bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Interplay Between Fear of Falling, Balance Performance, and Future Falls: Data From the National Health and Aging Trends Study
Authors: Garbin Alexander J. , Fisher Beth E. 
Published: August 2021

Background and Purpose:
Fear of falling is common in older adults and greatly increases their risk for falls. Interventions aimed at reducing fall risk in older adults with a fear of falling typically aim to improve balance. However, this approach has limited success, and the idea that balance performance impacts fall risk in this population is largely based on research in the general older adult population. The aim of this study was to assess whether presence of fear of falling modifies the relationship between balance performance and future falls in a sample of nationally representative older adults.

Methods:
We analyzed data from 5151 community-dwelling Medicare beneficiaries (65 years or older) from waves 1 and 2 of the National Health and Aging Trends Study. In this prospective cohort study, balance performance and fear of falling were recorded during wave 1, while a report of a fall was recorded during wave 2 (1-year follow-up). The interplay between fear of falling, balance performance, and fall risk was analyzed using logistic regression with fear of falling as a moderating variable while controlling for common confounding variables.

Results:
Twenty-seven percent of participants reported a fear of falling at wave 1 while 32.7% reported a fall at wave 2. Reduced balance performance was significantly associated with increased future fall likelihood in individuals with and without a fear of falling (P = .008). Further, the presence of fear of falling did not modify the association between balance and future falls (P = .749). Fear of falling was associated with increased future fall likelihood independent of balance performance (P < .001).

Conclusion:
These findings demonstrate that fear of falling did not modify the relationship between balance performance and future fall risk, thus suggesting that balance training is appropriate to reduce falls in older adults with a fear of falling. However, balance training alone may be insufficient to optimally reduce falls in older adults with a fear of falling, as the presence of this fear increased future fall risk independent of balance performance.
Practical Strategies for Integrating Strength and Conditioning Into Early Specialization Sports
Authors: Moeskops Sylvia , Oliver Jon L. , Read Paul J. , Cronin John B. , Myer Gregory D. , Lloyd Rhodri S. 
Published: August 2021

ABSTRACT
Early sport specialization involves physically immature children participating in intensive year-round training and/or competition for a single sport. The lack of sport exposure and diversification during the developmental years may underlie the increased risk of overuse injuries, blunting of motor skill development, psychosocial issues, overtraining syndrome, burnout, and potential dropout from sport. With increasing number of youth choosing, or being encouraged, to specialize at an early age, we aim to provide evidence-based recommendations for the integration of strength and conditioning into the development programs of young athletes who participate in sports with a culture of early specialization. In addition to the principles of programming, strategies are provided relative to monitoring of growth, maturation, and training load to illustrate the potential complexities of attempting to optimize long-term athletic development in early specializing athletes.
Estrategias de intervención educativa en el área de inglés en educación primaria para estudiantes con trastorno por déficit de atención e hiperactividad
Authors: Moro-Ramos Sandra 
Published: August 2021

Introducción. El siguiente artículo presenta el análisis que se realizó sobre la pedagogía de una maestra de lengua extranjera (inglés) en un colegio de educación primaria. Objetivo. El objetivo de esta actuación es analizar la pedagogía de la especialista en lengua extranjera (inglés); concretamente, examinar las medidas llevadas a cabo con el alumnado con trastorno por déficit de atención e hiperactividad (TDAH). Se pretende plantear un modelo realista en el paradigma de la enseñanza y el aprendizaje de la lengua anglosajona como segunda lengua con escolares con TDAH. Metodología. A través de la técnica de investigación documental, se revisará la práctica educativa, se analizarán y pondrán en práctica diversas metodologías y se modificará la praxis educativa para añadir los ajustes de intervención necesarios para que todo el alumnado, con TDAH o sin este, aprenda inglés como ESL (del inglés English as a Second Language). Resultados. A partir de este análisis, se mostrarán una serie de estrategias para trabajar el área de inglés con escolares con TDAH. Discusión. Partiendo de que este es un trastorno neurobiológico en el que la repercusión que tiene en cada persona es distinta y las áreas en las que pueden presentar problemas difieren de unas a otras, se proponen diversas actividades y tácticas basadas en el análisis del discurso para dotar a estas personas de las destrezas necesarias para la adquisición del inglés como segundo idioma. Asimismo, en el presente artículo se muestran dos modelos para el entrenamiento cognitivo de niños y niñas con hiperactividad o sin esta para actividades orales y escritas en inglés como L2.
Prevalence and antifungal drug resistance of dermatophytes in the clinical samples from Pakistan
Authors: Usman Bakhtawar , Rehman Abdul , Naz Iffat , Anees Muhammad 
Published: August 2021

