bluuebunny/crossref_metadata_2025_split huggingface dataset:
How does rural in-migration affect forest clearing and smallholder land use in tropical forest frontiers? Evidence from the Zambian Miombo woodlands
Authors: Zhunusova Eliza , Kazungu Moses , Sadeghi Azin , Kalaba Felix Kanungwe , Kabwe Gillian , Günter Sven 
Published: January 2025

AbstractOne of the main sources of increasing population pressure in forested landscapes of Zambia is in-migration from other rural areas. This in-migration is driven by environmental degradation and limited employment options in the villages of origin, and, to a limited extent, in-migration from urban areas due to widespread unemployment and increased cost of living in cities. The current study examines the relationship between in-migration, forest clearing, and land use change in forested landscapes in Zambia. This question is especially relevant considering that in 2020, 85% of total carbon dioxide emissions in the country were attributed to Land Use, Land-Use Change, and Forestry (LULUCF). Based on a dataset of 1123 households living in or near the Miombo woodlands in Zambia, we estimate a multivariate tobit model to explain forest clearing and the area under annual crops at the household level. Households reported the availability of agricultural land, natural resources, or fertile soils as their main reason for migration. Regression results showed that being an in-migrant household was associated with 28% more forest area cleared for crop production during the 5 years prior to data collection and with an 8% increase in area cultivated with annual crops. Our results add to limited available quantitative evidence on the impacts of in-migration on forest clearing and land use in tropical forest frontiers at the micro-scale. With rising in-migration in the future that leads to further forest clearing in migrant-receiving areas, the cycle can repeat itself, where increasing population pressure and deforestation can lead to environmental degradation and migration to other forested landscapes. To address this chain, future policy should aim to deal with the root causes of internal migration, including by investing in landscape restoration and sustainable agricultural intensification in origin areas.
Phraseology and Terminology Challenges and Approach to Translating Divorce Decrees
Authors: Halimi Sonia A. 
Published: January 2025

AbstractIn the context of international mobility and migration, where highly sensitive documents relating to personal status or qualifications need to be translated, a certified translation of official documents is on the increase. A certified translation requires the involvement of a sworn translator who guarantees the exact reproduction of official documents to be registered with a foreign authority. As a personal status document, divorce decrees must also be translated with rigorous standards in order to be recorded elsewhere. The rules governing Arabic divorce decrees are codified separately in Arabic civil codes and refer to the Family Code or Personal Status Code. Matters related to personal status are subject to religious considerations and contain religiously charged terms that are strictly defined in accordance with the Islamic law and require special attention when translated. This paper aims to explore translation challenges of a particular type of Arabic civil status deed, namely divorce decrees. For this purpose, the study first explains the most prominent concepts relating to certified translation and to Arabic divorce decrees. A number of Arabic divorce decrees are then subjected to a descriptive analysis to define shared linguistic features and to outline the relevant translation techniques in dealing with religiously embedded terminology and phraseology. The relevance of this analysis is assessed by examining a French certified translation of an Arabic divorce document in order to draw meaningful conclusions about the approach to translating this legal genre.
BayesAge 2.0: a maximum likelihood algorithm to predict transcriptomic age
Authors: Mboning Lajoyce , Costa Emma K. , Chen Jingxun , Bouchard Louis-S. , Pellegrini Matteo 
Published: January 2025

AbstractAging is a complex biological process influenced by various factors, including genetic and environmental influences. In this study, we present BayesAge 2.0, an upgraded version of our maximum likelihood algorithm designed for predicting transcriptomic age (tAge) from RNA-seq data. Building on the original BayesAge framework, which was developed for epigenetic age prediction, BayesAge 2.0 integrates a Poisson distribution to model count-based gene expression data and employs LOWESS smoothing to capture nonlinear gene-age relationships. BayesAge 2.0 provides significant improvements over traditional linear models, such as Elastic Net regression. Specifically, it addresses issues of age bias in predictions, with minimal age-associated bias observed in residuals. Its computational efficiency further distinguishes it from traditional models, as reference construction and cross-validation are completed more quickly compared to Elastic Net regression, which requires extensive hyperparameter tuning. Overall, BayesAge 2.0 represents a step forward in tAge prediction, offering a robust, accurate, and efficient tool for aging research and biomarker development.
Integration of Immune Cell-Target Cell Conjugate Dynamics Changes the Time Scale of Immune Control of Cancer
Authors: Yang Qianci , Traulsen Arne , Altrock Philipp M. 
Published: January 2025

