bluuebunny/crossref_metadata_2025_split huggingface dataset:
DOMESTIC ANTITUMOR COMPOUND 2-[3-(2-CHLOROETHYL)-3-NITROSOUREIDO]-1,3- PROPANEDIOL (CHLONISOL). ACUTE TOXICITY
Authors: Stukov A. N. , Vershinina S. F. , Kharitonova N. N. , Filatova L. V. , Latipova D. Н. , Tyndyk M. L. , Zmitrichenko Yu. G. , Semenov A. L. , Bespalov V. G. , Semiglazova T. Yu. 
Published: January 2021

2-[3-(2-Chloroethyl)-3-nitrosoureido]-1,3-propanediol (Сhlonisol) is a representative of a separate group of derivatives of the class of nitrosoalkylureas – alkylnitrosoureidopropanediols, which are characterized by high antitumor activity on a wide range of experimental tumors. Chlonisol LD50 in male mice for intravenous administration was 35 mg/kg, intraperitoneal – 39 mg/kg, in female mice – 34 mg/kg and 36 mg/kg, respectively. In rats of males with intraperitoneal administration, LD50 was 30 mg/kg, in rats of females – 32 mg/kg. The maximum tolerated dose in mice, rats, guinea pigs and rabbits was 20 mg/kg. The tolerated dose for dogs was a dose of 2 mg/kg. Myelo-depression was a dose-limiting side effect. Lethal and sublethal doses of Chlonisol caused aplasia of the bone marrow and lymphoid organs, damage to the mucous membrane of the gastrointestinal tract, and dystrophic changes in the myocardium, lungs, liver, kidneys, pancreas, and reproductive organs. In the late stages after intraperitoneal administration of sublethal doses of Chlonisol, chylothorax and chyloperitoneum were found in some rats.
SHRIMP U-Pb ages and REE patterns for zircon from an anatectic Variscan two-mica granite from the Bemposta Migmatite Complex (Central Iberian Zone)
Authors: Martins Fábio , Azevedo M. Rosário , Valle Aguado Beatriz , Gomes Elisa P. , Tassinari Colombo , Nogueira Neto José 
Published: January 2021

ABSTRACT
The Variscan Bemposta Migmatite Complex (BMC) in northern Portugal (Central Iberian Zone) is a NE–SW-trending high-grade metamorphic core complex comprising upper-amphibolite- to lower-granulite-facies metapelites and metagreywackes of Ediacaran-Cambrian age and subordinate Ordovician orthogneisses showing evidence of intense migmatization.
The available petrological data indicate that these rocks attained peak metamorphic conditions at the end of the first Variscan contractional deformation event (D1), followed an isothermal decompression path during D2 crustal extension, and underwent subsequent retrogression during D3 shearing.
The whole BMC complex hosts numerous concordant intrusive bodies (sheets several meters thick) of syn-D2 two-mica granites, genetically linked to the leucosomes, suggesting that the emplacement of these magmas was synchronous with core complex extension.
U-Pb SHRIMP ages obtained from zircons from one of these syn-D2 tabular plutons (the Faia d'Água Alta granite) yielded a crystallization age of 324 ± 3 Ma, providing a good estimate for the age of the D2 anatectic event in the region.
RANCANG BANGUN SISTEM KEAMANAN SEPEDA MOTOR BERBASIS IOT (INTERNET OF THINGS)
Authors: Tri Wibowo Adi , Salamah Irma , Taqwa Ahmad 
Published: January 2021

Sepeda motor merupakan transportasi pribadi yang paling banyak digunakan masyarakat untuk pergi ke tempat yang dekat bahkan jauh sekalipun. Disamping harganya yang tergolong mudah dijangkau, sepeda motor lebih mudah untuk melalui kemacetan dan jalan sempit sekalipun. Sepeda motor seringkali menjadi target pencurian dikarenakan lemahnya pengawasan terhadap kendaraan. Umumnya sepeda motor hanya memiliki keamanan seperti kunci pengaman konvensional, berbeda dengan kendaraan seperti mobil yang memiliki perangkat GPS (Global Positioning System). Pada penelitian ini dibuatlah rancang bangun sistem keamanan sepeda motor yang menggabungkan mikrokontroler dengan aplikasi android. Mikrokontroler yang digunakan adalah Arduino Mega 2560 yang dilengkapi dengan modul GPS, modul SIM900 dan relay. Penerapan teknologi IOT (Internet of Thing) sebagai media yang digunakan untuk komunikasi antara alat dan aplikasi android. Modul GPS akan memberikan koordinat posisi sepeda motor dan ditampilkan pada aplikasi android melalui komunikasi internet menggunakan modul SIM900. Relay dirancang untuk memutus aliran listrik pada mesin kendaraan. Berdasarkan hasil dari rancang bangun ini nantinya dapat diimplementasikan pada sepeda motor untuk dapat mengetahui posisi kendaraan yang telah dicuri.
Application of the refined asymptotic model for describing of the transient extensional edge wave exited by a tangential load applied to the edge
Authors: Белосточный Григорий Николаевич , Вильде Мария Владимировна , Сурова Мария Юрьевна 
Published: January 2021

