bluuebunny/crossref_metadata_2025_split huggingface dataset:
Low-Dose vs. Standard-Dose Intravenous Alteplase in Bridging Therapy Among Patients With Acute Ischemic Stroke: Experience From a Stroke Center in Vietnam
Authors: Mai Duy Ton , Dao Viet Phuong , Nguyen Van Chi , Vu Dang Luu , Nguyen Tien Dung , Vuong Xuan Trung , Bui Quoc Viet , Phan Ha Quan , Pham Quang Tho , Le Hoang Kien , Tran Anh Tuan , Nguyen Quang Anh , Dang Phuc Duc , Nguyen Hoang , Phan Hoang Thi 
Published: April 2021

Background: To date, the role of bridging intravenous thrombolysis before mechanical thrombectomy (MTE) is controversial but still recommended in eligible patients. Different doses of intravenous alteplase have been used for treating patients with acute ischemic stroke from large-vessel occlusion (LVO-AIS) in Asia, largely due to variations in the risks for intracerebral hemorrhage (ICH) and treatment affordability. Uncertainty exists over the potential benefits of treating low-dose alteplase, as opposed to standard-dose alteplase, prior to MTE among patients with LVO-AIS.Aim: The aim of the study was to compare outcomes of low- vs. standard-dose of bridging intravenous alteplase before MTE among LVO-AIS patients.Methods: We performed a retrospective analysis of LVO-AIS patients who were treated with either 0.6 mg/kg or 0.9 mg/kg alteplase prior to MTE at a stroke center in Northern Vietnam. Multivariable logistic regression models, accounting for potential confounding factors including comorbidities and clinical factors (e.g., stroke severity), were used to compare the outcomes between the two groups. Our primary outcome was functional independence at 90 days following stroke (modified Rankin score; mRS ≤ 2). Secondary outcomes included any ICH incidence, early neurological improvement, recanalization rate, and 90-day mortality.Results: We analyzed data of 107 patients receiving bridging therapy, including 73 with low-dose and 34 with standard-dose alteplase before MTE. There were no statistically significant differences between the two groups in functional independence at 90 days (adjusted OR 1.02, 95% CI 0.29–3.52) after accounting for potential confounding factors. Compared to the standard-dose group, patients with low-dose alteplase before MTE had similar rates of successful recanalization, early neurological improvement, 90-day mortality, and ICH complications.Conclusion: In the present study, patients with low-dose alteplase before MTE were found to achieve comparable clinical outcomes compared to those receiving standard-dose alteplase bridging with MTE. The findings suggest potential benefits of low-dose alteplase in bridging therapy for Asian populations, but this needs to be confirmed by further clinical trials.
The Psychological and Academic Effects of Studying From the Home and Host Country During the COVID-19 Pandemic
Authors: Wilczewski Michał , Gorbaniuk Oleg , Giuri Paola 
Published: April 2021

Objective:This study explored the psychological and academic effects of studying online from the home vis-à-vis host country during the coronavirus disease 2019 (COVID-19) pandemic in the experience of international students at the University of Warsaw, Poland.Methods:A total of 357 international students from 62 countries (236 in the host country and 121 in the home country) completed an online questionnaire survey 2 months after transition to online learning. We studied students' levels of loneliness, life and academic satisfaction, acculturative stress, academic adjustment, performance, loyalty, and perceptions of the online learning experience.Results:The country-of-residence variable had no statistically significant effects on most psychological and academic variables. Significant effects were observed only for two academic variables. Specifically, students who returned to the home country found online communication with other students more contributing to their online learning experience and exhibited higher academic adjustment than students who remained in the host country. This suggests the positive influence of (peer and familial) support on online learning experience from the home country. Furthermore, a significant difference in experiencing acculturative stress occurred for students in quarantine/self-isolation in the host country, which expands prior literature on the disruptive effects of social distancing on students' mental health. Finally, this study confirmed the expected increased levels of loneliness among self-isolating students in both countries, hence extending prior results to the home- and host-country contexts. No relationship between self-isolation and students' life or academic satisfaction was found, which is explained by the specific nature of the learning-from-home experience.
Development and Validation of a Transfusion Risk Score for Patients Receiving Maintenance Hemodialysis
Authors: Gilbertson David T. , Yan Heng , Xu Hairong , Sinsakul Marvin , Peng Yi , Wetmore James B. , Liu Jiannong , Li Suying 
Published: April 2021

