bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH KEBUGARAN JASMANI TERHADAP LAMA PERSALINAN KALA I DAN II PERSALINAN PADA IBU PRIMIGRAVIDADI BPM KOTA MEDAN TAHUN 2015
Authors: Bangun Sartini , Hutabarat Julietta , Gultom Lusiana 
Published: April 2021

Physical fitness of pregnant women who are exercise actively have a better vascularization than those who passively. Physical exercise is a major factor in improving physical fitness, flow capacity of the heart, and obtain a high oxygen during labor (Varney and others 2007, Hamilton 1995, Bobak and others 2005), therefore team authors were interested in researching about physical fitness effectiveness for a long period time in first and second stage of labor in primigravida. Method : this type of research is a Quasi Experiment and Non-Equivalent Control Group, population total are 40 respondents (3rd trimester primigravida) measuring the level of physical fitness (VO max), period of 1st
stage, 2nd stage and total period time of labor. Data analysis using T test. Result : from 20
respondents of experimental group and 20 groups non-experiment obtained homogeneous data regarding physical fitness and psychological condition. The average time period of 1st stage in experimental group are 387,75 minutes (Sd. 43,54), the average time period of 2nd stage are 27,75 minutes (Sd. 9,66). Total period of labor average 334,50 minutes (Sd. 44,35), while in non- experimental group the period time of 1st stage average 448,75 minutes (Sd. 41,64), 2nd stage 40,00 minutes (Sd. 8,27) and the average of total period are 478,75 minutes (Sd. 82,64). T test in the experimental group and non-experimental group obtained homogeneous data because p value (0,794)
> ? (0,005). Period time of 2nd stage p value (0,602) > ? (0,005). The period time of labor not normal, analysist using Mann Whitney test obtained p value (0,00) < ? (0,005). Concluded that there is the influence of maternal physical fitness with period of 1st and 2nd stage of labor and suggested for all
pregnant women improving physical fitness with physical exercise using a bicycle ergometer.
EFEKTIVITAS METODE CERAMAH DAN DISKUSI KELOMPOK TERHADAP PENGETAHUAN DAN SIKAP TENTANG KESEHATAN REPRODUKSI PADA REMAJA DI YAYASAN PENDIDIKAN HARAPAN MEKAR MEDAN
Authors: Tarigan Amira Permata Sari 
Published: April 2021

The problems of the adolecent’s reproductive health show an escalation year by year. Based on the survey carried out in Yayasan Pendidikan Harapan Mekar Medan in February of 2010, found 4 (four) cases of Unwanted Pregnancy in 2009-2010 and there were 8 (eight) cases of unwanted pregnancy within 5(five) last year (2005 to 2010). One of the factors assumed to be causing of the problem was lack of adolescent’s knowledge about reproductive health. This study aimed to analyze the effectiveness of lecturing and group discussion methods on adolecent’s knowledge and attitudes regarding to reproductive health in Yayasan Pendidikan Harapan Mekar Medan in 2010. This type of research was the true experimental pretest-posttest control group design. Population were students of the Yayasan Pendidikan Harapan Mekar Medan. Sample of 90 people who were divided into three groups: experimental group I were treated with lecturing method as many as 30 people, experimental group II were treated with group discussions method as many as 30 people and a control group without treatment as many as 30 people. The results showed that the highest mean difference of knowledge score (6,30) occurred in the group treated through extension with group discussion methods with standart deviation of 2,96, while the mean difference of the score in the group treated through extension with lecturing methods was 4,03 with standart deviation of 2,14. In terms of the variable of attitude, the treatment of extension with group discussion methods showed a higher score improvement (13,60) with standart deviation of 7,77 compared to the score improvement of the group treated through extension with lecturing methods which reached 7,87 with standard deviation of 5,73. The result of ANOVA test and Tamhane’s T2 test further showed that the group discussion methods was effective in improving the knowledge and attitude about reproductive health among adolescents in Yayasan Pendidikan Harapan Mekar Medan.The health promotor is suggested to applied group discussion method when carrying out the extension on health in order to make the result desired can be optimally achieved.
PENGARUH STATUS GIZI DAN STIMULASI IBU TERHADAP TUMBUH KEMBANG BALITA DI PAUD AL IKHLAS KELURAHAN PADANG BULAN KECAMATAN MEDAN BARU KOTA MEDAN
Authors: Mahyani Eva , Meliasari Dewi , Wildan Wildan 
Published: April 2021

