bluuebunny/crossref_metadata_2025_split huggingface dataset:
Realidad Aumentada en Educación Primaria: Revisión sistemática
Authors: Rodríguez Caldera Beatriz 
Published: October 2021

La Realidad Aumentada es una tecnología versátil y funcional que permite enriquecer nuestro entorno añadiendo información virtual a la realidad, posibilitando la creación de nuevos espacios formativos más motivadores e interactivos para los alumnos. Esta tecnología puede integrarse en las diferentes etapas formativas, pero su aplicación en Educación Primaria podría traer beneficios por las posibilidades que ofrece.
En esta investigación se realiza un análisis sistemático de documentación científica, que permite identificar los principales usos y aplicaciones de la Realidad Aumentada en Educación Primaria en los últimos 5 años en España.
A través de este trabajo se confirma que la introducción de la RA en la práctica docente trae consigo beneficios como el aumento de la motivación e interés en los alumnos o la mejora de los procesos de enseñanza y aprendizaje. Además se identifican los principales usos de esta tecnología en esta etapa, destacando que permite enriquecer la realidad y los materiales educativos y promover actividades de enseñanza y aprendizaje donde los estudiantes crean y comparten sus propios proyectos aumentados.
Revisión bibliográfica y análisis sobre b-learning y la socialización del alumnado en educación primaria
Authors: Román Sánchez Francisco Esteban , Marín Suelves Diana , Peirats Chacón José 
Published: October 2021

al sistema educativo hace algunos años y se ha implantado con fuerza, sobre todo a nivel universitario. El objetivo del estudio es analizar las investigaciones publicadas sobre b-learning en la etapa de Educación Primaria a través de una revisión bibliográfica centrada en los últimos 5 años. Aunque el estudio confirma que la tendencia no ha cambiado y el modelo sigue teniendo más presencia en niveles superiores, poco a poco, se van viendo estudios sobre b-learning en Educación Primaria. En su mayoría, son estudios enfocados a la eficacia en cuanto al rendimiento académico, pero podemos encontrar investigaciones donde el foco de estudio secentra en otras aportaciones del modelo. Dentro de la modalidad mixta, el modelo más utilizado y popularizado es el aula invertida, modelo que asume principios pedagógicos tales como el aprendizaje activo, significativo, social, cooperativo… En estos tiempos de pandemia, donde se necesita la distancia social, el reto al que se enfrenta este modelo supone suplir debidamente los beneficios que conlleva la interacción social con propuestas innovadoras e interesantes para el proceso de enseñanza y aprendizaje.
Producción de recursos auditivos en la enseñanza a estudiantes con discapacidad visual
Authors: Araque Rangel Adriana Carolina 
Published: October 2021

Buscando apoyar el potencial formativo de los estudiantes con discapacidad visual se proponen lineamientos dirigidos a la creación de medios auditivos por docentes, ejecutando una investigación de tipo descriptivo documental, considerando las leyes y normas que rigen los procesos de inclusión y de formación en personas con discapacidad visual. Se contó con la participación de seis profesores y un estudiante, a quienes se les aplicó un cuestionario estructurado y una entrevista, encontrando que ningún profesor hace uso de algún recurso o material didactico dirigido a personas con esta discapacidad, concluyendo que es necesario incorporar el uso de la tiflotecnología dentro del aula haciendo que el estudiante se sienta más motivado a aprender, facilitando la comprensión de los contenidos. Además, el docente debe brindar a los estudiantes con discapacidad visual un sustento en la formación educativa llevando un seguimiento en las actividades planteadas, así como identificar los problemas que se presenten en el proceso de enseñanza y saber elegir los recursos apropiados para beneficiar su proceso de formación.
Educar desde casa en tiempos de pandemia. Un reto tecnológico para el Equipo de Atención Educativa Hospitalaria y Domiciliaria de la Región de Murcia
Authors: Gómez García Lucía 
Published: October 2021

La forma de entender la educación a raíz de la emergencia sanitaria producida por la COVID-19 ha cambiado. El sistema educativo se ha enfrentado a un nuevo reto de adaptación y transformación de nuestra realidad educativa. El objetivo de este artículo es presentar las estrategias que el Servicio de Atención Educativa Domiciliaria (SAED) ha ofrecido. Para ello, se ha desarrollado una metodología vanguardista que se concreta en una plataforma donde se ha recreado un entorno amigable para el alumno y unos recursos que ofrecen un andamiaje básico para la actividad docente. Se seleccionaron una serie de plataformas online con las que un equipo de profesionales optimizó el proceso de enseñanza-aprendizaje telemático. Esta investigación subraya la atención recibida por el alumnado con necesidades educativas especiales. Los resultados reflexionan sobre esta revisión de la educación en un contexto excepcional en la que el material educativo e interactivo ha servido para estimular diferentes tipos de alumnado en una situación excepcional.
Diclofenac degradation based on shape-controlled cuprous oxide nanoparticles prepared by using ionic liquid
Authors: Huang Jialei , Luo Yan 
Published: October 2021

