bluuebunny/crossref_metadata_2025_split huggingface dataset:
Improving compliance with physical distancing across religious cultures in Israel
Authors: Gabay Gillie , Gere Attila , Naamati-Schneider Lior , Moskowitz Howard , Tarabieh Mahdi 
Published: November 2021

Abstract
Background
Physical distancing contains the corona virus, but compliance with physical distancing across religious minorities in Israel has been shown to be relatively poorer than in the majority population. This study tests the power of messages as drivers of willingness to comply with physical distancing across religious minorities in Israel during the first wave of the COVID-19 from March till June 2020.

Methods
896 Israeli Muslims, Druze, Bedouins, Jewish Orthodox, Christians, and Jewish Seculars participated in this conjoint-based experimental design. The size of the total sample and of the subgroups is consistent with the suggested size in conjoint analysis studies, particularly when aiming at stability of coefficients rather than stability of means. The dependent variable was ‘willingness to comply’. Independent variables were known contributors to compliance: perceived risk, practices of physical distancing, ways to assure compliance, and the agent communicating the policy.

Results
A regression analysis indicated minor differences in the power of messages across groups despite dramatic cultural differences amongst them. We identified three distinct mindsets that transcend religious cultures from the responses of the study subjects to various messages and named them “pandemic observers,” “obedient followers,” and “sensitive interpreters.” Compliance of "Pandemic Observers" (n = 306) may be improved by messages such as, “Dangerous virus spreading wildly” and “Health experts suggest what to do but the government is reactive rather than proactive” (β = 14, p < .005). Compliance of "Obedient Followers" (n = 242) may be driven by the messages “Socialize and work only from home, using the internet, e.g. zoom/Skype” and “Everyone should stay 2 m. (6 ft.) apart” (β = 16, p < .0050). Compliance of "Sensitive Interpreters" (n = 249) may be improved by messages such as, “Only people who are 60 and over are to be allowed to buy groceries during first 2 h from opening” and by using the media to publicize the official health policy (β = 8; p < .005).

Conclusions
Mindset-assignment reflects how people think rather than their religious affiliation. A personal viewpoint identifier was developed to predict mindset-assignment and enable health authorities to enhance compliance through mindset-tailored messages for members of each mindset segment. We recommend that health authorities and policy makers consider these different personality types, which range across religious minorities and emphasize the messages that each type responds to in developing and implementing a communication plan to improve physical distancing as an important public health measure.
Prediction of the Tensile Strength of Normal and Steel Fiber Reinforced Concrete Exposed to High Temperatures
Authors: Abdi Moghadam Mehrdad , Izadifard Ramezan Ali 
Published: November 2021

AbstractThe tensile strength of concrete has a great impact on the performance of concrete structures, especially for members exposed to high temperatures. The inclusion of steel fibers in concrete is one of the measures to retrieve the loss of tensile strength. The previous equations for the prediction of the tensile strength, are valid for conventional concrete and can predict the tensile strength after high-temperature exposure. Therefore, they are unsatisfactory for forecasting the tensile strength of plain and steel fiber reinforced concrete under high-temperature exposure. To establish a model that can effectively simulate the tensile strength of plain concrete, specimens with compressive strengths of 20–80 MPa are tested. Then by performing tensile strength tests on the specimens containing various content of steel fiber, an equation for prediction of the tensile strength at the ambient temperature is proposed. Meanwhile, the tensile strength tests are conducted at temperatures of 100–800 °C to develop a model for high-temperature exposure. The results indicate that an increase of compressive strength from 20 to 84 improves the tensile strength by 169.4%, and the incorporation of 0.25 and 0.5% of steel fibers can improve the tensile strength of normal concrete by 58.48 and 80.29% on average at the tested temperatures, respectively. Moreover, the proposed model is able to predict the tensile strength of normal and steel fiber reinforced concrete exposed to high temperatures accurately. This equation would help a wider application of the steel fibers in the construction industry with the risk of a fire accident.
Prion type 2 selection in sporadic Creutzfeldt–Jakob disease affecting peripheral ganglia
Authors: Hofmann Anna , Wrede Arne , Jürgens-Wemheuer Wiebke M. , Schulz-Schaeffer Walter J. 
Published: November 2021

