bluuebunny/crossref_metadata_2025_split huggingface dataset:
Zinc Serum Maternal Levels as a Risk Factor for Preeclampsia
Authors: Martadiansyah Abarham , Peby Maulina  , Putri Mirani  , Tia Kaprianti  , Theodorus  
Published: August 2021

Background. Preeclampsia is defined as gestational hypertension and proteinuria which can be measured by the elevation of liver transaminases to twice normal concentration, and the symptoms of increased intracranial pressure such as dizziness, blurred vision, and seizures. Zinc is an essential mineral for many biological functions and one of the trace elements that is directly involved in the oxidative/antioxidant balance, a pathogenesis process in preeclampsia that is highly dependent on dietary habits and supplements. This study was aimed to assess the association between serum zinc level with preeclampsia (PE).
Methods: This observational, case-control study was performed on 90 women with singleton pregnancies at 28 to 42 weeks of gestation which were referred to the Department of Obstetrics and Gynecology, Dr. Mohammad Hoesin General Hospital, Palembang, between August 2020 to November 2020. 30 pregnant women with PE were selected as cases and 60 healthy pregnant women were selected as controls. Maternal serum zinc samples were collected. The collected data were entered into the master table. Tabulation, coding, and statistical data analysis were performed using SPSS version 20.0 for Windows.
Results: The mean serum zinc levels in the case group and control group were 43,90 ± 15,79 µg/dL (ranged from 15 to 86 µg/dL) and 48,77 ± 10,54 µg/dL (ranged from 22 to 83 µg/dL), respectively. A value of serum zinc levels with the best sensitivity and specificity was 45,5 µg/dL.
Conclusion: There was a significant association between maternal serum zinc level with PE. The risk of PE was 3,2 times higher in pregnant women with serum zinc levels of ≤45,5 mcg/dL compared to pregnant women with serum zinc levels of >45,5 mcg/dL. In this case it is necessary to supplement zinc earlier in pregnancy to reduce the risk of preeclampsia.
Analisis Daya Dukung Pondasi Dalam Proyek Pembangunan Gedung Jantung dan Paru-Paru Terpadu RSUD Kabupaten Sukoharjo
Authors: Susilo Susilo 
Published: August 2021

Pondasi tiang atau disebut juga pondasi dalam dipergunakan untuk konstruksi beban berat ( high rise building ). Sebelum melaksanakan suatu pembangunan konstruksi yang pertama-tama dilaksanakan dan dikerjakan dilapangan adalah pekerjaan pondasi (struktur bawah). Pondasi merupakan suatu pekerjaan yang sangat penting dalam suatu pekerjaan teknik sipil, karena pondasi inilah yang memikul dan menahan suatu beban yang bekerja diatasnya yaitu beban konstruksi atas. Tujuan dari studi ini untuk menghitung daya dukung tiang pancang dari hasil sondir, Standart Penetration Test (SPT), dan berdasarkan parameter kuat geser tanah, membandingkan hasil daya dukung tiang pancang dan menghitung penurunan yang terjadi pada tiang pancang. Metodologi pengumpulan data dilakukan dengan cara melakukan observasi, pengambilan data dari pihak proyek serta melakukan studi keperpustakaan. Pada perhitungan daya dukung tiang pancang dilakukan dengan metode Meyerhof dan berdasarkan parameter kuat geser tanah. Berdasarkan data sondir, SPT, parameter kuat geser tanah yang diperoleh dan dihitung . Dari analisis didapat berbagai Alternatif yakni diameter 0,8 m, 0,7 m, 0,6 m, diambil alternatif ke-2 diameter 0,7 m dengan metode Meyerhoff Kapasitas daya dukung pondasi tiang ditentukan oleh kemampuan material tiang untuk menahan beban struktural. Berdasarkan hasil analisis diperoleh tegangan yang terjadi pada tiang sebesar 325,78 Ton > 310 Ton, sehingga pondasi aman digunakan. Analisis tiang kapasitas dukung penurunan tiang pancang metode Meyerhoff diameter 0,8 m sebesar 0,00197 m, 0,7 m sebesar 0,00257 m, 0,6 m sebesar 0,00349 m.
Analisis Penyebab Kerusakan Jalan pada Ruas Jl. Ngadirojo – Giriwoyo
Authors: Satriawan Langgeng 
Published: August 2021

