bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of two types of fixation for proximal tibial epiphysiodesis: An experimental study in a rabbit model
Authors: Bayrak Alkan , Duramaz Altuğ , Kızılkaya Cemal , Çelik Malik , Kural Cemal , Altınay Serdar , Kural Alev , Hakan Başaran Serdar 
Published: July 2021

Objectives: In this study, we describe a novel hemiepiphysiodesis technique to prevent implant-related perichondrial ring injury in a rabbit model.
Materials and methods: Proximal tibial epiphyseal plates of a total of 16 white New Zealand rabbits were used for this animal model. The subjects were divided into three equal groups as follows: Group 1 (Kirschner wire [K-wire]/cerclage), Group 2 (8-plate) right-hind legs, Group 3 (Control) left hind legs. Using anteroposterior radiography, the medial slope angle (MSA), articular line-diaphyseal angle (ALDA), and the angle between screws of 8-plate in lateral X-ray tibial slope angle (TSA) were measured. The radiographs were taken early postoperative (Day 1) and on sacrification day (Week 8). The histological evaluation of the perichondrial ring was made on a 7-mm axial section that stained with Safranin O/fast green at X10 magnification.
Results: In both K-wire and 8-plate groups, the early postoperative ALDA and TSA were greater than the sacrification ALDA and TSA (p=0.028 and p<0.001, respectively). The early postoperative MSA was lower than the sacrification MSA in groups, (p<0.001). The MSA in the control group was lower than the K-wire and 8-plate groups (p<0.001 and p=0.009; respectively). The perichondrial ring thickness of the K-wire group was greater than the 8-plate group in histological evaluation (p<0.001).
Conclusion: Both of the K-wire and 8-plate groups showed similar angulation effects in the proximal tibia, although histologically less damage to the perichondrial ring was observed in the K-wire group, compared to the 8-plate group.
The Historical Context of Judith Fetterley's The Resisting Reader: A Feminist Approach to American Fiction
Authors: Martin Wendy 
Published: July 2021

ABSTRACT
This essay provides historical context for the second wave of U.S. feminism, focusing on the decade before Judith Fetterley's The Resisting Reader was published. It demonstrates the ways in which Fetterley's book is shaped by and crystallized the development of feminist politics and scholarship during the decade.
Reading for Self-Defense
Authors: Hines Andy 
Published: July 2021

ABSTRACT
This essay traces the impact of the wider ideological landscape regarding “identity politics,” interpretive practice, and literature of the 1970s on Judith Fetterley's The Resisting Reader. Specifically, it tracks the traces of Black and women of color feminist organizing legible in Fetterley's text, as well as those left by social movements operating at the University of Pennsylvania in 1971. Though these traces go unattributed, this article argues that their presence offers an opportunity to read, as Fetterley might put it, a closed system from “without.” The author's resistant reading of Fetterley's text suggests how her “radical feminism” calls for a distinct attention to the materialist operations of academic and literary institutions in an investigation of their racialized, patriarchal power.
Socioeconomic role of women in the light of Islamic teachings and Constitution of Pakistan
Authors: Ashraf Maria , Rasheed Rizwan 
Published: July 2021

Pakistan is the sixth largest populated country estimated to have 200 million persons. Nearly half of its population is comprised of Women. Pakistani Women are contributing to advancement of this country by playing a vital role in core fields. But there are some areas where women are facing challenges like gender discrimination, limited access to education, domestic violence etc. Islam bestowed women a significance value in Islamic community. It is Islam that transforms women from symbol of shame to mark of an honor in Man dominated society. Beside this Glory there are also certain limits for women described by Islam. Muslim Women of Prophet Muḥammad (PBUH) era is the perfect exemplary Models for us. Besides being a dutiful Mother, Wife, Daughter and sister they did engage in worldly affairs too. It is true that home and family should be women’s first priority but in present time importance of women role cannot be denied in particular fields. Constitution of Pakistan provides equal rights to women. In 21st century we need a balanced and practical vision that ensures socio-economic development of Pakistani women without disturbing social Islamic structure. Briefly In this article these issues will be analyzed with practical approach by concluding applicable proposals.
Managerial capabilities and generic business strategies in the wineries of the 'Cava' protected designation of origin
Authors: Ferrer Juan R. 
Published: July 2021