AbstractDermatophytosis is a major health problem all over the world including Pakistan. This is the first report of detection of dermatophytes and their antifungal drug resistance in the Northern and Western parts of Pakistan. A total of 154 samples were collected from different hospitals of Khyber Pakhtunkhwa, and out of them 136 samples were found positive. Tinea corporis (35%) was the most predominant type of infection followed by Tinea capitis (22%). The fungi identified in Tinea corporis infection types were identified as Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum. The fungi identified in Tinea capitis included Trichophyton violaceum, T. mentagrophytes, Microsporum ferrugineum. The gender wise distribution showed both males (52%) and females (48%) were infected with the fungi. More cases belonged to the rural parts of the country. Age wise distribution showed that the infection was more prevalent in the children and the prevalence decreased with the increase in age. The positive samples were checked against two antifungal agents: fluconazole and nystatin. Among 136 positive samples, none of the isolates showed resistance to nystatin while 7% of the samples showed resistance to fluconazole. The resistant isolates were then identified by amplifying the 18S rRNA gene, using universal primers (ITS1, ITS4). Among the 9 resistant isolates, 5 isolates were identified as Trichophyton spp., 3 as Microsporum spp. and 1 as Epidermophyton spp.
PIPERINE-LOADED CHITOSAN NANOPARTICLES: PREPARATION AND CHARACTERIZATION
Authors: Nhi Tran Thi Y , Trinh Cong Duc , Truong Thien Do , Quang Tuan Le , Pham Hanh Bich , Lai Thuy Thi , Le Ha Thi Thanh 
Published: August 2021

Abstract – HCTN7. Plasma cholesterol level plays an important role in atherosclerosis and cardiovascular diseases. Piperine, an alkaloid form of black pepper is known to reduce cholesterol uptake. In this paper, piperine-loaded chitosan nanoparticles (CTS-PIP NPs) were prepared by ionic gelation method. Molecular interactions among the components were confirmed by FT-IR spectroscopy. Transmission electron microscopy (TEM) images revealed spherical-shaped nanoparticles with diameter of <100 nm. CTS-PIP NPs displayed positive ζ-potential(ZP) of about 31.6 mV. Dynamic light scattering (DLS) particle size (PS) distribution analysis indicated the mean particle size of CTS-PIP NPs was 245.9 nm, polydispersity index of 31%
The Prognostic Significance of Body Mass Index and Metabolic Parameter Variabilities in Predialysis CKD: A Nationwide Observational Cohort Study
Authors: Park Sehoon , Cho Semin , Lee Soojin , Kim Yaerim , Park Sanghyun , Kim Yong Chul , Han Seung Seok , Lee Hajeong , Lee Jung Pyo , Joo Kwon Wook , Lim Chun Soo , Kim Yon Su , Han Kyungdo , Kim Dong Ki 
Published: August 2021

Significance statement
The prognostic significance of variabilities in body mass index (BMI) or metabolic parameters in patients with CKD is uncertain. In this observational cohort study of 84,636 patients with predialysis CKD in South Korea, the authors analyzed the association between variability of BMI or various metabolic parameters and risks of all-cause mortality and incident myocardial infarction, stroke, and requirement for KRT. They found that elevated variability in BMI or certain metabolic parameters was associated with higher risks of adverse outcomes, independent of baseline metabolic status. These findings may encourage clinicians in the nephrology field to carefully assess not only baseline BMI or metabolic status in patients with CKD, but also the fluctuating status of metabolic parameters, due to their potential prognostic significance in such patients.

Background
The association between variabilities in body mass index (BMI) or metabolic parameters and prognosis of patients with CKD has rarely been studied.

Methods
In this retrospective observational study on the basis of South Korea’s national health screening database, we identified individuals who received ≥3 health screenings, including those with persistent predialysis CKD (eGFR <60 ml/min per 1.73 m2 or dipstick albuminuria ≥1). The study exposure was variability in BMI or metabolic parameters until baseline assessment, calculated as the variation independent of the mean and stratified into quartiles (with Q4 the highest quartile and Q1 the lowest). We used Cox regression adjusted for various clinical characteristics to analyze risks of all-cause mortality and incident myocardial infarction, stroke, and KRT.

