bluuebunny/crossref_metadata_2025_split huggingface dataset:
Manejo de desechos infecciosos en el hospital Marco Vinicio Iza de la ciudad de Nueva Loja durante el periodo octubre-diciembre del 2011
Authors: Lima Pozo Miriam Nataly , Romo Torres Alicia Daniela 
Published: October 2021

En el hospital "Marco Vinicio Iza" de la ciudad de Nueva Loja, se ha evidenciado un inadecuado manejo de recolección, transporte y almacenamiento de desechos infecciosos, por parte del personal de salud, limpieza y administrativos; por to tanto hemos vista la necesidad de realizar el trabajo de investigación en esta institución, en donde se logró obtener resultados a través de diferentes técnicas como son la observación y la aplicación de encuestas a los que laboran en esta casa de salud.
Los resultados obtenidos indican que existe un inadecuado manejo de los desechos aproximadamente en un 70%, ante esta problemática, se establece un plan de intervención que está encaminado a realizar un protocolo de manejo de desechos infecciosos para este hospital y proponer un circulo de mejoramiento continuo con objetivo de mejorar el conocimiento del reglamento para el manejo adecuado de desechos infecciosos generados en las instituciones de salud en el Ecuador y por ende tener un correcto manejo de los desechos, reduciendo así el riesgos de transmisión de enfermedades.
Conocimientos, prácticas y actitudes de los adolescentes del segundo año de bachillerato del Instituto Tecnológico Superior "Vicente Fierro" en el año lectivo 2011-2012 sobre el uso de métodos anticonceptivos.
Authors: Narvaez Figueroa Betty Alexandra , Rivadeneira Vela Ertha Johaiva 
Published: October 2021

La adolescencia es una fase de desarrollo de todo ser humano, donde se presentan diferentes cambios físicos y psicológicos, lo cual conlleva una nueva etapa de formación de la persona, así como la manifestación de diferentes necesidades como la sexualidad. Es por esto que el objetivo de esta investigación fue determinar el conocimiento, la actitud y la práctica de los adolescentes del segundo aña de bachillerato del Instituto Tecnológico Superior "Vicente Fierro" sección Diurna, sabré el uso métodos anticonceptivos, se aplica coma técnica la encuesta, y el cuestionario como instrumento de investigación, lo que proporciono coma resultado que si existe el conocimiento en un 87%, y la práctica sexual activa llega a un 67%, pero con una actitud de no siempre utilizar en forma correcta los métodos anticonceptivos, puesto que no utilizan un método anticonceptivo habitual, donde el más utilizado es el preservativo con un 67%, y se encuentra que el 19% de ellos al momento de mantener relaciones sexuales no utilizan ningún método anticonceptivo. Esto incentive) a la socialización con los estudiantes sobre los métodos anticonceptivos, para mejorar la calidad de conocimientos que poseen y así tengan una mayor seguridad al momento de la práctica sexual.
La hipótesis se logró comprobar, ya que el conocimiento, práctica y actitud, influyen en el uso de los diferentes métodos anticonceptivos. Esta fue una investigación de tipo descriptiva, transversal y de acción, puesto que se elabor6 en un tiempo determinado.
CURRENT STATE OF THE LAW ON CRIMINAL LIABILITY FOR VIOLATION OF THE PROCEDURE OF ENTRY INTO THE TEMPORARILY OCCUPIED TERRITORY OF UKRAINE AND EXIT
Authors: Деркач В. Г. 
Published: October 2021