Abstract

Key Points

Variables most predictive of transfusion were previous transfusion, hemoglobin, ferritin, and length of hospitalization at baseline.Our transfusion prediction risk score performed well. It could be further developed into a clinically useful tool.The score could allow clinicians to identify hemodialysis patients most likely to benefit from an anemia treatment to avoid transfusions.

Background
In patients on dialysis with anemia, avoiding red blood cell transfusions is preferable. We sought to develop and validate a novel transfusion prediction risk score for patients receiving maintenance hemodialysis.

Methods
This retrospective cohort study used United States Renal Data System data to create a model development cohort (patients who were point prevalent and on hemodialysis on November 1, 2012) and a validation cohort (patients who were point prevalent and on hemodialysis on August 1, 2013). We characterized comorbidity, inflammatory conditions, hospitalizations, anemia and anemia management, iron parameters, intravenous iron use, and vitamin D use during a 6-month baseline period to predict subsequent 3-month transfusion risk. We used logistic least absolute shrinkage and selection operator regression. In an exploratory analysis, model results were used to calculate a score to predict 6- and 12-month hospitalization and mortality.

Results
Variables most predictive of transfusion were prior transfusion, hemoglobin, ferritin, and number of hospital days in the baseline period. The resulting c-statistic in the validation cohort was 0.74, indicating relatively good predictive power. The score was associated with a significantly increased risk of subsequent mortality (hazard ratios 1.0, 1.22, 1.26, 1.54, 1.71, grouped from lowest to highest score), but not with hospitalization.

Conclusions
We developed a transfusion prediction risk score with good performance characteristics that was associated with mortality. This score could be further developed into a clinically useful application, allowing clinicians to identify patients on hemodialysis most likely to benefit from a timely, proactive anemia treatment approach, with the goal of avoiding red blood cell transfusions and attendant risks of adverse clinical outcomes.
O duplo movimento da publicidade: rastros, experiências, embates, engajamento e diálogo nas Redes Sociais Digitais.
Authors: Lins Letícia Alves , Araújo Gilvan Ferreira de 
Published: April 2021

O cenário contemporâneo traz mudanças significativas para a publicidade. As redes sociais possibilitam um duplo movimento: de um lado aumenta a possibilidade de diálogo e posicionamento do/as interagentes frente às propostas argumentativas das campanhas publicitárias, relação marcada por embates de sentido. Por outro lado, os rastros deixados pelo/as internautas na rede retroalimentam os anunciantes de informações que, uma vez apreendidas, podem ser usadas a seu favor. Apesar dessa relação ser cunhada pelos avanços tecnológicos, partimos do pressuposto de que qualquer movimento tem por trás uma motivação anterior que é humana. Os meios de comunicação só ganham concretude e se desenvolvem a partir e pela ação humana. É esse movimento que o artigo busca apreender a partir de um caso específico ocorrido na fanpage da Skol em março de 2017.
Atlas Mnemosyne e Saber Visual: atualidade de Aby Warburg diante das imagens, mídias e redes
Authors: De Sousa Maciel Jane Cleide 
Published: April 2021

A compreensão das imagens engendrada por uma observação atenciosa aos detalhes expressivos ao mesmo tempo em que considera sua inscrição dentro das situações socioculturais e de historicidade dos meios é um legado inspirador deixado por Abraham Warburg para a teoria da imagem. Neste artigo, iremos apresentar de maneira concisa as singularidades de sua ciência da cultura, considerando em particular sua paradigmática e derradeira obra, o Atlas de Imagens Mnemosyne, que será debatido como forma de pensamento e de expressão que possui múltiplas linhas de convergência com as imagens, mídias e redes da atualidade. A partir da teoria de Warburg e também de autores (AGAMBEN, 2012; DIDI-HUBERMAN, 2013a, 2013b; GUINZBURG, 1989; SIEREK, 2009) que comentam e atualizam esse arcabouço analítico, veremos como a “Forma Atlas” pode ser entendida como instrumento de orientação, de escrita e de leitura das imagens, pertinente aos estudos sobre a cultura visual contemporânea.
EVALUATING AND PREVENTING POLLUTION FROM NAVIGATION IN THE BLACK SEA COASTAL AREAS IN THE CONTEXT OF CLIMATE CHANGE
Authors: GÎRLEANU Alina , RUSU Eugen 
Published: April 2021

