bluuebunny/crossref_metadata_2025_split huggingface dataset:
SNMP for Cloud Environment Energy Efficiency
Authors: Chinnici Marta , Iqbal Asif , kor ah lian , pattinson colin , rondeau eric 
Published: September 2021

Abstract
Cloud computing has seen rapid growth and environments are now providing multiple physical servers with several virtual machines running on those servers. Networks have grown larger and have become more powerful in recent years. A vital problem related to this advancement is that it has become increasingly complex to manage networks. SNMP is one standard which is applied as a solution to this management of networks problem. This work utilizes SNMP to explore the capabilities of SNMP protocol and its features for monitoring, control and automation of virtual machines and hypervisors. For this target, a stage-wise solution has been formed that obtains results of experiments from the first stage uses SNMPv3 and feed to the second stage for further processing and advancement. The target of the controlling experiments is to explore the extent of SNMP capability in the control of virtual machines running in a hypervisor, also in terms of energy efficiency. The core contribution based on real experiments is conducted to provide empirical evidence for the relation between power consumption and virtual machines.
Quantitative Trait Loci Mapping of Stem oBrix Content and Stem Diameter in Sorghum Recombinant Inbred Lines Using Genotype-By-Sequencing
Authors: Deressa Abera Takele , Feyisa Tileye , Disasa Tesfaye 
Published: September 2021

Abstract
Sweet sorghum has the ability to store sugar in its stem. Many sugar content genes have been discovered and through breeding worldwide. However, some of these genes are unstable. This study aimed to detect and validate QTL for stem oBrix content from sorghum RILs. In two seasons, QTL linked with stem brix content and related traits were examined using 139 F8RILs from a grain and sweet sorghum. A genetic linkage map with 128 SNP markers was created and several QTLs were identified. Phenotypic variation between 6.33 and 14% was identified for a given trait. Over two seasons, four QTLs for stem brix content (qBrix2-1, qBrix4-1, qBrix4-2, and qBrix10-1) and three QTLs for stem diameter (qSD1-1, qSD8-1 and qSD9-1) were detected. The detected QTL could be useful for improving stem brix content in different growing season. Furthermore, it makes a significant contribution to marker-assisted brix selection and sorghum biofuel improvement.
Investigation on Ultra-compact 2DPC Coarse Wavelength Division Demultiplexer
Authors: Kannaiyan Venkatachalam , D Sriram Kumar , S Robinson 
Published: September 2021

Abstract
A two dimensional Photonic Crystal (2DPC) based eight channel wavelength division demultiplexer is proposed and designed for Coarse Wavelength Division Multiplexing (CWDM) applications. The circular ring resonator, channel selector, circulator rod, L bend waveguide and linear bus waveguide are essential parts of the proposed system. The system’s functional parameters such as Transmission efficiency, resonant wavelength, spectral width, channel spacing, Quality factor and crosstalk are investigated in this paper. The eight different wavelengths of channels are filtered out by altering the size of channel selector rod, setting the radius of the circle shaped cavity and relative refractive index of circulator rod. Initially the Photonic Band gap (PBG) is manipulated by applying Plane Wave Expansion (PWE) method of the 2DPC structure. The functional parameters are analysed by Finite Difference Time Domain (FDTD) method in periodic and non-periodic structure of the proposed system to arrive normalized transmission spectrum. The resonant wavelengths of designed eight paths of the device are varying from 1420nm to 1460nm with average spectral width and channel spacing are 5.8nm, 5.6nm respectively. The footprint of the device is 286.84µm2. Hence this small device can be implemented for CWDM systems in Photonic Integrated Circuits (PIC).
Bovine Cerebral Theileriosis: First Molecular Confirmed Report in Cross Bred Cattle Calf in India
Authors: Agrawal Vivek , Das G. , Singla L. D. , Shukla S. , Maharana B. R. , Jayraw A. K. , Shakya M. , Jatav G. P. 
Published: September 2021

