bluuebunny/crossref_metadata_2025_split huggingface dataset:
Patient perceptions of surgical telehealth consultations during the COVID 19 pandemic in Australia: Lessons for future implementation
Authors: Wiadji Elvina , Mackenzie Lisa , Reeder Patrick , Gani Jonathan S. , Ahmadi Sima , Carroll Rosemary , Smith Stephen , Frydenberg Mark , O'Neill Christine J. 
Published: June 2021

AbstractIntroductionPrior studies of telehealth report high levels of patient satisfaction, but within carefully selected clinical scenarios. The COVID‐19 pandemic led to telehealth replacing face‐to‐face care for many surgical consultations across a variety of situations. More evidence is needed regarding patient perceptions of telehealth in surgery, in particular, exploring barriers and facilitators associated with its sustained implementation beyond the pandemic.MethodsSurvey invitations were emailed to a convenience sample of surgical patients by their surgeon following a telehealth consultation during the COVID‐19 pandemic. Surgeons were recruited from a sample (n = 683) who completed a survey on telehealth (distributed via email to all Australian Fellows of the Royal Australasian College of Surgeons). Mixed methods analysis was performed of the patient survey data.ResultsA total of 1166 consultations were captured: 50% routine reviews, 17% initial appointments and 20% post‐operative reviews. Video‐link was used in 49% of consultations. The majority of patients (94%), were satisfied with the quality of their surgical telehealth consultation and 75% felt it delivered the same level of care as face‐to‐face encounters. Telehealth was convenient to use (96%) and led to cost savings for 60% of patients. When asked about future appointment preferences after the pandemic, 41% indicated they would prefer telehealth (24% video‐link and 17% telephone) over face‐to‐face appointments. There was a perception by patients that telehealth consultation fees should be less than face‐to‐face consultation fees.ConclusionPatient satisfaction with surgical telehealth consultations is high. Barriers to more widespread implementation include financial, clinical appropriateness, technical and confidentiality concerns.
It's not you, it's me: a descriptive study of patient complaints and surgeon understanding
Authors: McSweeney William , Leaning Matthew , Dastouri Darius , Parkinson Debra , Hendahewa Rasika 
Published: June 2021

AbstractBackgroundPatient complaints are an underutilized and under‐addressed issue in general surgery. They represent a unique sphere of interaction for surgeons and patients to understand motivations and failures in the delivery of healthcare. The aims of this study were to identify motivators of patient complaints and understand surgeon's awareness of this issue.MethodsA retrospective review of patient complaint data in a single regional general surgical department was undertaken between the periods October 2017 to June 2020 and June 2018 to October 2020 relating to patient demographics and subject of complaint. Secondly, an anonymous survey was conducted across the same department and results tabulated by seniority.ResultsTwo hundred and nineteen complaints were received during the study period. One hundred and thirteen were made by patients, while 56 were made by family members. One hundred and fifty‐nine complaints were related to an inpatient episode of care, and 152 were made in writing. The majority of complainants were female, with a mean age of 52. The most common reason for complaint was “treatment” (n = 102), followed by communication (n = 48), and humaneness/caring (n = 44). Consultant surgeons and surgical trainees placed communication, humaneness/caring, and professionalism as most likely to incite complaints, while interns were more likely to prioritize other measures such as patient healthcare rights and medications.ConclusionPatient complaints remain a relatively under‐utilized resource in addressing the downfalls of general surgical departments. This study reports patient demographics that are congruent with the literature and highlights that surgeons prioritize many non‐technical skills in the maintenance of the doctor‐patient relationship, in contrast to preconceptions.
Independent primary cutaneous and mammary apocrine carcinomas with neuroendocrine differentiation: Report of a case and literature review
Authors: DeCoste Ryan C. , Carter Michael D. , Barnes Penelope J. , Andea Aleodor A. , Wang Min , Rayson Daniel , Walsh Noreen M. 
Published: June 2021

