bluuebunny/crossref_metadata_2025_split huggingface dataset:
(Re)discussing the drug administration technique by the intramuscular route: a systematic review / (Re)discutindo a técnica de administração de medicamentos pela via intramuscular: revisão sistemática
Authors: Gomes Barbara Ragasse Pereira , Paes Graciele Oroski , Traverso Fabíola Alves 
Published: May 2021

Objetivos:Identificar a produção do conhecimento da enfermagem atrelado a técnica de administração de medicamentos pela via intramuscular; descrever as divergências, congruências, e ocorrência de complicações acerca da técnica; e analisar as recomendações descritas na literatura com as melhores práticas e atualizações clínicas na enfermagem. Método: Revisão sistemática sem meta-análise.Realizada busca nas bases de dados LILACS, Pubmed, Medline, DEDALUS, Portal de Evidência em Saúde e Bibliotecas SciELO e Cochrane, no período de 1993 a 2012,totalizando 16 estudos. Resultados:Os estudos evidenciaram divergências na variações de demarcação da região ventroglútea; realização de antissepsia; e aplicação de pressão antes da administração intramuscular.Consonâncias na aspiração do conteúdo da seringa após inserção da agulha na massa muscular, rodízio do local de aplicação durante sequências de injeções IM, dentre outros.Conclusão:A incorporação das melhores evidências permite a execução segura da técnica intramuscular, gerando conforto ao paciente e excelência na assistência.
The bicycle accident in Brazil: an integrative review / Os acidentes de bicicleta no Brasil: uma revisão integrativa
Authors: Tavares Fábio Lucio , Costa Leite Franciele Marabotti , Lima Eliane de Fatima Almeida , Mendes de Melo Evandro Bernardino , Monteiro da Silva Thiago Augusto Soares , Coelho Maria José 
Published: May 2021

Objetivo: analisar a produção científica acerca dos acidentes de bicicleta produzidos no Brasil. Método: revisão integrativa com propósito de responder à questão “Qual o conhecimento científico já produzido no Brasil sobre acidentes de bicicleta?” Os dados foram coletados no período de junho a agosto de 2015 nas bases MEDLINE e LILACS, artigos em português e inglês, utilizando-se os descritores: “ciclismo”, “acidentes de trânsito”, “Brasil”, “saúde pública”, “epidemiologia” e “mortalidade”. Resultados: Foram analisados 15 artigos agrupados em duas categorias: perfil epidemiológico das lesões e perfil epidemiológico dos acidentes. Conclusões: Nota-se ser necessário ampliar os estudos referentes a este tema, nos diferentes estados brasileiros, uma vez que os acidentes de bicicleta passam a ter papel importante no campo da Saúde, em especial para a Enfermagem, que irá planejar e implementar cuidados com as vítimas.
Educational technology on oral contraception: construction shared with nurses reproductive assistance / Tecnologia educacional sobre contracepção oral: construção compartilhada com enfermeiros da assistência reprodutiva
Authors: Souza Teixeira Lorena Francielly , Rodrigues Ivaneide Leal Ataide , Nogueira Laura Maria Vidal 
Published: May 2021

Objetivo: descrever conhecimentos e práticas de enfermeiros no contexto da contracepção oral e construir, de forma compartilhada, uma tecnologia educacional. Metodologia: a pesquisa foi desenvolvida em 09 Unidades da Estratégia Saúde da Família, pertencentes ao município de Ananindeua, localizado na Região Metropolitana de Belém – Pará, tendo como participantes 21 enfermeiros. A coleta de dados ocorreu no período de agosto a novembro de 2015 por meio de entrevista individual com roteiro semi-estruturado e para análise utilizou-se a técnica de análise de conteúdo. Resultados: Contatou-se que os enfermeiros têm amplo conhecimento com relação à contracepção oral. E suas práticas, embora pertinentes ao que está preconizado para essa clientela, encontram-se dificultadas pelas condições de trabalho em suas Unidades. Conclusão: os enfermeiros contribuíram no conteúdo e forma da tecnologia educacional pois consideraram pertinente a sua utilização como importante ferramenta para a educação em saúde.
Knowledge of nurses about the clinical management of breastfeeding: knowledge and practices / O conhecimento do enfermeiro acerca do manejo clínico da amamentação: saberes e práticas
Authors: Souza Rosangela de Mattos Pereira de , Alves Valdecyr Herdy , Rodrigues Diego Pereira , Branco Maria Bertilla Lutterbach Riker , Lopes Fernanda de Oliveira , Santos Márcia Vieira dos 
Published: May 2021

