bluuebunny/crossref_metadata_2025_split huggingface dataset:
Eosinophilic fasciitis (Shulman syndrome), a rare entity and diagnostic challenge, as a manifestation of severe chronic graft-versus-host disease: a case report
Authors: Chalopin Thomas , Vallet Nicolas , Morel Marion , Maguet Raphael , d’Alteroche Louis , de Pinieux Gonzague , Hérault Olivier , Gyan Emmanuel , Sutton Laurent , Villate Alban 
Published: March 2021

Abstract
Background
Shulman’s disease, or eosinophilic fasciitis (EF), is a rare autoimmune disease, characterized by sclerodermic skin lesions with progressive induration and thickening of the soft tissues. Chronic graft-versus-host-disease (GVHD) presenting as EF is a very rare manifestation of cutaneous GVHD.

Case presentation
We report an unusual case of EF in a 46-year-old Caucasian male patient who had received an allogenic hematopoietic stem cell transplantation in the context of relapsed/refractory multiple myeloma. The diagnosis was challenging, with the patient presenting hepatic dysfunction, normal eosinophils count, and incomplete clinical signs. Magnetic resonance imaging (MRI) and skin biopsy confirmed the diagnosis of EF. Early initiation of specific treatment with corticosteroids and prednisolone achieved complete response.

Conclusion
In practice, incomplete signs in this rare complication should lead to MRI as it is a major tool to guide decision-making based on the skin biopsy, allowing a rapid diagnosis and the initiation of treatment without delay.
The waveform inversion of mainshock and aftershock data of the 2006 M6.3 Yogyakarta earthquake
Authors: Saputra Hijrah , Wahyudi Wahyudi , Suardi Iman , Anggraini Ade , Suryanto Wiwit 
Published: March 2021

AbstractThis study comprehensively investigates the source mechanisms associated with the mainshock and aftershocks of the Mw = 6.3 Yogyakarta earthquake which occurred on May 27, 2006. The process involved using moment tensor inversion to determine the fault plane parameters and joint inversion which were further applied to understand the spatial and temporal slip distributions during the earthquake. Moreover, coseismal slip distribution was overlaid with the relocated aftershock distribution to determine the stress field variations around the tectonic area. Meanwhile, the moment tensor inversion made use of near-field data and its Green’s function was calculated using the extended reflectivity method while the joint inversion used near-field and teleseismic body wave data which were computed using the Kikuchi and Kanamori methods. These data were filtered through a trial-and-error method using a bandpass filter with frequency pairs and velocity models from several previous studies. Furthermore, the Akaike Bayesian Information Criterion (ABIC) method was applied to obtain more stable inversion results and different fault types were discovered. Strike–slip and dip-normal were recorded for the mainshock and similar types were recorded for the 8th aftershock while the 9th and 16th June were strike slips. However, the fault slip distribution from the joint inversion showed two asperities. The maximum slip was 0.78 m with the first asperity observed at 10 km south/north of the mainshock hypocenter. The source parameters discovered include total seismic moment M0 = 0.4311E + 19 (Nm) or Mw = 6.4 with a depth of 12 km and a duration of 28 s. The slip distribution overlaid with the aftershock distribution showed the tendency of the aftershock to occur around the asperities zone while a normal oblique focus mechanism was found using the joint inversion.
Investigations on the general properties of biomass-based aldehyde tanned sheep fur for its selective post-tanning processing
Authors: Ding Wei , Wang Ya-nan , Zhou Jianfei , Liu Haiteng , Pang Xiaoyan , Shi Bi 
Published: March 2021

Abstract
Dialdehyde sodium alginate (DSA) is an alternative chrome-free tanning material for fur production. To obtain satisfactory resultant fur and provide suggestions for the usage of DSA in fur making, the general properties of DSA tanned sheep fur were systematically investigated. The tanning mechanism of DSA was analyzed and it was verified that DSA was mainly combined with collagen fiber by forming Schiff base covalent bonds while supplemented by a small number of hydrogen bonds and ionic bonds. Due to the acid sensitivity of Schiff base structure, DSA tanned fur had poor resistance to acid rinsing but had excellent resistance to washing and good fatliquoring performance. Also, it had good resistances to yellowing and reductant. After being retanned by chrome tanning agent, the fur was capable of enduring a high-temperature dyeing process (68 °C for 8 h). Overall, DSA tanned sheep fur had favorable properties under appropriate post-tanning processing conditions to manufacture light-colored or dark-colored fur products with desirable physical properties.

