bluuebunny/crossref_metadata_2025_split huggingface dataset:
Uranotungstite, the only natural uranyl tungstate: Crystal structure revealed from 3D electron diffraction
Authors: Steciuk Gwladys , Kolitsch Uwe , Goliáš Viktor , Škoda Radek , Plášil Jakub , Schmidt Franz Xaver 
Published: August 2021

Abstract
Uranotungstite is an uranyl-tungstate mineral that was until recently only partially characterized with a formula originally given as (Fe2+,Ba,Pb)(UO2)2(WO4)(OH)4·12H2O and an unknown crystal structure. This mineral has been reinvestigated by electron microprobe analysis coupled with three-dimensional electron diffraction. According to the electron microprobe data, the holotype material from the Menzenschwand uranium deposit (Black Forest, Germany) has the empirical formula (Ba0.35Pb0.27)Σ0.62[(U6+O2)2(W0.986+☐0.75)O4.7(OH)2.5(H2O)1.75](H2O)1.67 (average of 8 points calculated on the basis of 2U apfu; H2O content derived from the structure). According to the precession-assisted 3D ED data, holotype uranotungstite from Menzenschwand is monoclinic, P21/m, with a = 6.318(5) Å, b = 7.388(9) Å, c = 13.71(4) Å, β = 99.04(13)°, and V = 632(2) Å3 (Z = 2). The structure refinement of the 3D ED data using the dynamical approach (Robs = 0.0846 for 3287 independent observed reflections) provided a structure model composed of heteropolyhedral sheets. A β-U3O8-type sheet of idealized composition [(UO2)2W6+Fe0.253+☐0.75O4.75(OH)1.5(H2O)1.75]0.25– is composed of UO7 polyhedra linked by (W,Fe)O5 polyhedra in which the W:Fe ratio is variable as well as the bulk occupancy of this site; the W site may also host a minor proportion of Cu, Mg, or V. In uranotungstite, the interlayer spaces between adjacent U-W-O sheets host water on one side and, on the other side, a partially occupied cation site mostly occupied by Ba and, to a lesser extent, Pb, as well as a partially occupied H2O site. This work is the first structural description of a natural uranyl-tungstate mineral and confirms the great structural and chemical flexibility of β-U3O8 type of sheets.
Development of multivariate integrated drought monitoring index (MIDMI) for Warangal region of Telangana, India
Authors: Tapas Mahesh R. , Kumar Uday , Mogili Sudhakar , Jayakumar K. V. 
Published: August 2021

Abstract
Agricultural drought is one of the most frequent natural disasters in India's southern part. Remote sensing-based drought indices give advantages in terms of continuous monitoring of land surface. The crop production in the Warangal region in India's southern part is adversely affected due to insufficient rainfall and poor irrigation management. This study aims to develop a multivariate remote sensing-based composite drought index (CDI) to monitor the agricultural drought. Landsat-8 satellite data for all the 11 subregions of Warangal urban and 15 subregions of the rural district of Telangana from 2013 to 2020 for the month of May is used to obtain drought indices. The drought indices are used in this study to develop MIDMI and are compared according to the percentage area of the Warangal region under five different drought categories. In this study, the MIDMI is computed by a weighted average of five vegetation drought indices for the Warangal region as per the method developed by Iyengar and Sudarshan for the multivariate data. MIDMI for all the 26 subregions of the Warangal rural and Warangal urban districts is between 0.4 and 0.6, which makes the Warangal region moderately vulnerable to agricultural drought.
Effects of algae and hydrophytes on the inorganic phosphorus pool of shallow hypereutrophic Lake Taihu
Authors: Li Xiaojun , Xu Xiaoguang , Zhao Yanping , Han Ruiming , Wang Guoxiang 
Published: August 2021

