bluuebunny/crossref_metadata_2025_split huggingface dataset:
The cardboard box study: understanding collaborative data management in the connected home
Authors: Kilic Damla , Crabtree Andy , McGarry Glenn , Goulden Murray 
Published: October 2021

AbstractThe home is a site marked by the increasing collection and use of personal data, whether online or from connected devices. This trend is accompanied by new data protection regulation and the development of privacy enhancing technologies (PETs) that seek to enable individual control over the processing of personal data. However, a great deal of the data generated within the connected home is interpersonal in nature and cannot therefore be attributed to an individual. The cardboard box study adapts the technology probe approach to explore with potential end users the salience of a PET called the Databox and to understand the challenge of collaborative rather than individual data management in the home. The cardboard box study was designed as an ideation card game and conducted with 22 households distributed around the UK, providing us with 38 participants. Demographically, our participants were of varying ages and had a variety of occupational backgrounds and differing household situations. The study makes it perspicuous that privacy is not a ubiquitous concern within the home as a great deal of data is shared by default of people living together; that when privacy is occasioned it performs a distinct social function that is concerned with human security and the safety and integrity of people rather than devices and data; and that current ‘interdependent privacy’ solutions that seek to support collaborative data management are not well aligned with the ways access control is negotiated and managed within the home.
Where has the rum gone? The impact of maritime piracy on trade and transport
Authors: Sandkamp Alexander , Stamer Vincent , Yang Shuyao 
Published: October 2021

AbstractDespite a general agreement that piracy poses a significant threat to maritime shipping, empirical evidence regarding its economic consequences remains scarce. This paper combines firm-level Chinese customs data and ship position data with information on pirate attacks to investigate how exporting firms and cargo ships respond to maritime piracy. It finds that overall exports along affected shipping routes fall following an increase in pirate activity. In addition, piracy induces firms to switch from ocean to air shipping, while remaining ocean shipments become larger. At the ship-level, the paper provides evidence for re-routing, as container ships avoid regions prone to pirate attacks.
Inferior vena cava thrombosis—rope ladder sign
Authors: Meyer Sascha , Poryo Martin 
Published: October 2021

SummaryCongenital heart disease comprises one of the largest groups of congenital defects, affecting approximately 1% of births. Advances in pre- and postoperative critical care treatment as well as surgery and interventional procedures have improved survival rates, but treatment and long-term care of children with complex congenital heart disease remains challenging, and is associated with a number of complications.Here, we report on a 17-month-old infant with congenital univentricular heart disease who devloped post-operatively inferior vena cava (IVC) thrombosis. IVC thrombosis was confirmed by a bedside contrast media study (X-ray) demonstrating collateral paravertebral circulation along the paravertebral sinuses bilaterally into the azygos and hemiazygos vein (“rope ladder sign“), with no contrast media detected in the IVC. The infant was subsequently started on aspirin and clopidogrel.
Kv1.3 Channel Blockade Improves Inflammatory Profile, Reduces Cardiac Electrical Remodeling, and Prevents Arrhythmia in Type 2 Diabetic Rats
Authors: Zayas-Arrabal Julián , Alquiza Amaia , Rodríguez-de-Yurre Ainhoa , Echeazarra Leyre , Fernández-López Víctor , Gallego Mónica , Casis Oscar 
Published: October 2021

Abstract
Purpose
Kv1.3 channel regulates the activity of lymphocytes, macrophages, or adipose tissue and its blockade reduces inflammatory cytokine secretion and improves insulin sensitivity in animals with metabolic syndrome and in genetically obese mice. Thus, Kv1.3 blockade could be a strategy for the treatment of type 2 diabetes. Elevated circulating levels of TNFα and IL-1b mediate the higher susceptibility to cardiac arrhythmia in type 2 diabetic rats. We hypothesized that Kv1.3 channel blockade with the psoralen PAP1 could have immunomodulatory properties that prevent QTc prolongation and reduce the risk of arrhythmia in type 2 diabetic rats.

