bluuebunny/crossref_metadata_2025_split huggingface dataset:
The characterization of size-controlled nanocrystalline cellulose from soy hulls with ultrasonic assisted extraction
Authors: Yu Kejin , Yang Lina , Zhang Siyu , Zhang Ning , Liu He 
Published: December 2024

Abstract

Soybean is a crop of important economic significance and soy hull is the residual by-product of soybean processing industry. In this study, cellulose nanocrystals were extracted from soy hull using a combined acid hydrolysis-ultrasonic treatment process, and its structure, properties, and antimicrobial activity were investigated. Fourier-transform infrared spectroscopy revealed the presence of hydrogen and ester bonds in the soy hull nanocrystalline cellulose (SHNC), whereas scanning electron microscopy showed that the SHNC was globular or short-rod shaped with diameters in the range of 20–50 nm. The molecular weight of SHNC was 213,935 Da and the extraction yield was 11.42%. Meanwhile, SHNC also had high crystallinity (55.59%), thermal stability, transparency (80%), and UV resistance. Notably, SHNC exhibited an excellent bacteriostatic effect against Escherichia coli and Staphylococcus aureus, whose bacteriostatic percentage reached 69.33%. Meanwhile, this study provided a new idea for the high value utilization of waste soy hull.
Evaluating the Quality of Data: Case of Sarcasm Dataset
Authors: Bade Girma Yohannis , Kolesnikova Olga , Oropeza Jose Luis 
Published: December 2024

Abstract

The models of artificial intelligence (AI) rely on data as their primary fuel. Accurate and efficient AI models that generated by high-quality data may guarantee AI-safe use. Sentiment analysis (SA), one of the tasks in natural language processing (NLP), highly relies on sarcasm detection. Sarcasm’s cryptic character, however, makes it difficult and degrades its quality. Even though the problem was thoroughly investigated, it has been limited by the restrictions resulting from improper labeling and data not specifically gathered to identify sarcasm. This paper evaluates the quality of the sarcasm data by the performance of similarly parameterized models. To make an analysis, we compiled four distinct datasets—SARC, SemEval2022, NewsHeadline, and Multimodal. Undersampling and over-sampling techniques were used to balance the data size as well as class-label variations among the corpora. We perform extensive and fair evaluations on various models ranging from machine learning to transfer learning algorithms and employ TF-IDF vectorization and word embedding text representation techniques. Based on the experimental result, the NewsHeadline corpus exhibited greater quality, achieving a notable F1 score of 0.93 in RoBERTa’s model performance. We have created a new (Sarcasm-Quality) dataset combining the best-performing datasets based on the experimental analysis and made it available for public use.
Lobus Frontalis und ChatGPT – Chatbots als Lernassistenz für Studierende
Authors: Großauer Bettina , Hörmann Corinna , Sabitzer Barbara 
Published: December 2024

Die vorliegende Studie untersucht die Rolle von Chatbots als Lernassistenz für Studierende des gehobenen medizinisch-technischen Dienstes an Fachhochschulen in Österreich. Der Fokus liegt auf der aktuellen Nutzung und den zukünftigen Anforderungen dieser Technologie in der Hochschulbildung, insbesondere auf der Entwicklung und Implementierung von künstlicher Intelligenz (KI) als unterstützendes Werkzeug im Lernprozess. Die Ergebnisse einer Online-Umfrage mit 101 Studierenden zeigen, dass eine Mehrheit KI bereits nutzt und deren Potenzial erkennt. Insgesamt liefert die vorliegende Studie wichtige Einblicke, um ein tieferes Verständnis für die Wirksamkeit von KI als Lernassistenz zu erlangen und um maßgeschneiderte Anwendungen für die Hochschulbildung zu entwickeln.
Assessment of irrigation water management using FAO-CROPWAT 8 in the Paliganj distributary of the Sone irrigation scheme in Bihar: a case study
Authors: Praveen K. , Ray Rahul , Roy Lal Bahadur , Tiwari Deepak Kumar 
Published: December 2024

