bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quem a homotransfobia matou hoje? Uma leitura comparada dos relatórios de mortes violentas de LGBT+ (2011-2019)
Authors: Santos Éverton de Jesus , Silva Carlos André Lima 
Published: February 2021

RESUMO: Segundo dados de 2019 apresentados pelo Grupo Gay da Bahia (GGB) e pela hemeroteca digital “Homotransfobia mata”, a cada 26 horas uma pessoa LGBT+ morre no Brasil por suicídio ou homicídio, fruto da homotransfobia estrutural existente no país. Diante desse cenário de negligência humana e jurídica por parte do Estado para com as vidas e a existência dessa população, além da exclusão, pelo MEC, de temas relacionados a gênero e orientação/diversidade sexual na Base Nacional Comum Curricular (2017), este estudo pretende sistematizar, de forma comparativa e a partir de uma abordagem baseada mais especificamente no amplo relatório divulgado em 2019, os dados constantes nos relatórios publicados de 2011 a 2019, os quais mapeiam as mortes violentas de LGBT+ levantadas pela parceria entre o GGB (presidido por Luiz Mott), Eduardo Michels (autor da pesquisa) e colaboradores. A partir disso, é possível criar um painel da homofobia e da transfobia ao longo da última década no Brasil, observando-se os índices de assassinatos e suicídios, bem como os números de casos por região, cor/raça, idade, profissão e causa mortis. O ponto de partida é o artigo 5º da Carta Magna de 1988 no tocante à igualdade, à ausência de distinção e à inviolabilidade dos direitos, além da criminalização pelo Supremo Tribunal Federal, em 2019, da LGBTfobia, tendo em vista assegurar, de maneira mais incisiva, o mínimo humanitário no que diz respeito à proteção de um grupo histórica e culturalmente vulnerável e estigmatizado. Isto posto, cabem, entre outras medidas, a conscientização dos brasileiros quanto aos direitos humanos, o incentivo à denúncia dos crimes contra as minorias sexuais e sua efetiva investigação, elucidação e punição, além da promoção, na escola, de debates sobre gênero e orientação/diversidade sexual e de abertura de mais postos de trabalho formais para LGBT+.
PALAVRAS-CHAVE: Homicídios e suicídios, minorias sexuais, painel da LGBTfobia.
Educação de Jovens Adultos e Idosos - sujeitos de direitos de uma educação político-pedagógica
Authors: Borba Sara Ingrid 
Published: February 2021

RESUMO: O presente texto resulta de estudos preliminares acerca da Educação de Jovens Adultos em um contexto que se percebe a existência e o forte discurso em defesa da Base Nacional Comum Curricular – BNCC, para os diversos níveis de educação Básica, elaboradas com vistas às novas demandas educacionais. Mas, vale questionar sobre o porquê a Educação de Jovens, Adultos – EJA não está sendo contemplada nesta nova implementação curricular e como fica a situação de seus sujeitos. Enquanto política pública de estado busca fortalecer os direitos de aprendizagem dos estudantes brasileiros, no entanto, não vemos contemplados os direitos dos sujeitos da EJA em consonância com as suas especificidades, inclusive, ressalta-se a discussão sobre a presença da pessoa idosa no contexto desta modalidade de ensino. A Educação de Jovens Adultos e Idosos - EJAI é garantia do direito de acesso à educação pública e de qualidade para aqueles que não tiveram condições de estudos na idade certa, previsto na Constituição Federal de 1988 e na LDB (9394/96), como também nas demais políticas públicas. Tomou-se, ainda, documentos do GT 18 da ANPED como ponto de partida para a reflexão crítica, bem como pesquisas já realizadas com este cunho de criticidade. Na reflexão sobre a relação da EJA e da Educação Popular como política própria, com seu currículo e suas próprias referências filosóficas e políticas, bem como seus fundamentos e as estratégias didático pedagógicas, as quais estão fundamentadas na perspectiva freiriana. Assim, foi realizada a pesquisa de cunho qualitativa tipo descritiva. Enquanto aspectos conclusivos apresenta proposições de ampliar a discussão sobre a educação popular na defesa da proposta de educação para todos, destacando a importância de considerar e respeitar os sujeitos da EJA, enquanto sujeitos de direitos em contraposição aos processos de negação e exclusão que permeiam esta modalidade de ensino da educação básica.
PALAVRAS-CHAVE: EJAI, BNCC, Direitos.
Pharmacoeconomic feasibility of using the drug Hemangiol (propranolol, oral solution) in the treatment of proliferating infantile hemangioma requiring systemic therapy
Authors: Dyakov I. N. , Varfolomeеva S. R. 
Published: February 2021

