bluuebunny/crossref_metadata_2025_split huggingface dataset:
The World Is Not Enough*: ethics in arbitration seen through the world of film
Authors: Rogers Catherine A 
Published: January 2021

Abstract
This article starts from the playful premise that if James Bond practiced law, it would be international arbitration. The article uses the 007 metaphor and the titles of James Bond films to examine the ethical challenges that confront various actors in international arbitration. The article argues that arbitration practitioners—as they tend to the needs of their clients, their organizations, their institutions, and their own professional goals—should look beyond their most immediate, short-term self-interest so their case does not become the billboard for some endemic problem or controversy in international arbitration. A modicum of foresight might have altered outcomes in some of arbitration's most disruptive cases and sensational cases—HEP v. Slovenia, Yukos, Einser, and RSM v. St. Lucia. The article concludes with a QUANTUM OF SOLACE—those professionals active in international arbitration have it within their power and have demonstrated a collective impulse to address problems through a determined self-reassessment and internal recalibration. In conclusion, it calls on international arbitration practitioners to make that collective impulse an express commitment, at TOMORROW NEVER DIES.
Study on the effect of Mongolian medicine Qiwei Qinggan Powder on hepatic fibrosis through JAK2/STAT3 pathway
Authors: Liang Jie , Yuan Hongwei , Xu Liping , Wang Feng , Bao Xiaomei , Yan Yuxin , Wang Haisheng , Zhang Chunyan , Jin Rong , Ma Lijie , Zhang Jianyu , Huri Lebagen , Su Xiaoli , Xiao Rui , Ma Yuehong 
Published: January 2021

ABSTRACT
This research aimed to evaluate the antihepatic fibrosis effect and explore the mechanism of Qiwei Qinggan Powder (QGS-7) in vivo and in vitro. Carbon tetrachloride (CCl4)-treated rats and hepatic stellate cells (HSCs) were used. QGS-7 treatment significantly improved the liver function of rats as indicated by decreased serum enzymatic activities of alanine aminotransferase, aspartate transaminase, and alkaline phosphatase. Meanwhile, the hydroxyproline of liver was significantly decreased. Histopathological results indicated that QGS-7 alleviated liver damage and reduced the formation of fibrosis septa. Moreover, QGS-7 significantly attenuated expressions of Alpha smooth muscle actin, Collagen I, Janus kinase 2 (JAK2), phosphorylation-JAK2, signal transducer and activator of transcription 3 (STAT3), phosphorylation-STAT3 in the rat hepatic fibrosis model. QGS-7 inhibited HSC proliferation and promoted it apoptosis. QGS-7 may affect hepatic fibrosis through JAK2/STAT3 signaling pathway so as to play an antihepatic fibrosis role.
bbeaR: an R package and framework for epitope-specific antibody profiling
Authors: Suprun Maria , Ellis Randall J , Sampson Hugh A , Suárez-Fariñas Mayte 
Published: January 2021

Abstract

Summary
Analysis of epitope-specific antibody repertoires has provided novel insights into the pathogenesis of inflammatory disorders, especially allergies. A novel multiplex immunoassay, termed Bead-Based Epitope Assay (BBEA), was developed to quantify levels of epitope-specific immunoglobulins, including IgE, IgG, IgA and IgD isotypes. bbeaR is an open-source R package, developed for the BBEA, provides a framework to import, process and normalize .csv data files exported from the Luminex reader, evaluate various quality control metrics, analyze differential epitope-binding antibodies with linear modeling, visualize results and map epitopes’ amino acid sequences to their respective primary protein structures. bbeaR enables streamlined and reproducible analysis of epitope-specific antibody profiles.

Availability and implementation
bbeaR is open-source and freely available from GitHub as an R package: https://github.com/msuprun/bbeaR; vignettes included.

