bluuebunny/crossref_metadata_2025_split huggingface dataset:
More on testing granular filtering materials in accordance with GOST R 51641-2000
Authors: Беляк А.А. , Смирнов А.Д. 
Published: July 2021

Возможность ошибок в определении свойств фильтрующих зернистых материалов заложена в самом ГОСТ Р 51641-2000 «Материалы фильтрующие зернистые. Общие технические условия» из-за неточностей в методиках испытаний. На основании опыта НИИ ВОДГЕО в выполнении испытаний различных фильтрующих материалов даются предложения по уточнению и корректировке этих методик, позволяющие получить достоверные и воиспроизводимые результаты для оценки физико-химических свойств материалов. Для получения реальных воспроизводимых результатов по основным методикам ГОСТ Р 51641-2000 их необходимо корректировать в части пробоподготовки, определения показателей химической стойкости и механической прочности фильтрующего материала в соответствии с предложенными рекомендациями. Данные предложения, основанные на практическом опыте испытаний различных фильтрующих материалов (песков, цеолитов, активных углей и др.), позволяют получить достоверные воспроизводимые результаты, которые не противоречат методикам ГОСТ Р 51641-2000.
Possible errors while determining the properties of filtering granular materials are laid down in GOST R 51641-2000 «Granular filtering materials. General specifications» because of theinaccuracies in the test methods. Based on the experience of NII VODGEO in performing tests of various filtering materials, suggestions on improving and adjusting these methods are presented that provide for obtaining reliable and reproducible results for the estimation of the physical and chemical properties of materials. To obtain actual reproducible results according to the main methods defined in GOST R 51641-2000, correcting the processes of sample preparation, determination of chemical resistance indicators and mechanical strength of the filter material is needed in accordance with the proposed recommendations. These proposals, based on the work experience in testing various filter materials (sand, zeolite, activated carbon, etc.), provide for obtaining reliable reproducible results that do not contradict the methods of GOST R 51641-2000.
AKTIVITAS ANTIOKSIDATIF DAN ANTI-GLIKASI EKSTRAK FENOLIK BEBAS DAN FENOLIK TERIKAT DARI TONGKOL JAGUNG
Authors: Suryanto Edi , Taroreh Mercy 
Published: July 2021

Penelitian ini bertujuan untuk menentukan aktivitas antioksidan dan anti glikasi ekstraks fenolik bebas dan ekstrak fenolik terikat dari tongkol jagung. Tongkol jagung diekstraksi secara sekuensial berbantu ultrasonikasi dengan pelarut etanol dan aseton selama 60 menit yang untuk mendapatkan ekstrak fenolik bebas. Residu dari ekstraksi fenolik bebas dihidrolisis dengan NaOH 2 M dan dinetralkan serta diekstraksi dengan etil asetat untuk mendapatkan ekstrak fenolik terikat. Ketiga ekstrak tersebut dilakukan analisis kandungan total fenolik dan pengujian aktivitas antioksidan dan anti glikasi. Kandungan total fenolik ekstrak ekstrak fenolik terikat (EFT), ekstrak fenolik bebas aseton (EFBA) dan ekstrak fenolik bebas etanol (EFBE) berturut-turut adalah 288,39; 100,32 dan 92,95 μg/mL yang dinyatakan sebagai ekuivalen asam galat. Ekstrak EFT menunjukkan aktivitas penangkalan radikal bebas DPPH dan total antioksidan lebih tinggi daripada ekstrak EFBA dan ekstrak EFBE. Sejalan dengan itu, aktivitas anti glikasi dari EFT, EFBA dan EFBE berturut-turut adalah 61,93; 64,42 dan 66,31%. Hasil penelitian ini menyimpulkan bahwa ekstrak EFT dari tongkol jagung mengandung senyawa yang memilki sifat antioksidan dan berpotensi sebagai anti glikasi. ABSTRACTThis objective of this research was to determine the antioxidant activity and inhibition of AGEs formation of free phenolic and bound phenolic extract from corn cobs. Corn cobs were extracted sequentially assisted by ultrasonication with ethanol and acetone solvents for 60 minutes to obtain free phenolic extract. The residue from free phenolic extraction was hydrolyzed with 2 M NaOH and neutralized and extracted with ethyl acetate to obtain bound phenolic extract. The three extracts were analyzed for total phenolic content and evaluated for antioxidant activity and inhibitory activity of AGEs formation. The total phenolic content of bound phenolic extract (EFT), acetone-free phenolic extract (EFBA) and ethanol-free phenolic extract (EFBE) were 288,39; 100,32 and 92,95 μg/mL expressed as gallic acid equivalents, respectively. EFT extract showed higher DPPH free radical scavenging activity and total antioxidants more than EFBA extract and EFBE extract. Anti-glication of EFT, EFBA and EFBE were 61,93; 64,42 dan 66,31%, respectively. These result concluded that the EFT extract from corn cobs contains compounds having antioxidant properties and potential as anti-glication.
KARAKTERISASI DAN AKTIVITAS ANTIOKSIDAN SERAT PANGAN DARI TEPUNG KULIT LEMON CUI (Citrus microcarpa)
Authors: Dika Oki Oktaviani , Suryanto Edi , Momuat Lidya 
Published: July 2021

