bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Comparative Study of Oral Health Status of Outpatients with Mental Disorders and Healthy Controls in a Nigerian Tertiary Hospital
Authors: Amedari McKing Izeiza , Akinsulore Adesanmi , Ogunbodede Eyitope O , Jeboda Sonny O 
Published: July 2021

Objective:
The objective of this study was to determine and compare the oral health status of outpatients with mental disorders (OPMDs) and healthy controls (HCs) in a Nigerian tertiary hospital.

Methodology:
A comparative cross-sectional study among 140 OPMDs was consecutively recruited from the Mental Health Clinic of a Nigerian tertiary teaching hospital. Furthermore, 140 age- and sex-matched HCs screened using the 12-item General Health Questionnaire were recruited from the general outpatient clinic. Oral health status was assessed using the Decayed, Missing, and Filled Teeth (DMFT) index, the community periodontal index modified (CPI modified), the Oral Hygiene Index-Simplified (OHI-S), and the gingival index (GI). Bivariate analyses were carried out to make comparisons between the two groups, and the level of significance was set atP< 0.05.

Results:
A total of 280 participants were recruited. This comprised 68 male participants and 72 female participants in each group. The mean DMFT in the OPMD group was 0.50 (±1.09) and 0.17 (0.645) for the HC group. The prevalence of dental caries was 24.3% in the OPMD group and 10% in the HC group. The mean OHI-S score was 2.68 (±0.97) and 2.38 (±0.98) and GI score was 1.09 (±0.46) and 0.87 (±0.87), while clinical attachment loss was seen in 48.5% and 32.8% for the OPMD and HC groups, respectively.

Conclusion:
The prevalence of common oral diseases in OPMD was higher compared to HC, thus the study provides evidence on the poor oral health of OPMD. Furthermore, there is a need to incorporate preventive dental education into the management of OPMD.
Characteristics of Three Person-to-Person Transmission Clusters of Severe Fever with Thrombocytopenia Syndrome in Southeastern China
Authors: Tao Mingyong , Liu Ying , Ling Feng , Zhang Rong , Shi Xuguang , Ren Jiangping , Guo Song , Sun Jimin , Jiang Jianmin 
Published: July 2021

ABSTRACT.
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease worldwide. It can be transmitted from person to person, and the fatality rate is very high. During this study, three SFTS clusters including 12 associated cases were identified in three counties in Zhejiang Province from 2018 to 2020. The median age of the three index patients was 70 years, and that of secondary case patients was 59 years. Of note, the mortality rate of the index patients was 100%. The mortality rate of secondary case patients was 11%. The total secondary attack rate (SAR) was 30% (9/30). The SARs of cluster A, cluster B, and cluster C were 38% (3/8), 21% (3/14), and 38% (3/8), respectively. Additionally, the interval from onset to diagnosis was 4 days. The intervals from disease onset to confirmation of the index cases and secondary cases were 7 days and 4 days, respectively. All secondary case patients had a history of close contact with blood or body fluids of the index patients. These results indicate that SFTS patients should not be discharged until recovery. When SFTS patients die, the corpses should be transferred directly from the hospital to the crematorium for cremation by persons wearing proper protective equipment to prevent virus transmission.
Necati Cumalı’nın Makedonya 1900 Adlı Eserinde Kültürel Bellek İnşası
Authors: SOYSAL EŞİTTİ Asli 
Published: July 2021