Objetivo: analisar o conhecimento dos enfermeiros na realização das estratégias para o manejo clínico da amamentação. Método: estudo descritivo, exploratório, qualitativo, sendo participantes quarenta e sete enfermeiros das maternidades públicas da Região Metropolitana II do Estado do Rio de Janeiro, entrevistados com base em um roteiro de entrevista semiestruturada, sendo os dados coletados submetidos à análise de conteúdo na modalidade temática. Na análise, optou-se pela formulação de categorias temáticas. Resultados: no manejo clínico do aleitamento materno evidencia-se o conhecimento teórico e científico acerca da amamentação pelos enfermeiros, além de serem eles facilitadores da prática da amamentação, intervindo nos agravos resultantes da prática do aleitamento materno inadequado. Conclusão: Percebeu-se que os enfermeiros estão capacitados com competência e habilidades necessárias para favorecer a saúde da mulher e da criança em prol do sucesso da amamentação.
Nursing care in Sickle Cell Disease in the Family Health Strategy / Assistência de enfermagem na Doença Falciforme na Estratégia Saúde da Família
Authors: Almeida Mayron Morais , Santos Márcia Sousa , Silva Francisco Wharleson Torres da 
Published: May 2021

Objetivo: Avaliar os cuidados realizados por enfermeiros as pessoas vivendo com Anemia Falciforme. Métodos: Estudo exploratório e descritivo realizado com 28 enfermeiros na cidade de Caxias (MA). A análise dos dados ocorreu por meio do software Iramuteq. O estudo foi aprovado pelo Instituto Superior de Educação e Saúde Sinop Eireli com CAAE: 47406315.9.0000.5685. Resultados e Discussão: Houve predominância do sexo feminino e idade variando entre 31 à 40 anos. A maioria dos enfermeiros do estudo demostraram ter conhecimento acerca da temática anemia falciforme, porém afirmaram que não prestam a assistência as pessoas portadores da doença, seja pela falta de pacientes na área de abrangência da UBS, seja pela falta de preparo dos profissionais em prestar uma assistência de qualidade as mesmos. Conclusão: O estudo mostrou que os enfermeiros não prestam uma assistência adequada às pessoas portadores de anemia falciforme. Descritores: Anemia Falciforme, Cuidados de Enfermagem, Estratégia Saúde da Família, Centros de Saúde.
Tailoring PTV expansion to improve the dosimetry of post modified radical mastectomy intensity‐modulated radiotherapy for left‐sided breast cancer patients by using 4D CT combined with cone beam CT
Authors: Zhang Jiyong , Huang Lei , Wu Fangcai , Wang Guoxi , Wu Lili , Huang Baotian , Lin Yan , Li Dongsheng , Ma Changchun 
Published: May 2021

AbstractPurposeOur study aimed to improve the dosimetry of post modified radical mastectomy intensity‐modulated radiotherapy (PMRM‐IMRT) for left‐sided breast cancer patients by tailoring and minimizing PTV expansion three‐dimensionally utilizing 4D CT combined with on‐board cone beam CT (CBCT).MethodsWe enrolled a total of 10 consecutive left‐sided breast cancer patients to undergo PMRM‐IMRT. We measured the intra‐fractional CTV displacement attributed to respiratory movement by defining 9 points on the left chest wall and quantifying their displacement by using the 4D CT, and measured the inter‐fractional CTV displacement resulting from the integrated effect of respiratory movement, thoracic deformation and set up errors by using CBCT. We created 3 different PMRM‐IMRT plans for each of the patients using PTVt (tailored PTV expansion three‐dimensionally), PTV0.5 and PTV0.7 (isotropic 0.5‐ cm and isotropic 0.7‐ cm expanding margin of CTV), respectively. We performed paired samples t test to establish a hierarchy in terms of plan quality and dosimetric benefits. P < 0.05 was considered statistically significant.ResultsThe inter‐fractional CTV displacement (2.6 ± 2.2 mm vertically, 2.8 ± 2.3 mm longitudinally, and 1.7 ± 1.2 mm laterally) measured by CBCT was much larger than the intra‐fractional one (0.5 ± 0.5 mm vertically, 0.5 ± 1.0 mm longitudinally, and 0.3 ± 0.3 mm laterally, respectively) measured by 4D CT. Intensity‐modulated radiotherapy with tailored PTV expansion based on inter‐fractional CTV displacement had dosimetrical advantages over those with PTV0.5 or those with PTV0.7 owing to its perfect PTV dose coverage and better OARs sparing(especially of heart and left lung).ConclusionThe CTV displacement in PMRM‐IMRT predominantly arises from inter‐fraction rather than from intra‐fraction during natural respiration and differs in 3 coordinate axes either inter‐fractionally or intra‐fractionally. Tailoring and minimizing PTV expansion three‐dimensionally significantly improves the dosimetry of PMRM‐IMRT for left‐sided breast cancer patients.
Ultrafast Terahertz Nanoseismology of GaInN/GaN Multiple Quantum Wells
Authors: Mannan Abdul , Bagsican Filchito Renee G. , Yamahara Kota , Kawayama Iwao , Murakami Hironaru , Bremers Heiko , Rossow Uwe , Hangleiter Andreas , Turchinovich Dmitry , Tonouchi Masayoshi 
Published: May 2021

