bluuebunny/crossref_metadata_2025_split huggingface dataset:
EVALUASI PRODUKTIVITAS ALAT GALI MUAT TERHADAP PENCAPAIAN TARGET PRODUKSI OVERBURDEN DI PT RIMAU ENERGY MINING, SITE DESA PUTUT TAWULUH, KECAMATAN DUSUN TIMUR, KABUPATEN BARITO TIMUR, PROVINSI KALIMANTAN TENGAH
Authors: Firdaus M. Azhari , Saismana Uyu , Annisa Annisa 
Published: February 2021

Produktivitas merupakan kemampuan alat melakukan kegiatan produksi berdasakan waktu efektif dalam satuan waktu (1 jam). Produktivitas alat gali muat dipengarahui oleh beberapa parameter yaitu cycle time, bucket fill factor, swell factor, effective utilization. Target produktivitas alat gali muat PC 800 SE sebesar 265 BCM/jam dan target produksi dalam 1 shift adalah 1432,71 BCM.Metodologi yang digunakan dalam penelitian ini adalah observasi pada kegiatan pemindahan overburden. Observasi dilakukan baik pada alat mekanis (waktu siklus, waktu tunda, dan bucket fill factor) maupun pada sifat material (kepadatan dan swell factor). Data yang dikumpulkan dari pengamatan kemudian diolah menggunakan komputer untuk mendapatkan hasil produksi aktual.Berdasarkan pengamatan dan hasil pengolahan didapatkan bahwa rata-rata produksi 1001,44 BCM, rata-rata produktivitas 223,5 BCM/jam, rata-rata cycle time 0,43 menit, rata-rata effective utilization (EU) 54%, rata-rata waktu efektif dalam 1 shift 3,46 jam. Nilai effective utilization (EU) dipengaruhi oleh hambatan yang dapat dihindari dan hambatan tidak dapat dihindari. Kata-kata kunci: effective utilization, produksi, produktivitas
Engineering sub-2 nm ultrasmall high-entropy alloy nanoparticles with extremely superior performance for hydrogen evolution catalysis
Authors: Xia Dingguo , Feng Guang , Ning Fanghua , Song Jin , Shang Huaifang , Zhang Kun , Ding Zhengping , Gao Peng , Chu Wangsheng 
Published: February 2021

Abstract
The development of intrinsically effective and low-cost catalysts is critical for the large-scale commercial applications of electrocatalytic hydrogen production. Although various electrocatalysts have demonstrated high activities for hydrogen evolution reaction (HER), it remains a formidable challenge to develop an extremely efficient and durable catalyst for practical use, especially in acidic media. Here, we report quinary ultrasmall NiCoFePtRh high-entropy alloy (us-HEA) nanoparticles (NPs) with extremely superior performance for HER. The us-HEA NPs are well dispersed on the carbon supports, with an average diameter of 1.68 nm, which is the smallest size in the reported HEAs. The us-HEA/C achieves an ultrahigh mass activity of 28.3 A mg-1noble metals (much higher than that of other reported advanced catalysts) at -0.05 V (vs the reversible hydrogen electrode, RHE) for HER in 0.5 M H2SO4 solution, which is 40.4 and 74.5 times higher than those of the commercial Pt/C and Rh/C catalysts, respectively. Moreover, the us-HEA/C demonstrates the highest reported turnover frequency of 30.1 s−1 at 50 mV overpotential (41.8 times higher than that of the Pt/C catalyst) and excellent stability with no decay after 10,000 cycles. Both operando X-ray absorption spectroscopy and theoretical calculations reveal the true active sites and a synergistic effect among five elements, which endow us-HEA/C with significantly enhanced HER activity. This work not only provides a general and facile strategy for synthesizing us-HEA NPs, highlights HEAs as sufficiently advanced materials in energy electrocatalysis, but also acts as a guidance for elucidating the actual reaction process and catalytic mechanism of complex multi-element systems.
Sec3 Exocyst Component Knockdown Inhibits Axonal Formation and Cortical Neuronal Migration During Brain Cortex Development
Authors: Plonka Florentyna Bustos , Sosa Lucas , Quiroga Santiago 
Published: February 2021

