bluuebunny/crossref_metadata_2025_split huggingface dataset:
How do cyber- and traditional workplace bullying, organizational justice and social support, affect psychological distress among civil servants?
Authors: Desrumaux Pascale , Hellemans Catherine , Malola Pascal , Jeoffrion Christine 
Published: September 2021

Le harcèlement moral au travail concentre une synergie d’agissements et de techniques nocives visant à isoler, humilier, maltraiter ou terroriser psychologiquement des personnes au travail (Desrumaux, 2011 ; Einarsen et al., 2011). Le cyber-harcèlement a les mêmes objectifs mais recourt à des technologies et des dispositifs de communication digitaux. Ces deux types de harcèlements ont des conséquences destructrices sur la personne et affectent sa santé mentale générant de la détresse. Or certaines ressources telles que la justice organisationnelle (Colquitt, 2001) et les soutiens perçus (Desrumaux et al., 2018) sont susceptibles de préserver la personne de la détresse. Cette étude examine les effets du harcèlement moral au travail traditionnel et du cyber harcèlement au travail, de la justice organisationnelle et du soutien social sur la détresse psychologique. À l’aide d’un devis transversal, nous avons soumis un questionnaire en ligne à 179 fonctionnaires français. Basées sur la méthode de Hayes et Preacher (2014), les analyses ont indiqué que la justice organisationnelle, et, spécifiquement, la justice interpersonnelle, étaient des médiateurs partiels de la relation entre le harcèlement traditionnel et la détresse psychologique. Le soutien du superviseur était un médiateur partiel de la relation entre le harcèlement traditionnel et la détresse psychologique, et un médiateur total de la relation entre le cyber-harcèlement et la détresse psychologique. Au niveau des implications, l’effet indirect du soutien du superviseur entre les formes traditionnelles et digitales de harcèlement et la détresse psychologique montre le rôle majeur de la hiérarchie dans la prévention des effets du harcèlement. Enfin, la justice organisationnelle en tant que médiateur constitue une voie intéressante, suggérant qu’il est essentiel de prévenir les conséquences néfastes du harcèlement traditionnel et du cyber harcèlement En particulier, l’étude indique le rôle majeur de la justice interpersonnelle entre le harcèlement et la détresse. La prévention devra insister sur l’importance de développer des valeurs de compréhension et de considération dans l’entreprise. La communication, les relations respectueuses et, par-dessus tout, le soutien des superviseurs sont des solutions essentielles à mettre en place pour diminuer la détresse psychologique au travail.
Du salon à la scène : l’ascension des femmes et du piano au Brésil du vingtième siècle
Authors: Vasconcellos de Carvalho Dalila 
Published: September 2021

Dans cet article, nous analysons comment Guiomar Novaes (1894-1979), Antonietta Rudge (1885-1974) et Magda Tagliaferro (1893-1986) sont devenues les premières concertistes du Brésil et les raisons pour lesquelles des femmes, plutôt que des hommes, furent les premières à atteindre ce statut dans un contexte marqué par deux normes sociales de la fin du dix-neuvième siècle qui rendaient presque impossible une telle carrière : les restrictions de genre, confinant les femmes à pratiquer le piano de façon dilettante, et l’émergence tardive de récitals de piano. Nous pouvons mieux comprendre leur ascension en considérant de façon parallèle les trajectoires d’autres pianistes comme Ernesto Nazareth (1863-1934), Luiza Leonardo (1859-1934), Chiquinha Gonzaga (1847-1935) et Souza Lima (1898-1982).
Effects of Foliar and Soil-Applied Liquid Organic Fertilizers on the Growth of <em>Basella alba</em> L. and <em>Centella asiatica</em> L.
Authors: Ranasinghe R. H. A. A. , Ratnayake R. M. C. S. , Kannangara B. T. S. D. P. 
Published: September 2021

