bluuebunny/crossref_metadata_2025_split huggingface dataset:
Consumers’ Perceptions of Price Steering in Shopping Online for Tourism
Authors: CHAPUIS Jean Michel 
Published: July 2021

When confronting discriminations during the buying process, the consumers may perceive unfair transactions and some untrustworthy providers. Price steering is a common manipulation of listing offers tailored to a customer’s request. The consumers receive a same-products list in a different order for the same query on e-shop. The study questions whether its performance is related to discrimination among consumers. This paper mobilizes the theory of Justice to explore perceptions of fairness and trust in the practice of price steering. The proposed framework states that the post-purchase stage reveals perceptions intervening in the effect of price steering on willingness to pay.An experiment with a total 883 respondents is simulating an online shopping. The list of options shown online is manipulated. This study documents the main effect of price steering such as a higher willingness to pay and driving online purchasers toward certain choices. This effect is found to generate up to 20% of extra revenue. The analysis also finds a negative influence on perceptions with no difference between the discriminated segments of the market. Implications for researchers and managers: the pricing schemes should be carefully tailored to maintain fairness, as well as profitability, by considering rate parity across online channels and purchasing experiences.
Still Life
Authors: Backman Rogers Anna 
Published: July 2021

There is indeed a "miracle" in the 1970 film Wanda. This film has survived, despite decades of neglect, to emerge into the fuliginous light of an era that may just be ready to strain at grasping its harsh and brutal truths -- truths that reveal the imbrication of the psychic in the social and the experiential in political structures. Barbara Loden's film dares to suggest that the social and ethical functions of art should not necessarily be redemptive – that salvation is a cheap and spurious form of consolation that few can afford in this world. This film, made by a woman who knew all too well what it means to be defined through and by her material circumstances (and her relationships to men), and that is so relentlessly ferocious in its refusal to assuage and comfort the viewer, has always been a form of future feminism. Wanda does not brook the comforts of positivity, of aspiration, or even the luxury of selfhood.
This film, Still Life contends, is so radical in its feminist-anti-capitalist politics of refusal that we are still struggling to keep up with it. It delineates precisely how the personal is political and why this matters now more than ever. Wanda, a film about a woman who refuses to be saved or to save herself, who lacks the means and energy to alter anything in her life, who lives in a permanent state of blockage, impasse and failure is, as this publication suggests, the film of our contemporary moment.
CONTRIBUȚII ALE EDUCAȚIEI FIZICE ȘI SPORTULUI LA ÎNDEPLINIREA OBIECTIVELOR AGENDEI 2030 A ONU PENTRU DEZVOLTARE DURABILĂ
Authors: ISTRATE Marius Constantin 
Published: July 2021

Articolul prezintă, într-o manieră succintă, cele 17 obiective prioritare ale Organizației Națiunilor Unite privitoare la dezvoltarea durabilă, cuprinse în Agenda 2030. Aceste obiective se referă la conservarea planetei, la grija față de ecosistemele acesteia și la creșterea calității vieții locuitorilor de pe întreg mapamondul.
Pe lângă abordarea sistematizată a obiectivelor Agendei 2030, articolul reliefează legătura educației fizice și sportului cu posibilitățile de dezvoltare ale societății din alte domenii, astfel încât teoria să se poată materializa în practică. Prezentarea lor în paralel, în acest format este o motivație suficient de puternică, pentru a atrage atenția asupra domeniului de interes și pentru a-l înțelege mult mai profund, și demonstrează că educația fizică și sportul reprezintă un sistem complex de valori, mijloace specifice și valențe, care, puse în valoare în mod corespunzător și utilizate într-un mod ingenios, devin căi viabile în realizarea celor 17 obiective de dezvoltare durabilă.
Mepolizumab decreased the levels of serum galectin-10 and eosinophil cationic protein in asthma
Authors: Kobayashi Konomi , Nagase Hiroyuki , Sugimoto Naoya , Yamamoto Shiho , Tanaka Akihiko , Fukunaga Koichi , Atsuta Ryo , Tagaya Etsuko , Hojo Masayuki , Gon Yasuhiro 
Published: July 2021

Background
Mepolizumab, a humanized antibody targeting interleukin-5, decreases the number of blood eosinophils and the frequency of exacerbation of severe asthma. Galectin-10 is a protein within the cytoplasm of eosinophils and constitutes Charcot-Leyden crystals, which promotes key features of asthma. However, the relationship between time kinetics and clinical response of eosinophil-derived molecules such as galectin-10 or eosinophil cationic protein (ECP) has not been precisely investigated.

