bluuebunny/crossref_metadata_2025_split huggingface dataset:
Consumers’ responses to food fraud risks: an economic experiment
Authors: McCallum Chloe S , Cerroni Simone , Derbyshire Daniel , Hutchinson W George , Nayga Jr. Rodolfo M 
Published: June 2021

Abstract
This artefactual field experiment explores consumers’ willingness-to-pay (WTP) price premiums for fish products to avoid the risk and uncertainty of purchasing inauthentic produce. The influence of subjective probabilistic beliefs, risk and ambiguity preferences is investigated. Participants’ WTP is elicited using experimental auctions, while behavioural factors are elicited using incentivised and incentive-compatible methods: the quadratic scoring rule and multiple price lists. Results show that consumers are willing to pay a premium to avoid food fraud and purchase an authentic fish product. This premium is higher under uncertainty than risk, likely driven by ambiguity preferences which affect consumers’ purchasing under uncertainty.
Racial disparity in excess mortality in Brazil during COVID-19 times
Authors: Marinho Maria Fatima , Torrens Ana , Teixeira Renato , Brant Luisa Campos Caldeira , Malta Deborah Carvalho , Nascimento Bruno Ramos , Ribeiro Antonio Luiz Pinho , Delaney Richard , de Paula Pedro do Carmo Baumgratz , Setel Philip , Sampaio Jhames Matos , Nogales-Vasconcelos Ana Maria 
Published: June 2021

Abstract
We evaluated the impact of the COVID-19 pandemic on excess mortality by race/skin colour in Brazil, between epidemiological weeks 12 and 50 of 2020. We compared the 2020 point estimate and the expected point estimate applying 2019 mortality rates to the 2020 population. There was an excess of 187 002 deaths (+20.2%) compared to the expected. Excess mortality was 26.3% (23.3–29.3%) among blacks/browns compared to 15.1% (14.1–16.1%) among whites (58.9% of excess among black/browns). Age-standardized rates increased from 377 to 419/100 000 among blacks/browns compared to 328 to 398/100 000 in whites, resulting in 9% relative risk. Excess mortality in Brazil depicts a considerable gap, with increased mortality in all age groups in the black/brown population.
Hierarchy of transcription factor network in Escherichia coli K-12: H-NS-mediated silencing and Anti-silencing by global regulators
Authors: Ishihama Akira , Shimada Tomohiro 
Published: June 2021

ABSTRACT
Transcriptional regulation for genome expression determines growth and adaptation of single-cell bacteria that are directly exposed to environment. The transcriptional apparatus in Escherichia coli K-12 is composed of RNA polymerase core enzyme and two groups of its regulatory proteins, seven species of promoter-recognition subunit sigma and about 300 species of transcription factors. The identification of regulatory targets for all these regulatory proteins is critical toward understanding the genome regulation as a whole. For this purpose, we performed a systematic search in vitro of the whole set of binding sites for each factor by gSELEX system. This review summarizes the accumulated knowledge of regulatory targets for more than 150 TFs from E. coli K-12. Overall TFs could be classified into four families: nucleoid-associated bifunctional TFs; global regulators; local regulators; and single-target regulators, in which the regulatory functions remain uncharacterized for the nucleoid-associated TFs. Here we overview the regulatory targets of two nucleoid-associated TFs, H-NS and its paralog StpA, both together playing the silencing role of a set of non-essential genes. Participation of LeuO and other global regulators have been indicated for the anti-silencing. Finally, we propose the hierarchy of TF network as a key framework of the bacterial genome regulation.
Varieties of Financial Stressors and Midlife Health Problems, 1996–2016
Authors: Wolfe Joseph D , Baker Elizabeth H , Uddin Jalal , Kirkland Stephanie 
Published: June 2021

Abstract

Objectives
Financial stressors such as wealth loss, indebtedness, and bankruptcy have gained the attention of public health scholars since the Great Recession. In this study, we extend this area of research by comparing the mental and physical impact of multiple financial stressors during midlife, a pivotal period in the life course for wealth accumulation and disease onset.