Abstract
Sedimentary phosphorus is a crucial potential source of phosphorus in the eutrophic lake ecosystem. Different ecological types are supposed to affect the presence and variation of sediment phosphorus. On the basis of field investigations, the total sediment phosphorus load in Zhushan Bay was 1,457.48 mg/kg, nearly four times that of the hydrophyte-dominated area. Thereinto, 41.1% was in the form of iron and aluminum-bound phosphorus, which explicitly indicated the phosphorus contamination there. Analytical methods such as Pearson correlation, contamination assessment and principal component analysis were conducted to find out that ‘contamination’ was not equivalent to ‘release risk’. The contamination classification of East Lake Taihu was ‘clean’ in general. However, 63.3% of the total phosphorus could be mobilized under certain conditions. Therefore, light phosphorus loading does not equate to less release risk. In the long run, the implicit phosphorus release by the activation of organic phosphorus in hydrophytic areas needs close attention. This study provides a reference to understand the influence of hydrophytes and algae on the phosphorus cycle of sediment.
GABAB Receptors: are they Missing in Action in Focal Epilepsy Research?
Authors: Avoli Massimo , Lévesque Maxime 
Published: August 2021

:
GABA, the key inhibitory neurotransmitter in the adult forebrain, activates pre- and
postsynaptic receptors that have been categorized as GABAA, which directly open ligand-gated (or
receptor-operated) ion-channels, and GABAB, which are metabotropic since they operate through
second messengers. Over the last three decades, several studies have addressed the role of GABAB
receptors in the pathophysiology of generalized and focal epileptic disorders. Here, we will address
their involvement in focal epileptic disorders by mainly reviewing in vitro studies that have shown:
(i) how either enhancing or decreasing GABAB receptor function can favour epileptiform synchronization
and thus ictogenesis, although with different features; (ii) the surprising ability of GABAB receptor
antagonism to disclose ictal-like activity when the excitatory ionotropic transmission is abolished;
and (iii) their contribution to controlling seizure-like discharges during repetitive electrical
stimuli delivered in limbic structures. In spite of this evidence, the role of GABAB receptor function
in focal epileptic disorders has been attracting less interest when compared to the numerous studies
that have addressed GABAA receptor signaling. Therefore, the main aim of our mini-review is to revive
interest in the function of GABAB receptors in focal epilepsy research.
Features of the Course of COVID-19 in Health Care Workers of a Non-infectious
Hospital
Authors: Leonova Marina , Gaisenok Oleg 
Published: August 2021

Background:
Health Care Workers (HCWs) are at high risk of SARS-COV-2 infection
and COVID-19 disease, not only in the chain of care for COVID-19 patients but also in non-infectious
health care organizations that provide routine medical care to the population.

Objective:
To analyze features of the course of COVID-19 in HCWs of a non-infectious hospital
(non-IH).

Methods and Materials:
A retrospective analysis of COVID-19 cases of HCWs of a non-infectious
hospital (non-IH) due to a local outbreak during the “second wave” of the pandemic, despite the
use of PPE.

Results:
7 HCWs out of 23 employees were infected and had a confirmed COVID-19 infection.
All pointed to the presence of contact at work (patients, colleagues) as the main possible contamination
factor. The development of COVID-pneumonia was observed in 4 persons; 2 of them were hospitalized.
The most common symptoms were fever with a maximum temperature rise of 37.8-39
°C, weakness, chest pain, cough, and loss of smell. The duration of the persistence of symptoms of
the disease was up to 16 days. The elimination of coronavirus in most patients was noted after the
10th day.

Conclusion:
HCWs in non-IH providing routine medical care are at increased risk of contracting
COVID-19 due to contact with infected patients or colleagues. The development of COVID-19 disease
in HCWs leads to long-term disability, which creates tension in the work of non-IH. To reduce
the risk of infection for non-IH HCWs, stated precautions are necessary: strict adherence to
PPE use, mandatory testing of SARS-COV-2, and planning observational wards for unexamined
patients hospitalized for medical care for other indications.
MRI Features and Clinical Significance of Spinal Epidural Lipomatosis: All You Should Know
Authors: Spinnato Paolo , Barakat Massimo , Lotrecchiano Ludovica , Giusti Davide , Filonzi Giacomo , Spinelli Daniele , Pipola Valerio , Moio Antonio , Tetta Cecilia , Ponti Federico 
Published: August 2021

