bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modern Approaches to Analysis of Technical and Tactical Actions of Skilled Volleyball Players
Authors: Oliinyk Iryna , Doroshenko Eduard , Melnyk Mykhaylo , Sushko Ruslana , Tyshchenko Valeria , Shamardin Valerij 
Published: September 2021

Purpose. To develop an algorithm of special analysis for improving the training process, based on the identification of indicators of technical and tactical actions in the competitive activity of skilled volleyball players.
Material and Methods. The study analyzed 2,688 technical and tactical indicators of the competitive activity of 56 players of national volleyball teams which played 6 games in the 2019 CEV Volleyball European Championship, taking into account the athletes’ playing roles, based on the methods of analysis of the competitive activity, analysis of generalization of practical experience, and theoretical modeling.
Results. The study interpreted the total performance indicators of the competitive activity of skilled volleyball players, the indicators of technical and tactical activity in the competitive process, the ratio of performance indicators in skilled volleyball players in position zones.
Conclusions. The modified algorithm of special analysis of indicators of technical and tactical actions has the following structure: analysis of quantitative characteristics of team, group and individual actions in attack and defense; chronological analysis of the competitive activity development in sets; analysis of playing actions in various zones of the court; comparative analysis of quantitative indicators of technical and tactical actions of volleyball players who directly counteract in the match; analysis of critical moments of the game, which is directly related to organizing and holding a particular match; interpretation and qualitative analysis of indicators of technical and tactical actions in a particular match.
Based on the analysis of success and performance indicators of the competitive activity of Ukraine’s national volleyball team in the qualifying tournament of the 2019 European Championship (group F), it can be said that the modified algorithm of special analysis of indicators of technical and tactical actions showed high efficiency.
Surface Electromyography Based Core Muscle Fatigue Analysis During Repetitive Plank Using Multivariate Dimensionality Reduction Methods in Boys Aged 12-14
Authors: Samanta Abir , Mukherjee Sabyasachi 
Published: September 2021

The aims of the study were: 1. To analyse the discriminative power of neuromuscular components for classifying the pre and post muscle fatigued states. 2. To examine whether the modification of neural recruitment strategies become more/less heterogeneous due to fatigue. 3. To research the effect of Erector Spinae (ES) muscle activity collectively with Rectus Abdominis (RA) and External Oblique (EO) muscle activity to identify the reduced spine stability during fatiguing Plank.
Material and methods. Twelve boys (age – 12-14 years, height 148.75 ± 10 cm, body mass 38.9 ± 7.9 kg) participated in the study. Multivariate Discriminant Analysis (DA) and Principal Component Analysis (PCA) were applied to identify the changes in the pattern of the electromyographic signals during muscle fatigue. In DA the Wilks’ lambda, p-value, canonical correlation, classification percentage and structure matrix were used. To evaluate the component validity the standard limit for Kaiser-Meyer-Olkin (KMO) was set at ≥0.529 and the p-value of Bartlett’s test was ≤0.001. The eigenvalues ≥1 were used to determine the number of Principal Components (PCs). The satisfactory percentage of non-redundant residuals were set at ≤50% with standard value >0.05. The absolute value of average communality (x̄ h2) and component loadings were set at ≥0.6, ≥0.4 respectively.
Results. Standardized canonical discriminant analysis showed that pre and post fatigued conditions were significantly different (p = 0.000, Wilks’ lambda = 0.297, χ2 = 24.914, df=3). The structure matrix showed that the parameter that correlated highly with the discriminant function was ES ARV (0.514). The results showed that the classification accuracy was 95.8% between fatigued conditions. In PCA the KMO values were reduced [0.547Pre fatigue vs. 0.264Post fatigue]; the value of Bartlett’s sphericity test was in pre χ2 = 90.72 (p = 0.000) and post fatigue χ2 = 85.32 (p = 0.000); The Promax criterion with Kaiser Normalization was applied because the component rotation was non-orthogonal [Component Correlation Matrix (rCCM) = 0.520 Pre fatigue >0.3Absolute<0.357Post fatigue]. In pre fatigue two PCs (cumulative s2 – 80.159%) and post fatigue three PCs (cumulative s2 – 83.845%) had eigenvalues ≥1. The x̄ h2 increased [0.802 Pre fatigue vs. 0.838 Post fatigue] and the percentage of nonredundant residuals reduced [50% Pre fatigue vs. 44% Post fatigue] from pre to post fatigue.
Conclusions. The variability and heterogeneity increase in the myoelectric signals due to fatigue. The co-activity of antagonist ES muscle is significantly sensitive to identify the deteriorating spine stability during the fatiguing Plank. Highly correlated motor unit recruitment strategies between ES and RA, providing supportive evidence to the concept of shared agonist-antagonist motoneuron pool or “Common Drive” phenomenon during fatigue.
The Effect of Knowledge Level (IQ) and Physical Conditions (Power, Flexibility and Coordination) on Smash Technique Learning Skill in Sepak Takraw
Authors: Jufrianis Jufrianis , Henjilito Raffly , Hernawan Hernawan , Sukiri Sukiri , Sukur Abdul , Abidin Dindin , Karakauki Manil , Syed Ali Syed Kamaruzaman , Pratama Kukuh Wahyudin 
Published: September 2021