Graphical abstract
Breast Cancer Research to Support Evidence-Based Medicine in Nigeria: A Review of the Literature
Authors: Fatiregun Omolara A. , Oluokun Temiloluwa , Lasebikan Nwamaka N. , Nwachukwu Emmanuella , Ibraheem Abiola A. , Olopade Olufunmilayo 
Published: March 2021

PURPOSE Breast cancer is the most common malignancy in women worldwide. In Nigeria, it accounts for 22.7% of all new cancer cases among women. Evidence-based medicine (EBM) entails using the results from healthcare research to enhance the clinical decision-making process and develop evidence-based treatment guidelines. Level 1 and 2 studies, such as randomized controlled trials, meta-analyses, and systematic reviews of randomized controlled trials, yield more robust types of evidence. This study reviewed the levels of evidence of breast cancer publications in Nigeria. METHODS We conducted an electronic literature search of all studies published on breast cancer in Nigeria from January 1961 to August 2019. We reviewed all the articles found under the search term “Breast Cancer in Nigeria” on medical databases. RESULTS Our search identified 2,242 publications. One thousand two hundred fifty duplicates were removed, and 520 were excluded. A total of 472 articles were considered eligible for this review. Most of these articles were case series or reports (30.7%), qualitative studies (15.7%), followed by cross-sectional studies (13.3%), laboratory studies (12.9%), case-control studies (6.1%), case reports (7%), and cohort (5.7%). CONCLUSION Breast cancer research in Nigeria is yet to produce much evidence of the types considered to best support EBM. The scarcity of data hampers the implementation of EBM in Nigeria. Currently, most treatment guidelines are adapted from those developed in other countries, despite genetic differences among populations and different environmental influencing factors.
Prenatal Exposure to Butyl Paraben Is Associated With Fat Percentage in 7-Year-Old Boys
Authors: Højsager Frederik Damsgaard , Kyhl Henriette Boye , Frederiksen Hanne , Juul Anders , Andersson Anna-Maria , Andersen Marianne Skovsager , Grøntved Anders , Jensen Tina Kold 
Published: March 2021

Abstract

Context
Parabens are used as preservatives in consumer products but are suspected of having endocrine-disrupting properties. A recent study reported an association between in utero exposure to butyl paraben and overweight in childhood, with a stronger trend in girls.

Objective
We therefore studied the association between parabens in maternal urine in third trimester and fat percentage in children aged 7 years.

Design, Setting, and Participants
We used data from the Odense Child Cohort, a mother-child cohort with enrollment from 2010 to 2012, in which the children are followed. Paraben concentration was assessed in maternal urine at median gestational week 28.7 and body composition measured as total, gynoid, and android fat percentages assessed by dual X-ray absorptiometry in their children at age 7 years.

Main Outcome Measurements
Total, gynoid, and android fat percentages and z-score for body mass index.

Interventions
None.

Results
Paraben exposure was low. In multivariate linear regressions, detection of butylparaben in maternal urine was associated with an increase of 17% [95% confidence intervals (CI) 3.0%, 32%] in total body fat percentage and an increase of 23% (95% CI 5.1%, 43%) in android fat percentage in boys, compared to boys whose mother had no detectable butylparaben in urine. No significant associations between in utero exposure to methyl-, ethyl- or propyl parabens and body composition were found, and no significant associations were seen in girls.

Conclusion
Our findings suggest that parabens, which are believed to have low toxicity, may affect obesity development at vulnerable time periods during development.
From Guerrilla Girls to Zainabs
Authors: Gordon Arielle 
Published: March 2021

AbstractScholars have long accounted for representations of women in the Iranian Revolution by categorically classifying them as “devout mothers” or “heroic sisters,” embodied respectively in the Shiʾi archetypes of Fatima and Zainab. However, a closer look at images of militant women finds them residing within the traditions of their time, as part and parcel of an era of liberation movements in which the idiom of the female fighter featured prominently. This article takes a transnational look at tropes of women’s militancy and traces how they filtered into Iranian revolutionary culture. Finally, it contends that only with the consolidation of Khomeini’s power and the start of the Iran-Iraq War is this figure renamed Zainab and sustained as a central icon of the Islamic Republic.
Documenting the Dead
Authors: Nault Curran 
Published: March 2021

