bluuebunny/crossref_metadata_2025_split huggingface dataset:
The trace fossilPolykampton recurvumn. isp. (sequestrichnia) from the Maastrichtian–Paleocene deep-sea deposits of NW Italy
Authors: Uchman Alfred , Rattazzi Bruno 
Published: August 2021

AbstractPolykampton recurvumn. isp. is the sixth ichnospecies of the ichnogenusPolykamptonOoster, 1869. It is a horizontal structure composed of a median cylindrical tunnel and narrow, usually back-curved lateral lobes located in alternating position. It occurs 2–3 cm below the top of single beds in the Maastrichtian–Paleocene deep-sea turbiditic marlstones of the Monte Antola Unit in the Northern Apennines. The lobes ofP. recurvumn. isp. are actively filled with gray mudstone from above through the permanently open median tunnel. The trace fossil belongs to the category sequestrichnia, which is typical of oxygenated deep-sea environments characterized by seasonal or episodic supply of organic matter into a generally oligotrophic environment.P. recurvumn. isp. was produced by a “worm,” probably a polychaete, which adapted to seasonal or only episodic supply of organic matter to the deep-sea floor. The tracemaker stored the organic-rich mud in the lobes for nutrition during times of low organic matter availability on the seafloor.UUID:http://zoobank.org/49555117-1c39-4658-8b49-3f3e2f47ba27
LIE ALGEBRA MODULES WHICH ARE LOCALLY FINITE AND WITH FINITE MULTIPLICITIES OVER THE SEMISIMPLE PART
Authors: MAZORCHUK VOLODYMYR , MRÐEN RAFAEL 
Published: August 2021

AbstractFor a finite-dimensional Lie algebra
$\mathfrak {L}$
over
$\mathbb {C}$
with a fixed Levi decomposition
$\mathfrak {L} = \mathfrak {g} \ltimes \mathfrak {r}$
, where
$\mathfrak {g}$
is semisimple, we investigate
$\mathfrak {L}$
-modules which decompose, as
$\mathfrak {g}$
-modules, into a direct sum of simple finite-dimensional
$\mathfrak {g}$
-modules with finite multiplicities. We call such modules
$\mathfrak {g}$
-Harish-Chandra modules. We give a complete classification of simple
$\mathfrak {g}$
-Harish-Chandra modules for the Takiff Lie algebra associated to
$\mathfrak {g} = \mathfrak {sl}_2$
, and for the Schrödinger Lie algebra, and obtain some partial results in other cases. An adapted version of Enright’s and Arkhipov’s completion functors plays a crucial role in our arguments. Moreover, we calculate the first extension groups of infinite-dimensional simple
$\mathfrak {g}$
-Harish-Chandra modules and their annihilators in the universal enveloping algebra, for the Takiff
$\mathfrak {sl}_2$
and the Schrödinger Lie algebra. In the general case, we give a sufficient condition for the existence of infinite-dimensional simple
$\mathfrak {g}$
-Harish-Chandra modules.
Understanding the State Regulation of Fatherhood in Latin America: Complementary versus Co-responsible
Authors: Martínez Franzoni Juliana 
Published: August 2021

AbstractFatherhood is a key but missing component of research on welfare regimes. What do states formally demand from fatherhood across Latin America? Using a novel data set of coded legal and policy provisions for 19 Latin American countries, this article offers a conceptual framework to examine state interventions targeting biological, caregiving and breadwinning dimensions of fatherhood. My findings show that, regardless of how robust their social policies are, most countries presume fatherhood to be complementary rather than co-responsible to motherhood. By making a conceptual, empirical and practical contribution to studying the state regulation of fatherhood, this article contributes to a more comprehensive view of welfare regimes.
Variations by ethnicity in referral and treatment pathways for IAPT service users in South London
Authors: Harwood Hannah , Rhead Rebecca , Chui Zoe , Bakolis Ioannis , Connor Luke , Gazard Billy , Hall Jheanell , MacCrimmon Shirlee , Rimes Katharine A. , Woodhead Charlotte , Hatch Stephani L. 
Published: August 2021

