bluuebunny/crossref_metadata_2025_split huggingface dataset:
The use of music for children and adolescents living with rare diseases in the healthcare setting: a scoping review study protocol
Authors: Karpaviciute Simona , Sweeney Alison , O‘Neill Aimee , McNulty Sandra , Kroll Thilo , Somanadhan Suja 
Published: May 2021

Background: Interest in the application of music in the health, social care and community contexts is growing worldwide. There is an emerging body of literature about the positive effects of music on the well-being and social relationships of children and adult populations. Music has also been found to promote social interaction, communication skills, and social-emotional behaviours of children with medically complex care needs. Despite significant advancements in the area, to the authors’ knowledge, this is the first scoping review to investigate the evidence for using music therapy and music-based interventions for children living with rare diseases in the healthcare setting. Therefore, the purpose of this study is to conduct a scoping review of the literature to map out the existing studies about the use of music therapy and music-based interventions with children who have rare diseases in the healthcare setting. This review will also identify gaps in current knowledge and use of these interventions. Method: This study follows the Joanna Briggs Institute’s methodology for scoping reviews, utilising Arksey and O’Malley’s six-stage scoping review framework: 1) identifying the research question; 2) identifying relevant studies; 3) study selection; 4) charting the data; 5) collating, summarising and reporting results; and 6) consulting with relevant stakeholders step. A comprehensive search will be conducted in CINAHL Complete; MEDLINE Complete; Psychology and Behavioral Sciences Collection; and PubMed Central databases. A search strategy with selected inclusion and exclusion criteria will be used to reveal a wide range of evidence. This study will include quantitative, qualitative and mixed research methods studies published in English from 2010 to 2020.
Watt-level superfluorescent fiber source near 3  µm
Authors: Yang Lingling , Wu Jiadong , Li Ning , Duan Qinwen , Liu Dongyang , Miao Lili , Zhao Chujun 
Published: May 2021

We report a watt-level mid-infrared (mid-IR) superfluorescent fiber source from

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r

3
+

-doped ZBLAN fiber near 3 µm spectral range. With the power amplifier configuration, the mid-IR superfluorescent fiber source with power up to 1.85 W has been delivered successfully with slope efficiency about 18.6%. The experimental results may pave an avenue toward a high-power, high-temporal-stability superfluorescent source for versatile mid-IR applications.
Circulating neprilysin hypothesis: A new opportunity for sacubitril/valsartan in patients with heart failure and preserved ejection fraction?
Authors: Lupón Josep , Santiago-Vacas Evelyn , Cediel Germán , Codina Pau , Domingo Mar , Revuelta-López Elena , Zamora Elisabet , Spitaleri Giosafat , Santesmases Javier , Núñez Julio , Bayes-Genis Antoni 
Published: May 2021

BackgroundCirculating Neprilysin (sNEP) has emerged as a potential prognostic biomarker in heart failure (HF). In PARAGON-HF benefit of sacubitril/valsartan was only observed in patients with left ventricular ejection fraction (LVEF) ≤57%. We aimed to assess the prognostic value of sNEP in outpatients with HF and LVEF >57%, in comparison with patients with LVEF ≤57%.MethodsConsecutive HF outpatients were included from May-2006 to February-2016. The primary endpoint was the composite of all-cause death or HF hospitalization and the main secondary endpoint was the composite of cardiovascular death or HF hospitalization. For the later competing risk methods were used.ResultssNEP was measured in 1428 patients (age 67.7±12.7, 70.3% men, LVEF 35.8% ±14), 144 of which had a LVEF >57%. sNEP levels did not significantly differ between LVEF groups (p = 0.31). During a mean follow-up of 6±3.9 years, the primary endpoint occurred in 979 patients and the secondary composite endpoint in 714 (in 111 and 84 of the 144 patients with LVEF >57%, respectively). sNEP was significantly associated with both composite endpoints. Age- and sex- adjusted Cox regression analyses showed higher hazard ratios for sNEP in patients with LVEF >57%, both for the primary (HR 1.37 [1.16–1.61] vs. 1.04 [0.97–1.11]) and the secondary (HR 1.38 [1.21–1.55] vs. 1.11 [1.04–1.18]) composite endpoints.ConclusionssNEP prognostic value in patients with HF and LVEF >57% outperforms that observed in patients with lower LVEF. Precision medicine using sNEP may identify HF patients with preserved LVEF that may benefit from treatment with sacubitril/valsartan.
Family-centered music therapy—Empowering premature infants and their primary caregivers through music: Results of a pilot study
Authors: Menke Barbara M. , Hass Joachim , Diener Carsten , Pöschl Johannes 
Published: May 2021