Abstract
Persulfate oxidation technology is widely used in wastewater treatment, but there are still many disadvantages, such as high energy consumption, side reaction and narrow pH applicability. Copper oxides can activate persulfate steadily with higher efficiency. In this paper, a novel preparation method of shape-controlled cuprous oxide (Cu2O) nanoparticles featured with high catalytic performance was explored. It was found that adding ionic liquid 1-butyl-3-methylimidazolium bromide ([BMIM]Br) during preparation of Cu2O can improve the degradation rate of diclofenac (DCF). Cu2O nanoparticles possess good stability in consecutive cycling tests, which was confirmed by X-ray photoelectron spectroscopy. The possible mechanism of Cu2O activating persulfate at different initial pH conditions was discussed based on electron paramagnetic resonance spin-trapping experiment. It was found that DCF was efficiently degraded in the Cu2O/peroxydisulfate (PDS) system within a broad pH range from 5 to 11. It proved via a quenching experiment that the activation process of PDS mainly occurs on the surface layer of Cu2O nanoparticles. As a result, shape-controlled Cu2O nanoparticles prepared by ionic liquid are expected to be used for in situ chemical oxidation, which is an effective oxidation processes to degrade DCF remaining in surface water and ground water.
Education, APOE ε4, and Cognition in Individuals with Subjective Cognitive Decline with Worry in the SILCODE Study
Authors: Chen Guanqun , Lin Li , Yang Kun , Han Ying 
Published: October 2021

Background:
Education could offer a protective effect on cognition in individuals with
Subjective Cognitive Decline (SCD), which is considered to be the early stage of Alzheimer’s Disease
(AD). However, the effect of education on cognition in SCD individuals with SCD-plus features
is not clear.

Objective:
The aim of the study was to explore the effect of education on cognition in SCD individ-
uals with SCD-plus features.

Methods:
A total of 234 individuals with SCD were included from the Sino Longitudinal Study on
Cognitive Decline (SILCODE). Cognition was assessed across 4 domains (memory, executive, language,
and general cognitive functions). Multiple linear regression models were constructed to examine
the effect of education on cognitive scores in individuals without worry (n=91) and with worry
(n=143). Furthermore, we assessed differences in effects between APOE ε4 noncarriers and
APOE ε4 carriers in both groups.

Results :
Multiple linear regression analysis showed a positive effect of education on memory, executive,
and language cognition in individuals without worry and all cognitive domains in individuals
with worry. Furthermore, we found a positive effect of education on executive cognition in
APOE ε4 noncarriers without worry and language and general cognition in APOE ε4 carriers without
worry. Meanwhile, education had a positive effect on all cognitive domains in APOE ε4 noncarriers
with worry and executive, language, and general cognition in APOE ε4 carriers with worry.

Conclusion:
This study indicates that education has the potential to delay or reduce cognitive dec-
line in SCD individuals with SCD-plus features.
Facile Synthesis of Vicinal Halohydrins Via Organocatalytic Halogen
Nucleophile-Induced Regioselective Opening of Epoxides
Authors: Sinha Niharika , Singhal Anchal , Sharma Deeksha , Chauhan Shiv Murat Singh 
Published: October 2021

Background:
The calix[4]pyrrole is reported as a novel organocatalyst for regioselective
ring-opening of epoxides under mild reaction conditions.

Methods:
The reaction involves elemental halogen as a nucleophile to afford vicinal halohydrins
in good to excellent yield (75-95%).

Results:
The reactivity of the halide ion in the reaction is governed by different factors, including
solvent polarity, temperature and non-covalent interactions of the functional group present on
calix[4]pyrrole moiety with halide ions.

Conclusion:
An efficient methodology has been developed for the regioselective synthesis of halohydrins
in good to excellent yields.
Nio Nanoparticles: A Highly Efficient Catalyst for the One-Pot Three-
Component Synthesis of Pyrano [2, 3-D] Pyrimidine Derivatives in Green
Reaction Media
Authors: Sabbaghnasab Ellahe , Sheikhhosseini Enayatollah 
Published: October 2021

Abstract:
NiO nanoparticles are utilized to effectively strengthen annulated pyrano [2,3-d]
pyrimidine synthesis through primary Knoevenagel, following Micheal and ultimate heterocyclization
reactions of aldehyde, malononitrile, and barbituric acid. The characteristics of NiO
nanoparticles are identified using advanced techniques, such as IR, UV, EDX, XRD, SEM, and
TEM. The nano-NiO particles are mostly below < 100 nm in size with uniform spherical shapes.
The adopted approach is advantages owing to its simple processing, relatively short reaction time,
often good to high average yields, convenient workability, and environmental friendliness.
Recent Advances in Organic Synthesis of 3-Amino- or 4-Aminocoumarins
Authors: Chen Zhiwei , Zeng Piaopiao , Zhang Shuo , Sun Jie 
Published: October 2021