AbstractCall Her Ganda (dir. PJ Raval, 2018) chronicles the murder of transpinay Jennifer Laude by a US marine, and the subsequent court case. This essay draws from theories of necropolitics and hauntology, as well as the author's experience as a documentary producer of Call Her Ganda to raise critical questions about the representation of trans death, and to reflect on the possibilities and limitations of documentary as a trans activist tool. In doing so, the author lays out a looping logic as a parallel proposition to the vortical violences of colonization and transmisogny. This loop begins with the film's apparitional aesthetics, which rouse contemplation of the trans activisms that survive in the wake of trans death, and it continues with the film's activating address and impact campaign. I posit that such efforts can feed back into the communities from which a documentary has been extricated, working through/against the othering and exploitation endemic to documentary practice.
Mammalian primordial germ cell specification
Authors: Hancock Grace V. , Wamaitha Sissy E. , Peretz Lior , Clark Amander T. 
Published: March 2021

ABSTRACT
The peri-implantation window of mammalian development is the crucial window for primordial germ cell (PGC) specification. Whereas pre-implantation dynamics are relatively conserved between species, the implantation window marks a stage of developmental divergence between key model organisms, and thus potential variance in the cell and molecular mechanisms for PGC specification. In humans, PGC specification is very difficult to study in vivo. To address this, the combined use of human and nonhuman primate embryos, and stem cell-based embryo models are essential for determining the origin of PGCs, as are comparative analyses to the equivalent stages of mouse development. Understanding the origin of PGCs in the peri-implantation embryo is crucial not only for accurate modeling of this essential process using stem cells, but also in determining the role of global epigenetic reprogramming upon which sex-specific differentiation into gametes relies.
Arts-based interventions for people living with dementia: Measuring ‘in the moment’ wellbeing with the Canterbury Wellbeing Scales
Authors: Strohmaier Sarah , Homans Karl M. , Hulbert Sabina , Crutch Sebastian J. , Brotherhood Emilie V. , Harding Emma , Camic Paul M. 
Published: March 2021

Background: There is growing acknowledgement for the need to move beyond exclusive biomedical understandings of dementia and also focus on how to improve the lives and wellbeing of people living with dementia. A mounting body of research advocates for the benefits of arts-based interventions for this population. The purpose of this study was to explore the links between multiple components of arts-based interventions and subjective wellbeing in order to help assess if these activities might contribute to meaningful community-based dementia care initiatives. Methods: Using previously collected data across different intervention sites, a within- and between- participants design was used that assessed wellbeing through the Canterbury Wellbeing Scales (CWS) in people with mild-to-moderate dementias (N = 201) who participated in various community arts-based interventions (ABI). Data were analysed using non-parametric statistical analyses and bootstrapped moderation models. Results: Increases in subjective wellbeing were associated with all forms of ABI. Co-creative sessions significantly strengthened the relationship between number of sessions attended and overall wellbeing as well as optimism. No significant moderating effect was observed between number of sessions attended and carer presence. Conclusions: In the largest study of its kind to date to assess wellbeing using arts activities in a community-based dementia sample, findings support the use and acceptability of the CWS as a measurement tool for people with early-to-middle stages of dementia and suggest that the CWS can reliably measure wellbeing in this population. In addition, the positive effect of arts-based interactions on specific aspects of wellbeing were found, which provide a better understanding of the conditions under which these effects can be prolonged and sustained. Further research is needed to better understand the environmental, social, and psychological mechanisms through which these improvements operate.
Lower urinary tract symptoms and sexual functioning in patients with depression
Authors: Przydacz Mikolaj , Golabek Tomasz , Skalski Michal , Sobanski Jerzy , Choragwicki Dominik , Klasa Katarzyna , Pyrkosz Pawel , Dudek Dominika , Chlosta Piotr 
Published: March 2021

