bluuebunny/crossref_metadata_2025_split huggingface dataset:
Detection of relevant extracardiac findings on coronary computed tomography angiography vs. invasive coronary angiography
Authors: Laskowski Dominik , Feger Sarah , Bosserdt Maria , Zimmermann Elke , Mohamed Mahmoud , Kendziora Benjamin , Rief Matthias , Dreger Henryk , Estrella Melanie , Dewey Marc 
Published: June 2021

Abstract
Objectives
To compare the detection of relevant extracardiac findings (ECFs) on coronary computed tomography angiography (CTA) and invasive coronary angiography (ICA) and evaluate the potential clinical benefit of their detection.

Methods
This is the prespecified subanalysis of ECFs in patients presenting with a clinical indication for ICA based on atypical angina and suspected coronary artery disease (CAD) included in the prospective single-center randomized controlled Coronary Artery Disease Management (CAD-Man) study. ECFs requiring immediate therapy and/or further workup including additional imaging were defined as clinically relevant. We evaluated the scope of ECFs in 329 patients and analyzed the potential clinical benefit of their detection.

Results
ECFs were detected in 107 of 329 patients (32.5%; CTA: 101/167, 60.5%; ICA: 6/162, 3.7%; p < .001). Fifty-nine patients had clinically relevant ECFs (17.9%; CTA: 55/167, 32.9%; ICA: 4/162, 2.5%; p < .001). In the CTA group, ECFs potentially explained atypical chest pain in 13 of 101 patients with ECFs (12.9%). After initiation of therapy, chest pain improved in 4 (4.0%) and resolved in 7 patients (6.9%). Follow-up imaging was recommended in 33 (10.0%; CTA: 30/167, 18.0%; ICA: 3/162, 1.9%) and additional clinic consultation in 26 patients (7.9%; CTA: 25/167, 15.0%; ICA: 1/162, 0.6%). Malignancy was newly diagnosed in one patient (0.3%; CTA: 1/167, 0.6%; ICA: 0).

Conclusions
In this randomized study, CTA but not ICA detected clinically relevant ECFs that may point to possible other causes of chest pain in patients without CAD. Thus, CTA might preclude the need for ICA in those patients.

Trial registration
NCT Unique ID: 00844220

Key Points
• CTA detects ten times more clinically relevant ECFs than ICA.
• Actionable clinically relevant ECFs affect patient management and therapy and may thus improve chest pain.
• Detection of ECFs explaining chest pain on CTA might preclude the need for performing ICA.
Hypovitaminosis D in migrant children in Switzerland: a retrospective study
Authors: Fahrni Olivia , Wilhelm-Bals Alexandra , Posfay-Barbe Klara M. , Wagner Noémie 
Published: June 2021

AbstractCholecalciferol (vitamin D3) is essentially known for its role in the phosphocalcic metabolism and its associated pathologies, such as rickets. In Switzerland, 35 to 50% of children are vitamin D deficient. Due to skin colour, poor nutrition, living conditions and cultural practices, migrant population is particularly at risk. Our aim is to attest the prevalence of hypovitaminosis D in children arriving in Switzerland. We retrospectively assessed 528 children’s vitamin D status and parathyroid hormone, phosphate and calcium levels between 2015 and 2018 by electrochemiluminescence and spectrophotometry. Cholecalciferol was considered insufficient under 50 nmol/L and severely deficient below 25 nmol/L. Seventy-three percent of children showed hypovitaminosis D and 28% had a severe deficiency. Highest prevalence of deficiency was found in children from Eastern Mediterranean (80%) and African regions (75%). Severe deficiency was more prevalent in the South East Asian (39%) and Eastern Mediterranean regions (33%) and more frequent in females. Deficiency was more frequent and more severe in winter. Hypovitaminosis D increased with age. Two children presented with all three biological manifestations associated to severe hypovitaminosis D (hyperparathyroidism, hypocalcaemia and hypophosphatemia).Conclusion: A majority of migrant children presented with hypovitaminosis D. They should be supplemented to prevent complications. A strategy could be to supplement all children at arrival and during wintertime without regular vitamin D level checks.

What is Known:Hypovitaminosis D is frequent in children and can lead to bone-related complications.Migrant children are particularly at risk of deficiency.

