bluuebunny/crossref_metadata_2025_split huggingface dataset:
The efficacy of acupressure in managing opioid-induced constipation: Single-blind a randomized controlled study
Authors: YILDIRIM DİLEK , KOCATEPE Vildan , TALU Gül KÖKNEL 
Published: September 2021

Abstract
Purpose

Opioid-induced constipation is one of the heath problems with a negative impact on the quality of life. This randomized-controlled trial aimed to investigate the effects of acupressure therapy on the management of opioid-induced constipation.
Methods

The trial was conducted on 140 patients, who were assigned to the acupressure (n = 70) and the control groups (n = 70). In addition to routine care, patients in the acupressure group received 8-min acupressure from the Zhongwan (CV12), Guanyuan (CV4) and Tianshu (ST25) acupoints once a day for 4 weeks. The outcomes included Defacationa Diary (DD), Visual Analog Scale Questionnaire (VASQ) and Patient assessment of constipation quality of life questionnaire (PAC-QOL).
Results

DD scores obtained by the acupressure and the control groups. There was a statistically significant difference between the acupressure and control groups in terms of stool consistency (2.22 ± .49 vs 1.80 ± .55) (p = 0.001), straining (1.98 ± .71 vs 2.91 ± .37) (p = 0.001), incomplete evacuation (0.37 ± .29 vs 0.61 ± .43) (p = 0.001), stool amount (0.93 ± .14 vs .95 ± .20) (p = 0.001) and the number of defecations (0.70 ± .22 vs 0.46 ± .29), (p = 0.001) measured at the fifth week. Besides, with the exception of stool amount, there was a statistically significant increase in the DD scores obtained by the acupressure group between the first and the fifth weeks. Inter-group comparison of the pre-test and post-test scores showed that acupressure group obtained statistically significantly higher scores from the PAC-QOL (p = .0001).
Conclusions

Findings of this trial suggested that 4-week acupressure was an effective way to improve the quality of life and reduce both subjective and objective constipation symptoms in patients with opioid-induced constipations.
A 2.45 GHz FSS Loaded Rectifying Antenna
Authors: PATTAPU UDAYABHASKAR , Das Sushrut 
Published: September 2021

Abstract
In this paper the development of a rectenna system has been presented for 2.45 GHz wireless power transfer application. The receiving element of the rectenna (or the antenna) has been designed to possess spurious free response at least up to 10 GHz to improve the RF-DC conversion efficiency. It was found that the gain of the antenna is not sufficient for rectenna application. Therefore, to improve the gain of the antenna, it has been loaded with an angle and polarization insensitive FSS. The FSS loaded antenna achieved 7.7 dB gain, 85% radiation efficiency, and single operating band at 2.45 GHz; which is suitable for developing a rectenna for wireless power transfer. To convert the received RF energy into DC voltage a 2.45 GHz matched rectifier circuit has been designed. L-type matching network has been used to match the complex rectifier impedance with the 50 Ω antenna impedance. 1.52 V output voltage was obtained for 7 dBm input power and 3 kΩ load. Achieved maximum efficiency is 66.13% for 1.1 mW received power. It has been shown that the FSS loading of the antenna has the capacity of drastically improve the efficiency of the rectenna system.
Diagnostic Fluid Biomarkers in Alzheimer’s Disease: Blood and Cerebrospinal Fluid
Authors: Park Jung Eun , Gunasekaran Tamil Iniyan , Cho Yeong Hee , Choi Seong-Min , Song Min-Kyung , Cho Soo Hyun , Kim Jahae , Song Ho-Chun , Choi Kyu Yeong , Lee Jang Jae , Park Zee-Yong , Song Woo Keun , Jeong Han-Seong , Lee Kun Ho , Lee Jung Sup , Kim Byeong C. 
Published: September 2021

