bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Perception of Using Technology Canva Application as a Media for English Teacher Creating Media Virtual Teaching and English Learning in Loei Thailand
Authors: Elsa Elsa , Anwar Khoirul 
Published: June 2021

Online Learning requires teachers to think creatively and innovatively to attract students. Learning media becomes the main factor in helping teachers make it happen. This study aims to find out the perception of English teachers in the use of canva application as a virtual learning media creation in Loei Thailand.This research applies mixed method design that starts with collecting quantitative data. After analyzing quantitative data, qualitative data is then collected and analyzed. 20 teachers were asked to fill out a questionnaire to find out their perspective on the use of Canva.
This research has proven that canva application can be used to create learning media. The result in this research was the function and benefit of canva divided into two, namely as sumplemen and subtitusi. The supplement function of canva is (1) Canva fasilitated teacher to make learning media, (2) Canva Application Improve online teaching process. The substitution function of canva is (1) Canva Application Improves learning media effectively, (2) Learning media of Canva is easy to distribute to students (3) Canva application can help the technology requirement. That is, the function of Canva obtained in this study.
Physicochemical and antibacterial activities of Apis honey types derived from Coorg, Karnataka, India
Authors: M Bhushanam , S Madhusudhan , Bajpai Monika , G Sibi 
Published: June 2021

Natural honey has various ingredients in it that contribute to its incredible properties. The aim of this investigation was to evaluate the physicochemical and antibacterial activity of various Apis honey from Coorg, Karnataka. Four samples of Apis honey viz., A. florea, A. mellifera, A. cerana and A. dorsata were collected from various regions of Coorg, Karnataka. The honey samples' physicochemical properties and antibacterial activities against Streptococcus sp., Staphylococcus aureus, Bacillus subtilis and Enterococcus sp were determined in vitro. The moisture and ash content varied from 13.6 - 17.2% and 0.32 – 0.49%, respectively. Hydroxy methyl furfurals) content of A. dorsata honey samples was highest with 9.2±0.5 mg/Kg and least was recorded with 6.8±0.4 mg/Kg for A. florae honey. The reducing sugar content of A. florea honey sample was highest with 87.5±3.2 (%) and the peroxide levels were in the range of 10.2 – 14.9 µg/g/h at 20°C. The antibacterial assay revealed that S. aureus, Enterococcus sp and Streptococcus sp were most susceptible against the honey varieties tested and minimum inhibitory concentration (MIC) values between 25-6.5 (%v/v) were determined. In conclusion, honey varieties from Coorg could be used in specific antibacterial prophylaxis as the activity depends on the honey bee species, their metabolism and floral sources in specific geographical regions.
Pengaruh Penerimaan Teknologi dengan Kebergunaan Web:
Authors: Chabibie M. Hasan , Hakim Wildan 
Published: June 2021

Penggunaan internet di Indonesia telah memungkinkan proses belajar berlangsung secara daring. Melalui sebuah portal khusus yang beralamatkan di http://belajar.kemdikbud.go.id pengguna internet dari berbagai kalangan terhubung langsung dengan beragam content (materi) pembelajaran yang tersedia. Portal rumah belajar merupakan media belajar berbasis internet (online) yang dibangun secara khusus untuk memudahkan guru dan siswa mendapatkan bahan atau materi untuk kepentingan mengajar siswa. Berbeda dengan situs internet pada umumnya, portal rumah belajar ini lebih menekankan sisi interaktivitas antara pengguna, yakni guru dan siswa, dengan portal rumah belajar itu sendiri. Lewat portal rumah belajar, para guru dan siswa bisa mengakses bahan belajar, melakukan simulasi interaktif serta berkomunikasi dan berinteraksi antarkomunitas pendidikan. Penelitian ini bertujuan mencari Pengaruh Penerimaan Teknologi dengan Kebergunaan Web di Portal Rumah Belajar dengan sasaran para guru dan siswa selaku praktisi akademis dan penyampai pesan pembelajaran di sekolah. Hasil penelitian menunjukkan, penerimaan pengguna terhadap terknologi internet sebagai sarana pembelajaran berkaitan erat dengan tujuan dan sikap responden saat mengakses Portal Rumah Belajar. Tingkat kebergunaan Portal Rumah Belajar yang dirasakan pengguna, berkorelasi erat dengan satisfaction, download delay, dan content yang disajikan.
Keywords: Penerimaan informasi, penerimaan teknologi, web usability, kepuasan penggunaan portal Rumah Belajar
Cells at Work: Media Integration Mapping
Authors: Cintya Hedi Amelia Bella , Mansoor Alvanov Zpalanzani , Ahmad Hafiz Aziz 
Published: June 2021

