bluuebunny/crossref_metadata_2025_split huggingface dataset:
Preparation and characterization of ϐlurbiprofen capsules prepared by using liquisolid technique
Authors: Madhavi K  , Neelesh M  
Published: April 2021

The current project is mainly focussed on the application of liquisolid (LS) technique in the enhancement of dissolution profile of flurbiprofen. Flurbiprofen is a NSAID indicated for acute and chronic osteoarthritis, rheumatoid arthritis and spondylitis. It is selected as model drug as it is a BCS Class II drug and has very poor aqueous solubility of 10.45 ± 3.2μg/ml. Hence, this study was designed to improve the dissolution rate of flurbiprofen using LS technique. Initially, saturation solubility studies were performed to select liquid vehicle showing higher solubility of drug to obtain liquid medication. PEG 600 was selected as non-volatile solvent, used at three different drug concentrations of 33.33, 40 and 50 % w/w to form LS formulations. Further, they were converted to powder by means of Avicel PH 102 and Aerosil 200 as carrier and coating materials to prepare LS formulations. Rheological tests were performed for the LS powder systems to study the flow properties. Later, several LS formulations were prepared, encapsulated in hard gelatin capsules. These capsules containing LS systems were subjected to evaluation tests and in vitro drug release studies. The results of dissolution profile of formulation CF3 showed maximum release of 98% within 30 minutes which was two folds higher than that of conventional capsule. FTIR studies revealed no drug-excipient interaction. DSC, SEM and PXRD studies revealed that drug in the system was completely soluble and available in molecularly dispersed state. Finally, it can be concluded that LS technique proved to enhance the dissolution profile of Flurbiprofen.
Quality of life of mild cognitive impairment patients with type 2 diabetes mellitus and hypertension
Authors: Sreejith K  , Malarkodi Velraj  
Published: April 2021

Mild cognitive impairment (MCI) is a progressive neurodegenerative disease on which diabetes mellitus and hypertension play an important role as major risk factors. This study aims to assess the quality of life of MCI patients with type 2 diabetes and hypertension. A cross sectional study was carried out in a tertiary care teaching hospital. Cognitive status of patients were assessed by Addenbrooke’s Cognitive Examination III (ACE-III) and Montreal Cognitive Assessment (MoCA). Mild Cognitive Impairment Questionnaire (MCQ) was used to score the quality of life. SPSS 21.0 was used to perform statistical analysis. Kruskal-Wallis test and Mann Whitney U test were used to analyze the relationship between quality of life and demographic parameters. Totally 1887 patients with type 2 DM and hypertension were screened to detect MCI patients. The prevalence of MCI in the population was found to 24.64%. Mean age of the population was 45.12 ± 10.54. Quality of life of patients was affected due to MCI with diabetes and hypertension in early ages. Patients employed in Govt or private sector (p=0.021) and disease duration less than 10 years (p=0.025) had significantly better quality of life. Two domains of MCQ, such as emotional concern and practical concern were assessed separately found that MCI patient’s practical concern scores did not differ significantly from emotional concern scores (p= 0.874). Quality of life was affected in MCI patients with diabetes and hypertension in early ages. Routine clinical examination should consider the quality of life as an important parameter during the patient visit and necessary modifications should be given to enhance the quality of life as well as patient satisfaction.
Pelatihan Pembuatan Lilin Aromaterapi sebagai Tambahan Keterampilan Andikpas di LPKA Kelas II Bandung
Authors: Nining Nining , Yeni Yeni 
Published: April 2021

