bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sublethal Effects of Propiconazole On The Metabolism of Lambari Deuterodon Iguape (Eigenmann 1907), A Native Species From Brazil
Authors: Henriques Marcelo Barbosa , Rezende Karina Fernandes Oliveira , Castilho-Barros Leonardo , Barbieri Edison 
Published: February 2021

Abstract
The objective of this study was to analyze the sublethal effects of propiconazole on Deuterodon iguape a native fish common in Brazil, which has potential for aquaculture and use as a bioindicator. The hypothesis was to test whether D. iguape has a metabolism similar to Danio rerio so that its use in bioassays may be validated. Lethal concentration (LC50) and metabolic rates were studied in fish exposed to propiconazole. There was an increase and decrease in the metabolic rate at 0.01 and 0.1 µg L-1, with a statistical difference from the control ratio for the two species. The same trend towards ammonia excretion was observed, initially increasing to a concentration of 0.01 µg L-1 and then decreasing as the concentration of propiconazole was increased. The averages of specific ammonia excretion in all concentrations were significantly different compared to the control. It was concluded that exposure to propiconazole increased the metabolic rates of D. Iguape and D. rerio, up to 0.05 µg L-1, and decreased the rates when the concentration was doubled (0.1 µg L-1); causing serious problems in fish metabolism. D. iguape proved to be a good and useful bioindicator for ichthyologists or ecologists in studies of moderate pesticide contamination in freshwater aquatic environments, as its metabolic response was similar to D. rerio.
Synergistic effect of titanium dioxide (TiO2) and ionizing radiation on thermal and mechanical properties of carboxymethyl cellulose (CMC) for potential application in removal of basic dye from wastewater
Authors: Gad Yasser , Ali Hussein E. , Hegazy El-Sayed A. 
Published: February 2021

Abstract
Carboxymethyl cellulose (CMC)/titanium dioxide (TiO2) was prepared using gamma irradiation at different doses. Carboxymethyl cellulose was used as a matrix and TiO2 in different contents was added (0.25, 0.5, 1, 1.5 wt %) as a filler. The polymer composite film were irradiated at doses of 5, 10 and15 kGy using 60Co γ-ray to form crosslinked network structure. The prepared composite films were described by different diagnostic procedures including X-ray diffractometer, scanning electron microscope (SEM), FTIR as well as thermal and mechanical properties measurements. CMC/TiO2 composite films was used for removal of basic Violet 7 dye. The adsorption of the dye follows the Langmuir model a with chemical monolayer adsorption behavior. Adsorption kinetic of dyes was set up to be regular to pseudo second order kinetic model. The results showed that the prepared composite films significantly removed this basic violet 7 dye with maximum absorption capacity (123.6 mg/g).
Synergistic effect of titanium dioxide (TiO2) and ionizing radiation on thermal and mechanical properties of carboxymethyl cellulose (CMC) for potential application in removal of basic dye from wastewater
Authors: Gad Yasser , Ali Hussein E. , Hegazy El-Sayed A. 
Published: February 2021

Abstract
Carboxymethyl cellulose (CMC)/titanium dioxide (TiO2) was prepared using gamma irradiation at different doses. Carboxymethyl cellulose was used as a matrix and TiO2 in different contents was added (0.25, 0.5, 1, 1.5 wt %) as a filler. The polymer composite film were irradiated at doses of 5, 10 and15 kGy using 60Co γ-ray to form crosslinked network structure. The prepared composite films were described by different diagnostic procedures including X-ray diffractometer, scanning electron microscope (SEM), FTIR as well as thermal and mechanical properties measurements. CMC/TiO2 composite films was used for removal of basic Violet 7 dye. The adsorption of the dye match with the Langmuir model across chemical monolayer adsorption performance. Adsorption kinetic of dyes was set up to be regular to pseudo second order kinetic model. The results showed that the prepared composite films significantly removed this basic violet 7 dye with maximum absorption capacity (123.6 mg/g).
Temporal and spatial variation of hydrochemical contamination in a former radium-uranium tailing dam as a result of environmental remediation field works
Authors: Barbosa Sofia , Pinto Mariana , Almeida J. A. , Carvalho E. , Diamantino C. 
Published: February 2021

