bluuebunny/crossref_metadata_2025_split huggingface dataset:
Motor excitability in bilateral moyamoya vasculopathy and the impact of revascularization
Authors: Acker Gueliz , Giampiccolo Davide , Rubarth Kerstin , Mertens Robert , Zdunczyk Anna , Hardt Juliane , Jussen Daniel , Schneider Heike , Rosenstock Tizian , Mueller Vera , Picht Thomas , Vajkoczy Peter 
Published: September 2021

OBJECTIVE
Motor cortical dysfunction has been shown to be reversible in patients with unilateral atherosclerotic disease after cerebral revascularization. Moyamoya vasculopathy (MMV) is a rare bilateral stenoocclusive cerebrovascular disease. The aim of this study was to analyze the corticospinal excitability and the role of bypass surgery in restoring cortical motor function in patients by using navigated transcranial magnetic stimulation (nTMS).

METHODS
Patients with bilateral MMV who met the criteria for cerebral revascularization were prospectively included. Corticospinal excitability, cortical representation area, and intracortical inhibition and facilitation were assessed by nTMS for a small hand muscle (first dorsal interosseous) before and after revascularization. The clinically and/or hemodynamically more severely affected hemisphere was operated first as the leading hemisphere. Intra- and interhemispheric differences were analyzed before and after direct or combined revascularization.

RESULTS
A total of 30 patients with bilateral MMV were examined by nTMS prior to and after revascularization surgery. The corticospinal excitability was higher in the leading hemisphere compared with the non-leading hemisphere prior to revascularization. This hyperexcitability was normalized after revascularization as demonstrated in the resting motor threshold ratio of the hemispheres (preoperative median 0.97 [IQR 0.89–1.08], postoperative median 1.02 [IQR 0.94–1.22]; relative effect = 0.61, p = 0.03). In paired-pulse paradigms, a tendency for a weaker inhibition of the leading hemisphere was observed compared with the non-leading hemisphere. Importantly, the paired paradigm also demonstrated approximation of excitability patterns between the two hemispheres after surgery.

CONCLUSIONS
The study results suggested that, in the case of a bilateral chronic ischemia, a compensation mechanism between both hemispheres seemed to exist that normalized after revascularization surgery. A potential role of nTMS in predicting the efficacy of revascularization must be further assessed.
Pediatric moyamoya MRI score: an imaging-based scale to predict outcomes in surgically treated pediatric patients with moyamoya
Authors: Garcia Joseph H. , Morshed Ramin A. , Winkler Ethan A. , Li Yi , Fox Christine K. , Fullerton Heather J. , Rutledge Caleb , Beniwal Angad S. , Lawton Michael T. , Abla Adib A. , Gupta Nalin , Hetts Steven W. 
Published: September 2021

OBJECTIVE
Moyamoya is a progressive arteriopathy that predisposes patients to stroke due to stenosis of the intracranial internal carotid arteries and their proximal branches. Despite the morbidity caused by this condition, the ability to accurately predict prognosis for individual patients remains challenging. The goal of this study was to develop a systematic scoring method based on parenchymal findings on preoperative brain MRI to predict long-term outcomes for surgically treated pediatric patients with moyamoya.

METHODS
A retrospective surgical cohort of pediatric patients (≤ 18 years of age at the time of the initial surgery) with moyamoya from a single center were studied. Radiological variables with existing correlations between outcomes in moyamoya or other vascular diseases were chosen to score preoperative MRI based on easily defined parenchymal findings that could be rapidly assessed and used to make a numeric score. Calculated scores were correlated with clinical outcome measures using the Pearson correlation coefficient and area under the receiver operating characteristic curve (AUROC).

