bluuebunny/crossref_metadata_2025_split huggingface dataset:
Empathy Among Orthopaedic Surgery Trainees
Authors: Sabharwal Samir , Lin Carol , Weistroffer Joseph K. , LaPorte Dawn M. ,   and the Collaborative Orthopaedic Educational Research Group
Published: September 2021

Background:
It has been postulated that the process of—and stresses associated with—medical training may cause a loss of empathy among trainees. Because empathy is considered an important value for clinicians and may even be associated with better patient outcomes, we assessed the empathy of orthopaedic surgery trainees and identified factors associated with empathy.

Methods:
Between June and September 2020, an anonymous survey was distributed electronically to trainees in 23 Accreditation Council for Graduate Medical Education-accredited orthopaedic surgery residency programs via the Collaborative Orthopaedic Educational Research Group. The survey comprised the validated Short-Form 8-Item Empathy Quotient (EQ-8) questionnaire—scored on a scale of 0, least empathetic, to 16, most empathetic—and single-item measure of emotional exhaustion and depersonalization derived from the Maslach Burnout Index—scored using a frequency scale. In total, 438 of 605 (72%) trainees completed the survey. The scores were compared via one-way analysis of variance, with Bonferroni correction and Tukey post-hoc testing, α = 0.05.

Results:
The mean (±SD) EQ-8 score among respondents was 11.3 ± 3.3. Women scored significantly higher (mean, 12.2 ± 2.8) than men (mean, 11.2 ± 3.3) (p = 0.02). Mean scores were significantly higher for trainees planning on a career in academic medicine (12.0 ± 2.9) than those intending to pursue private practice (10.9 ± 3.3) or those with a military commitment (10.4 ± 3.4) (p = 0.01). An inverse relationship was found between EQ-8 scores and single-item Maslach Burnout Index measures in depersonalization and emotional exhaustion (both, p < 0.01). No significant differences were found in EQ-8 scores across postgraduate year, program location, primary training setting, intended fellowship, relationship status, or whether they reported having children.

Conclusions:
We found no association between postgraduate year and EQ-8 score. Women and those intending to pursue a career in academic medicine had significantly higher levels of empathy. A significant inverse relationship was found between burnout and empathy. Respondents with higher levels of emotional exhaustion and depersonalization had lower levels of empathy.
Patient Satisfaction, Functional Outcomes, and Implant Survivorship in Patients Undergoing Customized Cruciate-Retaining TKA
Authors: Schroeder Lennart , Pumilia Cyrus Anthony , Sarpong Nana O. , Martin Gregory 
Published: September 2021

Background:
Customized total knee arthroplasty (C-TKA) systems are becoming increasingly popular in patients with end-stage knee arthritis. Manufactured with use of patient data derived from computed tomography or magnetic resonance imaging, these systems aim to restore the individual bone anatomy of the patient by providing customized fit and geometries. This retrospective study investigated implant survivorship, patient satisfaction, and functional outcomes following C-TKA with a cruciate-retaining prosthesis.

Methods:
We retrospectively reviewed data from 540 knees in 433 patients who underwent C-TKA performed by a single surgeon at a single institution. Patient demographics, surgical variables, complications, and reoperations were evaluated. Follow-up evaluations were performed via a single telephone call to assess patient satisfaction, functional outcomes according to the Knee injury and Osteoarthritis Outcome Score for Joint Replacement (KOOS-JR) questionnaire, and implant survivorship following C-TKA. Descriptive statistics were analyzed.

Results:
At the time of C-TKA, the mean age was 71.8 years and the mean body mass index was 29.1 kg/m2. The mean follow-up was 2.8 years. Patient satisfaction was high, with 89% of C-TKA patients being either satisfied or very satisfied. The mean KOOS-JR was 82. There were 8 revisions (1.5%) at an average of 0.7 years after the index C-TKA; hence, there was an implant survivorship of 98.5%.

Conclusions:
To our knowledge, this was the largest retrospective study to date to report on patient satisfaction, functional outcomes, and implant survivorship following C-TKA. We observed a high satisfaction rate, satisfactory functional outcomes, and high implant survivorship at midterm follow-up.

