bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Ethnographer from Within: Wild Thought in Stefano D’Arrigo’s Horcynus Orca
Authors: Caradonna Chiara 
Published: June 2021

Abstract
The present article aims to demonstrate how ethnography is present, discussed, and criticized in Stefano D’Arrigo’s novel Horcynus Orca (1975). Through a comparison with a passage from Claude Lévi-Strauss’s Tristes Tropiques (1955), the novel is shown to adopt and challenge central tenets of ethnography. D’Arrigo imagines the possibility of an ‘ethnographer from within,’ a member of a Sicilian fishermen community who, by virtue of his personal experience, possesses the necessary distance to report about his community of origin, yet cannot help but impact it significantly as he in turn brings along and into the community a different system of thought. The article exposes the multiple inversions and subversions that the novel operates with respect to the dichotomic pairs nature/culture, civilized/primitive, indigenous/foreign, as well as to ethnography itself by focussing on the occurrence of ethnographic documents in key passages of the novel. Lévi-Strauss’s Tristes Tropiques and possibly to an even greater extent Horcynus Orca are concerned with the contradictions inherent in the study of humankind, its various manifestations, and its position in the world, without aspiring to resolve them in any univocal or definitive way.
Zur Frage der Provenienz
Authors: Giuliani Luca 
Published: June 2021

Abstract
The question of provenance can have very different implications in different disciplines. In the case of archaeological objects, the finding spot of an object provides us with information about the objectʼs original meaning and function. If the excavation is illegal, those involved in illicit antiquities tend to cancel any trace of their action that could be used as proof of the crime. This leads to a systematic destruction of information: when the objects appear on the market they seem to come out of nowhere; it is exactly this loss of contextual information (and not the problem of ownership) that makes illegal excavation intolerable from a scholarly perspective. My test case is a Greek archaic statue acquired by the Berlin Museum in 1925: it had been heavily damaged in order to facilitate its smuggling out of Greece and then carefully restored in order to promote its acquisition by the museum.
„Alles ist in Gott“ – Überlegungen zur bestimmenden theologischen Denkform desCorpus Hermeticum
Authors: Krämer Benedikt 
Published: June 2021

AbstractGiven theCorpus Hermeticum’s history of formation, it has prompted the attempt to separate layers or groups of writings within the collection of treatises. This process of division, which was for the most part undertaken on criteria of content (dualism, pantheism, etc.), has been viewed rather negatively by the more recent research, on grounds of method. Given the discovery of numerous doctrinal contents that remain constant across different treatises, increased efforts are being made to reconstruct theCorpus’s moments of unity. The present paper aims, in this spirit, to provide a more precise identification of the overarching forms of theological thought in the Hermetic writings. The reflections that follow aim to make it plausible that the defining form of theological thought in theCorpus Hermeticumcan be classified as panentheism. In addition, the distinctive form of this influential theological paradigm in the Hermetic writings will be considered.
Bemerkungen zurEktheosis Arsinoesdes Kallimachos: Gattung, Struktur und Inhalt
Authors: Adorjáni Zsolt 
Published: June 2021

AbstractThis article aims to present an overall interpretation of a poem by Callimachus that centres on the dead Ptolemaic queen Arsinoe II. Firstly the position of theEktheosis Arsinoesin Callimachus’ œuvre, the genre to which it belongs and its structure will be investigated. This leads to the analysis of the highly allusive character of the work (above all to Hesiod, Ibycus, Simonides and Pindar as well as to hymnic poetry). In addition, realia (the historical background) and textual difficulties arising from the fragmentary transmisson will also be treated. The appendix discusses a hitherto unnoticed testimony to the poem’s reception in the Roman epicist Ennius.
Arms-bearers in separate graves from Great Moravia and the emergence of the Early Medieval military-aristocratic organization in East-Central Europe
Authors: Macháček Jiří , Berner Margit , Dresler Petr , Kaupová Sylva Drtikolová , Přichystalová Renáta , Sládek Vladimír 
Published: June 2021

