bluuebunny/crossref_metadata_2025_split huggingface dataset:
PSIV-B-18 Performance response of weanling and grower pigs fed graded levels of poultry byproduct meal (PBM) in the diet
Authors: Lee Jung Wook , Chevalier Tyler B , Monegue Jim J , Lindemann Merlin D 
Published: October 2021

Abstract
Two experiments were conducted to investigate effects of feeding graded levels of PBM on performance of weanling pigs and to evaluate feed preference for PBM-based diets relative to spray-dried plasma protein (SDPP)-based diets. A third experiment evaluated PBM in grower diets on performance. In Exp. 1, 120 pigs [body weight (BW) 7.1 ± 0.6 kg] were randomly allotted to 1 of 5 treatments (0, 1, 2, 3, or 5% PBM) and housed 4 pigs/pen for a 28-d growth trial. In Exp. 2, 60 pigs (BW 6.7 ± 1.4 kg) were randomly allotted to 1 of 3 comparisons including: Comparison 1) 0% PBM vs. 2% PBM, Comparison 2) 0% PBM vs. 2% SDPP, and Comparison 3) 2% PBM vs. 2% SDPP and housed 4 pigs/pen for a 28-d preference trial; pigs were provided ad libitum access to feeders; feeder location was switched 3 times/wk. In Exp. 3, 120 pigs (BW 25.9 ± 2.1 kg) were randomly allotted to 1 of 4 treatments (0, 1.25, 2.5 or 5% PBM) and housed 5 pigs/pen for a 41-d growth trial. Increasing PBM from 0 to 5% in Exp. 1 resulted in no differences in ADG (398, 417, 424, 432, and 428 g) or G:F (0.675, 0.686, 0.733, 0.711, and 0.717). Feed preference results (Exp. 2) demonstrated that pigs consumed a higher percentage (76 vs. 24%, P &lt; 0.01) of their total feed intake from the 2% PBM-based diet compared to the 2% SDPP-based diet (Comparison 3). In Exp. 3, increasing PBM for grower pigs resulted in no differences in ADG (1007, 1025, 1002, and 1025 g) or G:F (0.484, 0.472, 0.484, and 0.478). Thus, feeding PBM up to 5% of the diet had no effect on overall performance of nursery or grower pigs, indicating it is an acceptable option as a feed ingredient.
PSIV-B-27 Effect of feed flavour on the feeding behaviour and kinetics of daily feed intake of lactating high-prolific sows during summer
Authors: Silva Bruno Alexander N , Eskinazi Simon , Jacob David V , Araújo Wagner , Ataíde Iara , Evangelista Rafaela , Motta Stephane A , Rebordoes Flavio Igor G , Araújo Dalton , Cardoso Larissa A , Habit Steve , Gonçalves Mateus F , Cardoso Hysla M , Brito Sara , Martins Larissa 
Published: October 2021

Abstract
Increasing voluntary feed intake of the sow is a major challenge for nutritionists in tropical climate conditions. The present study aimed to evaluate the impact of the dietary supplementation of a feed flavour for sows during lactation on their feeding behavior and kinetics of daily feed intake under tropical conditions. A total of 60 high-prolific mixed parity sows divided into 10 batches of 6 sows each were used, distributed in a completely randomized experimental design among 2 dietary treatments (0 or 500 g/ton of Krave®, Adisseo). The average meal size was 107 g/meal lower in sows fed the control diet when compared with flavour fed sows. Daily feed intake was greater in the flavored diet than in the control (6,417 vs. 5,362 g/d; P &lt; 0.05). The flavor improved ingestion time (58.4 vs. 46.6 min/ d, respectively flavour and control; P &lt; 0.05). Sows receiving flavor showed a higher nocturnal (704 vs. 583 g/meal) and diurnal (678 vs. 582 g/meal) feed intake. Sows also showed a higher voluntary intake between 00:00 and 10:00 am, which was equivalent to 83% of the total daily feed intake. From a comparison of hourly feed intakes or variations from hour to hour (during 24 h), the nycthemeral pattern of feed intake peaked twice daily for both dietary treatments. However, the size of the peak was greater (P &lt; 0.05) for flavour fed sows when compared with the control at 0400 and 1900 h (Figure 1a). Diets also influenced on kinetics of daily feed intake during the lactation period.Feed intake was higher for the flavour fed sows from d 3 to 8 and from d 10 to 24 (Figure 1b; P &lt; 0.05).In conclusion, the strategic use of a feed flavour to manipulate the sensorial properties of feed is a viable strategy to increase the sows’ voluntary feed intake.
PSIV-B-24 Dietary supplementation of botanicals changed blood profiles and intestinal morphology of weaned pigs experimentally infected with a pathogenic Escherichia coli
Authors: Wong Braden , He Yijie , Kim Kwangwook , Xu Sharon , Lingga Christopher , Wall Emma , Liu Yanhong 
Published: October 2021