Aim. The study aimed to evaluate the pharmacoeconomic feasibility of propranolol application in the dosage form of the oral solution in the treatment of proliferating infantile hemangioma requiring systemic therapy.Materials and methods. The study design was a retrospective analysis of the published data. The methods of pharmacoeconomic analysis included a clinical-economic analysis (cost-effectiveness analysis) with a sensitivity analysis; and a "budget impact" analysis with a sensitivity analysis. The authors compared the pharmacoeconomic effectiveness of pharmacotherapy for infant hemangiomas with propranolol and surgical methods of treatment.Results. The efficacy of propranolol therapy was 39% higher than surgical methods of treatment. The relative increase in the efficacy of propranolol therapy compared to surgical treatments was 68.4%. At the same time, the cost of propranolol therapy was lower than the cost of surgical treatments by 31.7% or 56,486,07 RUR per patient per year. The application of propranolol in the treatment for proliferating infantile hemangioma allowed reducing the burden on the budget of the state guarantee program in comparison with surgical methods of treatment for 3 years by 1,562.0 million RUR with a proportion of 12% of patients with infant hemangiomas requiring systemic therapy (9,694 patients per year). The sensitivity analysis of the cost and effectiveness of the compared medical technologies showed that the obtained results are resistant to the fluctuations in these parameters in the range from − 20% to + 20%.Conclusion. The application of propranolol preparation in a dosage form of oral solution for the treatment of patients with proliferating infantile hemangioma will significantly increase the efficiency of therapy and reduce costs associated with the application of surgical methods of treatment.
Determinants of Satisfaction and Proper Management of Aged Population in Chapai Nawabgonj District in Bangladesh: Multivariate Approach
Authors: Shamsuzzaman Md. 
Published: February 2021

Improving the ability of the satisfaction and proper management to reach the aged population is important for health and essential to mitigate the income erosion consequences of ill health in Bangladesh. This study examined the satisfaction and proper management of the elderly of some identified disadvantages of aged populations; including the effect of poverty-focused nongovernmental development interventions. The objective of the study is to determine the more influential factors that are affecting the health status and living arrangements of the elderly. The data were collected by direct interview method from Chapai-Nawabgonj District, Bangladesh. The chi-square test and logistic regression model were used to fulfill the objective of this study. The results of this study reveal that among literate the majority percent aged population has at least primary education and slightly over half of them have secondary level education. The majority of the elderly people are low income, economically dependent, living with married children. Also, they are unhealthy to suffer from different kinds of illnesses like Lame, Gastric, Blood pressure, Paralysis, Diabetics, etc. A large number of people is taking treatment from M.B.B.S, and a small portion of people are taking treatment from Homeopathic and Ayurvedic physician. Despite their suffering, most of them do not get the proper care. Television, Newspaper, monthly income-expenditure, family member, and educational status are associated with the satisfaction of elderly people. The logistic regression model exposed that serious operation and proper management are the most major significant factors effects satisfaction. It also exposed that mental torture, a different shelter for the elderly are major significant factors effects proper management. The paper concludes by emphasizing the importance of enhancing local capacities to determine whether self-treatment is indicated, to investigate socio-economic background, or in cases where satisfaction and proper management is sought, to judge provider competence and evaluate whether basic needs are justified. The provision of pharmaceutical training to the full spectrum of satisfied providers is also recommended.
Retrospective analysis of difficulties during mastoid surgeries in tertiary referral center in Nepal
Authors: Neupane Yogesh , Kharel Bijaya , Dongol Kripa , Pradhananga Rabindra B. , Rayamajhi Pabina , Dutta Heempali 
Published: February 2021