What is New:Three-quarters of migrant children evaluated at our migrant clinic in Geneva’s children hospital are deficient in vitamin D, one third severely.A strategy to correct the deficiency would be to supplement all migrant children at arrival and in winter.
On the Ehrhart Polynomial of Minimal Matroids
Authors: Ferroni Luis 
Published: June 2021

AbstractWe provide a formula for the Ehrhart polynomial of the connected matroid of size n and rank k with the least number of bases, also known as a minimal matroid. We prove that their polytopes are Ehrhart positive and $$h^*$$

h
∗

-real-rooted (and hence unimodal). We prove that the operation of circuit-hyperplane relaxation relates minimal matroids and matroid polytopes subdivisions, and also preserves Ehrhart positivity. We state two conjectures: that indeed all matroids are $$h^*$$

h
∗

-real-rooted, and that the coefficients of the Ehrhart polynomial of a connected matroid of fixed rank and cardinality are bounded by those of the corresponding minimal matroid and the corresponding uniform matroid.
Towards human distance estimation using a thermal sensor array
Authors: Naser Abdallah , Lotfi Ahmad , Zhong Joni 
Published: June 2021

AbstractHuman distance estimation is essential in many vital applications, specifically, in human localisation-based systems, such as independent living for older adults applications, and making places safe through preventing the transmission of contagious diseases through social distancing alert systems. Previous approaches to estimate the distance between a reference sensing device and human subject relied on visual or high-resolution thermal cameras. However, regular visual cameras have serious concerns about people’s privacy in indoor environments, and high-resolution thermal cameras are costly. This paper proposes a novel approach to estimate the distance for indoor human-centred applications using a low-resolution thermal sensor array. The proposed system presents a discrete and adaptive sensor placement continuous distance estimators using classification techniques and artificial neural network, respectively. It also proposes a real-time distance-based field of view classification through a novel image-based feature. Besides, the paper proposes a transfer application to the proposed continuous distance estimator to measure human height. The proposed approach is evaluated in different indoor environments, sensor placements with different participants. This paper shows a median overall error of $$\pm 0.2$$

±
0.2

m in continuous-based estimation and $$96.8\%$$

96.8
%

achieved-accuracy in discrete distance estimation.
Two novel bornaviruses identified in colubrid and viperid snakes
Authors: Pfaff Florian , Rubbenstroth Dennis 
Published: June 2021

AbstractWe present the complete genome sequences of Caribbean watersnake bornavirus (CWBV) and Mexican black-tailed rattlesnake bornavirus (MRBV), which we identified in archived raw transcriptomic read data of a Caribbean watersnake (Tretanorhinus variabilis) and a Mexican black-tailed rattlesnake (Crotalus molossus nigrescens), respectively. The genomes of CWBV and MRBV have a length of about 8,900 nucleotides and comprise the complete coding regions and the untranslated regions. The overall genomic makeup and predicted gene content is typical for members of the genus Orthobornavirus within the family Bornaviridae. Alternative splicing was detected for the L and M genes. Based on a phylogenetic analysis of all viral proteins, we consider both viruses to be members of a single novel species within the genus Orthobornavirus. Both viruses form a distinct outgroup to all currently known orthobornaviruses. Based on the novel virus genomes, we furthermore identified closely related endogenous bornavirus-like nucleoprotein sequences in transcriptomic data of veiled chameleons (Chamaeleo calyptratus) and a common lancehead (Bothrops atrox).
High levels of halogenated natural products in large pelagic fish from the Western Indian Ocean
Authors: Wu Qiong , Munschy Catherine , Aminot Yann , Bodin Nathalie , Vetter Walter 
Published: June 2021

