bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Study of Land Use Change from Agricultural to Residential Infrastructure Development in Takalar
Authors: Aryadi R , Abdurrahman A , Maricar F 
Published: September 2021

Abstract
Agricultural land has a strategic role and function for Indonesian people who are agrarian. It is due to a large number of Indonesians who are depending on the agricultural sector. Thus, land does not only have economic value, but also social value. In the sustainable agricultural development, land is a limited natural resource because the number does not increase but the needs are always increasing. Currently there is a lot of unclear and irregular land management. Land use change is also arising in South Sulawesi, particularly Takalar district. The increasing need for space in urban areas causes high demand for land. The provision of land in the city center is increasingly limited and of course very expensive, so that urban development tends to "take" areas in the suburbs. One of the potential affected areas is the Takalar regency area as part of the MAMMINASATA area development plan (Makassar, Maros, Sungguminasa, Gowa and Takalar) which is currently being promoted. Recently, the changes in land use and function, which originally being served as a food land and turning out become the land for residential infrastructure, are issues that need serious attention against macro food threats. This research will provide an overview of the conversion mapping results of agricultural land that occurred in the Takalar district from 2012 to 2018.
The basic concepts of the sloping hollow breakwater model
Authors: Huddiankuwera A , Rachman T , Thaha M A , Dewa S 
Published: September 2021

Abstract
The breakwater is a beach construction structure that is used to anticipate and control abrasion. The structure of the wave damper has experienced significant developments. One of the structures of the wave damper is a hollow wave breaker. Hollow breakwater has a varied model, besides minimizing wave of reflection, it is also expected to reduce transmission waves. The reason is because of its ability to absorb wave energy and to reduce the energy of incoming waves. This research is a preliminary simulation as the basis for determining the sloping hollow breakwater model. The study was conducted experimentally in a laboratory with the variables studied include the wave period (T), wave height (H), and wavelength (L). Variable water level (d) is arrange with variations of 21, 24, and 27 cm and the model parameters are cylindrical cavity volume (S), square cavity volume (P), and the slope of the breakwater (a). The results of research based on the theory of wave attenuation and previous studies of the hollow/porous shoreline protection model show that the holes and cavities in the proposed model are expected to work to capture the orbital wave flow and reduce their energy in the cavity through the turbulence process.
Spatial mapping of water mass structure in the estuary of Jeneberang river
Authors: Karamma R , Pallu M S , Thaha M A , Hatta M P , Ihsan M 
Published: September 2021

Abstract
This paper presents a geographical information system approach in the description of water mass structure in the vicinity of Jeneberang river estuary. An ArcGIS application has been employed in developing such a description. Tidal effects are alleged to be the factor influencing flow circulation in the estuary, including flow velocity, water level profile, and saltwater intrusions. The research has been measured the element of water mass, including salinity, temperature, and density. The measurements are then charted in spatial models using ArcGISTM, presenting the distribution pattern of water mass structure as the effect of the tidal process.
Hybrid engineering on permeable groins to reduce the longshore current
Authors: Hafid H , Thaha M A , Maricar F , Bakri B 
Published: September 2021

Abstract
This study aims to determine the effectiveness of hybrid engineering technology to be applied to the groin to reduce longshore currents. The application of hybrid engineering as a breakwater and sediment trap in coastal areas has given good results so that it can be developed in permeable groin structures. The research method used is laboratory experimental with physical modeling to make prototypes and conduct tests on the wave flume to determine changes in current velocity against the existence of a hybrid engineering structure with several model scenarios by changing the characteristics of brushwood groin such as length and distance between groin to surface height. water. The expected result of this study is an engineering model of the permeable groin that can function as an efficient and effective hybrid engineering in reducing longshore currents.
Preliminary design of wave energy utilization model simulation for buoy type seawater pumps
Authors: Imran H A , Thaha M A , Hatta M P , Bakri B 
Published: September 2021