Cells at Work is a Japanese comic by Shimizu Akane that tells about body cells’ science. The comic gains popularity as edutainment and adapted into several educative media such as spin-offs comics, picture books, games, stage plays, and many more. While it can act as good alternatives to learn about the science of cells, adaptation to media that is too diverse can create ambiguity, confusing its users. The purpose of this research is to create a media integration mapping of Cells at Work. This research employs a qualitative descriptive method. The descriptive method is used to describe and determine the use of each adaptation medium. Then this research will map the media integration. The findings show that the diversity of educational media has its roles and purposes. Spin-off comics have specific topics that can broaden the user's knowledge of various cells. At the same time, picture books are aimed at readers who want to study cells in depth without any side stories. Games are aimed at people who prefer interactive learning. The findings from this study can be used as a consideration for creating and integrating educational media.
Keywords: media integration; mapping; educational comic; science; cells at work.
Kajian Gamifikasi Mekanik sebagai Variabel dalam Literasi Media Board Game
Authors: Amalia Fadhilah , Mansoor Alvanov Zpalanzani 
Published: June 2021

In accordance with the changes that occur in 21st century, the world’s media industry also undergoes rapid changes. The variety of media that continues to emerge and develop in all levels of society has a significant impact, one of which is the board game media. This phenomenon has attracted the attention of researchers to examine board game media as a media education towards media literacy skills. Media literacy is the ability to seek, find, and use information from media messages by adapting cognitive abilities and critical thinking in analyzing and questioning media messages that are seen, read, and watched. Media literacy has a broad scope that is believed to be able to function as the stronghold for the public in ability to think critically. This study was conducted to examine the gamification mechanics element as an independent variable in the board game media literacy, focusing on the concept of media literacy based on individual competence, especially on critical understanding criteria.
Keywords: board game; critical understanding; gamification mechanics; media literacy.
The enzyme activity dynamic relationship with the content of structural polypeptides of enterocyte membranes in cattle fetal
Authors: Masiuk D. M. 
Published: June 2021

The article performs new data on the relationship between the hydrolytic and transport enzyme activity at different poles of the enterocytes plasmolemma of cow's fetal large intestine with the content of individual fractions of polypeptides. An expressive direct dependence of enzyme activity dynamics on the apical and basolateral membranes of enterocytes containing low molecular weight proteins and an inverse relationship with the concentration of proteins with medium and large molecular weights has been proved. It was found that the alkaline activity of the phosphatase and γ-glutamyltransferase on the apical domain of enterocyte plasmolemma is directly related to the proteins content with molecular masses of 9.6–14.2 kD, 21 kD, 22.5 kD, 26 kD, 33 kD, 35 kD, 170–185 kD, and 205 kD (P ≤ 0.05–0.001). Gamma-glutamyltransferase activity is straightly related to protein quantity with molecular weights of 15.5 kDa and 39 kD (P ≤ 0.05). In contrast, alkaline phosphatase and GGT activity have inverse correlations with the content of polypeptides with molecular masses of 46 kD, 63 kD, and 250 kD in the apical membrane of enterocytes (P ≤ 0.01–0.001). The lactase activity in the cattle enterocytes apical membrane during the test period has significant direct correlations only with the amount of the polypeptide of polypeptides with molecular weights of 31 kD, 39 kD, and 100 kD (P ≤ 0.05–0.01) and inverse relationships containing proteins with molecular masses of 46 kD and 120 kD (P ≤ 0.05). A linear dependence of the different ATPase activity of the apical membrane of red blood cells containing proteins with molecular weights of 9.6–14.2 kD, 15.5 kD, 21 kD, 22.5 kD, 33 kD, 35 kD, 39 kD, and 205 kD (P ≤ 0.05–0.001) was observed. Alkaline phosphatase activity in the apical membrane of enterocytes is only directly related to the number of proteins with molecular weights of 17 kD and 24 kD (P ≤ 0.001) in this domain. It inversely depends on the content of proteins with molecular masses of 9.6–14.2 kD and 52 kD (P ≤ 0.001). G-glutamyltransferase activity is inversely related to protein content with molecular weights of 43 kD, 52 kD, 66 kD, 87 kD, and 100 kD and 155 kD (P ≤ 0.001). The Ca2+, Mg2+-ATPase of the basolateral membrane activity of enterocytes is directly related to the protein amount with molecular weights of 26 kD (P ≤ 0.01), Mg2+-ATPase and Mg2+-ATPase with protein content with the molecular value of 100 kD (P ≤ 0.05).
Desempenho agronômico de cultivares de batata-doce (Ipomoea batatas) em Iporá -Goiás
Authors: Cajango Talita Cavalcante , Alves Estenio Moreira , Calgaro Junior Guido , Paim Tiago do Prado , Claudio Flavio Lopes 
Published: June 2021

