bluuebunny/crossref_metadata_2025_split huggingface dataset:
RETRACTED ARTICLE: Human motion capture system in sports performance based on Internet of Things technology and wireless inertial sensor
Authors: Xu Wenfeng 
Published: October 2021

AbstractTaking human movements has very good prospects of application in sports, animated projects, medicine and health and other areas. This article aims to study the human motion capture system in sports performances based on the Internet of Things technology and wireless inertial sensors. This article first introduces the theory and characteristics of the Internet of Things and motion capture; next, according to the different characteristics of the sensors in the inertial motion capture system, a two-step Kalman filter is proposed to process the accelerometer and the magnetometer separately and, finally, the structure of this article. The human body motion model is used to analyze the acceleration dynamic error that occurs during the motion. In addition, an inertial motion capture system is constructed to obtain and visualize the structure of each motion node. The experimental results in this paper show that the Kalman filtering algorithm can ensure the accuracy of angle estimation under different motion states and has good fault tolerance to external interference. Among them, the error of the static state is reduced by 23.1%.
Task allocation and route planning of multiple UAVs in a marine environment based on an improved particle swarm optimization algorithm
Authors: Yan Ming , Yuan Huimin , Xu Jie , Yu Ying , Jin Libiao 
Published: October 2021

AbstractUnmanned aerial vehicles (UAVs) are considered a promising example of an automatic emergency task in a dynamic marine environment. However, the maritime communication performance between UAVs and offshore platforms has become a severe challenge. Due to the complex marine environment, the task allocation and route planning efficiency of multiple UAVs in an intelligent ocean are not satisfactory. To address these challenges, this paper proposes an intelligent marine task allocation and route planning scheme for multiple UAVs based on improved particle swarm optimization combined with a genetic algorithm (GA-PSO). Based on the simulation of an intelligent marine control system, the traditional particle swarm optimization (PSO) algorithm is improved by introducing partial matching crossover and secondary transposition mutation. The improved GA-PSO is used to solve the random task allocation problem of multiple UAVs and the two-dimensional route planning of a single UAV. The simulation results show that compared with the traditional scheme, the proposed scheme can significantly improve the task allocation efficiency, and the navigation path planned by the proposed scheme is also optimal.
Scoping reviews: reinforcing and advancing the methodology and application
Authors: Peters Micah D. J. , Marnie Casey , Colquhoun Heather , Garritty Chantelle M. , Hempel Susanne , Horsley Tanya , Langlois Etienne V. , Lillie Erin , O’Brien Kelly K. , Tunçalp Ӧzge , Wilson Michael G. , Zarin Wasifa , Tricco Andrea C. 
Published: October 2021

AbstractScoping reviews are an increasingly common approach to evidence synthesis with a growing suite of methodological guidance and resources to assist review authors with their planning, conduct and reporting. The latest guidance for scoping reviews includes the JBI methodology and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses—Extension for Scoping Reviews. This paper provides readers with a brief update regarding ongoing work to enhance and improve the conduct and reporting of scoping reviews as well as information regarding the future steps in scoping review methods development. The purpose of this paper is to provide readers with a concise source of information regarding the difference between scoping reviews and other review types, the reasons for undertaking scoping reviews, and an update on methodological guidance for the conduct and reporting of scoping reviews.Despite available guidance, some publications use the term ‘scoping review’ without clear consideration of available reporting and methodological tools. Selection of the most appropriate review type for the stated research objectives or questions, standardised use of methodological approaches and terminology in scoping reviews, clarity and consistency of reporting and ensuring that the reporting and presentation of the results clearly addresses the review’s objective(s) and question(s) are critical components for improving the rigour of scoping reviews.Rigourous, high-quality scoping reviews should clearly follow up to date methodological guidance and reporting criteria. Stakeholder engagement is one area where further work could occur to enhance integration of consultation with the results of evidence syntheses and to support effective knowledge translation. Scoping review methodology is evolving as a policy and decision-making tool. Ensuring the integrity of scoping reviews by adherence to up-to-date reporting standards is integral to supporting well-informed decision-making.
Increasing retractions of meta-analyses publications for methodological flaw
Authors: Chen Chia-Yun , Kang Yi-No , Kuo Ken N. , Glasziou Paul , Chen Kee-Hsin 
Published: October 2021

