bluuebunny/crossref_metadata_2025_split huggingface dataset:
Una serie inédita del pintor murillesco Juan Francisco Garzón (ca. 1660-1694) sobre La vida de la Virgen (ca. 1692-1694)
Authors: Cruz Isidoro Fernando 
Published: November 2021

Se identifica una serie de doce cuadros, con la Vida de la Virgen María, del pintor sevillano, poco conocido, Juan Francisco Garzón (ca.1660-1694), que formó parte de la escuela murillesca del último tercio del siglo XVII. Varios de los lienzos conservan su firma, lo que permite documentarlos y el análisis de su estilo para la caracterización de su personalidad artística. Se conserva íntegra en la iglesia del monasterio de dominicas de Madre de Dios de Sanlúcar de Barrameda (Cádiz).
Invasive alien plant species distributed as weeds in arable land in Bulgaria
Authors: Zahariev Dimcho , Ivanova Nina , Nasuf Aishe 
Published: November 2021

Abstract
26 species of invasive alien plant species enter the arable land in Bulgaria as weeds. Some of these species are already causing economic damage and are included in the list of the 100 most economically important weeds. For others, it is only a matter of time before they are included in this list. Possessing a complex of qualities, they spread quickly and aggressively, occupying new areas and settling permanently in them. As artificial habitats in which there is no permanent vegetation, arable land is one of the easiest terrains to invade. The study examines the biological characteristics that determine the invasive nature of this group of plants, their origin, distribution routes, weed crops and control measures that can be taken. Particular attention shall be paid to the additional effects that these species may have on human health, on cultivated crops and on natural habitats located in the neighborhood.
On the non existence of periodic orbits for a class of two dimensional Kolmogorov systems
Authors: Boukoucha Rachid 
Published: November 2021

Abstract
In this paper we characterize the integrability and the non-existence of limit cycles of Kolmogorov systems of the form

x
′

=
x

(

B

1

(

x
,
y

)

ln

|

A

3

(

x
,
y

)

A

4

(

x
,
y

)

|

+

B

3

(

x
,
y

)

ln

|

A

1

(

x
,
y

)

A

2

(

x
,
y

)

|

)

,

y
′

=
y

(

B

2

(

x
,
y

)

ln

|

A

5

(

x
,
y

)

A

6

(

x
,
y

)

|

+

B

3

(

x
,
y

)

ln

|

A

1

(

x
,
y

)

A

2

(

x
,
y

)

|

)

\matrix{{x' = x\left( {{B_1}\left( {x,y} \right)\ln \left| {{{{A_3}\left( {x,y} \right)} \over {{A_4}\left( {x,y} \right)}}} \right| + {B_3}\left( {x,y} \right)\ln \left| {{{{A_1}\left( {x,y} \right)} \over {{A_2}\left( {x,y} \right)}}} \right|} \right),} \hfill \cr {y' = y\left( {{B_2}\left( {x,y} \right)\ln \left| {{{{A_5}\left( {x,y} \right)} \over {{A_6}\left( {x,y} \right)}}} \right| + {B_3}\left( {x,y} \right)\ln \left| {{{{A_1}\left( {x,y} \right)} \over {{A_2}\left( {x,y} \right)}}} \right|} \right)} \hfill \cr }

where A
1 (x, y), A
2 (x, y), A
3 (x, y), A
4 (x, y), A
5 (x, y), A
6 (x, y), B
1 (x, y), B
2 (x, y), B
3 (x, y) are homogeneous polynomials of degree a, a, b, b, c, c, n, n, m respectively. Concrete example exhibiting the applicability of our result is introduced.
Sensitivity Analysis for Effect of Changes in Input Data on Hydrological Parameters and Water Balance Components in the Catchment Area of Hungarian Lowland
Authors: Tran Hop Quang 
Published: November 2021

