bluuebunny/crossref_metadata_2025_split huggingface dataset:
Extracting and analyzing inorganic material synthesis procedures in the literature
Authors: Makino Kohei , Kuniyoshi Fusataka , Ozawa Jun , Miwa Makoto 
Published: June 2021

Abstract
Analyzing synthesis procedures from a considerable amount of literature is required to collect structural information of material names and synthesis procedures for designing materials computationally. There are databases comprising structural data of material names and material synthesis procedures. However, the types of material in these databases and the material property values included are limited and insufficient. Moreover, they are primarily described in the literature in the natural language of the researcher who proposed the procedure, and thus they cannot be understood universally. It is, therefore, necessary to create a framework that represents textual synthesis procedures in a flow graph that contains crucial information for material development such as the order of operations and the linkage between operations and conditions. This will facilitate obtaining material insights from the literature. However, there are no large-scale studies on the extraction of synthesis procedures in the form of a graph and analysis thereof. In this study, we propose a pipeline system that extracts synthesis procedures from a text in the form of a graph with a clear order of operations and objects of conditioning from the literature. The system consists of preprocessing, entity extraction, which is based on Mat-ELMo and Bi-LSTM-CRF models, rule-based relation extraction, and selection for paragraph-containing procedures. We applied the system to a large body of literature and extracted various synthesis procedures. We performed basic analyses of the extracted procedures to examine their usability. We experimentally confirmed that some extracted procedures were specific to the target material, and some of the obvious procedures were correctly extracted.
A Moving Liver Phantom in An Anthropomorphic Thorax for SPECT MP Imaging
Authors: Panagi Sotiris , Hadjiconstanti Anastasia , Charitou George , Kaolis Demetris , Petrou Ioannis , Kyriacou Costas , Parpottas Yiannis 
Published: June 2021

Abstract
Cranio-caudal respiratory motion and liver activity cause a variety of complex myocardial perfusion (MP) artifacts, especially in the inferior myocardial wall, that may also mask cardiac defects. To assess and characterize such artifacts, an anthropomorphic thorax with moving thoracic phantoms can be utilized in SPECT MP imaging. In this study, a liver phantom was developed, and anatomically added into an anthropomorphic phantom, that encloses an ECG beating cardiac phantom and breathing lungs phantom. A cranio-caudal respiratory motion was also developed for the liver phantom and it was synchronized with the corresponding ones of the cardiac and lungs phantoms. This continuous motion could also be further divided into dynamic respiratory phases, from end-exhalation to end-inspiration, to perform SPECT acquisitions in different respiratory phases. The motion parameters, displacements and volumes, were validated by the acquired CT slices, the OsiriX and Vitrea software. Sample SPECT/16-slice-CT myocardial MP acquisitions were also performed and compared to the literature. The cardiac, lungs and liver phantoms can precisely perform, in time interval of 0.1 sec, physiological thoracic motions within an anthropomorphic thorax. This dynamic phantom assembly can be utilized for SPECT MP supine and, for first time, prone imaging to access and characterize artifacts due to different cranio-caudal respiratory amplitudes and cardiac-liver activity ratios.
Pan-Cancer Analysis of VIM Expression in Human Cancer Tissues
Authors: Blatkiewicz Małgorzata , Białas Piotr , Taryma-Leśniak Olga , Hukowska-Szematowicz Beata 
Published: June 2021

Abstract
In 2020, more than 19 million cancer cases were diagnosed. One of the best paths to more effective treatment with a chance of being cured for patients is early detection. Vimentin (VIM), as an intermediate filament protein, is broadly expressed in mesenchymal cells. VIM is responsible for several biological processes such as cellular component organization and biogenesis, metabolic processes, and biological regulation. A growing body of literature indicates that expression of the VIM gene (VIM) is disrupted in carcinomas during epithelial–mesenchymal transition. Herein, we broadly analyzed the gene expression and promoter methylation profile of VIM in 19 cancer types across The Cancer Genome Atlas (TCGA). Furthermore, the protein–protein interactions (GeneMANIA and Search Tool for the Retrieval of Interacting Genes (STRING) database) and the alteration frequency of mutations (cBioPortal database) in VIM were analyzed. We proved that VIM is overexpressed in seven of the 19 studied cancer types. For two of them, we observed an association of VIM expression with gene promoter methylation. It must be emphasized that VIM overexpression can be a potential diagnostic biomarker in selected types of cancers.
Construction of Complete Diallel Crosses Plans
Authors: A RAJARATHINAM , Adhira S.V , Ghosh D.K. 
Published: June 2021

