bluuebunny/crossref_metadata_2025_split huggingface dataset:
Versatility of use of fibrin glue in wound closure and vitreo-retinal surgery
Authors: Lopezcarasa-Hernandez Gabriela , Perez-Vazquez Jose-Francisco , Guerrero-Naranjo Jose-Luis , Martinez-Castellanos Maria A. 
Published: April 2021

AbstractBackgroundFibrin glue is an absorbable blood-derived product, a biological tissue adhesive which imitates the final stages of the coagulation cascade, it produces a firm clot, forming a seal along the whole length of the wound, the resultant fibrin clot degrades physiologically into granulation tissue 2 weeks after the application. Biological glue has been used extensively in many forms of surgical procedures. Its use in eye surgery has grown lately as we have evidence that showed it was effective in securing conjunctival grafts in pterygium surgery, in securing wounds after glaucoma surgery and more importantly in 20G and 23G vitrectomy.PurposeThe aim of this study is to present our experience in the use of fibrin glue in vitreoretinal surgery.Material and methodsWe included 281 eyes of 221 patients who underwent vitreoretinal surgery during the period of May 2009 to July 2012, the preoperative diagnoses were as following: proliferative diabetic retinopathy, rhegmatogenous retinal detachment, macular hole, epiretinal membrane, luxation of cataratous nucleous and cortex, intraocular lens luxation, penetrating trauma, silicone extraction, phaco + IOL + vitrectomy + Ahmed valve implant, vitreous biopsy and optic nerve pit associated to macular detachment. The procedures were performed with Alcon Accurus Surgical System 20-gauge, 23-gauge or a combination of both. We used fibrin glue in all of the 20-gauge sclerotomies and leaking 23-gauge sclerotomies, scleral wound for IOL extraction, conjunctival peritomy for buckle implantation, conjunctiva in Ahmed valve implant, corneal graft in corneal perforation in trauma and leaking corneal wounds for phacoemulsification, in an optic pit, and in subretinal space in a giant retinal tear.ResultsWe did not use any suture in any of the patients throughout the different procedures, there was no leakage in any wounds in the postoperative period, we found no inflammatory reaction, infection, and whenever we had excess amount, it was trimmed. Two patients presented a small dehiscence of the wound that was corrected in-office with a small amount of fibrin glue in the post-operative period.ConclusionsFibrin glue reduces surgical time, it is a good sealant, safe, with minimal allergic or toxic reactions and inflammation, minimizes bleeding, easy to undo and that eventually degrades. This small series shows that fibrin glue is a viable alternative for tissue coaptation in vitreoretinal surgery. However, further studies are required before fibrin glue takes the place of sutures.
Chitosan based antibacterial composite materials for leather industry: a review
Authors: Yuan Linlin , Yao Qingda , Liang Yongxian , Dan Ye , Wang Yixiao , Wen Huitao , Yang Yiqing , Dan Weihua 
Published: April 2021

Abstract
Chitosan is an amorphous translucent substance with a structural unit similar to the polysaccharide structure of the extracellular matrix, It has good antibacterial, biocompatible, and degradable properties. It has important application value in leather, water treatment, medicine, food and other fields, so chitosan and its modified products have received widespread attention. This article reviewed the preparation methods of chitosan-based antibacterial composites in recent years, including chitosan/collagen, chitosan/graphene, chitosan/tannic acid, and chitosan/polyethylene glycol composite materials, elaborates their modification methods and antibacterial mechanism were reviewed in detail, and its applications in the leather industry as antibacterial auxiliaries and water treatment antibacterial adsorption materials were discussed. Finally, the future development and challenges of chitosan-based composite materials in the leather industry were forecasted.

Graphical abstract
Validation of imaging reporting and data system of coronavirus disease 2019 lexicons CO-RADS and COVID-RADS with radiologists’ preference: a multicentric study
Authors: Atta Haisam , Hasan Hosam A. , Elmorshedy Reham , Gabr Adel , Abbas Wael A. , El-Barody Mohamed M. 
Published: April 2021

Abstract
Background
A retrospective multicentric study gathered 1439 CT chest studies with suspected coronavirus disease 2019 (COVID-19) affection. Three radiologists, blinded to other results, interpreted all studies using both lexicons with documentation of applicability and preferred score in assessing every case. The purpose of the study is to assess COVID-19 standardized assessment schemes’ (CO-RADS and COVID-RADS lexicons) applicability and diagnostic efficacy.