Penelitian ini dilakukan untuk mengetahui penyebab utama kerusakan pada jalan Ngadirojo – Giriwoyo Km. 44 +800 – Km. 46 + 800 dan seberapa parah kerusakan yang ditimbulkan akibat beban yang berlebih (Overload) pada ruas jalan Ngadirojo – Giriwoyo Km. 44 +800 – Km. 46 + 800. Penelitian ini menggunakan metode Observasi, yaitu dengan melaksanakan peninjauan langsung dilapangan, dan data yang bersifat sekunder kami analisis menggunakan program komputer, yaitu Microsoft Exel. Berdasarkan hasil survei kerusakan jalan, jenis kerusakan yang terjadi pada ruas jalan Ngadirojo – Giriwoyo Km. 44 +800 – Km. 46 + 800 adalah Lubang, Retak Refleksi, Sungkur, Stripping, Retak kulit buaya, Pengelupasan permukaan, Jumbul. Kerusakan yang dominan pada ruas jalan Ngdirojo – Giriwoyo Km. 44 +800 – 46 + 800 adalah Sungkur, Lubang, Retak Refleksi. Dari data LHR yang penulis peroleh, bisa dipastikan penyebab utama kerusakan jalan Ngdirojo – Giriwoyo Km. 44 +800 – 46 + 800 dikarenakan oleh kendaraan dengan muatan berlebih (Overload) yang didominasi kendaraan berat atau dalam artian jalan tersebut dipaksakan untuk menerima beban berlebih saat ini. Dari hasil perhitungan pertumbuhan lalulintas (i) dengan metode Eksponensial adalah 7,29 %. Untuk prediksi pertumbuhan lalu lintas ditahun mendatang didapatkan hasil 2019 = 18,47 dengan volume 2825,7 (smp/jam), 2024 = 54,93 % dengan volume 3580,6 (smp/jam) dan 2029 = 91,38 % dengan volume 4335,5 (smp/jam).
Analisis Perkerasan Kaku Metode AASHTO 1993 Dan Metode AUSTROADS 2012 Terhadap Keekonomisan Biaya
Authors: Hartono Muhammad Abi , Latifa Eva Azhra 
Published: August 2021

Terdapat banyak metode dalam mendesain tebal perkerasan kaku, diantaranya metode AASHTO 1993 dan metode AUSTROADS 2012. Pemilihan metode perencanaan yang tepat untuk suatu pekerjaan mempunyai peranan penting terkait dengan indikator keberhasilan suatu proyek dalam hal ini konstruksi perkerasan kaku yang memenuhi syarat teknis dan biaya yang ekonomis. Oleh karena itu, dilakukan penelitian untuk membandingkan tebal pelat beton dan biaya yang diperlukan konstruksi perkerasan kaku dengan lapisan tanah dasar yang diberi perkuatan dengan penambahan semen dibandingkan dengan lapisan tanah dasar yang diberi lapisan geotekstil. Tujuan penelitian ini adalah : menetukan tebal perkerasan kaku dan memilih biaya yang lebih ekonomis. Tebal pelat beton menggunakan metode AASHTO 1993 dan Austroad 2012 dihitung serta dianalisis biaya yang paling ekonomis dari kombinasi tanah dasar, pondasi atas, serta struktur plat beton. Hasil penelitian menunjukkan bahwa apabila menggunakan metode AASHTO 1993 menghasilkan tebal lean concrete 10 cm dan ketebalan pelat beton 27 cm. Sedangkan untuk metode AUSTROADS 2012 menghasilkan tebal lean concrete 10 cm dan ketebalan pelat beton 21 cm. Biaya yang paling murah didapatkan dari kombinasi (Perkerasan AUSTROAD, Tanah Stabilisasi, dan Pondasi Bawah) memerlukan biaya sebesar Rp.71,394,879,243
The role of Karl K. Koststyushko-Valyuzhinich in developing scientific library of Tauric Chersonese State Museum and Heritage Site
Authors: Prokhorova T. A. , Rubanenko N. V. 
Published: August 2021

