bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chemotactic responses of Brugia pahangi infective third-stage larvae to tris(hydroxymethyl)aminomethane-related compounds and amino acids
Authors: Mitsui Y. , Miura M. , Kato K. , Aoki Y. 
Published: December 2021

Abstract
Since the exogenous compound tris(hydroxymethyl)aminomethane (Tris) showed a potent chemoattractant activity for Brugia pahangi infective third-stage larvae (L3), it was assumed that, in natural infection to a host, filarial L3 can be expected to recognize an endogenous Tris-related compound. In addition, a few amino acids have been identified as water-soluble attractants for second-stage juveniles of Meloidogyne incognita, a plant parasitic nematode. Therefore, the present study assesses the in vitro chemotactic responses of B. pahangi L3 to Tris-related compounds and amino acids using an agar-plate assay. Among Tris-related compounds, 2-amino-1,3-propanediol (APD) and 2-amino-2-methyl-1,3-propanediol (AMPD) exhibited a potent chemoattractant activity for filarial L3 at a level similar to Tris. Furthermore, arginine (Arg) was identified as a potent attractant for filarial L3 among amino acids. In addition, filarial L3 were attracted to Arg, APD and AMPD in mild alkaline conditions rather than acidic conditions. The chemoattractant activity of the three compounds for filarial L3 was observed in concentrations between 6.3 and 200 mm. This is the first report to demonstrate that Arg, APD and AMPD are potent chemoattractants for B. pahangi L3. Endogenous Arg and APD, in particular, may be involved in the regulation of the chemotactic behaviour of filarial L3 in the infection to a host. The present results will help to elucidate the mechanism of filarial skin-penetrating invasion of a host.
Effect of a cold event on population and community of pit-inhabiting sea urchins in Western Pacific coasts
Authors: Yamamori Luna , Kato Makoto 
Published: December 2021

AbstractCoastal tide pools in southern Japan are inhabited by the rock-boring sea urchin Echinostrephus molaris, which excavate pits in the substrate. These pits are subsequently used by non-boring sea urchins such as Anthocidaris crassispina and Echinometra sp. B, and the recolonized pits are often inhabited by a commensal limpet-like trochid snail species, Broderipia iridescens. We explored the population and community dynamics of these sea urchins and the limpet-like snail by monitoring occupancy of 512 pits in tide pools in Shirahama, Japan from May 2017–May 2019. Initially, nearly all pits were occupied by any one of the three sea urchin species, but an unusual cold event in February 2018 caused a mass die off of these sea urchins. After this event, occupancy decreased from 99% to 15%, and the tropical species Echinometra sp. B disappeared from the study pools. We observed slow population recovery of E. molaris and A. crassispina, provably via migration of sub-adults from the subtidal zone. Turnover rate of the pit-occupying sea urchin species was <1.0% before the cold event, but drastically increased after the cold event. Population size of the commensal snail decreased along with those of their host, but the rate of commensalism was constant at 50–55% throughout the study period, suggesting that these snails followed their host sea urchins repeating inter-pit migration. Despite mass mortality and slow recovery, the sea urchin density remained high enough to maintain persistent sea urchin barrens throughout the study period.
Enhancing psychological resilience at the cusp of older ages: the role of social networks
Authors: Visaria Abhijit , Malhotra Rahul , Lee June May-Ling , Chan Angelique 
Published: December 2021

AbstractPrior research has established a positive association between social support and psychological resilience. In this study, we seek to examine whether and to what extent aspects of individuals’ social network – specifically size (how many relatives and friends one has) and strength (how often did one communicate with close network members and at the time of important decisions) – are related to greater psychological resilience. We use data pertaining to 1,609 respondents from the Panel on Ageing and Transitions in Health Survey (PATHS), 2016–2017, a national study of 1,654 older midlife adults, aged 50–59, in Singapore. We estimate the relationship between social networks and psychological resilience, using inverse probability weighted regression adjustment to account for the possibility of a selection bias whereby individuals with larger or stronger social networks may be more resilient at the outset. We find that strong social networks are associated with greater psychological resilience among older midlife adults, regardless of the size of the network. Having a large social network is associated with greater resilience only if it is also a strong network. Maintaining stronger, even if small, social networks may enable individuals at the cusp of older ages to be better prepared to deal with stressful life events and challenges associated with older midlife.
Comparison of different predictive models on HFMD based on weather factors in Zibo city, Shandong Province, China
Authors: Liu L. L. , Hu Y. C. , Qi C. , Zhu Y. C. , Li C. Y. , Wang L. , Cui F. , Li X. J. 
Published: December 2021