AbstractCutaneous apocrine carcinomas share common features with their counterparts in the breast; hence, metastatic mammary carcinoma must be excluded before such lesions can be designated primary cutaneous neoplasms. Primary tumors from either source rarely exhibit neuroendocrine differentiation. We report a case of a 72‐year‐old female with a painless 1.2‐cm scalp nodule. An incisional biopsy revealed dermal involvement by an invasive apocrine carcinoma juxtaposed to a benign apocrine cystic lesion. Immunohistochemically, the carcinoma expressed neuroendocrine proteins including synaptophysin, chromogranin, and CD56. A primary cutaneous apocrine carcinoma with neuroendocrine differentiation was favored, but additional investigations to exclude breast origin were recommended. These revealed a 1.1‐cm nodule in the right breast, which proved to be an invasive ductal carcinoma, morphologically and immunophenotypically similar to the scalp lesion. This confounded the case, yet factors militating against metastatic breast carcinoma to skin included (a) the small size of the mammary tumor, (b) absence of other metastatic disease, and (c) juxtaposition of the scalp carcinoma to a putative benign precursor. Molecular studies were undertaken to resolve the diagnostic quandary. Single nucleotide polymorphism microarray analysis revealed distinct patterns of chromosomal copy number alterations in the two tumors, supporting the concept of synchronous and unusual primary neoplasms.
Interventions involving own treatment choice for people living with coexisting severe mental illness and type 1 or 2 diabetes: A scoping review
Authors: Zabell Vicki , Rønne Sabrina T. , Høgsgaard Ditte , Jørgensen Rikke , Gæde Peter H. , Arnfred Sidse M. 
Published: June 2021

AbstractAimThe objective of this scoping review was to summarize, understand and provide an overview of the empirical literature on interventions involving own treatment choice for people with coexisting diabetes (type 1 and 2) and severe mental illness (SMI).MethodsThis scoping review undertook a systematic literature assessment. Searches were performed in MEDLINE, Embase, PsycINFO, Web of Science, CINAHL, the Cochrane Library and grey literature (OpenGrey, Google Scholar and Danish Health and Medicine Authority databases). Publications from 2000 to July 2020 were of interest. Studies were included if they involved the users’ own choice of treatment. Included studies: RCT, intervention, cohort and case‐based studies.ResultsA total of 4320 articles were screened, of which nine were included. The review identified eight studies from the United States and one from Canada testing different interventions for people with SMI and diabetes (one diabetes education program, five randomized controlled trials, one retrospective cohort study, one naturalistic intervention program and one case vignette). The interventions described in the nine articles involved service users, the majority incorporated individualized healthcare plans, and all interventions were based on multidisciplinary teamwork.ConclusionsResearch in the area is limited. Care management interventions tend to focus on a single condition, paradoxically excluding SMI during enrolment. Interventions aimed at people with both conditions often prioritize one condition treatment leading to an unbalanced care.
Epigenetic regulation and signalling pathways in Merkel cell development
Authors: Oss‐Ronen Liat , Cohen Idan 
Published: June 2021

AbstractMerkel cells are specialized epithelial cells connected to afferent nerve endings responsible for light‐touch sensations, formed at specific locations in touch‐sensitive regions of the mammalian skin. Although Merkel cells are descendants of the epidermal lineage, little is known about the mechanisms responsible for the development of these unique mechanosensory cells. Recent studies have highlighted that the Polycomb group (PcG) of proteins play a significant role in spatiotemporal regulation of Merkel cell formation. In addition, several of the major signalling pathways involved in skin development have been shown to regulate Merkel cell development as well. Here, we summarize the current understandings of the role of developmental regulators in Merkel cell formation, including the interplay between the epigenetic machinery and key signalling pathways, and the lineage‐specific transcription factors involved in the regulation of Merkel cell development.
Consumers’ purchase behaviour and green marketing: A synthesis, review and agenda
Authors: Sharma Ajai Pal 
Published: June 2021