Abstract
In this paper Complete Diallel Crosses (CDC) plan is constructed using two Balanced Incomplete Block Designs and the Galois field with the same set of parametersI. The designs were isomorphic on each other and the crossing is made between the lines. The analysis of CDC plans to estimate the general combining ability (GCA) effects and specific combining ability (SCA) effects were excluded from the model. The efficiency value of the constructed CDC plan is tends to 1, and universally optimum when v is very large. The construction is also illustrated with the suitable example.
Trade of Economically and Physically Scarce Virtual Water
Authors: Vallino Elena , Ridolfi Luca , Laio Francesco 
Published: June 2021

Abstract
The virtual water (VW) trade associated to food is composed by the quantity of water utilized for the production of the crops exchanged on the global market. In assessing a country’s water abundance or scarcity when entering the international VW trade, scholars consider only physical water availability, neglecting economic water scarcity, that indicates situations in which socio-economic obstacles impede the productive use of water. We weight the global VW trade associated to primary crops with a newly proposed composite water scarcity index (CWSI) that combines physical and economic water scarcity. Almost half of VW volumes is exported from countries with a higher CWSI than the one of the destination country. Such unfair routes occur both from low- to high-income countries and among low- and middle-income countries themselves. High-income countries have a predominant role in import of CWSI-weighted VW, while low- and middle-income countries dominate among the largest CWSI-weighted VW exporters. For many of them economic water scarcity dominates over physical scarcity. The application of the CWSI elicits also a status change from net exporter to net importer for some wealthy countries and viceversa for some low- and middle-income countries. The application of CWSI allows one to quantify to what extent VW exchanges flow along environmentally and economically unfair routes, and it can inform the design of compensation policies.
Refractory Craniopharyngioma: Successful Treatment with LINAC Based Stereotactic Radio surgery (SRS): First Case in Nepal
Authors: Thakur Subhash , Yadav Birendra , Nagamuthu Karthik , Chawla Saloni , Dubey Amit 
Published: June 2021

Abstract
Purpose: To present first case of refractory craniopharyngioma treated successfully with SRS in Nepal. Background: Craniopharyngioma is a benign tumor, which progresses slowly and compresses the pituitary gland and nearby structures. First line of treatment is surgery followed by adjuvant radiotherapy as complete resection is usually not feasible. Here, we are reporting a case of recurrent craniopharyngioma treated with LINAC based SRS. Case Presentation: A 43 years old man diagnosed case of craniopharyngioma in May 2019. He underwent left pterional craniotomy and subtotal resection of tumor and kept on observation. He developed symptomatic as well as radiological recurrence in July 2020. Second debulking was not possible, so we did SRS on 23rd August 2020; 14Gy Dose was delivered to gross tumor volume. Six months after SRS, Patient is doing well.Conclusions: LINAC based SRS is a frameless, non-invasive and safe procedure with excellent clinical outcomes for recurrent or residual craniopharyngioma.
Acupuncture combined with traditional Chinese medicine for allergic rhinitis: A protocol for systematic review and meta-analysis
Authors: Yan Le , Gou Haocheng , Feng Jun , Dai Lintong 
Published: June 2021