Upaya pengembangan kualitas SDM dengan mengoptimalkan potensi tumbuh kembang anak.Pertumbuhan dan perkembangan anak merupakan hasil interaksi antara faktor genetik-herediter- konstitusi dengan faktor lingkungan. Peran orang tua dalam mendukung pertumbuhan dan perkembangan anak sangat penting, dimana orang tua bisa menyediakan sarana untuk tumbuh dan berkembang dengan baik dan sempurna. Pertumbuhan dan perkembangan balita dapat tumbuh secara optimal bila orang tua dapat mengasuh balitanya dengan benar, pemeliharaan kesehatan yang memadai, memberikan gizi yang adekuat, kondisi lingkungan yang bersih dan merangsang atau menstimulasi yang terarah kepada balitanya sesuai dengan usia dalam semua aspek perkembangan baik motorik kasar, motorik halus, bahasa dan personal social. Tujuan penelitian ini adalah untuk melihat Pengaruh Status Gizi Dan Stimulasi Balita Terhadap Tumbuh Kembang Balita di Paud Al Ikhlas Kelurahan Padang Bulan Kecamatan Medan Baru Kota Medan Tahun 2016. Penelitian ini merupakan penelitian survei dengan pendekatan cross sectional. Penelitian ini dilalakukan di PAUD Al Ikhlas Kelurahan Padang Bulan Kecamatan Medan Baru Kota Medan.dengan sampel berjumlah 69orang yang diambil dengan teknik simple random sampling.Analisis data menggunakan uji regresi logistic berganda.Berdasarkan analisis bivariat didapat hasil ada hubungan antara status gizi dengan tumbuh kembang balita dengan nilai p<0,001, ada hubungan antara stimulasi ibu dengan tumbuh kembang balita dengan nilai p<0,001, dan dari analisis multivariat didapatkan hasil status gizi dan stimulasi ibu berpengaruh terhadap tumbuh kembang balita dengan nilai Exp(B) =38,650 untuk status gizi dan Exp(B)=59,848 untuk stimulasi.Saran kepada orang tua untuk menjaga tumbuh kembang anak, memberikan stimulas sesuai tumbuh kembang anak dan meningkatkan peran ibu untuk mencari informasi tentang perkembangan anak.
GAMBARAN EFEKTIFITAS PERAWATAN LUKA DIABETIK MENGGUNAKAN MODERN DRESSING DAN KONVESIONAL DI ASRI WOUND CARE CENTER DAN R.S.U MARTHA FRISKA MEDAN TAHUN 2015
Authors: Nurhaida Nurhaida 
Published: April 2021

Luka diabetik adalah kondisi medis yang ditandai dengan luka cekung yang lama, tidak menyembuh, dengan pembengkakan dan berbatas tegas. Pada pasien diabetes cendrung terjadi penyakit arteri perifer, suatu kondisi dimana terjadi penyumbatan pembuluh darah ditungkai dan neuropati perifer, suatu kondisi dimana terjadi kerusakan saraf-saraf pada tungkai akibat kadar gula darah yang tinggi. Tujuan dari penelitian ini adalah Untuk Mengetahui Bagaimana Gambaran Efektifitas Perawatan Luka Diabetik Menggunakan Modern Dressing dan Konvesional di Asri Wound Care Center Medan dan R.S.U. Martha Friska Medan. Populasi dalam penelitian ini berjumlah 4 responden, 2 responden sebagai kelompok intervensi dan 2 responden sebagai kelompok kontrol. Sampel dalam penelitian ini menggunakan Total Sampling. Dari hasil penelitian Dari data demografi responden berdasarkan jenis kelamin ditemukan mayoritas adalah laki-laki berjumlah 3 responden (75%) dan minoritas adalah perempuan berjumlah 1 responden (25%). Berdasarkan umur dan frekuensi terbanyak ada pada rentang umur responden 41-60 tahun yang berjumlah 3 responden (75%) dari 4 responden penelitian. Pada kelompok intervensi didapat nilai frekuensi 2 responden (100%) sembuh. Sedangkan pada kelompok Kontrol didapatkan hasil frekuensi 1 responden (50%) tidak sembuh. Dengan melihat hasil dari penelitian ini,peneliti merekomendasikan kepada tim kesehatan yang melakukan perawatan khususnya di tempat pelayanaan kesehatan harus lebih memahami dan mengetahui konsep perawatan luka dengan menggunakan terapi Modern Dressig tepat guna. Hal ini dikarenakan Modern Dressing sangat efektif untuk mempercepat fase penyembuhan luka.
RELATIONSHIP REGULATION OF F ARDHU PRAYER WITH STRESS LEVEL OF SEMESTER 8 STUDENTS FACULTY OF MEDICINE MUHAMMADIYAH UNIVERSITY PURWOKERTO
Authors: Azizi Rifaqul , Kusumawinakhyu Titik , Finurina Irma 
Published: April 2021