AbstractThe study presents an overview of green marketing and the gap between attitude and actual purchase behaviour of consumers towards green products. A total of 232 studies have been analysed using a systematic review to develop a green purchase decision‐making model. A thematic analysis helped in the identification of three major themes namely; personal factors affecting green purchase; green purchase; and green marketing mix. The concern for eco‐environment, eco‐labelling, past experiences and perceived usefulness have been identified as major influencers of green consumer behaviour. Lack of environmental knowledge, price, perceived associated risks, organizational image, trust, and willingness to pay has been identified as barriers, creating a gap between attitude and actual purchase behaviour of consumers towards green products. On the basis of analysis, a green purchase decision model has been proposed and also potential areas of future research have been suggested.
The creation and implementation of advanced practice nursing in France: Experiences from the field
Authors: Colson Sébastien , Schwingrouber Jocelyn , Evans Catherine , Roman Christophe , Bourriquen Maryline , Lucas Guillaume , Mellinas Marie , Brunet Philippe , Cermolacce Michel , Chinot Olivier , Mayen Sandrine , Berbis Philippe 
Published: June 2021

AimThis paper describes the characteristics of the new advanced practice nursing roles in France, as well as their challenges and perspectives, and compares the French model with the recommendations of the International Council of Nurses.BackgroundAdvanced practice nursing is particularly well established in English‐speaking countries. Since 2018, France has become the second French‐speaking region to legalize and regulate advanced practice nurses.Source of evidenceThe International Council of Nurses and French government websites, and scientific databases (PubMed, CINALH, Cochrane Library) were explored. Feedback from French nursing academics was also requested.DiscussionThe advanced practice nursing model in France is described according to the scope and conditions of professional practice. The educational program leads to a State diploma with master’s degree, which it is mandatory to be a registered nurse. Remuneration depends on the sector of practice in the public hospital, primary care or private sector. Although there is no national strategy for the implementation of advanced practice nursing roles, research projects are being initiated to guide and evaluate the practice. Based on concordance analysis with the recommendations of the International Council of Nurses, the French advanced practice nursing model appears to be similar to the nurse practitioner model.ConclusionAdjustments in the scope of practice and education can be expected as the implementation of these roles is evaluated.Implications for nursing practiceThis is a historical evolution of the nursing profession in France, for which communication with patients and healthcare professionals is essential.Implications for nursing policyThe implementation of advanced practice nursing roles in clinical settings requires the development of national strategies to support initiatives and ensure the sustainability of these roles.
CEO cultural heritage and the pricing of audit services
Authors: Pham Anh Viet , Pham Mia Hang , Truong Cameron 
Published: June 2021

AbstractWe construct preferences toward risk and uncertainty as reflected in the cultural heritage of chief executive officers (CEOs) managing public firms in the United States. We demonstrate that auditors take into account the cultural traits of CEOs in the pricing of their audit services. We also show that CEO cultural heritage is associated with a firm's misreporting, internal control weakness, and accounting conservatism. The results are robust to controlling for other known attributes of CEOs, firm characteristics, and corporate governance. Our study contributes to research on corporate risk culture, CEO characteristics, and determinants of the pricing of audit services and financial reporting quality.
Microstructure of paneer prepared by automated pressing technique
Authors: Sinha Chitranayak , Manjunatha M.  , Jayaraj Rao K.  , Sinha Pushpanayak , Kumari Khushbu , G. Kumar Mahesh , Dabas Jitender Kumar 
Published: June 2021