Abstract
During neuronal development cell polarization is of vital importance. The establishment of polarity necessitates initial axonal outgrowth in concomitance with the addition of new membrane to the axon’s plasmalemma. Axolemmal expansion occurs by exocytosis of plasmalemmal precursor vesicles primarily at the neuronal growth cone membrane. The multiprotein exocyst complex drives spatial location and specificity of vesicle fusion at plasma membrane. However, the specific participation of its different proteins on neuronal differentiation has not been fully established. In the present work we analyzed the role of Sec3, a prominent exocyst complex protein on neuronal differentiation. Using mice hipocampal primary cultures we determined that Sec3 is expressed in neurons at early stages prior to neuronal polarization. Furthermore, we determined that silencing of Sec3 in mice hippocampal neurons in culture precluded polarization. Moreover, using in utero electroporation experiments, we determined that Sec3 knockdown affected cortical neurons migration and morphology during neocortex formation. Our results demonstrate that the exocyst complex protein Sec3 plays an important role in axon formation in neuronal differentiation and the migration of neuronal progenitors during cortex development.
Long-Term Study of Borrelia and Babesia Species Distribution in Ixodes Ricinus and Dermacentor Recticulatus Ticks Removed From Humans in Poland, 2016-2019
Authors: Welc-Falęciak Renata , Bednarska Małgorzata , Hamera Adrianna , Religa Emilia , Poryszewka Milena , Mierzejewska Ewa , Pawełczyk Agnieszka 
Published: February 2021

Abstract
Monitoring changes in the prevalence of different Borrelia genospecies/ species in ticks might be an important indicator of risk assessment and of differences in pathogenicity in humans. Furthermore, the evaluation of pathogens in feeding ticks represents the risk of human exposure better than studies on questing ticks. The objective of our study was to assess the prevalence and distribution of Borrelia and Babesia species in ticks removed from humans, in a larger sample collected for several months during four years of studies. We confirmed high Borrelia prevalence, including B. miyamotoi, in ticks removed from humans as well as the shift in Borrelia genospecies/ species frequency of occurrence during the four-year study. Despite the fact that Babesia prevalence was relatively low, the majority of tested isolates are considered to be pathogenic for humans. The results of our study have also shown that Borrelia and Babesia coinfections in ticks are more common in Borrelia-infected ticks. Even if the overall risk of developing Lyme borreliosis after a tick bite in Europe is rather low, the knowledge of prevalence and distribution of Borrelia and Babesia species in ticks might be an important indicator of both tick-borne disease risk and pathogenicity assessment.
The Manifestations of Social Maladjustment in Children With leukemia at Different Ages: A Descriptive Qualitative Study based on Phenomenology
Authors: Tang Xinyue , Mo Lin , Liu Qian , Liu Yixuan , Yu Lu , Liu Yang , Gao Chunhai 
Published: February 2021

Abstract
Background Leukemia is a pediatric malignancy with the highest incidence rate and large onset age span. Children with leukemia at different ages show various social maladjustments after illness, which are mainly reflected in psychological and behavioral changes. It is of great significance to improve children's social adaptation level and purposefully prevent children from having social adaptation problems. Objective To describe the social adaptation problems faced by Chinese children with leukemia at different ages, and to provide the basis for formulating targeted preventive intervention strategies. Method The purpose sampling method was adopted to conduct semi-structured interviews on 20 Chinese children with leukemia and their main caregivers, and the Colaizzi phenomenological research method in the qualitative research was used to organize and analyze the data. Results The existing social adaptation problems of children with leukemia at different ages were summarized. In terms of psychological maladjustment, children with leukemia aged 2~7 years showed "fear and excessive attachment"; Children with leukemia aged 8-18 years are characterized by "Impatience, irritability and anxiety". In terms of behavioral maladjustment, children with leukemia aged 2~7 years have the problem of "less independent behavior" and "dependence on electronic products"; Children with leukemia aged 8-18 years showed "learning obstruction" and "indulging in mobile games". Conclusions Develop targeted intervention strategies based on the physical and mental characteristics of children with leukemia at different ages to improve their existing social adaptation problems. Pay attention to early intervention in the social adaptation of children with leukemia. Predictably improve the social adaptation level of children to prevent more adaptation problems, so that children can smoothly return to their families and society and improve their quality of life in the long term.
Establish Reference Intervals of Complete Blood Count for Twin Pregnancy
Authors: Zeng Yifan , Li Lei , Mao Man , Liang Xinghua , Chen Min , He Wenyin , Xia Yong 
Published: February 2021

