bluuebunny/crossref_metadata_2025_split huggingface dataset:
Racism and Nationalism
Authors: Rutland Peter 
Published: December 2021

AbstractThis article reviews the current scholarship around racism and nationalism, two of the mostly hotly debated issues in contemporary politics. Both racism and nationalism involve dividing humanity into groups and setting up some groups as innately superior to others. Until recently, racism and nationalism were both widely seen as unpleasant relics of times past, destined to disappear as the principles of equality and human rights become universally embraced. But both concepts have proved their resilience in recent years. Scholars have been devoting new attention to the “racialization” of ethnic and national identities in the former Soviet Union and East Europe, the regions that are the main focus of this journal. The article examines the prevailing approaches to understanding the terms “racism” and “nationalism,” which are distinct but overlapping categories of analysis and vehicles of political mobilization. Developments in genomics have complicated the relationship between perceptions of race as a purely social phenomenon. The essay explores the way racism and nationalism play out in two self-proclaimed “exceptional” political systems – the Soviet Union and the United States – which have played a prominent role in global debates about race and nation. It briefly discusses developments in other regions, such as the debate over multiculturalism in Europe.
Rejoinder: Concluding Remarks on Scholarly Communications
Authors: Katz Jonathan N. , King Gary , Rosenblatt Elizabeth 
Published: December 2021

AbstractWe are grateful to DeFord et al. for the continued attention to our work and the crucial issues of fair representation in democratic electoral systems. Our response (Katz, King, and Rosenblatt Forthcoming) was designed to help readers avoid being misled by mistaken claims in DeFord et al. (Forthcoming-a), and does not address other literature or uses of our prior work. As it happens, none of our corrections were addressed (or contradicted) in the most recent submission (DeFord et al. Forthcoming-b).
Self-blame in major depression: a randomised pilot trial comparing fMRI neurofeedback with self-guided psychological strategies
Authors: Jaeckle Tanja , Williams Steven C. R. , Barker Gareth J. , Basilio Rodrigo , Carr Ewan , Goldsmith Kimberley , Colasanti Alessandro , Giampietro Vincent , Cleare Anthony , Young Allan H. , Moll Jorge , Zahn Roland 
Published: December 2021

AbstractBackgroundOvergeneralised self-blame and worthlessness are key symptoms of major depressive disorder (MDD) and have previously been associated with self-blame-selective changes in connectivity between right superior anterior temporal lobe (rSATL) and subgenual frontal cortices. Another study showed that remitted MDD patients were able to modulate this neural signature using functional magnetic resonance imaging (fMRI) neurofeedback training, thereby increasing their self-esteem. The feasibility and potential of using this approach in symptomatic MDD were unknown.MethodThis single-blind pre-registered randomised controlled pilot trial probed a novel self-guided psychological intervention with and without additional rSATL-posterior subgenual cortex (BA25) fMRI neurofeedback, targeting self-blaming emotions in people with insufficiently recovered MDD and early treatment-resistance (n = 43, n = 35 completers). Participants completed three weekly self-guided sessions to rebalance self-blaming biases.ResultsAs predicted, neurofeedback led to a training-induced reduction in rSATL-BA25 connectivity for self-blame v. other-blame. Both interventions were safe and resulted in a 46% reduction on the Beck Depression Inventory-II, our primary outcome, with no group differences. Secondary analyses, however, revealed that patients without DSM-5-defined anxious distress showed a superior response to neurofeedback compared with the psychological intervention, and the opposite pattern in anxious MDD. As predicted, symptom remission was associated with increases in self-esteem and this correlated with the frequency with which participants employed the psychological strategies in daily life.ConclusionsThese findings suggest that self-blame-rebalance neurofeedback may be superior over a solely psychological intervention in non-anxious MDD, although further confirmatory studies are needed. Simple self-guided strategies tackling self-blame were beneficial, but need to be compared against treatment-as-usual in further trials. https://doi.org/10.1186/ISRCTN10526888
Language socialization and academic discourse in English as a Foreign Language contexts: A research agenda
Authors: Friedman Debra A. 
Published: December 2021

