bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exact four point function for large q SYK from Regge theory
Authors: Choi Changha , Mezei Márk , Sárosi Gábor 
Published: May 2021

AbstractMotivated by the goal of understanding quantum systems away from maximal chaos, in this note we derive a simple closed form expression for the fermion four point function of the largeqSYK model valid at arbitrary temperatures and to leading order in 1/N. The result captures both the large temperature, weakly coupled regime, and the low temperature, nearly conformal, maximally chaotic regime of the model. The derivation proceeds by the Sommerfeld-Watson resummation of an infinite series that recasts the four point function as a sum of three Regge poles. The location of these poles determines the Lyapunov exponent that interpolates between zero and the maximal value as the temperature is decreased. Our results are in complete agreement with the ones by Streicher [1] obtained using a different method.
Radiative muon mass models and (g − 2)μ
Authors: Baker Michael J. , Cox Peter , Volkas Raymond R. 
Published: May 2021

Abstract
Recent measurements of the Higgs-muon coupling are directly probing muon mass generation for the first time. We classify minimal models with a one-loop radiative mass mechanism and show that benchmark models are consistent with current experimental results. We find that these models are best probed by measurements of (g − 2)μ, even when taking into account the precision of Higgs measurements expected at future colliders. The current (g − 2)μ anomaly, if confirmed, could therefore be a first hint that the muon mass has a radiative origin.
New physics effects in leptonic and semileptonic decays
Authors: Bečirević Damir , Jaffredo Florentin , Peñuelas Ana , Sumensari Olcyr 
Published: May 2021

AbstractWe discuss the possibilities of extracting the constraints on New Physics by using the current data on the leptonic and semileptonic decays of pseudoscalar mesons. In doing so we use a general low energy Lagrangian that besides the vector and axial operators also includes the (pseudo-)scalar and tensor ones. In obtaining constraints on New Physics couplings, we combine the experimental information concerning several decay modes with the accurate and precise lattice QCD results for the hadronic matrix elements. We propose to study new observables that can be extracted from the angular analysis of the semileptonic decays and discuss their values both in the Standard Model and in some specific scenarios of physics beyond the Standard Model.
Birational geometry of moduli spaces of perverse coherent sheaves on blow-ups
Authors: Koseki Naoki 
Published: May 2021

AbstractIn order to study the wall-crossing formula of Donaldson type invariants on the blown-up plane, Nakajima–Yoshioka constructed a sequence of blow-up/blow-down diagrams connecting the moduli space of torsion free framed sheaves on projective plane, and that on its blow-up. In this paper, we prove that Nakajima–Yoshioka’s diagram realizes the minimal model program. Furthermore, we obtain a fully-faithful embedding between the derived categories of these moduli spaces.
Heterogeneity of SARS-CoV-2 virus produced in cell culture revealed by shotgun proteomics and supported by genome sequencing
Authors: Gallais Fabrice , Pible Olivier , Gaillard Jean-Charles , Debroas Stéphanie , Batina Hélène , Ruat Sylvie , Sandron Florian , Delafoy Damien , Gerber Zuzana , Olaso Robert , Gas Fabienne , Bellanger Laurent , Deleuze Jean-François , Grenga Lucia , Armengaud Jean 
Published: May 2021

AbstractCOVID-19 is the most disturbing pandemic of the past hundred years. Its causative agent, the SARS-CoV-2 virus, has been the subject of an unprecedented investigation to characterize its molecular structure and intimate functioning. While markers for its detection have been proposed and several diagnostic methodologies developed, its propensity to evolve and evade diagnostic tools and the immune response is of great concern. The recent spread of new variants with increased infectivity requires even more attention. Here, we document how shotgun proteomics can be useful for rapidly monitoring the evolution of the SARS-CoV-2 virus. We evaluated the heterogeneity of purified SARS-CoV-2 virus obtained after culturing in the Vero E6 cell line. We found that cell culture induces significant changes that are translated at the protein level, such changes being detectable by tandem mass spectrometry. Production of viral particles requires careful quality control which can be easily performed by shotgun proteomics. Although considered relatively stable so far, the SARS-CoV-2 genome turns out to be prone to frequent variations. Therefore, the sequencing of SARS-CoV-2 variants from patients reporting only the consensus genome after its amplification would deserve more attention and could benefit from more in-depth analysis of low level but crystal-clear signals, as well as complementary and rapid analysis by shotgun proteomics.
Graphical abstract
Fast, inexpensive, and reliable HPLC method to determine monomer fractions in poly(3-hydroxybutyrate-co-3-hydroxyvalerate)
Authors: Duvigneau Stefanie , Kettner Alexander , Carius Lisa , Griehl Carola , Findeisen Rolf , Kienle Achim 
Published: May 2021

