bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of resting metabolic rate prediction equations in college-aged adults
Authors: Ducharme Jeremy B. , Fennel Zachary J. , Pike Ben , Coleman Alexis , Mermier Christine M. , Lauver Jakob D. , Guilkey Justin P. , Johnson Kelly E. 
Published: January 2021

Prediction equations have been considered an accurate method for estimating resting metabolic rate (RMR) across multiple populations, but their accuracy for college-aged individuals not on an athletics team remains to be determined. Sixty-two college-aged (18–30 yrs) males (n = 31) and females (n = 31) had their RMR measured (RMRm), using indirect calorimetry, and body composition assessed via air-displacement plethysmography. The World Health Organization (WHO), Mifflin−St Jeor (Mifflin), Harris−Benedict (HB), Cunningham, and Nelson equations were used to estimate RMR. No difference was observed between the Cunningham and RMRm regardless of sex (p ≥ 0.05). All other prediction equations estimated a significantly lower RMR for males (p < 0.05). The Mifflin and Nelson equations predicted an RMR that was significantly lower than RMRm for females (p < 0.05). When compared with RMRm, no difference was detected for females using the WHO, HB, or Cunningham (p ≥ 0.05). Only the Nelson equation predicted an RMR that was outside of the clinically acceptable range (±10% of RMRm) regardless of sex. The Cunningham, WHO, and HB equations can accurately predict RMR for college-aged males and females. RMR prediction equations used in this study are less accurate for those with greater RMRs. Novelty: For adults 18–30 years old that are not on an athletics team, the Cunningham equation can accurately predict RMR. The Nelson equation should not be used to predict RMR for this population. There is a systematic bias for RMR prediction equations to underestimate higher measured RMR values.
Predicting open-water thermal regimes of temperate North American lakes
Authors: Gillis Daniel P. , Minns Charles K. , Shuter Brian J. 
Published: January 2021

Temperature profoundly affects the physical, chemical, and biological attributes of lakes and is influenced by several abiotic factors. Lake temperature modelling permits regional estimates of seasonal fish thermal habitat availability; however, this requires models that are accurate across large spatial scales. To address this, we fit a semi-mechanistic seasonal temperature-profile model (STM) to 369 morphometrically diverse North American lakes with data spanning 1971–2016. STM with a fixed-depth thermocline formula accurately modelled lake temperature (median pseudo-R2: 0.95, median lake-year-specific root mean square error (RMSE): 1.13 °C). We used random forests to select candidate predictors, then used linear mixed-effects modelling, based on these predictors, to create empirical equations to predict STM parameters from lake-specific morphometric and climate measures. We tested the accuracy of our equations by predicting thermal profiles in 776 Ontario lakes, finding good agreement between predicted and observed temperatures (median lake-year-specific RMSE: 2.38 °C) and stratification occurrence (91.7%). These findings enhance our understanding of the factors that influence lake temperatures and can be used to identify lake types and regions that may be especially susceptible to climate change.
Impact of LHC Higgs couplings measurements on bosonic decays of the neutral Higgs sector in the scNMSSM
Authors: Telba Marwa , Binjonaid Maien 
Published: January 2021

We analyze the Next-to-minimal supersymmetric Standard Model with Grand unification boundary conditions under current theoretical and experimental constraints. We compute the mass spectrum of the model and focus on the three lightest particles in the Higgs sector (two CP-even scalars, [Formula: see text], [Formula: see text] and one CP-odd, [Formula: see text]). The reduced couplings of such particles, singlet-doublet components, their branching ratios to bosons and reduced cross-section to photons and massive gauge bosons via gluon fusion are thoroughly and systematically scrutinized. Our analysis is focused on the parameter space where the singlet-doublet coupling [Formula: see text] is as large as possible (keeping the perturbativity bound intact) and the ratio between the vacuum expectation values of the up-type and down-type Higgses [Formula: see text] is as small as possible, which is the region representing the most natural case of the NMSSM. We show the impact of recent constraints from the LHC on the SM-Higgs couplings to bosons and fermions on the parameter space of the model and the consequent implications on the Higgs sector. The results show that while the model is still able to account for current data, and provide an opportunity for discovery of extended Higgs sectors, recent LHC Higgs couplings constraints rule-out parts of the parameter space where [Formula: see text] (non-SM-like) and [Formula: see text] are non-singlet with masses below 400 GeV.
Impact of Preexisting Cognitive Impairment and Race/Ethnicity on Functional Outcomes Following Intracerebral Hemorrhage
Authors: Sawyer Russell P. , Yim Eunji , Coleman Elisheva , Demel Stacie L. , Sekar Padmini , Woo Daniel 
Published: January 2021