Athlete’s knowledge level (IQ) is needed to increase smash technique learning skill in sepak takraw. Besides, physical conditions which consist of power, flexibility and coordination, are also determined athlete’s accomplishment in learning smash technique in sepak takraw.
The study purpose. The aim of this research was to discover the direct influence between knowledge level (IQ) and physical conditions (power, flexibility and coordination) on smash technique learning skill in sepak takraw.
Materials and Methods. The method used in this research was quantitative. Path analysis was conducted to analyze the result. As many as 50 athletes of sepak takraw from capital city of Jakarta were taken as population. Those athletes were also taken as sample by using total sampling. The sample was the athletes who joined the regional and national championship.
Results. Based on the research it was obtained: 1) knowledge level (IQ) affects smash technique learning skill in sepak takraw directly as many as 0.982; 2) physical conditions (power, flexibility and coordination) affect smash technique learning skill in sepak takraw directly as many as 0.845; and 3) overall, knowledge level (IQ) and physical condition (power, flexibility and coordination) affect smash technique learning skill in sepak takraw directly as many as 0.703.
Conclusion. Therefore, it could be concluded that knowledge level (IQ) and physical conditions (power, flexibility and coordination) affect smash technique learning skill in sepak takraw on the athletes of capital city of Jakarta.
The Current Implementation of an Evidence-Based Hamstring Injury Prevention Exercise (Nordic Hamstring Exercise) among Athletes Globally
Authors: Al Attar Wesam Saleh A. 
Published: September 2021

Purpose. The Nordic hamstring exercise (NHE) has been shown to be successful in reducing hamstring muscle injury (HMI), which is one of the most common non-contact injuries of the lower limbs. This is especially pertinent in sports that require acceleration, maximal sprints, and sudden changes in the direction of running and sprinting, such as soccer and rugby. This study aimed to evaluate the awareness, implementation, and opinions of athletes worldwide regarding the effectiveness of NHE in preventing hamstring injury.
Materials and methods. A self-administered questionnaire was distributed to 1500 athletes from different sports. The survey consisted of six questions covering country, gender, type of sport, awareness, implementation, and opinions of athletes worldwide regarding the effectiveness of NHE in preventing hamstring injury. The survey was available in ten different languages.
Results. A total of 1142 male and female athletes from different sports participated in the survey. More than half of the athletes 641 (56%) were aware of NHE, and only 519 (45.4 %) were implementing NHE in their current training routines. Athletes who implemented NHE reported a positive opinion regarding the program’s effectiveness with a score of 8.4 ± 1 out of 10.
Conclusions. Many athletes were aware of NHE and implemented it in their training routine since they found it to be effective in decreasing hamstring injury rates. However, additional work must be done to educate athletes about the importance of implementing this exercise and its effectiveness in preventing hamstring injury.
Neuropsychological features of patients of reproductive age diagnosed with breast cancer at the stage of surgical treatment using xenon-oxygen therapy
Authors: Rozenko D. A. , Shikhlyarova A. I. , Vaschenko L. N. , Popova N. N. , Arapova Yu. Yu. , Ardzha A. Yu. , Korobov A. A. 
Published: September 2021

