bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Role of Clinical Pharmacist in Enhancement of Medication Adherence and Quality of Life in Bronchial Asthma and Chronic Obstructive Pulmonary Disease
Authors: Gangadharan Aswathi , Thomas Diya Sheela , Harshida , , Tom Cyril , Adake Prabhakar 
Published: August 2021

Asthma and Chronic Obstructive Pulmonary Disease (COPD) are two of the leading causes of morbidity, mortality and economic burden worldwide. The burden of chronic respiratory disease has major adverse effects on the quality of life and ability of affected individuals. A variety of effective treatment options exist for patients with Asthma and COPD but long-term adherence to medications is required for treatment success. Aim of the study was to assess the adherence to medication and quality of life in Asthma and COPD patients using questionnaires, and to enhance adherence and quality of life using the strategies of counselling and education. The observational study was conducted for a period of 6 months, assessed medication adherence by Morisky self-reported questionnaires and quality of life by St. George’s Respiratory questionnaire (SGRQ) and 36 item short form health survey (SF-36). The study shows there was statistically significant improvement in medication adherence score (p<0.05) and quality of life (p<0.05) after pharmacist’s counselling regarding disease, medication and lifestyle. Comparison between various demographic factors like age, gender, co-morbidities, smoking index showed equal impact of pharmacist’s counselling on improvement of overall medication adherence and quality of life in Asthma and COPD patients. Overall medication adherence and quality of life improvement was found to be statistically significant in Asthma and COPD patients after counselling by clinical pharmacists. Clinical pharmacists must be considered as an integral element of healthcare system. Patient counselling is effective to resolve the problems associated with medication non-adherence and quality of life.
Keywords: Asthma, COPD, Medication adherence, Quality of life
Formulation and Evaluation of Lamivudine Nanosuspension
Authors: Ramesh Yerikala , Sarayu Ballem , Hari Chandana Guduru , Neelima Obili , Sana Shaik 
Published: August 2021

The present research aimed to develop & Evaluation of Lamivudine Nanosuspension. Lamivudine is a potent in vitro inhibitor of human immune deficiency virus belongs to the category of anti-retroviral drugs. The formulated Nanosuspension was subjected to various evaluation parameters like particle size, polydispersity index, zeta potential, drug content, viscosity, saturation solubility studies, In vitro release, treatment of kinetic data, and stability studies. The polydispersity ranged from 0.218 PDI to 0.331 PDI and zeta potential ranged from -1.60 mV to -4.79 mV are the important evaluation parameters are responsible for the stability of nanosuspensions. The Polydispersity index presents the quantity of particle size distribution ranges from 452.4 nm to 532.2 nm. In this result, LNSF4 shows spectacular drug content range of 86±1.8% to 97±2.5% it is the maximum drug content. The Brook field viscometer to determine the viscosity of Lamivudine Nano suspension of different formulations was found to be 44.4±2.1 cps to 87.7±1.4 cps. The general Nanosuspension formulations LNSF4 shows 98.64 % better controlled released in comparison with abundant formulation. In all the cases the best-fit model encounter uoto be peppas with ‘n’ value between 0.768 to 0.917. The ‘n’ value of formulation LNSF4 was 0.876 and suggesting so the drug was released by Zero-order kinetics. Acceleration stability studies intermediate storage condition has been changed from 30°C ± 2°C and 60% RH ± 5% Relative Humidity. After a 90 days study it revolves that there’s no change in Drug content, In vitro drug release, and particle size.
Keywords: Lamivudine, Nanosuspension, Saturation solubility, Scanning Electron Microscopy, Stability study.
Pharmacological evaluation for Anti-Anxiety and CNS depressant activity of hydro-alcoholic leaves extract of Pongamia pinnata
Authors: Panda Jagannath , Samantaray Biswajit , Pattnaik Gurudutta 
Published: August 2021

