bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synoptic Climatology of Weather Parameters Associated With Tropical Cyclone Events In The Coastal Areas of Bay of Bengal
Authors: Badhan Mehnaz Abbasi , Farukh Murad Ahmed , Hossen Md. Al- Mussabbir , I Abu Reza Md. Towfiqul 
Published: November 2021

Abstract
Tropical cyclones (TCs) are the most devastating weather phenomena that trigger massive loss of property and life in the coastal areas of the Bay of Bengal (BoB). Scientific understanding of TCs occurrence can aid policy-makers and residents in coastal areas to take necessary actions and appropriate planning in advance. In this study, we aimed to examine the possible linkage of weather parameters with deadly 22 TCs events in the BoB from 1975 to 2014 using principal component analysis, K-mean clustering and General circulation model (GCMs). Results showed that among 22 TCs, cluster 1 belongs to 12 TCs which occurred under the same atmospheric situation when the sea level pressure (SLP) was below 990hPa, and the temperature ranged from 300C to 390C. A deep negative anomaly of SLP and temperature was observed up to 500hPa levels. In contrast, a negative depression was found at 300hPa geopotential height (GPH) over the study area. Cluster 2 consisted of 9 TCs when SLP was below 1000hPa, and the average temperature was 33.50C. A strong negative anomaly was noticed when surface level up to 500 hPa GPH, but dramatically this depression was completely absent at 300hPa geopotential height over the BoB and entire coastal region. Cluster 3 contained only 1 TCs when the atmospheric circumstance was completely diverse, and the SLP was above 1000hPa. The results of the GCM model revealed that the SLP was lower, and the temperature was higher over BoB compared to the North Indian Ocean. We identified the larger depression of SLP and unpredictable temperature anomalies at the upper atmosphere that can trigger an enormous unpredictability throughout the atmospheric level, leading to severe TCs. The outcomes of this study can improve our understanding of weather variables in the upper atmospheric column for forecasting the TCs system more accurately in the future.
Identifying and handling unbalanced baseline characteristics in a non-randomized, controlled, multicenter social care nurse intervention study for patients in advanced stages of cancer
Authors: Schindel Daniel 
Published: November 2021

Abstract
Purpose: Given the psychosocial burdens patients in advanced stages of cancer face, innovative care concepts are needed. At the same time, such vulnerable patient groups are difficult to reach for participation in intervention studies and randomized patient inclusion may not be feasible. This article aims to identify systematic biases respectively selection effects occurring during the recruitment phase and to discuss their potential causes based on a non-randomized, multicenter intervention study with patients in advanced stages of cancer.Methods: Patients diagnosed with at least one of 16 predefined cancers were recruited at four hospitals in three German cities. The effect of social care nurses’ continuous involvement in acute oncology wards was measured by health-related quality of life (EORTC QLQ-C30) and other patient-reported outcomes. Absolute standardized mean difference was calculated as a standardized effect size to test baseline characteristics balance between the intervention and control groups.Results: The study enrolled 362 patients, 150 in the intervention and 212 in the control group. Except for gender, both groups differed in relevant socio-demographic characteristics, e.g. regarding age and educational background. With respect to the distribution of diagnoses, the intervention group showed a higher symptom burden than the control group. Moreover, the control group reported better quality of life at baseline compared to the intervention group (52.6 (SD 21.7); 47.8 points (SD 22.0), ASMD=0.218, p=0.044). Conclusion: Overall, the intervention group showed more social and health vulnerability than the control group. Among other factors, the wide range of diagnoses included and structural variation between the recruiting clinics increased the risk for bias. We recommend a close, continuous monitoring of relevant social and health-related characteristics during the recruitment phase as well as the use of appropriate statistical analysis strategies for adjustment, such as propensity score methods. Trial registration: German Clinical Trials Register (DRKS-ID: DRKS00013640); registered on 29th December 2017.
Identification of Therapeutic Targets and Prognostic Biomarkers of IGF2BPs in the Lung Cancer Microenvironment
Authors: Wang Xuanzheng , Kong Weina , Guo Fan , Sha Ruocheng , Zhao Gang , Qiao Wenbin , Xu Keming , Feng Yangchun , Sun Wei , Ma Xiumin 
Published: November 2021

