bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dual response of osteoblast activity and antibacterial properties of polarized strontium substituted hydroxyapatite—Barium strontium titanate composites with controlled strontium substitution
Authors: Swain Subhasmita , Bowen Chris , Rautray Tapash 
Published: April 2021

AbstractTo mimic the electrical properties of natural bone, controlled strontium substitution of both hydroxyapatite and ferroelectric barium titanate were achieved by mixing in the ratio 30:70 by weight. The composites were characterized by X‐ray diffraction, Fourier transform infrared spectroscopy and scanning electron microscopy to investigate the phase composition and microstructure of the composites. Unpolarized and polarized strontium hydroxyapatite (SrHA)‐barium strontium titanate (BST) composites with controlled degree of Sr substitution were examined, including 5SrHA‐5BST (5% Sr substitution in both components) and 10SrHA‐10BST composites. The 10SrHA‐10BST composite showed a higher osteoblast activity, as observed from the cell viability studies performed using CCK‐8 assay. The polarized composites showed promise against Staphylococcus aureus bacteria by minimizing the adhesion and growth of bacteria, as compared with their unpolarized counterparts. The polarized 10SrHA‐10BST was found to be superior than all other composites. As a result, the approach of polarization of SrHA‐BST composites has been found to be an effective bone substitute material in controlled enhancement of osteoblast growth with simultaneous reduction of bacterial infection.
Acknowledging Intersectional Identity in Supervision: The Multicultural Integrated Supervision Model
Authors: Mitchell Michelle D. , Butler S. Kent 
Published: April 2021

Supervision is considered a critical component in the development of mental health professionals. Thus, to ensure ethical services are provided to clients, supervisors should integrate multicultural perspectives within supervision. Multicultural and social justice principles, although present in the literature, have not been successfully incorporated into previous process and developmental models as viable enhancers to practitioner growth. The multicultural integrated supervision model presented in this article provides supervisees, supervisors, and counselor educators with methods that elicit deeper appreciation for culturally appropriate relationships and interactions.La supervisión se considera un componente crítico de la capacitación de profesionales en la salud mental. Por lo tanto, para garantizar que se proporcionan servicios éticos a los clientes, los supervisores deberían integrar perspectivas multiculturales en la supervisión. Los principios multiculturales y de justicia social, aunque se encuentran en la literatura, no se han incorporado con éxito en los modelos anteriores de procesos y desarrollo como potenciadores viables del crecimiento profesional de los consejeros. El modelo de supervisión multicultural integrada que se presenta en este artículo proporciona a los supervisados, supervisores y educadores de consejeros unos métodos que suscitan una apreciación más profunda por las relaciones e interacciones culturalmente apropiadas.
Change in the local impedance and electrograms recorded by a micro‐electrode tip catheter during initial atrial fibrillation ablation
Authors: Hashimoto Kenji , Tsuzuki Ippei , Seki Yuta , Ibe Susumu , Yamashita Terumasa , Miyama Hiroshi , Fujisawa Taishi , Katsumata Yoshinori , Kimura Takehiro , Fukuda Keiichi , Takatsuki Seiji 
Published: April 2021

AbstractBackgroundA novel measurement of the local impedance (LI) and electrograms recorded from micro‐electrodes on catheter tip has been developed. However, the data during pulmonary vein (PV) ablation is not sufficient. We aimed to investigate the utility of this measurement during initial atrial fibrillation (AF) ablation.MethodsWe investigated 111 representative radiofrequency applications in 7 AF patients without a history of prior ablation (6 males, age 68 [65‐72] years, 2 persistent AF). The ablation strategy was PV isolation for paroxysmal AF and single ring box isolation for persistent AF, using MiFi catheter. The correlation of the generator impedance (GI) drop and LI drop after radiofrequency applications and the predictive value of the initial LI elevation before radiofrequency applications for LI drop were analyzed. Also, the LI and GI drop were investigated according to the location of RF applications.ResultsThe LI drop was higher than GI drop (23.7 [16.4‐35.7] and 9.0 [6.0‐12.0]; P < .01). There were correlations between the initial LI elevation and LI drop (R2 = 0.466, P < .01) and between the LI and GI drop (R2 = 0.263, P < .01). The LI drops significantly differed according to the different anatomical localizations by the Kruskal–Wallis test, although the GI drops did not differ (P < .01 and P = .49, respectively)ConclusionLI drop was associated with initial LI elevation and was larger than GI drop. LI drop was different according to locations, although GI drop was not. These findings might indicate that LI drop would be a more sensitive marker for lesion formation than GI drop.
Detection and verification of tropical cyclones and depressions over the South Pacific Ocean basin usingERA‐5 reanalysis dataset
Authors: Yeasmin Alea , Chand Savin , Turville Christopher , Sultanova Nargiz 
Published: April 2021