Purpose of the study. To study functional changes in the neuropsychological status of reproductive age patients with newly diagnosed breast cancer and to assess the possibility of using xenon-oxygen therapy to correct disorders.Patients and methods. This study included 60 reproductive age patients with newly diagnosed breast cancer who were undergoing surgical treatment at the Department of Bone, Skin, Soft Tissue and Breast Tumors of the National Medical Research Centre for Oncology of the Ministry of Health of Russia from 2018 to 2020. The main group included 30 patients with breast cancer diagnosed at the surgical stage of combined treatment, who underwent a rehabilitation course of xenon-oxygen therapy in the early postoperative period. The control group was formed from patients with the same diagnosis, without the use of this therapy. The functional state of the central nervous system in all patients was assessed by the parameters of the electroencephalography (EEG) bioelectrical activity. For the final assessment of the physiological and psychological state of the patients, a standardized questionnaires of the quality of life – ESAS, MOS-SF‑36, were used. Statistical data processing was performed using the Statistica 10 software package. Results. During the study, statistically significant differences were found in the assessment of subjective indicators, so in the group of patients using xenon-oxygen therapy, there was an improvement in well-being by 2.6 times, a decrease in depression by 2.3 times, a decrease in symptoms of nausea by 3 times, anxiety 1.9 times (p < 0.05). Against the background of an improvement in the psychophysiological state, the EEG showed a significant increase in the power of slow delta and theta rhythms, an increase in the power of the alpha rhythm and a decrease in the power of the beta rhythm, while in the patients of the control group only a decrease in the power of the beta rhythm was noted.Conclusion. The early postoperative period in patients with newly diagnosed breast cancer is characterized by the formation of a depressive symptom complex. The use of a course of xenon-oxygen therapy contributes to the normalization of the subjective feeling of physical and psychological health, increasing vital and social activity. Changes in the indicators of brain bioelectric activity and an improvement in psychophysiological state occur against the background of changes in brain activity caused by the normalizing effect of xenon.
On mechanisms of antitumor action of tropolon series compounds
Authors: Zhukova G. V. , Lukbanova E. A. , Protasova T. P. , Zaikina E. V. , Kiblitskaya A. A. 
Published: September 2021

The review provides information on the mechanisms of the antitumor action of natural and synthetic compounds of the tropolone series, obtained over the past 30 years in studies on cell cultures and, to a lesser extent, in in vivo experiments. Interest in this group of substances is due to the urgent need of clinical oncology for drugs that effectively damage malignant cells and, at the same time, are safe for healthy tissues. The processes that realize the effects of colchicine, hinokithiol (ß-tuyaplicin) and some of their derivatives (derivatives of bistropolone, α-substituted tropolones, etc.) have been studied most fully. Herewith, more numerous mechanisms of realization of the antitumor effect of hinokithiol and its derivatives were revealed in comparison with colchicine. In addition to the disruption in the formation of the cell division spindle, shown for colchicine and colchamine, such phenomena as caspase-dependent apoptosis and some other types of apoptosis, autophagy, limitation of mitochondrial metabolism, DNA damage and demethylation, and accelerated aging of malignant cells etc. have been described. The promising properties of 2‑quinolyl 1,3‑tropolone derivatives have been shown, and the relationship of their antitumor effect with the induction of apoptosis and changes in the activity of the ERK signaling pathway in some types of malignant cells have been revealed. The results indicate a multiplicity of possible ways of the influence of tropolones on the state of malignant cells, the conditions for the implementation of ones need to be clarified, especially with a lack of information about in vivo processes.The review includes information from the literature presented in the Scopus, WoS, Pubmed databases. 35 % of articles have been published in the last 5 years.
Difficult cases of differential diagnosis of acute appendicitis
Authors: Otdelnov L. A. , Mastukova A. M. 
Published: September 2021