Results
The study included 84,636 patients with predialysis CKD. Comparing Q4 versus Q1, higher BMI variability was significantly associated with higher risks of all-cause mortality (hazard ratio [HR], 1.66; 95% confidence interval [95% CI], 1.53 to 1.81), P [for trend] <0.001), KRT (HR, 1.20; 95% CI, 1.09 to 1.33; P<0.001), myocardial infarction (HR, 1.19; 95% CI, 1.05 to 1.36, P=0.003), and stroke (HR, 1.19; 95% CI, 1.07 to 1.33, P=0.01). The results were similar in the subgroups divided according to positive or negative trends in BMI during the exposure assessment period. Variabilities in certain metabolic syndrome components (e.g., fasting blood glucose) also were significantly associated with prognosis of patients with predialysis CKD. Those with a higher number of metabolic syndrome components with high variability had a worse prognosis.

Conclusions
Higher variabilities in BMI and certain metabolic syndrome components are significantly associated with a worse prognosis in patients with predialysis CKD.
MEDIA DOMINASI (DOMINO SISTEM KOORDINASI) UNTUK SISWA KELAS XI SMA/MA
Authors: Sodiq Muhammad Yusuf Fajar , Sholihah Mar'atus , Anggraini Dian Puspita 
Published: August 2021

Abstrak. Penelitian ini bertujuan untuk mengembangkan media domino sebagai media pembelajaran Biologi pada materi sistem koordinasi untuk siswa kelas XI SMA/MA. Data penelitian berupa data kelayakan media yang diambil dari hasil validasi ahli media, materi, bahasa, respon guru dan respon siswa. Pengambilan data pada penelitian ini menggunakan instrumen berupa angket validasi ahli media, materi, bahasa, respon guru serta respon siswa. Analisis data dilakukan secara deskriptif. Hasil validasi menunjukkan penilaian ahli materi memperoleh persentase sebesar 75 persen dengan kriteria layak, ahli bahasa sebesar 82,2 persen dengan kriteria sangat layak, ahli media sebesar 78 persen dengan kriteria layak, respon guru biologi 76,4 persen dengan kriteria layak, dan respon siswa sebesar 83,5 persen dengan kriteria sangat layak. Hasil yang diperoleh menunjukkan bahwa media dominasi layak digunakan sebagai media pembelajaran biologi khususnya materi sistem koordinasi untuk kelas XI SMA/MA.Abstract.This study aims to develop domino media as a learning media for biology in the coordination system material for class XI SMA / MA students. The research data is in the form of media feasibility data taken from the validation results of media experts, material, language, teacher responses and student responses. Retrieval of data in this study using instruments in the form of validation questionnaires for media experts, materials, language, teacher responses and student responses. Data analysis was carried out descriptively. The validation results showed that the material expert's assessment obtained a percentage of 75 percent with proper criteria, 82.2 percent of language experts with very feasible criteria, 78 percent of media experts with proper criteria, 76.4 percent of biology teacher responses with proper criteria, and student responses amounted to 83.5 percent with very feasible criteria. The results obtained indicate that the media of dominance is suitable for use as a media for learning biology, especially the material for the coordination system for class XI SMA / MA.
Evaluation of S-100 immunostaining in the demonstration of nerve changes in tuberculoid and borderline tuberculoid leprosy - A descriptive, prospective and retrospective analytical study
Authors: Manjunath Sowmya S , Manjunath G V , Basavaraj Vijaya 
Published: August 2021