Supplementary information
Supplementary data are available at Bioinformatics online.
Beyond the Meaning of Zines: A Case Study of the Role of Materiality in four Prague-Based Zine Assemblages
Authors: Hroch Miloš , Carpentier Nico 
Published: January 2021

AbstractThis article studies the role of the material in four Prague-based zines. The analysis is theoretically embedded in the model of the discursive-material knot, which is a non-hierarchical articulation of the discursive and the material, and it is contextualized by a reflection on post-digital culture, which allows revalidating the role of the material in zine production and distribution more. The case study combines the analysis of personal interviews and zine content with an ethnography of the production and distribution processes, including zine fairs. This analysis shows how the alternative media discourse, with its focus on particular aesthetics and amateurism, intersects with networks of bodies, spaces, paper and related objects, many different machines and scarce capitals. This allows arguing that the material is omnipresent in zine production and distribution, also in intermaterial and transmaterial ways, but also that zines then use the particularity of this material component to signify their cultural specificity.
Depoliticizing Politics: Egypt’s Media Boycotts in the Turkish Media
Authors: Kaptan Yeşim , Kraidy Marwan M 
Published: January 2021

Abstract
By focusing on public discourse about the 2013 Egyptian boycott of Turkish television series, this paper analyzes the rarely discussed “media boycott” phenomenon in media studies. By examining the discursive chasms of Turkish Press and entertainment media through a critical discourse analysis (CDA), we investigate how the Turkish dailies take a position to determine the boycotting issue to the public, and enquire into the politics around the boycotting discourse which created an illusion that markets are not embedded in political relations, which can be considered separate domains under capitalism. The concept we called “depoliticizing the politics” denotes that Turkish agents framed the boycott as a solely economic crisis by dismissing the conflict’s political dimension.
Association between Socioeconomic Status and Incidence of Community-Associated Clostridioides difficile Infection — United States, 2014–2015
Authors: Skrobarcek Kimberly A , Mu Yi , Ahern Jennifer , Basiliere Elizabeth , Beldavs Zintars G , Brousseau Geoffrey , Dumyati Ghinwa , Fridkin Scott , Holzbauer Stacy M , Johnston Helen , Kainer Marion A , Meek James , Ocampo Valerie L S , Parker Erin , Perlmutter Rebecca , Phipps Erin C , Winston Lisa , Guh Alice 
Published: January 2021

Abstract
We evaluated the association between socioeconomic status (SES) and community-associated Clostridioides difficile infection (CA-CDI) incidence across 2474 census tracts in 10 states. Highly correlated community-level SES variables were transformed into distinct factors using factor analysis. We found low SES communities were associated with higher CA-CDI incidence.
Waning Vaccine Effectiveness Against Influenza-Associated Hospitalizations Among Adults, 2015–2016 to 2018–2019, United States Hospitalized Adult Influenza Vaccine Effectiveness Network
Authors: Ferdinands Jill M , Gaglani Manjusha , Martin Emily T , Monto Arnold S , Middleton Donald , Silveira Fernanda , Talbot H Keipp , Zimmerman Richard , Patel Manish 
Published: January 2021

Abstract
We observed decreased effectiveness of influenza vaccine with increasing time since vaccination for prevention of influenza A(H3N2), influenza A(H1N1)pdm09, and influenza B/Yamagata–associated hospitalizations among adults. Maximum vaccine effectiveness (VE) was observed shortly after vaccination, followed by an absolute decline in VE of about 8%–9% per month postvaccination.
Prevalence, recognition and management of chronic kidney disease in Japan: population-based estimate using a healthcare database with routine health checkup data
Authors: Takeuchi Masato , Shinkawa Kanna , Yanagita Motoko , Kawakami Koji 
Published: January 2021

Abstract

Background
We aimed to update information on the prevalence of chronic kidney disease (CKD) in Japan. We also explored whether CKD was properly recognized and managed.

Methods
We used data from annual health checkups in 2017, compiling records for 5 million persons. These included laboratory results and were linked to healthcare utilization records via personal identifiers. CKD was defined as an estimated glomerular filtration rate &lt;60 mL/min/1.73 m2. The prevalence was compared with that in 2005. Healthcare utilization, including laboratory tests, disease coding and medication for comorbid diabetes mellitus (DM) and hypertension (HT), was used as an indicator for the recognition and management of CKD.

