bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of auriculotherapy for postoperative nausea and vomiting: A systematic review protocol
Authors: Santos Isabella Boechat Faria , Silva Amanda Suzane Alves da , Melo Giovana Salomão , Soares Cleuma Oliveira , de Andrade Edila Monteiro , Rodrigues Lúcio Flávio Garcia , Mendonça Thalia Saraiva , Dantas Diego Bessa , de Melo-Neto João Simão 
Published: November 2021

Abstract
Background
Postoperative nausea and vomiting (PONV) is a distressing complication of anesthesia and can lead to aspiration, dehydration, and electrolyte imbalance. Antiemetic agents are conventionally prescribed to manage PONV; however, they have associated side effects. Therefore, unconventional methods, such as auricular acupuncture (AA), are also utilized to prevent and control emesis after surgery. AA originated in traditional Chinese medicine and is based on a diagnostic and treatment system that aims to normalize dysfunction through stimulation of reflex points on the ear. The aim of this study is to evaluate the effects of AA in controlling PONV.
Methods
We will perform a systematic review according to the Cochrane methodology. An overall search strategy will be developed and adapted for PubMed, PEDro, the Virtual Health Library, SciELO, EMBASE, the Web of Science, SciVerse Scopus, and the Cochrane Library to search for the following descriptors: “Acupressure”; “Antiemetics”; “Postoperative nausea and vomiting”; “Surgery”; “Auriculotherapy”; “Nausea”; “Vomiting”; and “Postoperative period.” Articles with a mean score of 6 ± 1.5 on the PEDro scale will be evaluated. The size of the intervention effect (Z) will be calculated for each outcome included in this review. The primary outcome will be the incidence of PONV. The secondary outcome will be the severity of PONV. Quality assessment will be performed with the Cochrane instrument. If possible, a meta-analysis will be performed using Review Manager 5.3 software.
Discussion
Several studies have reported positive outcomes of AA for patients with PONV. This study could provide robust and conclusive evidence of the usefulness of AA as an effective treatment alternative for emesis without the side effects of conventional medication.
Trial registration
Systematic review registration number: CRD42020149772 (S1 File)
Prevalence and Correlates of Current Tobacco use and Non-user Susceptibility to using Tobacco Product Among School-going Adolescents in 22 African Countries, 2013-2018
Authors: James Peter Bai , Bah Abdulai Jawo , Kabba John Alimamy , Kassim Said Abasse , Dalinjong Philip Ayizem 
Published: November 2021

Abstract
Background Our study examined the prevalence and associated factors of tobacco product use and non-users’ susceptibility to using tobacco products among school-going adolescents in 22 African countries.MethodsWe analysed the cross-sectional 2013-2018 GYTS data from 22 African countries. We conducted complex sampling descriptive and logistic regression analyses. We reported our results using frequencies and proportions for descriptive statistics and adjusted odd ratios and 95% confidence intervals for logistic model.ResultsThe overall prevalence of current use of any tobacco product among adolescents was 19.1%, with more males (23.7%) than females (13.7%) being current users. Zimbabwe and Morocco were the highest (47.1%) and least (12.6%) reported prevalence respectively. Being male (AOR=1.930;95%CI:1.614-2.307), exposure to secondhand smoke within (AOR=2.069;95%CI:1.763-2.429) and outside (AOR=1.364;95%CI:1.138-1.635) the home, not knowledgeable about the harmful effect of secondhand smoke (AOR=1.413;95%CI:1.178-1.693), exposure to tobacco industry promotion (AOR=3.027;95%CI:2.653-3.453) and not in favour of banning smoking in enclosed places (AOR=1.222;95%CI:1.014-1.472) were associated with current use of any tobacco product. The prevalence of the susceptibility to using tobacco products among never users of tobacco products was 12.2%, with no significant gender difference. Mozambique (24.6%) and Algeria (4.5%) had the highest and least prevalence of the susceptibility to using tobacco products among never users, respectively. Exposure to tobacco industry promotion (AOR=1.730;95%CI:1.485-2.015) and those not in favour of banning smoking in enclosed places (AOR= 1.323;95%CI:1.142-1.532) were associated with susceptibility to using any tobacco product among never users of tobacco products.ConclusionOur study reports that tobacco use and non-user susceptibility to using tobacco product among school-going adolescents in the 22 African countries is high. As part of public health efforts, governments and other stakeholders need to fully implement anti-tobacco use campaigns, enforce a complete ban on tobacco promotion and advertising, institute educational programs for families, and anti-tobacco use education for the general public and in schools in line with WHO Framework Convention on Tobacco Control guidelines.
“It’s a sign of weakness:” Masculinity, Help-Seeking Behaviors, and Gender-Specific Experiences Accessing VA PTSD Care
Authors: Silvestrini Molly , Chen Jessica A. 
Published: November 2021

