bluuebunny/crossref_metadata_2025_split huggingface dataset:
Translation, Cross-Cultural Adaptation, and Psychometric Validation of the Chinese/Mandarin Cardiac Rehabilitation Barriers Scale (CRBS-C/M)
Authors: Liu Xia , Fowokan Adeleke , Grace Sherry L. , Ding Biao , Meng Shu , Chen Xiu , Xia Yinghua , Zhang Yaqing 
Published: June 2021

Objective. Cardiovascular diseases are among the leading causes of morbidity in China and around the world. Cardiac rehabilitation (CR) effectively mitigates this burden; however, utilization is low. CR barriers in China have not been well characterized; this study sought to translate, cross-culturally adapt, and psychometrically validate the CR Barriers Scale in Chinese/Mandarin (CRBS-C/M). Methods. Independent translations of the 21-item CRBS were conducted by two bilingual health professionals, followed by back-translation. A Delphi process was undertaken with five experts to consider the semantics and cross-cultural relevance of the items. Following finalization, 380 cardiac patients from 11 hospitals in Shanghai were administered a validation survey including the translated CRBS. Following exploratory and confirmatory factor analysis, internal consistency was assessed. Validity was tested through assessing the association of the CRBS-C/M with the CR Information Awareness Questionnaire. Results. Items were refined and finalized. Factor analysis of CRBS-C/M (

Kaiser

Meyer

Olkin
=
0.867

, Bartlett’s test

p
<
0.001

) revealed five factors: perceived CR need, external logistical factors, time conflicts, program and health system-level factors, and comorbidities/lack of vitality; Cronbach’s alpha (

α

) of the subscales ranged from 0.67 to 0.82. The mean total CRBS score was significantly lower in patients who participated in CR compared with those who did not, demonstrating criterion validity (

2.35
±
0.71

vs.

3.08
±
0.55

;

p
<
0.001

). Construct validity was supported by the significant associations between total CRBS scores and CR awareness, sex, living situation, city size, income, diagnosis/procedure, disease severity, and several risk factors (all

p
<
0.05

). Conclusions. CRBS-C/M is reliable and valid, so barriers can be identified and mitigated in Mandarin-speaking patients.
Effect of 70% Ethanol Extract and its Solvent Fractions of Artemisia afra (Jacq. Ex Willd.) against Pentylenetetrazole-Induced Seizure in Mice
Authors: Kediso Teketel Eristu , Tolessa Tesfaye , Getachew Fikirte , Makonnen Eyasu , Seifu Daniel 
Published: June 2021

Introduction. Artemisia afra (Jacq. ex Willd.), commonly called African wormwood, is a highly aromatic perennial herb and a well-known medicinal plant, claimed to be effective and safe in the treatment of epilepsy. The whole-plant extract is traditionally used as an antiepileptic agent in Ethiopia. Aim of the Study. The aim of this study was, therefore, to evaluate the anticonvulsant effect of the hydroethanolic extract and solvent fractions of A. afra whole part in mice. Materials and Methods. The effects of A. afra hydroethanolic extract and its solvent fractions were evaluated against pentylenetetrazole- (PTZ-) induced convulsions in mice. The onset and duration of PTZ-induced convulsions were determined with hydroethanolic A. afra extract and its solvent fractions. Data were analyzed using a one-way analysis of variance (ANOVA) followed by post hoc Tukey’s multiple comparisons test.

p
<
0.05

was considered statistically significant. Results. The hydroethanolic extract of A. afra, with all the three doses of 250, 500, and 1000 mg/kg, showed a significant delay (504.833 ± 62.835

∗

s;

p
<

0.05

∗

; 551.833 ± 47.69

∗
∗

s;

p
<

0.01

∗
∗

; and 808.333 ± 64.8

∗
∗
∗

s;

p
<

0.001

∗
∗
∗

, respectively) in the mean onset of convulsion and a decrease (17.000 ± 1.88

∗
∗
∗

s,

p
<

0.05

∗

; 13.000 ± 1.8

∗
∗

s,

p
<

0.01

∗
∗

; and 7.833 ± 1.07

∗
∗
∗

s,

p
<
0.001

, respectively) in the mean duration of convulsion against PTZ-induced convulsion in a dose-dependent manner compared to the control (92.833 ± 13.006 s; 34.167 ± 3.683 s), and its anticonvulsant activity was significantly less compared to that of diazepam (1001.167 ± 68.430 s; 4.500 ± 0.619 s). The solvent fractions, however, did not show anticonvulsant activity against PTZ-induced convulsion. Conclusion. Crude extract of A. afra has an anticonvulsant effect in mice. This might be attributed to the synergistic effects of two or more active ingredients present in the herb.
Vulnerabilidade às mudanças climáticas e o caso dos pescadores artesanais de Pontal do Paraná: entre o desconhecimento da questão climática a falta de políticas públicas adaptativas
Authors: Minari Nathália Bassoli , Carmo Aline Borges do 
Published: June 2021