Nowadays, studying climate change of the coastal zones is of utmost importance, due to the fact that global warming endangers in particular sea coast regions. As a matter of fact, the scientist and one of the founders of physical climatology, Budiko, in 1972, stated that first of all, due to the rising use of fossil fuels, a significant rise in the air temperature will occur, then extensive flooding of coastal areas will be caused by this appearance of climate change, ecomigration will follow, along with massive economical loss, generating a chain-reaction process.
Taking the Black Sea into consideration, it is more than clear that pollution has reached record levels during the last decades. Hydrocarbons, which are naturally-occurring compounds that form the basis of coal, natural gas and crude oil, are responsible for more than 80% of energy consumption, but unfortunately, it is now common knowledge that using them as the primary source of energy, it contributes to increasing climate changes.
Furthermore, marine accidents, such as collisions and explosions, contribute significantly to pollution, with consequences on coastal ecosystems and onshore human activities. This paper aims to lay emphasis on the impact that navigation, alongside with climate change has on the marine environment and analyse the available data regarding the marine accidents using satellite monitoring in order to control and prevent disasters that may occur while operating ships at sea.
DESIGN OPTIMIZATION OF A CIVIL STRUCTURE USING NUMERICAL SIMULATIONS
Authors: VLĂDULESCU Florian 
Published: April 2021

This optimization study aims to determine the effect of each input parameter on the output parameters, how the input parameters can interact with each other and also it is emphasized the determination of the values for the input parameters that optimize the responses. In this study, the objective is to obtain an optimal configuration for a resistance structure specific to a telecommunications tower. For this purpose, a variable geometric model using design parameters is created, based on which a 3D finite element model (FEM) is obtained, which is used in the optimization study. The FE model is updated automatically for each version of geometric model and is made using beam and shell elements. Design of Experiments (DOE) methodology allows for using a mathematical model that predicts how input parameters interact to create output responses in an optimization process. Parameters’ correlation and monitoring allow for identifying important parameters and the correlation matrix and sensitivity graphs also help understanding the parametric relationships. Variation limits for design parameters are defined and these parameters can have integer or fractional values.
RESEARCH ON THE COMBUSTION PROCESS OF NAVAL DIESEL ENGINES TO REDUCE POLLUTANT EMISSIONS
Authors: DUMITRACHE Mihail Lucian , BUZBUCHI Nicolae 
Published: April 2021

The modelling of the process in internal combustion engines has been a permanent concern of specialists in the field. The complexity of the phenomena and the strong interdependence between them make the approach particularly difficult. The application of the provisions of the Protocol required the signatory countries, from 2010, to put in place measures to reduce nitrogen oxide emissions, especially in coastal areas, the most affected being, in the first instance, port technical vessels.
AN ANALYSIS OF THE EFFECT OF THE BODY VIBRATIONS ON THE HUMAN PERFORMANCES
Authors: PICU Laurentiu , RUSU Eugen 
Published: April 2021

In this paper, we wanted to check if classical music can improve the intellectual and practical skills of those who work in very difficult conditions. For this, we exposed 44 male students, aged 21-24, with normal BMI (19-24), in perfect health, to four types of stressors, when there is classical music as a sic sound background and when we have no music. The stressors used were vibration, excessive temperature, and humidity as well as very strong light. Two pieces of music were chosen as background: "Eine Kleine Nachtmusik" (Mozart) and "Minuetto" (Boccherini). These 2 musical works were chosen because they are cheerful, optimistic, written in an alert rhythm, easily recognizable even if the audience is not music lovers. Students’ performance was measured using 3 tests: the Purdue Pegboard Test, the Stroop Color and Word Test and also Comparing of Names Test. The results show that neither Mozart's music nor Boccherini's music led to an improvement in student performances; on the contrary, better results were obtained when it was silence.
Pemodelan Penggunaan E-Money Pada E-Parking Kota Makassar
Authors: Ihsan Hisyam , Side Syafruddin , Wulandari Emi 
Published: April 2021