<p class="abstract"><strong>Background:</strong> Complications can occur during and following mastoidectomy because of the variation in the temporal bone anatomy and surgical factors. The operating surgeon needs to be aware of potential difficulties and their clinical relevance to avoid the dread complication. This study aims to study various per-operative difficulties and complications encountered during mastoid surgery.</p><p class="abstract"><strong>Methods:</strong> A retrospective study was conducted, including 152 cases of chronic otitis media squamous type who underwent mastoidectomy from June 2017 to January 2019. Revision cases and cases with missing records on per-operative findings, early postoperative status, hearing assessment were excluded from the study. </p><p class="abstract"><strong>Results:</strong> Out of 152 cases, there were 80 males and 72 females with a mean of 27.5 years. Dural plate breach was recognized in 19 cases (12.5%) with iatrogenic injury in 16 cases. Breach of sinus plate and exposure of sigmoid sinus was noted in 11 cases (7.24%) and all were iatrogenic. Korner’s septum was noted in five cases (3.29%). The facial canal was dehiscence in 25 cases (16.4%) with the majority in the horizontal segment, but the sheath was intact in all cases. Immediate postoperative facial nerve palsy was seen in four cases (2.6%). Fistula in the lateral semi-circular canal was noted in two cases. Taste disturbance was noted in 13 cases. Local complications related to the surgical site was seen in 19 cases.</p><p class="abstract"><strong>Conclusions:</strong> The anatomic variations and surgical difficulty are common in mastoid surgery. The major complication rate is around 2-3% despite various mastoid variation and difficulties.</p>
Functional outcome of zone 5 to zone 8 extensor tendon injuries of hand managed with early active mobilization following repair using a static splint: an observational study
Authors: Bhattacharjee Sourav , Rasheed Ashir Abdul , Alex Binu 
Published: February 2021

<p class="abstract"><strong>Background:</strong> Injuries to extensor tendons of the hand are underrepresented in the literature compared to flexor tendons. The concept of early mobilization following extensor tendon repair emerged as previous strategies of static immobilization lead to frequent adhesions and poor outcome. In our study we assessed the functional outcome of early active mobilization after extensor tendon repair using a static splint. </p><p class="abstract"><strong>Methods:</strong> In this observational study 42 patients with 48 extensor tendon severances of the hand from zone 5 to 8 were selected. Following repair, early active mobilization with a static splint was done and the functional outcomes were assessed using the Dargan criteria. <strong></strong></p><p class="abstract"><strong>Results:</strong> After mobilizing for 4 weeks, out of total 48 patients, 18 (43%) had good outcomes, 19 (45%) had fair and 5 patients (12%) had poor outcome. After 6 weeks 14 patients (33.3%) had excellent, 20 patients (48%) had good and 6 patients (14%) had fair outcomes whereas only one patient (2.4%) had poor outcome. This result was statistically significant with a p value of 0.000.</p><p class="abstract"><strong>Conclusions:</strong> Early active mobilization following extensor tendon repair from zone 5 to 8 prevents adhesion around the repair site, leads to better post-operative outcome and faster recovery. Using a static splint along with a patient friendly, easily comprehensible rehabilitation protocol offers results comparable to the use of dynamic splints and requires fewer post-operative follow ups. The static splints being cheap, easy to construct are financially beneficial to the patients. </p>
¿Por qué en ocasiones los resultados de las encuestas de opinión se alejan de la realidad? Un análisis con escenarios en Python
Authors: Benavides Murillo Francisco , Jiménez Oviedo Byron 
Published: February 2021

Antes de la segunda ronda de las elecciones presidenciales costarricenses del año 2018 en Costa Rica, se realizaron varias encuestas de opinión con el fin de evaluar las preferencias del electorado. Las encuestadoras en Costa Rica indicaban, en algunos casos, un empate técnico entre el candidato de Restauración Nacional y el del Partido Acción Ciudadana, y en otros casos una clara preferencia por el primero. El resultado final de las elecciones fue muy diferente al de estos estudios, y el triunfo del candidato del partido Acción Ciudadana fue claro y totalmente alejado de los márgenes de error asociados con la mayoría de los resultados obtenidos por las empresas encuestadoras. A raíz de esto, una pregunta natural surge: ¿por qué fallan las encuestas electorales? Uno de los argumentos utilizados es que las encuestas fueron realizadas con al menos una semana de antelación a las votaciones, y la opinión del electorado cambió en ese tiempo.
En el presente trabajo se plantean situaciones hipotéticas de posibles escenarios en los que el sesgo de las encuestas se puede presentar, así como una metodología para su detección. Se analiza, en particular, la tasa de respuesta de los encuestados y su influencia en las estimaciones de la encuesta. El hecho es que si los que apoyan a un determinado partido tienen una tendencia generalizada de no responder una encuesta, entonces los resultados de ésta serán sesgados, sin importar el momento en que se hagan las entrevistas. En este trabajo, los escenarios sintéticos son simulados computacionalmente utilizando Python por su interés didáctico. También se simulan métodos de ponderación para compensar estas deficiencias. Este artículo pretende abrir un espacio didáctico de discusión de los aspectos técnicos, matemáticos y computacionales de las encuestas de opinión nacionales, así como producir un escenario sintético computacional que pueda derribar algunos mitos populares frecuentes, como el mito de que sólo mil personas encuestadas no son suficientes para obtener una representación significativa de la opinión del electorado.
Ã‰tude Ethnobotanique Des Plantes UtilisÃ©es Dans Lâ€™artisanat Chez Les Agni Du Centre-Est Et Nord-Est De La CÃ´te dâ€™Ivoire
Authors: LÃ©opold Litta Amani , Lamine Diop Amadou , Bertin Kouakou Yao , FranÃ§ois Malan Djah 
Published: February 2021