AbstractIn sporadic Creutzfeldt–Jakob disease (sCJD), the pathological changes appear to be restricted to the central nervous system. Only involvement of the trigeminal ganglion is widely accepted. The present study systematically examined the involvement of peripheral ganglia in sCJD utilizing the currently most sensitive technique for detecting prions in tissue morphologically. The trigeminal, nodose, stellate, and celiac ganglia, as well as ganglia of the cervical, thoracic and lumbar sympathetic trunk of 40 patients were analyzed with the paraffin-embedded tissue (PET)-blot method. Apart from the trigeminal ganglion, which contained protein aggregates in five of 19 prion type 1 patients, evidence of prion protein aggregation was only found in patients associated with type 2 prions. With the PET-blot, aggregates of prion protein type 2 were found in all trigeminal (17/17), in some nodose (5 of 7) and thoracic (3 of 6) ganglia, as well as in a few celiac (4 of 19) and lumbar (1 of 5) ganglia of sCJD patients. Whereas aggregates of both prion types may spread to dorsal root ganglia, more CNS-distant ganglia seem to be only involved in patients accumulating prion type 2. Whether the prion type association is due to selection by prion type-dependent replication, or due to a prion type-dependent property of axonal spread remains to be resolved in further studies.
The effects of locking inserts and overtorque on the mechanical properties of a large fragment locking compression plate
Authors: Meyers Kathleen N. , Achor Timothy S. , Prasarn Mark L. , Ahn Jaimo , Khalsa Kevin , Wellman David S. , Lorich Dean G. , Helfet David L. 
Published: November 2021

Abstract
Purpose
The study was to determine the effect of locking hole inserts and their insertion torque on the fatigue life of a large fragment Locking Compression Plate (LCP) under bending forces.

Methods
Fatigue strength of the LCP was examined using cyclic three-point bend testing at 80% yield strength of the construct. Locking hole inserts were used in 2, 4, and 6-hole of a 12-hole plate to simulate three different working lengths. Within each working length, plates were tested without locking inserts serving as the control group. In the experimental groups, inserts were tightened to manufacturer recommendations (4 Nm) and using overtorque (8 Nm).

Results
Significantly fewer cycles to failure were observed in control groups versus the locking hole insert groups for all working lengths (2-hole: 4 Nm p = 0.003, 8 Nm p = 0.003; 4-hole: 4 Nm p = 0.02, 8 Nm p < 0.001; 6-hole: 4 Nm p = 0.004, 8 Nm p < 0.001). There was a statistically significant increase in fatigue strength when using overtorque in the 4-hole (p = 0.04) and 6-hole (p = 0.01) defect groups. This was not shown in the 2-hole defect group (p = 0.99).

Conclusions
By placing locking inserts in the empty locking regions of Combi holes along the working length, the number of cycles to failure was increased. Tightening inserts to twice the recommended insertion torque further increased cycles to failure in longer working length models. A longer fatigue life has the potential to decease the incidence of plate failure especially in the setting of delayed union due to poor intrinsic healing capacity, fractures in the geriatric population, osteoporosis and periprosthetic fractures.
Kinetic modelling of the solid–liquid extraction process of polyphenolic compounds from apple pomace: influence of solvent composition and temperature
Authors: Hobbi Parinaz , Okoro Oseweuba Valentine , Delporte Christine , Alimoradi Houman , Podstawczyk Daria , Nie Lei , Bernaerts Katrien V. , Shavandi Amin 
Published: November 2021

AbstractThis study aims to assess kinetic modelling of the solid–liquid extraction process of total polyphenolic compounds (TPC) from apple pomace (AP). In this regard, we investigated the effects of temperature and solvent (i.e. water, ethanol, and acetone) on TPC extraction over various periods. The highest TPC yield of 11.1 ± 0.49 mg gallic acid equivalent (GAE)/g db (dry basis) was achieved with a mixture of 65% acetone–35% water (v/v) at 60 °C. The kinetics of the solvent-based TPC extraction processes were assessed via first-order and second-order kinetic models, with an associated investigation of the kinetic parameters and rate constants, saturation concentrations, and activation energies. The second-order kinetic model was sufficient to describe the extraction mechanism of TPC from AP. This study provides an understanding of the mass transfer mechanism involved in the polyphenolic compound extraction process, thus facilitating future large-scale design, optimization, and process control to valorize pomace waste.Graphical Abstract
Recent trends in therapeutic strategies for repairing endometrial tissue in intrauterine adhesion
Authors: Ma Junyan , Zhan Hong , Li Wen , Zhang Liqi , Yun Feng , Wu Ruijin , Lin Jun , Li Yangyang 
Published: November 2021

