bluuebunny/crossref_metadata_2025_split huggingface dataset:
„Everything was very neat“: Abject Art zwischen Kunstgeschichte und Politik
Authors: Zimmermann Anja 
Published: October 2021

ZusammenfassungDer Beitrag beleuchtet die Rezeption von Abject Art in der Kunstgeschichte und darüber hinaus. Als Kategorie, die die Kunstwissenschaft und -kritik ab den 1980er-Jahren den Schriften der französischen Psychoanalytikerin Julia Kristeva entnahm, diente sie der Kennzeichnung von Kunstwerken, die u. a. mit Repräsentationen des Körpers arbeiteten, die klassischen Idealen widersprachen. Verweise auf Verletzungen, Traumata, aber auch Körperflüssigkeiten und -grenzen waren Themen dieser Arbeiten oder wurden an ihrem Beispiel aus ästhetischer Sicht kritisch analysiert. Besonderes Augenmerk legt der Text auf politische Reaktionen auf Kunstwerke der Abject Art, die als „obszön“, „abstoßend“ oder „ekelhaft“ beschrieben und damit abgewehrt werden. Der Beitrag verdeutlicht an konkreten Beispielen, vornehmlich aus den USA, wie die künstlerischen Strategien, etwa die Verwendung bestimmter Werktitel, eine Rezeption der Werke als abjekt in Gang setzen und wie umgekehrt aber auch Werke, die bei ihrer Entstehung nicht in Bezug zu abjekten Themen gesetzt wurden, später als abjekt gedeutet wurden.
Prevalence and comparisons of alcohol, candy, energy drink, snack, soda, and restaurant brand and product marketing on Twitch, Facebook Gaming and YouTube Gaming
Authors: Edwards Caitlyn G , Pollack Catherine C , Pritschet Sara J , Haushalter Keally , Long John W , Masterson Travis D 
Published: October 2021

AbstractObjective:To compare and evaluate the prevalence of food and beverage marketing on the livestreaming platforms Twitch, Facebook Gaming and YouTube Gaming, as well as examine growth of food and beverage marketing on these platforms over a 17-month period of data collection.Design:Cross-sectional data were analysed across three livestreaming platforms and six food and beverage categories: alcohol, candy, energy drinks, snacks, sodas and restaurants.Setting:Stream titles of livestreamed events as well as corresponding hours watched on Twitch, Facebook Gaming and YouTube Gaming.Participants:None.Results:There were significant differences between the use of food and beverage brand mentions in stream titles across all three studied platforms (P < 0·05), as well as hours watched across platforms (P < 0·05). Energy drinks dominated food and beverage brand mentions across platforms, followed by restaurants, soda and snacks. All platforms demonstrated growth over the 17-month data collection period. Post-hoc analyses revealed that the COVID-19 pandemic impacted both immediate and sustained growth across all platforms, with the greatest impact observed on the Twitch platform.Conclusions:Food and beverage marketing as measured through stream titles is widely prevalent across the three most popular livestreaming platforms, particularly for energy drinks. Food marketing on these platforms experienced growth over the past 17 months which was accelerated substantially by the COVID-19 pandemic. Future work should assess the sustained impact this growth may have on marketing practices and eating behaviour.
Energetic Intracloud Lightning in the RELAMPAGO Field Campaign
Authors: Antunes de Sá A. L. , Marshall R. , Deierling W. 
Published: October 2021