Abstract
Die Existenz Großmährens wird in die Zeit vom 9. bis zur 1. Hälfte des 10. Jahrhunderts datiert. Es erstreckte sich zwischen dem karolingischen Westen und dem slawischen „Außeneuropa“ und galt als erstes Staatsgebilde der Slawen, das die militär-aristokratische Struktur Westeuropas nachahmte. Neu entdeckte separate Bestattungen mit Waffen und Sporen lassen jedoch Zweifel an dieser Deutung aufkommen. Der besondere Bestattungsritus der hier vorgelegten Bestattungen weist zwar Ähnlichkeiten mit den separaten Friedhöfen des fränkischen grundherrschaftlichen Adels oder der freien Bauernkrieger auf, die archäologischen und bioarchäologischen Analysen erlauben in Mähren jedoch Rückschlüsse auf ein unterschiedliches soziales Phänomen, das zur Erschließung der historischen und kulturellen Spezifika dieses Raums als Schnittstelle zwischen Ost und West beitragen könnte.
The tradition of pottery painting in the Upper Silesian-Lesser Polish regional group of the Lusatian culture in the Early Iron Age. The example of the cemetery at Dobrzeń Mały, Opole district.
Authors: Markiewicz Małgorzata , Tomczak Eugeniusz 
Published: June 2021

Abstract
The idea of covering pottery with polychrome ornaments adopted from the Greek art of the Late Geometric period spread to almost every corner of Early Iron Age Europe, including some areas in present-day Poland. Painted pottery was manufactured in Middle Silesia and southern Greater Poland. Finds of painted vessels are recorded also in Upper Silesia, and a smaller number still, in Lesser Poland. The presented paper addresses painted pottery identified with the Upper Silesian-Lesser Polish regional group of the Lusatian culture from settlement and funerary contexts (cremation and bi-ritual cemeteries). A closer look is taken at the previously unpublished finds of polychrome vessels from the cemetery at Dobrzeń Mały investigated during the 1970s. Their collection is now displayed and preserved in the Museum of Opole Silesia in Opole.
War and Order in Eighteenth Dynasty Egypt (1550‒1295 BCE)
Authors: Allon Niv 
Published: June 2021

Summary
This paper studies royal inscriptions of the Eighteenth Dynasty—a period of extensive military activity in Nubia and the Levant—to examine the prevailing assumption that earthly wars were conceived as mirroring a cosmic struggle between order and chaos. Instead, the sources suggest a more intricate picture, in which royal prerogative and divine will are at play, often ambiguously intertwined.
Remarks on the Orthography of Word rm
ṯ in the Old Kingdom
Authors: El-Sattar Ibrahim Abd 
Published: June 2021

Summary
This paper investigates the orthographies of the word rmṯ in the Old Kingdom and the factors impacting them. It is based on a survey of texts that include this word. It aims to identify features of spelling originality and means of dissemination of orthographical forms. The study also urged with its pronunciation, its plurality and singularity, the nature and significance of its determinatives. Finally, the study concluded that there is an obvious orthography-system of this word which could be geographically, and chronology traced.
Classification Strategies from the End of the Ramesside Period until the Late Period: a Living System
Authors: Chantrain Gaelle 
Published: June 2021

Summary
This study is part of a diptych. It is conceived as a general theoretical introduction to a forthcoming substantial case study describing the economy of the classifiers system in the Late Period tomb of Menekhibnekau in Abusir. In the first part of the present paper, I shall first go through an overview of the functioning of the classifier system and some suggestions about its evolutive dynamics in diachrony. In the second part, I will introduce five classification strategies that can be encountered in the texts from the end of the Ramesside period down to the Late Period. These strategies will be explained and illustrated by means of two case studies: the manuscript L of the Teaching of
Amenemope and the texts from the tomb of Menekhibnekau.
ORP2 couples LDL‐cholesterol transport to FAK activation by endosomal cholesterol/PI(4,5)P2 exchange
Authors: Takahashi Kohta , Kanerva Kristiina , Vanharanta Lauri , Almeida‐Souza Leonardo , Lietha Daniel , Olkkonen Vesa M , Ikonen Elina 
Published: June 2021

AbstractLow‐density lipoprotein (LDL)‐cholesterol delivery from late endosomes to the plasma membrane regulates focal adhesion dynamics and cell migration, but the mechanisms controlling it are poorly characterized. Here, we employed auxin‐inducible rapid degradation of oxysterol‐binding protein‐related protein 2 (ORP2/OSBPL2) to show that endogenous ORP2 mediates the transfer of LDL‐derived cholesterol from late endosomes to focal adhesion kinase (FAK)‐/integrin‐positive recycling endosomes in human cells. In vitro, cholesterol enhances membrane association of FAK to PI(4,5)P2‐containing lipid bilayers. In cells, ORP2 stimulates FAK activation and PI(4,5)P2 generation in endomembranes, enhancing cell adhesion. Moreover, ORP2 increases PI(4,5)P2 in NPC1‐containing late endosomes in a FAK‐dependent manner, controlling their tubulovesicular trafficking. Together, these results provide evidence that ORP2 controls FAK activation and LDL‐cholesterol plasma membrane delivery by promoting bidirectional cholesterol/PI(4,5)P2 exchange between late and recycling endosomes.
Rhabdomyolysis-induced acute kidney injury in a patient with non-compliance to levothyroxine therapy
Authors: Ghayur Ayesha , Elahi Qurrat , Patel Chinmay , Raj Rishi 
Published: June 2021