Abstract
Background: Potential biomarkers for Alzheimer’s disease (AD) include amyloid β1-42 (Aβ1-42), t-Tau, p-Tau 181 , neurofilament light chain (NFL), and neuroimaging, but the feasibility of using these for the diagnosis and monitoring of AD has not been reported. Therefore, further development of these biomarkers is essential.Methods: We measured NFL and Aβ1-42 concentrations in CSF and plasma samples from 136 participants and performed correlation analysis to evaluate the utility of these biomarkers for early diagnosis and monitoring of disease progression in AD spectrum.Results: With disease progression, concentrations of NFL increased, and those of Aβ1-42 were decreases. The plasma and CSF values of NFL/Aβ1-42 were strongly correlated (r = 0.558). In addition, the plasma value of NFL/Aβ1-42 was strong correlated with hippocampal volume/ICV ( r = 0.409). In the early stage of AD, the plasma_NFL/Aβ1-42 was associated with higher diagnostic accuracy than were the individual biomarkers. Moreover, in preclinical AD, plasma_NFL/Aβ1-42 changed more rapidly than did either the t-Tau or the p-Tau181 values measured in the CSF.Conclusions: Taken together, our findings highlight the utility of plasma_NFL/Aβ1-42 as a biomarker for early diagnosis and monitoring of disease progression in AD spectrum.
Comprehensive sexuality education to reduce pregnancy and STIs in adolescents in the United States: A systematic review and meta-analysis
Authors: Bordogna Amy L. 
Published: September 2021

Abstract
Background.

The United States has a higher rate of teen pregnancy than any other developed country with 30% of American girls becoming pregnant before the age of 20. Laws regarding the inclusion and content of sexuality education vary across the country, which are associated with differences in pregnancy and sexually transmitted infection (STI) rates between states. This systematic review aims to determine whether comprehensive sexuality education (CSE) is more effective than abstinence-only or no sexuality education at reducing teenage pregnancy. Secondary objectives include analyzing the effect of CSE on STI incidence, sexual activity, safe-sex behaviors, and social discomfort.
Methods.

We searched MEDLINE (PubMed), EMBASE (Ovid), Cochrane Central Register of Controlled Trials, and Scopus for studies published from 1990–2021. Additionally, we searched ClinicalTrials.gov and Google Scholar and manually searched reference lists of included papers.
Results.

Twenty-nine studies met our inclusion criteria. Only seven included pregnancy as an outcome, with three fitting our meta-analysis criteria. There was a decrease in pregnancy rates for participants in the CSE intervention compared to the control (n = 3, risk ratio = 0.89, 95%CI 0.79- 1.00, I2 = 0%). Fifteen of 21 studies reporting safe-sex behaviors, 8 of 24 reporting sexual activity, and 0 of 3 reporting STI rates found statistically significant results favoring CSE. In the narrative synthesis, we found an increase in safe-sex behaviors, specifically condom use, in adolescents receiving CSE compared to no intervention.
Conclusions.

CSE is likely to reduce pregnancy rates; however, there was limited data available on this outcome. CSE increased safe-sex behaviors but did not have a notable impact on sexual activity or STIs. Future research should include the effects of CSE on social discomfort as well as more studies comparing CSE to abstinence-only education. This review can serve as evidence for the implementation of CSE in the US.
Influence Analysis of Environmental Information Disclosure Impact on Green Economy Development: An Exploratory Study Based on fsQCA
Authors: xiong qiang , Sun Dan 
Published: September 2021

Abstract
Increasing environmental degradation has forced policymakers to include sustainability in the economic growth agenda. Green finance has attracted the attention of policymakers and the industry, but the impact of green finance on social and environmental sustainability has not been confirmed. This study using the panel data of 30 Chinese provinces to investigate the relationship between green finance and environmental degradation. The fuzzy set qualitative comparative analysis (fsQCA) method is utilized for analyzing the mixed effect of green finance on the patch release behavior of CO2 emissions. These factors include vulnerability severity level, attention degree, quantity impact and attack path. The results show that exogenous demand factors including attention and attack type have auxiliary effects when endogenous demand factors including severity and popularity exist as the core antecedent conditions among green finance and environmental degradation. Finally, the policymakers should encourage financial technology to actively participate in environmental protection initiatives that promote green consumption while minimizing the systemic risks caused by financial technology.
Prevalence and factors associated to depression among Debrebirhan University students: a cross-sectional study
Authors: Tamene Marishet Agumasie , Dagne Biruk 
Published: September 2021

Abstract
Background:

Undiagnosed depression among university students has an adverse effect on the wellbeing and academic performance of students. This study aimed to assess the prevalence of depression and associated factors among Debre Birhan university students.
Methodology:

Institutional based cross-sectional study design is conducted in Debre Birhan University from April to June 2013 E.C. Three hundred sixty nine students participated in this study which was selected by simple random sampling technique. Data were collected by using a self-administered PHQ-9 standard depression questionnaire. First the data was entered into in Epidata 3.1 and then was exported to SPSS version 20 for analysis. Associated factors were identified using binary logistic regression and variables with a p-value < 0.05 were declared as statistically significant factors with the outcome variables.
Result:

All of the study subjects were between ages 18 and 33 with a mean age of 22.65 9 ± 2.78. The overall prevalence of depression is 17.1%. Among this according to PHQ-9 scores cut scores, 161(43.6 %) scored as normal (0–4), 145(39.3%) scored as mild (5–9), 53(14.4%) scored as moderate (10–14), 4(1.1%) scored as moderately severe (15–19) and 6(1.6%) students scored as sever (> 20). In multivariate analysis being female AOR = 9.28[3.47–24.81], academic year AOR = 0.236[0.059–0.936], smoking 26.3[9.33–74.1] and alcohol use AOR of 2.62[0.95–7.21] are significantly associated with depression.
Conclusion and recommendation:

This study found a considerable proportion of undergraduate students with depression. Higher institutions need to pay special attention to students especially those who are female, junior students, smokers and alcohol users.
COSFI-RIMAC: A Cooperative Short Frame Identifier Receiver Initiated MAC protocol for Wireless Sensor Network
Authors: Goudjil Lakhdar , Semchedine Fouzi 
Published: September 2021

Abstract
Power consumption is the most important factor to evaluate the performance of Wireless Sensor Networks (WSNs). Most sensor network Medium Access Control (MAC) protocols operate on the basis of a duty cycle mechanism. The asynchronous receiver initiated MAC duty cycle protocols are popular due to their relatively higher energy efficiency. However, recent advances harnessing the benefits of cooperative communication has become one of the solutions of MAC duty cycle protocol. In this article, we improve the RI-MAC protocol by introducing a short frame identifier to notify the sender when the receiver wakes up. This resolution reduces idle listening, which increases energy performance. When the sender node receives a short frame identifier, it cooperates with neighboring senders, which minimizes collisions.Our protocol is called: a Cooperative Short Frame Identifier Receiver Initiated MAC protocol, COSFI-RIMAC is an asynchronous MAC protocol cooperative service cycle initiated by the receiver. The simulation result on the NS2 simulator shows that the COSFI-RIMAC mechanism reduces power consumption, produces minor latency and increases the rate of packet delivery.
Two-transition-metal water oxidation catalysts. Faster rates via electronic structure tuning
Authors: Hill Craig , Tao Meilin , Yin Qiushi , Kaledin Alexey , Uhlikova Natalie , Chen Yu-Sheng , Lian Tianquan , Geletii Yurii , Musaev Djamaladdin , Bacsa John 
Published: September 2021

Abstract
Mixed 3d-metal oxides are some of the most promising water oxidation catalysts (WOCs), but it is very difficult to know the active site structures and thus structure-catalytic activity correlations at the molecular level in such insoluble materials. This study reports a molecular water oxidation catalyst, [Co2Ni2(PW9O34)2]10- (Co2Ni2P2), that constitutes a molecular model of the heterogeneous WOC, cobalt-nickel oxide. Both Co2Ni2P2 and its isostructural analogue, [Co4(PW9O34)2]10- (Co4P2), have the same CoO5(H2O) active sites but Co2Ni2P2 is an order of magnitude faster than Co4P2. Co2Ni2P2 is prepared by a new synthesis, and both the location and percent occupancy of Co and Ni in Co2Ni2P2 (Co outside and Ni inside the central belt are >97% for each) is confirmed by multiwavelength synchrotron X-radiation anomalous dispersion scattering (synchrotron XRAS), a technique applied for the first time to such complexes. Density functional theory (DFT) studies predicated and reveal that Co4P2 and Co2Ni2P2 have greatly altered frontier orbitals, while stopped-flow kinetic studies and DFT calculations indicate that water oxidation by both complexes follows analogous multi-step mechanisms, including Co-OOH formation, with the energetics of most steps being lower for Co2Ni2P2 than for Co4P2.
A machine learning approach to identify psychological factors driving vaccine hesitancy in high income countries
Authors: Lincoln Tania , Schlier Björn , Strakeljahn Felix , Gaudiano Brandon , So Suzanne , Kingston Jessica , Morris Eric , Ellett Lyn 
Published: September 2021