AbstractIn this paper, I argue for expanding language socialization research on the academic discourse socialization of speakers of English as an additional language to less-commonly researched settings outside of English-dominant countries. Following an overview of some theoretical and methodological issues involved in conducting such research, I lay out a research agenda, focusing on several topics and issues that have the potential to illuminate issues of interest in both language socialization and second language acquisition regarding howcompetenceandcommunityare defined in a globalized, multilingual world. These include: (a) closer investigation of presumed ‘cultural differences’ between ‘Western’ and ‘Asian’ academic discourse practices, (b) the effect of social categories such as ethnicity and ‘nonnative speaker’ status on the construction of ‘expert’ and ‘novice’ identities in these settings, (c) the role of socializing agents outside of the classroom, and (d) the extent to which students in these settings are being socialized into practices and ideologies that promote multicompetence.
Follicular development, morphological integrity, and oxidative stress in bovine preantral follicles cultured in vitro with ascorbic acid
Authors: Bergamo Larissa Zamparone , Bonato Denis Vinicius , Bizarro-Silva Camila , Bonato Francieli Gesleine Capote , Sanches Tamires Korchovei , Cerezetti Marcela Bortoletto , Rossaneis Ana Carolina , Verri Waldiceu A. , Morotti Fábio , Seneda Marcelo Marcondes 
Published: December 2021

SummaryThe aim of this study was to evaluate the follicular development, morphological integrity, and oxidative stress of preantral ovarian follicles from Bos taurus indicus females grown in vitro with ascorbic acid. Ovaries (n = 20) from Bos taurus indicus females were collected, fragmented, and were cultured in vitro for 6 or 12 days in minimum essential medium (MEM), or MEM supplemented with 50 or 100 ng/ml ascorbic acid, with an extracellular matrix of agarose gel, in an incubator at 38.5°C; every 2 days, 100% of the culture medium was replaced. The data were analyzed using the chi-squared test and/or Fisher’s exact test. In the event of a significant effect, the proportions were compared using a 2 × 2 proportion test. The oxidative stress analysis data were submitted to analysis of variance followed by the Bonferroni test. Values were considered significant when P ≤ 0.05. The addition of 100 ng/ml of ascorbic acid to the in vitro culture medium of preantral ovarian follicles from bovine females promoted follicular development, was efficient in maintaining morphological integrity, as well as the stability of reactive oxygen species, after 6 days of in vitro culture.
A transdiagnostic model of low self-esteem: pathway analysis in a heterogeneous clinical sample
Authors: Kresznerits Szilvia , Rózsa Sándor , Perczel-Forintos Dóra 
Published: December 2021

AbstractBackground:Low self-esteem (LSE) has been associated with several psychiatric disorders, and is presumably influenced by transdiagnostic factors. Our study was based both on investigations of the relationship between depression and LSE (vulnerability, scar, reciprocal models) and on theories of cognitive factors contributing to the development and maintenance of LSE, such as Melanie Fennell’s model, the catalyst model and the Self-Regulatory Executive Function model.Aims:Based on the theories above, in our cross-sectional study we aimed at understanding more specifically the transdiagnostic factors that can maintain LSE in a heterogeneous clinical sample.Method:Six hundred and eleven out-patients were assessed by SCID-I and self-report questionnaires. The model was tested by structural equation modelling.Results:Based on the fit indices, the hypothesis model did not fit the data; therefore, a modified transdiagnostic model was emerged. This model made a good fit to the data [χ2 (12, n=611)=76.471, p<.001; RMSEA=.080, CFI=.950, TLI=.913] with a strong explanatory power (adj R2=.636). Severe stressful life events and depressive symptoms lead to LSE indirectly. Self-blame, perfectionism, seeking love and hopelessness have been identified as mediating factors in the relationship between depressive symptoms and LSE. Although there was a significant correlation between state-anxiety and LSE, as well as LSE and rumination, these two factors did not fit into the model.Conclusions:The new transdiagnostic model of LSE has great potential in the treatment of various mental conditions and may serve as a guide to developing more focused and more effective therapeutic interventions.
Solidarity in diversity: online petitions and collective identity in Hong Kong's Anti-Extradition Bill Movement
Authors: Yuen Samson , Tong Kin-long 
Published: December 2021

