bluuebunny/crossref_metadata_2025_split huggingface dataset:
Frequency and phenotype of headache in covid-19: a study of 2194 patients
Authors: García-Azorín David , Sierra Álvaro , Trigo Javier , Alberdi Ana , Blanco María , Calcerrada Ismael , Cornejo Ana , Cubero Miguel , Gil Ana , García-Iglesias Cristina , Lozano Ana Guiomar , Martínez Badillo Cristina , Montilla Carol , Mora Marta , Núñez Gabriela , Paniagua Marina , Pérez Carolina , Rojas María , Ruiz Marta , Sierra Leticia , Hurtado María Luisa , Guerrero Peral Ángel Luis 
Published: July 2021

AbstractTo estimate the frequency of headache in patients with confirmed COVID-19 and characterize the phenotype of headache attributed to COVID-19, comparing patients depending on the need of hospitalization and sex, an observational study was done. We systematically screened all eligible patients from a reference population of 261,431 between March 8 (first case) and April 11, 2020. A physician administered a survey assessing demographic and clinical data and the phenotype of the headache. During the study period, 2194 patients out of the population at risk were diagnosed with COVID-19. Headache was described by 514/2194 patients (23.4%, 95% CI 21.7–25.3%), including 383/1614 (23.7%) outpatients and 131/580 (22.6%) inpatients. The headache phenotype was studied in detail in 458 patients (mean age, 51 years; 72% female; prior history of headache, 49%). Headache was the most frequent first symptom of COVID-19. Median headache onset was within 24 h, median duration was 7 days and persisted after 1 month in 13% of patients. Pain was bilateral (80%), predominantly frontal (71%), with pressing quality (75%), of severe intensity. Systemic symptoms were present in 98% of patients. Headache frequency and phenotype was similar in patients with and without need for hospitalization and when comparing male and female patients, being more intense in females.Trial registration: This study was supported by the Institute of Health Carlos III (ISCIII), code 07.04.467804.74011 and Regional Health Administration, Gerencia Regional de Salud, Castilla y Leon (GRS: 2289/A/2020).
Entropy production and mixed convection within trapezoidal cavity having nanofluids and localised solid cylinder
Authors: Ishak Muhamad S. , Alsabery Ammar I. , Hashim Ishak , Chamkha Ali J. 
Published: July 2021

AbstractThe entropy production and mixed convection within a trapezoidal nanofluid-filled cavity having a localised solid cylinder is numerically examined using the finite element technique. The top horizontal surface moving at a uniform velocity is kept at a cold temperature, while the bottom horizontal surface is thermally activated. The remaining surfaces are maintained adiabatic. Water-based nanofluids ($$\text {Al}_2\text {O}_3$$

Al
2

O
3

nanoparticles) are used in this study, and the Boussinesq approximation applies. The influence of the Reynolds number, Richardson number, nanoparticles volume fraction, dimensionless radius and location of the solid cylinder on the streamlines, isotherms and isentropic are examined. The results show that the solid cylinder’s size and location are significant control parameters for optimising the heat transfer and the Bejan number inside the trapezoidal cavity. Furthermore, the maximum average Nusselt numbers are obtained for high R values, where the average Nusselt number is increased by 30% when R is raised from 0 to 0.25.
Accurate prediction of breast cancer survival through coherent voting networks with gene expression profiling
Authors: Pellegrini Marco 
Published: July 2021

AbstractFor a patient affected by breast cancer, after tumor removal, it is necessary to decide which adjuvant therapy is able to prevent tumor relapse and formation of metastases. A prediction of the outcome of adjuvant therapy tailored for the patient is hard, due to the heterogeneous nature of the disease. We devised a methodology for predicting 5-years survival based on the new machine learning paradigm of coherent voting networks, with improved accuracy over state-of-the-art prediction methods. The ’coherent voting communities’ metaphor provides a certificate justifying the survival prediction for an individual patient, thus facilitating its acceptability in practice, in the vein of explainable Artificial Intelligence. The method we propose is quite flexible and applicable to other types of cancer.
Metal organic framework derived NaCoxOy for room temperature hydrogen sulfide removal
Authors: Gupta Nishesh Kumar , Bae Jiyeol , Kim Kwang Soo 
Published: July 2021