Summary
Hypothyroidism is a common medical condition and is often easily managed with excellent outcomes, when treated adequately. Compliance with levothyroxine (LT4) therapy is often compromised because of the need for a daily and lasting schedule. Overt rhabdomyolysis due to under-treatment or non-compliance is a rare occurrence. We report a case of rhabdomyolysis leading to acute kidney injury (AKI) on chronic kidney disease (CKD) requiring hemodialysis (HD) in a 68-year-old Caucasian male due to non-compliance with levothyroxine (LT4) therapy. Our patient 'ran out of levothyroxine' for approximately 4 weeks and developed gradually progressive muscle pain. The diagnosis of severe AKI due to rhabdomyolysis was made based on oliguria, elevated creatinine kinase (CK), and renal failure. Resuming the home dose of LT4 failed to correct CK levels, and there was a progressive decline in renal function. Although increasing doses of LT4 and three cycles of HD improved CK levels, they remained above baseline at the time of discharge. The patient recovered gradually and required HD for 4 weeks. CK levels normalized at 6 weeks. Through this case report, we highlight that non-compliance with LT4 therapy can lead to life-threatening complications such as renal failure and hence the need to educate patients on the significance of compliance with LT4 therapy should be addressed.

Learning points

Non-compliance to levothyroxine therapy is common and can lead to serious complications, including rhabdomyolysis.

Rhabdomyolysis is an uncommon presentation of hypothyroidism and severe rhabdomyolysis can result in renal failure requiring hemodialysis.

Rhabdomyolysis associated with hypothyroidism can be further exacerbated by concomitant use of statins.
IGF1 haploinsufficiency in children with short stature: a case series
Authors: Staels Willem , Alev Nuriya , Maystadt Isabelle , Chivu Olimpia , De Schepper Jean , Heinrichs Claudine , Beckers Dominique 
Published: June 2021

Context:
Short stature in children is a common reason for referral to pediatric endocrinologists. The underlying cause of short stature remains unclear in many cases and patients often receive unsatisfactory, descriptive diagnoses. While textbooks underline the rarity of genetic causes of growth hormone (GH) insensitivity and the severity of its associated growth failure, increased genetic testing in patients with short stature of unclear origin has revealed gene defects in the GH/insulin-like growth factor (IGF-I) axis associated with milder phenotypes. As such, heterozygous IGF1 gene defects have been reported as a cause of mild and severe short stature. Here, we aimed to describe the clinical and hormonal profile of children with IGF1 haploinsufficiency and their short-term response to growth hormone treatment (GHT).

Case descriptions:
We describe five patients presenting with short stature, microcephaly, and in four out of five born small for gestational age diagnosed with IGF1 haploinsufficiency. The phenotype of these patients resembles that of previously described cases with similar gene defects. In our series, segregation of the short stature with the IGF1 deletion is evident from the pedigrees and our data suggests a modest response to GHT.

Conclusions:
This study is the first case series of complete heterozygous IGF1 deletions in children. The specific genetic defects provide a clear image of the phenotype of IGF1 haploinsufficiency – unbiased by heterozygous mutations with possible dominant negative effects on IGF-I function. We increase the evidence for IGF1 haploinsufficiency as a cause of short stature, microcephaly, and SGA.
Trends and Factors Related to Blunt Use in Middle and High School Students, 2010–2020
Authors: Ebrahimi Kalan Mohammad , Jebai Rime , Bursac Zoran , Popova Lucy , Gautam Prem , Li Wei , Alqahtani Mohammed M. , Taskin Tanjila , Atwell Leah L. , Richards Jennifer , Ward Kenneth D. , Behaleh Raed , Ben Taleb Ziyad 
Published: June 2021

BACKGROUND AND OBJECTIVES
Blunt use is a popular mode of marijuana consumption among adolescents in the United States, but little is known about how its prevalence has changed over time or factors associated with its use. With this study, we assessed trends and correlates of past (ever used but not in the past 30 days) and current (used in past 30 days) blunt use among adolescents in Florida.