Abstract
Background: Twin pregnancy is of high risk, which increased in recent years. Establishment of reference intervals of complete blood count (CBC) for twin-pregnant women during pregnancy might help for the properly prognosis of adverse outcomes in twin pregnancy. Methods: We screened out 253 cases of twin pregnancy reference cohort from 1153 twin pregnancy after the complications and adverse pregnancy outcomes were excluded. Complete blood count data were collected during the mid- and late-term of pregnancy and analyzed by SPSS to establish the reference intervals of peripheral blood of twin pregnancy. Results: The RBC, HGB, HCT, and PLT were lower in twin pregnant women than those in healthy nulligravida women during gestation, while the levels of WBC, NEU, and NEU% increased, especially in the mid-term. The reference intervals of late-term pregnancy validated by using 20 samples of twin pregnancy, then utilized for figuring out the distinctive characteristics of CBC with preterm birth (PTB) pregnancy. Absolutes of WBC and NEU increased in PTB pregnancy using our established reference intervals, implying they might be prognosis indicators of this adverse outcome. Conclusion: Establishing the reference interval of blood cell-related indicators of normal twin pregnancy is helpful for the monitoring and prognosis of PTB.
Impact of COVID-19 on Health-Related Behaviours, Well-Being and Weight Management
Authors: Avery Amanda , Toon Josef , Kent Jennifer , Holloway Laura , Lavin Jacquie , Bennett Sarah-Elizabeth 
Published: February 2021

Abstract
Background: Weight management is complex even in times of stability. Supporting individuals to develop strategies to maintain a healthier weight is beneficial. This paper reports data from an ongoing mixed-methods study describing the impact the COVID-19 lockdown situation had on people engaged in weight management. Information on health-related behaviours and well-being was captured from surveys completed by Slimming World (SW) members 0-4 weeks after joining providing pre-joining and baseline (T0&T1) data, and after 3 (T2) and 6 months (T3-during COVID-19). Representative samples from the general population, not attending a weight management service, completed the same questionnaires.Results: 1884 SW members completed the baseline survey and 222 completed all three surveys up to May 2020, achieving a weight loss of 7.7±7.5% during this time. SW members were able to maintain most of the positive health-related behaviour changes they had made since joining, including increased fruit and vegetable consumption (p<0.001), having fewer sugary drinks (P<0.001), cooking from scratch more (p<0.001) and increasing activity levels (p<0.001). During the COVID-19 situation members were still reporting improvements in all behaviours compared to before joining and had healthier scores than the general population on all but alcohol intake, although still within guidelines. Qualitative data indicated that the COVID-19 situation created various challenges to managing weight for both groups with fresh foods harder to access, comfort eating, drinking more alcohol, eating more sugary foods and snacking through boredom. However, some people also reported having more free time enabling better planning, more time to cook from scratch and increased physical activity.Conclusions: The findings highlight the value of supporting individuals to develop sustainable behaviour changes and a level of resilience to draw upon and manage their weight even in challenging times.
Relationship Between Sleep Duration and Stroke in Middle-Aged and Elderly in Guiyang: A Cross-Sectional Survey
Authors: Liu Li , Yang Jingyuan , Wang Junhua , Nie Meng , Wang Ziyun , Guan Han , Hu Jin , Hong Feng 
Published: February 2021