AbstractPurpose of this letter was to explore the trends regarding methodological flaws of systematic review and meta-analyses (SRMAs) based on retraction notes in the past decades, and the categories of reasons for the retractions. Content analysis with descriptive statistics, Cochran Q test, and multinomial logistic regression were used. Based on 187 records of retracted SRMAs, retraction announcements can be categorized into academic ethical violation, methodological flaw, and writing or reporting problem. The numbers of academic ethical violation were significantly higher than those with methodological flaw (z = 3.51; p < 0.01) or writing problem (z = 8.58; p < 0.001). The numbers of methodological flaw were also higher than that with writing problem (z = 6.47; p < 0.001). Moreover, an increased proportion of methodological flaw was observed since 2006, and the retraction year was significantly associated with increased proportion of methodological flaw when academic ethical violation as the reference group.
Theoretical approaches to process evaluations of complex interventions in health care: a systematic scoping review protocol
Authors: Quasdorf Tina , Clack Lauren , Laporte Uribe Franziska , Holle Daniela , Berwig Martin , Purwins Daniel , Schultes Marie-Therese , Roes Martina 
Published: October 2021

Abstract
Background
Complex interventions in health care are characterized by multiple interacting components as well as by numerous nonlinear interactions with the social systems within which they are being implemented. The process of developing, evaluating and implementing complex interventions is therefore challenging. Established guidance such as the MRC (Medical Research Council) framework for developing and evaluating complex interventions refers to process evaluations as an integral part of the development of complex evidence-based interventions. Even though the need for process evaluations is recognized, the realization of such approaches is challenging because methodological instruction is sparse, and the phenomenon of interest is complex. A number of theoretical approaches indicating how to conduct process evaluations of complex interventions in health care exist, but a systematic and comprehensive overview of these is missing. Thus, the objective of the systematic scoping review described herein is to provide an overview and analysis of theoretical approaches suitable for the planning and conducting of process evaluations.

Methods
The design and conduct of this review will follow the procedures of a systematic scoping review. The search strategy will be developed following the BeHEMoTh (Behaviour of interest; Health context; Exclusions; Models or Theories) template which has been conceptualized for structured reviews of theory. The systematic search of the MEDLINE (via PubMed), CINAHL (via EBSCO) and PsycInfo (via EBSCO) electronic databases will be complemented by “hand searching” techniques. Study selection, data extraction, and data analysis will be performed by tandems of two researchers independently of each other. Divergent decisions and judgements between the two researchers will be discussed by the whole review team.

Discussion
The findings from this scoping review will provide an overview and comparison of theoretical approaches suitable for process evaluations of complex interventions in health care. The review results will support researchers in choosing the theoretical approach that best fits the respective focus of their process evaluation study.

Systematic review registration
This study has been registered with PROSPERO (International Prospective Register of Systematic Reviews) under registration number CRD42020211732.
National Nutrition Communication Campaign in Indonesia: a cross-sectional study of factors associated with exposure
Authors: Hunt Leiema , Norton Abigail , Daines Chantel , Friedbaum Evie , Topham Danica , Moffat Ryan , Torres Scott , Linehan Mary , Jusril Hafiza , Hall Cougar , Crookston Benjamin , West Josh 
Published: October 2021

Abstract
Background
Reducing childhood stunting continues to be a priority in Indonesia. In 2015, the National Nutrition Communication Campaign (NNCC) implemented mass media and interpersonal communication (IPC) interventions to disseminate stunting-related information. Whereas other studies of the NNCC’s impact on attitudes and behaviors are currently underway, the purpose of this study was to better understand the factors associated with exposure to the media and IPC components of the NNCC.

Methods
A cross-sectional survey was conducted following the NNCC media and IPC campaigns in rural Indonesia. The final study sample included 1734 mothers. Survey data was collected from each participant by trained interviewers using an electronic tablet. Responses relating to demographic and socioeconomic factors, use of social media and WhatsApp, and electronic device ownership were analyzed. Logistic regression analyses, using SAS version 9.4, were conducted to evaluate the relationship between technology-related items and exposure to both the media and the IPC interventions.