AbstractTropical cyclones (TCs) are one of the most destructive synoptic systems and can cause enormous loss of life and property damages in the South Pacific island nations. The impact of tropical depressions (TDs, i.e. weaker systems that do not develop into TCs) can also be staggering in the region in terms of heavy flooding and landslides, but a lack of complete records often hinders research involving TD impacts. A methodology has been developed here to detect TDs in the ERA‐5 reanalysis dataset (the fifth generation ECMWF atmospheric reanalysis of the global climate) using the Okubo–Weiss–Zeta parameter (OWZP) detection scheme. The new South Pacific Enhanced Archive for Tropical Cyclones dataset (SPEArTC), the Dvorak analysis of satellite‐based cloud patterns over the South Pacific Ocean basin, and a rainfall dataset for various stations and historical archives have been utilized to validate ERA5‐derived TCs and TDs for the period between 1979 and 2019. Results indicate that the OWZP method shows substantial skill in capturing the realistic climatological distribution of TDs (as well as TCs) for the South Pacific Ocean in the ERA5 reanalysis, paving a way forward for future climatological studies involving the impacts of TCs and TDs over the island nations using longer‐term reanalyses products such as the 20th‐century reanalysis dataset that extends back to the 1850s.
The impact of perceived ethical climate types on workplace deviance: An empirical investigation of IT professionals in India
Authors: Ramadugu Hiranmayakaparthi , Rastogi Renu 
Published: April 2021

AbstractThe costs of deviant behavior in the workplace can go far beyond direct financial losses, and may result in lost business opportunities, damage to the brand, and the loss of market position. However, there has been little research into the influence of ethical climate types on workplace deviance. India's IT industry now makes a substantial contribution to the country's GDP, exports, and employment; hence, the goal of this study is to explore the impact of perceived ethical climate types on workplace deviance in the Indian IT industry. Using data from a survey of 158 IT professionals working in Hyderabad, India, the study presents an analysis of workplace deviance using four ethical climate types, principled, benevolent, efficiency oriented, and profit oriented. The study shows that principled and benevolent climate types have a significant negative association with workplace deviance, while efficiency and profit‐oriented climate types have a significant positive association. The results support the idea that perceived ethical climate types can be leveraged to help contain the threat of deviant behavior in the workplace.
Research on Industry 4.0 and on key related technologies in Vietnam: A bibliometric analysis using Scopus
Authors: Pham‐Duc Binh , Tran Trung , Le Hien‐Thu‐Thi , Nguyen Nhi‐Thi , Cao Ha‐Thi , Nguyen Tien‐Trung 
Published: April 2021

AbstractBibliometric analysis was performed to study the development of publications related to Industry 4.0 and its key technologies in Vietnam. Comparisons with data from other ASEAN countries, and with global data have been done to identify distinctive characteristics of Industry 4.0 literature from Vietnam. The collection of 1,470 retrieved papers was analysed to answer seven research questions. Our results highlighted some valuable insights of Industry 4.0 literature in Vietnam. The number of papers in Industry 4.0 in Vietnam increased rapidly in recent years, mostly focused on Computer Science, Engineering, and Mathematics. Iran, China, and South Korea were the most productive partner countries with Vietnam in Industry 4.0. Machine learning, artificial intelligence, big data, deep learning, Internet of things, neural networks, and data mining were among the most popular research themes in Industry 4.0 in Vietnam. Vietnam ranked third among 10 Southeast Asian countries, based on the number of published papers in Industry 4.0, but the gap with the two top countries was large. Compared to the global data, the annual growth rate of Industry 4.0 papers in Vietnam, and other Southeast Asian countries was lower. Findings from this work can be helpful for other scholars in establishing potential future research lines related to Industry 4.0 in Vietnam.
The importance of jellyfish–microbe interactions for biogeochemical cycles in the ocean
Authors: Tinta Tinkara , Klun Katja , Herndl Gerhard J. 
Published: April 2021