Background and Purpose:
In intracerebral hemorrhage (ICH), preexisting cognitive impairment has been identified as a risk factor for increased mortality and morbidity. However, previous studies examined predominantly White populations; therefore, the prevalence and effect of preICH cognitive impairment has not been studied in a multiethnic cohort. This limits the generalizability of previous findings. We sought to investigate the role of preexisting cognitive impairment in a multiethnic population on short-term mortality and functional outcomes after ICH.

Methods:
Patients with ICH were prospectively enrolled as cases for the GERFHS III (Genetic and Environmental Risk Factors for Hemorrhagic Stroke) Study and the Ethnic/Racial Variations of ICH (ERICH) Study. Cognitive impairment before ICH was defined as positive history of dementia or treatment with donepezil, galantamine, memantine, or rivastigmine on chart abstraction or baseline interview. Specific outcomes—modified Rankin Scale score at 3 months (0–2 versus ≥3), Barthel Index score (<100 versus 100) at 3 months, and withdrawal of care—were analyzed using multivariable logistic regression. Propensity score matching and analysis was done because of imbalances between cognitively impaired and cognitively intact groups.

Results:
Of the 3537 cases of ICH, 304 patients had cognitive impairment predating ICH. Cognitively impaired subjects were more likely to experience withdrawal of care during hospitalization, and for survivors, greater disability (modified Rankin Scale score of ≥3) and lower Barthel scores after ICH. After propensity score matching, preexisting cognitive impairment was associated with a lower modified Rankin Scale at 3 months in the White, Black, and Hispanic subgroups.

Conclusions:
Preexisting cognitive impairment was associated with loss of independence 3-month post-ICH, when matching for risk factors of cognitive impairment, in the White, Black, and Hispanic subgroups. This suggests that preexisting cognitive impairment has a negative effect in obtaining functional independence following ICH, irrespective of race/ethnicity.
Biblical Seductresses
Authors: Weiss Shira 
Published: January 2021

Abstract
Within the texts of the Bible, there are seductresses who are portrayed as resisting the patriarchal values of biblical society by employing their feminine wiles to manipulate powerful males. These women sacrifice their own virtue by taking initiative in sexually daring acts and subordinating their victim of seduction to further their pursuits. Numerous female biblical figures are praised after utilizing their feminine weapons to achieve their ends; however, these seducers, some of whom are married, engage in questionable means. Since the Bible does not render an explicit evaluation, I aim to investigate such seductive behavior in an effort to assess the conduct of biblical seductresses and illuminate the role of women depicted in the Bible. A close reading of the texts and an examination of rabbinic interpretations of episodes in which Lot’s daughters, Tamar, Jael, Ruth and Esther each perform seductive acts can be used as a resource to further support contemporary feminist readings which justify biblical female characters’ use of morally dubious means to accomplish noble aims.
Seasonal Evolution of Anomalous Rainband over East China Regulated by Sea Surface Temperature Anomalies in the Northern Hemisphere
Authors: Liu Boqi , Zhu Congwen , Jiang Ning , Guo Li 
Published: January 2021

AbstractSeasonal evolution of rainband over East China is evident and shows remarkable year-to-year variations. The present study identified two dominant interannual modes of the seasonal evolution of rainband over East China from 1981 to 2018: (1) the sudden change pattern, in which the anomalous rainfall changes abruptly from boreal spring to summer, especially over South China; and (2) the northward migration pattern, which shows a gradual poleward migration of the anomalous rainband over East China with the East Asian summer monsoon (EASM). Both of them are regulated by the sea surface temperature anomalies (SSTAs) in the Northern Hemisphere from spring to summer. In the sudden change pattern, the SSTAs in the Pacific modulate spring rainfall over South China via the ENSO–EASM teleconnection. By contrast, the North Atlantic SSTAs change the mid-latitude wave train and modify summer rainfall over South and North China, in conjunction with the anomalous tropical circulation due to the Indian SSTAs. In the northward migration pattern, the North Pacific SSTAs alter spring rainfall over South China by varying the low-level western North Pacific subtropical high and the zonal land–sea thermal contrast over East Asia. Afterward, the ENSO-like SSTAs induce a Pacific–Japan teleconnection and shift the anomalous rainband northward to the Yangtze-Huai River and North China in summer. The seasonal switch of the SSTAs regulating these two modes is physically linked from boreal spring to summer. This mechanism provides potential seasonal predictability of the seasonal evolution of the anomalous rainband over East China.
The Cyclonic Mode of Arctic Ocean Circulation
Authors: Morison James , Kwok Ron , Dickinson Suzanne , Andersen Roger , Peralta-Ferriz Cecilia , Morison David , Rigor Ignatius , Dewey Sarah , Guthrie John 
Published: January 2021