Tujuan dari penelitian ini untuk mengekstraksi dan mengkarakterisasi antioksidan serat pangan dari kulit lemon cui (Citrus microcarpa) dengan perbedaan pelarut menggunakan gelombang ultrasonik. Hasil penelitian menunjukkan bahwa tepung kulit lemon cui yang diekstraksi dengan perbedaan pelarut tidak mengalami perubahan mendasar pada komponen utama ditunjukkan pada hasil spectra Fourier Transfrom Infra Red (FT-IR). Karakterisasi secara kimia menunjukkan TPKLC memiliki kandungan air (8,49%), abu (4,44%), lemak (0,8%), protein (12,45%), dan karbohidrat (73,99%). AKLC mengandung air (1,71%), abu (4,41%), lemak (0,56%), protein (10,56%), karbohidrat (82,76%). EKLC mengandung air (7,88%), abu (6,18%), lemak (1,04%), protein (7,68%), karbohidrat (77,22%). Hasil pengujian aktivitas antioksidan menunjukkan bahwa ekstrak fenolik EKLC (96,48%) tertinggi diikuti oleh ekstrak fenolik AKLC (95,45%), dan ekstrak fenolik TPKLC (94,29%).Hasil penelitian ini menunjukkan bahwa dengan pelarut etanol dapat meningkatkan aktivitas antioksidan dibanding dengan pelarut aquades.ABSTRACTObjective of this study to extract and characterize antioxidant dietary fiber from lemon peel cui (Citrusmicrocarpa)with different solvents using wave ultrasonic. The results showed that the lemon cui peel powder extracted with different solvents did not experience a fundamental change in the main component as shown in the results of the Fourier Transfrom Infra Red (FT-IR) spectra. Chemical characterization showed that TPKLC contained water (8.49%), ash (4.44%), fat (0.8%), protein (12.45%), and carbohydrates (73.99%). AKLC contains water (1.71%), ash (4.41%), fat (0.56%), protein (10.56%), carbohydrates (82.76%). EKLC contains water (7.88%), ash (6.18%), fat (1.04%), protein (7.68%), carbohydrates (77.22%). The results of the antioxidant activity test showed that the highest EKLC phenolic extract (96.48%) was followed by AKLC phenolic extract (95.45%), and TPKLC phenolic extract (94.29%). The results of this study indicate that ethanol solvent can increase antioxidant activity compared to distilled water solvent.
The Role of Vitamin D Metabolite Deficiency in the Development of Structural and Functional Disorders in Coxarthrosis
Authors: Kalashnikov O.V. , Gayko G.V. , Burianov O.A. , Tymochuk V.V. , Poluliakh D.M. 
Published: July 2021