Results
Owning an internet device (OR = 1.643, CI = 1.237–2.183, p < 0.001), accessing social media (OR = 1.81, CI = 1.32–2.49, p < 0.001), using a device to access health information (OR = 2.068, CI = 1.469–2.911, p < 0.0001), and accessing WhatsApp (OR = 1.663, CI = 1.175–2.355, p < 0.05) were positively related to exposure to NNCC messages meant to change behavior to decrease stunting. In separate analyses, owning an internet device (OR = 0.609, CI = 0.459–0.81, p < 0.001) accessing social media (OR = 0.626, CI = 0.459–0.854, p < 0.05), using a device to access health information (OR = 0.528, CI = 0.377–0.740, p < 0.001), and accessing WhatsApp (OR = 0.688, CI = 0.489–0.968, p < 0.05) were negatively related to IPC exposure. Mothers with access to internet-accessible devices were more likely to be exposed to the media campaign component to decrease stunting while mothers without access to internet-accessible devices were more likely to be exposed through IPC.

Conclusions
Mothers who owned devices that could access the internet were more likely to have been exposed to the media campaign component to decrease stunting by behavior change but were less likely to participate in IPC activities. The opposite was true for mothers who did not have access to internet-accessible devices. These findings may be used to inform future community health efforts in rural Indonesia and similar regions that may be considering the use of both mass media and interpersonal interventions to influence health behaviors in order to decrease stunting.
Breast cancer growth and proliferation is suppressed by the mitochondrial targeted furazano[3,4-b]pyrazine BAM15
Authors: Zunica Elizabeth R. M. , Axelrod Christopher L. , Cho Eunhan , Spielmann Guillaume , Davuluri Gangarao , Alexopoulos Stephanie J. , Beretta Martina , Hoehn Kyle L. , Dantas Wagner S. , Stadler Krisztian , King William T. , Pergola Kathryn , Irving Brian A. , Langohr Ingeborg M. , Yang Shengping , Hoppel Charles L. , Gilmore L. Anne , Kirwan John P. 
Published: October 2021

Abstract
Background
Enhanced metabolic plasticity and diversification of energy production is a hallmark of highly proliferative breast cancers. This contributes to poor pharmacotherapy efficacy, recurrence, and metastases. We have previously identified a mitochondrial-targeted furazano[3,4-b]pyrazine named BAM15 that selectively reduces bioenergetic coupling efficiency and is orally available. Here, we evaluated the antineoplastic properties of uncoupling oxidative phosphorylation from ATP production in breast cancer using BAM15.

Methods
The anticancer effects of BAM15 were evaluated in human triple-negative MDA-MB-231 and murine luminal B, ERα-negative EO771 cells as well as in an orthotopic allograft model of highly proliferative mammary cancer in mice fed a standard or high fat diet (HFD). Untargeted transcriptomic profiling of MDA-MB-231 cells was conducted after 16-h exposure to BAM15. Additionally, oxidative phosphorylation and electron transfer capacity was determined in permeabilized cells and excised tumor homogenates after treatment with BAM15.

Results
BAM15 increased proton leak and over time, diminished cell proliferation, migration, and ATP production in both MDA-MB-231 and EO771 cells. Additionally, BAM15 decreased mitochondrial membrane potential, while inducing apoptosis and reactive oxygen species accumulation in MDA-MB-231 and EO771 cells. Untargeted transcriptomic profiling of MDA-MB-231 cells further revealed inhibition of signatures associated with cell survival and energy production by BAM15. In lean mice, BAM15 lowered body weight independent of food intake and slowed tumor progression compared to vehicle-treated controls. In HFD mice, BAM15 reduced tumor growth relative to vehicle and calorie-restricted weight-matched controls mediated in part by impaired cell proliferation, mitochondrial respiratory function, and ATP production. LC-MS/MS profiling of plasma and tissues from BAM15-treated animals revealed distribution of BAM15 in adipose, liver, and tumor tissue with low abundance in skeletal muscle.