AbstractBackgroundThe Improving Access to Psychological Therapies (IAPT) programme aims to provide equitable access to therapy for common mental disorders. In the UK, inequalities by ethnicity exist in accessing and receiving mental health treatment. However, limited research examines IAPT pathways to understand whether and at which points such inequalities may arise.MethodsThis study examined variation by ethnicity in (i) source of referral to IAPT services, (ii) receipt of assessment session, (iii) receipt of at least one treatment session. Routine data were collected on service user characteristics, referral source, assessment and treatment receipt from 85 800 individuals referred to South London and Maudsley NHS Foundation Trust IAPT services between 1st January 2013 and 31st December 2016. Multinomial and logistic regression analysis was used to assess associations between ethnicity and referral source, assessment and treatment receipt. Missing ethnicity data (18.5%) were imputed using census data and reported alongside a complete case analysis.ResultsCompared to the White British group, Black African, Asian and Mixed ethnic groups were less likely to self-refer to IAPT services. Black Caribbean, Black Other and White Other groups are more likely to be referred through community services. Almost all racial and minority ethnic groups were less likely to receive an assessment compared to the White British group, and of those who were assessed, all racial and ethnic minority groups were less likely to be treated.ConclusionsRacial and ethnic minority service users appear to experience barriers to IAPT care at different pathway stages. Services should address potential cultural, practical and structural barriers.
Effect of older adults in the family on the sandwich generation's pursuit of entrepreneurship: evidence from China
Authors: Liu Yiwei , Wang Wenjing , Cong Zhen , Chen Zhirui 
Published: August 2021

AbstractHousehold entrepreneurship is a basic unit of entrepreneurial activity, and a crucial aspect of connecting personal and social wellbeing. This study examines the relationship between the proportion of elderly family members and household entrepreneurship. This study also assesses the mediating effect of the middle-aged generation's support to their parents and the moderating effect of the parents’ support with respect to the proportion of elderly family members and entrepreneurship. We use data from the China Family Panel Studies. We adopt the instrumental variable method to deal with endogeneity, robustness and credibility of the estimation results. The results show that a higher proportion of elderly family members impedes household entrepreneurship. Moreover, the financial and instrumental support provided by the middle-aged generation to their parents significantly mediates the relationship between the proportion of elderly family members and household entrepreneurship. In turn, parents’ financial support to the middle-aged generation moderates the focal relationship; however, parents’ instrumental support does not moderate the focal relationship. These findings emphasise the need to develop a comprehensive social security network for older adults that will indirectly promote household entrepreneurship, and improve personal and social wellbeing.
Developing a Healthcare Technology Acceptance Model (H-TAM) for Older Adults with Hypertension
Authors: Harris Maurita T. , Rogers Wendy A. 
Published: August 2021

AbstractOlder adults with a chronic health condition (e.g. hypertension) use various self-management methods. Healthcare technologies have the potential to support health self-management. However, it is necessary to understand the acceptance of these technologies as a precursor to older adults’ adoption and integration into their health plan. Our focus was on the factors older adults with hypertension initially consider when introduced to three new healthcare technologies that might support their health self-management. We compared their considerations for a blood pressure monitor, an electronic pillbox and a multifunction robot to simulate incrementally more complex technologies. Twenty-three participants (aged 65–84) completed four questionnaires and a semi-structured interview. The interview transcripts were analysed using a thematic analysis approach. We identified the factors that were frequently mentioned among the participants for each of the three healthcare technologies. The factors that older adults initially considered were familiarity, perceived benefits, perceived ease of use, perceived need for oneself, relative advantage, complexity and perceived need for others. Upon further reflection, participants considered advice acceptance, compatibility, convenience, facilitating conditions, perceived usefulness, privacy, subjective norm, and trust. We integrated the factors that older adults considered into the Healthcare Technology Acceptance Model (H-TAM), which elucidates the complexity of healthcare technology acceptance and provides guidance for future explorations.
Cooperation between the EU and China: A post-liberal governmentality approach
Authors: Fanoulis Evangelos , Song Weiqing 
Published: August 2021