METHODS
We analyzed data from 2010–2020 cross-sectional, statewide representative Florida Youth Tobacco Surveys that comprised 461 706 middle and high schoolers using Joinpoint to calculate annual percentage change (APC) in the weighted prevalence of past and current blunt use. A weighted multivariable regression model was developed by using 2019–2020 Florida Youth Tobacco Survey data to examine the factors associated with past and current blunt use.

RESULTS
Whereas the prevalence of past (APC = −5.32%) and current (APC = −5.28%) blunt use significantly decreased from 2010 to 2015, an increasing trend in current use prevalence (APC = 14.91%) was observed from 2015 to 2018 and has been approximately constant ever since. Similar increasing trends were observed in current blunt use among female students (APC = 14.92%), middle schoolers (19.57%), and non-Hispanic (NH) white students (APC = 11.12%) from 2016 to 2020. Several factors were consistently associated with greater odds of both past and current blunt use for both middle and high schoolers, including older age, being NH Black (versus NH white), past and current use of cigarettes, electronic cigarettes, hookah, cigars, and ever vaping marijuana.

CONCLUSIONS
Although blunt use among Florida youth decreased from 2010 to 2015, substantial increases were observed since 2015, suggesting that existing tobacco control programs should incorporate marijuana (and blunt) modules into existing tobacco and nicotine prevention programs.
Struktur dan Kultur Budaya dalam Keluarga di Era Adaptasi Kebiasaan Baru (AKB) di Lingkungan Keluarga Kota Bandung
Authors: Azizah Nur 
Published: June 2021

Abstrak: Virus corona yang terjadi saat ini merupakan serangan yang dahsyat yang mempengaruhi kondisi pada kesehatan yang ada pada manusia dan proses penularan yang begitu menyebar dengan cepat. Oleh karena dahsyatnya pandemi Covid 19 itu, perlawanannya pun mengedepankan kekuatan kesehatan sebagai panglima. Tujuan penelitian ini adalah untuk menganalisis : (a) Era AKB (Adaptasi Kebiasaan Baru) pada transisi pandemi memberikan perubahan dari struktur dan kultur budaya dalam keluarga, (b) Mengeksplorasi aspek-aspek kultur budaya dalam Keluarga di masa Era AKB (Adaptasi Kebiasaan Baru), (c) Menganalisis tantangan, harapan, dan Pengendalian diri dalam menghadapi perubahan di Era AKB (Adaptasi Kebiasaan Baru) di Lingkungan keluarga Kota Bandung. Metode penelitian yang dilakukan melalui hasil observasi kepada partisipan, melakukan analisis data dan laporan, proses wawancara, dan menggunakan Diskusi Group. Merode Penelitian etnografis dilakukan melalui berbagai tahapan dan proses penelitian secara kualitatif dan bersifat induktif. Penelitian menemukan 4 hal pokok yaitu; (a) Era AKB (Adaptasi Kebiasaan Baru) tidak merubah struktur namun merubah kultur budaya dalam keluarga dari segi kedisplinan diri merubah; (b) Peran Keluarga dalam memberikan motivasi kepedulian menjaga kesehatan yang paling terdekat (c) penguatan kesadaran atas tradisi budaya masyarakat khususnya di lingkungan keluarga Kota Bandung dengan penerapan Penggunaan Masker makin dimengerti dan bermanfaat menjaga diri dalam menghadapi sentuhan COVID-19. (d) Nilai-Nilai Positif di Era AKB (Adaptasi Kebiasaan Baru). (1) Semua Anggota Keluarga terbentuk melakukan kampanye menjaga kebersihan dan kesehatan di dalam kehidupan sehari-hari. (2) Melahirkan kebudayaan baru secara global dalam pemahaman secara teknologi.
Optimization of bronchial asthma treatment according to polymorphism in the leukotriene-C4 synthase gene
Authors: Cherednichenko Nataliia , Kochuieva Maryna , Tymchenko Hanna , Zaikina Yulia , Kochuiev Gennadii , Liashok Andrii 
Published: June 2021

