bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effectiveness of Using Breastfeeding Program for Father via Facebook to knowledge, Attitude, Behavior of Supporting of 6-Month Exclusive Breastfeeding in Low-Income Country
Authors: thepha Thiwawan , Theeranut Ampornpan 
Published: September 2021

Abstract
Background: The six-month exclusive breastfeeding rate in the Northeast region of Thailand has recently significantly decreased in contrast to all other regions in Thailand. Facebook is world widely use to increase that knowledge, attitude and behaviour to support breastfeeding. Therefore, the aim of this study is to test the effectiveness of using 6-month breastfeeding program for father via Facebook to knowledge, attitude, behavior of supporting of breastfeeding in low-income country.Method: A quasi-experimental design was used. The study was carried out from September 2020 – August 2021. The data of experimental group and control group were conducted in two tertiary hospital in Khonkaen province, Northeast Thailand. The participants were husbands of postpartum mothers who were admitted to the Obstetrics ward , Khonkaen Hospital, 2A and 2B ward, Srinagarin Hospital. The demographic data were analyzed by distribution of frequency, mean, percentage and standard deviation. The t-test were used to analyse the mean score of knowledge, attitude and behaviour of father by SPSS version 27. Results: 72 father were included. The different mean score of knowledge, attitude, behaviors of father to support the EBF among baseline and 6-month were shown. In intervention group, the different mean score of knowledge among baseline and 6-month was significant at P-value 0.01. The mean of knowledge at 6 months (mean=19.78, SD=5.50) was higher than the mean of knowledge baseline (mean=16.42, SD=4.22). Similarly, the different mean score of attitudes among baseline and 6-month was significant at P-value 0.14. The mean of attitude at 6-month (mean=108.03, SD=19.89) was higher than the mean of behaviour at baseline (mean=101.81, SD=17.99). In addition, the different score of behaviour among baseline (mean=65.86, SD=7.01) and 6-month (mean=68.58, SD=10.42) was significant at P-value=0.16. The mean score of behavior at baseline is lower than the mean of behaviour at 6 months. In control group, these is only the different mean of behavior baseline and 6-month was significant at P-value=0.00.Conclusions: This confirm that FB is good platform to transfer the breastfeeding knowledge to father in low income country. In the future, this program can be improved and test in other country that has the same condition.
Complications of Ovarian Cancer Surgery in Dr. Cipto Mangunkusumo National Referral Hospital, Jakarta
Authors: Purwoto Gatot , Dalimunthe Boeyoeng Ego , Kekalih Aria , Aditianingsih Dita , Mazni Yarman , Wahyudi Irfan , Julianti Kelli 
Published: September 2021

Abstract
Background: Ovarian cancer remains as one of the deadliest gynecologic problems globally. Often appears in advanced state, its surgery proves to be a challenge for clinicians. This study aim to present complications surrounding ovarian cancer surgery.Methods: This study was a cross-sectional study to analyze reports of intraoperative and postoperative complications in ovarian cancer patients undergoing laparotomy in Dr. Cipto Mangunkusumo National General Hospital, Jakarta from January 2018 to December 2019. Ovarian cancer patients undergoing laparotomy surgery were included in the study. Patients with a history of other cancers or having incomplete data were excluded from the study. Intraoperative complications included intestinal, ureter, bladder injury, and postoperative complications included paralytic ileus, surgical wound infection and sepsis were documented.Results: A total of 78 subjects were included in the study. The total proportion of complications was 19.2%. The most prevalent intraoperative complications were intestinal injury (12.8%), bladder injury (2.6%), and ureter injury (1.3%). Most prevalent postoperative complications reported were surgical wound infection (5.2%), sepsis (3.9%), while none of the patients had paralytic ileus.Conclusion: The proportion of intraoperative and postoperative complications in ovarian cancer surgery was still at alarming level (19.2%). Further steps are needed to ameliorate the rate of complications surrounding ovarian cancer surgery.
WITHDRAWN: Rider Weed Deep Residual Network-Based Incremental Model for Text Classification Using Multidimensional Features and MapReduce Framework
Authors: Abdalla Hemn Barzan 
Published: September 2021