Abstract
The objective of this study was to investigate the effects of dietary botanical supplementation on blood profiles and intestinal morphology of weaned piglets experimentally infected with a pathogenic F18 Escherichia coli (E. coli). Sixty weaned piglets (around 21 days old; 7.15 ± 0.97 kg) were individually housed and randomly allotted to one of five dietary treatments (n = 12): negative control (NC), positive control (PC), high dose of botanicals blend 1 (BB1, 100 mg/kg), and low or high dose of botanicals blend 2 (BB2, 50 mg/kg and 100 mg/kg). The experiment lasted 28 days: from day -7 to +21 relative to E. coli inoculation. All piglets except the NC group were orally inoculated with F18 E. coli (10 cfu per dose, 3 doses) for 3 consecutive days. Blood samples were collected on d 0, 5, 14, and 21 post-inoculation (PI) to perform complete blood count test. Intestinal segments were collected on d 5 and 21 PI for intestinal morphology analysis. Data were analyzed by ANOVA using PROC MIXED of SAS with a randomized complete block design. E. coli infection reduced (P &lt; 0.05) neutrophils and lymphocytes, but increased (P &lt; 0.05) monocytes on d 4 PI. Pigs supplemented with 100 mg/kg BB2 had less (P &lt; 0.05) lymphocytes than pigs in PC on d 4 PI. Pigs fed with 50 mg/kg BB2 had lower (P &lt; 0.05) lymphocytes and monocytes then pigs in PC on d 21 PI. Pigs supplemented with 100 mg/kg BB2 had the greatest (P &lt; 0.05) duodenal villi width, jejunum villi height and area, and colon crypt depth then pigs in PC on d 5 PI. In conclusion, dietary supplementation of botanicals tended to affect systemic immunity and enhance intestinal morphology of weaned pigs infected with E. coli.
PSVI-2 Effects of natural capsicum extract as a substitute for chlortetracycline on growth performance, nutrient utilization, antioxidant status, immune function, and meat quality in broilers
Authors: Liu Sujie , Wang Jian , He Tengfei , Liu Hansuo , Piao Xiangshu 
Published: October 2021

Abstract
A total of 168 one-day old broilers (average BW 46.4 ± 0.6 g) were selected to determine effects of natural capsaicin extract (NCE) as a substitute for chlortetracycline (CTC) on performance, antioxidant capacity, immune function and meat quality of broilers [Founded by NSFC (31772612)]. Broilers were randomly allotted into 3 dietary treatments (n = 7) including a corn-soybean meal basal diet (CON), a basal diet + 75 mg/kg CTC (CTC), and a basal diet + 80 mg/kg NCE (NCE). The experiment contained phase 1 (day 1 to 21) and 2 (day 22 to 42). Compared with CON, broilers from NCE showed higher average daily gain at all stages (P &lt; 0.05). On day 42, organic matter, crude protein and gross energy digestibilities of broilers from NCE were higher than those from the other two groups (P &lt; 0.05). Higher percentage of bursa of Fabricius was observed in broilers fed NCE diets compared with CON (P &lt; 0.05). Trypsin and lipase activities in the pancreas of broilers from NCE were higher than those from CON (P &lt; 0.05). Breast muscle of broilers fed NCE diets showed lower L* values compared with CON (P &lt; 0.05). Broilers from NCE also showed higher levels of serum total antioxidant capacity, glutathione peroxidase, superoxide dismutase, lower levels of interleukin-1β and tumor necrosis factor-α compared with broilers offered CON diets (P &lt; 0.05). Compared with CON, lower concentrations of serum urea-N, low-density lipoprotein cholesterol and total cholesterol, higher growth hormone level were observed in broilers fed NCE diets (P &lt; 0.05). In conclusion, supplementing 80 mg/kg of NCE to diets could improve growth performance, nutrient digestibility, antioxidant and immune function, and meat quality of broilers. Moreover, broilers fed NCE diets exhibited similar growth performance and health status to those offered chlortetracycline (CTC) diets.
PSVI-9 Effects of dietary boron supplementation on growth performance, fasting and postprandial serum insulin, and glucose concentration of pigs
Authors: Chevalier Tyler B , Lindemann Merlin D 
Published: October 2021

