bluuebunny/crossref_metadata_2025_split huggingface dataset:
Spatiotemporal transcriptional dynamics of the cycling mouse oviduct
Authors: Roberson Elle C. , Battenhouse Anna M. , Garge Riddhiman K. , Tran Ngan Kim , Marcotte Edward M. , Wallingford John B. 
Published: January 2021

AbstractFemale fertility in mammals requires iterative remodeling of the entire adult female reproductive tract across the menstrual/estrous cycle. However, while transcriptome dynamics across the estrous cycle have been reported in human and bovine models, no global analysis of gene expression across the estrous cycle has yet been reported for the mouse. Here, we examined the cellular composition and global transcriptional dynamics of the mouse oviduct along the anteroposterior axis and across the estrous cycle. We observed robust patterns of differential gene expression along the anteroposterior axis, but we found surprisingly few changes in gene expression across the estrous cycle. Notable gene expression differences along the anteroposterior axis included a surprising enrichment for genes related to embryonic development, such as Hox and Wnt genes. The relatively stable transcriptional dynamics across the estrous cycle differ markedly from other mammals, leading us to speculate that this is an evolutionarily derived state that may reflect the extremely rapid five-day mouse estrous cycle. This dataset fills a critical gap by providing an important genomic resource for a highly tractable genetic model of mammalian female reproduction.
Risk management in the public sector: a structured literature review
Authors: Bracci Enrico , Tallaki Mouhcine , Gobbo Giorgia , Papi Luca 
Published: January 2021

PurposeRisk management (RM) is receiving increasing academic and practitioner attention in the public sector. Despite this, there is a lack of systematization of this body of knowledge. The purpose of this paper is to analyze the state of art by examining the knowledge gaps and defining the emerging themes of RM in the public sector to guide future research agendas.Design/methodology/approachThe authors conducted a structured literature review (SLR). They analyzed 63 papers, by using Scopus database, published from 1990 to 2018. All papers were categorized and analyzed according to 11 criteria defined by the literature.FindingsResults show that there is an increasing attention to RM with a need for more effort to consolidate research knowledge. Findings also established a lack of theorization, with a limited explanatory capacity of most studies. The paper defined four main areas for future developments to increase the body of knowledge. Namely, RM and managerial systems (i.e. MCSs and performance management), integrating RM systems and the building blocks of RM that the authors identify will also play a role in helping the authors to understand the diffusion of RM within public sector organizations.Originality/valueDespite the increasing attention to RM in the public sector, more research is required. Considering RM in public sector risks to be a “black box”, this paper revealed some new insights that could help to analyze better RM in the public sector, to open the black box and to avoid a symbolic use of the RM. In fact, integration with the managerial systems and the strengthening of the building block could help to exploit the potential of RM in the public sector.
Re-territorialising the policing of cybercrime in the post-COVID-19 era: towards a new vision of local democratic cyber policing
Authors: Horgan Shane , Collier Ben , Jones Richard , Shepherd Lynsay 
Published: January 2021

Purpose
The purpose of this study is to develop the theorisation of cybercrime in the context of the pandemic, and to sketch out a vision of how law enforcement might respond to a transformed landscape of online crime and offending.

Design/methodology/approach
This conceptual paper draws on empirical evidence from a range of sources (including official statistics) and the existing research literature, and revisits routine activities theory to illuminate the way that cybercrime patterns are being transformed by the pandemic.

Findings
The pandemic is reshaping the routine activities of societies en masse, leading to changes in the ecology of risk and opportunity for cybercrime. There is evidence of a large increase in the prevalence of cybercrime as a result, yet much of this has a paradoxically “local” character.

Practical implications
The authors identify specific practical implications for law enforcement, namely, that the role of local police in policing cybercrime should be re-envisioned, with a democratic, community-oriented approach at its heart.

