bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effect of Habitat Structural Complexity on Gastropods in Anarid Mangrove Wetland
Authors: Ebadzadeh Haniyeh , Shojaei Mehdi Ghodrati , Seyfabadi Jafar 
Published: December 2021

Abstract
Structural complexity of mangrove forests are thought to provide critical habitats for a variety of invertebrates. We studied the influence of mangrove structure and seasonality on the gastropod diversity in the extreme mangrove ecosystem of the Persian Gulf. Sampling was conducted in two successive years (February and June 2018, February and June 2019) at two mangrove habitats i.e., pneumatophore zone and mudflats. The communities were characterized by the dominance of specific taxa and the comparably low species richness. In total, 18 taxa were identified, including 14 species occurring in the mangrove forest and 16 species in the mudflats. Assimineidae dominated the community in both mangrove habitats. Mean density of gastropods was 1.5-fold higher in the pneumatophore zone (86.12±135.21 ind.m-2) than in the mudflats (54.33±108.69 ind.m-2). Species such as Haminoea vitrea, Peronia verruculata, Assiminea mesopotamica and Platevindex tigrinus were found to benefit from the presence of pneumatophores, which highlights the importance of local habitat complexity. Gastropod communities varied significantly between the habitats, but there was little difference in the community structure between seasons. Distance-based linear models revealed that total organic carbon and total organic nitrogen best explained the variation in gastropods community structure.
Prevalence and Correlates of Pregnancy Self-Testing Among Pregnant Women Attending Antenatal Care in Western Kenya
Authors: Nganga Nina Njeri , Dettinger Julia , Kinuthia John , Baeten Jared , John-Stewart Grace , Gómez Laurén , Ochieng Ben , Marwa Mary , Mugwanya Kenneth , Mugambi Melissa , Pintye Jillian 
Published: December 2021

Abstract
In sub-Saharan Africa little is known about how often women use pregnancy self-tests or characteristics of these women despite evidence that pregnancy self-testing is associated with early antenatal care (ANC) initiation. Understanding the characteristics of women who use pregnancy self-tests can facilitate more targeted efforts to improve pregnancy testing experiences and entry into the ANC pathway. We conducted a cross-sectional survey among pregnant women enrolling in a pre-exposure prophylaxis (PrEP) implementation study to determine the prevalence and factors associated with pregnancy self-testing among women in western Kenya. Overall, in our study population, 17% of women obtained a pregnancy self-test from a pharmacy. Pregnancy test use was higher among employed women, women with secondary and college-level educated partners, and women who spent 30 minutes or less traveling to the maternal and child health (MCH) clinic. The most reported reasons for non-use of pregnancy self-tests included not thinking it was necessary, lack of knowledge, and money to pay for the test. Future research should focus on understanding the knowledge and attitudes of women toward pregnancy self-testing as well as developing community-based models to improve access to pregnancy testing and ANC.
Using Molecular Weight-Based Fluorescent Detector to Characterize Dissolved EffluentOrganic Matter in Oxidation Ditch with Algae
Authors: Hidayah Euis Nurul , Cahyonugroho Okik Hendriyanto , Sulistyo Elita Nurfitriyani , Karnangingroem Nieke 
Published: December 2021