Abstract
A 49-d experiment evaluated the effects of supplemental boron (B) on growth, and serum insulin and glucose concentration of pigs. Crossbred pigs [n = 48; initial body weight (BW) 19.18 ± 0.29 kg] were randomly allotted to 1 of 4 diets based on BW and sex. Diets were corn-SBM-based, formulated to meet NRC (2012) nutrient requirement estimates, and were supplemented with 0, 25, 50, or 100 mg B/kg diet as sodium tetraborate decahydrate. On d 20 and 41, blood samples were collected. Fasting samples were collected following an overnight fast; then a postprandial sample was taken approximately 50 minutes after the pigs had 10 minutes of ad libitum access to feed. Samples were processed and serum analyzed for insulin and glucose concentration. Increasing B levels resulted in a linear decrease for overall ADG (0.87, 0.86, 0.85, and 0.82 kg, P = 0.02). On d 20, supplemental B resulted in a quadratic response on fasting serum glucose concentration (5.25, 4.80, 4.65, and 5.01, P = 0.03) and a linear decrease in postprandial serum insulin concentration (29.1, 25.5, 18.2, and 18.1 µU/mL, P = 0.02). Furthermore, there was a tendency for a linear decrease in fasting insulin:glucose ratio (0.85, 0.84, 0.42, and 0.59, P = 0.08), which became more noticeable during the postprandial state (3.96, 3.63, 2.63, and 2.73, P = 0.02). Again on d 41, there was a quadratic response on fasting serum glucose concentration (4.32, 4.07, 3.91, and 4.68, P = 0.01) with supplemental B. Results suggest that supplemental boron may impact serum insulin and glucose concentrations by reducing the amount of insulin needed to maintain glucose concentrations. However, higher levels of supplemental boron did result in suppressed growth performance. Thus, additional research is warranted to determine the optimum level of supplemental B.
PSVI-8 Effects of a mycotoxin deactivator on performance of gestating and lactating gilts fed diets containing added mycotoxins
Authors: Siqueira Sinthia , De Brito Hébert , Araújo Wagner , Neves Hélio , Benfato Mara , Canta Diego , Preveraud Damien , Gloria Eduardo , Jacob David V , Silva Bruno Alexander N , Ataíde Iara , Rebordoes Flavio Igor G , Gonçalves Mateus F 
Published: October 2021

Abstract
The present study aimed to evaluate the impact of a mycotoxin deactivator in diets containing added mycotoxins for gestating and lactating gilts on their performance. A total of 60 gilts (LD x LW) were used. After insemination the gilts were distributed among 3 dietary treatments according to a randomized block design: a negative control (CON); mycotoxin positive control (Myc); and a positive control added a mycotoxin deactivator (Myc+Deact 2 kg/ton; Unike®Plus, Adisseo). The total mycotoxins levels added to the diets 2 and 3 from d 75 of gestation until farrowing were: DON at 2.5 mg/kg, FBs at 10 mg/kg, and ZEA at 0.75mg/kg. Sows received the experimental diets from d 75 of gestation until weaning (i.e. 21 d). At farrowing, total number of piglets born, born alive, stillborn, and mummies were measured. Piglets were individually weighed 24-h post-farrowing, and at weaning to determine litter performance during lactation. The effects of diet composition, blocks and initial weight were tested according to a general linear procedure analysis of variance (GLM procedure of SAS). During gestation, treatments influenced (P = 0.022) sow mortality rate: CON had no mortality and Myc 15.8% and Myc+deact 10.5%. Same observation was made for the lactation period (P = 0.017): CON showed a lower mortality rate compared to the mycotoxin fed sows (5.0 vs. 31.2 vs. 11.8%, respectively for CON, Myc and Myc+deact). Sow milk production yield was greater (P = 0.021) in CON (11.66 vs. 9.53 vs. 9.67 kg/ d, respectively for CON, Myc and Myc+deact). As a consequence of that, treatments also influenced piglet (P = 0.047) and litter (P = 0.048) weight with a higher value for CON sows, followed by Myc+deact and Myc. Our findings showed that the use of the deactivator can mitigate the negative effects on performance when animals are subjected to diets contaminated by challenging levels of mycotoxins.
National elections, sub-national growth: the politics of Turkey’s provincial economic dynamics under AKP rule
Authors: Luca Davide 
Published: October 2021

