bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cognitive and mental health changes and their vulnerability factors related to COVID-19 lockdown in Italy
Authors: Fiorenzato Eleonora , Zabberoni Silvia , Costa Alberto , Cona Giorgia 
Published: January 2021

The COVID-19 pandemic and government imposed social restrictions like lockdown exposed most individuals to an unprecedented stress, increasing mental health disorders worldwide.
We explored subjective cognitive functioning and mental health changes and their possible interplay related to COVID-19-lockdown. We also investigated potential risk factors to identify more vulnerable groups. Across Italy, 1215 respondents completed our Qualtrics-based online-survey during the end of a seven to 10-week imposed lockdown and home confinement (from April 29 to May 17, 2020). We found subjective cognitive functioning and mental health severely changed in association with the lockdown. Under government regulations, cognitive complaints were mostly perceived in routine tasks involving attention, temporal orientation and executive functions—with no changes in language abilities. A paradoxical effect was observed for memory, with reduced forgetfulness compared to pre-lockdown. We found higher severity and prevalence of depression, anxiety disorders, abnormal sleep, appetite changes, reduced libido and health anxiety: with mild-to-severe depression and anxiety prevalence climbing to 32 and 36 percent, respectively, under restrictions. Being female, under 45 years, working from home or being underemployed were all identified as relevant risk factors for worsening cognition and mental health. Frequent consumers of COVID-19 mass media information or residents in highly infected communities reported higher depression and anxiety symptoms, particularly hypochondria in the latter. If similar restrictions are reimposed, governments must carefully consider these more vulnerable groups in their decisions, whilst developing effective global and long-term responses to the cognitive and mental health challenges of this type of pandemic; as well as implementing appropriate psychological interventions with specific guidelines: particularly regarding exposure to COVID-19 mass-media reports.
Understanding the Contribution of Insulin Resistance to the Risk of Pancreatic Cancer
Authors: Toledo Frederico G.S. , Chari Suresh , Yadav Dhiraj 
Published: January 2021

Abstract
Type 2 diabetes is a known risk factor for the development of pancreatic adenocarcinoma. However, the mechanisms behind this epidemiological association remain unclear. Whether it is hyperglycemia or insulin resistance that increases the risk of pancreatic adenocarcinoma is a question that has yet to be settled. A new study by Kim et al published in The American Journal of Gastroenterology shows that the presence of insulin resistance independently increases pancreatic cancer mortality even in individuals without diabetes and hyperglycemia. The study's findings and implications to our understanding of pancreatic cancer risk are discussed.
Profitability of Sugar Beet Crop in 2018/2019 Campaign on the Example of Lubelskie Province
Authors: Krzysiak Zbigniew 
Published: January 2021

AbstractThe work presents a complex analysis and cost accounting of beet sugar cultivation in 2018/2019 campaign for individual farms of Lublin region. The economic results obtained by producers are mainly affected by indirect costs accounting for 60.11% of the revenue from the total production. Within this group of costs, the major components are sowing service, harvest and soil liming operations reaching 39.38%. Sugar beet production in the analyzed campaign was profitable, with the profitability index of 1.24 and unit production cost 14.33 PLN∙dt−1is considered one of the profit-making activities in agricultural production, yet it is characterized by a high production cost that gobbled up to 80.39% of the total revenue in the analyzed 2018/19 campaign. The main factor influencing the income from sugar beet cultivation was the price for the raw material, which in the considered business year in relation to the previous season increased by only 0.77 PLN∙t−1.
EVOSHEEP: the makeup of sheep breeds in the ancient Near East
Authors: Vila Emmanuelle , Abrahami Philippe , Albesso Moussab , Amane Agraw , Bader Camille , Berthon Rémi , Bouzid Sofiane , Bradley Daniel , Breniquet Catherine , Chahoud Jwana , Cucchi Thomas , Davoudi Hossein , de Cupere Bea , Escarguel Gilles , Estrada Oscar , Gourichon Lionel , Helmer Daniel , Huangfu Wei , Lesur Joséphine , Mashkour Marjan , Michel Cécile , Mohaseb Azadeh , Orlando Ludovic , Pompanon François , Studer Jacqueline , Vuillien Manon 
Published: January 2021

Abstract
Las construcciones rurales en la formación laboral de los estudiantes desde la Disciplina Principal Integradora
Authors: Zaragoza Morales Nurbia Ivia , Cruz Cabezas Miguel Alejandro , Martínez  Cuba Orlando 
Published: January 2021