Abstract
Implementation microalgae has been considered for enhancing effluent wastewater quality. However, algae can cause environmental issues due to algae released extracellular organic matter, algal organic matter, instead of bacteria-derived organic matter in the biological process. The objectives of this study are to investigate the characteristics of dissolved effluent organic matter as algal-derived organic and bacteria-derived organic during the oxidation ditch process. Experiments were conducted in the oxidation ditch without algae, with Spirulina platensis and Chlorella vulgaris. The results showed dissolved effluent organic matter increased into higher dissolved organic carbon, more aromatic and hydrophobic than that before treatment. Fluorescence spectroscopy identified two component, namely aromatic protein-like at excitation/emission 230/345 nm and soluble microbial products-like at 320/345 nm after treatment, instead of fulvic acid-like at 230/420 nm and humic acid-like at 320/420 nm in raw wastewater. Fractionation of dissolved organic fluorescence based on average molecular weight cut-offs (MWCOs) has obtained that fractions aromatic protein-like, fulvic acid-like, humic acid-like, and soluble microbial products-like has respectively a high MWCOs 50,000 Da, a high to low MWCOs <1650 Da, medium MWCOs 1650 Da to low MWCOs. Biological oxidation ditch under symbiosis algal-bacteria generated humic acid-like and fulvic acid-like with a higher MWCOs than oxidation without algal. The quality and quantity of dissolved effluent organic matter in oxidation ditch algal reactor has been significant affected by algal-bacteria symbiotic.
Rapidly Spreading Deep Dissecting Hematoma Occurring One Month After A Minor Trauma: A Case Report.
Authors: Hamdan Rémy , Zwetyenga Narcisse , Macheboeuf Yvan , Ray Patrick 
Published: December 2021

Abstract
Background: Deep dissecting hematoma (DDH) is a rapidly extending blood collection that splits the hypodermis from muscle fascia, constituting a medical surgical emergency. The natural history of this condition includes trauma (even minor physical injury) shortly before onset of the lesion, occurring in a patient with advanced dermatoporosis. A delay of several weeks between the appearance of a superficial haematoma following a minor trauma and its sudden decompensation into a rapidly spreading DDH has been scarcely mentioned in the medical literature. Case presentation: We report the admission of a 70-year-old woman under anticoagulation to the emergency department of our hospital for the sudden appearance of a rapidly evolving hematoma one month after a negligible trauma to the right leg. A complete skin examination revealed clinical signs (spontaneous superficial skin haematomas, lacerations, wrinkles, stellate pseudo-scars) of advanced dermatoporosis, especially on the forearms. The initial biological testing disclosed an International Normalized Ratio of 3.15. The clinical aspect of the haematoma, its rapid extension and the cutaneous signs of dermatoporosis on the forearms allowed the diagnosis of DDH. Bedside ultrasound examination was used to eliminate differential or additional diagnoses and to assess the main features of the hematoma (dimensions, existence of blood supply). Due the extent of the lesion and the risk of extended skin necrosis, surgical debridement and hematoma drainage were performed. The operative report confirmed the diagnosis of DDH. Wound healing was obtained spontaneously after three months. Conclusion: DDH is the most serious complication of dermatoporosis. Given its rapid horizontal extension and the risk of skin necrosis it induces, DDH is a medical-surgical emergency and must be diagnosed early. This observation emphasises that in patients with severe dermatoporosis, on the occasion of a Vitamin K Antagonist overdose, a limb-threatening DDH can develop suddenly, even several weeks after a minor impact.
Is There a Benefit of Antenatal Corticosteroid When Given &lt; 48 Hours Before Delivery?
Authors: Siegler Yoav , Justman Naphtali , Bachar Gal , Lauterbach Roy , Zipori Yaniv , Khatib Nizar , Weiner Zeev , Vitner Dana 
Published: December 2021