The aim of this study was to assess the anti-anxiety and CNS depressant properties of hydro-alcoholic extract of Pongamia pinnata leaves (HALEPP). Standard methods were used to screen the HALEPP's phytochemicals, which showed that the extract contains Flavones, alkaloids, glycosides, proteins and amino acids, gum and mucilage as well as flavonoids, saponins, and steroid hormones. Even at the dose level of 1000 mg/kg body weight, the HALEPP showed no signs of toxicity or mortality in the acute toxicity report. The anti-anxiety behaviour of was studied using light and dark model methods in rats. The CNS depressant action was studied using the extract and actophotometer (Rolex) in rats. The research group (HALEPP 200 gm/kg treated) animals displayed strong anti-anxiety and CNS depressant behaviour similar to the control group (diazepam treated) animals in the current study. The study's findings suggest that the hydro-alcoholic Pongamia pinnata leaf extract has strong anti-anxiety and CNS depressant properties.
Keywords: Pongamia pinnata, Anti-Anxiety & CNS depressant
Content Validity Determination of the Suicidal Ideation Behaviour Assessment Instruments Using Content Validity Ratio (CVR) Formula
Authors: Norshahira Osman , Norashida S. R., , Lukman Z. M. 
Published: August 2021

Drug addiction problems have been identified as one of the high-risk factors closely linked to suicidal behaviour. Early detection of suicidal intent among addicts is important to ensure they do not take actions that could result in death. Accordingly, this study aimed to Suicidal Ideation Behaviour Assessment (SIBA) instruments specifically among 123 treated addicts in Cure and Care Rehabilitation Centre (CCRC), Besut. Based on those statements, the main objective of this study was to determine the content validity of SIBA instruments for using the content validation Ratio (CVR) method. Subjects that were involved in conducting the trial of the instruments were 8 experts from UniSZA, UPSI and UMT. The instrument validation process involved 40 items from four components. The previous study found that the instrument had high validity with the minimum level of CVR value (N=8, CVR = 0.88). Generally, all items were identified with values above 0.63 rated acceptable and no item has been rejected occur. The result showed that the instrument is appropriate, relevant, has the potential to be a good content validity and proved that SIBA has a great potential to be promoted as a good instrument. This study was conducted to detect intoxication of their suicidal ideation among drug addicts. This psychometric instrument is developed based on the situation in Malaysia. This study is expected to make a significant contribution to the government, especially the CCRC in assisting addicts with suicidal ideation behaviour by providing better attention and psychosocial support services.
Keywords: Suicide ideation, drug addict, content validity ratio, instrument
The Relationship of Knowledge, Attitudes, and Practices of Fe Tablet Consumption of Mothers with Toddlers with Stunting Incidences in Cilembu Village, Sumedang Regency in 2019
Authors: Suryanegara Wiradi , Wija Ida Bagus Eka Utama 
Published: August 2021

Figures stunting in Indonesia did not experience a significant decline in 2007, 2010, and 2013. Where in 2007, the figure stunting in Indonesia is 36.8%. Whereas in 2010 and 2013, each of which has a percentage of 35.6% and 37.2%. Riskesdas in 2013 researched and found that the incidence of anaemia in pregnant women is at 37.1%, and in 2018 the prevalence of anaemia in the pregnant women group increased to 48.9%. This study aims to determine the relationship between Fe tablet consumption's knowledge, attitudes, and practices in mothers with toddlers with stunting incidents in Cilembu village, Sumedang district, in 2019. The method used is the analytic study of cross pieces (cross-sectional). The number of samples in this study was 45 respondents taken by non-random sampling with the purposive sampling method. Based on the data analysis, no relationship between knowledge, attitudes, and practices of Fe tablet consumption in mothers with toddlers with stunting incidents in Cilembu village, Sumedang district in 2019 (p value> 0.05). There is no relationship between Fe tablet consumption knowledge, attitudes, and practices in mothers with toddlers with stunting incidents in Cilembu village, Sumedang district in 2019.
Keywords: Knowledge, Attitude, Practice, Tablet Fe, Stunting
Analisis Kelainan Jantung Menggunakan Dimensi Fraktal Dan Transformasi Wavelet
Authors: Oktaviani D R , Habiburrohman M 
Published: August 2021

