bluuebunny/crossref_metadata_2025_split huggingface dataset:
Concepts in Action: Introduction
Authors: Bechberger Lucas , Liu Mingya 
Published: August 2021

AbstractIt is impossible to talk about human cognition without talking about concepts—there simply is no human cognition without concepts. Concepts form an abstraction of reality that is central to the functioning of the human mind. Conceptual knowledge (of e.g., APPLE, LOVE and BEFORE) is crucial for us to categorize, understand, and reason about the world. Only equipped with concepts and words for them can we successfully communicate and carry out actions. But what exactly are concepts? How are concepts acquired? How does the human mind use concepts? In this introduction chapter, we elaborate on these questions (i.e., representation, learning, application), and provide summaries of the seven individual chapters in the volume, which from different scientific disciplines relate to one or the other of the questions.
Generalizing Psychological Similarity Spaces to Unseen Stimuli
Authors: Bechberger Lucas , Kühnberger Kai-Uwe 
Published: August 2021

AbstractThe cognitive framework of conceptual spaces proposes to represent concepts as regions in psychological similarity spaces. These similarity spaces are typically obtained through multidimensional scaling (MDS), which converts human dissimilarity ratings for a fixed set of stimuli into a spatial representation. One can distinguish metric MDS (which assumes that the dissimilarity ratings are interval or ratio scaled) from nonmetric MDS (which only assumes an ordinal scale). In our first study, we show that despite its additional assumptions, metric MDS does not necessarily yield better solutions than nonmetric MDS. In this chapter, we furthermore propose to learn a mapping from raw stimuli into the similarity space using artificial neural networks (ANNs) in order to generalize the similarity space to unseen inputs. In our second study, we show that a linear regression from the activation vectors of a convolutional ANN to similarity spaces obtained by MDS can be successful and that the results are sensitive to the number of dimensions of the similarity space.
Does the Activation of Motor Information Affect Semantic Processing?
Authors: Scerrati Elisa , Iani Cristina , Rubichi Sandro 
Published: August 2021

AbstractSeveral behavioral studies show that semantic content influences reach-to-grasp movement responses. However, not much is known about the influence of motor activation on semantic processing. The present study aimed at filling this gap by examining the influence of pre-activated motor information on a subsequent lexical decision task. Participants were instructed to observe a prime object (e.g., the image of a frying pan) and then judge whether the following target was a known word in the lexicon or not. They were required to make a keypress response to target words describing properties either relevant (e.g., handle) or irrelevant (e.g., ceramic) for action or unrelated to the prime object (e.g., eyelash). Response key could be located on the same side as the depicted action-relevant property of the prime object (i.e., spatially compatible key) or on the opposite side (i.e., spatially incompatible key). Results showed a facilitation in terms of lower percentage errors when the target word was action-relevant (e.g., handle) and there was spatial compatibility between the orientation of the action-relevant component of the prime object and the response. This preliminary finding suggests that the activation of motor information may affect semantic processing. We discuss implications of these results for current theories of action knowledge representation.
Localization and duality for ABJM latitude Wilson loops
Authors: Griguolo Luca , Guerrini Luigi , Yaakov Itamar 
Published: August 2021

Abstract
We investigate several aspects of BPS latitude Wilson loops in gauge theories in three dimensions with $$ \mathcal{N} $$
N
≥ 4 supersymmetry. We derive a matrix model for the bosonic latitude Wilson loop in ABJM using supersymmetric localization, and show how to extend the computation to more general Chern-Simons-matter theories. We then define latitude type Wilson and vortex loop operators in theories without Chern-Simons terms, and explore a connection to the recently derived superalgebra defining local Higgs and Coulomb branch operators in these theories. Finally, we identify a BPS loop operator dual to the bosonic latitude Wilson loop which is a novel bound state of Wilson and vortex loops, defined using a worldvolume supersymmetric quantum mechanics.
Treatment of closed femoral shaft fractures in children aged 2–10 years: a systematic review and meta-analysis
Authors: van Cruchten Stijn , Warmerdam Eefke C. , Kempink Dagmar R. J. , de Ridder Victor A. 
Published: August 2021

Abstract
Objective
To review current literature on treatment of closed femoral shaft fractures in children of 2–10 years old, with subgroup analysis of children aged 2–6 years, comparing intramedullary nailing (IMN) to conservative treatment modalities.