Aim of study: Cava is Spain’s largest wine exporter. However, in the last 20 years, the growth of exports from Cava protected designation of origin (PDO) wineries has been lower than that of other Spanish PDO wines, and Cava’s domestic market share has fallen. From the point of view of strategic management, it could be said that it seems that the wineries of the Cava PDO are losing their competitive advantage. It is therefore fundamental to perform an analysis of the wineries that maintain a better performance to understand the elements that give them a competitive advantage. In this article, to analyse competitive advantage, both management capabilities and Robinson and Pearce’s generic business strategies are studied. The objective is twofold; on the one hand, we pursue the level of the managerial capabilities in the wineries of Cava PDO, while on the other hand, we seek to know the influence of the managerial capabilities and the strategies as reflected in their business performance.Area of study: Spanish wineries of the Cava PDO.Material and methods: Sixty-six wineries were analyzed using the Mann-Whitney U Test and Bayesian regression to determine the relationship between the managerial capabilities, strategy, and business performance.Main results: The results show a lower level of managerial capabilities in Cava PDO wineries as compared with Rioja PDO wineries, a strong relationship between management capabilities and performance.Research highlights: These results are highly applicable since they show what resources and what strategies should be promoted to achieve a competitive advantage.
Representaciones literarias de Campo de Gibraltar: demarcaciones, dinámicas y conflictos
Authors: Fuentes Felipe Oliver 
Published: July 2021

La frontera entre España y Marruecos es una de las más complejas y conflictivas del mundo contemporáneo. La disparidad económica entre Europa y África, las problemáticas locales de algunos municipios al sur de España, y la cercanía con Gibraltar y sus leyes fiscales a modo, suponen las condiciones idóneas para proliferación del tráfico de mercancía, drogas y personas. Esta realidad ha sido retratada por distintos novelistas. Este trabajo analiza tres ficciones españolas ambientadas en Campo de Gibraltar para analizar algunas problemáticas fronterizas concretas como la demarcación por <el exterior> y la demarcación por <el interior>, la transitoriedad de las dinámicas económicas y los límites de la ley para combatir al crimen organizado.
Biosimilar bidding in centralized tenders in Norway
Authors: Dalen Dag Morten , Strøm Steinar , Locatelli Marilena 
Published: July 2021

Our objective is to study the competition effect of biosimilar entry in centralized tenders for an expensive category or drugs - TNF-inhibitors. We use monthly observations of prices and volumes for all brands and biosimilars in this drug category in Norway, covering the period from Jan. 2006 to Dec. 2016. Descriptive statistics and regression models are used to investigate the impact of biosimilars on the drug price and the effect of the number of brands on the intensity of competition. Both the entry of biosimilars and new branded drugs have increased competition and reduced prices. According to our estimates, an increase in the market share of biosimilars from 10 % to 60 %, will be accompanied with a 50 % reduction in the expected price. Only two years after entry, the first biosimilars in this drug category had gained a market share of 40 % in Norwegian hospitals. Although entry barriers for biosimilars are higher than for generics of chemical substances, significant cost savings are expected from patent expirations of expensive biologics as well. The centralized design of the tenders is an important institutional factor behind the strong competition effect.
Published: Online January 2020
La mise à l’ordre du jour1 gouvernemental des enjeux de l’enseignement supérieur en français en Ontario de 2003 à 2020 : retour sur la création de l’Université de l’Ontario français
Authors: Cardinal Linda , Normand Martin 
Published: July 2021

En Ontario, la revendication pour la gouvernance francophone de l’enseignement universitaire a pris un nouvel élan dans les années 2000 pour aboutir, au mois de décembre 2017, à la création de l’Université de l’Ontario français (UOF). Toutefois, au mois de novembre 2018, le nouveau gouvernement conservateur au pouvoir provoque une onde de choc au sein de la population francophone lorsqu’il décide de retirer le financement prévu pour la mise en place de l’UOF. L’enjeu de l’enseignement supérieur en français redevient un problème public à résoudre. Heureusement l’UOF renaît dix-huit mois plus tard. Le texte a pour objectif d’étudier les processus de publicisation de l’enjeu de l’enseignement supérieur en français en Ontario depuis 2003 et sa mise à l’ordre du jour gouvernemental. L’article montre que la trajectoire conduisant à la création de l’UOF ne suit pas la séquence habituelle des mouvements engagés dans la résolution des problèmes publics. Au contraire, elle se démarque du fait qu’elle fait l’objet d’une série d’avancées et de reculs malgré sa résolution.
Université de l’Ontario français. Lorsqu’une vague médiatique soulève un enjeu de société
Authors: Lord François-René 
Published: July 2021

