bluuebunny/crossref_metadata_2025_split huggingface dataset:
Solving localized wave solutions of the derivative nonlinear Schrodinger equation using an improved PINN method
Authors: Pu J.C. , Li J. , Chen Y. 
Published: April 2021

Abstract
The solving of the derivative nonlinear Schrodinger equation (DNLS) has attracted considerable attention in theoretical analysis and physical applications. Based on the physicsinformed neural network (PINN) which has been put forward to uncover dynamical behaviors of nonlinear partial different equation from spatiotemporal data directly, an improved PINN method with neuron-wise locally adaptive activation function is presented to derive localized wave solutions of the DNLS in complex space. In order to compare the performance of above two methods, we reveal the dynamical behaviors and error analysis for localized wave solutions which include one-rational soliton solution, genuine rational soliton solutions and rogue wave solution of the DNLS by employing two methods, also exhibit vivid diagrams and detailed analysis. The numerical results demonstrate the improved method has faster convergence and better simulation effect. On the bases of the improved method, the effects for different numbers of initial points sampled, residual collocation points sampled, network layers, neurons per hidden layer on the second order genuine rational soliton solution dynamics of the DNLS are considered, and the
relevant analysis when the locally adaptive activation function chooses different initial values of scalable parameters are also exhibited in the simulation of the two-order rogue wave solution.
Prey Abundance Regulating the Response of an Important Marine Eel Species Conger Myriaster Growth to Water Temperature
Authors: Mu Xiuxia , Zhang Chongliang , Xu Binduo , Ji Yupeng , Xue Ying , Ren Yiping 
Published: April 2021

Abstract
Whitespotted conger (Conger myriaster) is a commercially important species in East Asia but the fisheries stock has drastically declined in recent years. Environmental changes are assumed to have profound impacts on the growth pattern of this species, yet the mechanisms that regulate growth remain poorly understood. Here we used otolith measurements to establish growth chronologies of 9-year period (2010–2018) for whitespotted conger in the Yellow Sea and evaluated the effects of environmental variables on the growth pattern. Linear mixed-effects models were used to explain growth variation with abiotic and biotic environmental variables, including seasonal water temperature, prey availability, and population density, and to assess age-dependent responses in growth and the interactions between abiotic and biotic factors. The results indicated that the growth of whitespotted conger positively correlated with spring sea bottom temperature (March-May) and prey per capita, and the influence of prey availability became larger with increasing ages. The model detected significant negative interactions between sea temperature and prey availability, indicating a higher degree of temperature-dependent growth when prey availability was low. Our findings imply that the growth of whitespotted conger is less likely to be influenced by food availability when the spring water temperature is high in the Yellow Sea, and a combination of cold spring and low food availability may result in substantial constrained growth. This study provided the first evidence for the joint effects of abiotic and biotic factors on the growth variation of whitespotted conger, and the information may contribute to sustainable management policies.
Investigation the effects of cation/anion structure on distribution of Thiophene between IL-rich and Hydrocarbon-rich phases by QSPR approach
Authors: Moheb-Aleaba Zahra , Khosravi-Nikou Mohammadreza 
Published: April 2021

Abstract
Selecting an appropriate ionic liquid as extraction solvent for extracting sulfur compounds from fuel, is a promising way to reduce SOx emissions and to prevent environmental pollution. In this regard, the best structural descriptors of different cation and anion, which play an important role on the thiophene distribution between ionic liquid (IL) and hydrocarbon phases in the ternary systems, that is helpful for selecting a proper IL, have been investigated using quantitative structure − property relationship (QSPR) approach. Five different datasets were collected from the literature containing {(Cation/[NTf2] − thiophene − n-heptane), (Cation/[NTf2] − thiophene − n-hexane), (Cation/[FAP] − thiophene − n-heptane), (Cation/[TCM] − thiophene − n-heptane), ([C2MIM]/Anion − thiophene − hydrocarbon), ([C8MIM]/Anion–thiophene − hydrocarbon)} with 664 data points. By investigating the various kinds of molecular descriptors of 1D, 2D and 3D, it was found that the increment of Spanning Tree Number (STN) descriptor as cation structure descriptor, causes a decrease in mole fraction of thiophene in IL-rich phase due to the increase in steric hindrance. STN descriptor reflects the complexity of structure of cation and the information about steric hindrance. Also, it was found that an increase in E1p value as anion structure descriptor leads to the decrement of mole fraction of thiophene in IL-rich phase, in order to increase the interaction between cation and anion in ionic liquid, that reduced the available space of cation to interact with thiophene. The E1p descriptor represents the density of atoms projected along the length or unfilled space of the anion, thus it is informative of the accessibility of them by thiophene.
MarkerCount: A stable, count-based cell type identifier for single cell RNA-Seq experiments
Authors: Kim Hanbyeol , Lee Joongho , Kang Keunsoo , Yoon Seokhyun 
Published: April 2021

