bluuebunny/crossref_metadata_2025_split huggingface dataset:
Punggung Sehat dengan Mckenzie Back Exercises Selama Pembelajaran Daring bagi Mahasiswa STIKes Hang Tuah Tanjungpinang
Authors: Siagian Yusnaini , Sitindaon Soni Hendra 
Published: November 2021

Low back pain is pain that originates from the spine in the spinal area, muscles, nerves, tendons, joints, or cartilage due to the wrong position. Individuals who perform activities such as sitting up straight and bending over must be in the correct position. At Stikes Hang Tuah Tanjungpinang, a phenomenon was found that 42.7% of students complained of lower back pain due to wrong sitting habits such as sitting in a bent position when attending online lectures and doing college assignments. Sitting for too long in the wrong position causes muscle tension and spinal ligament strain. The results of interviews with students, most of the students who complain of low back pain do not understand what can be done to reduce or prevent low back pain due to sitting position and sitting too long. One of the non-pharmacological therapies to treat low back pain is McKenzie back exercises. The purpose of this community service is to provide students with an understanding of low back pain and teach actions to reduce or prevent low back pain. The success indicator of this activity is that students understand and can perform the McKenzie back exercises The method used is to provide health education about low back pain and demonstrate McKenzie back exercises to students.
ANALISIS KERUSAKAN PADA RANTAI CONVEYOR
Authors: Amir  , Murtalim  , Muhammad chusnan Apriyanto  , Muhamad Arif Rahman  , Abel Alfarez  
Published: November 2021

Conveyor adalah suatu sistem mekanik yang mempunyai fungsi memindahkan barang dari suatu tempat ke tempat lain. Conveyor banyak dipakai di industri untuk transportasi barang yang jumlahnya sangat banyak dan berkelanjutan. Banyak jenis coveyor yang di gunakan di dunia industri di antara nya conveyor yang berbentuk rantai dengan disc teplon di selang satu setiap rangkaian rantai nya yang berjalan di dalam pipa. Untuk mengetahui penyebab kerusakan pada bagian rantai vonveyor tersebut, maka dilakukan beberapa pengujian seperti pengujian komposisi kimia, pengujian metalografi, pengujian kekerasan.
Berdasarkan pengamatan secara visual dan Pengujian komposisi kimia, Pengujian metalografi, pengujian kekerasan, dan analisa terhadap material rantai konveyor yang mengalami patah/putus, maka dapat disimpulkan sebagai berikut: Penyebab terjadinya patah/putusnya rantai konveyor yaitu dikarenakan material rantai konveyor tersebut memiliki konsentarsi tegangan dan kekerasan yang tinggi sehingga menjadi daerah yang rawan dan kritis terhadap fatique akibat tidak adanya PWHT (Post Welding Heat Treatment), tinginya nilai kekerasan pada daerah HAZ ini dapat mengakibatkan dearah tersebut semakin rentan terhadap putusnya material rantai konveyor tersebut.
Kata kunci: rantai, conveyor, komposisi kimia, metalografi, kekerasan
Torque Analysis of 2 KW BLDC (Brushless Direct Current) Motor with Speed Variations in Electric Cars E-Falco
Authors: Darmono Bambang , Pranoto Hadi , Arifin Zainal 
Published: November 2021

The motor releases torque and power to drive an electric car by carrying the load from a start position until it travels at the desired speed. The KMLI E-Falco electric car uses a BLDC type electric motor with a power capacity of 2 kW. To find out the amount of torque of a 2 kW BLDC motor when driving with variations in speed, it can be done by manual calculations using the torque equation and doing a dynotest test. The dynotest results show that the motor torque at the speed: 1 km/h is 1 Nm, 10 km/h is 131 Nm, 13 km/h is 228 Nm, 20 km/h is 225 Nm, 30 km/h is 219 Nm, 40 km / h is 188 Nm, 50 km / hour is 145 Nm, 60 km / h is 113 Nm, and 70 km / h is 85 Nm. From the results of the dynotest, it shows that the peak torque occurs at a speed of 13 km / h at 228 Nm. Racing software installed in the controller can increase the motor torque by four times at a speed variation of 13-70 km/h based on the results of the dynotest above. Keywords: motor, BLDC, torque, speed, acceleration.
Au-delà de la déroute afghane
Authors: David Dominique 
Published: November 2021

La débâcle américano-occidentale en Afghanistan nous contraint à réfléchir sur nos engagements extérieurs. Depuis plusieurs décennies, les échecs se multiplient. Il s’agit de « retrouver le monde réel » et non celui que « nous rêvons d’offrir ». Nous ne sommes plus le centre d’un monde que nous pourrions remodeler seuls. Un multilatéralisme est à reconstruire, sur des bases concrètes et à partir d’un diagnostic réaliste.
Histoire militaire
Authors: Franc Claude 
Published: November 2021

