bluuebunny/crossref_metadata_2025_split huggingface dataset:
Meningkatkan hasil belajar peserta didik dengan menggunakan E-modul berbasis 3D pageflip professional dengan model discovery learning (A useful learning E-modul based 3D pageflip professional with use discovery learning model)
Authors: Asmarani Nadhiifa Eka , Arief Mohammad , Churiyah Madziatul 
Published: August 2021

Abstrak
Pandemi covid-19 yang sedang melanda berbagai negara termasuk Indonesia telah mempengaruhi berbagai aspek kehidupan salah satunya yaitu pendidikan, dampak dari adanya covid-19, saat ini pembelajaran dilakukan secara daring (online) dan tatap muka secara bergiliran. Sehingga guru dituntut untuk kreatif mengoptimalkan teknologi dalam kegiatan pembelajaran. Oleh karena itu, penelitian ini bertujuan untuk menghasilkan E-modul berbasis 3D PageFlip Professional dengan Model Discovery Learning pada Mata Pelajaran Administrasi Umum untuk meningkatkan hasil belajar peserta didik. Produk e-modul ini berisi pembahasan materi dan soal-soal serta dilengkapi menu Mari Mengamati hingga Mari Menyimpulkan. E-modul ini bisa diakses offline melalui Personal Computer/Laptop dengan Aplikasi 3D PageFlip Professional atau secara online melalui HP Android. Penelitian dan pengembangan ini menggunakan model Research and Development Borg and Gall yang telah dimodifikasi. Teknik analisis data yang digunakan adalah deskriptif persentase dan uji independent sample t-test. Hasil penelitian dan pengembangan ini adalah E-modul berbasis 3D PageFlip Professional dengan Model Discovery Learning pada Mata Pelajaran Administrasi Umum Kompetensi Dasar Bentuk Struktur Organisasi dan Fungsi Manajemen yang telah dinyatakan sangat valid dan layak digunakan dalam pembelajaran kearsipan oleh ahli media, ahli materi, dan 6 peserta didik uji coba kelompok kecil serta terbukti dapat meningkatkan hasil belajar secara signifikan pada uji coba kelompok besar. Sehingga dapat disimpulkan bahwa E-Modul Administrasi Umum layak dan efektif digunakan sebagai bahan pembelajaran untuk meningkatkan hasil belajar peserta didik pada mata pelajaran administrasi umum.
ANALISA HEAD LOSSES DENGAN PENERAPAN SIMULASI PADA DIAMETER PIPA DAN PENGARUH NILAI NET POSITIVE SUCTION HEAD TERHADAP TERBENTUKNYA KAVITASI PADA POMPA
Authors: Aisyah Siti , Effendi Zulham , Yoga Pratama Wahyu 
Published: August 2021

Pompa bekerja dengan mengkonversi energi mekanik menjadi energi kinetic dimana sepanjang aliran fluida akan mengalami kerugian aliran yang menyebabkan penurunan tekanan dorong di sisi discharge pompa. Hal ini disebabkan karena gesekan fluida dengan dinding pipa, dan penggunaan elbow, valve, dan lain-lain. Analisa ini bertujuan untuk menghitung besarnya kerugian tekanan (head losses) pada luas penampang pipa, Nett Positive Suction Head yang tersedia (NPSHa), dan pada akhirnya akan dibandingkan dengan Nett Positive Suction Head yang diperlukan (NPSHr) dari pompa. Hasil penelitian diperoleh kecepatan aliran pada pipa hisap dan tekan adalah 0,8567 , bilangan Reynold untuk pipa 4” adalah 295050 m (aliran turbulen), relative pipe Roughness untuk pipa 4” adalah 0,0015, kerugian pada pipa hisap sebesar 0,1082 m, kerugian pada pipa tekan 0,0927 m, kerugian head pada sambungan pipa elbow 900 sebesar 0,0012 m Kerugian head pada hambatan gate valve sebesar 0,0059 m.
Study of Water Requirements and Coefficient of Rice Crops (Oryza sativa L) in the Lebak Swamp : Kajian Kebutuhan Air dan Koefisien Tanaman Padi (Oryza sativa L) di Lahan Rawa Lebak
Authors: Triana Arjuna Neni , Purnomo Rahmad Hari , Khalid Feldy 
Published: August 2021