Objective
This study aimed to clarify the precise time course of the levels of serum galectin-10 and ECP after mepolizumab treatment and to analyze the relationship between the levels of eosinophil-derived molecules and the clinical background or response to mepolizumab treatment.

Methods
This multicenter, prospective open-label study recruited 20 patients with severe eosinophilic asthma. Mepolizumab was administered every 4 weeks for 32 weeks and the levels of various biomarkers were serially analyzed.

Results
The serum galectin-10 and ECP significantly and rapidly decreased 4 weeks after initial administration of mepolizumab. In contrast, basophil count, fractional exhaled nitric oxide, and the serum total IgE level were unchanged during treatment. Asthma Control Questionnaire-5, Asthma Health Questionnaire-33, and Lund-Mackay scores significantly improved after mepolizumab treatment. Both high ECP and eosinophil count related to better response in forced expiratory volume in 1 second (FEV1) and measurable ECP level at 4 weeks after administration of mepolizumab related to the further improvement in FEV1 toward week 32. No significant difference in improvement in FEV1 was observed in galectin-10 high group. The level of ECP at baseline was significantly related to the higher prevalence of nasal polyp and Lund-Mackay score.

Conclusion
This study was the first to show that the levels of serum galectin-10 decreases after initial administration of mepolizumab. The significant relationship between serum ECP and better response in FEV1 suggested the potential role of serum ECP as a predictive biomarker for the efficacy of mepolizumab (UMIN000030466).
Clinical evaluation of rush immunotherapy using house dust mite allergen in Japanese asthmatics
Authors: Uchida Takahiro , Nakagome Kazuyuki , Iemura Hidetoshi , Naito Erika , Miyauchi Sachiko , Uchida Yoshitaka , Soma Tomoyuki , Nagata Makoto 
Published: July 2021

Background
Allergen immunotherapy (AIT) is a specific treatment of administering clinically important allergens to patients who have allergic diseases. In Japan, the standardized house dust mite (HDM) allergen for subcutaneous immunotherapy (SCIT) was approved in 2015, and we then introduced rush-immunotherapy (rush-IT) using the standardized HDM allergen for HDM-sensitive asthmatics. However, little data are available on the safety and effectiveness of rush-HDM-IT, especially for Japanese asthmatics.

Objective
The objective of this study was to examine the safety and clinical effectiveness of rush-IT using the standardized HDM for HDM-sensitive Japanese asthmatics.

Methods
Thirteen HDM-sensitive asthmatics who received rush-HDM-IT and 12 HDM-sensitive asthmatic controls were enrolled. To evaluate the safety, the number of systemic reaction (SR) events, including anaphylaxis, was assessed. To evaluate the effectiveness, changes in the treatment step, dose of inhaled corticosteroid, and asthma control after rush-HDM-IT and the subsequent maintenance SCIT were assessed. Changes in the HDM-induced production of type 2 cytokines from peripheral blood mononuclear cells were also evaluated.

Results
Among the 12 patients who received rush-IT, 4 (30.7%) experienced a SR and 3 (23.1%) experienced anaphylaxis. However, the anaphylaxis was not severe (grade 3) in all cases, and they recovered in a short time. The treatment step of asthma was better and the dose of inhaled corticosteroid was lower in the rush-HDM-IT group than in the control group. The HDM-induced production of both interleukin (IL)-5 and IL-13 from peripheral blood mononuclear cells was significantly lower in the rush-HDM-IT group than in the control group.

Conclusion
Rush-HDM-IT can be performed relatively safely in Japanese asthmatics. Furthermore, rush-HDM-IT and the subsequent maintenance SCIT provided clinical improvement in asthma patients, and was accompanied by the suppression of HDM-specific Th2-mediated systemic immune responses.
De raadsheer-commissaris in het enquêterecht
Authors: Soerjatin E.M. , Kruse C.L. 
Published: July 2021

