bluuebunny/crossref_metadata_2025_split huggingface dataset:
Differences between macrovascular and microvascular functions in pregnant women with chronic hypertension or preeclampsia: new insights into maternal vascular health
Authors: Kaihara Julyane N. S. , Grepi Okano Hellen Cristiane , Veiga Eduardo Carvalho de Arruda , Tallarico Gustavo Moleiro , Dias-Junior Carlos Alan , Cavalli Ricardo Carvalho , Sandrim Valeria Cristina 
Published: February 2025

IntroductionHypertensive disorders of pregnancy, including chronic hypertension (CH) and preeclampsia (PE), stand as prominent global contributors to maternal and perinatal morbidity and mortality. Endothelial dysfunction plays a central role in the pathophysiology of these conditions. This dysfunction impacts blood flow and the regulation of vascular response, potentially leading to alterations in the remodeling of blood vessels. Nitric oxide bioavailability, a key regulator of vascular tone, is often diminished in endothelial dysfunction, with nitrite levels serving as a surrogate marker. Methods such as pulse wave velocity (PWV) and peripheral arterial tonometry provide valuable insights into vascular health in large and small vessels, respectively, in hypertensive pregnancies. Among these, peripheral arterial tonometry stands out as a less explored technique in research. This study aimed to evaluate potential alterations in the macrovascular arterial stiffness and the microvascular endothelial function among pregnant women diagnosed with CH or PE compared to healthy pregnant (HP) women. Additionally, we aimed to correlate these vascular parameters with demographic and clinical data.MethodsThe study enrolled 24 HP women, 24 with CH during pregnancy, and 24 with PE who underwent evaluations of large-artery stiffness via PWV assessments and peripheral arterial tonometry via natural logarithm of the reactive hyperemia index (lnRHI) assessments.ResultsPatients with CH and PE exhibited higher large-artery stiffness than HP, although the lnRHI values remained comparable across all groups. Furthermore, PWV values demonstrated a direct correlation or tendency toward a positive correlation with systolic and diastolic blood pressures (SBP and DBP) in all groups. However, PWV and nitrite concentrations were not correlated. Notably, microvascular function was positively correlated with SBP and DBP in PE, but not in CH or HP. The correlation between lnRHI and nitrite concentrations was observed in the PE group.ConclusionThus, our findings indicate that, while HDPs have demonstrated increased large-artery stiffness in comparison to HP, the microvasculature analyzed by peripheral arterial tonometry was similar among all three groups. Interestingly, the correlation patterns in the nitrite levels, blood pressure, and microvascular function differed in the PE and CH groups.
An ecological approach to caregiver burnout: interplay of self-stigma, family resilience, and caregiver needs among mothers of children with special needs
Authors: Tang Catherine So-Kum , Yu Isaac Chun-Yeung , Ng Kai-hang , Kwok Helen Sin-Hang 
Published: February 2025

IntroductionUsing an ecological framework, this study investigated how individual perceptions (self-stigma), family dynamics (family resilience), and external support systems (caregiver needs) interacted with each other to impact caregiver burnout among mothers of children with special needs (SN) in Hong Kong.MethodsA total of 250 Chinese mothers of children with SN in Hong Kong completed an online survey.ResultsPearson correlation analyses indicated that high levels of caregiver burnout were significantly related to high levels of self-stigma, high levels of unmet caregiver needs, and low levels of family resilience. Multiple regression analysis revealed significant main effects and a 3-way interaction effect of these three factors on caregiver burnout. The significant 3-way (self-stigma X family resilience X caregiver needs) interaction effect showed that in conditions of low self-stigma, the highest level of caregiver burnout was found among mothers with low family resilience and high caregiver needs. Conversely, in conditions of high self-stigma, the highest level of burnout was observed among mothers with high family resilience and high caregiver needs.DiscussionThe findings of this study underscore the necessity of a holistic and culturally sensitive approach to effectively reducing the caregiving burden among Chinese mothers of children with SN. Addressing caregiver burnout in these mothers requires simultaneous efforts to reduce self-stigma through psychological support, educate families to manage expectations and alleviate pressure, and enhance society resources to meet caregiver needs.
The influence of sensation seeking on college student sports lottery purchasing behavior: a moderated mediation model
Authors: Wang Kanglin , Qiu Fen 
Published: February 2025

