrinogen albumin ratio (FAR) as a indicator emphases the burden of atherosclerosis.
Method: The study included 83 patients diagnosed with non-ST-segment elevation myocardial infarction (NSTEMI) between January and September 2015. The definition of NSTEMI was made according to “Definition of Third Universal Myocardial Infarction” guidelines published on 2013 by European Society of Cardiology. Burden of atherosclerosis was evaluated by Syntax score (SS) and Gensini Score. Patients were seperated two groups as medium-high SS (n=23) and low SS (n=60). FAR levels were compared.
Results: FAR was 80.71 ± 30.3 in low SS group and 120 ± 49.72 in the mid-high SS group respectively (p
Samlede anmeldelser
Authors: Det Danske Sprog- og Litteraturselskab Redaktionen 
Published: September 2021

Anmeldelser af:
Ole Togeby: Mie Fem. Nielsen og Svend Skriver (red.): Metodekogebogen – 130 analysemetoder fra humaniora og samfundsvidenskab
Simon Skovgaard Boeck: Bodil Ejrnæs: Gammeldansk Bibel. Studier i en dansk bibeloversættelse fra middelalderen
Kjeld Kristensen: Georg Stubkjær Adamsen m.fl. (red.): Dialekter i rigt mål
Anna Sandberg: Stephan Michael Schröder: Literatur als Bellographie. Der Krieg von 1864 in der dänischen Literatur
Jens Kramshøj Flinker: Torsten Bøgh Thomsen: Skyggepunkter. Menneske, natur og materialitet i H.C. Andersens forfatterskab
Karin Sanders: Johnny Kondrup: Bjergtaget. Illusion og forf.relse fra Søren Kierkegaard til Karen Blixen
Kristian Himmelstrup: Henrik Yde: NEXØ - Martin Andersen Nexøs liv og værk
Erik Skyum-Nielsen: Jan Inge Sørbø: Nynorsk litteraturhistorie
Negara dan Permasalahan State Building di Abad XXI
Authors: B.H.S. Alessandro , Noviyanti Nona Siska 
Published: September 2021

In this book, Francis Fukuyama delivers his arguments concering the issue about the lack of "organizational tradition" in several "failed" or "weak" states, which in turns becomes the greatest threat to the contemporary world order. Fukuyama argues that the United States, and the West in general, after rightly intervening in such states either militarily or economically (most often through institutions like IMF or World Bank), have failed to transfer institutional and public- and private- sector capability to them. Although their objective is to "create self-sustaining state institutions that can survive the withdrawal of outside intervention," the developed world has met its failure, setting people of the developing countries up for "large disappointments." For much of the last half-century, the trend has been to weaken the state. Now, the evidence suggests that a new approach is required, one that goes beyond simply shrinking or enlarging the state, and begins to deal with enabling the state to be more effective based on local conditions. Fukuyama suggests that the answer lies in providing states with internal organizational structure and, above all, a culture that enables strong leaders and government institutions to enforce capitalist and free-market values. While some basic outcomes are to be expected, the way each nation gets there will be different.
Integrative analysis of miRNA–mRNA network in idiopathic membranous nephropathy by bioinformatics analysis
Authors: He Wenfang , Zhang Jinshi , Yuan Shizhu , Liang Mingzhu , Chen Weidong , Jin Juan 
Published: September 2021

Background
Currently, several specific antigens, M-type receptor for secretory phospholipase A2(PLA2R1), thrombospondin type-1 domain-containing 7A(THSD7A), and neural epidermal growth factor-like 1 protein (NELL-1), are discovered associated with the onset of idiopathic membranous nephropathy (IMN). But the pathomechanisms of IMN still need to be further claried. Understanding the mechanisms of IMN is required to improve its diagnosis and treatment.