ABSTRACTThe purpose of this research is to find out water requirements and coefficient of rice plant in lebak swamp land. The research method used in this study is an experimental method with descriptive data presentation in the form of tables and graphs. The parameters observed included the net water requirements of rice for rice, the evapotranspiration value of plants, the value of crop coefficients and the value of percolation. The results showed that the net water requirements of rice fields were 3.26 mm / day, 6.15 mm / day and 11.48 mm / day. The actual evABSTRAKTujuan penelitian untuk mengetahui kebutuhan air dan koefisen tanaman padi di lahan rawa lebak. Metode penelitian yang digunakan pada penelitian ini adalah metode eksperimental dengan penyajian data secara deskriptif dalam bentuk tabel dan grafik. Parameter yang diamati meliputi kebutuhan air neto sawah untuk padi, nilai evapotranspirasi tanaman, nilai koefisien tanaman dan nilai perkolasi. Hasil penelitian menunjukkan bahwa kebutuhan air neto sawah berturut-turut adalah 3,26 mm/hari, 6,15 mm/hari dan 11,48 mm/hari. Nilai evapotranspirasi aktual (ETc) dari fase pertumbuhan awal, fase vegetatif aktif, fase pembuahan, dan fase pematangan biji berturut-turut adalah 1,23 mm/hari, 2,57 mm/hari, 2,64 mm/hari dan 1,57 mm/hari, sedangkan untuk koefisien tanaman berturut-turut adalah 0,42; 0,89; 1,003 dan 0,62. Nilai evapotranpirasi dan koefisien tanaman terbesar terdapat pada umur pertumbuhan 31 sampai 65 hari atau fase pembuahan. Nilai perkolasi untuk setiap tahap pertumbuhan adalah 0,27 cm/hari, 3,24 cm/hari, 4,23 cm/hari dan 10,63 cm/hari.
Evaluation de la contribution de l’irrigation à la croissance économique et agricole : cas du Maroc
Authors: Mengoub Fatima Ezzahra , Lejars Caroline , Doukkali Mohammed Rachid 
Published: August 2021

Situé dans une zone géographique où les ressources hydriques sont limitées, le Maroc a multiplié les efforts pour gérer ses ressources en eau. Ces efforts se sont concrétisés à travers l’amélioration continue du cadre législatif régissant le secteur de l’eau et s’adaptant aux nouvelles contraintes qu’elles soient climatiques, technologiques et/ou économiques. Dans ce sens, ce travail vise l’évaluation de l’impact de ces interventions publiques sur la croissance agricole et économique observées. La démarche méthodologique adoptée se base sur la méthode de comptabilité de croissance ou « Growth Accounting », développée par Solow en 1957. Elle permet de décomposer la croissance en contribution des facteurs et celle de la productivité. Les résultats de cette étude confirment le rôle primordial que joue l’agriculture en tant que moteur de croissance de l’économie marocaine. Ils montrent également que la contribution de l’eau à la croissance de la valeur ajoutée agricole est de l’ordre de 2% et qu’elle demeure tributaire des conditions climatiques, qui à leur tour changent sous l’effet du réchauffement climatique.
Located in a geographical area with limited water resources, Morocco has multiplied its efforts to manage its water resources. These efforts have been materialized through the continuous improvement of the legislative framework governing the water sector and adapting to the new constraints whether they are climatic, technological and/or economic. In this sense, this work aims at evaluating the impact of these public interventions on the observed agricultural and economic growth. The methodological approach adopted is based on the growth accounting method developed by Solow in 1957. It allows for the decomposition of growth into factor contributions and productivity contributions. The results of this study confirm the primary role played by agriculture as an engine of growth in the Moroccan economy. They also show that the contribution of water to the growth of agricultural value added is around 2% and that it remains dependent on climatic conditions which are changing under global warming.
An Interview with Nobel Laureate David Baltimore, PhD
Authors: Lederman Michael M. , Greenspan Neil 
Published: August 2021