Abstract
Background: Male veterans delay post-traumatic stress disorder (PTSD) treatment and are less likely to engage in help-seeking behaviors or receive adequate mental health treatment. Male veterans face additional stigma seeking mental health care due to traditional masculine ideologies perpetuated by military culture. This study presents the gender-specific perspectives of veterans accessing VA PTSD care, focusing particularly on the help-seeking behaviors and barriers to care experienced by male veterans. Methods: Semi-structured interviews were conducted with 25 U.S. veterans seeking treatment in VA primary care. Qualitative data analysis was coded using Atlas.ti, and thematic analysis was used to develop and refine themes. This study is part of a larger study examining veterans’ initiation of PTSD treatment. Results: Findings indicate that male veterans may be reluctant to initiate PTSD care due to stigma, distrust of the military or mental health care, and a desire to avoid reliving their trauma. Social support may encourage help-seeking behaviors among this population. Both male and female veterans reported a need for non-combat PTSD care and resources for military sexual trauma (MST). Conclusions: Findings indicate that male veterans face unique challenges accessing mental health services and PTSD treatment, while both male and female veterans may benefit from increased VA services focused on MST and non-combat specific PTSD.
Pyroptosis-related Prognosis Model, Immunocyte Infiltration Characterization, and Competing Endogenous RNA Network of Glioblastoma
Authors: Ding Min-Rui , Qu Yan-Jie , Peng Xiao , Chen Jin-Fang , Zhang Meng-Xue , Zhang Tong , HU BING , An Hong-Mei 
Published: November 2021

Abstract
Background: Glioblastoma (GBM) has a high incidence rate, invasive growth, and easy recurrence, and the current therapeutic effect is less than satisfying. Pyroptosis plays an important role in morbidity and progress of GBM. Meanwhile, the tumor microenvironment (TME) is involved in the progress and treatment tolerance of GBM. In the present study, we analyzed prognosis model, immunocyte infiltration characterization, and competing endogenous RNA (ceRNA) network of GBM on the basis of pyroptosis-related genes (PRGs).Methods: The transcriptome and clinical data of 155 patients with GBM and 120 normal subjects were obtained from The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression (GTEx). Lasso (Least absolute shrinkage and selection operator) Cox expression analysis was used in predicting prognostic markers, and its predictive ability was tested using a nomogram. A prognostic risk score formula was constructed, and CIBERSORT, ssGSEA algorithm, Tumor IMmune Estimation Resource (TIMER), and TISIDB database were used in evaluating the immunocyte infiltration characterization and tumor immune response of differential risk samples. A ceRNA network was constructed with Starbase, mirtarbase, and lncbase, and the mechanism of this regulatory axis was explored using Gene Set Enrichment Analysis (GSEA). Results: Five PRGs (CASP3, NLRP2, TP63, GZMB, and CASP9) were identified as the independent prognostic biomarkers of GBM. Prognostic risk score formula analysis showed that the low-risk group had obvious survival advantage compared with the high-risk group, and significant differences in immunocyte infiltration and immune related function score were found. In addition, a ceRNA network of messenger RNA (CASP3, TP63)–microRNA (hsa-miR-519c-5p)–long noncoding RNA (GABPB1-AS1) was established. GSEA analysis showed that the regulatory axis played a considerable role in the extracellular matrix (ECM) and immune inflammatory response.Conclusions: Pyroptosis and TME-related independent prognostic markers were screened in this study, and a prognosis risk score formula was established for the first time according to the prognosis PRGs. TME immunocyte infiltration characterization and immune response were assessed using ssGSEA, CIBERSORT algorithm, TIMER, and TISIDB database. Besides a ceRNA network was built up. This study not only laid foundations for further exploring pyroptosis and TME in improving prognosis of GBM, but also provided a new idea for more effective guidance on clinical immunotherapy to patients and developing new immunotherapeutic drugs.
Comparing Two Different Automatic Methods to Measure Femoral Neck-Shaft Angle Based on PointNet++ Network
Authors: Li Zhe , Yang Jiayu , Li Xinghua , Wang Kunzheng , Han Jungang , Yang Pei 
Published: November 2021