Necati Cumalı’nın yazın dünyasında Balkanlar önemli bir yere sahiptir. 1921 Florina doğumlu olan yazar, geçmişi ve ait olduğu kökleri bu coğrafya aracılığıyla tanımlar. Yazarın biyografik yaşam öyküsü ile iç içe geçen Makedonya 1900’de yer alan öykülerde, Balkanlardaki faklı milletlerin uluslaşma süreçleri sonucu yaşanan çatışmalar ve ayrışmalar anlatılır. Yüzyıllar boyunca hâkim olduğu Balkanlarda Osmanlı İmparatorluğu’nun gücünün sona ermesiyle birlikte Balkanları vatan bilen Türklerin farklı milletler tarafından gördüğü baskıya ve uğradığı zulme hikâyelerde yer verilmiştir. Balkanlarda yaşanan toprak kayıplarının neticesinde bu coğrafyada yaşayan Türkler dünyaya geldikleri ve vatanları bildikleri Balkanlara veda etmek zorunda kalmışlardır.
Kültürel bellek, tarihe şahitlik edenler tarafından tarihin yazılmasıdır. Yüzlerce yıl Balkan topraklarını vatanı bilen Türklerin kültürel belleğinde Balkanlar kurucu bir öneme sahiptir. Çalışmada Makedonya 1900 adlı eserde yer alan hikâyeler incelenerek, kültürel bellek inşasının yansımaları ortaya konulmuştur. Çalışmada, kültürel bellek inşasının, Balkanların kültürel bellek mekânı olarak insanların hafızalarında tuttuğu yer ve Balkanlarda farklı milletlerin kendilerine ait devletler kurma sürecinde yaşanan çatışmaların ve köy basma, tecavüz, öldürme, göç gibi olayların kültürel belleğe yansımaları ele alınmıştır.
First Records of Freshwater Sponges (Porifera: Spongillidae) for Great Smoky Mountains National Park
Authors: Copeland John E. , Kunigelis Stan C. , Stuart Emily A. , Hanson Kayleigh A. 
Published: July 2021

Abstract
A survey of four selected streams in the Tennessee portion of the Great Smoky Mountains National Park was conducted to document the presence of freshwater sponges. Streams were surveyed by wading and observing rock and log substrates for sponges. Sponges were viewed with a 10X magnifier for gemmules. If gemmules were present a portion of the sponge containing gemmules was collected. Scanning electron microscopy of gemmules and spicules was used for taxonomic identification. Two species, Radiospongilla crateriformis and Trochospongilla horrida, were discovered. Both were found in the Abrams Creek embayment of Chilhowee Lake. These findings represent the first records of freshwater sponges within the Great Smoky Mountains National Park.
The three-dimensional groundwater salinity distribution and fresh groundwater volumes in the Mekong Delta, Vietnam, inferred from geostatistical analyses
Authors: Gunnink Jan L. , Pham Hung Van , Oude Essink Gualbert H. P. , Bierkens Marc F. P. 
Published: July 2021

Abstract. Over the last decades, economic developments in the Vietnamese Mekong Delta
have led to a sharp increase in groundwater pumping for domestic,
agricultural and industrial use. This has resulted in alarming rates of land
subsidence and groundwater salinization. Effective groundwater management,
including strategies to work towards sustainable groundwater use, requires
knowledge about the current groundwater salinity distribution, in particular
the available volumes of fresh groundwater. At the moment, no comprehensive
dataset of the spatial distribution of fresh groundwater is available. To
create a 3D model of total dissolved solids (TDS), an existing geological
model of the spatial distribution and thickness of the aquifers and
aquitards is updated. Next, maps of drainable porosity for each aquifer are
interpolated based on the sedimentological description of the borehole data.
Measured TDS in groundwater, inferred TDS from resistivity measurements in
boreholes and soft incomplete data (derived from measurements in boreholes
and data from domestic wells) are combined in an indicator kriging routine
to obtain the full probability distribution of TDS for each (x,y,z)
location. This statistical distribution of TDS combined with drainable
porosity yields estimates of the volume of fresh groundwater (TDS < 1 g L−1) in each aquifer. Uncertainty estimates of these volumes follow from a
Monte Carlo analysis (sequential indicator simulation). Results yield an
estimated fresh groundwater volume for the Mekong Delta of 867 billion cubic metres with an uncertainty range of 830–900 billion cubic metres, which is
somewhat higher than previous assessments of fresh groundwater volumes. The
resulting dataset can for instance be used in groundwater flow and salt
transport modelling as well as aquifer storage and recovery projects to
support informed groundwater management decisions, e.g. to prevent further
salinization of the Mekong Delta groundwater system and land subsidence, and
is available at https://doi.org/10.5281/zenodo.4441776 (Gunnink
et al., 2021).
Slope deformation, reservoir variation and meteorological data at the Khoko landslide, Enguri hydroelectric basin (Georgia), during 2016–2019
Authors: Tibaldi Alessandro , Pasquaré Mariotto Federico , Oppizzi Paolo , Bonali Fabio Luca , Tsereteli Nino , Mebonia Levan , Chania Johni 
Published: July 2021