On July 15 – September 5, 2020, the exhibition “Non-archeological values of the archeological museum” took place at Tauric Chersonese State Museum and Heritage Site. The exhibition revealed the history of the book collection of Karl Kazimirovich Koststyushko-Valyuzhinich (1847−1907), museum founder and first head of excavations. Museum researchers investigate into the origins of the museum scientific library, both the books purchased by the founder and individual publications in the museum book collection. The authors conclude that the museum library was formed, in large part, on the basis Koststyushko Valyuzhinich’s book collection and down to his book preferences. In fact, the unique museum book collection was formed during the lifetime of the outstanding figure. That is the reason for the museum library, and precisely, its part acquired by Koststyushko-Valyuzhinich, to be included into the register of Russian book monuments.
Signal information in the Web of Science Core Collection
Authors: Zakharova S. S. 
Published: August 2021

The author specifies signal information in bibliographies supporting science and research, which enables to use Web of Science Core Collection efficiently. Subscription to the alerts on new arrivals to the Web of Science Core Collection is based upon the preserved search and citation history. The subscribers are researchers and librarians who provide science and research information support. Intensive use of bibliographic databases was expected to replace selective dissemination of information, as the key technological processes of these alerttypes are identical. The author argues that these methods of differentiated bibliographic information services may be combined in providing alerts to researchers; she refers to regular requests as an example. Journal contents in the database may become one more option of individual information retrieval. Subscribers to rapid signal information may receive the alerts on articles published in domestic and foreign journals. These two methods would open up new opportunities within the system of science and research information support.
Subject search in modern library information retrieval systems
Authors: Smirnov Yu. V. 
Published: August 2021

The author reviews in brief the library catalogs as the origins of subject search in the modern search systems. He examines the concept of “subject search”, offers its definition (lacking in the state standards – GOSTs), specifies the types (subject search, search by keywords, systematic search) and characterizes them. The libraries use intensively all three types of subject search while the Internet-based search engines offer just one type, i.e. search by keywords. The universal search systems, like Google and Yandex, do not entail cataloguing, however the possibility of subject search by keywords is designed within html-code and tagging system. The author investigates into the application of systematic search on the Internet. He concludes that this search type emphasizes is intensively applied to the resources related to libraries or science and research (library e-catalogs, abstract databases, etc.). He suggests that in time tagging, the Internet popular subject search system, will tend to classifying and systematic search.
Pain Management and Life Satisfaction In Elderly Individuals: A Single Centred Study
Authors: ÖZER Zülfünaz , BAHÇECİOĞLU TURAN Gülcan , ATAN Gülden 
Published: August 2021

Objective: This study was conducted to find out the pain management status and life satisfaction of elderly individuals living in a nursing home and to determine the relationship between these.
Methods: This descriptive cross-sectional study was conducted in a nursing home in Turkey in November 2019. The data were collected by the researchers with face-to-face interview technique by using “Personal Information Form”, “Geriatric Pain Measure (GPM)”, “Pain Management Inventory (PMI)” and “Life Satisfaction Scale (LSS)”.
Results: GPM total score was 48.95±11.24, and average LSS was 14.37±6.85. There is a positive statistically significant association between GPM and PMI (r=0.385; p
Mutations and expression profile of EDIL3 and correlation with HIF1A and tumor-associated carbonic anhydrases in pancreatic cancer
Authors: AKIN Dilara Fatma , ILIKCI Rahsan 
Published: August 2021