AbstractIn this study, paneer was prepared by conventional method as well as by employing an automated pressing equipment and microstructure of paneer samples was studied by scanning electron microscopy. Further, pneumatic pressing of the hot coagulum was carried out at different pressures (2.5, 3.0, and 3.5 kg cm−2) and time durations (10, 12.5, and 15 min) using a semi‐automated microprocessor based pneumatic pressing unit. It was found that the microstructure of paneer comprised mainly of continuous medium of casein matrix in which micro‐pores were distributed. However, differences were observed in the way the curd particles were fused during the pressing process of paneer manufacture. Paneer obtained from the automated press was found to possess more uniformity than the one prepared by conventional method. This was attributed to more uniform pressure applied by the automated technique. Further, porosity values were correlated with the openness observed in the microstructure of paneer. It was found that at an optimized pressure and time combination, paneer had a more uniform structure along with porosity than conventionally made one. The dependence of the paneer properties on the pressure and pressing time was well fitted to polynomial quadratic model which showed influence of pressure applied is greater than the time of pressing.Practical ApplicationsThe SEM imaging of paneer prepared by automated pneumatic pressing based technique could be very useful in analyzing the microstructure which influences the texture and amount of water retention. Small to medium scale paneer manufacturers could very well utilize the automated pneumatic pressing technique to produce paneer of optimum texture and adequate amount of moisture. Paneer manufacturers of small to medium scale could very well utilize this pressing technique to increase their income at farm level.
Care dependency of patients and residents at the end of life: A secondary data analysis of data from a cross‐sectional study in hospitals and geriatric institutions
Authors: Schüttengruber Gerhilde , Halfens Ruud J. G. , Lohrmann Christa 
Published: June 2021

AbstractAims and objectivesThe holistic care dependency concept can be applied to gain comprehensive insights into individuals’ care needs in the end‐of‐life (EoL) phase. This study was carried out to measure and characterise the “care dependency” phenomenon in this phase and to obtain deeper knowledge about this phenomenon.BackgroundThe end of a human life is often characterised by a physical decline, often implying that a high amount of care is needed. Non‐malignant diseases can develop unpredictably; therefore, it is difficult to detect the onset of the EoL phase.DesignData were collected in a cross‐sectional multicentre study, using the Austrian Nursing Quality Measurement 2.0.MethodsDescriptive and multivariate statistical methods were used. Care dependency was measured with the Care Dependency Scale (CDS). The study follows the STROBE guideline.ResultsTen per cent (n = 389) of the sample (N = 3589) were allocated to “a pathway for management of patients at the end of life.” The patients and residents in the EoL phase are significantly older and more often diagnosed with dementia, and circulatory system and musculoskeletal system diseases. Of these patients, 60% were care dependent completely or to a great extent. Dementia and age represent main influencing factors that affect the degree of care dependency at the end of life.ConclusionOur results show that the “typical” EoL patient or resident is female, old and affected by dementia and/or circulatory system diseases. Dementia and age were identified as main factors that contribute to very high care dependency.Relevance to clinical practiceThe measurement of care dependency may support the identification of special care needs in the EoL phase. Gaining deeper knowledge about the care dependency phenomenon can also help healthcare staff better understand the needs of patients with non‐malignant conditions in their last phase of life.
High‐frequency trading: Definition, implications, and controversies
Authors: Zaharudin Khairul Zharif , Young Martin R. , Hsu Wei‐Huei 
Published: June 2021

AbstractHigh‐frequency trading (HFT) is an important component of stock market activity on major exchanges. In the United States, HFT contributed approximately 52% of total equity trading in 2018, with an estimated value of more than US$17 trillion. However, to date, there is no standard definition of HFT, and how it is perceived or viewed depends on the underlying criteria set by regulators. The lack of a uniform identification for HFT leads to problems, such as research complications, that lead to somewhat conflicting conclusions as to the effect of HFT on equity markets in general and the market microstructure in particular. This article presents a survey of the definitions, measurements, mechanisms, empirical evidence, and relevant controversies and issues pertaining to HFT.
Influence of the median lobe on the results at 4 years of the prostate vaporization by GreenLight laser
Authors: Vanalderwerelt Victor , Pradère Benjamin , Grevez Tristan , Faivre D'Arcier Benjamin , Bruyère Franck 
Published: June 2021