The article examines the current state of the law on criminal liability for violation of the procedure for entering and leaving the temporarily occupied territory of Ukraine, as a result of which Art. 332-1 of the Criminal Code of Ukraine to decriminalize at least because the regime of the temporarily occupied territories is temporary, and the temporary articles of the criminal law to the world have not yet been known. The Constitution of Ukraine in Art. 17 declared that the protection of the sovereignty and territorial integrity of Ukraine, ensuring its economic and information security are the most important functions of the state, the business of the entire Ukrainian people. The defense of Ukraine, protection of its sovereignty, territorial integrity and inviolability are entrusted to the Armed Forces of Ukraine. Ensuring state security and protection of the state border of Ukraine are entrusted to the relevant military formations and law enforcement agencies of the state, the organization and procedure of which are determined by law. In late 2013 - early 2014, the Russian Federation, taking advantage of the problems in our army to perform such functions, launched an open armed aggression, which, in addition to killing tens of thousands of Ukrainians, led to the illegal annexation of Crimea and occupation of Donetsk and Luhansk regions. In fact, the state border with the Russian Federation in eastern Ukraine has become a line of demarcation between the territory controlled by the state of Ukraine and the temporarily occupied territory of Ukraine. The Ukrainian Parliament reacted to this acute problem in a rather predictable way - on April 15, 2014, the Law of Ukraine № 1207-VII “On Ensuring the Rights and Freedoms of Citizens and the Legal Regime in the Temporarily Occupied Territory of Ukraine” was adopted. 332-1 "Violation of the procedure for entering and leaving the temporarily occupied territory of Ukraine." Such a decision of the Verkhovna Rada of Ukraine provoked both sharp discussions in the science of criminal law and problems in the application of this norm in practice. Thus, during the period under study from 2014 to February 2021, we registered 212 cases of violation of the procedure for entering and leaving the temporarily occupied territory of Ukraine. However, according to the State Judicial Administration of Ukraine, the courts of Ukraine have handed down 30 court convictions for violating the procedure for entering and leaving the temporarily occupied territory of Ukraine. Of these, 7 were handed down in 2015, 21 in 2016, and one sentence each in 2017 and 2019.
DIRECTIONS FOR IMPROVING THE LEGAL AND ORGANIZATIONAL FRAMEWORK FOR THE USE OF ADMINISTRATIVE AND LEGAL COERCION BY THE POLICE
Authors: Калашнік В. П. 
Published: October 2021

The article, based on the analysis of scientific views of scientists and current legislation, substantiates the importance and necessity of scientific research on improving the mechanism of administrative and legal coercion in the work of the National Police of Ukraine. Various scientific positions concerning the development of organizational and legal bases for improving administrative coercion in the police are analyzed. It is concluded that today, both in science and at the official state level, there is no single, systematic, well-oriented view that would reveal ways to improve the legal and organizational framework for the use of administrative and legal coercion by the police. In most cases, this issue is revealed in the context of the development of a specific component of the National Police of Ukraine, which ignores key, individual signs of administrative coercion, which really need to be reworked and rethought in accordance with the current vector of law enforcement. The directions of improvement of legal and organizational bases of application of administrative-legal coercion by the National police of Ukraine are formulated, namely: a) it is necessary to fix definition of concept of administrative coercion in the current Law of Ukraine "About national police" from 02.07.2015 № 580-VIII that to understand its essence more deeply, but also to orient more precisely legal and normative-legal regulation of the last; b) the list and interpretation of the forms of administrative and legal coercion, as well as all the methods provided by these forms and the subjects of their implementation should be clearly outlined; c) requires the gradual implementation of the institution of "presumption of justice of the police", which is to expand the guarantees of policing in the context of the use of coercive measures; strengthening legal liability for non-compliance with the requirements of police officers; improving the regulations of procedures for the implementation of coercive measures of influence; d) it is necessary to strengthen the study and use of foreign experience of administrative coercion in the police of foreign countries through the systematic involvement of representatives of the National Police of Ukraine in various seminars, conferences and other information cooperation, and to ensure the organization of such events in Ukraine to involve law enforcement authorities of foreign countries.
The Impact of Cultural and Translational Studies on Modern Comparative Literature Studies
Authors: Mehrpouyan Azadeh , Zakeri Elahesadat 
Published: October 2021

Modern comparative literature with globalization phenomenon extends linguistic and political boundaries, even for conserving and revitalizing languages particularly minor languages with cultural and ethnic exchanges. Such this emergence of comparative literature might return from contemporary translational and cultural studies as crucial and effective factors in the study of comparative literature. The role, relationship, and impact of translation and cultural studies on modern comparative literature are explored via a descriptive analysis. Translational and cultural studies in current comparative literature studies facilitate the relevant studies and they play a supplementary role for literary study. This study confirms a significant relationship exists among contemporary translational, cultural, and literary works intangibly and inevitably that helps to study comparative literary works. The findings report cultural and translational studies can be fruity informing literary studies, new writing styles besides intercultural conversation; nevertheless, scholars of comparative literature have argued that their discipline has been significantly subsumed and substituted by translation studies. The results indicate contemporary translation and cultural studies have paved the way for comparative literature researchers to achieve cultural knowledge and to strengthen the culture with developing national literature.
Translating The Disaster of Mourice Blanchot Between Ann Smock and Azzedine Chentouf
Authors: Laachiri Soufiane 
Published: October 2021