Fardhu prayer is a compulsory activity that can create peace of mind for those who run it. For medical students in semester 8 of FK UMP who are experiencing many exams and personal problems, prayer can help calm and relieve stress. This study aims to determine the relationship between the regularity of fardhu prayer and stress levels in 8th-semester students of the Faculty of Medicine, Muhammadiyah University of Purwokerto. Methods use a correlational analysis research design with a cross-sectional approach. The study was conducted on an entire population of 48 students of the Faculty of Medicine, Muhammadiyah University of Purwokerto. Stress level data were obtained using the DASS test questionnaire, and prayer regularity data were obtained from the fardhu prayer regularity questionnaire. Data analysis with Pearson parametric correlation test. Results show the highest level of stress in students who experienced mild stress, and the results of the regularity of student prayers were found that many students regularly prayed. Based on the Pearson correlation test results, the value of p = 0.0 10 was obtained. There is a significant relationship between the regularity of fardhu prayer and the stress of the 8th-semester students of the Faculty of Medicine, Muhammadiyah University of Purwokerto, class of 2013.
PERBANDINGAN PRAKTIK PEMBIAYAAN TABUNGAN SAFARI KOSPIN JASA SYARIAH BANJARAN TEGAL DENGAN FATWA DSN MUI NO. 02 TAHUN 2000
Authors: Putri Nurul Wulandari , Febriani Dhiya Faras 
Published: April 2021

Pada zaman dimana ekonomi yang sedang tidak menentu, perlu sekiranya setiap individu memiliki cadangan dana. Cadangan dana tersebut yang sangat mudah dilakukan oleh masyarakat dapat berbentuk tabungan. Dalam hal Kospin Jasa Syariah Capem Banjaran hadir untuk memberikan produk yang dibutukan oleh masyarakat salah satunya Tabungan Safari yang merupakan tabungan berjangka dengan wisata gratis. Tujuan dari penelitian ini yaiitu untuk mengetahui tingkat kepatuhan pada produk Tabungan Safari Kospin Jasa Syariah Capem Banjaran terhadap Fatwa DSN MUI No. 02/DSN-MUI/IV/2000 tentang Tabunga. Penelitian ini menggunakan metode kualitatif deskriptif. Hasil penelitian ini menunjukkan bahwa praktik pembiayaan Tabungan Safari di Kospin Jasa Syariah Capem Banjaran masih ada beberapa yang tidak sesuai dengan Fatwa DSN MUI. Perbandingan praktik dalam pembiayaan Tabungan Safari telah sesuai dengan Fatwa DSN MUI No.02/DSN-MUI/IV/2000 tentang Tabungan, diantaranya nasabah bertindak sebagai shahibul mal dan bank sebagai mudharib, modal yang diiyatakan Kospin Jasa Syariah harus menjelaskan jumlahnya dan dalam bentuk tunai bukan piutang, pembagian keuntungan didapatkan harus dinyatakan dalam bentuk nisbah. Tetapi ada juga beberapa praktik yang tidak sesuai dengan Fatwa DSN MUI seperti bank dapat melakukan berbagai macam usaha tetapi praktiknya Kospin Jasa Syariah menggunakan dana tersebut sebagai dana outstanding, yang mana seharusnya Kospin Jasa Syariah dapat.Kata Kunci: Tabungan Safari, Kepatuhan Syariah, DSN MUI
Comparison of morphine, dexmedetomidine and dexamethasone as an adjuvant to ropivacaine in ultrasound-guided supraclavicular brachial plexus block for postoperative analgesia—a randomized controlled trial
Authors: Venkatraman Rajagopalan , Pushparani Anand , Karthik Krishnamoorthy , Nandhini Prabuvel 
Published: April 2021