LPKA Kelas II Bandung merupakan lembaga pendidikan bagi anak yang berkonflik dengan hukum di daerah Provinsi Jawa Barat. Berbagai upaya pembinaan dilakukan LPKA berkerjasama dengan berbagai pihak salah satunya adalah Perguruan Tinggi sebagai tenaga pengajar kegiatan non-formal. Kegiatan pelatihan pembuatan lilin aromaterapi ditujukan untuk menambah keterampilan para peserta anak didik pemasyarakatan (andikpas) sebagai bekal keterampilan individu sehingga dapat digunakan kelak setelah kembali ke lingkungan masyarakat. Kegiatan diawali dengan trial pembuatan produk di laboratorium sebelum pelaksanaan pelatihan. Pelatihan disampaikan dalam bentuk presentasi dan dilanjutkan dengan praktik pembuatan lilin aromaterapi secara eksperimentatif dalam berbagai variasi bentuk. Produk berupa lilin aromaterapi yang berfungsi ganda, yaitu sebagai alat penerangan, media terapi dan penyegar ruangan. Kegiatan pelatihan membuat suatu produk yang memiliki nilai ekonomis tinggi melalui pembuatan lilin aromaterapi berbasis soy wax dalam wadah gelas dapat memiliki nilai jual yang tinggi. Hasil pengabdian menunjukkan bahwa kegiatan pelatihan mampu memotivasi peserta andikpas untuk berwirausaha dan peserta antusias mengikuti selama kegiatan pelatihan berlangsung.
Pencegahan Covid-19 Melalui Pemberian Asuhan Keperawatan Komunitas Daring
Authors: Sinaga Mei Rianita Elfrida 
Published: April 2021

Meluasnya penyebaran Corona Virus Disease (COVID-19) di Indonesia mengakibatkan berbagai upaya pencegahan dilakukan. Fokus upaya pencegahan adalah untuk memutus mata rantai penyebaran virus COVID-19. Salah satu cara efektif yang dapat dilakukan melalui penerapan Perilaku Hidup Bersih dan Sehat (PHBS). Untuk meningkatkan PHBS di masyarakat sebagai upaya pencegahan COVID-19, diperlukan pemberian asuhan keperawatan komunitas secara daring. Tujuan kegiatan pengabdian kepada masyarakat ini adalah untuk merubah perilaku dan meningkatkan pengetahuan terkait perilaku hidup bersih dan sehat sebagai upaya pencegahan COVID-19. Metode yang digunakan adalah partnership, proses kelompok, dan edukasi online. Kegiatan ini dilakukan melalui tiga tahapan yaitu persiapan, pelaksanaan asuhan keperawatan komunitas, dan evaluasi asuhan keperawatan komunitas. Hasil yang dicapai selama enam minggu dari kegiatan ini adalah meningkatnya pengetahuan masyarakat terkait perilaku hidup bersih dan sehat di RW 04 RT 18 Ledok Code Kotabaru, dan adanya perubahan perilaku di masyarakat melalui pemberian asuhan keperawatan komunitas secara daring. Pelaksanaan kegiatan ini mengalami beberapa kendala sehingga direkomendasikan peran tokoh masyarakat untuk menjamin keberlangsungan perubahan PHBS di masyarakat.
Pengaruh Model Pembelajaran Think Pair Share (TPS) Terhadap Prestasi Belajar Matematika Siswa
Authors: Meinalufi Yuyun , Supandi Supandi , Harun Lukman 
Published: April 2021

Penelitian ini merupakan penelitian eksperimen yang bertujuan untuk menganalisis pengaruh model pembelajaran Think Pair Share (TPS) terhadap prestasi belajar matematika siswa kelas VIII. Penelitian ini adalah penelitian Quasi Experimental Design dengan Nonequivalent Control Group Design. Populasi dalam penelitian ini adalah seluruh siswa kelas VIII SMP Ma’had Islam Semarang tahun 2020/2021. Melalui simple random sampling terpilih sampel yaitu kelas VIII B sebagai kelas eksperimen dan kelas VIII A sebagai kelas kontrol. Hasil penelitian menunjukkan: (1) Pembelajaran menggunakan model Think Pair Share (TPS) berpengaruh terhadap prestasi belajar matematika siswa, (2) Ketuntasan belajar siswa yang mendapatkan pembelajaran menggunakan model pembelajaran Think Pair Share (TPS) lebih tinggi daripada siswa yang mendapatkan pembelajaran menggunakan model pembelajaran konvensional, (3) Prestasi belajar matematika siswa yang mendapatkan pembelajaran menggunakan model pembelajaran Think Pair Share (TPS) lebih baik daripada siswa yang mendapatkan pembelajaran menggunakan model pembelajaran konvensional, (4) Pengaruh model pembelajaran Think Pair Share (TPS) adalah sebesar 35,5%, sedangkan sisanya dipengaruhi oleh variabel yang lain, (5) Ketuntasan belajar siswa yang mendapatkan model Think Pair Share (TPS) dengan pendekatan M-APOS lebih dari 85%, (6) Pembelajaran menggunakan model Think Pair Share (TPS) mampu meningkatkan prestasi belajar matematika siswa.
Efektivitas Model Pembelajaran Kooperatif Tipe Think Talk Write (TTW) dan Think Pair Share (TPS) Terhadap Kemampuan Berpikir Kreatif Siswa Berbantu Question Card
Authors: Indriyani Nida Naufi , Prasetyowati Dina , Supandi Supandi 
Published: April 2021