Abstract
Intrauterine adhesion (IUA) is a common gynaecological disease that develops from infection or trauma. IUA disease may seriously affect the physical and mental health of women of childbearing age, which may lead to symptoms such as hypomenorrhea or infertility. Presently, hysteroscopic transcervical resection of adhesion (TCRA) is the principal therapy for IUAs, although its function in preventing the recurrence of adhesion and preserving fertility is limited. Pharmaceuticals such as hormones and vasoactive agents and the placement of nondegradable stents are the most common postoperative adjuvant therapy methods. However, the repair of injured endometrium is relatively restricted due to the different anatomical structures of the endometrium. Recently, the treatment outcome of IUAs has improved with the advancement of hysteroscopic techniques. In particular, the application of bioactive scaffolds combined with tissue engineering technology has proven to have high therapeutic potential or endometrial repair in IUA treatment. Herein, this review has summarized past therapeutic strategies, including postoperative adjuvant therapy, cell or therapeutic molecular delivery therapy methods and bioactive scaffold-based tissue engineering methods. Therefore, this review presented the recent therapeutic strategies for repairing endometrium treatment and pointed out the issues of clinical concern to provide alternative methods for the management of IUAs.
Rasmussen syndrome in a tropical environment: a study of six (6) observations
Authors: Guelngar Carlos Othon , Mohamed Lamine Touré , Mamadou Ciré Barry , Mamady Diakité , Mahadi Konaté , Bachir Abdoul Djibo Hamani , Foksouna Sakadi , Fatimata Djibo Hassane , Naby Camara , Dago François Kassa , Fatimatou Korka Bah , Doussou Camara , Victorine Millimono , Salematou Condé , Aminata Sakho , Mohamed Tafsir Diallo , Souleymane Djigué Barry , Mamadou Saliou Diallo , Fodé Mohamed Soumah , Aminou Sanni Yaya , Daouya Douna Granga , Said Abdallah Rafkat , Mamady Konaté , Souleymane Mbara Diallo , Fodé Abass Cissé , Amara Cissé 
Published: November 2021

Abstract
Background
In sub-Saharan Africa, encephalitis of various etiologies is a major public health problem and Rasmussen syndrome is rarely diagnosed due to under-medicalization. The objective of this study is to describe the clinical and neuroradiological forms, especially since this affection is little known in sub-Saharan Africa as evidenced by the scarcity of publications.

Results
A retrospective, descriptive and analytical study of six (6) cases of Rasmussen syndrome, shows that it is an unrecognized disease in Africa. Men were more represented with a frequency of 67% with a young age. The clinical picture dominated by 100% seizures, mental deterioration and hemiparesis. The etiology is still questionable, probably autoimmune in our study.

Conclusion
Rasmussen syndrome accounts for 3% in 219 patients hospitalized for epileptic conditions. This study shows a clinical profile dominated by recurrent epileptic seizures refractory to the drugs Phenobarbital, Valproic Acid and Carbamazepine, the only antiepileptics available in the country. These results are valid for therapeutic and prognostic discussion.
Network analysis of anxiety and depressive symptoms among quarantined individuals: cross-sectional study
Authors: Abdul Karim Mustafa , Ouanes Sami , Reagu Shuja M. , Alabdulla Majid 
Published: November 2021

Background
The mental health burden of COVID-19 has been examined in different settings. Existing research has relied on the latent variable model in assessing COVID-19-related distress. Network theory provides an alternative framework wherein symptoms are conceptualised as causal, interconnected constituents rather than outcomes of mental disorders.

Aims
To assess networks of self-reported anxiety and depressive symptoms among quarantined individuals.