AbstractDespite a large body of work on the impacts of institutions on subnational growth and development, economic geographers have, in the last decades, frequently overlooked the role of politics and, in particular, that of national political economies. Drawing on the political science literature, the article argues that studying national political dynamics is still key to understand the cumulative process of uneven regional development. Using data from Turkey over the period 2004–2016, the article shows how national electoral politics and government actions have significantly affected provincial growth patterns. The impact is substantive and increases in election years. Results also suggest that the central government may have influenced sub-national growth trajectories in different ways, including boosting the construction sector and expanding public employment.
The Phenomenology of Healing: Eight Ways of Dealing With the Ill and Impaired Body
Authors: Leder Drew 
Published: October 2021

Abstract
Encounters with illness, impairment, and aging can disrupt one’s experiential relationship with self, body, others, and world. “Healing” takes place when the individual is able to re-integrate his or her world, even if the condition is not medically curable. Drawing on work in the phenomenology of the body, this article examines a series of eight “healing strategies” individuals employ, each representing a different way of orienting toward the painful or impaired body. One may lean into freeing oneself from the body, through strategies of “refusing,” “ignoring,” “objectifying,” or “transcending” its problems. Conversely, one may choose to embrace the body, through strategies such as “accepting,” “listening,” “befriending,” or “witnessing.” It can be beneficial to have a good number of such coping strategies at one’s disposal, enhancing flexible response to chronic challenges. They also are often used in synergistic or complementary combinations.
Validating the Factor Structure of the Psychosocial Assessment Tool Using Internet-Based Data
Authors: Enlow Paul T , Lewis Amanda M , Scialla Michele A , Hwang Wei-Ting , Kazak Anne E 
Published: October 2021

Abstract

Objective
The Psychosocial Assessment Tool (PAT) is a well-validated, brief screener of family psychosocial risk. Since 2014 a web-based version of the PAT (WebPAT) has been available for use by clinicians and researchers, but the psychometric properties have not been examined. The objective of this article was to examine the factor structure and internal consistency of the WebPAT, which was administered to caregivers of youth with cancer.

Methods
The WebPAT was administered to 1,252 caregivers of youth with cancer across 29 institutions. Confirmatory factor analysis (CFA) was used to examine the factor structure of the WebPAT. Internal consistencies of the total and subscale scores were examined via the Kuder–Richardson 20 coefficient. The distribution of total PAT score across the three risk categories of the Pediatric Psychosocial Preventative Health Model (PPPHM) was also examined.

Results
The CFA supported the original seven-factor structure of the PAT (Family Structure, Social Support, Child Problems, Sibling Problems, Family Problems, Stress Reactions, and Family Beliefs). Internal consistencies were strong for the total PAT score and four subscales (Social Support, Child Problems, Sibling Problems, and Family Problems). The distribution of total PAT scores across PPPHM risk categories was consistent with prior research.

Conclusions
The WebPAT is a psychometrically sound screener of psychosocial risk in families of youth with cancer. Healthcare providers can use the WebPAT to assess families’ psychosocial risk and guide the provision of psychosocial care. Future research should evaluate the implementation of the PAT and identify barriers and facilitators to implementation.
Metagenomic Next-Generation Sequencing for Infectious Disease Diagnosis: A Review of the Literature With a Focus on Pediatrics
Authors: Edward Priya , Handel Andrew S 
Published: October 2021

Abstract
Metagenomic next-generation sequencing (mNGS) is a novel tool for identifying microbial DNA and/or RNA in blood and other clinical specimens. In the face of increasingly complex patients and an ever-growing list of known potential pathogens, mNGS has been proposed as a breakthrough tool for unbiased pathogen identification. Studies have begun to explore the clinical applicability of mNGS in a variety of settings, including endocarditis, pneumonia, febrile neutropenia, osteoarticular infections, and returning travelers. The real-world impact of mNGS has also been assessed through retrospective studies, documenting varying degrees of success and limitations. In this review, we will explore current highlights of the clinical mNGS literature, with a focus on pediatric data where available. We aim to provide the reader with a deeper understanding of the strengths and weaknesses of mNGS and to provide direction toward areas requiring further research.
Pharmacodynamic/pharmacokinetic correlation of optimized ibuprofen nanosuspensions having enhanced anti-inflammatory and antinociceptive activity
Authors: Bandarkar Farzana , Masocha Willias , Nada Aly 
Published: October 2021

Abstract

Objectives
The main objective of this study was to evaluate the antinociceptive and anti-inflammatory activity of ibuprofen (IB) nanoformulations which were developed in our previous study and showed enhanced in-vitro dissolution rate compared with the marketed formulation.