Abstract
Background: Lung cancer is one of the most common malignances with an ever-increasing incidence and high mortality. The insulin-like growth factor 2 mRNA-binding proteins (IGF2BPs) as RNA-binding proteins play an important role in messenger RNA (mRNA) regulation during tumor development. Even so, the expression and prognostic values of IGF2BPs in lung cancer have not been clarified.Main methods: To address this issue, the study investigated the roles of IGF2BPs in the prognosis of lung cancer by using public databases and quantitative real-time PCR (Q-PCR).Results: The transcriptional levels of IGF2BP1/2/3 in lung cancer tissues were significantly elevated, associating with pathological stages and poor prognosis of overall survival (OS) and progression-free survival (FP) in lung cancer patients. A high mutation rate of IGF2BPs (24%) was also observed of patients with lung cancer. The functions of differentially expressed IGF2BPs are primarily related to the spliceosome, hippo signaling pathway and transcriptional misregulation in cancer. Finally, we found significant correlations among the expression of IGF2BPs and the infiltration of six types of immune cells (B cells, CD8+ T cells, CD4+ T cells, macrophages, neutrophils, and dendritic cells).Conclusions: The results indicated that high mRNA expression of IGF2BP1/2/3 was found in lung cancer tissues, significantly associating with tumor grades and poor prognosis of OS and FP. Our results may provide insights for the selection of therapeutic targets and prognostic biomarkers for lung cancer patients.
In-hospital Cardiac Arrest in Patients With Heart Failure: Long- and Short-term Survival and Trends
Authors: Aune Emma , McMurray John , Lundgren Peter , Sattar Naveed , Israelsson Johan , Nordberg Per , Herlitz Johan , Rawshani Araz 
Published: November 2021

Abstract
In patients with heart failure (HF) who suffered in-hospital cardiac arrest (IHCA), little is known about the characteristics, survival and neurological outcome. We used the Swedish Registry of Cardiopulmonary Resuscitation to study this, including patients aged ≥18 years suffering IHCA (2008-2019), categorised as HF alone, HF with acute myocardial infarction (AMI), AMI alone, or other. Odds ratios (OR) for 30-day survival, trends in 30-day survival, and the implication of HF phenotype was studied. 6378 patients had HF alone, 2111 had HF with AMI, 4210 had AMI alone. Crude 5-year survival was 9.6% for HF alone, 12.9% for HF with AMI and 34.6% for AMI alone. The 5-year survival was 7.9% for patients with HF and left ventricular ejection fraction (LVEF) ≥50%, 15.4% for LVEF <40% and 12.3% for LVEF 40-49%. Compared with AMI alone, adjusted OR (95% CI) for 30-day survival was 0.66 (0.60-0.74) for HF alone, and 0.49 (0.43-0.57) for HF with AMI. OR for 30-day survival in 2017-2019 compared with 2008-2010 were 1.55 (1.24-1.93) for AMI alone, 1.37 (1.00-1.87) for HF with AMI and 1.30 (1.07-1.58) for HF alone. Survivors with HF had good neurological outcome in 92% of cases.
Morphological and Molecular Characterization of Quinisulcius curvus from China
Authors: Gu Jianfeng , Munawar Maria , Castillo Pablo , Cai Bo 
Published: November 2021

Abstract
A stunt nematode species, Quinisulcius curvus, recovered from the rhizosphere of sea randa (Guettarda speciosa), is described and characterized herein based on integrative taxonomy. Morphometrics and distribution of all reported populations of Q. curvus are also discussed. The Chinese population of Q. curvus displayed slight variation in stylet length; however, the rest of the characters matches well with the original description. This is the first record of Q. curvus from Hainan, China, and the first molecular characterization for this species. Phylogenetic analysis based on partial 18S, 28S and ITS sequences placed Q. curvus with related stunt nematodes species, but clearly separated from them. The present study expanded the geographic record and provided molecular data on Q. curvus from China.
Morphological and molecular characterization of Bitylenchus hispaniensis (Nematoda: Telotylenchidae) from Iran
Authors: Abdolkhani Abbas , Azimi Sedighe 
Published: November 2021