ABSTRACT
Around 15% of India's gross domestic product comes from agriculture, which is the foundation of the country's economy. India's economic development and efforts to combat poverty have already benefited greatly from its agricultural sector. Sustainable management of water resources can increase agricultural productivity. The study was performed in the Paliganj distributary, a part of the Sone canal system in south Bihar, India. The Paliganj distributary command area lies wholly in the Gangetic plain. The estimation of crop evapotranspiration was carried out using the Modified Penman–Monteith equation for the period 1980 to 2015. The crop coefficient of the crops has been estimated by using a single crop coefficient and a dual crop coefficient. The crop water requirement, irrigation water requirement, and irrigation scheduling of crops grown in the study area were determined using CROPWAT 8.0 software. The results conclude that the maximum, minimum, and average values of ET0 were found to be 7.65 mm/day, 1.31 mm/day, and 3.86 mm/day respectively. The crop water requirement and irrigation requirement of crops grown in Kharif, Rabi, hot weather, and annual seasons in the study area were lower by using dual crop coefficient.
Comparative analysis of water security in Kermanshah Province cities, Iran
Authors: Tavasol Nahid , Poursaeed Alireza , Eshraghi Samani Roya , Vahedi Marjan , Naseri Behrouz 
Published: December 2024

ABSTRACT

This study evaluates water security in the cities of Kermanshah Province, Iran, through the application of the water poverty index (WPI), incorporating five key components: resources, capacity, access, use, and environment. Data were sourced from official records and analyzed to generate WPI scores for each city. The results indicate that Kermanshah Province experiences medium to high levels of water poverty, with significant inter-city disparities. The WPI values ranged from 30.44 in Salas-e Babajani to 66.25 in Kermanshah, with an average provincial score of 43.84. Sahneh ranked highest in the ‘Resources’ component, due to its abundant groundwater and surface water, while Gilangharb and Salas-e Babajani reported the lowest scores, primarily due to unauthorized well extractions. In terms of access, Qasr-e Shirin achieved 99.92% coverage in safe water supply, whereas other cities, such as Javanrud and Salas-e Babajani, fell below 50%. Environmental conditions were generally favorable across the province, with the exception of Sarpol-e Zahab, where water quality was degraded by high pesticide and fertilizer use. These findings underscore the urgent need for tailored water management interventions to address the regional disparities in water security.
AÇÃO DO PERÓXIDO DE HIDROGÊNIO E PERÓXIDO DE CARBAMIDA NO CLAREAMENTO DENTAL: REVISÃO INTEGRATIVA
Authors: Dantas Anderson Tomaz , Oliveira Pedro Vitor dos Santos , Medeiros Fabianna da Conceição Dantas de 
Published: December 2024

Introdução: O clareamento de dentes escurecidos representa uma alternativa estética conservadora, simples e eficaz ao uniformizar a cor dos dentes. Dentre os agentes clareadores, destacam-se os géis de peróxido de hidrogênio e peróxido de carbamida como substâncias ativas com potencial clareador, com características e indicações específicas, seja de uso profissional ou por autoaplicação. Objetivo: Analisar a ação clareadora dos peróxidos de hidrogênio e carbamida no clareamento dental, mediante revisão integrativa da literatura. Metodologia: A busca dos estudos ocorreu nas bases de dados: LILACS, BBO e MEDLINE via portal da Biblioteca Virtual em Saúde (BVS), além da Scientific Eletronic Library Online (SciELO), Cochrane Library e PubMed usando combinações de descritores nas línguas portuguesa, inglesa e espanhola. A pergunta norteadora foi: “há diferença na eficiência clínica do clareamento realizado com peróxido de hidrogênio e de carbamida?”. Os critérios de inclusão consideraram ensaios clínicos publicados nos últimos cinco anos, redigidos em português, inglês ou espanhol, além de trabalhos disponíveis para download. A partir da leitura completa dos artigos, os dados extraídos foram agrupados em uma planilha. Resultados: No total, 17 artigos compuseram o corpo de análise da revisão, os quais integram os resultados clínicos de diferentes amostras variando a concentração e o tipo de substância clareadora, assim como protocolos de tratamento, diferentes métodos e tempos de avaliação da cor dos dentes clareados, assim como, os principais resultados. A combinação de protocolos clareadores ao associar etapas em consultório e autoaplicadas apresentaram os melhores resultados. Conclusões: A partir da análise dos artigos revisados, conclui-se que a simplificação dos protocolos com uso de peróxidos de baixas concentrações em períodos menores apresentam ação clareadora satisfatória no decorrer do tempo. Fatores como sensibilidade, tempo de trabalho, estabilidade na coloração dos dentes e maior satisfação do paciente podem orientar a escolha do protocolo clareador.
Palavras-Chave: Clareamento dental; Peróxido de hidrogênio; Peróxido de carbamida; Odontologia; Revisão.
Stem Cells Derived From Human Deciduous Exfoliated Teeth Ameliorate Adriamycin-Induced Nephropathy In Rats By Modulating The Th17/Treg Balance
Authors: Dai Yuyang , Tang Borui , Zhao Xiuli 
Published: December 2024