Abstract
The human immune system can recognize, attack, and eliminate cancer cells, but cancers can escape this immune surveillance. Variants of ecological predator–prey models can capture the dynamics of such cancer control mechanisms by adaptive immune system cells. These dynamical systems describe, e.g., tumor cell-effector T cell conjugation, immune cell activation, cancer cell killing, and T cell exhaustion. Target (tumor) cell-T cell conjugation is integral to the adaptive immune system’s cancer control and immunotherapy. However, whether conjugate dynamics should be explicitly included in mathematical models of cancer-immune interactions is incompletely understood. Here, we analyze the dynamics of a cancer-effector T cell system and focus on the impact of explicitly modeling the conjugate compartment to investigate the role of cellular conjugate dynamics. We formulate a deterministic modeling framework to compare possible equilibria and their stability, such as tumor extinction, tumor-immune coexistence (tumor control), or tumor escape. We also formulate the stochastic analog of this system to analyze the impact of demographic fluctuations that arise when cell populations are small. We find that explicit consideration of a conjugate compartment can (i) change long-term steady-state, (ii) critically change the time to reach an equilibrium, (iii) alter the probability of tumor escape, and (iv) lead to very different extinction time distributions. Thus, we demonstrate the importance of the conjugate compartment in defining tumor-effector T cell interactions. Accounting for transitionary compartments of cellular interactions may better capture the dynamics of tumor control and progression.
Building Bridges in a Sanctuary City: Pan-ethnic Identity Among Precarious Latino Immigrants
Authors: Mallet-Garcia Marie L. , Garcia Edwin 
Published: January 2025

AbstractThis article examines the strategies developed at the local level to strengthen pan-ethnic solidarity within Latino communities in the San Francisco Bay Area. It explores how local organizations and migrant communities may foster a pan-ethnic identity and the subsequent effects on the inclusion process of Latino immigrants with precarious legal status. Based on 87 in-depth interviews, this study offers a novel perspective on integration by focusing on intra-ethnic dynamics within Latino communities, particularly at the local level, rather than broader inter-ethnic or national contexts. The findings highlight the critical role of local contexts in shaping the mechanisms of inclusion for Latino immigrants, revealing the complexities of identity formation under conditions of legal precarity. In particular, they show how in exclusionary contexts, within-group solidarity can be built. This research contributes to broader sociological and political debates on immigrant inclusion, pan-ethnic identity formation, and the influence of local environments in these processes.
The effects of diet enhancement on the health of commercial bumblebee colonies
Authors: Hulse Rosaline A. , Van Oystaeyen Annette , Carnell Joanne D. , Beckett Danielle , Grey William G. , Goulson Dave , Wackers Felix , Hughes William O. H. 
Published: January 2025