AbstractArctic Ocean surface circulation change should not be viewed as the strength of the anticyclonic Beaufort Gyre. While the Beaufort Gyre is a dominant feature of average Arctic Ocean surface circulation, empirical orthogonal function analysis of dynamic height (1950–89) and satellite altimetry–derived dynamic ocean topography (2004–19) show the primary pattern of variability in its cyclonic mode is dominated by a depression of the sea surface and cyclonic surface circulation on the Russian side of the Arctic Ocean. Changes in surface circulation after Arctic Oscillation (AO) maxima in 1989 and 2007–08 and after an AO minimum in 2010 indicate the cyclonic mode is forced by the AO with a lag of about 1 year. Associated with a one standard deviation increase in the average AO starting in the early 1990s, Arctic Ocean surface circulation underwent a cyclonic shift evidenced by increased spatial-average vorticity. Under increased AO, the cyclonic mode complex also includes increased export of sea ice and near-surface freshwater, a changed path of Eurasian runoff, a freshened Beaufort Sea, and weakened cold halocline layer that insulates sea ice from Atlantic water heat, an impact compounded by increased Atlantic Water inflow and cyclonic circulation at depth. The cyclonic mode’s connection with the AO is important because the AO is a major global scale climate index predicted to increase with global warming. Given the present bias in concentration of in situ measurements in the Beaufort Gyre and Transpolar Drift, a coordinated effort should be made to better observe the cyclonic mode.
Does Pepsin Saliva Concentration (Peptest™) Predict the Therapeutic Response of Laryngopharyngeal Reflux Patients?
Authors: Lechien Jerome R. , Bobin Francois , Dequanter Didier , Rodriguez Alexandra , Le Bon Serge , Horoi Mihaela , Thill Marie-Paule , Salem Charelle , Muls Vinciane , Saussez Sven 
Published: January 2021

Objective: To study the profile and the therapeutic response of patients with laryngopharyngeal reflux (LPR) at the hypopharyngeal-esophageal multichannel intraluminal impedance-pH monitoring (HEMII-pH) according to the initial pepsin saliva concentration. Methods: From January 2018 to January 2020, patients with positive LPR diagnosis at the HEMII-pH were consecutively recruited from 3 European Hospitals. Saliva pepsin concentration (Peptest™) was measured during the HEMII-pH testing period and patients were classified into 2 groups: negative versus positive Peptest. The clinical outcomes, that is, gastrointestinal and HEMII-pH findings, reflux symptom score-12 (RSS-12), and 3-month therapeutic response, were compared between groups. Results: A total of 124 patients completed the study. Among them, 30 patients had negative Peptest. Pharyngeal reflux events occurred outside 1-hour post-meal time in 74.0%, after the meals in 20.5% and nighttime in 5.5%. The pepsin saliva level was not significantly associated with the reflux events preceding the sample collection. Patients with positive Peptest had better improvement of RSS-12 digestive and respiratory subscores and oral, pharyngeal, and laryngeal findings compared with patients with negative Peptest. Conclusion: Patients with high saliva pepsin concentration had no stronger gastrointestinal, HEMII-pH, or clinical outcomes compared with those with low or undetectable saliva pepsin concentration.
Worlding geography: From linguistic privilege to decolonial anywheres
Authors: Müller Martin 
Published: January 2021

Geography studies the world. Our knowledge of the world, however, comes mostly from Anglophone sources. This makes Geography in urgent need of worlding – of including multiple voices and languages from around the world. Introducing the notion of linguistic privilege, the article establishes language as an important dimension of epistemic struggle, alongside gender, race, class and others. Its analysis finds the greatest linguistic privilege in the most influential positions in knowledge production – editors of handbooks and journals and authors of progress reports. Three strategies of worlding should challenge this: making gatekeepers multilingual, promoting multiple Englishes and valorising ex-centric knowledge.
Ultrasound characterization of the nail bed in patients with systemic lupus erythematosus
Authors: Ferrusquia-Toriz Diana , Hernández-Díaz Cristina , Amezcua-Guerra Luis M , Ventura-Ríos Lucio , Higuera-Ortiz Violeta , Lozada-Navarro Ana C , Silveira Luis H 
Published: January 2021