AbstractTerahertz (THz) emission spectroscopy and microscopy are applied to investigate the electron and lattice dynamics of Ga0.8In0.2N/GaN multiple quantum wells (MQWs). The THz emission consists of three distinct, differently timed signals, whose physical mechanisms are attributed to i) laser‐induced ultrafast dynamical screening of built‐in bias electric field in MQWs followed by ii) capacitive charge oscillation of the excited carriers and iii) the coherent acoustic phonon (CAP)‐driven polarization surge at the discontinuity between the GaN capping layer and air. These multifunctional optical responses show strong dependence on the quantum well width and photon energies. The temporal separation between the first and third THz pulses corresponds to the propagation of the CAP across the GaN capping layer of the MQW structure, whose thickness can thus be determined with 10 nm precision.
In‐Situ and Reversible Enhancement of Photoluminescence from CsPbBr3 Nanoplatelets by Electrical Bias
Authors: Wang Ziming , Huang Zhigao , Liu Gaoyu , Cai Bo , Zhang Shengli , Wang Yue 
Published: May 2021

AbstractIn‐situ and real‐time modulation of the optical properties of semiconductor nanoemitters by a CMOS‐compatible strategy holds great promise for developing functional and integrated optoelectronic devices. Herein, the reversible and giant (>13 times) enhancement of the photoluminescence (PL) from inorganic halide perovskite nanoplatelets by electrical bias is demonstrated for the first time. Based on the comprehensive spectroscopic analysis, the improved PL performance is attributed to the dynamic surface healing effect by bias‐induced ion redistribution. The switching from PL quenching to PL enhancement from CsPbBr3 nanoplatelet is manifested at threshold temperature of ≈190 K. Moreover, the temperature dependent measurements unravel the activation energy of 142.8 ± 31.1 meV, corroborating that the drifted species of anion (Br−) or VBr dominates the trap healing process. Accordingly, a three‐stage defect passivation model of the vertical configuration is established. The synergistic effects of ion redistribution and charge injection caused by thermal equilibrium energy band bending on the optical properties of the perovskite is further investigated by contacting the perovskite with indium tin oxide electrode. These results provide novel insight into the photophysical properties of halide perovskites and are beneficial for display and lighting applications in future, especially on‐chip integrated photonics circuits and systems.
Identification of Key Contributive Compounds in a Herbal Medicine: A Novel Mathematic—Biological Evaluation Approach
Authors: Zhang Cheng , Wang Ning , Xu Yu , Tan Hor‐Yue , Feng Yibin 
Published: May 2021

AbstractA pattern or syndrome in response to a multicomponent system is the actual target of herbal medicine treatment. However, it is a substantial challenge to fill the gap between a contributive compound profile in herbal medicine (especially a formula) and its biological features. This study aims to establish a feasible component‐mining strategy, which provides a strong prediction of key compounds in support of experimental and clinical observations. Given interdisciplinary scope of life science and mathematical statistics, the relationship between chemical profile and bioactivities is measured by a model termed mathematical prediction bioactivity, in which gray relational analysis, multiple linear/non‐linear regression analysis (including t‐distributed stochastic neighbor embedding), and radial basis function analysis are involved. R language programming‐dependent analysis is adopted with add‐on packages, including UniDOE, Factoextra, FactoMineR, Factanal, Rtsne, and Nnet. By using this assessment method in a biological experiment, it is identified that 6‐shogaol extracted from Ginger‐Coptis formula (a herbal formula) is beneficial for diabetic retinopathy (DR) treatment. The study provides both a novel compound 6‐shogalol for DR treatment and a new strategy for mining key contributors in a multicomponent system.
Long‐Term Imaging of Wound Angiogenesis with Large Scale Optoacoustic Microscopy
Authors: Rebling Johannes , Ben‐Yehuda Greenwald Maya , Wietecha Mateusz , Werner Sabine , Razansky Daniel 
Published: May 2021