O desempenho de diferentes genótipos é diferente conforme ambiente e processo produtivo empregado, conhecer esse comportamento é fundamental para obtenção de boas produtividades. Nesse sentido, objetivou-se avaliar o desempenho agronômico e produtivo de diferentes tipos de cultivares de batata-doce, visando a seleção de cultivares mais produtivos voltados a alimentação humana. Desenvolveu-se um experimento, no ano de 2014, composto por nove cultivares no delineamento em blocos casualizados (DBC), com três repetições. Avaliou-se as características de produtividade, formato da raiz, massa, comprimento, diâmetro e os resíduos, quantificando assim as raízes não comerciais. As cultivares Brazlandia Roxa, Rubssol, Brazlandia Branca, Beauregard e Princesa obtiveram maior desempenho agronômico. Dessa forma essas variedades não se diferiram e apresentaram características interessantes a serem exploradas para a produção destinada a alimentação humana pelo seu desempenho agronômico e de produção, porém a escolha deve ser levada em consideração a facilidade de implantação e o mercado consumidor que deseja atingir.
Acute Kidney Injury is Aggravated in Aged Mice by the Exacerbation of Proinflammatory Processes
Authors: Marquez-Exposito Laura , Tejedor-Santamaria Lucia , Santos-Sanchez Laura , Valentijn Floris A. , Cantero-Navarro Elena , Rayego-Mateos Sandra , Rodrigues-Diez Raul R. , Tejera-Muñoz Antonio , Marchant Vanessa , Sanz Ana B. , Ortiz Alberto , Goldschmeding Roel , Ruiz-Ortega Marta 
Published: June 2021

Acute kidney injury (AKI) is more frequent in elderly patients. Mechanisms contributing to AKI (tubular cell death, inflammatory cell infiltration, impaired mitochondrial function, and prolonged cell-cycle arrest) have been linked to cellular senescence, a process implicated in regeneration failure and progression to fibrosis. However, the molecular and pathological basis of the age-related increase in AKI incidence is not completely understood. To explore these mechanisms, experimental AKI was induced by folic acid (FA) administration in young (3-months-old) and old (1-year-old) mice, and kidneys were evaluated in the early phase of AKI, at 48 h. Tubular damage score, KIM-1 expression, the recruitment of infiltrating immune cells (mainly neutrophils and macrophages) and proinflammatory gene expression were higher in AKI kidneys of old than of young mice. Tubular cell death in FA-AKI involves several pathways, such as regulated necrosis and apoptosis. Ferroptosis and necroptosis cell-death pathways were upregulated in old AKI kidneys. In contrast, caspase-3 activation was only found in young but not in old mice. Moreover, the antiapoptotic factor BCL-xL was significantly overexpressed in old, injured kidneys, suggesting an age-related apoptosis suppression. AKI kidneys displayed evidence of cellular senescence, such as increased levels of cyclin dependent kinase inhibitors p16ink4a and p21cip1, and of the DNA damage response marker γH2AX. Furthermore, p21cip1 mRNA expression and nuclear staining for p21cip1 and γH2AX were higher in old than in young FA-AKI mice, as well as the expression of senescence-associated secretory phenotype (SASP) components (Il-6, Tgfb1, Ctgf, and Serpine1). Interestingly, some infiltrating immune cells were p21 or γH2AX positive, suggesting that molecular senescence in the immune cells (“immunosenescence”) are involved in the increased severity of AKI in old mice. In contrast, expression of renal protective factors was dramatically downregulated in old AKI mice, including the antiaging factor Klotho and the mitochondrial biogenesis driver PGC-1α. In conclusion, aging resulted in more severe AKI after the exposure to toxic compounds. This increased toxicity may be related to magnification of proinflammatory-related pathways in older mice, including a switch to a proinflammatory cell death (necroptosis) instead of apoptosis, and overactivation of cellular senescence of resident renal cells and infiltrating inflammatory cells.
Novel Magnetic Resonance Imaging-Based Method for Accurate Diagnosis of Meniere's Disease
Authors: Ito Taeko , Inoue Takashi , Inui Hiroshi , Miyasaka Toshiteru , Yamanaka Toshiaki , Kichikawa Kimihiko , Takeda Noriaki , Kasahara Masato , Kitahara Tadashi , Naganawa Shinji 
Published: June 2021