Abstract
Bacnground:
Accurate measurement of the femoral neck-shaft angle (NSA) is of great significance for diagnosing hip joint diseases and preoperative planning of total hip arthroplasty. However, the fitting lines of the femoral neck and femoral shaft did not always intersect in 3D space. Thus, it is unclear whether there is a difference between 2D and 3D methods for measuring NSA.
Methods:
The femoral point cloud datasets from 310 subjects were segmented into three regions, including the femoral head, femoral neck, and femoral shaft using PointNet++. We created a projection plane to simulate the hip anteroposterior radiograph and fitted the femoral neck axis and femoral shaft axis to complete the 2D measurement, while we directly fitted the two axes in space to complete the 3D measurement. Also, we conducted the manual measurement of the NSA. We verified the accuracy of the segmentation and compared the results of the two automatic and manual methods.
Results:
The Dice coefficient of femoral segmentation reached 0.9746, and MIoU of that was 0.9165. No significant difference was found between any two of the three methods. While comparing the 2D and 3D methods, the average accuracy was 98.00%, and the average error was 2.58°.
Conclusion:
This paper proposed two accurate and automatic methods to measure the NSA based on a 2D plane and a 3D model respectively. Although the femoral neck and femoral shaft axes did not intersect in 3D space, the NSAs obtained by 2D and 3D methods were basically consistent.
Bicycle Industry As a Post-pandemic Green Recovery Driver in an Emerging Economy: A SWOT Analysis
Authors: Xames Doulotuzzaman , Shefa Jannatul , Sarwar Ferdous 
Published: November 2021

Abstract
The COVID-19 pandemic has exposed socioeconomic vulnerabilities around the world. After fighting the coronavirus for more than one and a half years now, the countries are recovering from the epidemic with the help of cutting-edge medical research. The policymakers are implementing stimulus packages for post-pandemic economic recovery. However, sustainable ‘green recovery’ plans are yet to get adequate attention. Sustainable investment in green industries can create green jobs, promote a low-carbon economy, and foster long-lasting economic growth in the post-pandemic world. The COVID-19 affected countries with emerging economies call for even more focus on such investments. In Bangladesh, the bicycle industry - a growing low-carbon industry – has been showing promising potential for growth since the beginning of the pandemic. Both the local and global markets of Bangladeshi bicycles have seen substantial growth during the epidemic. In this paper, we analyze the potential of the Bangladeshi bicycle industry as an effective green recovery driver. We conduct semi-structured interviews with relevant experts and professionals, analyze their opinions, and perform a ‘strengths, weaknesses, opportunities, and threats (SWOT)’ analysis. The analysis reveals valuable insights regarding post-pandemic sustainable economic and environmental recovery which will be beneficial to the policymakers of Bangladesh and similar developing countries.
Hydrothermally synthesized Nickel cobalt oxide for bifunctional electrochemical supercapacitor and nonenzymatic glucose biosensor
Authors: Pore O. C. , Fulari A. V. , Fulari V. J. , Lohar G. M. 
Published: November 2021

Abstract
Herein, various nickel cobalt oxide nanostructures with different Ni concentrations are prepared via hydrothermal route and then calcination process for electrochemical supercapacitor as well as nonenzymatic glucose biosensor. The electrode synthesized on carbon cloth using Ni0.9Co2.1O4 nanosheet-like morphology showed a maximum 516.51 F g−1 specific capacitance at 10 mV s−1 scan rate and the cyclic stability of 87.7% over 2000 GCD cycles. The electrode prepared with Ni0.3Co2.7O4 on CC offered a linear response from 0 to 0.3 mM glucose concentration and exhibited a maximum of 759.5 µA mM−1 cm−2 glucose sensitivity.
Personality traits in post-COVID syndrome
Authors: Delgado-Alonso Cristina , Valles-Salgado María , Delgado-Álvarez Alfonso , Gómez-Ruiz Natividad , Yus Miguel , Polidura Carmen , Pérez-Izquierdo Carlos , Marcos Alberto , Gil María José , Matías-Guiu Jorge , Matias-Guiu Jordi A 
Published: November 2021