Methods
Type 2 diabetes was induced to Sprague-Dawley rats by high-fat diet and streptozotocin injection. Diabetic animals were untreated, treated with metformin, or treated with PAP1 for 4 weeks. Plasma glucose, insulin, cholesterol, triglycerides, and cytokine levels were measured using commercial kits. ECG were recorded weekly, and an arrhythmia-inducing protocol was performed at the end of the experimental period. Action potentials were recorded in isolated ventricular cardiomyocytes.

Results
In diabetic animals, PAP1 normalized glycaemia, insulin resistance, adiposity, and lipid profile. In addition, PAP1 prevented the diabetes-induced repolarization defects through reducing the secretion of the inflammatory cytokines IL-10, IL-12p70, GM-CSF, IFNγ, and TNFα. Moreover, compared to diabetic untreated and metformin-treated animals, those treated with PAP1 had the lowest risk of developing the life-threatening arrhythmia Torsade de Pointes under cardiac challenge.

Conclusion
Kv1.3 inhibition improves diabetes and diabetes-associated low-grade inflammation and cardiac electrical remodeling, resulting in more protection against cardiac arrhythmia compared to metformin.
Room-Temperature Metathesis of Ethylene with 2-Butene to Propene Over MoOx-Based Catalysts: Mixed Oxides as Perspective Support Materials
Authors: Otroshchenko Tatiana , Zhang Qiyang , Kondratenko Evgenii V. 
Published: October 2021

AbstractWe investigated the effect of supports based on ZrO2, TiO2, Al2O3, and SiO2 on the rate of propene formation in the metathesis of ethylene with 2-butene at 50 °C over Mo-containing catalysts possessing highly dispersed MoOx. Large improvements in this rate were achieved when using supports composed of mixed oxides (ZrO2–SiO2, ZrO2–PO4, TiO2–SiO2; Al2O3–SiO2) rather than of individual oxides (ZrO2, TiO2, Al2O3, SiO2). Although previous literature studies dealing with the metathesis reaction over Al2O3- or SiO2-suppported catalysts at higher temperatures suggest the importance of redox or acidic properties of supported MoOx species for catalyst activity, we were not able to establish any general direct correlation in this regard. Contrarily, the rate of propene formation can be significantly enhanced when promoting supports with an oxide promoter. We suggest that the created support lattice defects may facilitate the transformation of MoOx to Mo carbenes under reaction conditions or improve the intrinsic activity of the latter.
Graphic Abstract
The Short-Term Effects of European Integration on Mortality Convergence: A Case Study of European Union’s 2004 Enlargement
Authors: Hrzic Rok , Vogt Tobias , Brand Helmut , Janssen Fanny 
Published: October 2021

AbstractAlthough European integration can be expected to result in mortality convergence (reduced mortality differences), a life expectancy divide persists in the European Union (EU) between the old Member States (OMS) in the west and the new Member States (NMS) in the east. Studies investigating the impact of European integration on mortality convergence are rare and did not consider regional differences. We examine the short-term effects of the 2004 enlargement on mortality convergence at the supranational, national, and subnational levels. Using sex-specific life expectancies for 23 Member States (1990–2017) and the NUTS 2 regions in Czechia, Hungary, and Poland for 1992–2016, we examined the trend in sigma and beta mortality convergence measures at the country and regional levels using joinpoint regression. We found no compelling evidence that EU accession influenced the process of mortality convergence between OMS and NMS, or within the three NMS, over the short term. While there was overall beta and sigma convergence at the national level during 1990–2017, no regional convergence showed, and the trends in convergence did not significantly change at the time of EU accession or soon after (2004–2007). The accession in 2004 did not visibly impact the overall process of mortality convergence over the short term, likely because of the greater influence of country and region-specific policies and characteristics. The interaction of Member State and regional contexts with the mechanisms of European integration requires further study. Future enlargement procedures should emphasise tailored support to ensure more equitable gains from European integration.
Three decades of pastoralist settlement dynamics in the Ethiopian Omo Delta based on remote sensing data
Authors: Amos Samira , Mengistu Sileshi , Kleinschroth Fritz 
Published: October 2021