De raadsheer-commissaris in het enquêterecht
De raadsheer-commissaris houdt toezicht op de procesmatige kant van het onderzoek door middel van het geven van aanwijzingen aan de onderzoeker respectievelijk het geven van bevelen aan de rechtspersoon of belanghebbenden. Sinds de introductie in 2013 is de raadsheer-commissaris minstens twintig keer in actie gekomen in vijftien verschillende enquêtes.
Patient-Centered Care and People-Centered Health Systems in Sub-Saharan Africa: Why So Little of Something So Badly Needed?
Authors: De Man Jeroen , Mayega Roy William , Sarkar Nandini , Waweru Evelyn , Leys Mart , Van Olmen Josefien , Criel Bart 
Published: July 2021

Patient–centered care (PCC) is increasingly recognized as a key dimension of quality healthcare, but unfortunately remains poorly implemented in practice. This paper explores the current state of PCC in sub-Saharan Africa and potential barriers to its implementation, with a focus on public first line health services. We develop an analytical framework based on expert knowledge, field experience, and a conceptual literature review. Factors contributing to the (lack of) implementation of PCC are structured in three distinct but interacting layers. The first layer encompasses factors that influence and shape the performance of providers. The training of health workers is key in that respect. Training models remain dominated by a biomedical perspective, with little attention for psychosocial dimensions of the illness experience. The second layer of determinants relates to the structural and organizational features of the health system. The emphasis in many African health care systems on specific programmatic outputs, and the subsequent pressure this creates on health workers, jeopardize the delivery of PCC. The third layer is related to the broader socioeconomic environment in which health workers operate. Noteworthy is the gap between the “official” norms in the public sector and the actual behavior of providers. We then propose possible avenues for change for each of these three layers. We conclude by arguing the need for further fine-tuning of the framework outlined in this paper, investing in the contextual validation of measurement tools for PCC, and testing solutions in a participatory action research framework.
Measurement of Liability to Addiction: Dimensional Approaches
Authors: Vanyukov Michael , Cornelius Marie , De Genna Natacha , Reynolds Maureen , Kirillova Galina , Maher Brion , Kirisci Levent 
Published: July 2021

Background: Biomedical research and its applications, particularly in complex disorders, have historically been guided by the group-defined disease-oriented perspective rather than a person-centered health-oriented approach. This has been an obstacle to the development of prevention and treatment methods. There is thus a need to redirect studies to augment diagnostic systems with individualized phenotypic measurement. Objectives: The goal of this paper is to develop a pragmatic dimensional perspective on the complex traits underlying probabilities of disorder development. Method: Selective literature review of the foundation and methods for measuring liabilities to complex disorders and its aspects, and consultation on practical approaches. Results: The paper presents novel applications of the person-centered principle in psychiatric research, particularly addiction science, which can be used in any translation-oriented etiological health studies. These applications focus on the quantitative measurement of the individual phenotype along the full scale of the latent trait of liability and its understudied aspect, resistance to the disorder. Conclusions: The novel perspective and methodology we introduce facilitate a shift from the group-defined “disease” to the person-centered individual liability phenotype, and from the factors that lead to and determine risk for disease to the mechanisms that result in health and determine resistance to a disorder.
INTERNATIONAL PERSPECTIVES ON WELL-BEING AND BURNOUT WITHIN HEALTH SYSTEMS
Authors: Appleyard James 
Published: July 2021

Objectives: To reflect on the present international culture of professional burnout
in health care systems and the need for a radical new approach with an increased
understanding of a person- and people-centered attitudes in the promotion of
training in wellbeing and the prevention and management of burnout among
physicians and health care professionals
Methods: A literature search worldwide was undertaken for significant research
papers on professional education related to burnout with particular reference to
both medical staff resilience and health care system factors.
Findings: Burnout among doctors is a global phenomenon. The incidence of
burnout reported in a selection of studies among pediatric residents and staff are
25% in Argentina, 37% in the United Kingdom, and 70% in Saudi Arabia. In a
national survey in the United States where the overall rate was 59% burned out
residents reported significantly increased stress, poorer mental health, and
decreased empathy, mindfulness, resilience, self-compassion, and confidence in
providing compassionate care Three levels of change that should be the focus of
training in prevention, health promotion, and stress reduction awareness have been
recommended to reduce the risk of burnout: (1) modifying the organizational
structure and work processes; (2) improving the fit between the organization and
the individual doctor through professional development programs so that better
adaption to the work environment occurs; and (3) individual-level actions to reduce
stress and poor health symptoms through effective coping and promoting healthy
behavior.
Discussion: The history of burnout shows important links with increased work
complexity. Narrow training interventions such as debriefing after an adverse
clinical event have not been found effective. A more comprehensive personcentered
approach with a variety of measurable interventions has resulted in a
reduction of 50% in the pediatric faculty in one study. A person- and
people-centered cybernetic approach is needed with six standards are to establish
and sustain a healthy work environment (1) authentic leadership (2) meaningful
recognition, (3) skilled communication, (4) true collaboration, (5) effective
decision making, and (6) appropriate staffing.
Conclusion: With such high levels of burnout, health systems worldwide can be
viewed as failing their populations on a grand scale. Only an organizational
paradigm change to a person- and people cybernetic centered system that
incorporates complexity is adaptive and integrative will a health system be
effective in preventing and ameliorating the effects of burnout and reduce the
increasingly unaffordable misuse of human resources.
7TH INTERNATIONAL CONGRESS OF PERSON CENTERED MEDICINE
Authors: Mezzich Juan 
Published: July 2021