AbstractThe European Union's partnership with China has received significant academic attention. Experts have focused on both parties’ economic and political objectives and have made efforts to grasp the dynamics of the institutionalisation of EU-China cooperation. However, little has been said about how this collaboration affects the lives of citizens, especially in China. Adopting a Foucauldian epistemology, this article's key contention is that EU-China cooperation imposes a joint form of post-liberal governmental power on the Chinese population, which socially constructs empowered but not liberal political subjectivities for Chinese citizens. The article first reviews Foucault's approach to governmentality. It then explores Sino-EUropean collaboration after 2013, when the two partners established the ‘EU-China 2020 Strategic Agenda for Cooperation’. We illustrate how the institutionalisation of the partnership has been consistent with a governmentalised political rationality, and how policy implementation has allowed a post-liberal form of governmental power to flow from both EU and Chinese policymakers towards the Chinese population, triggering processes of political subjectivisation.
Spatial analysis of the incidence of Dengue, Zika and Chikungunya and socioeconomic determinants in the city of Rio de Janeiro, Brazil
Authors: Queiroz Eny Regina da Silva , Medronho Roberto de Andrade 
Published: August 2021

Abstract
In 2015–2016, simultaneous circulation of dengue, Zika and chikungunya in the municipality of Rio de Janeiro (Brazil) was reported. We conducted an ecological study to analyse the spatial distribution of dengue, Zika and chikungunya cases and to investigate socioeconomic factors associated with individual and combined disease incidence in 2015–2016. We then constructed thematic maps and analysed the bivariate global Moran indices. Classical and spatial models were used. A distinct spatial distribution pattern for dengue, Zika and chikungunya was identified in the municipality of Rio de Janeiro. The bivariate global Moran indices (P < 0.05) revealed negative spatial correlations between rates of dengue, Zika, chikungunya and combined arboviruses incidence and social development index and mean income. The regression models (P < 0.05) identified a negative relationship between mean income and each of these rates and between sewage and Zika incidence rates, as well as a positive relationship between urban areas and chikungunya incidence rates. In our study, spatial analysis techniques helped to identify high-risk and social determinants at the local level for the three arboviruses. Our findings may aid in backing effective interventions for the prevention and control of epidemics of these diseases.
Impact of COVID-19 on the indigenous population of Brazil: a geo-epidemiological study
Authors: Alves Josilene D. , Abade André S. , Peres Wigis P. , Borges Jonatas E. , Santos Sandra M. , Scholze Alessandro R. 
Published: August 2021

Abstract
This study aimed to analyse the geographical distribution of coronavirus disease 2019 (COVID-19) and to identify high-risk areas in space and time for the occurrence of cases and deaths in the indigenous population of Brazil. This is an ecological study carried out between 24 March and 26 October 2020 whose units of analysis were the Special Indigenous Sanitary Districts. The Getis-Ord General G and Getis-Ord Gi* techniques were used to verify the spatial association of the phenomena and a retrospective space–time scan was performed. There were 32 041 confirmed cases of COVID-19 and 471 deaths. The non-randomness of cases (z score = 5.40; P < 0.001) and deaths (z score = 3.83; P < 0.001) were confirmed. Hotspots were identified for cases and deaths in the north and midwest regions of Brazil. Sixteen high-risk space–time clusters were identified for the occurrence of cases with a higher RR = 21.23 (P < 0.001) and four risk clusters for deaths with a higher RR = 80.33 (P < 0.001). These clusters were identified from 22 May and were active until 10 October 2020. The results indicate critical areas in the indigenous territories of Brazil and contribute to better directing the actions of control of COVID-19 in this population.
INTERSECTION COHOMOLOGY OF THE MODULI SPACE OF HIGGS BUNDLES ON A GENUS 2 CURVE
Authors: Felisetti Camilla 
Published: August 2021