Abstract
Background: With over 2 million new cases annually, stroke is associated with the highest disability-adjusted life-years lost of any disease in China. The relationship between sleep time and stroke has not been concluded yet. To study the relationship between sleep duration and stroke in middle-aged and elderly in Guiyang, China. Methods: This study was a cross-sectional survey carried out in 40-99-years-old permanent residents in Guiyang. Yunyan, Wudang, and Baiyun districts and Xiuwen County were selected by stratified multilevel sampling for a face-to-face survey. Demographics, stroke, sleep behavior, and health behavior were collected. Multivariable logistic regression models were used to gradually adjust the association between sleep duration and stroke for possible confounding factors. Results: A total of 5065 participants were included, and 126 (2.5%) had a stroke. Insufficient sleep (<7 h) was observed in 11.0%, sufficient sleep (7-9 h) in 69.4%, and long sleep (>9 h) in 19.6%. Sleep duration and stroke prevalence showed a U-shaped distribution. When taking the sleep duration of 7-9 h as reference, sleep duration >9 h was associated with stroke (all P<0.05) in the univariable model (OR=2.68, 95%CI: 1.83-3.93) and in the multivariable models 1 (OR=2.35, 95%CI: 1.59-3.47), 2 (OR=2.27, 95%CI: 1.53-3.37), 3 (OR=2.25, 95%CI: 1.51-3.33), and 4 (OR=2.11, 95%CI: 1.39-3.19). There were no significant differences between the <7 and 7-9 h groups (P>0.05). Conclusion: Long sleep duration (>9 h) is independently associated with stroke in middle-aged and elderly people in Guiyang.
A New Approach in DENV Diagnostic based on Linear Peptides Obtained by Phage Display
Authors: Burciaga-Flores Mirna , Camacho-Villegas Tanya A. , Lugo-Fabres Pavel H. , Gutiérrez-Ortega Abel , Muñoz-Medina José Esteban , Elizondo-Quiroga Darwin E. 
Published: February 2021

Abstract
Dengue is a viral disease caused by any of the four distinct dengue virus (DENV) serotypes that circulate in many parts of the world. DENV now co-circulates with Zika and Chikungunya viruses (ZIKV and CHIKV) in many regions of the Americas. Having this in mind, plus the fact that DENV clinical diagnosis persists as a difficult task, due to the similarity in symptoms, as well as false-positive results by the cross-reactivity of the IgG and IgM against these three viruses, correct identification of DENV at an early stage of the disease is essential to minimise transmission and prevent potentially devastating sequelae. Here, by phage display, we isolate specific peptides for dengue virus NS1 protein. The specificity of the linear peptides as diagnostic tools for DENV NS1 protein in sera samples was investigated, and the selected peptides showed the ability to recognise DENV, and no cross-reactivity was shown.
Moreover, in silico analysis was performed to assess the possible binding modes of these peptides to DENV-NS1, using a molecular docking approach. These peptides are suitable for use in an ELISA assay for dengue virus detection in human serum and the possibility to adapt these peptides to PoC platforms.
Wireless Communication for Flying Cars
Authors: Saeed Nasir , Al-Naffouri Tareq Y. , Alouini Mohamed-Slim 
Published: February 2021

Abstract
The existing ground-based transportation systems suffer from various challenges, mainly the high cost of infrastructure development, limited land space, and the growing urban population. Therefore, the automotive and aviation industries are collaborating to develop flying cars, also knows as electric vertical takeoff and landing aircrafts (eVTOLs). These eVTOLs will enable reliable and rapid urban and suburban transportation. Safe operation of eVTOLs will require well-developed wireless communication networks. However, existing communication technologies need advancement to provide services to flying cars. We report various potential solutions that are feasible for communication among the eVTOLs and with the ground. These possibilities include on-ground three-dimensional cellular networks, tethered balloons, high altitude platforms, and satellites.
Temporal Structure of Brain Oscillations Is A Biomarker of Pain and Predicts Learned Nocebo Responses.
Authors: Thomaidou Mia A. , Blythe Joseph S. , Houtman Simon J. , Veldhuijzen Dieuwke S. , Laarhoven Antoinette I. M. , Evers Andrea W. M. 
Published: February 2021

Abstract
This study aimed to identify electrophysiological biomarkers of nocebo-augmented pain. Nocebo hyperalgesia (i.e., increases in perceived pain resulting from negative expectations) was induced in 36 healthy participants through classical conditioning and negative suggestions. In a baseline phase, participants received high thermal pain stimulations. During acquisition, participants learned to associate an inert gel applied to their forearm with high pain, relative to a moderate intensity control stimulus administered without gel. During evocation, nocebo and control stimuli were both accompanied by moderate pain to measure nocebo responses. Electroencephalography was recorded during rest (pre and post nocebo acquisition) and during pain stimulation (baseline, nocebo acquisition and evocation). Nocebo hyperalgesia led to pre- to post-acquisition increases in long-range temporal correlations (LRTC), with beta-band alterations being negatively associated with nocebo magnitudes. Moreover, individuals with strong LRTC at rest showed larger nocebo responses than those with weaker LRTC. Nocebo acquisition trials showed reduced alpha power. Alpha power was higher while LRTC were lower during nocebo-augmented pain, compared to baseline. By involving LRTC, these findings support nocebo learning theories and highlight a role of nocebo-induced cognitive processing. This study provides novel insights into neural underpinnings of nocebo hyperalgesia, a phenomenon that greatly impacts the experience of pain.
The Association Between Employment Status and Timely Initiation of Infant Complementary Feeding Practice in Addis Zemen Town, Ethiopia, 2018.
Authors: Kassie Bekalu , Degu Genet , Tarekegn Teklemariam 
Published: February 2021

