bluuebunny/crossref_metadata_2025_split huggingface dataset:
KERAGAMAN SUDUT PERCABANGAN DAN PANJANG INTERNODUS TANAMAN UJI KETURUNAN PULAI GADING (Alstonia scholaris (L.). R.Br.)
Authors: Mashudi Mashudi 
Published: April 2021

Alstonia scholaris is a local species, widely used for making hadicraft and pencil slate. The purpose of this paper is to determine the effect of provenance and family on the diversity of tree branching angle and internodus length of A. scholaris plants. The experimental design used was a Completely Randomized Block Design with provenance and family treatments. The number of provenance involved was 5 provenances (Lombok, Jayapura, Solok, Timor and Bali) and the number of family involved was 48 families. Each family planted 4 seeds per plot with a spacing of 4 x 2 m and was repeated 3 times. The results of the analysis of variance showed that the provenance and family had a significant effect on the tree branching angle and length of the internodus. The average of tree branching angle between families ranges from 37.50 - 61.25o and the length of the internodus ranges from 1.15 - 2.20 cm. Provenance with the best tree branching angle are occupied by the Timor provenance and the best length of the internodus is occupied by the Lombok provenance. The best tree branching angle is occupied by 20 families with an angle range of 50.91o - 61.250 and the best length of the internodus is occupied by 22 families with a range of 1.82 - 2.20 m.
IMPLEMENTASI KEMITRAAN KEHUTANAN DI KESATUAN PENGELOLAAN HUTAN PRODUKSI WAY TERUSAN
Authors: Wandira Yuni Ayu , Kaskoyo Hari , Febryano Indra Gumay , Yuwono Slamet Budi 
Published: April 2021

One of the government policies to increase community participation in forest management is Forestry Partnership. The purpose of this study was to determines the process of forestry partnership implementation in KPHP Way Terusan. Data collection used in this research was interviews and then the data is analyzed descriptively. The results showed that the implementation process of forestry partnership was long enough and have a lot of challenges. The supporting factors in forestry partnership were the existence of high support done by the community towards forestry partnership programs, communities high trust to KPHP Way Terusan and high support by other related parties (stakeholders). Inhibit factors in forestry partnership were low capabilities of human resources, the problems within farmer groups organization, maintainless communications between government and farmer groups and low community participation.
KAJIAN KARAKTERISTIK BRIKET DARI PENCAMPURAN JERAMI DAN SEKAM PADI DARI LIMBAH PASCA PANEN DI LAHAN GAMBUT
Authors: Rianawati Fonny , Abidin Zainal , Naparin Muhammad 
Published: April 2021

This study aims to study the characteristics of briquettes from rice straw and rice husks in the form of moisture content, density, ash content, flight substance content, and heating value with different mixing variations in an effort to overcome the occurrence of deep forest / land fires to control forest or land fires in wetland areas by innovating and utilizing technology of straw and rice husks from post-harvest waste. The test results showed, the characteristic values are not much different for each mixing variation and are still below the Indonesian National Standard (SNI) No. 1-6235-2000, namely The heating value ranges from 2729.33 - 3492.14 cal/g (SNI ≥ 5000 cal/g), bonded carbon content ranges from 2.3524 -12.5870% (SNI ≥ 77%), ash content ranges from 27.3367 -29.8367% (SNI ≤ 8%) and the moisture content ranges from 18.2130 -28.8903% (SNI ≤ 8%). This is presumably due to the large content of the adhesive used, the pressing and drying processes that cause high water content, because high water content will cause a low calorific value. Low heating value will cause a large amount of ash content which causes a low value of bound carbon. However, overall charcoal briquettes from rice husks and rice straw can be applied to the community as a technological innovation that can be used in the use of post-harvest waste in an effort to control forest and land fires with land processing without burning.
KARBON TERSIMPAN DI TATA GUNA LAHAN SUB-SUB DAS KHILAU DAS SEKAMPUNG
Authors: Ningsih Ratih Rinda , Banuwa Irwan Sukri , - Duryat , Yuwono Slamet Budi 
Published: April 2021