Abstract
The early identification and prediction of hand-foot-and-mouth disease (HFMD) play an important role in the disease prevention and control. However, suitable models are different in regions due to the differences in geography, social economy factors. We collected data associated with daily reported HFMD cases and weather factors of Zibo city in 2010~2019 and used the generalised additive model (GAM) to evaluate the effects of weather factors on HFMD cases. Then, GAM, support vectors regression (SVR) and random forest regression (RFR) models are used to compare predictive results. The annual average incidence was 129.72/100 000 from 2010 to 2019. Its distribution showed a unimodal trend, with incidence increasing from March, peaking from May to September. Our study revealed the nonlinear relationship between temperature, rainfall and relative humidity and HFMD cases and based on the predictive result, the performances of three models constructed ranked in descending order are: SVR > GAM> RFR, and SVR has the smallest prediction errors. These findings provide quantitative evidence for the prediction of HFMD for special high-risk regions and can help public health agencies implement prevention and control measures in advance.
Determinants of risky sexual behaviour among undergraduate students at the University of Gondar, Northwest Ethiopia
Authors: Tekletsadik Esayas Alemshet , Ayisa Aynalem Adu , Mekonen Enyew Getaneh , Workneh Belayneh Shetie , Ali Mohammed Seid 
Published: December 2021

Abstract
Risky sexual behaviour (RSB) is defined as behaviours leading to sexually transmitted diseases and unintended pregnancies. According to the Joint United Nations Program on HIV/AIDS, HIV infection was very high among adolescents and youths living in sub-Saharan Africa including Ethiopia. This study was aimed to assess the prevalence of RSB and associated factors among undergraduate students at the University of Gondar.
An institution-based cross-sectional study was conducted from June to July 2019 and a simple random sampling technique was employed to select 420 students. Data were collected using a structured self-administered questionnaire, entered into Epi-info version 7.0 and exported to Statistical Package for Social Sciences (SPSS) version 25 for analysis, and presented in frequencies, percentages and tables. Bivariable and multivariable logistic regression analysis were carried out to identify variables having significant association with RSB.
The prevalence of RSB among undergraduate students at the University of Gondar was 44.0%. Age [adjusted odds ratio (AOR): 2.12; 95% confidence interval (CI) (1.19–3.79)], residence [AOR: 2.14; 95% CI (1.22–3.75)], living arrangement [AOR: 9.79; 95% CI (5.34–17.9)], daily religious attendance[AOR: 0.57; 95% CI (0.33–0.99)], drink alcohol [AOR: 9.19; 95% CI (3.74–22.59)] and having information about reproductive health and sexually transmitted diseases [AOR:3.05; 95% CI (1.00–9.27)] were factors significantly associated with RSB.
Nearly half of the respondents engaged in risky sexual activity. This prevalence is high and the students are at high risk of exposure to sexually transmitted diseases that need reproductive health intervention like counselling and discussion. Creating awareness is needed for the students regarding reproductive health and the risk of sexually transmitted diseases. In addition, giving special attention is required for students who use alcohol, who did not live with family and who have urban residence.
Nutrition policies in Germany: a systematic assessment with the Food Environment Policy Index
Authors: von Philipsborn Peter , Geffert Karin , Klinger Carmen , Hebestreit Antje , Stratil Jan , Rehfuess Eva Annette ,   for the PEN Consortium
Published: December 2021