Summary. At present, there is a need to systematize the data of our own comprehensive research and literature in order to determine the role of active metabolites of vitamin D in the formation of structural and functional disorders (SFD) in osteoarthritis of the hip.
Objective: on the basis of our own complex researches and data of literature, to determine the role of the insufficiency of vitamin D metabolites in the development of SFD in coxarthrosis.
Materials and Methods. The basis for determining the role of active metabolites of vitamin D in the development of SFN in coxarthrosis was our own comprehensive studies of 506 patients with osteoarthritis of the hip and data from the literature.
Results. On the basis of the theory of functional systems, a conceptual model for the development of SFD in coxarthrosis has been developed. The leading factor in the development of SFD in the rapid progression of idiopathic and dysplastic osteoarthritis of the hip is the lack of active metabolites of vitamin D. The presence of undifferentiated connective tissue dysplasia in turn causes a decrease in the absorption of provitamin D in the stomach and intestines. With a slow progression of idiopathic coxarthrosis, the leading factor in the development of these disorders is the excessive load on the hip joint. Factors of violation of biomechanical conditions and injury of the hip joint are factors of the progression of coxarthrosis of dysplastic and post-traumatic genesis. Pathogenic factors lead to functional and structural changes in systems of different levels and their elements with the development of inverted processes in the structures of the hip joint.
Conclusions. Insufficiency of vitamin D metabolites on the background of undifferentiated connective tissue dysplasia leads to biochemical changes in articular cartilage and serum, affects both osteo- and chondrogenesis, leads to reduced immune status of patients and the development of clinical manifestations of rapid progression of idiopathic and dysplastic coxarthrosis. With a slow progression of idiopathic coxarthrosis, the main factor leading to the development of the above mentioned disorders is the excessive load on the hip joint. Factors of violation of biomechanical conditions and injury of the hip joint determine the development of SFD in coxarthrosis of dysplastic and post-traumatic genesis.
STAKEHOLDER PRESSURE AND THE QUALITY OF SUSTAINABILITY REPORT: EVIDENCE FROM INDONESIA
Authors: Lulu Claudia Leonirda 
Published: July 2021

This study aims to determine the effect of environmental pressure, consumer pressure, shareholder pressure, employee pressure, government pressure and creditor pressure on the quality of sustainability reports. The control variables of this study are profitability and company size. The sampling technique used is a purposive sampling method with the number of samples obtained as many as 69 non-financial sector companies listed in Indonesia Stock Exchange for the period of 2016-2018. A multiple linear regression method was used. The results of this study indicate that environmental pressure and consumer pressure have a positive effect on the quality of sustainability reports, while shareholder pressure, employee pressure, government pressure and creditor pressure do not affect the quality of sustainability reports. Profitability and company size as control variables in this study do not affect the quality of sustainability reports.
Keywords: stakeholder pressure, profitability, company size, quality of sustainability reports
ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI MOTIVASI MELAKUKAN PEMERIKSAAN PAP SMEAR PADA WANITA USIA SUBUR
Authors: Aminingsih Sri , Yulianti Tunjung Sri 
Published: July 2021