Abstract
This study aims to obtain a preliminary design of simulation of a wave-powered seawater pump model with a buoy & vertical motion piston. The concept works are the mechanism of pumping seawater through the piston push and the apparent motion of the buoy up and down by the waves. The hypothesis, that the flow rate and pumping head as research variables were strongly influenced by wave height and period (H & T). Also, it was estimated that it was influenced by the weight and dimensions of the buoy (W & A) and the diameter of the piston tube. Preliminary experiments are carried out to see the performance of the test model and select the experimental variable magnitudes that are adjusted to the capacity of the available equipment and the scale of the model for similarity needs to the prototype conditions. This study will use a wave flume of 15 m long, 30 cm wide, and 50 cm effective height. The wave characteristics of the model to be used are the wave period in 3 variations (T1: 1.3 seconds, T2: 1.4 seconds, T3: 1.5 seconds), the range of wave heights in 3 variations (4 cm, 5 cm, and 6 cm) and water depth in 3 variations (d1: 25 cm, d2: 27 cm, d3: 29 cm). From the simulation design of this model, it is expected that the equation of the discharge and the height of the pumping head will be formulated in the form of dimensionless parameter relationships.
The Infrastructure Performance of Wajo Regency’s Regional Water Company Based on Costumer’s Perceptions
Authors: Darwis I , Selintung M , Bakri B , Arai Y 
Published: September 2021

Abstract
Regional Water Company (PDAM) is a company that serves the clean water needs for Wajo Regency. Because there are still many customers’ complaints, it is deemed necessary to analyze the performance model of PDAM Wajo Regency infrastructure and analyze how to improve its performance. The data collection method used was a questionnaire by distributing to 155 PDAM Wajo Regency customers and then processed using the SPSS application. Based on the condition of the existing PDAM Wajo Regency infrastructure can be categorized as good. The infrastructure performance model of PDAM Wajo Regency based on customer perception is Y = −0,280 + 0.192X1 + 0.229X2 + 0.202X3 + 0.174X4 + 0.226X5, X1 is realiability variable, X2 is tangible variable, X3 is responsiveness variable, X4 is empathy variable, and X5 is assurance variable. Correlation coefficient (R) is 0.993. The assurance variable has the greatest influence at 28,216% performance for PDAM Wajo Regency infrastructure. The average performance of PDAM Wajo Regency infrastructure based on customer perception is 3.75 categorized as having a good performance. How to improve PDAM Wajo Regency performance is according to customer perceptions by developing a water treatment plan (IPA), replacing damaged distribution installations, replacing customers’ damaged water meters, replacing non-functioning main water meters, and replacing damage distribution pipes. regular metering and water tariff review, according to Permendagri Number 71 Year 2016. Training needs to be held for all employees to improve the quality of human resources of PDAM Wajo Regency.
Mechanical properties and corrosion resistance of high performance fiber-reinforced concrete with steel or amorphous alloy fibers
Authors: Li Y , Deng Y G 
Published: September 2021

Abstract
In the present study, steel fiber and amorphous alloy fiber were applied either single-added or hybrid-added to produce high performance fiber-reinforced concrete (HPC). The results showed that the flowability of fresh concrete was reduced and the compressive, splitting and flexural strength was increased by adding fibers to the mixture. However, the effect of amorphous alloy fiber was more pronounced due to the higher aspect ratio compared to steel fiber. Addition of amorphous alloy fiber improves the interfacial structure and results in a greater maximum pull-out load and bond strength, whereas, a smaller interfacial toughness as compared to crimple steel fibers. After wet/dry cycles, the flexural strength and bond strength was raised about 8% and 10% after 3 days experimental period, but reduced 10% and 15% after 30 days experimental period for steel fiber-reinforced concrete (SFRC), however, has little difference for amorphous alloy fiber concrete (AAFRC). Additionally, the hybrid-fiber-reinforced concrete showed superior performance, especially the flexural property as compared to their single-fiber-reinforced counterparts due to combination effect of the two types of fibers which delay the formation of micro-cracks and macro-cracks, respectively.
Emotion in Fiction: State of the Art
Authors: Friend Stacie 
Published: September 2021