RESULTS
A total of 35 children with moyamoya disease or moyamoya syndrome were included in the study, with a median follow-up time of 2.6 years from the time of surgery. The pediatric moyamoya MRI score (PMMS) consists of ischemic changes (0–2; 0 = none, 1 = focal, 2 = diffuse), encephalomalacia (0–2; 0 = none, 1 = focal, 2 = diffuse), and hemorrhage (0–1; 0 = not present, 1 = present). PMMSs were highly correlated with pediatric modified Rankin Scale scores at the last follow-up (r = 0.7, 95% CI 0.44–0.84; p < 0.001) as a six-point scale, and when dichotomized (AUROC = 0.85).

CONCLUSIONS
The PMMS was found to be a simple tool based on preoperative MRI data that could be quickly and easily calculated and correlated with disability. This scoring method may aid future development of predictive models of outcomes for children with moyamoya disease and moyamoya syndrome.
Parthenium hysterophorus, an emergent weedy plant species expands its geographical ranges in Pakistan
Authors: Ali Muhammad , Afridi Riaz Ahmad , Ali Sadiq , Shuja Malik Nawaz , Riaz Hasan 
Published: September 2021

Parthenium hysterophorus [commonly known as Carrot grass; native to American tropics; family Asteraceae] is a flowering, short-lived perennial or an annual invasive-weedy plant. In the recent few years, the plant is spread (in epidemic proportions) vigorously, at least, in the two provinces (KP and Punjab) and the twin capital cities (Islamabad and Rawalpindi). The weed came in the lame light soon after the monsoon rains and floods of September 2012 and August 2013 that hit larger areas of KP and Punjab provinces of Pakistan. The massive boom in the weed was witnessed in areas under floods of the river Kabul and the Indus Ocean. It is speculated that after initial entry into the flood zones, the seeds then germinated and dispersed into the near and farther areas in the country, including hilly areas. The plant is categorized as a poisonous weed, and a source of skin allergies and itching. It may be a cause of increased reports of asthma, cough, fever, and allergies related to eyes in these areas [1, 2]. Due to its vigorous growth and allelopathic effects, the plant soon dominated over all other weeds and crop plants. Furthermore, it has a tremendous potential to withstand abiotic and biotic stresses. Its vigorous growth has resulted in the loss of local floral biodiversity [3]. Specifically in Islamabad, it has dominated completely the wild cannabis (weeds). However, this year, the cannabis weed seems to overcome gradually the parthenium dominance. The coming years may witness the revival of other plant species suppressed by parthenium. Although the plant seems to be resistant/tolerant to biotic stresses, very few plants were identified with leaf rolling, vein yellowing, stunting and bunchy-top like diseases, indicative of begomovirus infection. PCR amplification and sequencing confirmed a symptomatic parthenium plant positive for the viral infection (unpublished observation; Figure 2). Previously, only a single report is available of parthenium being infected with geminiviruses [4].
Currently, no weedicide is available to eradicate the weedy plant. The only available alternative is to drag the plants out of soil along with their roots before they bear seeds. The presence of the plant everywhere on barren lands, streets, along the drains, hilly terraces, orchards, in lawn grass, and in crop fields makes complete eradication almost impossible (Figure 1a-c). Increased ailment linked with parthenium like – toxicity in the livestock and insect pollinators, skin allergies in humans and reduced agricultural productivity necessitates that the government and non-government stakeholders should take stringent measures to save human health, livestock and agricultural production.
Bayeh, Jumana – Oleinikova, Olga (eds.): Democracy, Diaspora, Territory: Europe and Cross-Border Politics
Authors: Anderle Veronika 
Published: September 2021

This volume offers a profoundly new interpretation of the impact of modern diasporas on democracy, challenging the orthodox understanding that ties these two concepts to a bounded form of territory. Considering democracy and diaspora through a deterritorialised lens, it takes the post-Euromaidan Ukraine as a central case study to show how modern diasporas are actively involved in shaping democracy from a distance, and through their political activity are becoming increasingly democratised themselves. An examination of how power-sharing democracies function beyond the territorial state, Democracy, Diaspora, Territory: Europe and Cross-Border Politics compels us to reassess what we mean by democracy and diaspora today, and why we need to focus on the deterritorialised dimensions of these phenomena if we are to adequately address the crises confronting numerous democracies. As such, it will appeal to scholars of sociology and politics with interests in migration and diaspora, political theory, citizenship and democracy.
Dampak Pembangunan Jalur Jalan Lintas Selatan (JJLS) di Yogyakarta Terhadap Perubahan Penggunaan Lahan
Authors: Edy Hendry , Pristyawati Tantin 
Published: September 2021