Abstract. The Greater Caucasus mountain belt is characterized by deep valleys, steep
slopes and frequent seismic activity, the combination of which results in
major landslide hazard. Along the eastern side of the Enguri water reservoir
lies the active Khoko landslide, whose head scarp zone affects the important
Jvari–Khaishi–Mestia road, one of the few connections with the interior of
the Greater Caucasus. Here, we present a database of measurement time series
taken over a period of 4 years (2016–2019) that enables us to compare slope
deformation with meteorological factors and human-induced perturbations owing
to variations in the water level of the reservoir. The monitoring system we
used is composed of two digital extensometers, placed within two artificial
trenches excavated across the landslide head scarp. The stations are
also equipped with internal and near-ground surface thermometers. The dataset is integrated by daily measurements of rainfall and lake level. The
monitoring system – the first installed in Georgia – was set up in the
framework of a NATO-funded project, aimed at assessing different types of
geohazards affecting the Enguri artificial reservoir and the related
hydroelectrical plant. Our results indicate that the Khoko landslide
displacements appear to be mainly controlled by variations in hydraulic
load, in turn induced by lake level oscillations. Rainfall variations might
also have contributed, though this is not always evident for all the studied
period. The full databases are freely available online at the following DOI:
https://doi.org/10.20366/unimib/unidata/SI384-2.0 (Tibaldi et al., 2020).
Kiel 1969: Ein quellenkritischer Blick auf Tradierungsprozesse als „Arbeit am Mythos“
Authors: Wardenga Ute 
Published: July 2021

Abstract. The contribution uses the example of the 1969 Congress of German Geographers in Kiel to illustrate how traditions are born and passed on in
German-speaking geography. By means of hermeneutic source criticism, it
investigates how the events of „Kiel 1969“ gave rise to a myth. It concludes that the congress's participants experienced „Kiel 1969“ as the site of an enormously dense social interaction within their science. Most importantly, participants' suggestive oral reports in the aftermath of the congress turned it into the „myth of Kiel“, which became an essential driving force of German-speaking geography's modernization.
Influence of combined transplantation of multipotent mesenchymal stromal cells and stellate liver cells on its morphofunctional state after partial hepatectomy
Authors: Maklakova I. Yu. , Grebnev D. Yu. , Osipenko A. V. 
Published: July 2021

The aimof the study was to study the changes in the morphofunctional state of the liver after the combined transplantation of multipotent mesenchymal stromal (MMSC) and stellate liver cells (ZCP) in animals with partial hepatectomy.Materials and methods.The MMSC culture was isolated from the placental chorion of 5 laboratory animals f female mice aged 3-4 months, weighing 22-23 g, gestation period of 18 days. The mononuclear fraction of the cells was obtained by sequential mechanical and enzymatic treatment of the placental tissue. The cultivation of MMSCs was carried out in a CO2 incubator at a temperature of 370C with a carbon dioxide content of 5% and a humidity of 90%. ZCP was isolated by collagenase-pronase perfusion of the liver, followed by cell separation in the histodense density gradient. MMSCs of the 3rd passage were introduced, and ZKP was introduced immediately after isolation. MMSCs at a dose of 4 million cells/kg and ZCP at a dose of 9 million cells/ kg were used for transplantation to labotory animals. The cells were injected 1 hour after partial hepatectomy. The biochemical parameters of peripheral blood and morphometric parameters of the liver were evaluated on the 3rd, 7th day after the administration of MMSC.Results.As a result of the study, it was found that the combined transplantation of MMSC and ZCP after partial hepatectomy leads to the restoration of the level of enzymes that characterize cytolysis and cholestasis, normalization of the protein-synthetic function of the liver, normalization morphometric parameters of the liver. A significant mechanism for restoring the morphofunctional state of the liver can be considered the influence of transplanted MMSCs and ZCP on the cell repair system, which leads to a decrease in the severity of programmed cell death of hepatocytes and the level of pathological mitoses.Discussion.Combined transplantation of MMSCs and HCP after partial hepatectomy leads to an increase in the level of hepatocyte growth factor (HGF), thus contributing to an se in the mitotic activity of hepatocytes and the restoration of liver mass. The transplanted cells also, by increasing the activity of DNA repair enzymes of the PARP family, lead to a decrease in the level of pathological mitoses, inhibition of their programmed cell death.Conclusions.The conducted studies demonstrate the ability of combined MMSC and PCR transplantation to restore the morphofunctional state of the liver after partial hepatectomy and provide the basis for conducting pilot clinical studies
Impact of some intraoperative factors on wound infection in cardiac surgery
Authors: Stepin A. V. 
Published: July 2021