Objective: EDIL3 expression levels are raised in some types of cancer which means that it can be used as a candidate tumor marker. Hypoxia upregulates tumor-associated carbonic anhydrases in cancer genesis. In this study, we aimed to investigate whether EDIL3 plays a role in the hypoxic microenvironment of pancreatic cancer.
Methods: Gene expression and mutation profiles of pancreatic cancer patients and healthy tissue samples were downloaded The Cancer Genome Atlas (TCGA), and the genetic alterations and expression levels of the EDIL3, HIF1A, CA IX and CA XII genes were analyzed. Additionally, PolyPhen-2 and SNAP tools were used to prediction and confirmation of detected alterations pathogenicity and survival analysis was performed.
Results: Expression level of EDIL3, HIF1A and CA IX were found to be statistically significant higher in the patient compared to healthy group and we showed also positive correlation between EDIL3 and HIF1A gene expression. Furthermore, low CA IX and CA XII expression level were found effective on overall survival (p
Adaptation of Chronic Kidney Disease-Self Management Knowledge Tool (CKD-SMKT) into Turkish
Authors: ALTIPARMAK Öznur , İZZETTİN Fikret , OKUYAN Betül , ARIKAN İzzet Hakkı , SANCAR Mesut 
Published: August 2021

Objective: The aim of the study is adaptation of Chronic Kidney Disease-Self Management Tool (CKD-SMKT) into Turkish language.
Material and Methods: The study was conducted with chronic kidney disease patients in a training and research hospital. Initially, translation and cultural adaptation of the Turkish tool was performed, afterwards the internal consistency were evaluated with Kuder-Richardson (KR-20) coefficient.
Results: The total of 48 patients (mean of age [years]: 62.13±15.19) were included the study. An acceptable internal consistency with a KR-20 value of 0.71 were determined for the tool. 62.5% of participants answered correctly to all self-management knowledge items, however only 10.4% of them indicated that they behaved in line with the correct answers of all self-management knowledge items.
Conclusion: The Turkish version of CKD-SMKT is a reliable and appropriate tool to assess the self-management knowledge of chronic kidney patients.
Effect of Education and Monitoring on Developing Foot Care of Elderly with Diabetes Mellitus
Authors: CAN ÇİÇEK Saadet , GÖKDOĞAN Feray 
Published: August 2021

Objective: To determine the effect of education and monitoring on developing foot care in elderly with diabetes.
Methods: This was a controlled experimental a research. The study was performed with diabetes composed of 45 in control group and 45 in intervention group who met inclusion criteria for the study within registered elderly with diabetes in one center of elderly and a public hospital between the dates of September 2012-September 2013. Training and follow-up on foot care was carried out for the intervention group by performing four foot examinations in both groups.
Results: Diabetic foot information and foot care behavior scores showed significantly greater increases in intervention group compared to controls. Significant difference in total foot examination score was determined between groups and in time (p
THE EFFECT OF PH-CYCLING AND TOOTHBRUSHING SIMULATIONS ON SURFACE ROUGHNESS OF BULK-FILL COMPOSITES
Authors: MİSİLLİ Tuğba , GONULOL Nihan , CABADAĞ Özge Gizem , ALMASIFAR Lena , DİNÇ Derya 
Published: August 2021

ABSTRACT
Objective: This study aimed to compare surface roughness values (Ra) of different posterior composites after pH-cycling and toothbrushing simulation.
Methods: Fifty disc-shaped specimens (8x2 mm) were prepared by using three bulk-fill composites [Filtek Bulk Fill Posterior (FBF), SonicFill (SF), X-tra fil (XF)], a flowable [G-aenial Universal Flo (GF)], and a microhybrid composite [Filtek Z250 (Z250)]. After initial roughness (Ra0) measurements were performed with a contact profilometer, the samples were subjected to a pH-cycling model for 10 days and Ra1 values were recorded. Then, the samples were subjected to toothbrushing simulation for 4 min and final values (Ra2) were recorded. From each group, a representative sample was analyzed with an optical profilometer. The values were analyzed by two-way ANOVA with repeated measures on one factor (period) followed by Tukey’s test (p
CAN HYPO-OSMOTIC SWELLING TEST (HOST) IMPROVE PREGNANCY OUTCOMES IN UNEXPLAINED INFERTILITY PATIENTS WITH NORMAL SEMEN PARAMETERS UNDERGOING ICSI –FROZEN EMBRYO TRANSFER CYCLES?
Authors: ÖZDEMİR Ümit , ATAYURT Zafer , ŞIK Bulat Aytek , ÖZDAMAR Özkan , ABA Yılda Arzu , OZOLCAY Ozan 
Published: August 2021