Abstract
The increasing demand for information and rapid growth of big data has dramatically increased textual data. The amount of different kinds of data has led to the overloading of information. For obtaining useful text information, the classification of texts is considered an imperative task. This paper develops a technique for text classification in big data using the MapReduce model. The goal is to design a hybrid optimization algorithm for classifying the text. Here, the pre-processing is done with the steaming process and stop word removal. In addition, the Extraction of imperative features is performed wherein SentiWordNet features, contextual features, and thematic features are generated. Furthermore, the selection of optimal features is performed using Tanimoto similarity. The Tanimoto similarity method estimates the similarity between the features and selects the relevant features with higher feature selection accuracy. After that, a deep residual network is utilized for dynamic text classification. The Adam algorithm trains the deep residual network. In addition, the dynamic learning is performed with the proposed Rider invasive weed optimization (RIWO)-based deep residual network along with fuzzy theory. The proposed RIWO algorithm combines Invasive weed optimization (IWO) and the Rider optimization algorithm (ROA). The method mentioned above is solved under the MapReduce framework. The proposed RIWO-based deep residual network outperformed other techniques with the highest True positive rate (TPR) of 85%, True negative rate (TNR) of 94%, and accuracy of 88.7%.
A skeletal Class III malocclusion with agenesis and canine-bicuspid transposition: a non-surgical approach
Authors: Bellot-Arcís Carlos , García-Sanz Veronica , Paredes-Gallardo Vanessa 
Published: September 2021

Abstract

Background
The present case report describes the orthodontic management of a patient who presented with a skeletal Class III malocclusion combined with other dental anomalies. The malocclusion was complicated by agenic maxillary lateral incisors and a lower right second premolar, in company with the transposition of the maxillary canines and premolars.

Methods
Dentoalveolar compensation of the anteroposterior jaw relationship was performed. The upper deciduous lateral incisors were extracted and the spaces closed, so that the first premolars replaced the missing lateral incisors while the canine transposition was maintained

Results
Satisfactory results were obtained which provided an improvement in function and occlusal stability, as well as smile and profile aesthetics.

Conclusion
This case demonstrates the importance of an accurate diagnosis when many treatment options are available and clearly addressed.
The effect of the lateral cephalometric radiograph on orthodontists’ diagnosis and treatment decisions: a double-blind, randomised controlled trial
Authors: Currell Scott Derek , Roberts Sophie May , Abdalla Yousef , Esterman Adrian 
Published: September 2021

Abstract

Aims
To evaluate the influence of the lateral cephalometric radiograph on orthodontists’ diagnosis and treatment planning decisions.

Methods
Five patients with full pre-treatment records were selected to represent a spectrum of malocclusions. The records were provided in a web-based questionnaire emailed to 510 Australian registered orthodontists. Participants were asked to formulate a diagnosis and treatment plan for a randomised patient case. The control group received a lateral cephalometric radiograph whilst the intervention group did not. The two groups’ diagnostic accuracy was determined by a comparison with the formative diagnoses determined by five senior academic orthodontists. Their diagnosis and treatment planning decisions were also compared.

Results
A comparison of the orthodontists’ diagnoses revealed that the lateral cephalometric radiograph did not lead to an increase in the assessment accuracy of dental (p = 0.797) and skeletal (p = 0.273) relationships. Further analysis using logistic regression showed that the orthodontists’ years of experience did not influence the accuracy of skeletal diagnosis (p = 0.177). A comparison between the orthodontists’ dental (p = 0.689) and skeletal (p = 0.321) determinations did not significantly differ between the two groups. An assessment of the vertical growth pattern (p = 0.656) was also unaffected by the omission of the lateral cephalometric radiograph. When the two groups considered treatment planning options, there were no statistically significant differences related to the treatment options of growth modification (p = 0.720), orthognathic surgery (p = 0.101), and/or an extraction decision (p = 0.840).

