bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cardiovascular health indicators in soccer exercise during adolescence: systematic review
Authors: Nunes Heloyse Elaine Gimenes , Faria Evelinn Amarilha , Martinez Paula Felippe , Oliveira-Júnior Silvio Assis de 
Published: April 2021

Abstract
This review analyzed the studies that evaluated cardiovascular health indicators (blood pressure, waist circumference, heart rate, glucose index and lipid blood) in recreational soccer players during adolescence, and identify possible associated factors. The search was performed in the electronic databases (PubMED, SciELO, LILACS, Scopus, SPORTDiscus and Web of Science). Inclusion criteria were: population composed of children and/or adolescents (10–19 years or average age up to 19 years); studies adolescents engaged in recreational soccer regularly and observational studies with cross-sectional or longitudinal design. The process of analysis of studies involved reading titles, abstracts and full texts. After these phases, seven articles were eligible. Regarding the design, all studies were cross-sectional. Of the total studies included, five presented moderate methodological quality values and two presented low methodological quality values, according to National Heart, Lung, and Blood Institute instrument. The most cardiovascular health indicators used in recreational soccer players during adolescence was waist circumference; three studies analyzed heart rate, two evaluated blood pressure, one analyzed insulin resistance and none of the included studies analyzed lipid profile. Factors associated were analyzed in four studies, being that sedentary time and body mass index (BMI) present association with at least one indicator of cardiovascular health.
Liraglutide combined with intense lifestyle modification in the management of obesity in adolescents
Authors: Apperley Louise J. , Gait Lucy , Erlandson-Parry Karen , Laing Peter , Senniappan Senthil 
Published: April 2021

Abstract

Objectives
Childhood obesity is a public health concern worldwide, with rates continuing to rise, despite preventive measures. Lifestyle modification remains the mainstay in the treatment of patients with excessive weight, but unfortunately, this is not always successful. Options for medical management of obesity in the paediatric population are limited.

Methods
Seven adolescents (all girls, mean age 14.9 years) with a body mass index (BMI) above 98th percentile and serious complications secondary to obesity were offered an intense weight management programme. The participants were reviewed by a multidisciplinary team every two weeks for advice and support, and treated with daily subcutaneous injections of liraglutide (dose range 1.2–3.0 mg). Scores for anxiety and depression were evaluated using the Revised Child Anxiety and Depression Scale.

Results
The results showed a significant weight loss over the three months with an average reduction of 5.4 kg (4.2%; 95% CI 1.93–8.78; p=0.0087). The mean drop in BMI was 2.1 kg/m2, which is statistically significant (95% CI 0.973–3.199; p=0.0037). Resolution of complications (raised intracranial pressure and steatohepatitis) was noted following weight loss. Anxiety and depressive symptoms improved over the three-month intervention course, especially features of separation anxiety disorder. Liraglutide was well tolerated by all patients.

Conclusions
Liraglutide medication, alongside a dedicated multidisciplinary team guided lifestyle therapy, is effective and safe in the treatment for excessive weight in adolescents, leading to the reversal of the complications related to obesity and improvement in the psychological symptoms.
The utility of reverse phenotyping: a case of lysinuric protein intolerance presented with childhood osteoporosis
Authors: Avci Durmusalioglu Enise , Isik Esra , Ayyildiz Emecen Durdugul , Goksen Damla , Ozen Samim , Onay Huseyin , Kose Melis , Atik Tahir , Darcan Sukran , Cogulu Ozgur , Ozkinay Ferda 
Published: April 2021

Abstract

Objectives
Childhood osteoporosis is often a consequence of a chronic disease or its treatment. Lysinuric protein intolerance (LPI), a rare secondary cause of the osteoporosis, is an autosomal recessive disorder with clinical features ranging from minimal protein intolerance to severe multisystemic involvement. We report a case diagnosed to have LPI using a Next Generation Sequencing (NGS) panel and evaluate the utility of reverse phenotyping.

Case presentation
A fifteen-year-old-boy with an initial diagnosis of osteogenesis imperfecta, was referred due to a number of atypical findings accompanying to osteoporosis such as splenomegaly and bicytopenia. A NGS panel (TruSight One Sequencing Panel) was performed and a novel homozygous mutation of c.257G>A (p.Gly86Glu) in the SLC7A7 gene (NM_001126106.2), responsible for LPI, was detected. The diagnosis was confirmed via reverse phenotyping.