Abstract
Bovine tropical theileriosis caused by Theileria annulata, is a serious constraint to Indian dairy industry with more fatal infections in exotic cattle and substantial losses to cross-bred and indigenous zebu cattle. The present communication is to place on record the first report of molecular based confirmed case of cerebral theileriosis caused by T. annulata coupled with its morphological detection, clinical manifestations, haematological alterations and therapeutic management in a cross bred cattle calf from India. After preparation of peripheral thin blood smear from cross bred cattle calf at the site of collection and fixation with methanol, blood sample brought to Department of Veterinary Parasitology, College of Veterinary Science and A.H, Jabalpur and stained by standard protocol for Giemsa staining. Genomic DNA was isolated from the collected blood sample using QIAamp® DNA blood mini kit following the manufacturer’s recommendations and PCR was performed. The cross bred cow calf revealed high rise in temperature (105.5°F), increased heart rate, labored breathing with seromucous nasal discharge, enlargement of prescapular lymph node and animal exhibited tonic clonic convulsions in response to any sudden noise. Giemsa stained thin blood smear revealed intraerythrocytic piroplasm and Koch blue bodies of T. annulata within the cytoplasm of lymphocytes. The species of Theileria was confirmed by molecular amplification of genomic DNA as T. annulata.
Down-Regulation of lncRNA XIST Ameliorates Lipoprotein(a) Induced Endothelial Progenitor Cell Damage via Modulating miR-126/PLK2 Axis
Authors: Zhang Xiaolei , Xu Guoying , Wang Shizhen , Chen Pei , Chen Shanshan 
Published: September 2021

Abstract
Background

Recent studies have discovered that lncRNAs regulate lipoprotein (LP) (a)-mediated endothelial progenitor cells (EPCs) damage through sponging miRNAs. However, the role of XIST in EPC remains unknown.
Method:

Firstly, LP(a)(100 ng/mL) was used to treat EPCs for 6 hours. Then, the apoptosis, proliferation, migration, adhesion, angiogenesis of EPCs were detected. Moreover, overexpression of XIST or miR-126 on EPCs were built. Mechanistically, bioinformatics database, dual-luciferase reporter assay and RIP were used to found the binding relationships between XIST and miR-126, miR-126 and PLK2.
Results

Presently, we found LP(a) treatment significantly induced apoptosis, attenuated the proliferation, migration, adhesion, angiogenesis of EPCs. While knocking down XIST or overexpression miR-126 significantly reversed LP(a) induced damage on EPCs. Moreover, forced overexpression of XIST partially offset the protective effects of overexpressing miR-126 on EPC. Mechanistically, through bioinformatics database (http://starbase.sysu.edu.cn/index.php), we found potential binding relationships between XIST and miR-126, miR-126 and PLK2. Furthermore, the dual-luciferase reporter assay and RIP experiment confirmed the targeted binding between them.
Conclusion

Collectively, the above results confirmed that down-regulating XIST improved LP(a)-induced EPC damage by regulating the miR-126/PLK2 axis, and the XIST/miR-126/PLK2 axis exerted an essential role in regulating EPC function.
Estimation of Optimum Alum Doses of Mountain Water for Water Supply Treatment in Hill Tribe Villages in Chiang Rai Province, Thailand
Authors: Sudsandee Suntorn , Patthanacheroen Natthathida 
Published: September 2021

Abstract
Hill tribe villages are located in mountainous and remote areas. Primary water supply and drinking water sources are mountain water from a small weir on the mountain. Most mountain waters found turbidity higher than 1 NTU, and water quality was unclean to use and drink. This research applied different concentrations of alum doses to observe turbidity reduction. Optimum alum does apply to reduce turbidity for mountain water samples from Hmong, Karen, Lahu, and Lisu for three seasons. The optimum alum dose is between 20 - 40 mg/l in rainy seasons and 10 – 40 mg/l in summer. The cold season was low optimum alum dose at 10 mg/l for all hill tribe villages. Therefore, alum coagulants can be used to treat the mountain water supply and drinking that can implement the main problem of mountain water in hill tribe village.
Visual Analysis of Carbon Emissions in Steel Industry Based on CiteSpace
Authors: Xu Desheng , Yang Ke , Duan Wei 
Published: September 2021