:
Coumarin is a privileged scaffold that contains the unique 2H-chromen-2-one motif, and its
derivatives are widely distributed in nature, especially in plants. In recent years, due to their diverse
pharmacological activities and remarkable photochemical properties, they have attracted significant
attention from scientists, which has also prompted the research on the synthesis approaches and the
availability of substrates for these compounds. This article is a brief description of the methods for the
synthesis of various coumarin derivatives via two- or multi-component reactions involving 3-amino
or 4-aminocoumarin reported during 2015-2021. This review may help expand the development of
various analogues with coumarin as the basic unit.
Chemistry of 2-(Piperazin-1-yl) Quinoline-3-Carbaldehydes
Authors: Salem Mohammed A. , Gouda Moustafa A. , El-Bana Ghada G. 
Published: October 2021

Abstract:
This review described the preparation of 2- chloroquinoline-3-carbaldehyde derivatives 18
through Vilsmeier-Haack formylation of N-arylacetamides and the use of them as a key intermediate
for the preparation of 2-(piperazin-1-yl) quinoline-3-carbaldehydes. The synthesis of the 2-
(piperazin-1-yl) quinolines derivatives was explained through the following chemical reactions:
acylation, sulfonylation, Claisen-Schmidt condensation, 1, 3-dipolar cycloaddition, one-pot
multicomponent reactions (MCRs), reductive amination, Grignard reaction and Kabachnik-Field’s
reaction.
Nanoparticle Production of Zingiber officinale Roscoe Rhizome Extracts
by ESS (Expansion of Supercritical Solution)
Authors: Raofie Farhad , Rezvanjoo Zahra 
Published: October 2021

Aims:
To propose a modified RESS method of herbal pharmaceutical extracts nanoparticle
production.

Background:
A vast number of methods have been applied to water-insoluble pharmaceuticals to improve their solubility. Nanoparticle production of pharmaceuticals is considered as one of the high-speed
ways to improve solubility.

Objective:
Supercritical CO2 was applied to extract Zingiber officinale Roscoe rhizome pharmaceutical.
Then, a modified RESS (Rapid Expansion of Supercritical Solution) method, called ESS (Expansion of
Supercritical Solution), was exerted to obtain NPs (nanoparticles) of the extracted pharmaceuticals.

Methods:
Initially, applying high pressure in supercritical CO2 contributed to the extract dissolution such
that supercritical CO2 was saturated with the sample. Then, by decreasing the pressure, an expansion occurred in the saturated medium. This expansion reduced the power of supercritical CO2 solvent and induced the sample nanoparticle nucleation in the needle valve.

Results:
LC-MS (Liquid Chromatography-Mass Spectrometry) and EDX (energy dispersive X-ray spectroscopy) result provided solid evidence for the presence of anti-cancer pharmaceutical, [6]-Gingerol, in
the extract. The medium size of the nanoparticles in FESEM (Field Emission Scanning Electron Microscopy) analysis was 36 nm. The most satisfactory parameters for a 2 mg mL-1 feeding solution were the
initial pressure of 350 atm, secondary pressure of 160 atm, equilibrating time of 10 min, precipitating
time of 20 min, and temperature of 48 °C.

Conclusion:
Unlike rapid expansion of supercritical solution methodology, in this technique, the initial
and secondary pressures were permanently above the critical pressure to provide a gentle expansion,
which contributes to the production of uniform and small particles. The obtained uniform NPs had a narrow size distribution. Consequently, ESS technique can be considered as an efficient technique for improving the solubility of hydrophobic pharmaceuticals, such as [6]-gingerol.
Bibliometric Analysis of the Research on Photo-electrocatalysis and Its
Possible Application to Wastewater Treatment
Authors: Palmas Simonetta , Vacca Annalisa , Mascia Michele , Mais Laura 
Published: October 2021

Background:
Possible applications of photoelectrocatalysis in the field of environmentally
sustainable processes have inspired an exponentially increasing number of papers in the last decades.
Less frequently, bibliometric analyses are presented, which are especially useful when a considerable
amount of data is involved: metadata can be viewed from micro to macro perspective and may suggest
ideas for future research.

Objective:
The objective of this study is to derive information on the research trends and to individuate
possible gaps in specific topics, as well information on the authors and their related countries and
institutes, and to quantify possible cooperation patterns between them.

Methods:
In addition to the classic data analyses immediately available on the database, such as the
trend of the number of publications per year and the list of the most active authors or countries, the
bibliometric analysis has been carried out using the VOSviewer software. Co-authorship and cocitation
analyses have been performed, as well as co-occurrence of the keywords explicitly indicated
by the authors.