Abstract
Commercially reared bees provide economically important pollination services for a diversity of crops. Improving their health is important both to maximise their pollination services and to avoid possible pathogen spillover or spillback with wild pollinators. Diet quality may directly or indirectly affect diverse aspects of bumblebee health, including colony development, individual size and immune health, but the impact of this remains unclear. Here we investigate experimentally the effect of diet quality during bumblebee colony development using three diets: (1) a standard pollen diet used in commercial rearing of colonies for sale, (2) an enhanced diet comprised of a wildflower pollen mix that was expected to be nutritionally superior (including by having an elevated protein content) and (3) a diet of pollen substitute mixed with the standard diet that was expected to be nutritionally poorer. The effect of diet quality on colony health was quantified using colony-level measures (colony weight, size [number of live workers] and number of dead individuals), and individual-level measures (body size, fat body size [proportion of body weight], total haemocyte count and phenoloxidase immune enzyme activity). Diet quality significantly affected colony growth, with colonies fed the enhanced diet growing larger and producing more reproductives than those fed either a standard or poor diet. The enhanced diet also resulted in bees that were significantly larger and had better immune health. The results show that diet can have important effects on the health of commercially reared bumblebees and suggest that the enhancement of standard-rearing diets may improve colony health.
Quantifying the benefits of incorporating biochar in green roof substrates: field study on the highrise rooftop in temperate climate setting
Authors: Petreje Marek , Sněhota Michal , Šípek Václav , Hnátková Tereza , Punčochář Jan , Buchtelík Stanislav , Hardman Michael , Trakal Lukáš 
Published: January 2025

AbstractBiochar is a promising material with a wide range of applications. One area of application is as an additive in substrates for green roofs. Green roofs are a way of mitigating climate change, with biochar offering an opportunity to further enhance this benefit and upscale practice. In this field study, the effect of a 5-vol.% addition of wood-based biochar to a green roof substrate is evaluated with respect to a water balance (reduced runoff, increased evapotranspiration, increased plant available water) and hydrophysical properties. Substrate, with and without biochar amendment, was used in different green roof sections. Laboratory hydrophysical analysis, in-situ Volumetric Water Content and meteorological measurements, alongside vegetation monitoring, enabled the development of a 1D Hydrus water balance model and revealed differences between both of the surveyed green roofs. The study demonstrated that the addition of biochar to the substrate improved its hydrophysical properties, leading to increased water retention (7.7% increase in maximum water capacity) and enhanced vegetation growth The biochar amendment resulted in the minor changes in grain size distribution (increase in the 0.01 to 0.1 mm fraction) and increased substrate moisture, which is related to an increase in the plant-available water content (14.2%). This was observable in the retention curves and resulted in an increased moisture availability for plants, leading to an increase in vegetation cover in areas with biochar. The numerical analysis using Hydrus-1D soil hydraulic model showed that the inclusion of biochar in the substrate resulted in a 23.5% increase in evapotranspiration and a 54.7% decrease in runoff. These findings suggest that the addition of biochar to the green roof substrate could enhance the system's capacity to retain water, reduce runoff and bulk density, and increase the amount of water available for plant growth. The study provides evidence for the potential of wood-based biochar as a sustainable and effective addition to green roof substrates, contributing to the development of more resilient and sustainable urban environments.
Graphical Abstract
Fitz-Hugh-Curtis syndrome: a case study of a frequently missed diagnosis
Authors: Gega Zephania D. P. , Lyimo Henry I. , Kitua Daniel W. , Mwanga Ally H. 
Published: January 2025

Abstract
Introduction
Fitz-Hugh-Curtis syndrome (FHCS) is a relatively common complication of pelvic inflammatory disease. However, this diagnosis is frequently overlooked due to its nonspecific symptomatology that often mimics hepatobiliary disorders. This report presents a case of FHCS and offers a review of pertinent clinical considerations.

Case
We describe a case of a 33-year-old sexually active female previously treated for vaginal discharge syndrome, who presented to our facility with worsening right upper quadrant pain. Initial laboratory and imaging findings were inconclusive. However, diagnostic laparoscopy revealed perihepatic “violin string” adhesions consistent with FHCS.