AbstractRiver deltas provide important livelihoods to local populations, but at the same time are under increasing anthropogenic pressure. The opening of the Gibe III dam on the Omo River in Ethiopia in 2016 attracted international attention due to the importance of the free-flowing River for pastoralist communities in the Omo Delta. Sustainable river basin management requires spatially explicit, long-term information about human settlements to mitigate negative impacts on people’s livelihoods. Based on remote sensing time-series, and supplemented with ground-truthing, we mapped settlement-dynamics of the pastoralist Dasanech tribe. The inhabited area more than doubled from 1992 to 2009. From 2009 to 2019, settlements became more permanent and concentrated in the North of the Delta. Our results indicate that the Omo Delta has overall gained in importance as a livelihood area, but that the livelihoods of the traditionally nomadic people are shifting in the context of increasing investment in infrastructure. Management of future river flow at dams should consider the location and the trajectory of change in downstream settlements.
Hypotension Prediction Index with non-invasive continuous arterial pressure waveforms (ClearSight): clinical performance in Gynaecologic Oncologic Surgery
Authors: Frassanito Luciano , Giuri Pietro Paolo , Vassalli Francesco , Piersanti Alessandra , Longo Alessia , Zanfini Bruno Antonio , Catarci Stefano , Fagotti Anna , Scambia Giovanni , Draisci Gaetano 
Published: October 2021

AbstractIntraoperative hypotension (IOH) is common during major surgery and is associated with a poor postoperative outcome. Hypotension Prediction Index (HPI) is an algorithm derived from machine learning that uses the arterial waveform to predict IOH. The aim of this study was to assess the diagnostic ability of HPI working with non-invasive ClearSight system in predicting impending hypotension in patients undergoing major gynaecologic oncologic surgery (GOS). In this retrospective analysis hemodynamic data were downloaded from an Edwards Lifesciences HemoSphere platform and analysed. Receiver operating characteristic curves were constructed to evaluate the performance of HPI working on the ClearSight pressure waveform in predicting hypotensive events, defined as mean arterial pressure < 65 mmHg for > 1 min. Sensitivity, specificity, positive predictive value and negative predictive value were computed at a cutpoint (the value which minimizes the difference between sensitivity and specificity). Thirty-one patients undergoing GOS were included in the analysis, 28 of which had complete data set. The HPI predicted hypotensive events with a sensitivity of 0.85 [95% confidence interval (CI) 0.73–0.94] and specificity of 0.85 (95% CI 0.74–0.95) 15 min before the event [area under the curve (AUC) 0.95 (95% CI 0.89–0.99)]; with a sensitivity of 0.82 (95% CI 0.71–0.92) and specificity of 0.83 (95% CI 0.71–0.93) 10 min before the event [AUC 0.9 (95% CI 0.83–0.97)]; and with a sensitivity of 0.86 (95% CI 0.78–0.93) and specificity 0.86 (95% CI 0.77–0.94) 5 min before the event [AUC 0.93 (95% CI 0.89–0.97)]. HPI provides accurate and continuous prediction of impending IOH before its occurrence in patients undergoing GOS in general anesthesia.
Heuristic Methods for Minimum-Cost Pipeline Network Design – a Node Valency Transfer Metaheuristic
Authors: Yeates Christopher , Schmidt-Hattenberger Cornelia , Weinzierl Wolfgang , Bruhn David 
Published: October 2021

AbstractDesigning low-cost network layouts is an essential step in planning linked infrastructure. For the case of capacitated trees, such as oil or gas pipeline networks, the cost is usually a function of both pipeline diameter (i.e. ability to carry flow or transferred capacity) and pipeline length. Even for the case of incompressible, steady flow, minimizing cost becomes particularly difficult as network topology itself dictates local flow material balances, rendering the optimization space non-linear. The combinatorial nature of potential trees requires the use of graph optimization heuristics to achieve good solutions in reasonable time. In this work we perform a comparison of known literature network optimization heuristics and metaheuristics for finding minimum-cost capacitated trees without Steiner nodes, and propose novel algorithms, including a metaheuristic based on transferring edges of high valency nodes. Our metaheuristic achieves performance above similar algorithms studied, especially for larger graphs, usually producing a significantly higher proportion of optimal solutions, while remaining in line with time-complexity of algorithms found in the literature. Data points for graph node positions and capacities are first randomly generated, and secondly obtained from the German emissions trading CO2 source registry. As political will for applications and storage for hard-to-abate industry CO2 emissions is growing, efficient network design methods become relevant for new large-scale CO2 pipeline networks.
Enhancing decision-making in user-centered web development: a methodology for card-sorting analysis
Authors: Macías José A. , Culén Alma L. 
Published: October 2021

