bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Cross Talk Between ROS and NO in The Viability Declination of Cryopreserved-Pollen From Paeonia Lactiflora
Authors: Ren Ruifen , Zhang Lingling , Zhou Hao , Jiang Xueru , Liu Yan 
Published: October 2021

Abstract
Reactive oxygen species (ROS) and nitric oxide (NO), as two common active molecules, are both involved in the changes of viability after liquid nitrogen (LN) stored, but the relationship between these two molecules has not been involved in plant cryopreservation up to now. In this study, the pollen of Paeonia lactiflora 'Fen Yu Nu' with significantly decreased viability after cryopreservation as materials, by studied the effects of the two regulators on each other and their biosynthesis and scavenging indexes, to explore the interaction between ROS and NO in pollen cryopreservation and its mechanism.The results showed that: the contents of ROS and NO increased significantly with the decrease of pollen viability after cryopreservation, and regulated ROS and NO content had a significant effect on post-LN pollen viability; the changes of ROS content positively regulated the endogenous NO content, and had significant effects on the expression level of NOS-like enzyme regulation gene CSU2 and its activity; while regulated NO had a positive effect on ROS content, and significantly affected the expression of NADPH oxidase and its regulatory gene RBOHJ, and also significantly affected catalase (CAT) and the substrate related to ascorbic acid (AsA)- glutathione (GSH) antioxidant cycle system. These results indicate that there was a positive interaction between ROS and NO in the pollen cryopreservation, NOS biosynthesis pathway was one of the ROS regulated NO pathways, NADPH oxidase, CAT and AsA-GSH antioxidant cycle system were the key sites for NO regulated ROS content.
Cell Wall Fracture Mechanism in Ultrasonic Assisted Cutting of Honeycomb Materials
Authors: Yu Baohua , Yao Sufang , Wu Xin , HU Xiaoping 
Published: October 2021

Abstract
Revealing the ultrasonic cutting mechanism of honeycomb composite is important for determining the acoustic parameters of the ultrasonic system and selecting the parameters of the cutting process. Understanding more details of the stress on the cell wall from ultrasonic vibrating tool and the conditions for cell wall breakage is essential to study the machining mechanism. According to the evolution of contact state between the straight edge cutter and the honeycomb cell wall in a cycle, the cutting force acting on the cell wall is divided into three stages: transverse cutting load action, longitudinal cutting load action, and no cutting load action. The cell wall deflection and stress equations under transverse cutting load were established by applying elastic thin plate small deflection theory. The deformation and fracture characteristics of the honeycomb cell wall were analyzed by combining the analytical and the finite element model. The results showed that the ultrasonic vibration of the cutter greatly improved the stiffening effect of the cell wall and its fracture was caused by the deflection under the transverse cutting load, which exceeded the maximum allowable deformation after local stiffening. In addition, with only longitudinal cutting load, it was difficult to break the critical buckling state that leads to cell wall fracture.
“Curanderismo”: Historical Zootherapy Among Criollo Inhabitants in Rural Areas of Córdoba, Argentina
Authors: Toledo Bárbara Arias , Trillo Cecilia 
Published: October 2021

Abstract
Background Studying historical sources and comparing them with current data allows us to describe the uses and customs of past human groups, as well as to make a dynamic comparison with the current state of human-environment relations. Also, this contribution focuses on the study of zootherapeutic remedies, which have been much less addressed in ethnoscience than medicinal plant resources.This article presents a compilation and analysis of animal-based remedies included in the category of "curanderismo" in the National Folklore Survey (NFS, Argentina, 1921).MethodsThe use of 37 individuals or parts of animal species of different taxa for 66 different applications is described, analyzed and related to the current use in zootherapy. ResultsThe NFS included records of 37 animal species (7 of them domestic), animal parts or animal-derived products, with 66 different uses. Of these species, 9 (3 domestic and 6 wild) continue to be used (Clitellata, Arachnida, Insecta, Mammalia, Aves, Reptilia and Amphibia) for multiple purposes.ConclusionsThe NFS reveals a complex ethnomedical system that included local biodiversity but also elements of cultural syncretism. Paying attention to them may enrich our view of the daily life of current and past rural communities.
Association of T2DM、Serum Glucose、HbA1c With Lumbar Spine Bone Mineral Density in 40-59 years adults: A Cross Sectional Study Based on the 2011-2018 NHANES Database
Authors: Liu Bo , Liu Jingshuang , Pan Junpeng , Zong Hui , Zhao Chengliang , Wang Zhijie 
Published: October 2021

