bluuebunny/crossref_metadata_2025_split huggingface dataset:
Microhabitat of Leptophryne borbonica (Tschudi, 1838) (Anura: Bufonidae) and it’s calling behaviour in Sumatera
Authors: Nugraha F A D , Kadafi M , Satria R , Maulidi A 
Published: June 2021

Abstract
Microhabitat use of amphibians have been widely neglected among studies on herpetofauna. The microhabitat structure is important when it served as reproduction site. Here we survey the microhabitat characteristics of Leptophryne borbonica and the mating calls. We observed 15 individuals perching on the rock in the middle of the stream and two others have been observed far from stream and other water bodies. The calling males perch on the moist and dry rocks. Interestingly, this species always calls on the rock which is located right in front of the water that fall from two intersecting rocks, creating the small-like waterfall with very noisy backsound. It might suggest the behavior of hiding from predators detection through the sound of environment.
Production of Antifungal Compounds by Andalas Endophytic Bacteria (Morus macroura Miq.) Isolate ATB 10-6 at Fermentation Medium with Optimum Carbon and Organic Nitrogen Source
Authors: Putri D H , Violita V , Irdawati  , Fifendy M , Nurhasnah N 
Published: June 2021

Abstract
Andalas (Morus macroura Miq.) is one of the endemic plants in West Sumatera, which is known to have bioactive compounds that have the potential as antifungal. One of the effective ways to produce bioactive compounds from the plants is by utilizing endophytic bacteria through a fermentation process. One of the factor that influence fermentation is the medium. The purpose of this study was to see the effect of carbon and organic nitrogen sources on the growth of the Andalas endophytic bacteria ATB 10-6 isolate and its ability to produce antifungal compounds. The carbon sources used were glucose, lactose, maltose, sucrose, and starch. The types of organic nitrogen sources used were yeast extract, malt extract, beef extract and peptone water. Bacterial growth was observed by measuring optical density (OD), while antifungal activity was carried out by diffusion method. The result showed that a starch and yeast extract was the best carbon and organic nitrogen for the Andalas endophytic bacteria growth. These two types of nutrients are also the best sources of organic carbon and nitrogen to produce antifungal compounds.
Soil Movement Analysis Using Geospatial Information System Method in Gunuang Padang Area Batang Arau Village
Authors: Gamela Saldy Tri , Salia Zakri Rizto 
Published: June 2021

Abstract
Batang arau village is an area that has an area around Gunung Padang. Padang Mountain is a small hill in the south of the Padang city which is directly adjacent to the Indian Ocean. Based on existing history, this area has experienced landslides which caused property losses and the loss of the lives of residents in that location. As a tourist area and a fairly densely populated residential area, knowing the areas prone to land movement is a must, so that people understand the potential for land movement that exists in the location where they live. Geospatial information system is a method that can be used to map the soil vulnerability conditions in the research area. Based on the soil movement model developed by Puslittanak in 2004, 6 supporting maps are needed to produce a map of soil movement around the research area, namely, regional geological maps, rainfall maps, geomorphological maps, soil type maps, and rock type maps. The six maps are then combined into one to produce a soil vulnerability map in the research location. Based on the results of research, the area of Batang arau subdistrict is included in areas with medium-very high soil movement vulnerability. Areas that are included in residential areas are in the medium vulnerability category, while areas that are included in the tourism object of Siti Nurbaya are in the very high vulnerability category.
Pre-Service Mathematics Teachers’ Perception on Realistic Mathematics Education
Authors: Rifandi Ronal , Mulyati Asrina , Meutia Rani Maulani , Al Aziz Saddam 
Published: June 2021

Abstract
Realistic Mathematics Education (RME) has a long story of application around the world. Experts belief that it is a prominent approach in teaching and learning mathematics. However, there is a need to analyse whether it still suitable to use in the classroom teaching in preparing students to survive in the 21st century era. Therefore, the aim of this study is to describe pre-service mathematics teachers’ perception about RME. This study is a descriptive research using survey method. The data were collected through questionnaire. The collected data was analysed by using percentage technique. The result shows that there is positive perception of pre-service mathematics teachers in this study towards the use of RME in classroom teaching.
Need Analysis for Physics E-Module Based on Creative Problem Solving Integrated 21st Century Skills
Authors: Widya  , Maielfi Dini , Alfiyandri  
Published: June 2021

Abstract
Online learning is an alternative in the 21st century. Teachers are expected to adapt to these changes by developing teaching materials that are interactive, interesting, and accessed at any time. Besides, the development of teaching materials needs to pay attention to the skills needed by students today. This research is the initial part of development research. This study aims to determine the need of teaching materials that are appropriate for the 21st century. Through student analysis, curriculum analysis, and material analysis for physical learning, information is obtained. It is necessary to develop digital teaching materials in integrated e-modules with Creative Problem-Solving models to achieve 21st-century skills.
Validity and practicality of science learning material by integrating new literacy based on thematic learning for grade VIII students
Authors: Asrizal  , Yurnetti  , Murtiani  , Aprilia Usman Esti 
Published: June 2021