AbstractThe determination of the monomer fractions in polyhydroxyalkanoates is of great importance for research on microbial-produced plastic material. The development of new process designs, the validation of mathematical models, and intelligent control strategies for production depend enormously on the correctness of the analyzed monomer fractions. Most of the available detection methods focus on the determination of the monomer fractions of the homopolymer poly(3-hydroxybutyrate). Only a few can analyze the monomer content in copolymers such as poly(3-hydroxybutyrate-co-3-hydroxyvalerate), which usually require expensive measuring devices, a high preparation time or the use of environmentally harmful halogenated solvents such as chloroform or dichloromethane. This work presents a fast, simple, and inexpensive method for the analysis of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) with high-performance liquid chromatography. Samples from a bioreactor experiment for the production of poly(3-hydroxybutyrate-co-3-hydroxyvalerate) with Cupriavidus necator H16 were examined regarding their monomer content using the new method and gas chromatography analysis, one of the most frequently used methods in literature. The results from our new method were validated using gas chromatography measurements and show excellent agreement.Key points∙ The presented HPLC method is an inexpensive, fast and environmentally friendly alternative to existing methods for quantification of monomeric composition of PHBV.∙ Validation with state of the art GC measurement exhibits excellent agreement over a broad range of PHBV monomer fractions.
Possible semi-circumglobal teleconnection across Eurasia driven by deep convection over the Sahel
Authors: Nakanishi Tomoe , Tachibana Yoshihiro , Ando Yuta 
Published: May 2021

AbstractThe Sahel region, located between the tropical rainforests of Africa and the Sahara Desert, has rainfall that varies widely from year to year, associated with extremely deep convection. This deep convection, strongly heated by water vapor condensation, suggests the possibility of exerting a remote influence on mid- and high-latitude climate similar to the well-known influences of tropical oceanic convection on global climate. Here we investigate the possibility that deep convection over the Sahel initiates a semi-circumglobal teleconnection extending to eastern Eurasia. Statistical analysis and numerical experiments support the possible existence of this teleconnection at an interannual time scale. We propose that the anomalous heat source due to deep convection over the Sahel in the late monsoon season influences meandering of the mid-latitude jet stream over Europe through the combination of a Matsuno-Gill response and advection of absolute vorticity. This subtropical jet meander may in turn drive an eastward propagation of a Rossby wave across Eurasia as far as East Asia. Because deep convection over other subtropical land areas may exert a similar remote influence upon extratropical extreme weather, further studies of the influence of overland convection may provide us with an expanded comprehension of teleconnections.
Digital therapeutics in neurology
Authors: Abbadessa G. , Brigo F. , Clerico M. , De Mercanti S. , Trojsi F. , Tedeschi G. , Bonavita S. , Lavorgna L. 
Published: May 2021

AbstractDigital therapeutics (DTx) is a section of digital health defined by the DTx Alliance as “delivering evidence-based therapeutic interventions to patients that are driven by software to prevent, manage, or treat a medical disorder or disease. They are used independently or in concert with medications, devices, or other therapies to optimize patient care and health outcomes”. Chronic disabling diseases could greatly benefit from DTx. In this narrative review, we provide an overview of DTx in the care of patients with neurological dysfunctions.
Retrograde endovascular revascularization for chronic total occlusion of the internal carotid artery: a case report
Authors: Uno Takeshi , Shojima Masaaki , Oyama Yuta , Yamane Fumitaka , Matsuno Akira 
Published: May 2021