The aim of the study was to investigate the effectiveness of different schemes of basic asthma therapy depending on the polymorphism of the LTC4 gene.
Materials and methods. 181 patients with asthma were recruited to participate in the study. All patients included in the study underwent a general clinical study, spirometry, the level of asthma control was determined by Asthma control questionnaire 5 (ACQ-5), by studying the polymorphism of the LTC4 gene, it was determined that patients belong to the A/A, A/C and C/C genotypes.
Results. Allelic -444C polymorphism of the LTC4-S gene (rs 730012) had the following genotype frequency among asthma patients: A/A – 77 people (42.6 %), A/C – 73 people (40.3 %) and C/C – 31 people (17.1 %).
In groups of patients with genotypes A/A and A/C, during treatment with a low dose of ICS and montelukast, there was a significant improvement in FEV1 and the score according to the ACQ-5 questionnaire (asthma control level). However, in the group of patients with the C/C genotype, there were no significant changes in FEV1 and the score according to the ACQ-5 questionnaire.
In the groups of patients with genotypes A/A and C/C on the background of increasing the dose of ICS to medium in a fixed combination with LABA compared with the results of treatment with low-dose ICS and montelukast, there was a significant improvement in FEV1 and asthma control – ACQ- 5. At the same time, in the group of patients with genotype A/C, there were no reliable indicators of FEV1 and ACQ-5 score changes.
Conclusions. The frequency of genotypes A/A, A/C and C/C for LTC4S polymorphism in the studied population are 42.6 %, 40.3 % and 17.1 %, respectively.
Patients with genotypes A/A and C/C have a significant response to treatment with a low dose of ICS and montelukast in the form of an improvement in FEV1 and ACQ-5 score.
Increasing the dose of ICS up to moderate in a fixed combination with β2-LABA in groups of patients with genotypes A/A and C/C leads to a significant improvement in the FEV1, as well as in the asthma control level - ACQ-5
Morphological manifestations of experimental paclitaxel-induced sciatic neuropathy under correction of 2-ethyl-6-methyl-3-hydroxypyridine succinate
Authors: Ostrovskyi Mykola 
Published: June 2021

Paclitaxel is an effective chemotherapeutic agent for many cancers, but it has a number of limiting side effects that not only significantly reduce the quality of life of patients, but also limit their further treatment. Peripheral neuropathy is one of these, but there are currently no proven effective druHS for the prevention or treatment of paclitaxel-induced neuropathic pain (PINP) in particular, or chemotherapy-induced peripheral neuropathy (CIPN) in general. 2-ethyl-6-methyl-3-hydroxypyridine succinate (HS) is a derivative of succinic acid with neuroprotective, antihypoxic, membrane-protective, nootropic, sedative effects.
The aim of the study was to study the effect of the neuroprotective agent HS on the pathomorphogenesis of the sciatic nerves under conditions of paclitaxel-induced peripheral neuropathy in the experiment.
Materials and methods. The experiment was carried out on 80 white rats, which were injected intraperitoneally with paclitaxel (Actavis, Romania), previously dissolved in isotonic saline at a dose of 2 mg / kg of body weight four times every other day until a total dose of 8 mg / kg was reached. Then forty of these animals were injected intraperitoneally with 2-ethyl-6-methyl-3-hydroxypyridine succinate at a dose of 10 mg / kg (the remaining 40 rats received intraperitoneal water for injection). Morphological studies were carried out on the first, seventh, fifteenth, twenty-eighth, sixtieth, ninetieth and one hundred and twentieth days after the last injection of the drug. We investigated the pharmacological potential of HS in the prevention and treatment of CIPN at the level of sciatic nerve (SN) morphology.
Results. The maximum value of the average profile area of myelinated nerve fibers with the use of HS is significantly lower than with uncorrected flow, and is (78.12±2.24) μm2 compared to (94.04±1.03) μm2 (p <0.001). The introduction of HS provides a stable content of the value of the ratio of the areas of the axial cylinder and the fiber within 0.39±0.01 (first day) - 0.44±0.01 (ninetieth day), and a rapid recovery of the indicator value to normal values during the final 30 days of the experiment. the maximum value of the index of the profile area of the myelin sheath with the introduction of HS is 1.4 times less than with an uncorrected flow, and is, respectively, (49.01±1.59) μm2 and (69.77±1.87) μm2 (p <0.001). HS provides a more intensive restoration of the indicator of the area of the myelin sheath during the 90th - 120th day of the experiment.
Conclusions. Our results allow us to conclude that the introduction of HS creates a protective effect against paclitaxel-induced peripheral neuropathy (PIPN) by acting on both the axial cylinder and the myelin sheath of the heart failure. Due to the known pathophysiological mechanisms of the development of neuropathy, this method can be a promising therapeutic agent for the prevention and treatment of PIPN