Abstract
Understanding factors driving vaccine hesitancy is crucial to vaccination success. We surveyed adults (N = 2510) from February to March 2021 across five sites (Australia = 502, Germany = 516, Hong Kong = 445, UK = 512, USA = 535) using a cross-sectional design and stratified quota sampling for age, sex, and education. We assessed willingness to take a vaccine and a comprehensive set of putative predictors. Predictive power was analysed with regression analyses and machine learning algorithms. Only 57.4% of the participants indicated that they would definitely or probably get vaccinated. A parsimonious machine-learning model could identify vaccine hesitancy with high accuracy (i.e. 83% sensitivity and 82% specificity) using 10 variables only. The most relevant predictors were vaccination conspiracy beliefs, paranoid concerns related to the pandemic, COVID anxiety, high perceived risk of infection, low perceived social rank, lower age, and female gender. Campaigns seeking to increase vaccine uptake need to take mistrust as the main driver of vaccine hesitancy into account.
Robust and sparse Dual Tree Complex Wavelet Transform-based Twin Support Vector regression for dense 5G InH Communications
Authors: charrada anis , Samet Abdelaziz 
Published: September 2021

Abstract
A robust and sparse Twin Support Vector Regression based on Dual Tree Discrete Wavelet Transform algorithm is conceived in this paper and applied to 28, 38, 60 and 73-GHz LOS (Line-of-Sight) wireless multipath transmission system in 5G Indoor Hotspot (InH) settings (simple, semi-complex and complex conference rooms) under small receiver sensitivity threshold. The algorithm establishes a denoising process in the learning phase based on Dual Tree Discrete Wavelet Transform (DT-CWT) which is suitable for time-series data. Additionally, the Close-In (CI) free space reference distance path loss model is analyzed and the large-scale propagation and probability distribution functions are investigated by determining the PLE (Path Loss Exponent) and the standard deviation of Shadow Factor (SF) for each InH scenario under consideration. Performance are evaluated under twelve (12) configuration scenarios, according to three criteria: mobility (0/3mps), receiver sensitivity threshold (-80/-120 dBm) and type of the InH area (simple, semi-complex and complex conference room). Experimental results confirm the effectiveness of the proposed approach compared to other standard techniques.
Intravenous insulin administration preparation for myocardial 18F-fluorodeoxyglucose viability imaging has the potential to reduce radiation exposure dose
Authors: Chen Yangchun , Wang Qingqing , Huang Peihao , Wang Yuehui , Chen Yuxuan , Zhuo Huilin , Dai Ruozhu , Wang Huoqiang 
Published: September 2021

Abstract
Purpose

This study aimed to identify and validate the optimal 18F-FDG activity and acquisition time for cardiac viability imaging with intravenous insulin administration based on a fixed 18F-FDG activity.
Methods

Cardiac positron emission tomography (PET) images from 30 patients with coronary artery disease (CAD) were retrospectively reconstructed into 900, 360, 180, 90, and 45 s durations. An optimal product of the maximum standardized uptake value (SUV) of the myocardium and segmental uptake (SU) and acquisition time (MSAT) was determined through a receiver operating characteristic curve. The optimal acquisition time (OAT) was equal to MSAT divided by mean SUV of the myocardium (MyoSUV) and validated in another 26 patients with CAD.
Results

The MyoSUV, mean SUV of the blood, SU, and their biases on reconstructed image durations of 90, 180, and 360 s were equivalent to those on an image duration of 900 s. The optimal MSAT was 848.2. In the validation group, the OAT was 129 ± 76 s (95% confidence interval, 99–160), approximately one-third of the usual acquisition time. The MyoSUV and SU were equivalent for the difference (0.15 ± 0.21, P < 0.001; −0.01 ± 0.03, P < 0.001) between PET image duration of OAT and 600 s (7.71 ± 3.01 vs. 7.56 ± 2.94, 67.1 ± 15.4% vs. 67.7 ± 15.6%).
Conclusion

Intravenous insulin administration preparation has the potential to reduce radiation exposure and acquisition time of cardiac 18F-FDG viability imaging without losing the accurate measurement of MyoSUV and SU when reaching an OAT.
Migration Law of Atrazine During Freezing of Water
Authors: Zhang Yan , Zhao Wanli , Yu Aixin , Liu Yucan , Ren Fangyun , Zhao Tongguo , Liu Tongshuai 
Published: September 2021

Abstract
To explore the migration law of atrazine during the freezing process, an indoor simulated freezing experiment was carried out. The distribution coefficient (K) was used to characterize the migration ability of atrazine and explore the effects of freezing thickness, freezing temperature, and initial concentration on the migration of atrazine between ice and water. The research results showed that the concentration relationship between the ice and water phases was: ice < water before freezing < water under the ice. This indicates that atrazine migrated to the water under the ice during the freezing process in our experiment. The K value decreased as the ice thickness, freezing temperature, and initial concentration increased; thus, the greater the ice thickness, the higher the freezing temperature, the greater the initial atrazine concentration, and the greater the ability of atrazine to migrate to the water under the ice. This study provides a reference for managing natural waterbodies in high-latitude and high-altitude environments during the freezing period.
Nurses Lack of Knowledge On Inhaler Devices In China: A Cross-Sectional Study
Authors: Xie Ning , Zheng Zheng , Yang Qilian , Li Man , Ye Xiaofen 
Published: September 2021

