bluuebunny/crossref_metadata_2025_split huggingface dataset:
Arts Engagement Facilitated by Artists With Individuals With Life-limiting Illness: An Integrative Review of the Literature
Authors: Lee Jennifer Baxley , McIlfatrick Sonja , Fitzpatrick Lisa 
Published: January 2021

Abstract
BackgroundLiving with life-limiting illness significantly impacts quality of life. A growing body of evidence suggests that arts engagement, facilitated by artists, promotes a sense of well-being and connection with others. However, much of the evidence is drawn from the use of the arts in broad health contexts or from creative arts therapies’ literature. This review aimed to systematically identify and synthesize existing evidence in order to reveal key knowledge gaps and to inform future research and practice. MethodsAn integrative review of the literature was conducted using a pre-defined, comprehensive search strategy. Databases searched included: PubMed inclusive of MEDLINE, CINAHL, PsycINFO, Scopus, Web of Science, and Embase. Search terms included variations on visual arts, literary arts, and performing arts; service users or patients; and palliative care or end-of-life care. The quality and rigor of articles were scored using Hawker and colleagues’ tool designed to systematically appraise disparate studies. Synthesis was conducted using a constant comparison method as outlined in the integrative review framework.ResultsEight reviewed studies explored literary, performing, and visual arts engagement in residential hospice, day hospice, and hospitals in England, the United States, France, and Canada. Seven of eight studies used qualitative methods and one study engaged in mixed methods. Patient perspectives were most commonly represented followed by health care professionals and family members. Creative writing, music, and visual art were predominant modalities whilst dance and theatre were underrepresented. Themes identified across studies associated arts engagement with 1) a sense of well-being, 2) a newly discovered, or re-framed, sense of self, 3) connection with others, 4) challenges associated with practice. ConclusionThis review synthesized current evidence and key knowledge gaps regarding artists' facilitation of arts engagement in palliative and end-of-life (EOL) care. It serves as a starting point in the consideration of next steps in standardizing professional practice and preparation for artists working in palliative and EOL care settings specifically. Recommendations for future research include exploring the value of collaboration between artists and palliative care teams when engaging with individuals living with life-limiting illness.
Before The 2020 Pandemic: An Observational Study Exploring Public Knowledge, Attitudes, Plans, and Preferences Towards Death and End of Life Care in Wales
Authors: Islam Ishrat , Nelson Annmarie , Longo Mirella , Byrne Anthony 
Published: January 2021

Abstract
Background: Understanding public attitudes towards death and dying is important to inform public policies around End of Life Care (EoLC). We studied the public attitudes towards death and dying in Wales.Methods: An online survey was conducted in 2018. Social media and the HealthWiseWales platform were used to recruit participants. Data were analysed using descriptive statistics and thematic analysis.Results: 2,210 people participated. Loss of independence (84%), manner of death, and leaving their beloved behind were the biggest fears around death and dying. In terms of EoLC, participants sought timely access to care (84%) and being surrounded by loved ones (62%). Being at home was less of a priority (24%). Only 50% were familiar with Advance Care Planning (ACP). A lack of standard procedures as well as of support for the execution of plans and the ability to revisit those plans hindered uptake. The taboo around death conversations, the lack of opportunities and skills to initiate discussion, and personal fear and discomfort inhibited talking bout death and dying. 72% felt that we do not talk enough about death and dying and advocated normalising talking by demystifying death with a positive approach. Health professionals can initiate and support this conversation, but this depended on communication skills and manageable workload pressure. Participants encouraged a public health approach and endorsed the use of: a) social media and other public platforms, b) formal education, c) formal and legal actions, and d) signposting and access to information. Conclusions: People are ready to talk about death and dying and COVID-19 has increased awareness. A combination of top-down and bottom-up initiatives across levels and settings can increase awareness, knowledge, and service-utilisation - drivers to support health professionals and people towards shared decisions which align with people’s end of life wishes and preferences.
Sociodemographic Factors Associated With Knowledge of Type 2 Diabetes in Rural Tamil Nadu, India: a Cross-sectional Study
Authors: MacDonald Hana , Papadopoulos Andrew , Dewey Cate , Humphries Sally , Dodd Warren , Patel Kirit , Little Matthew 
Published: January 2021

