bluuebunny/crossref_metadata_2025_split huggingface dataset:
Malnutrition in Hospitalized Heart Failure Patients with Reduced Ejection Fraction: Potential Association with Allocation of Guideline-Directed Medical Therapies
Authors: Kawakubo Yumiko , Shiraishi Yasuyuki , Kohsaka Shun , Kohno Takashi , Goda Ayumi , Nagatomo Yuji , Nishihata Yosuke , Saji Mike , Takei Makoto , Ikegami Yukinori , Niimi Nozomi , Sandhu Alexander Tarlochan Singh , Nakano Shintaro , Yoshikawa Tsutomu , Fukuda Keiichi 
Published: September 2021

Abstract
Background: Malnutrition is common in patients with heart failure with reduced ejection fraction (HFrEF) and may influence the long-term prognosis and allocation of guideline-directed medical therapy (GDMT).Methods and Results: We reviewed 1,231 consecutive patient-level records from a multicenter Japanese registry of hospitalized HFrEF patients. Nutritional status was assessed using the geriatric nutritional risk index (GNRI). GDMTs were categorized based on the use of beta-blockers, renin-angiotensin system inhibitors, and mineralocorticoid receptor antagonists. The composite outcome of all-cause death and HF rehospitalization was assessed. The mean age was 72.0±14.2 years and 42.6% patients were malnourished (GNRI<92). At discharge, 43.6% and 33.4% of patients were receiving two (double therapy) and three (triple therapy) GDMT agents, respectively. Malnourished patients had lower rates of GDMT use. The standardized GNRI score was independently associated with the occurrence of adverse events (hazard ratio [HR]: 0.88, 95% confidence interval [CI]: 0.79–0.98; p=0.020). Regardless of the GNRI score, lower risk of adverse events was observed with triple therapy (HR: 0.44, 95% CI: 0.29–0.66; p<0.001) or double therapy (HR: 0.44, 95% CI: 0.29–0.66; p<0.001).Conclusion: Malnutrition assessed by GNRI score predicts long-term adverse outcomes among hospitalized HFrEF patients. However, its prognosis may be modified with GDMT.
Applying Behaviour Change Models to Policymaking: Development and Validation of the Policymakers’ Information Use Questionnaire (POLIQ)
Authors: Shikako-Thomas Keiko , Sherif Reem El , Cardoso Roberta , Zhang Hao , Lai Jonathan , Mogo Ebele , Schuster Tibor 
Published: September 2021

Abstract
BackgroundThe purpose of this study was to develop and validate the Policymakers’ Information Use Questionnaire (POLIQ) to capture the intention of individuals in decision-making position, such as health policymakers, to act on research-based evidence, in order to inform theory and the application of behaviour change models to decision-making. MethodsThe development and validation comprised three steps: item generation, qualitative face validation, and factorial construct validation. Confirmatory factor analysis was applied to estimate item-domain correlations for five pre-defined constructs relating to content, beliefs, behaviour, control and intent. Cronbach’s alpha coefficient was calculated to assess overall consistency of questionnaire items with the pre-defined constructs. Participants in the item generation and face validation were health and policy researchers and two former decision-makers (former assistant deputy ministries) from Canadian provincial level. Participants in the construct validation were 39 Canadian decision-makers at various positions of municipal, provincial, and federal jurisdiction who participated in a series of policy dialogues focused on childhood disability research. ResultsInternal consistency of items belonging to the respective questionnaire domains was moderate to high with estimated Cronbach’s α values ranging from 0.67 to 0.84. Estimated item-domain correlations indicated moderate to high measurement performance for the domains norm, control and beliefs, whereas weak to moderate correlations resulted for the constructs content and intent. Estimate imprecisions of factor loadings (95% confidence interval widths) were considerable for the questionnaire domains content and intent. ConclusionThe study findings provide initial evidence on face validity and appropriate measurement properties of the POLIQ based on a convenient sample of decision-makers in social and health policy. Larger validation studies in relevant populations are needed to further establish psychometric properties and utility of the POLIQ.
Socioeconomic Status and Metabolic Syndrome in Southwest Iran: Results from Hoveyzeh Cohort Study(HCS)
Authors: Saki Nader , Hashemi Seyed Jalal , Hosseini Seyed Ahmad , Rahimi Zahra , Rahim Fakher , Cheraghian Bahman 
Published: September 2021