Background
In Neonatal Intensive Care Units (NICUs) premature infants are exposed to various acoustic, environmental and emotional stressors which have a negative impact on their development and the mental health of their parents. Family-centred music therapy bears the potential to positively influence these stressors. The few existing studies indicate that interactive live-improvised music therapy interventions both reduce parental stress factors and support preterm infants’ development.

Methods
The present randomized controlled longitudinal study (RCT) with very low and extremely low birth weight infants (born <30+0 weeks of gestation) and their parents analyzed the influence of music therapy on both the physiological development of premature infants and parental stress factors. In addition, possible interrelations between infant development and parental stress were explored. 65 parent-infant-pairs were enrolled in the study. The treatment group received music therapy twice a week from the 21st day of life till discharge from hospital. The control group received treatment as usual.

Results
Compared to the control group, infants in the treatment group showed a 11.1 days shortening of caffeine therapy, 12.1 days shortening of nasogastric/ orogastric tube feed and 15.5 days shortening of hospitalization, on average. While these differences were not statistically significant, a factor-analytical compound measure of all three therapy durations was. From pre-to-post-intervention, parents showed a significant reduction in stress factors. However, there were no differences between control and treatment group. A regression analysis showed links between parental stress factors and physiological development of the infants.

Conclusion
This pilot study suggests that a live-improvised interactive music therapy intervention for extremely and very preterm infants and their parents may have a beneficial effect on the therapy duration needed for premature infants before discharge from hospital is possible. The study identified components of the original physiological variables of the infants as appropriate endpoints and suggested a slight change in study design to capture possible effects of music therapy on infants’ development as well. Further studies should assess both short-term and long-term effects on premature infants as well as on maternal and paternal health outcomes, to determine whether a family-centered music therapy, actually experienced as an added value to developmental care, should be part of routine care at the NICU.
Training and illness characteristics of cross-country skiers transitioning from junior to senior level
Authors: Karlsson Øyvind , Laaksonen Marko S. , McGawley Kerry 
Published: May 2021

Objective
This study aimed to describe the endurance training and incidence of illnesses reported by a group of well-trained cross-country (XC) skiers throughout their transition from junior to senior level.

Methods
Changes in self-reported training and performance, from 31 well-trained XC skiers, were analyzed from the start of the season they turned 16 y until the end of the season they turned 22 y, using linear mixed-effects models. Differences in the incidence of self-reported illness episodes were analyzed using incidence rate ratios, and the relationships between self-reported illness and training volumes were analyzed using linear mixed-effects models in a sub-group of 23 of the skiers.

Results
In total, 145 seasons of training data (including 85,846 h of endurance training) and 109 person-years of illness data (including 380 self-reported illness episodes) were analyzed. The athletes progressively increased their annual endurance training volume from age 16 to 22 y in a linear fashion, from ~ 470 to 730 h. Low- and high-intensity training volumes increased by 51.4 ± 2.4 h·y-1 (p < .001) and 4.9 ± 0.6 h·y-1 (p < .001), respectively. Sport-specific and non-specific training increased by 50.0 ± 2.2 h·y-1 (p < .001) and 4.6 ± 2.0 h·y-1 (p < .001), respectively. The athletes reported a median (range) of 3 (0–8) illness episodes and 17 (0–80) days of illness per year, and there was an inverse relationship between self-reported illness days and annual training volume (-0.046 ± 0.013 d·h-1; p < .001).