Background:
Idiopathic Nephrotic Syndrome (INS) is a common kidney disease in
children, and the main clinical manifestations are hypoproteinaemia, proteinuria, hyperlipidaemia,
and oedema. Mesenchymal Stem Cells (MSCs) are involved in tissue repair, protection against fibrosis,
and immune modulation but have rarely been studied in INS.

Objective:
This study aimed to explore the therapeutic potential of stem cells derived from human
exfoliated deciduous teeth (SHEDs) in INS using an adriamycin-induced nephropathy (AN) rat
model.

Methods:
AN was induced in Sprague‒Dawley rats, and SHEDs were transplanted via the tail
vein in single (SHED-s) and multidose (SHED-m) regimens. Cell migration assays were used to
track the SHED distribution. Weight, urine protein, and serum biochemical assays were also performed.
HE and Masson staining were used to observe glomerular and tubular damage, as well as
the degree of fibrosis. Immunohistochemistry was used to label T lymphocytes and podocytes,
and structural changes in podocytes were observed by electron microscopy. ELISA was used to
measure the levels of inflammatory factors. Flow cytometry was used to analyse the balance of
Th17 cells and Tregs. The mRNA expression of Th17- and Treg-associated cytokines and specific
transcription factors was examined by RT‒PCR.

Results:
SHEDs directly migrated to damaged tissues, suggesting a targeted therapeutic effect.
SHED transplantation significantly reduced proteinuria and reversed biochemical abnormalities in
rats with AN. Both single and multidose SHED treatments could inhibit glomerular and tubular damage
and delay the progression of fibrosis caused by adriamycin. SHEDs exerted a protective effect
on podocytes. Additionally, this treatment inhibited inflammatory responses and corrected immune
imbalances, as evidenced by decreased T lymphocyte infiltration, reduced serum levels of
IL-6, TNF-a, and IL-1β, and modulation of the Th17/Treg balance.

Conclusion:
In the AN rat model, SHED partly suppressed the development of inflammation and
alleviated kidney injury, and immune regulation may be the underlying mechanism.
In vitro Anti-biofilm and Anti-adhesion Effects of Lactic Acid Bacteria- derived Biosurfactants against Streptococcus mutans
Authors: Pourhajibagher Maryam , Bahador Abbas 
Published: December 2024

Introduction:
Biosurfactants are naturally occurring compounds with various ap-plications, biodegradable, non-toxic, and effective in different conditions. This study fo-cuses on the extraction and evaluation of biosurfactants produced by five strains of lactic acid bacteria [LAB] for their potential to inhibit biofilm formation and adhesion by Strep-tococcus mutans.