Abstract
BackgroundSocioeconomic status (SES) is a strong predictor of morbidity and premature mortality, especially non-communicable diseases (NCDs). However, the effect of these factors on Metabolic Syndrome (MetS) is not yet clear. This study is to assess the relationship between socioeconomic indicators and MetS.MethodsIn this prospective cohort study, 10009 people aged 35-70 years enrolled from May 2016 to August 2018. MetS was determined based on the standard national cholesterol education program (NCEP) - adult treatment panel III (ATP III) or NCEP-ATP III criteria. Demographics and socioeconomic data were gathered face to face by trained interviews. Also, lab, anthropometrics, and blood pressure measurements were assayed for participants. Logistic regression was used to estimate the association between SES and MetS, with adjustment of potential confounding variables. ResultsThe overall prevalence of MetS in participants was 39.1%. The crude odds ratios for all the assessed variables were statistically significant (p<0.05). After adjustment for age, sex, physical activity, smoking, and alcohol use as potential confounders, the results indicated significant direct independent associations between skill level (p=0.006) and Townsend index (p=0.002) with MetS, while no significant associations were seen between educational level and wealth status with MetS. ConclusionThe results of our study showed that SES is related to MetS. Among four assessed SES indicators, skilled levels and Townsend score had a stronger association with MetS. We recommend considering people’s SES when interventional programs are planning and conducting on MetS in each community.
Associative and Dissociative Adsorption of N2O Molecule Over C24 Fullerene Doped With V, Mn, Ru, Pd and Rh: A DFT Investigation
Authors: DERDARE Meryem , BOUDJAHEM ABDELGHANI 
Published: September 2021

Abstract
DFT calculations using the PBE-D3 level of theory were conducted on the C24 and MC23 (M = V, Mn, Ru, Pd, Rh and Au) clusters in order to determine their stability and electronic and magnetic properties. The interaction of the N2O molecule with the above clusters has also been examined in order to assess their adsorption and catalytic properties. The results show that the reactivity of the C24 fullerene was greatly improved after doping with a TM atom, and the metal atom which was replaced the carbon atom in the pure C24 fullerene is considered as the most favorable site to adsorb and dissociate the N2O molecule. The molecular adsorption of the N2O on the surface of the MC23 clusters from its oxygen atom was found to be less energetically favorable than by nitrogen atom, and the calculated adsorption energies (Eads) are in the range of - 6.5 to - 24.7 kcal mol-1. The N2O adsorption on the metal site of the clusters could also lead to the dissociation of the N2O into O* and N2 molecule with adsorption energies which vary from - 2.3 to - 86.8 kcal mol-1. The mechanism of the N2O dissociation on the clusters surface was studied, and the activation energies for each system were calculated in order to find the most catalytically active clusters in the N2O decomposition. The results indicate that the activation energies of the VC23 and MnC23 clusters are much lower than those obtained for the other clusters, reflecting high catalytic activity of the two clusters in the N2O decomposition reaction compared to the other studied clusters. The values of Eac of the reaction over the VC23 and MnC23 cluster are 9.3 and 7.9 kcal mol-1, respectively, indicating that both clusters could be employed as greatly active and efficient nanocatalysts for the N2O decomposition reaction.
Hydrodynamics of Regional and Seasonal Variations in Congo Basin Precipitation
Authors: Cook Kerry H , Vizy Edward K. 
Published: September 2021