The present article attempts to present a succinct and circumspect comparison between two different translations for Mourice Blanchot’s book « L’écriture du désastre ».The first translation was performed by Ann Smock in 1995 and was from French into English, while the other translation was skillfully produced by Azzedine Chentouf from French into Arabic in 2018. The contrast in attitudes and translational fertilization has provided us with ample opportunities to study, reflect on, and rethink the nexus of Blanchot’s philosophy from different linguistic perspectives. However, in our attempt to formulate our judgments on the English and Arabic versions of the book, we can judge by an escapable logic and with analytical evidence that the English translation entitled « The writing of the disaster » has intensified the hold of a literal translation that makes the chances of being close to the original meaning of the source text depressingly small. Chentouf’s translation, on the other hand, remains profoundly meaningful; it is capable of going down into the marrow of Blanchot’s thought to assert understanding of his intellectual complexities. In brief, despite the triviality of the advanced examples, we are certain that Azzedine Chentouf, through his Arabic translation, knows the hard philosophical portrait of Mourice Blanchot in its inclusiveness. Therefore, it is no surprise that every choice he makes in this translation explains his tremendous efforts as a philosopher first before being ranked as a translator.
Peran Beban Kerja dalam Memoderasi Pengaruh Religiositas Terhadap Keterikatan Kerja
Authors: Ali Nur 
Published: October 2021

Berdasarkan teori Job Demand-Resources (JD-R), penelitian ini menguji pengaruh antara religiositas terhadap keterikatan kerja dan peran moderasi beban kerja pada pengaruh religiositas terhadap keterikatan kerja. Hasil survei terhadap 64 karyawan di PT Telekomunikasi Indonesia, Tbk Kandatel Jombang mengungkapkan bahwa religiositas berpengaruh positif terhadap keterikatan kerja. Temuan penelitian juga menggambarkan pentingnya membedakan antara tuntutan tantangan dan rintangan dalam konteks stres kerja di mana beban kerja mempengaruhi manfaat religiositas terhadap keterikatan kerja. Studi ini menyoroti penerapan teori JD-R dan memperluas kerangka teoritis dengan memeriksa hubungan antara religiositas dan keterikatan kerja. Penelitian ini berkontribusi pada literatur keterikatan kerja dengan memperkenalkan religiositas sebagai sumber daya pribadi yang meningkatkan keterikatan kerja dan meningkatkan kesejahteraan.
Effect of Novel Polymer-Free Nitrogen-Doped Titanium Dioxide Film–Coated Coronary Stent Loaded With Mycophenolic Acid
Authors: Shim Jae Won , Kim Sung Soo , Kim Hyun Kuk , Bae In Ho , Park Dae Sung , Park Jun-Kyu , Kim Jae Un , Kim Han Byul , Lee Min Young , Kim Joong Sun , Kim Jung Ha , Koo Bon-Sang , Jeong Kang-Jin , Kim Sun-Uk , Kim Min Chul , Sim Doo Sun , Hong Young Joon , Ahn Youngkeun , Lim Kyung Seob , Jeong Myung Ho 
Published: October 2021

