bluuebunny/crossref_metadata_2025_split huggingface dataset:
Knowledge, Attitudes, and Perceptions towards COVID-19 Disease and Vaccinations: A Cross-sectional Study from a Developing Country
Authors: Masa'deh Majd , Alrabadi Nasr , Harun Sabariah Noor 
Published: December 2024

Background
The world has faced challenges in persuading developing nations to adopt COVID-19 vaccines. Despite initial vaccine campaigns, COVID-19 is a global health crisis, and regional and population vaccination efforts vary. Knowledge, attitudes, and views regarding COVID-19 vaccination reveal how well the community understands its value and effectiveness. Public health strategies and efforts to boost vaccination rates depend on this understanding. Thus, this study examined the knowledge, attitudes, and practices of adults from a developing country toward the COVID-19 vaccination and their post-vaccination experience.

Methods
A dual-language (Arabic and English) questionnaire was developed and validated to assess COVID-19 vaccination knowledge, attitudes, and perceptions of the participants. The study questionnaire was developed and validated as an instrument. The questionnaire was distributed via Google Forms for a cross-sectional study, and all analyses were carried out using IBM SPSS.

Results
Six hundred thirty-five participants between 18 and 60 years responded to the questionnaire. The majority of respondents were female (64.3%) and middle-income (500-1000 JOD/month) (43.9%). Chronic illnesses were absent in 87.9% of participants. At least one COVID-19 immunization was given to 90.7% of them. COVID-19-infected people had more knowledge about the disease (B= 0.537; p=0.037). Greater COVID-19 vaccine knowledge was also linked with greater monthly income (B= 0.232; p=0.032) and postgraduate education (B= 0.405; p=0.014). Postgraduate education was also associated with higher positive views of COVID-19 immunization (B= 1.160; p=0.029). COVID-19-infected people were less likely to support vaccination (B= -0.758; p=0.024).

Conclusion
The study found that individuals understand and approve of the COVID-19 vaccine. They were rational and optimistic about the COVID-19 vaccine. Various characteristics that improve vaccination knowledge, attitudes, and perceptions were also explored. To ascertain long-term COVID-19 protection, vaccination attitudes and post-vaccination experiences of the people must be assessed as knowledge and attitudes change. This information may be useful for booster dose and immunization campaign messages. Conducting and reporting studies help policymakers to make informed decisions as knowledge, attitudes, and perceptions change during pandemics.
Komunitas Waria dan Politik Moralitas Pemerintah Orde Baru di Jakarta Tahun 1968-1998
Authors: Al Fikri Aditya Wahyu 
Published: December 2024

Tujuan penelitian ini adalah untuk merekonstruksi kehidupan komunitas waria di Jakarta, menganalisis komunitas waria di tangan Gubernur Ali Sadikin, dan praktik politik moralitas yang diterapkan pemerintah Orde Baru untuk membatasi ruang gerak komunitas waria di Jakarta Tahun 1968-1998. Penelitian ini akan disajikan dengan menggunakan metode historis sebagai landasan penelitian. Penelitian ini menggunakan pendekatan interdisipliner dari ilmu-ilmu sosial, yaitu studi gender, sosial, dan kultural, sehingga metode sejarah didukung dengan teori gender, sosiologi, dan antropologi. Ketiga pendekatan ilmu sosial tersebut dianggap cocok untuk menjawab pertanyaan bagaimana dan mengapa komunitas waria terjadinya kesenduan di Jakarta tahun 1968-1998. Komunitas waria mendapatkan perhatian khusus pada masa pemerintahan Gubernur Ali Sadikin pada tahun 1968. Gubernur Ali Sadikin selalu mengikutsertakan komunitas waria sebagai partisipasi pameran Jakarta Fair dengan menari, menyanyi, dan sulap pada tahun 1968. Komunitas waria mengalami keredupan dalam eksistensinya dengan adanya politik moralitas yang diterapkan oleh pemerintah Orde Baru pada tahun 1974. Komunitas waria mendapatkan perlakuan intoleransi dari masyarakat dengan diterapkannya politik moralitas yang dilakukan. Politik moralitas yang diterapkan pemerintah Orde Baru membentuk konsep ideologi gender maskulinitas dan feminitas yang mengatur masyarakat Indonesia dalam berpakaian dan bertingkah laku. Pemerintah menerapkan Gerakan Disiplin Nasional (GDN) untuk merazia komunitas waria yang melakukan nyebong di pinggir jalan dan rel kereta api. Kata Kunci: Komunitas Waria, Ali Sadikin, Pemerintah Orde Baru, Politik Moralitas.
Identifying Adolescent Depression and Anxiety Through Real-World Data and Social Determinants of Health: Machine Learning Model Development and Validation
Authors: Mardini Mamoun T , Khalil Georges E , Bai Chen , DivaKaran Aparna Menon , Ray Jessica M 
Published: December 2024

Abstract

Background
The prevalence of adolescent mental health conditions such as depression and anxiety has significantly increased. Despite the potential of machine learning (ML), there is a shortage of models that use real-world data (RWD) to enhance early detection and intervention for these conditions.