Methods
In this study, we constructed miRNA regulatory networks to investigate IMN development. Moreover, miRNAs and mRNAs that were differentially expressed between Idiopathic Membranous Nephropathy (IMN) patients and normal controls were examined using the GSE115857 dataset and our previous sequence study. DE miRNA target genes were determined based on the FUNRICH software, starBase, miRDB, and miRWalk, and an miRNA-mRNA network was designed using DE-mRNAs that were negatively correlated with DE-miRNAs. The miRNA-mRNA network contained 228 miRNA-mRNA pairs. Thereafter, we conducted KEGG pathway, GO functional annotation, immune-related gene screening, protein interaction networks, and potential hub gene analyses. Furthermore, 10 miRNAs and 10 genes were determined and preliminarily validated using the validation dataset from GEO. Finally, we identified which pair may offer more accurate diagnosis and therapeutic targets for IMN.

Results
Two miRNA-mRNA pairs, miR-155-5p-FOS and miR-146a-5p-BTG2, were differentially expressed in IMN, indicating that these genes may affect IMN through immune processes. These findings may offer more accurate diagnoses and therapeutic targets for IMN.
Diferentes critérios de definição da periodontite em puérperas jovens e sua associação com o baixo peso ao nascer.
Authors: Sacramento dos Santos Mércia , Sá Lopes Laíra , Gomes-Filho Isaac , Passos-Soares Johelle , Teixeira Cangussu Maria Cristina , Pereira Vianna Maria Isabel 
Published: September 2021

Objetivo: comparar três critérios de definição da periodontite na associação da doença periodontal com o baixo peso ao nascer (BPN) em uma população de puérperas jovens de Salvador, BA. Metodologia: aplicaram-se três diferentes critérios de definição da periodontite a uma amostra de 202 mães de bebês com peso ≥ 2.500g (controles) e de 97 mães de bebês com BPN (casos) pertencentes a uma base de dados de um estudo caso-controle prévio. Para a análise da associação entre periodontite e BPN, construíram-se modelos para os três critérios. A regressão logística não-condicional foi realizada para estimar a Odds Ratio (OR) baseada em Intervalos de Confiança a 95%. Resultados: a idade média das mães foi de 26,29 anos. A maioria declarou-se negra/parda (92.64%), não fumante (94,65%) e possuir renda de até um salário-mínimo (61,20%). A ocorrência da periodontite variou de 22,41% a 94,31%, segundo o critério usado. Estimando-se a OR ajustada, a periodontite definida pelo critério 1 [ORajust. = 0,94, IC (95%)= 0,56–1,56], critério 2 [ORajust=1,18, IC(95%)= 0,65-2,13] e critério 3 [ORajust= 0,87, IC(95%)=0,37-3,22] não esteve associada com o BPN. Conclusão: flexibilizar o critério de definição interferiu na magnitude das medidas de ocorrência, mas não influenciou a análise de associação entre a periodontite e o BPN.
Efeito modulador do Previcox® sobre a ação carcinogênica da doxorrubicina por meio do teste de tumores epiteliais (ETT) em Drosophila melanogaster
Authors: Bontempo Nayara Júnia , Capelari Orsolin Priscila 
Published: September 2021

Introdução: a superexpressão da COX-2 relaciona-se com o aumento da produção de fatores de crescimento vascular e como consequência, com o desenvolvimento tumoral. O Firocoxib é um anti-inflamatório não esteroidal utilizado para inflamação associada à osteoartrite em cães. É o inibidor mais seletivo da COX-2, reduzindo eficientemente a ação desta enzima. Estudos indicam os benefícios do Firocoxib na terapia antineoplásica. Objetivo: este trabalho objetivou avaliar o efeito modulador do Firocoxib sobre a ação da doxorrubicina (DXR) por meio do teste de tumores epiteliais (ETT) em Drosophila melanogaster. Metodologia: foram preparadas três concentrações de Firocoxib: 2,5; 5 e 10 mg/mL, utilizadas isoladamente e em associação à doxorrubicina. O tratamento ocorreu com larvas de D. melanogaster descendentes do cruzamento de fêmeas wts/TM3 com machos mwh/mwh. Resultados: os resultados sugerem que o Firocoxib possui atividade moduladora sobre a ação carcinogênica da DXR, pois houve redução significativa nas frequências tumorais dos indivíduos tratados com diferentes concentrações de Firocoxib em cotratamento com a doxorrubicina quando comparadas à frequência tumoral do controle positivo. Conclusão: conclui-se que, nas presentes condições experimentais, o Firocoxib reduziu a frequência de tumores induzidos pela doxorrubicina em D. melanogaster.
Autoficção - Interstícios Libertários da Dramaturgia
Authors: Sperber Suzi Frankl , Jacopini Juliano Ricci 
Published: September 2021