:
Spinal epidural lipomatosis (SEL) is defined as the abnormal accumulation of unencapsulated adipose tissue in the spinal epidural space. SEL can be asymptomatic or can cause a wide range of symptoms, the most common of which is neurogenic claudication. Several other neurological manifestations may also occur, above all myelopathy and radicular symptoms. The spinal level most frequently involved in patients with SEL is the lumbar one, followed by the thoracic one.
Imaging plays a key role in disease assessment. MRI is considered the most effective and sensitive modality for diagnosing and staging SEL. Anyway, also CT scan can diagnose SEL. The diagnosis may be incidental (in mild-moderate disease) or may be taken into account in cases with neurological symptoms (in moderate-severe disease).
There are some recognized risk factors for SEL, the most common of which are exogenous steroid use and obesity. Recent studies have found an association between SEL and obesity, hyperlipidemia and liver fat deposition. As a matter of fact, SEL can be considered the spinal hallmark of metabolic syndrome.
Risk factors control represents the initial treatment strategy in patients with SEL (e.g. weight loss, steroid therapy suspension). Surgical decompression may be required when conservative treatment fails or when the patient develops acute/severe neurological symptoms.
NMR-based Metabolomic Techniques Identify the Anticancer Effects of Three Polyphyllins in HepG2 Cells
Authors: Su Feng , Su Weike , Wang Haibo , Wang Yifan , Ye Lv , Zhu Peixi , Gu Jinping 
Published: August 2021

Background:Rhizoma Paridis (RP) is a traditional Chinese herb used for the treatment of tumors, detoxification and hemostasia. Studies show the main components of RP are Polyphyllin I (PPI), polyphyllin VI (PPVI), and polyphyllin VII (PPVII). However, the pharmaco-mechanisms of these compounds are not clear.Objective:By used 1H nuclear magnetic resonance (1H-NMR) based metabolomics approach to identify the Anticancer effects of PPI, PPVI and PPVII in HepG2 cells.Methods:1H nuclear magnetic resonance (1H-NMR) based metabolomics approach was applied to investigate the toxicological effect of PPI, PPVI, PPVII on HepG2 cells. Multivariate statistical analysis was employed to examine the metabolic changes and abnormal metabolic pathways, including Principal Component Analysis (PCA), Partial Least Squares Discriminant Analysis (PLS-DA), and orthogonal PLS-DA (OPLS-DA).Results:The results showed that the effects of metabolic phenotypes were affected separately by PPI, PPVI, and PPVII. The metabolic phenotypes were also changed over time. The characteristic metabolites were varied by affecting different polyphylins, which were identified by the reconstructed OPLSDA loading plots. According to the characteristic metabolites, the mainly disturbed metabolic pathways were found, such as alanine, aspartate and glutamate metabolism, pyruvate metabolism, glycine, serine, and threonine metabolism.Conclusion:The current work could allow us to understand the therapeutic effect of RP in metabolism. It also indicated that RP would be a promising candidate for liver cancer treatment.
Evidence-based Recommendations on Periodontal Practice and the Management of Periodontal Patients During and After the COVID-19 Era: Challenging Infectious Diseases Spread by Airborne Transmission
Authors: Di Spirito Federica , Iacono Vincent J , Alfredo Iandolo , Alessandra Amato , Sbordone Ludovico , Lanza Antonio 
Published: August 2021

Background:
Periodontal care, which was completely suspended during the peak of the SARS-Cov-2 pandemic and was delayed and recurrently discontinued during the succeeding waves, must be safely provided in the COVID-19 era.

Objectives:
The study aimed to provide recommendations on periodontal practice, optimizing safety, ergonomics, and economic resources, and the management of periodontal patients, ensuring continuity, timing, and effectiveness of periodontal care in the COVID-19 era.

Methods:
Reported protocols for the dental practice in the context of the COVID-19 and current evidence on periodontitis treatment and prevention were reviewed.

Results:
Evidence-based recommendations on contamination control and ergonomic improvements for periodontal practice and the management of periodontal patients challenging COVID-19 and airborne infectious diseases have been provided.

Conclusion:
Due to the economic, ergonomic, and ethical concerns raised by limited periodontal care due to the SARS-Cov-2 pandemic, and awareness of other emerging airborne transmitted infections, the periodontal practice should integrate measures minimizing airborne cross-infections and optimizing time-space and economic resources. The management of periodontal patients in the COVID-19 era should comprise less complex treatments and more comprehensive and definitive approaches, reducing emergencies, session length and number, and, concurrently, extending the recall and maintenance intervals. Moreover, it should implement prevention strategies through teledentistry tools and apps, improving periodontal awareness and self-care, and also through the self-reporting of periodontitis and periodontal risk assessment tools, performing both “population-based” and “high-risk” surveillance of periodontitis. Finally, it should enhance inter-professional collaboration, through telehealth networks, especially targeting subjects at high-risk of both periodontitis and systemic disorders, each of the two variously linked to COVID-19 onset and worsening.
Urinary Retention Secondary to Colpocleisis: A Case Report
Authors: Soto-Vega Elena , Cuan-Baltazar Yunam , García-Mora Arturo , Arroyo Carlos 
Published: August 2021