Di Pulau Jawa, daerah yang pembangunan dan pertumbuhan ekonominya baik pada umumnya berada di sepanjang pantai utara seperti kota Semarang, Pati, Rembang dan Jepara. Sedangkan di bagian selatan pertumbuhan ekonominya cenderung lebih lambat. Sehingga untuk memacu perkembangan wilayah selatan, pemerintah meningkatkan tersedianya infrastruktur berupa Jalur Jalan Lintas Selatan (JJLS). Oleh karena itu dilskuksn penelitian yng bertujuan untuk menganalisis perubahan tata guna lahan yang terjadi di Desa Jetis, dengan adanya pembangunan JJLS. Metode dalam penelitian ini merupakan metode kualitatif, dimana data awal penelitian ini diambil dengan menggunakan observasi langsung di lapangan dan juga wawancara dengan aparat desa dan masyarakat sekitar. Dengan model Miles and Huberman. Analisis dilakukan pada saat pengumpulan data berlangsung dan setelah selesai pengumpulan data pada periode waktu tertentu sampai diperoleh data yang kredibel dan sesuai dengan data yang dibutuhkan. Uji keabsahan data pada penelitian kualitatif meliputi uji, credibility (validitas internal), transferability (validitas eksternal), dependability (reliabilitas) , dan confirmability (obyektivitas). Hasil penelitian yang dilakukan melalui pendekatan analisis peta digital (sistem informasi geografis) dengan cara tumpang susun peta penggunaan lahan hasil interpretasi citra sebelum dan sesudah pembangunan JJLS, diperoleh bahwa belukar/ semak sebesar 1.68 %, sawah tadah hujan 1 % dan tegalan mengalami pengurangan hampir 10,16%. Sedangkan penambahan terjadi pada lahan pemukiman kurang lebih 13%. Pola perubahan penggunaan lahan yang terjadi adalah pola tersebar. Perubahan penggunaan lahan yang terjadi dari lahan belukar, sawah tadah hujan dan tegalan menjadi pemukiman.
Dietary Habits and Physical Activity Affect Random Blood Sugar Levels In Outpatients
Authors: Setianto Budhi , Effendi Effendi , Adriansyah Agus Aan , Asih Akas Yekti Pulih , Bistara Difran Nobel 
Published: September 2021

Background: Diabetes is caused by several etiology resulting in the body not using glucose into the cells, so glucose accumulates in the blood. The pancreas cannot produce the particular hormone in type 1 diabetes. Meanwhile, type 2 diabetes is caused by the inefficient use or deficiency of certain hormones relative to blood glucose levels.
Purpose: This study analyzes the correlation between dietary regulation and physical activity and blood sugar levels in outpatients
Methods: This paper was a cross-sectional analytic study. The population was all outpatients who checked their blood sugar levels at the Internal Medicine Specialist Clinic of Islamic Hospital Surabaya from January to February 2021. Meanwhile, there were 115 respondents with total random sampling. The independent variable was random blood sugar (RBS) levels, while the dependent variables were dietary habits and physical activity. Data collection used medical records at the Internal Medicine Specialist Clinic of Islamic Hospital Surabaya. Then, data analysis utilized Fisher's Exact Test with a significance of 0.05
Results: Most respondents had regular dietary habits (53%) and normal random blood sugar levels (54%). In addition, they had regular physical activity (80%), with frequency once a week (34.8%), and most types of physical activity were gymnastics (34.8%). The Fisher's Exact Test obtained p=0.000 in analyzing between dietary habits and RBG levels. In addition, p=0.000 in evaluating between physical activity and RBG levels.
Conclusion: Dietary habits and physical exercise affect random blood sugar levels in outpatients. Further study should evaluate other factors associated with blood sugar levels.
Suplementasi Kalsium dengan Dark Chocolate dan Susu terhadap Dismenore Pada Remaja Putri
Authors: Aprilianti Cia 
Published: September 2021