Изучается возможность применения уточненной асимптотической модели планарной краевой волны в задаче о действии нестационарной касательной нагрузки, приложенной на торце. При построении уточненной модели используется асимптотическая двумерная теория растяжения пластин высшего порядка точности. Приводятся результаты сравнения с решением по трехмерной теории упругости для различных законов распределения нагрузки. Показано, что уточненная модель позволяет достаточно точно описать влияние дисперсии краевой волны, не учитываемое в первом приближении.
The possibility of application of the refined explicit model for extensional edge wave in the problem of transient waves excitation by an edge tangential load is investigated. The refined model is based on the higher order theory of plate extension. The results of comparison with the 3D solution for various distributions of the load are presented. It is shown that the refined model allows correct describing of dispersion effects which are not taken into account in the leading approximation.
Mathematical modeling of transfer intensive of edges of spatial cracks on the fronts of longitudinal and shear waves by a ray method
Authors: Быкова Мария Игоревна , Вервейко Николай Дмитриевич , Крупенко Светлана Евгеньевна , Шашкин Александр Иванович , Шашкина Софья Александровна 
Published: January 2021

В ближайшей окрестности вершины плоской трещины, а в общем случае, вблизи передней кромки пространственной трещины, деформирование материала носит неупругий характер. В работе предложено лучевое моделирование высокоскоростного деформирования материала в δ-окрестности подвижной передней кромки трещины, используя динамическую упруговязкопластическую модель тела Бингама с условием пластичности Мизеса. Показано, что распространяющаяся передняя кромка трещины продольного сдвига лежит на поверхности сильного разрыва продольной скорости, бегущей со скоростью упругих продольных волн, а передняя кромка трещины отрыва и трещины поперечного сдвига лежит на поверхности сдвиговой волны, бегущей со скоростью волн сдвига. Введены интенсивности передних кромок трещин: скачок скорости сдвига поперек передней кромки трещины продольного сдвига, скачок поперечной скорости на передней кромке трещины отрыва, скачок касательной скорости к передней кромке трещины поперечного сдвига. Построены обыкновенные дифференциальные уравнения переноса интенсивностей передних кромок трещин вдоль лучей как ортогональных траекторий точек переднего фронта. Получены приближенные решения уравнений переноса интенсивностей передних кромок пространственных трещин в напряженный материал и приведены выражения для глубины проникания пространственных трещин. Показано изменение направления сдвига и отрыва в передних кромках соответствующих трещин в зависимости от напряженного состояния перед трещинами. Приведены графики численных расчетов переноса интенсивностей передних кромок трещин и глубины их проникания.
In the near neighborhood of the top of the plane crack, and in General, in the space case, near the edge of the spatial crack, the deformations of the material have the inelastic character. In this article proposes the elasticviscoplastic model of the Bingham body with the condition of plasticity of Mises for modeling high velocity deformation material near of the top of crack. Shown that an edge of crack belong a surface of elastic wave: cracks of longitudinal shear belong of longitudinal wave and a crack of untiplane shear and avulsion belong a surface of shear wave. For intensity of the crack suggest a shock velocity on the curve of the edge of crack and made ordinary differential equation for transfer intensity of crack on the front of the wave. Shown that a distant of propagation edge of the crack depend from plastic deformation material on the front of the wave. In the process of propagation crack this direction of shear can change from a stresses in front of the wave. Three-D graphics show change intensity of the crack in a process of propagation from parameters.
Biaxial tension of a thin plate made of elastoplastic material under the condition of resistance to separation
Authors: Матвеев Сергей Владимирович , Матвеева Алёна Николаевна 
Published: January 2021