AbstractWound healing is a well‐coordinated process, necessitating efficient formation of new blood vessels. Vascularization defects are therefore a major risk factor for chronic, non‐healing wounds. The dynamics of mammalian tissue revascularization, vessel maturation, and remodeling remain poorly understood due to lack of suitable in vivo imaging tools. A label‐free large‐scale optoacoustic microscopy (LSOM) approach is developed for rapid, non‐invasive, volumetric imaging of tissue regeneration over large areas spanning up to 50 mm with a depth penetration of 1.5 mm. Vascular networks in dorsal mouse skin and full‐thickness excisional wounds are imaged with capillary resolution during the course of healing, revealing previously undocumented views of the angiogenesis process in an unperturbed wound environment. Development of an automatic analysis framework enables the identification of key features of wound angiogenesis, including vessel length, diameter, tortuosity, and angular alignment. The approach offers a versatile tool for preclinical research in tissue engineering and regenerative medicine, empowering label‐free, longitudinal, high‐throughput, and quantitative studies of the microcirculation in processes associated with normal and impaired vascular remodeling, and analysis of vascular responses to pharmacological interventions in vivo.
Tribo‐Induced Color Tuner toward Smart Lighting and Self‐Powered Wireless Sensing
Authors: Wang Jiaqi , Wang Haoyu , Yin Kedong , Zi Yunlong 
Published: May 2021

AbstractThe color‐tuning capability of solid‐state lighting (SSL) systems are highly demanded for smart lighting according to the environmental conditions, as well as wireless sensing of the environmental information. In the meanwhile, state‐of‐the‐art triboelectric nanogenerator (TENG)‐based sensing systems rely on bulky and expensive devices, which require cable connections and additional power consumptions. This work aims at solving these challenges, through developing a tribo‐induced color tuner that can be integrated into the vastly distributed commercial SSL system. This tribo‐induced color tuner includes a concentric color conversion plate consisting of (Sr,Ca)AlSiN3:Eu phosphor and TiO2, a tribo‐induced liquid lens, and a rotary freestanding sliding TENG. The color oscillation between purple and pink is achieved upon the tribo‐charging by the TENG, which reveals the input mechanical motion signals. The signal can be conveniently sent by everywhere‐existed lamps and processed by everyone‐owned smartphone cameras or closed‐circuit televisions. Through this approach, the function of wireless sensing is achieved without the need of preamplification, with no additional power supply required, as demonstrated for wireless sensing of the rotation speed. The smart lighting for underwater photographing is also demonstrated by the color‐tunable SSL system with the best imaging quality achieved.
Explaining output price heterogeneity in Dutch horticulture
Authors: Los Evert , Gardebroek Cornelis , Huirne Ruud 
Published: May 2021

AbstractRecent empirical literature pays increasing attention to farmer‐retail power relations in agricultural supply chains, yet seems to neglect potential differences between prices that primary producers receive for their products. Via both a Markov chain analysis and a hybrid panel data model, we empirically test whether primary producers receive prices in a consistent way and what explains any price differences. Using a unique data set containing individual farm‐specific output prices in various horticultural markets, we show substantial price dispersion across farms and reveal relations between farm characteristics and observed output prices. The Markov analysis shows that the same farms are constantly found in the higher and lower quartiles of the price distribution, implying prices are not distributed randomly. The results of the hybrid panel data model show that characteristics as farm size and production orientation are strongly associated with differences in the obtained output prices as well as the price/cost ratio between farms. [EconLit Citations: D22, D40, L11, Q13].
Patterns of population genomic diversity in the invasive Japanese knotweed species complex
Authors: VanWallendael Acer , Alvarez Mariano , Franks Steven J. 
Published: May 2021