Abstract
Backgrounds:Our purpose is to discuss the relationship among the status and duration of T2DM, serum glucose, glycosylated hemoglobin(HbA1c), and lumbar spine bone mineral density (LSBMD).Methods:We selected participants whose age was 40-59 in the NHANES of 2011-2018 for a cross-sectional study. We used the multiple linear regression model to evaluate the status and duration of T2DM, serum glucose, HbA1c, and LSBMD had a linear correlation. We used the smooth curve fitting and threshold effect methods to explore the potential curvilinear relationship and inflection point, further analyzed the subgroups stratified by genders and race and completed the curve fitting.Result:Finally, 5,329 people met the standard. Finally, we found that the positively correlation between the status of T2DM and the LSBMD, however, the duration of T2DM was not associated with the LSBMD.We further used the smooth curve fitting method to explore. And then we found that blood glucose and level of HbA1c had a curvilinear relationship with the BMD of the lumbar spine in the model. The curve was U-shaped. After the saturation effect and threshold effect analysis, the inflection point was 7.77mmol/L and 5.4%, respectively. According to the further subgroup analysis, we found that the blood glucose and HbA1c of male non-Hispanic whites were positively correlated to the BMD of the lumbar spine. However, in female non-Hispanic black people and Mexican Americans, they had the relationship of a U-shaped curve with the BMD of the lumbar spine.Conclusion:The BMD of the lumbar spine of middle-aged people suffering from T2DM was significantly higher than those who do not suffer from diabetes. However, the duration of T2DM was not associated with the LSBMD.Generally speaking, blood glucose and level of HbA1c had a curvilinear relationship with the BMD of the lumbar spine. The curve was U-shaped (The inflection point was 7.77mmol/L and 5.4%, respectively). The blood glucose and HbA1c of male non-Hispanic whites were positively correlated to the BMD of the lumbar spine. However, in the female non-Hispanic black people and Mexican Americans, they had the relationship of a U-shaped curve with the BMD of the lumbar spine.
Ṣadaqa and ‘Spirituality Gene’ Expression: The Qurʾan and Advances in Epigenetics
Authors: Basuki Edi , Naqiyah Naqiyah 
Published: October 2021

Charity (ṣadaqa) is commonly given for religious reasons: Muslims donate voluntarily to earn Allah’s pleasure and receive His blessings. However, there have been changes in the way Muslims perceive charity and what significance it has in their life. Many studies have addressed this issue but failed to explore the connection between ṣadaqaand mental state. This paper was aimed to complement the existing studies by analyzing the process of the shifting interpretation of charity and its positive effects on the donors. This study used qualitative analysis of primary and secondary data. The data was processed through descriptive methods and content analysis. In particular, it focused on analyzing the religious background of the donors, including the biological processes underlying their tendency to give generously. The study concluded that the practice of giving ṣadaqa increases social, emotional, and spiritual wellbeing, depending on the level of spirituality of the donors and their intention.
Estimation of Uranium Concentration in Urine Samples of Kidneys Failure Patients in Al- Muthanna Governorate
Authors: Abed Muayad M. , Mahdi Khalid H. , AL Hamadany Weam S. 
Published: October 2021

The measurement of uranium concentration in human urine is very important in assessment of occupational and public exposure to uranium. In the present work, the fission track technique was used to decide uranium concentration in blood of Kidneys Failure Patients in Al- Muthanna Governorate. The uranium concentration values in urine samples of Kidneys Failure Patients ranged between 0.92 to 4.87 , while Healthy group results were ranged 0.91 to 1.82 . Results showed that the concentration of uranium in the URINE increases in kidney failure patients
PENGELOLAAN BUMN SEBAGAI TRANSFORMASI KEUANGAN PUBLIK MENJADI KEUANGAN PRIVAT DALAM PERSEPEKTIF HUKUM KEUANGAN NEGARA
Authors: Darmawn Agus 
Published: October 2021

Penelitian bertujuan untuk menemukan perspektif yang tepat dalam pertanggungjawaban hukum pengelolaan BUMN. Penelitian ini menggunakan pendekatan normatif. Hasil penelitian menunjukkan bahwa regulasi hukum nasional belum memberikan kejelasan regulasi dalam pengelolaan BUMN. Transformasi keuangan publik menjadi keuangan privat menjadi kunci dan garis demarkasi yang jelas untuk memahami pengelolaan BUMN dalam perspektif hukum keuangan negara, sehingga menumbuhkan kepercayaan diri yang tinggi bagi Direksi dalam mengelola BUMN dalam prinsip-prinsip Tata Kelola Perusahaan yang Baik.
Correlation of Formal Clarity and Rule of Law
Authors: Сілантьєва Е. Є. 
Published: October 2021