AbstractEndovascular revascularization of a chronically occluded internal carotid artery (ICA) is challenging because the occlusive segment can be long and tortuous. A case is presented of a successful recanalization of a chronically occluded ICA by retrograde passing of a guidewire from the intracranial ICA to the cervical ICA via the posterior communicating artery. This case suggests that a retrograde approach for reopening an occluded artery may be useful during neurovascular interventions, similar to percutaneous coronary interventions. In this patient, daily transient ischemic attacks disappeared after successful recanalization of the ICA.
Regulatory non-coding RNAs: a new frontier in regulation of plant biology
Authors: Bhogireddy Sailaja , Mangrauthia Satendra K. , Kumar Rakesh , Pandey Arun K. , Singh Sadhana , Jain Ankit , Budak Hikmet , Varshney Rajeev K. , Kudapa Himabindu 
Published: May 2021

AbstractBeyond the most crucial roles of RNA molecules as a messenger, ribosomal, and transfer RNAs, the regulatory role of many non-coding RNAs (ncRNAs) in plant biology has been recognized. ncRNAs act as riboregulators by recognizing specific nucleic acid targets through homologous sequence interactions to regulate plant growth, development, and stress responses. Regulatory ncRNAs, ranging from small to long ncRNAs (lncRNAs), exert their control over a vast array of biological processes. Based on the mode of biogenesis and their function, ncRNAs evolved into different forms that include microRNAs (miRNAs), small interfering RNAs (siRNAs), miRNA variants (isomiRs), lncRNAs, circular RNAs (circRNAs), and derived ncRNAs. This article explains the different classes of ncRNAs and their role in plant development and stress responses. Furthermore, the applications of regulatory ncRNAs in crop improvement, targeting agriculturally important traits, have been discussed.
Mathematical Modelling of Residual-Stress Based Volumetric Growth in Soft Matter
Authors: Huang Ruoyu , Ogden Raymond W. , Penta Raimondo 
Published: May 2021

AbstractGrowth in nature is associated with the development of residual stresses and is in general heterogeneous and anisotropic at all scales. Residual stress in an unloaded configuration of a growing material provides direct evidence of the mechanical regulation of heterogeneity and anisotropy of growth. The present study explores a model of stress-mediated growth based on the unloaded configuration that considers either the residual stress or the deformation gradient relative to the unloaded configuration as a growth variable. This makes it possible to analyze stress-mediated growth without the need to invoke the existence of a fictitious stress-free grown configuration. Furthermore, applications based on the proposed theoretical framework relate directly to practical experimental scenarios involving the “opening-angle” in arteries as a measure of residual stress. An initial illustration of the theory is then provided by considering the growth of a spherically symmetric thick-walled shell subjected to the incompressibility constraint.
The Interactions Between Oxide Film Inclusions and Inoculation Particles TiB2 in Aluminum Melt
Authors: Yang Jiawei , Bao Sarina , Akhtar Shahid , Li Yanjun 
Published: May 2021

Abstract
In this work, a systematic study on the interactions between aluminum oxide films and TiB2 grain refiner particles and their effect on grain refinement behavior have been conducted. Oxide films were introduced into a commercial purity aluminum melt by adding AA 6061 alloy chips while the grain refiner particles were introduced by adding Al-3T-1B master alloy. Strong sedimentation of TiB2 grain refiner particles was observed in aluminum melt without chip addition during long-time settling. Most of the TiB2 particles were settled and accumulated at the bottom of crucible. In contrast, the sedimentation of TiB2 particles is much less in the melt with the addition of oxide films. A large fraction of TiB2 particles were found to be adhered to the oxide films located at the top part of the crucible, which inhibited the sedimentation of grain refiner particles. TP-1 type tests were also done to study the grain refinement efficiency of Al-3Ti-1B master alloy under different melt cleanliness and settling time. It is found that sedimentation of TiB2 particles greatly reduces the grain refinement efficiency. The introduction of oxide films seems to slightly alleviate the fading effect. This is owing to the strong adherence between the oxide films and TiB2 particles, which leads to a retardation of particle sedimentation.
Risk of eating disorders in a representative sample of Italian adolescents: prevalence and association with self-reported interpersonal factors
Authors: D’Anna Giulio , Lazzeretti Marco , Castellini Giovanni , Ricca Valdo , Cassioli Emanuele , Rossi Eleonora , Silvestri Caterina , Voller Fabio 
Published: May 2021

Abstract
Purpose
Adolescence represents a critical period for the onset of eating disorders (EDs). The present study aimed to provide the prevalence of individuals at risk for EDs psychopathology in a representative population of adolescents aged 14–19 and to characterize this population regarding interpersonal and psychological factors.