Penelitian ini bertujuan untuk membangun model penggunaan E-Money pada E-Parking tipe SIRI (Susceptible – Infected – Recovered – Infected) di Kota Makassar. Asumsi yang ditambahkan adalah manusia yang telah menggunakan E-Money dapat kembali menggunakan uang tunai pada pembayaran parkir. Model ini dibagi menjadi tiga kelas yaitu rentan/berpotensi menggunakan parkir, pengguna uang tunai, dan pengguna E-Money. Data yang digunakan adalah data primer yang diperoleh dengan survey langsung dilapangan. Survey dilakukan dengan membagikan angket kepada 100 responden secara acak. Model matematika tipe SIRI digunakan untuk menentukan titik equilibrium. Hasil simulasi model tipe SIRI menghasilkan bilangan reproduksi dasar (R0) sebesar 0.021021 yang berarti bahwa penggunaan uang tunai dapat mengalami penurunan yang menyebabkan penggunaan E-Money akan meningkat dalam kurun waktu tertentu.Kata Kunci: Titik Equilibrium, Bilangan Reproduksi Dasar, Uang Elektronik, Parkiran Elektronik, Model SIRI This study aims to build a model of the use of E-Money in E-Parking type SIRI (Susceptible - Infected - Recovered - Infected) in Makassar City. The added assumption is that people who have used E-Money can may return to cash payments on parking. This model is divided into three classes, namely vulnerable / potentially using parking, cash users, and E-Money users. The data used are primary data obtained by direct survey in the field. The survey was conducted by distributing questionnaires to 100 respondents randomly. The SIRI type mathematical model is used to determine the equilibrium point. The simulation results of the SIRI type model produce a base reproduction number (R0) of 0.021021 which means that the use of cash can decrease which causes the use of E-Money will increase in a certain period of time. Keywords: Equilibrium Point, Basic Reproduction Numbers, E-Money, E-Parking, SIRI Model
PARADIGMA KONTEMPORER SISTEM PEMBELAJARAN AL QUR’AN PADA ANAK USIA DINI DI LEMBAGA TAHSIN QUR’AN KAUQOY PRIVATE
Authors: Shofiyah Nur , Masruchan Masruchan 
Published: April 2021

Al-Qur’an sebagai kalamullah mengandung asas pengajaran karena mencakup ajaran-ajaran Islam yang menata kehidupan kaum muslimin dalam segala aspek di dunia dan akhirat. Pemahaman al-Qur’an terutama bagi anak harus dimulai sejak dini melalui kegiatan membaca dan menulis yang dilanjutkan dengan memahami ajaran agama Islam secara bertahap. Namun faktanya, sistem pembelajaran Al Qur’an terutama bagi anak usia dini masih monoton dan kurang menarik karena masih menerapkan paradigma pembelajaran yang berpusat pada pengajar. Penelitian ini bertujuan untuk mendeskripsikan sistem pembelajaran al-Qur’an di lembaga Tahsin Qur’an Ka’Uqoy Private dengan jenis penelitian kualitatif deskriptif dan menggunakan teknik pengumpulan data observasi, wawancara, serta dokumentasi. Hasil penelitian menunjukkan bahwa sistem pembelajaran al-Qur’an di lembaga Tahsin Qur’an Ka’Uqoy menerapkan paradigma konstruksionisme dengan hanya menggunakan satu peraga yaitu alat indera melalui ragam interaksi dengan lingkungan sekitarnya seperti melihat, mendengar, menyentuh, dan merasakannya. Melalui pengaktifan indrawi, seorang anak bisa membangun gambaran dalam dunia belajarnya. Lembaga ini telah mencetak pengajar yang mampu mengajarkan Al-Qur’an dengan mudah untuk difahami terutama bagi anak usia dini dengan cara ikut terlibat langsung dalam mencerna, mengolah, mengalami, memahami, merasakan dan mempraktikkan isi kandungan Al-Qur’an dengan fun learning sehingga para anak usia dini lebih mudah dalam menangkap ilmu Al-Qur’an dan menerimanya dengan senang hati.