In an online interview, Nobel Laureate David Baltimore, Ph.D., reflected on his contributions to biomedical science that have had a major influence on the fields of molecular biology, virology, cancer, and immunology. Dr. Baltimore is President Emeritus and Distinguished Professor of Biology at the California Institute of Technology. Among other notable works, he discovered the critical nuclear transcription factor NF Kappa B and the Rag1 and Rag2 proteins that rearrange adaptive immune cell receptors.
His career path, he says, evolved naturally, as math and science came easily to him. As a high school student, he participated in a summer program at the Jackson Lab in Bar Harbor, Maine, where he says he came away feeling that experimental biology was exciting and rewarding.
“That's where I discovered that the frontiers of science, were not so distant; that I could actually make a discovery that nobody else in the world knew about,” he says.
And that he did. Independently, he and Howard Temin discovered the viral enzyme reverse transcriptase revising the canon of cellular information transfer. They published back-to-back papers in Nature demonstrating that this enzyme in virus particles could transcribe RNA to DNA. Both received a Nobel Prize for this work.
In reflecting on his early experience evaluating how to work with recombinant DNA and how we should scientifically and safely approach gain of function research, he says, “We have to be very honest with ourselves about what might hold danger, and we have to control our instinct … to do anything we can to generate progress and understanding of life. …At the same time, we don’t want to hold back progress, and so there is a balancing.”
Dr. Baltimore also discussed his optimism about vectored immunoprophylaxis as a strategy for prevention of HIV and his doubt that scalable strategies will be able to cure HIV. He also reflected on his philosophy for the training of young scientists and the successful training program that he developed at the Whitehead Institute.
An Effort to Increase the Independence of Pregnant Women in Detecting High Risk and Complications of Pregnancy
Authors: Mardiyanti Ika , Anggasari Yasi 
Published: August 2021

Health problems for pregnant women, both physically and psychologically, have an impact on the quality of life of the mother and the baby she is carrying. Women with high-risk pregnancies need to prepare themselves with more attention to their health conditions in facing pregnancy. Several factors that influence the independence of pregnant women in early detection of high risk pregnancies include age, developmental conditions, health conditions, cultural orientation, health care systems, family system factors or family support, lifestyle, environmental factors and available resources. The output target to be achieved in the implementation of this community service activity is to increase the understanding and skills of pregnant women about high-risk pregnancies and to be published in national journals. Efforts to increase the independence of pregnant women in detecting high risks and complications of pregnancy through the use of the health of both mother and childbook, Skor Pudji Rochyati and birth planning and complication prevention program stickers are a form of self-awareness for pregnant women and supported by social support by their families, it is hoped that pregnant women will be fully aware of the signs and dangers that occur. on himself and checked himself into a health facility and wanted to be referred to a higher level of service precisely and quickly.
Noni Fermentation as an Effort to Prevent COVID 19 in Sidoarjo, Indonesia
Authors: Ridhotillah Ainun , Andjariani Endang Wahju , Ettyani Ettyani 
Published: August 2021

Covid 19 epidemic has made people more aware of the importance of health and personal hygiene. They strive to increase body immunity against various viruses, bacteria, and germs. One of the plants capable of improving body immunity is noni plant. It is much likely to prevent corona virus. Noni fruit contains substance capable of preventing cancer and antimicrobials. skopoletin dan anthraquinon of noni fruit has anti-septic substance that can kill bacteria and fungi in the body. Alkaloid of morinda citrifolia is also effective to increase immunity and to lower cholesterol. Due to its anti-virus property, noni can also cure fever, pain, and cough. For noni fermented beverage, the analysis of SWOT (Strength, Weakness, Opportunities, Threats) has been made for its potential market. The fermented noni drink is expected to be an alternative herbal drink which is healthy and economic-valued. This product is also expected to inspire an innovative enterpreneurship. By making use of often-discarded-noni fruit into fermented noni beverage, people can employ others as noni fruit collectors, thus employment created. The manufacture of the product includes pre-production stage, fermentation production, packaging, promoting, launching, and to the post-production stage. The fermented noni has its particular blend of fresh and sweet flavors. Consumers may get attracted to buy this rich-nutrient herbal drink. The manufacture of fermented noni drink can empower the people of desa pagerngumbuk. They can start by planting the noni plant. Hence, it is expected to make a new enterpreneuship activity among the society of desa Pagerngumbuk. This can be initiated particularly by the women of PKK.
Low Effective Material Loss TOPAS Based Single-Mode Photonic Crystal Fiber with High Core Power Fraction in the THz Waveguiding
Authors: Hossain Selim , Sen Shuvo 
Published: August 2021

