bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anti-human lung cancer activities and survey
of glutathione reductase and glutathione S transferase
inhibition properties with molecular modeling studies
of 2′-hydroxy-5′-methyl-3′-nitroacetophenone:
a pre-clinical trial study
Authors: Dou Yawei , Lv Shanshan , El-kott Attalla F. , El-kenawy Ayman E. 
Published: May 2021

IntroductionThe molecular docking method was found to calculate the biological activity of the 2′-hydroxy-5′-methyl-3′-nitroacetophenone (2′-H-5′-
M-3′-N) molecule against the enzymes studied.Material and methodsIn these calculations, the enzymes used were glutathione reductase (GR) and glutathione S-transferase (GT). After the modeling calculations were completed, the ADME/T parameters were examined
to calculate the future drug use properties of the 2′-H-5′-M-3′-N molecule.
To survey the antioxidant properties of 2′-H-5′-M-3′-N, the DPPH test was
used. Several human lung adenocarcinoma cell lines, i.e., lung moderately
differentiated adenocarcinoma (LC-2/ad), lung poorly differentiated adenocarcinoma (PC-14), and lung well-differentiated bronchogenic adenocarcinoma (HLC-1) cell lines, were used to determine the anticancer properties
of the molecule.ResultsCell viability of 2′-H-5′-M-3′-N was very low against PC-14, LC-2/ad,
and HLC-1 cell lines without any cytotoxicity towards the normal cell line.
The IC50 values of 2′-H-5′-M-3′-N against LC-2/ad, PC-14, and HLC-1 cell lines
were 475, 250, and 691 µg/ml, respectively. The best anti-human lung cancer properties of 2′-H-5′-M-3′-N against the above cell lines were observed
in the case of the PC-14 cell line.Conclusions2′-H-5′-M-3′-N was found to have significant antioxidant and
anti-human lung cancer properties. It appears that the anti-human lung carcinoma effect of 2′-H-5′-M-3′-N is due to its antioxidant effects.
Introduction
Authors: Wain Debra , Saward Melanie 
Published: May 2021

The scholars who present their work here in this Special Issue on Writing Through Things: Past and Broken Things were invited to contribute their research in the form of a traditional article or creative work that explores the fission between the arena of the mind and the concrete, tangible things of the world around us; to explore that ‘unexplored world’ of ‘memory, emotion, and untapped creativity’ (Pollack, 2011: 230). The events of 2020, lockdowns and self-isolating, meant that we were, perhaps more than ever, surrounded by our own things, offering an opportunity to see these things differently and maybe more clearly. Bill Brown explains that “the work being done… under thing theory is addressing how it is that the inanimate object world helps to form and transform human beings. Part of that is to say: how does our material environment shape us?” (Brown, 2012). We, as writers and researchers, are concerned with that which forms and transforms us and the world around us. These catalysts of formation and transformation can be people, experiences, landscapes, and sometimes they can be the seemingly everyday objects that surround us. As Brown points out, the things that impact on us do not have to be those of ‘economic value in Marxist terms’; they can be ‘small things’ of ‘symbolic value’ (Brown, 2012).
delete - ‘Every woman adores a fascist’ - delete : Feminist literary intervention in elegiac writing
Authors: Watts Rachel 
Published: May 2021

This article is a fictocritical intervention in the patriarchal form of the elegy and a reflection on the expression of grief, anger and subjectivity by women writers. It uses Adrienne Rich’s writing on women’s self-destruction as a feminist methodological framework to explore two specific ideas. First, how we speak of the dead, which concerns the agency, subjectivity and anger with which we express our remembrance and our grief, and second, literary style and feminist interventions in the elegiac form. Taking a fictocritical approach, the article combines the objective style of the academic mode with a subjective treatment, resulting in a cut-up text that combines analysis and my own reflections. In this, the article is informed by work by Anna Gibbs (1998; 2005) and Ross Watkins (2014). This multivocal approach aims to answer the question: how does the approach to the elegy form employed by Virginia Woolf and Sylvia Plath enable a nuanced representation of grief, mourning and agency, and how can other women writers build on this approach to write to and through each other in the context of a patriarchal literary tradition?
Macbeth of Kelantan
Authors: Sun Emily 
Published: May 2021

