bluuebunny/crossref_metadata_2025_split huggingface dataset:
DEVELOPMENT OF QUALITY INDICATORS FOR PHARMACEUTICAL CARE PERFORMANCE ASSESSMENT IN NIGERIAN COMMUNITY PHARMACIES: A DELPHI PANEL
Authors: NNEOMA OKPALANMA , OBINNA EKWUNIFE 
Published: February 2021

Objective: This study aimed to develop quality indicators for assessing pharmaceutical care performance in the Nigerian community pharmacies.
Methods: We searched for existing quality indicators through an extensive literature review. The identified quality indicators consisted of thirty-four items in 10 core components. The Delphi method was used to arrive at a consensus on quality indicators for assessing pharmaceutical care performance in the Nigerian community pharmacies by surveying a panel of experts. There were 3 rounds of the Delphi panel conducted by consulting a panel of 10 experts in pharmaceutical care practice. A mean score>3.5, median>3.5, an absolute value between the median and mode<1.00 was used to establish consensus on the quality indicators for assessing pharmaceutical care performance in the Nigerian community pharmacies.
Results: Ten studies met the inclusion criteria. A list of 33 quality indicators comprising of 10 core components emerged from the extensive literature review. They included quality management, documentation of care, communication with the patient, management of clinical risk in pharmacy, compounding, dispensing and patient care, follow-up of pharmacotherapy counselling, drug inventory and stocking, training of pharmaceutical staff. At the end of the round three votings, 24 statements of the quality indicator reached consensus in nine core components: quality management (5), continuity of care (1), communication with patients (3), clinical risk management (5), dispensing (1), follow-up of pharmacotherapy (3), counselling (1), logistics (3), training of pharmacy staff (2).
Conclusion: This study developed a set of 24 quality indicators for assessing pharmaceutical care performance in community pharmacies in Nigeria.
THE EFFECT OF HEALTH EDUCATION AS NON-PHARMACOLOGICAL THERAPY ON PHYSICAL FITNESS, BLOOD CHEMISTRY AND BRAIN FUNCTION AMONG SENIOR CITIZEN IN BOTH RURAL AND URBAN AREAS OF BALI, INDONESIA
Authors: ADIATMIKA I PUTU GEDE , TERASAWA KOJI , MARUO SUCHINDA JARUPAT , NAKADE KEISUKE , WATANABE TOSHIAKI , TERASAWA SAIKI , KOBAYASHI TOSHIE , ZHANG YONG , NAKAJIMA KOKI , SASAMORI FUMIHITO 
Published: February 2021

Objective: The population of senior citizens has increased and needs more care for the quality of life. Health education is a non-pharmacological therapy to improve physical fitness, blood chemistry and brain function. This research was performed to evaluate the effect of health education on the physical fitness, blood chemistry and brain function of senior citizens in rural and urban Bali.
Methods: A total of 60 people aged 67.9±1.2 y were recruited from Tabanan, Indonesia, and 72 people aged 67.3±0.6 y were recruited from Denpasar, Indonesia. The health education program lasted 8 mo, used Japanese-style healthcare modified for the Balinese culture, and measured physical fitness, blood chemistry, and brain function before and after the educational period.
Results: The average number of steps in Tabanan was 4247.2±98.9, and those in Denpasar were 4336.1±102.4. The weight and waist circumference were not significantly different between the Tabanan and Denpasar samples. The physical fitness of senior citizens in Tabanan and Denpasar improved significantly. Blood chemistry in the Tabanan sample was not significantly different after the program. In Denpasar, High-Density Lipoprotein and Low-Density Lipoprotein significantly improved. Brain function was significantly improved after the program.
Conclusion: Health education using Japanese-style healthcare programs based on Balinese culture as non-pharmacological therapy has beneficial effects on physical fitness, blood chemistry and brain function in senior citizens in both urban and rural areas in Bali, Indonesia. It is suggested that senior citizens should continue our health education program to maintain their health.
ANALYSIS OF BIO-ACTIVE COMPOUNDS PRESENT IN THE LEAVES AND STEM OF TRICHOSANTHES ROXB. USING GC-MS TECHNIQUE WITH RESPECT TO ITS ANTI-INFLAMMATORY ACTION
Authors: ARAVINDAKSHAN AGHIL SOORYA , THANGAVEL SEKAR 
Published: February 2021