Results
This study included 991 RT-PCR-confirmed CT studies. An almost perfect agreement was found in COVID-RADS among the three observers (Fleiss Kappa = 0.82), opposed by a substantial agreement in CO-RADS (Κ = 0.78). The preference records favor COVID-RADS/CO-RADS in 78.5%/12.5%, 75.5%/24.5%, and 73.4%/24.5% regarding the three radiologists’ records, respectively. The distinguishability between positive and negative RT-PCR cases was 0.92 for COVID-RADS, while it was 0.85 for CO-RADS. On the other hand, both lexicons’ performance regarding clinical diagnosis and clinical suspicion index was 0.93 for COVID-RADS and 0.94 for CO-RADS. A very high to excellent agreement between the three observers for COVID-RADS/CO-RADS preference was concluded (Fleiss Kappa = 0.80 to 0.94). These results were statistically significant (p < 0.001).

Conclusion
Both lexicon scores (CO-RADS and COVID-RADS) were found to be applicable in the COVID-19 structured report with the preference of COVID-RADS in more than 50% of cases. The diagnostic accuracy of COVID-RADS against RT-PCR was higher than that of CO-RADS.
Is climate change a mental health crisis?
Authors: Romeu Daniel 
Published: April 2021

SummaryThe Earth's climate is in a complex state of change as a result of human activity. The interface between climate change and physical health has received significant attention, but its effects on mental health and illness are less understood. This article provides an insight into the psychiatric sequelae of climate change, suggests strategies that psychiatrists can use to take action, and argues that it is their responsibility to do so.
Cognitive remediation and professional insertion of people with schizophrenia: RemedRehab, a randomized controlled trial
Authors: Cervello S. , Dubreucq J. , Trichanh M. , Dubrulle A. , Amado I. , Bralet M. C. , Chirio-Espitalier M. , Delille S. , Fakra E. , Francq C. , Guillard-Bouhet N. , Graux J. , Lançon C. , Zakoian J. M. , Gauthier E. , Demily C. , Franck N. 
Published: April 2021

Abstract

Background
People suffering from schizophrenia cannot easily access employment in European countries. Different types of vocational programs coexist in France: supported employment, sheltered employment (ShE), and hybrid vocational programs. It is now acknowledged that the frequent cognitive impairments constitute a major obstacle to employment for people with schizophrenia. However, cognitive remediation (CR) is an evidence-based nonpharmacological treatment for these neurocognitive deficits.

Methods
RemedRehab was a multicentric randomized comparative open trial in parallel groups conducted in eight centers in France between 2013 and 2018. Participants were recruited into ShE firms before their insertion in employment (preparation phase). They were randomly assigned to cognitive training Cognitive Remediation for Schizophrenia (RECOS) or Treatment As Usual (TAU). The aim of the study was to compare with the benefits of the RECOS program on access to employment and work attendance for people with schizophrenia, measured by the ratio: number of hours worked on number of hours stipulated in the contract.

Results
Seventy-nine patients were included in the study between October 2018 and September 2019. Fifty-three patients completed the study. Hours worked / planned hours equal to 1 or greater than 1 were significantly higher in the RECOS group than in the TAU group.

Conclusions
Participants benefited from a RECOS individualized CR program allows a better rate of work attendance in ShE, compared to the ones benefited from TAU. Traditional vocational rehabilitation enhanced with individualized CR in a population of patients with schizophrenia is efficient on work attendance during the first months of work integration.
Consensus on Treatment and Follow-Up for Biochemical Recurrence in Castration-Sensitive Prostate Cancer: A Report From the First Global Prostate Cancer Consensus Conference for Developing Countries
Authors: Monteiro Fernando S. M. , Schutz Fabio A. , Morbeck Igor A. P. , Bastos Diogo A. , de Padua Fernando V. , Costa Leonardo A. G. A. , Maia Manuel C. , Rinck Jr Jose A. , Zequi Stenio de Cassio , da Trindade Karine M. , Alfer Jr Wladimir , Nahas William C. , dos Santos Lucas V. , Ferrigno Robson , da Rosa Diogo A. R. , Sade Juan P. , Orlandi Francisco J. , de Oliveira Fernando N. G. , Soares Andrey 
Published: April 2021