Abstract
Extreme weather and climate changes are emerging more frequently in Central Europe, Hungary, and in the near future the increase in prolonged droughts, high-intensity precipitation events and the temporal variations of precipitation are expected, which may increase the magnitude of local water damages (OVF, 2016). As a result of climate change, these extreme weather events will be more frequent, however it is difficult to predict them, as until now insufficient amount of observations are available on smaller watercourses and on refined territorial water balances. For the future assessment of the environmental and economic impacts of climate change, it is essential to explore the integrated relationship of evapotranspiration, runoff, infiltration, surface and subsurface waters, and other hydrological processes, which can fundamentally describe regionally the water management conditions.
In this research, an earlier study (DHI Hungary 2019) on the catchment area of the main canal of the Dong-ér Brook is pursued to continue the development of the MIKE SHE model in a more complex manner. Within the frame of the present study, the relationship between the individual hydrological parameters, the water balance components and extreme precipitation events (drought, heavy rainfall events) for the entire drainage basin have been examined, besides, the expected effects of the predicted temperature rise on the water balance is evaluated. Using data from 2018 as reference, the sensitivity of the changes in daily precipitation and daily mean temperature has been assessed to estimate the effects of the future climate change on hydrological parameters and water balance components.
Hypofractionated preoperative radiotherapy for high risk soft tissue sarcomas in a geriatric patient population
Authors: Potkrajcic Vlatko , Traub Frank , Hermes Barbara , Scharpf Marcus , Kolbenschlag Jonas , Zips Daniel , Paulsen Frank , Eckert Franziska 
Published: November 2021

Abstract

Background
Standard therapy for localised, resectable high risk soft tissue sarcomas consists of wide excision and radiotherapy over several weeks. This treatment schedule is hardly feasible in geriatric and frail patients. In order not to withhold radiotherapy from these patients, hypofractionated radiotherapy with 25 Gy in 5 fractions was evaluated in a geriatric patient population.

Patients and methods
A retrospective analysis was performed of 18 geriatric patients with resectable high risk soft tissue sarcomas of extremities and thoracic wall. Wound healing and short term oncologic outcome were analysed. In addition, dose constraints for radiotherapy of the extremities were transferred from normofractionated to hypofractionated radiotherapy regimens.

Results
Feasibility was good with 17/18 patients completing treatment as planned. Wound healing complication rate was in the range of published data. Two patients developed local and distant recurrence, two patients isolated distant recurrences. No isolated local recurrences were observed. Keeping the constraints was possible in all cases without compromising the coverage of the target volume.

Conclusions
Hypofractionated radiotherapy and surgery was well tolerated even in this specific patient population. With feasibility concerning early wound healing problems and adapted constraints, which allow for the treatment of most resectable extremity tumours, the concept warrants further evaluation in patients unfit for standard radiotherapy.
MitomiRs: their roles in mitochondria and importance in cancer cell metabolism
Authors: Rencelj Andrej , Gvozdenovic Nada , Cemazar Maja 
Published: November 2021

Abstract

Background
MicroRNAs (miRNAs) are short non-coding RNAs that play important roles in almost all biological pathways. They regulate post-transcriptional gene expression by binding to the 3’untranslated region (3’UTR) of messenger RNAs (mRNAs). MitomiRs are miRNAs of nuclear or mitochondrial origin that are localized in mitochondria and have a crucial role in regulation of mitochondrial function and metabolism. In eukaryotes, mitochondria are the major sites of oxidative metabolism of sugars, lipids, amino acids, and other bio-macromolecules. They are also the main sites of adenosine triphosphate (ATP) production.