Abstract
During a survey on the biodiversity of plant-parasitic nematodes in Khuzestan province (southwest Iran), Bitylenchus hispaniensis was discovered around the rhizosphere of the euphrates poplar tree. The morphological and morphometric data were provided for the recovered species. To the best of our knowledge, this is the first report of B. hispaniensis from Iran and for the first time in association with euphrates poplar worldwide. Molecular phylogenetic analyses of the Iranian population of B. hispaniensis using the D2-D3 expansion segments of 28S rDNA and internal transcribed spacer (ITS rDNA) sequences using Bayesian inference (BI), showed a maximally supported clade with other sequences of the species.
Vanishing waters: water chemistry of temporary rock pools of the Western Ghats, India
Authors: Kulkarni Aboli , Roy Surajit , Yogeshwaran Murugesan , Shigwan Bhushan , Vijayan Smrithy , Kshirsagar Pranav , Datar Mandar N. , Karthick Balasubramanian 
Published: November 2021

AbstractThe freshwater rockpools support high endemic biodiversity but are poorly studied habitats in the Western Ghats biodiversity hotspot. These freshwater rock pools are situated on outcrops at various elevations in the Western Ghats and are composed of different bedrocks such as laterite and basalt. We aimed to analyze the water quality, geographical position based differences in the water chemistry and the role of bedrock in determining the water chemistry of the rock pools. Our study showed a wide range of water quality variables such as pH, conductivity, and ionic contents that attributed to the natural variation. We observed a drastic variation in the anions and cations at low elevation pools. Rock type and precipitation are influencing the ionic concentration; for example, Calcium and Bromide could be attributed to the seasonal precipitation and geomorphology. This documentation of physicochemical properties of the Western Ghats rock pools can form a baseline for further detailed studies.
AVALIAÇÃO DO NÍVEL DE CONHECIMENTO DOS PACIENTES ATENDIDOS NA ATENÇÃO BÁSICA SOBRE A PREVENÇÃO DOS CÂNCERES DE CABEÇA E PESCOÇO
Authors: Néry do Nascimento Arlon , Lorrana Oliveira Araújo Taynara , Ellen Bezerra Meneses Lyandra , Carneiro Alves Pereira Mayane 
Published: November 2021

Introdução: O câncer de cabeça e pescoço é um conjunto de neoplasias que atingem o trato aero digestivo superior. Essas neoplasias apresentam sintomatologia variada, que depende da localização do tumor, gravidade e tempo de ocorrência. Objetivo: Avaliar o nível de conhecimento da população, usuária da atenção básica, acerca da prevenção e tratamento dos Cânceres de Cabeça e Pescoço. Metodologia: Trata-se de um estudo de campo transversal descritivo, em que se coletou informações acerca do conhecimento sobre cânceres de cabeça e pescoço, informações sociodemográficas, histórico familiar, características clínicas e de tratamentos. A coleta foi realizada em julho de 2019, em três Estratégias de Saúde da Família da cidade de Piripiri-PI. A pesquisa foi submetida e aprovada pelo Comitê de Ética em Pesquisa com o Parecer nº 3.221.522. Resultados e discussão: A maioria dos entrevistados foram mulheres solteiras com idade média de 44,4 anos e de baixa renda. Dentre os questionamentos realizados, grande parte não soube responder questões sobre conhecimentos gerais a respeito dessas enfermidades. Outro fator importante é a baixa procura por serviços de saúde. Conclusões: Observou-se que os entrevistados apresentam desinformação a respeito da prevenção e tratamento desse grupo de cânceres, sendo necessário o fortalecimento de ações de educação popular em saúde.
Positive Aspects, Negative Aspects and Challenges Associated with Stem
Cell Therapy for COVID - 19: A Mini-review
Authors: Nagoba Basavraj , Gavkare Ajay , Rayate Abhijit , Mumbre Sachin 
Published: November 2021