Comprehensive analysis of approaches to understanding the essence of the categories of “rule of law” and “formal clarity” has been carried out within the framework of the conducted research. The author in order to properly understand the category of “rule of law”, has provided the views of both international and domestic researchers, who determine its essence.
The author of the work has determined the content of the concept of the rule of law on the basis of the characteristics of the rule of law. A comprehensive analysis of the reports of the European Commission and the Venice Commission on the elements of the rule of law has been conducted. Particular attention has been also paid to the essence of the rule of law principles, which are reflected in those documents. The main requirements relating to the rule of law principle, as well as the main purpose of this principle have been provided.
The author has conducted the analysis of approaches to understanding and clarifying the essence of formal clarity provided to this category by both domestic and international researchers. The main requirements for formal clarity have been provided. The procedural requirements inherent in formal clarity have been also separately mentioned in the research.
On the basis of the conducted complex characteristic and defining the essence of the categories of “rule of law” and “formal clarity” the author has carried out the analysis of their parity. The approaches of domestic and international researchers in this regard have been provided. It has been emphasized that one of the fundamental aspects of the protection of human rights and freedoms is the formal clarity of law.
It has been noted in the conclusion that the formal clarity of law implies a set of precise, unambiguous and transparent legal requirements for both lawmaking and law-enforcement processes designed to ensure the realization of human rights, interests and freedoms, as well as protection against possible manifestations of state arbitrariness that makes it possible to avoid a number of mistakes, offenses and misunderstandings of life situations.
Administrative and Legal Principles of Prosecutor’s Office Interaction with Public Administration Entities on the Issues of Performing Assigned Functions
Authors: Прокопенко О. Ю. , Кравцов В. І. 
Published: October 2021

The problem of legal regulation of interaction between the prosecutor’s office and public administration entities on the issues of performing the assigned functions has been studied. The research is based on studying such legislative acts as the Constitution of Ukraine, Laws of Ukraine “On Central Executive Agencies”, “On the Prosecutor’s Office”, “On the Status of MPs of Ukraine”, “On Temporary Investigative and Special Commissions of the Verkhovna Rada of Ukraine” and other legislative acts and bylaws regulating the interaction of the prosecutor’s office with state authorities.
The interaction of the prosecutor’s office with public administration entities has been defined as the procedure of appeal of the prosecutor’s office to the executive authorities, which is regulated by law norms, as well as the procedure of consideration of the appeals of MPs and representatives of the executive authorities in the prosecutor’s office.
The authors have established the following main directions of the interaction between the prosecutor’s office and the state authorities: consideration of Mps inquiries by the prosecutor’s office, participation of prosecutors in the work of investigative commissions and temporary special commissions of the Verkhovna Rada of Ukraine, interaction of the prosecutor’s office with the Accounting Chamber of the Verkhovna Rada of Ukraine, prosecutors’ representation of state interests in the court by presenting lawsuits within administrative, commercial or civil proceedings, interaction of the prosecutor’s office with the judicial branch of power in the process of judicial system, coordination of law enforcement activity, informing the representative authorities about the results of the activity of the prosecutor’s office and the rule of law in the state and individual territorial community.
Improvement of legal principles of cooperation between prosecutor’s office and public administration entities can take place in such areas as bringing the provisions of the Law of Ukraine “On the Prosecutor’s Office” in line with the Constitution of Ukraine, development of a common form of request to all prosecutor’s office in regard to represent the interests in court, establishment of uniform terms for all authorities to consider their requests by the prosecutor’s office, establishment of a separate norm in the Law of Ukraine “On the Prosecutor’s Office” that would regulate the procedure and conditions of coordination of law enforcement activities of other authorities by the prosecutor’s office.
Diffusion Tensor Imaging of the Olfactory System in Older Adults With and Without Hyposmia
Authors: Felix Cynthia , Chahine Lana M. , Hengenius James , Chen Honglei , Rosso Andrea L. , Zhu Xiaonan , Cao Zichun , Rosano Caterina 
Published: October 2021