Results
Of the 761 565 records [median age 46 years (interquartile range 50–62)], CKD was found in 50 091 persons; the crude and age-adjusted prevalences were 63.1 and 71.8 per 1000 persons, respectively. CKD prevalence was significantly higher in 2017 than in 2005, with an increase of 14.1 per 1000 persons. Among persons with CKD, &gt;95% sought medical services and 64.6% received laboratory tests within 180 days of the checkup. However, the diagnostic code suggestive of CKD was recorded in only 23.2% of patients and prescriptions for DM and HT were found in 31.2% (1590/5096) and 36.7% (8081/22 019) of comorbid persons, respectively.

Conclusions
The prevalence of CKD in Japan has increased over the past decade. However, recognition of CKD is likely suboptimal and there is room to improve the management of comorbid DM and HT.
NLRP3 inflammasome as a key driver of vascular disease
Authors: Takahashi Masafumi 
Published: January 2021

AbstractNucleotide-binding oligomerization domain-like receptor family pyrin domain containing 3 (NLRP3) is an intracellular innate immune receptor that recognizes a diverse range of stimuli derived from pathogens, damaged or dead cells, and irritants. NLRP3 activation causes the assembly of a large multiprotein complex termed the NLRP3 inflammasome, and leads to the secretion of bioactive interleukin (IL)-1β and IL-18 as well as the induction of inflammatory cell death termed pyroptosis. Accumulating evidence indicates that NLRP3 inflammasome plays a key role in the pathogenesis of sterile inflammatory diseases, including atherosclerosis and other vascular diseases. Indeed, the results of the Canakinumab Anti-inflammatory Thrombosis Outcome Study trial demonstrated that IL-1β-mediated inflammation plays an important role in atherothrombotic events and suggested that NLRP3 inflammasome is a key driver of atherosclerosis. In this review, we will summarize the current state of knowledge regarding the role of NLRP3 inflammasome in vascular diseases, in particular in atherosclerosis, vascular injury, aortic aneurysm, and Kawasaki disease vasculitis, and discuss NLRP3 inflammasome as a therapeutic target for these disorders.
Large mixed-frequency VARs with a parsimonious time-varying parameter structure
Authors: Götz Thomas B , Hauzenberger Klemens 
Published: January 2021

SummaryIn order to simultaneously consider mixed-frequency time series, their joint dynamics, and possible structural change, we introduce a time-varying parameter mixed-frequency vector autoregression (VAR). Time variation enters in a parsimonious way: only the intercepts and a common factor in the error variances can vary. Computational complexity therefore remains in a range that still allows us to estimate moderately large VARs in a reasonable amount of time. This makes our model an appealing addition to any suite of forecasting models. For eleven U.S. variables, we show the competitiveness compared to a commonly used constant-coefficient mixed-frequency VAR and other related model classes. Our model also accurately captures the drop in the gross domestic product during the COVID-19 pandemic.
Quadruple episodes of takotsubo cardiomyopathy: a case report
Authors: Hiruma Takashi , Higuchi Ryosuke , Iguchi Nobuo 
Published: January 2021

Abstract

Background
Takotsubo syndrome (TTS) is characterized by transient left ventricular (LV) dysfunction, often preceded by emotional or physical trigger. The recurrence of TTS has been investigated, however, cases of multiple recurrences are scarcely reported.

Case summary
A 79-year-old woman was admitted to the hospital with the complaint of dyspnoea following emotional stress. Electrocardiogram showed terminal T-wave inversion with QT interval prolongation in anterior leads. Transthoracic echocardiogram revealed severe hypokinesis of mid- and apical-anterior segments. She was diagnosed with focal TTS. After 3 months, she complained of orthopnoea subsequent to upper-respiratory infection. Coronary angiography (CAG) depicted normal coronary arteries. She had recurrence of TTS with bi-ventricular dysfunction, and complicated cardiac collapse requiring intra-aortic balloon pumping. One month after the second episode, she had dyspnoea after herpes zoster infection. She was diagnosed with recurrence of focal TTS. After 4 months, she complained of central chest pain without evident trigger factors. CAG showed no coronary artery stenosis, and left ventriculography revealed mid-inferior and apical segment akinesis. She was diagnosed with the 4th occurrence of TTS.