Tujuan penelitian ini adalah untuk mengetahui efektivitas model pembelajaran Think Talk Write (TTW) dan Think Pair Share (TPS) terhadap kemampuan berpikir kreatif siswa berbantu Question Card. Teknik pengambilan sampel menggunakan cluster random sampling diperoleh tiga kelas yaitu VIIC sebagai kelas eksperimen I, VIIB sebagai kelas eksperimen II dan VIIA sebagai kelas kontrol. Teknik mengumpulan data menggunakan metode observasi, tes dan dokumentasi. Hasil penelitian menunjukkan (1) terdapat perbedaan kemampuan berpikir kreatif siswa yang mendapatkan model pembelajaran Think Talk Write (TTW) berbantu Question Card, Think Pair Share (TPS) berbantu Question Card dan kelas konvensional; (2) kemampuan berpikir kreatif siswa yang mendapatkan model pembelajaran Think Talk Write (TTW) berbantu Question Card lebih baik dari kelas yang mendapatkan model pembelajaran konvensional; (3) kemampuan berpikir kreatif siswa yang mendapatkan model pembelajaran Think Pair Share (TPS) berbantu Question Card lebih baik dari kelas yang mendapatkan model pembelajaran konvensional; (4) kemampuan berpikir kreatif siswa yang mendapatkan model pembelajaran Think Talk Write (TTW) berbantu Question Card lebih baik dari pada model pembelajaran Think Pair Share (TPS) berbantu Question Card; (5) kemampuan berpikir kreatif siswa menggunakan model pembelajaran Think Talk Write (TTW) dan Think Pair Share (TPS) berbantu Question Card mencapai ketuntasan secara individu maupun klasikal; (6) terdapat pengaruh keaktifan siswa dalam pembelajaran Think Talk Write (TTW) dan Think Pair Share (TPS) berbantu Question Card terhadap nilai kemampuan berpikir kreatif siswa.
Proses Berpikir Siswa Smk Dalam Memecahkan Masalah Matematika ditinjau Dari Gaya Kognitif Field Independent dan Field Dependent
Authors: Janah Siti Nur , Rasiman Rasiman , Handayanto Agung 
Published: April 2021

Perbedaan proses berpikir siswa dalam memecahkan masalah matematika, yaitu terkait dengan penerapan konsep dalam memecahkan masalah matematika. Gaya kognitif dibagi menjadi dua yaitu gaya kognitif field independent (FI) dan field dependent (FD). Penelitian ini dilakukan dengan tujuan untuk mendeskripsikan proses berpikir siswa SMK dalam memecahkan masalah matamatika ditinjau dari gaya kognitif field independent dan field dependent. Penelitian ini merupakan jenis penelitian deskriptif kualitatif dengan subjek penelitiannya yaitu siswa kelas IX TKJ 3 SMK Syafi’i Akrom Pekalongan yang terdiri dari 2 siswa, satu siswa dengan gaya kognitif field independent dan satu siswa dengan gaya kognitif field dependent. Teknik pengumpulan data yang digunakan adalah tes GEFT untuk menentukan subjek, tes pemecahan masalah untuk mengukur proses berpikir dalam memecahkan masalah matematika dan wawancara merupakan kegiatan tanya jawab untuk mencapai tujuan penelitian. Teknik analisis data dilakukan dengan reduksi data, penyajian data dan penarikan kesimpulan. Teknik pemeriksaan keabsahan data peneliti menggunakan triangulasi metode. Hasil penelitian ini adalah siswa dengan gaya kognitif field independent memenuhi semua indikatoranatara lain dalam tahap memahami masalah, tahap melaksanakan rencana penyelesaian dan tahap mengecek kembali melakukan proses asimilasii sedangkan untuk tahap merencankan penyelesaian masalah menggunakan proses asimilasi dan akomodasi. Sedangkan siswa dengan gaya kognitif field dependent dalam tahap memahami masalah melakukan proses asimilasi, tahap rencana penyelesaian melakukan proses akomodasi, tahap melaksanakan rencana penyelesaian melakukan proses asimilasi dan tahap melihat kembali tidak melakukan proses asimilasi dan akomodasi.
Мeson resonances in the relativistic quark model
Authors: Sergeenko М. N. 
Published: April 2021