Background and Aims:
An ideal adjuvant to local anesthetic in a nerve block should prolong the duration of analgesia, and hasten the onset of sensory and motor blockade without significant adverse effects. The aim of this study was to compare morphine, dexmedetomidine, and dexamethasone as an additive to ropivacaine in ultrasound-guided supraclavicular brachial plexus block (SBPB) for postoperative analgesia.

Material and Methods:
In this randomized, double-blinded study, 150 patients undergoing upper extremity surgery were randomly divided into three groups: group A (morphine 5 mg), group B (dexmedetomidine 50 μg), and group C (dexamethasone 8 mg). The additives were added to 30 ml of 0.5% ropivacaine solution and administered in SBPB. The duration of postoperative analgesia, onset of sensory and motor blockade, sedation, and adverse effects were observed. The pain was assessed by visual analog scale (VAS) and sedation by Ramsay sedation score. The duration of postoperative analgesia was taken as time consumed from block completion to administration of rescue analgesia (VAS >3).

Results:
The demographic profile was similar in both groups. The duration of analgesia was significantly longer in dexamethasone (867.2 ± 217.6 min) than morphine (739. 2 ± 162.5 min) and dexmedetomidine (654.2 ± 179.9 min) (P < 0.001). The onset of sensory and motor blockade was quicker with dexmedetomidine than dexamethasone and morphine. Three cases of block failure were reported with morphine. No major adverse effects were reported.

Conclusion:
Dexamethasone is an ideal adjuvant to ropivacaine in brachial plexus block to prolong postoperative analgesia and devoid of adverse effects. Dexmedetomidine has a quicker onset of sensory and motor blockade.
Clinical Appraisal of Corpora Cavernosa Injuries (Penile Fracture)
Authors: Elkhafifi Muftah Hamad , Alaorfi Wael E. Y. 
Published: April 2021

Background and Aim:
Penile fracture is a relatively rare urological emergency. The aim of this study was to review the experience with 69 consecutive cases in Benghazi, Libya.

Patients and Methods:
Records of 69 penile fracture cases who presented between January 1997 and December 2018 to Hawari Center for Urology, Benghazi, Libya were retrospectively reviewed. Penile fracture diagnosis was based on classic history and typical physical signs. Surgical exploration was performed for all patients under spinal anesthesia.

Results:
The most common mechanism of penile fracture was self-inflicted forceful bending (manipulation) of erected penis which account for 39 (56.5%) patients, followed by vigorous sexual intercourse in 19 (27.5%) patients, masturbation in five (7.2%) patients, rolling over an erect penis in bed in five (7.2%) patients, and slipping in WC in one (1.5%) patient. Clinical features at presentation include intense pain in 97%, sudden audible popping sound in 87%, rapid de tumescence in 94.2%, followed by development of swelling and ecchymosis in all patients (100%). All patients were treated surgically and no intraoperative or immediate postoperative complications were encountered. During the follow-up period, all patients had normal urinary steam and normal sexual function was experienced by 97.1% of the patients. Five patients (7.2%) had long-term complications: penile hypoesthesia (one patient), painful erection (one patient), penile curvature of <15o on erection (one patient), and mild erectile dysfunction (two patients). Most patients were discharged home on postoperative day 1.