AbstractNovel NaCoxOy adsorbents were fabricated by air calcination of (Na,Co)-organic frameworks at 700 °C. The NaCoxOy crystallized as hexagonal microsheets of 100–200 nm thickness with the presence of some polyhedral nanocrystals. The surface area was in the range of 1.15–1.90 m2 g−1. X-ray photoelectron spectroscopy (XPS) analysis confirmed Co2+ and Co3+ sites in MOFs, which were preserved in NaCoxOy. The synthesized adsorbents were studied for room-temperature H2S removal in both dry and moist conditions. NaCoxOy adsorbents were found ~ 80 times better than the MOF precursors. The maximum adsorption capacity of 168.2 mg g−1 was recorded for a 500 ppm H2S concentration flowing at a rate of 0.1 L min−1. The adsorption capacity decreased in the moist condition due to the competitive nature of water molecules for the H2S-binding sites. The PXRD analysis predicted Co3S4, CoSO4, Co3O4, and Co(OH)2 in the H2S-exposed sample. The XPS analysis confirmed the formation of sulfide, sulfur, and sulfate as the products of H2S oxidation at room temperature. The work reported here is the first study on the use of NaCoxOy type materials for H2S remediation.
Analyzing the link between anxiety and eating behavior as a potential pathway to eating-related health outcomes
Authors: Hussenoeder Felix S. , Conrad Ines , Engel Christoph , Zachariae Silke , Zeynalova Samira , Glaesmer Heide , Hinz Andreas , Witte Veronika , Tönjes Anke , Löffler Markus , Stumvoll Michael , Villringer Arno , Riedel-Heller Steffi G. 
Published: July 2021

AbstractAnxiety is a widespread phenomenon that affects various behaviors. We want to analyze in how far anxiety is connected to eating behaviors since this is one potential pathway to understanding eating-related health outcomes like obesity or eating disorders. We used data from the population-based LIFE-Adult-Study (n = 5019) to analyze the connection between anxiety (GAD-7) and the three dimensions of eating behaviors (FEV)—Cognitive Restraint, Disinhibition, and Hunger—while controlling for sociodemographic variables, smoking, physical activity, personality, and social support. Multivariate regression analyses showed significant positive associations between anxiety and Disinhibition as well as Hunger, but not between anxiety and Cognitive Restraint. Interventions that help individuals to better regulate and cope with anxiety, could be one potential pathway to reducing eating disorders and obesity in the population.
Soil texture as a key driver of polycyclic aromatic hydrocarbons (PAHs) distribution in forest topsoils
Authors: Łyszczarz Stanisław , Lasota Jarosław , Szuszkiewicz Maria Magdalena , Błońska Ewa 
Published: July 2021

AbstractDue to the dynamic development of civilization and the increasing demand for energy, pollution by harmful chemicals, including polycyclic aromatic hydrocarbons (PAHs) compounds, is a serious threat to forest soils. The aim of the study was to determine the role of texture in the distribution of polycyclic aromatic hydrocarbons (PAHs) and trace elements in forest soils. The areas with different texture ranging from sand through sandy loam to silt loam were selected for the study. The study was carried out in the Chrzanów Forest District in southern Poland (50° 7′ 18 N; 19° 31′ 29 E), which in one of the most intensive industrial emission zones in Europe. The soil samples for properties determination were collected from locations distributed on a regular grid 100 × 100 m (20 points). The samples were collected from the humus horizon (0–10 cm) after removing organic horizon. Basic chemical properties, heavy metal content, polycyclic aromatic hydrocarbons (PAHs) content and magnetic susceptibility values were determined in soil samples. Additionally, enzymatic activity and microbiological biomass was determined in the samples. Our study confirmed the importance of texture in PAHs distribution. A strong correlation between PAHs content and silt content in the soils studied was noted. The regression tree analysis confirmed the importance of the silt content, followed by soil organic carbon in PAHs distribution. Organic carbon content and nitrogen content played a predominant role in controlling the microbial activity. In our study, we did not note a relationship between enzymatic activity, microbiological soil biomass and the amount of PAHs. This may be due to the effective sorption and immobilization of PAHs by particles of fine fractions, especially silt. Obtained results confirmed the usefulness of magnetic susceptibility in the assessment of heavy metals contamination of forest soils. We noted high correlation between magnetic susceptibility value and heavy metals content. Moreover, the relationship between magnetic susceptibility and soil texture of the topsoil was also observed.
COVID-19 lockdown has altered the dynamics between affective symptoms and social isolation among older adults: results from a longitudinal network analysis
Authors: Yu Junhong , Mahendran Rathi 
Published: July 2021