AbstractCollective identity is a key catalyst of protest mobilization. How does collective identity come into existence among strangers with diverse backgrounds, especially in movements without a centralized leadership? Although collective identity is often seen as something constructed by movement organizations or out of established networks, we describe a more bottom-up and decentralized process in which movement collective identity is created through the horizontal mobilization of intermediate identities, which leverage pre-existing social identifications to induce commitment among individuals. Focusing on Hong Kong's Anti-Extradition Bill Movement of 2019, we argue that online petitions against the controversial bill created intermediate group identities among myriad social groups, such as alumni, professions, hobby groups, and residential communities. These intermediate identities provided rich discursive resources for previously disconnected individuals to collectively perceive the threat of the bill and see the obligation to act, which, in turn, shaped a strong collective identity early on in the protests. Our findings may help contribute to a more nuanced understanding of collective identity formation in contemporary leaderless movements.
Experience, Knowledge, and Political Representation
Authors: Allen Peter 
Published: December 2021

AbstractEvidence suggests that increasing the descriptive representation of groups improves their substantive representation. What underpins this link? Many scholars writing on the subject stop short of arguing explicitly that it is “shared experience” within groups. I argue that we should embrace the potential conceptual and empirical benefits of framing representation through experience. To do this, we should think of experience specifically in terms of the epistemic content and capacities gained through subjective experience, which can allow individuals to think about the world in distinct ways. I reframe the idea that experiences might be shared within groups and ameliorate concerns that the concept is essentialist, drawing out the political relevance of my argument. This has the strategic implication that we should be unafraid to argue in favor of political presence on the basis of (shared) experience and the empirical implication that future research should consider subjective experience more closely.
CONCILIATORY REASONING, SELF-DEFEAT, AND ABSTRACT ARGUMENTATION
Authors: KNOKS ALEKS 
Published: December 2021

AbstractAccording to conciliatory views on the significance of disagreement, it’s rational for you to become less confident in your take on an issue in case your epistemic peer’s take on it is different. These views are intuitively appealing, but they also face a powerful objection: in scenarios that involve disagreements over their own correctness, conciliatory views appear to self-defeat and, thereby, issue inconsistent recommendations. This paper provides a response to this objection. Drawing on the work from defeasible logics paradigm and abstract argumentation, it develops a formal model of conciliatory reasoning and explores its behavior in the troubling scenarios. The model suggests that the recommendations that conciliatory views issue in such scenarios are perfectly reasonable—even if outwardly they may look odd.
Non‐Singular Calculation of Geomagnetic Vectors and Geomagnetic Gradient Tensors
Authors: Liu Xiaogang , Xu Tianhe , Sun Bijiao , Li Xinxing , Wang Yunpeng , Guan Bin 
Published: December 2021

AbstractSome spherical harmonic expressions of gravitational and geomagnetic field elements will become infinite when computation point approaches polar regions, as the sine function of the geocentric co‐latitude contained in the denominator tends to be zero. Currently, this singularity problem has been solved for gravitational field case, however, it remains unsolved for geomagnetic vectors (GVs) and geomagnetic gradient tensors (GGTs). Because the latter use Schmidt semi‐normalized associated Legendre function (SNALF), which is different from fully‐normalized associated Legendre function used in the former. To overcome this singularity problem, we derive new non‐singular expressions of the first‐ and second‐order derivatives of Schmidt SNALF (order m equals to 0 or 1), and the corresponding two kinds of spherical harmonic polynomials. When the non‐singular expressions are applied to the traditional formulae of GVs and GGTs, more practical expressions of GVs and GGTs with non‐singularity are formulated by refining the cases that the order m equals to 0, 1, 2 and other values. Furthermore, to provide flexible calculation strategies for Schmidt SNALF, we derive four kinds of recursive formulae, including the standard forward row recursion, the standard forward column recursion, the cross degree and order recursion, and the Belikov recursion. The standard formula to check the calculation accuracy of various recursive formulae of SNALF are also given. Besides, we demonstrate the effectiveness and reliability of the new derived non‐singular expressions of GVs and GGTs and analyze the computation speed and stability of the four recursive formulae by extensive numerical experiments.
Trends and Rhythms in Climate Change During the Early Permian Icehouse
Authors: Fang Qiang , Wu Huaichun , Shen Shu‐zhong , Zhang Shihong , Yang Tianshui , Wang Xiangdong , Chen Jun 
Published: December 2021