O presente estudo verificou a condição de vulnerabilidade às mudanças climáticas dos pescadores artesanais de Pontal do Paraná em relação a dois aspectos: a conhecimento sobre a temática, e a existência de políticas públicas adaptativas de cunho socioambiental destinadas especificamente a esta população tradicional. De modo a abordar a questão, a pesquisa apresenta resultados provenientes de entrevistas e questionários aplicados a 28 pescadores, bem como o resultado de entrevistas aplicadas aos representantes do Fórum Paranaense de Mudanças Climáticas Globais e do Programa BioClima Paraná, ambos inseridos na Secretaria Estadual do Meio Ambiente e Recursos Hídricos do Paraná (SEMA). Foi possível observar segundo a análise dos discursos dos pescadores que o conhecimento que estes apresentam sobre mudanças climáticas é incipiente, e que, por vezes, o tema é confundido com aspectos meteorológicos. As políticas públicas existentes na região não apresentam especificidade com os grupos vulneráveis do estudo. De tal forma, apresenta-se aqui um caso de vulnerabilidade sócio-ambiental quanto aos impactos das mudanças climáticas.
Creating Cultural Capital: The Education of Jewish Females at the Alliance Israélite Universelle (AIU) School for Girls in the City of Tunis, 1882–1914
Authors: Land Joy A. 
Published: June 2021

Abstract
Based on rarely viewed images from the fin de siècle, this article will contribute to the burgeoning field of Jewish women in the world of Islam. At the Alliance Israélite Universelle (AIU) School for Girls in the city of Tunis, 1882–1914, after a seven-year course of study, Jewish and non-Jewish girls acquired certification of their academic or vocational skills through a certificate or diploma of couture. Such credentials, according to Bourdieu (1986), constitute “cultural capital.” Furthermore, “cultural capital … is convertible … into economic capital and may be institutionalized in the forms of educational qualifications.” A young woman could create cultural capital and transform it into economic capital through employment. Reading the sources, the influence of the Tunisian Muslim woman on the Jewess becomes apparent. Moreover, cultural capital could afford the Jewish female wage earner increased economic independence and social mobility, as she journeyed on the road to modernity.
Reading Josephus’ “Prophetic” Inspiration in the Cave of Jotapata (J.W. 3.351–354) in a Roman Context
Authors: Glas J. E. (Eelco) 
Published: June 2021

Abstract
This article offers a literary analysis of the famous episode in Judean War 3.351–354, in which Josephus suddenly recalls his “nightly dreams.” It takes up the question of how Josephus characterizes himself in this episode in consideration of an elite audience located in Rome steeped in Greco-Roman learning. In explaining this episode, scholars have put special emphasis on parallels with discourses of Judean prophecy and biblical prophets, such as Jeremiah and Daniel. The hypothesis that Josephus consciously presents himself as a prophet has found widespread acceptance and grown to become almost undisputable since the 1970s. In addition to challenging the view that Josephus explicitly and deliberately presents himself as a biblical prophet, the present contribution develops an interpretation that considers the historiographical outlook of the whole War as a military-political composition imbued with classicizing features.
The Significance of the Divine Torah in Ptolemaic Egypt in Documentary and Literary Sources from the Third and Second Centuries BCE
Authors: Altmann Peter 
Published: June 2021

Abstract
This essay analyzes the Torah’s role in Judean communities from Ptolemaic Egypt in order to evaluate the significance of the Judean claim of divine origins for their law in relation to the conceptual or functional nature of this law. An introductory step explores the nature of the Judean communities in Egypt under the Ptolemies. The essay then moves to consider the nature of judicial practice in Ptolemaic Egypt, especially among Judean communities, where scholars have asserted overlap with the written Greek Torah in the interpretation of legal records. Given the largely negative finds from papyri documents concerning practical judicial conceptions, the discussion turns to depictions of Torah in the Letter of Aristeas and other Hellenistic-Judean literature. The argument demonstrates that direct references to the Torah conceive of its importance in philosophical terms and group affiliation rather than judicial categories, even when the conception of God as a divine legislator emerges.
Protecting Privacy and Transforming COVID-19 Case Surveillance Datasets for Public Use
Authors: Lee Brian , Dupervil Brandi , Deputy Nicholas P. , Duck Wil , Soroka Stephen , Bottichio Lyndsay , Silk Benjamin , Price Jason , Sweeney Patricia , Fuld Jennifer , Weber J. Todd , Pollock Dan 
Published: June 2021