The khilau is one of sub-watershed of the sekampung watershed. The area was very important due to its function as catchment area which is also located close to TAHURA (great forest park ) Wan Abdurrachman, there for sub-watershed khilau plays a very strategic role in the preservation of biodiversity and climate change. The study aims were to analyze the carbon determine the total carbon dioxide uptake and oxygen release in the khilau sub-watershed. The carbon stored was extimated by using allometric equation the biomass tree. The biomass expantion factor was employed estimated of biomass. The carbon conten multiplication with the value of the conversion of carbon elements to carbon dioxide, while for the oxigen release was estimated by multiplying the value of carbon squestration by the conversion value of carbon atoms to oxygen based on atomic weight. The result showed that carbon stored in the forest was 141,69 tons/ha, it was greater than agroforetry (75,33 tons/ha), shrubs (24,74 tons/ha), annual plant (11,13 tons/ha) and paddy fields (3,45 tons/ha) with a total area of forest 52,22 ha, agroforestry 457,86 ha, shrub 28,74 ha, annual plant 84,8 ha and paddy fields 2,36 ha. The total carbon dioxide absorbtion was 159.832,73 tons and oxygen release was 426.220,61 tons.
PEMETAAN JALUR INTERPRETASI EKOWISATA DI DESA PAHMUNGAN, KABUPATEN PESISIR BARAT
Authors: Akmal Rio Rahmad , Djoko W Gunardi , Santoso Trio 
Published: April 2021

Ecotourism usually has an educational value packed in the form of natural beauty and is in the countryside. Lampung has many potential ecotourism, one of which is located in West Coast district. This research was conducted in March 2019 to April 2019 in Pahmungan Village, central Coastal district, West Coast Regency, Lampung province. The Pekon or the village of Pahmungan has an area of 2,600 ha, Pekon Pahmungan is located at 5 ° S and 103 ° E and is 4 km from the centre of the district government, 32 km from the county capital, and 287 km to the provincial capital. Data collection methods used are methods of surveys, interviews, and GIS while the method of data analysis used is a qualitative descriptive method. The purpose of this research is the development of tourism potentials and make the route of ecotourism Intermap in Pahmungan village. The tools used in this study are GPS (Global Positioning System), Camera, Compass, Laptop, and ArcGis application. The object in this research is the ecotourism object that exists in Pahmungan village that will be obtained through the observation of field surveys and interviews with local communities. The results of this research are reflected in the mapping of tourist interpretation lines in which the mapping is an ecotourism pathway that includes various tours in the village Pahmungan. Ecotourism in the village of Pahmungan is not well managed but there are already several community who began to build the development of tourist destinations especially the waterfall tourism, with the program interpretation programs can support the development of Ecotourism and provide comfort for visitors.
KEANEKARAGAMAN TUMBUHAN PENYUSUN VEGETASI HUTAN LINDUNG BENGKUNAT DI RESOR III KPH UNIT I PESISIR BARAT
Authors: Putri Sesilia Maharani , - Indriyanto 
Published: April 2021

Plant diversity in Protection Forest is an important factor that considered to support the sustainability function to protected the area. Plant diversity is a form of the species association that could be the indicator forest vegetation stabillities. This research aims to analyze the plant diversity in Bengkunat Protection Forest. This research was conducted between March-April 2019 at the 4,470 ha area with the sampling intensity 0.02%. Data were collected using grid line method that consisted of 34 sample plots. Data were analyz using Shannon Index (H), Richness Index (R) and Evenness Index (E). This study found 92 species at the research area. Dipterocarpus haseltii was the most dominant species based on Important Value Index (IVI) of 34.1%. While the average for other types of IVI is only 2.9%. The other dominated species were Polyalthia lateriflora, Dacryodes rostata and Dillenia excelsa. The forest species diversity index (H) was classified as moderate at 1.7, the Richness index (R) was classified as a high level of 30.4 and the evenness index (E) was classified as a high level of 0.9. Based on this research, Bengkunat Protection Forest diversity has a moderated value with the high diversity potential richness and evenness.
Human adipose derived mesenchymal stem cells differentially produced anti-inflammatory oxylipins under proinflammatory stimulation
Authors: Wang Dan , Shen Zhengze , Yu Chaoqun , Cheng Lifang , Chen Daorong , Yuan Zhang 
Published: April 2021