Al-Qur'an as kalamullah contains teaching principles because it includes Islamic teachings that organize the lives of Muslims in all aspects. Understanding the Qur'an, especially for children, must start early through reading and writing activities which are continued by gradually understanding the teachings of Islam. However, the fact is that the learning system of the Qur'an, especially for early childhood, is still monotonous and less interesting because it still applies a teacher-centered learning paradigm. This study aims to describe the al-Qur'an learning system in the Tahsin Qur'an ka'Uqoy Private institution with a descriptive qualitative research that uses some data collection techniques. The results showed that the al-Qur'an learning system in the tahsin Qur'an ka'Uqoy institution applies the constructionism paradigm by using only an instrument namely the senses through various interactions with the surrounding environment such as seeing, hearing, touching, and feeling it. Through sensory activation, a child can build a picture in the world of learning. This institution has produced teachers who are able to teach the Qur'an easily to be understood, especially for early childhood by being directly involved in digesting, processing, experiencing, understanding, tasting and practicing the contents of the Al- The Qur'an with fun learning so that early childhood can more easily grasp the knowledge of the Qur'an.
Critical analysis of the object of the crime as an element of the corpus delicti
Authors: Veklenko Sergey , Semchenkov Igor' 
Published: April 2021

The article provides evidence of the groundlessness of recognizing the object of a crime as an element of the corpus delicti.
The substantiation of this conclusion in relation to such types of criminal offenses as preparation for a crime, attempted crime, incitement to a crime, aiding in a crime and the act of the organizer of a criminal offense is carried out by demonstrating that they do not even come into contact with the object of the crime and don’t have a direct impact on it.
The proof that the object of the crime is not an integral part of the criminal act, expressed in causing harm, is carried out in two directions - in relation to crimes that harm the internal benefits of a person, for example, his life or health, and in relation to crimes that harm external benefits of people recognized as objects of criminal law protection, in particular, such as public order, public safety, etc.
It is shown that the object of a crime in the form of a person’s internal goods cannot be a constituent part of a crime because these benefits are inside of their owner, and he himself is an element of some social group formation (social system), but not an element of a crime committed against him.
The argument that external objects of a crime are not an integral part of a crime is based on the results of a detailed analysis of the process of causing harm. The results of such an analysis, carried out using the categories of the part and the whole, demonstrate the fundamental impossibility of isolating any constituent elements (parts) in the process of causing harm. In this process, it is possible to single out only certain of its phases and stages, but not its component parts.
Public order as a social good protected from hooliganism by the criminal law of the Republic of Armenia
Authors: Denisov Sergey , Jumshudyan Hovhannes 
Published: April 2021

The article is devoted to the study of the essence of public order as the object of legal protection against hooliganism. Public order as a complex differentiated category is formed from numerous volitional relationships between people in society being manifested in their behavior and actions as a result of their conscious activity. The state adopting certain laws exerts considerable influence on interpersonal relations monitoring their compliance and execution. Public order as the object of criminal legal protection from hooliganism is a complex socio-legal category based on the relations between members of society and their obedience to moral standards indicating the relevance of the topic of the article.
The article examines the definition of the concept of «public order» expressed by the Court of Cassation of the Republic of Armenia, as well as views put forward in the legal literature of the Republic of Armenia and the Russian Federation. The concept of «public order» is considered in both broad and narrow meanings.
In addition, the problems of possible social regulators that determine the criteria for acceptable behavior of an individual within the framework of public order are discussed. In the field of constitutional and legal regulation, the currentle gislation of the Republic of Armenia on public order, in particular the legal acts defining the criteria for permissible behavior of an individual within the framework of public order, has been investigated.
As a result of the study, proposals to bring the concept of «public order» used in Article 258 of the Criminal Code of the Republic of Armenia into line with the principle of legal certainty were made.