Methods
The percentage of participants at risk for EDs in a representative high school population was assessed through the SCOFF screening questionnaire (cut-off score: 3) in the total sample (N: 6551) and in gender-based subgroups for different body mass index (BMI) categories. Odds ratios for being at risk of ED (SCOFF ≥ 3) were esteemed in a multivariable analysis including self-reported parental education, quality of family and peer relationships, bullying victimization, age at first sexual intercourse, and psychological distress.

Results
A SCOFF score ≥ 3 was found in 31.0% of participants (boys: 19.4%; girls: 44.6%), with a greater prevalence among higher BMI categories. Bad family relationships, being bullied, having the first sexual intercourse before the age of 14, and experiencing high distress were associated with this risk condition. Among girls, bad peer relationships were associated with a low-risk SCOFF score.

Conclusion
A remarkable percentage of adolescents reported significant body image or eating concerns. Screening programs are deeply needed, and particular attention should be devoted to interpersonal factors, such as the quality of family relationships and interactions with peers, which represent potential indicators of this vulnerability.

Level of evidence
Level V – Cross-sectional study.
A Solitary Fetal Cardiac Rhabdomyoma: A Hemodynamically Unstable Left Ventricular Tumor with Autopsy and Histopathology Findings
Authors: Philip Saji , Thampy Linta 
Published: May 2021

AbstractFetal primary cardiac tumors are rare, but they may cause complications which are sometimes life threatening, including arrhythmias, hydrops fetalis, ventricular outflow/inflow obstruction, cardiac failure, and even sudden death in utero. Rhabdomyoma is the most common cardiac tumor in fetuses and is usually diagnosed in the third trimester of pregnancy. It has a benign course in the majority of cases and is often associated with tuberous sclerosis complex. We report a rare solitary large left ventricular tumor, rhabdomyoma with pericardial effusion, causing unstable hemodynamics and threatening intrauterine life with impending nonimmune hydrops. This was confirmed and further described with autopsy and histopathology findings.
Long-term remission of acromegaly after somatostatin analogues withdrawal: a single-centre experience
Authors: Sala E. , Carosi G. , Del Sindaco G. , Mungari R. , Cremaschi A. , Serban A. L. , Ronchi C. L. , Ferrante E. , Arosio M. , Mantovani G. 
Published: May 2021

Abstract
Purpose
A long-lasting remission of acromegaly after somatostatin analogues (SAs) withdrawal has been described in some series. Our aim was to update the disease evolution after SAs withdrawal in a cohort of acromegalic patients.

Methods
We retrospectively evaluated 21 acromegalic patients previously included in a multicentre study (Ronchi et al. 2008), updating data at the last follow-up. We added further 8 patients selected for SAs withdrawal between 2008–2018. Pituitary irradiation represented an exclusion criterion. The withdrawal was suggested after at least 9 months of clinical and hormonal disease control. Clinical and biochemical data prior and after SAs withdrawal were analysed.

Results
In the whole cohort (29 patients) mean age was 50 ± 14.9 years and 72.4% were females. In 69% pituitary surgery was previously performed. Overall, the median time of treatment before SAs withdrawal was 53 months (IQR = 24–84). At the last follow up in 2019, 23/29 patients (79.3%) had a disease relapse after a median time of 6 months (interquartile range or IQR = 3–12) from the drug suspension, while 6/29 (20.7%) were still on remission after 120 months (IQR = 66–150). IGF-1 levels were significantly lower before withdrawal in patients with persistent remission compared to relapsing ones (IGF-1 SDS: -1.5 ± 0.6 vs -0.11 ± 1, p = 0.01). We did not observe any other difference between patients with and without relapse, including SAs formulation, dosage and treatment duration.