Abstract
This paper analyzes the research characteristics and development context of carbon emissions in the steel industry, which will provide reference for future carbon emissions research and practice in the steel industry in China. Based on the “Web of Science Core Collection” (hereinafter referred to as SCIE) database, this paper used CiteSpace software to make a bibliometric analysis of the literatures related to carbon emissions in the steel industry from 1991 to 2020 in terms of countries and regions, major publishing institutions, high-yield authors, keywords and time zone views. The results show that: 1) Scholars and research institutions in different countries and regions form a close cooperation network according to their geographical location;2) The research forces with China, the United States, the United Kingdom and Japan as the core have provided key research support and contributed major research results to the carbon emission field of the steel industry;3) Climate change, production technology and future scenario analysis are the three main research topics;4) In the future research stage, the comprehensive application of various disciplines such as technical and economic analysis, scenario analysis and environmental climatology will become the forefront of the research on carbon emissions in the steel industry.
Secondary Traumatic Stress in Iranian Midwives: Stimuli Factors, Outcomes and Risk Management
Authors: Hajiesmaello Maryam , Hajian Sepideh , Riazi Hedyeh , Majd Hamid Alavi , Yavarian⁵ Roya 
Published: September 2021

Abstract
Background: The present qualitative study was conducted to explain the experiences of secondary traumatic stress (STS) and its related factors in midwives working in maternity wards.Methods: Data were collected using semi-structured interviews with 11 midwives working in the maternity wards of hospitals in Urmia, Iran, through in-depth interviews with open-ended questions. Data were analyzed using the conventional content analysis approach.Results:The results of data analysis led to the extraction of three themes, seven main categories, and 18 subcategories. The first theme was “STS stimuli,” with the two categories of “Discriminatory approach to midwifery” and “The nature of the midwifery profession”. The second theme was “Traumatic outcomes”, which included the subcategories of “Psychological-emotional trauma”, “physical trauma” and “social trauma”. The third theme was “Risk management”, which had the two subcategories of “Reactive approach” and “Proactive approach”.Conclusions:The results showed that, in addition to the traumatic nature of events that midwives experience during work as the secondhand victims, factors such as governance-organizational structure, unbalanced distribution of power, and poor supportive laws undermine their professional role and provide conditions conducive to STS. Therefore, avoiding traumatic situations and scientific and skill self-empowerment were the most important strategies adopted by the midwives in this study to prevent risky situations and cope with the consequences of STS. The participation of midwifery stakeholders in policy-making and adopting supportive legislation in redefining the position and role of midwives can play a major role in reducing STS and sustaining their role and position in maternal care.
Production Risk and the Early Adoption of Alternatives to Antibiotics: Evidence From Poultry Farmers in China
Authors: Li Lingzhi , Zhou Li 
Published: September 2021

Abstract
Excessive or unreasonable use of agricultural chemicals has caused a wide range of negative effects on the environment and residents' health. It is urgent to promote the reduction of the use of agricultural chemicals. Taking the use of veterinary antibiotics (hereafter antibiotics) in broiler breeding as an example, based on the data of 380 contract farmers, this paper first investigated the effects of production risk on farmers' decision-making on the use of alternatives to antibiotics and the amount of antibiotics in the initial stage of alternatives entering into the market. The results show that: (1) the fluctuation of mortality in the lag period has no significant influence on the adoption of alternatives, and farmers are concerned about the absolute or average level of mortality in the lag period. (2) The mortality rate lagged three phases had a significant positive impact on the adoption of alternatives. On average, the mortality rate lagged three phases increased by 0.01, and the likelihood of farmers adopting substitutes in the early stage increased by 0.670%. (3) The production risk plays an important role in regulating the effects of alternatives. When using alternatives, the mortality rate of lagging three phases is higher, the higher the dosage of antibiotics and the lower the mortality rate in the early stage, suggesting that higher production risk would result in using alternatives for the purpose of reducing the production risk rather than reducing the use of antibiotics. Thus, to realize the effect of alternatives in reducing agricultural chemicals, the prerequisite is to improve the production risk management ability of farmers.
Under-five Mortality and Associated Factors among Children Born from 15-49 Years Old Mothers in Haramaya Town, Eastern Ethiopia
Authors: Ahmed Mohammed , Demena Melake , Teklemariam Zelalem , Desalew Assefa , Assefa Nega 
Published: September 2021

