bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical profile of hemodialysis patients attending a tertiary care hospital in Delhi, India
Authors: Kumar Mithilesh , Saini Shipra , Parashar Lokesh , Chetiwal Rajesh , Kalra Tanisha , Kalra Nikhita 
Published: November 2021

Background: CKD (chronic kidney disease) is one of the major complications of diabetes and hypertension. With increase in prevalence of non-communicable diseases, the patients presenting with the symptoms of CKD are also rising. Most of the patients suffering from CKD eventually land up on renal replacement therapy, putting extra burden economically as well as psychologically to the self and their family. The aim of the study is to find out the socio demographic and clinical profile of the patients suffering from CKD attending a tertiary care hospital in Delhi.Methods: It was a record based descriptive analysis, conducted between January 2019 and June 2019 in one of the ESIC (Employee State Insurance Corporation) hospital of Delhi. Medical Records of the only those patients were considered whose complete data were present in the record file. Data about Socio demographic profiles , clinical data, duration of CKD, duration of haemodialysis, viral markers, number of blood transfusions, vascular access, number of failed AV fistula etc. were entered in MS Excel and analysed through SPSS 11.Results: Hospital records of 473 CKD patients undergoing hemodialysis were analyzed. It was found that 315 (67%) were males and 158 (33%) were females. Majority of the patients i.e. 245 were in the age group of 41-60 years followed by 166 who were in the age group of 21 to 40. Out of total patients, 195 (41.2%) participants were undergoing hemodialysis twice a week, 276 (58.4%) thrice a week, 2 (0.4) patients were undergoing hemodialysis session four times a week. Majority of the participants i.e. 414 (88%) were Hindu. Out of total 473 participants, 439 (93%) participants had sero negative for viral marker (i.e. HbsAg, HCV, HIV I and II) and 33 (7%) participants were sero positive for viral marker. Most common etiology of CKD was found to be hypertension in our study followed by diabetes.Conclusions: Patients suffering from chronic kidney diseases are increasing day by day with increasing prevalence of hypertension. Most of the patients of CKD patients were middle aged males. Most of the patients have to visit 3 times a week to any health care institution for hemodialysis. Many of the patients are getting infected with viral hepatitis during course of the illness.
Vinculación del deudor solidario en el procedimiento de fiscalización, determinación, discusión y cobro de obligaciones tributarias. Línea jurisprudencial
Authors: García Pinzón Paula Andrea 
Published: November 2021

En este artículo se hace un análisis de la jurisprudencia proferida por el Consejo de Estado, Sección Cuarta, entre los años 2003 a 2019, relacionada con la vinculación del
The work analyzes the jurisprudence issued by the Council of State, Section Four, between the years 2003 to 2019 related to the connection of the joint debtor in the procedure of inspection, determination, discussion and collection of the tax obligation in charge of the direct taxable person, materialized in a jurisprudential line, in order to determine its historical position, as well as to recognize the line that is currently being applied, in order to conclude publicize the possible consequences and solutions to the problem regarding the procedural link of this subject.
deudor solidario en el procedimiento de fiscalización, determinación, discusión y cobro de la obligación tributaria a cargo del sujeto pasivo directo, materializado en una línea jurisprudencial, con el fin de determinar la evolución de este tema en relación con la jurisprudencia como fuente del derecho, así como también reconocer la línea que actualmente se está aplicando, para así, a modo de conclusión, dar a conocer las posibles consecuencias y soluciones a la problemática respecto a la vinculación procesal de este sujeto.
Comparison of pain intensity, smooth muscle cells density, and alpha-smooth muscle actin expression in ovarial and peritoneal endometriosis
Authors: Sutrisno Sutrisno , Nooryanto Muhammad , Gani Shella Widya 
Published: November 2021