Conclusions
Collectively, these data indicate that mitochondrial uncoupling may be an effective strategy to limit proliferation of aggressive forms of breast cancer. More broadly, these findings highlight the metabolic vulnerabilities of highly proliferative breast cancers which may be leveraged in overcoming poor responsiveness to existing therapies.
Clinical predictors of severe dengue: a systematic review and meta-analysis
Authors: Tsheten Tsheten , Clements Archie C. A. , Gray Darren J. , Adhikary Ripon K. , Furuya-Kanamori Luis , Wangdi Kinley 
Published: October 2021

Abstract
Background
Severe dengue is a life-threatening complication; rapid identification of these cases, followed by adequate management is crucial to improve the clinical prognosis. Therefore, this study aimed to identify risk factors and predictors of severe dengue.

Methods
A literature search for studies reporting risk factors of severe dengue among individuals with dengue virus infection was conducted in PubMed, Scopus and Web of Science database from inception to December 31, 2020. Pooled odds ratios (ORs) for patients’ demographic characteristics, co-morbidities, and warning signs were estimated using an inverse variance heterogeneity model.

Results
We included 143 articles in the meta-analysis from a total of 13 090 articles retrieved from the literature search. The risk factors of severe dengue were: being a child [OR = 1.96; 95% confidence interval (CI): 1.22–3.13], secondary infection (OR = 3.23; 95% CI: 2.28–4.57), and patients with pre-existing diabetes (OR = 2.88; 95% CI: 1.72–4.81) and renal disease (OR = 4.54; 95% CI: 1.55–13.31). Warning signs strongly associated with severe disease were increased haematocrit with a concurrent decrease in platelet count (OR = 5.13; 95% CI: 1.61–16.34), abdominal pain (OR = 2.00; 95% CI: 1.49–2.68), lethargy (OR = 2.73; 95% CI: 1.05–7.10), vomiting (OR = 1.80; 95% CI: 1.43–2.26), hepatomegaly (OR = 5.92; 95% CI: 3.29–10.66), ascites (OR = 6.30; 95% CI: 3.75–10.60), pleural effusion (OR = 5.72; 95% CI: 3.24–10.10) and melena (OR = 4.05; 95% CI: 1.64–10.00).

Conclusions
Our meta-analysis identified children, secondary infection, diabetes and renal disease(s) as important predictors of severe dengue. Our finding also supports the predictive ability of the WHO warning signs to identify severe dengue. These findings are useful for clinicians to identify severe dengue for management and timely interventions.
Learning self-care skills after spinal cord injury: a qualitative study
Authors: van Diemen Tijn , van Nes Ilse J. W. , van Laake-Geelen Charlotte C. M. , Spijkerman Dorine ,   SELF-SCI Group, Geertzen Jan H. B. , Post Marcel W. M. 
Published: October 2021

Abstract
Background
People with a recent spinal cord injury (SCI) often follow intensive rehabilitation. Learning appropriate self-care, deal with their impairments and prevent secondary health conditions (SHCs), is highly important during rehabilitation. To date it is not clear how self-care skills are taught to people with SCI. The objective of this study was to understand how people with SCI experienced the learning of appropriate self-care skills during inpatient rehabilitation, including the role of the rehabilitation team.

Methods
Individual semi-structured interviews were conducted with 15 people with SCI, recently discharged from initial inpatient rehabilitation. Interviews were audio-taped, transcribed and analyzed thematically.

Results
Two main themes and seven sub-themes were identified. Participants stated that the contribution of the rehabilitation team to learning self-care, including prevention of SHCs, was mostly made by optimizing opportunities to learn through experience. For preventing SHCs, education and lessons learned from the professionals during therapy and the formal educational program, was experienced as especially important. Further, the motivational attitude of the professionals which participants found stimulating and was based on respect, combined with their positive contribution as one team, were seen as essentials elements for learning appropriate self-care. However participants did not recognize the contribution of the nursing staff as part of their rehabilitation, although it was seen as very important. An important aspect of the participants’ own contribution was challenging oneself to learn self-care. This was done in different ways by the participants. Further, their own mental adjustment was considered important in the learning process. The gaining of confidence was by most participants seen as personal characteristic, although they also recognized the importance of the team effort and the experiences they underwent.