Abstract
Background: The global under-five mortality rate has dropped from almost 90 deaths per 1,000 live births in 1990 to 43 in 2015. The Ethiopian Mini Demographic Health Survey, 2019 shows 55 under-five deaths per 1,000 live births. In the eastern part of Ethiopia, evidence from the Kersa Health and Demographic Surveillance System in Kersa district of East Hararghe Zone, Oromia Region suggested the decline of under-five mortality rate from 131.8 per 1000 live births in 2008 to 77.4 per 1000 live births in 2013. The death rates still remain far from the Sustainable Development Goals’ target reduction to 25 or less per 1000 live births by 2030. However, the magnitude and determinants of under-five mortality is not studied in Haramaya town. Objective: To assess the under-five mortality rate and associated factors among children born during August 07, 2015- August 06, 2020 in Haramaya town, east Ethiopia by August 07–31/2020. Methodology: Quantitative cross-sectional population-based study was conducted on 391 pairs of 15-49 years old mothers and their live-born under-five children selected using systematic random sampling technique from Haramaya town to cmpare mortality between <=24 and >=25 mother’s age groups. Data were collected using interview-based questionnaire; double entered into EpiData 3.1; and then exported to statistical package for social sciences program version 20.0 for analysis. Binary logistic regression analysis (p-value <0.20) was performed to examine crude association of predictors with under-five mortality, and then multiple logistic regression analysis (p-value <0.05) to measure the statistical association. Results: The death of 28 out of 372 live births gave an under-five mortality rate of 75 per 1000 live births. Children born in households with less than 6 members had 7. 98 times higher odds of dying than those born in households with at least 6 members (AOR =7.98, 95% CI =1.59-40.17). Those children who did not feed colostrum were associated with 17.45 times increased risk of under-five deaths compared to colostrum-fed ones (AOR =17.45, 95% CI =6.54-46.55). Conclusion: The study suggests that 75 per 1000 live births die before celebrating their fifth birth day. Household size and colostrum feeding are the significantly associated factors.Recommendation: All concerned should inform the mothers the role of identified factors like household size and colostrum feeding in child survival.
Giant Solitary Fibrous Tumor of the Pancreas: A Case Report and Review of the Literature
Authors: peng junqiang , Liu Yanmin , Peng Qian , Dou Tingting , Fang Xiaochang , Yang Tiecheng , Wang Huaqiao , Yang Lijie , Li Xuanfei , Feng Maohui 
Published: September 2021

Abstract
Background: Solitary fibrous tumors (SFTs) originating from the pancreas are rare, only 23 cases have been reported so far. Here, we report the largest one, which has its unique treatment characteristics.Case report: A 42-year-old woman was admitted to the hospital with abdominal pain and abdominal mass, and the preoperative diagnosis was unclear. As the mass was rich in blood vessels, she underwent partial pancreatectomy after embolizing part of the blood vessels by preoperative intervention, which, at final pathology, showed spindle and oval cell proliferation and featured the presence of hemangiopericytoma-like blood. Immunohistochemistry showed cytoplasmic expression of CD34 and nuclear expression of STAT6, and mitotic activity was lower than 4 mitoses/10 high-power fields (HPFs). At the end, she was diagnosed with pancreatic SFT. The postoperative recovery was uneventful and she was alive and free of disease after 8 months.Conclusion: The diagnosis of SFT of the pancreas needs to be done very cautiously. Surgical treatment and postoperative follow-up are more reasonable methods at the moment.
CENPF Promotes Proliferation of Renal Cell Carcinoma In Vitro
Authors: Zhang Ji , Yuan Shushu , Zhu Hua , Chen Zhan , Liu Zhenmin , Ji Yuhang , Zheng Bing 
Published: September 2021

Abstract
Background: Metastasis and drug resistance are the main causes of renal cell carcinoma (RCC) mortality. Currently, there are still limited number of targeted therapies against advanced RCC. It is critical to develop new effective clinical biomarkers and drug targets in RCC. Several studies have shown that Centromere protein F (CENPF), a microtubule binding protein, promotes cancer progression in various types of cancer. The purpose of this study is to explore the role of CENPF in RCC.Materials and methods: Peripheral blood and corresponding tissue samples of 23 RCC patients and 23 normal physical examination patients who were treated in our hospital from 2018 to 2020 were collected, and the CENPF expression was detected by qRT-PCR, Western-blot and immunohistochemical methods. Down-regulate the expression of CENPF by siRNA transfection, and detect the proliferation of the corresponding RCC cells and the corresponding cell cycle.Results: According to TCGA data analysis, CENPF is highly expressed in RCC, and its expression level is significantly related to the overall survival and recurrence-free survival of RCC. In addition, high expression of CENPF was found in the tissues of RCC patients in our hospital. Knockdown of CENPF can significantly reduce the proliferation of RCC cells in in vitro experiments, and knockdown of CENPF can regulate the cell cycle by inhibiting the expression of cyclins such as CDK4, CDK6 and CyclinD1. Conclusion: CENPF can be used as an independent prognostic factor of RCC and regulate the proliferation ability and cell cycle of RCC cells. CENPF is a potential oncogene and prognostic marker in RCC.
Dynamic Changes in Prostate-Specific Antigen After Androgen Deprivation Therapy for Prostate Cancer are Strongly Associated with Biochemical Progression-Free Survival: A Multicenter Retrospective Analysis
Authors: Hu Mingqiu , Mao Yifeng , Zhang Kaizhong , Guan Chao , Wu Aiming 
Published: September 2021