Abstract
Background: This study aimed to investigate the overall awareness of type 2 diabetes as well as how sociodemographic factors influence diabetes knowledge. With India having the second highest prevalence of diabetes globally, it is increasingly important to assess how diabetes can be addressed in rural Indian populations. Methods: Systematic random sampling was used to gather study participants in 17 villages within the Krishnagiri district of Tamil Nadu, India. Associations between sociodemographic factors and composite diabetes knowledge score were assessed using a multinomial logistic gllamm model.Results: A total of 753 individuals participated in the study. Overall knowledge on diabetes was low, with 66% of individuals having no knowledge regarding diabetes. Achieving a moderate knowledge score was significantly positively associated with education, wealth, participation in MGNREGA (Mahatma Gandhi National Rural Employment Guarantee Act), and business ownership as a source of income. Achieving a good knowledge score was significantly positively associated with education, wealth, rurality, participation in MGNREGA, business ownership as a source of income, as well as frequency of healthcare typically received. Rurality was significantly negatively associated [Relative Risk Ratio (95% CI)] with both moderate knowledge score [0.34 (0.19, 0.59)], and good knowledge score [0.43 (0.24, 0.74)]. The strongest predictor of having a good knowledge score was having a high school graduate or post-secondary education [11.07 (4.44, 27.61)]. Enrolment in MGNREGA employment was the strongest predictor for having a moderate knowledge score [3.27 (1.93, 5.54)], as well as strongly associated with having a good knowledge score [2.39 (1.31, 4.36)].Conclusion: The low awareness of diabetes seen in this study raises serious concerns for public health in India. Public health efforts must prioritize health equity to lessen the impacts of diabetes in rural populations, where individuals face systemic barriers to receiving prevention and treatment for conditions such as diabetes.
Transient Atypical Lymphoplasmacytic Proliferation in Endometrium Associated With Pyometra: a Case Report
Authors: Otani Tomoyuki , Murakami Kosuke , Kimura Masatomo , Matsuki Mitsuru , Satou Takao , Matsumura Noriomi , Ito Akihiko 
Published: January 2021

Abstract
Background Plasmablastic lymphoma is a mature B-cell neoplasm with plasmablastic differentiation, often associated with human immunodeficiency virus (HIV) infection and other forms of immunosuppression. Although it is usually an aggressive disease, spontaneous regression has been seen in a few cases. Plasmablastic lymphoma in the uterus is rare. Here we report a case of atypical lymphoplasmacytic proliferation resembling plasmablastic lymphoma associated with pyometra that disappeared completely as the pyometra resolved. Case presentation A 76-year-old HIV-negative woman presented with abnormal vaginal bleeding. Ultrasound and MRI findings were consistent with pyometra diagnosis. Endometrial biopsy revealed large plasmablastoid cells with abundant cytoplasms and prominent nucleoli proliferating in the endometrium. Immunohistochemistry showed that large cells stained positive for CD138, CD79a, and MUM1, and negative for CD20, PAX5, CD3, and CD5. Ki67 labelled at least 80% of the large cells. Epstein–Barr virus was detected in a small number of cells. The histological picture was highly indicative of lymphoma, especially plasmablastic lymphoma, though the clinical context was unusual. As the pyometra was treated and resolved, the intrauterine abnormality disappeared completely. The patient has been well after 16 months with no sign of recurrent disease. Conclusions This case underscores the sometimes blurry distinction between benign inflammation and lymphomas.
Reach, Adoption and Sustainability of a Mobile Clinical Decision Support Tool Paired With a National Quality Improvement Project Targeting Emergency Department Febrile Infant Management
Authors: Kerns Ellen K , McCulloh Russell , Dai Hongying 
Published: January 2021