La création d’une nouvelle université au Canada est un phénomène peu commun. La fondation de l’Université de l’Ontario français (UOF), première université entièrement francophone en Ontario, revêt ainsi une importance primordiale pour la communauté franco-ontarienne, notamment pour la préservation de sa langue et de sa culture. L’annonce de l’abandon du financement de ce projet par le gouvernement progressiste-conservateur ontarien, le 15 décembre 2018, secoue cette population. Les médias canadiens traitent alors abondamment cette nouvelle. Nous proposons, dans cet article, une analyse à la fois quantitative et qualitative de 2405 articles de journaux couvrant cette période charnière dans la courte histoire de l’UOF. Notre étude révèle notamment que le journalLe Droit, le site de Radio-Canada et la plate-forme numérique ONfr+sont les médias ayant le plus traité de la création de l’UOF et qu’une plus grande proportion (60 %) des textes de notre corpus sont écrits en français. Le processus de médiatisation de l’UOF est marqué par une amplification médiatique de typemedia-hypeoù les journalistes utilisent la personnification, la représentation antagoniste des acteurs et le ton parfois émotif et acrimonieux pour cadrer la nouvelle.
Les effets de l’Université de l’Ontario français
Authors: Robichaud Jean-Bernard 
Published: July 2021

L’Université de l’Ontario français (UOF), arrachée de longue lutte par la communauté franco-ontarienne, aura des retombées positives sur le plan économique et sociétal pour le Centre-Sud-Ouest de l’Ontario, pour la province et pour la francophonie tout entière. Les retombées économiques seront significatives dès sa quatrième année d’opération, mais les retombées pour la société seront encore plus importantes. L’UOF a le potentiel de répondre aux attentes de sa loi constitutive de contribuer à l’épanouissement d’une « culture francophone forte, dynamique et inclusive » (Gouvernement de l’Ontario, 2017).
Faire face aux transformations dans l’enseignement supérieur : une conceptualisation des interactions entre différentes innovations pédagogiques
Authors: Bégin-Caouette Olivier , Champagne-Poirier Olivier , Loiola Francisco A. , Beaupré-Lavallée Alexandre , Paradis Philippe 
Published: July 2021

Cet article s’inscrit dans une étude sur les innovations pédagogiques qui découlent des transformations dans le monde de l’enseignement supérieur contemporain. En s’appuyant sur une étude de portée de 105 documents, cet article explore les fondements et les applications de quatre approches pédagogiques innovantes : les approches inductives, expérientielles, abductives et par projets transdisciplinaires. Prenant acte des points de convergence entre ces pédagogies, l’article propose une conceptualisation originale de ces interactions afin de faire progresser les réflexions quant à l’enseignement et à l’apprentissage.
La mise en oeuvre d’un projet d’université populaire et pluriépistémique au Brésil
Authors: Bicalho Gonçalves Gustavo B. , Borri-Anadon Corina 
Published: July 2021

Cet article présente les tensions liées à la mise en oeuvre de l’Université fédérale du Sud de Bahia (UFSB) au Brésil de 2014 à 2019. Il situe d’abord le contexte international et sociopolitique national dans lequel s’inscrit la création de cette institution. Par la suite, une présentation de l’UFSB est étayée selon deux orientations au centre de son plan de développement institutionnel initial : une université populaire et une université pluriépistémique. Une analyse de données secondaires ancrée dans la perspective du néo-institutionnalisme sociologique a permis de dégager les tensions relatives à ces deux orientations, à partir d’écrits portant spécifiquement sur l’expérience de mise en oeuvre de l’UFSB. La discussion aborde les liens entre ces tensions et les tendances assaillant l’université à l’échelle globale afin de contribuer à une meilleure compréhension des enjeux et défis auxquels est confrontée l’université du XXIe siècle.
The Role of Anti-Inflammatory Cytokines in Heart Failure
Authors: Pathimagaraj Rachel 
Published: July 2021