Trataremos da autoficção na composição de dramaturgias contemporâneas como algo inerente à liberdade criadora, apostando no relato sobre si como espécie de caminho para a compreensão de si e ação no mundo, o qual depende de níveis de ficcionalização para gerar acordos que construam uma nova realidade. É disso que precisamos sempre: um mergulho – se possível abissal – em nossa realidade para reinventá-la como ato ético via expressividades singulares, que estão no bojo de nosso território estético. Estabeleceremos um diálogo entre a perspectiva de teatro horizontal (JACOPINI, 2018), a teoria da pulsão de ficção (SPERBER, 2009) e postulados sobre dramaturgia em campo expandido (SÁNCHEZ, 2010 e QUILICI, 2014), enxergando a expansão do campo como uma possibilidade de trabalho sobre si mesmo nas criações contemporâneas, numa tentativa de reconexão com o mundo, numa espécie de expurgo da realidade exterior, no empenho de reconstruí-la.What do you want to do ?New mailCopy What do you want to do ?New mailCopy What do you want to do ?New mailCopy
Beckett e Oida: o desamparo como dissolvência do real
Authors: Pocidônio Rodrigo , Bonfitto Matteo 
Published: September 2021

Esse artigo, escrito no fluxo de um jogo, adota como metodologia a ‘Prática como Pesquisa’, olhar que pode ser visto como sendo de matriz fenomenológica e que faz das experiências psicofísicas ignições concretas de elaborações e invenções. O objetivo aqui é perceber o processo criativo do espetáculo Fim de Partida - a partir do olhar de dois atores que o vivenciaram - como sendo gerador de campos dramatúrgicos, que envolvem nesse caso, além da fricção entre o texto de Samuel Beckett e a encenação de Yoshi Oida, também o escancaramento de múltiplos jogos de representação. À guisa de conclusão abrimos a questão de que talvez tais jogos, uma vez expostos, permitam a percepção da noção de ‘desamparo’ visto enquanto abertura perceptiva e criem espaço para a emergência de dissolvências no âmbito do assim chamado real.
Computational investigation of metal organic frameworks as potential drug carriers for antihypertensive amlodipine
Authors: Liu Jiaqi , Yang Zhen , Che Yuanyuan , Zhang Yaojie , Zhang Zhihao , Zhao Chun‐Xia 
Published: September 2021

AbstractMetal organic frameworks (MOFs) have been recognized as promising materials for biomedical applications such as drug storage and drug delivery. In this study, grand canonical Monte Carlo simulations were carried out to investigate the adsorption of an antihypertensive drug amlodipine in 28 different MOFs. Among them, 19 MOFs, which were identified to outperform those traditional materials, were screened to perform molecular dynamic (MD) simulations in order to select promising candidates for drug carriers of amlodipine, and then five representative MOFs were explored further to elucidate the mechanism of amlodipine adsorption. This is the first study to investigate the correlations between self‐diffusion coefficients of drug molecule and its adsorption heat, pore volumes, and largest cavity diameters of MOF‐74 series. This work provides valuable insights in drug adsorption and diffusion mechanisms in MOFs at the molecular level enabling us to speed up the MD screening of suitable drug carriers prior to experiments.
KI‐Methoden zur Integration tragwerksplanerischen Wissens in frühe Phasen des Gebäudeentwurfsprozesses
Authors: Schnellenbach‐Held Martina , Steiner Daniel 
Published: September 2021