AbstractConcentrations, profiles and muscle-liver distribution of halogenated natural products (HNPs) and anthropogenic persistent organic pollutants (POPs) were investigated in five large pelagic fish species and one smaller planktivore fish species from the Western Indian Ocean. Analysis of swordfish muscle from the Seychelles revealed the predominance of HNPs, with the highest concentrations found for 2′-methoxy-2,3′,4,5′- tetraBDE (2′-MeO-BDE 68 or BC-2), 6-methoxy-2,2′,4,4′- tetraBDE (6-MeO-BDE 47 or BC-3) and 2,3,3′,4,4′,5,5′-heptachloro-1′-methyl-1,2′-bipyrrole (Q1), along with varied contributions of further HNPs. The mean concentration of ∑HNPs (330 ng/g lw) was one or two orders of magnitude higher than ∑DDTs (60 ng/g lw) and ∑PCBs (6.8 ng/g lw). HNPs (BC-2, BC-3 and Q1) were also predominant in individual samples of three tropical tuna species from the Seychelles and from other regions of the Western Indian Ocean (Mozambique Channel, off Somalia and Chagos Archipelago). Non-targeted gas chromatography coupled with electron capture negative ion mass spectrometry operated in the selected ion monitoring mode (GC/ECNI-MS-SIM) analysis of one swordfish sample indicated low abundance of rarely reported HNPs (three hexachloro-1′-methyl-1,2′-bipyrrole (Cl6-MBP) isomers and pentabromo-1,1′-dimethyl-2,2′-bipyrroles (Br5-DBP)) but no further abundant unscreened polyhalogenated compounds.
Initiating scientific collaborations across career levels and disciplines – a network analysis on behavioral data
Authors: Eberle Julia , Stegmann Karsten , Barrat Alain , Fischer Frank , Lund Kristine 
Published: June 2021

AbstractCollaborations are essential in research, especially in answering increasingly complex questions that require integrating knowledge from different disciplines and that engage multiple stakeholders. Fostering such collaboration between newcomers and established researchers helps keep scientific communities alive while opening the way to innovation. But this is a challenge for scientific communities, especially as little is known about the onset of such collaborations. Prior social network research suggests that face-to-face interaction at scientific events as well as both network-driven selection patterns (reciprocity and transitivity) and patterns of active selection of specific others (homophily / heterophily) may be important. Learning science research implies, moreover, that selecting appropriate collaboration partners may require group awareness. In a field study at two scientific events on technology-enhanced learning (Alpine Rendez-Vous 2011 and 2013) including N = 5736 relations between 287 researchers, we investigated how researchers selected future collaboration partners, looking specifically at the role of career level, disciplinary background, and selection patterns. Face-to-face contact was measured using RFID devices. Additionally, a group awareness intervention was experimentally varied. Data was analyzed using RSiena and meta-analyses. The results showed that transitivity, reciprocity and contact duration are relevant for the identification of new potential collaboration partners. PhD students were less often chosen as new potential collaboration partners, and researchers with a background in Information Technology selected fewer new potential collaboration partners. However, group awareness support balanced this disciplinary difference. Theoretical, methodological, and practical implications of these findings are discussed.
A new framework to determine general multimodal soil water characteristic curves
Authors: Yan Wei , Birle Emanuel , Cudmani Roberto 
Published: June 2021

AbstractA soil water characteristic curve (SWCC) model named as discrete-continuous multimodal van Genuchten model with a convenient parameter calibration method is developed to describe the relationship between soil suction and the water content of a soil with complex pore structure. The modality number N of the SWCC in the proposed model can be any positive integer (the so-called multimodal or N-modal SWCC). A unique set of parameters is determined by combining curve fitting and a graphical method based on the shape features of the SWCC in the log s–log Se plane. In addition, a modality number reduction method is proposed to minimize the number of parameters and simplify the form of SWCC function. The proposed model is validated using a set of bimodal and trimodal SWCC measurements from different soils, which yield a strong consistency between the fitted curves and the measured SWCC data. The uniqueness in the set of parameters provides the possibility to further improve the proposed model by correlating the parameters to soil properties and state parameters.
Comparative 3D DEM simulations of sand–structure interfaces with similarly shaped clumps versus spheres with contact moments
Authors: Grabowski A. , Nitka M. , Tejchman J. 
Published: June 2021