Background. One cause of death of women in Indonesia is cancer, one of which is cervical cancer. According to the 2013 Riskesdas data the incidence of cancer in Central Java was 2.1% with 1.2% being cervical cancer. Cervical cancer swallows many female victims in Indonesia, although it should be prevented by making efforts to prevent and detect early, one of them by carrying out a pap smear examination.
The Aim of the Study. Knowing the factors that affecting motivation conducting pap smear examination in woman of childbearing age.
Subject and Method. The research was analytic correlation design. The population in this study were women of childbearing age in the village of Wiragunan in September 2019 to March 2020 totaling 60 respondents. The sampling technique used is saturation sampling technique. The results of the study were analyzed using the Chi-Square Correlation Test.
Result. Respondents with high knowledge were 44 (73.33%), who had low knowledge of 16 respondents (26.67%). High family support there are 43 respondents (71.67%), low family support 17 respondents (28.33%). While respondents with high motivation 42 (70%) and low motivation 18 (30%). The results of the Chi Square analysis of the level of knowledge (p = 0.001), family support (p = 0.001) on the motivation to do the pap smear.
Conclusion. There is a relationship of knowledge about cervical cancer with the motivation to conduct pap smears in women of childbearing age. And there is a relationship of family support with the motivation to do a pap smear test on women of childbearing age.

Keywords : cervical cancer, family support, knowledge, motivation, pap smear test

Korespondensi: Sri Aminingsih. STIKES PANTI KOSALA SURAKARTA. Jalan Raya Solo - Baki Km. 4 Gedangan, Grogol, Sukoharjo, Jawa Tengah.
Email: s.aminingsih@yahoo.co.id.
EFEKTIVITAS SWEDISH MASSAGE TERHADAP KUALITAS TIDUR DAN TINGKAT INSOMNIA LANSIA
Authors: Rasam Rianayanti Asmira , Utami Ressa Andriyani 
Published: July 2021

Background. Insomnia is a complaint that often occurs in the elderly, if not resolved it can reduce the quality of life of the elderly. Proper handling can improve the quality of life of the elderly.
The Aim of The Study. This study aims to determine the effectiveness of Swedish massage on sleep quality and the level of insomnia in the elderly.
Subjects and Methods. The research design used quasi experiment non equivalent control group pretest-post test. The number of samples in this study were 62 people who were taken randomly, divided into an intervention group of 37 peoples who were given swedish massage therapy for 7 days and a control group of 25 peoples who were given worship therapy 2x a week, before and after the intervention vital signs were measured. Research analysis using binary logistic and t test difference.
Results. The results of binary logistic analysis and multiple linear regression showed a significant effect between swedish massage therapy on sleep quality on day 7 and the level of insomnia (p value
Penggunaan Jasa Freight Forwarder Internasional Untuk Ekspor Benih Lobster Dari Perspektif Hukum Persaingan Usaha
Authors: Yetti Yetti , Indra Afrita  , Deddy Felandry  
Published: July 2021

Permasalahan adalah bagaimana Penggunaan Jasa Internasional Freight Forwarder untuk Ekspor Benih Lobster Dalam Perpektif Hukuim Persaingan Usaha bagaimana Akibat Hukum dan Penggunaan Jasa Internaional Freight Forwarder ini. Metode penelitian bersifat yuridis normatif, yang menganalisis dugaan pelanggaran undang-undang anti monopoli dengan cara bersekongkol dan memonopoli pengiriman benih lobster, dengan sumber datanya Bahan Hukum Primer, Bahan Hukum Sekunder dan Bahan Hukum Tertier. Teknik Pengumpulkan Data adalah Studi Kepustakaan, dan analisis data dengan diskriptif analisis. Hasil penelitian adalah bahwa PT ACK, selaku freght forwarder telah melakukan dugaan pelanggaran terhadap Pasal 17 tentang monopoli dan Pasal 24 persekongkolan dengan dua perusahan lainnya yakni KKP, dan Ketua Asosiasi Pengusaha Lobster Indonesia. Akibat hukumnya dengan adanya tindakan tersebut mengakibatkan terhalangnya para pelaku usaha pesaing PT ACK untuk menawarkan jasa kargo angkutan ekspor benih lobster ke luar negeri, tindakan dugaan pelanggaran yang dilakukan tiga pihak tersebut dapat dikenakan denda bagi pelaku monopoli dan persekongkolan ini berdasarkan Undang-Undang No. 11 tahun 2020 tentang Cipta Kerja yakni minimal Rp1 miliar.
Hydroxide Salts in the Clouds of Venus: Their Effect on the Sulfur Cycle and Cloud Droplet pH
Authors: Rimmer Paul B. , Jordan Sean , Constantinou Tereza , Woitke Peter , Shorttle Oliver , Hobbs Richard , Paschodimas Alessia 
Published: July 2021