Abstract
The processes that determine the seasonality of precipitation in the Congo Basin are examined using the atmospheric column moisture budget. Studying the fundamental determinants of Congo Basin precipitation seasonality supports process-based studies of variations on all time scales, including those associated with greenhouse gas-induced global warming. Precipitation distributions produced by the ERA5 reanalysis provide sufficient accuracy for this analysis, which requires a consistent dataset to relate the atmospheric dynamics and moisture distribution to the precipitation field. The Northern and Southern Hemisphere regions of the Congo Basin are examined separately to avoid the misconception that Congo Basin rainfall is primarily bimodal. While evapotranspiration is indispensable for providing moisture to the atmospheric column to support precipitation in the Congo Basin, its seasonal variations are small and it does not drive precipitation seasonality. During the equinoctial seasons, precipitation is primarily supported by meridional wind convergence in the moist environment in the 800 hPa to 500 hPa layer where moist air flows into the equatorial trough. Boreal fall rains are stronger than boreal spring rains in both hemispheres because low-level moisture divergence develops in boreal spring in association with the developing Saharan thermal low. The moisture convergence term also dominates the moisture budget during the summer season in both hemispheres, with meridional convergence in the 850-600 hPa layer as cross-equatorial flow interacts with the cyclonic flow about the Angola and Sahara thermal lows. Winter precipitation is low because of dry air advection from the winter hemisphere subtropical highs over the continent.
A Practical Strategy of Controlled Monopolar Cautery With/Without Oversewing for Staple Line Bleeding in Bariatric Surgery: A Single Center Experience
Authors: Hsu Fang-Chin , Hsu Hai-Ning , Pan Hsin-Mei , Hung Wan-Ting , Liao Guo-Shiou , Chen Teng-Wei , Chan De-Chuan , Hsu Kuo-Feng 
Published: September 2021

Abstract
Introduction

In laparoscopic bariatric surgery, stapling devices are essential for creating a gastric tube or gastric pouch. Staple line bleeding (SLB) is an important issue, but the effect of monopolar cautery for SLB control is unclear. This study aimed to evaluate the outcomes of controlled monopolar cautery with/without oversewing for SLB control during bariatric surgery.
Materials and Methods

From January 2019 to May 2021, 66 patients underwent bariatric surgery with controlled monopolar cautery with/without oversewing for SLB control. Patient demographics and intraoperative and postoperative outcomes were analyzed.
Results

This study enrolled 35 women and 31 men (mean age: 38.1 years; mean body mass index: 39.8 kg/m2). All patients had varying degrees of SLB. Controlled monopolar cautery was applied to 63 patients with ≤6 bleeding sites. Only two patients needed further partial oversewing of the bleeding sites after controlled monopolar cautery failed to achieve hemostasis. Initially, three patients had more than six bleeding sites, and thus complete oversewing was performed to achieve successful hemostasis. There was no intraabdominal or gastrointestinal bleeding. There were one gastric stricture, one anastomotic leakage, and one staple line leakage.
Conclusions

The strategy of controlled monopolar cautery with/without oversewing is a simple, practical, inexpensive, and safe method for SLB control during bariatric surgery.
Exploration of Evaluation Index for Obstetric Anesthesiologists Training in China Using Modified Delphi Method, Experiences From Pilot Project of PKUHSC
Authors: Zhang Xiaoqing , Zhou Yang , Zeng Hong , Li Min , Wang Jun , Wu Changyi , Guo Xiangyang , Xu Mao 
Published: September 2021