Abstract
The main objective of this work was to understand the evolution of water quality within a tailings dam of a former radium-uranium mining site as a response to environmental remediation works. For this, results of numerical groundwater modeling were combined with multivariate hydrochemical trend analysis derived multivariate Principal Component Analysis and K-means clustering analysis. Numerical groundwater models were developed with the aim of detecting the main flow paths inside the tailings dam and across its bordering. These models allowed the identification of the hydrodynamic flows in the area that are most likely to be directly responsible for relevant hydrochemical exchanges in time. The spatial evolution of the contamination plume in time was mapped considering a cumulative interpretation that integrates all the hydrochemical indicators simultaneously through multivariate and clustering analysis. Resulting hydrochemical maps were superposed with the flow paths identified from modelling allowing to conclude that the contamination plume migrates within the tailings in the dependence of the main water flow paths that percolates within the tailings dam due to the existence of old shafts and old pre-existing streamlines located underneath the tailings dam. The methodology adopted allowed the verification of a general improvement in groundwater quality with a spatial reduction of the contamination plume within the tailings dam.
Incidence and Survival of Thyroid Cancer with Lung Metastasis
Authors: Zhong Miaochun , He Xianghong , Cui Lingfei , Lei Kefeng 
Published: February 2021

Abstract
Background: Thyroid cancer (TC) is common malignancy. Lung metastasis is one of the top metastases for TC. The incidence and survival rates of TC with lung metastasis remains unclear.Methods: Data on TC with lung metastasis and other site-specific metastases were extracted from the Surveillance, Epidemiology, and End Results (SEER) database. The chi-square tests were employed to compare the clinicopathological characteristics among patients with different sites of metastases. Kaplan-Meier analysis and log-rank tests were used for survival analysis. A Cox proportional model was used for multivariate analyses of the patient population. Statistical significance indicated by a two-tailed P value < 0.05. Results: A total of 77322 patients with TC and known sites of distant metastases were identified from 2010-2016. The probability of isolated lung metastasis was significantly higher than that of isolated distant metastasis to other sites among TC patients (P < 0.05). Patients with isolated lung metastases had worse overall and thyroid cancer-specific survival compared to patients with isolated bone metastases (P < 0.05). There was a slight difference in thyroid cancer-specific survival between patients with lung metastasis and patients with liver metastasis(P=0.0496), while there was no significant difference in overall survival. (P >0.05). There was no significant difference in overall survival or thyroid cancer specific survival between patients with lung metastasis and those with brain metastasis (P > 0.05). Multivariate analysis revealed that white race was associated with better outcomes in terms of both endpoints in the lung metastasis population.Conclusions: The incidence of lung metastasis from TC was higher than that of other organ metastases. Thyroid cancer patients with isolated lung metastases have worse outcomes compared to patients with isolated bone metastases and liver metastases, whereas is similar to brain metastasis. There was the worst survival outcome on patients with multi-organ metastases.
The Relationship Between Coronavirus Anxiety Level and Emotional Eating in Individuals with Metabolic Syndrome: A Comparative Study
Authors: Değirmenci Duygu Mataracı , Uğurlu Yasemin Kalkan , Alemdar Dilek Küçük 
Published: February 2021

Abstract
BackgroundThe aim was to determine the coronavirus anxiety levels and emotional eating status of cases with diagnosis of MetS according to diagnostic criteria published by the International Diabetic Federation (IDF) in 2005 and healthy individuals with similar BMI to MetS subjects. MethodsThis study was completed with the descriptive, cross-sectional, case-controlled and relational screening model. The full sampling method was used in the study. The study was completed with 105 individuals with metabolic syndrome attending the diet clinic and 109 healthy individuals without MetS diagnosis also attending the diet clinic. Collection of data used anthropometric measurements and biochemical findings, blood pressure and a survey form, the Coronavirus Anxiety Scale (CAS) and Emotional Eating Scale (EES). ResultsCoronavirus anxiety scale scores of individuals with metabolic syndrome were found to be statistically significantly higher than the scores of the healthy control group (p <0.05). The difference between the metabolic syndrome group and the healthy control group for emotional eating scale scores was not significant (p <0.05)When groups are compared, apart from HDL, blood pressure and all other biochemical parameters were higher in metabolic syndrome subjects (p<0.05). However, when the correlation between coronavirus anxiety scale and emotional eating scale points is investigated in metabolic syndrome and healthy individuals, there was no correlation between the two scales (p>0.05).ConclusionIndividuals with metabolic syndrome had higher coronavirus anxiety levels than healthy individuals; however, there was no difference between metabolic syndrome and healthy subjects in terms of emotional eating behavior.Level of evidenceIII, case–control analytic study.
Seismic Response of Base-Isolated Buildings With High Damping Rubber Bearings Having Different Design Characteristics
Authors: DERİNGÖL Ahmet Hilmi , Güneyisi Esra Mete 
Published: February 2021

