bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sustainable Approaches for Managing Phthalate Pollution: Navigating Challenges, and Establishing the Future of Environmental Protection
Authors: Marcharla Eswar , Chauhan Smarika , Hariharan Sneha , Punniyakotti Parthipan , Sundaram Thanigaivel , Ganesan Swamynathan , Kim Woong , Govarthanan Muthusamy 
Published: December 2024

AbstractPhthalates have become a widespread environmental pollutant that has severe implications for aquatic and terrestrial ecosystems. They are found in various sources, including industrial processes, consumer products, and food packaging, resulting in significant environmental contamination. Their persistence and ability to bioaccumulate present significant risks, especially impacting reproductive, developmental, and endocrine systems in humans. This review explores how phthalates function as mixed micropollutants, adding complexity to their evaluation and control in environmental systems. It also focuses on remediation strategies using novel biotechnological approaches, such as enzymatic degradation, genetic engineering, microbial remediation, and nanotechnology‐based approaches. Enzymatic degradation utilizes specific enzymes for the breakdown of phthalates, thereby, transforming them into less toxic metabolites. Novel genetic engineering techniques have opened possibilities for improving the breakdown of phthalates by microorganisms, offering potential solutions for more efficient remediation. Nanotechnology‐based approaches showcase the effectiveness of nanomaterials in absorbing and breaking down phthalates on a molecular scale. This review also highlights the importance of microbial consortia and biochar‐microbial composites for environmental restoration. The unique contribution of this review lies in its comprehensive analysis of advanced biotechnological strategies for phthalate remediation, emphasizing the synergistic potential of novel techniques to protect and safeguard the environment for future generations.
Modifying the Electronic and Magnetic Properties of ZrO2${\rm ZrO}_{2}$ Monolayer Through Sp Doping: A First‐Principles Study
Authors: Thuy Huynh Thi Phuong , Van On Vo , Guerrero‐Sanchez J. , Hoat D. M. 
Published: December 2024

AbstractDesigning 2D materials for multifunctional applications becomes increasingly important because of the development of diminutive devices. In this work, doping with non‐transition metals (M@ systems; M = Na, Mg, Al, and Si) and nonmetals (X@ systems; X = B, C, N, and F) is proposed to modify the electronic and magnetic properties of monolayer. Pristine monolayer is a 2D insulator with a large bandgap of 4.40(6.08) eV obtained from standard(hybrid)‐based calculations. The monolayer is magnetized with total magnetic moments of 3.00, 2.00, and 1.00 upon doping with Na, Mg, and Al metals, respectively. In these cases, magnetic properties are produced mainly by O atoms around doping sites. Meanwhile, Si doping induces no magnetism in monolayer, preserving its nonmagnetic nature. However, the bandgap suffers from a large reduction of the order of 22.27%. The monolayer magnetization is also achieved by doping with B, C, N, and F atoms, where total magnetic moments of 3.00, 2.00, 1.00, and 0.97 are obtained, respectively. For ‐type doping cases, nonmetal impurities produce mainly magnetic properties, meanwhile, Zr atoms generate mainly the magnetism of F‐doped monolayer. Interestingly, feature‐rich half‐metallic nature (in Na@, Mg@, C@, and F@ systems) and magnetic semiconductor nature (in Al@, B@, and N@ systems) are also obtained. By analyzing Bader charge, the roles of charge loser and charge gainer are confirmed for non‐transition metal and nonmetal impurities, respectively. The results may introduce new 2D materials suitable for spintronic applications.
Examining the Impact of Row Planting on Labor Use for Sustainable Food Production Among Maize Farmers in Rural Ghana
Authors: Jumpah Emmanuel Tetteh , Alem Habtamu , Adams Abdulai , Ratinger Tomáš , Bavorová Miroslava 
Published: December 2024

ABSTRACTSmallholder farmers are reverting to traditional production methods due to the high opportunity costs and unintended consequences of new technologies. This study focuses on row planting technology, which is labor‐intensive and slow without mechanized operations. Data from 224 nonadopters and 237 adopters of row planting were analyzed using ordinary least squares and instrumental variable techniques. The results show varying effects of row planting on yield and income across different agroecological zones, with labor use being endogenously determined. Comparing labor requirements, we found that row planting demands an additional 14.79 man‐hours per acre over broadcasting seeds. The current dissemination approach of sustainable intensification technologies such as row planting prioritizes yield‐enhancing technologies over mechanization, hindering adoption. We propose integrating small‐scale mechanization, such as small‐scale planters and harvesters, to reduce labor hours and promote sustainable intensification technology adoption.
Encapsulation of Pt species into MFI zeolite with tunable acid sites boosts reductive amination towards tertiary amines
Authors: Xiong Zhuo , Meng Biao , Chen Cailing , Liu Xiaoling , Wu Chao , Wu Yue , Xu Meng , Xu Hongzhong , Dai Yihu , Han Yu , Zhou Yu , Xi Shibo , Wang Jun 
Published: December 2024

