bluuebunny/crossref_metadata_2025_split huggingface dataset:
Scheduling the periodic delivery of liquefied petroleum gas tank with time window by using artificial intelligence approaches: An example in Taiwan
Authors: Hsieh Yi-Chih , You Peng-Sheng , Chen Cheng-Sheng 
Published: September 2021

Introduction In Taiwan, liquefied petroleum gas tank users have to call a gas company to deliver a full liquefied petroleum gas tank when their tank is out of gas. The calls usually congest in the cooking time and the customers have to wait for a long time for a full liquefied petroleum gas tank. Additionally, allocating manpower is difficult for the gas company. Objectives A strategy of periodic delivery for gas companies was presented to deliver liquefied petroleum gas tanks in advance and charge the gas fee based on the weight of returned tanks. Additionally, a new encoding scheme was proposed and embedded into three evolutionary algorithms to solve the nondeterministic polynomial-hard problem. The objective of the problem is to minimize the total traveling distance of the vehicle such that the delivery efficiency of tanks increases and the waiting time of customer decreases. Methods A new encoding scheme was presented to convert any random sequence of integers into a solution of the problem and embedded into three evolutionary algorithms, namely, immune algorithm, genetic algorithm, and particle swarm optimization, to solve the delivery problem. Additionally, the encoding scheme can be used to different frequency types of demand based on customers’ requests. Results Numerical results, including a practical example in Yunlin, Taiwan, were provided to show that the adopted approaches can significantly improve the efficiency of delivery. Conclusions The periodic delivery strategy and the new encoding scheme can effectively solve the practical problem of liquefied petroleum gas tank in Taiwan.
Pediatric onset lupus nephritis in western India—is it different from the rest of the country?
Authors: Mittal Aliza , Bamnawat Harshita , Nalwa Aasma , Vishwajeet Vikarn , Kumar Prawin , Didel Siyaram , Goel Akhil Dhanesh , Singh Kuldeep 
Published: September 2021

Aim To determine the clinicopathological characteristics and outcomes of children diagnosed with lupus nephritis in a tertiary hospital in western Rajasthan and compare it with the data available from other parts of India. Material and methods: A retrospective review of children presenting to a tertiary care center in western Rajasthan, India, with a diagnosis of pediatric Systemic Lupus Erythematosus (p SLE), between July 2017 and July 2020 was done. Comparisons of pediatric lupus in western India to other parts of country were done. Results 19 children with SLE with Renal involvement were enrolled and followed up. The median age at presentation was 15 years (IQR-16–9.5) (73% females). 8/19 (42%) children presented with AKI, of which 62% children presented as rapidly progressive renal failure. Six (37.5%) patients required dialysis at presentation. 84.21% of children were evaluated with renal biopsy, 16 biopsies were done in 19 children, among which class II, III, and IV lupus nephritis were reported in 21%,42%, and 35% respectively(4 crescentic). Antiphospholipid antibodies were positive in 8/15(53%), children which is much higher than a reported incidence of 30% in other Indian studies. Ten patients (52%) had neurological involvement, with seizures being the most common form of presentation (60%). Seven patients (36%) developed hepatitis. We noted many uncommon presentations in the small group like Autoimmune Pancreatitis, Mononeuritis multiplex, and peripheral digital gangrene. Cyclophosphamide was used in 10 out of 19 patients for inducing remission with class 3 and 4 nephritis and MMF in 8 children. 55% patients attained remission (after completing induction), of which 4 relapsed during the follow up. Four patients were lost to follow-up. A total of 27% patients died and 10% patients developed end stage renal failure. It was seen that those who died had more cardiac and neurological involvement at presentation, higher grade of proteinuria, lower GFR, and need for dialysis at admission. Conclusion: We found a more severe form of clinical manifestation in pediatric SLE patients at the time of the first presentation in the form of severe renal and extrarenal manifestation compared to other parts of the country.
A Prospective Study on Type-2 Diabetic Complications and Efficacy of Integrated Yoga: A Pan India 2017
Authors: Patil Suchitra S. , Raghuram Nagarathna , Singh Amit , Rajesh S. K. , Ahmed Sabzar , Hongasandra Nagendra 
Published: September 2021

