bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stanisław Majerski – autor projektów zakopiańskiej Księżówki
Authors: Podubny Bartosz 
Published: December 2021

Abstrakt:
Autor prezentuje nowe ustalenia dotyczące autorstwa budynku Księżówki w Zakopanem. W Żołyni, niewielkiej miejscowości w województwie podkarpackim, znajduje się Zbiór Dąbrowskich z Żołyni liczący kilka tysięcy projektów. Wśród nich autor odnalazł dzieła architekta Stanisława Majerskiego, m.in. projekty dla Księżówki w Zakopanem. Projekty dla tego obiektu, sygnowane także przez Majerskiego, odszukał również w Archiwum Narodowym w Krakowie. Analiza projektów wykazała, że wspomniany architekt był autorem murowanej części Księżówki. Jest to nowe ustalenie, ponieważ dotychczas budynek przypisywany był Eugeniuszowi Wesołowskiemu. Autor przedstawia także hipotezę, że powstała w okresie międzywojennym na miejscu dawnej Adasiówki drewniana część budynku również mogła zostać zrealizowana według projektu Stanisława Majerskiego.
Summary:
The Author presents new findings regarding the authorship of the ‘Księżówka’ building in Zakopane. Żołynia, a small town in the Subcarpathian Voivodeship, seats the Żołynia Dąbrowski Collection with several thousand projects, among which the author found the works of the architect Stanisław Majerski, including the projects of the ‘Księżówka’ in Zakopane. What is more, he found this object’s designs in the National Archives in Krakow, signed by Majerski as well. The analysis performed indicated the authorship of the above-mentioned architect pertaining to the brick part of the ‘Księżówka’, which is a new finding in this matter, because the building was previously attributed to Eugeniusz Wesołowski. The Author also presents a hypothesis stating that the wooden part of the building, erected during the interwar period on the site of the former ‘Adasiówka’, could also had been erected based on Stanisław Majerski’s design.
FEATURES OF MORPHOLOGICAL REARRANGEMENTS OF STRUCTURAL COMPONENTS IN THE RAT PINEAL GLAND UNDER THE IMPACT OF HEAVY METAL SALTS
Authors: Гринцова Natalia , Romanyuk Anatolii , Hodorova Ingrid , Karpenko Ludmila , Dmytruk Serhii , Bumeister Valentyna , Zaitseva Svitlana 
Published: December 2021

The development of the pathology of individual organs and systems undoubtedly depends on adverse environmental factors. Particular attention of researchers attracts heavy metal salts. Epiphyseal hormones play a key role in regulating and maintaining basic body functions. The article presents the results of the study on morphological and morphometric rearrangements of structural changes in the rat pineal gland influence for 30 days of heavy metal salts (sulfates of zinc, copper, iron, manganese, plumbers’ nitrite and chrome oxide). The selected concentration of salts in the mixture was due to the presence of similar concentrations of these salts in the soil and drinking water in some regions of Ukraine according to literature sources. General morphological and statistical research methods were used (histological, morphometric and variational statistics methods). The 30-days impact of the heavy metal salts combination on the rat body caused in the pineal gland morphological changes of nonspecific polymorphic nature, which were expressed in the increased vascular area, active glial response, hypertrophy of pinealocyte nuclei and increase of their optical density. Cytological signs in most pinealocytes indicated the predominance of indolamine synthesis over polypeptides. The main pathogenetic mechanisms of the influence of heavy metal salts on the organ have been established: change in the vascular lumen area, blood rheological properties impairment, tissue hypoxia, nucleus hypertrophy and change in their optical density. Morphological changes in the gland comply with the stress phase of the general adaptation syndrome. The above morphological changes negatively affected the processes of hormones evacuation into the blood, the course of the general adaptation syndrome and the homeostasis restoration in the organ.
ACUTE TOXICITY OF Β-KITIN EXTRACTED FROM THE SHELL OF BLUE SWIMMING CRAB (PORTUNUS PELAGICUS LINN.)
Authors: AMELIA RENNY , SAPTARINI NYI MEKAR , LEVITA JUTTI , SUMIWI SRI ADI 
Published: December 2021