HIGHLIGHT1. Pain intensity, smooth muscle cells density, and alpha-SMA expression can be used to analyze the role of smooth muscle in endometriosis.2. Compared to healthy individuals, those with endometriosis have higher pain intensity, smooth muscle cells density, and alpha-SMA expression. 3. Among endometriotic patients, those with peritoneal endometriosis have higher pain intensity, smooth muscle cells density, and alpha-SMA expression than those with ovarial endometriosis.3. The expression of alpha-SMA, smooth muscle density, and pain intensity were found to correlate significantly in endometriosis. ABSTRACTObjectives: to identify the role of smooth muscle through the analysis of smooth muscle cells density, expression of a-SMA, and the pain intensity.Materials and Methods: Study design is a cross sectional analytic observational. Study sample consists of women with ovarial endometrios and women with peritoneal endometriosis that undergo laparoscopy and laparotomy in RSUD Saiful Anwar Malang and RSIA Melati Malang from January until December 2019. There are 16 samples: 8 samples of ovarial endometriosis and 8 samples of peritoneal endometriosis. Smooth muscle cell density was analyzed by comparing the number of smooth muscle cells with the total area of endometriosis tissue in one microscopical field. a-SMA expression obtained by immunohistochemistry. Degree of pain obatined by filling the part 1 point 1-11 of EHP-30 queistionnaire the day after the procedure. Data was analyzed by Independent T-test and Pearson correlation.Results: Pain intensity, smooth muscle cells density, and a-SMA expression is higher in the endometriosis patient compared to healthy individual. Pain intensity, smooth muscle cells density, and a-SMA expression is lower in the ovarial endometriosis compared to peritoneal endometriosis.Conclusion: There are a significant correlation between the expression of a-SMA, smooth muscle density, and pain intensity in endometriosis.
Hesperidin Interaction with HMG-CoA-Reductase Enzyme in Hypercholesterolemia: A Study in Silico
Authors: Oktaviani Annisa Rizqi Dwi , Aprillia Veronica Shania , Suhartono Eko , Komari Noer 
Published: November 2021

Abstract: Dyslipidemia is a degenerative disease occurred with increased levels of fat and cholesterol levels in blood. One of the proteins used as anti-cholesterol is an HMG-CoA-Reductase. Hesperidin in orange peel can reduce cholesterol levels by interacting with HMG-CoA-Reductase. To prove this, an in silico method was used by using swissdock.ch (http://swissdock.ch/docking#). The receptor protein in dyslipidemia was obtained from the RCSB Protein Data Bank (https://www.rcsb.org) namely HMG-CoA-reductase receptor with code PDB: 1HW9. The natural ligand, hesperidin, was obtained from PubChem with code: 10621 (https://pubchem.ncbi.nlm.nih.gov/). Protein was prepared by omitting the natural ligand residues present in the protein. Ligand and protein preparations were used by the chimera 1.15. The result of this study indicated that the interaction of hesperidin with several amino acid recidues was predicted to provide inhibitory activity on HMG-CoA reductase as the protein target. Inhibition of HMG-CoA reductase will reduce mevalonate synthesis so that cholesterol levels will decrease. Keywords: hesperidin, HMG-CoA-Reductase, cholesterol, dyslhahipidemia
Pengembangan Modul Sistem Peredaran Darah Berbasis Literasi Sains dan Bermuatan Karakter Kreatif
Authors: Amalia Rizky Nyna , Pasani Chairil Faif , Yulinda Ratna 
Published: November 2021

AbstrakPenelitian ini merupakan penelitian pengembangan modul sistem peredaran darah manusia berbasis literasi sains dan bermuatan karakter kreatif untuk peserta didik SMP. Bahan ajar yang dipilih untuk penelitian ini berupa modul. Penelitian ini bertujuan untuk mendeskripsikan validitas modul pembelajaran IPA SMP berbasis literasi sains dan bermuatan karakter kreatif pada materi sistem peredaran darah manusia berdasarkan penilaian para ahli. Modul dikembangkan dengan model pengembangan 4D, akan tetapi pada penelitian ini hanya sampai pada tahap develop yaitu validasi pakar. Instrumen yang digunakan pada penelitian ini adalah lembar validasi. Rata-rata skor keseluruhan validitas adalah 92,68% menunjukkan bahwa modul memiliki tingkat validitas yang sangat baik. Hal ini ditinjau dari lima aspek: (1) aspek format modul memperoleh skor 93,33 kriteria sangat valid, (2) aspek bahasa memperoleh skor 94,17 kriteria sangat valid, (3) aspek isi modul peserta didik memperoleh skor 91,67 kriteria sangat valid, (4) aspek penyajian memperoleh skor 92,59 kriteria sangat valid, dan (5) aspek manfaat media ajar memperoleh skor 91,67 juga dengan kriteria sangat valid. Berdasarkan hasil penelitian yang diperoleh, dapat disimpulkan modul pembelajaran IPA SMP berbasis literasi sains dan bermuatan karakter kreatif pada materi sistem peredaran darah manusia layak untuk digunakan. This research was about developing the module of human circulatory system science literacy-based and containing creative character for Junior High School students. PISA result 2018 showed science literacy skill in Indonesia was still low. The learning material spread nowadays contains few creative character content. This research aimed to describe the validity of the Science Learning Module of Junior High School Science Literacy-Based and contain creative character in a human circulatory system based on the experts’ assessment. The module was developed using the 4 D development model (Define, Design, Develop, Disseminate); however, this research only until the development stage, namely the experts’ validation. The instrument used in this research was a validation sheet. The research results show that the module has an excellent validity level reviewed from five aspects: (1) the aspect of module format obtains score 93.33 in highly valid criteria, (2) the language aspect obtains score 94.17 in highly valid criteria, (3) the aspect of students’ module content obtains score 91.67 in highly valid criteria, (4) presentation aspect obtains score 92.59 with highly valid criteria, (5) the aspect of teaching material benefit obtains score 91.67 also with highly valid criteria. Based on the research results obtained, it can be concluded that the Science learning module of Junior High School Science literacy based on a creative character in human circulatory system material is feasible to use.
Pengembangan Modul IPA Pada Materi Sistem Organ Dan Organisme Berbasis STEM-Inkuiri untuk Meningkatkan Literasi Sains
Authors: Irmawati Ida , Syahmani Syahmani , Yulinda Ratna 
Published: November 2021