:
Like any other pandemic, Covid-19 scenario has also demanded effective treatment options.
The circumstances demand to utilize all the possible weapons in the armamentarium. There
have been many issues regarding the short-term and long-term safety and efficacy of these options.
Some options are like uncharted seas and these need a detailed and critical review with respect to
safety, efficacy, feasibility and financial constraints. Mesenchymal stem cells (MSCs) therapy has
been studied for many years for its potential role in diseases with complex pathogenesis. Its efficacy
in controlling cytokine imbalance and immuno-modulatory properties is well proven. These effects
are being extensively studied for potential extension of the benefits for an effective option for
management of COVID-19 patients with severe respiratory involvement. In this mini-review, an attempt
has been made to review positive aspects, negative aspects, and challenges influencing
MSCs therapy in the management of COVID-19 disease. The results of various studies and literature
reviews show that MSCs therapy can be considered as one of the potential options.
This article reviews the role of Mesenchymal Stem Cell (MSC) transplantation in critically ill
SARS-COV-19 patients with lung involvement. The MSCs counteract the cytokine storm, regulate
the immune responses, facilitate the expression of essential growth factors, and eventually improve
the local milieu and promote the restoration of pulmonary vascular and alveolar linings for early
healing. As with all new therapeutic options, MSC therapy will also have to stand the test of time
with respect to safety, specificity, and constraints like mass production and “available for all” at
“affordable cost.”
Primary Hyperparathyroidism in the Common Orthopaedic Practice
Authors: Sferopoulos Nikolaos K. 
Published: November 2021

An extensive review of the publications on primary hyperparathyroidism (pHPT) is presented in this report. It has strongly been emphasized in the literature that patients with pHPT may present either with the classical symptomatology or with asymptomatic disease, emerged due to biochemical screening. The clinical and epidemiological presentation of pHPT in western countries has changed profoundly during the past few decades, and bone disease is nowadays a distinct rarity. The introduction of serum calcium screening for osteoporosis and the technological advances in the laboratory assessment of parathyroid hormone have played important roles in early diagnosis. Subsequently, the disease is increasingly being detected as asymptomatic hypercalcaemia without guiding signs or symptoms. A third type of disease, the normocalcaemic variant, has been recently described in the literature. However, the potential diagnosis of pHPT should always be on the orthopaedics’ list of differential diagnoses in female or elderly patients with vertebral fractures and nephrolithiasis, either symptomatic or asymptomatic, as well as when solitary or multiple osteolytic lesions are encountered on the radiographs.Additionally, a middle aged woman with parathyroid adenoma and subsequent brown tumors detected on the pelvic radiographs is reported. Her initial laboratory findings indicated a minimal increase of the serum calcium, a mild increase of the erythrocyte sedimentation rate, and a significant increase in total serum alkaline phosphatase. Finally, the detection of elevated parathyroid hormone levels indicated the diagnosis of pHPT and necessitated imaging studies of the parathyroid glands, which indicated a parathyroid adenoma. Following successful excision of the parathyroid adenoma, the patient suffered from the hungry bone syndrome. After a follow-up of 20 years, the patient had normal calcium, vitamin D, and parathyroid hormone serum levels, while a pelvic radiograph indicated no significant changes in the appearance of the brown tumors.
The Chaebol’s contribution on South Korea nation branding through Korean wave
Authors: Dannita Sarah , Deniar Shannaz 
Published: November 2021

Korean Wave atau yang dikenal dengan Hallyu Wave menjadi salah satu ciri nation branding dari Korea Selatan. Sebagai sebuah kebutuhan dari negara untuk memperkuat eksistensinya, kajian mengenai nation branding menjadi menarik untuk melihat bagaimana strategi yang dipilih dari aktor negara serta bagaimana bentuk kolaborasi yang mereka lakukan. Penelitian ini menelaah kontribusi Chaebol dalam penguatan nation branding melalui Korean Wave. Dengan menggunakan Nation Branding Index oleh Simon Anholt, penelitian ini melihat bagaimana bentuk kontribusi dan kolaborasi antar aktor dalam enam index, yakni national governance, export promotion, tourism, investment and immigration, cultural/heritage relations, dan public/ people. Hasil penelitian ini memperlihatkan usaha Chaebol melalui kerjasama, joint venture, produksi, distribusi, serta promosi konten-konten dalam hallyu terlihat berdampak signifikan baik dalam citra promosi maupun pemasaran produk kepada masyarakat internasional.