Purpose: Environmental-friendly organic fertilizers reduce the adverse impacts of chemical fertilizers. This study was conducted to formulate organic liquid fertilizers using selected plant materials i.e., Tithonia diversifolia, Mikania scandens, Chromolaena odorata and Gliricidia sepium with selected organic wastes to compare the efficacies of foliar and soil-applications over the growth of leafy vegetables; Basella alba and Centella asiatica. Research Method: Selected plant materials were allowed to decompose for two months and thereafter fish waste was hydrolyzed separately with fruit wastes of Carica papaya, Ananas comosus and (1:1 w/w) mixture of both were mixed and nutrients analyzed. Fertilizers were foliar and soil-applied separately on C. asiatica and B. alba in RCBD in pot trials. Findings: Fertilizer formulated with decomposed plants + fish waste hydrolyzed with C. papaya significantly recorded the highest N (0.57%), P (0.06%) and highest growth of C. asiatica and B. alba over both soil and foliar applications followed by the fertilizer formulated with decomposed plants + fish waste hydrolyzed with C. papaya + A. comosus. Foliar-application of B. alba significantly showed the highest growth than the soil-application [shoot height (36.6±3.4 cm vs 30.0±1.5 cm), number of leaves per plant (21.7±1.4 vs 17.5±0.8) and plant fresh-weight (61.5±1.8 vs 55.6±0.9 g)] whereas, C. asiatica indicated no significant difference considering both fertilizer application methods. Research limitation: Pot experiments were carried out to provide uniform soil conditions for the experiment which was the main limitation compared to field trials. Originality/value: The formulated novel fertilizers could be utilized effectively in organic farming for safe and healthy leafy vegetables which reduce the adverse impacts of chemical fertilizers.
Effect of Partial Replacement of Corn with Breadfruit (<em>Artocarpus altilis</em>) Flour on Growth Performance and Meat Quality of Broiler Chickens
Authors: Dayarathna Pradeep Kumara , Jayarathna Gayathree Nidarshika , Nawarathne Shan Randima , Jayasena Dinesh Darshaka , Dissanayake Sumudu Priyadarshani , Heo Jung Min , Nambapana Maleeka Nadeemale 
Published: September 2021

Purpose: There is a need to explore the use of non-conventional, locally available and cheap energy-rich ingredients to substitute corn in broiler diets as it is used mainly for human consumption in developing countries. Therefore, this study investigated the effect of partial substitution of corn with breadfruit flour (BFF) in broiler diets on growth performances and meat quality in broiler chickens. Research Method: One hundred and eighty day-old straight-run “Cobb 500” broiler chicks (45.92 ± 0.43 g) were randomly allocated into one of three dietary treatments (Corn based basal diet with no BFF [Control], Corn-substituted basal diet with 5% BFF [BFF5], and Corn-substituted basal diet with 10% BFF [BFF10]) with six replications and 10 birds per replicate. Growth parameters including body weights, average daily gain, average daily feed intake, feed conversion ratio, and organ weights and meat quality parameters were determined. Findings: The broilers fed BFF10 significantly (P < 0.05) improved the body weight, average daily weight gain, and feed efficiency of broilers for the complete experimental period (d 1-35). Further, the same diet improved (P < 0.05) the average daily feed intake of broilers for the starter period (d 1-7) compared to the control diet. Furthermore, broilers fed BFF10 had a heavier (P < 0.05) heart, liver and empty intestine than those fed BFF5. Moreover, breast meat of broilers fed BFF10 had a significant (P < 0.05) lower crude fat content and CIE a* value than that of broilers fed other diets. Originality/value: Breadfruit flour would be a suitable non-conventional energy feed source to partly substitute corn in broiler diets up to 10% with improved growth performance and meat quality in broiler chickens.
Severity of Associated Weeds in Rabi Crops and their Control Measures Perceived by Farmers
Authors: Islam S. M. A. , Rana M. A. I. , Ahmed M. , Islam M. M. 
Published: September 2021

Purpose: The study was conducted to identify the associated weeds of Rabi (winter) crops and their control measures used by the farmers at Dumuria and Batiaghata upazila in Khulna district of Bangladesh. Research Method: Data were collected from purposively selected 73 respondents using structured interview conducted from 4 January to 20 April, 2019. Findings: In the study area, Echinochloa crussgalli and Cynodon dactylon were found as dominant within rice fields with the highest severity index of 25.34% and 20.54% respectively. In sesame fields, Cucumis melo var. agrestis and Cynodon dactylon were found with 16.78% and 12.33% severity index respectively. The severity index of Cynodon dactylon was the highest in majority of the vegetable crops. The weeding of rice, potato, bitter gourd, spinach, country bean was done within the critical weeding regime but in the rest of the crops weeding was not done during the critical weeding regime. Originality/value: Farmers spend about 40% of the total production cost on weed control and the critical weeding regime has a major impact on effectiveness of weed control, overall economic benefit and net income.
Consumers' Willingness to Pay for Organic Fresh Milk in Saudi Arabia
Authors: Almarri Amal , Al-Mahish Mohammed 
Published: September 2021