Abstract
BackgroundWith the gruadual liberation of fertility policy and the increased number of pregnant women at high-risk in China, a large number of obstetric anesthesiologists (OA) with competency were urgently demanded. In order to establish a replicable and standardized training system for OA specialists, Peking University Health Science Center, one of the first ratified specialists training centers in China, initiated this explorative project. As this is a continuous improving process, the final evaluation index has not been formulated. MethodA working group was set up to devise survey instrument and the initial index draft. We initiated a nation-wide questionnaire pooling opinions of 40 experts from Youth committee of China Anesthesiology Association to construct the evaluation index based on modified Delphi method to reach a consensus. Experts’ demographic information, enthusiasm, authority, and agreement consensus were surgeyed. The final evaluation index would be constructed based on experts’ opinion.ResultsData were collected and analyzed for stability of the experts’ enthusiasm (97.5% and 87.2%, respectively), authority (0.91 ± 0.07 and 0.90 ± 0.13 for the respective two rounds), and agreement consensus (16.7% and 1.3% respectively; Kendall coefficient were 0.26 p = 0.415 and 0.147 p = 0.000, respectively). After two rounds of the survey, the evaluation standard was achieved with 2 items deleted, 5 items added, and 11 major revisions according to experts’ opinion. Revisions mainly focused on clinical practical ability (72%) and the research ability (28%).ConclusionThe final evaluation index was constructed consisting 3 categories (practice ability, non-technical skills, and teaching and research capabilities) with 5 primary and 14 secondary evaluation standards which further divided into 51 items. We hope it could be widely adopted as a standardized evaluation reference for obstetric anesthesiologists training.
Efecto del acceso al tratamiento de la periodontitis sobre la calidad de vida relacionada con la salud bucal
Authors: De La Hoz-Perafán Renata , Loaiza-Echeverri Erika , Arroyave Ivan 
Published: September 2021

La calidad de vida relacionada con la salud oral puede ser influenciada por la periodontitis, una enfermedad inflamatoria que provoca pérdida dental y afecta la integridad y funcionalidad de la cavidad bucal; su condición más severa se presenta en 11,2% de la población mundial. En Colombia, su tratamiento no está cubierto por el Plan de Beneficios en Salud, la presencia de barreras de acceso se asocia con estrés y depresión afectando negativamente la calidad de vida. El objetivo de este estudio fue determinar el efecto del acceso al tratamiento de la periodontitis sobre la calidad de vida relacionada con la salud bucal. Se utilizó el diseño de seguimiento a una cohorte, por censo se reclutaron 149 participantes con periodontitis. Se dividieron entre quienes lograron o no acceder al tratamiento, se midió calidad de vida al inicio y al final del seguimiento. Se encontró asociación entre la calidad de vida relacionada con salud bucal con las variables sexo y uso de prótesis dental. La ausencia del tratamiento especializado de la enfermedad no afecta la calidad de vida porque los usuarios del centro de salud no perciben las barreras de acceso administrativas y organizacionales.
Parálisis criptogénica el tercer par craneal. Reporte de caso
Authors: Díaz-Vallejo Jhony Alejandro , Bastidas-Acosta José Manuel , Gómez-Bastidas Luna Valeria , Martínez-Muñoz Diana Lorena 
Published: September 2021

El nervio motor ocular común o tercer par craneal tiene su origen en el núcleo oculomotor en el mesencéfalo. Emerge de allí y se incorpora en la órbita por medio de la fisura orbitaria superior inervando los músculos elevadores del párpado superior, recto superior, recto medial, recto inferior y oblicuo inferior. Su afectación en pediatría es poco frecuente y suele ser ocasionada por causas congénitas, traumáticas, infecciosas, tumorales, vasculares, tóxicas y desmielinizantes. El propósito es reportar e informar sobre caso de paciente con el diagnóstico de una oftalmoplejía aguda dolorosa del tercer par craneal izquierdo. Se presentó el caso de una paciente femenina de 5 años de edad con el diagnóstico de una oftalmoplejía aguda dolorosa del tercer par craneal izquierdo, de etiología desconocida. Todas las pruebas complementarias fueron normales. Fue manejada con rehabilitación ocular y resolución espontanea sin recurrencias. Este nervio puede presentar una parálisis completa o una parálisis parcial o también llamada incompleta, las parálisis pediátricas del nervio oculomotor son trastornos poco frecuentes, con diferentes mecanismos etiológicos, que difieren de los casos en adultos. Su tratamiento y pronóstico dependen de la etiología, los cuales pueden ser variados.
Psoriatic Arthritis and Risk of Vertebral Fracture: A Systematic Review and Meta-Analysis
Authors: Charoenngam Nipith , Ponvilawan Ben , Thongpiya Jerapas , Yingchoncharoen Pitchaporn , Ungprasert Patompong 
Published: September 2021