Introduction:
Pelvic Organ Prolapse (POP) is common in older women, and depending on its extent, it is conservative or surgically treated. Colpocleisis is a technique for POP treatment, in which the vaginal canal is closed, entirely or partially, in order to avoid the protrusion of the pelvic structures, with preservation of the urethral meatus in order to preserve normal micturition.

Clinical Case:
We present a case of a 61-year old woman, who 8 years after a colpocleisis, progressed to urinary retention associated with the progressive scarring of the labia, causing the obstruction of the urethral meatus. The patient underwent a labiaplasty with anterior colpoperineoplasty, with complete normalization of her micturition and sexual activity.

Conclusion:
Long term urinary retention complication has not been previously reported in the literature and should be included as a possible adverse event after colpocleisis.
Traumatic Heel Pad Avulsion in a Pediatric Patient
Authors: Kelly Joseph P. , Catoe Benjamin , Khan Mudassar , Antekeier David P. 
Published: August 2021

Introduction:
Heel pad injuries can have devastating and debilitating consequences. All efforts to primarily reapproximate the heel pad should be undertaken. Reconstruction of the heel pad can often require multiple complex surgeries including microvascular flaps and tissue transfers. There is a paucity of successful techniques for primary repair in the literature.

Case Presentation:
In this case report, we describe the successful use of polydioxanone suture with sterile buttons for the repair of the heel pad in a pediatric patient. An 8-year-old male was struck by a vehicle, sustaining a full-thickness heel pad avulsion injury measuring approximately 16-cm in length. The soft tissue was sharply debrided and repaired primarily to the calcaneal periosteum using #1 polydioxanone suture with external suture buttons, and an incisional wound VAC was applied. He was placed into a long-leg bent knee cast and kept non-weight bearing for a total of 6 weeks, at which time the suture and buttons were removed and he was progressed to weight bearing as tolerated in a walking boot. At the 6-month follow-up examination, the heel pad was viable and well-fixed; the patient reported no pain and was not limited in any chosen activities.

Conclusion:
This construct was shown to provide effective fixation while mitigating reported concerns of tissue necrosis caused by suture repair. At 1 year from injury, the patient’s mother noted a slight limp with running but not with walking. He reported no pain at any time, and his Oxford Ankle-Foot Questionnaire for Children score was 58, indicating excellent patient-reported outcome following his procedures.
Neurovascular Compression in Arterial Hypertension: Correlation of Clinical Data to 3D-Visualizations of MRI-Findings
Authors: Manava Panagiota , Hastreiter Peter , Schmieder Roland E. , Jung Susanne , Fahlbusch Rudolf , Dörfler Arnd , Lell Michael M. , Buchfelder Michael , Naraghi Ramin 
Published: August 2021

Aims:
In this study, we attempted to identify clinical parameters predicting the absence or presence of Neurovascular Compression (NVC) at the Ventrolateral Medulla (VLM) in arterial hypertension (HTN) in MRI findings.

Background:
Cardiovascular and pulmonary afferences are transmitted through the left vagus and glossopharyngeal nerve to the brain stem and vasoactive centers. Evidence supports the association between HTN and NVC at the left VLM. Several independent studies indicate a reduction of HTN after Microvascular Decompression (MVD) of the left. Several independent studies indicate a reduction of HTN after Microvascular Decompression (MVD) of the left VLM. Image processing of MRI provides comprehensible detection of NVC. HTN affects hemodynamic parameters and organs.

Objective:
This study analyzes and correlates clinical data and MRI findings in patients with and without NVC at the VLM in treatment resistant HTN to obtain possible selection criteria for neurogenic hypertension.

Methods:
In 44 patients with treatment resistant HTN, we compared MRI findings of neurovascular imaging to demographic, clinical and lifestyle data, office and 24-hour ambulatory Blood Pressure (BP), and cardiovascular imaging and parameters.

