bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enlaces Matrimoniais e Desquites: Casamento e Relações de Gênero em Processos Judiciais em Parnaíba/PI nas Décadas de 1960 e 1970
Authors: Araújo de Freitas Ana Beatriz 
Published: October 2021

Resumo: Este trabalho expressa os primeiros passos de uma pesquisa que busca, a partir de processos judiciais de desquite, compreender o cotidiano de famílias na cidade de Parnaíba/PI, nas décadas 1960 e 1970, além de analisar a construção dos papeis de gênero presente nos autos desses processos. O texto divide-se em dois momentos. No primeiro, trataremos da instituição casamento e mais especificamente sobre o desquite, tendo como fundamento o Código Civil Brasileiro de 1916. Posteriormente, analisaremos dois casos a fim de percebermos de que forma se deram as relações de gênero nos autos processuais.Palavras-chave: Desquite. Cotidiano. Gênero.
SISTEM INFORMASI TERINTEGRASI TUGAS AKHIR/SKRIPSI BERBASIS WEB (Studi Kasus: Jurusan Sistem Informasi Institut Informatika dan Bisnis Darmajaya)
Authors: Kurniawan Hendra , Bondowoso Wicakso Bandung 
Published: October 2021

Sistem informasi terintegrasi tugas akhir/skripsi ini memungkinkan atau memberikan fasilitas kepada beberapa aktor dapat saling berinteraksi sesuai dengan standar operasional prosedur yang dimiliki oleh masing-masing aktor dan berbasis dokumen elektronik. Adapun aktor yang terlibat didalamnya adalah Mahasiswa, Kelompok Bidang Keilmuan (KBK), Dosen Pembimbing, Dosen Penguji, Biro Administrasi Akademik dan Kemahasiswaan (BAAK), Sekretaris Jurusan serta Ketua Jurusan. Sistem ini memuat aktifitas dimulai dari pengajuan judul skripsi/tugas akhir, penentuan dosen pembimbing, pembuatan surat keputusan pembimbing, bimbingan skripsi, pendaftaran dan penjadwalan seminar proposal skripsi/tugas akhir, penentuan pembahas pada seminar proposal skripsi/tugas akhir, pendaftaran dan penjadwalan sidang skripsi/tugas akhir dan penilaian sidang skripsi/tugas akhir berikut dengan lampiran dokumen-dokumen pada setiap aktifitasnya. Sistem Informasi ini dibangun menggunakan metode Terstruktur (waterfall model). Sistem dibuat dengan menggunakan HTML, CSS, PHP, Bootstrap dan MySql. Hasil dari penelitian yang dicapai menciptakan sebuah web sistem diharapkan membantu jurusan sistem informasi dalam pengolahan dokumen dan interaksi yang berkualitas.Kata kunci: Sistem Informasi; tugas akhir; skripsi; E-Document
Rancang Bangun Sistem Pakar Troubleshooting Hardware Komputer Berbasis Android
Authors: Akbar Rizal Moamar 
Published: October 2021

Kerusakan pada komputer merupakan sebuah masalah yang menggangu. Terutama bagi seseorang yang pekerjaannya banyak bergantung kepada komputer ataupun laptop. Diagnosa kerusakan sebuah sistem merupakan pekerjaan yang komplek. Komplek karena tidak hanya diperlukan pengetahuan yang cukup, namun diperlukan juga pengalaman yang memadai. Terkait, permasalahan yang terjadi peneliti merancang sebuah aplikasi yang dibuat guna untuk mengembangkan metode pembelajaran yang baru dengan informasi-informasi yang didapat dari para ahli pakar, sehingga diharapkan dengan adanya aplikasi ini memberikan suatu teknik pembelajaran yang mudah dipahami oleh para pelajar dan masyarakat serta dapat digunakan pada semua perangkat Android. Metode yang digunakan dalam penelitian ini adalah metode Forward Chaining dengan teknik decision tree, pustaka, Jurnal dalam pengumpulan data. Sehingga Aplikasi Sistem Pakar Troubleshooting hardware komputer ini dapat digunakan sebagai media pembelajaran bagi semua kalangan baik itu pelajar maupun masyarakat. Kesimpulaan dari penelitian ini adalah mengetahui tingkat kelayakan sistem pakar untuk mendiagnosa kerusakkan komputer pada perangkat smartphone dengan sistem operasi android. Serta, memberikan informasi solusi alternatif kepada user dalam menemukan letak permasalahan yang terjadi pada komputernya. Kata Kunci: Rancang Bangun, Android, Sistem Pakar, Hardware
Heat-insulating non-autoclaved lightweight concrete with hydraulic ash removal
Authors: Kudyakov A. I. , Steshenko A. B. , Dushenin N. P. , Ryabtseva N. E. 
Published: October 2021