Abstract
Background: To know the knowledge on inhaler devices in medical staff, this study surveyed knowledge of inhaled therapy and the use of inhaler devices in nurses in China.Methods: 1831 nurses were selected to survey on a new self-designed questionnaire online. The questionnaire has 11 questions, including the storage location of the inhaler devices, steps of using the inhaler device, and the common errors when using various devices, etc. Results: Among the 1831 participants, 816(44.57%), 122(6.66%) and 893(48.77%) nurses worked in community hospital, secondary hospital and tertiary hospital respectively. Adequate knowledge of inhaler devices was demonstrated by nurses working in community hospital(20.10%)、Secondary hospital(8.2%) and Tertiary hospital(13.1%). 27.70% nurses in community hospital knew operational key points in using inhaler compared to in secondary hospital (15.57%) and tertiary hospital (23.18%) P<0.01. Only 9.5%-26.00% of participants chosen correct answers about the ten questions about the use of inhaler. Question six (Which of the following is the wrong option when using Ellpta?) was the one with the highest percentage of correct answers (26.00%). The question with lowest rate of correct answers (9.50%) was question 3 (What are the main points that need to be followed when using DPI?). The most people of correct answers number is Ellpta(26.00%) and the least is Respimat(10.32%). Conclusion: The focus on community hospitals has some results in China. However, knowledge on inhaler devices should be continued to strengthen among nurses in hospital. It is necessary to create training opportunities for nurses to increase their awareness and knowledge of chronic respiratory diseases management.
Undernutrition, Food Insecurity and Associated Factors among Adult HIV Positive people on HAART in Public Health Facility in Oromia Special Zone Surrounding Finfinne, Oromia, Ethiopia.
Authors: Neme Desalegn , Bikila Haile , Tesfaye Tariku , Desalegn Markos , Kaba Zalalem 
Published: September 2021

Abstract
Background: Malnutrition is resulted from inequalities in nutrients intake and body demands. People living with Human Immunodeficiency virus (PLHIV) are more vulnerable to malnutrition, due to opportunistic infection, metabolic disorder, and increased need of energy during infection. Worldwide, over 800 million people are chronically undernourished. The dual burden in areas of severe food insecurity and Human Immunodeficiency virus (HIV) epidemic are highly contributing to morbidity and mortality of people living with HIV, especially in developing countries particularly Sab- Saharan Africa is considered as home of malnutrition and food insecurity. The major problem of PLHIV in Ethiopia is under nutrition and its complication. Objective: This study aimed to assess magnitude of under nutrition, food insecurity and associated factors among adult clients on ART attending ART clinic, at public health facilities, Oromia regional states central Ethiopia Method: An institution based cross-sectional study was conducted among adult PLHIV and on highly active antiretroviral therapy(HAART) attending public health facility in Oromia Special Zone Surrounding Finfinne (OSZSF) was conducted from August 2020 to May 2021. A systematic sampling was applied for sample selection. A pre tested semi structured questionnaire was used to collect data. Bivariate and multivariable analysis also employed to identify the presence, strength, direction of association and other confounding. After calculating for both first objective (prevalence of under nutrition) and second objective or factors associated with under nutrition the maximum sample size 305 was selected for this study.Result: The prevalence of under nutrition was 22.4% and house hold food insecurity was also high in current study 54.3%. Factors associated with under nutrition among participants were absence of ration (AOR=0.42, 95%CI: 0.0-0.9), World health organization clinical stage II, III and VI (AOR= 6.8, 95%CI: 2.5-18.6) and household food in secure (AOR=0.51, 95%CI: 0.27-0.95) while literacy status primary and less (AOR=2.24, 95%CI: 1.1-4.6), household average monthly income <2250 Ethiopian birr (AOR=0.41, 95%CI:0.21-0.8) and meal frequency less or equal to two (AOR=4.14, 95%CI:1.3-13.46).Conclusion and recommendation: This study finding reveals high prevalence of under nutrition and HH food insecurity results in disturbing the success of the program, thus Comprehensive care and support bio-medical and inter-sectorial collaboration is suggested for alleviating the problem.