AbstractThe World Wide Web has become a common platform for interactive software development. Most web applications feature custom user interfaces used by millions of people every day. Information architecture addresses the structural design of information to build quality web applications with improved usability of content, navigation, and findability. One of the most frequently utilized information architecture methods is card sorting—an affordable, user-centered approach for eliciting and evaluating categories and navigable items. Card sorting facilitates decision-making during the development process based on users’ mental models of a given application domain. However, although the qualitative analysis of card sorts has become common practice in information architecture, the quantitative analysis of card sorting is less widely applied. The reason for this gap is that quantitative analysis often requires the use of customized techniques to extract meaningful information for decision-making. To facilitate this process and support the structuring of information, we propose a methodology for the quantitative analysis of card-sorting results in this paper. The suggested approach can be systematically applied to provide clues and support for decisions. These might significantly impact the design and, thus, the final quality of the web application. Therefore, the approach includes proper goodness values that enable comparisons among the results of the methods and techniques used and ensure the suitability of the analyses performed. Two publicly available datasets were used to demonstrate the key issues related to the interpretation of card sorting results and the overall suitability and validity of the proposed methodology.
Chemical decarboxylation kinetics and identification of amino acid standards by benchtop NMR spectroscopy
Authors: Czajkowska Angelika , Dayi Defne Ilayda , Weinschrott Helga , Deigner Hans-Peter , Schmidt Magnus S. 
Published: October 2021

AbstractIn this paper, we examined the competence of amino acids as standards for instrumental biochemical analysis. The chosen amino acids were first dissolved in various aquatic solutions and then measured in a benchtop NMR spectrometer, which is not a common choice in such analytical investigations. Analysis by mass spectrometry was used in addition. As part of these investigations, we examined and determined the stability of the amino acids ornithine, glutamic acid, alanine, glycine, proline, pyroglutamic acid, phenylalanine and trans-4-hydroxy-D-proline under critical basic and acidic pH conditions and under various other conditions. We observed that not all solutions of the amino acid standards remain stable under the given conditions and a chemical transformation takes place. Given our findings by mass spectroscopy, additional kinetic measurements were carried out with the benchtop NMR spectrometer. We discovered that pyroglutamic acid becomes unstable under basic conditions and decarboxylates to pyrrolidone.
Does official development assistance affect a donor’s exports? South Korea’s case
Authors: Noh Bobae , Heshmati Almas 
Published: October 2021

AbstractThis paper studies the impact of official development assistance (ODA) provided by South Korea for its exports to recipient countries. The empirical analysis is based on data from 1996 to 2014 and covers 121 recipient countries. The paper uses a 3SLS estimation method that accounts for a two-way causal relationship between ODA and exports while the endogeneity and sample selection bias are accounted for. Using the gravity model, we confirm the positive effects of ODA when fixed unobserved effects are controlled. The model is further generalized by disaggregating ODA into its underlying types of aid. Our results show that technical cooperation and loans have positive and significant effects, but grants have a negative impact on South Korea’s exports to recipient countries. In addition, we also examine South Korea’s ODA allocations. Our findings suggest that there is a two-stage decision-making process in the provision of aid. In the first stage, the aid’s humanitarian purpose plays a key role in responding to countries’ needs even when there is lower bilateral trade with these countries. In the second stage, decisions regarding the size of ODA are considered and these present a mixed purpose for giving ODA to higher importer countries.
Sexual Response Differs During Partnered Sex and Masturbation in Men with and Without Sexual Dysfunction: Implications for Treatment
Authors: Rowland David L. , Hamilton Benjamin D. , Bacys Katelyn R. , Hevesi Krizstina 
Published: October 2021