Abstract
Cell type identification is a key step to downstream analysis of single cell RNA-seq experiments. Indispensible information for this is gene expression, which is used to cluster cells, train the model and set rejection thresholds. Problem is they are subject to batch effect arising from different platforms and preprocessing. We present MarkerCount, which uses the number of markers expressed regardless of their expression level to initially identify cell types and, then, reassign cell type in cluster-basis. MarkerCount works both in reference and marker-based mode, where the latter utilizes only the existing lists of markers, while the former required pre-annotated dataset to train the model. The performance was evaluated and compared with the existing identifiers, both marker and reference-based, that can be customized with publicly available datasets and marker DB. The results show that MarkerCount provides a stable performance when comparing with other reference-based and marker-based cell type identifiers.
Mapping Research Evidence on Children Living With Autism Spectrum Disorders in Africa: a Scoping Review Protocol.
Authors: Laari Luke , Kuupiel Desmond , Boso Christian Makafui 
Published: April 2021

Abstract
Background: Early detection and intervention of children living with Autism Spectrum Disorders have shown a great improvement of the child's behaviour, predominantly in language and motor skills development. We are proposing to conduct a systematic scoping review that will map all evidence available on children living with Autism Spectrum Disorders in Africa.Methods and analysis: This study will be guided by Arksey and O’Malley’s framework of scoping reviews. A comprehensive literature search will be done in the following electronic databases. Cumulative Index to Nursing and Allied Health Literature (CINAHL), Science Direct, EBSCOhost, MEDLINE, Health Sources, and Google Scholar. Primary studies, published in peer-reviewed journals and grey literature such as unpublished studies, studies in press and Theses that address our research question will be included. To reduce research bias two independent reviewers will perform title, abstract, and full article screening in parallel. Data extraction from the selected studies will be conducted by two independent reviewers. NVivo version 12 software will be used to assist with the extraction of relevant answers to the study questions from selected studies using content thematic analysis. The results for this planned study will be presented following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Extension for Scoping Review (PRISMA-ScR). Mixed Methods Assessment Tool version 2018 will be used for quality appraisal of included studies.Discussion: We anticipate that the proposed mapped evidence on Children living with Autism Spectrum Disorders in Africa will reveal indicators for early detection that would facilitate strategies for intervention. We are also anticipating that this systematic scoping review will reveal gaps that can be addressed to ensure context-sensitive interventions and identify caregiver burdens of children living with Autism. This will contribute to the reduction of a scarcity of literature on children living with Autism in Africa.
Factorial structure and internal consistency of the Russian version of Teachers Creativity Nurturing Behavior Scale (TCNB)
Authors: Sharma Sandeep , Sharma Ekta , Mirosnik kiril 
Published: April 2021