AbstractA particular strength of lightning remote sensing is the variety of lightning types observed, each with a unique occurrence context and characteristically different emission. Distinct energetic intracloud (EIC) lightning discharges—compact intracloud lightning discharges (CIDs) and energetic intracloud pulses (EIPs)—produce intense RF radiation, suggesting large currents inside the cloud, and they also have different production mechanisms and occurrence contexts. A Low‐Frequency (LF) lightning remote sensing instrument array was deployed during the RELAMPAGO field campaign in west central Argentina, designed to investigate convective storms that produce high‐impact weather. LF data from the campaign can provide a valuable data set for researching the lightning context of EICs in a variety of subtropical convective storms. This paper describes the production of an LF‐CID data set in RELAMPAGO and includes a preliminary analysis of CID prevalence. Geolocated lightning events and their corresponding observed waveforms from the RELAMPAGO LF data set are used in the classification of EICs. Height estimates based on skywave reflections are computed, where prefit residual data editing is used to improve robustness against outliers. Even if EIPs occurred within the network, given the low number of very high‐peak current events and receiver saturation, automatic classification of EIPs may not be feasible using this data. The classification of CIDs, on the other hand, is straightforward and their properties, for both positive and negative polarity, are investigated. A few RELAMPAGO case studies are also presented, where high variability of CID prevalence in ordinary storms and high‐altitude positive CIDs, possibly in overshooting tops, are observed.
Prenatal phenotype of PNKP-related primary microcephaly associated with variants affecting both the FHA and phosphatase domain
Authors: Neuser Sonja , Krey Ilona , Schwan Annemarie , Abou Jamra Rami , Bartolomaeus Tobias , Döring Jan , Syrbe Steffen , Plassmann Margit , Rohde Stefan , Roth Christian , Rehder Helga , Radtke Maximilian , Le Duc Diana , Schubert Susanna , Bermúdez-Guzmán Luis , Leal Alejandro , Schoner Katharina , Popp Bernt 
Published: October 2021

AbstractBiallelic PNKP variants cause heterogeneous disorders ranging from neurodevelopmental disorder with microcephaly/seizures to adult-onset Charcot–Marie–Tooth disease. To date, only postnatal descriptions exist. We present the first prenatal diagnosis of PNKP-related primary microcephaly. Pathological examination of a male fetus in the 18th gestational week revealed micrencephaly with extracerebral malformations and thus presumed syndromic microcephaly. A recessive disorder was suspected because of previous pregnancy termination for similar abnormalities. Prenatal trio-exome sequencing identified compound heterozygosity for the PNKP variants c.498G>A, p.[(=),0?] and c.302C>T, p.(Pro101Leu). Segregation confirmed both variants in the sister fetus. Through RNA analyses, we characterized exon 4 skipping affecting the PNKP forkhead-associated (FHA) and phosphatase domains (p.Leu67_Lys166del) as the predominant effect of the paternal c.498G>A variant. We retrospectively investigated two unrelated individuals diagnosed with biallelic PNKP-variants to compare prenatal/postnatal phenotypes. Both carry the splice donor variant c.1029+2T>C intrans with a variant in the FHA domain (c.311T>C, p.(Leu104Pro); c.151G>C, p.(Val51Leu)). RNA-seq showed complex splicing for c.1029+2T>C and c.151G>C. Structural modeling revealed significant clustering of missense variants in the FHA domain with variants generating structural damage. Our clinical description extends the PNKP-continuum to the prenatal stage. Investigating possible PNKP-variant effects using RNA and structural modeling, we highlight the mutational complexity and exemplify a PNKP-variant characterization framework.
Nerve-specific extracellular matrix hydrogel promotes functional regeneration following nerve gap injury
Authors: Meder T. , Prest T. , Skillen C. , Marchal L. , Yupanqui V. T. , Soletti L. , Gardner P. , Cheetham J. , Brown B. N. 
Published: October 2021

AbstractNerve transection requires surgical intervention to restore function. The standard of care involves coaptation when a tension-free repair is achievable, or interposition of a graft or conduit when a gap remains. Despite advances, nerve gap injury is associated with unsatisfactory recovery. This study investigates the use of a decellularized, porcine nerve-derived hydrogel filler (peripheral nerve matrix, PNM) for conduits in an 8 mm rat sciatic nerve gap model. The decellularized tissue maintained multiple nerve-specific matrix components and nerve growth factors. This decellularized tissue was used to formulate hydrogels, which were deployed into conduits for nerve gap repair. Nerve recovery was assessed up to 24 weeks post injury by gait analysis, electrophysiology, and axon counting. Deployment of PNM within conduits was shown to improve electrophysiologic response and axon counts compared with those of empty conduit controls. These results indicate that PNM has potential benefits when used as a filler for conduits in nerve gap injuries.
Analysis of the Breakthrough Listen signal of interest blc1 with a technosignature verification framework
Authors: Sheikh Sofia Z. , Smith Shane , Price Danny C. , DeBoer David , Lacki Brian C. , Czech Daniel J. , Croft Steve , Gajjar Vishal , Isaacson Howard , Lebofsky Matt , MacMahon David H. E. , Ng Cherry , Perez Karen I. , Siemion Andrew P. V. , Webb Claire Isabel , Zic Andrew , Drew Jamie , Worden S. Pete 
Published: October 2021