Objectives Federal open-data initiatives that promote increased sharing of federally collected data are important for transparency, data quality, trust, and relationships with the public and state, tribal, local, and territorial partners. These initiatives advance understanding of health conditions and diseases by providing data to researchers, scientists, and policymakers for analysis, collaboration, and use outside the Centers for Disease Control and Prevention (CDC), particularly for emerging conditions such as COVID-19, for which data needs are constantly evolving. Since the beginning of the pandemic, CDC has collected person-level, de-identified data from jurisdictions and currently has more than 8 million records. We describe how CDC designed and produces 2 de-identified public datasets from these collected data. Methods We included data elements based on usefulness, public request, and privacy implications; we suppressed some field values to reduce the risk of re-identification and exposure of confidential information. We created datasets and verified them for privacy and confidentiality by using data management platform analytic tools and R scripts. Results Unrestricted data are available to the public through Data.CDC.gov, and restricted data, with additional fields, are available with a data-use agreement through a private repository on GitHub.com. Practice Implications Enriched understanding of the available public data, the methods used to create these data, and the algorithms used to protect the privacy of de-identified people allow for improved data use. Automating data-generation procedures improves the volume and timeliness of sharing data.
The effectiveness of nurse-led self-management support program for people with chronic kidney disease stage 3-4 (CKD-NLSM): Study protocol for a randomized controlled trial
Authors: Ayat Ali Al Sawad , Lim Soo Kun , Tang Li Yoong , Rashid Aneesa Abdul , Chew Boon-How 
Published: June 2021

The complexity of chronic kidney disease (CKD) and its treatments have made self-management behaviors inevitably challenging. However, supplementing education with self-management skills may improve numerous health outcomes in people with nondialysis CKD. This study protocol describes a randomized controlled trial (RCT) aimed to evaluate the effects of a nurse-led self-management support program as an intervention for kidney disease knowledge and CKD self-management behaviors among people with pre-dialysis CKD. In Phase 1, people with CKD stage 3–4 and their family members are involved in co-designing, development and pilot testing of a theory-based self-management intervention. In Phase 2, we perform a cross-cultural adaptation of the Kidney Disease Knowledge Survey, CKD Self-Management and Self-efficacy for Managing Chronic Disease questionnaires. In Phase 3, a parallel RCT will be conducted to evaluate the intervention where 154 participants with CKD stage 3–4 will be randomly assigned to either the intervention ( n = 77) or control group ( n = 77). The intervention group will receive 6-week self-management program from a nurse-coach in addition to standard usual care, while the control group will receive only standard usual care. Outcome measures include kidney disease knowledge, CKD self-management behavior, self-efficacy, quality of life, blood pressure control and adherence to CKD diet as indicated by 24-h urine urea nitrogen, 24-h urine sodium and net endogenous acid production. Data will be collected at baseline and 12-week post-baseline. The between- and within-group intervention effects will be estimated using the Generalized Estimating Equations. The self-management intervention offers strategies to delay CKD progression and to encourage motivation to better self-manage at home. This study integrates self-management education and psychosocial support with culturally relevant scenarios, and evaluates important self-reported and objective outcomes. Clinical Trials Registration: www.ClinicalTrials.gov , identifier: NCT03974646.
Increasing Participation in Psychological Science by Using Course-Based Research Projects: Testing Theory, Using Open-Science Practices, and Professionally Presenting Research
Authors: Frankowski Scott D. 
Published: June 2021

Introduction: Undergraduate research experiences prepare students for graduate training or employment. Statement of problem: At many teaching-intensive universities, there is a greater demand for research experiences than there are independent study opportunities. Students from typically underrepresented backgrounds may also be unaware of a department’s undergraduate research pipeline of independent study, honor’s theses, and internal research funding. Literature review: Course-based research contributes to diversity and inclusivity in access to undergraduate research experiences, especially at teaching-intensive universities. Course-based research is often integrated into methods courses, but not content courses. Teaching implications: I present practical ways to integrate research projects into courses. I stress the importance of testing theory, teaching open-science practices, and providing opportunities for students to present professionally. I also provide examples of implementing group research projects in content courses. Conclusion: Implementing course-based research projects, especially at teaching-intensive universities, can expand access to psychological science by providing valuable research opportunities for many students. Instructors can also benefit by intertwining their teaching, mentoring, and research goals. Future research should focus on experimentally testing learning outcomes.
The effects of olive oil and cholesterol enriched diets on aortic fatty streak development and lipid peroxidation in rabbits
Authors: Paknahad Zamzam , Moosavian Seyedeh Parisa , Mahdavi Reza , Rajabi Parvin 
Published: June 2021