AbstractNoble metal‐catalyzed reductive amination of carbonyl compounds using molecular hydrogen is a promising green route for amine synthesis, but a challenge remains to boost the atomic efficiency of noble metal species. Herein, MFI zeolite encapsulated Pt species with tunable Si/Al ratios were synthesized to allow the formation of Pt nanoparticles (NPs) with almost the same loading amount, particle size, and electronic state. Confining Pt NPs allows the spatial satisfaction for the synergy of metal centers and acid sites, and Pt@ZSM‐5(100) with a moderate Si/Al ratio performed high efficiency in the conversion of carbonyl compounds and boosted high TOF of 23,409 h−1 in reductive amination of benzaldehyde. Combined with structure refinement, x‐ray absorption fine structure (XAFS), in situ Fourier transforms infrared (FTIR) spectroscopy, and theoretical calculation, the study indicated that modulating the Si/Al ratio enables the fine rationalization of the microenvironment. The moderate Si/Al ratio causes suitable acid intensity that significantly contributes to the carbonyl compound activation and product desorption.
Particle Acceleration in Solar Flares From Radio and Hard X‐Ray Spectra
Authors: Valio Adriana , da Silva Douglas F. , Li Hui 
Published: December 2024

ABSTRACTFor a deeper understanding of the physical processes at play in solar flares, it is necessary to analyze the flare emissions at multiple wavelengths. This multifrequency approach enables the characterization of energetic electrons accelerated from hundreds of keV and up to several tens of MeV. This study reports on the observation of 10 solar flares, in which the spectral parameters were determined for the cm/mm and x‐ray bands. The radio spectrum was fitted using gyrosynchrotron emission whereas the hard x‐rays fit considered a model of thermal plus nonthermal emission of accelerated electrons. The results show that the spectral indices of the energy distribution of nonthermal electrons emitting in millimeter and hard x‐rays do not agree, with the millimeter spectral index being approximately 2 units harder than that of hard x‐rays. These findings are consistent with previous research and suggest the existence of a break in the energy spectrum of accelerated electrons. Moreover, for the only flare where photons exceeding 1 MeV were detected, the hard x‐ray spectra exhibited a broken power‐law where the index of the electron distribution above ~500 keV agreed with the inferred radio spectral index.
Structural Fellowships do Cardiology Fellows a Disservice
Authors: Schwartz Bryan G. 
Published: December 2024

Summary

Growth of new TAVR programs has slowed significantly in recent years.
Dedicated structural fellowship opportunities continue to increase.
Most job opportunities for interventional cardiology remain in coronary interventions, not structural interventions.
Interventional cardiology fellows are best served by completing interventional fellowship in 1 year as opposed to pursuing a dedicated structural year.
Immediate Use of Impella CP for High‐Risk Percutaneous Coronary Intervention After Repair of Thrombosed Aortic Coarctation
Authors: Jiménez‐Rodriguez Gian Manuel , Garcia‐Montes José Antonio , Eid Lidt Guering , Solis‐Jimenez Fabio 
Published: December 2024

ABSTRACTAortic coarctation represents up to 7% of congenital heart diseases and is associated with hypertension and coronary artery disease, which continues to be the leading cause of death even after successful surgical repair. However, there is limited knowledge of managing both conditions, especially in the setting of an acute coronary syndrome. We herein present the case of a 53‐year‐old man with a history of hypertension who initially presented with an ST‐elevation myocardial infarction successfully treated with thrombolysis and hemodynamic compromise. During angioplasty, an incidental finding of aortic coarctation was noted. After a thorough evaluation by the heart team, it was determined that percutaneous revascularization with ventricular support was necessary due to the high surgical risk. Aortic coarctation repair was performed first, followed by successful angioplasty with the placement of an Impella CP device through the newly implanted aortic stent. To our knowledge, this is the first reported case of a patient with both STEMI and aortic coarctation treated sequentially and using only a percutaneous approach. It is also the first reported case where a ventricular assist device (VAD) was used to support high‐risk PCI in a patient with a repaired aortic coarctation.
The small molecule peptide ANXA114‐26 inhibits ovarian cancer cell proliferation and reverses cisplatin resistance by binding to the formyl peptide receptors receptor
Authors: Li Nana , Yan Peihua , Guo Ling , Wang Huiyan , Cui Baohong , Teng Lichen , Su Yajuan 
Published: December 2024