Abstract
The industrial revolution 4.0 requires learning that can develop various literacy skills of students so that they can succeed in learning as well as in everyday life. To answer the challenges of the industrial revolution 4.0, the education world seeks to apply 21st-century learning. Through 21st century learning, science learning can be carried out in an integrated manner supported by thematic learning. However, the real conditions illustrate that the application of thematic learning and the integration of literacy skills in science learning is still low. This happens because the integration of literacy in learning is still very limited. One solution that can be done to overcome this problem is to develop new integrated science teaching materials based on thematic learning based on thematic learning for grade VIII students. The type of this research was research and development. The development of integrated science teaching materials for new literacy based on thematic learning consists of seven stages, namely with potential and problems, information gathering, product design, product design, product validation, product testing, product improvement. The instrument for collecting data consisted of two. First, validity sheets are given to experts. Second, practicality sheets are given to teachers and students. Data analysis techniques used descriptive statistical analysis. Based on data analysis, two research results were obtained. The first validation of science teaching materials about integrated with new literacy and component of validity science learning is good and very good with an average value of 75,17 and 80.15. Second, the practicality of integrated science teaching materials for new literacy based on thematic learning according to teachers and students is very good with an average value of 89.85 and 83.53. Based on the results of the study, it can be indicated that integrated literacy teaching materials for new literacy based on valid and practical thematic learning and can be used in science learning.
Development of Invertebrates Diversity Practical Guide Oriented Contextual Approach for Student in Biology Department
Authors: Selaras GH , Farma SA , Fitri R , Satria R , Nugraha FAD , Atifah Y 
Published: June 2021

Abstract
Practicum is an integral part of science learning which aims to provide opportunities for students to test hypotheses or observe real objects related to concepts or theories. In order for the practicum to be carried out well, it must be facilitated with practical guide. In this study, a practical guide for invertebrates diversity oriented contextual approach was developed. The purpose of this study is to produce a practical guide for invertebrates diversity oriented with contextual approach. The results of this study are a valid practical guide. Based on the research and development that has been done, practical guides that have been developed are in accordance with the established quality standards.
Blended learning best practice to answers 21st century demands
Authors: Faraniza Z 
Published: June 2021

Abstract
Identify and explore various 21st century skills that indicate the demands that must be mastered by a person. This still corresponds to the four pillars of life which include learning to do, learning to know, learning to be, and learning to live together. Education is a means to form these various skills, such as metacognition, critical thinking skills, problem solving, communication skills, and collaboration, information literacy, and various other skills. This research is a descriptive study with a Systematic Literature Review (SLR). This research focuses about designing learning activities that empower metacognition, contextual, and develop student-centered learning to achieve meaningful learning concepts that are expected to gain competent quality output. Various ways can be implemented in the learning process, one of which is by cultivating creativity and innovation in learning through blended learning. The results show that blended learning indicates high learning outcomes compared to online learning and face to face because blended learning is a model that combines the advantages of face-to-face learning models with e-learning models by developing various learning media. Blended learning as an alternative solution to overcome the weaknesses of online learning and face-to-face learning to produce a series of learning that is efficient, effective, and fun for students. The interaction and communication of blended learning between and between teacher-students can continue and this is the main attraction of learning in this 21st century era.
Effect of Collaboration the STAD with Audio Visual Media on IPA Knowledge Competencies of VII Class SMP Negeri 32 Padang
Authors: Azizah N , Lufri  
Published: June 2021

Abstract
Based on the problems found in SMP Negeri 32 Padang that the low competence of students’ knowledge because students being less active in the learning process and finding it difficult to learn IPA. So, solution for the problem is group learning models. The group learning models that can be used is the STAD. STAD can also be collaboration with audiovisual media to make students active and enthusiastic so that they can improve their learning outcomes. The research type is a quasi-experimental research with a population of VII class students of SMP Negeri 32 Padang who were registered in 2018/2019. Sample (experimental class and control class) are taken using purposive sampling technique. The research instrument is test (multiple choice) and data will be analyzed with T-test. The result from this research is knowledge comptency of experimental is higher than the control class (80.53 > 73.40) and make H1 accepted because sig.< 0,05. So, the conclusion is collaboration the STAD model’s with audio visual media have significant effect on IPA knowledge competency of VII Class SMP Negeri 32 Padang.
Development of GGAG alpha camera system for targeted alpha radionuclide therapy research
Authors: Yamamoto S. , Watabe T. , Kaneda-Nakashima K. , Shirakami Y. , Ooe K. , Toyoshima A. , Teramoto T. , Shinohara A. , Hatazawa J. 
Published: June 2021