Bien que « capital ship » des marines au début de la Seconde Guerre mondiale, les cuirassés ont montré leur vulnérabilité face à l’aviation embarquée dès 1940. Pour autant, les marines mirent du temps à prendre en compte le déclassement de ces navires, quintessence de la construction navale depuis le milieu du XIX e siècle.
First Identification of the Effects of Low Frequency Electromagnetic Field on the Micromolecular Changes in Adipose Tissue-Derived Mesenchymal Stem Cells by Fourier Transform Infrared Spectroscopy
Authors: Łach Kornelia , Cebulski Józef , Chaber Radosław , Kocan Beata , Wojnarowska-Nowak Renata , Banaś-Ząbczyk Agnieszka 
Published: November 2021

Purpose:
In this study, we hypothesize that exposure of adipose tissue-mesenchymal stem cells (AT-MSCs) to electromagnetic field (EMF) may impact adipose stem cells' micromolecular structure (analyzed using Fourier transform infrared spectroscopy [FTIR]).

Materials and Methods:
The AT-MSCs were exposed to continuous vertically applied sinusoidal EMF with a frequency of 50 Hz and a flux density of 1.5 mT for 24, 48, and 72 h. After an appropriate time (24, 48, 72 h) cells were washed with PBS, scrubbed, and immediately taken into FTIR analyses.

Results:
EMFs affect AT-MSCs. The greatest differences were in the range of nucleic acids and proteins in the fingerprint region which occurred after 24 and 48 h of EMF exposure. However, in the case of 72 h of EMF exposure, no significant differences were noticed in the FTIR spectra towards the control.

Conclusions:
FTIR spectra show differences between samples under the influence of EMF before they will be manifested at the morphological level. The largest differences in the range of nucleic acids and proteins in the fingerprint region occurred at 24 and 48 h of EMF exposure. That means it was during the first 48 h after EMF exposure a great number of dynamic changes occurred. However, in the case of AT-MSCs in 72 h EMF and 72 h control, no significant differences were noted in the FTIR spectra, which means that the chemical composition in these two cases is similar. EMF is not neutral for stem cells, especially in the in the first hours of interaction (24 h, 48 h).
Surface Dose Measurements in Chest Wall Postmastectomy Radiotherapy to Achieve Optimal Dose Delivery with 6 MV Photon Beam
Authors: Lobo Dilson , Banerjee Sourjya , Srinivas Challapalli , Athiyamaan M. S. , Reddy Shreyas , Sunny Johan , Ravichandran Ramamoorthy , Kotian Himani , Prakash Saxena PU 
Published: November 2021

Aim:
A tissue-equivalent bolus of sufficient thickness is used to overcome build up effect to the chest wall region of postmastectomy radiotherapy (PMRT) patients with tangential technique till Radiation Therapy Oncology Group (RTOG) Grade 2 (dry desquamation) skin reaction is observed. The aim of this study is to optimize surface dose delivered to chest wall in three-dimensional radiotherapy using EBT3 film.

Materials and Methods:
Measurements were conducted with calibrated EBT3 films with thorax phantom under “open beam, Superflab gel (0.5 cm) and brass bolus conditions to check correlation against TPS planned doses. Eighty-two patients who received 50 Gy in 25# were randomly assigned to Group A (Superflab 0.5 cm gel bolus for first 15 fractions followed by no bolus in remaining 10 fractions), Group B or Group C (Superflab 0.5 cm gel or single layer brass bolus, respectively, till reaching RTOG Grade 2 skin toxicity).

Results:
Phantom measured and TPS calculated surface doses were within − 5.5%, 4.7%, and 8.6% under open beam, 0.5 cm gel, and single layer of brass bolus applications, respectively. The overall surface doses (OSD) were 80.1% ±2.9% (n = 28), 92.6% ±4.6% (n = 28), and 87.4% ±4.7% (n = 26) in Group A, B, and C, respectively. At the end of treatment, 7 out of 28; 13 out of 28; and 9 out of 26 patients developed Grade 2 skin toxicity having the OSD value of 83.0% ±1.6% (n = 7); 93.7% ±3.2% (n = 13); and 89.9% ±5.6% (n = 9) in Groups A, B, and C, respectively. At the 20th–23rd fraction, 2 out of 7; 6 out of 13; and 4 out of 9 patients in Groups A, B, and C developed a Grade 2 skin toxicity, while the remaining patients in each group developed at the end of treatment.