Level of Evidence:
Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.
Conversion Total Knee Arthroplasty
Authors: Ramamurti Pradip , Fassihi Safa C. , Stake Seth , Stadecker Monica , Whiting Zachariah , Thakkar Savyasachi C. 
Published: September 2021

» Conversion total knee arthroplasty (TKA) represents a heterogeneous group of procedures and most commonly includes TKA performed after ligamentous reconstruction, periarticular open reduction and internal fixation (ORIF), high tibial osteotomy (HTO), and unicompartmental knee arthroplasty (UKA).» Relative to patients undergoing primary TKA, patients undergoing conversion TKA often have longer operative times and higher surgical complexity, which may translate into higher postoperative complication rates.» There is mixed evidence on implant survivorship and patient-reported outcome measures when comparing conversion TKA and primary TKA, with some studies noting no differences between the procedures and others finding decreased survivorship and outcome scores for conversion TKA.» By gaining an improved understanding of the unique challenges facing patients undergoing conversion TKA, clinicians may better set patient expectations, make intraoperative adjustments, and guide postoperative care.
The “9.9 Super Shopping Day” Advertisement Video and Its Impact on Shopee Users on TikTok
Authors: Amrudhia Nada Farah , Nurfebiaraning Sylvie 
Published: September 2021

The research objective of this study is to find out the influence and how much the influence of Shopee’s In-Feed Native Video Ad on TikTok App toward Audience Attitude. This study focuses on Shopee’s In-Feed Native Video advertising “9.9 Super Shopping Day” version on TikTok by involving one independent variable which is advertising (Variable X) measured using sub variables which are heard word, color, music, picture, seen word and movement. Dependent variable which is Audience Attitude (Variable Y) measured with cognitive,affective and conative aspect. The method used in this study is quantitative with data collection techniques through surveys to 400 respondents, which are followers of the @shopee_id account on the TikTok application. The results showed that the influence of the Advertising variable (X) on the Audience Attitude variable (Y) was 58,6%. While the remaining 41,4% is influenced by other factors not examined. The t test results show that the advertising variable (X) has a t value greater than the t table value because t count (23.742)> t table (1.96),then H0 is rejected and H1 is accepted. This means that Shopee’s In-Feed Native Video Ad “9.9 Super Shopping Day” version on TikTok App have an impact on audience attitude.
Correlation Between Personal Hygiene And Hemoglobin Levels On Typhoid Fever Suspect Patients At Lirboyo General Hospital
Authors: Farodis Indana , Purnadianti Mely 
Published: September 2021

Personal Hygiene is an effort made by individuals in maintaining personal hygiene to avoid disease. Personal Hygiene is closely related to typhoid fever, because its transmission can be through food and drinks which are contaminated with Salmonella typhi. WHO and UNICEF ​​on 2015 ranked Indonesia as the second worst sanitation country in the world after India. One of the laboratory tests which is used to observe anemia levels and polycythaemia is hemoglobin degree. The purpose of this study was to analyze the correlation between personal hygiene and hemoglobin levels on typhoid fever suspect patients at Lirboyo General Hospital. The research method used analytic survey with Cross Sectional Study approach and purposive sampling used as the sampling technique with 38 respondents. The results of the study mostly have worst personal hygiene quality of 31 people (81.6%) while respondents have good personal hygiene quality of 7 people (18.4%) and the of hemoglobin category on patients stated normal in 29 people (76.3%) while patients who have abnormal hemoglobin category in 9 people (23.7%). Based on statistical tests on personal hygiene by hemoglobin showed 0.876 p-value and > 0.05 sig value Conclusion which indicated no correlation between personal hygiene and hemoglobin on typhoid fever suspect at Lirboyo General Hospital.
In-Vitro Sunscreen Activity of White Turi Leaf Acetone (Sesbania grandiflora (L.) Pers.) Extract
Authors: Siroj Muhammad Said Agil , Rohmah Jamilatur 
Published: September 2021

