bluuebunny/crossref_metadata_2025_split huggingface dataset:
Heterogeneous material properties—as inferred from seismic attenuation—influenced multiple fault rupture and ductile creep of the KaikouraMw 7.8 earthquake, New Zealand
Authors: Eberhart-Phillips Donna , Ellis Susan , Lanza Federica , Bannister Stephen 
Published: July 2021

SUMMARYThe 2016 Mw 7.8 Kaikoura, New Zealand, earthquake occurred along the eastern margin of the transition region between active subduction in the North Island and oblique collision in the South Island. To infer crustal properties, we imaged Q (1/seismic attenuation) by combining selected M &gt; 3.5 aftershocks with data from previous Q models. For 158 distributed aftershocks, we fit spectral decay on temporary stations and all Geonet stations, providing 6194 t*p and 19 497 t*s. Considering the varied rheology and faults, we also used 2.5-D numerical models to study ductile strain development. The complex earthquake ruptured an ∼180-km-long zone of multiple faults, which involved jumping around the complicated eastern end of the Hope fault, without significant slip on the Hope fault. The Qs and Qp results show features in the upper and lower crust which correlate to the distribution and types of fault rupture. This earthquake involved numerous faults over a region of greywacke crust, where the underlying high Q Cretaceous slab is about 30-km depth. It initiated with ∼5-m slip on the Humps fault in a region of background seismicity and low Q lower crust, adjacent to the Hope fault. The central region near Kaikoura shows a high Q crustal block, which appears to have inhibited rupture; as the rupture progressed over several small faults to jump offshore of the apparently strong block. Underlying the Kaikoura greywacke crust, below 20-km depth, there is a 40-km-long region of increased Vp, Qs and gravity, which likely represents an intraplate plutonic complex emplaced into the Hikurangi Plateau, forming an elevated section which influences deformation. In the northern section, in a region with relatively uniform moderate to low Q, the earthquake evolved into the relatively continuous ∼80-km-long major rupture along the Jordan, Kekerengu and Needles faults, with ∼6–20 m dextral slip at depth and surface displacements of ∼10 m dextral and ∼2 m vertical. The northern progression of the rupture stopped when it approached an abrupt change to high Q crust across Cook Strait. At 20–30-km depth northwest of the rupture, deeper zones with low Q are consistent with regions of distributed ductile shear and creep where the observed afterslip may have occurred, where the underlying slab is 25–40 km deep. The numerical model shows that ductile deformation localizes in this area of lower crust above the relatively strong slab, connecting outer faults (Kekerengu) to inland faults (Clarence, Awatere, Wairau), and demonstrates that no subduction thrust is required under the Marlborough region.
Business groups, institutions, and firm performance
Authors: Cainelli Giulio , Ganau Roberto , Giunta Anna 
Published: July 2021

AbstractThe aim of this paper is twofold. First, we analyze whether firms affiliated to national and international business groups outperform independent firms. Second, we investigate whether any potential performance premium associated with national and international business group membership depends on the quality of sub-national, regional institutions. Using data on Italian and Spanish manufacturing firms, we find a short-run growth premium for international business group members—while not for national business group members—with respect to independent firms. We also find that the growth premium associated with international business group membership is detected in low-quality regional institutional environments only.
A review of adaptation options in fisheries management to support resilience and transition under socio-ecological change
Authors: Woods P J , Macdonald J I , Bárðarson H , Bonanomi S , Boonstra W J , Cornell G , Cripps G , Danielsen R , Färber L , Ferreira A S A , Ferguson K , Holma M , Holt R E , Hunter K L , Kokkalis A , Langbehn T J , Ljungström G , Nieminen E , Nordström M C , Oostdijk M , Richter A , Romagnoni G , Sguotti C , Simons A , Shackell N L , Snickars M , Whittington J D , Wootton H , Yletyinen J 
Published: July 2021