Conclusions:
Our objective to estimate the occurrence of optimal dose limit for bolus applications in PMRT could be achieved using clinical EBT3 film dosimetry. This study ensured correct dose to scar area to protect cosmetic effects. This may also serve as quality assurance on optimal dose delivery for expected local control in these patients.
Genotoxicity in Oral Mucosal Epithelial Cells of Petrol Station Attendants
Authors: Rehani Shweta , Raj Naresh , Jeergal Prabhakar , Sharma Mohit , Bishen Kundendu Arya , Nagpal Ruchi 
Published: November 2021

Introduction:
Occupational exposure to petrol derivatives possesses an increased risk of various cancers including that of the oral mucosa. Scientific studies have shown the correlation of micronuclei assay (MN) with the cytogenotoxic changes in petrol station attendants. However, very few have reported the use of MN assay as a promising tool for assessing the impact of smoking in these workers.

Aim:
To explore the cytogenotoxic damage in exfoliated buccal cells obtained from petrol station attendants and control subjects using the MN assay along with additional effects due to smoking.

Materials and Methods:
The study comprised 60 males who were divided into Group I–IV with each having 15 subjects. These subjects were categorized as exposed smokers, exposed nonsmokers, unexposed smoker group, and unexposed nonsmokers. The MN and additional nuclear abnormalities (karyorrhexis [KH], binucleation [BN], pyknosis [P], and karyolysis [KL]) were calculated in PAP-stained slides.

Results:
Statistically higher mean frequencies of overall nuclear anomalies were observed in petrol pump workers in comparison with the control group. Petrol pump smokers carry the highest nuclear anomalies followed by non-exposed smokers than exposed non-smokers and the count was the least among unexposed non-smoker workers.

Discussion and Conclusion:
The present study indicated that the petrol pump workers are under higher cytogenotoxic damage. Also, smoking added to the frequency of damage. Thus, MN and other nuclear anomalies are in-vitro reliable biomarker assays available and should be routinely employed as a screening tool in their periodic medical evaluation.
Comparison of gastric motility in patients of type 2 diabetes mellitus with various degrees of glycemic control
Authors: Jain Sanchay , Dhingra Vandana , Kant Ravi , Kumari Ranjeeta 
Published: November 2021

AbstractThe aim of this study was to evaluate the effect of glycemic control as estimated by glycated hemoglobin A1c (HbA1c) on gastric emptying in patients with type 2 diabetes mellitus (DM) using gastric emptying scintigraphy (GES). This was a cross-sectional study conducted at a tertiary health care center in Northern India. The study included 44 patients who underwent GES using a radiolabeled solid Idli meal containing 1 mCi of Tc-99 m Sulfur Colloid. Patients were divided into three groups based on glycemic control as Group A, B, and C with HbA1c <7%, 7%–9%, and >9%. Statistical analysis was performed using the IBM® SPSS® Statistics Version 23.0 The comparison of proportions was done using the Chi-square test and Fisher's exact test. Means were compared using the independent t-test and one-way analysis of variance. P < 0.05 was considered statistically significant. No statistically significant correlation was found between delayed gastric emptying and glycemic control (P = 0.09), gender (P = 0.228), dietary patterns (P = 0.91), symptoms of gastroparesis (P = 0.06), body mass index (BMI) (P = 0.267), and duration of type 2 DM (P = 0.565). No statistically significant association was also found between glycemic control and time taken for half gastric emptying (t1/2) (P = 0.225). Scintigraphy using Tc-99m Sulfur Colloid radiolabeled Idli meal can be effectively used for the assessment of gastric emptying. There is no significant correlation of delayed gastric emptying with glycemic control, gender, BMI, type of diet, and duration of diabetes mellitus.
Discordant findings of different positron emission tomography/CT tracers in a case of glioblastoma
Authors: Kumar Ram , Gupta Nitin , Ranjan Rajeev , Verma Ritu , Belho Ethel , Sen Ishita 
Published: November 2021

Abstract
18F-2-fluoro-2-deoxy-D-glucose ([18F]-FDG) positron emission tomography (PET) CT has proven useful in the evaluation of high-grade glioma and is also useful as a predictor of the degree of malignancy in newly diagnosed brain tumors. It is commonly accepted that high-grade gliomas are characterized by increased FDG uptake, whereas the low-grade glioma demonstrates reduced or absent FDG uptake. [18F]-FDOPA is an amino acid PET tracer which is a marker of the proliferative activity of brain tumors and demonstrates positive uptake in all grades of brain tumors; however, the degree of tracer uptake is significantly higher in high-grade tumors as compared to low-grade tumors. Here, we discuss a case where both FDG and DOPA PET/CT scans raised suspicion of low-grade glioma; however, the final histopathology report confirmed WHO grade IV Glioblastoma.
Clinicopathological features and outcome of thyroglobulin elevation and negative iodine scintigraphy (TENIS) patients with negative neck ultrasound: Experience from a thyroid carcinoma clinic in India
Authors: Vijayan Roopa , Palaniswamy Shanmuga , Vadayath Usha , Nair Vasantha , Kumar Harish 
Published: November 2021