Dans le but de valoriser le savoir traditionnel des plantes utilisÃ©es dans lâ€™artisanat, une enquÃªte ethnobotanique a Ã©tÃ© conduite chez quatre tribus Agni du Centre-est et du Nord-est de la CÃ´te dâ€™Ivoire. Les entretiens semi-structurÃ©s Ã travers lâ€™approche du Â« porte-Ã -porte Â» suivis de randonnÃ©es dans le milieu environnant ont permis dâ€™obtenir les informations sur lâ€™usage des plantes. Cette Ã©tude a montrÃ© que 104 espÃ¨ces rÃ©parties en 95 genres et 35 familles sont utilisÃ©es dans lâ€™artisanat. Pour ces quatre tribus, seulement 14,42% des plantes ont un indice dâ€™importance culturelle Ã©levÃ©. Il sâ€™agit entre autres de Baissea multiflora, Holarrhena floribunda, Mansonia altissima, Nauclea diderrichii, Nesogordonia papaverifera, Pseudocedrela kotschyi, etc. Lâ€™analyse du coefficient de Jaccard a montrÃ© des diffÃ©rences majeures au niveau de lâ€™usage des plantes entre ces quatre communautÃ©s, avec seulement 13,46% dâ€™usage commun. Il a Ã©tÃ© Ã©galement observÃ© que les savoirs liÃ©s aux plantes Ã usage artisanal sâ€™Ã©rodent progressivement, Ã cause notamment de lâ€™abondance des matÃ©riaux modernes et surtout de la rarÃ©faction des plantes utilisÃ©es due Ã la dÃ©gradation de lâ€™environnement.
An ethnobotanical survey was conducted among four Agni tribes in the central-eastern and north-eastern parts of CÃ´te dâ€™Ivoire. This study aimed to valorize the traditional knowledge of plants used in handicrafts. Semi-structured interviews through the "door-to-door" approach followed by walks in the adjacent vegetation provided information on the use of plants. This study showed that 104 species divided into 95 genera and 35 families are used in local handicrafts. For these four tribes, only 14.42% of the plants have a high index of cultural importance. These include Baissea multiflora, Holarrhena floribunda, Mansonia altissima, Nauclea diderrichii, Nesogordonia papaverifera, Pseudocedrela kotschyi etc. The analysis of Jaccard's coefficient showed differences in the use of plants between these four communities, with only 13.46% of these plants in common use. The knowledge related to plants for artisanal use is gradually deteriorating, for several reasons: obsolescence of uses, the unavailability of plants due to environmental degradation and competition with modern materials.
Vulnérabilité des terres des écosystèmes du domaine soudanien au Bénin de 1995 à 2015
Authors: AHONONGA Fiacre Codjo , GOUWAKINNOU Gérard Nounagnon , BIAOU Samadori Sorotori Honoré , BIAOU Séverin 
Published: February 2021

Le Nord du Bénin abrite 92,5 % de la couverture forestière nationale, principalement constituée des réserves de faune et de forêts classées, destinées à la conservation de la biodiversité. Ces zones du domaine classé, pourtant dotées pour la plupart de plans d’aménagement et d’un système de surveillance qui devraient limiter la dégradation du milieu, sont soumises à un fort taux de régression de la couverture forestière, dû aux pressions anthropiques. Cette étude vise à analyser la vulnérabilité des formations forestières dans les domaines classé et non classé de trois communes du Nord-Bénin : Matéri, Toucountouna et Ségbana. Une interprétation visuelle des images SPOT de 1995, 2005 et 2015, avec le logiciel Quantum GIS, a été effectuée pour faire ressortir les changements et évaluer la vulnérabilité des formations forestières. Les résultats révèlent une régression des formations forestières naturelles au profit de celles anthropiques. Les champs et jachères ont vu leur superficie multipliée par près de cinq entre 2005 et 2015. Au cours de cette même période, la dégradation a été plus forte dans le domaine classé que dans le non classé, alors qu’à l’inverse la déforestation a surtout affecté le domaine non classé. Les formations naturelles ont été vulnérables à la perte de superficie au profit des champs et jachères et des habitations. Les taux de vulnérabilité des différentes formations sont fonction de la période et du niveau de protection. Ces situations constituent une menace pour la biodiversité et nécessitent la mise en place d’une politique de planification de l’occupation des terres dans la périphérie du domaine classé. Cela garantira leur fonction et réduira les effets des facteurs de déforestation et de dégradation sur les réserves forestières.
Epidemiological Situation on COVID-19 in Irkutsk Region and Forecast for its Spread
Authors: Balakhonov S. V. , Chesnokova M. V. , Perezhogin A. N. , Nikitin A. Ya. , Kaverzina S. V. , Breneva N. V. , Dugarzhapova Z. F. , Savinykh D. F. , Potalitsina N. E. , Gavrilova T. A. , Likhanova N. A. , Chumachenko I. G. , Khakimova M. I. 
Published: February 2021