AbstractLetCbe a smooth projective curve of genus$2$. Following a method by O’Grady, we construct a semismall desingularisation$\tilde {\mathcal {M}}_{Dol}^G$of the moduli space$\mathcal {M}_{Dol}^G$of semistableG-Higgs bundles of degree 0 for$G=\mathrm {GL}(2,\mathbb {C}), \mathrm {SL}(2,\mathbb {C})$. By the decomposition theorem of Beilinson, Bernstein and Deligne, one can write the cohomology of$\tilde {\mathcal {M}}_{Dol}^G$as a direct sum of the intersection cohomology of$\mathcal {M}_{Dol}^G$plus other summands supported on the singular locus. We use this splitting to compute the intersection cohomology of$\mathcal {M}_{Dol}^G$and prove that the mixed Hodge structure on it is pure, in analogy with what happens to ordinary cohomology in the smooth case of coprime rank and degree.
Laufen gegen die Depression
Authors: Traber Rahel 
Published: August 2021

Was ist zu diesem Thema bekannt? Es wurden bereits viele Studien zu diesem Thema veröffentlicht, welche den positiven Effekt von sportlicher Aktivität auf Depressionen bestätigen. Aufgrund der Fülle an Studien können die Resultate als aussagekräftig betrachtet werden. Wie wird eine neue Perspektive eingebracht? Neben dem zu erwartenden Effekt auf die depressive Symptomatik wurden zusätzliche signifikante Ergebnisse in den Bereichen der sozialen Beziehungen, der Stimmungslage sowie des Angst- und Stresslevels nachgewiesen. Was sind die Auswirkungen auf die Praxis? Aufgrund der aussagekräftigen Resultate kann sportliche Aktivität gezielt und evidenzgestützt in die Therapie von depressiven Patientinnen und Patienten aber auch in anderen Fachgebieten der Psychiatrie einbezogen werden.
Optimizing Lake Surface Water Temperature Simulations Over Large Lakes in China With FLake Model
Authors: Huang Ling , Wang Xuhui , Sang Yuxing , Tang Shuchang , Jin Lei , Yang Hui , Ottlé Catherine , Bernus Anthony , Wang Shenglei , Wang Chenzhi , Zhang Yuan 
Published: August 2021

AbstractLake surface water temperature (LSWT) is sensitive to climate change; however, simulated LSWT and its response to climate change remain uncertain. In this study, FLake, a one‐dimensional freshwater lake model, is optimized to simulate the LSWTs of 94 large lakes with surface areas greater than 100 km2 in China. While most of these lakes are seasonally ice‐covered over the Tibetan Plateau, FLake with default parameters significantly underestimated LSWT in spring and winter and slightly overestimated LSWT in summer and autumn in seasonally ice‐covered lakes. We performed sensitivity experiments and calibration in the trial lake (Qinghai Lake). Then, parameter calibrations of three lake‐specific properties (albedo, lake mean depth and light extinction coefficient) were performed in all the studied lakes. The optimized FLake substantially improved the simulations of seasonal and interannual variations in LSWT. The root mean square error decreased from 3.64 ± 1.54°C to 1.97 ± 0.72°C, and the mean bias of 96% of the lakes decreased to less than 1°C. Our study showed that the optimized FLake can reproduce the temporal variations in LSWT across China with optimized parameters, providing the possibility to simulate and project the response of LSWT to rapid climate change.
Quantifying Contributions of External Drivers to the Global Ionospheric State
Authors: Meng Xing , Verkhoglyadova Olga P. 
Published: August 2021

AbstractTo advance our understanding of the global response of the ionospheric total electron content (TEC) to various external drivers, we apply entropy‐based information theory to quantify contributions of solar, interplanetary, and lower atmospheric drivers to the global ionospheric state described by the Global Ionospheric Map (GIM). By computing normalized transfer entropy on 18 years of GIM TEC, F10.7, solar wind, and lower atmospheric data, we obtain the predictive information transfer from the present drivers to the global ionospheric state at various future times. We find that the solar extreme ultraviolet (EUV) irradiance dominates the information transfer within 3 days into the future, while the lower atmospheric migrating tidal sources dominate beyond 3 days into the future. The maximum information transfer from individual drivers reveals the maximum contributions from the drivers to the global ionospheric state. Among all drivers considered, the lower atmospheric migrating tidal sources contribute most. The solar EUV irradiance and tropospheric deep convection are secondary drivers with comparable contributions at about half of the contribution from migrating tidal sources. The interplanetary driving contributes the least to the global ionospheric state during both geomagnetic storm and quiet time, even though the contribution from the interplanetary magnetic field can enhance four to six times during geomagnetic storm time than quiet time.
Targeting serine hydroxymethyltransferases 1 and 2 for T-cell acute lymphoblastic leukemia therapy
Authors: Pikman Yana , Ocasio-Martinez Nicole , Alexe Gabriela , Dimitrov Boris , Kitara Samuel , Diehl Frances F. , Robichaud Amanda L. , Conway Amy Saur , Ross Linda , Su Angela , Ling Frank , Qi Jun , Roti Giovanni , Lewis Caroline A. , Puissant Alexandre , Vander Heiden Matthew G. , Stegmaier Kimberly 
Published: August 2021