Originality/value
The theoretical perspective outlined is a novel and critical development of a well-established framework, opening up new paths to the theorisation of cybercrime and cybercrime policing. The authors’ suggestions for practitioners have the potential for direct impact, both at the level of practice and in terms of broader imaginaries and organisation of police and policing.
A paradigm shift in financial landscape: encouraging collaboration and innovation among Indonesian FinTech lending players
Authors: Utami Ami Fitri , Ekaputra Irwan Adi 
Published: January 2021

PurposeThis paper aims to examine about the nature and strategy of current competitive dynamics by FinTech lending Indonesia players.Design/methodology/approachThis paper uses both primary and secondary data. Interviews of several executives of a FinTech lending firm are done to gain direct insight of how the firms strategize their business operation. On the other hand, secondary data from internet search (e.g., OJK’s Website, FinTech Lending firm’s websites) are used to grasp the overview of the industrial landscape.FindingsThe study confirms that differentiation, collaboration, compliance and strong internal resources (e.g. team and funding) are the most pivotal elements for FinTech lending success. The study also confirmed the FinTech lending industrial landscape as an emerging and fragmented industry.Research limitations/implicationsThis paper offers an original and detailed solution about how the FinTech lending company strategies may survive in a dynamic competition. The paper also shows the industrial analysis of the FinTech lending industry, which is rarely discussed in previous research. However, this study only focused on the lending sub-sector of FinTech, and the sample for primary data is highly limited (only three interviews).Practical implicationsThis paper proposes a strategy that can be conducted by FinTech lending companies to achieve their business goals, including business growth, profits and improve financial inclusion in Indonesia. This perspective can act as a means to create practical modus operandi for policymakers and practitioners, especially FinTech lending companies in Indonesia.Originality/valueThis paper offers an original and detailed solution about how the FinTech lending company strategies may survive in adynamic competition. This study also provides a theoretical framework for use in further empirical research into the process of resource mobilization from FinTech lending Indonesia companies.
A cross-national diagnosis of infodemics: comparing the topical and temporal features of misinformation around COVID-19 in China, India, the US, Germany and France
Authors: Zeng Jing , Chan Chung-hong 
Published: January 2021

PurposeThis study empirically investigates how the COVID-infodemic manifests differently in different languages and in different countries. This paper focuses on the topical and temporal features of misinformation related to COVID-19 in five countries.Design/methodology/approachCOVID-related misinformation was retrieved from 4,487 fact-checked articles. A novel approach to conducting cross-lingual topic extraction was applied. The rectr algorithm, empowered by aligned word-embedding, was utilised. To examine how the COVID-infodemic interplays with the pandemic, a time series analysis was used to construct and compare their temporal development.FindingsThe cross-lingual topic model findings reveal the topical characteristics of each country. On an aggregated level, health misinformation represents only a small portion of the COVID-infodemic. The time series results indicate that, for most countries, the infodemic curve fluctuates with the epidemic curve. In this study, this form of infodemic is referred to as “point-source infodemic”. The second type of infodemic is continuous infodemic, which is seen in India and the United States (US). In those two countries, the infodemic is predominantly caused by political misinformation; its temporal distribution appears to be largely unrelated to the epidemic development.Originality/valueDespite the growing attention given to misinformation research, existing scholarship is dominated by single-country or mono-lingual research. This study takes a cross-national and cross-lingual comparative approach to investigate the problem of online misinformation. This paper demonstrates how the technological barrier of cross-lingual topic analysis can be overcome with aligned word-embedding algorithms.Peer review:The peer review history for this article is available at: https://publons.com/publon/10.1108/OIR-09-2020-0417
Elevation and aspect determine the differences in soil properties and plant species diversity on Himalayan mountain summits
Authors: Hamid Maroof , Khuroo Anzar Ahmad , Malik Akhtar Hussain , Ahmad Rameez , Singh Chandra Prakash 
Published: January 2021

AbstractAlthough vegetation has been the focus of recent studies on mountain summits, little is known about smaller‐scale spatial patterns of soil physico‐chemical properties. Here, we report patterns and drivers of soil physico‐chemical properties and their role in shaping the plant diversity on mountain summits of the Himalaya. Using the globally standardized Multi‐Summit Approach, four summits along an elevation gradient from treeline to nival zone were selected in Kashmir Himalaya. Sampling of the summits was carried out to collect soil samples together with vegetation data and soil temperature. The results revealed that there is a significant effect of elevation and aspect on soil physico‐chemical properties and species richness on the summits. A significant correlation was observed between soil parameters and elevation, indicating that summits with distinct pool of species possess distinct soil properties. Moreover, soil temperature clearly determined the aspect‐wise distribution of soil parameters and species richness. The Canonical Correspondence Analysis revealed that elevation, soil temperature, pH, electrical conductivity and C:N ratio were more prominent in determining the plant diversity on summits. Our results demonstrate that mosaic of micro‐climatic conditions driven by elevation and aspect favor a suite of soil properties, which in turn determine the patterns of species diversity on the mountain summits. The present study, therefore, enhances understanding of the spatial patterns of variation in soil and plant diversity of mountain summits, which will help to monitor, model and predict how these ecologically unique ecosystems will respond to climate warming in the Himalaya, with implications for such environments elsewhere.
Putting the Australian Economy on the Scales
Authors: Leigh Andrew 
Published: January 2021