The paper presents research results of natural hardening of lightweight concrete with aluminosilicate ash generated by the Thermal Power Plant in Seversk (Tomsk, Russia). Today, it is necessary to develop effective building materials with improved operational properties by using local natural and technogenic raw materials. The acceleration of the structure formation and required plasticity for a transportation and molding of lightweight concrete products are achieved by using finely dispersed aluminosilicate minerals and plasticizers for natural hardening of lightweight concrete. The concrete mixture and lightweight concrete are studied in the TSUAB laboratory accredited in accordance with national standard requirements. The optimum content of hydraulic ash in lightweight concrete mixture is 10–15 wt.%. the compressive strength lightweight concrete with D400 density increases by 26−66 % after 28-day curing, when adding the Relamix T-2 plasticizer and ash from the Thermal Power Plant. Its water absorption reduces by 30 wt.% with insignificant decrease in thermal conductivity. Technological solutions are developed for the production of lightweight concrete with ash ash and slag materials for wall structures in individual housing construction.
Safety and Pharmacokinetics of Intravesical Chitosan/Interleukin-12 Immunotherapy in Murine Bladders
Authors: Nguyen Khue G. , Wagner Ethan S. , Vrabel Maura R. , Mantooth Siena M. , Meritet Danielle M. , Zaharoff David A. 
Published: October 2021

BACKGROUND: Intravesical administration of interleukin 12 (IL-12) co-formulated with the biopolymer, chitosan (CS/IL-12), has demonstrated remarkable antitumor activity against preclinical models of bladder cancer. However, given historical concerns regarding severe toxicities associated with systemic IL-12 administration in clinical trials, it is important to evaluate the safety of intravesical CS/IL-12 prior to clinical translation. OBJECTIVE: To evaluate the pharmacokinetics as well as the local and systemic toxicities of intravesical CS/IL-12 immunotherapy in laboratory mice. METHODS: Local inflammatory responses in mouse bladders treated with intravesical IL-12 or CS/IL-12 were assessed via histopathology. Serum cytokine levels following intravesical and subcutaneous (s.c.) administrations of IL-12 or CS/IL-12 in laboratory mice were compared. Systemic toxicities were evaluated via body weight and liver enzyme levels. RESULTS: Intravesical IL-12 and CS/IL-12 treatments did not induce significant local or systemic toxicity. IL-12 dissemination and exposure from intravesical administration was significantly lower compared to s.c. injections. Weekly intravesical CS/IL-12 treatments were well-tolerated and did not result in blunted immune responses. CONCLUSIONS: Intravesical CS/IL-12 is safe and well-tolerated in mice. In particular, the lack of cystitis and acute inflammation justifies continued investigation of intravesical CS/IL-12 immunotherapy in larger animals and patients with bladder cancer.
Falls, Fear of Falling, and Preventive Measures in Huntington’s Disease: The Perspectives of Individuals with Huntington’s Disease and Caregivers in Long-Term Care
Authors: Kalkers Kristel , Schols Jos M.G.A. , van Zwet Erik W. , Roos Raymund A.C. 
Published: October 2021