Abstract
Cerium doped Gd3(GaAl)5O12 (GGAG) scintillator has a character in which the decay time for alpha particles differs from that of gamma photons. This is a good point for an imaging detector used for alpha autoradiography of a mouse administered Astatine-211 (At-211) in radionuclide therapy research. Thus, we developed an alpha camera system using a GGAG imaging detector combined with a charge-coupled device (CCD) camera. Our GGAG imaging detector is made of a 0.5 mm-thick GGAG plate optically coupled to a position sensitive photomultiplier tube (PSPMT) and set in a stand with the CCD camera positioned on the upper side of the imaging detector to take optical photos. We first measured the performance of our alpha camera system using an Am-241 alpha source and natural alpha emitting radionuclides with radon daughters. We then conducted imaging of the non-sliced organs of a mouse. After the imaging detector surface was covered with 2.5 µm-thick Mylar film, the organs of the At-211-administered mouse was set on the imaging detector after split or opened and the alpha emitter distributions were measured. We used pulse shape analysis to separate the alpha particles from the beta particles or gamma photons. We successfully measured the alpha particle distributions of the wet non-sliced organs of the At-211-administered mouse. Using the pulse shape spectrum, we could separate the alpha particle images and beta particle or gamma photon images. We conclude that the developed alpha camera system is promising for the imaging of alpha particles and separating of the images using pulse shape discrimination.
A Pythagorean theorem for partitioned matrices
Authors: Bourin Jean-Christophe , Lee Eun-Young 
Published: June 2021

We establish a Pythagorean theorem for the absolute values of the blocks of a partitioned matrix. This leads to a series of remarkable operator inequalities. For instance, if the matrix

A

\mathbb {A}

is partitioned into three blocks

A
,
B
,
C

A,B,C

, then

|

A

|

3

≥
U

|

A

|

3

U
∗

+
V

|

B

|

3

V
∗

+
W

|

C

|

3

W
∗

,

3

|

A

|

≥
U

|

A

|

U
∗

+
V

|

B

|

V
∗

+
W

|

C

|

W
∗

,

\begin{gather*} |\mathbb {A}|^3 \ge U|A|^3U^* + V|B|^3V^*+ W|C|^3W^*,\\ \sqrt {3} |\mathbb {A}| \ge U|A|U^* + V|B|V^*+ W|C|W^*, \end{gather*}

for some isometries

U
,
V
,
W

U,V,W

, and

μ
4
2

(

A

)
≤

μ
3
2

(
A
)
+

μ
2
2

(
B
)
+

μ
1
2

(
C
)

\begin{equation*} \mu _4^2(\mathbb {A}) \le \mu _3^2(A) +\mu _2^2(B) + \mu _1^2(C) \end{equation*}

where

μ
j

\mu _j

stands for the

j
j

-th singular value. Our theorem may be used to extend a result by Bhatia and Kittaneh for the Schatten

p
p

-norms and to give a singular value version of Cauchy’s Interlacing Theorem.
General triviality for counterfactuals
Authors: Santorio Paolo 
Published: June 2021

Abstract
On an influential line of thinking tracing back to Ramsey, conditionals are closely linked to the attitude of supposition. When applied to counterfactuals, this view suggests a subjunctive version of the so-called Ramsey test: the probability of a counterfactual If A, would B ought to be equivalent to the probability of B, under the subjunctive supposition that A. I present a collapse result for any view that endorses the subjunctive version of the Ramsey test. Starting from plausible assumptions, the result shows that one’s rational credence in a would-counterfactual and in the corresponding might-counterfactual have to be identical.
Fast numerical optimization for genome sequencing data in population biobanks
Authors: Li Ruilin , Chang Christopher , Tanigawa Yosuke , Narasimhan Balasubramanian , Hastie Trevor , Tibshirani Robert , Rivas Manuel A 
Published: June 2021