Objective: Structural elucidation studies on Trichosanthes lobata ethyl acetate and methanol extracts of leaf and stem parts through Gas Chromatography-Mass Spectrometry (GC-MS) technique with respect to anti-inflammatory potential.
Methods: Extracts obtained with shade dried and powdered samples in successive solvent extraction using ethyl acetate and methanol by Soxhlet apparatus and subjected to GC-MS analysis and interpreted for its anti-inflammatory compounds.
Results: The study revealed that the extraction solvent used was able to recover compound of classes such as organic acid esters and conjugated alkaloids in larger quantities than other classes of compounds and they varied with leaf and stem and also with the polarity of solvents used. In total compounds identified, GC-MS profile of the Ethyl Acetate leaf extract of T. lobata contained 41 compounds, stem extract contained 45 compounds which have reported bioassays in PubChem. Whereas GC-MS profile of methanol leaf extract of T. lobata contained 66 compounds and stem extract contained 46 compounds having bioassay reports in PubChem. A large number of phytochemical peaks with good area percentage were found in methanolic extract. We were also able to find out potent anti-inflammatory compounds including Octanoic acid, Dodecanoic acid, Octadecane, Enoic acid, Hexanoic acid, Quinazolin-8-one, Ilicic acid, Pentadecanoic acid, Oxaspiro, Benzeneacetic acid, etc. from the extracts.
Conclusion: T. lobata contains phytocompounds against inflammation which may serve as a new drug lead of natural products origin in future and make it employable in modern pharmacological practices.
OPTIMIZATION OF ALBENDAZOLE 400 MG TABLET COMPRESSION PROCESS USING DESIGN OF EXPERIMENT (DOE) APPROACH
Authors: SILVA LUCAS PEDROSA D. A. , BOLDO EMERSON MARIO 
Published: February 2021

Objective: The present study aims to model and optimize the compression process of the Albendazole 400 mg tablets of a pharmaceutical industry production line to increase the production speed (tablets/h) while maintaining quality requirements.
Methods: The study was conducted using the Design of Experiments (DoE) methodology to identify and correlate the critical parameters during the process that affect the maintenance of the compression speed. In order to support the experiments, was tested disintegration time, average hardness, hardness variation, average weight, and friability.
Results: Was obtained that quality attributes of disintegration and friability did not generate a significant model but it has been established correlations between Fill-O-Matic speed and main compression force in the responses of weight variation, hardness, and mean hardness. It was found that the main compression force between 6 to 9 kN, the pre-compression force of 1,965 to 5,615 kN, and the speed of 55 RPM for Fill-O-Matic speed are responsible for ensuring that all quality attributes analyzed remain within the expected specification.
Conclusion: It was possible to apply the Design of Experiment (DoE) methodology in the compression process of the drug Albendazole 400 mg and to evaluate the impact of the parameters of this step on the formation of the tablet to significantly increasing the productivity of this product. The Fill-O-Matic speed parameter was the main control factor discovered in this study to maintain quality attributes.
MEASURING SUPPLY CONCENTRATION ON THE SERBIAN OIL AND OIL DERIVATES MARKET BY HERFINDAHL-HIRSCHMAN INDEX
Authors: Veselinović Milan , Radukić Snezana 
Published: February 2021

One aspect of the intensity of competition analysis of the national oil market is the measurement of the concentration of supply, to which this paper is dedicated. That is why it is not surprising that there are different interpretations of these economic categories. The analysis of these phenomena dates back to the emergence of production relations and production forces. The relaxation of regulatory measures on the national oil market has opened the space for building quality competitive relationships between the participants. Market opportunities, conditions and competition in practice are determined by concentration in the certain observed market. Competitive relations between market participants change over time. Those changes impact on concentration level of certain and well defined market, in this case the oil market of the Republic of Serbia. As the competition changes, the concentration level changes as well. This is the reason why this paper is focused on concentration level measurement and analysis. In measuring and expressing the concentration level of the certain market, many concentration indicators could be applied. Our choice was Herfindahl-Hirschman Index.
La teoría de la declaración de voluntad en el negocio jurídico:
Authors: Pinochet Olave Ruperto , Delgado Castro Jordi 
Published: February 2021