Objective: This work aimed to study the acute toxicity of β-chitin extracted from crab shells in Bal b/c mice.
Method: The acute toxicity test was performed by following the OECD guidelines. Female mice were given single or divided doses of β-chitin (maximum 24 h) with doses of 500, 1000, 2000, 4000, and 6000 mg/kg of BW. Observations were made for 14 d, including behaviour, body weight, organ weight, and histopathology of vital organs (stomach, heart, liver, kidney, and lung).
Results: During 14 d, no deaths and no abnormalities in behaviour, bodyweight or organ weight were observed. Qualitative histopathological observations at the highest dose showed abnormalities of the liver and kidney compared to those of the control group. Nevertheless, the abnormalities did not affect the organ function.
Conclusion: This acute toxicity study reveals that β-chitin up to a dose of 6000 mg/kg of BW is not toxic, as proved by the normal behaviour, body weight, and vital organ weight of the animals. Further chronic toxicities study is needed to confirm its safety.
FORMULATION AND EFFECTIVITY OF THE ANTIOXIDANT GEL PREPARATION CONTAINING ZEAXANTHIN AS ANTI AGING
Authors: SETIAWAN FAJAR , NURDIANTI LUSI , SRI NENG 
Published: December 2021

Objective: This study was conducted to determine the IC50 value of zeaxanthin, to know the formula that meets the requirements of the results of physical evaluation of gel preparations, and to know the effectiveness of zeaxanthin gel as an anti-aging on the skin.
Methods: The preparation of this gel is made using zeaxanthin as an active substance with concentrations of 5%; 7.5%; and 10%. Tests conducted are organoleptic test, homogeneity test, pH, spreadability, viscosity, irritation test and cycling test. Tests conducted are organoleptic test, homogeneity test, pH, spreadability, viscosity, irritation test and cycling test. Tests on the effectiveness of zeaxanthin gel preparations against the backs of volunteers' hands were divided into 4 groups as well as testing conducted over 28 d.
Results: The results showed a value of IC50 zeaxanthin of 9.044 μg/ml, all gel preparations met the requirements of physical evaluation results except in cycling test and test results of the effectiveness of zeaxanthin gel preparations on the backs of volunteer hands there was an increase in humidity with an average increase of 33.17%±11.867 and wrinkles obedience with an average decrease of 47.466%±7.115.
Conclusion: Zeaxanthin can be formulated as gel anti-aging.
MOLECULAR DOCKING AND ADMET PREDICTION OF 5-BENZYLOXYTRYPTOPHAN AS A POTENTIAL RADIOPHARMACEUTICAL KIT FOR MOLECULAR IMAGING OF CANCER
Authors: IBRAHIM FAISAL MAULANA , HOLIK HOLIS ABDUL , HASIBUAN GHIFARI FARHAN , KARTAMIHARDJA ACHMAD HUSSEIN SUNDAWA 
Published: December 2021

Objective: This in silico study aims to determine the inhibition effect of 5-BOTP with various bifunctional chelating agents (BFCA); NOTA, DOTA, TETA, CTPA, H2CB-DO2A, H2CBTE2A against the antiporter site of the LAT1.
Methods: The research method consisted of the binding mode of 5-BOTP and its derivatives with LAT1, the docking score, the analysis of preADMET, and the overview of Ro5 compatibility.
Results: The results showed that 5-BOTP-NOTA and 5-BOTP-DOTA had interactions with the gating residue (Phe252, Trp257, Asn258, and Tyr259) on the antiporter site of LAT1. 5-BOTP-NOTA and 5-BOTP-DOTA affinity are around-11.50 and-9.14 kcal/mol, respectively.
Conclusion: Based on this study, 5-BOTP-NOTA and 5-BOTP-DOTA are the new compounds that have the potential as a theranostic agent of cancer by inhibiting LAT1.
Recopilación de técnicas ancestrales artesanales con potencial de innovación en sector textil, confección, diseño y moda en el departamento de córdoba Colombia.
Authors: Guzmán Martínez Karina del Carmen , Vallejo Calderón Jennifer , Sotelo Coronado Liliana Esther 
Published: December 2021