Penelitian ini merupakan penelitian pengembangan modul pembelajaran IPA berbasis STEM-Inkuiri pada materi sistem organ dan organisme. Penelitian ini bertujuan untuk mengetahui validitas dan reliabilitas modul berbasis STEM-Inkuiri untuk meningkatkan literasi sains. Model pengembangan yang digunakan merupakan model pengembangan 4D oleh Thiagarajan hanya sampai pada tahap validasi para ahli (develop). Hasil penelitian yang diperoleh berdasarkan data angket validasi yang dilakukan oleh enam orang ahli yang dianalisis menggunakan formula Aiken’s V serta analisis reliabilitas Alpha Cronbach dengan bantuan SPSS 24. Validitas modul, rencana pelaksanaan pembelajaran dan tes literasi secara berturut-turut sebesar 0,87, 0,88 dan 0,90 dinyatakan valid dengan kriteria “sangat tinggi”. Nilai reliabilitas modul, rencana pelaksanaan pembelajaran dan tes literasi secara berturut-turut berdasarkan Cronbach Alpha sebesar 0,81, 0,88 dan 0,91 yang artinya memiliki reliabilitas “sangat tinggi”. Hal ini menunjukkan bahwa pengembangan modul sistem organ dan organisme berbasis STEM-inquiry telah memenuhi kriteria valid dan reliabel sehingga layak untuk digunakan. This research is research on the development of a STEM-Inquiry-based science module on organ systems and organisms. The purpose of this study was to know the validity and reliability of the STEM-Inquiry based module to improve scientific literacy. This research used the 4D development models by Thiagarajan, only reached the developer's validation stage. The subjects in this study were experts consisting of academics and practitioners. The data was collected through a validation questionnaire by six experts and analyzed using the Aiken's V formula and the reliability analysis of the Alpha Cronbach formulas with the help of SPSS 24. Module validity, lesson plan and literacy test results were 0.87, 0.88 and 0.90 respectively were declared valid with "very high" criteria. Reliability module, lesson plan and literacy test results based on Cronbach Alpha are 0.81, 0.88 and 0.91, respectively, which meant they had "very high" reliability. This shows that the development of the organ system and organism module on STEM-inquiry-based has met the valid and reliable criteria so that it is feasible to use.
Pengembangan Lembar Kerja Peserta Didik Berbasis Kearifan Lokal untuk Pembelajaran Matematika SMP
Authors: Sa'diah Halimatus , Karim Karim , Suryaningsih Yuni 
Published: November 2021