Abstract
In this study, five layers of hexagonal cladding and two elliptical air holes based on photonic crystal fiber are discussed highly for many communication areas by decreasing different types of losses such as effective material loss (EML), scattering loss, and conﬁnement loss in the terahertz (THz) waveguiding. Our suggested fiber (H-PCF) and all simulation results are obtained with the finite element method (FEM) and the perfectly matched layer (PML) boundary conditions based COMSOL Multiphysics software have been used to design in the THz region. After investigating all the graphical results, this optical communication-related H-PCF fiber discloses an extremely low effective material loss (EML) of 0.0184 cm−1, with an effective area of 7.07×10-8 m2 and flow of power in the core region of 88% at 1 terahertz (THz). Here, other simulation parameters such as conﬁnement loss, scattering loss, and V-parameter are also presented with a proper graph. So, we can easily say that the reported H-PCF fiber is strongly appropriate for different types of short and long-distance communication applications in the terahertz (THz) wave pulse region.
The Perceived Impact of the Covid-19 Pandemic on Medical Student Education and Training – An International Survey
Authors: Wanigasooriya Kasun , Beedham William , Laloo Ryan , Karri Rama Santhosh , Darr Adnan , Layton Georgia R. , Logan Peter , Tan Yanyu , Mittapalli Devender , Patel Tapan , Mishra Vivaswan Dutt , Odeh Osama Faleh , Prakash Swathi , Elnoamany Salma , Peddinti Sri Ramya , Daketsey Elorm Adzoa , Gadgil Shardool , Bouhuwaish Ahmad , Ozair Ahmad , Bansal Sanchit , Elhadi Muhammed , Godbole Aditya Amit , Axiaq Ariana , Rauf Faateh Ahmad , Ashpak Ashna , Collaborative TMS 
Published: August 2021

Abstract
Background:The Covid-19 pandemic led to significant changes and disruptions to medical education worldwide. We evaluated medical student perceived views on training, their experiences and changes to teaching methods during the pandemic.MethodsAn online survey of medical students was conducted in the Autumn of 2020. An international network of collaborators facilitated participant recruitment. Students were surveyed on their perceived overall impact of Covid-19 on their training and several exposure variables. Univariate analyses and adjusted multivariable analysis were performed to determine strengths in associations.ResultsA total of 1604 eligible participants from 45 countries took part in this survey and 56.3% (n=860) of these were female. The median age was 21 (Inter Quartile Range:21-23). Nearly half (49.6%, n=796) of medical students were in their clinical years. The majority (n=1356, 84.5%) were residents of a low or middle income country. A total of 1305 (81.4%) participants reported that the Covid-19 pandemic had an overall negative impact on their training. On adjusted analysis, being 21 or younger, females, those reporting a decline in conventional lectures and ward based teaching were more likely to report an overall negative impact on their training (p≤0.001). However, an increase in clinical responsibilities was associated with lower odds of participants reporting a negative impact on training (p<0.001). The participant’s resident nation economy and stage of training were associated with some of the participant training experiences surveyed (p<0.05). ConclusionMedical students reported an overall significant negative impact of the Covid-19 pandemic on their undergraduate training. The efficacy of novel virtual methods of teaching to supplement traditional teaching methods warrants further research.
Cytoreductive Surgery (CRS) Plus Hyperthermic Intraperitoneal Chemotherapy (HIPEC) vs CRS Alone for Treatment of Endometrial Cancer with Peritoneal Metastases: A Multi-Institutional Study from PSOGI and BIG RENAPE Groups
Authors: DAVID Manuel GOMES , Bakrin N. , Salleron J. , Kaminsky M. C. , Bereder J. M. , Tuech J. J. , Lehmann K. , Mehta S. , Glehen O , Marchal F. 
Published: August 2021