Abstract
MSCs have been proven to have immune modulation and anti-inflammation capabilities, but the mechanisms are still under investigation. Recently, oxylipins have been identified to be involved in the immuno-regulation function of MSCs. In the present research, we employed a newly developed UPLC-MS/MS method to identify and quantify the oxylipin profile of ADSCs under proinflammatory stimulation (TNF-α and IFN-𝛾). As a result, among the analyzed 71 oxylipins, we detected and quantified 49 oxylipins derived from six major n-6 and n-3 polyunsaturated fatty acids (PUFAs) including arachidonic (AA), linoleic (LA), alpha-linolenic (ALA), dihomo-𝛾-linolenic acid (DGLA), eicosapentaenoic (EPA), and docosahexaenoic (DHA) acids in all samples, while 4 oxylipins were detected only in a part of samples and 18 were not detected in all samples. Nine oxylipins were found to be significantly differentially produced in ADSCs after 24 hours of inflammatory stimulation, among which, several oxylipins were reported to be having anti-inflammation or proresolving functions and involved in lipid mediator switching. The results reported here make a fundamental step towards a comprehensive characterization of MSCs derived oxylipins as potential modulators of inflammation and immunoreaction.
Genetic analysis of Sperata sarwari (Singharee) population fragmentized by Physical barriers in the Indus drainage system of Punjab, Pakistan.
Authors: Aziz Asma , Jabeen Farhat , Nafees Muhammad , Sehrish Adiba Khan , Ullah Inayat , Mirza Zahid Sharif , Raza Muhammad Ahmad , Ullah Sami , Afshan Noor 
Published: April 2021

Abstract
Physical barriers like head works, dams barrages are main cause of fragmentation and declining of freshwater fish population in natural habitat. Present study focused on RAPD marker technique to assess the genetic variability among and between the populations of endangered sperata sarwari (Singharee) inhabited in the Indus drainage system of Punjab. Total eight populations (80 speciemen) of S. sarwari were collected from the up and downstream of four Rivers (Chenab, Jhelum, Ravi and Indus) of Punjab. Genomic DNA isolated from muscle tissue of adipose side and ten RAPD marker were used, which produced 50 scorable bands with average band ranging from 250–1050 bp which used for further genetic analysis of S. sarwari. Downstream Indus population of S. sarwari showed highest values of observed alleles (na), effected alleles (ne), Nei’s diversity (h), Shannon index (I) and polymorphism which indicated that downstream Indus population was more genetically variant. The genetic variability (0.5124) and genetic flow (0.4758) among the eight population S. sawari was observed. The up and downstream population showed the highest genetic distance (0.5738) and lowest genetic similarities (0.5634) which indicated complete isolation of Ravi population from other six population. Dendrogram showed that up and downstream Ravi population was completely isolated from the other six up and down stream population of S. sarwai. Overall results indicated that the presence of high fragmentation in River Ravi caused the destruction of habitat and decline in population of S. sarwai in the River Ravi.
Heterogeneous node copying from hidden network structure
Authors: McGillivray Max Falkenberg 
Published: April 2021

Abstract
Node copying is an important mechanism for social network formation, yet most models assume uniform copying rules. Motivated by observations of heterogeneous triadic closure in real networks, we introduce the concept of a hidden network model – a generative two-layer model in which an observed network evolves according to the structure of an underlying hidden layer – and apply the framework to a model of heterogeneous copying. Framed in a social context, these two layers may represent a node’s inner social circle, and wider social circle, such that the model can bias copying probabilities towards, or against, a node’s inner circle of friends. Comparing the case of extreme inner circle bias to an equivalent model with uniform copying, we find that heterogeneous copying suppresses the power-law degree distributions commonly seen in copying models, and results in sparse networks with significantly higher clustering than even the most optimum scenario for uniform copying. Similarly large clustering values are found across a range of real collaboration networks, lending empirical support to the mechanism.
Comparison of obesity indices and triglyceride glucose related parameters to predict type 2 diabetes mellitus among normal-weight elderly in China
Authors: KE Pan , WU Xia , XU Minzhi , FENG Jie , XU Hongbin , GAN Yong , WANG Chao , DENG Zhenyu , LIU Xiang , FU Wenning , TIAN Qingfeng , HE Yan , ZHONG Lirong , JIANG Heng , LU Zuxun 
Published: April 2021