Sunscreens are cosmetic preparations that protect the skin from exposure to UV radiation resulting in erythema , skin burning , aging and skin cancer. Leaf of Sesbania grandiflora (L.) Pers. contain phenolic compounds such as tannins and flavonoids which act as photoprotective . This research method is experimental with quantitative descriptive analysis. The purpose of research is to know the value of SPF, transmission erythema (% Te) and pigmentation (% Tp) of acetone extracts of Sesbania grandiflora (L.) Pers. using Spectrophotometry UV -Vis at a wavelength of 280-400 nm with intervals of 5 nm. This study variations in extract concentration were made 100, 200, 400, 600, 800 and 1000 ppm. The results showed the SPF value of extracts of all concentrations in a row was 1.9 ( minimum ); 3.6 ( minimum ); 15.9 ( moderate ); 56.3 ( high ); 133.9 ( high ); and 136.6 ( high ). The %Te value is 400 ppm ( fast tanning ), 600 ppm ( regular suntan ) and 1000 ppm ( extra protection ). The value of %Tp at all extract concentrations is included in the category total block .
Lethal Efficacy of Banana Leaves Extract (Musa paradisiaca L.) Against Aedes aegypti Larvae
Authors: Karima Wihdatul , Ardiansyah Syahrul 
Published: September 2021

Indonesia has a potential to be exposed to the threat of dengue hemorrhagic fever with the point vector, the Aedes aegypti mosquito, so development need to be stopped. The use of synthetic larvicides in eradicating mosquito larvae can cause environmental pollution. To reduce it, an alternative is needed using plant larvacides with banana leaf. Banana leaves are obtained from Candi Sidoarjo. Ethanol extract of banana leaf contains tannin compounds, alkaloids, terpenoids, saponins, and flavonoids which can be used as larvicides. This research was conducted to determine the toxic effects of banana leaf extract (Musa paradisiaca L.) on the larvae of Aedes aegypti mosquito mortality. This research was conducted using the post test only the control group design with 6 treatment groups including control (aquades) and banana leaf extract concentrations of 1000 ppm, 2000 ppm, 3000 ppm, 4000 ppm, 5000 ppm. This study used third instar larvae, each test group countaining 20 larvae with 4 repetitions. That obtained were analyzed using data and probit tests. The results of this study that banana leaf extract has a toxic effect on Aedes aegypti mosquito larvae with LC50 at a concentration of 4638 ppm.
Risk factors associated with spontaneous abortion in Dr. Soetomo General Hospital Surabaya: a case-control study
Authors: Zakira Safira , Hardianto Gatut 
Published: September 2021

The Maternal Mortality Ratio (MMR) in Indonesia is still fairly high. One of the top three causes of maternal death is bleeding. Spontaneous abortion is an early pregnancy problem leading to the occurrence of bleeding and direct maternal death. The causes of spontaneous abortion vary and can be caused by multiple factors. Early identification of risk factors is necessary to reduce mortality and morbidity due to spontaneous abortion and its complications. This study's objective was to identify the risk factors of spontaneous abortion in Dr. Soetomo General Hospital. This study was an observational analytic with a case-control approach. The population was all pregnant women hospitalized at the Obstetrics and Gynaecology Department in Dr. Soetomo General Hospital from January 2017 to December 2018. The samples were 120 in total, included 40 cases and 80 controls taken by consecutive sampling. The data were analyzed using univariate and bivariate analysis with the Chi-square test. The results based on the bivariate analysis showed history of previous abortion (p <0.001), chronic maternal disease (p <0.001), hemoglobin levels (p = 0.020), maternal age (p= 0.026), gravidity (p= 0.036), and infection (p= 0.037) had significant correlation with spontaneous abortion. In conclusion, risk factors associated with spontaneous abortion in Dr. Soetomo General Hospital were history of previous abortion, chronic maternal disease, anemia, advanced maternal age, multigravidity, and infection. Positive pregnancy outcomes are expected to play a role in reducing MMR in Indonesia. Therefore, high-risk pregnant women are suggested to carry out regular Antenatal care recommendations with intensive supervision.
Jurassic Provenance System and Its Geological Implication in Altyn Piedmont, Qaidam Basin
Authors: Zeng X. , Cao Q. , Wang B. , Hu C. , Tian J. X. , Zhu J. , Ouyang X. Q. 
Published: September 2021