AbstractThe COVID-19 lockdown has drastically limited social interactions and brought about a climate of fear and uncertainty. These circumstances not only increased affective symptoms and social isolation among community dwelling older adults but also alter the dynamics between them. Using network analyses, we study the changes in these dynamics before and during the lockdown. Community-dwelling older adults (N = 419) completed questionnaires assessing depression, anxiety, and social isolation, before the COVID-19 pandemic, as part of a cohort study, and during the lockdown period. The total scores of these questionnaires were compared across time. For the network analyses, partial correlation networks were constructed using items in the questionnaires as nodes, separately at both timepoints. Changes in edges, as well as nodal and bridge centrality were examined across time. Depression and anxiety symptoms, and social isolation had significantly increased during the lockdown. Significant changes were observed across time on several edges. Greater connectivity between the affective and social isolation nodes at lockdown was observed. Depression symptoms have become more tightly coupled across individuals, and so were the anxiety symptoms. Depression symptoms have also become slightly decoupled from those of anxiety. These changing network dynamics reflect the greater influence of social isolation on affective symptoms across individuals and an increased vulnerability to affective disorders. These findings provide novel perspectives and translational implications on the changing mental health context amidst a COVID-19 pandemic situation.
Cognitive Assessments for Patients With Neurological Conditions: A Preliminary Survey of Speech-Language Pathology Practice Patterns
Authors: Roitsch Jane , Prebor Jessica , Raymer Anastasia M. 
Published: July 2021

Purpose
Speech-language pathologists (SLPs) are often responsible for assessing cognitive disorders that affect communication for individuals with diagnosed or suspected acute or degenerative neurological conditions. However, consensus on appropriate assessment tools for various neurological disorders remains elusive. This preliminary survey was conducted to study current practices in the use of published and unpublished tools by SLPs when assessing cognitive-communication impairments across common neurologic conditions.

Method
An 18-item web-based survey was sent to SLPs through ASHA Communities and social media, asking them to select which cognitive assessment tools they use to evaluate the cognitive-communication status of individuals with Parkinson's disease, multiple sclerosis, dementia, stroke (i.e., cerebrovascular accident), and traumatic brain injury. The 100 SLPs who completed the online survey represent a spectrum of professionals seeing neurologic patients across the United States.

Results
Among the 100 responding SLPs, no unique pattern of assessment tool use was noted across neurologic disorders as indicated by a chi-square analysis. A common set of nonstandardized and observational assessment practices was reported most commonly, regardless of the neurologic condition.

Conclusions
This study shows consistent cognitive assessment practices by SLPs across various neurological conditions rather than unique protocols relevant to the patterns typical across disorders. However, the amount of clinical evaluations supported by informal observation and/or the completion of select subtests of standardized assessment tools is considerable. This preliminary information conflicts with principles of rigorous assessment and increases the risk of erroneous findings when identifying cognitive impairments. Further research into the decision-making process of clinician assessment selection is warranted to encourage consistent, evidence-based practice for persons with cognitive impairments. Better recognition of the limitations imposed by providing clinical services that impact the reliability and validity of cognitive assessments can drive future clinical practice policy and practice recommendations.
The distribution and origin of C2H in NGC 253 from ALCHEMI
Authors: Holdship J. , Viti S. , Martín S. , Harada N. , Mangum J. , Sakamoto K. , Muller S. , Tanaka K. , Yoshimura Y. , Nakanishi K. , Herrero-Illana R. , Mühle S. , Aladro R. , Colzi L. , Emig K. L. , García-Burillo S. , Henkel C. , Humire P. , Meier D. S. , Rivilla V. M. , van der Werf P. 
Published: July 2021