Conclusion:
Penile fracture occurred mainly due to forceful sexual manipulation of erected penis, and diagnosis can be made clinically. Immediate surgical repair is the only option to avoid complications.
PENERAPAN BIMBINGAN BERKELANJUTAN UNTUK MENINGKATKAN KOMPETENSI GURU DALAM MENYUSUN RENCANA PELAKSANAAN PEMBELAJARAN (RPP) BERKARAKTER DI SMP NEGERI 1 TAMBELANG, KABUPATEN BEKASI TAHUN PELAJARAN 2019-2020
Authors: SITI FATONAH SITI FATONANH 
Published: April 2021

Penelitian ini dilakukan dengan tujuan: (1) memperoleh gambaran penerapan bimbingan berkelanjutan untuk meningkatkan kompetensi guru menyusun RPP berkarakter; (2) melihat partisipasi dan aktivitas guru dalam mengikuti kegiatan bimbingan berkelanjutan untuk meningkatkan kompetensi guru menyusun RPP berkarakter; (3) mengetahui peningkatan kompetensi guru menyusun RPP berkarakter melalui bimbingan berkelanjutan; (4) melihat respon yang muncul dari guru dalam kegiatan bimbingan berkelanjutan untuk meningkatkan kompetensi guru menyusun RPP berkarakter. Penelitian ini menggunakan metode Penelitian Tindakan Sekolah (PTS). PTS dapat diartikan sebagai penelitian tindakan / action research yang dilakukan dengan tujuan untuk memperbaiki kwalitas proses dan prestasi belajar siswa. Subjek dalam penelitian ini adalah guru di SMP Negeri 1 Tambelang, Kabupaten Bekasi, Jawa Barat, tahun pelajaran 2019 – 2020, semester ganjil. Berjumlah 30 orang guru , dengan perincian jumlah guru laki-laki 13 orang, guru perempuan berjumlah 17 orang. Instrumen penelitian yang dipergunakan dalam penelitian ini meliputi: (1) wawancara; (2) observasi ; (3) diskusi. Hasil dari penelitian ini yaitu sebagai berikut : (1) Partisipasi dan aktivitas guru dalam mengikuti kegiatan bimbingan berkelanjutan untuk meningkatkan kompetensi guru menyusun RPP berkarakter cukup tinggi dan bersemangat; (2) Melihat respon yang muncul dari guru dalam kegiatan bimbingan berkelanjutan untuk meningkatkan kompetensi guru menyusun RPP berkarakter; (3) Bimbingan berkelanjutan dapat meningkatkan motivasi guru dalam menyusun RPP dengan lengkap. Guru menunjukkan keseriusan dalam memahami dan menyusun RPP apalagi setelah mendapatkan bimbingan pengembangan/penyusunan RPP dari peneliti. Informasi ini peneliti peroleh dari hasil pengamatan pada saat mengadakan wawancara dan bimbingan pengembangan/penyusunan RPP kepada para guru; (3) Bimbingan berkelanjutan dapat meningkatkan kompetensi guru dalam menyusun RPP. Hal itu dapat dibuktikan dari hasil observasi /pengamatan yang memperlihatkan bahwa terjadi peningkatan kompetensi guru dalam menyusun RPP dari siklus ke siklus. Pada siklus 1 nilai rata-rata komponen RPP 79% dan pada siklus 2 = 93%. Jadi, terjadi peningkatan 14% dari siklus 1
ANALISIS KINERJA KEUANGAN DENGAN PENDEKATAN METODE ECONOMIC VALUE ADDED (EVA) PADA PT. BLUE BIRD Tbk PERIODE 2014-2018
Authors: Zakaria Hamzah Zeze , Awaliyah Sarah 
Published: April 2021

Penelitian ini bertujuan untuk mengetahui kinerja keuangan PT. Blue Bird Tbk yang diteliti berdasarkan analisis dengan menggunakan metode Economic Value Added (EVA) periode 2014 – 2018, jenis yang digunakan dalam penelitian ini adalah kuantitatif. Populasi penelitian yang juga merupakan sampel penelitian ialah laporan keuangan lima tahun terakhir (2014-2018). Pengumpulan data di lakukan dengan mengambil dokumentasi dari website resmi dan selanjutnya dianalisis dengan menggunakan metode EVA yang terdiri dari analisis NOPAT, Invested Capital, WACC, Capital Charges. Hasil penelitian menunjukkan bahwa Economic Value Added (EVA) pada PT. Blue Bird Tbk periode 2014-2018 mendapatkan nilai EVA < 0 artinya perusahaan tidak dapat menciptakan nilai tambah ekonomis (NITAMI). Di karenakan tingkat biaya modal lebih tinggi dibandingkan dengan tingkat pengembalian laba operasi perusahaan sebab adanya pesaing baru berupa transportasi online.
Therapeutic effect of YSY01 on osteoarthritis in rabbit: involvement of suppressing signaling pathway of NF-kB and MMP-9
Authors: Yang Zhou , Zhan Feng , Lin Shu-dian , Liu Ying , Zhan Yu-wei , Cheng Jiao-mei 
Published: April 2021