Methods:
The strains of LAB-producing biosurfactants such as Lactobacillus salivarius, L. acidophilus, L. plantarum, L. casei, and L. rhamnosus were confirmed by the hemolysis test. The presence of biosurfactants derived from LAB strains and their molecular compo-sition were confirmed, and their cellular toxicity, minimum inhibitory concentration [MIC], and minimum bactericidal concentration [MBC] were investigated. Ultimately, the anti-biofilm and anti-adhesive activities of LAB-derived biosurfactants against S. mutans were determined. Eventually, the effect of biosurfactants on the changes in gene expression associated with biofilm formation of S. mutans was assessed.
All the LAB strains used in this study were biosurfactant producers. The LAB-derived bi-osurfactants exhibited no cytotoxicity towards the human gingival fibroblast [HGF] cell line. According to the results, the lowest and highest MIC values were observed in the biosurfactants derived from L. rhamnosus and L. plantarum at 0.78 mg/mL and 6.25 mg/mL, respectively. The MBC values for the biosurfactants derived from L. rhamnosus, L. casei, L. salivarius, L. acidophilus, and L. plantarum were 3.12, 3.12, 6.25, 12.5, and 12.5 mg/mL, respectively. The LAB-derived biosurfactants at MBC concentrations exhib-ited significant inhibitory effects on biofilm formation and adhesion of S. mutans [P<0.05]. The highest anti-biofilm and anti-adhesion activities were attributed to the biosurfactants derived from L. plantarum, which were not significantly different from the 0.2% chlorhex-idine as a positive control group [P>0.05]. Moreover, all biosurfactants could significantly decrease the gene expression level of gtfB [P>0.05].

Results:
The study found that LAB-derived biosurfactants exhibit significant anti-adhesion and anti-biofilm activities against S. mutans without any observed cellular toxicity towards HGF cells.

Conclusion:
These promising bioactive compounds can be utilized as natural antimicrobial agents and biofilm inhibitors to prevent microbial biofilm formation and adhesion in vari-ous dental applications, offering a safe and effective alternative for controlling dental bio-films and improving oral health outcomes.
Enhancing Acyclovir Permeability Using SLS Crosslinked β-Cyclodextrin Nanoparticles
Authors: Gauniya Priyanka , Radheshyam  , Dobriyal Sukirti , Pandey Mukesh , Semalty Ajay , Semalty Mona 
Published: December 2024

Introduction/Objective:
Acyclovir, a BCS class III drug (that has high solubility and low
permeability) is an antiviral drug used for the treatment of herpes simplex and varicose zoster. To
enhance acyclovir's permeability across the intestinal membrane and to improve its bioavailability
the β-cyclodextrin (β-CD) nanoparticles of acyclovir were prepared with sodium lauryl sulfate
(SLS) as a crosslinking agent.

Methods:
A phase solubility study was performed with varying ratios of acyclovir to β-CD. Three
formulations of acyclovir-loaded β-CD nanoparticles were prepared with drug-β-CD ratios of 1:1,
1:2, and 1:4. The prepared nanoparticle formulations were characterized for FTIR, dynamic light
scattering (particle size, polydispersity index, zeta potential) and in vitro permeability studies.

Results:
Phase solubility study resulted in an "AL type" curve with an association constant (Kc) of
12 M-1 which suggested the formation of a strong complex between acyclovir and β-CD, leading to
enhanced solubility of acyclovir with increasing concentrations of β-CD. The FTIR spectrum confirmed
the compatibility of acyclovir, β-CD, and SLS in the formulations. Dynamic light scattering
analysis demonstrated particle sizes ranging from 152.92 nm to 335.7 nm, with the smallest particles
in the 1:4 ratio formulation (152.92 nm), potentially due to higher drug encapsulation. Zeta potential
measurements reflected formation of stable nanoparticle suspensions, with the formulation
exhibiting a zeta potential of -45.4 mV showcasing optimal stability. In vitro permeation studies revealed
that the 1:4 ratio formulation exhibited the highest permeability (84.24 ±1.94 % at the end of
150 min) through the eggshell membrane, implying efficient drug release. This increase in permeability
corroborated with its smallest particle size.

Conclusion:
The study highlights the potential of β-CD nanoparticles (with best performance
shown by drug-to-β-CD ratio 1:4) in augmenting acyclovir's delivery, suggesting a promising avenue
for improving the drug delivery in viral infections.
Continuous Improvement of Chronic Tinnitus Through a 9-Month Smartphone-Based Cognitive Behavioral Therapy: Randomized Controlled Trial
Authors: Walter Uso , Pennig Stefan , Bleckmann Lothar , Röschmann-Doose Kristina , Wittig Thomas , Thomsen Jörn , Schlee Winfried 
Published: December 2024

Background
Tinnitus is the perception of sound without an external auditive stimulus and can be a severe burden for affected patients. Medical guidelines recommend cognitive behavioral therapy (CBT) for tinnitus treatment, which effectively improves tinnitus-related distress and anxiety.