Abstract
Purpose: Although a significant proportion of type 2 diabetes mellitus (T2DM) cases arose from normal-weight individuals, studies on indicators that can predict T2DM in normal-weight people are limited. Accordingly, this study aims to investigate the predictive value of obesity indices and triglyceride glucose related parameters (TyG-related parameters) in T2DM among normal-weight Chinese elderly.Methods: A total of 24,215 normal-weight Chinese elderly (age ≥ 60 years) [body mass index--BMI (18.5-23.9 kg/m2)] were included. Obesity indices and triglyceride glucose related parameters (TyG-related parameters) included waist circumference (WC), waist-to-height ratio (WHtR), visceral adiposity index (VAI), lipid accumulation product (LAP), and TyG-related parameters (TyG, TyG-BMI, TyG-WC, and TyG-WHtR). Multivariate logistic regression analysis was performed to examine the associations between obesity-and TyG-related indices and T2DM. The areas under the curve (AUC) of the receiver-operating characteristic (ROC) curve analyses were used to evaluate and compare the predictive value of the different indices. Results: The prevalence of T2DM was 14.2% in normal-weight individuals. Among the indices, TyG was significantly associated with T2DM among men and women, respectively (adjusted odds ratio--aOR 19.005; 95% CI 13.235–27.291) and (aOR 25.262; 95% CI 16.957–37.634). Compared with other indices, TyG had the highest AUC value for T2DM in men (AUC: 0.818, 95% CI 0.810–0.825) and women (AUC: 0.824, 95% CI 0.814–0.833).Conclusions: TyG is an effective marker and outperforms than other indices when predicting T2DM in the normal-weight Chinese elderly population.Level of evidence: Level V
The impact of COVID 19 pandemic on pattern of cancer mortality in Najran, Saudi Arabia: a single-cancer center experience
Authors: Badheeb Ahmed M , Badheeb Mohamed A , Alhakimi Hamdi A 
Published: April 2021

Abstract
Background: The aim of this paper is to compare the patterns and determinants of cancer mortality in Najran region before and after the COVID-19 epidemics. The association between cancer mortality and each of age, sex, site of cancer, stage, and the 30-days survival rate after the last dose of chemotherapy were assessed.Materials & Methods: Adult cancer patients who died of cancer in King Khalid Hospital in Najran Saudi Arabia, were included in this retrospective observational study. We compared mortality patterns in a period of 6 months in 2020 (March to August) with the corresponding period of 2019.Results: 50 dead adult cancer patients were included, 24 in 2019 and 26 in 2020. Among them, 21% vs 42% were younger than 65 years of age; 61% vs 62% were males, for the years 2019 & 2020 respectively. The top three killers in 2019 were colorectal, gastro-esophageal cancers, and hepatocellular carcinoma, while in 2020 were colorectal, hepatocellular carcinoma, and lymphomas. About 16.7% of patients died within 30 days of receiving anti-cancer treatment in 2019 in comparison with 7.7% in 2020. The difference in the 30-days mortality after receiving anti-cancer treatment was not statistically significant between 2019 and 2020 (p = 0.329).Conclusion: The Year 2020, the time of the COVID-19pandemic, was not associated with a significant increase in short-term mortality among patients with malignancy in Najran, Saudi Arabia. Our results generally reflect the crucial role of strict preventive national measures in saving lives and warrants further exploration.
Intramedullary Nailing for Pathological Fractures of the Proximal Humerus caused by Multiple Myeloma: A Case Report and Literature Review
Authors: xu guoqiang , wang gang , bai xiaodong , liu zhenyu , wang xinjia , wang baojun 
Published: April 2021

Abstract
BackgroundMultiple myeloma bone disease(MMBD) is indicative of multiple myeloma (MM), and it will reduce patient life quality. In addition to oncological, antineoplastic systemic therapy, surgical therapy in patients with MM represents an essential treatment pillar within the framework of supportive therapy measures and is the task of orthopedic tumor surgery. Nevertheless, there are few reports about applying intramedullary (IM) nailing in treating MM-induced proximal humeral fracture to prevent fixation loss. This paper aims to describe a case of pathological fracture of the proximal humerus caused by multiple myeloma effectively treated with IM nailing without removal of tumors and review the current literature.Case presentationThis study reported a 64-year-old male patient complaining of serious left shoulder pain and limited movement. X-ray films showed left proximal humeral fracture accompanying with osteoporosis and bone destruction. During the preoperative examinations, tumor markers, whole-body bone imaging and bone marrow biopsy were performed. The patient was finally diagnosed with multiple myeloma (IgAλ, IIIA/II). After the treatment of pathological fracture with IM nailing, the patient's function recovered and the pain was relieved rapidly. The visual analogue scale (VAS) reduced by 7 points to 2 points postoperatively compared with that preoperatively. Histopathological examination results presented plasma cell myeloma. Next, the patient received chemotherapy in the hematology department. Humeral fracture displayed good union in the 40-month follow-up, with complete healing of fracture, and the clinical outcome was still satisfactory.ConclusionThe pathological fracture of proximal humerus caused by multiple myeloma should be treated by surgery early. IM nail can be used for this kind of fracture without removal of tumors, bone cement augmentation for bone defect or local adjuvant therapy was also employed. Under the combined treatment, the proximal humerus fracture can eventually heal.
The synergistic anticancer traits of graphene oxide plus doxorubicin against BT474 and MCF7 breast cancer stem cells in vitro
Authors: Ebrahimi Mahsa , teimouri maryam , Pooladi Mehdi 
Published: April 2021