Background and aim: High plasma cholesterol levels, mainly low-density lipoprotein-cholesterol (LDL) is a widely recognized major risk factor for coronary heart disease (CHD). According to epidemiologic studies’ findings, people from the Mediterranean countries have lower CHD rates than other countries; in these countries the usual diet is high in olive oil. The present study compares the effects of a cholesterol-enriched diet with or without adding olive oil on serum lipoproteins, lipid peroxidation, and atherosclerosis development. Methods: Twenty Dutch male rabbits were categorized into four groups (one group as control, and others as experimental). They received one of control (CON), olive oil-rich (OIL), cholesterol-rich (CHOL), and cholesterol + olive oil (COIL) diet for 12 weeks. Fasting blood samples from the heart were collected at the beginning and the end of the experimental period. Results: Means of serum lipids were not significantly different at the beginning of the experimental period. After the intervention, significant differences were shown in total cholesterol (TC) (CON: 27.75 ± 4.83, OIL: 19.75 ± 2.62, CHOL: 1757.20 ± 149.62, COIL: 2906.40 ± 421.01; P < 0.001), high-density lipoprotein-cholesterol (HDL-C) (CON: 16 ± 1.47, OIL: 10.25 ± 1.70, CHOL: 22.2 ± 3.83, COIL: 28.60 ± 6.27; P = 0.04), triglyceride (CON: 65 ± 12.21, OIL: 71.75 ± 6.23, CHOL: 244.2 ± 44.45, COIL: 775.6 ± 105.07; P < 0.001), and MDA between groups (CON: 0.57 ± 0.10, OIL: 0.63 ± 0.15, CHOL: 5.62 ± 0.18, COIL: 2.06 ± 0.64; P < 0.001). The comparison of CHOL and the COIL groups showed a higher mean of malondialdehyde (MDA) in group CHOL (4.47 ± 0.28 vs 1.1 ± 0.6; P < 0.001). Aortic lesion was not observed in CON and OIL groups. Aortic lesion degree was significantly lower in the COIL group compared to the CHOL (2.4 ± 0.6 vs 3.66 ± 0.33; P = 0.02). Conclusions: These findings showed the preventive effect of olive oil on atherosclerosis development. However, it is independent of the plasma lipoprotein effect, and olive oil probably acts on arteries directly.
Sorafenib plus partial splenic embolism for treatment of hepatocellular carcinoma Barcelona stage C combined with hypersplenism: a case series
Authors: Zeng Jianting , Wang Chunmei , Wang Yu , Luo Zhenhua , Zhang Yanlin , Luo Xianzhang 
Published: June 2021

Background Sorafenib is mainly used to treat patients with hepatocellular carcinoma (HCC) Barcelona Clinic Liver Cancer (BCLC) stage C, many of whom also have severe cirrhosis. However, hypersplenism and digestive tract hemorrhage are common complications of cirrhosis, which increase the risk and difficulty of treatment. Methods Nineteen patients with HCC BCLC stage C with hypersplenism were treated with sorafenib plus partial splenic embolism at Chongqing University Cancer Hospital, Chongqing, China, between January 2015 and June 2018. We analyzed the therapeutic effect and clinical safety of this treatment in these patients. Result Hypersplenism was rectified in all patients. The incidence rates of hemorrhage and myelosuppression were 0%, and the mean survival time was 11.2 months. Conclusion Sorafenib plus partial splenic embolism could relieve hypersplenism and prolong survival in patients with BCLC stage C HCC.
Condom Decision Making Among Latino and Black Adolescent Males: Social Neurobiological and Paternal Influences
Authors: Guilamo-Ramos Vincent , Benzekri Adam , Thimm-Kaiser Marco , Rivera Margarita , Fuller Taleria R. , Warner Lee , Koumans Emilia H. A. 
Published: June 2021