Contexto: La inserción laboral de los estudiantes de Licenciatura en Educación Construcción en construcciones rurales desde el proceso de enseñanza aprendizaje profesional de la Disciplina Principal Integradora, favorece su formación laboral. Desde este contexto laboral los estudiantes se vinculan a las tipologías constructivas que identifican su identidad cultural, la historia, su relación directa con los agentes de la naturaleza, el uso de materiales locales que les permita desempeñarse con una visión próspera y sustentable para la conservación y protección del ecosistema durante la ejecución de construcciones rurales.
Objetivo: Fundamentar la incidencia de las construcciones rurales como contexto laboral del proceso de enseñanza aprendizaje profesional de la Disciplina Principal Integradora para la formación laboral de los estudiantes de Licenciatura en Educación Construcción.
Métodos: Los métodos esenciales que se emplearon son el análisis-síntesis, la inducción-deducción y la observación científica, los que permitieron evidenciar las insuficiencias en la formación laboral de los estudiantes de Licenciatura en Educación Construcción desde la Disciplina Principal Integradora para su desempeño en construcciones rurales.
Resultados: Se ofrecen las cualidades laborales y los rasgos de manifestación que caracterizan al Licenciado en Educación Construcción para su desempeño en las construcciones rurales como contexto laboral de la Disciplina Principal Integradora con una visión próspera y sustentable.
Ajuste escolar e ideación suicida en adolescentes escolarizados en una institución educativa de Puerto Colombia
Authors: Expósito-Concepción Maria Yaquelin , Guevara-Novoa Claudia , Niño-Ruiz Elias David , Marthe-Manjarrés Alexandra , Visbal-Mackenzie Aleida , Borré-Ortíz Yeis Miguel 
Published: January 2021

El suicidio y sus intentos configuran uno de los problemas relevantes de la salud pública actual.Objetivo: describir la relación entre ajuste escolar e ideación suicida en adolescentes escolarizados. Se identificaron los principales factores de riesgo y factores protectores en la ideación suicida, y se determinó la relación entre variables.Metodología: estudio descriptivo correlacional, a través de muestreo probabilístico estratificado se seleccionaron 413 estudiantes de 6° a 11° grado. Los instrumentos evaluaron ideación suicida y ajuste escolar. Se utilizaron técnicas de inferencia bayesiana y aprendizaje de máquina con el objetivo de modelar el comportamiento de los diferentes instrumentos. Se utilizó Octave como herramienta computacional de apoyo.Resultados: se encontró una correlación negativa de ajuste escolar e ideación suicida. Los adolescentes pueden desarrollar una ideación suicida como consecuencia de los siguientes factores: bajo rendimiento escolar, 52 %; bajas expectativas académicas, 27 %; problemas de integración escolar, 68 %.Conclusiones: adolescentes con altos niveles de ideación suicida pueden estar relacionados con bajos niveles de ajuste escolar. El adolescente con incapacidad de establecer lazos de amistad entre compañeros, que se siente aislado y tiene mal desempeño escolar podrá buscar salidas o escapes negativos como pueden ser la ideación suicida.
Barreiras Identificadas em Contratações Públicas Sustentáveis: uma análise de uma organização pública ## Barriers Identified in Sustainable Procurement: analysis of a public organization
Authors: Torres Filho Dalmir Machado Torres Filho , Corrêa Marcos Paulo De Oliveira , Rodrigues Mariana Da Silva , Fahel Murilo Cássio Xavier 
Published: January 2021