En el departamento de Córdoba existen empresas, diseñadores de modas y unidades productivas con necesidades insatisfechas, particularmente en la oferta de servicios especializados que complemente algunas actividades dentro de sus procesos productivos, que marquen la diferencia y les den valor agregado a sus productos. Los insumos artesanales, propios de la región, son un componente diferencial y que cubriría estas necesidades actuales, enmarcados en las políticas nacionales de apoyo al desarrollo local y a la dinamización de la economía naranja que apoya las industrias creativas y culturales. Por lo tanto, es necesario desarrollar actividades que contribuyan a fortalecer y preservar las técnicas ancestrales artesanales del departamento de Córdoba a través de insumos y/o complementos que enriquezcan el sector textil, confecciones, diseño y moda.

Lo anterior es posible mediante un proceso que permita indagar y consolidar la información relacionada con las técnicas ancestrales artesanales del departamento de Córdoba, identificando la Herencia de las Culturas Zenú y Embera Katio, lo cual conduciría a visualizar la amplia riqueza material cultural con la que cuenta el departamento de Córdoba, que podría ser utilizada en el sector textil, confecciones, diseño y moda a través de insumos y/o complementos de calidad, realizados por artesanos del departamento dinamizando así su economía familiar, contribuyendo al aprovechamiento de la riqueza cultural en el marco de la economía naranja y exaltando y promocionando la identidad cultural cordobesa.
Gamificación en Educación: Alternativa didáctiva en la adecuación de Diseños Pedagógicos para la formación
Authors: Medina Pérez Ruth Nadith , Ramirez Vanegas Leonardo Raúl Arcesio 
Published: December 2021

Objetivo: Este artículo de revisión busca identificar los conceptos y enfoques teóricos, la estructura y experiencias en el tema de Gamificación aplicada en educación, con el fin de ofrecer una aproximación que permita incorporar esta estragegia didáctica, en los diseños pedagógicos de Programas de Formación del SENA-CFTHS, y cualquier otro Centro de Formación. Materiales y métodos: Para dar cumplimiento al objetivo se diseña una revisión del estado del arte sobre el tema documentando información de fuente primaria de los últimos cinco años, dividiendo la investigación en una Fase Heurística y una Hermenéutica a partir de tres categorías de análisis: a) Conceptos y enfoques teóricos, b) Estructura en la gamificación, y c) Implementación de experiencias. Resultados y discusión: Gamificación es una estrategia basada en el aprendizaje significativo, constructivista y colaborativo, que contine componentes innovadores y motivadores. La complegidad de su estructura se basa en el desarrollo de la dinámica (narrativa/historia), la mecánica (reglas del juego) y componentes (herramientas de apoyo) que debe ser motivadora. Depende de la creatividad para su diseño pero no es necesariamente mediada por alta tecnología, por lo cual la estética es fundamental para que sea llamativa. Las experiencias de implementación han podido identificar un aumento en la motivación y cumplimiento autónomo de tareas y un ligero incremento en la capacidad de retención de temas. Para que su objetivo se cumpla debe estar ligada profundamente a los diseños curriculares y pedagígicos establecidos. Conclusiones: Se constituye como una estrategia apropiada para su implementación, pero requiere de espacios y tiempos adecuados de diseño y creación, en el los cuales debe participar un equipo ejecutor multidisciplinar.
Silences and Secrets of Family, Community and the State
Authors: Haukanes Haldis , Pine Frances 
Published: December 2021

In this article, we suggest that silence is often more about remembering than forgetting. We consider ways in which silences can occupy and dominate state discourse, community knowledge, family stories and individual narratives. Drawing on research material from Poland and the Czech Republic in the late socialist and post-socialist periods, we look at ways similar patterns of narrative fusion take place in various contexts in which both the public and the private domains are often shadowed by things veiled in secrecy and hidden from the general gaze. We argue that personal family and kin accounts of private things which for some reason cannot be spoken become entangled with, and to some extent communicated through, broader and more public historical narratives, and vice versa, and show how partial accounts are thus transmitted from generation to generation even while remaining largely unspoken. In developing our argument, we focus on the idea of walls of silence and on the process of drawingboundaries between people and the state, between generations (grandparents, parents and children) and between insiders and outsiders of communities. Suggesting that silence may be loud or quiet, we look at registers of silence and the ways in which they operate at the different levels of state, community and household. We ask what it means to hold certain kinds of knowledge, or to be excluded from these. At times, and for some people, knowledge may be a source of power or social or economic capital; for others, or in other contexts, being excluded from or rejecting knowledge, and thus not being privy to the subtexts of silence, may be a source or freedom and potential or possibility.
The establishment of the form of bullet morphology of fractures of the flat bones
Authors: Mykhailenko Oleksandr 
Published: December 2021