Abstract
Social-ecological systems dependent on fisheries must be resilient or adapt to remain viable in the face of change. Here, we identified possible interventions (termed “adaptation options”) from published literature, aimed at supporting social or ecological resilience and/or aiding adaptation to changes induced by environmental or social stressors. Our searches centered on nations/regions across North America, Europe, and the South Pacific, encompassing fisheries literature with and without a climate change focus, to compare how, when, and by whom interventions are currently or potentially implemented. We expected that adaptation options within a climate change context would have a greater focus on enhancing social resilience due to a connection with climate change adaptation assessment methodology. Instead, we found a greater focus on ecological resilience, likely indicating a focus on management adaptation. This pattern, along with the more extensive use of social adaptation options responsively and outside the context of climate change, along with an importance in bottom-up influences in implementing them, suggests a general lack of centralized planning and organization with regards to adaptation of stakeholders. Determining how adaptation options are created, chosen, and implemented is a crucial step within or external to ecosystem-based management, especially if planned stakeholder adaption is the goal.
Deep-sea benthic habitats and the impacts of trawling on them in the offshore Greenland halibut fishery, Davis Strait, west Greenland
Authors: Long Stephen , Blicher Martin E , Hammeken Arboe Nanette , Fuhrmann Mona , Darling Michael , Kemp Kirsty M , Nygaard Rasmus , Zinglersen Karl , Yesson Chris 
Published: July 2021

Abstract
The offshore Greenland halibut (Reinhardtius hippoglossoides) fishery, west Greenland, employs demersal trawl gear at depths of 800–1400 m. In contrast to many deep-sea fisheries, the target stock appears stable and the fishery is of significant economic importance. Recent Marine Stewardship Council certification of this fishery highlighted the paucity of knowledge of benthic habitats and trawling impacts, which this study aimed to address using a towed benthic video sled. The spatially discrete northern and southern areas of the fishery were found to be distinct in terms of the communities present, which non-metric multidimensional scaling suggests is primarily driven by temperature. Extensive physical evidence of trawling was observed. Trawling effort was significantly linked with community composition, with a negative association between trawling effort and abundance of some taxa, including some vulnerable marine ecosystem (VME) indicator species. Three potential VMEs are identified: (i) Flabellum alabastrum cup coral meadows; (ii) a Halipteris finmarchica sea pen field; and (iii) areas exhibiting mixed assemblages of VME indicators. Of immediate conservation concern is a H. finmarchica field, which seems to be at least regionally rare, is situated within the fringes of existing trawling effort and is currently afforded no protection by management measures.
Bringing the Ottoman Order Back into International Relations: A Distinct International Order or Part of an Islamic International Society?
Authors: Balci Ali 
Published: July 2021

AbstractLong neglected in international relations (IRs), the Ottoman Empire is now getting the attention it deserves. Leaving its “Westphalian straitjacket” behind, the discipline has finally taken a keen interest in non-Western and historical cases. However, the discipline has long focused disproportionately on the Chinese tributary system and produced a large body of literature about it. Spruyt's The World Imagined presents two crucial innovations. The book, on the one hand, introduces the “Islamic international society” into the mainstream, and on the other hand, balances the dominance of the Chinese tributary system in the historical IR subfield. When Spruyt's book is read together with Mikhail's God's Shadow and White's Piracy and Law in the Ottoman Mediterranean, it becomes clear that the Ottoman Empire should be treated as a distinct international order. By including another book in the debate (Casale's The Ottoman Age of Exploration), this study aims to problematize “Islamic international society” and introduce the Ottoman Empire as a distinct international order.
Efficacy of a novel antimicrobial hydrogel for eradication of Staphylococcus epidermidis, Staphylococcus aureus and Cutibacterium acnes from preformed biofilm and treatment performance in an in vivo MRSA wound model
Authors: Ronco Troels , Aragao Maria F , Svenningsen Søren , Christensen Jørn B , Permin Anders , Saaby Lasse , Bionda Nina , Lantz Ellen E , Olsen Rikke H 
Published: July 2021

Abstract

Background
Bacterial biofilm formation is a complicating factor in the antimicrobial treatment of bacterial infections.

Objectives
In this study, we assessed the impact of a novel hydrogel with the active antimicrobial compound JBC 1847 on eradication of preformed biofilms of Staphylococcus epidermidis, Cutibacterium acnes and MRSA in vitro, and evaluated the in vivo efficacy of MRSA wound treatment.