Methods
With data from the National Longitudinal Survey of Youth 1979 (www.nlsinfo.org), an ongoing survey of adult men and women in the United States, we used logistic regression to estimate the associations between financial stressors and the risk of a psychiatric disorder or high blood pressure diagnosis from ages 31–39 in 1996 to ages 50–59 in 2016 (N = 7,143). Financial stressors include multiple types of wealth loss, debt, and bankruptcy.

Results
Even after adjusting for a comprehensive set of confounders, many of the financial stressors we considered had similar positive associations with the risk of a psychiatric disorder, whereas only debt and bankruptcy were associated with the risk of high blood pressure. The best-fitting models for both health outcomes included a simple indicator of indebtedness. Stock losses were not significantly associated with either health outcome.

Discussion
Given the recent volatility in the U.S. economy, our results highlight the potential loss of health that may occur if nothing is done to prevent economically vulnerable populations from sliding into financial crisis. Our results also emphasize the need for additional research to develop individual-level interventions to improve health among those already experiencing financial difficulties.
Adult Children’s Educational Attainment and Parent Health in Mid- and Later-Life
Authors: Dennison Christopher R , Lee Kristen Schultz 
Published: June 2021

AbstractObjectivesIntergenerational models of adult health contend that children’s educational attainments influence the health and well-being of their parents. However, it is unclear how much of this association is confounded by background characteristics that predict both children’s educational attainments and parents’ subsequent health, particularly in the United States.MethodsData from the National Longitudinal Study of Adolescent to Adult Health Parent Study are used to examine how having no children who completed college influences parents’ self-rated health and depressive symptoms. We rely on propensity score methods to more squarely assess this relationship net of potential confounding bias and to test for heterogeneity in the consequences associated with having no children who completed college.ResultsHaving no children who completed college is negatively associated with parents’ self-rated health and positively associated with depressive symptoms. After statistically balancing differences in background characteristics between groups, these associations remain, though the magnitude of the coefficients is attenuated. Supplemental matching analyses suggest that while the association between children’s education and self-rated health might be spurious, the association with depressive symptoms is more robust. Additionally, among parents with the highest propensity for having no children who complete college, the consequences on depressive symptoms are greatest.DiscussionThis study pays particular attention to selection-related concerns surrounding the association between offspring educational attainment and parent well-being in the United States. These findings are important given the call for investments in children’s educational opportunities as promoting both the well-being of adult children and their parents.
Structure–function analysis of a new PL17 oligoalginate lyase from the marine bacterium Zobellia galactanivorans DsijT
Authors: Jouanneau Diane , Klau Leesa J , Larocque Robert , Jaffrennou Agathe , Duval Ghislain , Le Duff Nolwen , Roret Thomas , Jeudy Alexandra , Aachmann Finn L , Czjzek Mirjam , Thomas François 
Published: June 2021

Abstract
Alginate is a major compound of brown macroalgae and as such an important carbon and energy source for heterotrophic marine bacteria. Despite the rather simple composition of alginate only comprising mannuronate and guluronate units, these bacteria feature complex alginolytic systems that can contain up to seven alginate lyases. This reflects the necessity of large enzyme systems for the complete degradation of the abundant substrate. Numerous alginate lyases have been characterized. They belong to different polysaccharide lyase (PL) families, but only one crystal structure of a family 17 (PL17) alginate lyase has been reported to date, namely Alg17c from the gammaproteobacterium Saccharophagus degradans. Biochemical and structural characterizations are helpful to link sequence profiles to function, evolution of functions and niche-specific characteristics. Here, we combined detailed biochemical and crystallographic analysis of AlyA3, a PL17 alginate lyase from the marine flavobacteria Zobellia galactanivorans DsijT, providing the first structure of a PL17 in the Bacteroidetes phylum. AlyA3 is exo-lytic and highly specific of mannuronate stretches. As part of an “alginate utilizing locus”, its activity is complementary to that of other characterized alginate lyases from the same bacterium. Structural comparison with Alg17c highlights a common mode of action for exo-lytic cleavage of the substrate, strengthening our understanding of the PL17 catalytic mechanism. We show that unlike Alg17c, AlyA3 contains an inserted flexible loop at the entrance to the catalytic groove, likely involved in substrate recognition, processivity and turn over.
High-Quality Listening Supports Speakers’ Autonomy and Self-Esteem when Discussing Prejudice
Authors: Itzchakov Guy , Weinstein Netta 
Published: June 2021