AbstractThe aim of the search for extraterrestrial intelligence (SETI) is to find technologically capable life beyond Earth through their technosignatures. On 2019 April 29, the Breakthrough Listen SETI project observed Proxima Centauri with the Parkes ‘Murriyang’ radio telescope. These data contained a narrowband signal with characteristics broadly consistent with a technosignature near 982 MHz (‘blc1’). Here we present a procedure for the analysis of potential technosignatures, in the context of the ubiquity of human-generated radio interference, which we apply to blc1. Using this procedure, we find that blc1 is not an extraterrestrial technosignature, but rather an electronically drifting intermodulation product of local, time-varying interferers aligned with the observing cadence. We find dozens of instances of radio interference with similar morphologies to blc1 at frequencies harmonically related to common clock oscillators. These complex intermodulation products highlight the necessity for detailed follow-up of any signal of interest using a procedure such as the one outlined in this work.
Image processing techniques to estimate weight and morphological parameters for selected wheat refractions
Authors: Sharma Rohit , Kumar Mahesh , Alam M. S. 
Published: October 2021

AbstractThe geometric and color features of agricultural material along with related physical properties are critical to characterize and express its physical quality. The experiments were conducted to classify the physical characteristics like size, shape, color and texture and then workout the relationship between manual observations and using image processing techniques for weight and volume of the four wheat refractions i.e. sound, damaged, shriveled and broken grains of wheat variety PBW 725. A flatbed scanner was used to acquire the images and digital image processing method was used to process the images and output of image analysis was compared with the actual measurements data using digital vernier caliper. A linear relationship was observed between the axial dimensions of refractions between manual measurement and image processing method with R2 in the range of 0.798–0.947. The individual kernel weight and thousand grain weight of the refractions were observed to be in the range of 0.021–0.045 and 12.56–46.32 g respectively. Another linear relationship was found between individual kernel weight and projected area estimated using image processing methodology with R2 in the range of 0.841–0.920. The sphericity of the refractions varied in the range of 0.52–0.71. Analyses of the captured images suggest ellipsoid shape with convex geometry while the same observation was recorded by physical measurements also. A linear relationship was observed between the volume of refractions derived from measured dimensions and calculated from image with R2 in the range of 0.845–0.945. Various color and grey level co-variance matrix texture features were extracted from acquired images using the open-source Python programming language and OpenCV library which can exploit different machine and deep learning algorithms to properly classify these refractions.
Experimental evaluation and surface integrity analysis of cryogenic coolants approaches in the cylindrical plunge grinding
Authors: Abedrabbo Faruk , Soriano Denis , Madariaga Aitor , Fernández Raúl , Abolghasem Sepideh , Arrazola Pedro J. 
Published: October 2021

AbstractReplacement of pollutant fluids with eco-friendly strategies in machining operations significantly contributes to protecting the environment, diminishing global warming, and ensuring a healthier workplace for employees. This study compares cryogenic coolants with conventional coolants in cylindrical plunge grinding using a Cubic Boron Nitride (CBN) wheel. Samples of 27MnCr5 steel used in the manufacture of automotive transmission components were ground using (i) Liquid Nitrogen (LN2), (ii) a combination of LN2 + Minimum Quantity Lubrication (MQL), and (iii) a conventional coolant. The effects of the different cooling methods on the surface integrity of the ground surfaces were examined in terms of surface roughness, microstructural defects, microhardness profiles, and residual stresses. In general, surface roughness was similar for the tested cooling systems, even after grinding three subsequent surfaces in which the process stability was analyzed. Interestingly, the use of eco-friendly cryogenic systems induced fewer microstructural defects than conventional systems, and particularly, LN2+MQL lead to more compressive surface residual stresses that would improve the in-service performance of components. These results show opportunities for replacing conventional pollutant systems with eco-friendly cryogenic strategies for refrigerating/lubricating grinding processes to reduce harmful effects on the environment and pose health risks to operators.
A stochastic model explains the periodicity phenomenon of influenza on network
Authors: Yang Hong , Jin Zhen 
Published: October 2021