Conclusion
This case underscores the importance of considering FHCS in the differential diagnosis of right upper quadrant pain, especially in individuals with a history of pelvic inflammatory disease. Awareness of this syndrome and its clinical manifestations is crucial for prompt diagnosis and appropriate management.
Relative efficacy of systemic treatments for patients with relapsed/refractory chronic lymphocytic leukemia: a network meta-analysis according to 17p deletion/TP53 mutations
Authors: Kim Jinchul , Cho Jinhyun , Lim Joo Han , Lee Moon Hee 
Published: January 2025

Abstract
Purpose
This network meta-analysis aimed to evaluate the relative efficacy of systemic treatments in patients with relapsed/refractory chronic lymphocytic leukemia (R/R CLL), focusing on key genetic mutations, specifically the 17p deletion and TP53 mutations.

Methods
We conducted a systematic literature review to identify all publicly available randomized controlled trials (RCTs) using PubMed, EMBASE, the Cochrane database, and meeting abstracts published through December 2023. A Bayesian network meta-analysis was performed to estimate the hazard ratios (HRs) for progression-free survival (PFS) with 95% confidence intervals (CIs) and to determine the ranking of the included regimens.

Results
Twelve trials involving 4,437 patients and 13 treatment options were included in the meta-analysis. Venetoclax plus rituximab and zanubrutinib emerged as the most effective treatments for the overall R/R CLL population, showing the lowest PFS HR (HR 0.62, 95% CI 0.32–1.20 and HR 0.65, 95% CI 0.49–0.86, respectively) versus ibrutinib, and were ranked as the best agent (surface under the cumulative ranking curve [SUCRA] value of both 90%, respectively) among the included drugs. In the 17p deletion/TP53 mutation subgroup, zanubrutinib demonstrated the most favorable efficacy (HR 0.52, 95% CI 0.31–0.88 versus ibrutinib) with the highest SUCRA value (97%). In patients without these mutations, venetoclax plus rituximab was the most effective (HR 0.49, 95% CI 0.26–0.94 versus ibrutinib) with a SUCRA value of 94%.

Conclusion
Our findings highlight the superior efficacy of venetoclax plus rituximab and zanubrutinib for treating R/R CLL and confirm that the role of each regimen may vary depending on the clinically significant mutations.
Investigating changes in mediastinal anatomy on severe trauma using post-mortem CT scans and multiparametric 3-D reconstructions: a case series of major trauma
Authors: Midiri Mauro , Re Giuseppe Lo , Salerno Sergio , Barberi Marika Triscari , Fornasari Maria Grazia , Galia Massimo , Malta Ginevra , Argo Antonina , Zerbo Stefania , Albano Giuseppe Davide 
Published: January 2025

AbstractMajor trauma from high-impact events, such as road traffic accidents and crush injuries, often results in fatal injuries with complex and varied mechanisms affecting different regions of the body. In this paper, we review a case series of major trauma involving four unique accidents of destruction to physiological mediastinal anatomy and the aim is to evaluate post-mortem computed tomography (PMCT) with 3D multiparametric reconstruction unusual findings scan with alteration of mediastinal anatomy and then compare with those of traditional autopsy. PMCT is a helpful tool in highlighting traumatic bone injuries, major visceral and vascular lesions of the mediastinum, as well as the presence of foreign body, pneumothorax and hemothorax, guiding the subsequent autopsy. The presence of hemothorax and blood in the mediastinal area reduces the diagnostic effectiveness of the PMCT, limiting the detection of minor vascular and visceral injuries.
A pilot randomized controlled trial of the iPeer2Peer program in adolescents with sickle cell disease: A mixed method study
Authors: Kelenc Lauren , Wiles Brittany , Nishat Fareha , Lalloo Chitra , Nair Anya , Eling Craig , Kirby-Allen Melanie , Simpson Ewurabena , Sinha Roona , Ward Richard , Zempsky William T. , Ahola Kohut Sara , Stinson Jennifer N. 
Published: January 2025

Abstract

Background and objectives:
Sickle cell disease (SCD) is hallmarked by recurrent episodes of severe acute pain and the risk for chronic pain. Remote peer support programs have been shown to effectively improve health outcomes for many chronic conditions. The objective of this study was to examine the feasibility and acceptability of an online peer mentoring program (iPeer2Peer program) for adolescents with SCD.