Abstract
Background
Allergic rhinitis (AR) is a prevalent yet underappreciated inflammatory disorder of nasal mucosa, which is characterized by pruritus, sneezing, rhinorrhoea, and nasal congestion, some studies have pointed out that if combine Traditional Chinese medicine (TCM) with acupuncture, which can enhance the effect of acupuncture and moxibustion. However, safety and efficacy of acupuncture combined with traditional Chinese medicine for treating allergic rhinitis remain largely uncertain. In our study, we will perform the first systematic review and meta-analysis to explore the effectiveness and safety of acupuncture combined with TCM for AR.
Methods
We will search the randomized controlled (RCT) literatures involving acupuncture combined with TCM for treating AR in seven electric databases, including PubMed, Web of science, EMBASE, the Cochrane library, Chinese National Knowledge Infrastructure (CNKI), Chinese Biomedical Literature Database (CBM), WanFang Database. We will define the total effective rate or cure rate, and recurrence rate as the primary outcomes. the rhinoconjunctivitis quality of life questionnaire (RQLQ) score, symptom score (nasal congestion, snot, sneezing) will be regarded as the secondary outcomes. Quality assessment of included studies will be independently performed according to the Cochrane Risk of Bias tool. Meanwhile, the level of evidence for results will be assessed by using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) method. All analysis will be conducted by using the RevMan software V5.4.
Conclusion
The conclusion of this study will confirm safety and efficacy of acupuncture combined with TCM in the treatment of allergic rhinitis, which can provide new evidence to guide appropriate interventions on AR with acupuncture combine with TCM in future.
Systematic review registration:
PROSPERO CRD42021247621
Sex-specific effects of neonatal progestin receptor antagonism on juvenile social behavior in rats.
Authors: Forbes-Lorman Robin M 
Published: June 2021

Abstract
Developing mammals are exposed to progesterone through several sources; however, the role of progesterone in early development is not well understood. Males express more progestin receptors (PRs) than females within several brain regions during early postnatal life, suggesting that PRs may be important for the organization of the sex differences in the brain and behavior. Indeed, previous studies showed cognitive impairments in male rats treated neonatally with a PR antagonist.
In the present study, we examined the role of PRs in organizing juvenile behaviors. Social play behavior and social discrimination were examined in juvenile male and female rats that had been treated with CDB, a PR antagonist, during the first week of postnatal life. Interestingly, neonatal PR antagonism altered different juvenile behaviors in males and females. A transient disruption in PR signaling during development had no effect on social discrimination but increased play initiation and pins in females. These data suggest that PRs play an important role in the organization of sex differences in some social behaviors.
Mapping the Aspergillus niger metabolite biomarkers for in situ and early evaluation of table grapes contamination
Authors: Belinato João Raul , Costa Carina Pedrosa , Almeida Adelaide , Rocha Silvia , Augusto Fabio 
Published: June 2021

Abstract
Aspergillus niger volatilome was recently explored using advanced gas chromatography tools tandem with multivariate analysis, which allowed to propose a molecular biomarker pattern for this fungus. A. niger is a ubiquitous fungus responsible for food contamination, being reported as one of the main agents of the black mold disease, a serious post-harvest pathology of table grapes. In this work the metabolite pattern already proposed was tested in three different conditions, i.e., by using : (i) 1 day of growth time for A. niger cultures; (ii) 1 day of growth time through A. niger cultures obtained from previously contaminated grapes and iii) in situ SPME approach directly on previously contaminated table grapes with A. niger. Supervised multivariate analysis was performed which revealed that after 1 day of inoculation it was possible to detect the A. niger biomarkers, which allows to infer its presence. Furthermore, the follow-up of this set of metabolites showed that they can be employed to confirm the presence of the pathogen in two varieties of table grapes. The results obtained confirm the potential applicability of the pattern of A. niger biomarkers to early detect the fungi (after 1 day of contamination) and also may be further explored for access food susceptibility to fungi contamination, based on a direct analysis of food item and taking advantage of the high sensitivity of the GC×GC-ToFMS.
Noname manuscript No. (will be inserted by the editor) COVID-19: visualizing peaks and waves in recorded cases across the globe
Authors: Dayal Vikram 
Published: June 2021

Abstract
COVID-19 has affected different parts of the globe in waves. Yet, waves are not specifically defined. Using a simple and transparent approach, I provide a bird’s-eye view of waves of recorded cases of COVID-19 at different locations across the globe. Using a widely available dataset, I compile and visualize the peak size and number of waves for over 150 locations, with a population of at least a million each. Most locations experienced one to three waves. Whether the waves increased or decreased in size within locations varies. I have created a Shiny app that helps the reader interact with the data graphs.
Morphological and molecular characterisation of Tripylina gorganensis from the Slovak Republic as a contribution to the redescription of the species
Authors: Renčo Marek , Rybarczyk-Mydłowska Katarzyna , Flis Łukasz , Kubicz Magdalena , Winiszewska Grażyna 
Published: June 2021