Abstract
In this study, the use of high damping rubber bearing (HDRB) with various design properties in mitigating the seismic effects for steel buildings was investigated. For this, a generalized demand on the analytical model of HDRB was introduced and eighteen different models of HDRB were examined comparatively. These models were created by considering three significant isolation parameters of HDRB such as isolation period T (2, 2.5, and 3 s), effective damping ratio βeff (0.05, 0.10, 0.15), and post-yield stiffness ratio λ (3 and 6). The benchmark low (3-storey), mid (6-storey), and high-rise (9-storey) steel buildings were equipped with different isolation systems of HDRB and then subjected to a set of earthquake ground motions through nonlinear time history analyses in order to evaluate the actual nonlinear behaviour of the bearings in the base-isolated steel buildings in service. The base-isolated frames were assessed by the variation of the selected structural response parameters such as isolator displacement, relative displacement, inter-storey drift ratio, absolute acceleration, base shear, base moment, hysteretic curve, and dissipated energy. The effectiveness of the steel buildings with HDRB was evaluated. It was shown that the seismic performance of the base-isolated structure was remarkably influenced by the isolation parameters. The higher value of the isolation period and effective damping ratio tended to increase the amount of dissipated energy associated with low post-yield stiffness ratio.
Analysis of Credit Access and Utilization Among Poultry Farmers in Nigeria
Authors: Afolayan Ayodeji , Omisope E. T. , Ajayi Adedamola M. , Adeoti Oluwafemi Samuel , Ogunjinmi Oluwatoyin F. 
Published: February 2021

Abstract
This study assessed credit access and utilization among poultry farmers and its determinant. Primary data were analyzed from 78 farmers using multistage sampling technique using descriptive statistics, logit and multiple regression models. Findings from the study showed that majority of the respondents were in their active age and 75.6 percent of the poultry farmers were males. Majority (83.3 percent) of the respondents were married and educated. Majority was also in their active age (37.2 percent). The factors determining farmers’ decision to use credit which were significant at 5 percent include; number of years spent in school, farm income, labour cost, cost of feeds and sources of capital while only interest rate was significant at 1 percent. Factors that influenced the credit utilization by the farmers in the study area at 5 percent significance level include; farm income, cost of feeds, and number of birds. It is recommended that subsidization of cost of feeds, usage of family labour, and provision of loan at no or low interest rate should be employed in the study area.
A Potent Peroxidase from Solid Cell Culture of Ocimum Basilicum with High Sensitivity for Blood Glucose Determination
Authors: Mohammadnejad Parvin , Asl Saeed Soleimani , Rasoulian Zahra , Aminzadeh Saeed , Ghashghaie Jaleh , Haghbeen Kamahldin 
Published: February 2021

Abstract
Objectives Extensive applications of peroxidase (POX) have raised the global market demand at a considerable rate during the forecast period of 2020 - 2025. Nonetheless, the large-scale POX preparation still relies on the extraction from agricultural products, while there is an accumulative driving force toward employing biotechnological processes with agricultural hassle free identity. In pursuit of this trend; Results, A novel heme peroxidase was purified to homogeneity (MW of 40 kD) from the callus culture of Ocimum basilicum L. in darkness on Murashige-Skoog medium supplemented by 2,4-dichlorophenoxyacetic acid (10-6 M) and kinetin (10-5 M). The highest activity of the purified peroxidase (ObPOX) was observed in Tris-base buffer at pH 7.5 and 80 °C. ObPOX showed high stability over pH(s) 5 to 7.5 and temperatures of 15 to 60 °C. ObPOX specific activity was 1245.142 AU mg-1 in the presence of phenol, 4 times higher than that of HRP. ObPOX showed moderate affinity for guaiacol (Km = 21.5 mM), but obtained an exceptionally high specificity constant (kcat/Km = 66743.7 s-1M-1) for GASA (4-[(4-Hydroxy-3-methoxyphenyl) azo]-benzenesulfonic acid), the introduced substrate for determination of blood sugar. Applying ObPOX instead of HRP in glucose measurements of the real samples improved the regression constant of the correlation diagram between the tests and the lab results from 0.958 to 0.981. Conclusion Physicochemical properties of ObPOX as well as the growth rate of basil callus (5.04 g L-1 per day) and the yield of ObPOX production (35 mg per 100 g dry biomass per subculture) designates O. basilicum cell culture for large-scale production of a robust peroxidase.
Antidiabetic Activity of Phytosynthesized Ag/CuO Nanocomposites Using Murraya Koenigii and Zingiber Officinale Extracts
Authors: Selvan D. Arumai , Kumar R. Senthil , Shobana S. , Murugesan S. , Rahiman A. kalilur 
Published: February 2021