Method:
A waitlist pilot randomized controlled trial was conducted. Adolescents randomized to the intervention group were matched with trained peer mentors (19–25 years; successfully managing their SCD), consisting of up to 10 sessions of approximately 30-min video calls over a 15-week period. The control group received standard care. The primary outcomes were rates of accrual, withdrawal, and adherence to iP2P program/protocol, with secondary outcomes identifying topics of mentorship–mentee conversations through qualitative analysis.

Results:
Twenty-eight participants (14 intervention; 14 control) were randomized to the study (mean age: 14.8 ± 1.7 years; 57% female). Accrual rate was 80% (28/35) and withdrawal rate was 18% (5/28), with 28% (4/14) adhering to the iP2P program; however, 71% (10/14) of adolescents in the intervention completed at least one call. Based on content analysis of 75 mentor–mentee calls, three distinct content categories emerged: impact of SCD, self-management, transitioning to adulthood with SCD, and general topics.

Conclusion:
The results from this pilot study suggest that the current iteration of the iP2P SCD program lacks feasibility. Future research with the iP2P program can focus improved engagement via personalized mentoring, variable communication avenues, and an emphasis on gender.
Disaster Health Care and Resiliency: A Systematic Review of the Application of Social Network Data Analytics
Authors: Rasouli Panah Hamidreza , Madanian Samaneh , Yu Jian 
Published: January 2025

Abstract

Objectives
This systematic literature review explores the applications of social network platforms for disaster health care management and resiliency and investigates their potential to enhance decision-making and policy formulation for public health authorities during such events.

Methods
A comprehensive search across academic databases yielded 90 relevant studies. Utilizing qualitative and thematic analysis, the study identified the primary applications of social network data analytics during disasters, organizing them into 5 key themes: communication, information extraction, disaster Management, Situational Awareness, and Location Identification.

Results
The findings highlight the potential of social networks as an additional tool to enhance decision-making and policymaking for public health authorities in disaster settings, providing a foundation for further research and innovative approaches in this field.

Conclusions
However, analyzing social network data has significant challenges due to the massive volume of information generated and the prevalence of misinformation. Moreover, it is important to point out that social network users do not represent individuals without access to technology, such as some elderly populations. Therefore, relying solely on social network data analytics is insufficient for effective disaster health care management. To ensure efficient disaster management and control, it is necessary to explore alternative sources of information and consider a comprehensive approach.
Optimizing Triage in Chemical Disasters: Validation of Modified IGSA Criteria for Hydrofluoric Acid Exposure
Authors: Shin Heejun , Oh Se Kwang , Lee Han You , Chung Heajin , Moon Ji Eun , Kang Hee Do 
Published: January 2025

Abstract

Objective
This study aimed to develop and validate the modified irritant gas syndrome agent (IGSA) criteria, utilizing readily available triage information and epidemiologic data to efficiently segregate patients based on the severity of hydrofluoric acid (HFA) exposure.

Methods
A retrospective analysis of 160 patients exposed to HFA was performed to develop the criteria and assess the criteria’s efficacy, focusing on age, respiratory rate, and compliance with IGSA standards. The criteria’s validity was assessed by comparing clinical outcomes between patients meeting the modified IGSA (mIGSA) criteria and those who did not as external and internal.

Results
The mIGSA criteria (or AIR criteria) consisting of the 3 clusters of age greater than 49, IGSA criteria satisfied, and respiratory rate greater than 19 was developed. The area under curve of receiver operating characteristic curve for prediction of the risk of confirmed HFA injury according to AIR criteria was 0.8415 at the external validation.

Conclusions
The mIGSA criteria offer a significant improvement in the triage of HFA exposure incidents, facilitating rapid identification and prioritization of patients with potentially severe outcomes. Future research should aim to further validate these criteria across diverse emergency scenarios, reinforcing their utility in global health emergency preparedness.