bluuebunny/crossref_metadata_2025_split huggingface dataset:
Women empowerment and uptake of antenatal care services : A meta-analysis of Demographic and Health Surveys from 33 Sub-Saharan African countries
Authors: Shibre Gebretsadik , Zegeye Betregiorgis , Yeboah Helena , Bisjawit Ghose , Ameyaw Edward Kwabena , Yaya Sanni 
Published: May 2021

Abstract
Background
Women empowerment has been linked to increased skilled antenatal care (ANC) service use. However, there is no evidence on the net effect of women empowerment on ANC in the Sub-saharan African (SSA) region. We aim to address the knowledge gap on whether or not women empowerment positively influences the uptake of ANC at the SSA regional level.

Methods
We analyzed the Demographic Health Survey (DHS) datasets from 33 SSA countries. Following the DHS data analysis guideline, we measured women empowerment using two indicators. The first indicator is an index, which comprises decision-making on women’s own health, household purchase and visit to family or relatives whilst disagreeing statements that husband is justified in beating his wife constitutes the second indictor. We performed confounder-adjusted logistic regression analysis for the two indicators with ANC attendance in each of the 33 countries. Then, we pooled the adjusted Odds Ratios (OR) using the random effect model through the two-stage Individual Participant Data meta-analysis technique. Summary findings are reported in OR and corresponding 95 %CI and are presented in a forest plot.

Results
Moderately empowered women had marginally higher odd of skilled ANC service across the SSA region (aOR = 1.19; 95 %CI: 1.03, 1.38, with a prediction interval of 0.58, 2.45). Conversely, being involved in the three decisions (aOR = 1.15; 95 %CI: 0.99, 1.33, with prediction interval 0.57, 2.31), and attitude towards wife-beating (aOR = 0.97; 95 %CI: 0.88, 1.06, with prediction interval of 0.63, 1.48) had no statistically significant relationship with ANC.

Conclusions
Women empowerment did not predict the use of skilled ANC in the context of the SSA region. We recommend that further studies be conducted in order to understand how women empowerment affects skilled ANC service utilization in the region.
Acoustic telemetry detection probability and location accuracy in a freshwater wetland embayment
Authors: Stott Nathan D. , Faust Matthew D. , Vandergoot Christopher S. , Miner Jeffrey G. 
Published: May 2021

Abstract
Background
In recent years, large-scale acoustic telemetry observation networks have become established globally to gain a better understanding of the ecology, movements and population dynamics of fish stocks. When studying a species that uses different habitats throughout its life history difficulty may arise where acoustically suboptimal habitats are used, such as shallow, vegetated areas. To test the feasibility of active tracking in these acoustically suboptimal habitats, we quantified detection probability and location error as a function of several environmental variables with two transmitter types in a shallow freshwater embayment.

Results
When placed in nearshore areas (< 1 m deep), the higher-powered transmitter (158 dB) had significantly greater detection probability than the lower-powered transmitter (152 dB). For both transmitter types, detection probability declined at 200 m; however, at the 100 m distance the higher-powered transmitter had greater than 50% detection probability per ping cycle (50.4%) while the lower-powered transmitter was substantially less (29.4%). Additionally, detection probability increased when the transmitter was deployed within sparse, senescent Phragmites spp. vegetation (14%). Estimated positional accuracy of transmitters deployed at known locations (location error) was variable (error range: 13–259 m), and was generally higher for the more powerful transmitter. Location error was minimized when the lower-powered transmitter was located near softened shoreline areas compared to near man-made armored shorelines (i.e., rip-rap).

Conclusion
While benefits exist for maximizing transmitter power (e.g., increased detection range in open-water environments), use of a lower-powered transmitter may be advantageous for active tracking specific locations of fish inhabiting shallow water environments, such as in estuarine tidal marshes and shallow wetlands. Thus, when planning acoustic telemetry studies, researchers should conduct site-specific preliminary detection probability/location error experiments to better understand the utility of acoustic telemetry to investigate fish movements in acoustically suboptimal conditions.
Development and validation of stability-indicating RP-HPLC method for the simultaneous estimation of xylometazoline hydrochloride and ipratropium bromide from nasal spray dosage form
Authors: Musmade Bhaskar , Sanatan Prashant , Lokhande Surbhi , Kulkarni Shrikant , Bhope Shrinivas , Padmanabhan Sriram , Pachpinde Amol , Lohar Kishan 
Published: May 2021