ResumoA possível crise ambiental levanta questionamentos quanto ao impacto que as escolhas de consumo têm no agravamento do problema ou no apontamento de soluções. Essa questão assume maior relevância quando analisada pelo ponto de vista governamental, um dos grandes consumidores de bens e serviços. No intuito de contribuir com as políticas que visam à utilização do poder de compra do Estado para indução de maior sustentabilidade do mercado, este artigo objetiva identificar as principais barreiras postas à maior utilização das Contratações Públicas Sustentáveis (CPS), no caso do Banco Central do Brasil. Como modelo analítico, utilizou-se revisão bibliográfica e documental quanto à evolução das CPS como alicerce de uma metodologia mista, ou seja, quali-quantitativa, com coleta de dados por meio de entrevistas semiestruturadas e questionários. Os fatores estudados foram priorizados levando em conta o grau em que foram considerados enquanto barreiras e o nível de consenso dessas percepções. Dessa forma, foi possível identificar que os preços mais elevados, a dificuldade de identificar os produtos e serviços mais sustentáveis, a incerteza de alguns demandantes em relação à qualidade desses produtos e a falta de treinamento específico constituem as principais barreiras enfrentadas. Por outro lado, a instituição oferece espaço para realização dessas contratações, os servidores atribuem importância a elas e compreendem o porquê de sua utilização.Abstract The current environmental crisis raises questions: consumer choices are part of the aggravation of the problem or can pointing solutions. This issue is more relevant when analyzed from the government point of view, one of the biggest consumers of goods and services. In order to contribute to policies aimed at using the state’s purchasing power to induce greater market sustainability, this paper aims to identify the main barriers to the increased use of Sustainable Public Procurement (SPC) in the case of the Central Bank of Brazil. As an analytical model, a bibliographical and documentary review of the evolution of SPC was used as a basis for a mixed methodology, that is, qualitative and quantitative, with data collection through semi-structured interviews and questionnaires. The factors studied were prioritized considering the degree to which they were considered barriers and the level of consensus of these perceptions. In this way, it was possible to identify that the higher prices, the difficulty of identifying the most sustainable products and services, the uncertainty of some servants regarding the quality of these products and the lack of specific training are the main barriers faced. On the other hand, the institution offers space for accomplishment of these hirings, the servers attach importance, and they understand the reason for their use.
The presence of elk (Alces alces) in Austria since the upper Pleistocene
Authors: Neuner Wolfgang , Spötl Christoph 
Published: January 2021

Abstract
This study reports new data on the occurrence of elk remains in the western, mountainous part of Austria and also provides a compilation of all currently known 107 elk finds of the upper Pleistocene to upper Holocene in this country. The altitudinal distribution reveals two maxima for Austria: a lower one at about 400 m a.s.l., which comprises the alpine foreland, and a second one at about 1600-1800 m a.s.l., reflecting the abundance of vertical caves in the Northern Calcareous Alps at this elevation (animal traps). Vorderkarhöhle in Tyrol is the highest known elk find in Austria (1860 m a.s.l.), interestingly located above the tree line. Although only 11% of all elk sites in Austria have been radiocarbon-dated, stratigraphic and archaeo-logical constraints allow to assign 90% of those sites that lack radiometric dating to either the upper Pleistocene (18%) or the Holocene (72%). Among the latter, upper Holocene sites dominate (78%), followed by middle (16%) and lower Holocene (6%) sites. The youngest radiocarbon-dated elk find in Austria is from Gaflein Valley (Tyrol, 1285-1359 cal BP), in agreement with data from the Swiss Alps, showing that the elk survived beyond Roman times in the Alps and became extinct before the onset of the Middle Ages.
Nevada Seismological Laboratory Rapid Seismic Monitoring Deployment and Data Availability for the 2020 Mww 6.5 Monte Cristo Range, Nevada, Earthquake Sequence
Authors: Bormann Jayne M. , Morton Emily A. , Smith Kenneth D. , Kent Graham M. , Honjas William S. , Plank Gabriel L. , Williams Mark C. 
Published: January 2021

Abstract
The Nevada Seismological Laboratory (NSL) at the University of Nevada, Reno, installed eight temporary seismic stations following the 15 May 2020 Mww 6.5 Monte Cristo Range earthquake. The mainshock and resulting aftershock sequence occurred in an unpopulated and sparsely instrumented region of the Mina deflection in the central Walker Lane, approximately 55 km west of Tonopah, Nevada. The temporary stations supplement NSL’s permanent seismic network, providing azimuthal coverage and near-field recording of the aftershock sequence beginning 1–3 days after the mainshock. We expect the deployment to remain in the field until May 2021. NSL initially attempted to acquire the Monte Cristo Range deployment data in real time via cellular telemetry; however, unreliable cellular coverage forced NSL to convert to microwave telemetry within the first week of the sequence to achieve continuous real-time acquisition. Through 31 August 2020, the temporary deployment has captured near-field records of three aftershocks ML≥5 and 25 ML 4–4.9 events. Here, we present details regarding the Monte Cristo Range deployment, instrumentation, and waveform availability. We combine this information with waveform availability and data access details from NSL’s permanent seismic network and partner regional seismic networks to create a comprehensive summary of Monte Cristo Range sequence data. NSL’s Monte Cristo Range temporary and permanent station waveform data are available in near-real time via the Incorporated Research Institutions for Seismology Data Management Center. Derived earthquake products, including NSL’s earthquake catalog and phase picks, are available via the Advanced National Seismic System Comprehensive Earthquake Catalog. The temporary deployment improved catalog completeness and location quality for the Monte Cristo Range sequence. We expect these data to be useful for continued study of the Monte Cristo Range sequence and constraining crustal and seismogenic properties of the Mina deflection and central Walker Lane.
LIFE, EARTH AND ORE: the life stories of the residents of Piquiá de Baixo in Açailândia-MA network
Authors: Figueiredo César Alessandro Sagrillo , Ramos Carmem Barroso , Rodrigues Jose Siney Ferraz , Pinheiro Roseane Arcanjo , Figueiredo Jean Pierr de Sousa Viana 
Published: January 2021