Background: Pathologically, Meniere's disease symptoms are considered to be associated with endolymphatic hydrops. Examinations revealing endolymphatic hydrops can be useful for accurate Meniere's disease diagnosis. We previously reported a quantitative method for evaluating endolymphatic hydrops, i.e., by measuring the volume of the endolymphatic space using three-dimensional magnetic resonance imaging (MRI) of the inner ear. This study aimed to confirm the usefulness of our methods for diagnosing Meniere's disease. Here, we extracted new explanatory factors for diagnosing Meniere's disease by comparing the volume of the endolymphatic space between healthy volunteers and patients with Meniere's disease. Additionally, we validated our method by comparing its diagnostic accuracy with that of the conventional method.Methods and Findings: This is a prospective diagnostic accuracy study performed at vertigo/dizziness centre of our university hospital, a tertiary hospital. Eighty-six patients with definite unilateral Meniere's disease and 47 healthy volunteers (25 and 33 males, and 22 and 53 females in the control and patient groups, respectively) were enrolled. All participants underwent 3-Tesla MRI 4 h after intravenous injection of gadolinium to reveal the endolymphatic space. The volume of the endolymphatic space was measured and a model for Meniere's disease diagnosis was constructed and compared with models using conventional criteria to confirm the effectiveness of the methods used. The area under the receiver operating characteristic curve of the method proposed in this study was excellent (0.924), and significantly higher than that derived using the conventional criteria (0.877). The four indices, sensitivity, specificity, positive predictive value, and negative predictive value, were given at the threshold; all of these indices achieved higher scores for the 3D model compared to the 2D model. Cross-validation of the models revealed that the improvement was due to the incorporation of the semi-circular canals.Conclusions: Our method showed high diagnostic accuracy for Meniere's disease. Additionally, we revealed the importance of observing the semi-circular canals for Meniere's disease diagnosis. The proposed method can contribute toward providing effective symptomatic relief in Meniere's disease.
Brainstem Quadruple Aberrant Hyperphosphorylated Tau, Beta-Amyloid, Alpha-Synuclein and TDP-43 Pathology, Stress and Sleep Behavior Disorders
Authors: Calderón-Garcidueñas Lilian , Rajkumar Ravi Philip , Stommel Elijah W. , Kulesza Randy , Mansour Yusra , Rico-Villanueva Adriana , Flores-Vázquez Jorge Orlando , Brito-Aguilar Rafael , Ramírez-Sánchez Silvia , García-Alonso Griselda , Chávez-Franco Diana A. , Luévano-Castro Samuel C. , García-Rojas Edgar , Revueltas-Ficachi Paula , Villarreal-Ríos Rodolfo , Mukherjee Partha S. 
Published: June 2021

Quadruple aberrant hyperphosphorylated tau (p-τ), amyloid-β peptide, alpha-synuclein and TDP-43 brainstem and supratentorial pathology are documented in forensic ≤40y autopsies in Metropolitan Mexico City (MMC), and p-τ is the major aberrant protein. Post-traumatic stress disorder (PTSD) is associated with an elevated risk of subsequent dementia, and rapid eye movement sleep behavior disorder (RBD) is documented in PD, AD, Lewy body dementia and ALS. This study aimed to identify an association between PTSD and potential pRBD in Mexico. An anonymous online survey of 4502 urban college-educated adults, 29.3 ± 10.3 years; MMC, n = 1865; non-MMC, n = 2637, measured PTSD symptoms using the Impact of Event Scale–Revised (IES-R) and pRBD symptoms using the RBD Single-Question. Over 50% of the participants had IES-R scores ≥33 indicating probable PTSD. pRBD was identified in 22.6% of the participants across Mexico and 32.7% in MMC residents with PTSD. MMC subjects with PTSD had an OR 2.6218 [2.5348, 2.7117] of answering yes to the pRBD. PTSD and pRBD were more common in women. This study showed an association between PTSD and pRBD, strengthening the possibility of a connection with misfolded proteinopathies in young urbanites. We need to confirm the RBD diagnosis using an overnight polysomnogram. Mexican women are at high risk for stress and sleep disorders.
Ultrasonik Cihazlarla Yağ Alma Ameliyatının İntraoperatif Subkutan Radyofrekans Uygulamasıyla Kombine Edilmesi
Authors: CELİK Naci 
Published: June 2021