Context. Observations of chemical species can provide insights into the physical conditions of the emitting gas however it is important to understand how their abundances and excitation vary within different heating environments. C2H is a molecule typically found in PDR regions of our own Galaxy but there is evidence to suggest it also traces other regions undergoing energetic processing in extragalactic environments.
Aims. As part of the ALCHEMI ALMA large program, we map the emission of C2H in the central molecular zone of the nearby starburst galaxy NGC 253 at 1.6″ (28 pc) resolution and characterize it to understand its chemical origins.
Methods. We used spectral modeling of the N = 1−0 through N = 4−3 rotational transitions of C2H to derive the C2H column densities towards the dense clouds in NGC 253. We then use chemical modeling, including photodissociation region (PDR), dense cloud, and shock models to investigate the chemical processes and physical conditions that are producing the molecular emission.
Results. We find high C2H column densities of ∼1015 cm−2 detected towards the dense regions of NGC 253. We further find that these column densities cannot be reproduced if it is assumed that the emission arises from the PDR regions at the edge of the clouds. Instead, we find that the C2H abundance remains high even in the high visual extinction interior of these clouds and that this is most likely caused by a high cosmic-ray ionization rate.
The structurally conserved TELR region on shelterin protein TPP1 is essential for telomerase processivity but not recruitment
Authors: Sandhu Ranjodh , Sharma Madhav , Wei Derek , Xu Lifeng 
Published: July 2021

Significance
Telomerase directs the synthesis of new telomeric repeats at chromosome ends, enabling cells to overcome the end replication problem and to continue to divide. The shelterin protein TPP1 interacts with telomerase, promoting both telomerase recruitment and processivity (the addition of multiple telomeric repeats after a single substrate binding event). Here, we identify separation-of-function mutants of TPP1 that eliminate telomerase processivity but leave the telomerase recruitment function intact. When introduced into human cells in a homozygous manner, these mutations can induce critical telomere shortening and cellular senescence. Our observations therefore demonstrate that TPP1 stimulation of telomerase processivity is a key regulatory step in vivo for telomerase-mediated extension of telomeres and continued cell proliferation.
Non-Foster acoustic radiation from an active piezoelectric transducer
Authors: Rasmussen Curtis , Alù Andrea 
Published: July 2021

Significance
Many of the exciting wave phenomena found in acoustic metamaterials arise as a result of the collective response of subwavelength resonators. To widen the frequency range of these phenomena, it is necessary to understand the source of these bandwidth limitations and explore techniques that can overcome them. Here, we quantify the general tradeoff between size and bandwidth of passive acoustic resonators and show how this constraint can be overcome by actively loading them. As an example, we demonstrate a large bandwidth enhancement of a sonar transducer by connecting it to a specialized active non-Foster circuit. This important finding can have long-lasting impact in acoustic metamaterials for exotic sound interactions, paving the way to enhanced compact resonant acoustic devices.
Tradeoffs for a viral mutant with enhanced replication speed
Authors: Lanahan Matthew R. , Maples Robert W. , Pfeiffer Julie K. 
Published: July 2021

Significance
Viruses have characteristic replication speeds within a given cell type. Many factors can slow the rate of viral replication, including attenuating mutations and host antiviral responses. However, it has been unclear whether it would be possible to “speed up” a virus that already replicates efficiently in a specific cell type. Here, we selected for a mutant coxsackievirus with enhanced replication speed by sequentially harvesting the very earliest progeny in multiple rounds of selection. A single mutation conferred the fast-replication phenotype. While this mutant virus has enhanced replication in cultured cells due to faster genome uncoating, it was attenuated in mice. These results highlight selective pressures that shape viral populations in different environments.
Quantitative perspectives in Cognitive Linguistics
Authors: Janda Laura A. 
Published: July 2021

Abstract
As a usage-based approach to the study of language, cognitive linguistics is theoretically well poised to apply
quantitative methods to the analysis of corpus and experimental data. In this article, I review the historical circumstances that
led to the quantitative turn in cognitive linguistics and give an overview of statistical models used by cognitive linguists,
including chi-square test, Fisher test, Binomial test, t-test, ANOVA, correlation, regression, classification and regression
trees, naïve discriminative learning, cluster analysis, multi-dimensional scaling, and correspondence analysis. I stress the
essential role of introspection in the design and interpretation of linguistic studies, and assess the pros and cons of the
quantitative turn. I also make a case for open access science and appropriate archiving of linguistic data.
Construction in conversation
Authors: Hsieh Chen-Yu Chester , I-Wen Su Lily 
Published: July 2021