Background: Type 2 diabetes (T2DM) contributes to high mortality and morbidity because of its major complications related to kidney, heart, brain, and eyes. It also poses a high risk for mortality because of COVID-19. Studies suggest the possible implications of Yoga in delaying or attenuating such complications. Methodology: This was a pan-India multi centered cluster-randomized (4 level) two-armed trial in the rural and urban population of all populous states of India. Data were obtained using mobile app in all adults in the household of the selected clusters. Results: We report the diabetes related complications in 16623 adults (48% males, 52% females) from 65 districts (1 in 10 districts, 2011 census) of 29 (out of 35) states and Union Territories of India; mean age was 48.2 ± 12.46 years. Out of this 40% lived in rural and 62% in urban locations. In high risk diabetes individuals (scored ≥ 60 points on Indian diabetes risk score key), 18.0% had self-reported history of (peripheral neuropathy, 6.1% had h/o major strokes, 5.5% had minor strokes (transient ischemic episodes), 18.1% had lower limb claudication, 20.5% leg ulcers, 4.4% had h/o cardiac surgery, 4.8% angioplasty, and 15.1% had diabetes retinopathy. Complications were higher in rural than in urban areas, higher in people with extended duration of diabetes. Integrated yoga module for three months (one hour daily) showed significantly better reduction in symptoms related to complications as compared to control group ( P < .001) Conclusion: The alarming high prevalence of complications in diabetes population calls for urgent action, where yoga may show the benefits in reduction of symptoms of complications.
Sleep Patterns of Resident Physicians and the Effect of Heartfulness Meditation
Authors: Thimmapuram Jayaram , Pargament Robert , Tredici Sonya Del , Bell Theodore , Yommer Deborah , Daoud Dana , Powell Frankie , Madhusudhan Divya K. 
Published: September 2021

Background: Medical residents are vulnerable to poor sleep quality due to intense work shifts and academic load. Studies objectively quantified with sleep quantity and quality among resident physicians are limited. Meditation techniques have been shown to improve sleep but are rarely studied in this population. The aim of the present study is to evaluate sleep patterns of internal medicine residents and the effect of a structured Heartfulness meditation program to improve sleep quality. Methods: A total of 36 residents participated in a pre–post cohort study from January 2019 through April 2019. Sleep was monitored during a one-week outpatient rotation with two validated assessment tools, namely consensus sleep diary and actigraphy. After four intervening weeks, when the residents returned to the same rotation, Heartfulness meditation was practiced and the same parameters were measured. At the end of the study period, an anonymous qualitative feedback survey was collected to assess the feasibility of the intervention. Results: All 36 residents participated in the study (mean age 31.09 years, SD 4.87); 34 residents (94.4%) had complete pre–post data. Consensus sleep diary data showed decreased sleep onset time from 21.03 to 14.84 min ( P = .01); sleep quality and restfulness scores increased from 3.32 to 3.89 and 3.08 to 3.54, respectively ( P < .001 for both). Actigraphy showed a change in sleep onset time from 20.9 min to 14.5 min ( P = .003). Sleep efficiency improved from 83.5% to 85.6% ( P = .019). Wakefulness after initial sleep onset changed from 38.8 to 39.9 min ( P = .682). Sleep fragmentation index and the number of awakenings decreased from 6.16 to 5.46 ( P = .004) and 41.71 to 36.37 ( P = .013), respectively. Conclusions: Residents obtained nearly 7 h of sleep during outpatient rotation. Findings suggest a structured Heartfulness meditation practice to be a feasible program to improve subjective sleep onset time and several objective measures among resident physicians.
Female Labour Force Participation in India: Insights Through Time Use Survey
Authors: Srija A. , Vijay Shirke Shrinivas 
Published: September 2021