Conclusions
This group of well-trained XC skiers increased their endurance training volume in a linear fashion by ~ 55 h annually. This was primarily achieved through an increase in low-intensity and sport-specific training. Furthermore, higher training volumes were associated with a lower number of self-reported illness days.
The prevalence of mental health problems in sub-Saharan adolescents: A systematic review
Authors: Jörns-Presentati Astrid , Napp Ann-Kathrin , Dessauvagie Anja S. , Stein Dan J. , Jonker Deborah , Breet Elsie , Charles Weslin , Swart Renier L. , Lahti Mari , Suliman Sharain , Jansen Ronelle , van den Heuvel Leigh L. , Seedat Soraya , Groen Gunter 
Published: May 2021

Background and purpose
Most research regarding child and adolescent mental health prevention and promotion in low-and middle-income countries is undertaken in high-income countries. This systematic review set out to synthesise findings from epidemiological studies, published between 2008 and 2020, documenting the prevalence of mental health problems in adolescents from across sub-Saharan Africa.

Methods
A systematic search of multiple databases (MEDLINE, PsycINFO, Scopus) and Google Scholar was conducted guided by the Joanna Briggs Institute (JBI) Reviewer’s manual for systematic reviews of observational epidemiological studies. Studies included reported prevalence outcomes for adolescents aged 10–19 using either clinical interviews or standardized questionnaires to assess psychopathology. Clinical samples were excluded.

Results
The search yielded 1 549 records of which 316 studies were assessed for eligibility and 51 met the inclusion criteria. We present a qualitative synthesis of 37 of these 51 included articles. The other 14 studies reporting prevalence rates for adolescents living with HIV are published elsewhere. The prevalence of depression, anxiety disorders, emotional and behavioural difficulties, posttraumatic stress and suicidal behaviour in the general adolescent population and selected at-risk groups in 16 sub-Saharan countries (with a total population of 97 616 adolescents) are reported.
Investigation of visual and physical factors associated with inadequate instillation of eyedrops among patients with glaucoma
Authors: Kashiwagi Kenji , Matsuda Yuji , Ito Yuka , Kawate Hisami , Sakamoto Masako , Obi Shinji , Haro Hirotaka 
Published: May 2021

Purpose
The aim of this study was to investigate the frequency of eyedrop instillation failure and its related physical and visual function factors among glaucoma patients who used hypotensive eyedrops daily.

Subjects and methods
Patients with a history of self-instillation of one or more ocular hypotensive ophthalmic solutions for six or more months were enrolled. Definitions of instillation failure were eyedrop instillation other than on the eye surface; eyedrop contact with eyelashes; eyedrop bottle tip contact with the eyelashes, eye surface or ocular adnexa; or two or more drops instilled with one instillation trial. To clarify factors related to instillation failure, we used visual function tests and investigated cervical spine extension angles during instillation, pinching strength, physical ataxia (evaluated using the Scale for the Assessment and Rating of Ataxia), motor dysfunction of the upper limbs (evaluated using the Disabilities of the Arm, Shoulder and Hand questionnaire), and vision quality (evaluated using the National Eye Institute Visual Function Questionnaire 25).

Results
Of 103 total subjects, 61.2% satisfied the definition of instillation failure. Instillation of the eyedrop other than at the cul-desac (76.2%) was the most frequent reason for failure, followed by contact of the tip of the eyedrop bottle (22.2%) and instillation of the same or more than two eyedrops in a single attempt (11.1%). Advanced age, a shallow cervical spine extension angle, weak pinching strength, poor motor dysfunction of the upper limbs, the degree of ataxia, poor best-corrected visual acuity, and visual field scores were significant risk factors for instillation failure. Vision quality may have some relation to instillation failure.