In the work were studied morphological features of bone tissue destruction, which may set the shape of the bullet. We considered problems of theoretical mechanics helped to explain the mechanism of formation of a perforated fractures of the flat bones from the effect of gunshot shells one - and doradca form. The proposed mechanisms allow to explain the difference in terms of destruction of bone tissue when exposed to fire shells one - and doradca forms, and as a consequence conduct a group identification form a firearm projectile according to the morphological characteristics of gunshot gunshot fractures of the flat bones.
The objects of the study there was an entrance gunshot gunshot fractures, which were formed from bullets one and Dorado form of the archival material Department of forensic crimaldi Kiev city clinical Bureau of forensic medical examination and obtained experimentally gunshot gunshot fractures of the flat bones. To assess the fracture mechanics of the flat bones, we used the data of theoretical mechanics. Justification of destruction of flat bones from the bullets odnorodno forms we considered for the problem Businesa, and destruction of flat bones from the bullets doradca forms on the example of the Hertz problem and model of hill-Johnson. The results obtained were processed by methods of variation statistics.
Welcome to the final issue of the Journal for 2021
Authors: Fong Neale 
Published: December 2021

It has been another extraordinary year for the health system and its leaders across the globe as the pandemic wrought unplanned and unplotted transformation. It seems apparent that the pace of change is with us to stay and casting forward in 2022, we can expect more challenges as we grapple with some of the unknowns of living with Covid.
As health leaders, managers and executives, we are extremely aware that we step forward to “living with COVID” with an exhausted workforce, a potential tsunami of demand on our own mental health care capabilities, and indeed the demand from all those previously usual activities that have been left untended in the past two years. It is in these times that we must lead with compassion – the need for empathic, caring leadership has never been greater. I hope, too, that we understand that we are not alone and that it is the support of our peers that will make this journey forward a little bit easier.
Utilization of Renewable Energy (Solar, Wind) for Power Generating Systems -A Review
Authors: Parveen Khashiya , Vishwakarma Prof. Shravan 
Published: December 2021

As it is known to that energy resources are limited to an extent thus to fulfil the desire of the development in modernization, it is necessary to utilize renewable energy resources which can result in generation of powers and used further in different fields. In the current scenario, wide range of wind or solar hybrid system is playing vital role in the process of development. In this review paper we have discussed about the work done by several researchers in developing the systems for generating power by wind or solar renewable energy. Numerous of researchers have worked in the field of power generator systems with the utilization of renewable energies as feed.
Pengembangan LKPD Berorientasi Guided Discovery Learning dengan Internet Assisted Learning untuk Melatihkan Keterampilan Berpikir Kritis
Authors: Zakiyah Farhati , Yonata Bertha 
Published: December 2021

This study aims to describe the feasibility of a guided discovery learning oriented Student Worksheet to train critical thinking skills on reaction rate materials. The feasibility of this student worksheet is reviewed from three aspects those are validity, practicality, and effectiveness. The research method used was Research & Development (R&D) which was tested on 10 students of class XI IPA MAA Al-Amiriyyah. The results showed that the student worksheet was declared worthy in term of the validity aspect with the validity of the content reviewed from the criteria of conformity with the material and basic competencies,those are conformity with the guided discovery learning component, conformity with the critical thinking skills component and the suitability of practicum video with reaction rate factors of 100%, 89%, 83% and 91% respectively, and the validity of the constructs reviewed from the language criteria and presentation respectively obtained results of 90% and 91% respectively. , this percentage decrease is described as very valid. Practicality obtained the results of average observation of student activities by 98.51% and the response of learners on the criteria of content, language and presentation obtained results of 91%, 97% and 89% respectively. All three criteria are described as excellent. Effectiveness based on increased pretest-posttest results of critical thinking skills of learners who obtained a 100% completion percentage with an n-gain score in the range of 0.69-0.88 with medium to high categories
Pengembangan Media Pembelajaran Kimia Berbasis Android Pada Materi Termokimia Kelas XI SMA
Authors: Donasari A'in , Silaban Ramlan 
Published: December 2021