AbstractLate Paleozoic deglaciation is the first icehouse‐to‐greenhouse transition in a world with expansive tropical forests, but the detailed process of this climatic upheaval is still debated due to lack of high‐precision global correlation. Here, based on the cyclostratigraphic analysis of a deep‐marine succession of Naqing in South China, chronostratigraphic correlation was achieved between Paleo‐Tethyan deep‐marine carbonate cyclicity and U‐Pb zircon age‐calibrated cyclothems from the Pangaean paleotropics. Refining the global chronostratigraphy indicates ages of 294.1 ± 0.2 Ma and 290.1 ± 0.2 Ma for the base of the Sakmarian and Artinskian stages, respectively. We juxtapose the climatic proxies and indicators across blocks and latitudes to decipher the trends and rhythms in climate change during a period from the apex of the Late Paleozoic ice age (LPIA) to the initial deglaciation. On the multiple‐million‐year time scale, the polar and equatorial climates were linked through the atmospheric pCO2 control. A rise in pCO2 promoted Gondwanan deglaciation and tropical aridification. The disparity in the inferred polarity of tropical climate changes during glacials and interglacials has been confirmed on the million‐year time scale. The meridional flux of moisture was enhanced during the minima of the ∼1.2 Myr obliquity cycle, periodically resulting in Gondwanan glaciation, glacio‐eustatic sea‐level lowerings, and reduced moisture availability in the tropical Pangaean and Paleo‐Tethyan regions. Our study provides an improved temporal resolution and understanding of the apex of the LPIA.
LncRNA HSPA7 in human atherosclerotic plaques sponges miR-223 and promotes the proinflammatory vascular smooth muscle cell transition
Authors: Ann Soo-jin , Bang Hyoeun , Lee Chan Joo , Oh Jaewon , Park Sungha , Kang Seok-Min , Choi Jung Kyoon , Lee Sang-Hak 
Published: December 2021

AbstractAlthough there are many genetic loci in noncoding regions associated with vascular disease, studies on long noncoding RNAs (lncRNAs) discovered from human plaques that affect atherosclerosis have been highly limited. We aimed to identify and functionally validate a lncRNA using human atherosclerotic plaques. Human aortic samples were obtained from patients who underwent aortic surgery, and tissues were classified according to atherosclerotic plaques. RNA was extracted and analyzed for differentially expressed lncRNAs in plaques. Human aortic smooth muscle cells (HASMCs) were stimulated with oxidized low-density lipoprotein (oxLDL) to evaluate the effect of the identified lncRNA on the inflammatory transition of the cells. Among 380 RNAs differentially expressed between the plaque and control tissues, lncRNA HSPA7 was selected and confirmed to show upregulated expression upon oxLDL treatment. HSPA7 knockdown inhibited the migration of HASMCs and the secretion and expression of IL-1β and IL-6; however, HSPA7 knockdown recovered the oxLDL-induced reduction in the expression of contractile markers. Although miR-223 inhibition promoted the activity of Nf-κB and the secretion of inflammatory proteins such as IL-1β and IL-6, HSPA7 knockdown diminished these effects. The effects of miR-223 inhibition and HSPA7 knockdown were also found in THP-1 cell-derived macrophages. The impact of HSPA7 on miR-223 was mediated in an AGO2-dependent manner. HSPA7 is differentially increased in human atheroma and promotes the inflammatory transition of vascular smooth muscle cells by sponging miR-223. For the first time, this study elucidated the molecular mechanism of action of HSPA7, a lncRNA of previously unknown function, in humans.
The impact of obesity and bariatric surgery on the immune microenvironment of the endometrium
Authors: Naqvi Anie , MacKintosh Michelle L. , Derbyshire Abigail E. , Tsakiroglou Anna-Maria , Walker Thomas D. J. , McVey Rhona J. , Bolton James , Fergie Martin , Bagley Steven , Ashton Garry , Pemberton Philip W. , Syed Akheel A. , Ammori Basil J. , Byers Richard , Crosbie Emma J. 
Published: December 2021