AbstractManagement of differentiated thyroid carcinoma (DTC) patients with thyroglobulin (Tg) elevation and negative iodine scintigraphy (TENIS) and negative neck ultrasound scan causes considerable diagnostic and therapeutic dilemma, especially in resource-poor settings. The aim of this study was to evaluate clinicopathological features and outcome of TENIS patients with negative neck US attending a thyroid cancer clinic in India. From a DTC database of 722 containing 193 TENIS patients, subjects with negative neck US and negative Tg antibody (TgAb) were selected retrospectively and analyzed using appropriate statistical methods. The study group included 64 patients (male – 17, female – 47, mean age – 44.7 ± 12.8 years) with 54 papillary and 10 follicular thyroid carcinomas, American Thyroid Association (ATA) recurrence risk categorization (2009) – low – 16, intermediate – 28, and high – 2 0. Most of the patients became TENIS within 1 year of diagnosis with median Tg level of 6.5 ng/mL (1.2–996 ng/mL) and mean follow-up of 7.8 years. On follow-up, Tg dropped spontaneously in 27 patients, more among the low and intermediate-risk categories. For those with high or increasing Tg level, further imaging (fluorodeoxyglucose positron emission tomography/computed tomography) was done and 14 out of 18 were positive. Treatment included empiric radioactive iodine therapy-16, external beam radiation therapy (EBRT)-7, and lymph node dissection (LND)-10. A favorable outcome was seen in 36 patients and unfavorable in 28. Distant metastases were associated with unfavorable outcome and poor survival. Progression-free survival was significantly better in the Tg group of <10 at the time of TENIS (111 months) compared to the Tg group >10 (72 months). Tg level dropped spontaneously in nearly half the patients, especially if levels were <10 and more so among the low-risk category. Distant metastasis was predictive of unfavorable outcomes. Along with Tg level, the ATA risk category might help to predict clinical course and reduce unnecessary expensive imaging in resource-poor settings.
Fixed 30 mCi (1110 MBq) 131I-iodine therapy in autonomously functioning nodules: Single toxic nodule as a predictive factor of success
Authors: Pereira Lívia , Riguetto Cinthia , Neto Arnaldo , Tambascia Marcos , Ramos Celso , Zantut-Wittmann Denise 
Published: November 2021

AbstractAims: The aim of this study is to evaluate the efficacy of a fixed 30 mCi (1110 MBq) 131I-iodine dose for the treatment of hyperthyroidism due to uninodular or multinodular toxic goiter and identify predictors of success. Materials and Methods: Fifty-nine patients diagnosed with nonautoimmune toxic goiter were treated with a fixed 30 mCi dose of 131I-iodine and were followed at a tertiary service between 2000 and 2016. The therapy was considered successful if the patient reached euthyroidism or hypothyroidism without needing an extra 131I-iodine dose or antithyroid drugs for at least 1 year after the radioiodine therapy (RIT). Results: Patients with a single toxic nodule were younger at diagnosis (52 vs. 63 years; P = 0.007), presented a shorter disease duration until RIT (2 vs. 3.5 years; P = 0.007), smaller total thyroid volume (20 vs. 82 cm3; P = 0.044), and lower pre-RIT thyroid uptake (P = 0.043) than patients with multinodular goiter. No significant difference was seen with antithyroid drug use, thyroid-stimulating hormone and free thyroxine level, and follow-up after RIT. After RIT, 47 patients (79.66%) met the success criteria, and 12 (20.33%) remained hyperthyroid. Among the success group, 32 (68.08%) reached euthyroidism, while 31.92% developed hypothyroidism after 1 year. Patients with single toxic nodules who achieved success after RIT presented smaller nodules (2.8 vs. 5.75 cm; P = 0.043), while the pre-RIT thyroid uptake was higher among patients with multinodular toxic goiter who achieved success after RIT (5.5% vs. 1.5%; P = 0.007). A higher success rate was observed among patients with a single toxic nodule than those with a toxic multinodular goiter (92.3% vs. 55%; P = 0.001), and a single toxic nodule presentation was found to be an independent predictor of success (P = 0.009). Conclusions: The fixed 30 mCi 131I-iodine dose was particularly effective in the group of patients with single autonomously functioning nodule rather than the group with multiple nodules. A single toxic nodule was an independent predictor of treatment success.
Utility of different positron emission tomography/computed tomography tracers in the evaluation of incidentally detected dual malignancies: An experience from a tertiary care center
Authors: Kumar Ram , Gupta Nitin , Verma Ritu , Belho Ethel 
Published: November 2021