Congress Presidents: Yoshitake Yokokura, President of JMA and Jon Snaedal,
President of ICPCM
Organizing Committee: International College of Person Centered Medicine,
ICPCM: Jon Snaedal (President,), Juan E. Mezzich (Secretary General), Jim
Appleyard (Board Advisor), Michel Botbol (Board Member), Tesfamicael
Ghebrehiwet (Board Member), Helen Millar (Board Member), Ihsan Salloum
(Board Member), Werdie Van Staden (Board Member), and Japan Medical
Association.
Proposal of two new genera of the family Zosimeidae Seifried (Copepoda: Harpacticoida): Heterozosime gen. nov. and Acritozosime gen. nov.
Authors: Kim Jong Guk , Lee Jimin 
Published: July 2021

In the Pacific Ocean, the taxonomy of the family Zosimeidae Seifried, 2003 is poorly understood and to date only five species of the genus Zosime Boeck, 1873 are known. During oceanographic cruises exploring the species diversity of harpacticoids, two undescribed zosimeid copepods were sampled from shallow Korean waters and the deep northwestern Pacific. A detailed morphological examination has led us to propose two new genera, Heterozosime gen. nov. for the Korean zosimeid H. tenuis gen. et sp. nov. and Acritozosime gen. nov. for the deep-sea zosimeid A. spinesco gen. et sp. nov. Both new genera exhibit a distinctive feature in that the first thoracic leg has a two-segmented exopod, in contrast to the three-segmented exopod of this leg in all known zosimeid genera. Furthermore, Acritozosime gen. nov. can also be discriminated from other genera by the two-segmented endopod in second to fourth thoracic legs and the reduced setal armatures of the second exopodal segment of antenna, the first endopodal segment of first to third thoracic legs and the third exopodal segment in second to fourth thoracic legs. A comparison of the fundamental structures of appendages suggests that A. spinesco gen. et sp. nov. experienced a unique evolutionary history within the Zosimeidae.
A eficácia das decisões jurisdicionais liminares estrangeiras no ordenamento jurídico brasileiro
Authors: Posser Andrês Uliana , Conceição Lucas Gonçalves , Aragão Valdenir Cardoso 
Published: July 2021

O fenômeno globalizante cada vez mais intensificado e o complexo procedimento de nacionalização de sentenças estrangeiras, aliados à indiscutível importância das tutelas antecipadas para a satisfação eficaz dos ideais de justiça, trouxeram a necessidade de se problematizar a forma como as decisões liminares estrangeiras passam a ter eficácia em face do aparelho jurisdicional brasileiro, já que a fonte legal e a jurisprudencial caminham em sentidos contrários. A primeira mostra-se rígida na exigência do trânsito em julgado, enquanto a segunda, com um viés mais flexibilizado e justo, revela-se no sentido de possibilitar a eficácia das decisões meramente liminares. O presente trabalho visa, portanto, por meio de uma revisão bibliográfica, entender como essas decisões interlocutórias estrangeiras que concedem medidas antecipatórias passam a produzir efeitos dentro do ordenamento jurídico brasileiro.
Hegemonia e contestação: a aproximação de Caetano Veloso à teoria crítica coxiana
Authors: Bourscheid Junior Ivan 
Published: July 2021