Abstract
Background: Electronic clinical decision support (ECDS) tools are often developed within quality improvement (QI) projects to increase adherence with the latest clinical practice guidelines (CPGs).However, scalability and sustainability of ECDS beyond the time and location of their associated project are very limited. Deploying ECDS using a mobile app (mECDS) has shown the potential to be a viable method of overcoming these limitations. However, it is unclear what pattern the spread of uptake and use of such a tool might follow.Methods: In 2016, our team released a freely available mECDS as part of a national multi-site project entitled Reducing Variation in Infant Sepsis Evaluation (REVISE). For this study, we evaluated trends in weekly mECDS usage measures defined as 1) REVISE metric related screen views (MetricHits), 2) unique designated market areas (DMA) where the mECDS was used (Unique DMAs), 3) density of use or MetricHits/Unique DMAs (HitsPerDMA). Linear regressions were performed to examine the app usage trends measures across three time periods (during REVISE, 1-year post, 2-year post). Separate regression analyses were performed among DMAs that contained a REVISE site and those that did not. The number of REVISE sites in the DMA, the number of children’s hospitals in the DMA, DMA population, and season were also evaluated as confounding factors.Results: Strong growth in the number of unique DMAs and MetricHits occurred during the period of 1-year post the REVISE project. The overall usage continued to be relatively stable during the period of 2-years post. HitsPerDMA had stronger growth in DMAs with a REVISE site than those without. MetricHits were higher in DMAs with a larger population, more REVISE sites, and more children’s hospitals. There were also more MetricHits in the summer than in the winter months. Conclusions: Both temporal and spatial increases in mECDS app usage were found as evidence of a contagion method of spread. Other confounding factors may also play a role in app reach, adoption, and sustainability. Further research is needed to determine the factors driving passive diffusion and its impact on clinical practice and patient outcomes.
Food Marketing, Eating Behaviors and Gender Among Children and Adolescents: A Scoping Review
Authors: Castronuovo Luciana , Guarnieri Leila , Tiscornia Victoria , Allemandi Lorena 
Published: January 2021

Abstract
Background Pervasive marketing of unhealthy foods is one of the main drivers behind the global epidemic of childhood and adolescent overweight and obesity. Sex and gender differences come into play in the design of and responses to these marketing strategies, contributing to the perpetuation of stereotyped behavior and generating disparities in food choices and health among boys and girls. The purpose of this paper is to review the current the literature regarding gender differences in food marketing design and perception among children and adolescents to facilitate evidence-based policy dialogues to address gender-based health disparities in NCD prevention.Methods Scoping review of articles published in scientific journals in English and Spanish from 2003 on that addressed the influence of food marketing on eating behaviors among children and adolescents including a gender perspective. The methodological quality of each article was assessed following criteria specific to each study design.Results A total of 40 articles (42 studies) were included in the review. 19 were experimental and 23 had descriptive, cross-sectional designs. 22 studies were found to have low methodological quality, while 11 and 9 were of medium and high quality, respectively. 24 studies found gender-based differences with regards to the effect of food marketing on food intake, food choice and preferences, responses to specific marketing strategies and techniques, perceptions and attitudes towards food marketing and the need for its regulation, and advertising content and exposure. Conclusions The evidence suggests that food marketing has a similar impact on the consumption of unhealthy foods on both boys and girls, but boys were found to be exposed to food advertising more intensively and their preferences to be more affected by this exposure, in line with a mostly male-dominant advertising content. Limitations of these studies include taking gender as an unproblematic construct equivalent to biological sex and the lack of studies focused on developing countries. As gender is a cross-sectional dimension that interacts with other factors driving health disparities, an integrated gender perspective is needed in order to develop effective, evidence-based policies to control food marketing and tackle the childhood overweight pandemic.
What Factors Are Associated With Elbow Stiffness After Operation of Terrible Triad Injury？
Authors: Zhu Jian , Deng Xiangtian , Cheng Xiaodong , Tan Zhanchao , Hu Hongzhi , Zhang Yingze 
Published: January 2021