Abstract
Background

Complementary feeding is giving other foods or fluids to infants in addition to breast milk at six months of age. For better health and development of children, it should be timely (at six months of age). Thus, this study aimed to assess timely initiation of complementary feeding and associated factors among mothers with children aged 6–23 months in Addis Zemen Town.
Methods

A Community based cross-sectional study design was conducted from March 21 to April 10, 2018. Researchers recruited four hundred sixteen mothers whose child was aged from 6 to 23 months by systematic random sampling technique. We used interviewer-administrated questionnaire and then the data were coded and entered to EpiData version 4.2. It was exported to SPSS version 23 for analysis. Binary logistic regression model was fitted and variables p-values < 0.05 with multi-variable logistic regression analysis were considered as statistically significant at 95% confidence interval (CI). Adjusted odds ratio (AOR) was used to measure the strength of association.
Result

Timely initiation of complementary feeding was 57.7% with 95% CI (52.9, 62.3). In this study Being employed (AOR 2.34(1.07–5.16), visit antenatal care clinic four times and above (AOR 2.36(1.44, 3.85)), having good knowledge on complementary feeding (AOR 3.47(2.20, 5.48)), and having favorable attitude towards complementary feeding practice (AOR 3.87(2.46, 6.11) were found to be statically significantly associated with timely initiation of complementary feeding practice.
Conclusion

Timely initiation of complementary feeding practice was lower than WHO cut of point. Educate women, enhance antenatal visits and work to increase mothers’ knowledge are recommended. Additionally, special focus is better to be given for unemployed mothers.
Eight Months Into The COVID-19 Outbreak, Whether This Pandemic Still Psychologically Affected Convalescent Psychiatric Patients: A Cross-Sectional Study.
Authors: Ren Xin , Huang Wanli , Pan Huiping , Wang Xinwei , Huang Tingting , Ma Yongchun 
Published: February 2021

Abstract
Background

This study aimed to find out eight months into the COVID-19 outbreak, how much psychological effect was experienced by convalescent psychiatric patients, and identify the potential risk and protective factors related to their psychological response.
Methods

Data from 136 convalescent psychiatric patients were collected. We used binary logistic regression analyses to identify participants’ SRQ score and the factors associated with it.
Results

There were 47 (34.5%) participants scored eight or higher. Working or marital status and annual income were significantly associated with a higher score in SRQ. Similarly, sleep duration, interpersonal relationship, exercise time, special events, and general condition were linked to SRQ grade.
Conclusions

Eight months into the COVID-19 pandemic, this widespread virus psychologically impacted convalescent psychiatric patients. This result was related to less annual income, which stressed the necessity to provide closer follow-up and financial support in this crisis's late stage.
The Prophylactic Effect of Silver Sulphadiazine and Chloroquine in-situ Gel Formulation Against Rodent Malaria Parasite Plasmodium Berghei
Authors: Zelai Noha 
Published: February 2021

Abstract
Background: Despite the technological advances made in the pharmaceutical field, globally, malaria remains one of the major causes of mortality. The resistance of malaria parasites to conventional drugs is one of the primary challenges facing researchers. Therefore, the aim of this study is to examine the validity of a single dose in-situ gel formulation of chloroquine and silver sulfadiazine against rodent model malaria, Plasmodium berghei.Results: Following administration of the free or gel drug formulations to mice four days before infection, the in-situ gelled formulation were not found to improve drug parasitaemia nor increase the life span of the infected mice. This may be attributed to the initial high burst of drug release within the initial days of treatment before infection. Conclusions: Additional studies are warranted to determine the timing of the malarial drug burst, and to design the prophylactic interval based on the drug pharmacokinetics and their metabolites.