AbstractChemo‐resistance in ovarian cancer is currently a major obstacle to the treatment and recovery of ovarian cancer. Therefore, identifying factors associated with chemo‐resistance in ovarian cancer may reverse chemo‐sensitization. Using isobaric tags for relative and absolute quantitation (ITRAQ) technology, we found a small molecule peptide with annexin 1 (ANXA1) as a precursor protein. Then, we explored the effects and mechanisms of this small molecule peptide on the proliferation, apoptosis, and drug resistance of ovarian cancer resistant cells through CCK‐8, EdU cell proliferation assay, Annexin V‐FITC/PI assay, Western blot,qRT‐PCR. ANXA114‐26 was highly expressed in the serums of sensitive patients. ANXA114‐26 promoted apoptosis of ovarian cancer cells and increased the sensitization of ovarian cancer cells to cisplatin. The ANXA114‐26 and ANXA1 competitively bind formyl peptide receptors (FPR). ANXA114‐26 decreased multidrug resistance‐associated protein 1 (MRP1) expression in ovarian cancer cells through the FPR/Cyclin D1/NF‐ĸBp65 pathway. We found a peptide derived named ANXA114‐26 in the serum of ovarian cancer patients. It can reduce ovarian cancer cell proliferation and reduce MRP1 expression through the FPR/Cyclin D1/NF‐ĸBp65 pathway.
A Case of Fibrolamellar Hepatocellular Carcinoma in Which Tumor Control Was Achieved by Re‐Administering Atezolizumab and Bevacizumab
Authors: Hagiwara Satoru , Oda Itsuki , Ueshima Kazuomi , Komeda Yoriaki , Nishida Naoshi , Yoshida Akihiro , Yamamoto Tomoki , Omaru Naoya , Matsubara Takuya , Kudo Masatoshi 
Published: December 2024

ABSTRACTBackgroundFibrolamellar hepatocellular carcinoma (FL‐HCC) clinically occurs in young people aged 20–30 years, who often have a normal liver background. We propose a treatment for such cases in which a combination therapy of atezolizumab and bevacizumab is followed by sandwiching radiation therapy to release tumor antigens and then re‐administering the combination therapy of atezolizumab and bevacizumab (ABC conversion therapy).CaseThe patient is a 15‐year‐old girl. On April 18, 2022, she noticed skin yellowing and visited her local doctor. Computed tomography (CT) revealed a large mass in the right lobe of the liver and bile duct obstruction due to the tumor. She also had a nodule on her chest that appeared to be a metastatic tumor and was referred to Kinki University Hospital in April 2023. She was suspected to have FL‐HCC based on contrast‐enhanced ultrasound and CT scan results. There were findings suggestive of lung metastasis; however, she underwent a right hepatic lobectomy on May 17, 2023, considering the risk of liver failure and intra‐abdominal bleeding due to the large liver tumor. A CT scan conducted on July 25, 2022, showing increased lung metastases, and she started atezolizumab/bevacizumab combination treatment on October 20, 2022. On March 15, 2023, multiple lung metastases and new intrahepatic lesions appeared, which was diagnosed as progressive disease (PD), and lenvatinib was discontinued. On November 17, 2023, radiation therapy (25 Gy/5 Fr) was administered to the lung and intrahepatic lesions to release tumor antigens, and on November 27, 2023, atezolizumab and bevacizumab combination treatment was resumed to control the tumor.ConclusionCombination therapy with atezolizumab, bevacizumab, and radiation therapy may be an option for the treatment of FL‐HCC.
Mixed clastic‐carbonate lake margin systems: An example from the Triassic of East Greenland
Authors: Andrews Steven D. , Guo Li 
Published: December 2024