Conclusion
Lateral cephalometric radiographs did not significantly influence orthodontists’ diagnosis. There was also little evidence to demonstrate the radiograph’s efficacy in treatment planning cases with no skeletal discrepancy or no significant labiolingual incisor movement planned.
Upper-molar intrusion using anterior palatal anchorage and the ‘Mini-Mousetrap’ appliance
Authors: Wilmes Benedict , Niegel Thomas , Drescher Dieter 
Published: September 2021

AbstractThe intrusion of over-erupted upper molars is an orthodontic problem of major difficulty. When conventional appliances are used, the extrusion of adjacent teeth is likely. However, in recent years, temporary anchorage devices have been used to avoid unwanted side effects. For this purpose, mini-implants have primarily been inserted in the alveolar process. However, due to many disadvantages associated with mini-implant placement between the roots of the upper molars, it is now preferred to insert miniimplants in the anterior palate, which ensures a low risk of failure or mini-implant fracture.The ‘Mini-Mousetrap’ appliance (without a TPA) was designed as a less bulky alternative to the ‘Mousetrap’ (with a TPA), and is comprised of two mini-implants in the anterior palate and attached lever arms for molar intrusion. If a TPA is not used, molar movement must be monitored and the direction of the force adjusted to avoid unwanted molar tipping.
Application of Pont’s index to a Pakistani population: a digital stereomicroscopic study
Authors: Shahid Fazal , Alam Mohammad Khursheed , Khamis Mohd Fadhli , Townsend Grant Clement 
Published: September 2021

Abstract

Objective
To investigate the applicability of Pont’s index for predicting maxillary and mandibular dental arch widths in a Pakistani population.

Materials and methods
A Hirox digital stereomicroscope (SM) (HIROX KH7700 Japan) was used to construct digital models of fabricated plaster casts. Gender differences in the measured totals of the incisor widths, arch widths and expansion indices were evaluated. Pont’s correlations were computed between measured and predicted arch widths. An analysis of variance (ANOVA) was applied to determine the differences between arch length and arch perimeter groups.

Results
Males had significantly larger mean values for the sums of the incisors, arch widths and expansion indices compared with females (p ≤ 0.05). There were significant differences observed between the large and small, average and small and the average and large arch length groups (p ≤ 0.05) in the maxilla, while a significant difference was observed only between the large and small arch length groups in the mandibular arch. Pont’s index predictions were consistently less than the actual interpremolar and intermolar arch widths for both genders. The dissimilarity in the predictions for interpremolar width averaged -4.33 mm for males and -4.21 mm for females while the intermolar width averages were -4.93 mm for males and -4.92 mm for females.

Conclusion
The results indicated that Pont’s index should not be applied to the Pakistani population. Maxillary and mandibular arch length groups and arch perimeters should be carefully investigated before applying any prediction formulae.
The Hawlix: a simple and aesthetic prosthetic-orthodontic retainer
Authors: Doğramacı Esma J. , Jones Vaughan S. , Jones Allan G. 
Published: September 2021

Abstract
This report introduces the Hawlix, a hybrid thermoformed and cold-cured retainer. It was developed to overcome the limitations that modified Hawley retainers possess when used in patients with bounded saddles, attributable to dental trauma or hypodontia. The Hawlix can be used as an intermediate retainer while a patient is waiting to receive restorative treatment. Some of the advantages of the Hawlix over the modified Hawley retainer include: superior aesthetics, cost-effectiveness, ease of manufacture, adequate resistance to fracture, preservation of a residual ridge, and precise space maintenance.
Small Colony Variants – The Cause Of Chronic Infections
Authors: Nowicka Joanna , Piątkowska Elżbieta 
Published: September 2021

Abstract
Some microorganisms are characterised by the ability to create specific morphological varieties called Small Colony Variants (SCVs). This characteristic was noted, among others, in Gram-positive cocci, mainly staphylococci, but also in Gram-negative bacilli. The properties of Small Colony Variants that differentiate them from wild-type colonies (mainly their small size) facilitate their intracellular survival (e.g. in epithelial or endothelial cells) as a result of which they can escape host immune response. In this way, SCV forms avoid the effects of complement components or antibodies. They are also characterised by resistance to antibiotics, mainly aminoglycoside or combination drugs, such as trimethoprim-sulfamethoxazole. The above features, which are important from a clinical point of view, namely small size and antibiotic resistance, make SCV one of the main causes of chronic, latent and recurrent infections which are difficult not only to diagnose, but also to treat. According to the literature, SCV of various microorganisms can be isolated from systemic infections of various organs and therefore from different clinical materials (e.g. blood, bones, soft tissues). SCV forms of Staphylococcus aureus are often isolated from patients with cystic fibrosis or osteomyelitis. The paper presents the characteristics and clinical relevance of this unique morphological form of bacteria.
Is There A Relationship Between The Intestinal Microbiota And Diabetes?
Authors: Wujkowska Alicja , Sińska Beata 
Published: September 2021

