bluuebunny/crossref_metadata_2025_split huggingface dataset:
Towards Interlinked FAIR Biodiversity Knowledge: The BiCIKL perspective
Authors: Penev Lyubomir , Koureas Dimitrios , Groom Quentin , Lanfear Jerry , Agosti Donat , Casino Ana , Miller Joe , Arvanitidis Christos , Cochrane Guy , Barov Boris , Hobern Donald , Banki Olaf , Addink Wouter , Kõljalg Urmas , Ruch Patrick , Copas Kyle , Mergen Patricia , Güntsch Anton , Benichou Laurence , Benito Gonzalez Lopez Jose 
Published: September 2021

The Horizon 2020 project Biodiversity Community Integrated Knowledge Library (BiCIKL) (started 1st of May 2021, duration 3 years) will build a new European community of key research infrastructures, researchers, citizen scientists and other stakeholders in biodiversity and life sciences. Together, the BiCIKL 14 partners will solidify open science practices by providing access to data, tools and services at each stage of, and along the entire biodiversity research and data life cycle (specimens, sequences, taxon names, analytics, publications, biodiversity knowledge graph) (Fig. 1, see also the BiCIKL kick-off presentation through Suppl. material 1), in compliance with the FAIR (Findable, Accessible, Interoperable and Reusable) data principles. The existing services provided by the participating infrastructures will expand through development and adoption of shared, common or interoperable domain standards, resulting in liberated and enhanced flows of data and knowledge across these domains.
BiCIKL puts a special focus on the biodiversity literature. Over the span of the project, BiCIKL will develop new methods and workflows for semantic publishing and integrated access to harvesting, liberating, linking, and re-using sub-article-level data extracted from literature (i.e., specimens, material citations, sequences, taxonomic names, taxonomic treatments, figures, tables).
Data linkages may be realised with different technologies (e.g., data warehousing, linking between FAIR Data Objects, Linked Open Data) and can be bi-lateral (between two data infrastructures) or multi-lateral (among multiple data infrastructures). The main challenge of BiCIKL is to design, develop and implement a FAIR Data Place (FDP), a central tool for search, discovery and management of interlinked FAIR data across different domains.
The key final output of BiCIKL will the future Biodiversity Knowledge Hub (BKH), a one-stop portal, providing access to the BiCIKL services, tools and workflows, beyond the lifetime of the project.
L’élimination diagrammatique
Authors: Moktefi Amirouche 
Published: September 2021

L’usage des diagrammes en logique est ancien. Aux débuts de la logique mathématique, ils servent notamment à résoudre le problème de l’élimination. Cela consiste à extraire la conclusion qui découle d’un ensemble de prémisses en éliminant les termes et les propositions indésirables ou superflus. À cette fin, les logiciens inventent une multitude de notations. Il convient dès lors de s’interroger sur la place des méthodes diagrammatiques dans ce programme de recherche ainsi que leurs interactions avec les autres méthodes de résolution, symboliques et mécaniques. Les diagrammes éliminent-ils vraiment ?
Métamorphoses de l’arbre : du schème au diagramme et du corail au rhizome
Authors: Dahan-Gaida Laurence 
Published: September 2021

Paradigme même du diagramme, l’arbre a fait l’objet des convocations les plus variées dans des domaines et aux fins les plus diverses : outil mnémotechnique, modèle d’organisation de la connaissance, hiérarchies conceptuelles, relations généalogiques, processus héréditaires, modélisation de l’histoire ou de l’évolution naturelle, etc. De l’arbre de Porphyre à l’arbre des encyclopédistes, de l’arbre darwinien de la vie aux arbres de l’histoire littéraire de Franco Moretti, les diagrammes arborescents témoignent d’une capacité apparemment infinie à se laisser réactiver pour délivrer des potentiels inédits, quitte parfois à faire émerger des contre-figures comme le rhizome de Deleuze et Guattari, ou encore le corail de Darwin. Cette capacité de métamorphose de l’arbre, qui est explorée ici, explique pourquoi il est souvent considéré comme le diagramme des diagrammes.
Refractive Outcomes Using Intraoperative Aberrometry for Highly Myopic, Highly Hyperopic, and Post-refractive Eyes
Authors: Soifer Matias , Passi Samuel F. , Wisely C. Ellis , Raufi Nikolas N. , Thompson Atalie C. , Kim Terry , Gupta Preeya K. 
Published: September 2021

PURPOSE:
To evaluate whether intraoperative aberrometry improves the accuracy of refractive outcomes after cataract surgery in highly myopic, highly hyperopic, and post-refractive eyes.