В работе рассматривается задача определения компонент напряжения при двуосном растяжении тонкой пластины из упругопластического материала. Пластина ослаблена круговым отверстием. В задаче рассматривается случай сопротивления отрыву, σ1 = σ2 = p, σ3 < p, p = const. Решение ищется методом разложения по малому параметру, аналогично работам [1-4]. В работе были получены выражения для определения компонент напряжения в упругой и пластической областях в первом приближении.
The paper considers the problem of determining the stress components during biaxial tension of a thin plate made of elastoplastic material. The plate is weakened by the circular hole. The problem considers the case of separation resistance, σ = σ = p , σ < p , p = const . The solution is sought by the method of decomposition in a small parameter, similar to the works of [1-4]. In this work, expressions were obtained for determining the stress components in the elastic and plastic regions in the first approximation.
Autoconocimiento y autoeficacia en grupos de tercera edad. Región de Salud de Panamá Oeste. Panamá.
Authors: Lopez Sinisterra Lourdes Gabriela , De López Aracelly 
Published: January 2021

Introducción: en Panamá, se ha incrementado la población de tercera edad, lo que ha generado transformaciones en salud y seguridad social del país.Objetivo: analizar el autoconocimiento y autoeficacia en la población de tercera edad de los grupos organizados en la Región de Salud de Panamá Oeste.Materiales y Métodos: Estudio descriptivo transversal. Fueron aplicadas la metodología de grupo focal, encuestas psicosociales de salud estructuradas y frecuencia de consumo de alimentos protectores y de riesgo, en una muestra no probabilística de 117 adultos mayores de 11 centros de salud.Resultados: se abordó el 100% de los grupos organizados, la edad promedio fue de 69 años, el 76% fueron mujeres y el 24 % hombres. El 97% realizó control de salud y reportaron padecer de enfermedades crónicas. El 95% está satisfecho con lo alcanzado en su vida, el 50% manifestó tener ingresos de 1 a 300 Balboas y el 33% de los entrevistados cursó primaria completa.De acuerdo al consumo de alimentos, se identificó un alto consumo de alimentos de riesgo para enfermedades crónicas como: azúcares por el 72% y el consumo de sal por el 60 %.
Conclusión: Los factores psico-sociales y los hábitos de alimentación, influyen en la calidad de vida y longevidad, por tanto, la autoeficacia y el autoconocimiento son fortalecidos al pertenecer a un grupo organizado. El conocimiento generado facilita la revaloración de las actividades dirigidas a promover la salud y calidad de vida en la población de la tercera edad.
Estresores vinculados a la infertilidad en mujeres y hombres que inician un tratamiento de reproducción asistida en la Clínica de la Pareja Infértil del Departamento de Investigación en Salud Sexual y Reproductiva
Authors: Flores Castro Heydeé , Mendoza Alba , Martinez Ligia , González Itzi , De León Ruth 
Published: January 2021

Introducción: La Organización Mundial de la Salud señala que el 8% de las parejas en todo el mundo tienen problemas para concebir hijos. Diversas investigaciones señalan que las parejas que enfrentan la infertilidad presentan alteraciones psicológicas como ansiedad elevada, frustración, ira, pérdida de autoestima y estrés, entre otros. El objetivo general: determinar algunos estresores vinculados a la infertilidad en un grupo de mujeres y sus parejas que buscan tratamiento de reproducción asistida, con el propósito de tener una caracterización de esta población y poder contribuir a la implementación de un abordaje integral multidisciplinario. Materiales y Método: estudio descriptivo observacional realizado en la Clínica de la Pareja Infértil del Instituto Conmemorativo Gorgas de Estudios de la Salud. Se utilizó un muestreo por conveniencia basado en el número de consultas médicas del año anterior al estudio. Se aplicó el Inventario sobre Problemas de Fertilidad. Para el análisis estadístico, se utilizó el programa Epi Info versión 7.2. Resultados: se estudió un total de 427 personas: 297 mujeres y 130 varones entre las edades de 20 a 51 años. El estrés global asociado a la infertilidad presenta un puntaje medio de 146.08 con una desviación estándar de 27.70, las mujeres tienen un estrés promedio de 148.15 y los hombres de 141.34, estas diferencias son estadísticamente significativas. De las 5 escalas que mide la prueba solo dos de ellas presentaron diferencias estadísticamente significativas: “Preocupaciones Sociales” y “Preocupaciones Sexuales”. Conclusión: La mayoría de los participantes presentan un Estrés General ligado a la infertilidad moderadamente alto.
Sadayakko és Hanako Budapesten
Authors: Doma Petra 
Published: January 2021