Discussion
We describe the case of an elderly female experiencing quadruple episodes of TTS with various triggers, LV dysfunctions and severities in a short period of 10 months. Although multiple recurrences of TTS is rare, it can occur with variable trigger factors and patterns of myocardial dysfunction. An analysis of multiple recurrences could aid in clarifying the pathophysiology of TTS.
Effect of water stress on growth and dry matter distribution of four dryland species used in tree planting in the Sahel
Authors: Bayen Philippe , Lykke Anne Mette , Kagambèga François Wenemi , Bognounou Fidèle , Thiombiano Adjima 
Published: January 2021

AbstractWater stress is the most important factor limiting early survival and growth of seedlings in arid and semi-arid zones. Many woody species develop adaptive mechanisms in response to water stress. This study assesses survival rate, growth and dry matter distribution in response to water stress in four dryland species (Senegalia dudgeonii, Senegalia gourmaensis, Vachellia nilotica and Vachellia tortilis). A total of 240 seedlings (60 per species) were grown using a completely randomized block design with three replicates in each of three water treatments (control = 100 percent of field capacity; moderate water stress = 50 percent of field capacity; severe water stress = 25 percent of field capacity) with a 7 day watering frequency. Data were collected on seedling survival, height, collar diameter, leaf production and dry matter distribution. Survival rate of the four species was not affected by water stress. However, the morphological responses to water stress were significantly different between species. Water stress resulted in significant reductions in height and collar diameter, higher below-ground biomass and significant increase in shedding of leaves. Under water stress, S. dudgeonii, S. gourmaensis and V. tortilis invested more in root growth. The allocation pattern from above-ground to below-ground parts was found to be the main adaption to drought. In contrast, V. nilotica gave preference to above-ground development, which could be an indication that the seedlings are adapted to grow under severe water stress. The results confirm the interspecific genetic differences in growth and dry matter distribution among species. These variations in water stress response may be used as criteria for species selection for degraded land reforestation.
Southern Pine Beetle: Factors Influencing the Growth and Decline of Summer Infestations in East Texas
Authors: Hedden Roy L. , Billings Ronald F. 
Published: January 2021

Abstract
The influence of selected forest site and stand factors on the rate of expansion of individual infestations (spots) of southern pine beetle (Dendroctonus frontalis) was studied during the summer months of 1975-77 in east Texas. In small spots (≤20 active trees), further expansion seldom occurred, presumably due to an insufficient quantity and distribution of brood to perpetuate necessary pheromone production. Similarly, the proportion of spots that had declined to less than 20 active trees after 1 month (day 30) was inversely related to number of active trees at first visit (day 0). In expanding spots, the number of additional trees killed per day was significantly and positively correlated with number of active trees per spot and stand basal area. In addition, mean rates of summer spot growth varied among years in direct relation to areawide beetle population levels in east Texas which increased to outbreak levels and then collapsed over the 3-year study period. This emphasizes the need to include some measure of beetle population level and/or aggressiveness in future spot growth models. No correlation was found between number of brood trees per spot at the first visit and stand basal area at the spot origin. These findings support the following hierarchy of priorities for direct control: Priority 1--spots with &gt;100 active trees, even in sparse stands; Priority 2--spots with 20-100 active trees in high basal area stands; Priority 3--spots with 20-100 active trees in low basal area stands; Priority 4--spots with ≤20 active trees. During the summer, small spots, particularly those lacking freshly attacked trees (pheromone source), have a high probability of soon going inactive without control. Forest Sci. 25:547-556.
Controlled Moisture Stress to Improve Cold Hardiness and Morphology of Douglas-fir Seedlings
Authors: Blake John , Zaerr Joe , Hee Stephen 
Published: January 2021

Abstract
Nursery-grown seedlings of Douglas-fir (Pseudotsuga menziesii) were subjected to three levels of moisture stress between late July and the end of August. Measurements in October and December showed that mild stress of -5 to -10 bars significantly improved cold hardiness. In a second experiment, the effectiveness of the mild stress treatment decreased as the onset of the stress was delayed from mid-July until September 1. Furthermore, the earlier onset of stress decreased the height and shoot/root ratio, but increased the root weight and nitrogen content of the needles. For seedlings lifted in October, mild stress also decreased mortality from cold storage. Forest Sci. 25:576-582.
Ectomycorrhizal Inoculation of Containerized Douglas-fir and Lodgepole Pine Seedlings with Six Isolates of Pisolithus tinctorius
Authors: Molina Randy 
Published: January 2021