Objective
This study investigates the outcome of a 9-month smartphone-based CBT for patients with tinnitus.

Methods
The randomized controlled clinical trial in this study investigates the efficacy of a smartphone-based CBT for 187 patients with chronic tinnitus over a 9-month treatment period. In the initial 3 months, a waiting list design was applied, and in the subsequent study phase, the data of both treatment groups were collectively analyzed. The scores on the Tinnitus Questionnaire (TQ); 9-item Patient Health Questionnaire (PHQ-9); 9-item Self-Efficacy, Optimism, Pessimism (SWOP-K9) questionnaire; and 20-item Perceived Stress Questionnaire (PSQ-20) were assessed as endpoints after 3 and 9 months of treatment.

Results
We observed a statistically significant reduction in the tinnitus burden in patients who received the smartphone-based CBT intervention. Although no changes were observed initially in the TQ sum scores in the waiting control group (baseline mean, 37.8, SD 4.7; 3 months mean 37.5, SD 4.8; analysis of covariance [ANCOVA] P=.52), the scores significantly decreased once the app-based CBT had commenced. Data pooled from both groups revealed significant reduction in the TQ sum score by 12.49 (SD 1.44) (ANCOVA, P<.001) and 18.48 (SD 1.85) (ANCOVA, P<.001) points after 3 and 9 months, respectively, which was also clinically important. The calculated Cohen d was 1.38. Similarly, the scores on PSQ-20 (–9.14 points; ANCOVA, P<.001), PHQ-9 (–2.47 points; ANCOVA, P<.001), and SWOP-K9 (0.17 points; ANCOVA, P<.001) were significantly improved at the end of the therapy, with corresponding intermediate effect sizes after 9 months.

Conclusions
The data in our study provide evidence of statistically significant, clinically relevant, and continuous benefits of an app-based CBT intervention in patients with chronic tinnitus.

Trial Registration
Deutsches Register Klinischer Studien DRKS00022973; https://drks.de/search/de/trial/DRKS00022973
Implementação de Técnica de Identificação de Alarmes de Braços Ferramentas em Centros de Usinagem de Alta Velocidade em Indústria Metal Mecânica: aplicação da Engenharia de Dados em um estudo de caso
Authors: Moura Delmo Alves de , Peixoto Diego 
Published: December 2024

Iniciativas da engenharia de manutenção, com foco em manutenções preditivas ajudam a estimar quando ocorrerá a falha em equipamentos. Essa previsão nos permite planejar a manutenção com antecedência, reduzir custo, eliminar tempos de paradas não planejados e maximizar a vida útil do equipamento. O uso das tecnologias da Indústria 4.0 (I4.0) e as técnicas da ciência dos dados, permitiram, à engenharia de manutenção, o desenvolvimento de algoritmos inteligentes, que contribuem para a análise, em tempo real, de uma quantidade enorme de dados, transformando-os em informações, para tomada de decisão numa fábrica. Neste trabalho foi implantado um sistema de coleta e análise de dados reais, para identificar os alarmes e a saúde de um sistema de troca de ferramentas de alta velocidade de máquinas de usinagem, de uma linha de cilindros de combustão, de uma indústria metal mecânica. O objetivo do artigo foi estudar a coleta de dados em tempo real de máquinas de usinagem, de uma linha de cilindros de combustão de uma indústria metal mecânica, analisá-los, através da ciência dos dados e transformá-los em informações para tomada de decisão, visando redução de custos operacionais, aumentar vida útil de equipamentos e reduzir parada de máquinas na fábrica.
quinas na fábrica.
dimensões poética e ensaística na obra recente de Tamara Kamenszain
Authors: Fontes Mariana 
Published: December 2024