Abstract
Objective
We assessed the association between a short Antenatal Corticosteroid Administration-to-Birth Interval and neonatal outcome.
Study design:
A retrospective study between 2010- 2020. Eligible cases were singleton preterm live-born neonates born between 24 0/7 and 33 6/7 weeks of gestation and were initiated an ACS course of Betamethasone. We divided the first 48 hours following 1st ACS administration to four-time intervals and compared each time interval to those born more than 48 hours following ACS administration. The primary outcome was a composite of adverse neonatal outcome, including neonatal mortality or any major neonatal morbidity.
Results
A total of 200 women gave birth less than 48 hours from receiving the first betamethasone injection, and 172 women gave birth within 2-7 days (48-168 hours) from ACS administration. Composite adverse neonatal outcome was higher for neonates born less than 12 hours from initial ACS administration compared to neonates born 2-7 days from first betamethasone injection (55.45% vs. 29.07%, OR 3.45 95% CI [2.02-5.89], p.value<0.0001). However, there was no difference in composite adverse neonatal outcomes between neonates born 12-48 hours following ACS administration and those born after 2-7 days. That was also true after adjusting for confounders.
Conclusions
12-24 hours following ACS Administration may be sufficient in reducing the same risk of neonatal morbidities as > 48 hours following ACS administration. It may raise the question regarding the utility of the second dose of ACS.
Ependymoma associated protein Zfta is expressed in immature ependymal cells but is not essential for ependymal development in mice
Authors: Herranz-Pérez Vicente , Nakatani Jin , Ishii Masaki , Katada Toshiaki , García-Verdugo Jose Manuel , Ohata Shinya 
Published: December 2021

Abstract
The fusion protein of uncharacterised zinc finger translocation associated (ZFTA) and effector transcription factor of tumorigenic NF-kB signalling, RELA (ZFTA-RELA), is expressed in more than two-thirds of supratentorial ependymoma (ST-EPN-RELA), but ZFTA’s expression profile and functional analysis in multiciliated ependymal (E1) cells have not been examined. Here, we showed the mRNA expression of mouse Zfta peaks on embryonic day (E) 17.5 in the wholemount of the lateral walls of the lateral ventricle. Zfta was expressed in the nuclei of FoxJ1-positive immature E1 (pre-E1) cells in E18.5 mouse embryonic brain. Interestingly, the transcription factors promoting ciliogenesis (ciliary TFs) (e.g., multicilin) and ZFTA-RELA upregulated luciferase activity using a 5’ upstream sequence of ZFTA in cultured cells. Zftatm1/tm1 knock-in mice did not show developmental defects or abnormal fertility. In the Zftatm1/tm1 E1 cells, morphology, gene expression, ciliary beating frequency and ependymal flow were unaffected. These results suggest that Zfta is expressed in pre-E1 cells, possibly under the control of ciliary TFs, but is not essential for ependymal development or flow. This study sheds light on the mechanism of the ZFTA-RELA expression in the pathogenesis of ST-EPN-RELA: Ciliary TFs initiate ZFTA-RELA expression in pre-E1 cells, and ZFTA-RELA enhances its own expression using positive feedback.
The Effects of a Combination of 3D Virtual Reality and Hands-on Horticultural Activities on Community-dwelling Older Adults’ Mental Health: A Quasi-Experimental Study
Authors: Fan Ching-Chih , Choy Cheuk-Sing , Huang Chiu-Mieh , Chih Po-Sheng , Lee Chia-Chiang , Lin Fen-He , Guo Jong-Long 
Published: December 2021

Abstract
Background: Aging societies are of public health concern worldwide. It is critical to develop strategies that harness technology to enhance older adults’ mental health.Methods: This study aimed to explore the effects of a combination of 3D virtual reality (VR) and hands-on horticultural activities on the mental health of community-dwelling older adults. The study used a quasi-experimental design. A total of 62 community-dwelling older adults were recruited and assigned to the experimental (n=32) and comparison groups (n=30). The members of the experimental group participated in an 8-week intervention program. Participants of both groups completed before-and-after intervention measurements for outcome variables that included perceived self-esteem, depression, isolation, mastery and achievement motives, which were analyzed using the generalized estimating equation (GEE). Results: GEE analyses indicated that the experimental group showed significant post intervention improvements in scores for self-esteem (β=1.66, P= .015), isolation (β=-0.96, P= .008), mastery (β=1.04, P= .042), and achievement motives (β=1.30, P=.034) compared to the control group.Conclusions: This study found beneficial effects of a combination of three-dimensional virtual reality and hands-on horticultural activities on community-dwelling older adults’ mental health. These findings suggest that future implementations of this program on a large scale could improve the mental health of older adults. Trial Registration: The study was posted in the www.clinicaltrials.gov (NCT05087654) on 21/10/2021. It was approved by the Institutional Review Board of En Chu Kong Hospital and performed in accordance with the Declaration of Helsinki.
Postoperative Drainage for 6, 12, or 24 Hours After Burr-Hole Evacuation of Chronic Subdural Hematoma in Symptomatic Patients (DRAIN-TIME 2): Study Protocol for a Nationwide Randomized Controlled Trial
Authors: Grønhøj Mads Hjortdal , Jensen Thorbjørn Søren Rønn , Sindby Ann Kathrine , Miscov Rares , Hundsholt Torben , Brabant Birgit , Bjarkam Carsten Reidies , Bergholt Bo , Fugleholm Kåre Buch , Rom-Poulsen Frantz 
Published: December 2021