The Korean Wave, also known as the Hallyu, is one of the nation branding’s characteristics of South Korea. As a need from the state to strengthen its existence, the study of nation branding is interesting to see how the strategies chosen by state actors are and what forms of collaboration they take. This study will examine the contribution of Chaebol in strengthening nation branding through the Korean Wave. By using the Nation Branding Index by Simon Anholt, this study looks at the forms of contribution and collaboration between actors in six nation branding indexes, namely national governance, export promotion, tourism, investment and immigration, cultural/heritage relations, and public/people. The results of this study show that Chaebol's strategies through cooperation, joint ventures, production, distribution, and promotion of hallyu content has a significant impact both in image promotion and product marketing to the international community towards South Korea.
Tantangan primordialisme dalam upaya membangun budaya politik nasional
Authors: Nurjaman Asep 
Published: November 2021

Persatuan dan kesatuan bangsa sangat penting dalam sebuah negara bangsa (nation state). Indonesia dihadapkan pada persoalan heterogenitas suku, bahasa, ras, agama, dan kedaerahan yang menjadi tantangan dalam membangunan budaya politik nasional. Oleh karena itu tujuan artikle ini adalah untuk mengkaji ikatan primordial dalam proses national and character building. Penelitian ini menggunakan pendekatan kualitatif dengan metode studi literatur. Sementara teknis analisanya menggunakan analisis isi. Kebutuhan data diambil dari berbagai sumber, baik buku, jurnal, maupun dokumen cetak dan digital. Temuan penelitian menunjukan bahwa (1) Primordialisme menjadi unsur yang paling penting dalam kenakaragaman bangsa dan berperan dalam menumbuhkan patriotisme, namun menjadi tantangan ketika membangun budaya nasional, (2) negara melakukan berbagai upaya dalam mempersatukan keragaman memalui berbagai kebijakan seperti monitisasi ideologi yang cenderung mengarah ke totaliter. Hal tersebut berimplikasi pada marginalisasi dan eliminasi yang menghambat kebebasan yang penting dalam membangun kreativitas dan inovasi dalam negara demokrasi.

Unity and diversity is the most urgent thing in a nation-state (nation-state). Indonesia is faced with the problem of ethnic, linguistic, racial, religious, and regional heterogeneity which is a challenge in building a national political culture. Therefore, the purpose of this paper is to examine primordial bonds in the process of national and character building. This study used a qualitative approach with a systematic literature method. While the technical analysis used content analysis. Data needs were taken from various sources, books, journals, and documents, both printed and digital. The research findings show that: (1) Primordialism is the most important element in the diversity of the nation and play a role in fostering patriotism, but it becomes a challenge when building a national culture. (2) The state makes various efforts to unite diversity through various policies such as ideology uniformity which tends to lead to totalitarian. This has implications for marginalization and elimination that hinder freedom which is important in building creativity and innovation in a democratic country.
VIABILITAS BENIH KEDELAI (Glycine max [L.] Merril) SEJALAN DENGAN PENYIMPANAN ALAMIAH DAN PENGUSANGAN CEPAT DENGAN ETANOL
Authors: Pramono Eko , Hadi M. Syamsoel , Kamal M. 
Published: November 2021

Storing seeds always causes deterioration, mainly due to the long storage time and rapid aging treatment using ethanol. This study aimed to compare the viability of soybean seeds due to the natural storage period and due to accelerated aging with ethanol. The lot of Argomulyo soybean seeds was divided into five subloties. Sublot-1 was the soybean seeds given a natural storage under temperature of ± 26 ºC for 12 months. Sublot-2 was the soybean seeds given a natural storage under temperature of ± 18 ºC for 12 months. Sublot-3 was the soybean seeds applicated with the treatments of the absorption period 0-12 hours to ethanol solution of 8 % (LPLE8). Sublot-4 was soybean seeds applicated with the treatments of the exposure periods 0-180 minutes to saturated ethanol 96% vapour (LDUJE). Sublot-5 was soybean seeds applicated with the treatments of imbibition periods 0-24 hours prior to be exposured on saturated 96% ethanol vapour for 40 minutes (LIPPC). The main variable observed was the percentage of normal seedlings (PKN). The rate of decline in the viability of soybean seeds during storage of 0-12 months under the storage room temperature of 26 C or 18 C respectively a) was greater than that treated with ethanol-8% absorption period of 0-12 hours, and b) did not differ from those treated with 96% 0-180 minutes ethanol saturated vapor treatment period and treated with 0-24 hour imbibition period before exposure to 96% ethanol saturated vapor for 40 minutes. Keywords: Aging, ethanol, normal seedling, seed viability, storage