Salah satu upaya mencegah serta mengurangi dismenore yaitu dengan menggunakan metode nonfarmakologi, seperti mengkonsumsi zat gizi yang mengandung kalsium, magnesium serta vitamin A, E, B6, dan C yang dapat ditemukan dalam coklat dan susu. Tujuan penelitian ini untuk mengetahui efektifitas suplementasi kalsium terhadap dismenore pada remaja putri. Metode penelitian kuantitatif dengan pendekatan quasy eksperimen dan rancangan penelitian menggunakan non-equivalent control group. Teknik pengambilan sampel menggunakan purposive sampling dan menggunakan rumus uji beda rata-rata (paired) dengan total sampel 50 remaja putri yang mengalami dismenore yang dikelompokkan menjadi dua kelompok. Kelompok dark chocolate sebanyak 25 remaja putri dan kelompok susu sebanyak 25 remaja putri. Analisis data bivariat yang digunakan adalah uji non parametrik yaitu Uji Wilcoxon untuk mengetahui pengaruh sebelum dan sesudah intervensi dan menggunakan dan Uji Mann Whitney untuk mengetahui efektifitas pemberian dark chocolate dan susu terhadap dismenore. Hasil penelitian menunjukan ada pengaruh sebelum dan sesudah pemberian susu terhadap dismenore. Nilai Pv=0,000 sebelum dan sesudah pemberian dark chocolate dan nilai Pv=0,003 sebelum dan sesudah pemberian susu. Dark chocolate lebih efektif dibandingkan dengan susu dalam terhadap dismenore (Pv=0,021).
Pelatihan Blended Learning pada Guru SMA Katolik 1 Kabanjahe
Authors: Pinem Sanjaya , Hutagaol Viktor Edison 
Published: September 2021

Abstract: Technology information using the internet can benefit educators and provide information to students to transfer knowledge has a very high potential. The purposes of these community service are: (1) to expand the insight, knowledge, and experience directly about the model of blended learning for teachers, especially teachers of Sma Katolik 1 Kabanjahe; (2) Teachers can use elearning moodle learning technology. The techniques that are planned to shape the motivation and participation of educators ranging from the benefits of blended learning, and the application of blended learning so that educators in directly implementing it in the classroom. The implementation method starts in a structured manner starting from the initial discussion about blended learning, taking the results of the initial questionnaire, then giving independent tasks to the teachers. This community service was attended by 12 teachers at SMA Katolik 1 Kabanjahe, Kab. Karo. North Sumatra. The important conclusion of this community service is the awareness and ability of educators in using information technology, especially blended learning can increase motivation to educators to provide maximum learning to learners. Keywords: blended learning; moodle; teaching technologyAbstrak: Teknologi informasi dengan menggunakan internet dapat menguntungkan para pendidik dalam memberikan informasi kepada peserta didik. Pengetahuan tentang teknologi informasi mempunyai potensi yang sangat tinggi. Tujuan dari penulisan: (1) memperluas wawasan, pengetahuan dan pengalaman secara langsung tentang model pembelajaran blended learning untuk guru guru khususnya Guru SMA Katolik 1 Kabanjahe; (2) Guru–guru dapat menggunakan teknologi pembelajaran elearning moodle. Teknik yang direncanakan untuk membentuk motivasi dan partisipasi tenaga pendidik mulai dari keuntungan blended learning, dan pengaplikasian blended learning sehingga tenaga pendidik dalam langsung mengimplementasikannya di dalam kelas. Metode pelaksanaan dimulai secara terstruktur mulai dari diskusi awal tentang blended learning, mengambil hasil kuesioner awal, selanjutnya memberikan tugas mandiri kepada guru–guru. Pelaksanaan pengabdian kepada masyarakat ini diikuti oleh 12 guru di SMA Katolik 1 Kabanjahe, kab. Karo. Sumatera Utara. Kesimpulan penting dari pengabdian ini adalah adanya kesadaran dan kemampuan pendidik dalam menggunakan teknologi informasi khususnya blended learning dapat meningkatkan motivasi kepada tenaga pendidik untuk memberikan pembelajaran yang maksimal kepada peserta didik.Kata kunci: blended learning; moodle; teknologi pembelajaran
Pemberdayaan Masyarakat Terkait Pengaruh Obat Herbal dan Upaya Meningkatkan Manajemen Hipertensi
Authors: Fidian Athia , Safitri Yunita , S Avinda Yunita , Munawar Munawar , H Ravi Lukman 
Published: September 2021