Matematika masih menjadi momok yang ditakuti siswa karena dirasa sulit. Siswa membuat kesalahan dalam menyelesaikan masalah karena tidak dapat mengubah soal cerita ke bentuk model matematika khususnya pada materi Sistem Persamaan Linear Dua Variabel (SPLDV). Berdasarkan hal tersebut diperlukan perangkat pembelajaran yang menarik dan kontekstual salah satunya yaitu dengan mengembangkan Lembar Kerja Peserta Didik (LKPD) berbasis kearifan lokal Kalimantan Selatan. Tujuan dari penelitian ini yaitu untuk menghasilkan LKPD materi sistem persamaan linear dua variabel berbasis kearifan lokal yang valid dalam pembelajaran matematika siswa kelas VIII SMP/MTs. Penelitian ini dilakukan dengan metode Research and Development menggunakan model yang dikemukakan oleh Thigarajan, Semmel & Semmel yaitu 4-D. Beberapa tahapan yang dilakukan pada penelitian ini yaitu Define, Design, dan Develop. Teknik analisis data yang digunakan dalam penelitian ini didasarkan pada uji validitas yang diperoleh melalui analisis secara kuantitatif dan kualitatif dari lembar validasi pada tahap develop yang dilakukan oleh tiga ahli. Menurut skor yang diberikan oleh ketiga ahli, didapatkan skor rata-rata 84,06%, artinya LKPD termasuk kategori cukup valid dan dapat dipergunakan dalam pembelajaran matematika. Mathematics is still a scourge that students fear because it is difficult. Students solve problems because they cannot convert storey problems into mathematical models, especially in the Two-Variable Linear Equation System materials. Based on this, interesting and contextual learning tools are needed, one of which is developing Student Worksheets (LKPD) based on South Kalimantan local wisdom. The purpose of this research is to produce LKPD material on a two-variable linear equation system based on local wisdom that is valid in learning mathematics for class VIII SMP/MTs students. This research was conducted using the Research and Development method using the 4-D model proposed by Thiagarajan, Semmel & Semmel. Several stages were carried out in this research, namely Define, Design, and Develop. The data analysis technique used in this study is based on the validity test obtained through quantitative and qualitative analysis of the validation sheet at the development stage conducted by three experts. According to the scores given by the three experts, an average score of 84.06% was obtained, meaning that the LKPD was categorized as valid and could be used in learning mathematics.
Pengembangan Media Pembelajaran Interaktif Perakitan Komputer Kelas X SMK Berbasis Web Dengan Metode Demonstrasi
Authors: Purba Harja Santana , Adini Muhammad Hifdzi , Mahfuz Muhammad Febry 
Published: November 2021

PeneIitian ini bertujuan untuk: 1) mengembangkan media pembeIajaran perakitan komputer, dan 2) menganaIisis keIayakan media pembeIajaran perakitan komputer tersebut. Adapun metode peneIitian yang digunakan adaIah Research and DeveIopment. Uji coba peneIitian bertempat di SMK Negeri 3 Banjarmasin dengan teknik pengumpuIan data berupa wawancara, angket, dan tes hasiI beIajar. Subjek peneIitian terdiri dari 30 orang siswa dan 1 orang guru mata peIajaran bersangkutan. Teknik anaIisis data yang digunakan adaIah anaIisis deskriptif kuaIitatif. Berdasarkan hasiI dari peneIitian, diketahui bahwa: 1) pengembangan media pembelajaran perakitan komputer tersebut menggunakan modeI pengembangan ADDlE, teknoIogi yang digunakan antara Iain HTML, CSS, Javascript, JQuery, Firebase, JSON, Construct2, X3DOM, dan BIend4web, 2) hasiI uji keIayakan media pembeIajaran menunjukkan bahwa media pembeIajaran Iayak dengan memenuhi tiga kriteria yakni kevaIidan, keefektivan, dan kepraktisan. HasiI uji kevaIidan yang diIakukan oleh 2 orang ahIi materi dan 2 orang ahIi media menunjukkan kriteria vaIiditas sangat tinggi. HasiI uji keefektivan yang diukur berdasarkan hasiI beIajar peserta didik memperoIeh persentase ketuntasan sebesar 80%. Sedangkan hasiI tanggapan pengguna menunjukkan respon positif dari guru dan siswa. Sehingga media pembeIajaran yang dikembangkan dapat dikatakan Iayak.
MENINGKATKAN KEMAMPUAN MENULIS TEKS INTERAKSI TRANSAKSIONAL MELALUI TEKNIK “MAGEVPRO”
Authors: Hamid Abdul 
Published: November 2021