In the beginning of the 20th century, two celebrated Japanese actresses, Kawakami Sadayakko (1871–1946) and Hanako (1868–1945), visited Budapest. Sadayakko, accompanied by the Kawakami troupe, arrived in February 1902 and performed at the Uránia Theatre. Hanako visited the Hungarian capital twice: in 1908 and 1913. Both of them played in ‘Japanese-style’ performances, which at first seemed traditional and authentic to the Hungarian audience. The most important and spectacular element of these plays was the death scene and the supernatural way the actresses performed this on stage. In the present paper I analyse various kinds of contemporary articles and examine how the two actresses appeared in and influenced Hungarian theatre history. Additionally, through the analysis of the press of the times, I will argue that Hanako’s second visit was less successful than her first or than Sadayakko’s, and show that the audience’s opinion about the authenticity of the performance changed completely.
Future Directions in Japanese Studies in Central and Eastern Europe
Authors: Zentai Judit Éva 
Published: January 2021

Selected Essays from the 2018 PhD Workshop in Budapest (A közép- és kelet-európai japán tanulmányok jövőbeli irányai – Válogatás a 2018-ban Budapesten megrendezett PhD Műhelysorozat résztvevőinek írásaiból) Szerkesztette: Papp Melinda Institute for East Asian Studies, Eötvös Loránd University, Budapest, 2019
A Dhammacakkappavattana-sutta egyik korai kínai fordítása
Authors: Kósa Gábor 
Published: January 2021

In this paper I offer the Hungarian translation and commentary of a rather early Chinese translation of the Dhammacakkappavattana-sutta (‘Setting the Wheel of Dhamma in Motion’), one of the most important Buddhist suttas recounting the first sermon of the historical Buddha. This Chinese translation (T02n109: Fo shuo zhuan falun jing 佛說轉法輪經), slightly neglected in previous research, is traditionally attributed to An Shigao 安世高 (2nd c. AD), but I argue that, based on the terminological similarities between this scripture and the Zhong benqi jing 中本起經 (T196), Kang Mengxiang 康孟詳 (ca. 200 AD) would be a more plausible candidate for the authorship.
Az irodalmi többnyelvűség stilisztikai megjelenése Domonkos István: Kormányeltörésben és Tawada Yōko: A követ című műveiben
Authors: Tóth Julianna Nikolett 
Published: January 2021

Multilingualism in literature is a well-known and extensively studied phenomenon. Due to the effects of globalization, however, a new complex form of multilingualism has emerged among writers, which can be studied as a linguistically and culturally hybrid literary form. This linguistic hybridity is called exophony. This paper aims to conduct deeper research into this fairly new literary expression and its usage in contemporary literary criticism. First, we examine the etymology, meaning, and usage of exophony, then we analyze its effects on poetic language. The second part of this paper provides some concrete example of exophony as a stylistic device in Yōko Tawada’s The Emissary (献灯使, Kentōshi) and István Domonkos’s Rudderless (Kormányeltörésben). The study finds that – although Japanese and Hungarian have different writing and linguistic systems, and have very few common points in their literary traditions, – exophony shows more or less the same characteristics in both works. This finding provides additional ways to use exophony as a concept in literary discourses.
Susceptibility of multidrug-resistant nosocomial pathogens for the new antimicrobial agents in Jordan
Authors: Wadi Al Ramahi M.D, FIDSA Jamal , Said MaramAbu , Kwaik Rasmieh Abu , Jamal Walid , Jammal Deema Al , Radaidah Nisreen Al , Aqel Amin A. 
Published: January 2021

Background
To study resistance rates of multidrug-resistant bacteria (MDR) for new Cephalosporines before their widespread use in Jordan.
Methods
During September 2019 - May 2020, MDR-bacteria were prospectively collected from microbiology laboratories of three hospitals, susceptibility of the extended-spectrum β-lactamases-producing Enterobacteriaceae (ESBL), K. pneumoniae-carbapenemases strains (KPC), carbapenem-resistant Enterobacteriaceae (CRE), carbapenem-resistant P. aeruginosa (CRPa), carbapenem-resistant A. baumannii (CRAb), and Methicillin-resistant Staphylococcus aureus (MRSA) were tested. Demographic details for patients were identified. Antimicrobials evaluated were ceftazidime-avibactam, ceftolozane-tazobactam, and ceftobiprole medocaril.
Results
Non-duplicate 263 MDR clinical isolates were collected from sterile sites; ESBL (128), P. aeruginosa (57), MRSA (37), KPC (22), A. baumannii (11), and CRE (n = 8). The age was dominated by the older age group (Age > 64, Pearson R = 0.985, R2 = 0.969, P = 0.000). Males were 143 and females 107 (P < 0.000). There were (194) isolate from the wards and (55) were from the ICUs. Sources were urine (96), blood (36), soft tissues (49), abdomen (24), URT (14), and osteo-skeletal (12). Clinical diagnoses were: UTI (90). Bacteremia (36), SSTI (45), IAI (23), pneumonia (17), URTI (13), osteomyelitis (11), and diabetic foot (6). The susceptibility of the ESBL-producing bacteria was 100% for meropenem, 99% for ceftazidime-avibactam, and 90% for ceftolozane/tazobactam. P. aeruginosa was, 73% for ceftazidime-avibactam, 62% susceptible to ceftolozane/tazobactam, 62% for meropenem, and 45% to ceftobiprole. CRE was 38% susceptible to ceftazidime-avibactam and KPC 15%, while ceftolozane-tazobactam susceptibility was zero, and 14% for CRE, and 0% for Ceftobiprole Medocaril. A. baumannii was 13% susceptible to ceftazidime-avibactam, meropenem 9%, and 2% for ceftolozane/tazobactam
Conclusion
Ceftazidime-avibactam and ceftolozane/tazobactam may be useful alternatives for the treatment of ESBL-producers and P. aeruginosa, though the MDR-bacteria demonstrated some resistance to the newly introduced agents before their widespread use in the country.
Dust Production from Mini Outbursts of Comet 29P/Schwassmann-Wachmann 1
Authors: Clements Tiffany D. , Fernandez Yanga 
Published: January 2021