AbstractThree-dimensional simulations of a monotonic quasi-static interface behaviour between initially dense cohesionless sand and a rigid wall of different roughness during tests in a parallelly guided direct shear test under constant normal stress are presented. Numerical modelling was carried out by the discrete element method (DEM) using clumps in the form of convex non-symmetric irregularly shaped grains. The clumps had an aspect ratio of 1.5. A regular grid of triangular grooves (asperities) along the wall with a different height at the same distance was assumed. The numerical results with clumps were directly compared under the same conditions with our earlier DEM simulations using pure spheres with contact moments with respect to the peak and residual interface friction angle, width of the interface shear zone, ratio between grain slips and grain rotations, distribution of contact forces and stresses. The difference between the behaviour of clumps and pure spheres with contact moments proved to be noticeable in the post-peak regime due to a different particle shape. The rolling resistance model with pure spheres was proved to be limited for capturing particle shape effects. Three different boundary conditions along the interface were proposed for micropolar continua, considering grain rotations and grain slips, wall grain moments and wall grain forces, and normalized interface roughness. The numerical results in this paper offer a better understanding of the interface behaviour of granular bodies in DEM and FEM simulations.
Interventions to Optimise Mental Health Outcomes During the COVID-19 Pandemic: A Scoping Review
Authors: Safieh Jacqueline , Broughan John , McCombe Geoff , McCarthy Niamh , Frawley Timothy , Guerandel Allys , Lambert John S. , Cullen Walter 
Published: June 2021

AbstractAdverse mental health has been a major consequence of the COVID-19 pandemic. This review examines interventions to enhance mental health outcomes and well-being of populations during COVID-19. Four electronic databases (MEDLINE, PsycINFO, Embase, and CINAHL) were searched following Arskey and O’Malley’s six-staged scoping review process. Twenty studies were included in the review. Various study populations were included to ensure greater generalisability of results. Interventions informing treatment of mental health concerns during COVID-19 were included and classified into (a) prevention of poor mental health, (b) therapeutic interventions, and (c) other interventions. Preventative strategies (n = 16) included public health education, modified social media use, technology-based interventions, physical activity, policy adaptations, and therapeutic interventions. Treatment strategies (n = 7) included adapting existing treatment and the creation new treatment programmes and platforms. While current evidence is promising, future research should focus on novel effective interventions to address mental health issues during the pandemic.
Model-based two-way clustering of second-level units in ordinal multilevel latent Markov models
Authors: Montanari Giorgio Eduardo , Doretti Marco , Marino Maria Francesca 
Published: June 2021

AbstractIn this paper, an ordinal multilevel latent Markov model based on separate random effects is proposed. In detail, two distinct second-level discrete effects are considered in the model, one affecting the initial probability vector and the other affecting the transition probability matrix of the first-level ordinal latent Markov process. To model these separate effects, we consider a bi-dimensional mixture specification that allows to avoid unverifiable assumptions on the random effect distribution and to derive a two-way clustering of second-level units. Starting from a general model where the two random effects are dependent, we also obtain the independence model as a special case. The proposal is applied to data on the physical health status of a sample of elderly residents grouped into nursing homes. A simulation study assessing the performance of the proposal is also included.
Hydrocarbon reservoir delineation using simultaneous and elastic impedance inversions in a Niger Delta field
Authors: Adesanya Oluwakemi Y. , Adeoti Lukumon , Oyedele Kayode F. , Afinotan Itsemode P. , Oyeniran Taiwo , Alli Saheed 
Published: June 2021