IntroductionIt has been reported that the NF-κB and MMP-9 signaling pathways were involved in the pathogenesis of osteoarthritis (OA), while the treatment of OA by YSY01 could inhibit the proteasome activity. Therefore, we aimed to study the therapeutic effect of YSY01A treatment on OA via interfering with expression of NF-κB and MMP-9.Material and methodsWestern blot analysis and immunohistochemistry (IHC) assays were used to measure the expression of NF-κB and MMP-9 in animal models established via SH treatment or cellular models established via sodium nitroprusside (SNP) treatment. MTT assay and flow cytometry analysis were performed to observe the effect of YSY01 treatment on cell viability and apoptosis.ResultsThe decreased expression of NF-κB and MMP-9 was observed in OA rabbits and cells treated by YSY01A, thus indicating the inhibitory effect of YSY01A on NF-κB and MMP-9 expression. And YSY01A exhibited a positive therapeutic effect on OA both in vivo and in vitro by inhibiting the expression of NF-κB and MMP-9. Meanwhile, YSY01A treatment could increase cell viability to a certain degree and decrease the apoptosis index, which suggested the application of YSY01A in OA therapy.ConclusionsThe levels of NF-κB and MMP-9 which were associated with aggravated apoptosis were up-regulated in OA models in vivo and in vitro. YSY01A treatment could down-regulate the expression of NF-κB and MMP-9 and inhibit cell apoptosis, thus reducing the severity of OA.
MiR-125b-5p enclosed in hypoxic HK2 cell-derived extracellular vesicles alleviates renal ischemia-reperfusion injury by regulating NLRC5
Authors: Xu Kai , Zhang Lifeng , Zhang Lei , Zhang Lei , Zhang Ze , Qian Siwei , Zou Xiangyu , Chen Shuqiu , Zuo Li , chen ming , Zhang Guangyuan 
Published: April 2021

IntroductionIn this study, we validated the changes in microRNA (miRNA) expression in hypoxic human kidney 2 (HK2) cell-derived extracellular vesicles (EVs). Additionally, we investigated the mechanism by which miRNA that are derived from EVs alleviated renal ischemia-reperfusion (I/R) injury.Material and methodsHK2 cells were treated in a hypoxic chamber (1% O2) for 12 h.EVs were obtained as supernatant from ultracentrifugation and characterized. After examining 16 differentially expressed EV-miRNAs between normoxic and hypoxic conditions by RT-PCR and bioinformatics analysis, miR-125b-5p was selected for further analysis. Normoxic and hypoxic HK2 cells-derived EVs as well as EVs that were isolated from miR-125b-5p negative control (miR-NC)-transfected or miR-125b-5p mimic (miR-MI)-transfected HK2 cells were injected in mice with renal I/R injury. The degree of renal injury was assessed by periodic acid-Schiff staining, renal tubule injury score, and plasma creatinine levels. Bioinformatics analysis was performed to determine the potential target genes of differentially expressed miRNAs. RT-PCR,western blotting, luciferase reporter assay, and immunohistochemistry were performed to investigate the relationship between miR-125b-5p and the NLR family CARD domain containing 5 (NLRC5).ResultsRT-PCR revealed that from 16 differentially expressed miRNAs, four EV-miRNAs were upregulated. Animal study showed that miR-125b-5p overexpression in EVs alleviated renal I/R injury. Bioinformatics analysis predicted that NLRC5 was targeted by miR-125b-5p. Moreover, the relationship between miR-125b-5p and NLRC5 was also validated.ConclusionsThere were several miRNAs that were upregulated (including miR-125b-5p) in hypoxic HK2 cells. Hypoxia induced EVs that alleviate renal IRI, can be attributed to miR-125b-5p for targeting NLRC5.