Abstract
In this paper, we report the phytosynthesis of Ag/CuO nanocomposites (NCs) using Murraya koenigii and Zingiber officinale green extracts containing unique metabolites. The silver and copper oxide nanoparticles, and Ag/CuO NCs were also synthesized by chemical methods for the purpose of comparison with phytosynthesized Ag/CuO NCs. All the synthesized nanomaterials were characterized by diverse spectro-analytical methods. The phytochemical analysis confirmed the presence of active phytoconstituents in the Murraya koenigii and Zingiber officinale extracts. The major biomolecules present in the plant extracts act as reducing and capping agents in the green synthesis process, as identified using FT IR spectroscopy. The maximum absorbance at ~ 290 and ~ 460 nm corresponding to CuO and Ag evidenced the formation of Ag/CuO NCs. Further, the XRD patterns also confirmed the formation of nanocomposites by exhibiting the fcc crystalline and monoclinic nature of Ag and CuO nanoparticles, respectively. The SEM images displayed the spherical shape of the synthesized NCs, and the EDX spectra confirmed the presence of Ag, Cu and O elements in the synthesized NCs. The TEM images revealed the relatively uniform size of the synthesized nanomaterials ranging between 18 and 22 nm. The in vitro antidiabetic activity with α-amylase, α-glucosidase and glucose-6-phosphatase enzymes, and glucose uptake assay showed that the Ag/CuO NCs synthesized using Zingiber officinale extract displayed highest activity than the rest of the synthesized nanomaterials.
Efficacy of Endoscopic Surveillance in the Detection of Local Recurrence After Radical Rectal Cancer Surgery is Limited: A Retrospective Study.
Authors: Jankowski Michal , Wysocki Wojciech M. , Tkaczyński Karol , Wiśniewski Dorian , Las-Jankowska Manuela , Bała Dariusz , Zegarski Wojciech 
Published: February 2021

Abstract
Background: Rectal cancer, one of most common neoplasms, is characterized by an overall survival rate exceeding 60%. Nonetheless, local recurrence (LR) following surgery for rectal cancer remains a formidable clinical problem. The aim of this study was to assess the value of postoperative endoscopic surveillance (PES) for the early detection of LR in rectal cancer after radical treatment.Methods: We performed an anterior resection in 228 patients with stage I-III rectal cancer who had undergone surgery from 2001 to 2008 in the Oncology Center in Bydgoszcz, Poland. Of these patients, 169 had perioperative radiotherapy or radiochemotherapy. All patients underwent PES with imaging (abdominal ultrasound or computed tomography scan, pelvic magnetic resonance imaging) and endoscopic examinations. The ratios of sensitivity, specificity, positive likelihood ratio, negative likelihood ratio, and receiver operating characteristic curve were calculated to compare the diagnostic value of colonoscopy versus imaging techniques. Results: During the 5-year follow-up, recurrences occurred in 49 (21%) patients; of these, 15 (6%) had LR, which was most often located outside the intestinal lumen (n = 10, 4%). Anastomotic LR occurred in 5 (2%) patients. The mean time to anastomotic LR was 30 months after initial surgery, similar to that of other locations (29 months). Both imaging and endoscopy were shown to be efficient techniques for the diagnosis of LR in anastomotic sites, and endoscopy did not provide any additional benefit in patients who were receiving radiation therapy.Conclusions: The benefit of PES for the detection of LR after curative treatment of rectal cancer is limited. It remains a useful method, however, for the histopathological confirmation of suspected or confirmed recurrence.
Decreases in Concentrations and Human Dietary Intakes of Polychlorinated Biphenyls (PCBs) and Polybrominated Diphenyl Ethers (PBDEs) in Korean Seafood Between 2005 and 2017
Authors: Choi Minkyu , Lee In-seok 
Published: February 2021