Abstract
Background. We aimed to evaluate personality traits in patients with postCOVID syndrome, as well as the association with neuropsychiatric symptoms present in this disorder. Methods. The Big Five Structure Inventory was administered to 93 consecutive patients with a diagnosis of post-COVID syndrome and to matched controls. We also performed a comprehensive evaluation of depression, anxiety, fatigue, sleep quality, cognitive function, and olfactory function. Results. Patients with post-COVID syndrome scored lower for emotional stability, equanimity, positive mood, and self-control. Extraversion, emotional stability, and openness correlated negatively with anxiety and depression levels. Conscientiousness correlated negatively with anxiety. No statistically significant correlations were observed between personality traits and cognitive function, sleep quality, olfactory function, or fatigue. Personality scores explained 36.3% and 41% of the variance in scores on the anxiety and depression scales, respectively. Two personality profiles with lower levels of emotional stability were associated with depression and anxiety. Conclusions. Our study shows higher levels of neuroticism in patients with post-COVID syndrome. Personality traits were predictive of the presence of depression and anxiety, but not cognitive function, sleep quality, or fatigue, in the context of post-COVID syndrome. These findings may have implications for the detection of patients at risk of depression and anxiety in post-COVID syndrome, and for the development of preventive and therapeutic interventions.
Exploring alternative insecticide delivery options in a “Lethal House Lure” for malaria vector control
Authors: Oumbouke Welbeck A. , Barreaux Antoine M.G. , Zran Innocent T. , Koffi Alphonsine A. , N’Guessan Yao , Alou Ludovic P. Ahoua , Wolie Rosine Z. , Cook Jackie , Sternberg Eleanore D. , Thomas Matthew B. , N’Guessan Raphael 
Published: November 2021

Abstract
The In2Care® EaveTube is a house modification designed to block and kill malaria mosquitoes using an electrostatic netting treated with insecticide powder. A previous study demonstrated prolonged duration of effective action of insecticide-treated electrostatic netting in a semi-field setting. As part of a cluster randomized controlled trial (CRT) of the EaveTube intervention in Cote d’Ivoire, we investigated the residual efficacy of a pyrethroid insecticide deployed in Eave Tubes under village condition of use. We also explored the scope of using existing malaria control technologies including LLINs and IRS as alternative methods to deliver insecticides in the lethal house lure. The efficacy of beta-cyfluthrin was evaluated using the “eave tube bioassay” and was found to be relatively short-lived in the field during the CRT, with mortality of pyrethroid resistant Anopheles gambiae mosquitoes declining below 80% after 4 months. The impact (mosquito mortality) of PVC tubes coated with pirimiphos methyl was similar to that of beta-cyfluthrin treated insert (66.8 vs 62.8%) in release-recapture experiments in experimental huts. Efficacy was significantly lower with all the LLINs tested; however, the roof of PermaNet 3.0 induced significantly higher mosquito mortality (50.4%) compared to Olyset Plus (25.9%) and Interceptor G2 (21.6%) LLINs. The new delivery methods showed a rapid decline in efficacy over time with mortality decreasing below 50% within 2 months in residual activity bioassays. None of the current products appeared superior to the powder treatments but as with the powders, further research and development on formulations and doses are required.
Resection or Preservation? A Tough Surgical Decision for Chinese Breast Cancer Patients Who are in Line with Breast Conserving
Authors: Zhu Pingting , Ji Qiaoying , Liu Xinyi , Xu Ting , Wu Qiwei , Wang Yuejuan 
Published: November 2021

Abstract
Purpose

Breast cancer patients who are in line with breast conserving are faced more challenges in making surgery decision, because breast conservation and mastectomy have equivalent oncologic outcomes. The purpose of this study is to analyze the surgical decision-making process for breast cancer patients and further explore the reasons why do Chinese women who are in line with breast conserving are more likely to choose mastectomy.
Methods

A qualitative study was conducted. With the sample saturation principle, data collected by semi-structured interviews with 24 breast cancer patients who are in line with breast conserving. Colaizzi’s method of phenomenology was used for data analysis.
Results