PURPOSE To present a summary of the treatment and follow-up recommendations for the biochemical recurrence in castration-sensitive prostate cancer (PCa) acquired through a questionnaire administered to 99 PCa experts from developing countries during the Prostate Cancer Consensus Conference for Developing Countries. METHODS A total of 27 questions were identified as related to this topic from more than 300 questions. The clinician's responses were tallied and presented in a percentage format. Topics included the use of imaging for staging biochemical recurrence, treatment recommendations for three different clinical scenarios, the field of radiation recommended, and follow-up. Each question had 5-7 relevant response options, including “abstain” and/or “unqualified to answer,” and investigated not only recommendations but also if a limitation in resources would change the recommendation. RESULTS For most questions, a clear majority (> 50%) of clinicians agreed on a recommended treatment for imaging, treatment scenarios, and follow-up, although only a few topics reached a consensus > 75%. Limited resources did affect several areas of treatment, although in many cases, they reinforced more stringent criteria for treatment such as prostate-specific antigen values > 0.2 ng/mL and STAMPEDE inclusion criteria as a basis for recommending treatment. CONCLUSION A majority of clinicians working in developing countries with limited resources use similar cutoff points and selection criteria to manage patients treated for biochemically recurrent castration-sensitive PCa.
“Waiving” Goodbye to PE: State Law and School Exemption and Substitution Practices in the United States
Authors: Chriqui Jamie F. , Leider Julien , Piekarz-Porter Elizabeth , Lin Wanting , Turner Lindsey , Michael Shannon L. , Brener Nancy , Perna Frank 
Published: April 2021

ABSTRACT

Purpose
The importance of schools providing physical education (PE) and promoting physical activity (PA) and the benefits of PA for children are well documented. However, a majority of students do not get the nationally recommended 60 min of daily PA. Many states grant waivers, substitutions, or exemptions from PE despite national recommendations. This study examined the association between state laws allowing for the use of PE substitutions and exemptions and school-level substitution and exemption practices.

Methods
School-level PE exemption and substitution data from the 2014 School Health Policies and Practices Study were linked to state law data from the National Wellness Policy Study and the National Cancer Institute’s 2013 Classification of Laws Associated with School Students. The analytic sample included 320 schools located in 42 states. Separate multivariable logistic regression models linked five types of school PE exemptions/substitutions to corresponding state laws, controlling for school characteristics.

Results
Overall, 24 of the 42 states had laws addressing PE waivers, exemptions, or substitutions. Schools had higher odds of allowing PE substitutions for school sports (adjusted odds ratio (AOR), 3.59; 95% confidence interval (CI), 1.33–9.68), other school activities (AOR, 8.52; 95% CI, 2.90–25.03), and community sports (AOR, 4.30; 95% CI, 1.43–12.96) and allowing exemptions for fitness test scores (AOR, 4.67; 95% CI, 1.49–14.62) or vocational training (AOR, 5.92; 95% CI, 1.04–33.68) if state law allowed it, compared with schools in states that did not allow such practices.

Conclusions
Given the connection between PA and beneficial outcomes for children, decision makers, school administrators, practitioners, advocates, and researchers should consider and further examine how PE waiver, exemption, and substitution policies and practices may affect students’ PA and related outcomes.
Managerial Learning from Analyst Feedback to Voluntary Capex Guidance, Investment Efficiency, and Firm Performance
Authors: Bae Jihun , Biddle Gary C. , Park Chul W. 
Published: April 2021

We test predictions that managers issuing voluntary capex guidance learn from analyst feedback and that this learning enhances investment efficiency and firm performance. Our findings are consistent with these predictions. First, we find that managers’ capex adjustments and capex guidance revisions relate positively with analyst feedback measured by differences between postguidance analyst capex forecasts and managerial capex guidance. Second, changes in investment efficiency relate positively with analyst feedback. Third, subsequent firm financial performance relates positively with the predicted values of both managers’ capex adjustments and capex guidance revisions. These findings extend prior evidence regarding sources of managerial learning and investment efficiency and help to explain the active issuance of voluntary guidance by managers in settings where, as for capex guidance, the potential for managerial learning from related share price effects is limited, as we also explain. This paper was accepted by Brian Bushee, accounting.
Necesidades y dificultades de los/las profesionales sanitarios/as de los servicios de prevención de riesgos laborales de Cataluña
Authors: Vargas Leguás Hernán , Porcel Pérez Eva , Cortès Franch Imma 
Published: April 2021