In this paper, the relativistic quark model is developed for the study of mesons and resonances as quasi-bound quark states. A classic analogue of the spinless Salpeter equation is analyzed. It is shown that the potential for a conservative isolated two-particle system is the Lorentz-scalar function of the distance between quarks and can be included into the particle mass, which leads to the position-dependent quark mass. The funnel-type potential is modified with taking into account the dependence of the strong coupling αS on the distance. The concept of free motion of particles in a bound state is developed. The eigenvalue problem for the bound state is defined by the relativistic quasiclassical wave equation for the scalar potential. Two exact asymptotic solutions of the equation for the Coulomb and linear parts of the potential are obtained analytically; on this basis, the complex-mass formula for mesons and resonances is written. The efficiency of the model is demonstrated by comparison of the calculation results with the data for the masses of ρ and D mesons.
Radiation instability of a relativistic electron beam moving in a split resonator
Authors: Anishchenko S. V. , Baryshevsky V. G. , Maroz I. V. , Rouba А. А. 
Published: April 2021

In this paper, we considered the radiation instability in a split asymmetric resonator for the relativistic case assuming the space charge of the beam. In the small-signal approximation, expressions for the energy loss by a particle passing through the resonator and for the beam current modulation are obtained. Based on analytical and numerical calculations, it is shown that the symmetric configuration provides the highest growth rate of instability. It is found that with the increase of the initial electron energy, the modulation of the beam current as well as the efficiency of the energy transfer from particles to the electromagnetic field decrease. The increase of the beam density has a positive effect on the radiation instability. The results obtained have to be taken into account when developing generators of electromagnetic radiation or a system for modulating the beam current based on a split resonator.
Evaluation of Acute and Subacute Toxicity of Two Different Extracts from Que Zui Tea in Rats
Authors: Wang Yongpeng , Njateng Guy Sedar Singor , Zhao Tianrui , Yang Meilian , Wang Yifen , Cao Jianxin , Liu Yaping , Cheng Guiguang 
Published: April 2021

The buds of Vaccinium dunalianum Wight (VD) are widely used in Yunnan as herbal tea [Que Zui Tea (QT)] and herb. However, the security and toxicity of QT have not been determined yet. The aim of this study is to evaluate the acute and subacute‐toxicity of hot water (QTW) and aqueous‐ethanol (QTE) extracts of QT. Acute‐toxicity studies of QTW and QTE revealed no signs of related to treatment, indicating that median‐lethal‐dose (LD50) values of QTW and QTE is surpass 5000 mg/kg. The results of subacute‐toxicity studies of QTW and QTE showed no significant side reaction of all doses the two extracts. The levels of Lymphocyte (LYM) and percentage of lymphocytes (LYM%) significantly decreased, and percentage of granulocytes (GRA%) increased in rats that received these two extracts at doses greater than 1250 mg/kg/day. However, the 1250 and 2500 mg/kg/day QTW and QTE did not trigger any pathological changes in body weight or organ tissue, so partial changes in blood parameters were considered as minor symptoms. Therefore, the present results demonstrated that the two extracts are safe at 2500 mg/kg/day or at lower doses.
PENERAPAN METODE DEMONSTRASI UNTUK MENINGKATKAN KEMAMPUAN GURU DALAM MENGGUNAKAN MICROSOFT OFFICE POWER POINT SEBAGAI MEDIA PEMBELAJARAN DI SMPN 1 SUKORAME LAMONGAN SEMESTER GANJIL TAHUN PELAJARAN 2019/2020
Authors: Sulkan Sulkan 
Published: April 2021