Methods
We included clinical trials and observational studies that compared traction and subsequent casting (TSC), spica casting and IMN for treatment of femur shaft fractures in children of 2–10 years of age. Subgroup analysis of children aged 2–6 years was performed.

Results
Compared to treatment with immediate spica casting, IMN led to significantly less coronal angulation (mean difference (MD): 2.03 degrees, confidence interval (CI) 1.15–2.90), less sagittal angulation (MD: 1.59 degrees, CI 0.82–2.35) and lower rates of LLD (Risk difference (RD): 0.07, CI 0.03–0.11). In terms of rehabilitation, IMN leaded to shorter time until walking with aids (MD: 31.53 days, CI 16.02–47.03), shorter time until independent ambulation (MD: 26.59 days, CI 22.07, 31.11) and shorter time until full weight bearing (MD: 27.05 days, CI 6.11, 47,99). Compared to TSC, IMN led to a lower rate of malunion (RD: 0.31, CI 0.05–0.56), shorter hospital stays (MD: 12.48 days, CI 11.57, 13.39), time until walking with aids (MD: 54.55, CI 40.05–69.04) and full weight bearing (MD: 27.05 days [6.11, 47,99]).

Conclusion
Although a lack of quality evidence, this systematic review showed a clear tendency to treatment with elastic intramedullary nails of femoral shaft fractures in children of 2–10 years of age.

Level of evidence
3.
Biodegradation of metoprolol in oxic and anoxic hyporheic zone sediments: unexpected effects on microbial communities
Authors: Rutere Cyrus , Posselt Malte , Ho Adrian , Horn Marcus A. 
Published: August 2021

Abstract
Metoprolol is widely used as a beta-blocker and considered an emerging contaminant of environmental concern due to pseudo persistence in wastewater effluents that poses a potential ecotoxicological threat to aquatic ecosystems. Microbial removal of metoprolol in the redox-delineated hyporheic zone (HZ) was investigated using streambed sediments supplemented with 15 or 150 μM metoprolol in a laboratory microcosm incubation under oxic and anoxic conditions. Metoprolol disappeared from the aqueous phase under oxic and anoxic conditions within 65 and 72 days, respectively. Metoprolol was refed twice after initial depletion resulting in accelerated disappearance under both conditions. Metoprolol disappearance was marginal in sterile control microcosms with autoclaved sediment. Metoprolol was transformed mainly to metoprolol acid in oxic microcosms, while metoprolol acid and α-hydroxymetoprolol were formed in anoxic microcosms. Transformation products were transient and disappeared within 30 days under both conditions. Effects of metoprolol on the HZ bacterial community were evaluated using DNA- and RNA-based time-resolved amplicon Illumina MiSeq sequencing targeting the 16S rRNA gene and 16S rRNA, respectively, and were prominent on 16S rRNA rather than 16S rRNA gene level suggesting moderate metoprolol-induced activity-level changes. A positive impact of metoprolol on Sphingomonadaceae and Enterobacteriaceae under oxic and anoxic conditions, respectively, was observed. Nitrifiers were impaired by metoprolol under oxic and anoxic conditions. Collectively, our findings revealed high metoprolol biodegradation potentials in the hyporheic zone under contrasting redox conditions associated with changes in the active microbial communities, thus contributing to the attenuation of micropollutants.