Conclusions
Learning appropriate self-care was mostly done through experience, by challenging themselves, and making use of the opportunities given by the members of the rehabilitation team. The same strategies used by the rehabilitation team to teach people with SCI to perform appropriate self-care, were also helpful for the participants to gain confidence. Explicit attention for self-care training as an important goal in SCI rehabilitation may strengthen the nursing staff’s role and stimulate interdisciplinary working.
Next frontier in tumor immunotherapy: macrophage-mediated immune evasion
Authors: Qiu Yingqi , Chen Tong , Hu Rong , Zhu Ruiyi , Li Chujun , Ruan Yingchen , Xie Xiaoling , Li Yuhua 
Published: October 2021

AbstractTumor-associated macrophages (TAMs), at the core of immunosuppressive cells and cytokines networks, play a crucial role in tumor immune evasion. Increasing evidences suggest that potential mechanisms of macrophage-mediated tumor immune escape imply interpretation and breakthrough to bottleneck of current tumor immunotherapy. Therefore, it is pivotal to understand the interactions between macrophages and other immune cells and factors for enhancing existing anti-cancer treatments. In this review, we focus on the specific signaling pathways through which TAMs involve in tumor antigen recognition disorders, recruitment and function of immunosuppressive cells, secretion of immunosuppressive cytokines, crosstalk with immune checkpoints and formation of immune privileged sites. Furthermore, we summarize correlative pre-clinical and clinical studies to provide new ideas for immunotherapy. From our perspective, macrophage-targeted therapy is expected to be the next frontier of cancer immunotherapy.
Multifaced roles of PLAC8 in cancer
Authors: Mao Misha , Cheng Yifan , Yang Jingjing , Chen Yongxia , Xu Ling , Zhang Xun , Li Zhaoqing , Chen Cong , Ju Siwei , Zhou Jichun , Wang Linbo 
Published: October 2021

AbstractThe role of PLAC8 in tumorigenesis has been gradually elucidated with the development of research. Although there are common molecular mechanisms that enforce cell growth, the impact of PLAC8 is varied and can, in some instances, have opposite effects on tumorigenesis. To systematically understand the role of PLAC8 in tumors, the molecular functions of PLAC8 in cancer will be discussed by focusing on how PLAC8 impacts tumorigenesis when it arises within tumor cells and how these roles can change in different stages of cancer progression with the ultimate goal of suppressing PLAC8-relevant cancer behavior and related pathologies. In addition, we highlight the diversity of PLAC8 in different tumors and its functional output beyond cancer cell growth. The comprehension of PLAC8’s molecular function might provide new target and lead to the development of novel anticancer therapies.
A retrospective towards a biodegradable material concept for future Indonesian sustainable architecture
Authors: Lianto Fermanto , Husin Denny , Thedyardi Clinton , Choandi Mieke , Trisno Rudy 
Published: October 2021

AbstractThe awareness of the negative effect of the intensive usage of synthetic material has led to a significant phenomenon in recent global development. Moving forward to become a fully ready developed country, Indonesia shall move toward a more sustainable architecture for presenting a greener environment. Despite blessed with a distinctive collection of tropical material variants, reflected in its vernacular architecture, advanced material development must be invented to promote more progressive architecture in Indonesia. This research illustrates a new perspective regarding biodegradable material concepts for future Indonesian sustainable architecture. It is produced by respecting local and global development trends by using a bibliographic coupling and experimental methods in the laboratory to contribute to Indonesian sustainable architecture. A retrospective is aimed to highlight Indonesian biodegradable material and Indonesian vernacular architecture potency; it is presented as follows; (1) Understanding local–global trends in biodegradable architecture; (2) Indonesian potency on biodegradable materials; (3) A biodegradable material concept as an alternative perspective for Indonesian sustainable architecture. As a result, a new concept is proposed as an alternative for developing Indonesian biodegradable building materials. A more profound sustainable architecture is expected to engage local craftsmanship while highlighting unique biodegradable materials easily found in the surrounding environment, such as Indonesian Kombucha Tea and Indonesian Coffee.