AbstractObjective:To systematically assess Germany’s nutrition policies, to benchmark them against international best practices and to identify priority policy actions to improve population-level nutrition in Germany.Design:We applied the Food Environment Policy Index (Food-EPI), a methodological framework developed by the International Network for Food and Obesity/non-communicable Diseases Research, Monitoring and Action Support (INFORMAS) network. Qualitative content analysis of laws, directives and other documents formed the basis of a multistaged, structured consultation process.Setting:Germany.Participants:The expert consultation process included fifty-five experts from academia, public administration and civil society.Results:Germany lags behind international best practices in several key policy areas. For eighteen policy indicators, the degree of implementation compared with international best practices was rated as very low, for twenty-one as low, for eight as intermediate and for none as high. In particular, indicators on food taxation, regulation of food marketing as well as retail and food service sector policies were rated as very low to low. Identified priority actions included the binding implementation of nutrition standards for schools and kindergartens, a reform of the value added tax on foods and beverages, a sugar-sweetened beverage tax and stricter regulation of food marketing directed at children.Conclusions:The results show that Germany makes insufficient use of the potential of evidence-informed health-promoting nutrition policies. Adopting international best practices in key policy areas could help to reduce the burden of nutrition-related chronic disease and related inequalities in nutrition and health in Germany. Implementation of relevant policies requires political leadership, a broad societal dialogue and evidence-informed advocacy by civil society, including the scientific community.
The effects of supported employment interventions in populations of people with conditions other than severe mental health: a systematic review
Authors: Probyn Katrin , Engedahl Martin Stav , Rajendran Dévan , Pincus Tamar , Naeem Khadija , Mistry Dipesh , Underwood Martin , Froud Robert 
Published: December 2021

Abstract

Aim:
To assess the effectiveness of supported employment interventions for improving competitive employment in populations of people with conditions other than only severe mental illness.

Background:
Supported employment interventions have been extensively tested in severe mental illness populations. These approaches may be beneficial outside of these populations.

Methods:
We searched PubMed, Embase, CINAHL, PsycInfo, Web of Science, Scopus, JSTOR, PEDro, OTSeeker, and NIOSHTIC for trials including unemployed people with any condition and including severe mental illness if combined with other co-morbidities or other specific circumstances (e.g., homelessness). We excluded trials where inclusion was based on severe mental illness alone. Two reviewers independently assessed risk of bias (RoB v2.0) and four reviewers extracted data. We assessed rates of competitive employment as compared to traditional vocational rehabilitation or waiting list/services as usual.

Findings:
Ten randomised controlled trials (913 participants) were included. Supported employment was more effective than control interventions for improving competitive employment in seven trials: in people with affective disorders [risk ratio (RR) 10.61 (1.49, 75.38)]; mental disorders and justice involvement [RR 4.44 (1.36,14.46)]; veterans with posttraumatic stress disorder (PTSD) [RR 2.73 (1.64, 4.54)]; formerly incarcerated veterans [RR 2.17 (1.09, 4.33)]; people receiving methadone treatment [RR 11.5 (1.62, 81.8)]; veterans with spinal cord injury at 12 months [RR 2.46 (1.16, 5.22)] and at 24 months [RR 2.81 (1.98, 7.37)]; and young people not in employment, education, or training [RR 5.90 (1.91–18.19)]. Three trials did not show significant benefits from supported employment: populations of workers with musculoskeletal injuries [RR 1.38 (1.00, 1.89)]; substance abuse [RR 1.85 (0.65, 5.41)]; and formerly homeless people with mental illness [RR 1.55 (0.76, 3.15)]. Supported employment interventions may be beneficial to people from more diverse populations than those with severe mental illness alone. Defining competitive employment and increasing (and standardising) measurement of non-vocational outcomes may help to improve research in this area.
The Role of Physical Parameterization Schemes in Capturing the Characteristics of Extratropical Cyclones Over the South Pacific Ocean
Authors: Gómez Matías , Mäll Martin , Aránguiz Rafael 
Published: December 2021

AbstractThe extratropical cyclone (ETC) of August 2015 in central Chile was investigated using the WRF model to analyze the sensitivity of meteorological variables to different physical parameterization schemes. This study assesses the performance of different physical schemes in the simulation of track, core pressure, mean sea level pressure, wind direction and wind speed associated with ETC over the South Pacific. The analysis uses a total of 36 sensitivity experiments, consisting of: two microphysics schemes; three surface layer and planetary boundary layer; two cumulus schemes; two longwave and shortwave radiation; and Noah for land surface. Sensitivity experiments indicate that the cumulus, planetary boundary layer and surface layer scheme have a fundamental role in the characterization of ETC track and intensity, while the microphysics scheme plays a secondary role in determining these variables. On the other hand, long‐ and shortwave radiation do not have a significant impact. The sensitivity experiments indicate that exp24 provides the best results overall. The results of this work allow the selection time of the different physical schemes to be optimized according to the ETC characteristics that are to be simulated
Prevalence, Distribution, and Genotypes of Adenovirus and Norovirus in the Puzi River and Its Tributaries and the Surrounding Areas in Taiwan
Authors: Nagarajan Viji , Chen Jung‐Sheng , Hsu Bing‐Mu , Hsu Gwo‐Jong , Wang Jiun‐Ling , Hussain Bashir 
Published: December 2021