Background: Falls are common in Huntington’s disease (HD), which can have serious consequences and may therefore lead to fear of falling (FoF). There is little knowledge about falls or FoF in individuals with HD or about formal and informal caregivers’ fear about falls in individuals with HD. Objective: To explore prevalence of falls, FoF and fall preventive measures both those applied and those not included in managing falls in individuals with HD and their formal and informal caregivers, and to identify the relationship between FoF and, anxiety, awareness and cognitive functioning respectively. Methods: In a multi-center observational cross-sectional study, care-independent and -dependent individuals with HD and their formal and informal caregivers were recruited from six Dutch nursing homes specialized in HD. The participants were assessed by means of questionnaires enquiring about falls, FoF, awareness of fall risk, cognition, anxiety and fall preventive measures. Results: For all included 158 individuals with HD, the fall prevalence over the last 30 days was 28.8%. The prevalence of FoF in individuals with HD, formal caregivers and informal caregivers was 47.6%, 25.6%, and 63.5%, respectively, for care-independent individuals with HD and 46.9%, 26.3%, and 62.0%, respectively, for care-dependent individuals with HD. Anticipatory awareness of fall risks and gender are predictors of FoF in care-independent individuals with HD, though not in the care-dependent group. A combination of fall preventive measures is used in most individuals with HD. Conclusion: Fall prevalence is high and FoF is common in individuals with HD and their caregivers. Gender and anticipatory awareness are risk factors for FoF. In addition to the use of individual multifactorial fall prevention strategies, it is important to support both formal and informal caregivers in coping with falls
Improving Patient Outreach by Defining Telehealth Suitability in a Tertiary Huntington’s Disease Clinic
Authors: Lee Sean J. , Hale Lisa M. , Huitz Elizabeth , Claassen Daniel O. , McDonell Katherine E. 
Published: October 2021

Background: The COVID-19 pandemic has increased the need for remote healthcare options among patients with Huntington’s disease (HD). However, since not every HD patient is suitable for telehealth, it is important to differentiate who can be seen virtually from who should remain as in-person. Unfortunately, there are no clinical guidelines on how to evaluate HD patients for telehealth eligibility. Objective: To standardize the teleneurology selection process in HD by implementing a screening tool that accounts for patient-specific factors. Methods: We organized various indications and contraindications to teleneurology into a flowchart. If any indications or contraindications were met, patients were assigned to telehealth or maintained as in-person, respectively. If no indications or contraindications were met, patients were given the option of telehealth or in-person for their upcoming appointments. In two implementation cycles, we tested this screening tool among all HD patients scheduled for clinic visits, aided by chart review and phone interview. Results: In a cohort of 81 patients, telehealth acceptance among eligible patients increased from 45.0%to 83.3%. Frequency of telehealth visits increased from a pre-intervention baseline of 12.8%to 28.2%. Conclusion: Teleneurology utilization among HD patients more than doubled across our study. Our intervention promotes consistency and patient-centeredness in HD clinical care and streamlines the overall telehealth selection process. Future studies can seek to reduce telehealth no-shows and also evaluate the utility of the motor and psychiatric criteria included in our screening tool.
Group-Based Restorative Care Model For Improving Social Interaction Among Elderly In Nursing Home
Authors: Riasmini Ni Made 
Published: October 2021

An increasing proportion of the elderly population should be aware, because the main manifestation of the aging process experienced by the elderly can reduce ability to work, and the ability to perform the activity and social interaction with their environment. To overcome this problem, a group-based restorative care model is needed to increase the social interaction among elderly. This study aimed to obtain an overview of the effectiveness of the group-based restorative care model on the social interactions among elderly in nursing homes. The research design used a quasi-experimental with control group design with a sample size of 66 elderly who have been living in nursing home in the DKI Jakarta area. Data analysis used t-test and Mancova test. The results of the study found that there were differences in social interaction before and after the intervention in the intervention group, while in the control group there were no differences; there were differences in social interaction after the intervention between the intervention group and the control group; there was an effect of social support on social interaction. The recommendation is the group-based restorative care model can be used as a model for empowering the elderly in carrying out various activities in various health care settings in the community
ДУХОВНЕ ПРОБУДЖЕННЯ ОСОБИСТОСТІ: ХАРАКТЕРНІ ОЗНАКИ, УМОВИ ТА ЧИННИКИ
Authors: Тюріна Т. Г. 
Published: October 2021