Conclusion
A successful withdrawal of SAs is possible in a subset of well-controlled acromegalic patients and it challenges the concept that medical therapy is a lifelong requirement.
Europäische Perspektiven auf den Arbeits- und Gesundheitsschutz: Impulse für eine globaler orientierte Arbeitswissenschaft
Authors: Windel Armin , Haus-Rybicki Sebastian 
Published: May 2021

ZusammenfassungIn den vergangenen Jahrzehnten hat sich die Sicherheit und Gesundheit der Erwerbstätigen in Europa stetig verbessert, was nicht zuletzt auf die Umsetzung arbeitswissenschaftlicher Erkenntnisse zurückzuführen ist. Gleichwohl stehen die europäischen Arbeitsschutzsysteme vor einer Reihe von Herausforderungen, die nicht zuletzt im Zuge der Covid-19-Pandemie verstärkt in das Bewusstsein der Politik und der Öffentlichkeit gerückt sind. Der Beitrag thematisiert beispielhaft einige dieser zentralen Herausforderungen des Arbeitsschutzes aus einer europäischen Perspektive. Grundlage ist ein Positionspapier, das unter Federführung der Bundesanstalt für Arbeitsschutz und Arbeitsmedizin (BAuA) gemeinsam mit den führenden europäischen Arbeitsschutzinstituten aus dem Forschungsnetzwerk PEROSH anlässlich des Konsultationsprozesses der EU-Kommission für eine neue europäische Arbeitsschutzstrategie entstanden ist. In diesem Beitrag geht es dabei nicht nur darum, die europäische Dimension vieler Herausforderungen herauszustellen. Vielmehr skizziert er diese auch als strategische Handlungsfelder, um die Potenziale der Arbeitswissenschaft bezüglich der Erarbeitung gemeinsamer europäischer Lösungsansätze – als Grundlage für die Lösung von Problemen der Globalisierung – hervorzuheben.
Fuzzy rule-based set point weighting for fuzzy PID controller
Authors: Mitra Pubali , Dey Chanchal , Mudi Rajani K. 
Published: May 2021

AbstractThe objective of this work is to design a fuzzy rule-based set point weighting mechanism for fuzzy PID (FPID) controller so that an overall improved closed-loop performance may be achieved for linear as well as nonlinear process models. Till date, tuning criteria for FPID controllers are not well defined. Trial-and-error approach is primarily adopted and it is quite time-consuming and does not always ensure improved overall closed-loop behaviour. Hence, to ascertain satisfactory closed-loop performance with an initially tuned fuzzy controller, a fuzzy rule-based set point weighting mechanism is reported here. The proposed scheme is capable of providing performance enhancement with instantaneous weighting factor calculated online for each instant based on the latest process operating conditions. The proposed methodology is capable of ascertaining acceptable performances during set point tracking as well as load recovery phases. Efficacy of the proposed scheme is verified for linear as well as nonlinear process models through simulation study along with real-time verification on servo position control in comparison with the others’ reported performance augmentation schemes as well as fuzzy sliding mode control.
Analysis and modeling of the thermal behavior of an improved pellet cookstove
Authors: Vitoussia Théophile , Brillard Alain , Bertsch Justin , Allgaier Olivier , Leyssens Gontrand , Schönnenbeck Cornélius , Njeugna Ebenezer , Brilhac Jean-François 
Published: May 2021

AbstractIn Sub-Saharan countries, cooking is usually done at a domestic scale using rudimentary stoves with wood or charcoal as combustibles. To improve the cooking behavior and reduce the deforestation, an improved pellet cookstove was conceptualized with guiding ideas in mind such as simplicity, robustness and ability to burn pellets built with local wood residues under a natural draught. Combustion and water ebullition tests were performed with two configurations of the upper part of the cookstove: thick steel plate or ring, and with standardized EN+ pellets as combustible. The main pollutant gases (CO, CO2 and NOx), together with O2, were continuously measured at different positions of the cookstove during a water ebullition test with the ring configuration. The levels measured above the pot were lower than the thresholds currently proposed by the World Health Organization. Simple and phenomenological thermal models were proposed to simulate the plate, or ring, and water temperatures during the combustion or water ebullition tests and to determine the intrinsic convection coefficients. The maximal relative differences between the experimental and simulated temperatures were computed between 7 and 21%. The stove power was evaluated at 4336 ± 23 W. The cookstove yield for the water ebullition test with the ring configuration was computed equal to 12.3 ± 0.1%, slightly lower than that of cookstoves previously analyzed in the literature.