Abstract
Background
A simple, robust, precise, and an accurate HPLC method was established for simultaneous estimation of xylometazoline hydrochloride and ipratropium bromide from a nasal spray dosage form. The effective separation was obtained by injecting 10 μl of sample and standard solutions on to an Inertsil ODS column, 250 × 4.6, mm, 5 μ at 45 °C using phosphate buffer with 1-pentane sulphonic acid sodium salt at pH 4.7 as a mobile phase A and acetonitrile as the mobile phase B. The gradient was optimized with a flow rate of 1 mL/min and a wavelength of 210.0 nm.

Result
The complete analytical method validation was successfully carried out as per ICH guidelines. The retrieval study was carried out at 50% to 150% level of working concentration, and results were in the range of 99 to 101% for both the analytes. The linearity was proven from 4 to 150% of working concentration with linear regression curve (R2=0.999) for both the analytes. The developed method was robust for different parameters like column temperature, flow rate, mobile phase pH, composition, and gradient.

Conclusion
The developed HPLC method can be successfully used for the estimation of xylometazoline hydrochloride and ipratropium bromide from nasal spray dosage form as a release test in QC department of manufacturing units.
Efficacy of a food supplement Lertal® as an adjuvant therapy of patients with moderate-to-severe seasonal allergic rhinoconjunctivitis
Authors: Perić Aleksandar , Čupić Maja Buljčik , Vuković Marija Komadina , Dragović Vesna Gajić , Nešić Vladimir , Lekić Nenad 
Published: May 2021

Abstract
Background
Lertal® is an oral food supplement containing 80 mg of dry extract of Perilla frutescens, 150 mg of bioflavonoid quercetin, and 5 μg of vitamin D3. The aim of this study was to evaluate the efficacy of Lertal® as a complementary therapy to topical therapy of patients with moderate-to-severe seasonal allergic rhinoconjunctivitis (SAR).

Results
Seventy (n=70) adult patients with moderate-to-severe SAR were included in this prospective study and treated by four different procedures: (1) 21 patients received azelastine intranasal spray for 30 days and, after that, azelastine spray and Lertal® tablets for the next 30 days; (2) 19 patients received combined azelastine with fluticasone intranasal spray for 30 days and azelastine with fluticasone spray and Lertal® tablets for the next 30 days; (3) 15 patients received azelastine spray only for 60 days; (4) 15 patients received combined azelastine with fluticasone spray only for 60 days. Levels of SAR symptoms (sneezing, tearing, ocular itching, rhinorrhea, nasal obstruction, hyposmia, and cough), as well as Total Symptom Scores (TSS), were evaluated at the start of this investigation (visit 0), after 30 days of treatment (visit 1), and after 60 days of treatment (visit 2) using a visual analog scale. After 30 days of treatment, better effects were achieved in groups in which patients were treated with combined (antihistamine with corticosteroid) spray. After 60 days of therapy, we found the best effects in procedure 2 and slightly worse effects in procedure 1. The high differences in the reduction of TSS between the 60th and 30th day were found for procedure 2 (p<0.001) and procedure 1 (p<0.001). The worse improvement of symptoms we found was in procedure 4 (p<0.01), and, for the procedure 3, we found no significant difference (p=0.140). None of the patients reported adverse effects during the therapy.

Conclusion
Our results suggest that addition of food supplement Lertal® to the standard topical therapy of patients with moderate-to-severe SAR increases the effects of intranasal therapy in reducing nasal and ocular symptoms.
Changes in HIV-Related Cervical Cancer Over a Decade in Côte d'Ivoire
Authors: Jaquet Antoine , Boni Simon , Tchounga Boris , Comoe Kouassi , Tanon Aristophane , Horo Apollinaire , Diomandé Isidore , Didi-Kouko Coulibaly Judith , Ekouevi Didier K. , Adoubi Innocent 
Published: May 2021