AbstractInfluenza is an infectious disease with obvious periodic changes over time. It is of great practical significance to explore the non-environment-related factors that cause this regularity for influenza control and individual protection. In this paper, based on the randomness of population number and the heterogeneity of population contact, we have established a stochastic infectious disease model about influenza based on the degree of the network, and obtained the power spectral density function by using the van Kampen expansion method of the master equation. The relevant parameters are obtained by fitting the influenza data of sentinel hospitals. The results of the numerical analysis show that: (1) for the infected, the infection period of patients who go to the sentinel hospitals is particularly different from the others who do not; (2) for all the infected, there is an obvious nonlinear relationship between their infection period and the visiting rate of the influenza sentinel hospitals, the infection rate and the degree. Among them, only the infection period of patients who do not go to the sentinel hospitals decreased monotonously with the infection rate (increased monotonously with the visiting rate), while the rest had a non-monotonic relationship.
The influence of water hardness perturbations on bubble departure dynamics
Authors: Dzienis P. , Mosdorf R. , Czarnecki J. 
Published: October 2021

AbstractThe influence of small changes to water hardness on the nonlinear behaviour of liquid penetration into a capillary and the resulting air pressure fluctuations during air bubble formation are examined in this paper. Experiments were undertaken in which bubbles were generated both in water having a surface tensile force of σ = 72.2 mN/m and in an aqueous solution of calcium carbonate having a surface tensile force of σ = 75.4 mN/m, each contained in a glass capillary with an internal diameter of 1 mm. It is shown that both the maximum value of liquid penetration into the capillary and bubble growth time are affected by perturbations to the water hardness. The time it takes for the bubble to depart the capillary was estimated using the following nonlinear data analysis methods: time delay (τ), attractor reconstructions, correlation dimension (D), and largest Lyapunov exponent (λ). All estimates demonstrate that the pressure fluctuations in the c–c aqueous solutions and extent of liquid solution penetration into the capillary during the time between subsequent bubble departures behave chaotically. Furthermore, this work demonstrates that the dynamics of bubble formation along with the bubble waiting time are very sensitive to small perturbation in the physical properties of the liquid, and this sensitivity has a significant effect on the observed chaotic behaviour.
Aortic annulus sizing in bicuspid and tricuspid aortic valves using CT in patients with surgical aortic valve replacement
Authors: Choe Jooae , Koo Hyun Jung , Kang Joon-Won , Kim Joon Bum , Kang Hee Jun , Yang Dong Hyun 
Published: October 2021

AbstractThe purpose of this study was to evaluate whether bicuspid anatomy affects the discrepancy between CT-derived annular size and intraoperative size. We retrospectively analyzed annular measurements in 667 patients who underwent surgical aortic valve replacement (AVR). Preoperative CT measurements of the aortic annulus were compared to surgically implanted valve sizes. To evaluate whether the bicuspid valve affects the differences between CT annulus diameter and surgical AVR size, patients with diameter larger by > 10% (CT-Lg group) on CT, compared to surgical AVR size, were compared with those having size difference < 10% (CT-Sim group). Propensity score matching yielded 183 matched patients from each group. Bicuspid aortic valve annulus parameters significantly correlated with surgical aortic valve size (r = 0.52–0.71; for all, p < 0.01). The most representative measurements corresponded to surgical aortic valve size were area-derived diameters in tricuspid aortic valve (r = 0.69, p < 0.001) and bicuspid without raphe (r = 0.71, p < 0.001), and perimeter-derived diameter in bicuspid with raphe (r = 0.63, p < 0.001). After propensity score matching, native valve type was not different between CT-Sim and CT-Lg groups. In multivariable analysis, the difference between CT-derived diameter and surgical AVR size was affected by the operator factor and types of prosthesis. Bicuspid aortic annulus diameters measured on CT showed a significant correlation with surgical aortic valve size. The difference between CT-derived diameter and surgical AVR size is affected by operator factor and the types of prosthesis but not affected by the bicuspid valve.
Molecular search by NMR spectrum based on evaluation of matching between spectrum and molecule
Authors: Kwon Youngchun , Lee Dongseon , Choi Youn-Suk , Kang Seokho 
Published: October 2021