Objective: The objective of this study is to compare the pregnancy outcomes of the couples who underwent Hypo-Osmotıc Swelling Test (HOST)
as a sperm selection method in Intracytoplasmic sperm injection (ICSI) – Frozen embryo transfer (ET) cycles and those who did not.
Methods: ICSI – Frozen ET cycles, employing HOST as a sperm selection method were assigned to the Study Group; whereas those not employing HOST were included in the Control Group. Both study and control groups were divided into two subgroups according to the age of the women; those between the 25-35 years old and those between 36-40. The study and the control group included 509 and 1304 patients; respectively. Patients between 25-40 years old, who received Invitro fertilization (IVF) treatment for the first time, had good quality (grade A) blastocyst embryo on the 5th day, had normal semen parameters and HOST scores of b, c, and d were included in the study.
Results: Pregnancy outcomes were comparable between cycles using HOST and not using HOST in 25-35 years group. However, cycles employing HOST showed significantly higher pregnancy rate (p = 0.023), clinical pregnancy rate (p = 0.005), and live birth rate (p = 0.045) as compared to cycles not using HOST, in the 36-40 years group.
Conclusion:With normal semen parameters, the use of HOST in ICSI-Frozen ET cycles does not increase live birth rates in women aged 25-35, while it increases the rate of live births in women aged 36-40.
Evaluation of the Effectiveness of Distance Learning in Dental Education During COVID-19 Pandemic
Authors: EZBERCİ Sibel , YILDIRIM Bengisu 
Published: August 2021

Objective: COVID-19 pandemic affect dental education as well as everything. Online education become more popular in dentistry nowadays. It was aimed to evaluate the effectiveness of online lessons and satisfaction of the students about distance learning.
Methods: It was asked to respond a 42-items questionnaire at University of Uşak, School of Dentistry. Seven questions were related to demographic data. Thirty-two lickert and three multiple choice questions to determine the quality of current non-clinical and clinical education and to form a guide for future online dental education. The answers were analyzed on IBM SPSS Statistics for Windows, version 22.0 (IBM Corp, Armonk, NY, USA).
Results: This study aimed to reach 316 dental students, of which 302(95.5%) responded (Cronbach Alfa= 0.964). Factor analysis was performed to check the suitability of the data. The Kaiser-Meyer-Olkin measure of sampling adequacy was 0.961 and Barlett’s test of sphericity was significant(p < 0.001). Male students more pleased than female students in term of distance learning(p=0.032). Foreign students felt more comfortable participating actively in online lessons than face-to-face(p=0.047). Fourth grade students were significantly pleased distance learning than first and second grades students(p
Caso Clínico: Citopénia Autoinmune como complicación inmunológica de Trasplante Alogénico de Donante no emparentado, en paciente pediátrico con Anemia Drepanocítica
Authors: Cisneros López Migleth , Maldonado Guerrero Bella , Bonilla Núñez Aníbal , Gonzalez Cabrera Andrés , Andrade Rada Jessica 
Published: August 2021