Este trabalho procurará discutir as dimensões ensaística e poética da produção recente de Tamara Kamenzain, a partir principalmente de suas duas últimas publicações: Libros chiquitos (2020) e Chicas en tiempos suspendidos (2021). A obra poética de Kamenszain, sobretudo a mais recente, coloca em cena a crítica à obra de outros autores e à sua própria obra, além do o ensaio de termos chave em verso. Por outro lado, seus ensaios são marcados por elementos como refrões e imagens poéticas. Em comum a essas duas vias, está a leitura enquanto origem da escrita, seja ela ensaística ou poética. Sendo assim, pretendo pensar como esses traços dialogam entre si e ganham materialidade.
Orlando Senna
Authors: Ulhôa Marco Túlio 
Published: December 2024

Nesta conversa com Orlando Senna, o cineasta descreve alguns dos principais momentos de sua carreira, cujo começo se dá na Bahia no início dos anos 1960, passando por sua participação diretamente do surgimento do Cinema Novo, até o presente. Das suas experiências como realizador, destaca a sua contribuição para o meio cinematográfico tanto no Brasil quanto na América Latina, ao relatar a sua experiência como jornalista e como esta também foi responsável por conectá-lo a alguns dos eventos mais importantes da história do Chile e de Cuba. Entre estes eventos, destaca a sua participação na criação da Escuela Internacional de Cine y Televisión (EICTV), de San Antonio de Los Baños (Cuba) e sua relação com o cineasta cubano, Santiago Álvarez.
LAMA MASA INKUBASI PUPUK ORGANIK DAN ANORGANIK UNTUK PERBAIKAN SIFAT FISIK TANAH PADA PERSIAPAN MEDIA TANAM TANAMAN BAWANG MERAH
Authors: Mulyani Sri , Zahrah Siti , Salman Salmita , Fathurrahman Fathurrahman , Ernita Ernita 
Published: December 2024

Penelitian ini bertujuan untuk mengetahui lama masa inkubasi berbagai pupuk organik dan anorganik terhadap sifat fisika tanah untuk media tanam bawang merah. Penelitian ini telah dilaksanakan di Desa Kualu, Kecamatan Tambang, Kabupaten Kampar selama 5 bulan dari bulan Agustus 2022 sampai dengan bulan Desember 2022. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) tunggal terdiri dari 13 perlakuan dengan 3 ulangan sehingga diperoleh 39 satuan percobaan. Data masing-masing perlakuan hasil pengamatan dianalisis statistik. Jika F hitung lebih besar daripada F tabel dilanjutkan dengan melakukan uji lanjut DMRT dengan taraf 5%. Parameter pengamatan sifat fisika tanah yaitu suhu tanah, bulk density tanah, partikel density, porositas tanah, dan warna tanah. Berdasarkan hasil penelitian rata-rata suhu tanah pada pukul 07.00-08.00 WIB, pukul 13.00-14.00 WIB dan pukul 17.00-18.00 WIB dengan kondisi cuaca cerah dan panas suhu tanah hariannya 36,50C. Sedangkan rata-rata suhu tanah pada pukul 07.00-08.00 WIB, pukul 13.00-14.00 WIB dan pukul 17.00-18.00 WIB dengan kondisi cuaca malam hujan, cuaca siang cerah dan cuaca sore gerimis suhu tanah hariannya 34,20C lebih tinggi daripada suhu tanah untuk pertumbuhan tanaman bawang merah. Warna tanah yang dihasilkan pada perlakuan lama waktu inkubasi pupuk organik dan perbandingan rekomendasi pupuk anorganik yaitu 2,5Y 3/1, 7,5YR 2,5/1, 7,5YR 3/1, 10YR 3/1, sedangkan pada perlakuan kontrol 5YR 6/1. Perlakuan lama waktu inkubasi pupuk organik dan perbandingan rekomendasi pupuk anorganik untuk media tanam tanaman bawang merah berpengaruh nyata terhadap bulk density dan porositas tanah. Perlakuan yang terbaik terdapat pada perlakuan lama waktu inkubasi 1 bulan+pupuk kandang ayam+pemupukan petani (B10).