Abstract
Concentrations of PCBs and PBDEs were measured in 23 seafood species widely consumed by Korean population in 2005–2007, 2010–2011, and 2015–2017. The Σ82PCB and Σ19PBDE concentrations in the seafood samples of 2015–2017 were 0.06–6.69 ng/g wet weight and 0.01–1.60 ng/g wet weight, respectively. The Σ82PCB and Σ19PBDE concentrations in the samples were correlated significantly, and elevated PCB and PBDE concentrations were found in fatty fish such as herring, mackerel, and tuna. The current intakes of PCBs and PBDEs were much lower than a TDI or a LOAEL. The levels and human dietary intakes of PCBs and PBDEs in the 2015–2017 survey showed decreases of 17–73% and 57–86%, respectively, in relation to the 2005–2007 and 2010–2011 surveys. This indicates that global bans on PCBs and PBDEs have been effective, and their levels and exposure have been gradually declining.
Improved Mood Boosts Memory Training Gains in Older Adults With Subjective Memory Complaints: A Randomized Controlled Trial
Authors: Yin Shufei , Zhu Xinyi , Li Rui , Huo Lijuan , Ren Weicong , Xiao Qiaoling , Lang Minjia , Li Jin , Hou Jianhua , Niu Yanan , Li Juan 
Published: February 2021

Abstract
Objective: Older adults with subjective memory complaints (SMC) have a higher risk of dementia and commonly demonstrate symptoms of depression and anxiety. The study aimed to examine the effect of a memory training program for individuals with SMC, and whether memory training combined with group counseling aimed at alleviating depression and anxiety would boost memory training gains.Design: A three-armed, double-blind, randomized controlled trial.Setting and Participants: Community-dwelling older adults with SMC, aged ≥ 60 years.Methods: Participants (n = 124) were randomly assigned to memory training (MT), group counseling (GC), or GC+MT intervention. The GT+MT group received 4-hour group counseling followed by a 4-week memory training, while the MT group attended reading and memory training, and the GC group received group counseling and health lectures. Cognitive function and symptoms of depression and anxiety were assessed at baseline, mid-, and post-intervention. The GC+MT group and GC group had resting-state functional magnetic resonance imaging at mid- and post-intervention.Results: After group counseling, the GC+MT and GC groups showed reduced symptoms of anxiety and depression, compared to the MT group. Memory training enhanced memory performance in both MT and GC+MT groups, but the GC+MT group demonstrated larger memory improvement (Cohen’s d = 0.96) than the MT group (Cohen’s d = 0.62). Amygdala-hippocampus connectivity was associated with improved mood and memory gains.Conclusion and Implications: Group counseling reduced symptoms of anxiety and depression, and memory training enhanced memory performance. Specifically, improved mood induced larger memory training effects. The results suggest that it may need to include treatment for depression and anxiety in memory intervention for older adults with SMC.Trial Registration: ChiCTR-IOR-15006165 in the Chinese Clinical Trial Registry.
Active Treatment Strategy Improves Overall Survival of Patients With Intracranial Mesenchymal Chondrosarcoma After Surgical Treatment
Authors: Chen Junyu , Chen Bo , Hu Fei , Qiu Yong , Xiao Guomin , Zhou Junge , Zhang Fangcheng 
Published: February 2021

Abstract
Intracranial mesenchymal chondrosarcoma (IMC) is a rare malignancy. We aimed to investigate the efficacy of treatment in overall survival (OS) for patients with IMC. Firstly, we retrospectively collected 9 cases from two medical centers, then screened the publications and enrolled 112 reported cases, and finally pooled these data together to analyze candidate prognostic factors for OS. For the treatment-related predictors, we defined active intervention if GTR (gross total resection) and/or radiotherapy (GaoR) was employed and inactive one when neither GTR nor radiotherapy (NGnR) was used. The 1-year, 3-year and 5-year OS for patients with IMC were 82.6%, 60.3% and 49.4%, respectively. NGnR was the independent risk factor for OS (HR [hazard ratio] = 4.70, 95% CI [confidence interval] 1.575 ~ 14.060; p = 0.006). The 1-year, 3-year and 5-year of patients with GaoR were higher than that of patients with NGnR (85.1%, 68.7% and 57.7% vs. 72.7%, 42.4% and 21.2%). Patients with IMC could obtain survival benefit from active intervention (GaoR group). GTR and/or radiotherapy should be recommended whenever feasible.