Conclusions
Reverse phenotyping using a multigene panel shortens the diagnostic process.
Is overweight/obesity a risk factor for atopic allergic disease in prepubertal children? A case–control study
Authors: Vehapoglu Aysel , Cakın Zeynep Ebru , Kahraman Feyza Ustabas , Nursoy Mustafa Atilla , Toprak Ali 
Published: April 2021

Abstract

Objectives
It is unclear whether body weight status (underweight/normal weight/overweight/obese) is associated with allergic disease. Our objective was to investigate the relationship between body weight status (body mass index; BMI) and atopic allergic disease in prepubertal children, and to compare children with atopic allergic diseases with non atopic healthy children.

Methods
A prospective cross sectional study of 707 prepubertal children aged 3–10 years was performed; the participants were 278 atopic children with physician-diagnosed allergic disease (allergic rhinitis and asthma) (serum total IgE level >100 kU/l and eosinophilia >4%, or positivity to at least one allergen in skin test) and 429 non atopic healthy age- and sex-matched controls. Data were collected between December 2019 and November 2020 at the Pediatric General and Pediatric Allergy Outpatient Clinics of Bezmialem Vakıf University Hospital.

Results
Underweight was observed in 11.6% of all participants (10.8% of atopic children, 12.2% of healthy controls), and obesity in 14.9% of all participants (18.0% of atopic children, 12.8% of controls). Obese (OR 1.71; 95% CI: 1.08–2.71, p=0.021), and overweight status (OR 1.62; 95% CI: 1.06–2.50, p=0.026) were associated with an increased risk of atopic allergic disease compared to normal weight in pre-pubertal children. This association did not differ by gender. There was no relationship between underweight status and atopic allergic disease (OR 1.03; 95% CI: 0.63–1.68, p=0.894).

Conclusions
Overweight and obesity were associated with an increased risk of atopic allergic disease compared to normal weight among middle-income and high-income pre pubertal children living in Istanbul.
Selected types of corrosion degradation of pipelines
Authors: Hagarová M.  , Cervová J. , Jaš F. 
Published: April 2021

Abstract
The paper deals with corrosion degradation of gas pipeline.
Pipelines play very important role as means transporting
gas media over long distances from producers to end-users.
Gas pipelines present a risk of potential corrosion degradation
that can result in their failure. Corrosion on internal surfaces
of steel pipes takes place in CO2, H2S, H2O and chloride environment.
Degradation of steel results in loss of mechanical
properties, reduction in thickness and ultimate perforation and
failure. Corrosion is the electrochemical process that involves
the fl ow of electrical currents on a micro or macro scale. For
corroding steel, the anodic and the cathodic reactions produces
the electrochemical cell. Corrosion protection of internal
pipeline surface is based mainly on chemical composition of
gas and the use of inhibitors. Corrosion protection of the external
steel surface of the product line involves coatings and
cathodic protection.
„Ut unum sint“ – eine bleibende Herausforderung nach 25 Jahren
Authors: Neumann Burkhard 
Published: April 2021

Zusammenfassung
In seiner 1995 veröffentlichten Enzyklika „Ut unum sint“ über den Einsatz für die Ökumene macht Papst Johannes Paul II. deutlich, dass sich die römisch-katholische Kirche mit dem II. Vatikanischen Konzil „unumkehrbar“ auf den Weg der Ökumene begeben hat. Vor allem die von ihr ausdrücklich angestoßene Debatte über ein ökumenisch tragfähiges Petrusamt ist bis heute nicht überholt, sondern weiterhin aktuell. Darüber hinaus führt die Enzyklika etwa mit der Betonung des gegenseitigen Lernens, ihrer Theologie des Dialogs oder dem Verweis auf die Ökumene der Märtyrer über die Aussagen des Konzils hinaus und bleibt so eine Herausforderung für den ökumenischen Weg nicht nur der römisch-katholischen Kirche.
The Effect of Mentoring on Employee Job Performance in the Nigerian Service Sector
Authors: Oladimeji Moruff Sanjo , Sowemimo Olatunji Zacchaeus 
Published: April 2021