ObjectiveThe study aims to explore how sensation seeking relates to college students sports lottery purchasing behavior, mediated by fear of missing out and moderated by perceived risk.MethodsA study surveyed 409 college students using various scales to assess sensation seeking, sports lottery purchasing behavior, fear of missing out, and perceived risk. Data analysis included descriptive stats, t-tests, partial correlations, mediation and moderation effects, and Bootstrap testing to understand the psychological drivers behind sports lottery purchases among students.Results(1) Sensation seeking significantly and positively predicted college students sports lottery purchasing behavior; (2) Fear of missing out played a partial mediating effect in the influence of sensation seeking on college students sports lottery purchasing behavior; (3) Perceived risk had a moderating effect in the second half of the path of the mediating effect of fear of missing out.ConclusionThe study concludes that sensation seeking directly affects college students sports lottery purchasing behavior, mediated by fear of missing out. The mediating effect is moderated by perceived risk, highlighting the complexity of psychological factors in risk-taking behaviors. This insight calls for tailored interventions addressing these multifaceted factors.
Water polo coaches believe they gain an advantage by calling time-out before playing power-play, but is that really true?
Authors: Lupo Corrado , Li Volsi Damiano , Brustio Paolo Riccardo , Ungureanu Alexandru Nicolae 
Published: February 2025

IntroductionThe present study aimed to evaluate the impact of time-out on power-play outcomes both in elite senior and youth matches and in relation to final (margin of victory, MoV) and current (margin of advantage, MoA) match scores (i.e., winning in unbalanced games, MW; winning-draw-losing in close games, W-D-L; losing in unbalanced games, ML).Materials and methodsA total of 97 (seniors, n = 50; youth, n = 47) European Championship matches were analyzed, comparing power-plays preceded or not by a time-out in relation to the following offensive indicators: goal, exclusion, penalty, and no-goal.ResultsThe results reported that both senior and youth levels have been characterized by better power-play outcomes without time-out (higher goals scored: senior, p ≤ 0.01, youth, p ≤ 0.001; and lower “no goal” events: p ≤ 0.01, youth, p ≤ 0.01). Similar trends were observed with respect to the MoV. Specifically, in senior close games, there were both significantly higher goals scored (p ≤ 0.05) and fewer ‘no goal’ events (p ≤ 0.05), and these patterns were also evident among youth losing teams in unbalanced games. Differently, for MoA, both higher goals scored (p ≤ 0.01) and lower “no goal” events (p ≤ 0.01) emerged for senior losing teams in unbalanced games and youth close games (higher goals scored, p ≤ 0.01; and lower “no goal” events, p ≤ 0.05).DiscussionTherefore, the present study demonstrated that time-out tends to limit the success of the following power-play action and that MoV and MoA approaches do not overlap. As a consequence, coaches could benefit from these findings by being more aware of the actual time-out consequences on the following power-play as well as their defensive potentialities when the opponents call time-out.
The impact of high-intensity interval training on anxiety: a scoping review
Authors: Wang Yidan , Zhang Xiaotu , Zhang Ye , Zhang Hongshi 
Published: February 2025