Coronary occlusion promotes a state of ischaemia that results in myocardial infarction; it is a major cause of mortality accounting for one hospital admission every three minutes. At the site of infarct, sterile inflammation is initiated due to pro-inflammatory secretions from cardiac and innate immune cells. The focus of this review is to explore the role of a newly discovered innate immune complex, the nod-like receptor family pyrin domain containing 3 inflammasome. This review discusses the potential of this immune complex in decreasing the proportion of functional myocardium during ischaemia and ischaemia-reperfusion injury. Due to the central role of this inflammasome in promoting cardiac dysfunction following an acute myocardial infarction, the risk of port-infarction heart failure increases. With an intention of highlighting the importance of improving current management of patients with acute myocardial infarction, this review addresses novel therapeutic agents that have demonstrated cardioprotective outcomes in recent studies. This follows discussion concerning the therapeutic potential of these agents, intending to form the basis of heart failure therapy.
Acque reflue e rischio ambientale: inquinamento fluviale nella Roma imperiale
Authors: Arena Gaetano 
Published: July 2021

The paper intends to examine a specific area of research concerning the pollution of large rivers – the Tiber above all but not exclusively – and the resulting contamination of water and air as well as the depletion of fish fauna and related food risks. The data on the damage to fluvial (but also lake and marine) habitats are not presented by the intellectuals of the Flavian-Trajan and Antonine ages (Pliny the Elder, Pliny the Younger, Galen) in an ‘environmentalist’ perspective stricto sensu, but each time presented in terms of moral condemnation, or of political propaganda aimed at seeking consensus or even in terms of risk to health and/or possible economic damage. In spite of this, from a legal point of view, appears undeniable a concern of the State to introduce measures aimed at limiting environmental damages as well as protecting and conserving natural resources, although certainly not systematic, but dictated by completely pragmatic needs and by occasional or emergency circumstances.
Comparative efficacy of different renin angiotensin system blockade therapies in patients with IgA nephropathy: a Bayesian network meta-analysis of 17 RCTs
Authors: Huo Zhihao , Ye Huizhen , Ye Peiyi , Xiao Guanqing , Zhang Zhe , Kong Yaozhong 
Published: July 2021

Background
IgA nephropathy (IgAN) is still one of the most prevalent forms of primary glomerulonephritis globally. However, no guidelines have clearly indicated which kinds of renin angiotensin system blockade therapies (ACEIs or ARBs or their combination) in patients with IgAN result in a greater reduction in proteinuria and a better preservation of kidney function. Thus, we conducted a Bayesian network analysis to evaluate the relative effects of these three therapy regimens in patients with IgAN.

Methods
The protocol was registered in PROSPERO with ID CRD42017073726. We comprehensively searched the PubMed, the Cochrane Library, Embase, China Biology Medicine disc, WanFang and CNKI databases for studies published since 1993 as well as some grey literature according to PICOS strategies. Pairwise meta-analysis and Bayesian network analysis were conducted to evaluate the effect of different regimens.

Results
Seventeen randomized controlled trials (RCTs) involving 1,006 patients were analyzed. Co-administration of ACEIs and ARBs had the highest probability (92%) of being the most effective therapy for reducing proteinuria and blood pressure, but ACEIs would be the most appropriate choice for protecting kidney function in IgAN.

Conclusion
The combination of ACEIs and ARBs seems to have a significantly better antiproteinuric effect and a greater reduction of blood pressure than ACEI or ARB monotherapy in IgAN. ACEIs appear to be a more renoprotective therapy regimen among three therapies.
Serum albumin and albuminuria predict the progression of chronic kidney disease in patients with newly diagnosed type 2 diabetes: a retrospective study
Authors: Li Yujiao , Ji Xiaobing , Ni Wenji , Luo Yong , Ding Bo , Ma Jianhua , Zhu Jian 
Published: July 2021

Background
Diabetes-related kidney disease is associated with end-stage renal disease and a high mortality rate. However, data on risk factors associated with kidney disease in patients with newly diagnosed type 2 diabetes mellitus (DM) remains insufficient. The aim of the present study was to identify the risk factors significantly associated with chronic kidney disease progression in patients with newly diagnosed type 2 DM.