Abstract
The business world is changing due to the occupational climate and a large proportion of business executives that are bound to retire in the nearest future leading to an anticipated great loss of knowledge and performance. The paper seeks to evaluate job performance by considering the effect of mentoring on employee performance in the Nigerian service sector. Research focuses on finding out the level at which exposure, counseling, and role modelling affect employee performance in the Nigerian service sector.
Psychological Capital (PsyCap) Resources and its Relations with Creative Self-efficacy in Entrepreneurship Students
Authors: Savickaitė-Kazlauskė Evelina 
Published: April 2021

Abstract
This study aims to analyse Psychological Capital (PsyCap) and creative self-efficacy of students participating in the entrepreneurship program. The theory of the paper analyses the development and significance of concepts. Quantitative research focuses on finding out the levels of PsyCap and creative self-efficacy, comparing PsyCap data to a representative sample, comparing all results with the current job status and their entrepreneurial intentions.
Effects of calcium silicate synthesized in situ on Fiber loading and paper properties
Authors: An Yongzhen , Liu Haitang , Liu Jing , Li Xuexiu , Li Jie , Chen Lin , Jin Xin , Xu Yan , Zhao Zhiqiang , Song Shunxi , Hui Lanfeng , Liu Zhong , Huang Yingjian 
Published: April 2021

Abstract
The in-situ synthesis of calcium silicate in the fiber can not only meet the requirements for high loading of paper, but also make up and improve the reduction of paper performance caused by filling. In this investigation, the effects of pulp type, beating degree, fiber ratio, reaction time, rotational speed, dosage of lime milk and dispersant on calcium silicate loading and paper properties were investigated. The results showed that when the beating degree was 40 °SR, the ratio of softwood and hardwood pulp was 1:1, the reaction time was 60 min, the rotation speed was 600 r·min−1, the dosage of lime milk was 1.33 times of the theoretical amount, and the dosage of cationic polyacrylamide was 0.3 % (absolutely dry pulp), the ash content of hand-made sheet was 41.2 %, and the loading amount of calcium silicate was 26.3 %. Under this condition, the comprehensive performance of paper was the best.
Synthesis of a new organic probe 4-(4 acetamidophenylazo) pyrogallol for spectrophotometric determination of Bi(III) and Al(III) in pharmaceutical samples
Authors: Ammar Jumana W. , Khan Zainab A. , Ghazi Marwa N. , Naser Naser A. 
Published: April 2021

Abstract
A modern development discusses the synthesis and validity of simple, sensitive, and versatile spectrophotometric methods for Bi(III) and Al(III) determination in pharmaceutical formulations have been conducted. In the present paper, 4-(4 acetamidophenylazo) pyrogallol has been synthesized as a new organic compound, 4-APAP, by coupling pyrogallol in a regulated pH medium with diazotized p-aminoacetanilide. 4-APAP was identified by methods of FT-IR, 1H-NMR, 13C-NMR, and thermal analysis (thermogravimetry and differential scanning calorimetry). Solvatochromic activity was also studied in solvents with different polarities. The Kamlet and Taft linear solvation energy relationship was used to correlate shifts in UV-Visible spectra of 4-APAP with Kamlet-Taft parameters (α, β, and π*). The optimum assay conditions showed linearity from 0.3–13 to 0.5–11 μg·mL−1 for Bi(III) and Al(III), respectively. Molar absorptivity values were 3.365 × 104 and 0.356 × 104 L·mol−1·cm−1 for Bi(III) and Al(III), with similar Sandell's sensitivity measures of 0.006 and 0.008 μg·cm−2. Detection limits and quantification limits were 0.013 and 0.043 μg·mL−1 for Bi(III), respectively, and 0.018 and 0.059 μg·mL−1 for Al(III) with the relative standard deviation for determination of both metal ions using 4-APAP probe being <2.0%. The validity, accuracy, and efficiency of the approaches were demonstrated by the determination of Bi(III) and Al(III) in different formulations.
Parasitic architecture
Authors: Baroš Tomáš , Katunský Dušan 
Published: April 2021

Abstract
This paper could be considered as a general overview of current examples of realization, research, in architecture which could be called parasitic. Also, as an outline of possible new perspectives on current issues through the biomimicry design philosophy. The aim was also to clearly articulate the intent of the research I am dealing with while opening up a discourse on the subject.
Drought indices and trend analysis
Authors: Nagy Patrik , Zeleňáková Martina 
Published: April 2021