Relevanc. Surgical Site Infection (SSI) after open heart surgery is a significant problem in clinical, social, and economic aspect which causes the need to identification of the preferred procedures for successful prevention of the SSI.Objectives. To determine risk of the SSI in cardiac surgery depending on complexity of intervention, using of cardiopulmonary bypass (CBP) and use of both internal mammary arteries (IMA).Methods. Prospective observations study from 2010 to 2019 in cardiac surgery department of the Ural Institute of Cardiology, where in total 4993 open heart surgery procedures were consecutively performed. All SSI cases were recorded up to 90 days after surgery. The analysis was performed to identify risk of cardiopulmonary bypass (CPB), bilateral IMA grafting and combined procedures on the risk of the postoperative wound infection.Results. During the investigation period, total 220 cases of the SSI (4,5%) have been registered of the 4993 patients undergoing open heart surgery. It included 42 cases of deep sternal infection (0,9%) and 178 cases of superficial infection (3,6%). The main pathogen identified was Staphylococcus epidermidis (56,4%). During the hospital period, 151 cases (66,5%) of SSI have been detected, with the median time to detection of the complication 6 days. The relative mortality risk in deep sternal infection group was 4,4 times higher than in the group without SSI (HR 4,6, 95 % CI 1,5-13,9, p=0,003624). CABG increases the relative risk of SSI in compare with non-CABG procedures (OR 3,086169; 95%CI 1,281 – 7,437), while the complexity of the operation (combined versus isolated interventions) does not significantly increase the risk (OR 0.972283; 95% CI: 0.696 - 1.359). The incidence of SSI in the group of in situ BIMA grafting was 8.8%, significantly increasing the likelihood of the SSI in compare to those with SIMA (OR 2.167983, 95% CI 1.463 - 3.212; p =0,000057). CBP significantly increases the risk of postoperative wound infections (OR 1.523890, 95% CI 1.149 - 2.022, p = 0.001742).Conclusions. Refusal of cardiopulmonary bypass, simultaneous procedures and bilateral coronary artery bypass does not allow completely to avoid postoperative wound infections. Nevertheless, the technical features of the preparations and use of grafts, including skeletonization, prevention of coagulation and the preference for sequential composite CABG, can reduce the risk associated with the type of the open heart surgery.
Analysis of the primary health care state for the rural population at the regional level
Authors: Moskvicheva M. G. , Polinov M. M. 
Published: July 2021