У статті розкрито поняття «духовне пробудження» особистості, використовуючи християнський, духовно-філософський, ноосферний і науковий підходи.
Представлено авторське визначення цього поняття, де духовно пробуджена людина трактується як особистість з космопланетарним рівнем свідомості, носій духовності і духовних знань, активно діюча інформаційно-енергетична одиниця Всесвіту, через яку транслюються духовні космічні енергії. Головне призначення духовно пробудженої людини – одухотворяти світ, привносити у життя людства красу і гармонію, любов і добро, мир і істину, сприяючи його еволюції. Духовний саморозвиток, духовне зростання є вищим смислом її життя.
Розглянуто образи духовно пробудженої людини та їх характерні особливості у творчості видатних вчених: філософів, психологів ХХ–ХХІ століття (А. Маслоу, М. Савчина, послідовників вчення В. Вернадського).
Охарактеризовано умови, які сприяють духовному пробудженню особистості: духовний спосіб життя; пріоритет духовних цінностей; вміння керувати своїми емоціями, почуттями, думками, поведінкою; стійка самодисципліна; позитивна налаштованість особистості, установка на творчість, гармонізацію взаємостосунків зі світом; усвідомлене прагнення до духовного саморозвитку, самовдосконалення; духовно-моральний, особистісний, соціальний рівні зрілості; високий духовно-моральний і духовно-естетичний рівні розвитку; просвітлена свідомість, досягнення стану внутрішньої гармонії через молитву, медитацію та інші духовні практики.
Визначено чинники духовного пробудження особистості: класична музика, література, поезія, мистецтво, спілкування з людьми високого духовного рівня, інформаційно-енергетична взаємодія з літературою духовного спрямування тощо.
КОМП’ЮТЕРНІ ІГРИ І АУТРІЧ-ТЕХНОЛОГІЇ У ІЄРАРХІЇ КОНТЕКСТІВ НАВЧАННЯ
Authors: Чурсін М. М. , Лугова Т. А. , Сілютіна І. М. 
Published: October 2021

Розглядаються шляхи інтенсифікації процесів пізнання в умовах зростання обсягів інформації, що надходять в навчальний процес вищої школи. Звертається увага в зв'язку з цим на можливості «серйозних ігор» і аутріч-технологій, для яких навчання і пізнання виступають метою, а також контекстом, використовуючи термінологію Г.Бейтсона. У контексті навчання як «серйозні ігри», так і аутріч-технології розглядаються засобом залучення уваги суб'єкта навчання, що надзвичайно важливо, оскільки в умовах надлишку інформації найважливішим ресурсом для того, хто передає інформацію, є саме увага реципієнта. Залучення уваги споживачів інформації стає актуальною метою освітньої діяльності. У зв'язку з цим, на мікрорівні сприйняття, «людина-інформація», підкреслюються можливості комп'ютерних «серйозних ігор». Ігри такого виду, як правило, орієнтовані на професійні знання та навички – від осягнення логіки деякої діяльності до придбання автоматизму виконання окремих операцій. Вони можуть застосовуватися як для розвитку загальної здатності людини до уваги, так і для зосередження уваги на тому чи іншому об'єкті в педагогічному контексті. Вони можуть працювати і на макрорівні пізнання: рівні взаємодії того, хто пізнає, з певним колом джерел.
На макрорівні пізнання працюють і так звані аутріч-технології. У широкому сенсі аутріч – це вибудовування відносин з аудиторією поза формальних каналів спілкування, пропаганда, розширення охоплення лояльної аудиторії. Фактично аутріч-технології служать для залучення уваги потенційних споживачів інформації до існуючих інформаційних ресурсів, здійснюючи «м'який» вплив на процес пізнання.
І «серйозні ігри», і аутріч-технології знаходять своє місце в «ієрархіях контекстів» процесу пізнання, формуючи в останніх відносини, аналогічні відносинам між швидкістю і пройденою відстанню, сприяючи інтенсифікації пізнавальної діяльності.
І ті, і інші стають, таким чином, об'єктами педагогічних досліджень.
Polyprenylated Acylphloroglucinols With Different Carbon Skeletons From the Fruits of Garcinia multiflora
Authors: Teng Haida , Li Qingqing , Ma Ziyu , Li Xueni , Xie Wenli , Chen Yu , Yang Guangzhong 
Published: October 2021