Abstract
Creativity is valued as one of the key 21st-century skills. Though the importance of creativity and creativity nurturing is well-accepted yet it remains the unachieved standard for educational systems.Various factors contribute to fostering creative behavior but the role of a teacher is critical and crucial in nurturing the creative potential of the child. Thecurrent study aimsto adapt the Teachers Creativity Nurturing Behavior Scale (TCNB) in Russian and evaluate its psychometric properties. Factorial structure and internal consistency of the Russian TCNB were examined in the sample of 223 school teachers from 86 towns and rural areas of the Russian Federation and the Commonwealth of Independent States countries (88.8% females, Mage = 36.91, SDage = 10.57). The teaching experience of participants varied from 1 to 43 years (M = 14.39, SD = 10.58). The factorial structure of the TCNB was assessed by exploratory factor analysis, and the internal consistency was estimated by the omega coefficient. Results showed that the four-factor structure was the most appropriate given the data. The value of internal consistency reliability variedfrom .62 to .83 for different factors, providing evidence of acceptable consistency of the scale. Overall, this study demonstrated preliminary evidence of the psychometrical characteristics of the Russian TCNB. The discrepancies between English and Russian versions of TCNB, limitations of the study, and future research perspectives are discussed.
Impact evaluation of immunisation service integration to nutrition programmes and pediatric outpatient departments of primary health care centers in Rumbek East and Rumbek Centre counties of South Sudan
Authors: IDRIS ISRAEL OLUWASEYIDAYO , Lamidi Serifu Ayobami , Ochagu Victor A , Tapkigen Janet , Obwoya Justin Geno , Abbas Kaja 
Published: April 2021

Abstract
Objective:To evaluate the impact of immunisation service integration to nutrition programmes and under 5-year-old outpatient departments of primary health care centres in Rumbek East and Rumbek Centre counties of South Sudan.Design:A retrospective intervention study was conducted in selected primary health care centers (PHCCs).Setting:The study was conducted in 3 primary healthcare centres in Rumbek East county and 3 primary healthcare centres in Rumbek Centre county in Lakes state of South Sudan.Participant:We extracted the data for the uptake of pentavalent vaccine (1st, 2nd and 3rd dose) given to children between 6 weeks old to 23 months old from immunisation records for January to June 2019 before immunisation service integration and July 2019 to December 2019 after immunisation service integration on the District Health Information System 2 (DHIS2) website to estimate the immunisation uptake ratio and drop-out rate.Results:The uptake of the first dose of the pentavalent vaccine improved from 61–96% (p < 0.001) after immunisation service integration into the nutrition programmes of the primary health care centers in Rumbek Centre county. The uptake of the second pentavalent dose improved from 37–69% (p = 0.102) and for the third pentavalent dose from 36–62% (p < 0.001), while the drop-out rate reduced from 57–40% (p < 0.001). While in Rumbek East county, the uptake of the first dose of the pentavalent vaccine improved from 55–77% (p < 0.001) after immunisation service integration into the under 5-year-old pediatric outpatient departments. The uptake of the second dose improved from 36–62% (p < 0.001) and for the third dose from 44–63% (p < 0.001), while the drop-out rate reduced from 40–28% (p < 0.001). Children were 23% more likely (RR: 1.23 [95% CI: 1.01–1.50]) to have been immunised with the first dose of the pentavalent vaccine upon immunisation service integration into the nutrition programmes of primary health care centers of Rumbek Centre county in comparison to integration into under 5-year-old outpatient departments of Rumbek East county.Conclusion:Integration of immunisation service delivery to nutrition sites and children’s outpatient departments improved the immunisation coverage and decreased drop-out rate. Stakeholders of the extended programme on immunisation should focus on the sustainability and scale-up of this intervention as it has high potential to improve childhood immunisation coverage and lower the high rates of vaccine preventable deaths among the children in South Sudan.
Determining the Role of Natural SARS-CoV-2 Infection in the Death of Ten Domestic Pets
Authors: Carpenter Ann , Ghai Ria , Gary Joy , Ritter Jana , Carvallo Francisco , Diel Diego D. , Martins Mathias , Murphy Julia , Schroeder Betsy , Brightbill Kevin , Tewari Deepanker , Boger Lore , Gabel Julie , Cobb Robert , Hennebelle Janemarie , Stanton James B. , McCullough Kathryn , Mosley Yung-Yi C. , Naikare Hemant K. , Radcliff Rachel , Parr Boyd , Balsamo Gary , Robbins Brent , Smith David , Slavinski Sally , Williams Carl , Meckes Doug , Jones Dee , Frazier Tony , Steury Kelley , Rooney Jane , Torchetti Mia , Wendling Natalie , Currie Dustin , Behravesh Casey Barton , Wallace Ryan 
Published: April 2021