Abstract
Although the Construction Grammar (CxG) model has yielded fruitful findings, the role that pragmatics plays in
language has not yet been fully considered in this theoretical framework. The recent development of spoken corpora, however,
enables construction grammarians to develop a new approach called Interactional Construction Grammar, which incorporates
interactional factors into CxG analysis to account for patterns that involve interpersonal functions and global contexts. Adopting
this approach, the present study attempts to examine the use of a complement-taking mental predicate xiangshuo in
Taiwan Mandarin conversation and analyze the co-occurrence patterns of this cognitive verb with different subjects. We identify
three sequential patterns in which xiangshuo most frequently occurs, including account-giving,
contrast-projecting and involvement-constructing, and argue that only by taking into account the sequential context and
interactional function can the distribution patterns of subjects and particles that recurrently collocate with
xiangshuo be explained.
Challenges and solutions in test adaption
Authors: Enns Charlotte , Kolbe Vera , Becker Claudia 
Published: July 2021

Abstract
Sign language assessment tools are important for professionals working with DHH children to measure sign language
development and competence. Adaptation of an existing test can be a solution when initiating assessment in a sign language
community; the adaptation process must adhere to key principles and procedures. We introduce the principles of test adaptation and
outline the challenges we faced in adapting the British Sign Language Production Test (Herman, Grove, Holmes, Morgan, Sutherland & Woll 2004) to German Sign Language and American Sign
Language. Challenges included decisions regarding the normative sample, the use of terminology, and variations in the scoring
protocols to fit with each language. The steps taken throughout the test adaptation process are described, together with a
comparison of parallels and differences. We conclude that test adaptation is an effective method of developing practical tools for
sign language assessment and contributes to a better understanding of sign language development.
Perturbation spectra and renormalization-group techniques in double-field inflation and quantum gravity cosmology
Authors: Anselmi Damiano 
Published: July 2021

Abstract
We study primordial cosmology with two scalar fields that participate in
inflation at the same time, by coupling quantum gravity (i.e., the theory R+R2+C2 with the fakeon prescription/projection for C2) to a
scalar field with a quadratic potential. We show that there exists a
perturbative regime that can be described by an asymptotically de Sitter,
cosmic RG flow in two couplings. Since the two scalar degrees of freedom mix
in nontrivial ways, the adiabatic and isocurvature perturbations are not RG
invariant on superhorizon scales. It is possible to identify the correct
perturbations by using RG invariance as a guiding principle. We work out the
resulting power spectra of the tensor and scalar perturbations to the NNLL
and NLL orders, respectively. An unexpected consequence of RG invariance is
that the theory remains predictive. Indeed, the scalar mixing affects only
the subleading corrections, so the predictions of quantum gravity with
single-field inflation are confirmed to the leading order.
Affordances of Plurilingual Instruction in Higher Education: A Mixed Methods Study with a Quasi-experiment in an English Language Program
Authors: Galante Angelica 
Published: July 2021

Abstract
While calls have been made for a multi/plural turn in Applied Linguistics, there remains a paucity of research investigating instruction that addresses the turn and its effects on student learning compared with monolingual one-language-only instruction. This study examines the effects of plurilingual instruction on students’ plurilingual and pluricultural competence (PPC) relative to monolingual English-only instruction. Moreover, it investigates potential additional affordances. Seven teachers in an English for Academic Purposes (EAP) program in a Canadian university taught two intact groups for four months: treatment (plurilingual instruction, n = 79) and comparison (monolingual instruction, n = 50) groups. Results from pre- and post-tests of the PPC scale show that students in the treatment group had higher PPC levels over time relative to students in the comparison group. Moreover, analyses of diaries and focus groups with students in the treatment group show that plurilingual instruction offers affordances such as cognition, empathy, and criticality. These results are significant as they suggest that plurilingual instruction may be more effective than monolingual instruction in the development of PPC and it offers several additional affordances.