AbstractA petroleum system originating from Jurassic source rocks exists in Altyn piedmont. However, the Jurassic formation in this system is deformed by Yanshan-Himalayan tectonic movement, and related studies about its spatial distribution and sedimentary system are still highly controversial. In general, a systematic research on the provenance system helps precisely restoring the prototype basin. Based on the methods of seismic characterization, sedimentary analysis, and detrital zircon U-Pb dating (samples from several Altyn piedmont outcrops), this paper studied the provenances of Jurassic formation in Altyn piedmont and characterized their distribution from different aspects: (1) Lacustrine rift basin developed in the study area at early Jurassic, while the formation showed a saucer shape with its thickness decreasing and vanishing towards the center of the basin in the middle Jurassic; in summary, the Jurassic formation in Altyn piedmont could be divided into several parts due to their different characteristics in different periods. (2) The south part of the Jurassic deposition (south of Qingshuigou) could come from the east Kunlun terrain; the middle part (Yueya mountain to Dongping area) however could be from several provenances, including the east Kunlun terrain, the surrounding plutons, and the Altyn fault; the north part (Niudong to north Lenghu area) is mainly related to the Altyn fault. (3) The Altyn fault, a regional fault system containing several strike-slip faults, is highly active since late Triassic and controls the current spatial distribution of the Jurassic formation; the faulted area in the piedmont could be separated into several parts with several different sources. (4) Compared to the southern and middle parts, the northern Jurassic deposition is relatively flat and contains wider and thicker source rock beds, which makes this area an important gas exploration target.
Novel Monitoring of the Core Body Temperature and Predictors of Hypothermia in Patients Undergoing Lung Cancer Surgery: A Prospective Observational Study
Authors: Liu Chang-qing , Lai Li , Ren Hong-fei , Wang Chen , Liu Yu-wei , Ni Zhao , Li Ka , Gong Ren-rong 
Published: September 2021

Abstract
Objectives: Our study aimed to explore the feasibility and effect of noninvasive and wireless intelligent monitoring of core body temperature in surgical patients, and to evaluate the effect of intraoperative hypothermia on rapid recovery index of the patients undergoing lung cancer surgery. Methods: From January 2020 to June 2020, a wireless temperature sensor was pasted onto the nonoperative side of the axilla preoperatively to monitor axillary temperatures to help estimate core temperature in lung cancer patients. The intraoperative body temperature changes and related factors were collected and analyzed. Independent associations between hypothermia exposure and the duration of hospitalization and direct medical costs were evaluated. Our research was carried out and report according to the STROBE guideline.Results: In total, 206 consecutive patients who underwent lung cancer surgery were recruited, and the incidence of hypothermia was 83.01%. The median proportion of patients experiencing hypothermia was 62.65%, with the largest decrease in temperature recorded as 1.034±0.569°C. The patients’ lowest body temperature was calculated as follows: (Y) = 35.423 - 0.003 × surgical duration + 0.045 × BMI - 0.012 × age, R2=0.182. Patients with hypothermia had longer hospital stays and higher medical costs (t=2.201, P=0.029 and t=5.048, P<0.001, respectively).Conclusions: Hypothermia contributes to extended hospital stays and increased medical costs for patients. The use of noninvasive and wireless intelligent monitoring throughout an operation and adoption of heat preservation measures are expected to prevent and reduce hypothermia and promote rapid patient recovery.
A-WDL: An Improved Recommendation Algorithm for WDL based on Attentional Mechanism Adaptation
Authors: Xu YuHao , Wang ZhenHai , Chen Hui 
Published: September 2021

Abstract
CTR prediction is one of the main research directions of recommendation algorithm, which is widely used in e-commerce advertising recommendation and other fields. Wide&Deep Learning (WDL) model is a CTR prediction and recommendation algorithm that combine linear model with deep neural network. To solve the problem that WDL is prone to over-fitting and the proportion of Wide and Deep learning part needs to be adjusted manually in practical application, Attentional WDL(A-WDL) algorithm is based on residual network to improve the Deep part. And use the attention mechanism to automate the learning of the Wide part and the Deep learning part of the proportion. Experiments on the public dataset Criteo on Kaggle show that the A-WDL algorithm improves the performance of AUC compared with other algorithms such as WDL, and effectively avoids the problem of overfitting. In addition, the performance improvement of A-WDL is explainable.
Effect of Trigonelline in a Model of Apoptosis in Rat Retina
Authors: Postacı Sevinç Arzu , Çeliker Ülkü , İlhan Nevin , Dağlı Ferda , Dal Ali 
Published: September 2021