Abstract
Transmission of SARS-CoV-2, the virus that causes COVID-19, from people to companion animals has been reported globally. Between March 2020 and January 2021, the United States reported 94 companion animals with SARS-CoV-2. While most animals with SARS-CoV-2 have mild illness, 10 animals (5 dogs, 5 cats) died around the time of SARS-CoV-2 diagnosis. In one dog, histopathologic changes suggest SARS-CoV-2 exacerbated a severe chronic respiratory disease and contributed to death. In one cat, SARS-CoV-2 was associated with histopathologic changes suggesting the virus caused clinical signs that resulted in euthanasia. In the remaining eight animals, SARS-CoV-2 infection was an incidental finding (4 dogs, 4 cats). This report provides evidence that in rare circumstances, SARS-CoV-2 can contribute to or cause death in companion animals with underlying conditions.
Fuzzy numerical solution to the unconfined aquifer problem under the Boussinesq equation
Authors: Samarinas N. , Tzimopoulos C. , Evangelides C. 
Published: April 2021

Abstract
In this article, the fuzzy numerical solution of the linearized one-dimensional Boussinesq equation of unsteady flow in a semi-infinite unconfined aquifer bordering a lake is examined. The equation describing the problem is a partial differential parabolic equation of second order. This equation requires knowledge of the initial and boundary conditions as well as the various soil parameters. The above auxiliary conditions are subject to different kinds of uncertainty due to human and machine imprecision and create ambiguities for the solution of the problem, and a fuzzy method is introduced. Since the physical problem refers to a partial differential equation, the generalized Hukuhara (gH) derivative is used, as well as the extension of this theory regarding partial derivatives. The objective of this paper is to compare the fuzzy numerical and analytical results, for two different cases of the physical problem of an aquifer's unsteady flow, in order to prove the reliability and efficiency of the proposed fuzzy numerical scheme (fuzzy Crank–Nicolson scheme). The comparison of the methods is based on the transformed Haussdorff metric, which shows that the distances between the analytical and numerical results tend to zero.
Silage of the organic fraction of municipal solid waste to improve methane production
Authors: Castellón-Zelaya Mario F. , González-Martínez Simón 
Published: April 2021

Abstract
The silage of the organic fraction of municipal solid waste (OFMSW) is a common practice in biogas plants. During silage, fermentation processes take place, affecting the later methanisation stage. There are no studies about how OFMSW silage affects methane production. This work aimed to determine the effects of silage (anaerobic acid fermentation) at different solids concentrations and temperatures on methane production. OFMSW was ensiled at 20, 35, and 55 °C with total solids (TS) concentrations of 10, 20, and 28% for 15 days. The ensiled OFMSW was then tested for methane production at the substrate to inoculum ratios (S/I) of 0.5, 1.0, and 1.5. Independently of the temperature, the production of the metabolites during silage increases with decreasing solids concentration. The highest production was of lactic acid, ethanol, and acetic acid, representing together 95% of the total. Methane production from ensiled OFMSW at 10% solids concentration shows, under every tested condition, better methane production than from fresh OFMSW. Ensiled OFMSW produces more methane than fresh OFMSW, and methane production was highest at 35 °C.
Mechanisms Involved in Apice Closure of Pulpless Teeth – Literature Review
Authors: dos Santos Neto Alexandrino Pereira , Maia Sandra Maria Alves Sayão , Leão Jair Carneiro , Quidute Iliana Lins , dos Santos Guimarães Carolina , Júnior Severino Alves , Álvares Pamella Recco , Gomes Ribeiro Maria Izabel , Silva Luciano Barreto 
Published: April 2021

Background:
Unfinished root formation has always offered challenges in endodontics due to technical difficulties and weakened teeth resistance during the lifetime of an individual. Pulp revascularization therapy appeared as a solution for apical closure and root maturation. The existence of oral stem cells involved in the process associated with traditional resident cells requires adequate blood supply given by induced controlled injury deliberately accomplished into the periapical zone.

Objective:
The aim of this work was to research, through literature review, the main mechanisms involved in the process of apical closure through the technique of pulp revascularization.