Abstract
Background: The elbow stiffness is a common complication after operation of terrible triad injury (TTI) and significantly impair the patients’ activities of daily living, while the risk factors have yet to be clearly identified. The goal of this study was to examine the patient-related, injury-related, and treatment-related factors for elbow stiffness after operation of terrible triad injury.Methods: Between January 2013 and December 2019, 71 patients at two tertiary-care referral centers underwent operation of terrible triad injury were respectively reviewed. Range of motion (ROM), Mayo elbow performance scores (MEPS), Broberg-Morrey scores were used for functional evaluation. According to the ROM, the patients were categorized into stiffness group and non-stiffness group. The former had < 100° of extension-flexion ROM and the latter had > 100°. The patient-related, injury-related, and treatment-related factors were extracted from the medial records. The multivariant logistic regression were performed to identify the independent factors.Result: At a mean follow-up of 35.9 months (12-68 months),13 patients were classified into the stiffness group and 58 patients in the non-stiffness group. The stiffness group had significant worse functional scores compared to the non-stiffness group. Patients in the stiffness group were more likely to be Mason type III fracture, high-energy injuries, to have longer time between injury and surgery, ipsilateral upper limb injuries, and other fractures in body. However, multivariant logistic regression analysis revealed that time between injury and surgery > seven days, concurrent ipsilateral upper limb injuries and high-energy injury were independent factors that increased the risk of elbow stiffness after operation of terrible triad injury.Conclusions: The patients underwent operation for terrible triad injury should be informed the probability of elbow stiffness when concurred ipsilateral upper limb injuries and operations should be conducted without delay. Knowledge of these risk factors will be helpful for guiding prophylaxis and early intervention in patients with high risk of elbow stiffness after operation of terrible triad injury.
Correlation Between Weight Bearing Asymmetry and Bone Mineral Density in Patients With Bilateral Knee Osteoarthritis
Authors: Nishizawa Kohei , Harato Kengo , Morishige Yutaro , Kobayashi Shu , Niki Yasuo , Nagura Takeo 
Published: January 2021

Abstract
Background: Although unloading of the joint is related to reduction of the local bone mineral density (BMD), little attention had been paid to the relationship between loading asymmetry and side-to-side difference of BMD in patients with bilateral knee osteoarthritis (OA). The aim of the present study was to evaluate and clarify the relationship between gait parameters and bone mineral density in those patients.Methods: A total of 36 knees in eighteen patients (mean age = 73.7 ± 6.3 years, mean body mass index = 26.7 ± 3.8 kg/m2) with bilateral medial knee OA were enrolled in the present study. All subjects performed relaxed standing and level walking at our gait laboratory after informed consent was obtained. First, ground reaction force was calculated on bilateral knees during standing. The knees in each patient were divided into Higher and Lower force side for the definition of dominant side limb. Second, gait parameters in each subject were obtained. To analyze the factors that affect the weight bearing distribution in both limbs, clinical data and biomechanical parameters were compared between knees. Clinical data included radiographic OA grade, femorotibial angle and BMD at the bilateral femoral neck.Results: Knees on Higher force side were significantly more extended than on Lower force side in standing (P=0.012) and knee excursion during weight acceptance phase in gait was significantly larger in Higher side than in Lower side (P=0.006), while the other parameters were not significantly different. As to the clinical data, Higher force side had greater BMD, compared to Lower force side. In terms of Kellgren-Lawrence scale and femorotibial angle on plain radiographs, there were no significant differences between Higher and Lower force side.Conclusions: Based on loading asymmetry in the present study, lower BMD was observed on Lower force side in patients with knee OA. Therefore, it is helpful for orthopedic surgeons to examine side-to-side differences of bone mineral density or extension limitation during standing for evaluation of the loading condition in patients with bilateral knee OA.
Three-column Subdivision for Isolated Posterolateral Tibial Plateau Fractures and Perspective Surgical Approachs
Authors: Sim Jae Ang , Park Ji Hyeon , Na Young Gon , Lee Byung Hoon 
Published: January 2021