Conclusion
It is highly recommended that instillation failure be routinely investigated even among patients with adequate experience using eyedrops and that correct therapies are chosen in a patient-based fashion.
Characterization of geographic mobility among participants in facility- and community-based tuberculosis case finding in urban Uganda
Authors: Robsky Katherine O. , Isooba David , Nakasolya Olga , Mukiibi James , Nalutaaya Annet , Kitonsa Peter J. , Kamoga Caleb , Baik Yeonsoo , Kendall Emily A. , Katamba Achilles , Dowdy David W. 
Published: May 2021

Background
International and internal migration are recognized risk factors for tuberculosis (TB). Geographic mobility, including travel for work, education, or personal reasons, may also play a role in TB transmission, but this relationship is poorly defined. We aimed to define geographic mobility among participants in facility- and community-based TB case finding in Kampala, Uganda, and to assess associations between mobility, access to care, and TB disease.

Methods
We included consecutive individuals age ≥15 years diagnosed with TB disease through either routine health facility practices or community-based case finding (consisting of door-to-door testing, venue-based screening, and contact investigation). Each case was matched with one (for community-based enrollment) or two (health facility enrollment) TB-negative controls. We conducted a latent class analysis (LCA) of eight self-reported characteristics to identify and define mobility; we selected the best-fit model using Bayesian Information Criterion. We assessed associations between mobility and TB case status using multivariable conditional logistic regression.

Results
We enrolled 267 cases and 432 controls. Cases were more likely than controls to have been born in Kampala (p<0.001); there was no difference between cases and controls for remaining mobility characteristics. We selected a two-class LCA model; the “mobile” class was perfectly correlated with a single variable: travel (>3 km) from residence ≥2 times per month. Mobility was associated with a 28% reduction in odds of being a TB case (adjusted matched odds ratio 0.72 [95% confidence interval 0.49, 1.06]).

Conclusion
Frequency of out-of-neighborhood travel is an easily measured variable that correlates closely with predicted mobility class membership. Mobility was associated with decreased risk of TB disease; this may be in part due to the higher socioeconomic status of mobile individuals in this population. However, more research is needed to improve assessment of mobility and understand how mobility affects disease risk and transmission.
Perception of Romanian banking system by the beneficiaries of rural development projects
Authors: Feher Andrea , Rujescu Ciprian , Raicov Miroslav , Tiberiu Iancu , Adamov Tabita 
Published: May 2021

European Agricultural Fund for Rural Development of the EU for funding economic activities in the rural area. As the payments for the Community projects are settlement payments (i.e. the payments are settled in installments after being made, the entrepreneurs need forward funding for their investments, and, therefore, the banks play an important role in forwarding the funds for the projects, as well as in co-funding the eligible expenses. This paper analyzes the way in which the beneficiaries of rural development projects perceive the assistance given by the Romanian banking institutions regarding the steps they must make in order to obtain a loan or to benefit of other necessary banking products or services for the implementation of their projects. The research was carried out in Timiș County, between May and September 2016, on a sample of 96 interviewees, beneficiaries of rural development projects by the National Rural Development Programme 2007-2013. The data collection methods consisted of the survey made on the basis of a standardized questionnaire, using the “face-to-face” technique and the data collection interview method using the “face-to-face” interview.
Tourism developments in Recsk-Parád Basin
Authors: Gubacsi Franciska 
Published: May 2021