Abstract
Due to the total number of microorganisms and multitude of roles they play in the human body, intestinal bacteria are increasingly called the “microbial organ”. Proper composition of the gastrointestinal microbiome is necessary to maintain human health. According to the latest studies, the imbalance in the composition of intestinal microorganisms, called dysbiosis, can result in development of numerous diseases, including metabolic disorders e.g. diabetes. The incidence of this disease is constantly increasing. The pathogenesis of diabetes is complicated and not yet fully understood. However, it is known that many factors influence its development. Intestinal microbiota is increasingly mentioned among them. Based on a literature review related to the subject, it can be concluded that dysbiosis, intestinal barrier damage and endotoxemia adversely affect metabolic parameters.
Expression Analysis of Lanosterol Synthase Gene in Dynamic Accumulation of Triterpenoids in Sanghuangporus baumii
Authors: Wang Xu Tong , Sun Ting Ting , Sun Jian , Wang Shixin , Zou Li 
Published: September 2021

Background:
Sanghuangporus baumii is a traditional Chinese medicine with anti- cancer,
anti-tumor, and anti-inflammatory effects. Triterpenoids are one of the main medicinal ingredients
found in S. baumii. However, the dynamic changes of triterpenoids content and its molecular
regulation mechanism are still unclear.

Objective:
Some studies have shown that Lanosterol synthase (LS) is a key enzyme involved in the
mevalonate pathway (MVA pathway) to produce lanosterol, which is a precursor for synthesizing
S. baumii triterpenoids. Therefore, the study of LS gene and expression characteristics can provide
clues for the further study of triterpenoids synthesis.

Methods:
The PCR, RACE PCR, RT-PCR, homologous recombination and prokaryotic expression
technology were used to research the gene characteristic and dynamic changes of LS transcription
level.

Results:
The S. baumii LS sequence included a 5’-untranslated region (129 bp), a 3’-untranslated region (87 bp), and an open reading frame (2,229 bp) encoding 734 amino acids. The S. baumii LS protein was expressed in E. coli BL21 (DE3). The transcription start site of the S. baumii LS promoter sequence ranged from 1 740 bp to 1790 bp. The LS promoter contained 12 CAAT-boxes, 5 ABREs, 6 G-Boxes, 6 CGTCA-motifs, and so on. The LS transcription levels were the highest on day 11 in mycelia (1.6-fold), and the triterpenoids content also gradually increased. The transcription levels began to decrease on day 13, but the triterpenoids content still increased.

Results:
The S. baumii LS sequence included a 5’-untranslated region (129 bp), a 3’-untranslated region
(87 bp), and an open reading frame (2,229 bp) encoding 734 amino acids. The S. baumii LS
protein was expressed in E. coli BL21 (DE3). The transcription start site of the S. baumii LS promoter
sequence ranged from 1 740 bp to 1790 bp. The LS promoter contained 12 CAAT-boxes, 5
ABREs, 6 G-Boxes, 6 CGTCA-motifs, and so on. The LS transcription levels were the highest on
day 11 in mycelia (1.6-fold), and the triterpenoids content also gradually increased. The transcription
levels began to decrease on day 13, but the triterpenoids content still increased.

Conclusion:
The S. baumii LS was cloned and characterized to help to understand the mechanism
of triterpenoids synthesis. In addition, we studied the relationship between LS transcription level
and triterpenoid dynamic accumulation, and we found that they had a certain correlation.
Neutrophil/Lymphocyte, Platelet/Lymphocyte, and Monocyte/Lymphocyte Ratios in Mood Disorders
Authors: Marazziti Donatella , Torrigiani Samuele , Carbone Manuel G. , Mucci Federico , Flamini Walter , Ivaldi Tea , Dell'Osso Liliana 
Published: September 2021