Methods
The in-vivo pharmacodynamic (PD) studies were performed in mice. The antinociceptive effect of the formulations was evaluated using the formalin test, whereas the anti-inflammatory activity was evaluated by measuring oedema caused by formalin test.

Key findings
The optimized formulation exhibited nanosized particles with rapid dissolution compared with IB in water and marketed product. The antinociceptive and anti-inflammatory activity of IB was significantly improved in optimized nanosuspension compared with other formulations. A good correlation was observed between the pharmacokinetic and PD data: nanosuspension &gt; freeze-dried nanoparticles &gt; marketed product &gt; unhomogenized formulation &gt; IB suspension in water. There was a significantly good correlation between percentage inhibition of paw oedema with peak serum concentration (Cmax) and time at which the Cmax is observed (Tmax) but not area under the curve (AUC), whereas there was a good correlation between percentage inhibition of formalin-induced nociception in phase II, but not phase I, with AUC and Cmax but not Tmax.

Conclusions
The development of IB nanoformulation by ultra-homogenization technique improved its dissolution and PD properties.
Endovascular treatment of penetrating vascular injuries
Authors: Cheraghali Roozbeh , Salimi Javad , Omrani Zahra 
Published: October 2021

Abstract
Endovascular treatment of vascular injuries has resulted in reduced operating time, blood loss, hospital mortality and sepsis. The purpose of this study was to evaluate the success and complication rate of the endovascular management of penetrating peripheral vascular injuries during 5 years. In this observational study, the clinical records and imaging features of 22 penetrating trauma injuries of 276 penetrating vascular trauma patients (8%), which were repaired using endovascular stent-grafts or coil embolization, between April 2013 and August 2018, included in the study. The median age of patients was 43 years (Range, 20–78 years). There were 17 stab wounds (77.3%), 2 shotgun war remnants (9.1%) and 2 iatrogenic post-surgical lesions. Eleven stent-grafts (50%) and nine coil embolizations (40.9%) were deployed. Endovascular interventions in the management of peripheral vascular injuries can be efficient in definitive repair, damage control and hemorrhage control in severely ill trauma patients.
Spontaneous gallbladder perforation in patient with COVID-19—a case report and review of literature
Authors: Basukala Sunil , Rijal Sabina , Karki Saurav , Basukala Bikram , Gautam Alok Raj 
Published: October 2021

Abstract
The Coronavirus 2019 disease (COVID-19) originated in Wuhan in China in December 2019 has evolved over the past year in terms of its pathophysiology, clinical presentation, imaging manifestations and management strategies. Though COVID-19 is predominantly a pulmonary illness, it is now established to show widespread extra pulmonary involvement. Gastrointestinal manifestations of COVID-19 are also well known. COVID-19 infection presenting with the involvement of gallbladder is extremely rare in medical literature. Gallbladder perforation should be thought of in COVID-19 patients complaining of with acute abdomen in with acute cholecystitis.
Out of Africa: characterizing the natural variation in dynamic photosynthetic traits in a diverse population of African rice (Oryza glaberrima)
Authors: Cowling Sophie B , Treeintong Pracha , Ferguson John , Soltani Hamidreza , Swarup Ranjan , Mayes Sean , Murchie Erik H 
Published: October 2021

Abstract
African rice (Oryza glaberrima) has adapted to challenging environments and is a promising source of genetic variation. We analysed dynamics of photosynthesis and morphology in a reference set of 155 O. glaberrima accessions. Plants were grown in an agronomy glasshouse to late tillering stage. Photosynthesis induction from darkness and the decrease in low light was measured by gas exchange and chlorophyll fluorescence along with root and shoot biomass, stomatal density, and leaf area. Steady-state and kinetic responses were modelled. We describe extensive natural variation in O. glaberrima for steady-state, induction, and reduction responses of photosynthesis that has value for gene discovery and crop improvement. Principal component analyses indicated key clusters of plant biomass, kinetics of photosynthesis (CO2 assimilation, A), and photoprotection induction and reduction (measured by non-photochemical quenching, NPQ), consistent with diverse adaptation. Accessions also clustered according to countries with differing water availability, stomatal conductance (gs), A, and NPQ, indicating that dynamic photosynthesis has adaptive value in O. glaberrima. Kinetics of NPQ, A, and gs showed high correlation with biomass and leaf area. We conclude that dynamic photosynthetic traits and NPQ are important within O. glaberrima, and we highlight NPQ kinetics and NPQ under low light.