A comunidade de Piquiá de Baixo, localizada na Cidade de Açailândia/MA, se mantém em luta pelo seu espaço, a fim de manter seu legado e o direito à moradia. Este percurso veio de um longo processo que configurou intenso painel de enfrentamentos, iniciado com a luta pela fixação na terra, com a chegada dos latifundiários e se estendendo até o impacto ambiental causado pelas empresas mineradoras. Nesse cenário conflitivo, trazemos como objetivo examinar as formas de denúncia e resistências dos moradores, tendo como lócus privilegiado de análise as histórias de vida dos moradores. Tratar-se-á de uma pesquisa qualitativa, com dupla abordagem: a cartografia social, que valoriza as memórias coletivas e o discurso em uma rede social que repercute as histórias de vida. Constatamos que há um empoderamento e denúncia política através do ativismo digital, contrário ao discurso hegemônico. A comunidade de Piquiá de Baixo, localizada na Cidade de Açailândia/MA, se mantém em luta pelo seu espaço, a fim de manter seu legado e o direito à moradia. Este percurso veio de um longo processo que configurou intenso painel de enfrentamentos, iniciado com a luta pela fixação na terra, com a chegada dos latifundiários e se estendendo até o impacto ambiental causado pelas empresas mineradoras. Nesse cenário conflitivo, trazemos como objetivo examinar as formas de denúncia e resistências dos moradores, tendo como lócus privilegiado de análise as histórias de vida dos moradores. Tratar-se-á de uma pesquisa qualitativa, com dupla abordagem: a cartografia social, que valoriza as memórias coletivas e o discurso em uma rede social que repercute as histórias de vida. Constatamos que há um empoderamento e denúncia política através do ativismo digital, contrário ao discurso hegemônico.
Ethnographic Study of Tuberculosis Treatment Seeker Behavior on the Island of Buru, Maluku, Indonesia
Authors: Pradani Firda Yanuar , Nurindra Rohmansyah Wahyu , Usman Usman 
Published: January 2021

Background: Tuberculosis (TB) is reported as a world health problem, especially in developing countries. It is estimated that one third of the world's population has been infected by Mycobacterium tuberculosis. WHO has stated that tuberculosis has now become a global threat. Indonesia is one of the 27 countries in the world with MDR-TB cases.
Methods: A qualitative study with an ethnography design was conducted to determine and reveal the meaning of treatment-seeking behavior in “Batu Balender” or TB patients in Buru Island, Maluku, Indonesia. The research data was collected through interviews with 15 informants from all risk groups that are directly related to TB. Observations were made to ensure the validity of the data.
Results: This study revealed that from generation to generation, the Alifuru tribe believes that diseases are grouped into three categories: natural diseases, sick submissions, and ancestral curse. Indigenous people have believed that TB is an incurable ancestral curse disease. They know the "Kaygosa" who is believed to be the holder of natural medicinal plants to treat TB, such as leaves and bark.
Conclusions: Alifuru tribal people who access health services to obtain Directly Observed Treatment Short-Course (DOTS) have experienced failure in treatment due to local customary rules that prohibit taking medicine if a tribal community has died and believes that a community health center or hospital is "house died". This study suggest that education and counseling for TB treatment should be optimized in efforts to improve the health of local tribal communities.
Measurement of gene amplifications related to drug resistance in Plasmodium falciparum using droplet digital PCR
Authors: Srisut Suttipat , Suwannasin Kanokon , Sugaram Rungirun , Dondorp Arjen M. , Imwong Mallika 
Published: January 2021