BackgroundIn recent years, high-intensity interval training (HIIT) has gained significant attention due to its efficient use of time. Studies have shown that engaging in regular physical activity can effectively reduce symptoms of anxiety. Given the potential side effects and limitations associated with pharmacological treatments for anxiety disorders, there is a growing interest in exploring non-pharmacological interventions. HIIT, as an alternative approach, offers a promising avenue for managing anxiety without relying on medication. However, the specific efficacy and applicability of HIIT for individuals diagnosed with anxiety disorders have not been systematically summarized in the literature. This scoping review aims to explore the effectiveness of HIIT as an intervention for improving anxiety symptoms, as well as its range of applicability, by synthesizing existing research.MethodsA scoping review methodology was employed to search databases including PubMed, Web of Science, EMbase, and the Cochrane Library. Studies were selected based on predefined criteria: randomized controlled trials (RCTs), cohort studies, and quasi-experimental designs focusing on the improvement of anxiety, using HIIT as the primary intervention. Exclusion criteria included studies with mixed interventions or populations with comorbid conditions. Two independent evaluators screened titles, abstracts, and full texts, extracted data using a pre-tested form, and resolved discrepancies through discussion to ensure consistency and accuracy.ResultsA total of 541 articles were identified, of which 16 met the inclusion criteria for this review. The samples comprised various populations, including healthy subjects, overweight males, prostate cancer patients, etc. Twelve studies indicated that HIIT significantly improves anxiety symptoms, especially for individuals with lower baseline anxiety. The effect was less pronounced in those with higher baseline anxiety. Additionally, the studies suggest that variations in training protocols—such as frequency, intensity, and duration—may influence the extent to which HIIT improves anxiety symptoms.ConclusionsThis study underscores the potential of High-Intensity Interval Training (HIIT) as an effective intervention for reducing anxiety symptoms, especially when tailored to individual baseline characteristics. Variations in training parameters such as frequency, intensity, and duration are critical factors in optimizing HIIT’s effectiveness for mental health benefits.HIIT shows promise as a valuable tool for managing anxiety, with the potential to significantly improve mental health outcomes when implemented with careful consideration of individual differences and protocol variations. This study provides a foundation for refining HIIT protocols and expanding their applicability across diverse populations.
Unlocking potential: innovative “private-non-profit” partnership for empowering children with disabilities in resource-limited settings in Nepal
Authors: Banskota Bibek , Bhusal Rajan , Yadav Prakash Kumar , Baidya Jagdish Lal , Banskota Ashok Kumar 
Published: February 2025

BackgroundPhysical disabilities affect approximately 240 million children globally, with limited access to comprehensive care in resource-constrained settings. In Nepal, an estimated 2% of children under 16 experience physical disabilities, facing significant barriers to healthcare access, education, and social integration. Traditional healthcare models often struggle to provide affordable, accessible, and sustainable care for these children.ObjectivesTo evaluate the effectiveness and sustainability of an innovative private-nonprofit partnership model between the Hospital and Rehabilitation Centre for Disabled Children (HRDC) and B&amp;B Hospital in Nepal, designed to provide comprehensive care for children with physical disabilities in resource-limited settings.MethodsThe study analyzes a 40-year experience implementing a unique healthcare delivery model combining HRDC’s non-profit expertise with B&amp;B Hospital’s private sector resources. The model integrates four key components: identification through mobile camps and community outreach, comprehensive medical treatment, rehabilitation services, and social reintegration programs.ResultsThe partnership achieved a 62% reduction in treatment costs compared to private healthcare institutions. Over 40 years, HRDC has performed more than 55,000 surgeries, benefiting over 116,000 children surgically. The program has distributed 100,000+ assistive devices, raised disability awareness among 1.5 million+ people, and trained over 700 primary rehabilitation therapists. The model’s community-based approach has enabled coverage of all 77 districts in Nepal through rotating mobile clinics.ConclusionThe HRDC-B&amp;B partnership demonstrates that private-nonprofit collaboration can effectively address healthcare barriers for children with physical disabilities in resource-limited settings. The model’s success in combining cost efficiency, quality care, and community integration provides a replicable framework for similar interventions in other developing countries. Key factors for success include diverse funding sources, strong community engagement, and integrated service delivery under one roof.
Association of mental health status with perceived barriers to healthy diet among Bangladeshi adults: a quantile regression-based approach
Authors: Hasan A. B. M. Nahid , Kundu Satyajit , Jahan Ishrat , Basak Tapu , Hasan Mahamudul , Sharif Azaz Bin 
Published: February 2025