PURPOSE Major improvements have occurred in access to invasive cervical cancer (ICC) screening in HIV-infected women over the past decade in sub-Saharan Africa. However, there is limited information on changes in the burden of HIV-related ICC at a population level. Our objective was to compare HIV-related ICC over a decade and document factors associated with HIV infection in women with ICC in Côte d'Ivoire. METHODS A repeated cross-sectional study was conducted in referral hospitals of Abidjan, Côte d'Ivoire, through the 2009-2011 and 2018-2020 periods. Women diagnosed with ICC were systematically tested for HIV. Demographics, ICC risk factors, cancer stage (International Federation of Gynecology and Obstetrics), and HIV characteristics were collected through questionnaires. Characteristics of HIV-related ICC were compared between the periods, and factors associated with HIV in women diagnosed with ICC in 2018-2020 were documented through a multivariable logistic model. RESULTS During the 2009-2011 and 2018-2020 periods, 147 and 297 women with ICC were diagnosed with estimated HIV prevalence of 24.5% and 21.9% ( P = .53), respectively. In HIV-infected women, access to antiretroviral treatment increased from 2.8% to 73.8% ( P < 10−4) and median CD4 cell count from 285 (IQR, 250-441) to 492 (IQR, 377-833) cells/mm3 ( P = .03). In women diagnosed with ICC during the 2018-2020 period, HIV infection was associated with a less advanced clinical stage (International Federation of Gynecology and Obstetrics I or II stage) (adjusted OR, 2.2 [95% CI, 1.1 to 4.4]) and with ICC diagnosis through a systematic screening (adjusted OR, 10.5 [95% CI, 2.5 to 45.5]). CONCLUSION Despite a persistently high proportion of HIV-related ICC over time in Côte d'Ivoire, HIV was associated with less advanced clinical stage at ICC diagnosis. Recent improvements in ICC screening services across HIV clinics might explain this association and support their implementation across non-HIV health facilities.
Anticolonialism and the Decolonization of Political Theory
Authors: Getachew Adom , Mantena Karuna 
Published: May 2021

AbstractThis essay surveys some recent attempts to decolonize political theory and engage with non-Western political thinkers and traditions, especially anticolonialism. The authors' concern is that these engagements remain too centered on Western political thought as the object of critique and analysis. Through a reading of Gandhi and Fanon, the authors argue that anticolonialism, while engaged in a critique of the West, also had a positive or reconstructive theoretical agenda, one that has been taken up in creative ways in postcolonial political thought. Taking cues from the work of Sudipta Kaviraj, Partha Chatterjee, and Mahmood Mamdani, the essay proposes an alternative mode of decolonizing political theory that takes as its central aim the generation of theory from the study of postcolonial politics. It argues for a historically attuned and comparative approach to postcolonial politics that aims to innovate new concepts and reanimate inherited ones. From this perspective, decolonizing political theory is less a recurring critique of Eurocentrism than an effort to shift the terrain of theorizing and thereby reinvigorate the practice of political theory as such.
Transcriptomic analyses of gastrulation-stage mouse embryos with differential susceptibility to alcohol
Authors: Boschen Karen E. , Ptacek Travis S. , Berginski Matthew E. , Simon Jeremy M. , Parnell Scott E. 
Published: May 2021

ABSTRACTGenetics are a known contributor to differences in alcohol sensitivity in humans with fetal alcohol spectrum disorders (FASDs) and in animal models. Our study profiled gene expression in gastrulation-stage embryos from two commonly used, genetically similar mouse substrains, C57BL/6J (6J) and C57BL/6NHsd (6N), that differ in alcohol sensitivity. First, we established normal gene expression patterns at three finely resolved time points during gastrulation and developed a web-based interactive tool. Baseline transcriptional differences across strains were associated with immune signaling. Second, we examined the gene networks impacted by alcohol in each strain. Alcohol caused a more pronounced transcriptional effect in the 6J versus 6N mice, matching the increased susceptibility of the 6J mice. The 6J strain exhibited dysregulation of pathways related to cell death, proliferation, morphogenic signaling and craniofacial defects, while the 6N strain showed enrichment of hypoxia and cellular metabolism pathways. These datasets provide insight into the changing transcriptional landscape across mouse gastrulation, establish a valuable resource that enables the discovery of candidate genes that may modify alcohol susceptibility that can be validated in humans, and identify novel pathogenic mechanisms of alcohol.This article has an associated First Person interview with the first author of the paper.
Digitization and Pre-Purchase Information: The Causal and Welfare Impacts of Reviews and Crowd Ratings
Authors: Reimers Imke , Waldfogel Joel 
Published: May 2021