Abstract
Containerized Douglas-fir and lodgepole pine seedlings grown under lowered fertility were inoculated with vegetative mycelium from six isolates of the ectomycorrhizal fungus Pisolithus tinctorius. The isolates differed both culturally and in effectiveness as ectomycorrhizal inoculum. The percent of seedlings successfully inoculated and percent of feeder roots colonized differed significantly among the isolates. Analysis of variance, however, for seedling height, stem diameter, stem and root dry weights, and top/root ratio showed no significant differences between any inoculation treatment and controls for either tree species. This study reinforces the concept that a wide array of fungus ecotypes should be tested before a specific strain is selected for wide-scale nursery inoculations. Forest Sci. 25:585-590.
A Technique for Estimating Timber Value Based on Tree Size, Management Variables, and Market Conditions
Authors: Jackson David H. , McQuillan Alan G. 
Published: January 2021

Abstract
Based upon revealed market preferences for timber, the authors developed an empirical stumpage valuation model for three ranger districts of the Lolo National Forest. The equation suggests how tree diameter, volume per acre harvested, reproduction systems utilized, logging systems employed, and market conditions affect the selling value of timber. Increase in volume per acre harvested, the amount of a sale that is clearcut or tractor skidded, and increases in the real value of lumber all increase the amount bid for a timber sale. Likewise, the diameter mix included in a sale will affect bidding levels. Of particular importance is the method developed which shows the effect of the mix of tree diameters in each sale on sale value. Brief remarks concerning the use of the model conclude the paper. Forest Sci. 25:620-626.
Optimizing Thinning in Douglas-fir with Three-Descriptor Dynamic Programming to Account for Accelerated Diameter Growth
Authors: Brodie J. Douglas , Kao Chiang 
Published: January 2021

Abstract
Accelerated diameter growth as a result of thinning must be incorporated into dynamic programming analysis to account for reduced logging cost and increased income as the size of harvested material increases. A three state-descriptor model is necessary to do this, but a three-descriptor formulation encounters problems of rounding, storage, and computational efficiency. Techniques for overcoming these problems are outlined and applied in representative demonstrations of the model. Forest Sci. 25:665-672.
Chromosome-Level Genome Assembly and Annotation of a Sciaenid Fish, Argyrosomus japonicus
Authors: Zhao Linlin , Xu Shengyong , Han Zhiqiang , Liu Qi , Ke Wensi , Liu An , Gao Tianxiang 
Published: January 2021

Abstract
Argyrosomus japonicus is an economically and ecologically important fish species in the family Sciaenidae with a wide distribution in the world’s oceans. Here, we report a high-quality, chromosome-level genome assembly of A. japonicus based on PacBio and Hi-C sequencing technology. A 673.7-Mb genome containing 282 contigs with an N50 length of 18.4 Mb was obtained based on PacBio long reads. These contigs were further ordered and clustered into 24 chromosome groups based on Hi-C data. In addition, a total of 217.2 Mb (32.24% of the assembled genome) of sequences were identified as repeat elements, and 23,730 protein-coding genes were predicted based on multiple approaches. More than 97% of BUSCO genes were identified in the A. japonicus genome. The high-quality genome assembled in this work not only provides a valuable genomic resource for future population genetics, conservation biology and selective breeding studies of A. japonicus but also lays a solid foundation for the study of Sciaenidae evolution.
COMPUTERIZED MEIOTIC MAPPING IN ASPERGILLUS NIDULANS
Authors: Dorn Gordon L 
Published: January 2021

ABSTRACT
A computer system for the storage and processing of microbial meiotic data has been developed. Based on the language Fortran 4, the program retrieves relevant data and determines the order, map distances, and coefficient of coincidence for any three-gene group. Meiotic data from Aspergillus nidulans were used to test the program. A total of 61 three-gene sequences were processed, and the results were found to be compatible with the published values. The advantages and disadvantages of computer analysis for genetic analysis are discussed.