Methods
We reviewed a total of 254 consecutive patients who were newly diagnosed with type 2 diabetes at Nanjing First Hospital from January to December 2014. They were observed for two years, and baseline and biochemical variables were used to identify significant predictors of kidney failure progression. Kidney failure progression was defined as a ≥ 30% increase in serum creatine level.

Results
The mean age of patients was 58.96 years, 37.4% were women, and 57.1% had hypertension. Kidney function progressed in 40 patients (15.75%). Multivariable logistic regression analyses showed that serum albumin (p = 0.015) and microalbuminuria (p < 0.001) were associated with kidney failure progression in patients with newly diagnosed type 2 DM. Those with lower estimated glomerular filtration rate (eGFR; 30–60 ml/min/1.73 m2) at baseline had lower serum albumin levels compared to those of patients with higher eGFR. The albuminuria levels were higher in patients with lower eGFR than in those with eGFR ≥ 90 ml/min/1.73 m2. Receiver operating characteristic curve analysis showed that the area under the curve was 0.754 (95% CI [0.670–0. 0.837]).

Conclusions
The overall rate of chronic kidney disease progression is relatively high, and low serum albumin and high albuminuria levels are associated with kidney failure progression in newly diagnosed diabetic patients.
Genetic Relationship between the Different Ethno-Linguistic Groups of Mezam and Momo Divisions of the North West Region of Cameroon
Authors: Fosah Ngum Precious , Cho-Ngwa Fidelis 
Published: July 2021

Aim: Although the many ethnolinguistic groups of the Mezam and Momo Divisions of the North West Region of Cameroon are historically known to be related, no genetic study has hider to be conducted to verify the claim. This study was therefore aimed at determining the genetic relationship between the different ethno linguistic groups of Mezam and Momo divisions of north west Cameroon using 6 Y-STR loci.
Materials and methods: Venous blood samples were collected from, at least 30 consented participants from each of 11 ethnolinguistic groups previously identified in the study area. Genomic DNA was isolated and six Y- Chromosome Short Tandem Repeats (Y-STRs): DYS388, DYS389I DYS390, DYS391, DYS392, and DYS393, were genotyped using standard techniques and the phylogenetic relationship between these groups established.
Results: Four loci (DYS3891, DYS390, DYS391, and DYS392) had an allele frequency of 1 in all 11 groups and a total of 4 haplotypes were obtained. Haplotype 11-13-21-11-9-10 corresponding to DYS388-DYS389I-DYS390-DYS392-DYS393-DYS391 was the most predominant in all populations.
Conclusion: It is concluded that, all 11 populations included in this study have a common genetic origin, the Bakaka population of Cameroon which correlates with their Bantoid linguistic relatedness.
Design of Grid-connected and Stand-alone Photovoltaic Systems for Residential Energy Usage: A Technical Analysis
Authors: Makinde Kehinde Adeleye , Adewuyi Oludamilare Bode , Amole Abraham Olatide , Adeaga Oyetunde Adeoye 
Published: July 2021

Towards realizing the United Nations sustainable development goals, access to clean, cheap and reliable energy, especially electricity, has been considered as one of the vital indices in any community. Hence, this paper presents the design analysis of both a grid-connected and an offgrid photovoltaic (PV) systems for household users in the highly residential city of Ogbomoso in Nigeria using PVGIS software. For the off-grid design, it is estimated that, given a total daily load of 9.57 kWh, a 3.5 kWp PV array size and a battery capacity of 86 kWh are enough to power the load with 5 days of autonomy and 70% depth of battery discharge. For the grid-connected PV system, the annual energy output for a building-integrated PV system is found to be around 4006 kWh; and a total of eight PV modules (each rated 250 Wp, 30.93 V) are stringed to arrive at the desired capacity of 2 kWp. In terms of performance, the performance ratio (PR) of a building integrated grid-tied PV system at the study location was found to be 71.2% while for a free-standing PV system, the PR was 75%.