Abstract
Background
The incidence of endometrial cancer is rising in parallel with the obesity epidemic. Obesity increases endometrial cancer risk and weight loss is protective, but the underlying mechanisms are incompletely understood. We hypothesise that the immune microenvironment may influence susceptibility to malignant transformation in the endometrium. The aim of this study was to measure the impact of obesity and weight loss on the immunological landscape of the endometrium.

Methods
We conducted a prospective cohort study of women with class III obesity (body mass index, BMI ≥ 40 kg/m2) undergoing bariatric surgery or medically-supervised low-calorie diet. We collected blood and endometrial samples at baseline, and two and 12 months after weight loss intervention. Serum was analysed for inflammatory markers CRP, IL-6 and TNF-α. Multiplex immunofluorescence was used to simultaneously identify cells positive for immune markers CD68, CD56, CD3, CD8, FOXP3 and PD-1 in formalin-fixed paraffin-embedded endometrial tissue sections. Kruskal–Wallis tests were used to determine whether changes in inflammatory and immune biomarkers were associated with weight loss.

Results
Forty-three women with matched serum and tissue samples at all three time points were included in the analysis. Their median age and BMI were 44 years and 52 kg/m2, respectively. Weight loss at 12 months was greater in women who received bariatric surgery (n = 37, median 63.3 kg) than low-calorie diet (n = 6, median 12.8 kg). There were significant reductions in serum CRP (p = 3.62 × 10−6, r = 0.570) and IL-6 (p = 0.0003, r = 0.459), but not TNF-α levels, with weight loss. Tissue immune cell densities were unchanged except for CD8+ cells, which increased significantly with weight loss (p = 0.0097, r = −0.323). Tissue CD3+ cell density correlated negatively with systemic IL-6 levels (p = 0.0376; r = −0.318).

Conclusion
Weight loss is associated with reduced systemic inflammation and a recruitment of protective immune cell types to the endometrium, supporting the concept that immune surveillance may play a role in endometrial cancer prevention.
In vitro interaction network of a synthetic gut bacterial community
Authors: Weiss Anna S , Burrichter Anna G , Durai Raj Abilash Chakravarthy , von Strempel Alexandra , Meng Chen , Kleigrewe Karin , Münch Philipp C , Rössler Luis , Huber Claudia , Eisenreich Wolfgang , Jochum Lara M , Göing Stephanie , Jung Kirsten , Lincetto Chiara , Hübner Johannes , Marinos Georgios , Zimmermann Johannes , Kaleta Christoph , Sanchez Alvaro , Stecher Bärbel 
Published: December 2021

Abstract
A key challenge in microbiome research is to predict the functionality of microbial communities based on community membership and (meta)-genomic data. As central microbiota functions are determined by bacterial community networks, it is important to gain insight into the principles that govern bacteria-bacteria interactions. Here, we focused on the growth and metabolic interactions of the Oligo-Mouse-Microbiota (OMM12) synthetic bacterial community, which is increasingly used as a model system in gut microbiome research. Using a bottom-up approach, we uncovered the directionality of strain-strain interactions in mono- and pairwise co-culture experiments as well as in community batch culture. Metabolic network reconstruction in combination with metabolomics analysis of bacterial culture supernatants provided insights into the metabolic potential and activity of the individual community members. Thereby, we could show that the OMM12 interaction network is shaped by both exploitative and interference competition in vitro in nutrient-rich culture media and demonstrate how community structure can be shifted by changing the nutritional environment. In particular, Enterococcus faecalis KB1 was identified as an important driver of community composition by affecting the abundance of several other consortium members in vitro. As a result, this study gives fundamental insight into key drivers and mechanistic basis of the OMM12 interaction network in vitro, which serves as a knowledge base for future mechanistic in vivo studies.