Abstract
ObjectiveTo investigate the benefit of cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) for the treatment of endometrial peritoneal carcinomatosis compared to CRS alone.MethodsWe conducted a retrospective multicentre study of patients from experienced centres in treating peritoneal malignancies from 2002 to 2015. Patients who underwent surgery for peritoneal evolution of endometrial cancer (EC) where included. Two groups of 30 women were matched and compared: “CRS +HIPEC” which used HIPEC after CRS, and “CRS only” which did not used HIPEC. We analysed clinical, pathologic and treatment data for patients with peritoneal metastases from EC. The outcome measures were morbidity, overall survival (OS), and progression-free survival (PFS).ResultsIn “CRS plus HIPEC” group, 96,7% of women were treated for recurrence, while in “CRS only” 83,3 were treated for primary disease. There was no significant difference between Peritoneal Carcinomatosis Index at laparotomy or Completeness of Cytoreduction score. Grade III and IV complications rates did not significantly differ between “CRS plus HIPEC” group and “CRS only” group (20.7% vs 20.7%, p=0.739). Survival analysis showed no statistical difference between both groups. Median OS time was 19.2 months in “CRS plus HIPEC” group and 29.7 months in “CRS only” group (p=0.606). Median PFS survival time was 10.7 months in “CRS plus HIPEC” group and 13.1 months in “CRS only” group (p=0.511).ConclusionThe use of HIPEC combined to CRS appears to be as effective, well tolerated and feasible as CRS alone in patients with primary or recurrent peritoneal metastasis of endometrial cancer.
Prophylactic Effect of Memantine in Docetaxel Induced Neuropathy in Patients With Breast Cancer
Authors: Mohammadzadeh Pegah , Shaseb Elnaz , Sanaat Zohreh , Sarbakhsh Parvin , Gholami Nasrin , Boostani Farnaz , Akbari Farideh , Ghaffary Saba 
Published: August 2021

Abstract
Purpose

Peripheral neuropathy is a complication of taxane that in severe cases can limit the optimal treatment. The aim of this study was to evaluate the efficacy of memantine in prevention of docetaxel induced peripheral neuropathy in patients with breast cancer.
Methods

In this randomized clinical trial, 40 women between the ages of 18 and 64 years with non-metastatic breast cancer (stages I to III) were included (registry number: IRCT20160310026998N9 and registry date: 26 March 2019). All patients were treated with the AC-T regimen (with docetaxel). Patients in intervention group received memantine at a dose of 20 mg for 8 weeks at the beginning of the first cycle of docetaxel. Patients in control group did not take any medication for neuropathy prevention. To assess the neuropathy, DN4 and CTCAE questionnaires were used at baseline, one months, three months and six months after the intervention.
Results

The DN4 questionnaire score was remarkably less in memantine group in follow up one (p-value: 0.033) and three (p < 00.1). The CTCAE follow up score did not change during study. The Neuropathy duration and Neuropathy onset, were shown significant difference between the intervention and control groups, p = 0.050 and p = 0.001, respectively. From 40 patients, 8 (40%) in memantine group and 2 (10%) in control group, did not experience any kind of neuropathy.
Conclusion

Data showed that prophylactic administration of memantine 20 mg/day has been effective in prevention of severity and incidence of docetaxel induced neuropathy in patients with breast cancer.
Associations of FKBP5 Polymorphisms and Methylation and Parenting Style With Depressive Symptoms Among Chinese Adolescents
Authors: Guo Lan , Wang Wanxin , Guo Yangfeng , Du Xueying , Shi Guangduoji , Lu Ciyong 
Published: August 2021

Abstract
Background

Genetic factors may interplay with environmental stressors to contribute to risks of depressive symptoms. This study aimed to investigate the association of FKBP5 polymorphisms and DNA methylation with depressive symptoms among Chinese adolescents, considering the role of parenting style.
Methods

This study used a nested case-control study design based on a cohort study, and the case (n = 120) and control groups (n = 118) were matched with age. Depressive symptoms, parenting style, and other demographics were measured. Fourteen potential polymorphisms and one promoter region in the FKBP5 gene were selected for genotyping and methylation analysis.
Results

In the adjusted models, a significant association between FKBP5 rs7757037 and depressive symptoms was found in the codominant model (AG vs. GG; adjusted odds ratio [AOR] = 2.37, 95% CI = 1.07–5.28) and dominant model (AA + AG vs. GG; AOR = 2.22, 95% CI = 1.05–4.69); rs2817032 polymorphism was associated with depressive symptoms in the codominant model and dominant model. Significant interactions between rs7757037 and the father’s parenting style were found in the codominant model (P = 0.037) and dominant model (P = 0.038), but the gene-environment interactions were not significant after correcting for multiple testing. The main and interactive effects of FKBP5 methylation status on depressive symptoms were not observed, and no significant mediations were found in the association between FKBP5 polymorphisms and depressive symptoms through the methylation mechanism.
Conclusions

Further studies are required to confirm the effect of FKBP5 polymorphisms and methylation as well as their interactions with parenting styles in larger samples.