AbstractJellyfish blooms can represent a significant but largely overlooked source of organic matter (OM), in particular at the local and regional scale. We provide an overview of the current state of knowledge on the bloom‐forming jellyfish as sink and source of OM for microorganisms. In particularly, we compare the composition, concentration, and release rates of the OM excreted by living jellyfish with the OM stored within jellyfish biomass, which becomes available to the ocean's interior only once jellyfish decay. We discuss how these two stoichiometrically different jelly‐OM pools might influence the dynamics of microbial community and the surrounding ecosystem. We conceptualize routes of jelly‐OM in the ocean, focusing on different envisioned fates of detrital jelly‐OM. In this conceptual framework, we revise possible interactions between different jelly‐OM pools and microbes and highlight major knowledge gaps to be addressed in the future.
The impact of seasonal sulfate–methane transition zones on methane cycling in a sulfate‐enriched freshwater environment
Authors: Kleint Jan F. , Wellach Yannic , Schroll Moritz , Keppler Frank , Isenbeck‐Schröter Margot 
Published: April 2021

AbstractLake Willersinnweiher located in south‐western Germany is a small eutrophic gravel pit lake fed by sulfate‐enriched groundwater. The aim of this study was to investigate the total methane (CH4) mass balance of Lake Willersinnweiher with a particular focus on the interaction of carbon and sulfur cycling within the lake sediments and the redoxcline of the water column. Our results show that Lake Willersinnweiher permanently releases CH4 to the atmosphere throughout the whole year 2018 at rates ranging from 5 to 120 mol d−1. Sediment data show the presence of intense anaerobic oxidation of CH4 in the upper sediment layers during early summer. Here, CH4 is most likely consumed via sulfate in sulfate–methane transition zones (SMTZs) that have been observed for a few specific freshwater environments only. Seasonal dynamics in biogeochemical processes trigger the non‐steady state conditions within the sediments and the CH4 consumption in the SMTZs. In parallel, CH4 released from the sediments is completely consumed by aerobic oxidation processes in the redoxcline indicated by minimum CH4 concentrations with high δ13C–CH4 values. This zone acts as an effective barrier, minimizing CH4 release into the surface water and the atmosphere and thus CH4 oversaturation along with near‐atmospheric isotopic composition indicate the presence of an additional CH4 source in the epilimnion of Lake Willersinnweiher.
Validation of α‐Synuclein in L1CAM‐Immunocaptured Exosomes as a Biomarker for the Stratification of Parkinsonian Syndromes
Authors: Jiang Cheng , Hopfner Franziska , Berg Daniela , Hu Michele T. , Pilotto Andrea , Borroni Barbara , Davis Jason J. , Tofaris George K. 
Published: April 2021