Giriş ve Amaç: Liposuction ameliyatı bir kilo verme yöntemi olmayıp vücut kontur bozukluğunu düzeltmek için yapılan bir işlemdir. Ancak kontur bozukluğu olan her birey liposuction için uygun bir aday olmayabilir. Liposcution’ın önemli bir kontrendikasyonu derinin gevşekliğidir. Her ne kadar son 10 yıldır yaygın şekilde kullanılan üçüncü jenerasyon ultrasonik cihazlar, deriden yüzeyel yağ alınmasına izin verdiği için bir miktar deride sıkılaşma yapsa da bu yeterli olmamakta ve pek çok hasta liposuction için uygun bulunmamaktadır. Bu noktada termal enerji ile fibroseptal ağı uyaran radyofrekans cihazları iyi bir alternatif olabilir.
Gereç ve Yöntemler: Deri yapısı gevşek ve liposuction için ideal aday olmayan 7 erkek 3 kadın hasta bu çalışmaya alınmıştır. Bu hastalara ultrasonik liposuction uygulanarak yağ alınmış ve bu işlemin ardından da subkutan plasma radyofrekans uygulanarak deride sıkılaşma sağlanması amaçlanmıştır. Daha sonra hastalar kontrollere çağrılarak fotoğrafları çekilmiş ve hasta memnuniyetleri araştırılmıştır.
Bulgular: Ameliyat sırasında hastaların tamamında radyofrekans uygulanması sonrası deride sıkılaşma başladığı görülmüş ve bu etkinin ilk 3 ay boyunca arttığı gözlenmiştir. Yazar, derinin sıkılaşması sübjektif bir bulgu olduğu için sıkılaşma miktarını anlayabilmek için, ameliyat öncesi ve sonrası fotoğrafları incelemiş ve daha önemlisi hastaların verilen anket sorularına cevaplarını değerlendirmiştir.
Sonuç: Teknolojik liposuction diyebileceğimiz ultrason+radyofrekans kombinasyonu normalde liposuction için uygun olmayan, derisi gevşek hastalarda, ideal bir kombinasyon oluşturma açısından umut verici görünmektedir.
DEVELOPMENT OF A BINARY INSTALLATION DISPATCH SYSTEM BASED ON THE SIEMENS TIA PORTAL SOFTWARE
Authors: Пашаев В.В. , Исаева М.Р. , Лабазанов М.А. 
Published: June 2021

В данной работе представлены результаты исследований, связанные с возможностью реализации бинарной установки генерации электроэнергии для самообеспечения геотермальной станции на основе реализации циркуляционной схемы использования глубинного тепла Земли (ГСЦС). Авторами рассмотрена схема бинарной установки с включением экономайзера. Разработанная программа пользовательского интерфейса предназначена для реализации человеко-машинного интерфейса автоматизированной системы управления и контроля опытно-промышленной геотермальной станции на основе реализации циркуляционной схемы использования глубинного тепла Земли. Произведен подбор аппаратно-технических и программных средств для выполнения программы.
This article presents the results of studies related to the possibility of implementing a binary installation of electricity generation for self-support of a geothermal station based on the implementation of the circulation scheme for using the Earths deep heat (GSCS). The authors considered a binary installation scheme with the economizer on. The developed user interface program is designed to implement a human-machine interface of an automated control and monitoring system for a pilot industrial geothermal station based on the implementation of the circulation scheme for using the Earths deep heat. The selection of hardware and software and software for the program.
AUTOMATION OF THE STEAM PRODUCTION FOR DOMESTIC AND INDUSTRIAL CONSUMERS
Authors: Амхадов М.А. , Сусуркаев Х.Н. , Садыков Х.А. 
Published: June 2021

В статье рассматривается производство пара как объект автоматизации, представлены материалы по основным подходам при автоматизации производства пара, рассматриваются принципы формирования схемы управления, а также структура системы управления. Рассматриваются проблемы, возникающие при передаче произведенного пара на расстояние. Описываются параметры для контроля, регулирования, сигнализации и блокировки для оптимального управления котлоагрегатами. Анализируются применяемые приборы и средства автоматизации, программные средства, включая интегрированную систему проектирования и управления TRACE MODE. Рассматривается пример автоматизации парогенератора Грозненского завода железобетонных изделий в виде разработанных окон в TRACE MODE 6.0.
The article deals with the production of steam as an object of automation, presents materials on the main approaches to the automation of steam production, discusses the principles of formation of the control scheme, as well as the structure of the control system. The problems arising in the transmission of produced steam over a distance are considered. Parameters for control, regulation, signalling and interlocking for optimum boiler control are described. The applied devices and means of automation, software, including the integrated system of design and control of TRACE MODE are analyzed. The authors describe the case study of automation of a steam generator of the Grozny concrete products plant in the form developed by Windows in TRACE MODE 6.0.