S-100 immunohistochemical staining may detect nerve involvement in early stages of tuberculoid spectrum of leprosy. This study investigated the use of S-100 in early diagnosis of the tuberculoid and borderline tuberculoid leprosy and compared its sensitivity with hematoxylin and eosin (HE) stains in discerning the nerve involvement.To study the different histopathological patterns of nerve involvement in tuberculoid and borderline tuberculoid leprosy on S-100 immunostaining and also to compare the sensitivity of HE stain with S-100 immunostain in discerning the nerve involvement in these cases.This was a descriptive, prospective and retrospective analytical study, which included patients with tuberculoid spectrum of leprosy. Histopathological examination (HPE) and immunohistochemical (IHC) analysis were performed on all skin biopsies using HE stain and S-100 immunostain, respectively. Then the sensitivities of both the stains in discerning the nerve involvement were calculated and the data was analyzed using SPSS software version 22 by applying chi-square test.The study included a total of 58 patients [tuberculoid (n=28), borderline tuberculoid (n=30)]. The mean age was 43 yrs. The most common clinical manifestation was hypopigmented patches (n=40, 70%) with loss of sensation (n=39, 68.3%). HPE revealed 36 cases with well-defined granulomas, 22 cases with ill-defined granulomas and 41 cases with nerve destruction. IHC analysis showed four different patterns of nerve damage (fragmented, n=32; infiltrated and fragmented, n=14; infiltrated, n=10; intact, infiltrated and fragmented; n=1). The sensitivity and positive predictive value (PPV) of HE staining in delineating the nerve involvement were 68.96% and 100%, respectively. Whereas, the sensitivity and PPV of S-100 IHC were 100% each.Less number of cases.Use of S-100 IHC along with HPE aids in early, accurate and confirmatory diagnosis.
Hydatid cyst of spleen: A rare presentation
Authors: Thapa Garima , Aruna  , Shah Bikram 
Published: August 2021

: Hydatid cyst is a parasitic infestation caused by Echinococcus granulosus. The spleen being rarely involved by the parasite, commonly involved organs are liver followed by lungs. It constitutes only 4% of abdominal hydatid diseases. Its worldwide incidence is 0.5 to 4%. In this case report, we present a case of young boy with concomitant splenic and liver hydatid cysts. A 8-year-old boy, resident of Chamba district was presented with abdominal pain, fever and left upper quadrant swelling. The swelling had started enlarging over past 4 months. After necessary investigations it was diagnosed as hydatid cyst of spleen concomitant with liver and was confirmed by histopathological examination of the cyst membrane. All routine investigations other than anemia of 9.4 mg/dl and raised Ecchinococcus IGG serum levels, all other tests were within normal range. Splenic hydatid is a rare entity and among abdominal presentations of hydatid diseases its incidence is very low, being 4% only. Diagnosis can be made on CECT abdomen along with the Echinococcus IGG serum levels, cytology of aspirated cystic fluid and then can be confirmed on histopathological examination of the cyst membrane sent for the histopathological examination. This case report emphasizes the need of considering hydatid cyst as a differential with uncommon presentation of the disease even in non- endemic area, as in this case patient presented with splenomegaly and abdominal pain.
Granular cell tumour of cecum mimicking a neuroendocrine tumor
Authors: Pol Jaydeep N , Kadkol Girish A , Phadke Madhura D , Magdum Swpana S 
Published: August 2021

Granular cell tumor (GCT) is a benign soft tissue neoplasm generally believed to be of nerve sheath origin. It is most frequently seen in skin, subcutaneous tissue and oral cavity. GCTs are uncommon in gastrointestinal tract (GIT), in which the majority are located in the esophagus. In this article, we report a case of GCT involving cecum in a 22 years lady. She had a sessile polyp in the cecum which was thought to be NET. Typical histomorphology and expression of S-100 on immunohistochemistry confirmed the diagnosis.We have reviewed, the GCTs of cecum reported previously with emphasis on the differential diagnosis. To best of our knowledge, this is only the 3 case of GCT of cecum reported in the Indian literature. Colonic GCTs are extremely uncommon. This is just the third case of GCT of colon in Indian literature. GCTs pose a diagnostic challenge due to lack of symptoms or nonspecific symptoms. Awareness of this entity helps in preventing misdiagnosis as happened in this case and avoiding further unnecessary treatment.
Rusycystyka w Izraelu. Od kulturowej separacji do demarginalizacji kultury rosyjsko-żydowskiej
Authors: Lenart Agnieszka 
Published: August 2021