AbstractBased on the increasing size of the service sector, some believe that growth in advanced countries has come without much change in the physical weight of output. To investigate the question, I generate rough estimates of the physical weight of Australian output from 1831 to 2018, using data on the weight of traded goods. These ballpark estimates imply that the weight of annual output increased from around 50,000 tonnes to around 800 million tonnes. Over the long term, a 10 per cent increase in real GDP was associated with a 12 per cent increase in the physical weight of output.
What drives crisis readiness? An assessment of managers in the United States: The effects of market turbulence, perceived likelihood of a crisis, small‐ to medium‐sized enterprises and innovative capacity
Authors: Parnell John A. , Crandall William “Rick” 
Published: January 2021

AbstractWe investigate four contributors to crisis readiness: market turbulence, innovative capacity, perceived likelihood of a crisis (PLC) and firm size. Results from a PLS‐SEM assessment of 284 managers in the United States suggest that market turbulence is not only a precursor to crisis readiness but also affects PLC and innovative capacity in firms. We conclude that managers in SMEs were more likely to expect a crisis but less prepared to address one when it strikes.
Rule omission, rule migration and the limits of financial industry power
Authors: CHALMERS ADAM WILLIAM , MALIK TEHMINAH NAZ 
Published: January 2021

AbstractThis paper seeks to deepen our understanding of financial industry lobbying efforts that result in specific regulatory rules being dropped from the regulatory agenda, or what we call ‘rule omission’. Critically, existing research either ignores rule omission or characterizes it as the pinnacle of lobbying success. We argue that only in carefully mapping out industry preferences and tracking what happens to rules following their omission can we say something about the extent to which finance wins or loses in its effort to shape regulation. Our analysis is based on two in‐depth case studies from the European Union: (1) solvency rules in the Institutions for Occupational Retirement Provision Directive (IORPP II), where rule omission does reflect a strong case of industry influence; and (2) short selling rules in the Alternative Investment Fund Managers Directive (AIFMD), a case of rule omission resulting in more stringent rules over industry activities.
Do dual eligible beneficiaries experience better health care in special needs plans?
Authors: Haviland Amelia M. , Elliott Marc N. , Klein David J. , Orr Nate , Hambarsoomian Katrin , Zaslavsky Alan M. 
Published: January 2021

AbstractObjectiveDual Eligible Special Needs Plans (D‐SNPs) were intended to provide better care for beneficiaries eligible for both Medicare and Medicaid through better coordination of these two programs.Data Sources671 913 dual eligible (DE) respondents to the 2009‐2019 Medicare Consumer Assessment of Healthcare Providers and Systems (CAHPS) survey.Study DesignWe compared the 2015‐2019 experiences of DE beneficiaries in D‐SNPs relative to fee‐for‐service Medicare (FFS) and non‐SNP Medicare Advantage (MA) using propensity‐score weighted linear regression. Comparisons were made to 2009‐2014. 12 patient experience measures were considered.Data Collection MethodsAnnual mail survey with telephone follow‐up of non‐respondents.Principal FindingsMore than 65% of DE beneficiaries enrolled in FFS. Of 12 measures, D‐SNP performance was higher than non‐SNP MA on two (P < .05), lower than non‐SNP MA on two (P < .05), and higher than FFS on four (P < .01). DE beneficiaries did not report better coordination of care in D‐SNPs. D‐SNP performance was often worse than other coverage types in prior periods.ConclusionsRelative to FFS Medicare, DE beneficiaries report higher immunization rates in D‐SNPs, but slight or no better performance on other dimensions of patient experience. New requirements in 2021 may help D‐SNPs attain their goal of better care coordination.
Distinct roles of two RDL GABA receptors in fipronil action in the diamondback moth (Plutella xylostella)
Authors: Li Ben‐Jie , Wang Kun‐Kun , Chen Dong‐Ping , Yan Ying , Cai Xu‐Ling , Chen Hui‐Min , Dong Ke , Lin Fei , Xu Han‐Hong 
Published: January 2021