Introduction. The main goal of the state policy in the field of healthcare is to form a system that ensures the availability of medical care and increases the efficiency of medical services. The volume, type and quality of medical care must correspond to the level of morbidity, the needs of the population and the advanced achievements of medical science. Primary health care is the backbone of the health care delivery system. The problem of it improvement, including in rural areas, is a priority and has national significance. The development of measures to increase the availability of primary health care according to the territorial principle is an urgent scientific and practical problem.The purpose of the study — based on the analysis, methodologically substantiate and develop measures to increase the availability and improve the system of organizing the provision of primary health re to the rural population on a territorial basis.Materials and methods. Mathematical-statistical and analytical (quantitative, structural, comparative) research methods were used.Results and Discussion. In the Chelyabinsk Region, there are disproportions in the provision of the population with medical personnel: the provision of the urban population with doctors and l personnel is significantly higher than that of the rural population. The indicator of staffing with paramedical personnel in full-time positions of feldsher-obstetric stations is 20.1% lower than in the Russian Federation. The index of "combination rate" among doctors working in outpatient departments is 1.2 times higher than the target indicator of the National Health Project, and in rural areas it is 1.1 times. In order to unify the organizational and methodological approaches, the authors proposed a classification of medical stations and their organizational and functional structure.Conclusions. The organization of the provision of primary health care to the rural population according to the territorial-district principle with the formation of an organizational model of the rural medical district will increase the availability of primary medical health care to the rural population.
The analysis of high cardiovascular morbidity and mortality in the adult population as a medical and social problem and the search for ways to solve it
Authors: Kosolapov V. P. , Yarmonova M. V. 
Published: July 2021

Introduction.The article is devoted to the analysis of the state of cardiovascular morbidity (CVD), mortality of the population and the demographic situation, as well as determining the prevalence of CVD as a medical and social problem at the federal and regional levels. The analysis of the implementation of the policy of providing medical care to patients with CVD, modern scientific publications on the indicated problem, and the search for ways to solve the medical and social problem of high morbidity and mortality from CVD are carried out.Materials and methods.The data of official statistical information on the morbidity and mortality of the adult population of the Russian Federation and the Voronezh region for 2010–2019 were used, the works of modern domestic and foreign scientists dealing with the solution of this problem were studied.Results.It has been established that high CVD and mortality are an acute medical and social problem. Mortality from CVD in Russia in 2019 amount to 46.8% of the total number of deaths. The mortality rate from CVD in Russia exceeds that in the developed countries of the European Union. Despite the presence of positive trends in the fight against this disease, the mortality rate from CVD in the Voronezh region is higher than the average for the Russian Federation (601.8 and 573.2 per 100 thousand population, respectively). The deterioration of the demographic situation, the presence of active targeted projects in this area are the basis for conducting scientific research to find ways to duce CVD and mortality in the adult population.Conclusion.The high morbidity and mortality from CVD requires a search for new ways to solve the problem, since the existing approaches to its solution are not holistic and universal. It is urgent to develop an integrated approach that takes into account the medical and social characteristics of the adult population of the region.
Analysis of the effectiveness of aspirin for the prevention of preeclampsia and alternative methods of prevention
Authors: Kudryavceva E. V. , Kovalev V. V. , Bayazitova N. N. , Milyaeva N. M. , Kaumova A. V. 
Published: July 2021

Introduction. Preeclampsia is a hypertensive disorder of pregnancy that remains one of e leading causes of maternal and perinatal morbidity and mortality. The preventive strategy of prophylaxis with acetylsalicylic acid gives only a relative reduction in risk, and in a significant part of cases is ineffective. At the same time, the issue of preeclampsia prophylaxis is extremely relevant, since there are no effective methods for treating this condition, with the exception of the completion of gestation.Purpose of the study. Based on the scientific literature, to evaluate the effectiveness of aspirin in the prevention of preeclampsia and to determine the possible reasons for the lack of effectiveness of such prevention.Materials and methods. We conducted a search for scientific literature, as a result of which 39 sources were selected for the final scientific review (2010-2020). The PubMed, ResearchGate and Elibrary databases were used to search for scientific literature.Results and discussion. The article presents a literature review of the analysis of the effectiveness of aspirin for the prevention of preeclampsia over the past 5 years, describes the mechanism of action of aspirin, presents studies that confirm or refute the effectiveness of aspirin depending on the dosage and gestational age. Potential alternative agents for the prevention of preeclampsia in cases of aspirin ineffectiveness have been reviewed.Conclusion. Literature review data show that the effectiveness of aspirin for the prevention of preeclampsia depends on the chronobiological effect, compliance, gestational duration and dosage. It is necessary to continue research on the effectiveness of aspirin, and studies carried out on the Russian population will be of particular value for the Russian Federation.