Objective:
This study was conducted in order to determine the association between psoriatic
arthritis and the risk of vertebral fracture by pooling the evidence from previous studies.

Methods:
Potentially eligible studies were identified from MEDLINE and EMBASE databases
from inception to March 2020 using a search strategy that comprised of terms “Psoriatic Arthritis”
and “Vertebral Fracture”. Studies were eligible for the meta-analysis if they were cohort studies
that included psoriatic arthritis and individuals without psoriasis and followed them for incident
vertebral fracture. Studies were also required to report standardized incidence ration, hazard risk ratio
or relative risk with related 95% confidence intervals (CI) comparing the incidence of vertebral
fracture between the two cohorts. The retrieved point estimates with standard errors from each
study were pooled into the final result by the random-effect model and generic inverse variance
method.

Results:
A total of 26,090 articles were identified. After two rounds of independent review by
three investigators, we included five cohort studies that met the eligibility criteria in the meta-analysis.
PsA is significantly associated with VF with a pooled odds ratio of 2.09 (95% CI, 1.11 – 3.96;
I2 70%). The funnel plot was fairly asymmetric, thus the publication bias in favor of studies may
present.

Conclusions:
This systematic review and meta-analysis indicates that psoriatic arthritis patients
have a significantly elevated risk of developing a vertebral fracture.
Complications of Paget Bone Disease: A Study of 69 Patients
Authors: Miladi Saoussen , Rouached Leila , Maatallah Kaouther , Rahmouni Safa , Fazaa Alia , Sellami Meriem , Ferjani Hanen , Kaffel Dhia , Hamdi Wafa , Abdelghani Kawther Ben , Laatar Ahmed 
Published: September 2021

Introduction:
Paget bone disease (PBD) is characterized by a disorder in the bone remodeling
activity at sites of involvement. This can produce dramatic alterations of local bone architecture
and causes most of the complications. We aimed to focus on the characteristics of complications
of PDB among hospitalized patients.

Material and Methods:
A retrospective study was conducted, on PBD patients hospitalized in two
rheumatology centers from 1994 to 2019. Characteristics of the PBD complications were studied.

Results:
Sixty-nine patients were collected with a sex ratio of 0.76 and a mean age of 75.4±6.4
years [43-101]. The diagnosis of PBD was established in the average age of 64.2±11.5 years. The
primary reason for consultation was pain (78.3%). The PBD was localized in the pelvis (58%), lower
limb (42%), spine (36.2%), skull (23.2%) and upper limb (5.8%). It was polyostotic in 44.9% of
cases. Dosage of ALP was 324 [68-8390].

:
The PDB complication rate was 52.2% and it decreased over time. The main complication was osteoarthritis
(23.2%), followed by deafness (17.4%), fracture (15.9%), hydrocephalus (7.2%), neurological
disease (7.2%) and osteosarcoma (1.4%). The presence of complications was significantly
associated with the polyostotic form (p=0.01), the skull localization (p=0.04), an increased ALP
(p=0.02).