Abstract
Purpose: To evaluate the efficacy of drop trigonelline and oral trigonelline (TG) treatment in a model of N-methyl D-aspartate (NMDA)-induced retinal apoptosis in rat retina. To compare with brimonidine tartrate (BT) drops with known retinal neuroprotective activity.Methods: 42 Wistar Albino male rats were randomly divided into 6 groups of 7 each. No action was applied to Group 1. Group 2 (negative control) was given intravitreal Phosphate Bufferd Saline (PBS) on the first day of the experiment and did not receive any treatment. Groups 3, 4, 5 and 6 were given intravitreal NMDA on the first day of the experiment. Group 3 (positive control) didn't receive post-injection treatment. For 21 days from the second day of the experiment, oral TG was given to group 4, TG drops were given group 5 and BT drops were given group 6. Histopathological and biochemical evaluations were performed in all groups.Results: Severe retinal degeneration was observed in group 3 compared to group 2 (p<0.001).There was no statistically significant difference between group 1 and group 2 (p>0.05). TUNEL, Brn3a and caspase3 staining in group 5 and group 6 were similar to group 2 (p>0.05). Group 5 and group 6 compared to group 3 were observed significant decrease in iNOS levels(p<0.05). Decreasing MDA levels and increasing SOD levels were detected in group 4,5,6 compared to group 3 (p<0.05).Conclusion: In our study, it was determined that TG drops showed similar retinal neuroprotective efficacy to BT drops.
Metabolic Analysis of the Regulatory Mechanism of Sugars on Secondary Flowering in Magnolia
Authors: Xuan Lingjuan , Wang Qianqian , Liu Zhigao , Cheng Shaoyu , Zhang Yingjia , Lu Danying , Dong Bin , Zhang Dongmei , Zhang Lang , Ma Jingjing , Shen Yamei 
Published: September 2021

Abstract
Background: Magnolia is a traditional and important ornamental plant in urban greening, which has been cultivated for about 2,000 years in China for its elegant flower shape and gorgeous flower color. Most varieties of Magnolia bloom once a year in the spring, whereas a few others, such as Magnolia liliiflora Desr. ‘Hongyuanbao’, also bloom for the second time in summer or a little late. Such a twice flowering trait is desirable because of its high ornamental values, but its underlying mechanism remains unclear. Results: To explore the peculiar metabolism twice-flowering in ‘Hongyuanbao’, the chemical metabolites and the relevant genes encoding them in the flower buds during the entire flowering period were analyzed. It appears that there was a significant variation between the metabolic profiles of flower differentiation between the first and secondary flower buds. The sucrose and trehalose metabolic pathways were significantly upregulated during both flowering periods as shown by a Kyoto Encyclopedia of Genes and Genomes pathway enrichment analysis. This was further verified by quantitative real-time polymerase chain reaction analysis which showed that the expression levels of a number of trehalose-6-phosphate synthase (TPS) genes including MlTPS1, MlTPS5, MlTPS6, MlTPS7, and MlTPS9 were substantial increased. To further investigate the potential functional role of sucrose and trehalose in flowering regulation, the leaves of ‘Hongyuanbao’ were sprayed with the sucrose or trehalose solution with a gradient of concentrations including 30 mM, 60 mM, and 90 mM. While both trehalose and sucrose of 60 mM in concentration were able to accelerate the process of flower bud differentiation, their molecular pathways appeared to be different. Sucrose treatment increased the transcription levels of MlTPS5 and MlTPS6, whereas trehalose treatment increased MlTPS1. The expression of a number of flowering-related genes, such as MlFT, MlLFY, and MlSPL was also increased in response to the sprays of sucrose and trehalose. Conclusions: Overall, the findings on the functional roles of sucrose/trehalose and their underlying molecular mechanism in flowering of ‘Hongyuanbao’ improves our current understanding on of the biochemical triggers for flowering in Magnolia and provides a useful tool in Magnolia cultivation and flowering management.