The expression of consent on the answer to a complaint has erroneously been understood as a presumed or tacit declaration of intention by the doctrine and jurisprudence. This paper discusses the main elements for a proper conceptualization of the use of the theory of the legal act to the legal process. Moreover, the paper discusses the challenging application of these concepts to Civil Procedure Reform.
¿Había espacio fiscal para enfrentar la pandemia en México? Una revisita a la sostenibilidad fiscal
Authors: Hernández Trillo Fausto 
Published: February 2021

<p>En este artículo se evalúa el espacio fiscal para enfrentar los efectos económicos adversos que provocaría la pandemia en México utilizando un ejercicio de sostenibilidad fiscal desarrollado por Talvi y Vegh (2000). Los resultados arrojan que en la actualidad no hay sostenibilidad fiscal, y que para obtenerla es necesario duplicar el superávit primario promedio de 0.71% del PIB que México ha tenido desde 2001. Sin embargo, en caso de haber introducido el plan económico propuesto por distintos organismos y analistas que ascendía a un nuevo endeudamiento de 3% del PIB, se hubiera tenido, a partir del 2021, que haber incrementado el superávit promedio en 0.74%, es decir, un monto de superávit primario de 0.03% anual adicional al faltante actualmente, cantidad asequible sobre todo para paliar los efectos de la crisis del COVID sobre la actividad económica.</p><p> </p>
La COVID-19 y su impacto en la pobreza de Ecuador: método de escenarios
Authors: Correa-Quezada Ronny , García-Vélez Diego Fernando , Álvarez-García José , Tituaña-Castillo María del Cisne 
Published: February 2021

<p>Las medidas gubernamentales adoptadas para combatir la pandemia paralizan las actividades económicas y afectan los ingresos de la población. Por lo tanto, el objetivo de esta investigación es estimar y analizar los impactos de la COVID-19 en la pobreza de Ecuador utilizando el método de escenarios. Para lo cual, a partir de los datos de la Encuesta Nacional de Empleo, Desempleo y Subempleo (ENEMDU) de 2019, se construyó siete escenarios que consideran alternativas en cuanto a la reducción de ingresos de los hogares y se calculó las tasas de pobreza, considerando el enfoque monetario y bajo la metodología utilizada por el Instituto Nacional de Estadísticas y Censos (INEC). Los principales resultados muestran que la pobreza en Ecuador podría incrementarse hasta el 27.2%, 29.2% o 34.7% si los ingresos de los hogares disminuyen en un 5%, 10% o 20% respectivamente.</p><p> </p>
Basra: the influence of territories, rich for crude oil, on the development of Iraqi governorates
Authors: Slepnev Mihail A. , Al-qatrany Anwar Sabeeh 
Published: February 2021

Introduction. The article presents the results of the analysis of changes in the planning structure of an urbanized area, addresses land use for crude oil recovery purposes in the Basra governorate, and explores the influence, produced by this activity on urban development and the environment using the city of Basra as an example. Crude oil recovery reduces the size of natural areas. The practical aspect of the scientific research entails the development of an information system designated for land management and the maintenance of databases focused on the study of urban planning tasks to ensure well-balanced development of areas, rich for crude oil in the Basra governorate with regard for a structured regional planning pattern as one of the most important objectives of Iraq. Growing residential areas, on the one hand, and expanding areas occupied by oil recovery and industrial enterprises, on the other hand, have been a relevant post-war problem since 2003. The environmental disorder, caused by substantial changes in land use, involves various disruptions, which translate into grave problems of the urban environment experienced by the governorate of Basra.
Materials and methods. Official data, submitted by the Basra administration, tables, documents and cartographic materials were used to perform this research, let alone the open source information, including maps that contain statistical calculations made using the ArcGIS10.x software package and Microsoft Excel. The co-authors also performed a retrospective analysis of the Basra territory using remote sensing, which allowed them to determine the boundaries of the city and to track its spatial transformation.
Results. The retrospective analysis has identified changes in the city borders. High economic growth, boosted by oil production and developing industrial territories, drives the need for well-balanced territories focused on sustainable development, especially in the historical part of Basra which is suffering from degradation.
Conclusions. The problem of unbalanced use of urbanized territories and environmental sustainability of cities, affected by wars and military operations, requires the development of regulations governing the delimitation of borders within the framework of a land-use plan to be developed.
The impact effect of underground trains in motion analyzed together with other factors contributing to the stress-strain state arising along the tunnel lining boundary
Authors: Mitroshin Vasiliy A. , Mondrus Vladimir L. 
Published: February 2021