Key points
• High biotic oxic and anoxic metoprolol degradation potentials in the hyporheic zone.
• Key metoprolol-associated taxa included Sphingomonadaceae, Enterobacteraceae, and Promicromonosporaceae.
• Negative impact of metoprolol on nitrifiers.
Combining Calcium Hydroxylapatite and Hyaluronic Acid Fillers for Aesthetic Indications: Efficacy of an Innovative Hybrid Filler
Authors: Fakih-Gomez Nabil , Kadouch Jonathan 
Published: August 2021

Abstract
Background
Limited data are available describing effectiveness of combining the use of calcium hydroxylapatite (CaHA) and hyaluronic acid (HA).

Methods
The authors performed a retrospective chart review of patients injected with a premixed combination of CaHA and a cohesive polydensified matrix (CPM®) HA (CaHA:CPM-HA ) in the authors’ aesthetic practices. The midface and lower face were injected. Patients’ records were evaluated, and treatment results were scored using the Merz Aesthetics Scale for the jawline® (clinician rated, CR-MASJ). Adverse events were recorded.

Results
A total of 41 patients were included, all females with a mean age of 47.5 years (range 21–63 years). The mean CR-MASJ score improved from 2.12 at baseline to 0.68 at t = 3 months (SD = 0.69, 95% CI 1.28–1.60) and 1.27 at t = 12 months (SD = 0.74, 95% CI 0.43–0.74). 100% of the subjects had experienced a ≥1-point improvement in CR-MASJ score at t = 3 months, versus 85% at t = 12 months. No adverse events were reported.

Conclusion
The results of this study support the volumizing and lifting potential of the hybrid mix CaHA:CPM-HA for treatment of cheeks and jawline.

Level of Evidence IV
This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.
Dynamic mode decomposition in adaptive mesh refinement and coarsening simulations
Authors: Barros Gabriel F. , Grave Malú , Viguerie Alex , Reali Alessandro , Coutinho Alvaro L. G. A. 
Published: August 2021

AbstractDynamic mode decomposition (DMD) is a powerful data-driven method used to extract spatio-temporal coherent structures that dictate a given dynamical system. The method consists of stacking collected temporal snapshots into a matrix and mapping the nonlinear dynamics using a linear operator. The classical procedure considers that snapshots possess the same dimensionality for all the observable data. However, this often does not occur in numerical simulations with adaptive mesh refinement/coarsening schemes (AMR/C). This paper proposes a strategy to enable DMD to extract features from observations with different mesh topologies and dimensions, such as those found in AMR/C simulations. For this purpose, the adaptive snapshots are projected onto the same reference function space, enabling the use of snapshot-based methods such as DMD. The present strategy is applied to challenging AMR/C simulations: a continuous diffusion–reaction epidemiological model for COVID-19, a density-driven gravity current simulation, and a bubble rising problem. We also evaluate the DMD efficiency to reconstruct the dynamics and some relevant quantities of interest. In particular, for the SEIRD model and the bubble rising problem, we evaluate DMD’s ability to extrapolate in time (short-time future estimates).
Diet quality indices and gastrointestinal cancer risk: results from the Lifelines study
Authors: Moazzen Sara , Cortes-Ibañez Francisco O. , van der Vegt Bert , Alizadeh Behrooz Z. , de Bock Geertruida H. 
Published: August 2021

Abstract
Objective
To investigate the long-term association between four dietary quality indices and the risk of gastrointestinal (GI) cancer.

Methods
Baseline details of the dietary intake of participants, assessed by a single food frequency questionnaire from the prospective Lifelines population-based cohort were translated to diet quality scores using several dietary and dietary-lifestyle indices. Incident cases of GI cancer were then assessed by linkage to the Dutch nationwide histo-cytopathology registry. The association between GI cancer risk and diet quality (defined as higher quintiles on dietary indices compared to the first quintile) was assessed by multivariable Cox proportional hazard models.

Results
We included 72,695 participants aged 51.20 ± 8.71 years with a median follow-up to cancer diagnosis of 8 years (interquartile range 2 years). During follow-up, 434 colorectal cancers and 139 upper GI cancers were diagnosed. There was a significant reduction in colorectal cancer risk for high categories in the American Cancer Society (ACS) Index (hazard ratio 0.62; 95% CI 0.46–0.84). However, high dietary index scores were not associated with strong beneficial effects on upper GI cancer risk.