METHODS:
This single-center, retrospective review compared the spherical equivalent of postoperative refraction to that predicted by the Barrett Universal II formula versus Optiwave Refractive Analysis (ORA) (Alcon Laboratories, Inc) for highly myopic and hyperopic eyes and to the Barrett True K formula versus ORA for post-refractive eyes. The number and magnitude of lens changes were analyzed and used to determine in how many cases refractive surprises were affected by ORA, with additional subanalysis of outcomes based on average keratometry values.

RESULTS:

ORA led to a change in the lens power implanted in 48% (96 of 198) of eyes, and prevented hyperopic surprise in 27% (15 of 55) and excess myopia in 46% (19 of 41). Steeper keratometry values correlated with more frequent changes on ORA-recommended implanted intraocular lens (
P
= .0031). ORA led to a similar percentage of eyes falling within ±0.50, ±0.75, and ±1.00 diopters compared to the Barrett Universal II and Barrett True K formulas. In post-refractive eyes, ORA led to a similar mean absolute error when compared to the Barrett True K formula (
P
= .62). For highly myopic eyes with an axial length of greater than 27 mm, ORA demonstrated a trend toward lower mean absolute error when compared to the Barrett Universal II formula (
P
= .076).

CONCLUSIONS:
ORA demonstrated similar refractive results to the Barrett True K formula in post-refractive eyes and to the Barrett Universal II formula in highly myopic and hyper-opic eyes and may provide additional benefit for eyes with steeper corneas or an axial length of greater than 27 mm.

[
J Refract Surg
. 2021;37(9):609–615.]
Biomechanical Response After Corneal Cross-linking With Riboflavin Dissolved in Dextran Solution Versus Hydroxypropyl Methylcellulose
Authors: Fischinger Isaak , Seiler Theo G. , Wendelstein Jascha , Tetz Kristin , Fuchs Barbara , Bolz Matthias 
Published: September 2021

PURPOSE:
To evaluate corneal stiffening in porcine eyes induced by corneal cross-linking (CXL) using riboflavin dissolved in either aqueous dextran or hydroxypropyl methylcellulose (HPMC) solution.

METHODS:

Fifty-one porcine corneas were divided into three groups of 17 each. After deepithelialization, the first (Dresden) group was treated for 30 minutes with 0.1% riboflavin (riboflavin-5-monophosphate in 0.9% NaCl) dissolved in hypertonic 20% dextran and the second (HPMC) group for 30 minutes with isotonic solution containing 0.1% riboflavin and 1.1% HPMC. Thereafter, corneas of both groups were irradiated using 5.4 J/cm
2
(irradiance of 9 mW/cm
2
for 10 minutes; 10*9). After CXL, all corneas were kept in an isotonic 16% dextran bath for 2 hours to obtain an equal hydration state. The third group served as the control group. Stress-strain measurements were performed on 5-mm–wide strips. Corneal thickness was monitored throughout the entire course of the experiments.

RESULTS:

The required stress for a 10% strain was increased by 83% in the Dresden group and 35% in the HPMC group compared to the control group. Resultant Young's modulus (at 10% strain) was 2.53 ± 0.73, 1.87 ± 0.50, and 1.47 ± 0.44 Pa for the Dresden, HPMC, and control groups, respectively. The differences between the Dresden and HPMC groups (
P
= .006), the Dresden and control groups (
P
< .001), and the HPMC and control groups (
P
= .014) were statistically significant. Pachymetry measurements showed a significantly increased corneal thickness after application of HPMC compared with the Dresden group (
P
= .002) and control group (
P
= .041).

CONCLUSIONS:
The biomechanical stiffening of the cornea by CXL can be achieved using dextran- and HPMC-based riboflavin solutions in porcine corneas with an application time of 30 minutes. Dextran-based riboflavin solutions seem to induce a slightly stronger biomechanical response in this setting. HPMC solutions induce less thinning than dextran solutions.

[
J Refract Surg
. 2021;37(9):631–635.]
Macrophagic Extracellular Vesicle CXCL2 Recruits and Activates the Neutrophil CXCR2/PKC/NOX4 Axis in Sepsis
Authors: Wang Guozhen , Huang Weichang , Wang Shuanghu , Wang Jun , Cui Wanfu , Zhang Wenyong , Lou Anni , Geng Shiyu , Li Xu 
Published: September 2021