Background: Titanium is commonly used in blood-exposed medical devices because it has superior blood compatibility. Mycophenolic acid inhibits the proliferation of vascular smooth muscle cells. This study examined the effect of a non-polymer TiO2 thin film–coated stent with mycophenolic acid in a porcine coronary overstretch restenosis model.Methods: Thirty coronary arteries in 15 pigs were randomized into three groups in which the coronary arteries were treated with a TiO2 film–coated stent with mycophenolic acid (NTM, n = 10), everolimus-eluting stent with biodegradable polymer (EES, n = 10), or TiO2 film–coated stent (NT, n = 10). A histopathologic analysis was performed 28 days after the stenting.Results: There were no significant intergroup differences in injury score, internal elastic lamina area, or inflammation score. Percent area stenosis was significantly smaller in the NTM and EES groups than in the NT group (36.1 ± 13.63% vs. 31.6 ± 7.74% vs. 45.5 ± 18.96%, respectively, p = 0.0003). Fibrin score was greater in the EES group than in the NTM and NT groups [2.0 (range, 2.0–2.0) vs. 1.0 (range, 1.0–1.75) vs. 1.0 (range, 1.0–1.0), respectively, p &lt; 0.0001]. The in-stent occlusion rate measured by micro-computed tomography demonstrated similar percent area stenosis rates on histology analysis (36.1 ± 15.10% in NTM vs. 31.6 ± 8.89% in EES vs. 45.5 ± 17.26% in NT, p &lt; 0.05).Conclusion: The NTM more effectively reduced neointima proliferation than the NT. Moreover, the inhibitory effect of NTM on smooth muscle cell proliferation was not inferior to that of the polymer-based EES with lower fibrin deposition in this porcine coronary restenosis model.
Chromium-Salophen as a Soluble or Silica-Supported Co-Catalyst for the Fixation of CO2 Onto Styrene Oxide at Low Temperatures
Authors: Balas Matthieu , K/Bidi Ludivine , Launay Franck , Villanneau Richard 
Published: October 2021

Addition of a soluble or a supported CrIII-salophen complex as a co-catalyst greatly enhances the catalytic activity of Bu4NBr for the formation of styrene carbonate from styrene epoxide and CO2. Their combination with a very low co-catalyst:Bu4NBr:styrene oxide molar ratio = 1:2:112 (corresponding to 0.9 mol% of CrIII co-catalyst) led to an almost complete conversion of styrene oxide after 7 h at 80°C under an initial pressure of CO2 of 11 bar and to a selectivity in styrene carbonate of 100%. The covalent heterogenization of the complex was achieved through the formation of an amide bond with a functionalized {NH2}-SBA-15 silica support. In both conditions, the use of these CrIII catalysts allowed excellent conversion of styrene already at 50°C (69 and 47% after 24 h, respectively, in homogeneous and heterogeneous conditions). Comparison with our previous work using other metal cations from the transition metals particularly highlights the preponderant effect of the nature of the metal cation as a co-catalyst in this reaction, that may be linked to its calculated binding energy to the epoxides. Both co-catalysts were successfully reused four times without any appreciable loss of performance.
Cost-Effectiveness Evaluation of Add-on Empagliflozin in Patients With Heart Failure and a Reduced Ejection Fraction From the Healthcare System's Perspective in the Asia-Pacific Region
Authors: Liao Chia-Te , Yang Chun-Ting , Kuo Fang-Hsiu , Lee Mei-Chuan , Chang Wei-Ting , Tang Hsin-Ju , Hua Yi-Ming , Chang Hung-Yu , Chen Zhih-Cherng , Strong Carol , Ou Huang-Tz , Toh Han Siong 
Published: October 2021

Background:EMPEROR-Reduced trial provides promising evidence on the efficacy of empagliflozin adding to the standard treatment in patients with heart failure and reduced ejection fraction (HFrEF). This study aimed to investigate the cost-effectiveness of add-on empagliflozin vs. standard therapy alone in HFrEF from the perspective of the Asia-Pacific healthcare systems.Methods:A Markov model was constructed to simulate HFrEF patients and to project the lifetime direct medical costs and quality-adjusted life years (QALY) of both therapies. Transitional probabilities were derived from the EMPEROR-Reduced trial. Country-specific costs and utilities were extracted from published resources. Incremental cost-effectiveness ratio (ICER) against willingness to pay (WTP) threshold was used to examine the cost-effectiveness. A series of sensitivity analyses was performed to ensure the robustness of the results.Results:The ICERs of add-on empagliflozin vs. standard therapy alone in HFrEF were US$20,508, US$24,046, US$8,846, US$53,791, US$21,543, and US$20,982 per QALY gained in Taiwan, Japan, South Korea, Singapore, Thailand, and Australia, respectively. Across these countries, the probabilities of being cost-effective for using add-on empagliflozin under the WTP threshold of 3-times country-specific gross domestic product per capita were 93.7% in Taiwan, 95.6% in Japan, 96.3% in South Korea, 94.2% Singapore, 51.9% in Thailand, and 95.9% in Australia. The probabilities were reduced when shortening the time horizon, assuming the same cardiovascular mortality for both treatments, and setting lower WTP thresholds.Conclusion:Adding empagliflozin to HFrEF treatment is expected to be a cost-effective option among the Asia-Pacific countries. The cost-effectiveness is influenced by the WTP thresholds of different countries.
Pathogenesis of Enamel-Renal Syndrome Associated Gingival Fibromatosis: A Proteomic Approach
Authors: Simancas Escorcia Victor , Guillou Clément , Abbad Lilia , Derrien Louise , Rodrigues Rezende Costa Claudio , Cannaya Vidjea , Benassarou Mourad , Chatziantoniou Christos , Berdal Ariane , Acevedo Ana Carolina , Cases Olivier , Cosette Pascal , Kozyraki Renata 
Published: October 2021