Purpose: Consumption of organic food among consumers in Saudi Arabia has increased in recent times due to increased awareness of health benefits of organic food. The purpose of this paper is to estimate the average amount a consumer is willing to pay in Saudi Arabia for fresh organic milk. Research Method: This paper used the Double Bounded Dichotomous Choice (DBDC) model to identify key determinants of consumers’ willingness to pay (WTP) for fresh organic milk. Findings: The results showed that organic product label, consumers’ awareness about nutritional benefits of organic milk, agility, and income were key determinants of consumers’ WTP for fresh organic milk. The paper estimated average consumers’ willingness to pay for one litre of fresh organic milk to be SAR 14 while the nonparametric estimates of WTP ranged in values from as low as SAR 10 to as high as 12 SAR. Originality/value: The results are important to the domestic dairy companies and existing European organic long-life milk exporters to Saudi Arabia to initiate business ventures on organic fresh milk business.
Integrin CD11b Negatively Regulates B Cell Receptor Signaling to Shape Humoral Response during Immunization and Autoimmunity
Authors: Zhou Mingqian , Dascani Paul , Ding Chuanlin , Kos Justin T , Tieri David , Lin Xiaoying , Caster Dawn , Powell David , Wen Chengping , Watson Corey T , Yan Jun 
Published: September 2021

Abstract
Our previous work has revealed the ability of CD11b to regulate BCR signaling and control autoimmune disease in mice. However, how CD11b regulates the immune response under normal conditions remains unknown. Through the use of a CD11b knockout model on a nonautoimmune background, we demonstrated that CD11b-deficient mice have an elevated Ag-specific humoral response on immunization. Deletion of CD11b resulted in elevated low-affinity and high-affinity IgG Ab and increases in Ag-specific germinal center B cells and plasma cells (PCs). Examination of BCR signaling in CD11b-deficient mice revealed defects in association of negative regulators pLyn and CD22 with the BCR, but increases in colocalizations between positive regulator pSyk and BCR after stimulation. Using a CD11b-reporter mouse model, we identified multiple novel CD11b-expressing B cell subsets that are dynamically altered during immunization. Subsequent experiments using a cell-specific CD11b deletion model revealed this effect to be B cell intrinsic and not altered by myeloid cell CD11b expression. Importantly, CD11b expression on PCs also impacts on BCR repertoire selection and diversity in autoimmunity. These studies describe a novel role for CD11b in regulation of the healthy humoral response and autoimmunity, and reveal previously unknown populations of CD11b-expressing B cell subsets, suggesting a complex function for CD11b in B cells during development and activation.
An IRF4–MYC–mTORC1 Integrated Pathway Controls Cell Growth and the Proliferative Capacity of Activated B Cells during B Cell Differentiation In Vivo
Authors: Patterson Dillon G , Kania Anna K , Price Madeline J , Rose James R , Scharer Christopher D , Boss Jeremy M 
Published: September 2021

Abstract
Cell division is an essential component of B cell differentiation to Ab-secreting plasma cells, with critical reprogramming occurring during the initial stages of B cell activation. However, a complete understanding of the factors that coordinate early reprogramming events in vivo remain to be determined. In this study, we examined the initial reprogramming by IRF4 in activated B cells using an adoptive transfer system and mice with a B cell–specific deletion of IRF4. IRF4-deficient B cells responding to influenza, 4-hydroxy-3-nitrophenylacetyl–Ficoll, and LPS divided but stalled during the proliferative response. Gene expression profiling of IRF4-deficient B cells at discrete divisions revealed IRF4 was critical for inducing MYC target genes, oxidative phosphorylation, and glycolysis. Moreover, IRF4-deficient B cells maintained an inflammatory gene expression signature. Complementary chromatin accessibility analyses established a hierarchy of IRF4 activity and identified networks of dysregulated transcription factor families in IRF4-deficient B cells, including E-box binding bHLH family members. Indeed, B cells lacking IRF4 failed to fully induce Myc after stimulation and displayed aberrant cell cycle distribution. Furthermore, IRF4-deficient B cells showed reduced mTORC1 activity and failed to initiate the B cell activation unfolded protein response and grow in cell size. Myc overexpression in IRF4-deficient cells was sufficient to overcome the cell growth defect. Together, these data reveal an IRF4–MYC–mTORC1 relationship critical for controlling cell growth and the proliferative response during B cell differentiation.
The cricothyroid versus the spray-as-you-go method for topical anesthesia during flexible bronchoscopy
Authors: Madan Karan , Iyer Hariharan , Arunachalam M , Mittal Saurabh , Tiwari Pawan , Hadda Vijay , Mohan Anant , Guleria Randeep 
Published: September 2021

Background:
Lignocaine can be administered during bronchoscopy using either a direct injection through the cricothyroid membrane (the cricothyroid method) or a spray of lignocaine solution through the bronchoscope working channel (the spray-as-you-go method). In this meta-analysis of randomized controlled trials (RCTs), we compared the efficacy of these two methods for topical anesthesia during flexible bronchoscopy.