AbstractIn this paper, I review developments in discussions of fiction and emotion over the last decade concerning both the descriptive question of how to classify fiction-directed emotions and the normative question of how to evaluate those emotions. Although many advances have been made on these topics, a mistaken assumption is still common: that we must hold either that fiction-directed emotions are (empirically or normatively) the same as other emotions, or that they are different. I argue that we should reject this dichotomy.
MDF-SA-DDI: predicting drug–drug interaction events based on multi-source drug fusion, multi-source feature fusion and transformer self-attention mechanism
Authors: Lin Shenggeng , Wang Yanjing , Zhang Lingfeng , Chu Yanyi , Liu Yatong , Fang Yitian , Jiang Mingming , Wang Qiankun , Zhao Bowen , Xiong Yi , Wei Dong-Qing 
Published: September 2021

AbstractOne of the main problems with the joint use of multiple drugs is that it may cause adverse drug interactions and side effects that damage the body. Therefore, it is important to predict potential drug interactions. However, most of the available prediction methods can only predict whether two drugs interact or not, whereas few methods can predict interaction events between two drugs. Accurately predicting interaction events of two drugs is more useful for researchers to study the mechanism of the interaction of two drugs. In the present study, we propose a novel method, MDF-SA-DDI, which predicts drug–drug interaction (DDI) events based on multi-source drug fusion, multi-source feature fusion and transformer self-attention mechanism. MDF-SA-DDI is mainly composed of two parts: multi-source drug fusion and multi-source feature fusion. First, we combine two drugs in four different ways and input the combined drug feature representation into four different drug fusion networks (Siamese network, convolutional neural network and two auto-encoders) to obtain the latent feature vectors of the drug pairs, in which the two auto-encoders have the same structure, and their main difference is the number of neurons in the input layer of the two auto-encoders. Then, we use transformer blocks that include self-attention mechanism to perform latent feature fusion. We conducted experiments on three different tasks with two datasets. On the small dataset, the area under the precision–recall-curve (AUPR) and F1 scores of our method on task 1 reached 0.9737 and 0.8878, respectively, which were better than the state-of-the-art method. On the large dataset, the AUPR and F1 scores of our method on task 1 reached 0.9773 and 0.9117, respectively. In task 2 and task 3 of two datasets, our method also achieved the same or better performance as the state-of-the-art method. More importantly, the case studies on five DDI events are conducted and achieved satisfactory performance. The source codes and data are available at https://github.com/ShenggengLin/MDF-SA-DDI.
Aurora A Kinase (AURKA) is required for male germline maintenance and regulates sperm motility in the mouse.
Authors: Lester William C , Johnson Taylor , Hale Ben , Serra Nicholas , Elgart Brian , Wang Rong , Geyer Christopher B , Sperry Ann O 
Published: September 2021

AbstractAurora A kinase (AURKA) is an important regulator of cell division and is required for assembly of the mitotic spindle. We recently reported the unusual finding that this mitotic kinase is also found on the sperm flagellum. To determine its requirement in spermatogenesis, we generated conditional knockout animals with deletion of the Aurka gene in either spermatogonia or spermatocytes to assess its role in mitotic and postmitotic cells, respectively. Deletion of Aurka in spermatogonia resulted in disappearance of all developing germ cells in the testis, as expected, given its vital role in mitotic cell division. Deletion of Aurka in spermatocytes reduced testis size, sperm count, and fertility, indicating disruption of meiosis or an effect on spermiogenesis in developing mice. Interestingly, deletion of Aurka in spermatocytes increased apoptosis in spermatocytes along with an increase in the percentage of sperm with abnormal morphology. Despite the increase in abnormal sperm, sperm from spermatocyte Aurka knockout mice displayed increased progressive motility. In addition, sperm lysate prepared from Aurka knockout animals had decreased protein phosphatase 1 (PP1) activity. Together, our results show that AURKA plays multiple roles in spermatogenesis, from mitotic divisions of spermatogonia to sperm morphology and motility.
Data Science in Undergraduate Life Science Education: A Need for Instructor Skills Training
Authors: Emery Nathan C , Crispo Erika , Supp Sarah R , Farrell Kaitlin J , Kerkhoff Andrew J , Bledsoe Ellen K , O'Donnell Kelly L , McCall Andrew C , Aiello-Lammens Matthew E 
Published: September 2021