AbstractDespite progress in the treatment of acute lymphoblastic leukemia (ALL), T-cell ALL (T-ALL) has limited treatment options, particularly in the setting of relapsed/refractory disease. Using an unbiased genome-scale CRISPR-Cas9 screen we sought to identify pathway dependencies for T-ALL which could be harnessed for therapy development. Disruption of the one-carbon folate, purine and pyrimidine pathways scored as the top metabolic pathways required for T-ALL proliferation. We used a recently developed inhibitor of SHMT1 and SHMT2, RZ-2994, to characterize the effect of inhibiting these enzymes of the one-carbon folate pathway in T-ALL and found that T-ALL cell lines were differentially sensitive to RZ-2994, with the drug inducing a S/G2 cell cycle arrest. The effects of SHMT1/2 inhibition were rescued by formate supplementation. Loss of both SHMT1 and SHMT2 was necessary for impaired growth and cell cycle arrest, with suppression of both SHMT1 and SHMT2 inhibiting leukemia progression in vivo. RZ-2994 also decreased leukemia burden in vivo and remained effective in the setting of methotrexate resistance in vitro. This study highlights the significance of the one-carbon folate pathway in T-ALL and supports further development of SHMT inhibitors for treatment of T-ALL and other cancers.
Structured 3D linear space–time light bullets by nonlocal nanophotonics
Authors: Guo Cheng , Xiao Meng , Orenstein Meir , Fan Shanhui 
Published: August 2021

AbstractWe propose the generation of 3D linear light bullets propagating in free space using a single passive nonlocal optical surface. The nonlocal nanophotonics can generate space–time coupling without any need for bulky pulse-shaping and spatial modulation techniques. Our approach provides simultaneous control of various properties of the light bullets, including the external properties such as the group velocity and the propagation distance, and internal degrees of freedom such as the spin angular momentum and the orbital angular momentum.
Pre-treatment clinical and gene expression patterns predict developmental change in early intervention in autism
Authors: Lombardo Michael V. , Busuoli Elena Maria , Schreibman Laura , Stahmer Aubyn C. , Pramparo Tiziano , Landi Isotta , Mandelli Veronica , Bertelsen Natasha , Barnes Cynthia Carter , Gazestani Vahid , Lopez Linda , Bacon Elizabeth C. , Courchesne Eric , Pierce Karen 
Published: August 2021

AbstractEarly detection and intervention are believed to be key to facilitating better outcomes in children with autism, yet the impact of age at treatment start on the outcome is poorly understood. While clinical traits such as language ability have been shown to predict treatment outcome, whether or not and how information at the genomic level can predict treatment outcome is unknown. Leveraging a cohort of toddlers with autism who all received the same standardized intervention at a very young age and provided a blood sample, here we find that very early treatment engagement (i.e., <24 months) leads to greater gains while controlling for time in treatment. Pre-treatment clinical behavioral measures predict 21% of the variance in the rate of skill growth during early intervention. Pre-treatment blood leukocyte gene expression patterns also predict the rate of skill growth, accounting for 13% of the variance in treatment slopes. Results indicated that 295 genes can be prioritized as driving this effect. These treatment-relevant genes highly interact at the protein level, are enriched for differentially histone acetylated genes in autism postmortem cortical tissue, and are normatively highly expressed in a variety of subcortical and cortical areas important for social communication and language development. This work suggests that pre-treatment biological and clinical behavioral characteristics are important for predicting developmental change in the context of early intervention and that individualized pre-treatment biology related to histone acetylation may be key.