In the last two decades a lot of settlements in Recsk-Parád Basin developed by the tourism and related services. Even so other villages have completely different image. These disparate advance paths caused large-scale distinctions in life of the settlements. In my recent study I examine tourism developments in Recsk-Parád Basin. I would like to show the importance of the topic during tourism analysis of five settlements. I formulated a few preliminary assumptions. The former industrial settlements were not less able to develop their touristic sector. Due to deteoration of mining and heavy industry, the local tourism has been expanded. Recsk-Parád Basin is located at Northern Hungary, Heves County, Pétervására small region. These settlements have been analyzed: Bodony, Parád, Mátraderecske, Recsk, Sirok. In my study I analyzed the interactions between the settlements, coordinated the economic, touristic, and social aspects. Over and above I made practical and complex analytical surveys (interviews, questionnaire examination, calculations, field trips, overview of professional studies) and data analysis work. Tourism developed in Recsk-Parád Basin. In the last decade there are more touristic programs and events. Taking advantages of tourist attractions resulted growths in finances and number of guests. The most visited settlement is Parád, it has the most guest nights in Recsk-Parád Basin and in the small region too. The former industrial settlements have transit tourism and less income from this sector, but the castle in Sirok is very popular and results more positive returns. According to the tourist accommodation possibilities, two lines can be observed. The commercial accommodations dominated in Parád, while the private or rural hospitality has a bigger role in the other villages. Expansion of service-trade sector can strengthen the position of the settlements. There is special spa and resort area here, which needs more partnership cooperation. Common events can develop the possibilities. However these tourist settlements are in good position, but they located in a marginalized region. It plays a decisive role to stabilize their positions, find new development directions and widen their possibilities.
Factors influencing functional food and food supplement consumption
Authors: Németh Nikolett 
Published: May 2021

Functional foods and food supplements are two of the major classes of nutraceuticals or food-related products that have health benefits, such as improving health and prevention and treatment of disease. The aim of this present study is to introduce the main factors influencing functional food consumptions as well as food supplement consumption, searching for the answers to the following research questions: (1) What factors affect functional food and food supplement consumption and to what extent? (2) What is the most authentic source of information in customers’ decision making? Results of secondary and primary researches suggest that the most important factors in decision making are: experience in earlier consumption, nutrients, quality and price. Food supplements are complex products and therefore, it is difficult for consumers to check the quality of these products at point of purchase; thus food-safety is a major issue for customers when buying food supplements. It can also be concluded that the availability and reliability of the source of information can greatly determine customer’s decision making. The most authentic source of information according to customers’ opinion were the following: health care professionals, sales staff and health-related articles. These variables should be taken into account for marketers and businesses when considering product development or improving communication on nutritional and health benefits of functional food and food supplements.
The examination of humic substances in soils and composts with high organic content with different methods
Authors: Labancz Viktória , Rétháti Gabriella , Makó András , Szegi Tamás 
Published: May 2021

The organic materials, especially the complex structural humic substances are acid-characteristic polymers which are key elements of soils. Despite their relatively small quantity, humic substances have beneficial effects on soil nutrient management, development of optimal soil structure, regulation of soil temperature, and proper water management. The application of the UV-VIS spectrophotometry for describing humic substances in soils and determining of humifical state is nowadays a widespread method. The E4/E6 procedure (which were determined between 465 and 665 nm wavelength) and the Hargitai-method (the extinction of extracts measured between 400 and 750 nm at 9 wavelength) are procedures that have become the general tool for determining the quality of humic matters because of its easy accessibility and smaller need of instrumentations. Nevertheless, their usefulness has been criticized in scientific communities because of the high human error factor and the technical limitations of the simpler spectrophotometric instruments. Nowadays the spreading light scattering photometric examinations using lasers as the Static Light Scattering (SLS) or the Dynamic Light Scattering (DLS) could be a new way of measuring the quality of the humic matters. This study is based on the examination of different quality soil and compost samples which were extracted from different Hungarian sites like Trizs, Szárítópuszta and Csobánc. Additionally, not only the soils and composts were analyzed but also any soil conditioners (biochar, bone charcoal) which were applied and affected their properties. The main goal of the research was to measure the soil and compost samples with the E4/E6 and the Hargitai-method and with also using Zetasizer Nano ZS device that could lead to more detailed results about the weight and the size of the humic molecules. Based on the summarized analytic results the outcomes of the E4/E6 procedure is applicable for drawing relevant conclusion regarding the humic quality of the given sample. On the contrary, the applied Hargitai-method has not proved to be effective. Although the measurement of the molecule’s size and weight with the Zetasizer Nano ZS device has brought out exciting results and displayed similarities with the E4/E6 outcomes, only it’s tendencies proved to be informative because of its methodological background.