Conclusion
High quintiles on the ACS Index were associated with a significantly reduced risk of colorectal cancer. This index may be of use in a colorectal cancer prevention program.
Tolerable amounts of amino acids for human supplementation: summary and lessons from published peer-reviewed studies
Authors: Blachier François , Blais Anne , Elango Rajavel , Saito Kuniaki , Shimomura Yoshiharu , Kadowaki Motoni , Matsumoto Hideki 
Published: August 2021

AbstractAmino acid supplementation may be indicated to correct for insufficient amino acid intake in healthy individuals, and in specific physiological or pathophysiological situations. However, there is a concern to not supplement beyond the tolerable upper intake level (UL) by determining parameters of no-observed-adverse-effect level (NOAEL) or lowest-observed-adverse-effect level (LOAEL) for each amino acid. Since the NOAEL and LOAEL values are at least one order of magnitude different when comparing the values obtained in rats and humans, the aim of this review is to evaluate to what extent the amino acid UL measured in the rat model, when referenced to the dietary usual consumption (UC) and dietary requirement (RQ) for indispensable amino acids, may be used as an approximation of the UL in humans. This review then compares the ratios of the NOAEL or LOAEL over UC and RQ in the rat model with the same ratios calculated in humans for the nine amino acids (arginine, serine, glycine, histidine, leucine, lysine, methionine, phenylalanine, and tryptophan) for which this comparison can be done. From the calculations made, it appears that for these 9 amino acids, the calculated ratios for rats and humans, although rather different for several amino acids, remains for all of them in the same order of magnitude. For tryptophan, tyrosine, and valine, the ratios calculated in rats are markedly different according to the sex of animals, raising the view that it may be also the case in humans.
Anthropogenic Transformation Disconnects a Lowland River From Contemporary Carbon Stores in Its Catchment
Authors: Tittel Jörg , Musolff Andreas , Rinke Karsten , Büttner Olaf 
Published: August 2021

AbstractRivers transport carbon from continents to oceans. Surprisingly, this carbon has often been found to be centuries old, not originating from contemporary plant biomass. This can be explained by anthropogenic disturbance of soils or discharge of radiocarbon–depleted wastewater. However, land enclosure and channel bypassing transformed many rivers from anabranching networks to single–channel systems with overbank sediment accumulation and lowered floodplain groundwater tables. We hypothesized that human development changed the fluvial carbon towards older sources by changing the morphology of watercourses. We studied radiocarbon in the Elbe, a European, anthropogenically–transformed lowland river at discharges between low flow and record peak flow. We found that the inorganic carbon, dissolved organic carbon (DOC) and particulate organic carbon was aged and up to 1850 years old. The ∆14C values remained low and invariant up to median discharges, indicating that the sources of modern carbon (fixed after 1950) were disconnected from the river during half of the time. The total share of modern carbon in DOC export was marginal (0.04%), 72% of exported DOC was older than 400 years. This was in contrast to undisturbed forested subcatchments, 72% of whose exported DOC was modern. Although population density is high, mass balances showed that wastewater did not significantly affect the ∆14C-DOC in the Elbe river. We conclude that wetlands and other sources of contemporary carbon were decoupled from the anthropogenically transformed Elbe stream network with incised stream bed relative to overbank sediments, shifting the sources of fluvial carbon in favor of aged stores.
Climate change attribution and legal contexts: evidence and the role of storylines
Authors: Lloyd Elisabeth A. , Shepherd Theodore G. 
Published: August 2021