IntroductionMaintaining a healthy diet is essential for both physical and mental well-being. This study investigated the association of mental health status with perceived barriers to maintaining healthy diets among Bangladeshi adults.MethodThis cross-sectional study was conducted between January to June 2023 in Bangladesh. A total of 400 adults aged between 18 and 60 years who reside in Dhaka, Chattogram, and Gazipur cities were recruited using a multistage sampling technique. A questionnaire consisting of 12 questions adapted from previous literature was used to assess barriers to healthy diets. Mental health status was measured using the validated DASS-21 scale. A quantile regression-based approach was used to ascertain the association between mental health status and barriers to healthy diets.ResultsThe five most frequently reported barriers to a healthy diet were the use of junk food as a reward or treat (56.25%), difficulty in controlling eating habits when with friends (56%), the cost of healthy food (44.5%), difficulty in taking healthy food at work (46.5%), and difficult to stay motivated to eat healthy food (25%). The study found that gender, marital status, living arrangement, working hours, and family monthly income were significantly associated with perceived barriers to healthy diets. Mental health status was observed to be associated with barriers to healthy diet scores. Depression (β =0.34, 95% CI: 0.17 to 0.51) and anxiety (β =0.14, 95% CI: 0.01 to 0.28) were significantly associated with perceived barrier scores at the 50th quantile. Stress was also significantly associated with perceived barrier scores at the 10th (β =0.18, 95% CI: 0.09 to 0.27) and the 25th quantiles (β =0.12, 95% CI: 0.03 to 0.21).ConclusionIn light of the findings, it is imperative to prioritize the advocacy of policies that integrate mental health services and stress management strategies into public health initiatives.
The impact of health literacy on smoking patterns among male residents: insights from Ningbo City
Authors: Tao Zhenbo , Xu Qianqian , Zhu Yingying , Jin Qiuyan , Chen Lingwei , Ding Shige , Zhao Shuning , Dong Ying 
Published: February 2025

BackgroundThis study examined the associations between health literacy and smoking behaviors among residents in Ningbo City, Zhejiang Province, China, investigating both the impact of health literacy on smoking prevalence and intensity, and its potential role in smoking cessation interventions.MethodsThis cross-sectional study analyzed data from 2,948 male participants in the 2023 Health Literacy and Tobacco Use Surveillance Survey. We applied logistic regression models and restricted cubic spline analyses to assess the association between health literacy and smoking behaviors, adjusting for demographic characteristics, socioeconomic factors, and self-reported health status.ResultsOur findings indicate that higher levels of health literacy are associated with significantly lower rates of smoking (OR = 0.643, 95%CI = 0.528, 0.783) and daily cigarette consumption (β = −1.938, 95%CI = −3.649, −0.228). Non-smokers with higher health literacy were more likely to discourage others from smoking (OR = 1.464, 95%CI = 1.096, 1.955), underscoring health literacy’s crucial role in smoking prevention and control. A nonlinear relationship between health literacy and smoking behavior was identified.ConclusionHealth literacy significantly influences smoking behavior, with higher literacy levels associated with reduced smoking prevalence and intensity. These findings support incorporating health literacy enhancement into comprehensive smoking cessation strategies.
Isolation and Characterization of Komagataeibacter piraceti sp. nov. and Novacetimonas labruscae sp. nov.: Two Novel Microaerobic Cellulose-Producing Acetic Acid Bacteria from Vinegars
Authors: Karničnik Bernarda , Accetto Tomaž , Fanedl Lijana , Jugović Igor , Trček Janja 
Published: February 2025