PREMISE
Invasive species are expected to undergo a reduction in genetic diversity due to founder effects, which should limit their ability to adapt to new habitats. Still, many invasive species achieve widespread distributions and dense populations. This paradox of invasions could potentially be overcome through multiple introductions or hybridization, both of which increase genetic diversity. We conducted a population genomics study of Japanese knotweed (Reynoutria japonica), which is a polyploid, clonally reproducing invasive species that has been notoriously successful worldwide despite supposedly low genetic diversity.
METHODS
We used genotyping by sequencing to collect 12,912 SNP markers from 88 samples collected at 38 locations across North America for the species complex. We used alignment‐free k‐mer hashing analysis in addition to traditional population genetic analyses to account for the challenges of genotyping polyploids.
RESULTS
Genotypes conformed to three genetic clusters, likely representing Japanese knotweed, giant knotweed, and hybrid bohemian knotweed. We found that, contrary to previous findings, the Japanese knotweed cluster had substantial genetic diversity, though it had no apparent genetic structure across the landscape. In contrast, giant knotweed and hybrids showed distinct population groups. We did not find evidence of isolation by distance in the species complex, likely reflecting the stochastic introduction history of this species complex.
CONCLUSIONS
The results indicate that clonal invasive species can show substantial genetic diversity and can be successful at colonizing a variety of habitats without showing evidence of local adaptation or genetic structure.
Natural history of alpha‐thalassemia X‐linked intellectual disability syndrome: A case report of a 45‐year‐old man
Authors: Arvio Maria , Lähdetie Jaana 
Published: May 2021

AbstractWe have followed the clinical course of a 45‐year‐old man with a severe form of alpha‐thalassemia X‐linked intellectual disability syndrome for 40 years. The most challenging health issue is the combination of rumination, drooling, and vomiting. The patient achieved present adaptive and motor skills in his teenage years. He is able to move on the floor in a sitting position. He seems happy and has not shown any behavioral or psychiatric symptoms. New signs not described in the literature before are accelerated growth after puberty and atypical sleeping position with upper body resting on legs.
Incidence and characteristics of medical emergencies related to dental treatment: a retrospective single‐center study
Authors: Obata Kyoichi , Naito Hiromichi , Yakushiji Hiromasa , Obara Takafumi , Ono Kisho , Nojima Tsuyoshi , Tsukahara Kohei , Yamada Taihei , Sasaki Akira , Nakao Atsunori 
Published: May 2021

AimAlthough uncommon, medical emergencies arise in general dental practice. Inadequate data on their severity and frequency makes targeting medical education for general dental practitioners difficult. This also makes planning for unexpected events challenging for practitioners and makes collaborating with emergency physicians burdensome. We aimed to clarify the incidence and characteristics of a dental outpatient department’s medical emergencies.MethodsThis single‐center, retrospective, observational study was undertaken with patients who visited the dental outpatient department of Okayama University Hospital during the 8‐year period. The primary outcome of the study was to identify the incidence and characteristics of medical emergencies in the dental outpatient department. Then we examined the timing of medical emergencies, administered medications, and final disposition (home/admission).ResultsDuring the period, 1,146,929 patients were enrolled. Forty‐two patients (0.0037%) were consulted as medical emergencies. More than 60% of the incidents were vasovagal syncope, and dehydration and hypoglycemia were the second most prevalent at 9.5%. The most common types of dental treatments were tooth extraction (45.2%), followed by general dental treatment (28.6%), and other dental surgery such as implant placement (14.3%). Types of medical emergencies occurred equally before, during, and after dental treatment. Antihypertensive agents, sedatives, or glucose were used. For patients with emergencies, 90.5% recovered during the day and returned home, and 9.5% were hospitalized.ConclusionThe incidence of medical emergencies was low in our dental outpatient department. Knowledge of basic management principles, regular education for emergency care, and practicing first aid skills are mandatory for safe patient management.
π‐Stacked Donor–Acceptor Dendrimers for Highly Efficient White Electroluminescence
Authors: Wang Xingdong , Hu Jun , Lv Jianhong , Yang Qingqing , Tian Hongkun , Shao Shiyang , Wang Lixiang , Jing Xiabin , Wang Fosong 
Published: May 2021

Abstractπ‐Stacked dendrimers consisting of cofacially aligned donors and acceptors are developed by introducing three dendritic teracridan donors with orthogonal configuration and three triazine acceptors in periphery of hexaphenylbenzene skeleton. The dendritic structure and orthogonal configuration of teracridan not only make their outer acridan segments approaching to acceptor in close distance, but also fix donor and acceptor in face‐to‐face alignment, leading to through‐space charge transfer emission with thermally activated delayed fluorescence (TADF) effect. By regulating charge transfer strength via substituent effect of acceptor, emission color of the dendrimers can be tuned from blue to yellow/red region. Solution‐processed two‐color white organic light‐emitting diodes (OLEDs) based on blue and yellow π‐stacked donor–acceptor dendrimers exhibit the maximum external quantum efficiency of 20.6 % and maximum power efficiency of 58.9 lm W−1, representing the state‐of‐the‐art efficiency for all‐TADF white OLEDs by solution process.