Abstract
Specimens of Tripylina gorganensis, collected from a natural beech forest in Slovak Republic, are described and illustrated. These nematodes were initially identified as an undescribed species, morphologically similar to Tripylina gorganensis described from Iran. An important feature distinguishing both species was the presence of post-vulval uterine sac (PUS) in specimens from Slovak Republic, which, according to the original description (Asghari et al., 2012), was absent in Tripylina gorganensis. However, a careful re-examination of type specimens performed in this study revealed that T. gorganensis also has the post-vulval uterine sac. Consequently, the findings of the morphological and molecular studies performed on the Slovak population and observations on the type material contribute to the redescription of T. gorganensis.
Heat and water flux modeling in an earth dam
Authors: Kumar Sushant , Sahu A. K. , Kumar Munendra 
Published: June 2021

Abstract
This study aims to identify the water flux in an earth dam using heat flux due to convection. Sixteen earth dam models were constructed in a hydraulic flume by varying geometrical and flow input parameters to identify heat and water flux. Homogeneous as well as earth dams with clay cores were built in a hydraulic flume. Temperature measurements were done to calculate heat flux in the experimental model. A finite element model of the earth dam using Seep/w was developed to obtain water flux, while temp/w was used to obtain heat flux. These results were used as input in Temp/w and Seep/w in Geostudio 2020. Significant reduction of the heat and water flux was seen while comparing the homogeneous models with central impervious core models. An increase in the heat and water flux was observed on increasing the downstream filter's length, longitudinal slope, and vice versa with the upstream slope and the thickness of the clay core. Comparing fluxes in a homogeneous dam model (model 1) with the clay core model (model 9) with top width 2.4 m and bottom width 18 m in model 9, both water flux and heat flux were reduced by 78.46%. While comparing it with model 10, with bottom core width of 18 m and top core width of 1.9 m, both water flux and heat flux reduced by 77.72%. Heat flux measurements were found to be a valuable alternative to detecting water flux and seepage in an earth dam at a reduced cost.
“FALTÔMETRO”: ESTRATÉGIA PARA O ENFRENTAMENTO DO ABSENTEÍSMO NO ÂMBITO DA ATENÇÃO BÁSICA
Authors: Tatiane Alves da Silva Maria , Rufino Barbosa da Silva Elaine , Ranielli da Costa Nayara , Barbosa da Silva Júnior Valdecir , De Oliveira Silva Sousa Fabiana 
Published: June 2021

Introdução: A garantia de um acesso universal, integral e equânime é um dos desafios da Atenção Básica, onde o absenteísmo se configura como obstáculo e, ao mesmo tempo, um analisador sobre a organização do cuidado do serviço de saúde. Dessa forma, necessitando de intervenções para o enfrentamento. Objetivo: Narrar a experiência da construção do “Faltômetro” e refletir sobre o desafio de implementar novas estratégias para o enfrentamento de antigos problemas nos serviços de saúde. Metodologia: Trata-se estudo descritivo do tipo relato de experiência, realizado numa Estratégia de Saúde da Família (ESF), no município de Vitória de Santo Antão - PE, com o Núcleo Ampliado de Saúde da Família e Atenção Básica (NASF-AB) de referência, entre junho e outubro de 2019. A experiência foi realizada em três etapas: monitoramento das demandas do NASF-AB; construção do “Faltômetro” e sala de espera com os usuários. Resultados: Por meio da experiência, foi identificada a fragilidade no registro de faltas; a importância do Agente Comunitário de Saúde (ACS); a necessidade de identificação das causas das faltas; e a necessidade de repensar a organização do processo de trabalho. Conclusões: O “Faltômetro” e a sala de espera foram estratégias fundamentais para o debate sobre o absenteísmo no âmbito da Atenção Básica. No entanto, faz-se necessário o desenvolvimento de processos de Educação em Saúde com a população, permitindo um diálogo horizontal, para a compreensão das possíveis causas das faltas. Além disso, os profissionais em saúde necessitam romper com o discurso de culpabilização dos usuários, reconhecendo a existência de barreiras de acesso no território.
Palavras-Chave: Absenteísmo; Atenção Primária à Saúde; Educação em saúde; Sistema Único de Saúde.
SERVIÇO DE SAÚDE ESCOLAR: EVIDÊNCIAS DA LITERATURA
Authors: Brandão de Araújo Karla , Oliveira Abinader Erika , Brandão de Araújo Vanessa , Brandão de Castro Jamilly , De Souza Brandão Karem 
Published: June 2021