Methods
Biofilms were exposed to JBC 1847 for 24 h and subsequently the treatments were neutralized and surviving biofilm-associated bacteria recovered and enumerated. The efficacy of the hydrogel on post-treatment load of MRSA was determined in a murine model of MRSA wound infection, and skin samples of the infected mice were examined histologically to evaluate the degree of healing.

Results
A concentration-dependent eradication of biofilm-embedded bacteria by JBC 1847 was observed for all three pathogens, and the hydrogel caused a greater than four log reduction of cfu in all cases. In the mouse model, treatment with the hydrogel significantly reduced the cfu/mL of MRSA compared with treatment of MRSA-infected wounds with pure hydrogel. Histopathological analysis of the wounds showed that the JBC 1847 treatment group had a lower grade of inflammation, a higher mean score of re-epithelization and higher mean scores of parameters assessing the maturity of the newly formed epidermis, compared with both the fusidic acid 2% and vehicle treatment groups.

Conclusions
The novel hydrogel shows promising results as a candidate for future wound treatment, likely to be highly effective even in the case of biofilm-complicating infected wounds.
Breed and heterotic effects for mature weight in beef cattle
Authors: Zimmermann Madeline J , Kuehn Larry A , Spangler Matthew L , Thallman R Mark , Snelling Warren M , Lewis Ronald M 
Published: July 2021

Abstract
Cow mature weight (MWT) is heritable and affects the costs and efficiency of a breeding operation. Cow weight is also influenced by the environment, and the relationship between the size and profitability of a cow varies depending on production system. Producers, therefore, need tools to incorporate MWT in their selection of cattle breeds and herd replacements. The objective of this study was to estimate breed and heterotic effects for MWT using weight-age data on crossbred cows. Cow’s MWT at 6 yr was predicted from the estimated parameter values—asymptotic weight and maturation constant (k)—from the fit of the Brody function to their individual data. Values were obtained for 5,156 crossbred cows from the U.S. Meat Animal Research Center (USMARC) Germplasm Evaluation Program using 108,957 weight records collected from approximately weaning up to 6 yr of age. The cows were produced from crosses among 18 beef breeds. A bivariate animal model was fitted to the MWT and k obtained for each cow. The fixed effects were birth year-season contemporary group and covariates of direct and maternal breed fractions, direct and maternal heterosis, and age at final weighing. The random effects were direct additive and residual. A maternal additive random effect was also fitted for k. In a separate analysis from that used to estimate breed effects and (co)variances, cow MWT was regressed on sire yearling weight (YWT) Expected Progeny Differences by its addition as a covariate to the animal model fitted for MWT. That regression coefficient was then used to adjust breed solutions for sire selection in the USMARC herd. Direct heterosis was 15.3 ± 2.6 kg for MWT and 0.000118 ± 0.000029 d−1 for k. Maternal heterosis was −5.7 ± 3.0 kg for MWT and 0.000130 ± 0.000035 d−1 for k. Direct additive heritabilities were 0.56 ± 0.03 for MWT and 0.23 ± 0.03 for k. The maternal additive heritability for k was 0.11 ± 0.02. The direct additive correlation between MWT and k was negligible (0.08 ± 0.09). Adjusted for sire sampling, Angus was heaviest at maturity of the breeds compared. Deviations from Angus ranged from −8.9 kg (Charolais) to −136.7 kg (Braunvieh). Ordered by decreasing MWT, the breeds ranked Angus, Charolais, Hereford, Brahman, Salers, Santa Gertrudis, Simmental, Maine Anjou, Limousin, Red Angus, Brangus, Chiangus, Shorthorn, Gelbvieh, Beefmaster, and Braunvieh. These breed effects for MWT can inform breeding programs where cow size is considered a key component of the overall profitability.
Zinc supplementation strategies in feedlot heifers receiving an extended-release implant or an aggressive re-implant program
Authors: Messersmith Elizabeth M , Niedermayer Emma K , Thornton Kara J , Crawford Grant I , Hansen Stephanie L 
Published: July 2021