‘Macbeth of Kelantan’ is an accompanying piece to ’How to Read Shakespeare in the Post-Atomic Age’, a paper that I presented at the 2018 AAWP conference. Both short stories use Pierre Bourdieu’s cultural capital theory as a point of departure to untangle the complexities of how individuals assign different values to various reading practices in situated contexts. Both stories draw on key themes that emerged from a small qualitative study which examined the cultural capital of reading. While ‘How to Read’ examines the value assigned to reading canonical literature across generations, ‘Macbeth of Kelantan’ explores how the value of reading practices are negotiated across fields.
Advanced diarology: mortification, materiality and meaning-making
Authors: Taylor Stayci , Munro Kim , Murray Peta 
Published: May 2021

Public diary-reading events, arguably originating in the USA in 2002, continue to draw participants eager to share their teenage angst and juvenilia, yet there is little scholarly reflection on this peripheral practice of performative writing. Having birthed our own version in 2017 – within the safe harbour of the academy and using an intuitive, practice-based methodology – we believe there are some useful questions to pose about the autoethnographic contributions of this mortification rite. Eighteen months in, we are further moved to ask, what is happening in the presentational and performative space as we show our younger selves to one another as we have, and do? This article, a follow-up to our previous Diarology for beginners (2019), formally reiterates on the page the associative leaps and communal meaning-making arising from our explorations so far. Prompted by questions, such as, ’Is the practice of diary keeping inherently gendered? Is it about becoming visible? Audible? Memorable? What? And what is the impulse to publicly share the archives?’ (Munro, Murray and Taylor 2019), we draw on the literature around diary keeping, as well as theories on voice, gender and creative autoethnography, as a way into understanding diary performing and the public sharing of juvenile shame.
Anxieties of obsolescence and transformation: digital technology in contemporary Australian literary fiction
Authors: Novitz Julian 
Published: May 2021

When addressing the rise of mass media, literary authors of the late twentieth century often expressed an ‘anxiety of obsolescence’ (Fitzpatrick 2006) in their work: an acute awareness of being potentially displaced. This often led them to adopt an attitude of defiance in the face of technological change. Many contemporary literary authors adopt a similar oppositional attitude towards the rise and encroachment of networked technology, but retreating to the increasingly peripheral territory of ‘pure’ print-based literature is no longer easy. Digital technology presents not only the possibility of displacement but also that of transformation, with its spread threatening to fundamentally alter the practice of reading and writing. Possibly in response to the radical upheavals faced by Australian literary culture due to the rise of electronic publishing since 2012, recent works by three established Australian authors – Amnesia by Peter Carey (2014), the Wisdom Tree novella sequence by Nick Earls (2016), and The Life to Come by Michelle de Kretser (2017) – examine the ways in which networked technologies challenge or complicate the role, identity and practice of the contemporary print-oriented writer. The telling connection is that they present the relationship between print-based writers and networked technology as being transformative rather than simply oppositional, demonstrating the emergence of complex and nuanced responses to the rise of networked technology in Australian literature.
‘Much of a muchness’
Authors: Prendergast Julia 
Published: May 2021

James is a weirdo – a dirty little weasel. He’s Gene’s grandson, he’s blood, but she stakes no claim. Without warning, he throws the cat in the spit roast. It’s a horrible mess. The cat’s torso thwacks against the drum of the spit and her underbelly is singed bare. Her front paws land in the coals
Embodied Ecumenical Eco-spirituality: Revised Christian Attitudes Toward the Creation
Authors: Skjoldager-Nielsen Kim 
Published: May 2021

ABSTRACT
This article argues that what is currently perceived as an ecological turn in Christian theology is actually a re-turn to ancient beliefs going back at least one thousand years. These eco-theologies lend themselves in embodied ways to the fight against climate change. To prove its point, this essay does a literary study of selected texts by prominent theologians' and thinkers' ecologies. To establish an equity among female and male theologists, this essay has chosen two women and two men. To obtain some geographical diversity, it includes one North American, one Swede, one German, and one Latin American; two are Catholic, two are Protestant. They are brought together across space and time in an ecumenical dialogue. They are Hildegard von Bingen, Olov Hartman, Pope Francis, and Sallie McFague. Applying theatricality and performativity, in combination with Hjalmar Sundén's psychological role-playing theory and understanding of worship- and spirituality-driven identity-formation as the basis for an embodied ecumenical eco-spiritual program. At the end of the article, this program is outlined.
Does Faith Dismiss Performance? Observations on the Cult of Muthappan in Northern Kerala
Authors: Pereira Filipe 
Published: May 2021