Objective
This study aimed to identify depression and anxiety in adolescents using ML techniques on RWD and social determinants of health (SDoH).

Methods
We analyzed RWD of adolescents aged 10‐17 years, considering various factors such as demographics, prior diagnoses, prescribed medications, medical procedures, and laboratory measurements recorded before the onset of anxiety or depression. Clinical data were linked with SDoH at the block-level. Three separate models were developed to predict anxiety, depression, and both conditions. Our ML model of choice was Extreme Gradient Boosting (XGBoost) and we evaluated its performance using the nested cross-validation technique. To interpret the model predictions, we used the Shapley additive explanation method.

Results
Our cohort included 52,054 adolescents, identifying 12,572 with anxiety, 7812 with depression, and 14,019 with either condition. The models achieved area under the curve values of 0.80 for anxiety, 0.81 for depression, and 0.78 for both combined. Excluding SDoH data had a minimal impact on model performance. Shapley additive explanation analysis identified gender, race, educational attainment, and various medical factors as key predictors of anxiety and depression.

Conclusions
This study highlights the potential of ML in early identification of depression and anxiety in adolescents using RWD. By leveraging RWD, health care providers may more precisely identify at-risk adolescents and intervene earlier, potentially leading to improved mental health outcomes.
MILESTONES IN THE FORMATION OF THE DEPARTMENT OF TRAUMATOLOGY, ORTHOPAEDICS AND NEUROSURGERY
Authors: Kovalchuk Р. , Vasyuk V. , Tulyuluk S. 
Published: December 2024

The creation in the following years of the departments of traumatology and orthopedics in Ukraine was an important step forward in the further development of traumatology and orthopedics as a science and subject of teaching. The departments of traumatology and orthopedics dealt with the issues of prevention, diagnostics and treatment of injuries and diseases of the musculoskeletal system, the organization of traumatological medical care. The Department of Traumatology, Orthopedics and Neurosurgery of the BSMU has gone through a diffi historical path of development. Today, the areas of activity of the department are educational, educational-methodical, medical and scientifi work, advanced training of orthopedic traumatologists. The department continues the best traditions of the past and at a high level trains medical personnel who successfully implement in practical activities the acquired knowledge in orthopedics, traumatology and neurosurgery. Over the years of its activity, the department has made a signifi contribution to the treasury of Ukrainian medical science, therefore it becomes necessary to highlight the historical stages of development and the characteristic features of its activities over all the years of its existence.
Kontekstualisasi QS Al-Isrā (17): 31 tentang Larangan Pembunuhan Anak Pendekatan Tafsir Kontekstual Abdullah Saeed
Authors: Putri Zahfa Lisnaeni , Naqiyah Naqiyah 
Published: December 2024

Idealnya anak merupakan anugrah yang diamanahkan Allah kepada hamba-Nya sehingga harus dilindungi dan dipenuhi hak-haknya. Akan tetapi, akhir-akhir ini tidak sedikit terjadi pembunuhan dan kekerasan terhadap anak dalam aneka ragam bentuknya. Pembunuhan terhadap anak sudah terjadi pada zaman Jahiliyah, sebagaimana telah direspon Al-Qur’an dalam surah Al-Isrā (17): 31. Disebutkan bahwa masyarakat Jahiliyah membunuh anak-anak perempuan mereka karena takut akan terjadinya kemiskinan, namun tidak sedikit orang tua di zaman sekarang membunuh anaknya dengan berbagai macam sebab yakni bukan hanya takut miskin. Oleh karena itu, kami tertarik untuk mengkaji lebih dalam mengenai QS Al-Isrā (17): 31. Tujuan penelitian ini adalah untuk mengetahui relevansi QS Al-Isrā (17): 31 tentang larangan membunuh anak karena takut miskin, dengan menggunakan teori kontekstual Abdullah Saeed. Hasil penelitian ini adalah: QS Al-Isrā (17): 31 mengandung larangan membunuh (dalam bentuk instruktif dan universal). Jika dikontekstualisasikan, larangan tersebut dapat diperluas jenisnya pada aneka ragam kekerasan fisik, psikis, seksual, dan ekonomi. Demikian juga penyebabnya bukan hanya karena faktor ekonomi, tetapi dapat mencakup faktor lainnya seperti masalah keluarga, sosial, dan politik. Penelitian ini merupakan kajian kualitatif dengan jenis kepustakaan (library search) dengan sumber primer QS Al-Isrā (17): 31 dan sumber sekunder berupa kamus Al-Qur’an, kitab-kitab tafsir, artikel dalam jurnal, dan literatur lain yang relevan.
Makna Sāil dalam Al-Qur’an Perspektif Tafsir Maqasidi
Authors: Nur Hamidah Tysa 
Published: December 2024