Objective To characterize the ultrasound findings of the nail plate and nail bed in systemic lupus erythematosus (SLE) and its association with nail dystrophy. Methods Thirty-two SLE patients, 36 patients with osteoarthritis (OA) and 20 healthy individuals were studied. High-frequency linear ultrasound was performed in nails of the second to fifth fingers in all participants. Disease activity (SLEDAI-2K index), accrued organ damage (SLICC/ACR index), autoantibody profile, and Raynaud’s phenomenon were also assessed in SLE patients. Results Nail bed thickness in SLE patients was higher than in healthy individuals (1.25 ± 0.31 mm vs 1.17 ± 0.29 mm; P = 0.01) but lower than in OA (1.39 ± 0.37 mm; P < 0.001), while nail plate thickness was similar among groups. Nail dystrophy was found more frequently in SLE and OA than in healthy individuals. SLE patients with nail dystrophy were older than their counterparts with no dystrophy (39.4 ± 10.4 years vs 27.8 ± 5.6 years; P = 0.004), although nail dystrophy showed no association with SLICC/ACR, SLEDAI-2K, nail bed vascularity, or autoantibodies. Conclusions Nail bed in SLE patients is thicker than in healthy individuals but thinner than in OA patients. Nail dystrophy in SLE is associated with advanced age, but not with accrued organ damage, disease activity, Raynaud's phenomenon, or DIP synovitis assessed by ultrasound.
Pseudobulbar Affect Symptoms in Nursing Home Patients with Neurocognitive Disorders
Authors: de Similien Ralph , Al-Jammaly Milania D , Predescu Iuliana , Belzie Louis 
Published: January 2021

Background: Symptoms of pseudobulbar affect (PBA) often are misinterpreted as those of a mood disorder. Symptoms seen in patients with PBA can be influenced by a mood disorder and vice versa. Our aim in this study was to determine the occurrence rate of PBA symptoms and comorbid depressive symptoms in a cohort of nursing home patients with different subtypes of neurocognitive disorders (NCD)/dementia. Methods: Eighty patients were screened and 61 met the inclusion criteria. These individuals were divided into 5 groups according to NCD subtypes: Alzheimer’s disease, vascular, HIV, unspecified, or combined types. The Center for Neurologic Study–Lability Scale (CNS-LS) and the Geriatric Depression Scale–Short Form (GDS-SF) were used to screen for PBA and depressive symptoms, respectively. The Mini-Mental Status Exam (MMSE) was used to determine patients’ baseline functioning. Fifty-nine patients successfully completed the CNS-LS and 42 completed the GDS. Results: Forty-four percent of individuals screened positive for PBA symptoms. Depressive symptoms were found among 23% of these patients. Not only were PBA-symptoms positive patients common among this nursing home residents, the PBA-symptoms positive patients were found to cluster mostly among those with NCD due to HIV (66.0%). PBA symptom-positive patients often received psychotropics. Conclusion: Better awareness, screening tools, and treatment approaches for patients with NCD expressing PBA-symptoms—especially those with NCD due to HIV Infection—are needed.
Impact of Patient Load on the Quality of Electronic Medical Record Documentation
Authors: Jacob Aasems , Raj Rishi , Alagusundaramoorthy Sayee , Wei Jing , Wu Jianrong , Eng Margaret 
Published: January 2021

Objective: American College of Graduate Medical Education (ACGME) recommends ongoing care of 10 patients per resident however its implication is unclear. We hypothesized EMR quality to vary based on patient load and call status. Methods: We conducted a double-blind, single-center, retrospective observational study between 2017 and 2019 to investigate the quality and accuracy of resident documentation using the Responsible Electronic Documentation (RED) Checklist, a validated scoring system. Results: A total of 234 independent charts were analyzed and 80 met scoring criteria. Average patients per residents was 4, 9.1, 7.2, and 5.5 on “call” day (D0), “post-call” day (D1), “mid-call” day (D2), and “pre-call” day (D3), respectively. Mean RED checklist scores were 68.1%, 57%, 68.6%, and 72.1% on the above call status. The difference in score between D3 and D1 was statistically significant ( P = .00042). There was a negative correlation between score and number of patients per resident ( r = −0.286, P = .010). Conclusion: EMR documentation quality is directly impacted by patient load and resident call status with the lowest documentation quality on post-call day, correlating with patient load.
Temperament and character of patients with alcohol toxicity during COVID − 19 pandemic
Authors: Estedlal Ali Reza , Mani Arash , Vardanjani Hossein Molavi , Kamali Mahsa , Zarei Leila , Heydari Seyed Taghi , Lankarani Kamran Bagheri 
Published: January 2021