ABSTRACT
A living god from North Kerala, Muthappan attracts a wide range of Hindu believers, mostly due to his unconventionality and transgressiveness. But the large masses of followers, seeking individual blessings to satisfy their faith, induce deviations in the ritual sequence, especially to its length, which acts against the establishment of a liminal condition, the attainment of flow, and the achievement of communitas. In addition, the new devotees worship the teyyam at home according to models of Brahmanical temple ceremonies, thus jeopardizing the specificity—and anti-structural character—of the teyyam tradition. In both situations, faith, and an increased religious fervor, seem to act against the performance of the ritual.
Ritual, Community Preservation, and Environment in Theyyam Performance
Authors: Madathil Sathyabhama 
Published: May 2021

ABSTRACT
Theyyam is a uniquely pantheistic art form, and its performance has endured the threat of environmental change and cultural displacement. The perspectives of Theyyam performers has undergone a paradigm shift in recent years. Theyyam artists today are compelled to perform in a way that is not limited to local spaces but that can reach more mainstream audiences. The COVID-19 pandemic, too, has had an adverse economic impact on performers, whose principal livelihood is farming. Hence, contemporary performers have been seeking variations of practice that do not give up Theyyam's sociocultural essence.
The Ethical Conundrum of a Jewish and Democratic State
Authors: Ellenson David 
Published: May 2021

Abstract
Critics charge that the humanistic views expressed by the founders of Israel through its Declaration of Independence have been diminished and that an antidemocratic virus has taken root in the State in recent years. Examination of Megillat Ha'atzmaut, the Israeli Declaration of Independence; the debates that swirled around it at the formation of the state; and the concurrent views of Rabbi Isaac Halevi Herzog on the issue of Israel as a democratic state reveals that these disagreements about the character of Israel as being both “Jewish and democratic” are rooted in ideological positions present in Israel's first years. A failure to resolve them so that democratic values can be affirmed remains an ongoing challenge to the nation.
Theological Hermeneutics, Exegesis, and J. R. Daniel Kirk’s A Man Attested by God
Authors: Leim Joshua 
Published: May 2021

ABSTRACT
J. R. Daniel Kirk’s book A Man Attested by God attempts to undermine recent arguments for “early high Christology” in general and “divine” Christology in the synoptics more particularly. This essay judges Kirk’s study to obscure the narrative Christologies of the Synoptics more than it illumines them, exhibiting the pitfalls of exegesis inattentive to three interrelated disciplines: recent hermeneutical developments, literary and historical details in the texts under discussion, and the church’s precise theological grammar.
Hebrews as Participatory Exegesis
Authors: Ribbens Benjamin J. 
Published: May 2021

ABSTRACT
Matthew Levering and Hans Boersma have outlined participatory or sacramental exegesis as the approach the church fathers used to interpret Scripture, in particular to interpret the Old Testament in light of the New Testament. This article summarizes sacramental exegesis and then explores how Hebrews interprets the Old Testament in a similar way, viewing Old Testament events and people as sacramenta to the New Testament reality (res). Using Hebrews’ discussion of sacrifice, rest, and sonship as examples, the article demonstrates how Hebrews shares the same interpretive patterns as sacramental exegesis and how participatory readings of Hebrews have interpretive power to resolve tensions existing in contemporary Hebrews scholarship.
Between Service and Scripture: A Qualitative Study of Missional Hermeneutics
Authors: Mckinzie Greg , Cevallos Carlos , Ramirez-Johnson Johnny 
Published: May 2021