Despite the results of technological progress in medicine, which has made high-resolution methods of medical imaging available, the problem of differential diagnosis of acute appendicitis does not lose its’ relevance. This can be explained by the fact that the symptoms of acute appendicitis are variable, non-specific, and can mimic other diseases with similar symptoms.Three cases of rare diseases of the gastrointestinal tract that simulates acute appendicitis were presented. Those are primary torsion of the greater omentum with necrosis, caecum cancer with lengthy necrosis in a young patient and Crohn's disease that simulates appendicular infiltrate. All patients underwent surgery. Signs of acute appendicitis were indications for surgery. Laparoscopic resection of greater omentum was performed in the first case. In the second case caecum necrosis with peritonitis was revealed by laparoscopy. Conversion laparoscopy to laparotomy was performed. Caecum necrosis with caecum wall perforation and necrosis of terminal part of the ileum was diagnosed. right hemicolectomy with ileo-transverso anastomosis was carried out. Complicated case of Crohn’s disease was suspected. Nevertheless, the diagnosis of colorectal cancer is established by pathomorphology only. This case is interesting because of rare complication of colon cancer – the caecum and the ileum wall necrosis that was manifestation of the disease. In the third case of Crohn’s disease in a young patient the diagnosis of appendicular infiltrate and surgical policy were wrong. At the first laparotomy by McBurney was performed. A dense infiltrate was found in the right iliac fossa. The intervention was finished by local abdominal package. In the early postoperative period an intestinal fistula was formed. The patient underwent relaparotomy and right hemicolectomy with ileo-transversal anastomosis was carried out. Despite the diagnosis of Crohn's disease was questionable patomorphology and was established after half a year only by colonoscopy. The presented cases illustrate the complexity of acute appendicitis and the importance of modern approaches to diagnosis: irreplaceability of laparoscopy and the feasibility of using diagnostic scales. When the right diagnosis is not clear the intervention might be late for using methods of instrumental diagnostics.
Data analysis of high-throughput sequencing and microarray to identify key signatures of microribonucleic acids in glioblastoma
Authors: Pushkin A. A. , Dzenkova E. A. , Timoshkina N. N. , Gvaldin D. Yu. 
Published: September 2021

Purpose of the study. This research was devoted to study of mRNA and miRNA expression patterns in glioglastomas using The Cancer Genome Atlas (TCGA) data, to search for genetic determinants that determine the prognosis of patient survival and to create of interaction networks for glioblastomas.Materials and methods. Based on the data of the open TCGA database groups of glioblastomas and conventionally normal brain tissue samples were formed. Survival gene and miRNA expression data were extracted for each sample. After the data stratification by groups the differential expression analysis and search the genes affecting patient survival was carried out. The enrichment analysis by functional affiliation and an interactome analysis were performed.Results. A total of 156 glioblastoma samples with mRNA sequencing data, 571 samples with microarray microRNA analysis data, and 15 control samples were analyzed. Networks of mRNA-miRNA interactions were built and expression profiles of genes and miRNAs characteristic of glioblastomas were developed. We have determined the genes which aberrant level is associated with survival and shown the pairwise DEG and DE of microRNA correlations.Conclusion. The microRNA-mRNA regulatory pairs identified for glioblastomas can stimulate the development of new therapeutic approaches based on subtype-specific regulatory mechanisms of oncogenesis.
Breast cancer screening during the adverse COVID-19 epidemiological situation
Authors: Drzhevetskaya K. S. , Korzhenkova G. P. 
Published: September 2021

Purpose of the study. To evaluate the results of breast cancer screening (BC) in the conditions of an unfavorable epidemiological situation COVID‑19 based on the analysis of the BC screening project in the Kaluga Region.Patients and methods. Screening system: creation and implementation in practice of mobile mammography complexes (MMC); training of medical personnel in the method of conducting a standardized mammographic examination (ME); quality control of ME; "Cloud" storage and software development for archiving patients; an independent review of mammograms by certified specialists; expert review of images in case of discrepancies in diagnoses; referral of patients diagnosed with BI-RADS IV and V to the regional oncological dispensary for further examination and treatment. From 04.2018 to 12.2020 patients were examined on MMC according to the BC screening protocol. We examined 47367 patients over the age of 40 years. SD 57.66 ± 8.17 years (38-93). During the COVID‑19 pandemic, imaging of breast diseases must be carried out in compliance with all safety regulations for both personnel and patients. Balancing the need to avoid delays in diagnosing BC while preventing infection requires careful attention to personal protective equipment, handling of diagnostic equipment, diagnostic facilities, and physical distancing and vigilance to maintain these measures.Results. From 07.2020 to 11.2020: a total of 10736 studies have been carried out. In the context of new coronavirus infection, we noted an increased demand among patients wishing to undergo BC screening. The flow of patients over the same period of previous years was less, which indicates the demand and justification for screening mammography and the use of MMC in an unfavorable epidemiological situation. 174 patients received category BI-RADS IV-V and were referred for a follow-up examination and required treatment at an oncological dispensary. In 39 patients (22.4 %), BC was verified, and appropriate treatment was carried out. In 135 cases, benign processes were verified.Conclusion. BC screening should not be stopped against the backdrop of the COVID‑19 epidemic since a delay in BC diagnosis later threatens to reveal more voluminous processes with a worse prognosis for treatment and rehabilitation than timely detected changes in the mammary glands in the early preclinical stages of the disease.
Molecular genetic changes in kidney tissue in patients with COVID-19
Authors: Demyashkin G. A. , Mingazov A. M. , Kaprina E. A. , Shchekin V. I. , Shegay P. V. 
Published: September 2021