AbstractLake margin deposits are the subject of increased study, but this is often focussed on either clastic or carbonate/microbial dominated end members. This study examines the interaction of clastic and carbonate systems. The Upper Triassic Edderfugledal Formation in East Greenland provides superb exposures through a carbonate dominated lacustrine succession. Fluctuations in lake level, interpreted as a response to cyclic, orbitally forced, climatic variance resulted in a highly mobile lake shore zone. The response of the shore zone environment to these fluctuations in lake level, and the interaction of both clastic and carbonate components, are documented in this study. A general trend from more arid to more humid conditions is recognised through the Edderfugledal Formation. This trend is reflected in a transition from more ephemeral lacustrine conditions with low sediment input to conditions where lacustrine episodes were more prolonged and clastic input was increased. Deposits reflecting more ephemeral conditions are dominated by extensive post‐depositional disruption including desiccation, pedogenic processes and evaporite precipitation. These effects increase towards the lake margins where exposure was most common and most prolonged. Increasingly humid conditions and the associated longer‐lived lacustrine developments and increased clastic sediment input resulted in a very different form of lake margin. During transgressive phases sediment input was pushed back to the lake margin allowing extensive microbialite development. Ooidal shoals developed in shallow water beyond the extent of clastic input. The lakeward migration of the ooidal shoals and the progradation of clastic systems eventually stifled the microbialites prior to the next transgressive event. In a mixed clastic‐carbonate lacustrine setting the interaction of sediment supply and production are key factors in governing facies development and these are in turn predominantly controlled by lake‐level change and lake margin bathymetry.
Short‐ and Long‐Term Swallowing Outcomes in Head and Neck Cancer Patients Receiving TORS and Adjuvant Therapy
Authors: Weiland Abigail C. , Samant Sandeep , Clain Alex E. , Martin‐Harris Bonnie 
Published: December 2024

ABSTRACTBackgroundDysphagia (difficulty swallowing) is a common morbidity resulting from the treatment of head‐and‐neck squamous‐cell carcinoma (HNSCC) due to surgery and chemoradiation. Transoral robotic surgery (TORS) is a minimally invasive surgical technique for the management of HNSCC, which ideally avoids many of the known complications of open surgery. Research describing physiologic swallowing impairment after surgery using videofluoroscopy is lacking.MethodsWe evaluated videofluoroscopic swallowing studies of 37 patients who received TORS for head and neck cancer using a validated scoring tool, the Modified Barium Swallow Impairment Profile (MBSImP), at three time points including baseline.ResultsPatients had worsened physiologic impairments in the immediate post‐operative and late post‐operative periods, particularly in components related to airway protection. Many patients also had baseline swallowing impairment.ConclusionsFurther research is required to elucidate dysphagia at discrete time points before and after treatment as well as with different and evolving adjuvant therapy protocols.
A Learning Model with Memory in the Financial Markets
Authors: Singh Shikta , Chandrasena Supun , Shi Yue , Alhussaini Abdullah , Diebolt Claude , Enilov Martin , Mishra Tapas 
Published: December 2024

ABSTRACTLearning is central to a financial agent's aspiration to gain persistent strategic advantage in asset value maximisation. The implicit mechanism that transforms this aspiration into an observed value gain is the speed of error corrections (demonstrating, an agent's speed of learning) whilst facing increased uncertainty. In such a setting, perpetual learning can lead to a type of memory that financial agents can exploit as an information set to plan for their next strategic decisions. The existing literature focuses predominantly on a learning model with a long‐lag characterisation of asset values. However, recent methodological advances show that long memory can be generated from a learning model with just one lag. In this paper, we exploit this strand of literature and integrate the new construct into our proposed duration‐compliant ‘social distance’ mechanic as an alternative robust model of learning in a financial market. We assess the efficacy of our approach with a numerical example and a calibration exercise.
Measurement of thiol/disulfide homeostasis and ischemic modified albumin levels in patients with uterine leiomyomas
Authors: Akcan Bengü Nur Bariş , Yikilmaz Büşra Karagöz , Zorlu Uğurcan , Erel Özcan , Neşelioğlu Salim , Özyurt Esra , Tekin Özlem Moraloğlu , Elmas Burak 
Published: December 2024