Abstract
Background: Chronic subdural hematoma (CSDH) is a common acute or subacute neurosurgical condition, typically treated by burr-hole evacuation and drainage. Recurrent CSDH occurs in 5-20 % of cases and requires reoperation in symptomatic patients, sometimes repeatedly. Postoperative subdural drainage of maximal 48 hours is effective in reducing recurrent hematomas. However, the shortest possible drainage time without increasing the recurrence rate is unknown.Methods: DRAIN-TIME 2 is a Danish multi-center, randomized controlled trial of postoperative drainage time including all four neurosurgical departments in Denmark. Both incapacitated and mentally competent patients are enrolled. Patients older than 18 years, free of other intracranial pathologies or history of previous brain surgery, are recruited at time of admission or no later than 6 hours after surgery. Each patient is randomized to either 6, 12, or 24 hours of passive subdural drainage following single burr-hole evacuation of a CSDH. Mentally competent patients are asked to complete the SF-36 questionnaire. The primary endpoint is CSDH recurrence rate at 90 days. Secondary outcome measures include SF-36 at 90 days, length of hospital stay, drain-related complications, and complications related to immobilization and mortality.Discussion: This multi-center trial will provide evidence regarding shortest possible drainage time without increasing the recurrence rate. The potential impact of this study is significant as we believe that a shorter drainage period may be associated with fewer drain-related complications, faster mobilization, fewer complications related to immobilization, and shorter hospital stays—thus reducing the overall health service burden from this condition. The expected benefits for patients’ lives and health costs will increase as the CSDH patient population grows.Trial registration: ISRCTN15186366. https://doi.org/10.1186/ISRCTN15186366. Registered in December 2020 and updated in October 2021.This protocol was developed in accordance with the SPIRIT checklist and by use of the structured study protocol template provided by BMC Trials.
MULHER EMPREENDEDORA: FORTALECIMENTO DE PRÁTICAS DE EMPREENDEDORISMO E PARTICIPAÇÃO SOCIAL
Authors: Ferreira Tainara Lorêna dos Santos , Andrade Fábia Barbosa de 
Published: December 2021