Introduction. Urban expansion and compaction of urban environments trigger the need for delay-free transport communications between urban districts. An underground railway is a modern means of transport, whose construction and operation are feasible below the ground surface. However, it is a source of vibrations that negatively affect human comfort and high-tech production processes. Train speed, weight, wheel and rail defects, the geological structure of the site, subway route construction conditions, the remoteness of measuring equipment installation points are the main factors that influence the intensity of vibrations of the ground surface or building structures. The effect, produced by moving subway trains on the tunnel lining, as well as the wheel-rail junction interface are analyzed in this work.
Materials and methods. The problem of stresses, triggered by underground trains along the boundary of the tunnel lining, can be reduced to the well-known problem of a beam on an elastic foundation. MathCAD software package was used to obtain the analytical solution and diagrams.
Results. The co-authors identified the values of stresses arising along the boundary of the tunnel lining as a result of the interface between underground trains and rail junctions. Diagrams that illustrate deflections of a bending curve of an infinite beam, bending moments, and stresses arising along the boundary of the tunnel lining have been made. Values of regular stresses arising along the tunnel boundary are obtained by transforming external loads into Fourier series.
Conclusions. The data obtained as a result of the analysis are further used to solve problems of identifying the wave field in a continuous elastic medium using methods of successive wave approximations and compensating loads.
The branch and bound method applied to the construction of residential quarters
Authors: Velichkin Victor Z. , Petrochenko Marina V. , Strelets Ksenia I. , Zavodnova Evgeniya B. , Gorodishenina Anna Yu. 
Published: February 2021

Introduction. When construction works are scheduled within the framework of a project that encompasses the construction of civil or industrial facilities representing a residential quarter, the focus is placed on the continuous operation of particular specialized construction departments, subject to the adherence to applicable technologies and compliance with standard deadlines that apply to the construction of buildings. The relevance of this problem stems from the complexity of coordination of works to be performed by contractors and subcontractors, involved in the development of a quarter and responsible to the general contractor. The purpose of this research is to analyze and apply the branch and bound method to the problems arising in the course of scheduling the construction of a quarter using special methods of the scheduling theory.
Materials and methods. The article addresses the problem of continuous operation of special-focus construction departments subject to the adherence to applicable technologies and compliance with standard deadlines set for the construction of individual structures when scheduling the construction of residential quarters.
Results. The solution, based on the branch and bound method, is proposed. The construction of eight buildings, that comprise a residential quarter, is taken as an example. Matrices, representing continuous workflows for different methods of work organization, were obtained; principal parameters of integrated workflows, encompassing the construction of the quarter structures, were calculated with regard for the commencement and completion time for each specialized workflow at each individual structure. A displacement matrix was used to consolidate all eight structures. Two principal methods of reorganizing the integrated quarterly workflow are considered.
Conclusions. The branch and bound method is used to compare original and optimized matrices; calculation results are presented. The strengths and weaknesses of the critical path/continuous resource employment method are illustrated by the project that encompasses the construction of eight facilities in a residential quarter.
Ecofeminismos y variedades de ambientalismos: Estado de la cuestión
Authors: Mediavilla Maria Eugenia , Echavarren José Manuel 
Published: February 2021

Dentro del contexto actual de surgimiento de nuevas formas de activismo ambiental, en el marco de un preocupante escenario de incertidumbre global, este artículo expone las principales teorías desde las que se puede abordar el estudio del ecologismo, sus discursos y sus prácticas, en relación con las diversas manifestaciones de ambientalismos y ecofeminismos. Se encuentra que los ecofeminismos tienen un especial afán narrativo para incorporar la necesidad de los cuidados en las reivindicaciones de los movimientos ambientalistas. Esta propuesta nace en las praxis sociales y territoriales y se va posicionando de manera cada vez más legitimada en investigaciones académicas en el ámbito político y en el debate público internacional. Indagar en las diferentes articulaciones entre ecologismos y feminismos nos permite acercarnos a los usos y apropiaciones de los ecofeminismos, activando nuestra capacidad crítica y de abstracción para imaginar y construir horizontes diferentes, posibles y deseables.
Perlindungan Hukum Kreditor Dalam Warisan Atas Harta Peninggalan Tak Terurus Menurut Sistem Waris Barat
Authors: Rifaldi Setiawan Muhammad , Fakhry Muhammad , Apriano Mahardika 
Published: February 2021