Introducción: La enfermedad de células falciformes es una condición heredada en la que se produce una hemoglobina anómala que desfavorece a la oxigenación tisular, crisis vaso-oclusivas y reacciones hemolíticas. Los pacientes con esta enfermedad presentan una activación anómala de la vía del complemento llevándolos al aumento en frecuencia de infecciones y enfermedades autoinmunes. Presentamos un caso de asociación de una enfermedad autoinmune en un paciente con enfermedad de células falciforme.
Caso clínico: Niño de 10 años con Anemia drepanocítica (2009) con esplenectomía y crisis veno-oclusivas recurrentes, fue sometido a trasplante Alogénico en abril del 2019 fuera de la institución con donante isogrupo O+ no emparentado (10/10). Tratado con: Fludarabina – Busulfan, Timoglobulina+ y Metotexate. Desarrolló Bicitopenia autoinmune y síndrome febril al día +165 post TPH. Glóbulos blancos: 360 uL, neutrófilos: 14 %, hemoglobina: 7.90 g/dL, plaquetas: 25000 uL, ferritina: 4695 ng/ml, IgG total: 9.88 gr/l, LDH: 190 UI/l. Proteína C reactiva: 2.79 mg/dL, procalcitonina 0.13 ng/mL.
Evolución: posterior a descartar infección viral, se completó un tratamiento antibiótico de amplio espectro y se realizó la suspensión del tratamiento inmunosupresor por sospecha de toxicidad, sin respuesta. Se realizó un estudio medular por citometría de flujo determinando una disminución de la línea linfoide B, y se concluye Citopénia autoinmune como complicación inmunológica del trasplante.
Desenlace: recibió terapia transfusional (plaquetoferesis + glóbulos rojos concentrados). Se utilizó metilprednisolona IV por 3 días y prednisona 30 mg por 14 días con reducción posterior gradual para inicio de Rituximab y ciclosporina. Se completó el tratamiento con Imnunoglobulina 6g IV por 5 días. Al alta glóbulos blancos: 5080 uL, neutrófilos: 67%, hemoglobina: 9.20 g/dL, plaquetas: 20000 uL, después de 18 días de ingreso hospitalario.
Conclusión: Los resultados con el tratamiento en este caso sugieren que puede ser razonable considerar las citopenias autoinmunes como una manifestación hematológica diagnóstica de la EICH crónica. Alternativamente, es posible que el tratamiento de citopenia inmune con esteroides, rituximab y otros inmunosupresores.
Prevalencia de los Genotipos del Virus del Papiloma Humano en mujeres de 25 a 65 años.
Authors: Minchalo Muñoz Diana Janneth , Oleas Seminario Héctor Lincoln , Bigoni Ordóñez Gabriele Davide 
Published: August 2021

Introducción: La infección que ocasiona el Virus del Papiloma Humano (VPH), tiene alta prevalencia en mujeres sexualmente activas. Generalmente es pasajera, pero al existir algunos factores relacionados pueden llegar a desarrollar cáncer cervicouterino. Dado que la enfermedad se desarrolla con lentitud la detección en etapas tempranas ha permitido poner en evidencia la presencia del virus en las células antes que puedan transformarse y volverse tumorigénicas. El objetivo de este estudio fue establecer la prevalencia de los genotipos del Virus del Papiloma Humano en mujeres de 25 a 65 años en un grupo de pacientes de un centro oncológico en Cuenca 2017 – 2018.
Métodos: Es un estudio descriptivo, retrospectivo, analítico, en el cual se recopiló información de las historias clínicas y registros físicos del Laboratorio de Biología Molecular y del sistema médico de SOLCA - Cuenca, SOFTCASE, para establecer la prevalencia de VPH durante el periodo 2017 - 2018. Se utiliza ODDS Ratio para demostrar asociación entre las variables demográficas y los grupos de serología de VPH de riesgo alto versus VPH De riesgo bajo.
Resultados: Se incluyeron 594 casos, con edad entre 36 y 40 años n=103/594 (17.3%). De estado civil casadas n=318/594 (53.5%). Con paridad igual a 2 n=159/594 (26.8%). Casos positivos de VPH fueron 424/594 (71.38%) IC95% (71.23% a 71.53%), Genotipos de alto riesgo con el 58.01%, genotipos de probable bajo riesgo con el 33.25% y genotipos de bajo riesgo 8.72%. La prevalencia del 50% de la población positiva según el genotipo lo explica los VPH 16, 71, 58, 6 y 31. De este grupo los VPH con serología 16, 58 y 31 tienen un riesgo Alto de malignidad. No se reportó asociación entre los VPH de alto riesgo con alguna de las variables demográficas.
Conclusión: El grupo etario con mayor número de casos positivos perteneció a las mujeres de entre 36 y 40 años de edad, con paridad igual a 2 y de estado civil casadas. El subtipo VPH-16 fue el genotipo más prevalente del grupo de alto riesgo de malignidad. El subtipo VPH-71 fue el segundo genotipo más prevalente con un perfil de probable bajo riesgo de malignidad.