O programa de extensão intitulado Mulher Empreendedora: garantindo espaço de construção do conhecimento, saberes e participação social na comunidade surgiu das necessidades das relações de gênero, em virtude do constante crescimento do empreendedorismo feminino. O objetivodo projeto foi discutir a experiência vivenciada pela equipe do programa durante o ano de 2014, cujo público-alvo foi constituído por mulheres gerentes de empresas, horteiras, empregadas das fábricas de costuras, catadoras de lixo e auxiliares de serviços gerais, em locais da comunidade urbana e rural do município de Santa Cruz, Rio Grande do Norte. Esse programa foi dividido em cinco ações de extensão, que se complementam: I) Capacitação de empresárias da cidade de Santa Cruz/RN: construção da cartilha educativa Conhecer para Empreender; II) Capacitação para resgate de saberes e práticas em mulheres horteiras com enfoque econômico, profissional e em saúde; III) Mulheres e cooperativismo: capacitação sobre produção com qualidade nas fábricas de costura de Santa Cruz/RN; IV) Capacitação em associações de moradores: o espaço político e de atuação de mulheres empreendedoras na zona urbana e rural; V) Biossegurança: capacitação de auxiliares de serviços gerais e catadores de lixo na coleta seletiva e manejo de resíduos. Estas atividades ocorreram em parceria com vários órgãos e instituições municipais públicas de Santa Cruz, bem como docentes, discentes e técnicos da Faculdade de Ciências da Saúde do Trairi/Universidade Federal do Rio Grande do Norte. Ressalta-se que o programa veio ao encontro das deficiências das mulheres no mercado de trabalho de modo a contribuir para o crescimento de sua autonomia, empreendedorismo e participação social na comunidade.
O PIBID/PEDAGOGIA E A GARANTIA DOS DIREITOS DE APRENDIZAGEM NAS DIVERSAS ÁREAS DO CONHECIMENTO
Authors: Monteiro Cristiane de Oliveira Correia , Tavares Isabelle Emily Ferreira de Souza , Da Rocha Rayanne Karolayne Silvestre , Dias Lidiana Oliveira da Silva , Santos Thalita da Silva , De Andrade João Maria Valença 
Published: December 2021

Este artigo apresenta alguns dos direitos de aprendizagem garantidos em diferentes áreas do conhecimento, durante as intervenções realizadas pelos projetos desenvolvidos no Programa Institucional de Bolsa de Iniciação à Docência (PIBID), subprojeto Pedagogia/ UFRN. Relata experiências vivenciadas nas turmas do 1° ano A e B do Ensino Fundamental da Escola Municipal Professora Emília Ramos, localizada no bairro de Cidade Nova (Natal, RN), a partir dos projetos A minha, a sua, a nossa cor e Repensando o lixo a partir da consciência ambiental. Os temas abordados nos projetos possibilitaram a garantia dos direitos de aprendizagem nas diversas áreas do conhecimento como o reconhecimento das semelhanças e diferenças existentes entre o/a aluno/a criança e os colegas e o reconhecimento dos problemas ambientais existentes na comunidade e sua relação com a qualidade de vida e saúde. A metodologia utilizada considerou a utilização de vídeos, histórias literárias, produção de obras de arte com materiais recicláveis, jogos, brincadeiras, aula-passeio e atividades explorando os eixos estruturantes de ensino da Língua Portuguesa. Tudo isso com a finalidade de garantir os direitos de aprendizagem relacionados ao processo de alfabetização. Como resultados alcançados, destacam-se a aquisição de valores como o respeito às diferenças e ao meio ambiente, partindo do eu, sua relação com o outro e com o espaço em que vivemos.
NO LIMIAR DO COTIDIANO ESCOLAR: AÇÕES FORMATIVAS COM O PIBID PARA A APROPRIAÇÃO DA LEITURA POR ALUNOS DE EJA
Authors: Soares Maria de Lourdes Gabriel Ferreira , Aldryncollen Dyego , Araújo Karolyne Cristina de Carvalho , De Andrade João Maria Valença 
Published: December 2021