Proses pembelajaran yang dilaksanakan di SMPN 1 Sukorame Lamongan dinilai masih belum memanfaatkan teknologi yang disediakan sekolah untuk menunjang pendidikan, terutama dalam mata pelajaran tertentu. Hal ini disebabkan para guru mata pelajaran masih belum mengerti seluk beluk media pembelajaran yang akan dimanfaatkan. Untuk meningkatkan kualitas pendidikan di SMPN 1 Sukorame Lamongan diperlukan sebuah pelatihan untuk membantu meningkatkan kemampuan guru di SMPN 1 Sukorame Lamongan khususnya dalam aspek pengajaran. Penerapan metode Demonstrasi dimulai dengan peneliti menjelaskan materi menggunakan media Microsoft Office Power Point sebagai media demonstrasi dan memperagakannya. Kemudian, peserta membentuk kelompok untuk berdiskusi mengerjakan tugas. Setelah tugas selesai, kelompok mendemonstrasikan tugas yang telah diberikan. Keberhasilan peningkatan kemampuan peserta penelitian pada penelitian ini adalah seluruhpeserta mendapatkan nilai tugas membuat slide presentasi dengan 75% peserta pelatihan tuntas KKM dengan nilai Baik atau Sangat Baik. Pada siklus I terdapat 50% peserta yang sesuai dengan indikator keberhasilan. Pada siklus II 100 % atau seluruh peserta sesuai dengan indikator keberhasilan. Dengan demikian, metode demonstrasi mampu meningkatkan kemampuan peserta dalam menggunakan Microsoft Office Power Point sebagai media pembelajaran di SMPN 1 Sukorame Lamongan tahun pelajaran 2019/2020.
VIRULENCE OF THE NORTH CAUCASIAN POPULATION OF PUCCINIA GRAMINIS PERS. F. SP. TRITICI
Authors: Volkova G. V. , Gladkova Е. V. , Miroshnichenko O. O. 
Published: April 2021

The aim of the study was to monitor the virulence of Puccinia graminis Pers. f. sp. tritici in the North Caucasus. The objectives of the study were to collect P. graminis infectious material from sown winter wheat varieties and evaluate the long-term dynamics of the pathogen virulence in the North Caucasus region in 2014-2019. As a result, an analysis of the virulence of the stem rust pathogen population of wheat collected in Krasnodar, Stavropol Territories, and Rostov Region was carried out. 81 mono-empty mushroom isolates were isolated and differentiated. The genes Sr5, Sr31, Sr38 were characterized by high efficiency. On the lines with the genes Sr7b, Sr8b, Sr9f, Sr9g, Sr10, Sr11, Sr12, Sr13, Sr14, Sr21, Sr22, Sr23, Sr26, Sr29, Sr32, Sr33, S35, Sr37, SrDp2, SrWLD, a variation in the virulence frequencies of P. graminis was observed. Significant changes (in the direction of increasing occurrence) in the North Caucasian population 2014-2019 the pathogen was noted in the frequency of clones virulent to wheat lines with resistance genes Sr11, Sr21, Sr22, Sr26, Sr32, Sr33. A decrease in the frequency of clones virulent to Sr8b, Sr9g, Sr10, Sr12, Sr14, Sr35. At approximately the same level, the occurrence of clones virulent to the genes Sr6, Sr7a, Sr8а, Sr9a, Sr9b, Sr9d, Sr9e, Sr13, Sr15, Sr16, Sr17, Sr19, Sr20, Sr24, Sr25, Sr27, Sr30, Sr36, Sr39, Sr40, Sr44, SrGt, SrTmp. Effective genes that have shown their resistance to P. graminis in the seedling phase are proposed for use in breeding in southern Russia to create new varieties of wheat.
RECOVERY PROSPECTS FOR THE RUSSIAN FEDERATION RECLAMATION COMPLEX
Authors: Dubenok N. N. , Olgarenko G. V. 
Published: April 2021