Abstract: Hypertension is a chronic disease and the number one killer in the world. Hypertension can attack almost all groups of people around the world, where the number of people who experience hypertension is increasing from year to year. Efforts can be made to reduce the incidence, such as taking blood pressure measurements or health checks, counseling about hypertension and treatment or handling to lower blood pressure. The village of Danurejo, especially in the hamlet of Japunan, is ranked fourth and fourth for people with hypertension. Lack of knowledge about hypertension management is one of the causes. This activity aims to increase public knowledge about hypertension and control the increase in blood pressure with herbal plants that are proven to reduce blood pressure, namely cucumber and celery. The results of the analysis with a comparison table, the results obtained that there are changes between before and before the administration of herbal medicines and health education. The average before the measurement of blood pressure is smaller than before the intervention, thus showing the influence of the administration of herbal medicine and health education. The implications of giving herbal medicines and health education can be used to increase the knowledge of citizens regarding hypertension management, so as to improve the quality of life of the elderly.Keywords: hypertension; hypertension management; herbal drug therapy Abstrak: Penyakit hipertensi merupakan penyakit bersifat menetap dan pembunuh nomor satu di dunia. Hipertensi dapat menyerang hampir semua golongan masyarakat diseluruh dunia, dimana jumlah masyarakat yang mengalami hipertensi semakin bertambah dari tahun ke tahun. Upaya yang dapat dilakukan untuk menurunkan angka kejadian hipertensi diantaranya melakukan kegiatan pengukuran tekanan darah atau pemeriksaan kesehatan, penyuluhan mengenai penyakit hipertensi dan pengobatan atau penanganan untuk menurunkan tekanan darah. Desa Danurejo terutama di dusun Japunan menjadi peringkat keempat untuk penderita hipertensi. Rendahnya pengetahuan tentang manajemen hipertensi menjadi salah satu penyebabnya. Kegiatan ini bertujuan untuk meningkatkan pengetahuan masyarakat tentang penyakit hipertensi dan mengontrol peningkatan tekanan darah dengan tanaman herbal yang sudah terbukti dapat menurunkan tekanan darah yaitu mentimun dan seledri. Hasil analisis dengan tabel perbandingan, didapatkan hasil bahwa terdapat perubahan antara sebelum dan sesudah pada pemberian obat herbal dan pendidikan kesehatan. Rata-rata sesudah pengukuran tekanan darah lebih kecil dari sebelum intervensi, sehingga menunjukan adanya pengaruh dari pemberian obat herbal dan pendidikan kesehatan. Implikasi pemberian obat herbal dan pendidikan kesehatan dapat di terapkan untuk meningakatkan pengetahuan warga terkait manajemen hipertensi, sehingga dapat meningkatkan kualitas hidup lansia.Kata kunci: hipertensi; manajemen hipertensi; terapi obat herbal
Hallazgos moleculares y citogenéticos en pacientes pediátricos, diagnosticados de leucemia linfoide aguda
Authors: González Cabrera Andrés , Alvarado Soto Diana , Cisneros López Migleth , Ramírez Pico Juan , Poveda Ayora María , Espín Custodio Luis 
Published: September 2021