Abstract
In recent times, extremely dry seasons have been occurring more and more often in the eastern Slovakia, alternating with extremely wet seasons like torrential floods from extreme rainfall. Trend of reconnaissance drought index (RDI) and streamflow drought index (SDI) was evaluated in the paper using the Mann-Kendall test. The indices were evaluated at six climatic and river stations in the eastern Slovakia. The Mann-Kendal test results showed that the trend in the SDI index is not significant in 5 stations and only in one station the trend is significant. In the RDI index the trend is not significant in four stations and the trend is significant in two stationshe abstract is to indicate the subject of the paper, how the author proposes to develop the subject and its overall objective, aim or outcome.
Evaluation of biological activities ofBarbarea integrifoliaand isolation of a new glucosinolate derivated compound
Authors: Badem Merve , Sener Sıla Ozlem , Kanbolat Seyda , Korkmaz Nuriye , Yildirmiş Sermet , Ozgen Ufuk , Aliyazicioglu Rezzan , Salva Emine , Kaban Kübra , Kandemir Ali , Calıs İhsan 
Published: April 2021

AbstractThe aim of the present study is to determine the potent biological activities and carry out isolation studies onBarbarea integrifolia. The antioxidant capacity of the species was evaluated by total phenolic content, FRAP, CUPRAC, and DPPH radical scavenging activity. Anticancer activity studies were performed by MTT assay in MDA-MB-231, MCF-7, Hep3B, PC-3, A549, HCT116, L-929 cell lines. It was observed that the remaining aqueous fraction has higher total phenolic content while higher activity in the CUPRAC and FRAP assays was displayed for the methanolic extract and chloroform fraction. The extracts showed anticancer activity as compared with vincristine. It was observed that chloroform fraction has the highest anticancer activity on MCF-7 cell line, while ethyl acetate fraction has the highest anticancer activity on Hep-3B and A549 cell lines. Methanolic extract has the highest anticancer activity on HCT116 and MDA-MB-23 cell lines. The isolation studies have been performed using several chromatographic methods. The chemical structures of compounds have been identified by means of1H NMR,13C NMR, 2D-NMR, and MS. Five major compounds, one steroid (β-Sitosterol), one phenolic acid (Rosmarinic acid), one flavonol heteroside (kaempferol 7-O-α-l-rhamnoside-3-O-β-d-(2-O-β-d-glucosyl)-β-d-glucoside), and two glucosinolates (Gluconasturtiin, Gluconasturtiin choline salt) have been isolated.
Advantages of functional analysis in comparison of different chemometric techniques for selecting obesity-related genes of adipose tissue from high-fat diet-fed mice
Authors: Dharmaraj Saravanan , Mahadeva Rao U. S. , Simbak Nordin 
Published: April 2021

Introduction: Obesity is a lifestyle disease that is becoming prevalent nowadays and is associated with a surplus in energy balance related to lipid metabolism, inflammation and hypoxic condition, resulting in maladaptive adipose tissue expansion. This study used the publicly available gene dataset to identify a small subset of important genes for diagnostics or as potential targets for therapeutics.
Methods: Chemometric analyses by principal component analysis (PCA), random forest (RF), and genetic algorithm (GA) were used to identify 50 genes that differentiate adipose samples from high-fat diet- and normal diet-fed mice. The first 30 important genes were studied for classifying the samples using six different classification techniques. Gene ontology (GO), pathway analysis, and protein-protein interaction studies on the 50 selected genes were subsequently done to identify important functional genes. Finally, gene regulatory effects by microRNA were assessed to confirm the genes’ potential as targets for new therapeutic drugs.
Results: The genes identified by RF are best for differentiating the samples, followed by PCA, with the least predictability shown by genes chosen by GA. However, PCA identified more genes with functional importance, such as the hub genes ATP5a1 and Apoa1. ATP5a1 is the main hub gene, whereas Apoa1 is involved in cholesterol metabolism. Vapa and Npc2 are crosstalk genes that link both of these main genes and could be targeted for therapeutic drug design.
Conclusion: The combination of different chemometric techniques and functional analysis of genes could be used to select for a small number of genes which could serve as more suitable diagnostic or therapeutic targets.
First record of Ubaghsicystis (Eocrinoidea - Echinodermata) from the Cambrian (Miaolingian, Wuliuan) of Sonora, Mexico: Biostratigraphical and paleoecological considerations
Authors: Buitrón-Sánchez Blanca-Estela ,  Cuen-Romero Francisco-Javier , Beresi Matilde-Sylvia , Monreal Rogelio 
Published: April 2021