Conclusion:
According to our study, the incidence rate of PBD among hospitalized cases is higher
among elderly women and decreases over time. Complications related to PDB are frequent (52%).
It concerns patients with a polyostotic form, skull localization and high ALP.
Application Of Seeding Crystallization as a Pre-Treatment Stage for The Reduction of Scaling Tendency of Seawater Feed to Thermal Desalination Units
Authors: Al-Amaireh Mazen N. 
Published: September 2021

Objective:
The fouling inhibition in seawater desalination and scale control using crystallization with calcite seeds is evaluated experimentally in this study.

Methods:
The growth kinetic parameters are determined experimentally, correlated and discussed at different operating conditions. Supersaturation levels represent driving force behind the growth of crystals, which is influenced directly by seawater pH values and temperatures.

Results:

Results indicate that the initial pH value of seawater must be controlled to be in the range (8-9) and calcite seeds will not have the potential to start the growth process in seawater at the normal pH (7.36). The growth kinetic parameters are determined from the measured desupersaturation curves.

Conclusion:
It is found that the growth process of calcite is controlled by the surface integration step. The growth rate of calcite increases with increasing temperature and seeding ratio (up to 1 g/L), while it decreases with increasing the salinity of seawater.
ANALISIS SIYASAH AL-QADHAIYYAH TERHADAP PUTUSAN MAHKAMAH AGUNG NOMOR 39 P/HUM/2018 TENTANG UJI MATERIL PERATURAN GUBERNUR ACEH NOMOR 5/2018
Authors: Syuhada Syuhada , Yuhermansyah Edi , Yuranisa Ulfa 
Published: September 2021

AbstrakTulisan ini hendak mengkaji Putusan Mahkamah Agung Nomor 39 P/HUM/2018 yaitu tentang hak uji materil Peraturan Gubernur Aceh Nomor 5/2018 tentang Hukum Acara Jinayat. Putusan ini berhubungan dengan permohonan uji materil pemohon menyangkut Pasal 30 Pergub yang menyatakan bahwa pencambukan dilakukan di tempat terbuka di Lembaga Pemasyarakatan, atau Rumah Tahanan, ataupun Cabang Rumah Tahanan. Intinya, MA tidak menerima permohonan dari pemohon. Jadi yang menjadi permasalahan ialah bagaimana pertimbangan Hakim MA dalam putusan No 39 P/HUM/2018 terkait penolakan permohonan pengujian Pasal 30 Peraturan Gubernur Aceh Nomor 05 Tahun 2018, dan bagaimana analisis siyasah al-qada’iyah terhadap putusan hakim MA tersebut. Hasil analisis bahwa pertimbangan Hakim MA dalam perkara putusan Nomor 39 P/HUM/2018 tentang penolakan permohonan pengujian Pasal 30 Peraturan Gubernur Aceh Nomor 05 Tahun 2018 adalah mengacu pada legal standing pemohon. Menurut MA, para pemohon sama sekali tidak mempunyai legal standing karena ketentuan Pasal 31 ayat (2) UU Nomor 3 Tahun 2009 tentang MA tidak terpenuhi. Pemohon berada pada posisi yang tidak tepat dan tidak mempunyai legal standing. Pihak pemohon tidak mampu membuktikan kerugian haknya atas diberlakukannya Pergub No: 5/2018. Putusan hakim MA No. 39 P/HUM/2018 sudah sesuai dengan tinjauan siyasah al-qadha’iyyah. Hakim Agung memiliki hak untuk menolak, menerima, atau membatalkan peraturan yang telah dibuat oleh pemerintah melalui pengujian pasal-pasal dengan berdasarkan pada alasan dan dalil yang jelas. MA dalam telah sangat jelas dan tegas menyatakan pertimbangannya dalam menolak permohonan tersebut. Penolakan tersebut sesuai dengan kaidah-kaidah fikih, mengharuskan satu keputusan harus disertakan dengan dalil-dalil (al-dalil) tertentu. Putusan hakim agung juga ditetapkan berdasarkan pertimbangan kemaslahatan. Kata Kunci: Siyasah Al-Qadhaiyyah, Putusan, Mahkamah Agung.