The article reveals a real situation in the Russian Land Reclamation Complex, and the using of developed areas; there are presented the causes of insufficient using efficiency of the developed lands. The main goal of land reclamation developing is formulated; it is its renovation according to modern engineering and technical level, of available land reclamation and hydro-economic fund of Russian Federation. There are developed the main measures aimed to the rehabilitation of technical and economic and technological potential of land reclamation systems, ensuring proper functioning of the land reclamation and hydro-economic complex, as well as the using for agricultural production no less than 90% of available developed lands; that is the most rational way for getting of ecologic and economic balanced productivity of developed lands and a base for the country’s future stable land reclamation complex development. Under global political and economic competition conditions and economic crisis development and the raising of social and economic issues, land reclamation complex development is possible only after working out of the State Program on rehabilitation and development of land reclamation complex of Russian Federation in 2021-2020, keeping in mind the regional specific conditions of farming development, technical condition and level of land reclamation systems, real use and ecologic condition of developed lands.
Pengembangan Bahan Ajar Matematika Berbasis Problem Based Learning Pada Siswa Sekolah Dasar
Authors: Lestari Fida , Egok Asep Sukenda , Febriandi Riduan 
Published: April 2021

This study aims to develop teaching materials based on Mathematics Based Problem-Based Learning in fifth grade students of SD 37 Lubuklinggau in accordance with the 2013 curriculum and to produce valid and practical teaching materials for use in learning. This research is a development study with a development model adapted from the Four-D model. Based on the results of the analysis Based on the experts, namely: linguists, material experts, and media experts determine statistical teaching materials based on problem-based learning criteria meet the criteria with an average score of 0.76. Based on the analysis of teacher and student worksheets consisting of 9 people obtained from problem-based learning based statistical teaching materials meet the requirements with an average score of 95%, so that learning materials can be improved based on statistical problems Problem Based Learning requires valid, practical criteria and can be used in learning.
Keywords: Development, Mathematic Teaching Materials, Problem Based Learning
Pengaruh Disiplin Belajar terhadap Hasil Belajar Bahasa Indonesia di Sekolah Dasar
Authors: Handayani Eka Selvi , Subakti Hani 
Published: April 2021

Disiplin belajar sangat berpengaruh terhadap hasil belajar siswa. Salah satu faktor yang memengaruhi hasil belajar adalah disiplin belajar. Penelitian ini terfokus pada disiplin belajar terhadap hasil belajar bahasa Indonesia siswa kelas III SD Negeri 002 Sungai Pinang, karena bahasa Indonesia merupakan ilmu yang pasti. Sehingga siswa cenderung tidak menyukai mata pelajaran bahasa Indonesia dan hal ini dapat memengaruhi hasil belajar siswa. Penelitian ini merupakan penelitian ex post facto, karena tidak ada kontrol terhadap variabel bebas dan peneliti tidak mengadakan pengaturan atau manipulasi terhadap variabel bebas. Pada penelitian ini terdiri atas dua variabel, yaitu satu variabel bebas dan satu variabel terikat. Variabel bebas dalam penelitian ini adalah disiplin belajar (X). Sedangkan variabel terikatnya adalah hasil belajar bahasa Indonesia (Y). Untuk pengambilan sampel menggunakan teknik sampling jenuh. Berdasarkan hasil penelitian dan hasil analisis dapat diketahui dari hasil perhitungan uji hipotesis diperoleh thitung = 9,906 untuk variabel (X) dan (Y). Kemudian mencari ttabel dengan α = 5%, dk = 33 - 2 = 31, sehingga ttabel sebesar 1,696. Karena thitung > ttabel maka H diterima, jika diterima maka terdapat pengaruh disiplin belajar terhadap hasil belajar bahasa Indonesia siswa kelas III SD Negeri 002 Sungai Pinang Kota Samarinda.
Kata Kunci: Disiplin belajar, hasil belajar, bahasa Indonesia