Abstract
Breast cancer is among leading causes of death due to cancers around the globe. Current therapeutic approaches towards healing of breast cancer have been associated with poor outcomes. Graphene and its derivatives have a two-dimensional flat structure, which is characterized by the ability to carry drugs and modify the surface, low cytotoxicity and high biocompatibility. This study was performed on MCF7 and BT474 human breast cancer cells. Different concentrations of doxorubicin (DOX), graphene oxide (GO) and graphene oxide plus doxorubicin (GO-DOX) were subjected to both cell lines at specified intervals. At the end of the treatments, MTT test was applied to determine the viability of cells and then flow cytometry, colony formation and spheroid tests were implemented for both cell lines treated with DOX, GO and GO-DOX components. We used DLS and TEM to confirm the GO properties. According to the MTT test results, 1 µL of DOX at 10 mg /mL (equivalent to 0.1 mg / mL) caused 50% survival of MCF7 cells at 24 hours. In both cell lines, an increase in apoptosis occurred after incubation with GO and DOX. Although, a rate of mortality of MCF-7 cells was due to necrosis, the BT474 cells death was merely through the apoptosis. Furthermore, the results of colony formation test outlined an enhancing inhibitory effect in the presence of GO-DOX as a comparison to the control. Additionally, spheroids formed following treatment with GO-DOX exhibited a significant decrease compared to their control group; with an increase in the number of spheroids in BT474 cells compared to those in the MCF-7. The decreasing effect of compounds against the migration and cell invasion potential was also observed, being higher in MCF7 than BT474 cells. The effects of cytotoxic GO were observed at higher concentrations.
Prebiotic potential and other health benefits of prebiotic mixture of pigeon pea (Cajanus cajan L) in Wistar NIN rats
Authors: Shakappa Devindra , Talari Aruna , Naik Rakesh 
Published: April 2021

Abstract
The legume prebiotics, especially galacto-oligosaccharides, are the center of health since they play a crucial role in maintaining gut health. The aim of the present study was to understand the role of prebiotic galacto-oligosaccharides of pigeon pea (Cajanus cajan L) on gut microbiota, obesity and type 2 diabetes mellitus in Wistar National Institute of Nutrition NIN rats. Proximate composition and oligosaccharide content of the pigeon pea was estimated and for animal experiment, four-week-old weaning male Wistar National Institute of Nutrition NIN rats (N = 36) were divided equally into three groups (n = 12) control, raffinose, and pigeon pea prebiotics groups. All the groups were fed with the respective diet for 18 weeks. After 18 weeks 5 ml of blood was drawn from the retro-orbital plexus and the rats were sacrificed by (CO2) inhalation. Among the studied groups, the pigeon pea prebiotic supplementation significantly (p˂0.05) lowered body weight gain (284.7 ± 36.4 grams) and resulted in lower body mass index (3.79 ± 0.18kg / m2). The fat percent was significantly lower in pigeon pea prebiotic fed group (7.8 ± 2.7) than raffinose (11.6 ± 3.1) and control (13.8 ± 2) groups. Pigeon pea prebiotic feeding significantly (< 0.05) lowered blood glucose levels; it also improved the Homeostasis model assessment of insulin resistance (HOMA IR) index in pigeon pea prebiotic group (32.08 ± 5.37). Pigeon pea prebiotic feeding significantly (p˂0.05) enhanced the fold increase of lactobacillus and bifidobacterial count when compared to raffinose fed group. The present study explores the role of pigeon pea prebiotics on gut microbiota and the regulation of some of the features of metabolic syndrome such as obesity and diabetes.