Conclusions
In the review, we discuss the role of mitomiRs in mitochondria and introduce currently well studied mitomiRs, their target genes and functions. We also discuss their role in cancer initiation and progression through the regulation of mRNA expression in mitochondria. MitomiRs directly target key molecules such as transporters or enzymes in cell metabolism and regulate several oncogenic signaling pathways. They also play an important role in the Warburg effect, which is vital for cancer cells to maintain their proliferative potential. In addition, we discuss how they indirectly upregulate hexokinase 2 (HK2), an enzyme involved in glucose phosphorylation, and thus may affect energy metabolism in breast cancer cells. In tumor tissues such as breast cancer and head and neck tumors, the expression of one of the mitomiRs (miR-210) correlates with hypoxia gene signatures, suggesting a direct link between mitomiR expression and hypoxia in cancer. The miR-17/92 cluster has been shown to act as a key factor in metabolic reprogramming of tumors by regulating glycolytic and mitochondrial metabolism. This cluster is deregulated in B-cell lymphomas, B-cell chronic lymphocytic leukemia, acute myeloid leukemia, and T-cell lymphomas, and is particularly overexpressed in several other cancers. Based on the current knowledge, we can conclude that there is a large number of miRNAs present in mitochondria, termed mitomiR, and that they are important regulators of mitochondrial function. Therefore, mitomiRs are important players in the metabolism of cancer cells, which need to be further investigated in order to develop a potential new therapies for cancer.
Determinants of the effective tax burden of companies in the Telecommunications activities in the Republic of Croatia
Authors: Bubanić Marijana , Šimović Hrvoje 
Published: November 2021

Abstract
The aim of this paper is to identify the determinants of the effective tax burden of companies in the activity division Telecommunication in the Republic of Croatia. The research covers the time interval from 2008 to 2017. Dynamic panel analysis was used to conduct the research. Microeconomic data were obtained from the databases of the Financial Agency, and macroeconomic data from the Central Bureau of Statistics. The results indicate that the effective tax burden of companies in the activity division Telecommunication is affected by the effective tax burden from the previous period, company size, leverage, inventory intensity, profitability and economic cycle. While capital and labour intensity didn`t prove statistically significant. The main limitations of the research lie in the impossibility of generalizing the stated results to all companies from the observed activity, using only one evaluation model, and being a cabinet-type research, without confirmation of the results obtained by companies. The research received several scientific contributions: this is the first study of the determinants of the effective tax burden conducted in the Republic of Croatia; the research covers an entire activity whit different companies sizes, and not as in most previous research, which mainly include only large companies listed on the stock exchange; unlike previous studies that used a balanced sample, and in most cases static panel models, this study used an unbalanced sample and a dynamic panel model.
Knowledge Hiding: One of the Primary Reasons behind the Rapid Spread of the Novel Coronavirus COVID-19
Authors: Issac Abraham Cyril 
Published: November 2021

Abstract
The world is battling out the pandemic of Covid-19. The World Health Organization (WHO) is jointly acting upon the same daily, which is evident from the ‘situation reports.’ The pandemic, which saw its origin in Wuhan, has spread across the world within a short span of under two months. While the pandemic has effectively instilled a situation of cordon sanitaire across the globe, the virus seems to show no respite. This study collates different sources and establishes the human tendency of knowledge hiding as the prime reason for the spread of such colossal magnitudes. The study underlines the notion by examining some of the critical cases and situations that have unfolded in the very recent past.
Penggambaran Qilin pada Mimbar Masjid Gedhe Mataram Kotagede: Kajian Arkeologi Seni
Authors: Raffi Naufal , Kumalasari Dyah Kumalasari , Yusuf Sandy Maulana Yusuf 
Published: November 2021

Interaksi antarbudaya dalam kajian arkeologi seni memungkinkan corak budaya tertentu muncul di artefak budaya lain. Tujuan dari penelitian ini adalah mengetahui latar belakang kemunculan ornamen figur qilin pada mimbar Masjid Gedhe Mataram Kotagede, beserta teknik penggambaran dan prinsip-prinsip seni yang melekat padanya. Metode penelitian yang digunakan dalam penelitian ini ialah kualitatif deskriptif dengan pendekatan arkeologi seni dan ikonografi. Dari hasil wawancara diketahui bahwa ornamen qilin merupakan pemberian dari Sultan Palembang. Ornamen ini menjadi bukti adanya pengaruh Tiongkok di Nusantara. Qilin pada mimbar Masjid Gedhe Mataram Kotagede digambarkan dengan teknik denaturalistis atau stilasi. Penggambaran qilin memperhatikan prinsip-prinsip seni rupa. Prinsip-prinsip tersebut antara lain kesatuan, keseimbangan, irama, dan kesebandingan simbol.