AbstractThe global energy demand is increasing while production from mature fields is drastically reducing consequently, oil and gas industries are expanding activities into more challenging areas. The inability of the traditional seismic data to properly delineate hydrocarbon reservoirs from subtle seismic features in ‘Sandfish’ field located offshore, Niger Delta informed the use of simultaneous and elastic impedance inversion. The elastic and derived volumes from seismic inversion would reduce risk, enhance hydrocarbon discovery and optimize development plans in the study area. Four ‘Sandfish’ (Sfn) wells (Sfn-01, Sfn-02, Sfn-04 and Sfn-05), check-shots and 3D seismic data of five angle stacks (6–12°, 12–18°, 18–26°, 26–32° and 32–42°) were used in the study. Low frequency (0–2 Hz) models were generated from interpolation of high-cut-filtered compressional wave velocity log (P-sonic), shear wave velocity log (S-sonic) and density log guided by interpreted four seismic horizons. The low frequency models broaden the spectrum of the elastic volumes and also served as inversion constraints. The five partial angle stacks varying from 6–42° were simultaneously inverted using Jason’s Rock-Trace® inversion software which iterated trial inversions until the model sufficiently matched the seismic data. The near (6–12°) angle and far-far (32–42°) angle stacks were also inverted and compared with the inverted volumes from the simultaneous inversion. This was carried out to determine the effectiveness of near and far-far elastic impedance volume in delineating hydrocarbon reservoirs. The inverted elastic volumes P-impedance (ZP), S-impedance (ZS), density (ρ), near and far-far elastic and derived volumes lambda-rho (λρ), mu-rho (µρ), Poisson’s-ratio (σ) reveal vertical and lateral continuity of the reservoirs identified (K01, N01 and P01) at 2179 m, 2484 m and 3048 m, respectively. The delineated reservoirs showed good match with the sand tops away from the well control validated by a blind well test. The cross-plot of inverted ZPfrom simultaneous inversion and well ZPgave correlation coefficient of 86% indicative of high quality inverted volume which will reduce exploration risk. The plot of inverted ZPfrom simultaneous inversion and inverted far-far elastic volume reflected 82% correlation coefficient indicating that this method could be adopted in other fields with limited data and similar geological setting. Hence, the study has shown the efficacy of elastic volumes in delineating hydrocarbon reservoirs which can help locate optimum region for development wells.
Effects of coworker's idiosyncratic deals on witness's creative process engagement: roles of responsibility for change and perceived exploitative leadership
Authors: Huang Jie , Tang Chunyong 
Published: June 2021

AbstractEmerging research in the idiosyncratic deals literature is to examine its negative effects. Thus far, much remains unknown about how and when idiosyncratic deals are associated with employee creative process engagement. Invoking fairness heuristic theory and trait activation theory, we propose and test a model that coworker's idiosyncratic deals have a negative association with witness's creative process engagement through psychological contract violation. Furthermore, we theorize and test the combination of the responsibility for change and perceived exploitative leadership as important boundary conditions, associate interact with coworker's idiosyncratic deals to strengthen the positive impact on psychological contract violation, thereby reducing witness's creative process engagement. We use two time-lagged studies to provide support for these mediation and moderation effects, and also discuss the theoretical and practical implications of these findings.
Securitizing Borders: The Case of South Tyrol
Authors: Carlà Andrea 
Published: June 2021

AbstractSituated at the interplay between ethnic politics, migration, border, and security studies, this contribution analyzes processes of securitization of borders in South Tyrol, an Italian province bordering Austria and Switzerland with a German- and Ladin-speaking population and a past of ethnic tensions. South Tyrol is considered a model for fostering peaceful interethnic relations thanks to a complex power-sharing system. However, the arrival of migrants from foreign countries and the more recent influx of asylum seekers have revitalized debates around the borders between South Tyrol/Italy and Austria and among South Tyrolean linguistic groups. The current COVID-19 pandemic has brought further complexity to the issue. I use the concept of securitization—the process through which an issue is considered as an existential threat requiring exceptional measures—in order to understand why and how borders become exclusionary and restrictive, shaping dynamics of othering. With this framework, the article explores how South Tyrolean borders have been subjected to (de)securitizing and resecuritizing moves in discourses and practices. In this way, I shed new light on debates on the articulation of borders and interethnic relations that are occurring due to recent international migration, consolidation of nationalist agendas, and the current pandemic.
Navigating Ethnicity: Collective Identities and Movement Framing in Deeply Divided Societies
Authors: Milan Chiara 
Published: June 2021

AbstractThis article explores collective identity frames and discursive strategies employed by social movement actors mobilizing in ethnically divided societies, a context where ethnicity constitutes the primary collective category of identification. By using Bosnia and Herzegovina as a case study, it analyzes movement framing in three waves of social protests that occurred in the country in the last decade. Specifically, it investigates the diverse ways in which movement leaders tackled ethnicity in their discourses. The article shows that movement leaders’ narratives rested, respectively, on the primacy of human and citizenship rights, a common feeling of deprivation, and victimhood. Their approach toward ethnicity, however, differed in each wave. Ethnicity was openly rejected in 2013, avoided and not openly contested in 2014, and accepted and approached as an opportunity to bring further support to the movement in 2018. The article highlights that ethnicity can be tackled differently by social movement actors mobilizing on nonethnic grounds in divided societies, and that it might constitute a vantage point for social mobilization rather than a drawback, contributing to raising transversal solidarity.