Este artigo apresenta reflexão acerca de aspectos teóricos e práticos dos trabalhos desenvolvidos por bolsistas do Programa Institucional de Bolsa de Iniciação à Docência (PIBID), estudantes de Pedagogia da Universidade Federal do Rio Grande do Norte/UFRN, na Escola Municipal Profª Emília Ramos, Natal/ RN, Brasil, no ensino da modalidade Educação de Jovens e Adultos.A leitura é uma atividade do Sistema de Escrita Alfabético (SEA), que perpassa, inicialmente, pela decodificação, sendo essa a concretude e a finalidade da escrita. Em geral, o professor realiza as mediações de ensino e, ao avaliar, remete apenas ao processo da escrita. Tal fato expõea dificuldade em realizar intervenções direcionadas ao processo de apropriação da leitura. Decorre disso privilegiar a reflexão sobre oficinas pedagógicas para a apropriação do SEA, realizadas com estudantes bolsistas PIBID e com docentes, nos dias de estudo e de assessoramento, assim como nas atividades de planejamento. Essas oficinas foram propostas pela coordenação pedagógica da escola, a partir da preocupação com os resultados insatisfatórios da aprendizagem. Consistiram em uma forma de contribuir para a articulação entre teoria e prática, indispensável à ação educativa dos estudantes bolsistas e das professoras colaboradoras. Visou-se, também, um incremento na qualidade das intervenções junto aos alunos da escola. Seus resultados incidiram nos projetos desenvolvidos pelos bolsistas PIBID.Avaliações de professores e pedagogos sobre as ações para a apropriação da leitura por aluno da EJA vêm mostrando ser o PIBID uma ação coerente e viável, pois vincula conteúdos trabalhados com a prática social, fundamentação teórica com práticas docentes.
Gut Microbiota and Cardiovascular Disease: Symbiosis Versus
Dysbiosis
Authors: Manolis Antonis A. , Manolis Theodora A. , Melita Helen , Manolis Antonis S. 
Published: December 2021

:
The gut microbiome interacts with host physiology through various mechanisms,
including the cardiovascular (CV) system. A healthy microbiome has the ability
to process and digest complex carbohydrates into short-chain fatty acids (SCFA). These
SCFA function as signaling molecules, immune-modulating molecules, and energy
sources. However, when the microbiome is altered, it produces gut dysbiosis with overgrowth
of certain bacteria that may lead to overproduction of trimethylamine-N-oxide (TMAO)
from the metabolism of phosphatidylcholine, choline, and carnitine; dysbiosis also
leads to increased intestinal permeability allowing the microbiome-derived
lipopolysaccharide (LPS), a bacterial endotoxin, to enter the blood circulation, triggering
inflammatory responses. An altered gastrointestinal (GI) tract environment and microbiome-
derived metabolites are associated with CV events. Disrupted content and function
of the microbiome leading to elevated TMAO and LPS levels, altered bile acid
metabolism pathways, and SCFA production are associated with an increased risk of CV
diseases (CVD), including atherosclerosis, myocardial infarction, thrombosis, arrhythmias,
and stroke. Therapeutic interventions that may favorably influence a dysbiotic GI
tract profile and promote a healthy microbiome may benefit the CV system and lead to a
reduction of CVD incidence in certain situations. These issues are herein reviewed with a
focus on the spectrum of microbiota-related CVD, the mechanisms involved, and the potential
use of microbiome modification as a possible therapeutic intervention.
Comprehensive Review on Neuro-degenerative Type 3 DM
Authors: Chandarana Chandani V. , Roy Salona 
Published: December 2021

:
According to research, Alzheimer’s disease (AD) is considered a metabolic illness
caused by defective insulin signaling, insulin resistance, and low insulin levels in the brain. Type 3
diabetes has been postulated for AD because reduced insulin signaling has molecular and physiological
consequences that are comparable to type I and type 2 diabetes mellitus, respectively. The
similarities between type 2 diabetes and Alzheimer’s disease suggest that these clinical trials might
yield therapeutic benefits. However, it is important to note that lowering your risk of Alzheimer’s
dementia, whether you have diabetes or not, is still a multidimensional process involving factors
like exercise, smoking, alcohol, food, and mental challenges. The current aim is to show that the relationship
between T3D and AD is based on both the processing of amyloid-β (Aβ) precursor protein
toxicity and the clearance of Aβ, which are the results of impaired insulin signaling. The
brain’s metabolism, with its high lipid content and energy needs, places excess demands on mitochondria
and appears more susceptible to oxidative damage than the rest of the body. Current data
suggests that increased oxidative stress relates to amyloid-β (Aβ) pathology and the onset of AD.