AbstractMotivationLarge-scale and high-dimensional genome sequencing data poses computational challenges. General-purpose optimization tools are usually not optimal in terms of computational and memory performance for genetic data.ResultsWe develop two efficient solvers for optimization problems arising from large-scale regularized regressions on millions of genetic variants sequenced from hundreds of thousands of individuals. These genetic variants are encoded by the values in the set {0,1,2,NA}. We take advantage of this fact and use two bits to represent each entry in a genetic matrix, which reduces memory requirement by a factor of 32 compared to a double precision floating point representation. Using this representation, we implemented an iteratively reweighted least square algorithm to solve Lasso regressions on genetic matrices, which we name snpnet-2.0. When the dataset contains many rare variants, the predictors can be encoded in a sparse matrix. We utilize the sparsity in the predictor matrix to further reduce memory requirement and computational speed. Our sparse genetic matrix implementation uses both the compact two-bit representation and a simplified version of compressed sparse block format so that matrix-vector multiplications can be effectively parallelized on multiple CPU cores. To demonstrate the effectiveness of this representation, we implement an accelerated proximal gradient method to solve group Lasso on these sparse genetic matrices. This solver is named sparse-snpnet, and will also be included as part of snpnet R package. Our implementation is able to solve Lasso and group Lasso, linear, logistic and Cox regression problems on sparse genetic matrices that contain 1 000 000 variants and almost 100 000 individuals within 10 min and using less than 32GB of memory.Availability and implementationhttps://github.com/rivas-lab/snpnet/tree/compact.
‘The World Is Very Competitive and Cruel, You Won’t Get Any Special Treatment’: Social Work and Youth Policy Discourses in the Neoliberal Era
Authors: Vager-Atias Einat , Krumer-Nevo Michal 
Published: June 2021

Abstract
Young people from ethnic minority groups are at the centre of public concern in modern societies. This article presents the findings of a qualitative study that critically examines the discourses of thirty-three social workers who work with young people of Ethiopian ethnic origin in Israel. The findings reveal three key discourses: the social inclusion discourse, the meritocracy discourse and the social conflict discourse. Alongside the dominance of conservative discourses and neoliberal perceptions of youth and sociocultural group relationships, the findings reveal the existence of a competing critical discourse. The discussion offers a critical and contextual analysis of the field of social work with youth as the basis for a renewed discussion of basic assumptions, values, professional role perceptions and work directions. It notes the critical models that recognise and oppose oppression as an alternative to policymaking, training and practice processes regarding young people from social minority groups.
Extracorporeal membrane oxygenation combined with continuous renal replacement therapy for the treatment of severe burns: current status and challenges
Authors: Song Huapei , Yuan Zhiqiang , Peng Yizhi , Luo Gaoxing 
Published: June 2021

AbstractSevere burns often cause various systemic complications and multiple organ dysfunction syndrome, which is the main cause of death. The lungs and kidneys are vulnerable organs in patients with multiple organ dysfunction syndrome after burns. Extracorporeal membrane oxygenation (ECMO) and continuous renal replacement therapy (CRRT) have been gradually applied in clinical practice and are beneficial for severe burn patients with refractory respiratory failure or renal dysfunction. However, the literature on ECMO combined with CRRT for the treatment of severe burns is limited. Here, we focus on the current status of ECMO combined with CRRT for the treatment of severe burns and the associated challenges, including the timing of treatment, nutrition support, heparinization and wound management, catheter-related infection and drug dosing in CRRT. With the advancement of medical technology, ECMO combined with CRRT will be further optimized to improve the outcomes of patients with severe burns.
Analysis of site-specific glycan profiles of serum proteins in patients with multiple sclerosis or neuromyelitis optica spectrum disorder—a pilot study
Authors: Ip Peng Peng , Li Qiongyu , Lin Wei-Han , Chang Chien-Ching , Fann Cathy Shen-Jang , Chen Huan-Yuan , Liu Fu-Tong , Lebrilla Carlito B , Yang Chih-Chao , Liao Fang 
Published: June 2021

Abstract
Glycosylation is important for biological functions of proteins and greatly affected by diseases. Exploring the glycosylation profile of the protein-specific glycosylation and/or the site-specific glycosylation may help understand disease etiology, differentiate diseases and ultimately develop therapeutics. Patients with multiple sclerosis (MS) and patients with neuromyelitis optica spectrum disorder (NMOSD) are sometimes difficult to differentiate due to the similarity in their clinical symptoms. The disease-related glycosylation profiles of MS and NMOSD have not yet been well studied. Here, we analyzed site-specific glycan profiles of serum proteins of these patients by using a recently developed mass spectrometry technique. A total of 286 glycopeptides from 49 serum glycoproteins were quantified and compared between healthy controls (n = 6), remitting MS (n = 45) and remitting NMOSD (n = 23) patients. Significant differences in the levels of site-specific N-glycans on inflammation-associated components [IgM, IgG1, IgG2, complement components 8b (CO8B) and attractin], central nerve system-damage-related serum proteins [apolipoprotein D (APOD), alpha-1-antitrypsin, plasma kallikrein and ADAMTS-like protein 3] were observed among three study groups. We furthered demonstrated that site-specific N-glycans on APOD on site 98, CO8B on sites 243 and 553 are potential markers to differentiate MS from NMOSD with an area under receiver operating curve value &gt; 0.75. All these observations indicate that remitting MS or NMOSD patients possess a unique disease-associated glyco-signature in their serum proteins. We conclude that monitoring one’s serum protein glycan profile using this high-throughput analysis may provide an additional diagnostic criterion for differentiating diseases, monitoring disease status and estimating response-to-treatment effect.