Abstract
Background
Corona virus epidemic may be acts as a stressor or trauma that affects both physical health and mental health. People exhibited various reactive behaviors to confront with this stressful situation. In Iran, one of the common motives for alcohol consumption is to scape problems and cope with stresses. It has been shown that personality factors influence alcohol consumption, since they are associated with drinking motives. The main purpose of this study was to investigate the correlation between temperament and character and alcohol abuse.

Methods
This cross-section study was conducted on 135 alcohol intoxicated patients admitted to emergency room in March 2020 and 255 participants who were randomly selected from public in Shiraz. A questionnaire consisted of TCI (Temperament and character inventory) and several questions about COVID-19 pandemic. It was completed by a trained interviewer using the matched answer technique. Demographic factors were self-reported.

Results
Among the alcohol intoxicated group, 117 (86.7%) were males and 18(13.3%) were females. The mean age of the participants was 32.43 ± 10.81 years. Among control group, 99 (38.8%) were males and 156 (61.2%) were females. The mean age of control group was 33.12 ± 14.77 years. Alcohol toxicity was mostly observed among the young males (male/female ratio was 6.45). According to temperament and character index, mean scores of novelty seeking, harm avoidant, and self-transcendence were higher in the alcohol toxicity group than normal population (P < 0.01). Mean scores of reward dependent, cooperativeness, and self-directedness were higher in normal population than the alcohol toxicity group (P < 0.001). The mean score of persistence was not significantly different between methanol intoxicated and normal population groups (P = 0.718).

Conclusion
Alcohol intoxicated patients had higher scores of novelty-seeking and self-transcendence and lower scores of reward-dependency scores, cooperativeness and self-directedness. These scores are associated with higher likelihood of personality disorders.
Topical co‐administration of zoledronate with recombinant human bone morphogenetic protein-2 can induce and maintain bone formation in the bone marrow environment
Authors: Ueyama Hideki , Ohta Yoichi , Imai Yuuki , Suzuki Akinobu , Sugama Ryo , Minoda Yukihide , Takaoka Kunio , Nakamura Hiroaki 
Published: January 2021

Abstract
Background
Bone morphogenetic proteins (BMPs) induce osteogenesis in various environments. However, when BMPs are used alone in the bone marrow environment, the maintenance of new bone formation is difficult owing to vigorous bone resorption. This is because BMPs stimulate the differentiation of not only osteoblast precursor cells but also osteoclast precursor cells. The present study aimed to induce and maintain new bone formation using the topical co-administration of recombinant human BMP-2 (rh-BMP-2) and zoledronate (ZOL) on beta-tricalcium phosphate (β-TCP) composite.

Methods
β-TCP columns were impregnated with both rh-BMP-2 (30 µg) and ZOL (5 µg), rh-BMP-2 alone, or ZOL alone, and implanted into the left femur canal of New Zealand white rabbits (n = 56). The implanted β-TCP columns were harvested and evaluated at 3 and 6 weeks after implantation. These harvested β-TCP columns were evaluated radiologically using plane radiograph, and histologically using haematoxylin/eosin (H&E) and Masson’s trichrome (MT) staining. In addition, micro-computed tomography (CT) was performed for qualitative analysis of bone formation in each group (n = 7).

Results
Tissue sections stained with H&E and MT dyes revealed that new bone formation inside the β-TCP composite was significantly greater in those impregnated with both rh-BMP-2 and ZOL than in those from the other experimental groups at 3 and 6 weeks after implantations (p < 0.05). Micro-CT data also demonstrated that the bone volume and the bone mineral density inside the β-TCP columns were significantly greater in those impregnated with both rh-BMP-2 and ZOL than in those from the other experimental groups at 3 and 6 weeks after implantations (p < 0.05).

Conclusions
The topical co-administration of both rh-BMP-2 and ZOL on β-TCP composite promoted and maintained newly formed bone structure in the bone marrow environment.