AbstractBackgroundParkinson's disease is characterized by intraneuronal α‐synuclein aggregation. Currently there is no α‐synuclein‐based blood test in clinical practice.ObjectivesOur aim was to assess by means of further testing and analysis whether α‐synuclein measurements in serum L1CAM‐immunocaptured exosomes can differentiate Parkinson's disease from related movement disorders.MethodsWe used poly(carboxybetaine‐methacrylate)‐coated magnetic beads to isolate L1CAM‐positive exosomes and triplexed electrochemiluminescence to measure exosomal α‐synuclein, clusterin, and syntenin‐1 from 267 serum samples. Combined analysis of our current and previously published data from the Oxford, Kiel, Brescia, and PROSPECT cohorts consisting of individuals (total n = 735) with Parkinson's disease (n = 290), multiple system atrophy (MSA, n = 50), progressive supranuclear palsy (n = 116), corticobasal syndrome (n = 88), and healthy controls (n = 191) was done using 2‐stage (training vs validation) receiver operating characteristic analysis.ResultsWe established that α‐synuclein level in L1CAM‐immunocaptured exosomes above 14 pg/mL is a robust biomarker across cohorts that distinguishes Parkinson's disease from MSA (AUC, 0.90 vs 0.98) or 4‐repeat tauopathies (AUC, 0.93 vs 0.94). We confirmed that exosomal clusterin is elevated in subjects with 4‐repeat tauopathy, and when combined with α‐synuclein, it improved the performance of the assay in differentiating Parkinson's disease from 4‐repeat tauopathies to AUC, 0.98 versus 0.99. Correction for the generic exosomal protein syntenin‐1 did not consistently improve the performance of the assay.Conclusionsα‐Synuclein and clusterin in L1CAM‐immunocaptured serum exosomes is a validated blood test for the molecular stratification of neuronal α‐synucleinopathy (ie, Lewy body pathology) versus phenotypically related neurodegenerative movement disorders. © 2021 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society
Decoupling convolution network for characterizing the metastatic lymph nodes of breast cancer patients
Authors: Zeng Rutong , Zhang Xiang , Zheng Chushan , Du Jin‐Hong , Gao Zixiong , Jun Wei , Shen Jun , Lu Yao 
Published: April 2021

PurposeThe dual‐energy computed tomography (DECT) technique is an emerging imaging tool that can better characterize material features and has the potential to be a noninvasive means of predicting lymph node metastasis. The purpose of this study was to establish a DECT‐specified quantitative approach based on a neural network to characterize the sentinel lymph node (SLN).MethodsWith IRB approval, we retrospectively collected a total of 229 patients (100/229 metastasis) with biopsy proven breast cancer in this study. The chest and axillary spectral CT examinations were performed prior to the axillary lymph node (ALN) surgery. A decoupling convolution network with 11 ROIs from sequential keV (40 to 140 keV with 10 keV increment) was proposed to explicitly extract the spectral and spatial features in a DECT to predict the lymph node status. Focal loss was introduced as the loss function. The metric of the slope of the spectral Hounsfield unit curve measured at the venous phase was used as the baseline approach in comparison to our approach. In additional, a logistic model with radiomic features was also compared to our approach. The area under ROC curve (AUC) was used as the figure of merit to evaluate the classification performance.ResultsBy introducing spectral convolution and focal loss, AUC on test set could be improved by 0.15 and 0.01 separately. Compared to the slope of the spectral curve with the average AUC of 0.611 and radiomic model with AUC of 0.825, the proposed approach demonstrates a considerably better performance, with test set AUC value of 0.837, by using decoupling spectral and spatial convolution together with focal loss function.ConclusionsWe presented a new decoupling neural network based quantification method for DECT analysis, which might have potential as a noninvasive tool to predict metastasis lymph node status for breast cancer in clinical practice.
Design of a vane mixer with controlled extensional/shear strength ratio and its application for carbon fiber/polyamide 6 composites
Authors: Yin Xiaochun , Luo Jihong , Feng Yanhong , He Guangjian 
Published: April 2021

AbstractIn this work, a novel melt mixing method and its corresponding mixing device are developed. The extensional/shear strength ratio of the device can be controlled by adjusting its eccentricity. The structure and working principle of the device are introduced in detail. Carbon fiber (CF)/polyamide 6 (PA6) composites are prepared via this novel mixing device. The influences of eccentricity and mixing time on the morphology, CF length, thermal, mechanical, and electrical properties of CF/PA6 composites are studied. Scanning electron microscopy results show that CFs uniformly disperse in the matrix and interfacial adhesion between CFs and PA6 is improved. It is observed that CF length and its distributions can be optimized by changing eccentricity. The maximum average fiber length is about 351 μm. Differential scanning calorimetry results exhibit that the Xc increases 6.5% when eccentricity is 2 mm. Mechanical test results show tensile strength and modulus increase first and then decrease with the increasing eccentricities or mixing time. Electrical property measurement shows an obvious increase when eccentricity is 2 mm due to good fiber dispersion and long fiber retention length. The experimental results indicate that the novel mixing method and its corresponding apparatus provide an environment‐friendly and effective way to prepare polymer‐based composites.
Noisy Effect on Nonlinear Quantum Search Algorithm
Authors: Tchapet Njafa Jean‐Pierre , Nana Engo Serge Guy 
Published: April 2021