Eleven new polycyclic polyprenylated acylphloroglucinols (PPAPs, 1–11) and three new monocyclic polyprenylated acylphloroglucinols (MPAPs, 12–14), together with ten known analogues were isolated from the fruits of Garcinia multiflora. These PPAPs belong to three types including the bicyclic polyprenylated acylphloroglucinols (BPAPs), the caged PPAPs, and the complicated PPAPs. Their structures and absolute configurations were determined through HRESIMS, NMR spectroscopy data, electronic circular dichroism (ECD) calculations, and gauge-independent atomic orbital (GIAO) NMR calculations with DP4+ analyses. Moreover, compounds 2 and 7 exhibited moderate cytotoxicity against three human cancer lines (MCF-7, T98, and HepG2) with IC50 values ranging from 9.81 ± 1.56 to 17.00 ± 2.75 μM.
Late Gadolinium Enhancement Cardiovascular Magnetic Resonance Assessment of Substrate for Ventricular Tachycardia With Hemodynamic Compromise
Authors: Whitaker John , Neji Radhouene , Kim Steven , Connolly Adam , Aubriot Thierry , Calvo Justo Juliá , Karim Rashed , Roney Caroline H. , Murfin Brendan , Richardson Carla , Morgan Stephen , Ismail Tevfik F. , Harrison James , de Vos Judith , Aalders Maurice C. G. , Williams Steven E. , Mukherjee Rahul , O'Neill Louisa , Chubb Henry , Tschabrunn Cory , Anter Elad , Camporota Luigi , Niederer Steven , Roujol Sébastien , Bishop Martin J. , Wright Matthew , Silberbauer John , Razavi Reza , O'Neill Mark 
Published: October 2021

Background: The majority of data regarding tissue substrate for post myocardial infarction (MI) VT has been collected during hemodynamically tolerated VT, which may be distinct from the substrate responsible for VT with hemodynamic compromise (VT-HC). This study aimed to characterize tissue at diastolic locations of VT-HC in a porcine model.Methods: Late Gadolinium Enhancement (LGE) cardiovascular magnetic resonance (CMR) imaging was performed in eight pigs with healed antero-septal infarcts. Seven pigs underwent electrophysiology study with venous arterial-extra corporeal membrane oxygenation (VA-ECMO) support. Tissue thickness, scar and heterogeneous tissue (HT) transmurality were calculated at the location of the diastolic electrograms of mapped VT-HC.Results: Diastolic locations had median scar transmurality of 33.1% and a median HT transmurality 7.6%. Diastolic activation was found within areas of non-transmural scar in 80.1% of cases. Tissue activated during the diastolic component of VT circuits was thinner than healthy tissue (median thickness: 5.5 mm vs. 8.2 mm healthy tissue, p &lt; 0.0001) and closer to HT (median distance diastolic tissue: 2.8 mm vs. 11.4 mm healthy tissue, p &lt; 0.0001). Non-scarred regions with diastolic activation were closer to steep gradients in thickness than non-scarred locations with normal EGMs (diastolic locations distance = 1.19 mm vs. 9.67 mm for non-diastolic locations, p &lt; 0.0001). Sites activated late in diastole were closest to steep gradients in tissue thickness.Conclusions: Non-transmural scar, mildly decreased tissue thickness, and steep gradients in tissue thickness represent the structural characteristics of the diastolic component of reentrant circuits in VT-HC in this porcine model and could form the basis for imaging criteria to define ablation targets in future trials.
Clinical and Pathological Characteristics of Patients With Nonproteinuric Diabetic Nephropathy
Authors: Chang Dong-Yuan , Li Meng-Rui , Yu Xiao-Juan , Wang Su-Xia , Chen Min , Zhao Ming-Hui 
Published: October 2021