Abstract
We examined how the experience of high-quality listening (attentive, empathic, and nonjudgmental) impacts speakers’ basic psychological needs and state self-esteem when discussing the difficult topic of a prejudiced attitude. Specifically, we hypothesized that when speakers discuss a prejudiced attitude with high-quality listeners, they experience higher autonomy, relatedness, and self-esteem than speakers who share their prejudiced attitude while experiencing moderate listening. We predicted that autonomy need satisfaction would mediate the effect of listening on speakers’ self-esteem even when relatedness, a well-documented predictor of self-esteem, is controlled for in mediation models. Two experiments that manipulated listening through in-person interactions with high-quality or moderate listeners supported these hypotheses. Theoretical and practical implications are discussed, with a focus on the role of experiencing high-quality listening for speakers’ state self-esteem during difficult conversations.
Peer mentors’ role in school-based health promotion: qualitative findings from the Young & Active study
Authors: Wehner Stine Kjær , Tjørnhøj-Thomsen Tine , Bonnesen Camilla Thørring , Madsen Katrine Rich , Jensen Marie Pil , Krølner Rikke Fredenslund 
Published: June 2021

SummaryPeer-led interventions are highlighted as promising strategies to promote health among adolescents, but little is known about the mechanisms underlying this approach. To better understand the role of peer mentors (PMs) as implementers in school-based health promotion, we combined participant observations, focus group interviews and video recordings to explore high school students’ reception of a peer-led intervention component (Young & Active). Young & Active aimed to increase well-being among first-year high school students (∼16 years of age) through the promotion of movement and sense of community and was implemented during the school year 2016–2017 in a larger school-based intervention study, the Healthy High School study in Denmark. The Healthy High School study was designed as a cluster-randomized controlled trial with 15 intervention schools and 15 control schools. At each intervention school, university students in Sports Science and Health (members of the research group) facilitated an innovation workshop aiming at inspiring all first-year students to initiate movement activities at schools. The findings illustrate potentials and challenges implied in the PM role. The peer mentors’ profound commitment, as well as their response and sensibility to situational contingencies, were found to be significant for the students’ reception and experience of the intervention. In conclusion, the specific job of PMs as implementers seems to consist of simultaneously following a manual and situationally adjusting in an emerging context balancing commitment and identification to the target group and the intervention project.
The role of sport in coping and resilience amongst resettled South Sudanese youth in Australia
Authors: Pittaway Troy , Dantas Jaya A R 
Published: June 2021

Summary
In this article, the use of sport as a coping strategy by South Sudanese youth who have suffered the trauma of forced migration is examined. This article explores the relationship that has emerged between the young people and sport, in particular basketball, and how they use their participation in basketball and sports to cope with the stressors of their lives. The research intended to explore to what degree sport can play in improving mental health and what mental health interventions, in general, were being sought by this marginalized demographic. This qualitative study was underpinned by the psychosocial conceptual framework. We undertook semi-structured interviews with 23 South Sudanese youth aged 14–21 years, we also conducted focus groups of 11 South Sudanese elders and parents. The results of this research were feed back to the wider South Sudanese community through two forums. The data collected were analyzed using thematic analysis. The results of the study identified sport as an important coping strategy for the participants, both as a diversion from drug and alcohol misuse, potential criminal activity and as a way to self-manage the symptoms of anxiety and depression they were experiencing, and a mechanism to enhance self-worth. The study also indicated there was a lack of mental health interventions for these young people and that they had shown a great deal of resilience to develop their own ways to deal with the trauma they had experienced. The research reported positive associations of wellbeing and participation in sport, however more research needs to be conducted to ascertain the extent to which sport impacts mental health and how this can be incorporated into interventions for Sudanese youth and young people from similar forced migration and resettlement backgrounds. This study suggested that sport can be a driving force of good for many of the young people’s lives, worthy of further research.
Burden-sharing: the US, Australia and New Zealand alliances in the Pacific islands
Authors: Wallis Joanne , Powles Anna 
Published: June 2021