The aim of this research was to know the feasibility and student learning outcomes of chemistry learning media based on android. This research is a type of research and development which is adapted from the ADDIE Analysis, Design, Development Implementation model. The media developed was tested on 30 students of class XI IPA RK Serdang Murni Lubuk Pakam Private High School. The data was collected through the expert validation sheet of student learning outcomes. The data analysis technique used quantitative and qualitative data analysis. The results of the research and the development concluded that: (1) Android-based chemistry learning media for class XI IPA students in this thermochemical material was developed with a 4D model and designed in the form of an application in the form of an android studio with the java programming language. (2) Android-based chemistry learning media for class XI Senior high school’s students have been declared eligible (valid) to be used in thermochemical learning. Eligibility (validity) of Android-based chemistry learning media for high school students of class XI, is found qualitatively based on the evaluation of material expert validators and media experts in terms of the feasibility of content, presentation, language and graphics according to BSNP with a mean of 4.04. (3) Based on the learning outcomes of students who are taught using Android-based chemistry learning media, it is not the same with the KKM value (75) based on the obtained mean of 90.17 with the highest value of 100 and the lowest score of 80.Thus, Android-based chemistry learning media in thermochemical is suitable for school use.
PROTOTYPE JEMURAN PINTAR PENDETEKSI HUJAN DENGAN MENGGUNAKAN MICKROKONTROLER ATMEGA2560 BERBASIS WEBSITE
Authors: Adianto Bayu , Fiati Rina , Latubessy Anastasya 
Published: December 2021

Pada musim hujan masyarakat, khususnya kaum ibu merasa khawatir ketika menjemur pakaian. Kekhawatiran itu bukan tanpa alasan, sebab ketika bepergian para ibu meninggalkan jemuran di rumah dalam keadaan belum kering. Pada saat bersamaan, keadaan rumah mereka dalam keadaan kosong karena semua penghuni rumah melakukan aktivitas masing-masing di luar rumah. Kekhawatiran yang sering muncul adalah jikalau hujan tiba-tiba turun dan di rumah tidak ada orang, maka pakaian yang dijemur akan kembali basah dan berpotensi memunculkan bau tidak sedap pada pakaian. Sehingga penulis berinisatif membuat jemuran otomatis yang dapat membuat pakaian yang dijemur tidak kehujanan Jemuran pintar ini di buat melalui tiga tahapan bagian input, proses, dan output. Bagian input terdapat sensor hujan untuk mendeteksi air, sensor suhu untuk mengukur suhu sekitar, sensor cahaya mendeteksi sensifitas cahaya yang nantinya sensor-sensor tersebut berguna sebagai alat pendeteksi dalam mengangkut dan mengeluarkan jemuran ke dalam rumah. Kemudian data di proses oleh Arduino atmega2560. Setelah proses selesai sistem akan menghasilkan keluaran atau output yaitu menarik dan mengelu arkan jemuran sesuai dengan perintah dari sensor lalu hasil data informasi cuaca yang dihasilkan oleh alat ini dikirimkan ke website melalui Node Mcu. Tujuan dari diciptakannya alat tersebut adalah agar memudahkan dalam mengangkut dan mengeluarkan jemuran ketika waktu hujan. Hasil yang yang diharapkan dari penelitian ini adalah menghemat tenaga manusia, dengan menggunakan sensor hujan dan sensor cahaya dalam menggerakan mesin pada jemuran otomatis. Memanfatakan sensor suhu dalam mengukur kelembapan sekitar rumah sehingga memudahkan masyarakat dalam monitoring dari jarak jauh melalui website apabila terjadi hujan maupun cuaca sedang cerah.