Abstract
Two hundred eight Angus-crossbred heifers (291 ± 23 kg) from four sources were used in a randomized complete block design. The objective of the study was to determine the effects of implant strategy and Zn supplementation on performance, carcass characteristics, muscle fiber diameter, and mineral status of heifers. Heifers were assigned to a 2 × 2 factorial study for 168 d, and factors included Zn and implant (IMP). Heifers were supplemented Zn (mg/kg dry matter [DM]; ZnSO4) at national (30; NRC) or industry (100; IND) recommendations. Implant strategies (Merck Animal Health, Madison, NJ) included extended-release Revalor-XH on day 0 (REV-XH; 20 mg estradiol + 200 mg trenbolone acetate) containing four uncoated pellets and six coated pellets or the uncoated implant Revalor-200 on day 0 and again on day 91 (REV-200; 20 mg estradiol + 200 mg trenbolone acetate). Heifers were blocked by weight within source to pens of five or six heifers per pen (nine pens per treatment). A corn silage-based diet was fed during the growing period (days 0–55) followed by transition to a corn-based finishing diet. Weights were taken consecutively on days −1/0, 55/56, and 167/168. Liver and muscle from the longissimus thoracis were collected from one heifer per pen on days −5, 14, 105, and 164. Data were analyzed via Mixed Procedure of SAS. Average daily gain (ADG) and liver mineral used Period as the repeated effect. Corresponding to periods of high hormone payout from each implant, days 0–28 and 91–120 ADG were greatest for REV-200, whereas REV-XH numerically peaked during days 56–91 (IMP × Period; P = 0.02). Day 91 IND body weight tended to be heavier (P = 0.06) and day 120 body weight was heavier (P = 0.05) than NRC heifers. No effect of Zn or IMP on final body weight was observed (P ≥ 0.21). Muscle fiber cross-sectional diameter on day 164 was greater (P = 0.05) in IND than NRC. Liver Mn concentrations decreased by day 14 regardless of implant, though days 105 and 164 concentrations were lesser for REV-200 than REV-XH (IMP × Period; P = 0.02). No effects of Zn, IMP, or the interaction were observed for carcass-adjusted gain to feed, days 0–168 DM intake, hot carcass weight, or ribeye area (P ≥ 0.11). The nominal differences in performance between implant strategies suggest that extended-release implants may be an effective implant strategy to replace re-implant programs in heifers, whereas the improved performance of heifers fed IND vs. NRC during times of peak hormone payout suggests a role for Zn in periods of rapid growth.
Genome mining for drug discovery: progress at the front end
Authors: Baltz Richard H 
Published: July 2021

AbstractMicrobial genome mining for drug discovery and development has been accelerating in recent years, driven by technical advancements in genome sequencing, bioinformatics, metabolomics/metabologenomics, and synthetic biology. Microbial genome mining is a multistep process that starts with the sequencing of microbes that encode multiple secondary metabolites and identifying new and novel secondary metabolite biosynthetic gene clusters (BGCs) to pursue. The initial steps in the process are critical for the overall success, and they encompass the most innovative new technologies to revitalize natural product discovery. As microbial genome mining has matured in recent years, unvalidated conjectures about what microbes to pursue, how to identify legitimate secondary metabolite BGCs, and how to sequence DNA to satisfactory levels of completion have been identified. The solutions to correct the misconceptions around these topics are beginning to be implemented.
Nonribosomal peptide synthetases and their biotechnological potential in Penicillium rubens
Authors: Iacovelli Riccardo , Bovenberg Roel A L , Driessen Arnold J M 
Published: July 2021