Three major themes emerged from the data. The themes were the following: (1) lack of significant decision-making support (stereotyping of breast cancer surgery, inferior quality of interaction with health professions, and without the help of decision aids); (2) can’t mull under the strike (immediacy of the decision, breasts are out of deliberating, and escape); and (3) edified by the Chinese culture (deep family values, hiding concerns about femininity, and conservative character).
Conclusions

Our findings explore the reasons why more Chinese breast cancer patients with breast conserving conditions choose mastectomy, and help patients to choose knowledge-based treatment options which are concordant with their needs, values, and preferences.
Synbiotic Supplementation Modulates Gut Microbiota, Regulates Beta-Catenin Expression And Prevents Weight Gain in ob/ob Mice
Authors: Duarte Sebastião Mauro Bezerra , Stefano José Tadeu , Franco Lucas A. M. , Martins Roberta C. , Moraes Bruna D. G. C. , Barbeiro Denise Frediani , Oliveira Nathalia , Neri Junia Marielle Teixeira Rodrigues , Vanni Denise Siqueira , Sabino Ester C. , Carrilho Flair José , Oliveira Claudia P. 
Published: November 2021

Abstract
Background: The aim of this study was to examine the impact of synbiotic supplementation in obesity and microbiota in ob/ob mice. 20 animals were divided into four groups: Obese Treated (OT), Control (OC), Lean Treated (LT) and Control (LC). All animals received standard diet for 8 weeks. Treated groups received a synbiotic in water while nontreated groups received water. After 8 weeks, all animals were sacrificed and gut tissue mRNA isolation and stool samples by microbiota analysis were collected. Beta-catenin, occludin, cadherin and zonulin were analyzed in gut tissue by RT-qPCR. Results: The synbiotic supplementation reduced body weight gain in OT comparing with OC (p=0.0398), increase of Enterobacteriaceae (p=0.005) and decrease of Cyanobacteria (p=0.047), Clostridiaceae (p=0.026), Turicibacterales (p=0.005) and Coprococcus (p=0.047). A significant reduction of Sutterella bacteria (p=0.009) and Turicibacter (p=0.005) was observed in LT compared to LC. Alpha and beta diversities were differ between all treated groups. Beta-catenin gene expression was significantly decreased in the gut tissue of OT (p≤0.0001) when compared to other groups. No changes were observed in occludin, cadherin and zonulin gene expression in the gut tissue. Conclusion: The synbiotics supplementation prevents excessive weight gain, modulates the gut microbiota, and reduces beta-catenin expression in ob/ob mice.
Tandem repeats ubiquitously flank and select translation initiation sites
Authors: Maddi Ali M.A. , Kavousi Kaveh , Arabfard Masoud , Ohadi Hamid , Ohadi Mina 
Published: November 2021

Abstract
Evolutionary divergence in cis-regulatory sequences impacts translation initiation sites (TISs). The implication of tandem repeats (TRs) in TIS selection remains elusive for the most part. Here we employed the TIS homology concept to study a possible link between all categories of TRs and TIS selection. Human and 83 other species were selected, and data was extracted on the entire protein-coding genes (n=1,611,368) and transcripts (n=2,730,515) annotated for those species from Ensembl 102. Two different weighing vectors were employed to assign TIS homology, and the results were assessed in 10-fold validation. On average, every TIS was flanked by 1.19 TRs of various categories within the 120 bp upstream sequence. We detected statistically significant excess of non-homologous TISs co-occurring with human-specific TRs, vice versa. We conclude that TRs are abundant cis elements in the upstream sequences of TISs across species, and there is a link between all categories of TRs and TIS selection.
Sn-doped CdS: A New Intermediate Band Material for Solar Cells
Authors: Yin Jianbo , Yan Xiaobin , Zhu Min 
Published: November 2021

Abstract
In this paper, the electronic structure and optical properties of CdS doped by Sn with different concentrations were investigated by first principles. The calculation results of electronic structure show that the doping of Sn can produce a deep impurity level band in the band structure of CdS. The calculation results of optical property show that Sn doping can increase the light absorption coefficient and conductivity of CdS. The overall calculation results show that Sn doping can produce stable intermediate band structure and significantly improve the optical property of CdS.