Objetivo: conocer las dificultades y necesidades del personal de medicina de los servicios de prevención de riesgos laborales de Cataluña para desarrollar sus funciones sanitarias descritas por la ley.
Métodos: estudio Delphi en tres rondas. La selección de participantes se realizó diferenciadamente para servicios de prevención propios y ajenos. La primera ronda incluyó dos preguntas abiertas: ¿Qué dificultades tiene para realizar las funciones sanitarias de su SPRL? y ¿Qué necesidades tiene para realizar las funciones sanitarias de su SPRL? En la segunda y tercera ronda las personas participantes puntuaron las categorías identificadas en la primera ronda según su importancia y relevancia. Se calcularon un índice de acuerdo interjueces (ICC) y un “índice de preocupación (IP)”.
Resultados: la gestión de las personas trabajadoras con limitaciones y la vigilancia colectiva de la salud de baja calidad son las dificultades más importantes para los Servicios de Prevención Propios. Para los Ajenos, la falta de comunicación con otros organismos, la preeminencia de los criterios económicos y de rentabilidad asociado al alto volumen de trabajo son las más relevantes. La necesidad de establecer canales de comunicación con otras instituciones u organismos como la Atención Primaria, las Mutuas, el Instituto de Evaluaciones Médicas y las Unidades de Salud Laboral es común a ambos grupos.
Conclusiones: la diferente naturaleza de las actividades preventivas que realizan los servicios de prevención determina diferencias importantes en las dificultades expresadas, no así en las necesidades identificadas donde se encuentran puntos en común.
Análisis del ajuste de mascarillas autofiltrantes en combinación con las mascarillas quirúrgicas para la protección del profesional sanitario en su atención a pacientes afectos de SARS-COV-2 a partir de un estudio experimental
Authors: García Vela Raquel , Cabanas Valdés Rosa , Huertas Ríos Santos , Donat Roca Rafel , Monné Cuevas Pol , Moizé Arcone Luciana , Calvo Sanz Jordi 
Published: April 2021

Introducción: Un componente importante del equipo de protección individual (EPI) frente al SARS-CoV-2 son las mascarillas quirúrgicas y las mascarillas autofiltrantes (FFP). La norma europea EN 149 establece y clasifica las mascarillas autofiltrantes en tres niveles de protección dependiendo del porcentaje de fuga del total de partículas en suspensión del aire exterior hacia el aire interior FFP1, FFP2, FFP3. El objetivo de este e ensayo de laboratorio es determinar y cuantificar el nivel de ajuste de las mascarillas autofiltrantes FFP2 combinadas con las mascarillas quirúrgicas mediante series de pruebas de ajuste (fit test).
Material y Métodos: Se utilizó el equipo medidor de ajuste de mascarillas FFP modelo PortaCount® Pro + 8038 compatible con las normas y metodología de la OSHA (Occupational Safety and Health Administration) de los EEUU. Se realizaron series de pruebas de ajuste sobre diferentes modelos de mascarillas autofiltrantes FFP2 con y sin mascarilla quirúrgica para diferentes situaciones de respiración del trabajador participante en este experimento.
Resultados: El uso de la mascarilla quirúrgica sobre una mascarilla autofiltrante FFP2 aporta una mejora en la protección respiratoria determinante, incrementando el factor de ajuste hasta de +200 (el factor de ajuste mínimo debe ser 100).
Conclusiones: Las mascarillas quirúrgicas cuando se usan conjuntamente con las mascarillas autofiltrantes, podrían mejorar significativamente el grado de ajuste de todas las mascarillas autofiltrantes proporcionando una mayor eficacia de filtración y una mayor protección al usuario frente a la exposición a aerosoles.
Antimicrobial stewardship strategies in wound care: evidence to support the use of dialkylcarbamoyl chloride (DACC)- coated wound dressings
Authors: Rippon Mark G , Rogers Alan A , Ousey Karen 
Published: April 2021