Abstract
Sepsis is a life-threatening organ dysfunction caused by a dysfunctional host response to infection. Neutrophils play a protective role by releasing antibacterial proteins or by phagocytizing bacteria. However, excess neutrophils can induce tissue damage. Recently, a novel intercellular communication pathway involving extracellular vesicles (EVs) has garnered considerable attention. However, whether EVs secreted by macrophages mediate neutrophil recruitment to infected sites has yet to be studied. In this study, we assessed the chemotactic effect of EVs isolated from mouse Raw264.7 macrophages on mouse neutrophils and found that CXCL2 was highly expressed in these EVs. By regulating CXCL2 in Raw264.7 macrophages, we found that CXCL2 on macrophage EVs recruited neutrophils in vitro and in vivo. The CXCL2 EVs activated the CXCR2/PKC/NOX4 pathway and induced tissue damage. This study provides information regarding the mechanisms underlying neutrophil recruitment to tissues and proposes innovative strategies and targets for the treatment of sepsis.
Self-Renewing Islet TCF1+ CD8 T Cells Undergo IL-27–Controlled Differentiation to Become TCF1− Terminal Effectors during the Progression of Type 1 Diabetes
Authors: Ciecko Ashley E , Schauder David M , Foda Bardees , Petrova Galina , Kasmani Moujtaba Y , Burns Robert , Lin Chien-Wei , Drobyski William R , Cui Weiguo , Chen Yi-Guang 
Published: September 2021

Abstract
In type 1 diabetes (T1D) autoreactive CD8 T cells infiltrate pancreatic islets and destroy insulin-producing β cells. Progression to T1D onset is a chronic process, which suggests that the effector activity of β-cell autoreactive CD8 T cells needs to be maintained throughout the course of disease development. The mechanism that sustains diabetogenic CD8 T cell effectors during the course of T1D progression has not been completely defined. Here we used single-cell RNA sequencing to gain further insight into the phenotypic complexity of islet-infiltrating CD8 T cells in NOD mice. We identified two functionally distinct subsets of activated CD8 T cells, CD44highTCF1+CXCR6− and CD44highTCF1−CXCR6+, in islets of prediabetic NOD mice. Compared with CD44highTCF1+CXCR6− CD8 T cells, the CD44highTCF1−CXCR6+ subset expressed higher levels of inhibitory and cytotoxic molecules and was more prone to apoptosis. Adoptive cell transfer experiments revealed that CD44highTCF1+CXCR6− CD8 T cells, through continuous generation of the CD44highTCF1−CXCR6+ subset, were more capable than the latter population to promote insulitis and the development of T1D. We further showed that direct IL-27 signaling in CD8 T cells promoted the generation of terminal effectors from the CD44highTCF1+CXCR6− population. These results indicate that islet CD44highTCF1+CXCR6− CD8 T cells are a progenitor-like subset with self-renewing capacity, and, under an IL-27–controlled mechanism, they differentiate into the CD44highTCF1−CXCR6+ terminal effector population. Our study provides new insight into the sustainability of the CD8 T cell response in the pathogenesis of T1D.
Education Rights for Stateless Bidoon Children in Kuwait: The Voice of Government Officials
Authors: Mansoor Abdullah 
Published: September 2021

According to the United Nations, a stateless person is someone who has no legal identity in any nation whatsoever. In Kuwait, there are almost 110,000 stateless people who are known as Bidoon, which literally means “without”. Since 1991 Bidoon children have been shut out of the public school system as they are considered illegal immigrants. The only point of contact for legal interaction between the government of Kuwait and the Bidoon is the Central Agency for Remedying Illegal Immigrants’ Status. This complex bureaucracy has two conflicting responsibilities: (1) to investigate claims of citizenship by the Bidoon; and (2) to provide limited government services, including financial support to attend private schools. This research seeks to better understand the government’s position regarding Bidoon education, and present the individual voices and beliefs behind the government policies. Seven government officials were interviewed, including the head of the Central Agency. Their responses, arranged here around specific themes of visibility/invisibility, inclusion/exclusion, and denial/access, suggest some possible explanations for the government’s seeming lack of ability to resolve a situation that has continued for decades. By exploring the multitude of opinions that are impacting government policy, the present study aims to enhance understanding of the political and procedural roadblocks that are preventing the Kuwaiti government from resolving problems around educational access, legal status, and the rights of Bidoon children.
A comunicação de marca entre a publicidade de ontem e as novas gerações de consumidores: tensões e transformações
Authors: De Souza Sandra Maria Ribeiro 
Published: September 2021

A publicidade se encontra em processo de transformação impulsionada, por um lado, pelo uso crescente de tecnologias da informação nas relações interpessoais e de consumo, e por outro, pela quebra das fronteiras rígidas entre as disciplinas de comunicação, decorrente do surgimento de formatos híbridos de ações marcárias, tanto em objetivos quanto em linguagem. O case Devassa Bem Loura, escolhido como exemplar das transformações em curso, ilustra a fase atual da publicidade em tensão entre esquemas criativos do passado e tendências inovadoras de difusão e persuasão.

