bluuebunny/crossref_metadata_2025_split huggingface dataset:
Replicability, Repeatability, and Long-term Reproducibility of Cerebellar Morphometry
Authors: Sörös Peter , Wölk Louise , Bantel Carsten , Bräuer Anja , Klawonn Frank , Witt Karsten 
Published: January 2021

AbstractTo identify robust and reproducible methods of cerebellar morphometry that can be used in future large-scale structural MRI studies, we investigated the replicability, repeatability, and long-term reproducibility of three fully automated software tools: FreeSurfer, CEREbellum Segmentation (CERES), and automatic cerebellum anatomical parcellation using U-Net with locally constrained optimization (ACAPULCO). Replicability was defined as computational replicability, determined by comparing two analyses of the same high-resolution MRI data set performed with identical analysis software and computer hardware. Repeatability was determined by comparing the analyses of two MRI scans of the same participant taken during two independent MRI sessions on the same day for the Kirby-21 study. Long-term reproducibility was assessed by analyzing two MRI scans of the same participant in the longitudinal OASIS-2 study. We determined percent difference, the image intraclass correlation coefficient, the coefficient of variation, and the intraclass correlation coefficient between two analyses. Our results show that CERES and ACAPULCO use stochastic algorithms that result in surprisingly high differences between identical analyses for ACAPULCO and small differences for CERES. Changes between two consecutive scans from the Kirby-21 study were less than ± 5% in most cases for FreeSurfer and CERES (i.e., demonstrating high repeatability). As expected, long-term reproducibility was lower than repeatability for all software tools. In summary, CERES is an accurate, as demonstrated before, and reproducible tool for fully automated segmentation and parcellation of the cerebellum. We conclude with recommendations for the assessment of replicability, repeatability, and long-term reproducibility in future studies on cerebellar structure.
Shock Metamorphic Features in the Archean Simlipal Complex, Singhbhum Craton, Eastern India: Possible Remnant of a Large Impact Structure
Authors: Singh Ajay K. , Upadhyay Dewashish , Pruseth Kamal Lochan , Mezger Klaus , Nanda Jayanta K. , Maiti Sabyasachi , Saha Dilip 
Published: January 2021

ABSTRACT
The Simlipal complex in eastern India is an elliptical structure with diameter of ca. 50 km coinciding with an elliptical region of high gravity. It overlies the Archaean basement of the Singhbhum craton and has a ring structure characterized by complex series of concentric ridges with inward dipping slopes. Quartz clasts in melt-breccias from the complex display diagnostic shock metamorphic features such as two to three sets of decorated and annealed planar deformation features (PDFs), spall and concussion micro-fractures, and the presence of coesite. They also preserve microstructures suggestive of crystallographically-controlled melting/amorphization along two or three planar directions, and within concussion micro-fractures. The inferred shock pressures in excess of 40–60 GPa are possible only during bolide impact. The Simlipal structure is possibly the remnant of a large complex impact crater having an original diameter of at least 50 km. Although zircons from an impact melt rock furnish a concordia age of 3107±14 Ma, in the absence of any unambiguous shock metamorphic effects in them, it is difficult to assign the age to the impact event. Therefore, the age of the impact is currently unconstrained.
Hillichnus agrioensis and Associated Trace Fossils from Hettangian to Bajocian Thaiat Member of Lathi Formation, Jaisalmer Basin, Western Rajasthan
Authors: Parihar V. S. , Nama S. L. , Meghwal V. K. , Khichi C. P. , Mathur S. C. 
Published: January 2021

ABSTRACT
The present paper describes the abundant and very well preserved ichnotaxon complex Hillichnus agrioensis, as established by four different morphological levels of exposures. Associated trace-fossils such as Jamesonichnites heinbergi and Ancorichnus ancorichnus are also being reported from the Hettangian to Bajocian Thaiat Member of Lathi Formation of Jaisalmer basin, western Rajasthan, India. The ichnospeices Hillichnus agrioensis is being documented for the first time in India. Morphologically, Hillichnus agrioensis includes straight to gently curved, branched or feather-like (almost flat) structures with a central tube. It is interpreted as a deep-burrowing bi-siphonate or tellinaceans bivalves. The ichnotaxon Jamesonichnites heinbergi is interpreted as a burrow made by an infaunal deposit-feeder (fodinichnion), while Ancorichnus ancorichnus is domichnion and may also solely be the result of locomotion (repichnion). This study suggests the presence of shallow or marginal-marine environment for the abovementioned trace-fossil bearing horizons as trace-fossils characterized by such features have also been found from other parts of the world.
Seasonal Distribution Trends of Benthic Foraminiferal Assemblages from the Saurashtra Coast, Western India
Authors: Buragohain Dipankar , Ghosh Anupam 
Published: January 2021