ABSTRACTBackgroundIt is unclear whether men who experience sexual difficulty during partnered sex experience similar difficulty during masturbation.AimTo determine whether sexual functionality and dysfunctionality were similar or different during masturbation vs partnered sex.MethodsWe compared sexual responsivity during masturbation vs partnered sex in a multinational sample of 4,209 men with and without a sexual dysfunction to determine whether dysfunctionality was greater, less, or about the same during these 2 types of sexual activity.OutcomesConsistently lower impairment of sexual function was found during masturbation compared with partnered sex for all 3 sexual problems assessed: erectile dysfunction, premature ejaculation, and delayed ejaculation.Clinical TranslationThese findings reiterate the potential value of assessing sexual responsivity during masturbation as well as melding masturbation strategies with couples therapy in order to attenuate impaired response during partnered sex.Strength & LimitationsAlthough this study provides the first empirical evidence based on a large multinational sample indicating that sexual functionality is consistently higher during masturbation than partnered sex, it does not provide an empirically-derived explanation for this difference.CONCLUSIONUnderstanding a man’s response potential during masturbation may be important to improving sexual response during partnered sex, with the need for more targeted research that more directly evaluates the use of such strategies in the treatment of men’s sexual problems.
Analysis and extension of the quadratic constitutive relation for RANS methods
Authors: Sabnis K. , Babinsky H. , Spalart P.R. , Galbraith D.S. , Benek J.A. 
Published: October 2021

AbstractThe quadratic constitutive relation was proposed as an extension of minimal complexity to linear eddy-viscosity models in order to improve mean flow predictions by better estimating turbulent stress distributions. However, the successes of this modification have been relatively modest and are limited to improved calculations of flow along streamwise corners, which are influenced by weak secondary vortices. This paper revisits the quadratic constitutive relation in an attempt to explain its capabilities and deficiencies. The success in streamwise corner flows cannot be entirely explained by significant improvements in turbulent stress estimates in general, but is instead due to better prediction of the particular turbulent stress combinations which appear in the mean streamwise vorticity equation. As a consequence of this investigation, a new formulation of turbulent stress modification is proposed, which appears to better predict the turbulent stress distributions for a variety of flows: channel flow, equilibrium boundary layers, pipe flow, separated boundary layers and square duct flow.
Optimisation analysis of reinforced cable distribution on the airship
Authors: Zhao H. , Chen Z. , Chen J. 
Published: October 2021

AbstractReinforced cables are usually installed on flexible airship structures to enhance their load-bearing capability. However, reinforced cables also increase the total weight of the airship. In order to find a balance between large loading-bear capability and light weight, a multi-objective optimisation scheme based on the genetic algorithm NSGA-II is put forward for the reinforced cable distribution on the airship. Firstly, different cable distribution schemes are presented according to engineering experience and the optimal one is determined by load analysis. Then, the CAE method and optimisation analysis are combined to achieve structure design optimisation. The parametric model of the airship structure with reinforced cables is established by ABAQUS secondary development and the load analysis is carried out. Parameter passing and optimisation algorithm are operated by Isight software and the optimisation analysis is conducted based on the NSGA-II algorithm. Finally, we draw some conclusions of the rules of optimised reinforcing cable distribution. The work of this paper has crucial engineering significance for improving performance of the airship structure design.
On spatial matchings: The first-in-first-match case
Authors: Manjrekar Mayank 
Published: October 2021

AbstractWe describe a process where two types of particles, marked red and blue, arrive in a domain at a constant rate. When a new particle arrives into the domain, if there are particles of the opposite color present within a distance of 1 from the new particle, then, among these particles, it matches to the one with the earliest arrival time, and both particles are removed. Otherwise, the particle is simply added to the system. Additionally, particles may lose patience and depart at a constant rate. We study the existence of a stationary regime for this process, when the domain is either a compact space or a Euclidean space. In the compact setting, we give a product-form characterization of the stationary distribution, and then prove an FKG-type inequality that establishes certain clustering properties of the particles in the steady state.