Abstract
Nonribosomal peptide synthetases (NRPS) are large multimodular enzymes that synthesize a diverse variety of peptides. Many of these are currently used as pharmaceuticals, thanks to their activity as antimicrobials (penicillin, vancomycin, daptomycin, echinocandin), immunosuppressant (cyclosporin) and anticancer compounds (bleomycin). Because of their biotechnological potential, NRPSs have been extensively studied in the past decades. In this review, we provide an overview of the main structural and functional features of these enzymes, and we consider the challenges and prospects of engineering NRPSs for the synthesis of novel compounds. Furthermore, we discuss secondary metabolism and NRP synthesis in the filamentous fungus Penicillium rubens and examine its potential for the production of novel and modified β-lactam antibiotics.
Core and Whole-Body Vibration Exercise Improve Military Foot March Performance in Novice Trainees: A Randomized Controlled Trial
Authors: Lyons Kaitlin D , Parks Aaron G , Dadematthews Oluwagbemiga D , Zandieh Nilophar L , McHenry Paige A , Games Kenneth E , Goodlett Michael D , Murrah William M , Roper Jaimie A , Sefton JoEllen M 
Published: July 2021

ABSTRACTIntroductionThe purpose of the present study was to investigate core exercise training and whole-body vibration (WBV) as a training method to improve performance and recovery from an 8-km military foot march in novice trainees.Materials and MethodsA 3 × 5 repeated measures randomized control trial was used to evaluate the effects of core exercise training and WBV on performance and recovery from an 8-km foot march. Thirty-nine participants were randomized into three groups: core exercise (Ex), WBV with core exercise (WBVEx), and control. Each participant completed two 8-km foot marches (FM1 and FM2) with a 35 pound rucksack, separated by 4 weeks. Participants in the Ex and WBVEx groups completed 3 weeks of core exercise training, three times per week in between FM1 and FM2. Performance time, creatine kinase (CK), and interleukin-6 (IL-6) were measured. The Auburn University Institutional Review Board approved all aspects of this study (protocol number: 19-211 MR 1907).ResultsPerformance time (P &lt; .001) and CK (P = .005) were significantly improved during FM2 as compared to FM1. The Ex (d = −0.295) and WBVEx (d = −0.645) treatments had a large effect on performance time. CK (P &lt; .001) and IL-6 (P &lt; .001) were significantly elevated at the completion of the foot march regardless of group. Only CK remained elevated for 2 days (P &lt; .001) following the foot march.ConclusionsCore exercise training with or without WBV improved 8-km foot march performance time by 5-6 minutes. The improvements are likely because of an increase in trunk stability. Additionally, this study showed that completing two identical foot marches a month apart increases performance and improves recovery.
Correcting correlation functions for redshift-dependent interloper contamination
Authors: Farrow Daniel J , Sánchez Ariel G , Ciardullo Robin , Cooper Erin Mentuch , Davis Dustin , Fabricius Maximilian , Gawiser Eric , Grasshorn Gebhardt Henry S , Gebhardt Karl , Hill Gary J , Jeong Donghui , Komatsu Eiichiro , Landriau Martin , Liu Chenxu , Saito Shun , Snigula Jan , Wold Isak G B 
Published: July 2021

ABSTRACT
The construction of catalogues of a particular type of galaxy can be complicated by interlopers contaminating the sample. In spectroscopic galaxy surveys this can be due to the misclassification of an emission line; for example in the Hobby–Eberly Telescope Dark Energy Experiment (HETDEX) low-redshift [O ii] emitters may make up a few per cent of the observed Ly α emitter (LAE) sample. The presence of contaminants affects the measured correlation functions and power spectra. Previous attempts to deal with this using the cross-correlation function have assumed sources at a fixed redshift, or not modelled evolution within the adopted redshift bins. However, in spectroscopic surveys like HETDEX, where the contamination fraction is likely to be redshift dependent, the observed clustering of misclassified sources will appear to evolve strongly due to projection effects, even if their true clustering does not. We present a practical method for accounting for the presence of contaminants with redshift-dependent contamination fractions and projected clustering. We show using mock catalogues that our method, unlike existing approaches, yields unbiased clustering measurements from the upcoming HETDEX survey in scenarios with redshift-dependent contamination fractions within the redshift bins used. We show our method returns autocorrelation functions with systematic biases much smaller than the statistical noise for samples with at least as high as 7 per cent contamination. We also present and test a method for fitting for the redshift-dependent interloper fraction using the LAE–[O ii] galaxy cross-correlation function, which gives less biased results than assuming a single interloper fraction for the whole sample.