AbstractEine frühe Integration der tragwerksplanerischen Expertise in den Prozess des Gebäudeentwurfs ermöglicht eine effiziente Unterstützung der hochkomplexen Planungsentscheidungen. Zur Bereitstellung und Verwendung des dafür geeigneten Erfahrungswissens des Ingenieurwesens wurde ein wissensbasiertes System (WBS) entwickelt. Dieses kann durch den Einsatz von entwicklungsstufenbezogenen unscharfen Wissensbanken sowie zugehöriger Inferenzsysteme eine Beurteilung von Tragstrukturen und Vorschläge von Entwurfsoptionen leisten. Das Entwicklungsstufensystem enthält eine Bewertung von Tragsystemen basierend auf der Possibilitätstheorie und umfasst Konzepte der adaptiven Entwicklungsstufen. Durch den Einsatz der leicht verständlichen Formulierung von Regeln im Modus Ponens und von Inferenzmechanismen der Fuzzy Logic wird dabei die Nachahmung des menschlichen Entscheidungsverhaltens ermöglicht. Zur Akquise des Wissens werden Parameterstudien mit der Berechnung und Bemessung von Tragelementen des Stahlbetonbaus durchgeführt. Praxiserfahrungen bestimmen die für die im üblichen Hochbau zu erwartenden Strukturen zu berücksichtigenden Wertebereiche. Mechanismen zur Berücksichtigung einer möglichen Ungewissheit von Entwurfsgrößen werden bereitgestellt. Das resultierende WBS ermöglicht schließlich eine Steigerung der Effizienz des Planungsprozesses bereits in frühen Planungsphasen.
Does it matter when I quit? Could I just cut down some? Links between trimester‐specific smoking amount, preterm birth, and low birth weight
Authors: Osborne Jahla B. , Bailey Beth A. 
Published: September 2021

AbstractBackgroundSubstantial evidence demonstrates the harms of pregnancy smoking. Due to the need for very large data sets, less data exist to inform decisions about when quitting should occur, or whether a certain amount of reduction is beneficial.ObjectivesOur goal was to examine the effect of timing and amount of pregnancy smoking on low birth weight (LBW) and preterm birth (PTB).MethodsData for 3 years of registered births in Tennessee were available and included standard birth certificate information.ResultsOf 241,616 women, 15.7% smoked at conception, and those who quit as early as the first trimester had significantly increased adjusted odds of LBW (27%) and PTB (14%) compared to nonsmokers, with this effect largely driven by smoking 10+ cigarettes per day. Smoking into the second trimester but quitting prior to the third also predicted increases in LBW and PTB compared to both not smoking at all and smoking only in the first trimester. Smoking to delivery predicted a 2.8‐fold increased likelihood of LBW, and a 2.1‐fold increased rate of PTB. Any level of smoking after the first trimester substantially increased the odds of poor outcomes compared to both nonsmoking and smoking only in the first trimester.ConclusionsFindings suggest that to avoid LBW or PTB, pregnant smokers should be advised that quitting completely by the end of the first trimester is important, and that continuing to smoke even <5 cigarettes per day after that point substantially increases the potential for of adverse outcomes.
Faculty views of CBE, self‐efficacy, and institutional support: An exploratory study
Authors: Prokes Christopher , Lowenthal Patrick R. , Snelson Chareen , Rice Kerry 
Published: September 2021

AbstractCompetency‐based education (CBE) is essentially an approach to teaching and learning featuring flexible pacing, robust competencies, and an emphasis on student completion. CBE differs from traditional education that focuses instead more on seat time and credit hours. Though CBE has existed on college campuses in many forms, faculty are often inexperienced in teaching CBE. Facing growing demands for CBE, institutions must find ways to prepare faculty to take part in CBE. This mixed methods study explored faculty views of CBE, their self‐efficacy, and beliefs about support mechanisms needed for those teaching and delivering CBE. Findings suggest faculty have mixed though balanced views of CBE, generally high self‐efficacy due to the importance of mastery experiences, and believe in the importance of specific learning opportunities in an environment built on collaboration to ensure CBE faculty are supported and can thrive. Findings can help institutions with CBE or those considering it to support faculty and ensure they are trained in teaching courses in this modality.
New‐onset vitiligo following mRNA‐1273 (Moderna) COVID‐19 vaccination
Authors: Kaminetsky Joshua , Rudikoff Donald 
Published: September 2021

AbstractThe COVID‐19 mRNA vaccines not only provide remarkable protection but also have been characterized by an overall safe and well‐tolerated side effect profile. Herein, we discuss a rare but manageable cutaneous reaction to COVID vaccination in order to further characterize dermatologic reactions and stress the continued vaccination of eligible patients.