Keberlakuan hukum waris di Indonesia menganut 3 (tiga) sistem Hukum Waris, yaitu; Pertama, Hukum Waris Barat, Kedua,Hukum Waris Adat, Ketiga, Hukum Waris Islam. Sehingga di Indonesia dikenal dengan adanya Pluralisme Hukum Waris. Sistem hukum waris barat mengizinkan bagi ahli waris untuk menolak harta waris yang ditinggalkan oleh pewaris dikarenakan terdapat pasiva yang lebih besar dibandingkan aktiva. maka status dari harta tersebut akan menjadi harta peninggalan tak terurus. Metode Penelitian Hukum Normatif (Doctrinal research), yaitu penelitian yang mengkaji secara sistematis mengenai norma-norma hukum yang mengatur kategori hukum tertentu dan menganalisis hubungan antara norma hukum. Dalam hal ini negara melalui Balai Harta Peninggalan yang akan melakukan pengelolaan terhadap harta tersebut. Sebagi bentuk perlindungan kreditor dapat mengajukan permohonan menjadi ahli waris pengganti untuk pelusanan piutangnya akan dilakukan oleh negara melalui Balai Harta Peninggalan sejumlah dengan nilai utang pewaris atau atau nilai harta atau benda-benda peninggalan pewaris itu mencukupi.
Memorias semióticas y fondos documentales: el caso “Fondo Julio Cortázar”. Una lectura con Lotman
Authors: Gómez Susana 
Published: February 2021

Exploraremos hipótesis epistemológicas abiertas a partir de pensar los fondos documentales de escritor con nociones de Iuri Lotman. ¿Cómo reflexionamos sobre la textualidad en el sistema de un fondo centrado en la obra de un escritor? El sistema cultural, la memoria textual y la crítica sobre obras literarias poseen interesantes facetas que se conocen desde una lectura semiótica
Isabel Lustosa, O jornalista que imaginou o Brasil. Tempo, vida e pensamento de Hipólito da Costa (1774-1823). Campinas, SP, Editora da Unicamp, 2019, 288 páginas
Authors: Pas Hernán 
Published: February 2021

Isabel Lustosa, O jornalista que imaginou o Brasil. Tempo, vida e pensamento de Hipólito da Costa (1774-1823).
Campinas, SP, Editora da Unicamp, 2019, 288 páginas
Comparison of outcomes for single-session and delayed full-thickness applications of meshed skin grafts used to close skin defects after excision of tumors on the distal aspects of the limbs in dogs
Authors: Bonaventura Nicole C. , Ganjei Justin B. 
Published: February 2021

Abstract

OBJECTIVE
To compare outcomes after application of full-thickness, meshed free-skin grafts in single-session versus delayed (staged) procedures after tumor excision from the distal aspects of the limbs in dogs.

ANIMALS
52 client-owned dogs.

PROCEDURES
Medical records were retrospectively reviewed to identify dogs that received full-thickness, meshed free-skin grafts after tumor excision from the distal aspects of the limbs between 2013 and 2018. Signalment; diagnostic test results; comorbidities; procedure type (single session or staged); tumor characteristics; donor site, recipient site, and size of grafts; concurrent procedures; surgeon; antimicrobial administration; external coaptation type; number of bandage applications; percentage graft survival; graft outcome; postoperative complications; and time to complete healing were recorded. Graft outcome was deemed successful if there was full-thickness graft viability over ≥ 75% of the original graft area. Variables were compared between dogs grouped by procedure type.

RESULTS
The number of bandage applications was significantly greater for dogs that had staged versus single-session procedures. Twenty-seven of 30 (90%) and 18 of 22 (82%) skin grafts placed in single-session and staged procedures, respectively, were successful. Percentage graft survival, graft outcome, and complication rate did not differ between groups. All complications were minor. Time to complete healing was significantly longer after staged procedures (median, 51 days) than after single-session procedures (29.5 days).

CONCLUSIONS AND CLINICAL RELEVANCE
Results suggested both procedure types are appropriate for skin graft placement. The shorter healing time and fewer bandage changes associated with single-session skin graft placement may be beneficial after tumor excision. Prospective studies are needed to confirm these findings.