Abstract
Background: Copy number variations (CNVs) of the Plasmodium falciparum multidrug resistance 1 (pfmdr1), P. falciparum pfplasmepsin2 (pfplasmepsin2) and P. falciparum GTP cyclohydrolase 1 (pfgch1) genes are associated with antimalarial drug resistance in P. falciparum malaria. Droplet digital PCR (ddPCR) assays have been developed for accurate assessment of CNVs in several human genes. The aim of the present study was to develop and validate ddPCR assays for detection of the CNVs of P. falciparum genes associated with resistance to antimalarial drugs.Methods: A multiplex ddPCR assay was developed to detect the CNVs in the pfmdr1 and pfplasmepsin2 genes, while a duplex ddPCR assay was developed to detect CNV in the pfgch1 gene. The gene copy number (GCN) quantification limit, as well as the accuracy and precision of the ddPCR assays were determined and compared to conventional quantitative PCR (qPCR). In order to reduce the cost of testing, a multiplex ddPCR assay of two target genes, pfmdr1 and pfplasmepsin2, was validated. In addition, the CNVs of genes of field samples collected from Thailand from 2015 to 2019 (n = 84) were assessed by ddPCR and results were compared to qPCR as the reference assay.Results: There were no significant differences between the GCN results obtained from uniplex andmultiplex ddPCR assays for detection of CNVs in the pfmdr1 and pfplasmepsin2 genes (p = 0.363 and 0.330, respectively). Based on the obtained gene copy number quantification limit, the accuracy and percent relative standard deviation (%RSD) value of the multiplex ddPCR assay were 95% and 5%, respectively, for detection of the CNV of the pfmdr1 gene, and 91% and 5% for detection of the CNV of the pfplasmepsin2 gene. There was no significant difference in gene copy numbers assessed by uniplex or duplex ddPCR assays regarding CNV in the pfgch1 gene (p = 0.276). The accuracy and %RSD value of the duplex ddPCR assay were 95% and 4, respectively, regarding pfgch1 GCN. In the P. falciparum field samples, pfmdr1 and pfplasmepsin2 GCNs were amplified in 15% and 27% of samples from Ubon Ratchathani, Thailand, while pfgch1 GCN was amplified in 50% of samples from Yala, Thailand. There was 100% agreement between the GCN results obtained from the ddPCR and qPCR assays (κ = 1.00). The results suggested that multiplex ddPCR assay is the optional assay for the accurate detection of gene copy number without requiring calibration standards, while the cost and required time are reduced. Based on the results of this study, criteria for GCN detection by ddPCR analysis were generated.Conclusions: The developed ddPCR assays are simple, accurate, precise and cost-effective tools for detection of the CNVs in the pfmdr1, pfplasmepsin2 and pfgch1 genes of P. falciparum. The ddPCR assay is a useful additional tool for the surveillance of antimalarial drug resistance.
Variation of heart and lung radiation doses according to setup uncertainty in left breast cancer
Authors: Park Sunmin , Rim Chai Hong , Yoon Won Sup 
Published: January 2021

Abstract
Purpose: Breast radiotherapy set-up is often uncertain. Actual dose distribution to normal tissues could be different from planned dose distribution. The objective of this study was to investigate such difference in dose distribution according to the extent of set-up error in breast radiotherapy.Materials and methods: A total of 50 Gy with fraction size of 2 Gy was given to 30 left breasts with different set-ups applying a deep inspiration breath holding (DIBH) or a free breathing (FB) technique. Under the assumption that errors might come from translational axes of deep or caudal directions, the isocenter was shifted from the original tangential alignment every 2.5 mm to simulate uncertainty of deep and caudal tangential set-up in DIBH and FB. Changes were evaluated for dosimetric parameters for the heart, the left ventricle (LV), the left anterior descending coronary artery (LAD), and the ipsilateral lung.Results: On the original plan, mean doses of heart and ipsilateral lung were 2.0 ± 1.1 Gy and 3.7 ± 1.4 Gy in DIBH and 8.4±1.3 Gy and 7.8±1.5 Gy in FB, respectively. The change of dose distribution for the heart in DIBH was milder than that in FB. The deeper the tangential set-up, the worse the heart, LV, LAD, and ipsilateral lung doses, showing as much as 49.4%, 56.4%, 90.3%, and 26.1% shifts, respectively, in 5 mm DIBH setup. The caudal set-up did not show significant dose difference. In multiple comparison of DIBH, differences of mean dose occurred in all 7.5 mm deep set-ups for the heart (p = 0.025), the LV (p = 0.049), and LAD (p = 0.025) in DIBH.Conclusions: To correct set-up error over indicated limitation for deep tangential set-up in DIBH at 5 mm action level, mean heart and ipsilateral lung doses are expected to increase approximately 50% and 25%, respectively.