AbstractThe phenylpyrazole insecticide fipronil blocks resistance to dieldrin (RDL) γ‐aminobutyric acid (GABA) receptors in insects, thereby impairing inhibitory neurotransmission. Some insect species, such as the diamondback moth (Plutella xylostella), possess more than one Rdl gene. The involvement of multiple Rdls in fipronil toxicity and resistance remains largely unknown. In this study, we investigated the roles of two Rdl genes, PxRdl1 and PxRdl2, in P. xylostella fipronil action. In Xenopus oocytes, PxRDL2 receptors were 40 times less sensitive to fipronil than PxRDL1. PxRDL2 receptors were also less sensitive to GABA compared with PxRDL1. Knockout of the fipronil‐sensitive PxRdl1 reduced the fipronil potency 10‐fold, whereas knockout of the fipronil‐resistant PxRdl2 enhanced the fipronil potency 4.4‐fold. Furthermore, in two fipronil‐resistant diamondback moth field populations, PxRdl2 expression was elevated 3.7‐ and 4.1‐fold compared with a susceptible strain, whereas PxRdl1 expression was comparable among the resistant and susceptible strains. Collectively, our results indicate antagonistic effects of PxRDL1 and PxRDL2 on fipronil action in vivo and suggest that enhanced expression of fipronil‐resistant PxRdl2 is potentially a new mechanism of fipronil resistance in insects.
Slow and steady wins the race: contrasted phylogeographic signatures in two Alpine amphibians
Authors: DUFRESNES Christophe , RODRIGUES Nicolas , SAVARY Romain 
Published: January 2021

AbstractA deeper phylogeographic structure is expected for slow‐dispersing habitat specialists compared to widespread adaptable species, especially in topographically complex regions. We tested this classic assumption by comparing the genomic (RAD‐sequencing) phylogeographies of 2 amphibians inhabiting the Swiss Alps: the mobile, cosmopolitan common frog (Rana temporaria) against the stationary, mountain endemic Alpine salamander (Salamandra atra). Our results ran opposite of predictions: the frog displayed significantly higher genetic divergences and lower within‐population variation compared to the salamander. This implies a prominent role for their distinctive glacial histories in shaping intraspecific diversity and structure: diversification and recolonization from several circum‐Alpine micro‐refugia for the frog versus a single refugium for the salamander, potentially combined with better population connectivity and stability. These striking differences emphasize the great variability of phylogeographic responses to the Quaternary glaciations, hence the complexity to predict general patterns of genetic diversity at the regional scale, and the forces that underlie them.
Improvement of physicochemical properties of reduced‐cholesterol butter by the addition of β‐sitosteryl oleate
Authors: Nguyen Anh Thi Lan , Boakye Prince G. , Besong Samuel S. , Tomasula Peggy M. , Alamu‐Lumor Enyam S. 
Published: January 2021

AbstractBeta‐cyclodextrin (β‐CD) has been shown to successfully lower the cholesterol content of dairy products, such as butter, but the process tends to negatively impact the overall quality and consistency. In this study, β‐sitosterol, which is similar in structure as cholesterol, was reacted with oleic acid to form β‐sitosteryl oleate (BSO), and this was used to improve the consistency of reduced‐cholesterol butter. The reaction was catalyzed by sodium bisulfate (2%, w/w) at 140 °C, and the highest degree of esterification (94.3%) was obtained after 9 hr of reaction using a β‐sitosterol‐oleic acid molar ratio of 1:5. Ultra‐pasteurized cream was then treated with 15% (w/v) β‐CD at 40 °C with stirring (100 rpm), for 30 min. Results indicated a 95.4% reduction in cholesterol content. Finally, the reduced‐cholesterol cream was constituted to contain 3, 5, and 10% (w/w) BSO, after which fat was extracted from the three formulations and their melting profiles compared to that of milk fat. The cream containing 3% BSO showed a profile similar to milk fat and was, therefore, used to formulate BSO‐incorporated reduced‐cholesterol butter (BSOB). Instrumental analyses showed that BSOB was comparable to the control butter with respect to physical properties, such as hardness/firmness and adhesiveness.Practical ApplicationA modified plant sterol, beta‐sitosteryl oleate, was incorporated into a reduced‐cholesterol butter to improve its physicochemical properties. The reduced‐cholesterol butter was comparable to regular butter with respect to its consistency and melting properties and could be made into sticks. In addition to the reduced‐cholesterol butter, this product could provide the foundation for new products blending butter and oils to create other low‐cholesterol, reduced saturated‐fat products, possibly in stick form.
Inhibitory effect of caffeic acid on advanced glycation end product‐induced renal fibrosis in vitro: A potential therapeutic target
Authors: Jeon Gyeong Yun , Nam Mi‐Hyun , Lee Kwang‐Won 
Published: January 2021