Abstract
One of President Joseph Biden's foreign policy priorities is to ‘renew’ and ‘strengthen’ the United States' alliances, as they were perceived to have been ‘undermined’ during the Trump administration, which regularly expressed concern that allies were free-riding on the United States' military capability. Yet the broad range of threats states face in the contemporary context suggests that security assistance from allies no longer only—or even primarily—comes in the form of military capability. We consider whether there is a need to rethink understandings of how alliance relationships are managed, particularly how the goals—or strategic burdens—of alliances are understood, how allies contribute to those burdens, and how influence is exercised within alliances. We do this by analysing how the United States–Australia and Australia–New Zealand alliances operate in the Pacific islands. Our focus on the Pacific islands reflects the United States' perception that the region plays a ‘critical’ role in helping to ‘preserve a free and open Indo-Pacific region’. We conclude that these understandings need to be rethought, particularly in the Pacific islands, where meeting non-traditional security challenges such as economic, social and environmental issues, is important to advancing the United States, Australia and New Zealand's shared strategic goal of remaining the region's primary security partners and ensuring that no power hostile to their interests establishes a strategic foothold.
Laser texturing of a St. Jude Medical RegentTM mechanical heart valve prosthesis: the proof of concept
Authors: Vigano Giorgio , ten Brink Gert H , Groenendijk Max , Sipkema Ronald , Pollack Daniël K M , Mariani Massimo A , Kooi Bart J 
Published: June 2021

Abstract

OBJECTIVES
The liquid–solid interactions have attracted broad interest since solid surfaces can either repel or attract fluids, configuring a wide spectrum of wetting states (from superhydrophilicity to superhydrophobicity). Since the blood–artificial surface interaction of bileaflet mechanical heart valves essentially represents a liquid–solid interaction, we analysed the thrombogenicity of mechanical heart valve prostheses from innovative perspectives. The aim of the present study was to modify the surface wettability of standard St. Jude Medical Regent™ occluders.

METHODS
Four pyrolytic carbon occluders were irradiated by means of ultra-short pulse laser, to create 4 different nanotextures (A–D), the essential prerequisite to achieve superhydrophobicity. The static surface wettability of the occluders was qualified by the contact angle (θ) of 2 µl of purified water, using the sessile drop technique. The angle formed between the liquid–solid and the liquid–vapour interface was the contact angle and was obtained by analysing the droplet images captured by a camera. The morphology of the occluders was characterized and analysed by a scanning electron microscope at different magnifications.

RESULTS
The scanning electron microscope analysis of the textures revealed 2 different configurations of the pillars since A and B showed well-rounded shaped tops and C and D flat tops. The measured highest contact angles were comprised between 108.1° and 112.7°, reflecting an improved hydrophobicity of the occluders. All the textures exhibited, to different extents, an orientation (horizontal or vertical), which was strictly related to the observed anisotropy.

CONCLUSIONS
In this very early phase of our research, we were able to demonstrate that the intrinsic wettability of pyrolytic carbon occluders can be permanently modified, increasing the water repellency.
Topological Structure of the Solution Sets for a Nonlinear Delay Evolution
Authors: Wang Rong-Nian , Ma Zhong-Xin , Miranville Alain 
Published: June 2021

AbstractWe consider a nonlinear delay evolution equation with multivalued perturbation on a noncompact interval. The nonlinearity, having convex and closed values, is upper hemicontinuous with respect to the solution variable. A basic question on whether there exists a solution set carrying $R_{\delta }$-structure remains unsolved when the operator families generated by the principal part lack compactness. One of our main goals is to settle this question in the affirmative. Moreover, we prove that the solution map, having compact values, is an $R_{\delta }$-map, which maps any connected set into a connected set. It is then exploited to deal with the existence in the large for a nonlocal problem. Finally, several examples are worked out in detail, illustrating the applicability of our general results.
Alliance Dynamics in the Shadow of Shifting Power
Authors: Krainin Colin , Schub Robert 
Published: June 2021