Background:Traditionally, infections are treated with antimicrobials (for example, antibiotics, antiseptics, etc), but antimicrobial resistance (AMR) has become one of the most serious health threats of the 21st century (before the emergence of COVID-19). Wounds can be a source of infection by allowing unconstrained entry of microorganisms into the body, including antimicrobial-resistant bacteria. The development of new antimicrobials (particularly antibiotics) is not keeping pace with the evolution of resistant microorganisms and novel ways of addressing this problem are urgently required. One such initiative has been the development of antimicrobial stewardship (AMS) programmes, which educate healthcare workers, and control the prescribing and targeting of antimicrobials to reduce the likelihood of AMR. Of great importance has been the European Wound Management Association (EWMA) in supporting AMS by providing practical recommendations for optimising antimicrobial therapy for the treatment of wound infection. The use of wound dressings that use a physical sequestration and retention approach rather than antimicrobial agents to reduce bacterial burden offers a novel approach that supports AMS. Bacterial-binding by dressings and their physical removal, rather than active killing, minimises their damage and hence prevents the release of damaging endotoxins.Aim:Our objective is to highlight AMS for the promotion of the judicious use of antimicrobials and to investigate how dialkylcarbamoyl chloride (DACC)-coated dressings can support AMS goals.Method:MEDLINE, Cochrane Database of Systematic Reviews, and Google Scholar were searched to identify published articles describing data relating to AMS, and the use of a variety of wound dressings in the prevention and/or treatment of wound infections. The evidence supporting alternative wound dressings that can reduce bioburden and prevent and/or treat wound infection in a manner that does not kill or damage the microorganisms (for example, by actively binding and removing intact microorganisms from wounds) were then narratively reviewed.Results:The evidence reviewed here demonstrates that using bacterial-binding wound dressings that act in a physical manner (for example, DACC-coated dressings) as an alternative approach to preventing and/or treating infection in both acute and hard-to-heal wounds does not exacerbate AMR and supports AMS.Conclusion:Some wound dressings work via a mechanism that promotes the binding and physical uptake, sequestration and removal of intact microorganisms from the wound bed (for example, a wound dressing that uses DACC technology to successfully prevent/reduce infection). They provide a valuable tool that aligns with the requirements of AMS (for example, reducing the use of antimicrobials in wound treatment regimens) by effectively reducing wound bioburden without inducing/selecting for resistant bacteria.
Embankment Breach Research: Observed Internal Erosion Processes
Authors: Ali Abdelfatah K. , Hunt Sherry L. , Tejral Ronald D. 
Published: April 2021

HighlightsThis study provides data from internal erosion tests on four intermediate-scale homogeneous embankment dams.Soil properties influence the breach formation process and breach timing.Results showed that observed erosion rates of the internal flow path varied by several orders of magnitude.Quality control of embankment construction can greatly influence breach development.Abstract. Internal erosion and embankment overtopping are the two most common causes of embankment dam and levee failures and incidents. Internal erosion is the removal of soil material by the flow of water through a continuous defect, cavity, or crack within a compacted fill and/or its foundation. Internal erosion initiates from vulnerabilities within the embankment. The embankment soil material plays a key role in both the erosion process and rate of failure, but characterizing soil properties and how they relate to the rate of failure can be challenging. Soil properties such as texture, density, strength, moisture content, and erodibility can vary greatly; thus, it is important to study the effects of these properties on the breach formation process and breach timing. The USDA Agricultural Research Service performed internal erosion breach experiments on four intermediate-scale homogeneous earthen embankments constructed of soils ranging from a silty sand to a lean clay material. The embankments were constructed to a height of 1.3 m, a top width of 1.8 m, and upstream and downstream slopes of 3(H):1(V). The embankment materials were characterized by water content, density, texture, strength, and erodibility. Erodibility was measured using a jet erosion test (JET) apparatus. A 40 mm diameter, continuous steel pipe was placed through each embankment during construction and removed to form an open-ended void through the embankment connected to the upstream reservoir. The removal of the pipe initiated internal erosion. The objectives of the experiments were to observe the development of the internal erosion process over time and to examine the influence of soil properties on the erosion rate, breach timing, geometry of the breach opening, and breach outflow. The rate of erosion and failure observed in these tests varied by several orders of magnitude, with the silty sand embankment eroding most rapidly and the lean clay embankment with a mean moisture content of 18% dry basis at standard compaction eroding the slowest. These observations were indicative of the soil textures. Although the two lean clay embankments were constructed of similar soils, the difference in erosion rates speak to the importance of quality control (e.g., compaction moisture content) during construction. Soil properties including soil texture, erodibility, and compaction moisture content are key predictors of erosion rate and observed failure. Keywords: Breach, Dam failure, Dams, Embankments, Erodibility, Internal erosion, Levees, Overtopping.