ABSTRACT
The coastland of Saurashtra is represented by several estuaries, islands and cliffs. Taxonomy and seasonal distribution of the recent benthic foraminifera along the coastal tracts of the Saurashtra region have been documented. Surface sediments were collected from the fifteen stations of this coast in both pre and post-monsoon. A total of 35 calcareous wall structure bearing species are identified. Characteristically, two shallow larger benthic foraminifera Nummulites venosus and Amphistegina radiata are observed. The assemblages are more diverse during the pre-monsoon than the post-monsoon season. The cluster analysis shows two different clusters based on sediment preference and diversity of the assemblages.
Morphotectonic Studies of Ghaggar Basin in the Northwestern Frontal Part of the Himalaya Based on Remote Sensing and GIS Techniques
Authors: Pandey Pooja , Sharma L. N. 
Published: January 2021

ABSTRACT
The sub-Himalayan zone of the Himalaya is bounded by the Main Boundary Thrust (MBT) in the northern side and by the Himalayan Frontal Thrust (HFT) in the southern side. HFT is the youngest major tectonic boundary of the Himalaya, separating the Siwalik Hills from the Indo-Gangetic plains. The HFT and Piedmont fault make the densely populated foothill region vulnerable to seismicity. A morphotectonic study of active faults and frontal anticlines was carried out near the Ghaggar basin along the NW part of the Himalaya. To investigate morphotectonic setup during tectonic deformation, spatial imagery and morphometric parameters extracted from DEM were used along with field investigation. The analysis divulges an important active tectonic setting of the Siwalik foothills, which governs the morphology of the Ghaggar basin and fluvial processes in the area. Variations in the topographic pattern and the interaction of the river drainage system with faults and folds were measured to describe the evolution of tectonic landforms. Drainage pattern development, drainage basin asymmetry young stage of hypsometric curve, active mountain fronts and vigorous down cutting of river indicate active anticline growth. This active fold growth is advanced by the movements along the blind thrust system of the HFT. Morphotectonic evidence such as fracture, fault scarp, river terraces, and active anticlines during field investigation further confirms the recent tectonic activity due to fault-propagated fold growth.
Statistical Study of the Factors Affecting Outdoor Gamma Dose Rate and Impact of Season
Authors: Jindal Manoj Kumar , Sar Santosh Kumar , Baghel Triambak , Singh Wadhwa Daljeet 
Published: January 2021

ABSTRACT
The objective of the study was to find the significant impact of season on the outdoor gamma dose rate including statistical analysis. Outdoor gamma dose rates were studied for 52 locations of the Balod district, Chhattisgarh, India, in summer and winter. Statistical analysis confirmed that there was no significant difference in dose rate between summer and winter. Geology of the area was the most important factor, and meteorological parameters had less influence; consequently, in this investigation, the impact of these parameters were checked through linear regression, cluster, principal component and factor analysis.
Understanding the relation between travel duration and station choice behavior of cyclists in the metropolitan region of Amsterdam
Authors: van Kampen Jullian , Pauwels Eric , der Mei Rob van , Dugundji Elenna R. 
Published: January 2021

AbstractWith 35,000 km of bicycle pathways, cycling is common among persons of all ages less than 65 years in the Netherlands. Bicycle is often seen as a standalone travel mode but when integrated as part of a multimodal trip with train, it can be an important solution for long distance journeys, offering increased flexibility and faster access time compared to other travel modes. In this paper we investigate which factors influence departure station choice on combined bicycle–train and bicycle-metro trips in the metropolitan region of Amsterdam. Data from a mobile app was used to track an individual’s travel behavior over the years 2018 and 2019. A discrete choice model was estimated to see whether people prefer to park their bicycle at the station with the shortest travel duration or one of the stations with a longer travel duration. The final results show that level of education and age negatively influence the choice for cycling to the second closest station. Furthermore, the results show that people with an origin inside Amsterdam prefer to travel to a train station regardless of their destination.
Tribological behavior of black phosphorus nanosheets as water-based lubrication additives
Authors: Wang Qingjuan , Hou Tingli , Wang Wei , Zhang Guoliang , Gao Yuan , Wang Kuaishe 
Published: January 2021