The enamel renal syndrome (ERS) is a rare disorder featured by amelogenesis imperfecta, gingival fibromatosis and nephrocalcinosis. ERS is caused by bi-allelic mutations in the secretory pathway pseudokinase FAM20A. How mutations in FAM20A may modify the gingival connective tissue homeostasis and cause fibromatosis is currently unknown. We here analyzed conditioned media of gingival fibroblasts (GFs) obtained from four unrelated ERS patients carrying distinct mutations and control subjects. Secretomic analysis identified 109 dysregulated proteins whose abundance had increased (69 proteins) or decreased (40 proteins) at least 1.5-fold compared to control GFs. Proteins over-represented were mainly involved in extracellular matrix organization, collagen fibril assembly, and biomineralization whereas those under-represented were extracellular matrix-associated proteins. More specifically, transforming growth factor-beta 2, a member of the TGFβ family involved in both mineralization and fibrosis was strongly increased in samples from GFs of ERS patients and so were various known targets of the TGFβ signaling pathway including Collagens, Matrix metallopeptidase 2 and Fibronectin. For the over-expressed proteins quantitative RT-PCR analysis showed increased transcript levels, suggesting increased synthesis and this was further confirmed at the tissue level. Additional immunohistochemical and western blot analyses showed activation and nuclear localization of the classical TGFβ effector phospho-Smad3 in both ERS gingival tissue and ERS GFs. Exposure of the mutant cells to TGFB1 further upregulated the expression of TGFβ targets suggesting that this pathway could be a central player in the pathogenesis of the ERS gingival fibromatosis.In conclusion our data strongly suggest that TGFβ -induced modifications of the extracellular matrix contribute to the pathogenesis of ERS. To our knowledge this is the first proteomic-based analysis of FAM20A-associated modifications.
Non-Invasive Detection of Fetal Vascular Endothelial Function in Gestational Diabetes Mellitus
Authors: Chen Yunyu , Huang Danping , Liu Jinrong , Zeng Fangling , Tang Guoyi , Lei Wenjia , Wang Haiyu , Jiang Yanmin , Shentu Weihui , Wang Hongying 
Published: October 2021

ObjectivesEndothelial dysfunction in the fetuses of women with gestational diabetes mellitus (GDM) is associated with their subsequent cardiovascular events. Prenatal assessment of endothelial function in fetuses exposed to intrauterine hyperglycemic environment remains challenging. The aim of this study was to assess the fetal vascular endothelial function in GDM patients using color M-mode derived aortic propagation velocity (APV) and evaluate the correlation of APV with endothelial function biomarkers.MethodsThis observational cross-sectional study included 31 gestational diabetic mothers and 30 healthy pregnant mothers from August 2019 to January 2020. Clinical data were compared between the groups. Fetal APV was measured using color M-mode echocardiography at late gestation. Concentrations of endothelial biomarkers including von Willebrand Factor (vWF), vascular endothelial-cadherin and endothelin-1 in umbilical cord serum were assessed. Measurements between diabetic group and controls were compared.ResultsvWF was the only endothelial functional marker that differed between the two groups. Fetuses in the GDM group had significantly lower APV levels and higher vWF levels compared with the healthy controls (P &lt; 0.05). There was a moderate but significant correlation between APV and vWF (r =−0.58, P &lt; 0.001). There were no associations between APV and ventricular wall thickness or umbilical artery pulsatility index.ConclusionsColor M-mode propagation velocity of aorta is a non-invasive, practical method that correlates well with GDM and fetal endothelial function. This novel metric could contribute to recognizing early vascular functional alterations and hence represents a potential strategy for early risk factor surveillance and risk modification.