The genera Komagataeibacter and Novacetimonas comprise industrially important species that produce various foods, nanocellulose, acetan-like polysaccharides, enantioselective sugars, and other valuable products. Here, we describe two novel strains, Hr1 and Jurk4, isolated from pear and apple-grape organic vinegars that showed very high (≥99.39%) 16S rRNA gene sequence identities to species of the Komagataeibacter and Novacetimonas genera, respectively. However, analysis of the 16S-23S rRNA gene internal transcribed spacer (ITS) sequences revealed only 92.6% sequence identity between the Hr1 strain and its closest relative, Komagataeibacter sucrofermentans LMG 18788T, and 93.8% sequence identity between the Jurk4 strain and its closest relative, Novacetimonas cocois JCM 31140T. Further whole-genome analysis showed for both strains an average nucleotide identity (ANI) below 94% and an in silico DNA–DNA hybridization (dDDH) value of less than 70% to their closest species, supporting their distinction as novel species. The strain Hr1 can be phenotypically differentiated from its closest Komagataeibacter species based on its ability to utilize (NH4)2SO4 as the sole nitrogen source in Asai medium with D-glucose and its inability to grow with 1-propanol as a sole carbon source. The strain Jurk4 can be differentiated from other Novacetimonas type strains based on its ability to produce 5-keto-D-gluconic acid, its growth in a medium with glycerol as the sole carbon source, and its inability to grow in an Asai medium with D-glucose. Both strains produce cellulose and possess clusters for acetane-like polysaccharide production, although of different types, which makes them industrially relevant. Based on these findings, we propose Komagataeibacter piraceti sp. nov. Hr1T (=ZIM B1167T = LMG 33628T) and Novacetimonas labruscae sp. nov. Jurk4T (=ZIM B1166T = LMG 33630T) as two novel members of the acetic acid bacteria group.
Pattern Recognition untuk Klasifikasi Penyakit Kanker Kulit menggunakan Artificial Intelligence (AI)
Authors: Sari Handayani Pusadan  , Suriyanti  , Andriar Makahrun  , Mohammad Yazdi  , Zakiani Sakka  
Published: February 2025

This research aims to classify skin cancer images using an artificial intelligence method called Convolutional Neural Networks (CNN). The study focuses on classifying skin cancer into 7 categories, using data from the International Skin Imaging Collaboration (ISIC). We employed the CNN algorithm to train the model, which involved learning features, classifying images, and optimizing the model. To evaluate the model's performance, we experimented with different training data proportions (70%, 80%, and 90%), dropout rates (0.5, 0.6, 0.7, and 0.8), and batch sizes (8, 16, 32, 64). The best results were achieved with 80% of the data for training, a dropout rate of 0.4, and a batch size of 16, resulting in an accuracy of 83.22%.

ABSTRAK
Penelitian ini bertujuan untuk mengimplementasikan metode kecerdasan buatan melalui algoritma Convolution Neural Network (C-NN) untuk mengklasifikasikan citra kanker kulit. Objek pada penelitian ini adalah klasifikasi kanker kulit dengan berdasarkan 7 kategori kanker kulit, sedangkan Data yang digunakan oleh peneliti adalah data yang bersumber dari The International Skin Imaging Collaboration (ISIC). Metode yang digunakan peneliti adalah Algoritma Convolutional Neural Networks (CNN). Pada data training dilakukan pembelajaran fitur, klasifikasi, dan optimum model, dimana proses ini merupakan implementasi algoritma yang digunakan. Skenario pengujian dengan indikator skenario pengujian yaitu pembagian data training 70%, 80%, dan 90%, inisialisasi Dropout layer bernilai 0.5, 0.6, dan 0.7, dan 0,8 dan Batchsize bernilai 8, 16, 32, 64. Kesimpulan dari Penelitian ini adalah mendapatkan model terbaik dengan nilai akurasi 83.22% dari komposisi data Taining 80%, Dropout 0.4 dan Batchsize 16.