AbstractThere is a clear demand for quantitative literacy in the life sciences, necessitating competent instructors in higher education. However, not all instructors are versed in data science skills or research-based teaching practices. We surveyed biological and environmental science instructors (n = 106) about the teaching of data science in higher education, identifying instructor needs and illuminating barriers to instruction. Our results indicate that instructors use, teach, and view data management, analysis, and visualization as important data science skills. Coding, modeling, and reproducibility were less valued by the instructors, although this differed according to institution type and career stage. The greatest barriers were instructor and student background and space in the curriculum. The instructors were most interested in training on how to teach coding and data analysis. Our study provides an important window into how data science is taught in higher education biology programs and how we can best move forward to empower instructors across disciplines.
Random walks on weighted networks: a survey of local and non-local dynamics
Authors: Riascos A P , Mateos José L 
Published: September 2021

AbstractIn this article, we present a survey of different types of random walk models with local and non-local transitions on undirected weighted networks. We present a general approach by defining the dynamics as a discrete-time Markovian process with transition probabilities expressed in terms of a symmetric matrix of weights. In the first part, we describe the matrices of weights that define local random walk dynamics like the normal random walk, biased random walks and preferential navigation, random walks in the context of digital image processing and maximum entropy random walks. In addition, we explore non-local random walks, like Lévy flights on networks, fractional transport through the new formalism of fractional graph Laplacians, and applications in the context of human mobility. Explicit relations for the stationary probability distribution, the mean first passage time and global times to characterize random walks are obtained in terms of the elements of the matrix of weights and its respective eigenvalues and eigenvectors. Finally, we apply the results to the analysis of particular local and non-local random walk dynamics, and we discuss their capacity to explore several types of networks. Our results allow us to study and compare the global dynamics of different types of random walk models.
3D Analysis of maxillary incisor root inclinations in cases of unilateral maxillary canine impaction
Authors: Light Nathan , Chaushu Stella , Major Paul W , Flores-Mir Carlos 
Published: September 2021

Summary

Objectives
To evaluate the association between maxillary incisor root inclinations and unilateral canine impaction.

Methods
A retrospective cross-sectional study of 59 pre-treatment CBCT scans (23 palatal impactions, 10 buccal impactions, and 26 comparison patients). Using Dolphin 3-D Imaging software (Chatsworth, CA), relative incisor angulations to a 3D palatal plane and the shortest distance between the canine crown and the root of the closest lateral incisor were calculated. A one-way analysis of variance was used to determine whether there were any differences between the three independent groups of impactions concerning the four continuous dependent variables incisor root inclination for each maxillary incisor.

Results
Patients with unilaterally impacted maxillary canines demonstrate significant differences in the root inclination position on the ipsilateral (0.0001 &gt; P = 0.002) but not contralateral side. While palatal impactions (PIC) are associated with buccally positioned roots of the ipsilateral lateral (−9.05 degrees) and central incisors (−7.91 degrees), buccal impactions (BIC) are only associated with palatally positioned roots of the ipsilateral lateral incisors (+10.40 degrees) alone. A more labial position of the lateral incisor root was correlated with a more proximally located, coronally positioned, and medially displaced adjacent PIC (0.013 &gt; P &lt; 0.026).

Limitations
This is a retrospective cross-sectional convenience sample.