AbstractBlack phosphorus (BP) with a layered structure has been used gradually as a lubrication additive in the tribological area. In this study, BP powders are produced via an easy method of high-energy ball milling using red phosphorus as a raw material. Subsequently, BP nanosheets are prepared via liquid exfoliation in N-methyl pyrolidone solvent. The tribological behavior of BP nanosheets as water-based lubrication additives (BP-WL) is evaluated under Ti6Al4V (TC4)/GCr15 contact. The results suggest that the 70 mg/L BP-WL sample exhibits excellent lubrication performance, whose coefficient of friction (COF) and ball wear rate reduced by 32.4% and 61.1%, respectively, compared with those of pure water. However, as the load increased, the tribological properties of BP-WL reduced gradually because of the agglomeration of BP nanosheets. Based on tribological experiments and worn surface analysis, boundary lubrication mechanisms are proposed. The friction reduced, which is primarily attributed to the low interlaminar shear and adsorption of BP nanosheets. In addition, a tribochemical reaction film comprising TiO2, Al2O3, and Fe2O3 effectively protects the surface of titanium alloy/steel from wear. This new water-based lubrication additive can be used to process titanium alloys.
The potentials of technology complementarity to address energy poverty in refugee hosting landscapes in Uganda
Authors: Kay Sonja , Duguma Lalisa A. , Okia Clement A. 
Published: January 2021

AbstractThe continued influx of refugees into Uganda confronts people and hosting landscapes with severe challenges. Vast volumes of biomass resources are required for energy and building materials. Consequently, woodlands have come under pressure as the key source within refugee-receiving regions. This raises the question of how to simultaneously achieve a higher standard of living and energy autonomy for the population while reducing primary resource demand and safeguarding nature. We propose that nature-based and/or technological adaptions can ameliorate this dramatic and deteriorating situation. We thus evaluated the impact of: (i) building autonomy by growing biomass resources on scale via approaches such as agroforestry and ii) enhancing energy efficiency through use of improved cook stoves (ICS) and switching toward renewable energy sources. Focusing on four Ugandan districts, we analyzed the energy and land demand of households and districts in three scenarios. Our results show all districts running into shortages of biomass resources and cultivable land and two districts already reaching their limits. An efficient use of woodfuel combined with solar energy could reduce primary energy demand by up to 37%. The remaining wood demand could be realized by agroforestry systems thereby ensuring household energy autonomy and access to reliable energy sources. We recommend combining energy efficiency measures and technology to reduce firewood demand with agroforestry solutions to satisfy the remaining necessities. Both are needed to reduce the essistential pressure on woodlands and increase the energy autonomy of refugee-hosting landscapes while respecting stakeholder needs.
A comprehensive study on key management, authentication and trust management techniques in wireless sensor networks
Authors: Gautam Amit Kumar , Kumar Rakesh 
Published: January 2021

AbstractWireless sensor networks (WSN) are the new speed-accelerating technologies worldwide and are used continuously in a range of critical applications. Any damage or compromise to data security could have physical and direct effects on network efficiency and safety. One of the active areas of research is key management, authentication, and trust management in wireless sensor networks (WSN). Since researchers have provided many protection schemes, it is difficult to select which key management or trust management schemes in a specific WSN application suit best. We did a detailed survey in our paper on how the properties of various trust management, authentication, and key management schemes can be used for specific applications. Based on this review, we present the methodologies, advantages, and limitations of the previously proposed key management, authentication, and trust management scheme in WSN. The goal of this thorough analysis is to compare and find the correct security solution that successfully meets the requirements of the application. Moreover, the strength, weaknesses, and open problems are added that can extend more frontiers to get the best security solutions in the future.s
Three-dimensionally ordered macroporous BaTiO3 framework-reinforced polymer composites with improved dielectric properties
Authors: Hu Jin , Zhang Shufen , Tang Bingtao 
Published: January 2021