AbstractInferring molecular structures from experimentally measured nuclear magnetic resonance (NMR) spectra is an important task in many chemistry applications. Herein, we present a novel method implementing an automated molecular search by NMR spectrum. Given a query spectrum and a pool of candidate molecules, the matching score of each candidate molecule with respect to the query spectrum is evaluated by introducing a molecule-to-spectrum estimation procedure. The candidate molecule with the highest matching score is selected. This procedure does not require any prior knowledge of the corresponding molecular structure nor laborious manual efforts by chemists. We demonstrate the effectiveness of the proposed method on molecular search using 13C NMR spectra.
Macroalgae in biomonitoring of metal pollution in the Bay of Bengal coastal waters of Cox’s Bazar and surrounding areas
Authors: Rakib Md.Refat Jahan , Jolly Y. N. , Dioses-Salinas Diana Carolina , Pizarro-Ortega Carlos Ivan , De-la-Torre Gabriel Enrique , Khandaker Mayeen Uddin , Alsubaie Abdullah , Almalki Abdulraheem S. A. , Bradley D. A. 
Published: October 2021

AbstractAlthough coastal water marine algae have been popularly used by others as indicators of heavy metal pollution, data within the Bay of Bengal for the estuarine Cox’s Bazar region and Saint Martin’s Island has remained scarce. Using marine algae, the study herein forms an effort in biomonitoring of metal contamination in the aforementioned Bangladesh areas. A total of 10 seaweed species were collected, including edible varieties, analyzed for metal levels through the use of the technique of EDXRF. From greatest to least, measured mean metal concentrations in descending order have been found to be K > Fe > Zr > Br > Sr > Zn > Mn > Rb > Cu > As > Pb > Cr > Co. Potential toxic heavy metals such as Pb, As, and Cr appear at lower concentration values compared to that found for essential mineral elements. However, the presence of Pb inSargassum oligocystumspecies has been observed to exceed the maximum international guidance level. Given that some of the algae species are cultivated for human consumption, the non-carcinogenic and carcinogenic indices were calculated, shown to be slightly lower than the maxima recommended by the international organizations. Overall, the present results are consistent with literature data suggesting that heavy metal macroalgae biomonitoring may be species-specific. To the best of our knowledge, this study represents the first comprehensive macroalgae biomonitoring study of metal contamination from the coastal waters of Cox’s Bazar and beyond.
PIM1 phosphorylation of the androgen receptor and 14-3-3 ζ regulates gene transcription in prostate cancer
Authors: Ruff Sophie E. , Vasilyev Nikita , Nudler Evgeny , Logan Susan K. , Garabedian Michael J. 
Published: October 2021

AbstractPIM1 is a serine/threonine kinase over-expressed in prostate cancer. We have previously shown that PIM1 phosphorylates the androgen receptor (AR), the primary therapeutic target in prostate cancer, at serine 213 (pS213), which alters expression of select AR target genes. Therefore, we sought to investigate the mechanism whereby PIM1 phosphorylation of AR alters its transcriptional activity. We previously identified the AR co-activator, 14-3-3 ζ, as an endogenous PIM1 substrate in LNCaP cells. Here, we show that PIM1 phosphorylation of AR and 14-3-3 ζ coordinates their interaction, and that they extensively occupy the same sites on chromatin in an AR-dependent manner. Their occupancy at a number of genes involved in cell migration and invasion results in a PIM1-dependent increase in the expression of these genes. We also use rapid immunoprecipitation and mass spectrometry of endogenous proteins on chromatin (RIME), to find that select AR co-regulators, such as hnRNPK and TRIM28, interact with both AR and 14-3-3 ζ in PIM1 over-expressing cells. We conclude that PIM1 phosphorylation of AR and 14-3-3 ζ coordinates their interaction, which in turn recruits additional co-regulatory proteins to alter AR transcriptional activity.