AbstractIn a recent very influential court case, Juliana v. United States, climate scientist Kevin Trenberth used the “storyline” approach to extreme event attribution to argue that greenhouse warming had affected and will affect extreme events in their regions to such an extent that the plaintiffs already had been or will be harmed. The storyline approach to attribution is deterministic rather than probabilistic, taking certain factors as contingent and assessing the role of climate change conditional on those factors. The US Government’s opposing expert witness argued that Trenberth had failed to make his case because “all his conclusions of the injuries to Plaintiffs suffer from the same failure to connect his conditional approach to Plaintiffs’ local circumstances.” The issue is whether it is possible to make statements about individual events based on general knowledge. A similar question is sometimes debated within the climate science community. We argue here that proceeding from the general to the specific is a process of deduction and is an entirely legitimate form of scientific reasoning. We further argue that it is well aligned with the concept of legal evidence, much more so than the more usual inductive form of scientific reasoning, which proceeds from the specific to the general. This has implications for how attribution science can be used to support climate change litigation.
“The question is”, said Alice, “whether you can make words mean different things.” “The question is”, said Humpty Dumpty, “which is to be master — that’s all.” (Lewis Carroll, Alice’s Adventures in Wonderland).
Scope Elasticity of Willingness to pay in Discrete Choice Experiments
Authors: Dugstad Anders , Grimsrud Kristine M. , Kipperberg Gorm , Lindhjem Henrik , Navrud Ståle 
Published: August 2021

AbstractSensitivity to scope in nonmarket valuation refers to the property that people are willing to pay more for a higher quality or quantity of a nonmarket public good. Establishing significant scope sensitivity has been an important check of validity and a point of contention for decades in stated preference research, primarily in contingent valuation. Recently, researchers have begun to differentiate between statistical and economic significance. This paper contributes to this line of research by studying the significance of scope effects in discrete choice experiments (DCEs) using thescope elasticity of willingness to payconcept. We first formalize scope elasticity in a DCE context and relate it to economic significance. Next, we review a selection of DCE studies from the environmental valuation literature and derive their implied scope elasticity estimates. We find that scope sensitivity analysis as validity diagnostics is uncommon in the DCE literature and many studies assume unitary elastic scope sensitivity by employing a restrictive functional form in estimation. When more flexible specifications are employed, the tendency is towards inelastic scope sensitivity. Then, we apply the scope elasticity concept to primary DCE data on people’s preferences for expanding the production of renewable energy in Norway. We find that the estimated scope elasticities vary between 0.13 and 0.58, depending on the attribute analyzed, model specification, geographic subsample, and the unit of measurement for a key attribute. While there is no strict and universally applicable benchmark for determining whether scope effects are economically significant, we deem these estimates to be of an adequate and plausible order of magnitude. Implications of the results for future DCE research are provided.
Quantumbit Cosmology Explains Effects of Rotation Curves of Galaxies
Authors: Görnitz Thomas , Schomäcker Uwe 
Published: August 2021

AbstractSome terms identify enigmata of today’s cosmology: “Inflation” is expected to explain the homogeneity and isotropy of the cosmic background. The repulsive force of a “dark energy” shall prevent a re-collapse of the cosmos. The additional gravitational effect of a “dark matter” was originally supposed to explain the deviations of the rotation curves of the galaxies from Kepler’s laws. Adopting a theory founded on the core notion of absolute quantum information–Protyposis–being a cosmological concept from the outset, the observed phenomena can be explained without postulating further unknown specific “particles” or “fields”. Moreover, this theory allows for a rationalization of the fact that huge black holes with their enormous jet structures, acting as “seeds” of the galaxies, are detected ever closer to the big bang. The problem of the rotation curves in the galaxies can be addressed outside of General Relativity within a Newtonian approximation: by an attenuation of the gravitational acceleration as in the modified Newtonian dynamics, or by the effect of additional invisible “particles of dark matter”, yet unknown and not yet established in natural sciences. Within the Protyposis theory, these problems are solved without having to invent a lot of parameters. The cosmology of the Protyposis causes the change of the gravitational acceleration in the vicinity of large (black hole) masses and, at the same time, avoids a recollapse of the cosmos for which a cosmological constant or “dark energy” was invented.