AbstractPolymer composites with high dielectric constants are highly desired in advanced electronic devices and the modern electrical industry. The dielectric constant of three-dimensional filler-reinforced polymer composites is usually enhanced at the expense of flexibility. Herein, barium titanate inverse opals (BT_IOs) that have three-dimensionally ordered and interconnected macropores are prepared and introduced into a poly (vinylidene fluoride) (PVDF) matrix to tailor their dielectric properties. The composite films with 30 wt% BT_IOs exhibit a dielectric constant of 18.8 at 1 kHz, showing an enhancement of 154% and 35% compared with that of pristine PVDF and their corresponding composites reinforced with barium titanate nanoparticles, respectively. Meanwhile, the dielectric loss is suppressed at 0.088. The BT_IOs/PVDF composite films also maintain good flexibility and can be freely bent. This design of three-dimensionally ordered macroporous filler-reinforced polymer composites with improved dielectric constants and good flexibility presents promising applications of dielectric materials in flexible electronics.
Telemedicine for Patient Management on Expeditions in Remote and Austere Environments: A Systematic Review
Authors: Ting Louise , Wilkes Matt 
Published: January 2021

Telemedicine potentially offers enormous value to expeditions to remote environments. For healthcare professionals, telemedicine can provide access to specialist advice. Where no healthcare professionals are present, telemedicine may be the sole source of expert care. This systematic review appraises and summarizes the current literature regarding telemedicine in patient management on expeditions to remote locations and identifies areas for future research. MEDLINE and EMBASE were systematically searched for relevant articles from 1980 through February 2018. Data were handled according to the PRISMA process and analyzed using type-specific critical appraisal checklists where possible. Two hundred twenty-five articles were identified, 33 of which were included in this systematic review. They encompassed a variety of remote environments, including maritime (13), polar (9), mountainous (5), jungle (1), and multiple austere environments (6). Although some environments were better reported than others, many overarching concepts were generalizable. Through channels of communication that included telephone, radio, videoconferencing, and email, telemedicine has been used effectively in a range of environments to initiate treatment, follow up with patients, and determine the appropriateness of evacuation. Telementoring, in which a remote expert guides a local care provider in performing a procedure or task, is a promising aspect of telemedicine that is currently being developed. As technology advances, the scope of telemedicine will continue to expand. However, each new telemedical development must be shown to do more than simply function in a remote environment. Instead, new technologies should be tested for improved patient, practitioner, or expedition outcomes, within a telemedical system.
GNA13 regulates BCL2 expression and the sensitivity of GCB-DLBCL cells to BCL2 inhibitors in a palmitoylation-dependent manner
Authors: Xia Zhizhou , Zhang Xiuli , Liu Ping , Zhang Ruihong , Huang Zhangsen , Li Donghe , Xiao Xinhua , Wu Min , Ning Nannan , Zhang Qianqian , Zhang Jianmin , Liu Mingzhu , Jiao Bo , Ren Ruibao 
Published: January 2021

AbstractGNA13, encoding one of the G protein alpha subunits of heterotrimeric G proteins that transduce signals of G protein-coupled receptors (GPCR), is frequently mutated in germinal center B-cell-like diffuse large B-cell lymphoma (GCB-DLBCL) with poor prognostic outcomes. Due to the “undruggable” nature of GNA13, targeted therapy for these patients is not available. In this study, we found that palmitoylation of GNA13 not only regulates its plasma membrane localization, but also regulates GNA13’s stability. It is essential for the tumor suppressor function of GNA13 in GCB-DLBCL cells. Interestingly, GNA13 negatively regulates BCL2 expression in GCB-DLBCL cells in a palmitoylation-dependent manner. Consistently, BCL2 inhibitors were found to be effective in killing GNA13-deficient GCB-DLBCL cells in a cell-based chemical screen. Furthermore, we demonstrate that inactivating GNA13 by targeting its palmitoylation enhanced the sensitivity of GCB-DLBCL to the BCL2 inhibitor. These studies indicate that the loss-of-function mutation of GNA13 is a biomarker for BCL2 inhibitor therapy of GCB-DLBCL and that GNA13 palmitoylation is a potential target for combination therapy with BCL2 inhibitors to treat GCB-DLBCL with wild-type GNA13.
AMDP-Leitfaden in leichter Sprache für die
psychopathologische Befunderhebung bei Menschen mit geistiger
Behinderung
Authors: Elstner Samuel , Diefenbacher Albert , Stieglitz Rolf-Dieter 
Published: January 2021