AbstractObjectiveThe aim of this study was to examine the influence of a median lobe (ML) on complications and functional results after 4 years of GreenLight photoselective vaporization of the prostate (PVP).MethodsAll men undergoing GreenLight PVP for benign prostatic hyperplasia were included in the baseline analysis and followed prospectively. Two groups were formed according to the presence or absence of the prostatic ML. Complications classified according Clavien and Dindo and functional results (International Prostate Symptom Score [IPSS], quality of life, maximum urinary flow rate [Qmax], and postvoid residual [PVR]) were evaluated with 4 years of follow‐up. The pre‐ and postoperative data were compared by a chi‐square test (χ2) for the qualitative variables and by a Student t test for the quantitative variables.ResultsA total of 432 patients (172 with ML and 260 without ML) were included prospectively from September 2005 to October 2013. The initial populations were comparable. At 4 years of follow‐up, the improvement in mean IPSS was significantly greater for patients with ML at 6, 12, 24, and 48 months. The improvement in Qmax was significantly greater for patients with ML at 1, 6, 24, and 48 months. There was no significant difference between the two groups concerning the PVR reduction, the occurrence of complications, the level of average prostate‐specific antigen, and the average ultrasound volume at 4 years.ConclusionThere is a clearer and longer‐lasting improvement in urinary symptoms in patients with prostatic ML. The indication of PVP in those patients seems to be excellent, with good results persisting at 4 years.
Bayesian Skyline Plots disagree with range size changes based on Species Distribution Models for Holarctic birds
Authors: Miller Eleanor F. , Green Rhys E. , Balmford Andrew , Maisano Delser Pierpaolo , Beyer Robert , Somveille Marius , Leonardi Michela , Amos William , Manica Andrea 
Published: June 2021

AbstractDuring the Quaternary, large climate oscillations impacted the distribution and demography of species globally. Two approaches have played a major role in reconstructing changes through time: Bayesian Skyline Plots (BSPs), which reconstruct population fluctuations based on genetic data, and Species Distribution Models (SDMs), which allow us to back‐cast the range occupied by a species based on its climatic preferences. In this paper, we contrast these two approaches by applying them to a large data set of 102 Holarctic bird species, for which both mitochondrial DNA sequences and distribution maps are available, to reconstruct their dynamics since the Last Glacial Maximum (LGM). Most species experienced an increase in effective population size (Ne, as estimated by BSPs) as well as an increase in geographical range (as reconstructed by SDMs) since the LGM; however, we found no correlation between the magnitude of changes in Ne and range size. The only clear signal we could detect was a later and greater increase in Ne for wetland birds compared to species that live in other habitats, a probable consequence of a delayed and more extensive increase in the extent of this habitat type after the LGM. The lack of correlation between SDM and BSP reconstructions could not be reconciled even when range shifts were considered. We suggest that this pattern might be linked to changes in population densities, which can be independent of range changes, and caution that interpreting either SDMs or BSPs independently is problematic and potentially misleading.
Critical appraisal of different triggering pathways for the pathobiology of pemphigus vulgaris—A review
Authors: R Hannah , Ramani Pratibha , Tilakaratne WM , Sukumaran Gheena , Ramasubramanian Abilasha , Krishnan Reshma Poothakulath 
Published: June 2021

AbstractPemphigus vulgaris is an autoimmune blistering disease with an increased potential for mortality. The epithelium is key in understanding the pathobiology as it is specialized to perform functions like mechanical protection, immunological defense, and proprioception. In order to perform these array of functions, epithelial integrity is important. This integrity is maintained by a host of molecules which orchestrate the ability of the keratinocytes to function as a single unit. Desmoglein 3 antibodies formed in genetically susceptible individuals are known to cause the disruption of the intact oral mucosa leading to the formation of blisters in pemphigus vulgaris patients. However, there are underlying complex triggering pathways leading to the clinical disease. The aim of the review is to congregate and critically appraise the various triggering pathways which contribute toward the pathobiology of pemphigus vulgaris. Articles relevant to the pathobiology of pemphigus vulgaris were identified from various search databases till the year 2020. The pathogenesis of pemphigus vulgaris is complex, and it involves an in‐depth understanding of the various predisposing factors, provoking factors, and progression mechanisms. Congregation of the various triggering pathways will open our minds to understand pemphigus vulgaris better and in turn develop a reliable treatment in the near future.