Introduction: The present work constitutes the first record of Ubaghsicystis Gil-Cid & Domínguez-Alonso (Echinodermata-Eocrinoidea) in the El Gavilán Formation, exposed in the El Sahuaral Hill, a new Cambrian locality of central Sonora, Mexico. The El Gavilán Formation is a sedimentary sequence mainly made up of shale interbedded with limestone, with abundant invertebrate fossils, deposited in an open shelf marine environment. Objective: The main objective of this research work is to describe the species Ubaghsicystis cf. U. segurae for the first time in Mexico, in addition to biostratigraphic and paleoecological considerations. Methods: A composite stratigraphic section of the El Gavilán Fm. was measured in central Sonora, where samples corresponding to eocrinods were collected, the material was examined in the Microscope Leica MZ10. Results: The biotic association is composed of reticulosan sponges, chancelloriids (Chancelloria eros, Allonnia tintinopsis, Archiasterella sp.), hyolithids, brachiopods, trilobites (Quadragnostus depressa, Peronopsis sp., Tonkinella valida, and Elrathina sp.), and echinoderms (Ubaghsicystis cf. U. segurae). Regarding the age, the trilobite association establishes a chronostratigraphic position from the middle Cambrian (Miaolingian, Wuliuan), Altiocculus Subzone, Ehmaniella Zone. The material studied is constituted by isolated echinoderm plates, which probably represent various cycles of theca plates assigned to Ubaghsicystis cf. U. segurae. The genus Ubaghsicystis has been scarcely recorded in a few Cambrian regions (e.g., Burgess Shale in Canada and Los Barrios de Luna in Spain), so that the information about this taxon is limited. Conclusions: The Cambrian succession of Sonora, where Ubaghsicystis occurred, was part of the border from the Laurentia craton during this period, located near the Paleoequator during this period, where ideal conditions for increasing diversity and abundance of species were developed, including echinoderms.
Morphology of endoskeleton and spination in the sea star Midgardia xandaros (Brisingida: Brisingidae) from the Gulf of Mexico
Authors: Esteban-Vázquez Brenda-Lizbeth , De-los-Palos-Peña Magdalena , Solís-Marín Francisco-Alonso , Laguarda-Figueras Alfredo 
Published: April 2021

Introduction. The deep-sea asteroid species of Brisingida have a nearly global distribution but have remained poorly understood due to their deep bathymetric distributions and fragile skeletons. Objective. To describe the external and internal morphology of Midgardia xandaros including the skeletal arrangement, through multifocal and SEM techniques. Methods. We examined a total of 21 specimens, including 27 arm fragments, from the Gulf of Mexico and Honduras. Two specimens were dissected. Results. Detailed descriptions of pedicellariae, abactinal, intercostal, inferomarginal, adambulacral, ambulacral, odontophore, and oral ossicles, and their spines are provided, emphasizing the articulations and muscle attachments. C-shaped valves pedicellariae and small pedicellariae valves with shorter denticulation areas were recognized. Conclusions. The morphological description of M. xandaros is expanded, providing the most extensive description of abactinal, first adambulacral, first and subsequent inferomarginal ossicles, abactinal spines, and C-shaped, crossed pedicellariae, as well as the distal arm plates, for a brisingid species using SEM to date.
Integrated cooling solution for concentrator photovoltaic cells
Authors: Rózsás Gábor , Bognár György , Takács Gábor , Plesz Balázs 
Published: April 2021

AbstractThe efficiency of the most modern photovoltaic cells currently reaches 40–45%, which is achieved by concentrator systems. However, despite better device efficiencies concentrator photovoltaic cells have major drawback, namely the high amount of waste heat, which requires new cooling solutions.This paper gives a short overview of the current cooling techniques and proposes a novel microchannel cooling solution for concentrator photovoltaic cells. In the concept, the microscale channels are integrated into the backside metallization of the PV device. The paper gives a description of the technological process that can be used to produce microchannels on the back of solar cells and shows the optimization of the channels to achieve optimal cooling performance.