ZusammenfassungDie Studie überprüft Praktikabilität einer modifizierten
Version des AMDP-Interviewleitfadens (AMDP-ILF) in der Anwendung bei Menschen
mit geistiger Behinderung (MmgB). Bei 19 Patienten wurden die Symptome
für Selbst- und Selbst-/Fremdbeurteilung gemäß
des AMDP-ILF in der Original-, in der modifizierten Version und in freier
Frageform auf Verständlichkeit bei Menschen mit geistiger Behinderung
überprüft. Mit dem Original-AMDP-ILF konnten 50% der
MmgB eine verwertbare Antwort zu den Fragen der jeweiligen Items geben, weitere
85–90% konnten zusätzlich mit der Version in leichter
Sprache erreicht werden. Die Studie zeigte deutliche Hinweise, dass der
modifizierte AMDP-ILF ein geeignetes Instrument zur psychopathologischen
Befundung bei MmgB ist.
Effekte akzentuierter sensomotorischer Reize bei chronischen Rückenschmerzpatienten – eine kontrollierte Pilotstudie
Authors: Otten Anne , Schroeder Jan 
Published: January 2021

Zusammenfassung
Hintergrund In der medizinischen Trainingstherapie ist die priorisierte Behandlungsmethode bei Rückenbeschwerden häufig ein maschinell geführtes Krafttraining. Dabei lassen Studien vermuten, dass eine gestörte neuronale Steuerung und unzureichende sensorische Fähigkeiten der stabilisierenden Muskulatur Teil der Pathologie bei Rückenbeschwerden sind. In der vorliegenden Studie wurden Effekte eines additiven sensomotorisch intensivierten Stabilisationstrainings evaluiert.
Material und Methoden Zehn Patienten (49±4 Jahre, BMI 27±4 kg/m²) absolvierten über acht Wochen 2-mal wöchentlich ein 60-minütiges Kraftaufbautraining an Geräten (TRENA), 11 Probanden (46±5 Jahre, BMI 26±4 kg/m²) absolvierten zusätzlich ein 30-minütiges Stabilisationstraining (IRENA). Vor und nach dem Interventionszeitraum wurden Daten zur rückenspezifischen Funktionskapazität (FFbH-R) und zur Kraftausdauer der Rückenstrecker (Biering-Sørensen-Test) erhoben.
Ergebnisse IRENA Patienten erzielten in der Funktionskapazität signifikant größere Zuwächse als die TRENA Patienten (∆+14 vs. ∆+10%; F[1;19]=6,832; p=0,017). Der Zugewinn der IRENA Gruppe im Kraft-Test war jedoch nicht signifikant größer (∆+52 vs. ∆+44%; F[1;19]=3,965; p=0,061).
Schlussfolgerungen Das additive Stabilisationstraining führte zu deutlicheren Verbesserungen funktioneller Einschränkungen als die alleinige Standardversorgung durch Gerätetraining, auch wenn sich das nicht durch entsprechend deutlichere Verbesserungen im Kraftausdauerverhalten objektivieren ließ.
Synthesis of Polycycles and Oxacycles via Tandem Metathesis of endo-Norbornene Derivatives
Authors: Kotha Sambasivarao , Pulletikurti Sunil , Fatma Ambareen , Dhangar Gopal , Naidu Gonna Somu 
Published: January 2021

AbstractHere, we have demonstrated that the presence of a carbonyl group at C7 position prevents the olefin metathesis of endo-norbornene derivatives due to complexation of the metal alkylidene. Time-dependent NMR studies showed the presence of new proton signals in the metal alkylidene region, which indicate the formation of metal complex with the carbonyl group of the substrate. These observations were further proved by ESI-MS analysis. Whereas computational studies showed that the catalyst was interacting with the C7 carbonyl group and aligned perpendicular to that of norbornene olefin. These endo-keto norbornene derivatives were reduced to hydroxyl derivatives dia­stereoselectively. Ring-rearrangement metathesis (RRM) of these hydroxyl derivatives, produced the [6/5/6], and [5/6/5] carbo-tricyclic cores of natural products in one step. Whereas the RRM of O-allyl derivatives, delivered the oxa-tricyclic compounds in a single step with excellent yields.
Synthesis of Substituted β-Styrylmalonates by Sequential Isomerization of 2-Arylcyclopropane-1,1-dicarboxylates and (2-Arylethylidene)malonates
Authors: Novikov Roman A. , Tomilov Yury V. , Borisov Denis D. , Chermashentsev Grigorii R. 
Published: January 2021

AbstractA method has been developed for the synthesis of substituted β-styrylmalonates by conversion of 2-arylcyclopropane-1,1-dicarboxylates (ACDCs) in the presence of gallium trichloride into the corresponding­ 1,2-zwitterionic intermediates or (2-arylethyl­idene)malonates, followed by treatment with pyridine at room temperature leading to an isomerization of the emerging double bond. This method allows one to expand these reactions to include ACDCs with acceptor substituents at the aromatic ring.