Neste estudo se efetuará a análise de quatro canções de Caetano Veloso relativas ao período dos anos 1990 e 2000, evidenciando sua contribuição para a compreensão das relações internacionais deste período, com enfoque nas temáticas centrais apresentadas pelo artista nas canções. Elucidar-se-á a crítica de Caetano ao projeto hegemônico estadunidense, aportando seus desafios e limites que, quando confrontados definitivamente, resultaram na transformação do modo de atuação dos Estados Unidos, recorrendo aos meios coercitivos para a manutenção do Sistema Internacional. Portanto, ao realizar tais análises, intenta-se aproximar as contribuições de Caetano Veloso para a percepção dos fenômenos internacionais com os apontamentos da teoria crítica coxiana, compreendendo sua lógica hegemônica e fornecendo alternativas viáveis para a solução das problemáticas humanas centrais que permeiam tal contexto.
Effectiveness of Farmer Field School and Conventional Extension Trainings on Knowledge Gain among Farm Women
Authors: Krishnan J. , Ranganathan T. T. , Ravichamy P. , Sivabalan K. C. 
Published: July 2021

The world extension forum over three-four decades emphasized the people centric bottom up approach in extension work.
In mid 1970s world bank had introduced Training and Visit (T&V) system of extension in 70 countries including India. This solely emphasized the dissemination of Green Revolution technologies to farmers, mainly in Asian and African countries with top down extension approach. Subsequently, FFS emerged in the rice paddy fields of the Philippines and Indonesia in the late 1980s where, Food and Agriculture Organization (FAO) had heavily involved from its incubation, development and spread to Asian, African countries and other parts of world in 1990s with the emphasis on bottom up approach and participatory extension services. This demanded a paradigm shift in extension purview and its methodology to factor upon farming fraternity participation in all possible ways. Despite that the technology transfer process remains unchanged and unrefined till now. The best features of extension methodologies are identified by making literature review pertaining to Farmer Field School (FFS) and Training and Visit (T&V) method of extension trainings. Both Farmer Field School (FFS) and conventional extension training methodologies were used to train women groundnut growers in Pennagaram villages, Dharmapuri, India and the change in knowledge level and the effectiveness of methodologies were studied. In context, 29 important crop production practices in groundnut cultivation were identified and surveyed with 300 participants of which, 50% of participants ( n=150) exposed to FFS way of training and 50% of participants (n=150) exposed to T&V way of training. Most (90-95%) of the survey respondents found that the FFS way of training as better effective than T&V way of training. Similarly, the knowledge level of 80 to 85% of participants who participated FFS way of training found to be more than the participants who attended T&V way of training.
Characterization of Chemical Composition of Bryophyllum pinnatum Leaf Ethyl Acetate Fraction
Authors: Asiwe E. S. , Igwe C. U. , Onwuliri V. A. , Iheanacho K. M. E. , Iheanacho J. N. 
Published: July 2021

Aims: To characterize the chemical composition of Bryophyllum pinnatum leaf ethyl acetate fraction.
Methodology: Quantitative phytochemical composition was assessed using gas chromatography fitted with flame ionization detector (GC-FID), while chemical characterization was via gas chromatography-mass spectrophotometry (GC-MS) analysis. The mass spectra peaks were matched with those found in the National Institute of Standard and Technology (NIST) spectral database.
Results: Results revealed a rich presence of proanthocyanin, rutin, quinine, flavan-3-ol, anthocyanin, lunamarin, sapogenin, phenol, flavonones, steroids, epicatechin, kaempferol, phytate, oxalate, resveratol, catechin, flavones, tannin, ribalinidine, naringin, and spartein in varying proportion in B. pinnatum leaves ethylacetate fractions. GC-MS analysis of the fractions revealed the presence of at least 50 constituents. The major constituents were Hexadecanoic acid, methyl ester (24.88%), 10,13-Octadecadienoic acid, methyl ester (29.69%), Tetracosanoic acid, methyl ester (7.84%), Methyl stearate (6.97%), cis-Methyl 11-eicosenoate (6.26%), Methyl 18-methylnonadecanoate (4.99%), Docosanoic acid, methyl ester (3.71%) and 4,7-Methano-1H-indene, octahydro- (2.43%).
Conclusion: This rich array of chemical compounds presents B. pinnatum leaves as an important source of potential lead compounds with biological and pharmacological benefits and hence a potential candidate for drug discovery.