Abstract. This classroom action research was intended to describe the implementation of the “MAGEVPRO” technique to increase the students’ability of grade VIII in writing the transactional interaction text. This research was conducted in grade VIII A at SMP Negeri 1 Banjarmasin with 33 students. This research was conducted in two cycles with the four steps: planning, acting, observing and reflecting. The quantitative data of the students’learning achievement was obtained by test (daily assessment) and the number of errors made by students was collected by error analysis. The qualitative data of the students’activities were collected through observation sheet. The result of this study showed that the implementation of the “MAGEVPRO” technique was able to increase the the students’ability of the grade VIII in writing the transactional interaction text at SMP Negeri 1 Banjarmasin. Keywords: Students’ability, transactional interaction text, “MAGEVPRO” technique Abstrak. Penelitian tindakan kelas ini bertujuan untuk mendeskripsikan penerapan teknik “MAGEVPRO” untuk meningkatkan kemampuan siswa kelas VIII dalam menulis teks interaksi transaksional. Penelitian ini dilaksanakan di kelas VIII A SMP Negeri 1 Banjarmasin dengan jumlah siswa 33 orang. Penelitian ini dilaksanakan dengan 2 siklus dengan tahapan kegiatan mulai perencanaan, pelaksanaan, pengamatan/observasi dan refleksi. Data kuantitatif berupa prestasi belajar diperoleh melalui tes (Penilaian Harian) dan banyaknya kesalahan yang dilakukan siswa diperoleh melalui kegiatan analisis kesalahan. Data kualitatif berupa aktivitas siswa diperoleh melalui lembar observasi. Hasil penelitian menunjukkan bahwa penerapan teknik “MAGEVPRO” dapat meningkatkan kemampuan siswa kelas VIII dalam menulis teks interaksi transaksional di SMP Negeri 1 Banjarmasin Kata kunci:Kemampuan siswa, teks interaksi transaksional, teknik “MAGEVPRO”.
MODEL PROJECT BASED LEARNING BERBANTUAN MEDIA “CHEMONDRO”, MOTIVASI, DAN HASIL BELAJAR
Authors: Santi Santi , Leny Leny , Suharto Bambang 
Published: November 2021

Abstract. This study aims to determine whether there are significant differences in learning motivation and learning outcomes in students between the use of PjBL learning models assisted by Chemondro android-based chemistry learning media with expository learning models. In addition, it is aimed to determine students' responses to Chemondro media on colloidal material. Classes becaming the sample were class X-TKJ A and X-TKJ B at SMK Negeri 2 Banjarmasin. The method used is a quasi-experimental with descriptive and inferential analysis techniques. This research shows that there are significant differences in motivation and student learning outcomes in classes using the PjBL model compared to the expository model. The use of Chemondro media for colloidal material perceived positive responses from students. Keywords: Project Based Learning (PjBL), Chemondro, motivation to learn, learning outcomes, Colloid Abstrak. Penelitian ini bertujuan untuk mengetahui apakah terdapat perbedaan motivasi belajar dan hasil belajar yang signifikan pada peserta didik antara penggunaan model pembelajaraan PjBL berbantuan media pembelajaran kimia berbasis android Chemondro dengan model pembelajaran ekspositori. Selain itu, untuk mengetahui respon peserta didik terhadap media Chemondro pada materi koloid. Kelas yang menjadi sampel penelitian adalah kelas X-TKJ A dan X-TKJ B di SMK Negeri 2 Banjarmasin. Metode yang digunakan adalah quasi-experiment dengan teknik analisis deskriptif dan inferensial. Penelitiian ini menunujukkan adanya perbedaan motivasi dan hasil belajar peserta didik yang signifikan pada kelas yang menggunakan model PjBL dibandingkan dengan model ekspositori. Penggunaan media Chemondro materi koloid mendapat respon positif dari peserta didik. Kata kunci: Project Based Learning (PjBL), Chemondro, motivasi belajar, hasil belajar, Koloid
STUDENTS’ VOCABULARY MASTERY TAUGHT USING HANGAROO GAME AND WORD JUMBLE
Authors: Sabila Meidiana 
Published: November 2021

Abstract. This research is to see the implementation of Hangaroo Game and Word Jumble to build the students’ vocabulary mastery. The method used is quasi-experimental research. There were students of SMP Negeri 9 Banjarmasin as the sample. As the result, the students from both classes had limited comprehension on vocabulary proven by the students’ score of pre-test. The class of experimental yielded the mean score of 20,19. The mean score was 17,29. The final result of the research was determined after the researcher had acquired the t-test result. It is found that there was no difference of students’ vocabulary mastery taught using Hangaroo Game and students taught using Word Jumble. For further research, it is hoped to be more curious and innovative to choose other media that can be used to aid the students’ vocabulary mastery. Keywords: score, Hangaroo Game, Word Jumble, vocabulary, vocabulary mastery, Lexicogrammatical