Intercultural interactions, in relation to the study of art archeology, have allowed certain cultural features to appear in other cultural artefacts. The aim of this study was to put forward the reasons behind the appearance of the qilins on the pulpit of the Masjid Gedhe Mataram in Kotagede, along with the depiction techniques and art principles attached to it. The research method used in this study was descriptive qualitative with an art archaeological and iconographical approach. The study indicated that the pulpit was a gift from Sultan of Palembang, demonstrating Chinese influence in this archipelagic nation (Nusantara). The qilins were portrayed using denaturalization or stylized techniques, highlighting the principles of fine art such as unity, balance, rhythm, and proportionality of symbol.
DETEKSI KECURANGAN LAPORAN KEUANGAN DENGAN METODE FRAUD DIAMOND PADA PERUSAHAAN JASA
Authors: Nor Aini Aprilia Selvia Renzy , Furqani Astri 
Published: November 2021

Kecurangan dalam penyajian laporan keuangan merupakan hal yang sangat urgent dan jadi perhatian, khususnya di dunia perbankan yang beberapa tahun belakangan telah terjadi kecurangan. Dan supaya tindakan ini dapat terdeteksi dan dapat dihilangkan, sehingga laporan keuangan bisa dipercaya oleh para pemegang kepentingan seperti investor, kreditor dan masyarakat.Penelitian ini menggunakan metode kuantitatif deskriptif. Penelitian ini dilakukan pada perusahaan jasa sub sektor bank dengan menggunakan metode purposive sampling untuk penentuan sampel dengan jumlah populasi sebanyak 43 perusahaaan dan sampel sebanyak 22 perusahaan. Jenis data yang digunakan adalah data primer dan menggunakan metode analisis yang digunakan dalam penelitian ini adalah statistik deskriptif, analisis regresi linear berganda dan uji hipotesis dengan program SPSS versi 22. Berdasarkan pada hasil dari pengujian hipotesis yang dilakukan pada penelitian ini membuktikan 8 hipotesis pada penelitian ini, yaitu (1) Financial Targets berpengaruh negatif terhadap kecurangan laporan keuangan. (2) Financial Stability berpengaruh negatif terhadap kecurangan laporan keuangan. (3) External Pressure berpengaruh negatif terhadap kecurangan laporan keuangan. (4) Nature of Industry berpengaruh positif terhadap kecurangan laporan keuangan. (5) Ineffective Monitoring berpengaruh positif terhadap kecurangan laporan keuangan. (6) Opini Auditor berpengaruh negatif terhadap kecurangan laporan keuangan. (7) Rationalization berpengaruh positif terhadap kecurangan laporan keuangan. (8) Capability tidak berpengaruh terhadap kecurangan laporan keuangan.
Responsabilidad social y cooperativismo. El Fondo de Educación y Promoción (FEP) como indicador social en el caso del cooperativismo de crédito
Authors: Server Izquierdo Ricardo J. , Villalonga Grañana Inmaculada 
Published: November 2021

La Responsabilidad Social de la Empresa (RSE) conduce a un modelo de entidad que amplía su preocupación, de forma voluntaria, aglutinando a un mismo nivel aspectos económicos, sociales y medioambientales, debiéndose considerar su introducción en las estrategias empresariales, más como una inversión que como un gasto, ya que aportará a la entidad una ventaja competitiva que asegurará su viabilidad a largo plazo ante la demanda de la sociedad de comportamientos empresariales socialmente responsables.En el presente trabajo se revisa la interrelación existente entre los postulados del comportamiento socialmente responsable y lo que se indica en los principios en los que basan su comportamiento las Sociedades Cooperati vas, poniendo de manifiesto que el Fondo de Educación y Promoción, partida singular y característica de las mismas, es un indicador válido para evaluar la RSE en el cooperativismo de crédito, ya que en su aplicación se recogen los aspectos más relevantes atribuidos a un comportamiento socialmente responsable.
Problemas econométricos de los modelos de diferencias en diferencias
Authors: Vicens Otero José 
Published: November 2021