AbstractThis study investigated the prevalence, distribution, and genotypes of adenoviruses (AdVs) and noroviruses (NoVs) in the Puzi River and surrounding areas in Taiwan. The viruses in the water samples were isolated using the membrane filtration method and the viral nucleic acids were extracted. The RNA of NoVs was reverse‐transcribed into complementary DNA using reverse transcriptase‐polymerase chain reaction. AdVs and NoVs were detected using nested PCR. Genotyping and phylogenetic analyses were performed to identify the various viral genotypes in the water samples. Human adenovirus (HAdVs) and porcine adenovirus (PAdVs) were the predominant genotypes in the water samples. The prevalence of F species HAdVs serotype 41 (79.2%) and C species PAdVs serotype 5 (18.1%) was higher than that of other serotypes. Among NoVs, genogroup GII was more prevalent than GI. In particular, GII.4 (21.2%) and GII.17 (18.2%) were the predominant genotypes, which was consistent with the clinical findings. The prevalence of both AdVs and NoVs was higher in the winter than spring, summer and autumn seasons. AdVs and NoVs detection results were statistically analyzed by investigating their association with water quality indicators. The results revealed that the presence of AdVs was significantly correlated with the heterotrophic bacterial count, total coliform Escherichia coli, turbidity, salinity, and dissolved oxygen. Meanwhile, the presence of NoVs was only significantly correlated with temperature, pH, and dissolved oxygen. Microbial pollution sources may include urban runoff and discharge of water from livestock farms situated near the river and tributaries within this region of Taiwan. Future studies should include comparisons of the presence of AdVs and NoVs in these known pollution sources and water quality monitoring of these watersheds, as this will allow potential identification of pollution sources. Additionally, remediation strategies must be developed to minimize viral contamination in the river ecosystem.
Linking Chemical Heterogeneity to Lithological Heterogeneity of the Samoan Mantle Plume With Fe‐Sr‐Nd‐Pb Isotopes
Authors: Wang Xiao‐Jun , Chen Li‐Hui , Hanyu Takeshi , Shi Jin‐Hua , Zhong Yuan , Kawabata Hiroshi , Miyazaki Takashi , Hirahara Yuka , Takahashi Toshiro , Senda Ryoko , Chang Qing , Vaglarov Bogdan S. , Kimura Jun‐Ichi 
Published: December 2021

AbstractThe Samoan mantle plume is thought to host three isotopically (radiogenic) distinct low‐3He/4He components including EM2 (enriched mantle 2), dilute HIMU (high μ = 238U/204Pb), and a depleted mantle (DM) component, which were sampled by shield‐stage lavas from the Malu, Vai, and Upo trend volcanoes, respectively. However, it is unclear whether the isotopically distinct components are present as different lithologies. Using new Fe–Sr–Nd–Pb isotope data for Tutuila basalts (Samoa), combined with literature data for other Samoan basalts, we attempt to infer the lithological structure of the Samoan plume. The results show that “Malu trend” basalts have heavier Fe isotopic compositions (δ57Fe = 0.15–0.24‰) than “Vai trend” and “Upo trend” basalts. The latter two groups have average δ57Fe of 0.14 ± 0.07‰ (2SD) and 0.11 ± 0.03‰ (2SD), respectively, similar to normal midocean ridge basalts (N‐MORBs, δ57Fe = 0.15 ± 0.05‰, 2SD). The fractional‐crystallization‐corrected δ57Fe values of all shield lavas are positively correlated with (Gd/Yb)N, Pb/Nd and 87Sr/86Sr ratios whereas negatively correlated with Nb/Th and εNd ratios, which cannot be explained by partial melting of a single garnet peridotite but point to heterogeneous source lithologies. The EM2 lavas are characterized with high δ57Fe and (Gd/Yb)N, low Nb/Th, and enriched Sr–Nd isotopic ratios, requiring a pyroxenitic source component with imprints of both recycled terrigenous sediments and oceanic crust. The Vai‐ and Upo‐trend lavas with MORB‐like δ57Fe can be explained by partial melting of peridotitic sources, although different extents of refertilization by recycled crust are essential for generating their distinct radiogenic isotope signatures. These observations highlight the lithological heterogeneity of the Samoan plume and relates the EM2 component with a pyroxenitic lithology.
Data Assimilation of High‐Latitude Electric Fields: Extension of a Multi‐Resolution Gaussian Process Model (Lattice Kriging) to Vector Fields
Authors: Wu Haonan , Lu Xian 
Published: December 2021