Purpose: We explored mechanisms of paternal influence associated with adolescent male condom decision making and behavior within an integrated framework of social neurobiological and behavioral theories of condom use. Method: Self-administered surveys from Latino and Black adolescent males aged 15–19 years ( n = 191) and their fathers were obtained. Dyads were recruited using area sampling methodology. Analyses included multivariable logistic and ordinary least squares regression examining direct and indirect associations of adolescent decision-analytic and paternal influence factors with adolescent condomless sex in the past 3 months. Results: Notions of masculinity, low-risk perception, partner approval of, and self-efficacy for condomless sex were associated with engaging in unprotected sex. Adolescent males reported reduced odds of engaging in condomless sex when indicating greater levels of father–son communication, relationship satisfaction, and paternal monitoring. Conclusion: Father-based interventions grounded in integrated theoretical frameworks of behavioral decision making and neuroscience have the potential to promote condom use among adolescent males.
Electronic Cigarette Cessation in Youth and Young Adults: A Case Series
Authors: Sikka Gautam , Oluyinka MopeninuJesu , Schreiber Raiza , Galiatsatos Panagis 
Published: June 2021

Introduction: Electronic cigarette (e-cigarette) usage use has increased exponentially, especially in youth and young adults. For many, the usage of these products results in a severe addiction, one that is difficult to discontinue. Further, e-cigarette cessation is challenging as there are no specific guidelines directing such medical management for patients and their respective clinicians. Here, we report a case series of patients who we are attempting to wean from e-cigarettes with medical guidance. Methods: Six patients who self-reported daily e-cigarette usage and were enrolled in our Tobacco Treatment Clinic (TTC) were followed for 12-months. An inventory of the e-cigarette product and usage was captured, along with responses to identify when the patients experienced majority of their cravings. Co-morbidities, if present, were documented. Documentation of interventions, counseling with or without pharmacological therapies, were captured. Primary outcome was cessation at 6-months. Results: The 6 patients enrolled in clinic ranged in age from 17 to 31 years, with 4 of the patients identifying as males and 2 as females. Patients were using e-cigarettes for 1 to 6 years prior to enrolling into the TTC. As for interventions, all patients received counseling and pharmacological interventions in the form of nicotine replacement therapies (NRTs). Three of the 6 patients were weaned off e-cigarettes by 6-months, with a fourth patient weaned off at the 8-month mark. Variables identified as barriers to cessation included non-compliance with medical regimen and peer influence. Discussion: Here we present a case series of attempting to wean persons from electronic cigarettes use. Given the lack of international guidelines in e-cigarette addiction management, we believe this case series will be of value for clinicians and their patients. Further studies are warranted to help patients with e-cigarette addiction in their attempt at cessation.
Prognostic Nomogram for Patients With Pancreatic Ductal Adenocarcinoma of Pancreatic Head After Pancreaticoduodenectomy
Authors: Zhuang Hongkai , Zhou Zixuan , Ma Zuyi , Huang Shanzhou , Gong Yuanfeng , Li Zhenchong , Liu Chunsheng , Wang Shujie , Chen Bo , Zhang Chuanzhao , Hou Baohua 
Published: June 2021

Background: The prognosis of patients with pancreatic ductal adenocarcinoma (PDAC) of pancreatic head remains poor, even after potentially curative R0 resection. The aim of this study was to develop an accurate model to predict patients’ prognosis for PDAC of pancreatic head following pancreaticoduodenectomy. Methods: We retrospectively reviewed 112 patients with PDAC of pancreatic head after pancreaticoduodenectomy in Guangdong Provincial People’s Hospital between 2014 and 2018. Results: Five prognostic factors were identified using univariate Cox regression analysis, including age, histologic grade, American Joint Committee on Cancer (AJCC) Stage 8th, total bilirubin (TBIL), CA19-9. Using all subset analysis and multivariate Cox regression analysis, we developed a nomogram consisted of age, AJCC Stage 8th, perineural invasion, TBIL, and CA19-9, which had higher C-indexes for OS (0.73) and RFS (0.69) compared with AJCC Stage 8th alone (OS: 0.66; RFS: 0.67). The area under the curve (AUC) values of the receiver operating characteristic (ROC) curve for the nomogram for OS and RFS were significantly higher than other single parameter, which are AJCC Stage 8th, age, perineural invasion, TBIL, and CA19-9. Importantly, our nomogram displayed higher C-index for OS than previous reported models, indicating a better predictive value of our model. Conclusions: A simple and practical nomogram for patient prognosis in PDAC of pancreatic head following pancreaticoduodenectomy was established, which shows satisfactory predictive efficacy and deserves further evaluation in the future.