ABSTRACT
The disease that causes the largest number of deaths in Indonesia to date is acute coronary syndrome or called the silence killer. Deaths due to coronary heart disease (CHD) reached 26.4%. Therefore, to prevent the high death rate from CHD, early detection of CHD can be done. One way that can be done is checking the ECG (electrocardiogram / electrocardiograph) record. Then by using the HRV (Heart Rate Variability) method, which is to analyze the ECG signal which can take measurements, physiological interpretation, and clinical use of the ECG signal so that it can find out an arrhythmia (a condition in which the heart beats erratically) a person's heart and take medical steps right. In this article using wavelet transform analysis to identify heart disease. The results are then compared with the fractal dimensions of the heart rate signal. FD identifies heart disease with more than 90% confidence
Keywords : Fractal, Heart, Wavelet.
Sistem Pemesanan Drive Thru Menggunakan Lcd Touchscreen Berbasis Mikrokontroler
Authors: Nur Fatihah Utari , Hastuti Hastuti 
Published: August 2021

Pada saat ini belum banyak perusahaan makanan menggunakan proses pemesanan melalui sistem drive thru. Dengan menggunakan sistem drive thru ini maka suatu restoran dapat meningkatkan hasil penjualannya karena lebih memudahkan konsumen dalam memesan makanan. Tugas akhir ini bertujuan untuk membuat dan menguji sistem pemesanan drive thru di restoran menggunakan LCD touchscreen berbasis mikrokontroler. Metode yang digunakan adalah dengan cara merancang, membuat, dan melakukan pengujian hardware dan software untuk bisa diterapkan dalam sistem pemesanan drive thru. Sistem pemesanan drive thru ini menggunakan LCD touchscreen sebagai alat memesan menu pada pemesanan dan juga sebagai tampilan menu yang telah dipesan pada layar koki. Bluetooth HC-05 sebagai penghubung antara pemesanan dengan koki. Untuk pusat kontrol dari sistem pemesanan menggunakan mikrokontroler arduino mega 2560. Hasil dari sistem pemesanan drive thru ini adalah dapat memesan makanan menggunakan LCD touchscreen pada pemesanan dan juga dapat menampilkan pesanan di LCD koki.
Rancang Bangun Kontrol Pintu Air Dan Monitoring Ketinggian Air Sungai Berbasis Internet of Things (IoT)
Authors: Mahendra Gilang , Sukardi Sukardi 
Published: August 2021

Alat pada tugas akhir ini disuplai dengan tegangan 5 VDC digunakan untuk mensuplay tegangan NodeMCU, motor servo dan sensor ultrasonik. NodeMCU digunakan sebagai pusat proses data yang digunakan pada tugas akhir ini, motor servo digunakan untuk membuka dan menutup pintu air. Pada saat supply di hidupkan sensor ultrasonik akan membaca ketinggian air, jika mencapai pada tinggi tertentu maka mikrokontroler NodeMCU akan mengirim status ketinggian serta siaga 1 atau 4 pada aplikasi android. Pada saat supply di hidupkan sensor ultrasonik akan membaca ketinggian air, jika mencapai pada tinggi tertentu maka mikrokontroler NodeMCU akan mengirim status ketinggian serta siaga 1 atau 4 pada aplikasi android. Saya membagi menjadi dua kondisi pada penampungan pertama yaitu ketika ketinggian air mencapai 12 cm, motor servo akan membuka 45 dan pintu terbuka setengah serta mengirimkan status Siaga 4 dan kemudian jika air sudah mencapai ambang batas yaitu ketinggian 17 cm motor servo akan membuka pintu 90atau seluruhnya maka air akan mengalir ke penampungan selanjutnya dan mengirimkan notifikasi pada Telegram yaitu Siaga 3.
Perancangan Vending Machine Menggunakan Uang Kertas Berbasis Arduino
Authors: Alkausar Vicky Mora , Husnaini Irma 
Published: August 2021

Pesatnya perkembangan teknologi pada saat ini sangat memudahkan perekonomian masyarakat khususnya dalam hal jual-beli. Kemudahan dalam melakukan jual-beli salah satu kunci untuk meningkatkan efektifitas dalam meningkatkan pendapatan bagi masyarakat. Vending machine adalah salah satu alat yang dibutuhkan untuk membantu memudahkan perekonomian bagi masyarakat dalam hal jual-beli. Tulisan ini bertujuan merancang sebuah vending machine yang bekerja berdasarkan pendeteksian uang yang dimasukkan . Alat ini menggunakan TCS 3200-DB sebagai sensor untuk mendeteksi uang dan menggunakan arduino sebagai pusat kontrol serta pemroses data. Pada saat uang sudah terbaca oleh sensor TCS 3200-DB, maka LCD akan menampilkan nominal uang yang masuk. Setelah jumlah uang mencapai total Rp. 5000,- maka servo akan aktif dengan membuka katup besi yang di rancang khusus untuk mengeluarkan minuman yang sudah di pilih. Hasil pengujian alat Vending Machine ini menujukkan bahwa alat ini sudah bekerja sesuai dengan rancangan yang diinginkan, dimana alat bekerja dengan baik dan mampu mengenali uang kertas Rp. 1000, 2000 dan 5000,- dengan tingkat keberhasilan 86.6%.
The Analyses of Possible Indicators of Children With Autism Spectrum Disorders Early Diagnosis
Authors: Kharatyan Kristina 
Published: August 2021