Abstract
The depletion of SO2 and H2O in and above the clouds of Venus (45–65 km) cannot be explained by known gas-phase chemistry and the observed composition of the atmosphere. We apply a full-atmosphere model of Venus to investigate three potential explanations for the SO2 and H2O depletion: (1) varying the below-cloud water vapor (H2O), (2) varying the below-cloud sulfur dioxide (SO2), and (3) the incorporation of chemical reactions inside the sulfuric acid cloud droplets. We find that increasing the below-cloud H2O to explain the SO2 depletion results in a cloud top that is 20 km too high, above-cloud O2 three orders of magnitude greater than observational upper limits, and no SO above 80 km. The SO2 depletion can be explained by decreasing the below-cloud SO2 to 20 ppm. The depletion of SO2 in the clouds can also be explained by the SO2 dissolving into the clouds, if the droplets contain hydroxide salts. These salts buffer the cloud pH. The amount of salts sufficient to explain the SO2 depletion entails a droplet pH of ∼1 at 50 km. Because sulfuric acid is constantly condensing out into the cloud droplets, there must be a continuous and pervasive flux of salts of ≈10−13 mol cm−2 s−1 driving the cloud droplet chemistry. An atmospheric probe can test both of these explanations by measuring the pH of the cloud droplets and the concentrations of gas-phase SO2 below the clouds.
A Highly Complex, MHC-Linked, 350 Million-Year-Old Shark Nonclassical Class I Lineage
Authors: Almeida Tereza , Ohta Yuko , Gaigher Arnaud , Muñoz-Mérida Antonio , Neves Fabiana , Castro L Filipe C , Machado André M , Esteves Pedro J , Veríssimo Ana , Flajnik Martin F 
Published: July 2021

Abstract
Cartilaginous fish, or Chondrichthyes, are the oldest extant vertebrates to possess the MHC and the Ig superfamily–based Ag receptors, the defining genes of the gnathostome adaptive immune system. In this work, we have identified a novel MHC lineage, UEA, a complex multigene nonclassical class I family found in sharks (division Selachii) but not detected in chimaeras (subclass Holocephali) or rays (division Batoidea). This new lineage is distantly related to the previously reported nonclassical class I lineage UCA, which appears to be present only in dogfish sharks (order Squaliformes). UEA lacks conservation of the nine invariant residues in the peptide (ligand)–binding regions (PBR) that bind to the N and C termini of bound peptide in most vertebrate classical class I proteins, which are replaced by relatively hydrophobic residues compared with the classical UAA. In fact, UEA and UCA proteins have the most hydrophobic-predicted PBR of all identified chondrichthyan class I molecules. UEA genes detected in the whale shark and bamboo shark genome projects are MHC linked. Consistent with UEA comprising a very large gene family, we detected weak expression in different tissues of the nurse shark via Northern blotting and RNA sequencing. UEA genes fall into three sublineages with unique characteristics in the PBR. UEA shares structural and genetic features with certain nonclassical class I genes in other vertebrates, such as the highly complex XNC nonclassical class I genes in Xenopus, and we anticipate that each shark gene, or at least each sublineage, will have a unique function, perhaps in bacterial defense.
Protein Kinase CK2 Regulates B Cell Development and Differentiation
Authors: Wei Hairong , Yang Wei , Hong Huixian , Yan Zhaoqi , Qin Hongwei , Benveniste Etty N 
Published: July 2021