Labour market employment statistics covers less than 50% of all the work performed each week, and on a gender basis, the coverage is 75% of men’s work and 33% of women’s work (Ironmonger,1999). The Periodic Labour Force Survey (2018-19) results show a gap of 35.4% and 40.6% between male–female LFPR (usual status: principal + subsidiary). About 42.5% of the women (age group 15+ years) are engaged in domestic duties only while 14.2% engaged in domestic duties are also engaged in free collection of goods (vegetables, roots, firewood, cattle feed, etc.), sewing, tailoring, weaving, etc. for household consumption. As the burden of unpaid domestic duties falls largely on the females, their activities go uncaptured. It is, therefore, important to understand the time disposition of women and their burden of work so as to help informed policy formulation inclusive of women. Using the results of the Time Use Survey (2019) and the Periodic Labour Force Surveys, this study tries to better understand the gamut of paid and unpaid economic activities undertaken by women in India and aims to get better insights into the factors affecting the female labour force participation in rural and urban India. This study reflects that the double burden of unpaid domestic and caregiving activities is prevalent irrespective of the education level of the women, the income levels of the household and is equally affecting women in rural as well as urban Indian households. The findings support the fact that the predominance of time disposition on non-SNA activities negatively affects the choice of economic activities undertaken by women and there is a need to address this divide of time disposition of men and women in non-SNA activities in order to increase the female Labour Force Participation. Using cross country comparison of the G20 countries, it is observed that distribution of domestic and caregiving activities among men and women has a positive impact on the labour force participation of women. While it may be difficult to quantify the entire gamut of unpaid domestic and care giving activities into the SNA and come with improved GDP estimate, ways to reduce the burden of unpaid domestic duties can always be thought of as mentioned in the section on policy interventions. JEL Classification: J220
Alveolar Cleft Reconstruction Using Double Iliac Corticocancellous Bone Plates Grafting Technique in Mixed Dentition Phase
Authors: Omara Mohammed , Ahmed Mamdouh , Shawky Mohamed , Ali Sherif 
Published: September 2021

Objective The primary goal of maxillary alveolar cleft reconstruction in patients with cleft lip/palate at the phase of mixed dentition is to build bone in the cleft area which in turn allows closure of the oronasal fistula, establishes arch continuity, and improve maxillary stability. This study aimed to evaluate the double iliac corticocancellous bone plates grafting technique for initial alveolar cleft grafting. Design This prospective study was conducted on 12 consecutive patients with unilateral complete alveolar cleft and previous cleft lip and palate corrective surgery. Intervention For all patients, the iliac crest graft was harvested and cut into 2 cortical bone plates and adapted labially and palatally. Both plates were fixed with screws then the gap between the 2 plates was filled with cancellous bone. The grafted side was compared to the contralateral side 9 months postoperatively regarding labio-palatal alveolar width and bone density, while the 9 months postoperative graft height was compared to the immediate postoperative height using computed tomography scans. Results All grafted sides showed similarity to the contralateral sides regarding both alveolar width and bone density with minimal crestal bone resorption. Conclusion The double iliac corticocancellous bone plate grafting technique seems to be a reliable method for alveolar cleft reconstruction with adequate bone quality and contour.
Preliminary Efficacy and Acceptability of an Online Exercise and Nutrition Workplace Wellness Program: A Brief Report
Authors: SantaBarbara Nicholas , Rezai Roxana , Terry Elisa , Shedd Kelly , Comulada W. Scott 
Published: September 2021

Background Workplace wellness programs (WWP) offer physiological and psychological benefits to employees and financial and productivity benefits to employers. However, the COVID-19 pandemic has prevented in-person sessions and has required WWP’s to transition to online platforms. The purpose of this brief report was to assess the preliminary feasibility, acceptability, and efficacy of a mobile version of the Bruin Health Improvement Program (BHIP mobile) WWP. Methods Participants virtually attended (i.e., via Zoom) twice weekly physical activity sessions and a once weekly nutrition seminar for 10-weeks with the option of a 30-minute one-on-one consultation with a registered dietician. Demographics, anthropometric indices, stress, muscular endurance, and aerobic fitness were assessed at baseline and follow-up. All analyses were conducted in SPSS v. 27. Results Twenty-seven participants (96% female) enrolled and 13 (100% female) completed the 10-week program. There were significant reductions in bodyweight ( p < .01) and body mass index ( p < .02) but not stress ( p > .05), and significant increases in muscular endurance ( p < .01) but not aerobic fitness ( p > .05). Overall, BHIP mobile appears to be acceptable to participants but logistical concerns such as inconsistent internet connection was noted as potential downfalls. Conclusions/Applications to Practice Improvements in health outcome among completers of a mobile WWP were promising. Completer feedback highlighted program strengths as the flexibility and comfort of attending exercise sessions and nutrition classes from home. Future versions of the program will allocate resources to improve completion and expand appeal for men and women.
Titanium Cervical Cage Subsidence: Postoperative Computed Tomography Analysis Defining Incidence and Associated Risk Factors
Authors: Pinter Zachariah W. , Reed Ryder , Townsley Sarah E. , Mikula Anthony L , Dittman Lauren , Xiong Ashley , Skjaerlund Jonathan , Michalopoulos Giorgos D. , Currier Bradford , Nassr Ahmad , Fogelson Jeremy L. , Freedman Brett A. , Bydon Mohamad , Kepler Christopher K. , Wagner Scott C , Elder Benjamin D. , Sebastian Arjun S. 
Published: September 2021