RESUMO
Introdução: Ações em saúde, no âmbito escolar, pré-dispõe os indivíduos a adotarem medidas de proteção quanto a sua saúde reduzindo fatores de risco na vida adulta corroborando para melhor qualidade de vida. Objetivo: Pesquisar as evidências científicas sobre as ações de saúde ofertadas no ambiente escolar. Metodologia: Estudo descritivo, com abordagem qualitativa que através de revisão integrativa da literatura investigou as evidências sobre o objeto deste estudo utilizando as bases: LILACS e SCIELO. A coleta dos dados ocorreu em julho de 2020, aos pares, considerando o recorte temporal de cinco anos (2015 à 2020) nos idiomas português e inglês. A estratégia de busca foi formulada utilizando os descritores controlados “serviços de saúde escolar” e “promoção da saúde” que foram combinados entre si através do operador booleano AND. Resultados: Foram encontrados 1603 artigos que após uso de critérios de elegibilidade, restaram 05 na composição da amostra final. Da análise do conteúdo foi evidenciado as lacunas quanto promoção da saúde no ambiente escolar. Conclusões: os serviços de saúde no âmbito escolar são realizados através de ações pontuais, geralmente motivadas por ações sanitaristas com modelo campanhista. Foi evidenciado a necessidade de educação permanente para capacitação dos profissionais.
Palavras-Chave: Serviços de saúde escolar, Promoção da Saúde, Equipe de assistência ao paciente.
EFICÁCIA DE OLÉOS VEGETAIS NO CONTROLE DO BIOFILME DENTAL: REVISÃO INTEGRATIVA
Authors: Gaia de Oliveira Suila , Tupinambá Emmi Danielle 
Published: June 2021

Introdução: A terapia de bochecho com óleos vegetais é uma cultura tradicional na Índia com intuito de prevenir afecções bucais, como cárie e doença periodontal. Atualmente, com as mudanças nos padrões alimentares da sociedade, tem-se empregado com maior valor o uso de óleos naturais, já que estudos demonstram sua importância para saúde. Objetivo: Esta revisão integrativa teve como objetivo selecionar evidências que mostrassem a utilização de óleos vegetais, com ação antimicrobiana, no controle do biofilme dental. Metodologia: O levantamento bibliográfico foi realizado nos meses de julho e agosto de 2020, por meio de pesquisa por via eletrônica, consultando-se o banco de dados Pubmed e SciELO (Scientific Electronic Library Online). Foram utilizados os descritores: Óleos vegetais, agentes antimicrobianos, Placa dental, Odontologia preventiva e Odontologia, os descritores foram usados separadamente e em cruzamento com o operador boleano AND. Utilizou-se os seguintes critérios de inclusão: Estudos clínicos, artigos completos e disponíveis gratuitamente, publicados no período de 2010 a 2020 em português e/ou inglês, e indexados nas bases de dados já citadas. Foram excluídos os trabalhos de conclusão de curso, dissertações, teses, livros e capítulos de livros, além de artigos duplicados e que não abordaram o tema do estudo. Resultados: Foram previamente selecionados 10 artigos indexados após a leitura do título, 09 na base de dados Pubmed e 01 na base Scielo. Após a leitura do resumo, 04 artigos atenderam os critérios de inclusão e 06 artigos foram descartados, sendo 05 artigos da Pubmed e 01 da Scielo. Conclusões: Os artigos analisados mostraram eficácia na utilização de óleos vegetais no controle do biofilme dental, sendo esses aplicados clinicamente, não mostrando prejuízo aos participantes e indicados como coadjuvante na manutenção da saúde bucal.