Results:
Twenty-nine (66%) patients had evidence of NVC at the VLM in MRI. Sixteen patients (36%) had unilateral NVC on the left side, 7 (16%) unilateral right and 6 (14%) bilateral NVC. Fifteen (34%) had no evidence of NVC at the VLM. Patients with left sided NVC were significantly younger, than those without NVC (p=0.034). They showed a statistically significant variance in daytime (p=0.020) and nighttime diastolic BP (p<0.001) as the mean arterial pressure (p=0.020). Other measured parameters did not show significant differences between the two groups.

Conclusion:
We suggest to examine young adults with treatment resistant HTN for the presence of NVC at VLM, before signs of permanent organ damage appear. Clinical and hemodynamic parameters did not emerge as selection criteria to predict NVC. MVD as a surgical treatment of NVC in HTN is not routine yet as a surgical treatment of NVC in HTN is not routine yet. Detection of NVC by imaging and image processing remains the only criteria to suggest MVD, which should be indicated on an individual decision.
Understanding the Application and Use of Indigenous Research Methodologies in the Social Sciences by Indigenous and Non-Indigenous Scholars
Authors: Pidgeon Michelle , Riley Tasha 
Published: August 2021

Indigenous research methodologies articulate how researchers and Aboriginal communities engage in research together. These methodologies are informed by Indigenous cultural and ethical frameworks specific to the Nations with whom the research is being conducted. This study explores how such research relationships were articulated in the dissemination phase of research. We carried out an Indigenous qualitative content analysis of 79 peer-reviewed articles published January 1996 to June 2018, predominantly in the fields of social sciences. Our findings show that most articles were written by Indigenous researchers or a research team composed of Indigenous and non-Indigenous researchers. Such collaborations articulated the principles of Indigenous methodology (IM) much clearer than those authored by non-Indigenous scholars or when partnerships with Indigenous communities were less evident with respect to the principles guiding the research process. The principles of IM that were manifest in these research partnerships were relevance, respect for Indigenous knowledges, responsible relationships, wholism, and Indigenous ethics. The findings of this study will help to guide future researchers who work with Indigenous peoples, especially with respect to the need for a deeper understanding of how such research relationships are sustained over time to bring about meaningful change for Indigenous peoples and their communities.
Export Support by Regions: Experience of the Republic of Tatarstan
Authors: Gimatdinov R. R. 
Published: August 2021

The article presents an argument for participation of federative units in the formation of the territories’ export potential and determines the main directions of organizing support for exporters on regional level.Article studies the variety of approaches described in the scientific literature to the forming of infrastructure for export development, implementation and ensuring the effectiveness of measures to support exporters, building up export potential, assimilation of modern technologies for sales organization. The export promotion activities of the Republic of Tatarstan are classified according to the main trends identified in the work. There are described practices of the Republic of Tatarstan on the formation and implementation of export potential, which are of interest for study and implementation by other constituent entities of the Russian Federations.Topical areas of further work include the implementation of a program-targeted approach for supporting the export of small and medium-sized businesses, improving the forms of online sailing and promoting goods, enhancing interaction with trade missions of the Russian Federation and foreign missions of the Russian Export Center.
Comparative Analysis of Memory and Alertness in the Perioperative Period of Operative Delivery in Pregnant Women With Preeclampsia and Without it With Different Kinds of Anesthesia
Authors: Shchegolev A. V. , Shirokov D. M. , Chernykh O. A. , Bogomolov B. N. , Levshankov A. I. 
Published: August 2021

Relevance. The article investigates the choice of anesthesia technique during a caesarean section, which would minimally affect such components of cognitive functions as memory and alertness.The aim of the study is to increase the safety of anesthetic care in women of reproductive age by choosing the method of anesthesia.Material and methods. Two groups of maternity patients were examined: with a normal pregnancy and preeclampsia. They were tested according to a specially designed examination, which included: MoCA test, Benton’s test, Wechsler’s test, self-assessment questionnaire, hospital scale of anxiety and depression before and after surgical delivery.Results. According to the test results, it was found that memory and alertness in pregnant women were initially reduced (compared to the norm), especially with concomitant preeclampsia. When comparing the test results before and after abdominal delivery, it was found that the deterioration of memory and alertness parameters occurs less after the use of neuraxial methods (spinal and epidural anesthesia) compared to patients who underwent general combined anesthesia.