Abstract
Here we report on the results of observations of comet 29P/Schwassmann-Wachmann 1 obtained using four telescopes, in three different countries, from 2019 September 25 to 2020 January 19. During the last four months of 2019, comet 29P/Schwassmann-Wachmann 1 exhibited new outburst behavior indicative of small or mini outbursts in which the brightening of the comet lasted from only a few days to more than a week. We used Johnson-Cousins R
C-band multi-aperture photometry measurements to calculate the dust production, via Afρ, the dust production rate, and the dust brightness profile of the comet for each night of observations. During these observations, the brightness of the comet fluctuated significantly multiple times, with notable changes in brightness ranging from 0.41 to 0.71 mag over time periods of only a couple of days to nearly two weeks.
Analyse de l’efficience des écoles primaires sénégalaises à partir de la méthode des frontières stochastiques
Authors: Wassongma Harouna , Seck Fall François 
Published: January 2021

L’objet de cette étude est de mettre en évidence le rôle déterminant des conditions d’apprentissage scolaire sur la performance des élèves. Nous appliquons la méthode des frontières stochastiques à un échantillon de 151 écoles primaires du Sénégal. Les résultats mettent en évidence une inefficience des écoles primaires, avec un score d’efficience technique de 86,01 %. Ils montrent aussi le rôle déterminant des facteurs intra-scolaires dans l’efficience de l’élève. Le taux d’absentéisme des enseignants, le salaire de l’enseignant, les retards de paiement expliquent significativement l’inefficience de l’élève. Le niveau de l’enseignant et son expérience déterminent significativement la performance scolaire. Il ressort également que les conditions matérielles d’apprentissage dans l’école et la classe sont déterminantes pour la performance scolaire. L’infrastructure de base de l’école et le ratio manuel/élève affectent significativement la performance scolaire. Toutefois, certaines variables comme le ratio manuel/élève et l’âge (expérience) de l’enseignant sont marquées par des effets de seuil. Codes JEL : C13, D61, H52, I21.
Les rapports à l’école comme rapports à l’État
Authors: Barrault-Stella Lorenzo , Bongrand Philippe , Hugrée Cédric , Siblot Yasmine 
Published: January 2021

En France, plusieurs traditions de recherche ont étudié le système scolaire, son essor, et plus particulièrement les inégalités sociales de scolarisation et leurs conséquences en matière de différenciation sociale et symbolique des groupes sociaux. Mais ces études se préoccupent rarement d’examiner comment les rapports à l’école participent de rapports plus larges aux institutions publiques. Ces interrogations n’ont pas non plus été au cœur des recherches sur l’État : les analyses des politiques scolaires ne mettent pas à l’épreuve l’hypothèse de la dimension étatique des rapports à l’école des parents et élèves. Enfin, les recherches consacrées aux rapports « ordinaires » aux institutions, si elles accordent une place déterminante aux ressources scolaires et culturelles, interrogent rarement la portée des pratiques et des représentations liées à la scolarisation sur les rapports à d’autres institutions. Ce dossier entend contribuer à ces questionnements en proposant d’étudier l’école sans oublier l’État et, réciproquement, d’interroger la portée de l’école lorsqu’on enquête sur l’État. L’enjeu plus général de ce dossier est ainsi de placer la socialisation à l’État et les usages sociaux des institutions publiques au cœur de l’analyse des rapports à l’école, pour saisir de quelle manière sont déterminés, construits et façonnés les rapports à l’ordre étatique, aux diverses institutions administratives et politiques qui composent l’État.