Cel pracyW literaturze wykazano związek między depresją a funkcjonowaniem seksualnym. Nadal jednak nie wiadomo, czy u osób z depresją, objawy dolnych dróg moczowych (ang. Lower Urinary Tract Symptoms, LUTS) współistnieją z zaburzeniami seksualnymi (ang. Sexual Dysfunction, SD) oraz czy z nimi korelują. Pacjenci z depresją stanowią wyjątkową populację ze względu na możliwy dwukierunkowy związek między SD a depresją, a także LUTS i depresją. Zatem celem tego eksperymentu było zbadanie u pacjentów z depresją zależności między stopniem nasilenia depresji, SD i LUTS.MetodaW tym przekrojowym badaniu przeanalizowano dane dotyczące depresji, funkcjonowania seksualnego oraz LUTS u pacjentów leczonych w oddziale psychiatrii dorosłych naszego szpitala. Zastosowano skalę oceny depresji Hamiltona, międzynarodowy wskaźnik funkcji erekcyjnej (IIEF), wskaźnik funkcjonowania seksualnego kobiet (FSFI) i międzynarodowy wskaźnik objawów towarzyszących chorobom prostaty (IPSS).WynikiStu dwóch pacjentów ze zdiagnozowaną i leczoną depresją zostało włączonych do badania. Stwierdzono wysoką częstość występowania SD (60,8%), a SD korelowało ze stopniem nasilenia depresji. LUTS były również bardzo rozpowszechnione, a 86% uczestników zgłaszało co najmniej łagodne nasilenie LUTS. Pomimo tego, że LUTS i SD współistniały u wielu pacjentów, w naszej kohorcie nie znaleźliśmy istotnej statystycznie różnic między LUTS i SD.WnioskiW naszej grupie pacjentów, u których zdiagnozowano i leczono depresję, nasilenie depresji miało negatywny wpływ na funkcjonowanie seksualne. Chociaż pomiędzy LUTS i SD nie było istotnych statystycznie różnic, współistniały one u wielu pacjentów. Dlatego LUTS i SD powinny być nadal wspólnie oceniane u pacjentów z depresją.
Comparison of diagnostic performances of ten different immunoassays detecting anti-CCHFV IgM and IgG antibodies from acute to subsided phases of Crimean-Congo hemorrhagic fever
Authors: Emmerich Petra , von Possel Ronald , Deschermeier Christina , Ahmeti Salih , Berisha Lindita , Halili Bahrije , Jakupi Xhevat , Sherifi Kurtesh , Messing Claudia , Borchardt-Lohölter Viola 
Published: March 2021

Crimean-Congo Hemorrhagic Fever Virus (CCHFV) is a geographically widespread tick-borne arbovirus that has been recognized by the WHO as an emerging pathogen needing urgent attention to ensure preparedness for potential outbreaks. Therefore, availability of accurate diagnostic tools for identification of acute cases is necessary.
A panel comprising 121 sequential serum samples collected during acute, convalescent and subsided phase of PCR-proven CCHFV infection from 16 Kosovar patients was used to assess sensitivity. Serum samples from 60 healthy Kosovar blood donors were used to assess specificity. All samples were tested with two IgM/IgG immunofluorescence assays (IFA) from BNITM, the CCHFV Mosaic 2 IgG and IgM indirect immunofluorescence tests (IIFT) from EUROIMMUN, two BlackBox ELISAs for the detection of CCHFV-specific IgM and IgG antibodies (BNITM), two Anti-CCHFV ELISAs IgM and IgG from EUROIMMUN using recombinant structural proteins of CCHFV antigens, and two ELISAs from Vector-Best (IgM: μ-capture ELISA, IgG: indirect ELISA using immobilized CCHFV antigen). Diagnostic performances were compared between methods using sensitivity, specificity, concordance and degree of agreement with particular focus on the phase of the infection.
In early and convalescent phases of infection, the sensitivities for detecting specific IgG antibodies differed for the ELISA test. The BlackBox IgG ELISA yielded the highest, followed by the EUROIMMUN IgG ELISA and finally the VectorBest IgG ELISA with the lowest sensitivities. In the subsided phase, the VectorBest IgM ELISA detected a high rate of samples that were positive for anti-CCHFV IgM antibodies. Both test systems based on immunofluorescence showed an identical sensitivity for detection of anti-CCHFV IgM antibodies in acute and convalescent phases of infection.
Available serological test systems detect anti-CCHFV IgM and IgG antibodies accurately, but their diagnostic performances vary with respect to the phase of the infection.
Reliability of dried blood spot (DBS) cards in antibody measurement: A systematic review
Authors: Amini Fahimah , Auma Erick , Hsia Yingfen , Bilton Sam , Hall Tom , Ramkhelawon Laxmee , Heath Paul T. , Le Doare Kirsty 
Published: March 2021