Digitization has led to many new creative products, straining the capacity of professional critics and consumers. Yet, the digitization of retailing has also delivered new crowd-based sources of pre-purchase information. We compare the relative impacts of professional critics and crowd-based Amazon star ratings on consumer welfare in book publishing. Using various fixed effects and discontinuity-based empirical strategies, we estimate their causal impacts on sales. We use these causal estimates to calibrate a structural demand model. The aggregate effect of star ratings on consumer surplus is, in our baseline estimates, more than ten times the effect of traditional review outlets. (JEL D83, L15, L81, L82)
Incidence and predictors of Adverse Drug Reaction (ADR) among adult HIV positive patients on anti-retroviral treatment in Arba Minch town public health facilities, southern Ethiopia: A retrospective cohort study, 2020
Authors: Sherfa Abdulbasit , Haile Dereje , Yihune Menaye , Sako Sewenet 
Published: May 2021

Background
Besides its contribution in the treatment of Human Immunodeficiency Virus-infected patients, anti-retroviral drugs may also cause mild to serious adverse effects. It is the main causes for poor drug adherence, treatment discontinuation and changes in Anti-Retroviral Treatment (ART) regimens. Thus, the aim of this study was to assess the incidence and predictors of adverse drug reaction among adult Human Immunodeficiency Virus positive patients on anti-retroviral treatment from January 1, 2013 up to December 30, 2018 at Arba Minch town public health facilities, Southern Ethiopia.

Methods
An institution based retrospective cohort study was conducted on 456 charts. Secondary data was collected by structured questionnaire. Data were entered in Epi-data version 4.4.2 software and exported to STATA Version 14 for analysis. The Kaplan-Meier survival curve with Log-rank was used to estimate survival time. Bi-variable and multivariable Cox proportional hazard regression models were fitted to identify predictors of adverse drug reaction. In the bi-variable analysis, the variables with p-value < 0.25 were eligible for multivariable analysis. Finally, variables with p-values less than 0.05 in the multivariable Cox regression were considered as independent predictors. The statistical significance was declared at p-value<0.05.

Results
Out of 456 patients observed for 14,903 person-months (pm), 79 experienced adverse drug reactions and the overall incidence density rate was 0.53/100 pm, CI: 0.42–0.66/100 person’s month or 6.36 per 100 Pearson year of observation. Females were at higher risk of experiencing adverse drug reactions (ADRs) compared to males [AHR = 2.35; CI (1.18, 4.69)]. The risk of experiencing ADRs among patient with advanced WHO clinical stage (stage III and IV) was higher compared to stage I and II [AHR = 3.0, CI (1.22, 7.37)]. The risk of experiencing an ADR was at any given time higher among AZT and NVP containing regimens compared to TDF and EFV containing regimens. Finally, the risk of ADR among those patients from the health center was reduced by 59% compared to hospital patients, [AHR = 0.41, CI (0.17, 0.97)].

Conclusion and recommendation
The incidence rate of ADRs was reduced among patients on ARVs compared to previous studies and it was high during the early years of ART initiation. HIV patients should be closely followed in the early years of ART initiation, since this is the time of highest risk ADRs and emphasis should be given for female and clinically advanced patients.
Incidence of non-communicable diseases (NCDs) in HIV patients on ART in a developing country: Case of Zimbabwe’s Chitungwiza Central Hospital—A retrospective cohort study (2010–2019)
Authors: Cheza Alexander , Tlou Boikhutso , Zhou Danai Tavonga 
Published: May 2021

Introduction
The incidence of non-communicable diseases (NCDs) has been reported to be rising over the years leading up to 2010. In Zimbabwe, there are few studies done to examine the incidence of NCDs in people living with HIV (PLHIV) on anti-retroviral treatment (ART).

Objective
To determine the incidence of NCDs in HIV patients on ART at the Chitungwiza Central Hospital over ten years and the associated risk factors.

Methods
This was a retrospective cohort study using data from 203 patients enrolled on ART at the Chitungwiza Central Hospital between 2010 and 2019. All 500 records were considered and the selection was based on participants’ consenting to the study and their strict adherence to ART without absconding. The incidence of NCDs was determined and generalized estimating equations (GEE) were used to estimate the association between NCDs and the selected risk factors.