ABSTRACT
Using a qualitative research method known as narrative inquiry, the authors undertake an exercise in empirical hermeneutics in a Latino church context in order to explore the formative effects of participation in mission on biblical interpreters. The analysis leads to the construction of a twofold hermeneutical model that provisionally answers our research question: the relationship between participants’ experiences of mission and their understandings of the Bible seems to consist of dynamics designated as missional emplotment and narrative fusion.
Prevalence of Cannabinoid Use in Patients With Hip and Knee Osteoarthritis
Authors: Deckey David G. , Lara Nina J. , Gulbrandsen Matthew T. , Hassebrock Jeffrey D. , Spangehl Mark J. , Bingham Joshua S. 
Published: May 2021

Introduction:
State legalization and widespread marketing efforts have increased the accessibility and consumption of off-label, non–FDA-approved, cannabinoid (CBD) products. Although clinical evidence is largely absent for the treatment of musculoskeletal pain, patients are experimenting with these products in efforts to relieve joint pain. Assessment of the prevalence, perceived efficacy compared with other nonsurgical modalities, and usage patterns is warranted. The purpose of this study was to report the prevalence and perceived self-efficacy of CBD products in patients with symptomatic hip and/or knee osteoarthritis (OA).

Methods:
Two-hundred consecutive patients presenting with painful hip or knee OA were surveyed at their initial evaluation at a large academic center. Using Single Assessment Numeric Evaluation (SANE) scores, survey questions assessed perceived pain and effectiveness of CBD products, in addition to other nonsurgical treatment modalities. Chart review provided demographic factors. Descriptive statistics were used to characterize the data.

Results:
Of the 200 patients (80 hip OA, 108 knee OA, and 12 both), 66% were female, and average age was 67 years (range 36 to 89 years). Twenty-four percent (48/200) of patients endorsed use of CBD products before their presentation. The average presenting SANE score (range 0 to 100) for non-CBD users was 50.8 compared with 41.3 among CBD users (P = 0.012). Sixty percent of patients learned about CBD through friends, and 67% purchased CBD directly from a dispensary. Oral tinctures (43%) and topical applications (36%) were the most commonly used forms. In addition, 8% of participants in this study had tried marijuana for their pain.

Conclusion:
A 24% incidence of CBD usage was found among patients presenting with hip or knee OA. No significant perceived benefit of CBD use seems to exist compared with its nonuse, as patients who used CBD reported significantly worse SANE and visual analogue scale scores than nonusers at baseline. Follow-up studies are warranted to assess these findings.
Rice: Worldwide Production, Utilization, Problems Occurring Due to Climate Changes and Their Mitigating Strategies
Authors: Ikram Muhammad , Haseeb-Ur-Rehman  
Published: May 2021

The production of rice is least in Pakistan and quite low as compared with other countries. Proper crop management techniques such as intercropping and combining organic manures are useful for better productivity and eco-friendly environment. Whereas studies are needed to evaluate the efficiency of intercrops and incorporation of certain nutrients with these plants. To examine results of intercropping experiment was carried out research by combining nutrient management practices. Five methods were taken including, sole rice, sole Green gram, rice + Green gram (drill), rice + green gram (Ridges), rice + green gram (bed) in the main plot moreover sub-plot included treatments of organic and inorganic supplement. The results show that sole rice followed by intercropping rice along green gram (poultry manure) has better characteristics of growth and yield, higher yield.by changing irrigation methods and farming methods, managing organic additives and fertilizer inputs, and choosing appropriate varieties and planting methods.CH4 decreased by 75% and N2O increased by 58%. The overall rice production of Rice + green gram(ridges) is 2285 kg ha−1 followed by rice + green gram(drill) (2060 kg ha−1). Rice + green gram(ridges) intercropping and (25 percent Urea+25 percent FYM+ 50 percent PM) were also correlated with better N usage performance and post-harvest soil usable N, phosphorus (P) and potassium (K) Benefit: cost (BC) ratios were also higher in the same treatment. From these results it is obvious that the integration of intercropping and induction of organic manures has a substantial impact on the outcome of rice.
Counseling Sexually Abused Children: Lessons from Ghana and Zambia
Authors: Agordzo Edoh-Torgah Nyuiemedi , Matafwala Marien 
Published: May 2021