Study Design Retrospective cohort study Objective Substantial variability in both the measurement and classification of subsidence limits the strength of conclusions that can be drawn from previous studies. The purpose of this study was to precisely characterize patterns of cervical cage subsidence utilizing computed tomography (CT) scans, determine risk factors for cervical cage subsidence, and investigate the impact of subsidence on pseudarthrosis rates. Methods We performed a retrospective review of patients who underwent one- to three-levels of anterior cervical discectomy and fusion (ACDF) utilizing titanium interbodies with anterior plating between the years 2018 and 2020. Subsidence measurements were performed by two independent reviewers on CT scans obtained 6 months postoperatively. Subsidence was then classified as mild if subsidence into the inferior and superior endplate were both ≤2 mm, moderate if the worst subsidence into the inferior or superior endplate was between 2 to 4 mm, or severe if the worst subsidence into the inferior or superior endplate was ≥4 mm. Results A total of 51 patients (100 levels) were included in this study. A total of 48 levels demonstrated mild subsidence (≤2 mm), 38 demonstrated moderate subsidence (2-4 mm), and 14 demonstrated severe subsidence (≥4 mm). Risk factors for severe subsidence included male gender, multilevel constructs, greater mean vertebral height loss, increased cage height, lower Taillard index, and lower screw tip to vertebral body height ratio. Severe subsidence was not associated with an increased rate of pseudarthrosis. Conclusion Following ACDF with titanium cervical cages, subsidence is an anticipated postoperative occurrence and is not associated with an increased risk of pseudarthrosis.
List of Theses in Foreign Missions and Related Subjects Accepted during the Academic Year 1955–1956
Authors: Person Laura 
Published: September 2021

The compiler wishes to express deep gratitude to the professors of missions in 59 schools and seminaries for the reports which have made possible the compilation of the following list of dissertations and theses. No theses were written in 25 of the schools from which reports were received. The annotations following the theses are by the professors who reported them. Neither compiler nor editor has examined these theses or passed judgment upon them. The professors making the reports have indicated that each particular thesis is related to foreign missions or, in a few instances, to home missions. It is assumed that such is the case where no annotation has been given. Inquiries concerning a title should be addressed to the school concerned and not to the Missionary Research Library, An index to the theses will be found on paga 9.
Veterans’ Interpretation of Diabetes Distress in Diabetes Self-Management: Findings From Cognitive Interviews
Authors: Lewinski Allison A. , Shapiro Abigail , Bosworth Hayden B. , Crowley Matthew J. , McCant Felicia , Howard Teresa , Jeffreys Amy S. , McConnell Eleanor , Tanabe Paula , Barcinas Susan , Coffman Cynthia J. , King Heather A. 
Published: September 2021

Purpose The purpose of this project was to identify additional facets of diabetes distress (DD) in veterans that may be present due to the veteran’s military-related experience. Methods The study team completed cognitive interviews with veterans with type 2 diabetes mellitus (T2DM) to examine how they answered the Diabetes Distress Scale (DD Scale), a tool that assesses DD. The DD Scale was used because of its strong associations with self-management challenges, physician-related distress, and clinical outcomes. Results The veterans sample (n= 15) was 73% male, mean age of 61 (SD = 8.6), 53% Black, 53% with glycosylated hemoglobin level <9%, and 67% with prescribed insulin. The DD Scale is readily understood by veterans and interpreted. Thematic analysis indicated additional domains affecting DD and T2DM self-management, including access to care, comorbidities, disruptions in routine, fluctuations in emotions and behaviors, interactions with providers, lifelong nature of diabetes, mental health concerns, military as culture, personal characteristics, physical limitations, physical pain, sources of information and support, spirituality, and stigma. Conclusions This study describes how a veteran’s military experience may contribute to DD in the context of T2DM self-management. Findings indicate clinicians and researchers should account for additional domains when developing self-management interventions and discussing self-management behaviors with individuals with T2DM.
A novel 3D culture model recapitulates primary FL B-cell features and promotes their survival
Authors: Lamaison Claire , Latour Simon , Hélaine Nelson , Le Morvan Valérie , Saint-Vanne Julien , Mahouche Isabelle , Monvoisin Céline , Dussert Christelle , Andrique Laëtitia , Deleurme Laurent , Dessauge Elise , Pangault Céline , Baulande Sylvain , Legoix Patricia , Seffals Marine , Broca-Brisson Léa , Alessandri Kévin , Carlotti Martina , Soubeyran Pierre , Merlio Jean-Philippe , Mourcin Frédéric , Nassoy Pierre , Recher Gaëlle , Tarte Karin , Bresson-Bepoldin Laurence 
Published: September 2021