Abstract
Alliances are costly to form and to terminate, and yet alliances change frequently. Scholars typically attribute these decisions to static factors, such as the power balance, and retrospective ones, such as past power shifts. We highlight another factor: prospective changes, particularly anticipated military strength shifts. We analyze a three-country bargaining model of alliances and war that incorporates forward-looking power dynamics. The model, unlike those restricting players to set roles, flexibly allows players to ally in any arrangement. We find that alliance arrangements that are optimal when power is static are often suboptimal when power fluctuates. Maintaining prior alliances despite expected power shifts may even lead to preventive war. States thus strategically look to the future to identify optimal alliances in the present. Quantitative analyses corroborate the expectation. As the anticipated size of power shifts increases, alliance changes become more common. Accordingly, states navigate expected changes in the international landscape by rearranging current alliance commitments that can help minimize the risk of conflict. When power balances are in flux, malleable institutional arrangements may prove preferable to rigid ones.
Bactericidal activities and post-antibiotic effects of ofloxacin and ceftriaxone against drug-resistant Salmonella enterica serovar Typhi
Authors: Wain John , Simpson Julie A , Thi Diem Nga Luong , Song Diep To , Thanh Duy Pham , Baker Stephen , Day Nicholas P J , White Nicholas J , Parry Christopher M 
Published: June 2021

Abstract

Background
The clinical response to ceftriaxone in patients with typhoid fever is significantly slower than with ofloxacin, despite infection with Salmonella enterica serovar Typhi (S. Typhi) isolates with similar susceptibilities (MIC 0.03–0.12 mg/L). The response to ofloxacin is slower if the isolate has intermediate susceptibility (MIC 0.25–1.0 mg/L).

Objectives
To determine the bactericidal activity and post-antibiotic effect (PAE) of ceftriaxone and ofloxacin against S. Typhi.

Methods
The mean time to reach a 99.9% reduction in log10 count (bactericidal activity) and PAE of ceftriaxone and ofloxacin were determined for 18 clinical isolates of S. Typhi in time–kill experiments (MIC range for ofloxacin 0.06–1.0 mg/L and for ceftriaxone 0.03–0.12 mg/L).

Results
The mean (SD) bactericidal activity of ofloxacin was 33.1 (15.2) min and 384.4 (60) min for ceftriaxone. After a 30 min exposure to ofloxacin, the mean (SD) duration of PAE was 154.7 (52.6) min. There was no detectable PAE after 1 h of exposure to ceftriaxone. For ofloxacin, bactericidal activity and PAE did not significantly differ between isolates with full or intermediate susceptibility provided ofloxacin concentrations were maintained at 4×MIC.

Conclusions
Infections with S. Typhi with intermediate ofloxacin susceptibility may respond to doses that maintain ofloxacin concentrations at 4×MIC at the site of infection. The slow bactericidal activity of ceftriaxone and absent PAE may explain the slow clinical response in typhoid.
Building Brands for the Emerging Bicultural Market: The Appeal of Paradox Brands
Authors: Rodas Maria A , John Deborah Roedder , Torelli Carlos J 
Published: June 2021

Abstract
Bicultural consumers now represent a third of the US population and are the fastest growing demographic group in the United States. This shift in consumer markets presents a challenge for marketers as they try to design brand strategies to serve this important group. In this article, the authors show that certain types of brands, specifically paradox brands that incorporate contradictory brand meanings, are particularly appealing to bicultural consumers. Results from seven studies reveal that bicultural consumers evaluate paradox brands more favorably and choose paradox brands more than traditional brands without contradictions. Furthermore, bicultural consumers exhibit more favorable evaluations and greater choice of paradox brands than do monocultural consumers. These cultural differences are attributable to greater cognitive flexibility found among biculturals, particularly those who adopt an acculturation strategy of integrating their different cultural identities. Greater cognitive flexibility, in turn, prompts stronger engagement with a paradox brand, which contributes to more favorable brand evaluations and choice. Contributions of this research for understanding bicultural consumers, marketing to bicultural consumers, and directions for future research are discussed.