Assessment of a particular territory by its epidemiological significance is very relevant in the light of widespread occurrence of new coronavirus infection, COVID-19, in the Russian Federation.Objective. Detection of the epidemiological features and revealing trends in the epidemic process of new coronavirus infection in the Irkutsk Region and forecasting of its spread.Materials and methods. An operational analysis of the epidemiological situation on COVID-19 in the Irkutsk Region as of August 16, 2020 was performed. Restrictive measures were substantiated based on the calculation of the infection spread rate (Rt).Results and discussion. Irkutsk Region remained one of the adverse territories as regards human COVID-19 incidence in the Siberian Federal District and the Russian Federation as of August 16, 2020. The gradual dynamics of the epidemic process was revealed: at the first stage of the epidemic development it was facilitated by the imported cases from affected countries and regions of the Russian Federation, and subsequently by local transmission. The incidence increase was registered 2 months later than in central regions of the Russian Federation. Currently there is a consistent downward trend. The increase in the cases prevailed among rotation workers staying for shift and seasonal activities in the administrative center and northern districts of the Irkutsk Region. The epidemic pattern was determined by gender, age and social characteristics. It is demonstrated that the risk of the new coronavirus infection is determined by the intensity of contacts in family foci, the spread of infection in medical organizations and a significant proportion of asymptomatic carriers. High lethality rates (0.7 %) and mortality rates (31.1 o / oooo) were established among persons over 65 years. The stationary time series observed since June for changing the Rt-indicator with fluctuations ranging from 0.92 to 1.01 requires maintaining control of restrictive measures with prompt management decisions making based on the evolving epidemiological situation in the Irkutsk Region and taking into account the assessment of its possible complication risks.
Obtaining Recombinant Antigens for the Development of Serological Diagnosis of Marburg Fever
Authors: Volkova N. V. , Ivanova A. V. , Isaeva A. A. , Polezhaeva O. A. , Zaykovskaya A. V. , Shcherbakov D. N. , Kazachinskaya E. I. 
Published: February 2021

Aim. Production of recombinant viral antigens of the main immunodominant proteins: glycoprotein (GPΔMLD), nucleoprotein (NP) and matrix protein (VP40) of the Marburg virus, as well as the study of their antigenic and immunogenic properties.Materials and methods. To create recombinant proteins GPΔMLD, NP and VP40 of the Marburg virus, synthesized nucleotide sequences encoding these proteins cloned into the pET21a expression vector were used. The immunogenic and antigenic properties of the obtained recombinant proteins were tested using a number of biomodels (mice, chickens, and guinea pigs).Results and discussion. Recombinant plasmids containing genes encoding proteins GPΔMLD, NP, VP40 of the Marburg virus, as well as Escherichia coli producing strains, with the yield of purified preparations of recombinant proteins GPΔMLD, NP, VP40 from one liter of culture fluid – 5, 10, and 10 μg were obtained, respectively. When mice are immunized, recombinant proteins GP, NP, and VP40 MARV induce the synthesis of high titer antibodies (recombinant proteins NP and VP40 – more than 409600, and recombinant protein GPΔMLD – 12800). Mouse antibodies specific to recombinant proteins interact in an enzyme-linked immunosorbent assay (ELISA) with the antigen of inactivated MARV. Antibodies of chickens immunized with virus-like particles containing the surface glycoprotein of the Marburg virus and antibodies of guinea pigs immunized with an experimental DNA vaccine containing the GPΔMLD MARV gene recognize the recombinant GPΔMLD protein and the viral protein in the inactivated MARV. The resulting recombinant proteins are immunogenic/antigenic and can be used for the development of enzymelinked immunosorbent assay systems.