Conclusions
Patients with impacted maxillary canines, whether PIC or BIC, do not show generalized retroclination or proclination of all four maxillary incisor roots. Instead, changes in incisor root inclination were only ipsilateral to the impacted canine. BIC is only associated with palatal displacement of the ipsilateral lateral incisor root, whereas PIC is associated with labial root displacement of both ipsilateral incisors.
Hypertensive disorders of pregnancy and onset of chronic hypertension in France: the nationwide CONCEPTION study
Authors: Boucheron Pauline , Lailler Grégory , Moutengou Elodie , Regnault Nolwenn , Gabet Amélie , Deneux-Tharaux Catherine , Kretz Sandrine , Grave Clémence , Mounier-Vehier Claire , Tsatsaris Vassilis , Plu-Bureau Geneviève , Blacher Jacques , Olié Valérie 
Published: September 2021

Abstract

Aims
Hypertensive disorders of pregnancy (HDP) are a leading cause of maternal and foetal morbidity and mortality. We aimed to estimate the impact of HDP on the onset of chronic hypertension in primiparous women in the first years following childbirth.

Methods and results
This nationwide cohort study used data from the French National Health Data System (SNDS). All eligible primiparous women without pre-existing chronic hypertension who delivered between 2010 and 2018 were included. Women were followed up from six weeks post-partum until onset of hypertension, a cardiovascular event, death, or the study end date (31 December 2018). The main outcome was a diagnosis of chronic hypertension. We used Cox models to estimate hazard ratios (HRs) of chronic hypertension for all types of HDP. Overall, 2 663 573 women were included with a mean follow-up time of 3.0 years. Among them, 180 063 (6.73%) had an HDP. Specifically 66 260 (2.16%) had pre-eclampsia (PE) and 113 803 (4.27%) had gestational hypertension (GH). Compared with women who had no HDP, the fully adjusted HRs of chronic hypertension were 6.03 [95% confidence interval (CI) 5.89–6.17] for GH, 8.10 (95% CI 7.88–8.33) for PE (all sorts), 12.95 (95% CI 12.29–13.65) for early PE, 9.90 (95% CI 9.53–10.28) for severe PE, and 13.17 (95% CI 12.74–13.60) for PE following GH. Hypertensive disorders of pregnancy exposure duration was an additional risk factor of chronic hypertension for all PE subgroups. Women with HDP consulted a general practitioner or cardiologist more frequently and earlier.

Conclusion
Hypertensive disorders of pregnancy exposure greatly increased the risk of chronic hypertension in the first years following delivery.
Trend of antibiotic consumption and its association with influenza-like illnesses in France between 2004 and 2018
Authors: Yaacoub Sally , Lanoy Emilie , Hider-Mlynarz Karima , Saleh Nadine , Maison Patrick 
Published: September 2021

Abstract

Background
Antibiotic consumption has been reported to be driven by the treatment of respiratory tract infections. Our objectives were to describe the trend of antibiotic consumption in France compared with that of other European countries; to describe the evolution of each antibiotic class in France; and to explore the relationship between antibiotic consumption and incidence of influenza-like illnesses.

Methods
In this observational study, antibiotic consumption was reported as defined daily doses per 1000 inhabitants per day in the community and hospital sectors in descriptive and graphical formats, using data from the European Surveillance of Antimicrobial Consumption Network database. The total consumption and the consumption of different classes of antibiotics in France according to time and influenza-like illnesses were studied using multiple linear regression models.

Results
The total consumption of antibiotics in France was constant over the 15 years. It was driven by the community sector (92.8%) and was higher than the consumption of other European Union countries (P-value &lt; 0.001). The beta-lactam penicillins were the most consumed antibiotic class and the only class that increased with time. The multiple linear regression models showed a positive correlation between antibiotic consumption in the community sector and incidence of influenza-like illnesses [B = 0.170, 95% CI (0.088–0.252)]. Similar significant results were shown between other antibiotic classes used in the management of influenza-like illnesses (other beta-lactams, and macrolides, lincosamides and streptogramins) and influenza-like illnesses.

Conclusion
Our results suggest that antibiotics used in the management of respiratory tract infections might be involved in the irrational use of antibiotics.