Objectives: To compare gray matter microstructural characteristics of higher-order olfactory regions among older adults with and without hyposmia.Methods: Data from the Brief Smell Identification Test (BSIT) were obtained in 1998–99 for 265 dementia-free adults from the Health, Aging, and Body Composition study (age at BSIT: 74.9 ± 2.7; 62% White; 43% male) who received 3T diffusion tensor imaging in 2006–08 [Interval of time: mean (SD): 8.01 years (0.50)], Apolipoprotein (ApoEε4) genotypes, and repeated 3MS assessments until 2011–12. Cognitive status (mild cognitive impairment, dementia, normal cognition) was adjudicated in 2011–12. Hyposmia was defined as BSIT ≤ 8. Microstructural integrity was quantified by mean diffusivity (MD) in regions of the primary olfactory cortex amygdala, orbitofrontal cortex (including olfactory cortex, gyrus rectus, the orbital parts of the superior, middle, and inferior frontal gyri, medial orbital part of the superior frontal gyrus), and hippocampus. Multivariable regression models were adjusted for total brain atrophy, demographics, cognitive status, and ApoEε4 genotype.Results: Hyposmia in 1998–99 (n = 57, 21.59%) was significantly associated with greater MD in 2006–08, specifically in the orbital part of the middle frontal gyrus, and amygdala, on the right [adjusted beta (p value): 0.414 (0.01); 0.527 (0.01); respectively].Conclusion: Older adults with higher mean diffusivity in regions important for olfaction are more likely to have hyposmia up to ten years prior. Future studies should address whether hyposmia can serve as an early biomarker of brain microstructural abnormalities for older adults with a range of cognitive functions, including those with normal cognition.
COVID-19 Era Effect on Pandemic and Post-pandemic Pediatric Telemedicine Use: A Survey of the European Academy of Pediatrics Research in Ambulatory Settings Network
Authors: Reingold Stephen M. , Hadjipanayis Adamos , van Esso Diego , del Torso Stefano , Dornbusch Hans Jürgen , de Guchtenaere Ann , Pancheva Rouzha , Mujkic Aida , Syridou Garyfallia , Valiulis Arunas , Mazur Artur , Rios Joana , Spreitzer Mateja Vintar , Mamenko Marina , D'Avino Antonio , Kubatova Gabriela , Geitmann Karin , Wyder Corrine , Altorjai Peter , Michailidou Kyriaki , Grossman Zachi 
Published: October 2021

Background: During the COVID-19 pandemic, telemedicine use has increased within community pediatrics. This trend runs counter to reluctance to adaptation of the new mode of healthcare that existed prior to the pandemic. Little is known about what we can expect after the pandemic: if physicians will opt for telemedicine modalities and if tele-pediatrics will continue to be a significant mode of community pediatric care.Objective: The goal of this study was to survey primary pediatric care providers as to their experiences and clinical decision making with telemedicine modalities prior to and during the COVID-19 pandemic, as well as their projected use after the pandemic ends.Material and methods: Using the EAPRASnet database we surveyed pediatricians throughout Europe, using a web-based questionnaire. The survey was performed during the COVID-19 pandemic (June–July 2020), assessed telemedicine use for several modalities, prior to and during the pandemic as well as predicted use after the pandemic will have resolved. Participants were also surveyed regarding clinical decision making in two hypothetical clinical scenarios managed by telemedicine.Results: A total of 710 physicians participated, 76% were pediatricians. The percentage of respondents who reported daily use for at least 50% of all encounters via telemedicine modalities increased during the pandemic: phone calls (4% prior to the pandemic to 52% during the pandemic), emails (2–9%), text messages (1–6%), social media (3–11%), cell-phone pictures/video (1–9%), and video conferencing (1–7%) (p &lt; 0.005). The predicted post-pandemic use of these modalities partially declined to 19, 4, 3, 6, 9, and 4%, respectively (p &lt; 0.005), yet demonstrating a prospectively sustained use of pictures/videos after the pandemic. Reported high likelihood of remotely treating suspected pneumonia and acute otitis media with antibiotics decreased from 8 to 16% during the pandemic to an assumed 2 and 4% after the pandemic, respectively (p &lt; 0.005).Conclusions: This study demonstrates an increased utilization of telemedicine by pediatric providers during the COVID-19 pandemic, as well as a partially sustained effect that will promote telemedicine use as part of a hybrid care provision after the pandemic will have resolved.
Identification of Cardiovascular Risk Factors in Obese Adolescents With Metabolic Syndrome
Authors: Lee Jung Won , Hong Young Mi , Kim Hae Soon 
Published: October 2021

Objective: There are studies that show different associations between metabolic syndrome (MS) and cardiovascular disease in adolescent. This study is aimed to identify probable cardio-vascular risk factors in obese adolescents with MS.Methods: Sixty-five obese adolescents with a body mass index (BMI) &gt; 95 percentile were enrolled and divided into two groups with MS or without MS. Left ventricular mass (LVM), left ventricular mass index, ejection fraction, epicardial fat thickness, visceral fat thickness (VFT) and carotid intima-media thickness were measured. Anthropometric and blood chemistry parameters were estimated. Above parameters were compared based on presence or absence of MS.Results: The prevalence of MS was 23.1% in obese adolescents. LVM showed significant correlation with body mass index (BMI), hip circumference (HC), fat mass, total cholesterol (TC), LDL-cholesterol (LDL-C) and waist circumference (WC). VFT significantly correlated with WC, BMI, hip circumflex (HC), obesity index (OI), fat %, fat mass, insulin, TC, LDL-C, insulin, triglyceride (TG), glucose, homeostatic model assessment for insulin resistance (HOMA-IR) and leptin.Conclusions: Screening for the MS in overweight adolescents may help to predict risk of future cardiovascular disease. These data suggest that LVMI and VFT are significant parameters for predicting cardiovascular disease risk in obese adolescents.