Findings
Data collected at the study’s baseline (2010) showed that the most prevalent NCD was hypertension, found in (18/203) 8.9% of the study participants, followed by diabetes (6.9%), then followed by cardiovascular diseases (CVD) (3.9%), and the least common NCD was cancer (1.9%). Incidences of all of these NCDs showed an increasing trend as the time of follow-up progressed. The factors found to be significantly associated with the development of NCDs were gender (p = 0.002) and follow-up time (p<0.001). Geographical location was a significant risk factor as urban patients were more likely to develop hypertension as compared to the peri-urban patients (p = 0.001).

Conclusions
NCDs and HIV comorbidity is common with women more likely than males to develop NCDs as they advance in age. There is need to devise targeted intervention approach to the respective NCDs and risk factors since they affect differently in relation to the demographic details of the participants.

Recommendations
This paper recommends a multi-stakeholder approach to the management of NCDs, with researchers, clinicians and the government and its various arms taking a leading role.
Social capital and cognitive decline: Does sleep duration mediate the association?
Authors: Wang Liqun , Li Jiangping , Wang Zhizhong , Du Yong , Sun Ting , Na Li , Niu Yang 
Published: May 2021

BackgroundStudies have found that social capital (SC) is associated with the risk of cognitive decline; however, the mechanism explaining how SC leads to cognitive decline is unclear. The current study examines the mediation effect of sleep duration on the relationship between SC and cognitive decline in Chinese older adults.MethodsA cross-sectional study of 955 community-dwelling aged 60 or over was conducted. The mini-mental state examination (MMSE), self-report sleep duration questionnaire, and social capital scales were administered during the face-to-face survey. The Bootstrap methods PROCESS program is employed to test the mediation model.ResultsAfter controlling for covariates, both social cohesion and social interaction were positively correlated with the MMSE score (p<0.001), and social cohesion was negatively correlated with sleep duration (p = 0.009); On the contrary, sleep duration was negatively correlated with MMSE score (p<0.001). Linear regression analysis showed social cohesion was positively associated with the MMSE score (β = 0.16, p = 0.005), while sleep duration was associated with an increased risk of cognitive decline (β = -0.72, p<0.001). Sleep duration has mediated the relationship between social cohesion and cognitive decline (explaining 21.7% of the total variance).ConclusionsSocial capital negatively associated with the risk of cognitive decline in this Chinese population, and sleep duration may partly explain this relationship. It may be a suggestive clue to identify those at a higher risk of progressing to cognitive impairment. Further prospective study in need to confirm this finding due to the cross-sectional design.
Evaluation of four point cloud similarity measures for the use in autonomous driving
Authors: Berens Felix , Elser Stefan , Reischl Markus 
Published: May 2021

Abstract
Measuring the similarity between point clouds is required in many areas. In autonomous driving, point clouds for 3D perception are estimated from camera images but these estimations are error-prone. Furthermore, there is a lack of measures for quality quantification using ground truth. In this paper, we derive conditions point cloud comparisons need to fulfill and accordingly evaluate the Chamfer distance, a lower bound of the Gromov Wasserstein metric, and the ratio measure. We show that the ratio measure is not affected by erroneous points and therefore introduce the new measure “average ratio”. All measures are evaluated and compared using exemplary point clouds. We discuss characteristics, advantages and drawbacks with respect to interpretability, noise resistance, environmental representation, and computation.
Fehlertoleranz in kooperierenden Regelungssystemen durch Umverteilung der Regelungsaufgaben
Authors: Schenk Kai , Lunze Jan 
Published: May 2021

Zusammenfassung
Dieser Beitrag befasst sich mit vernetzten Regelungssystemen, die eine kooperative Aufgabe erfüllen müssen. Den Teilsystemen (Agenten) werden situationsabhängig Aufgaben zugewiesen, die von einer Koordinierungseinheit so gewählt sind, dass die kooperative Aufgabe stets erfüllt wird. Wenn Agenten defekt sind, werden die Aufgaben der gesunden Agenten so angepasst, dass der Ausfall der Agenten keine Auswirkung auf die kooperative Aufgabe hat. Es werden zwei neue Methoden für diese Umverteilung der Regelungsaufgaben vorgestellt. Ein Transportsystem wird zur Veranschaulichung der Methoden genutzt.