Fenomena meminta-minta hingga saat ini masih menjadi salah satu permasalahan sosial yang tidak dapat dipisahkan dari realita kehidupan di masyarakat. Peminta dalam al-Qur’an disebut sebagai sāil, penyebutan ini bersamaan dengan kalimat pemberian harta, baik berupa sedekah maupun zakat. Penelitian ini merupakan jenis penelitian kepustakaan (library research). Adapun pendekatannya yaitu menggunakan Tafsir maqāṣid yang dikembangkan oleh Abdul Mustaqim. Tujuan dengan pendekatan ini yaitu untuk mengupas maksud dan tujuan penafsiran kata sāil dalam al-Qur’an dengan mempertimbangkan beberapa nilai-nilai kemaslahatan Maqāṣid al-Qur’an dan Maqāṣid as-syari’ah untuk merealisasikan kemaslahatan dan menolak kerusakan. Hasil dari penelitian ini, penulis menemukan beberapa nilai-nilai kemaslahatan yang terkandung dalam kata sāil yaitu; nilai kemanusian (berlaku baik terhadap sesama), nilai tanggungjawab (melindungi dan menjaga kesejahteraan sosial), dan nilai keadilan (keseimbangan antara pertumbuhan dan pemetaan). Adapun aspek-aspek yang terkandung dalam kata sāil yaitu; hifẓ an-nafs, hifẓ al-din, dan hifẓ an-nasl.
BUKU ELEKTRONIK SCOUTING EDUCATION BERBASIS KURIKULUM OUTCOME BASED EDUCATION (OBE) DI FAKULTAS ILMU KEOLAHRAGAAN
Authors: Damanik Saipul Ambri , Damanik Suryadi , Muhammad Chairad  , Al Husna  
Published: December 2024

Penelitian ini bertujuan menghasilkan produk berupa buku elektronik (e-book) berbasis Kurikulum Outcome Based Education (OBE) sebagai literasi teknologi, sumber belajar serta media alternatif, yang dapat memudahkan cara belajar mahasiswa, dirancang sesuai dengan karakteristik mahasiswa, dengan harapan dapat dapat meningkatkan minat baca, pengetahuan dan untuk bahan menyelesaikan tugas Critical Book Report (CBR) terhadap mahasiswa Prodi Pendidikan Jasmani Kesehatan dan Rekreasi. Metode penelitian yang digunakan yaitu penelitian dan pengembangan (Research and Development). Penelitian dilaksanakan pada bulan Juni sampai dengan September tahun 2024 di Program Studi PJKR FIK Universitas Negeri Medan dengan subyek penelitian yakni mahasiswa PJKR yang mengambil matakuliah Kepramukaan. Instrumen pengumpulan data yang digunakan dalam penelitian ini yaitu instrumen angket penilaian e-book. Hasil penilaian menunjukkan bahwa pada buku elektronik scouting education berbasis kurikulum outcome based education memiliki kesesuaian materi dengan capaian pembelajaran lulusan sudah sesuai, materi ajar dan pendalaman materi ajar sudah sesuai, kelengkapan penyajian dan kebahasaan sudah sesuai dan kemudahan penggunaan e-book yang dapat digunakan oleh mahasiswa secara mandiri.
Kata Kunci : E-Book, Kurikulum OBE
A Review of Theoretical Approach to Sweetness in Chemical Compounds
Authors: Yuniarta Tegar Achsendo , Putra Purnawan Pontana 
Published: December 2024

The relationship between humans and the sweet sensation is a challenge in itself. The concept of taste undergoes dynamic transformations throughout human civilization, reflecting individuals evolving preferences and experiences. Taste, as an experiential phenomenon, intricately involves the physiological aspects of the human body, with a direct correlation to signal transmission within the brain. The primary objective of this study is to unravel the chemical characteristics that contribute to the generation of sweet flavours. The research investigates the complex interplay between chemical structures and taste perception by utilizing a comprehensive review of literature from diverse sources, including books and scholarly articles from various publishers. Various analytical techniques, such as ligand-based glucophore modeling, quantitative structure-activity relationships, and the prediction and discovery of sweet receptors, are employed to understand the effects of chemical structures on sweetness. By exploring how the chemical composition of substances influences taste, this research aims to provide valuable insights into the molecular foundations of flavour, advancing our understanding of the complexities that underlie the human gustatory experience.