Los modelos de diferencias en diferencias (DD) son posiblemente la especificación econométrica más utilizada para analizar el efecto o impacto de un cambio sobre un sistema. La mayoría de sus aplicaciones se basan en datos de unidades o sujetos, por lo que puede considerarse a la metodología utilizada como perteneciente al campo de la microeconometría. Sus aplicaciones se centran en el contexto de experimentos naturales o cuasiexperimentos, dónde el cambio es exógeno y el diseño o elección de los grupos de control y tratamiento son consecuencia del cambio, a diferencia de la experimentación clásica donde los grupos de control y tratamiento se diseñan y escogen aleatoriamente. Sus aplicaciones en el análisis económico han sido múltiples, pero desgraciadamente la mayoría de los análisis se han fijado en los resultados y sus consecuencias, pasando por alto, salvo honrosísimas excepciones, ciertos problemas que afectan directamente a los resultados econométricos de la estimación. En el presente trabajo se desarrollan y plantean soluciones para los tres problemas econométricos más importantes en este tipo de aplicaciones: Endogeneidad, Correlación Intragrupo y Autocorrelación.
Análisis integral como sistema de medición y gestión de capitales intangibles en organizaciones y territorios
Authors: López Ruiz Víctor Raúl , Nevado Peña Domingo 
Published: November 2021

En la sociedad del conocimiento, resulta necesario disponer de nuevos instrumentos de medición y de gestión para todos los intangibles que generan valor, no solamente para las organizaciones empresariales sino también para los territorios nacionales, regionales o locales. Los métodos más extendidos se han iniciado en el ámbito empresarial, sirviendo de soporte a los modelos macro implementados en los últimos años, bajo la hipótesis del conocimiento como nuevo generador de riqueza. En este marco, presentamos el método de Análisis Integral como sistema válido para la medición de capitales intangibles en las organizaciones, con ventajas sobre su promotor: el Navegador de Skandia. También, como herramienta para la gestión, planificación y auditoría de la estrategia, avanzando sobre el Cuadro de Mando Integral. Por último, desde una perspectiva macroeconómica, como generador de indicadores de competitividad y factores de crecimiento para los territorios.
Índices de valor unitario del comercio exterior de la Región de Murcia y contribución de las exportaciones al crecimiento regional
Authors: Buendía Azorín José Daniel , Esteban Yago Miguel A. , Sánchez De La Vega José Carlos 
Published: November 2021

El objetivo de este artículo es el cálculo de los índices de valor unitario del comercio exterior de la Región de Murcia en el periodo 2000-2005 a partir de la metodología y fuentes de información utilizadas en la elaboración de los índices nacionales. Los resultados se presentan desagregados en dos áreas geográficas, estados miembros de la UE y países no-UE, y en función del destino económico. A partir de los resultados obtenidos se realiza una primera aplicación al cálculo de las contribuciones al crecimiento regional de las exportaciones.
Relación entre los mitos románticos y las actitudes hacia la igualdad de género en la adolescencia
Authors: Rivas-Rivero Esther , Bonilla-Algovia Enrique 
Published: November 2021

La desigualdad y la violencia de género son graves problemas que afectan a todas las culturas, cuyo origen se encuentra, entre otros, en la socialización diferencial y en las prácticas relacionales androcéntricas instauradas a través de distintos mecanismos. El presente estudio, de corte transversal y diseño ex-post-facto, pretende conocer la asociación entre los mitos del amor romántico y las actitudes hacia la igualdad en una muestra de 1,840 adolescentes de Educación Secundaria Obligatoria de Castilla-La Mancha. Los resultados reportan que los perfiles más favorables hacia la desigualdad de género aceptan en mayor medida los mitos del amor romántico. Además, las actitudes menos favorables hacia la coeducación en el plano relacional permiten explicar tanto la idealización del amor romántico como la vinculación amor-maltrato. Finalmente, se hallaron diferencias entre hombres y mujeres de perfil sexista en la mayor aceptación de la dimensión vinculación amor-maltrato. En conclusión, es fundamental incorporar el enfoque coeducativo en las aulas con el fin de eliminar la desigualdad y la asimilación del ideario del amor romántico, el cual se sustenta en formas relacionales basadas en la dependencia y genera asimetrías en las relaciones afectivas.