AbstractObjectiveThe aim is to contrast the serum levels of thiol‐disulfide homeostasis and ischemic modified albumin between patients with leiomyoma and healthy individuals and to assess the impact of oxidative stress on the etiopathogenesis of leiomyoma.MethodsIn this prospective case‐control study, a total of 154 participants were included, consisting of 77 cases diagnosed with leiomyoma and 77 healthy individuals without leiomyoma. The demographic characteristics and ultrasonographic findings of the participants were recorded, and parameters such as albumin, ischemia‐modified albumin, and thiol‐disulfide homeostasis were evaluated. The results obtained from the analyses were compared between the two groups.ResultsNo significant differences were observed in the demographic characteristics between the groups. A significant difference was observed between the leiomyoma and control groups regarding serum albumin parameters, serum ischemic modified albumin, and serum dynamic thiol‐disulfide parameters (P < 0.001). No significant difference was found in the ratios of disulfide/total thiol, disulfide/native thiol, native thiol/total thiol (P > 0.05).ConclusionThere was a notable contrast in the levels of albumin, ischemic modified albumin, albumin/ischemic modified albumin ratio, total thiol, native thiol, and disulfide between individuals with uterine leiomyomas and healthy individuals in the control group. Oxidative stress is believed to play a causative role in the etiopathogenesis of uterine leiomyomas.
The development of the Promoting First Relationships home visiting program and caregivers’ comments about their experiences across four RCT studies
Authors: Oxford Monica , Abrahamson‐Richards Tess , O'Leary Rae , Booth‐LaForce Cathryn , Spieker Susan , Lohr Mary Jane , Rees Jennifer , Kelly Jean 
Published: December 2024

AbstractPromoting First Relationships (PFR) is an evidence‐based home‐visiting program for caregivers and their children from birth to age 5 years. It focuses on caregiver–child interaction, attachment, and relationship quality using video feedback of unedited recordings to elicit reflection and provide positive feedback linked to knowledge development. This paper provides a brief history of PFR and reports on a qualitative study of 222 caregivers’ comments about their PFR experiences following participation in one of four randomized controlled trials conducted over the past decade in the United States (two studies within child welfare setting, one study with Native American families, and one study with Spanish and English‐speaking mothers), using a thematic analysis approach to code excerpts from written satisfaction surveys and oral satisfaction interviews. Caregivers’ comments about PFR were positive and were classified into four major thematic areas: a caring, trusting relationship with the provider; enthusiastic program endorsement; improved relationship with their child; and reports of their personal growth and development. The qualitative results align with the key components of the PFR program and confirm aspects of the PFR theory of change model.
School counseling district leaders’ experiences with anti–DEI laws and policies: A phenomenological investigation
Authors: Goodman‐Scott Emily , Sampson Darrell J. , Johnson Kaprea F. , Sawyer‐Mays DeHaven 
Published: December 2024

AbstractSchool counseling district leaders (SCDLs) are instrumental in shaping district policy, supporting school counselors, and interfacing with both internal and external constituents; as such, their systemic lens is of particular importance, given the K‐12 pushback on diversity, equity, and inclusion (DEI) occurring at the state‐ and district‐levels. As a result, we conducted a critical application of Husserl's phenomenology to understand the collective experience of a sample of SCDLs (N = 10) working in locations with anti‐DEI laws and/or policies, specifically those restricting Black, indigenous, and people of color and lesbian, gay, bisexual, transgender, and queer/questioning rights and topics. Through the findings, participants shared that navigating the anti‐DEI systems resulted in increasingly complex leadership roles, overcoming fear to recommit to their students and professional values, and finally, combating anti‐DEI efforts through advocacy. Recommendations for future practice and research are included and grounded in a multi‐systemic approach and advocacy.
Comprehensive Analysis of Deuterium Isotope Effects on Ionic H3O+…π Interactions Using Multi‐Component Quantum Mechanics Methods
Authors: Udagawa Taro , Kanematsu Yusuke , Ishimoto Takayoshi , Tachikawa Masanori 
Published: December 2024

ABSTRACTDeuterium isotope effects on interaction energies and geometrical parameters in several H3O+(D3O+)…ene and H3O+(D3O+)…yne complexes, which involve O‐H(D)…π interactions, have been analyzed using the MP2 level of the multi‐component molecular orbital method (MC_MP2), which can incorporate the nuclear quantum effects of light nuclei, such as protons and deuterons. The MC_MP2 calculations revealed that D3O+ replacement reduced the interaction energies of the complexes and induced changes in geometrical parameters. In addition, natural energy decomposition analysis (NEDA) revealed a strong correlation between the H/D isotope effects on the H/D…π distances and on each energy component.