Methods:
We performed a systematic search to extract the relevant RCTs comparing the two techniques.

Results:
Five RCTs meeting the inclusion criteria (747 subjects) were identified. The cricothyroid method was associated with significantly less cough (standardized mean difference [SMD] = −1.18, 95% confidence interval [CI] [−1.75, −0.62], P < 0.001, significant heterogeneity I2 = 86%, P < 0.001). On analysis of secondary outcomes, the cricothyroid method was associated with a greater operator-rated procedure satisfaction (SMD = 1.00, 95% CI [0.74, 1.25], P < 0.001), less time for upper airway negotiation (mean difference, MD = −0.99, 95% CI [−1.37, −0.6], P < 0.001), and a significantly less cumulative dose of lignocaine administered (MD = −68.12, 95% CI [−130.18, −6.06], P = 0.03). The overall procedure duration (MD = 0.08, 95% CI [−0.09, 0.24], P = 0.36) and patient discomfort (MD = −0.08, 95% CI [−0.38, 0.22], P = 0.59) were not different between the two methods. There was no significant publication bias (P = 0.94).

Conclusions:
The cricothyroid method is associated with less cough during flexible bronchoscopy. Other advantages are a greater operator-rated procedure satisfaction at a less cumulative lignocaine dose. These findings highlight the superior performance characteristics of the cricothyroid method for lignocaine administration for flexible bronchoscopy.
High proportion of drug-resistant isolates in adult community-acquired pneumonia from Northeast India
Authors: Kalita Deepjyoti , Sarma Ridip Kumar , Sharma Kripesh Ranjan , Deka Sangeeta 
Published: September 2021

Background:
Empirical antibiotic therapy is the mainstay of management of adult community-acquired pneumonia (CAP) globally. Knowledge of prevalent pathogen (bacterial) profile and drug susceptibility pattern is very essential for appropriate management of CAP cases, which again calls for regular update of pathogen profile in a given locality. This study was to identify the bacterial etiology of CAP cases and their antibiotic susceptibility pattern.

Methods:
This cross-sectional study was done on adult CAP patients from medicine, respiratory medicine, and intensive care unit area in our tertiary care hospital between May 1, 2015, and October 30, 2016. Subjects were enrolled continuously, and expectorated sputum, bronchoalveolar lavage fluid, and blood culture were performed. Urine antigen test was done for Streptococcus
pneumoniae and Legionella pneumophila. Three types of ELISA (IgM, IgG, and IgA) were performed for atypical agents (Mycoplasma, Chlamydia, and Legionella) of CAP. Isolates obtained from culture of Sputum/BAL/Blood were further processed for antibiotic susceptibility testing - by disc diffusion as well as E-test method (latter for MIC i.e. minimum inhibitory concentration, determination).

Results:
About 574 subjects were included, and in 266 (46.3%) cases, bacterial pathogen could be detected. Klebsiella
pneumoniae (33.6%) and S. pneumoniae (32.9%) were the predominant agents identified. Atypical agents (Mycoplasma, Legionella, and Chlamydia) were at 15.1%. A high proportion of pneumococci isolates were multidrug resistant (52.6%). Resistance to beta-lactams, macrolide, and other agents was on the higher side, but fluoroquinolones were found to be less resistant (15.8%–21.1%). Extended-spectrum beta-lactamase (among Klebsiella isolates) and methicillin-resistant Staphylococcus aureus were also detected.

Conclusion:
A moderate-to-high degree of drug-resistant in adult CAP was evident, which is detrimental in effective empirical management of such cases. Urgent implementation of antibiotic stewardship scheme is the need of the hour.
A comparative study of the efficacy of Glidescope versus Macintosh direct laryngoscopy for intubation in pediatric patients undergoing cardiac surgery
Authors: Zabani Ibrahim , AlHarbi Mohammed , AlHassoun Abdulkarim , Iqbal Shafat , Al Amoudi Dareen , AlOtaibi Sultan , Saad Hasan 
Published: September 2021

Background:
The Glidescope is a novel, portable, reusable video laryngoscope that has provided superior laryngeal visualization to facilitate tracheal intubation, especially in the management of difficult airways. In this study, we aimed to compare the efficacy of the Glidescope (video-laryngoscope) against the Macintosh direct laryngoscope.