Abstract
Non-Hodgkin B-cell lymphomas (B-NHL) mainly develop within lymph nodes as aggregates of tumor cells densely packed with their surrounding microenvironment, creating a tumor niche specific to each lymphoma subtypes. In vitro preclinical models mimicking biomechanical forces, cellular microenvironment, and 3D organization of B-cell lymphomas remain scarce, while all these parameters are key determinants of lymphomagenesis and drug resistance. Using a microfluidic method based on cell encapsulation inside permeable, elastic, and hollow alginate microspheres, we developed a new tunable 3D model incorporating lymphoma B cells, extracellular matrix (ECM), and/or tonsil stromal cells (TSC). Under 3D confinement, lymphoma B cells were able to form cohesive spheroids resulting from overexpression of ECM components. Moreover, lymphoma B cells and TSC dynamically formed self-organized 3D spheroids favoring tumor cell growth. 3D culture induced resistance to the classical chemotherapeutic agent doxorubicin, but not to the BCL2 inhibitor ABT-199, identifying this approach as a relevant in vitro model to assess the activity of therapeutic agents in B-NHL. RNA-sequence analysis highlighted the synergy of 3D, ECM, and TSC in upregulating similar pathways in malignant B cells in vitro than those overexpressed in primary lymphoma B cells in situ. Finally, our 3D model including ECM and TSC allowed long-term in vitro survival of primary follicular lymphoma B cells. In conclusion, we propose a new high-throughput 3D model mimicking lymphoma tumor niche and making it possible to study the dynamic relationship between lymphoma B cells and their microenvironment and to screen new anti-cancer drugs.
Anti–IL-6 cytokine treatment has no impact on elevated hematocrit or splenomegaly in a polycythemia vera mouse model
Authors: Baldauf Conny K. , Müller Peter , Haage Tobias R. , Adam-Frey Stephanie , Lokau Juliane , Garbers Christoph , Fischer Thomas 
Published: September 2021

Abstract
Somatic mutations in JAK2, MPL and Calreticulin and inflammation play a key role in pathophysiology of chronic myeloproliferative neoplasia (CMN). One of the most prominent cytokines elevated in serum of Polycythemia vera patients is interleukin-6 (IL-6). Currently, it is being discussed whether suppression of inflammation by anti-cytokine approaches as anti-IL-6 treatment may be therapeutically useful in CMN. We here sought to investigate the efficacy of anti-IL-6 treatment on inflammatory cytokines, hematocrit and splenomegaly in CMN like disease. JAK2-V617F knock-in mice (JAK2+/V617F) were treated for three weeks with anti-IL-6 antibody (Ab) or IgG-control. Upon anti-IL-6 Ab treatment, serum levels of CXCL2 and CXCL10 were significantly reduced. In addition, CXCL1, CCL11, M-CSF, G-CSF, IL-17, IL-12p40 and CCL2 were reduced by a factor of 0.3 -- 0.8. Partly, this was also achieved by applying high-dose IgG. Hematocrit, erythrocyte and leukocyte counts were elevated in JAK2+/V617F mice but were not reduced by anti-IL6 Ab treatment. In addition, there was no apparent amelioration of splenomegaly and spleen histopathology. In conclusion, anti-IL-6 Ab treatment did not result in improvement of hematological disease parameters but was shown to modulate the serum cytokine signature.