Introducción: La leucemia linfoblástica aguda (LLA) es la neoplasia maligna de mayor frecuencia en la infancia; advertir sus alteraciones moleculares y citogenéticas permite establecer el riesgo, el pronóstico asociado y además plantear esquemas terapéuticos apropiados; el objetivo de este estudio es conocer la prevalencia de estas alteraciones en nuestra población.
Metodología: Estudio de tipo retrospectivo y transversal, basado en los registros de las alteraciones moleculares y citogenéticas de los pacientes pediátricos diagnosticados con leucemia linfoblástica aguda durante el periodo comprendido entre enero 2014 a diciembre de 2018, en el Hospital del Instituto Oncológico Nacional “Dr. Juan Tanca Marengo”.
Resultados: Se incluyeron 338 pacientes, de los cuales el principal grupo etario lo constituyo el de 0 a 4 años; el inmunofenotipo más observado fue el B-común. En el 24.56% de los casos se detectó altercaciones estructurales, principalmente por estudios de biología molecular; siendo la más común la translocación t(12;21). Se obtuvieron resultados por citogenética en 167 pacientes, en cuales la principal alteración numérica correspondió a la hiperdiploidía de entre 47 a 51 cromosomas.
Conclusión: Los avances en la caracterización molecular y citogenética de la LLA, permiten mejorar la estratificación de su riesgo; y establecer estrategias terapéuticas que permitan una mejoría en la sobrevida.
PELATIHAN MERANCANG UJIAN ONLINE MENGGUNAKAN GOOGLE FORM UNTUK GURU-GURU DI WILAYAH KECAMATAN PAMPANGAN KABUPATEN OGAN KOMERING ILIR
Authors: Yunani Alhadi Novi Rustiana Dewi , Susanti Eka , Cahyawati Dian , Suprihatin Bambang , Hanum Herlina 
Published: September 2021

During the pandemic, teaching and learning activities in Indonesia were carried out online. Apart from online learning activities, the learning evaluation process is also carried out online. Computer applications can be used as a tool to carry out learning evaluation activities. In this service, training is given to make online exams using google form. The training participants were 32 teachers with undergraduate educational backgrounds consist of elementary, junior high school, senior high school public and private school teachers in Pampangan Subdistrict, Ogan Komering district, South Sumatra. The training activities are carried out for one day. The activity stages consist of the preparation, implementation and evaluation stages. Based on the results at the implementation and evaluation stages, it can be concluded that participants in online exam preparation training activities can make online exams using google form.
Selama masa pandemi kegiatan belajar mengajar di Indonesia dilakukan secara online atau dalam jaringan. Selain kegiatan pembelajaran online, proses evaluasi pembelajaran juga dilakukan secara online. Aplikasi komputer dapat digunakan sebagai alat bantu untuk melaksanakan kegiatan evaluasi pembelajaran. Dalam kegiatan pengabdian ini diberikan pelatihan membuat ujian online dengan menggunakan google form. Peserta pelatihan sebanyak 32 orang guru dengan latar belakang pendidikan sarjana yang terdiri dari guru sekolah dasar, sekolah menengah pertama dan sekolah menengah atas negeri dan swasta di Kecamatan Pampangan, Kabupaten Ogan Komering Ilir, Sumatera Selatan. Kegiatan pelatihan dilaksanakan selama satu hari. Tahapan kegiatan terdiri dari tahap persiapan, pelaksanaan dan evaluasi. Berdasarkan hasil pada tahap pelaksanaan dan evaluasi dapat disimpulkan bahwa peserta kegiatan pelatihan penyusunan ujian online dapat membuat ujian online menggunakan google form.