Methods:
Fifty patients were randomly selected via simple randomization using computer-generated random numbers, and sorted into two groups of 25 patients: the Glidescope group and the Macintosh group. We included pediatric patients undergoing cardiac surgery for the repair of congenital heart disease. Those with suspected difficult intubation, preterm babies with low body weight, and patients at risk of aspiration were all excluded.

Results:
Patients’ baseline demographic and clinical characteristics were found to be comparable in the two groups. The mean intubation time was 24.1 ± 13.6 s in the Glidescope group, as compared to 18.1 ± 5.9 s in the Macintosh group. Blade insertion was easy in 92% and 96% of the patients in the Glidescope and Macintosh groups, respectively. Tracheal intubation was considered easy in 84% of the Glidescope group, compared to 92% of the Macintosh group. There was a statistically significant correlation between the ease of tracheal intubation and the used intubation method (rho = –0.35; P = 0.014).

Conclusion:
Our findings indicate that the Glidescope can be used as an efficient modality for obtaining successful intubations with no complications. Ease of tracheal intubation was the only outcome that was found to be affected by the used modality. Further investigations with proper sample sizes are needed.
Management and outcomes of patients on maintenance dialysis during the first and second wave of the COVID-19 pandemic in Geneva, Switzerland
Authors: Zamberg Ido , Mavrakanas Thomas , Ernandez Thomas , Bourquin Vincent , Zellweger Michael , Marangon Nicolas , Raimbault Françoise , Winzeler Rebecca , Iten Anne , Hammer Nathalie , Ponte Belen , Carballo Sebastian , Martin Pierre-Yves , Saudan Patrick 
Published: September 2021

BACKGROUND: Patients on maintenance dialysis are at high risk for serious complications from COVID-19 infection, including death. We present an overview of local experience with dialysis unit management and reorganisation, local epidemiology and outcomes during the COVID-19 outbreak in Geneva, Switzerland, where SARS-CoV-2 incidence was one of the highest in Europe.
METHODS: All SARS-CoV-2-positive outpatients on maintenance dialysis were transferred from their usual dialysis facility to the Geneva University Hospitals dialysis unit to avoid creation of new clusters of transmission. Within this unit, appropriate mitigation measures were enforced, as suggested by the institutional team for prevention and control of infectious diseases.
RESULTS: From 25 February to 31 December 2020, 82 of 279 patients on maintenance dialysis tested positive for SARS-CoV-2 during two distinct waves, with an incidence rate of 73 cases per 100,000 person-days during the first wave and 342 cases per 100,000 during the second wave, approximately four- to six-fold higher than the general population. The majority of infections (55%) during both waves were traced to clusters. Most infections (62%) occurred in men. Sixteen patients (34%) died from COVID-19 related complications. Deceased patients were older and had a lower body mass index as compared with patients who survived the infection.
CONCLUSION: SARS-CoV-2 is associated with high infection and fatality rates in the dialysis population. Strict mitigation measures seemed to be effective in controlling infection spread among patients on maintenance dialysis outside of clusters. Large scale epidemiological studies are needed to assess the efficacy of preventive measures in decreasing infection and mortality rates within the dialysis population.
CAPACITAÇÃO DO PROFESSOR E O DESAFIO DA EDUCAÇÃO INCLUSIVA
Authors: Alves dos Santos Aldirene 
Published: September 2021

Este artigo apresenta resultado de uma pesquisa realizada a partir de uma abordagem qualitativa cujo eixo de discussão foi à capacitação do professor e o desafio diante da educação inclusiva. Teve como problema: Até que ponto os professores do ano de 2013 das séries iniciais do ensino fundamental da Escola x, encontram-se capacitado para desenvolver atividades docentes em uma perspectiva inclusiva? Tinha -se como hipótese que os professores das escolas de Urucuia não foram preparados para vivenciar a educação inclusiva na formação inicial. O objetivo era, compreender se os professores das séries iniciais do ensino fundamental da Escola x encontram-se capacitado para desenvolver atividades docentes em uma perspectiva inclusiva. Foram feitas uma pesquisa bibliográfica e uma pesquisa de campo, sendo que, para a coleta de dados o instrumento utilizado foi a entrevista estruturada com professores da séries iniciais do ensino fundamental. A pesquisa bibliográfica fundamentou em autores como Glat e Fernandes (2011), Barros (2013), Sánchez (2005), Beyer (2006), Mazzotta (2002), A conclusão foi que o corpo docente em questão não encontra-se capacitado ou seja, precisa de uma formação continuada, pois percebe-se que os professores têm conhecimento sobre o tema, mas de forma generalizada e não no contexto escolar.