AbstractAdvanced glycation end products (AGEs) are formed from amino acids and reducing sugars through nonenzymatic Maillard reaction. AGEs are known to induce oxidative stress, which may cause fibrosis or cancer. In this study, we investigated the protective effect of caffeic acid (CA) on AGE‐mediated kidney epithelial to mesenchymal transition (EMT) in human HK‐2 cells. Exposure to 100 µg/mL of AGEs by kidney epithelial cells raised the production of reactive oxygen species by 5.2‐fold and decreased levels of glutathione. In addition, cardamonin, a β‐catenin inhibitor, was used to determine the signaling pathway for β‐catenin in which cardamonin inhibited the AGEs‐induced translocation of β‐catenin into the nucleus, resulting in an inhibition of the EMT process. Similarly, our findings showed that, close to the control level, CA treatment decreased AGE‐mediated oxidative stress, loss of E‐cadherin expression, and overexpression of α‐smooth muscle actin and fibronectin by inactivation of the β‐catenin pathway. Furthermore, AGE treatment enhanced the expression of collagen type I (1.99‐fold) as well as the activity of metalloproteinases 2 (1.86‐fold) and 9 (2.79‐fold), but such increase was inhibited by the pretreatment of CA. In conclusion, this study determined the inhibitory effect of CA on AGE‐induced β‐catenin signaling, which prevented the occurrence of EMT in kidney epithelial cells. This suggests that CA may be a potential target for AGE‐induced renal fibrosis.Practical ApplicationExposure of kidney epithelial cells to advanced glycation end products (AGEs) leads to a rise in reactive oxygen species and a decrease in glutathione, thereby increasing oxidative stress that may cause fibrosis. However, treatment of kidney cells with caffeic acid (CA) prior to their exposure to AGEs lowers oxidative stress and decreases fibrosis. This research reveals the beneficial influence of CA on renal fibrosis in laboratory‐cultured kidney cells (in vitro), which makes CA a potential therapeutic target for AGE‐induced fibrosis.
Combination of natural strategies to improve the oxidative stability of echium seed oil
Authors: Roschel Gabriela Grassmann , da Silveira Tayse Ferreira Ferreira , Cajaíba Letícia Maeda , Ferrari Roseli Aparecida , Castro Inar Alves 
Published: January 2021

AbstractEchium seed oil is an alternative source of omega 3 fatty acids but it is highly susceptible to oxidation. A combination of three natural strategies was proposed in this study aiming to improve the oxidative stability of echium oil obtained by pressing (PO) or solvent extraction (PSO), kept in the storage condition for 180 days or during the consumption for 30 days. Our results showed that the reduction of temperature was sufficient to keep the oil stable during storage for both samples. During the consumption time, the best stability was achieved by adding a mixture of antioxidants, composed of sinapic (500 ppm), ascorbic (250 ppm), and citric (150 ppm) acids, and/or 20% of high oleic sunflower oil. The combined strategies promoted a 34 to 80% reduction of peroxide value and 0 to 85% reduction of malondialdehyde concentrations in the samples, showing to be a feasible and natural alternative to improve the oxidative stability of echium oil.Practical ApplicationOur study successfully applied an optimized combination of simple and low‐cost strategies to enhance the chemical stability of echium seed oil. As the use of echium oil expands around the world, the oil industry and final consumers may benefit from our results to increase the oil shelf‐life.