AbstractIn this paper, we investigate the effects of three single‐qubit quantum noise channels on the quantum nonlinear search algorithm proposed by Abrams and Lloyd. We focus on the gates of the nonlinear part of the algorithm and consider the case where the quantum noise channel only affects the qubit on which the gate is proceeding. Assuming that quantum noise effects occur after using the gates of the nonlinear part of the algorithm, we find that the quantum nonlinear search algorithm appears to be very resilient to the quantum noise when the desired state does not exist in the first register and is subject to the phase damping channel or the depolarising channel.
Interference management via cooperative beam biasing and power control for mmWave satellite clusters
Authors: Zhang Shanghong , Cui Gaofeng , Li Pengxu , Wang Weidong 
Published: April 2021

SummaryIn order to tackle the problem of spectrum scarcity, spectrum sharing among satellite communication systems becomes a common phenomenon. Due to the spectrum sharing, mmWave satellite cluster, which is considered as a prominent part of the space information networks, may suffer severe mutual interference among inter‐satellite data links. In this paper, we firstly conduct the interference analysis for satellite clusters. Then, we formulate the interference problem as a constrained optimization problem in the performance metric of the total achievable data rate. To alleviate the interference between satellite clusters, a particle swarm optimization (PSO)‐based cooperative beam biasing and power control scheme (CBP‐PSO) from the perspectives of the joint beam domain and power domain is proposed. And the interference management problem is transformed to find the best combination of the boresight direction and transmission power based on the improved PSO algorithm. Specially, in the interference analysis and proposed scheme, different satellite cluster formations and antenna configurations are taken into account. Finally, simulation results show that the proposed CBP‐PSO scheme based on cooperative beam biasing and power control can effectively improve the achievable data rate of the interfered data links, even for the severe in‐line interference.
Treatment of Chronic Diabetic Foot Ulcers with Adipose-Derived Stromal Vascular Fraction Cell Injections: Safety and Evidence of Efficacy at 1 Year
Authors: Carstens Michael H. , Quintana Francisco J. , Calderwood Santos T. , Sevilla Juan P. , Ríos Arlen B. , Rivera Carlos M. , Calero Dorian W. , Zelaya María L. , Garcia Nelson , Bertram Kenneth A. , Rigdon Joseph , Dos-Anjos Severiano , Correa Diego 
Published: April 2021

AbstractDiabetes affects multiple systems in complex manners. Diabetic foot ulcers (DFUs) are a result of diabetes-induced microarterial vessel disease and peripheral neuropathy. The presence of arteriosclerosis-induced macroarterial disease can further complicate DFU pathophysiology. Recent studies suggest that mesenchymal stromal cell therapies can enhance tissue regeneration. This phase I study was designed to determine the safety and explore the efficacy of local injections of autologous adipose-derived stromal vascular fraction (SVF) cells to treat nonhealing DFUs greater than 3 cm in diameter. Sixty-three patients with type 2 diabetes with chronic DFU—all amputation candidates—were treated with 30 × 106 SVF cells injected in the ulcer bed and periphery and along the pedal arteries. Patients were seen at 6 and 12 months to evaluate ulcer closure. Doppler ultrasounds were performed in a subset of subjects to determine vascular structural parameters. No intervention-related serious adverse events were reported. At 6 months, 51 subjects had 100% DFU closure, and 8 subjects had ≥75% closure. Three subjects had early amputations, and one subject died. At 12 months, 50 subjects had 100% DFU healing and 4 subjects had ≥85% healing. Five subjects died between the 6- and 12-month follow-up visits. No deaths were intervention related. Doppler studies in 11 subjects revealed increases in peak systolic velocity and pulsatility index in 33 of 33 arteries, consistent with enhanced distal arterial runoff. These results indicate that SVF can be safely used to treat chronic DFU, with evidence of efficacy (wound healing) and mechanisms of action that include vascular repair and/or angiogenesis.