AbstractMultiple primary malignancies in a cancer patient are not a rare occurrence. The most common presentation of multiple primary malignancies is dual malignancies. The usefulness of different positron emission tomography (PET)/computed tomography (CT) tracers in the evaluation of dual synchronous primary malignancies is not well documented. Here, we present a case series, where two patients, referred for PET/CT, after being diagnosed with one primary malignancy were found to be having a second primary malignancy, diagnosed incidentally in PET/CT, further validated by PET/CT with another tracer.
Technetium-99m methylene diphosphonate bone scan in evaluation of insufficiency fractures – A pictorial assay and experience from South India
Authors: Srivastava Madhur , Pagala Ram , Kendarla Vinodh , Nallapareddy Kavitha 
Published: November 2021

AbstractInsufficiency fractures (IFs) can be challenging to diagnose due to varied presentations, and sometimes, it changes the course of treatment, as in cancer patients in whom it has to be differentiated with metastatic disease. We present the role of Technetium 99m methylene diphosphonate (99mTc-MDP) bone scan, which is a low-cost, simple to perform, whole body diagnostic investigation in the diagnosis of IFs. This is a retrospective analysis of all patients who underwent a 99mTc-MDP bone scan in a tertiary care teaching hospital during 2013–2017 and were diagnosed as having an IF on bone scan. The bone scans were performed on a dual-head gamma camera using low-energy high-resolution collimators. Of all the bone scan performed during 2013–2017, a total of 138 patients with a mean age of 57.5 ± 14.7 years were diagnosed as having IFs based on bone scan and final clinical diagnosis. Among them, the most common complaint was regional bony pain in 62% of patients, while the most common cause was osteoporosis in 47% of patients, both postmenopausal and senile osteoporosis. In all, 265 sites of fractures were identified with a fracture average of 1.9/patient, the most common site being dorsolumbar vertebrae, followed by ribs and lower limb bones. Many unusual sites were also identified such as talus, sternum, clavicle, and scapula. 99mTc-MDP bone scan, being noninvasive whole-body imaging, is a useful investigation for evaluation of IFs and in correlation with biochemical analysis and other imaging can be used to determine the etiology of IF.
Early diagnosis of focal congenital hyperinsulinism: A fluorine-18-labeled l-dihydroxyphenylalanine positron emission tomography/computed tomography study
Authors: Burroni Luca , Palucci Andrea , Biscontini Giuseppina , Cherubini Valentino 
Published: November 2021

AbstractCongenital hyperinsulinism (CHI) is responsible for hyperinsulinemic hypoglycemia which needs aggressive treatment in order to prevent neurological damages. Recent advances in genetics have linked CHI to mutations in many different genes that play a key role in regulating insulin secretion from pancreatic β-cells. Furthermore, histopathological lesions, diffuse and focal, have been associated with these different genetic alterations. This short manuscript describes how the advent of fluorine-18-labeled L-dihydroxyphenylalanine-positron emission tomography/computed tomography (18F-DOPA-PET/CT) scanning has changed the management of patients with CHI. 18F-DOPA PET/CT imaging differentiates focal from diffuse disease and is 100% accurate in localizing the focal lesion. In these patients, the lesion can be surgically removed allowing complete resolution of clinical alterations. We report a case in which clinical experience together with rapid genetic analysis and imaging with 18F-DOPA-PET/CT, were able to guide the correct clinical management of this condition. We confirm that advances in molecular genetics, imaging methods (18F-DOPA PET-CT), medical therapy, and surgical approach have completely changed the management and improved the outcome of these children.
18FDG PET-CT in sporadic Creutzfeldt-Jakob disease, correlated with MRI and histology
Authors: Morley Nicholas , Hofer Monika , Wilkinson Philip , Bradley Kevin 
Published: November 2021

AbstractWe present a case of sporadic Creutzfeldt–Jakob disease with profoundly abnormal 18fluoro-deoxy-glucose positron emission tomography with computed tomography (FDG PET-CT) at an early stage, and correlate this with the clear findings at magnetic resonance imaging and also postmortem histology. Prion diseases are rare but important causes of cognitive impairment. The role of FDG PET-CT is discussed, along with other investigations such as electroencephalography and cerebro-spinal fluid analyses.