Purpose of the study. Assessment of the molecular genetic profile of cytological processes in the kidney tissue of patients with COVID‑19.Material and methods. Kidney fragments from patients with confirmed COVID‑19 (n = 96) were studied by real-time polymerase chain reaction to determine the expression of SARS-CoV‑2 viral RNA and genes encoding protein complexes: ACE‑2 and Furin. Results. In patients affected by COVID‑19, the presence of coronavirus genetic material in kidney tissue was recorded, as well as increased expression of ACE‑2 (7.49 ± 0.27, p < 0.01) and Furin 2.0 times (8.59 ± 0.65, p < 0.01,) compared with the control group (3.9 ± 0.48, p < 0.01 and 4.2 ± 0.8, p < 0.01, respectively), which creates favorable conditions for the invasion of SARS-CoV‑2.Conclusion. According to the results of RT-PCR for SARS-CoV‑2, assessment of the expression of ACE‑2 and Furin, it is possible with a high degree of probability to assert about the viral load and the vulnerability of the kidneys, since these proteins are informative markers of viral damage. Elderly people with increased vulnerability to SARS-CoV‑2.
Optimization of laparoscopic ureteral repair with a buccal graft in case of its extended strictures and obliterations
Authors: Volkov A. A. , Budnik N. V. , Zuban O. N. 
Published: September 2021

Purpose of the study. Currently, laparoscopic technique has become widely used in the treatment of extended strictures and obliterations of the ureter. The use of minimally invasive approaches will also be relevant for such a relatively new operation as buccal ureteroplasty. In the literature, there are isolated publications devoted to this technique. The aim of this study was to study the results of our own experience of laparoscopic ureteral reconstruction using a buccal graft.Patients and methods. We observed 5 patients – 2 men and 3 women, at the age of 30–62 years. All patients have already been operated on the urinary tract, of these, in four patients, the urinary tract was drained with a nephrostomy or internal ureteral stent. Two patients underwent replacement ureteroplasty with tubularized buccal graft, and three patients underwent augmentation ureteroplasty with buccal graft using the onlay method.Results. All operations in this group were carried out without conversions. The average length of the ureteral defect was 4.9 cm (4.0–6.0 cm). The patients did not have severe complications in the postoperative period according to the ClavienDindo classification. One patient underwent treatment for exacerbation of chronic pancreatitis; one man experienced ureteral stent migration, which required restentation. The follow-up period was 1–15 months; one woman developed unextended ureteral restenosis, which was eliminated by endoureterotomy and ureteral stenting. At the moment, all patients are spared from permanent urinary drains, they do not have upper urinary tract obstruction. Conclusion. All operations in this group were carried out without conversions. The average length of the ureteral defect was 4.9 cm (4.0–6.0 cm). The patients did not have severe complications in the postoperative period according to the Clavien-Dindo classification. One patient underwent treatment for exacerbation of chronic pancreatitis; one man experienced ureteral stent migration, which required restentation. The observation period for the patients was 1–15 months, one woman developed short ureteral restenosis, which was eliminated by endoureterotomy and ureteral stenting. At the moment, all patients do not have permanent urinary drains, violations of the urodynamics of the upper urinary tract were not revealed in them.