Submitted: 27-08-2024, Revised: 29-10-2024, Accepted: 24-12-2024, Published regularly: December 2024
Optimasi Rasio Cocoa Butter dan Minyak Jarak pada Stabilitas Lip Balm Stick Ekstrak Lidah Buaya (Aloe vera Linn.)
Authors: Muntu Cynthia Marisca , Nahri Santi Amalia An , Wahjuningsih Endang 
Published: December 2024

Lip balm merupakan produk perawatan bibir yang sangat esensial karena fungsinya dalam menjaga kelembapan dan memberikan proteksi terhadap kekeringan. Kombinasi cocoa butter dan minyak jarak sering digunakan dalam formulasi lip balm karena sifatnya yang melembapkan, namun rasio yang tidak tepat dapat mempengaruhi stabilitas dan tekstur produk. Ekstrak lidah buaya (Aloe vera Linn.) memberikan tambahan manfaat dalam melembapkan dan menyejukkan, sehingga meningkatkan khasiat lip balm. Penelitian ini bertujuan untuk mengamati kesesuaian lip balm dengan spesifikasi dan memperoleh rasio cocoa butter dan minyak jarak terbaik berdasarkan karakteristik dan stabilitasnya. Lip balm diformulasikan dalam tiga formula yang bervariasi pada rasio cocoa butter dan minyak jarak, masing-masing adalah 10:44,2 (formula I), 11:43,2 (formula II) dan 12:42,2 (formula III). Kondisi penyimpanan produk dikondisikan pada suhu 40 °C dan RH 75% ± 5% selama 30 hari. Keseluruhan formula lip balm memenuhi seluruh spesifikasi yaitu organoleptis, kekerasan, berat jenis, titik lebur, spreadability dan pH. Rasio cocoa butter dan minyak jarak mempengaruhi karakteristik titik lebur dan pH lip balm. Lip balm lidah buaya formula II dengan rasio cocoa butter dan minyak jarak 11:43,2 merupakan formula terbaik yang stabil pada keseluruhan parameter.

Lip balm is an essential lip care product due to its function in maintaining moisture and providing protection against dryness. A combination of cocoa butter and castor oil is commonly used in lip balm formulations due to its moisturizing properties; however, an incorrect ratio can affect the product stability and texture. Aloe vera (Aloe vera Linn.) extract provides additional benefits in terms of hydration and soothing, thereby enhancing the efficacy. This study aims to evaluate the conformity of the lip balm with specified standards and to determine the optimal ratio of cocoa butter to castor oil based on its stability. The lip balm was formulated in three different formulations with varying cocoa butter and castor oil ratios: 10:44.2 (formula I), 11:43.2 (formula II), and 12:42.2 (formula III). Storage conditions were set at 40 °C and RH 75% ± 5% for 30 days. All formulations met the pecifications, including organoleptic properties, hardness, specific gravity, melting point, spreadability, and pH. The cocoa butter-to-castor oil ratio influenced the melting point and pH characteristics of the lip balm. Lip balm formula II, with a cocoa butter and castor oil ratio of 11:43.2, was the best formula, stable across all parameters.

Submitted: 10-11-2024, Revised: 29-11-2024, Accepted: 05-12-2024, Published regularly: December 2024
Dinamik Chaos pada Sistem Burke-Shaw Fraksional Caputo Berorde Sama
Authors: Filla M. Shiqo , John Peter , Tasman Hengki 
Published: December 2024

Operator turunan fraksional telah diterapkan pada berbagai bidang pemodelan, salah satunya pada model sistem dinamik yang bersifat chaos. Sistem chaos umumnya menggunakan sistem persamaan diferensial berorde integer, namun berbagai penelitian telah menunjukkan bahwa chaos juga dapat terjadi pada sistem dengan turunan berorde fraksional. Pada artikel ini dibahas chaos pada sistem Burke-Shaw fraksional Caputo berorde sama. Diperoleh hasil bahwa fenomena chaos dapat terjadi saat orde turunan fraksional yang diterapkan pada model berada pada interval tertentu. Diselidiki juga dinamik solusi dari sistem Burke-Shaw fraksional saat orde-orde turunan fraksional yang berbeda diterapkan pada sistem dengan mengamati potret fase dari solusi sistem dan nilai eksponen Lyapunov yang diperoleh secara numerik. Dinamik dari solusi sistem juga diamati untuk melihat sensitivitas solusi terhadap perturbasi nilai awal
Automatic Hemangioma Detection Algorithm Using a Cascade of K-Means and Active Contour Model
Authors: Cătălina Neghină , Alina Sultana 
Published: December 2024