:
Major depressive disorder (MDD) and bipolar disorders (BDs), the most severe
types of mood disorders (MDs), are considered as among the most disabling illnesses
worldwide. Several studies suggested that inflammatory neuroinflammation might be involved
in the pathophysiology of MDs while reporting increasing data on the relationships
between these processes and classical neurotransmitters, hypothalamus-pituitaryadrenal
axis (HPA), and neurotrophic factors. The assessment of neutrophil/lymphocyte
ratio (NLR), platelet/lymphocyte ratio (PLR), and monocyte/lymphocyte ratio (MLR) in
peripheral blood represents a simple method to evaluate the inflammatory status. The aim
of the present paper was to review the literature on the possible relationships between
NLR, PLR, and MLR in MDs and to comment on their possible wider use in clinical research.
Thirty-five studies were included in the present review. The majority of them had
higher values of these parameters, particularly NLR values in patients with MDs when
compared to healthy subjects. The increase would appear more robust in patients with BD
during a manic episode, thus indicating that it could be considered as both state and trait
markers. In addition, increased NLR and PLR levels seem to represent prognostic elements
for the early discovery of post-stroke depression. The findings of the present review
would indicate the need to carry out further studies in this field. In particular, NLR,
PLR, and MLR seem to be promising tools to detect economically and easily the activation
of the inflammatory system and to perhaps evaluate the etiology and course of MDs.
Again, they could suggest some information to better understand the relationship between
inflammatory and cardiovascular disease and MDs, and thus, to provide clinical implications
in terms of management and treatment.
Headache in Multiple Sclerosis - Pharmacological Aspects
Authors: Gebhardt Marcel , Kropp Peter , Hoffmann Frank , Zettl Uwe K. 
Published: September 2021

:
For decades, the headache was not considered a typical symptom of multiple sclerosis (MS) and was
construed as a “red flag” for important differential diagnoses such as cerebral vasculitis. Meanwhile, several
studies have demonstrated an increased prevalence of headaches in MS compared to the general population.
This is due to the heterogeneity of headache genesis with frequent occurrence of both primary and secondary
headaches in MS. On the one hand, MS and migraine are often comorbid. On the other hand, secondary headaches
frequently occur, especially in the course of MS relapses. These are often migraine-like headaches
caused by inflammation, which can improve as a result of MS-specific therapy. Headaches are particularly common
in the early stages of chronic inflammatory CNS disease, where inflammatory activity is the greatest. In addition,
headaches can also occur as a side effect of disease-modifying drugs (DMDs). Headache can occur with
most DMDs and is most frequently described with interferon-beta therapy. The aim of this work is to present
the prevalence of headaches and describe the heterogeneity of possible causes of headaches in MS. In addition,
important therapeutic aspects in the treatment of MS patients, in general, will be presented as well as different
approaches to the treatment of headaches in MS depending on the etiological classification.
Decreased Plasma Level of Lipoprotein Lipase Predicted Verbal Disfluency in Chinese Type 2 Diabetes Mellitus Patients with Early Cognitive Deficits
Authors: An Ke , Guo Peng , Zhang Haoqiang , Zhu Wenwen , Cao Wuyou , Shi Jijing , Wang Shaohua 
Published: September 2021

Background :
Lipoprotein Lipase (LPL) is the rate-limiting enzyme catalyzing the hydrolysis
of triglycerides and contributes to the amyloid-β formation, which shows promise as a
pathological factor of cognitive decline in Type 2 Diabetes Mellitus (T2DM). This study aimed to
investigate the pathogenetic roles of LPL and rs328 polymorphism in Mild Cognitive Impairment
(MCI) in patients with T2DM.

Methods:
Chinese patients with T2DM were recruited and divided into two groups based on the
Montreal Cognitive Assessment score. Demographic data were collected, LPL was measured and
neuropsychological test results were examined.

Results:
Seventy-nine patients with diabetes and MCI had significantly decreased plasma LPL levels
(p = 0.007) when compared with health-cognition controls (n = 91). Correlation analysis revealed
that LPL was positively correlated with clock drawing test (r = 0.158, p = 0.043) and logical
memory test (r = 0.162, p = 0.037), while lipoprotein a (r = -0.214, p = 0.006) was inversely associated
with LPL. Logistic regression analysis further demonstrated that LPL concentration was an independent
factor for diabetic MCI (p = 0.036). No significant differences were observed in the distributions
of rs328 variants between patients with MCI and the controls. Moreover, no remarkable
association was found among plasma LPL levels, cognitive performances, and lipid levels between
the genotypic subgroups. The trail making test A was increased in the GC group when compared
with the CC genotype in the control group.

Conclusion:
Decreased plasma level of LPL could probably predict early cognitive deficits, especially
verbal disfluency.