BackgroundIncreasingly, vaccine efficacy studies are being recommended in low-and-middle-income countries (LMIC), yet often facilities are unavailable to take and store infant blood samples correctly. Dried blood spots (DBS), are useful for collecting blood from infants for diagnostic purposes, especially in low-income settings, as the amount of blood required is miniscule and no refrigeration is required. Little is known about their utility for antibody studies in children. This systematic review aims to investigate the correlation of antibody concentrations against infectious diseases in DBS in comparison to serum or plasma samples that might inform their use in vaccine clinical trials.Methods and findingsWe searched MEDLINE, Embase and the Cochrane library for relevant studies between January 1990 to October 2020 with no language restriction, using PRISMA guidelines, investigating the correlation between antibody concentrations in DBS and serum or plasma samples, and the effect of storage temperature on DBS diagnostic performance.We included 40 studies in this systematic review. The antibody concentration in DBS and serum/plasma samples reported a good pooled correlation, (r2= 0.86 (ranged 0.43 to 1.00)). Ten studies described a decline of antibody after 28 days at room temperature compared to optimal storage at -20°C, where antibodies were stable for up to 200 days. There were only five studies of anti-bacterial antibodies.ConclusionsThere is a good correlation between antibody concentrations in DBS and serum/plasma samples, supporting the wider use of DBS in vaccine and sero-epidemiological studies, but there is limited data on anti-bacterial antibodies. The correct storage of DBS is critical and may be a consideration for longer term storage.
A Rasch analysis of emerging adults’ health motivation questionnaire in higher education context
Authors: An Min , Yu Xiaofei 
Published: March 2021

Objective
The College Students’ Health Motivation Questionnaire (CSHM-Q) is used to measure motivation for a healthy lifestyle among emerging adults. This study sought to validate the CSHM-Q using the Rasch measurement model.

Methods
322 participants were recruited based on a convenience sampling method. The Rasch analysis was carried out using the RUMM2030 software.

Results
Local item dependency was accommodated using the ‘super item’ approach. Disordered thresholds were resolved by collapsing some response options. After modification, each component of the CSHM-Q showed acceptable overall fit, item and person fit, internal consistency, and targeting. Unidimensionality was supported at the subscale level. Items did not exhibit disordered threshold, local item dependency, or differential item functioning. Transforming tables were also created to help convert the raw score into an interval scale.

Conclusions
Results of the Rasch analysis supported the interval scale measurement properties of the CSHM-Q and offered health education researchers an instrument to measure emerging adults’ health motivation in the higher education context.
Factors associated with domestic violence in the Lahu hill tribe of northern Thailand: A cross-sectional study
Authors: Panjaphothiwat Nicharuch , Tamornpark Ratipark , Apidechkul Tawatchai , Seeprasert Prapamon , Singkhorn Onnalin , Upala Panupong , Thutsanti Phitnaree , Yeemard Fartima , Sunsern Rachanee 
Published: March 2021

Background
Domestic violence significantly affects physical and mental health, particularly among children, women, and the elderly. Living in certain family environments could lead to victimization by domestic violence, especially among families with a poor socioeconomic status, such as the Lahu hill tribe people in Thailand. This study aimed to estimate the prevalence of and determine the factors associated with domestic violence among Lahu children, women, and the elderly.

Methods
A cross-sectional study was conducted of participants who belonged to the Lahu hill tribe and lived in 20 selected villages in Chiang Rai Province, Thailand. A validated questionnaire was used to collect personal information and information regarding experiences related to domestic violence in the past year from children (aged 5–15 years), women (aged 16–59 years), and the elderly (aged 60 years and over). A binary logistic regression was used to detect associations between the variables.

Results
A total of 646 participants were recruited into the study, specifically, 98 children aged 5–15 years, 430 women aged 16–59 years, and 118 elderly people. Children who smoked (AOR = 8.70; 95%CI = 1.27–59.45) had greater odds of experiencing domestic violence than children who did not smoke. Women who had a role as a family member (AOR = 1.59; 95%CI = 1.02–2.50), used alcohol (AOR = 3.36; 95%CI = 2.27–4.99), lived in a family with financial problems (AOR = 4.01; 95%CI = 2.52–7.66), and lived with a family member who uses alcohol (AOR = 2.87; 95%CI = 2.20–5.63) had greater odds of suffering domestic violence than women who did not share these characteristics. The elderly who used alcohol (AOR = 3.25, 95%CI = 1.08–9.81), lived with a family member who uses alcohol (AOR = 3.31; 95%CI = 1.26–7.34), or lived in a family with financial problems in the past year (AOR = 2.16; 95%CI = 1.16–8.77) had greater odds of facing domestic violence than the elderly who did not have these characteristics.

Conclusion
Family financial problems and substance use are associated with domestic violence in Lahu families in Thailand. Health interventions to reduce the use of substances, including training programs to respond to domestic violence, should be promoted for Lahu children, women, and the elderly.