Abstract
Although mostly harmless, hemangiomas still need to be monitored and occasionally treated to avoid complications. The method presented for accurately segmenting the hemangioma pixels involves the automatic detection of the number of classes in an initial k-means clustering, followed by binarization, morphological operations and a further adjustment of region of interest using active contours. The method has been tested on a database containing a variety of situations, including multiple hemangioma areas, differently colored and textured skin and intrusive hair. Compared to the results before the addition of active contours, the mean global score shows an improvement of more than 1% (from 96.86% to 97.92%).
Hemolysis due to anti-IH in a patient with beta-thalassemia and Mycoplasma pneumoniae infection
Authors: Chousal Jennifer N. , Sargolzaeiaval Forough , Huynh Tridu R. , Zhao Mitchell , Rodberg Karen , Kopko Patricia M. , Gopal Srila , Allen Elizabeth S. 
Published: December 2024

Abstract
Anti-IH is a common cold agglutinin that is typically clinically insignificant. We present a case that resulted in hemolysis. A 32-year-old male patient with transfusion-independent beta-thalassemia intermedia presented with symptomatic anemia. His blood sample typed as group B, D+ and demonstrated multiple alloantibodies and cold autoantibodies. He was transfused uneventfully, but re-presented 10 days later with recurrent, worsening anemia. At this time, transfusion of group O, phenotype-matched red blood cells (RBCs) resulted in an acute hemolytic reaction. While anemia was initially attributed to drug-mediated bone marrow toxicit y and subsequently to a delayed hemolytic reaction, further evaluation revealed Mycoplasma pneumoniae infection and a cold agglutinin (anti-IH specificity), indicating a likely autoimmune-mediated anemia due to an infectious etiology. Subsequent transfusion of 2 group B, phenotype-matched RBC units using a blood warmer was uneventful. Anti-IH is only rarely associated with hemolytic transfusion reactions, which may be exacerbated when transfusing group O RBC units to group B patients. M. pneumoniae infection likely led to cold agglutinin–mediated hemolysis of endogenous and transfused RBCs. The patient was successfully managed with intravenous immunoglobulin, steroids, rituximab, erythropoietin, hydroxyurea, and amoxicillin clavulanate/azithromycin. This case illustrates the importance of infectious disease evaluation in patients with unexplained anemia, the potential clinical significance of autoanti-IH, and the value of providing type-specific RBC units in these circumstances.
Anti-G evaluations in D– pregnant women determine the need for Rh immune globulin prophylaxis: report of two illustrative cases
Authors: Jaladi Soumya , Cao Wenjing , Meinecke Daniel R. , Ruegsegger Patricia A. , Weiss John , Rhoades Janine , Connor Joseph 
Published: December 2024

Abstract
Distinguishing anti-D, anti- C, and anti-G specificities is particularly essential in antenatal cases to ensure proper patient management. The clinical management as well as Rh immune globulin (RhIG) prophylaxis depend on the accurate identification of these distinct antibodies. D− pregnant women with anti-G, but without anti-D, in their serum need RhIG prophylaxis at 28 weeks of gestation, at delivery if the infant is D+, and when clinically indicated to prevent the formation of anti-D and potential hemolytic disease of the fetus and newborn (HDFN). We present two cases in which determining the antibody specificities determined the course of the patient’s treatment. In one case, a 30-year-old, gravida-1, para-0 woman with blood group A, D− and with no previous RhIG administration had the presence of anti-D, -C, and -G in her plasma. Because she had already been alloimmunized and developed anti-D, RhIG prophylaxis was not necessary. In another case, a 37-year-old, gravida-2, para-1 woman with blood group A, D− and no prior RhIG administration had anti-C and anti-G in her plasma. Because she was not sensitized to D, she needed RhIG prophylaxis. In conclusion, pregnant women can develop anti-C and/or anti-G in the absence of anti-D. Therefore, studies should be conducted to differentiate anti-D, -C, and -G in pregnant women who are presumptively identified as having anti-D and anti-C when their medical history (RhIG prophylactic therapy) suggests that anti-D may not actually be present. In the absence of anti-D, pregnant women should receive prophylaxis with RhIG to prevent alloimmunization to D. For pregnant women who are already sensitized to D, RhIG prophylaxis is not needed.