Abstract
Protein kinase CK2 (also known as Casein Kinase 2) is a serine/threonine kinase composed of two catalytic subunits (CK2α and/or CK2α′) and two regulatory CK2β subunits. CK2 is overexpressed and overactive in B cell acute lymphoblastic leukemia and diffuse large B cell lymphomas, leading to inappropriate activation of the NF-κB, JAK/STAT, and PI3K/AKT/mTOR signaling pathways and tumor growth. However, whether CK2 regulates normal B cell development and differentiation is not known. We generated mice lacking CK2α specifically in B cells (using CD19-driven Cre recombinase). These mice exhibited cell-intrinsic expansion of marginal zone B cells at the expense of transitional B cells, without changes in follicular B cells. Transitional B cells required CK2α to maintain adequate BCR signaling. In the absence of CK2α, reduced BCR signaling and elevated Notch2 signaling activation increased marginal zone B cell differentiation. Our results identify a previously unrecognized function for CK2α in B cell development and differentiation.
Методичний підхід до кількісного оцінювання спроможностей медичних підрозділів Збройних Сил України
Authors: Zui Y. O. 
Published: July 2021

Вступ. У статті запропоновано методичний підхід до модульного кількісного оцінювання спроможностей медичних підрозділів Збройних Сил України, в основу якого покладено модульний підхід до побудови та оцінювання медичних підрозділів, що застосовується у Північноатлантичному Альянсі. Аналіз затверджених методів оцінювання спроможностей дозволив зробити висновки про необхідність розробки та впровадження до практики ЗС України модульного оцінювання функціонування медичних підрозділів з використанням принципів багатокритеріальної оптимізації.
Мета. Розробити можливі підходи до кількісного оцінювання спроможностей медичних підрозділів ЗС України та їх функціональних модулів.
Матеріали та методи. Бібліосемантичний, системного аналізу та підходу, концептуального моделювання, медико-статистичний.
Результати. Мета медичного забезпечення збройних сил досягається виконанням сукупності завдань для вирішення яких існують медичні підрозділи, заклади та керівні медичні органи. Постає необхідність визначення таких завдань, які були б реальні для виконання в умовах впливу зовнішніх та внутрішніх факторів, та з іншої сторони – забезпечували необхідний рівень надання медичного забезпечення основних сил. Оскільки медичне забезпечення є багатокомпонентною системою з безліччю критеріїв та показників, постає проблема в об’єктивному порівнянні рівня набутих медичними підрозділами спроможностей з необхідними. Практика країн, що запровадили на державному рівні оборонне планування на основі спроможностей, показує, що стандартизація модульної побудови медичних підрозділів збройних сил та оцінювання спроможностей за елементами системи DOTMLPF-I забезпечує високу готовність підрозділів, більш ефективну та гнучку роботу під час виконання покладених на них завдань. Якісне, обґрунтоване та стандартизоване оцінювання спроможностей дасть змогу виявляти ризики, мінімізувати суб’єктивне тлумачення вимог до спроможностей та наблизити функціональну, організаційну та ресурсну сумісність медичних підрозділів Сил оборони України та Північноатлантичного альянсу. Зазначене вище актуалізує необхідність розробки методології оцінювання спроможностей медичних підрозділів ЗС України наближеної до стандартів НАТО.
Висновки. Незважаючи на те, що у ЗС України вже багато років триває робота стосовно набуття взаємосумісності з державами‐членами НАТО, розробки доктрини з оцінювання та методичних рекомендацій з оцінювання (сертифікації), дослідження питань оборонного планування на основі спроможностей та проблем оцінки спроможностей досліджена недостатньо. Робота з розробки методів оцінювання спроможностей медичних підрозділів триває і досі. В результаті системного аналізу виявлено значні відмінності в рівнях оцінювання спроможностей медичного забезпечення збройних сил, функціональній побудові медичних підрозділів та розбіжності в критеріях оцінювання спроможностей, що дозволяє запропонувати методичний підхід щодо оцінювання.