The scourge of child sexual abuse has been on the increase world over, Ghana and Zambia inclusive with millions of children being sexually abused every year at a global prevalence rate of 34.4%. Using the qualitative narrative approach, the interview guide was used to gather data purposively from 112 participants made up of 40 Domestic Violence and Victims Support Unit officers, 32 parents and 40 victims aged 8–17 years who reported their abuse at 15 police stations across Central Region and Lusaka Province of Ghana and Zambia respectively. Data were thematically analyzed. The study found among others that children in both countries received safety nets and pieces of advice on legal and medical procedures. It also found that some victims expressed happiness at their abuses being reported and heard. However, lack of professional counseling training and power imbalances inhibit the police officers’ efforts. The study concludes that though officers use some skills and provide a kind of trauma counseling more is needed in the areas of individual and group therapy for comprehensive and effective counseling. Skills such as encouragement, assertiveness, and re-assurance can lead to disclosure, prevent future sexual abuse, reduce anxiety and fear, promote healing and empowerment. When children receive adequate counseling immediately after abuse they do immediate damage repair both of their psychological and social “self”. The study recommends training in counseling for the officers in both countries for effective counseling of abused individuals. Additionally, officers should be linked with professional counsellors at universities to refer abuse cases for treatment.
Biological Determinants of Hostility
Authors: V. Gafarov Valery , A. Gromova Elena , N. Maksimov Vladimir , V. Gagulin Igor , V. Gafarova Almira 
Published: May 2021

Our aim was to study the association of hostility with the DRD4, DAT, MAOA genes in an open male population of 25–64 years old. A representative sample of men aged 25–64 years (n = 657 men, average age 44.3 ± 0.4 years) was examined in 1994–1995 and 45–64 years old (n = 781 men, average age - 56.48 ± 0.2 years) in 2003–2005 using the methods proposed by the WHO international program “MONICA-psychosocial” and “HAPIEE”. All respondents completed the hostility questionnaire on their own. Genotyping of the DRD4, DAT and MAOA gene polymorphisms was carried out. It was established that the level of hostility in the male population was 76.9% in the group of 25–64 years old and 60.3% in the group of 45–64 years old. Genotypes 4/6, 4/7 of the DRD4 gene are reliably associated with a high level of hostility; the genotype 4/4 of the DRD4 gene is associated with an average and lower level of hostility. There was no association of individual genotypes and VNTR alleles of DAT gene polymorphism with different levels of hostility. It was found that among individuals with low-active alleles of the MAOA-L gene (alleles 2 and 3), a high level of hostility was more common - 50.9%. The results of constructing a logistic regression model showed that the presence of low-active alleles (2; 3) of the MAOA gene increases the likelihood of hostility OR = 2.103 (95% CI 1.137–3.889, p = 0.018). Based on the received data we can assume that the long alleles of the DRD4 gene and the low-level allele of the MAOA-L gene are associated with hostility.
Clinical and laboratory characterization of adult T-cell leukemia/lymphoma in patients from Salvador, Bahia
Authors: Bomfim Evelyn Keila dos Santos , Santos Mariane Melo dos , Freire Songeli Menezes , Meyer Roberto José , Torres Alex José Leite 
Published: May 2021

ABSTRACTATLL is a malignant and aggressive leukemia whose survival time is limited. It is known that 5% of individuals infected with HTLV-1, after many years of latency, may develop this disease. The mechanisms by which the evolution of clinical conditions occurs are unknown, and in Brazil there are few studies about ATLL, this some important themes will be addressed in this study. Thus, the objective of this study is to characterize the epidemiological and immunophenotypic profile of patients diagnosed with ATLL, attended at an oncohematological reference center in Salvador, Bahia, in the period between 2010-2018. The methodology consisted of a descriptive, retrospective of time series study, which cases of ATLL were collected from reports belonging a reference laboratory and of medical reports available from Com-HUPES. These data were treated and analyzed statistically, being observed that the majority of cases were female and that a large part have the most aggressive clinical condition Although the literature reports that ATLL clinical condition are always considered as severe, in this study it was observed that patients can achieve long survival in good clinical conditions, according to the treatment administered. In view of the available results, it is possible to conclude that exist a broad distinction between the clinical and molecular forms, being may be an important indicator of the evolution of ATLL.