Nowadays autism spectrum disorders (ASD) are on the list of most frequent childish disorders. It is characterized by communicational, behavioural, and emotional difficulties, unique manifestations of cognitive processes, lack of communicational initiative. ASD is a developmental disorder that occurs in early childhood, persists into adulthood, and affects three areas of development: communication, social partnership, and behavior.
So, when the means of communication are incomplete or absent, the normal course of the child's development is being disrupted, social adaptation becomes impossible. For the effective organization of speech therapy intervention of children, it is necessary to start child`s rehabilitation work as possible of the child's development:
The author's long time professional experience (15 years) in working with these children indicates that one of the keys to the best effectiveness of communication and speech development is early intervention, which can be organized only after the early detection and diagnosis of children with ASD.
One of the prerequisites for early diagnosis is to ensure the continuity of the awareness process among parents, which is the main goal of our article.
Parents Experience in Giving Sex Education to Adolescents in North Kuta
Authors: Sanjiwani Ida Arimurti , Pramitaresthi I Gusti Ayu 
Published: August 2021

Sexual education is an important think that parents can do to prevent free sex and it effects in adolescent. It is possible because family is the first place of education, but it appears to be inadequately practiced in Indonesia. This study aims to determine parent experience to provide sexual education in adolescents. We used a phenomenology interpretative approach in this study. We collected the data through in-depth interviews with ten parents. We found five themes: (1) good perception about sexual education, (2) sexual education delivered assisted by social media, (3) the topic is free sex, (4) difficult to start because of taboo and shame, (5) need support from health worker. The study reveals that sexual education is limited and need to be increased. It is essential that Indonesian parents become better informed and skilled, so that they may be involved in the sexual education of adolescent start from their family.
Index Terms— sexual education, adolescent, parents experience
Faktor-Faktor yang Memengaruhi Kompetensi Penyuluh Narkoba dalam Penyuluhan Digital
Authors: Rizal Afib , Fatchiya Anna , Sadono Dwi 
Published: August 2021

Utilization of digital media for an extension is a solution the improvement of the competence of Anti-Narcotics extension agents. This study aims to analyze the influence of the individual characteristics of the extension agents, patterns of digital media use, institutional support, and characteristics of innovation on the competence of Anti-Narcotics extension agents. This research was conducted in October 2020 - January 2021 through a census of 170 (98%) functional officers of Anti-Narcotics extension agents throughout Indonesia who have worked for approximately two years. The research instruments were questions, statements (telephone and message), and interviews which were conducted using the digital application Google Form and WhatsApp. Data were processed using Partial Least Square. The results showed that the use of digital media by extension agents consisting of patterns of digital media use, characteristics of innovation, institutional support, and competence of Anti-Narcotics extension agents in the field of information and communication technology were in the Medium category. The competence of Anti-Narcotics extension agents in the use of digital media was in the medium category. This competence is influenced by factors of digital media utilization patterns, innovation characteristics, and institutional support.
Optimizing international neurosurgical outreach missions: 15-year appraisal of operative skill transfer in Lima, Peru
Authors: Jandial Rahul , Narang Pranay , Brun Jorge Daniel , Levy Michael L. 
Published: August 2021

Background:
While several medical outreach models have been designed and executed to alleviate the unmet need for international neurosurgical care, disparate strategies have evolved. There is a need to determine the optimal pediatric neurosurgical outreach model through which resources are efficiently utilized while imparting the largest possible impact on global health. This study evaluates the efficacy of an international pediatric neurosurgery outreach model at transferring operative skill in a sustainable and scalable manner in Lima, Peru over a 15-year duration.