Abstract
BackgroundManagement of the tibial plateau fracture involving posterolateral compartment is technically challenging. This study aimed to introduce a computed tomography-based classification of the posterolateral compartment of tibial plateaus based on the fibula and to propose the individualized surgical approaches for each zone; and 2) to determine the surgical approach based on the classification, would achieve a safe and effective reduction and can improve postoperative clinical outcomes.MethodsEighteen cases of tibia plateau fracture involved the isolated posterolateral compartment in a single institution were retrospectively analyzed. The posterolateral compartment of tibial plateau was segmented into three zones based on the fibular position and individualized surgical approach was proposed for each zone. In anterior Zone I, surgical treatment was performed using an extended anterolateral approach and patient was placed in the supine position; In middle Zone II, using the transfibular approach in the supine position; In posterior Zone III, using the posteromedial approach in prone. Articular reduction (intra-articular step off in CT images) and mechanical medial proximal tibial angle (mMPTA) in simple radiographs taken in the immediate postoperative period and clinical outcomes of the Lysholm knee scoring scale and range of motion were evaluated at postoperative 1-year follow-up,ResultsIn all cases, anatomical articular reduction (intra-articular step off < 2 mm) was achieved, maintained for the follow-up period. The average mMPTA was increased from 87.6º before surgery to 88.2º in immediate postoperative period (p = 0.060), and maintained for the follow-up period (mean 89.9º at one-year follow-up). At the 1-year follow-up, the knee range of motion averaged 140 degrees and the Lysholm knee function scored 95.0 points.ConclusionAn individualized surgical approach and fixation according to three-zone subdivision for isolated posterolateral tibial plateau fractures provided an effective and safe method to treat posterolateral tibial plateau fractures.Level of evidence: Therapeutic study, IV
High Incidence of Postoperative Silent Venous Thromboembolism in Ulcerative Colitis
Authors: Shimada Norimitsu , Ohge Hiroki , Kitagawa Hiroki , Yoshimura Kosuke , Shigemoto Norifumi , Watadani Yusuke , Uegami Shinnosuke , Uemura Kenichiro , Takahashi Shinya 
Published: January 2021

Abstract
Purpose: The incidence of postoperative venous thromboembolism (VTE) is high in patients with inflammatory bowel diseases. We aimed to analyze the incidence and predictive factors of postoperative VTE.Methods: Patients with ulcerative colitis who underwent colon and rectum surgery during 2010–2018 were included. We retrospectively investigated the incidence of postoperative VTE.Results: A total 140 cases of colorectal surgery were included. Postoperative VTE was detected in 24 (17.1%). All patients with VTE had no specific symptoms related to thrombus, except one pulmonary embolism. Portal–mesenteric venous thrombosis was the most frequent (18, 75%); of these, 15 patients underwent total proctocolectomy (TPC) with ileal pouch–anal anastomosis (IPAA). In univariate analysis, VTE occurred more frequently in patients with neoplasia than refractory to medications (27.2% vs. 12.5%; p<0.031). TPC with IPAA was more associated with developing VTE (28%) than total colectomy (10.5%) or proctectomy (5.9%). On logistic regression analysis of predictive risk factors, TPC with IPAA, total colectomy, longer operative time (>4 hours), and high serum D-dimer levels (>5.3 μg/mL) the day following surgery were identified. Conclusion: Postoperative VTE occurred frequently and asymptomatic, especially after TPC with IPAA. D-dimer the day after surgery may be useful predictor of VTE.
Intrauterine Growth Restriction Weakens Anticontractile Influence of NO&nbsp;in Coronary Arteries of Adult Rats&nbsp;
Authors: Selivanova Ekaterina , Shvetsova Anastasia , Shilova Lyubov , Tarasova Olga , Gaynullina Dina 
Published: January 2021

Abstract
Intrauterine growth restriction (IUGR) is one of the most common pathologies of pregnancy. The cardiovascular consequences of IUGR do not disappear in adulthood and can manifest themselves in pathological alterations of vasomotor control. The hypothesis was tested that IUGR weakens anticontractile influence of NO and augments procontractile influence of Rho-kinase in arteries of adult offspring. To model IUGR in the rat, dams were 50% food restricted starting from the gestational day 11 till delivery. Mesenteric and coronary arteries of male offspring were studied at the age of 3 months using wire myography, qPCR, and Western Blotting. Contractile responses of mesenteric arteries to α1-adrenoceptor agonist methoxamine as well as influences of NO and Rho-kinase did not differ between control and IUGR rats. However, coronary arteries of IUGR rats demonstrated elevated contraction to thromboxane A2 receptor agonist U46619 due to weakened anticontractile influence of NO and enhanced role of Rho-kinase in the endothelium. This was accompanied by reduced abundance of SODI protein and elevated content of RhoA protein in coronary arteries of IUGR rats. IUGR considerably changes the regulation of coronary vascular tone in adulthood and, therefore, can serve as a risk factor for the development of cardiac disorders.