Abstract
Objectives: The risk factors for prostate cancer to progress to castration-resistant prostate cancer after androgen deprivation treatment (ADT) are still not to be well defined. We conducted this investigation in an attempt to determine factors that predicted the prognosis in a series of patients with prostate cancer after ADT. Methods: We retrospectively analyzed the database of patients treated with androgen deprivation prostate cancer who were hospitalized in the Second Affiliated Hospital of Bengbu Medical College and Maoming People's Hospital from 2015.1.1 to 2020.12.30. PSA dynamic changes, including nadir PSA (nPSA), time to nadir PSA (TTN), were examined regularly. Cox risk proportional regression model was used for univariate and multivariate analysis; Kaplan-Meier survival curve and Log-rank test were used to compare and analyze differences in biochemical progression-free survival (bPFS) between groups. Results: During the follow-up with a median time of 43.5 months, a total of 163 men were included in the study. The median bPFS of the two groups with nPSA lower than 0.2ng/ml and ≥0.2ng/ml were 27.6 months and 13.5, respectively, with significant differences between the groups (Log-rank p<0.001); The median bPFS of the two groups with TTN ≥9 months and less than 9 were 27.8 months and 13.5 months, respectively, with significant differences between the groups (Log rank p<0.001). Conclusions: PSA dynamic changes after androgen deprivation treatment of prostate cancer can be used as prognostic indicators for bPFS. The lower the nadir PSA value and the longer the time to nadir, the longer the bPFS of patients with prostatic cancer after androgen deprivation treatment.
Assessment of Salivary Zink Level and its impact on Periodontal Health among Children and Adolescence with Sickle Cell Anemia
Authors: Hassan Rogyia Eltayeb , Kaddam Lamis AbdelGadir 
Published: September 2021

Abstract
Background: Sickle cell anemia (SCA) is the most common inherited disorder around the world. It affects red blood cells resulting in severe hemolysis and painful crisis with multi-organ damage. Sickle cell anemia patients showed an impaired antioxidant status due to a reduced antioxidant defense mechanism that depends indirectly on zinc micronutrient. Several studies revealed a low level of serum zinc among sickle patients. However, none of them investigates the impact of SCA on salivary zinc level. This study aims to measure zinc level in saliva and its influence on the periodontal health of Sudanese children with SCA in Khartoum state. Up to our knowledge, this the first study conducted to measure salivary Zink level and its impact on periodontal health among sickle patients Subjects and Methods: Cross-sectional study was conducted among children and adolescents aged 5-18 years old. Sixty individuals were involved, 30 with SCA compared to 30 healthy controls groups. An Atomic Absorption spectrophotometer quantified the salivary level of zinc. Periodontal examinations were assessed in SCA children using the periodontal community index.Results: The mean ages in the sickle cell anemic group were 10.37 ± 4.13 years old, while the mean ages of subjects in the control group were 9.37 ± 3.6 years (P.Value: 0.169). Salivary zinc level was significantly lower among SCA patients (P.Value <0.001) than in the healthy control group. None of the participants were diagnosed with periodontitis. The less salivary zinc level was significantly higher in SCA with standard pocket depth and no clinical attachment loss than patients diagnosed with gingivitis ( P. Value:0.025).Conclusions: Sickle patients have a low level of zinc in saliva, which may contribute to some manifestations of sickle cell disease and may make them more susceptible to periodontal disease in the future. We recommend conducting more research on oral and periodontal health among children affected with SCA to improve their quality of life.