Methods:
Three 1-week neurosurgical missions were carried out (2004–2006) in Lima, Peru to teach neuroendoscopic techniques and to provide equipment to host neurosurgeons, equipping the hosts to provide care to indigent citizens beyond the duration of the missions. Follow-up data were obtained over a 15 year span, with collaboration maintained over email, two in-person visits, and video-conferencing services.

Results:
Since the outreach missions in 2004–2006, the host neurosurgeons demonstrated sustainability of the neuroendoscopic instruction by independently performing neuroendoscopic operations on a growing caseload: at baseline, 0 cases were performed in 2003, but since 2012 and onwards, 40–45 cases have been performed annually. Scalability is illustrated by the fact that the institution established a rigorous neuroendoscopy training program to independently pass on the techniques to resident physicians.

Conclusion:
The described international pediatric neurosurgical outreach model, centered around teaching operative technique as opposed to solely providing care to citizens, allowed operative skill to be sustainably transferred to surgeons in Lima, Peru. Having served the neuroendoscopic needs of hundreds of citizens, the strategic design is replicable and should be mirrored by future medical endeavors seeking to substantially impact the deficit in global surgical care.
Application Strategy of Mechatronics in Mechanical Design and Manufacturing
Authors: Lin Zhe , Fang Rongqing 
Published: August 2021

Industry is an pillar sector for our country's social and economic development. The development of industry is closely related to our country's economic development and social construction. The application of mechatronics in mechanical design and manufacturing can not only improve the level of mechanical design and manufacturing as well as production efficiency, but also can contribute to the further development of the mechanical design and manufacturing industry. The author investigated and analyzed advantages of the mechatronics’s application in mechanical design and manufacturing, and put forward an effective strategy of applying mechatronics in mechanical design and manufacturing, hoping to help strengthen the comprehensive strength of the mechanical design and manufacturing industry.
Overview on the Blockchain-Based Supply Chain Systematics and Their Scalability Tools
Authors: Hellani Houssein , Sliman Layth , Samhat Abed Ellatif , Exposito Ernesto 
Published: August 2021

Modern IT technologies shaped the shift in economic models with many advantages on cost, optimization, and time to market. This economic shift has increased the need for transparency and traceability in supply chain platforms to achieve trust among partners. Distributed ledger technology (DLT) is proposed to enable supply chains systems with trust requirements. In this paper, we investigate the existing DLT-based supply chain projects to show their technical part and limitations and extract the tools and techniques used to avoid the DLT scalability issue. We then set the requirements for a typical DLT-based supply chain in this context. The analyses are based on the scalability metrics such as computing, data storage, and transaction fees that fit the typical supply chain system. This paper highlights the effects of Blockchain techniques on scalability and their incorporation in supply chains systems. It also presents other existing solutions that can be applied to the supply chain. The investigation shows the necessity of having such tools in supply chains and developing them to achieve an efficient and scalable system. The paper calls for further scalability enhancements throughout introducing new tools and/or reutilize the current ones. Doi: 10.28991/esj-2021-SP1-04 Full Text: PDF
Persepsi Dokter Hewan Praktisi Hewan Kecil terhadap Telemedicine di Masa Pandemi Covid-19
Authors: Aulia Muhammad Fadly , Budinuryanto Dwi Cipto , Wismandanu Okta 
Published: August 2021

Telemedicine is defined as remote diagnose and patient care using telecommunications technology. Recently telemedicine technology was introduced to the field of veterinary medicine. Due to the nature of telecommunications, a veterinarian will utilize telemedicine technology as a means of assessing patient severity and providing medical advice. The perception of veterinarians, especially small animal practitioners, to telemedicine is influenced by many factors, for example: age, desire (expectation), attention (focus), information obtained, and other factors. This study aims to determine the factors that influence veterinarians' perceptions of telemedicine. This research is expected to be an input in implementing telemedicine in practice. The design of this study is descriptive method, where the sampling method uses a questionnaire filled out by small animal practitioners online. The results showed that the pandemic had no impact on veterinary services. But there is an adaptation of practice procedure. Respondents are neutral towards the application of telemedicine, but the majority of respondents who have implemented telemedicine think that the application of telemedicine has a good impact on health services. There are many obstacles felt by respondents in implementing telemedicine.