AbstractWe develop a new methodology for the multi‐resolution assimilation of electric fields by extending a Gaussian process model (Lattice Kriging) used for scalar field originally to vector field. This method takes the background empirical model as “a priori” knowledge and fuses real observations under the Gaussian process framework. The comparison of assimilated results under two different background models and three different resolutions suggests that (a) the new method significantly reduces fitting errors compared with the global spherical harmonic fitting (SHF) because it uses range‐limited basis functions ideal for the local fitting and (b) the fitting resolution, determined by the number of basis functions, is adjustable and higher resolution leads to smaller errors, indicating that more structures in the data are captured. We also test the sensitivity of the fitting results to the total amount of input data: (a) as the data amount increases, the fitting results deviate from the background model and become more determined by data and (b) the impacts of data can reach remote regions with no data available. The assimilation also better captures short‐period variations in local PFISR measurements than the SHF and maintains a coherent pattern with the surrounding. The multi‐resolution Lattice Kriging is examined via attributing basis functions into multiple levels with different resolutions (fine level is located in the region with observations). Such multi‐resolution fitting has the smallest error and shortest computation time, making the regional high‐resolution modeling efficient. Our method can be modified to achieve the multi‐resolution assimilation for other vector fields from unevenly distributed observations.
Psychological Screening and Consultation in a Pediatric Diabetes Clinic: Medical Providers’ Perspectives
Authors: Brodar Kaitlyn E. , Leite Rafael O. , Marchetti Daniella , Jaramillo Manuela , Davis Eileen , Sanchez Janine , Delamater Alan M. , Saab Patrice G. , La Greca Annette M. 
Published: December 2021

Objective: Psychosocial concerns are common among youth with Type I diabetes; psychosocial screening and integrated care models can address these concerns. Medical providers are key stakeholders, but their perspectives on the role of mental health within pediatric diabetes care represent a gap in the literature. This study aimed to describe pediatric diabetes care providers’ views on the relationship between psychosocial stress and diabetes, their experiences with psychosocial screening and psychological consultation within their clinic, and their suggestions for mental health professionals working with youth who have diabetes. Method: All endocrinologists, fellows, and diabetes educators involved with psychosocial screening and psychology consultations ( N = 7; 71.4% female, 42.9% Hispanic/Latinx White, 28.6% Non-Hispanic/Latinx White, 28.6% Asian) at a single outpatient pediatric diabetes clinic participated in semistructured interviews. Qualitative data were analyzed via thematic content analysis. Results: Providers described a bidirectional relationship between psychosocial stress and diabetes management. They expressed positive views of psychosocial screening and the clinic’s integrated psychology team, which allow them to focus on the medical aspect of care and gain comfort with mental health. Providers offered suggestions to improve coordination and communication with mental health professionals. Conclusions: Pediatric diabetes care providers valued psychosocial screening and benefited from collaboration with the clinic psychology team. Clinics without access to mental health professionals may struggle to sustain screening practices. Eliciting medical providers’ opinions and using other implementation science strategies are important for incorporating psychosocial screening and intervention within pediatric diabetes clinics, especially for clinics with unique models for psychological services. Implications for Impact Statement Medical providers in a pediatric diabetes clinic reported positive views of psychosocial screening and psychology consultations. Interdisciplinary collaboration with mental health professionals may promote medical providers’ comfort, confidence, and competence navigating their patients’ mental health concerns and ultimately improve care for youth with Type I diabetes mellitus. Obtaining medical providers’ perspectives is important for effective implementation of psychosocial screening procedures in diabetes clinics with varying models for access to mental health services.