Method
Consenting individuals in different quarantine centres in Qatar completed the Patient Health Questionnaire Anxiety and Depression Scale. We used partial correlation network methods to illustrate interactions of self-reported psychopathology.

Results
Participants with COVID-19 were significantly older and had a significantly higher proportion of males. The most central node was COVID-19, followed by thoughts of self-harm. COVID-19 status was strongly positively connected to thoughts of self-harm, which was positively connected to psychomotor changes, which were connected to decreased concentration. COVID-19 status was also positively connected to feeling anxious, which was strongly connected to inability to concentrate, which was connected to feeling afraid.

Conclusions
COVID-19 was the most influential factor, with the highest number and strength of connections to psychopathology in a network of anxiety and depressive symptoms in a quarantine setting. Beyond the resolution of the infection, therapeutic interventions targeting psychomotor changes might prove beneficial in reducing suicidality among quarantined individuals with COVID-19. Follow-up with mental health services after COVID-19 infection is needed to restore psychological well-being. Further research is needed to understand the short- and long-term psychological effects of COVID-19, and the outcomes of different therapeutic interventions.
Introduction
Authors: Raengo Alessandra 
Published: November 2021

AbstractThis introduction contextualizes the present issue within the question posed by its call for papers: “How does blackness index its own processes?” Following an immanent methodology that seeks formal principles at work within each contribution, it retrieves a variety of archival investments coupled with a shared ethos of critical vulnerability. While approaching blackness as process attempts to think about its ongoingness, it also reaffirms the aesthetic realm as a privileged processing site.
Basic Black
Authors: Sexton Jared 
Published: November 2021

AbstractThis brief essay addresses the quest for “the blackest black,” a totally absorptive, nonreflective surface—in science and engineering as much as in art and entertainment—as an occasion for conceiving difference differently. Here black is both a color and a color space in which other colors become themselves, in their specificity, through a disavowed dependency or derivation, processes whereby we can question the material and symbolic consequences of the meanings ascribed not only to the various colors of the spectrum but also to the very idea of a color spectrum itself.
Alterations in brain glycogen levels influence life-history traits and reduce the lifespan in female Drosophila melanogaster
Authors: Sheshadri Deepashree , Onkar Akanksha , Ganesh Subramaniam 
Published: November 2021

ABSTRACT
Sexual dimorphism in lifespan, wherein females outlive males, is evident across all animal taxa. The longevity difference between sexes is controlled by multiple physiological processes with complex relationships to one another. In recent years, glycogen, the storage form of glucose, has been shown to cause rapid aging upon forced synthesis in healthy neurons. Glycogen in the form of corpora amylacea in the aging brain is also widely reported. While these studies did suggest a novel role for glycogen in aging, most of them have focused on pooled samples, and have not looked at sex-specific effects, if any. Given the widespread occurrence of sex-biased expression of genes and the underlying physiology, it is important to look at the sex-specific effects of metabolic processes. In the present study, using transgenic fly lines for the human glycogen synthase, we investigated the sex-specific effects of glycogen on stress resistance, fitness, and survival. We demonstrate that Drosophila melanogaster females with altered levels of glycogen in the brain display a shortened lifespan, increased resistance to starvation, and higher oxidative stress than male flies. The present study thus provides a novel insight into the sex-specific effect of glycogen in survival and aging and how differences in metabolic processes could contribute to sex-specific traits.
A comparison of two methods for estimating critical swimming speed (Ucrit) in larval fathead minnows: the laminar flow assay and the spinning task assay
Authors: Krzykwa Julie C. , Lamanteer Gabriella S. , Sellin Jeffries Marlo K. 
Published: November 2021