Conclusion:
Based on the publications in the SCOPUS database, the present work analysed the
metadata relating to scientific articles published in the last two decades, dedicated to the research on
photo-electrocatalytic processes and their possible application on wastewater treatment. Based on the
list of the references present in the examined papers, the co-authorship analysis and the co-citation
analysis also allowed the identification of the authors and the publications which have been most influential
on the research on the examined topics. Indication has been obtained on the trend of the main
topics investigated in time, as well as the current gaps in terms of content-wise and geographic cooperation.
Comparison Between Male and Female Survivors of Sexual Abuse and Assault in Relation to Age at Admission to Therapy, Age of Onset, and Age at Last Sexual Assault: Retrospective Observational Study
Authors: AL-Asadi Ali M 
Published: October 2021

Background
Sexual abuse and sexual assault are complex phenomena that involve many factors (or correlates) and have many health and financial implications for individuals, families, and society. Every correlate needs to be studied in detail, individually and in relation to other correlates. Only with a thorough understanding of these correlates can more efficient and targeted prevention and intervention programs be designed.

Objective
The purpose of this study was to examine the differences between male and female survivors of sexual abuse and sexual assault regarding the correlates of the survivors’ age of onset of assault, age at the last assault, and age at which they entered therapy.

Methods
Therapists at eight sexual assault centers in the province of Alberta, Canada, completed a questionnaire on each of their clients over a period of 7 years. A total of 3302 participants, of whom 2901 (87.86%) were female and 401 (12.1%) were male survivors of sexual abuse and assault, were included in this study. Mostly descriptive analyses were carried out on the 4 variables of concern in this study.

Results
Regarding the number of survivors who sought therapy, female survivors outnumbered male survivors by a ratio of 7:1, with different ratios for different age groups. As children age, their risk of being sexually assaulted for the first time decreases. Male children are more likely to be sexually abused at a younger age, whereas female children are more vulnerable to being assaulted at all ages, particularly in adolescence. The mean age of onset of sexual abuse was found to be 6.71 (SD 2.86) years, and the odds of experiencing the first sexual assault during childhood, as opposed to adolescence, were 4:1 for females and 9:1 for males. Male survivors were two times more likely than female survivors to experience their first sexual assault in childhood. The vast majority of survivors sought help many years after being sexually assaulted, and male survivors waited an average of 3 years longer from the last sexual assault before seeking therapy.

Conclusions
The majority of survivors of sexual abuse and sexual assault live with the consequences for many years before they seek help, and a large proportion of male survivors are not likely to seek help.
Supporting Management of Noncommunicable Diseases With Mobile Health (mHealth) Apps: Experimental Study
Authors: Kela Neta , Eytam Eleanor , Katz Adi 
Published: October 2021

Background
Noncommunicable diseases (NCDs) are the leading global health problem in this century and are the principal causes of death and health care spending worldwide. Mobile health (mHealth) apps can help manage and prevent NCDs if people are willing to use them as supportive tools. Still, many people are reluctant to adopt these technologies. Implementing new apps could result in earlier intervention for many health conditions, preventing more serious complications.

Objective
This research project aimed to test the factors that facilitate the adoption of mHealth apps by users with NCDs. We focused on determining, first, what user interface (UI) qualities and complexity levels appeal to users in evaluating mHealth apps. We also wanted to determine whether people prefer that the data collected by an mHealth app be analyzed using a physician or an artificial intelligence (AI) algorithm. The contribution of this work is both theoretical and practical. We examined users’ considerations when adopting mHealth apps that promote healthy lifestyles and helped them manage their NCDs. Our results can also help direct mHealth app UI designers to focus on the most appealing aspects of our findings.

Methods
A total of 347 respondents volunteered to rate 3 models of mHealth apps based on 16 items that measured instrumentality, aesthetics, and symbolism. Respondents rated each model after reading 1 of 2 different scenarios. In one scenario, a physician analyzed the data, whereas, in the other, the data were analyzed by an AI algorithm. These scenarios tested the degree of trust people placed in AI algorithms versus the “human touch” of a human physician regarding analyzing data collected by an mHealth app.

Results
As shown by the responses, the involvement of a human physician in the application had a significant effect (P<.001) on the perceived instrumentality of the simple model. The complex model with more controls was rated significantly more aesthetic when associated with a physician performing data analysis rather than an AI algorithm (P=.03).

Conclusions
Generally, when participants found a human touch in the mHealth app (connection to a human physician who they assumed would analyze their data), they judged the app more favorably. Simple models were evaluated more positively than complex ones, and aesthetics and symbolism were salient predictors of preference. These trends suggest that designers and developers of mHealth apps should keep the designs simple and pay special attention to aesthetics and symbolic value.