Conclusion:
Apice closure in pulpless teeth seems to happen as a result of professional intervention and biological activity. The success rate depends on the role of traditional local immune cells and stem cells associated with adequate blood supply to finish root formation.
Performance of QMAC-dRASTTM (Direct Rapid Antimicrobial Susceptibility Testing) - a Newcomer in Phenotypic Automatic AST
Authors: Christensen Jens J. , Junker Hanne , Madsen Connie B. , Christiansen Camilla F. , Kristensen Tina , Lund Tine K. , Fallesen Majbritt , Kjølsen Rie , Hansen Bodil , Hansen Pia K. , Jensen Ulrich S. 
Published: April 2021

Objective:
QMAC-dRASTTM is a phenotypic automatized Antibiotic Susceptibility Testing (AST) system based on microfluidic chip technology enabling observation of changes in a single bacterial cell under antibiotic treatment conditions. The 96 wells plate with dried antibiotics comprises 19 and 17 antibiotics for the Gram-Negatives (GNs) and Gram-Positives (GPs), respectively. Categorical (Sensitive, Intermediate or Resistant) results were compared to results obtained by our laboratory standard susceptibility testing procedure and given as Categorical Agreement (CA).

Methods:
In a 3-month period (2019/2020), blood cultures detected positive were included. Excluded were known off-panel strains of QMAC-dRASTTM, such as Gram-positive bacilli, Streptococcus and Candida species. Percentages of CA (CA, %) between QMAC-dRASTTM and routine testing methods used in the laboratory (EUCAST disc diffusion and/or etest/Broth Micro Dilution MIC), were calculated.

Results:
255 positive blood cultures from as many patients were examined. Of the positive blood culture strains, 144 were GNs, and 111 were GPs. An overall combined CA,% of 96.3 (2410 of 2502 determinations) was obtained, and discrepancies were noted in 92 of 2502 test results (3.7%). The percentage of very major errors (VMEs) was 0.7% for GNs and 2.2% for GPs. For 87% of blood culture specimens examined, susceptibility reports were available within 6-7 hours.

Conclusion:
The high CA,% for as well GNs as GPs are promising. The presented time to report data obtained by QMAC-dRASTTM in this study being of 3-8 hours for blood culture specimens examined strongly support a further possible improvement in the workflow for handling blood stream infections.
Evaluation of CA-125 Biomarker in Acute Appendicitis Patients: Correlation with Clinical Symptoms and Lab Results
Authors: Ahmadinejad Mojtaba , Hashemi Seyed A. , Shirzadi Alireza , Soltanian Ali , Ashrafi Jafar , Kabir Kourosh , Alizadeh Mahla 
Published: April 2021

Objectives:
The aim of this study is to evaluate the diagnostic significance of CA 125 in Acute Appendicitis (AA) along with the changes in its levels about clinical symptoms and lab findings.

Methods:
Patients referred at the emergency department of Madani hospital with the suspicion of AA and right iliac fossa pain were enrolled in this study. Preoperative CA 125 levels along with C-reactive Protein (CRP) and complete blood count were obtained. Lab findings, signs and symptoms were recorded for all the patients. Statistical analysis was conducted based on CA 125 < 16.4 U/mL and ≥ 16.4 U/mL using the logistic regression model, where variables such as fever, anorexia, CRP and Erythrocyte Sedimentation Rate (ESR) were added to the model.

Results:
Of 207 patients with the mean age of 26.55 ± 0.967 years, 48.8% of them were males and 51.20% were females. 122 of the total patients had CA 125 ≥ 16.4 U/mL. Anorexia was significantly associated with increased levels of CA 125. CA 125 was 2.14 times higher in patients presenting anorexia. However, ESR, CRP and fever were not associated with the elevation of CA 125. Based on the contour plot, it was deduced that leukocytosis at its lowest and erythrocyte sedimentation rate at its highest levels is associated with the maximum concentration of serum CA 125.

Conclusion:
Based on the findings from this study, CA 125 cannot be considered as a reliable diagnostic variable for acute appendicitis. Levels of CA 125 may vary with the severity of AA.