ABSTRACT
Critical swimming speed (Ucrit) is considered a good predictor of swimming capabilities in fish. To estimate Ucrit, a fish is exposed to an incrementally increasing laminar flow of water until it cannot maintain its position against the current. The spinning task assay has been proposed as an alternative method to traditional laminar flow methods; however, these methods have not been directly compared. Thus, the goal of this study was to determine whether the spinning task assay is a suitable alternative to traditional laminar flow assays. To that end, the performance of fathead minnows in each assay was compared at three time points (14, 19 and 24 days post-fertilization, dpf). In 14 dpf fish, Ucrit estimates were similar regardless of the assay used. However, at 19 and 24 dpf, Ucrit estimates derived from the two assay types were significantly different. This indicates that the assays are not equivalent to one another and that the spinning task assay is not a suitable alternative to the laminar flow assay for the determination of Ucrit.
Exercise Reverses Amyloid β-Peptide–Mediated Cognitive Deficits in Alzheimer’s Disease Mice Expressing Mutant Presenilin-2
Authors: Hwang Dong-Joo , Choi Dong-Hun , Kwon Ki-Chun , Kim Eon-Ho , Kim Tae-Kyung , Koo Jung-Hoon , Cho Joon-Yong 
Published: November 2021

ABSTRACT

Purpose
The molecular mechanisms by which physical exercise produces beneficial effects on pathologic features and behavioral symptoms of Alzheimer’s disease (AD) are not well understood. Herein, we examined whether regular moderate exercise could improve cognitive function and produce transcriptomic responses in the brain.

Methods
Four groups of mice were studied: nontransgenic control, mice expressing the human presenilin-2 wild type, mice expressing the human presenilin-2 with the N141I mutation (Tg-PS2m), and Tg-PS2m that were subjected to treadmill exercise (TE) at a speed of 10 m·min−1 for 50 min·d−1, 5 d·wk−1, for 6 wk (Tg-PS2m/Ex).

Results
Tg-PS2m/Ex mice exhibited increased preference in exploring a novel object than Tg-PS2m in the novel object recognition test, whereas differences observed in the water maze test and passive avoidance test were not significant. Western blot and histological analyses using amyloid oligomer (A11) and β-amyloid (6E10) antibody indicated that amyloid oligomer-reactive bands and plaque deposition in the hippocampus were reduced, although not significantly, after TE. Transcriptomic (RNA-sequencing) analysis and subsequent protein analysis revealed that the cell cycle regulatory gene, Cdc28 protein kinase regulatory subunit 2 (Cks2), was decreased, and the cell cycle– and apoptotic cell death–related factors, including cyclin D1, proliferating cell nuclear antigen, and cleaved caspase-3, were increased in the hippocampus of Tg-PS2m, whereas TE reversed their altered expression.

Conclusions
The results support the hypothesis that the pathologic features and behavioral symptoms of AD caused by accumulation of amyloid β-peptide in hippocampus, causing aberrant cell cycle reentry and apoptosis, can be reversed by regular exercise.
Molecular Detection of Sapovirus in Children Under Five Years with Acute Gastroenteritis in Mansoura, Egypt between January 2019 and February 2020
Authors: Zaki Maysaa El Sayed , Shrief Raghdaa , Hassan Rasha H. 
Published: November 2021

Background: Sapovirus has emerged as a viral cause of acute gastroenteritis. However, there is limited data on sapovirus in Egypt. . The present study aimed to evaluate the presence of sapovirus in children with acute gastroenteritis <5 years in Mansoura, Egypt from January 2019 to February 2020 by reverse transcriptase-polymerase chain reaction (RT-PCR). Methods: The cross-sectional study enrolled a 100 children <5 years who presented with acute gastroenteritis at an outpatient clinic in Mansoura, Egypt between January 2019 and February 2020. Clinical data, demographic data and a stool sample was collected from each child. Stools were screened by microscopy for parasites and culture methods for bacteria and excluded from the study if positive for either. Specimens were also screened for rotavirus by enzyme immune assays (EIA) and sapovirus by reverse transcription PCR. Results: The most frequently detected virus was rotavirus by ELISA 25% (25/100). RT-PCR detected sapovirus in 7% (7/100) of the stool samples. The children with sapovirus were all from rural regions and presented mainly during the winter season in Egypt 42.9% (3/7). The main presenting symptoms were fever 71.4% (5/7) and vomiting 57.1% (4/7). None of the children with sapovirus had dehydration. Rotavirus was significantly associated with sapovirus infections in five samples (5/7) , 71.4%, P=0.01. Conclusion: The present study highlights the emergence of sapovirus as a frequent pathogen associated with acute gastroenteritis in children. There is a need for a national survey program for the study of sapovirus among other pathogens associated with acute gastroenteritis for better management of such infection.