IntroductionAs the most common complication of diabetes mellitus (DM), diabetic nephropathy (DN) was initially considered to begin with proteinuria preceding the progression of renal insufficiency. This clinical paradigm has been questioned in the late decades, as many DM patients without proteinuria have progressive renal insufficiency. However, the characteristics of nonproteinuric DN were not fully clear yet.Patients and MethodsA total of 390 patients with renal biopsy-proven DN in our center were retrospectively recruited in the current study. Clinical and histopathological data of the patients were analyzed. We used propensity score-matching methods to address the imbalance of age, sex, and diabetes duration for comparative analyses.ResultsAmong all the renal biopsy-proven DN patients with renal biopsy proven DN, 18 patients were classified as nonproteinuric DN. Compared with 36 propensity score-matched proteinuric DN patients, diabetic retinopathy (DR) was less frequent in nonproteinuric DN patients (38.9% vs. 66.4%, p&lt;0.05). During the follow-up of 24.0 (12.0–42.0) months, the probability of developing the end-stage renal disease (ESRD) was significantly lower in nonproteinuric DN patients than in proteinuric ones in both the propensity score-matched cohort and overall cohort (log-rank test, p&lt;0.001 and p&lt;0.001, respectively).ConclusionsCompared with proteinuric DN patients, DR was less frequent in nonproteinuric DN patients. Nonproteinuric DN patients had better renal outcomes than proteinuric DN patients.
Higher Incidence of Chronic Thromboembolic Pulmonary Hypertension After Acute Pulmonary Embolism in Asians Than in Europeans: A Meta-Analysis
Authors: Pang Wenyi , Zhang Zhu , Wang Zenghui , Zhen Kaiyuan , Zhang Meng , Zhang Yunxia , Gao Qian , Zhang Shuai , Tao Xincao , Wan Jun , Xie Wanmu , Zhai Zhenguo 
Published: October 2021

Aim: To summarize the incidence of right heart catheter diagnosed chronic thromboembolic pulmonary hypertension (CTEPH) after acute pulmonary embolism (PE) in a meta-analysis.Methods: Cohort studies reporting the incidence of CTEPH after acute PE were identified via search of Medline, Embase, China National Knowledge Infrastructure and WanFang databases.Results: Twenty-two cohort studies with 5,834 acute PE patients were included. Pooled results showed that the overall incidence of CTEPH was 2.82% (95% CI: 2.11–3.53%). Subgroup analyses showed higher incidence of CTEPH in Asians than Europeans (5.08 vs. 1.96%, p = 0.01), in retrospective cohorts than prospective cohorts (4.75 vs. 2.47%, p = 0.02), and in studies with smaller sample size than those with larger sample size (4.57 vs. 1.71%, p &lt; 0.001). Stratified analyses showed previous venous thromboembolic events and unprovoked PE were both significantly associated with increased risk of CTEPH (OR = 2.57 and 2.71, respectively; both p &lt; 0.01).Conclusions: The incidence of CTEPH after acute PE is ~3% and the incidence is higher in Asians than Europeans. Efforts should be made for the early diagnosis and treatment of CTEPH in PE patients, particularly for high-risk population.