Celem badań jest omówienie kondycji izraelskiej rusycystyki. W tekście wskazuje się uwarunkowania społeczno-polityczne, które wpłynęły na wzrost rangi języka rosyjskiego, omawia się dynamikę spadku jego atrakcyjności, a także perspektywy zainteresowania kulturą rosyjską w Izraelu. Autorka artykułu wymienia nazwiska izraelskich rusycystów i slawistów, omawia ich preferencje badawcze i osiągnięcia w zakresie światowych badań slawistycznych. Badania izraelskich rusycystów dotyczą przede wszystkim literatury pierwszej fali emigracji rosyjskiej. W ostatnim czasie coraz częściej podejmowane są prace nad literaturą rosyjską w kontekście żydowskim i izraelskim. Z przeprowadzonej analizy wynika, że rusycystyka w Izraelu najbardziej intensywnie rozwijała się w latach 90. W XXI wieku zainteresowanie rusycystyką w Izraelu spada ze względu na słabszą znajomość języka i kultury rosyjskiej wśród młodszego pokolenia repatriantów. Wpływ na ten stan rzeczy mają także tendencje światowe i procesy globalizacyjne.
Konceptualizacja śmiechu w językowym obrazie świata Nadieżdy Teffi (na materiale prozy wspomnieniowej)
Authors: Ndiaye Iwona Anna 
Published: August 2021

W centrum uwagi badawczej Autorki pozostaje koncept смех w rosyjskiej literaturze emigracyjnej. Celem artykułu jest analiza danego konceptu w prozie wspomnieniowej Nadieżdy Teffi, pisarki pierwszej fali emigracji rosyjskiej. Przedmiot niniejszej analizy stanowi leksyka wyekscerpowana z tomów Wspomnienia (1933) oraz Moja kronika (2015). Analiza została ukierunkowana na wyodrębnienie semantycznej struktury konceptu oraz sposobów jego lingwistycznego wyrażenia w tekście literackim.
W procesie analizy odwołaliśmy się do metodologii zaproponowanej przez Josifa Sternina, co pozwoliło wyróżnić w strukturze konceptów różnorodne jednostki mentalne autorskiego obrazu świata, werbalizowane w tekstach literackich (sensy i wyobrażenia obiektywne oraz indywidualno-autorskie).
Ponadto w badaniu wykorzystano metodę opisową oraz analizę funkcjonalno-stylistyczną.
Na podstawie przeprowadzonej analizy lingwistycznej możemy wnioskować, że koncept смех jest szeroko reprezentowany w prozie wspomnieniowej Teffi. Indywidualno-autorskie znaczenia reprezentujące peryferie analizowanego konceptu mają różną konotację. Uczucia i emocje wyrażane za pomocą śmiechu w świecie przedstawionym są zarówno pozytywne, negatywne, jak i neutralne. Częstotliwości użycia jednostek leksykalnych oraz różnorodność ich aktualizacji świadczą o tym, że koncept СМЕХ zajmuje ważne miejsce w językowym obrazie świata Teffi.
Исследования Pоссии/СССР и стран Восточной Европы после холодной войны: новое лицо дисциплины
Authors: Bolshakova Olga 
Published: August 2021

The paper deals with the new developments in the field of Russian and East European studies (REES) after the end of the Cold war, with the focus on the U.S. and Great Britain. Along with organizational and structural changes in the field special attention is devoted to new subjects and trends in the study of the region, with Belarus as a case study. Research in this field began in the 90s and has been booming since the 2000s. Researchers are primarily interested in the history of the country, political science, anthropology, and literary studies. The formation of an international community of researchers allows us to conclude that previously “Western” discipline of REES is gaining a global character.
Сэр Бернард Пэрс и Школа славянских исследований в Лондоне
Authors: Nekrasov Andrei 
Published: August 2021

This article covers the diverse activities of the renowned British historian Sir Bernard Pares on the development of Russian and Slavic studies in the first half of the 20th century. He was the author of several books and a fair number of articles on Russia, edited the journals The Russian Review and The Slavonic Review. Pares also founded the first School of Russian Studies at the University of Liverpool (1907) and served for twenty years as Director of the School of Slavonic and East European Studies at the University of London (1919-1939). Due to his interest in Russian politics, history and culture, frequent and lengthy visits to Russia from 1906 to 1919 and close friendship with many Russian liberals, his appointment as an official observer to the Russian army in 1915 and as a British representative to Kolchak’s army during the Civil War, Pares became one of the most authoritative British experts on Russia and rightfully assumed the position of Director of the School of Slavonic Studies. This article pays close attention to various financial and administrative problems that Pares had to cope with as the Director of the School. The author concludes that Bernard Pares’ role as a promoter of all things Russian, a translator of Russian poetry and prose, a researcher into Russian history and an organiser of Russian and Slavonic studies in Britain was indispensable.