The advertising industry is undergoing a transformation process driven, on the one hand, by the growing use of information technologies in interpersonal and consumer relations, and on the other hand, by the breakdown of rigid boundaries between communication disciplines, resulting from the emergence of hybrid formats of branding actions, both in objectives and language. The Devassa Bem Loura case, chosen as an example of the ongoing transformations, illustrates the current phase of advertising in tension between past creative schemes and innovative trends of diffusion and persuasion.
Moderate intensity aerobic exercise effects on the quality of life and general health
Authors: Sak Dilara , Dayı Taygun , Günay Erkan , Öniz Adile 
Published: September 2021

Objective:Effects of regular physical activity on the human health is an important factor for the life quality parameters. The present study aimed to determine effects of moderate aerobic exercise on the life quality and human health.Materials and Methods:There were three groups (competitive cyclists, recreational cyclists and control) who voluntarily participated in this study. The cyclists of the National Bicycle Federation who could continue trainings during the Corona virus pandemic (n: 50), cyclists of the amateur clubs (n: 50) and 50 sedentary adults (≥19 years) were enrolled (n:150). World Health Organization Quality of Life Questionnaire Abbreviated Version - WHOQOL-BREF-TR was used to determine participants' life qualities.Results:Competitive cyclists trained for 13.33 (±7.24) hours per week and they had 4798 min/week MET values. Subgroup scores of WHQOL-BREF-TR (physical, psychological, social, environmental, national environment, general life quality and health) were found to be higher in competitive cyclists than others (recreational cyclists and sedentary adults). In addition, the values of competitive and amateur cyclists in the physical health level parameters were higher than the control group. Competitive cyclists had higher scores for psychological, social health and general life quality subgroups than others (p<0.05).Conclusion:The present study showed that if physical activity level increases, general health status and life quality increase. As a result of the study, it was found that moderate-intensity aerobic exercise (2600-4800 MET-min/week energy expenditure) between 7-13 hours a week supports the protection of general health and has positive effects on life quality. There is a need for future research to determine different exercise types, intensity, frequency and their effects on the general health status and life quality.
Influence of Strategic Resource Allocation by Laikipia County Government on Service Delivery in Level 3 and 4 Public Health Facilities
Authors: Lesiyampe Evaline Nasieku , Cherono Vivian , Muriiki Rosemary 
Published: September 2021

Purpose: The purpose of the study was to examine the influence strategic resource allocation by Laikipia county government on service delivery in level 3 and 4 public health facilities.
Methodology: The target population comprised of a sample of 74 medical practitioners. The respondents were doctors, nurses, pharmacists, lab technicians, radiologists, teaching staff and administration staff. Descriptive survey design was adopted for the study. Primary data was collected through questionnaires. Simple random sampling technique was used in guiding the selection of the study sample. A pilot study was conducted in 10 percent of the study sample from Naivasha County. Before administering the instruments, they were subjected to validity checks and reliability tests. Data analysis was done using tools in the SPSS version 25. Analysis involved computation of descriptive statistics such as frequencies, percentages, means and inferential statistics such as Pearson Correlation and regression analysis. The data was then presented in tables and narrations.
Results: The study established that the connection between the strategic resource allocation services and service delivery was statistically positive and significant hence the model can be used to predict the results of level 3 and 4 public health facilities in Laikipia county. It had an R value of .851 and an R square value of .723. Explained further it indicated that strategic resource allocation model forecasted 72.3% change on service delivery. Strategic resource allocation had a β=.324, P=449.
Unique contribution to theory, policy and practice: Though there were resources enough to obtain various medical supplies, there was a gap in ensuring that departments got all the requirements they were in need of. The study discovered that mis-balance between departments getting required resources in which they are dispensed to. The study recommended that there should be clear resource tracking within the departments. There should be easy and less bureaucratic replenishing of the resources since these departments have generated them. There should be policies put into place to factor in quick, reliable and quality replenishing within various departments of hospitals.
Bias and error in modelling thermochronometric data: resolving a potential increase in Plio-Pleistocene erosion rate
Authors: Willett Sean D. , Herman Frédéric , Fox Matthew , Stalder Nadja , Ehlers Todd A. , Jiao Ruohong , Yang Rong 
Published: September 2021

Abstract. Thermochronometry provides one of few methods to quantify rock exhumation rate and history, including potential changes in exhumation rate. Thermochronometric ages can resolve rates, accelerations, and complex
histories by exploiting different closure temperatures and path lengths
using data distributed in elevation. We investigate how the resolution of an exhumation history is determined by the distribution of ages and their
closure temperatures through an error analysis of the exhumation history
problem. We define the sources of error, defined in terms of resolution,
model error and methodological bias in the inverse method used by Herman et
al. (2013) which combines data with different closure temperatures and
elevations. The error analysis provides a series of tests addressing the
various types of bias, including addressing criticism that there is a
tendency of thermochronometric data to produce a false inference of faster
erosion rates towards the present day because of a spatial correlation bias. Tests based on synthetic data demonstrate that the inverse method used by Herman et al. (2013) has no methodological or model bias towards increasing erosion rates. We do find significant resolution errors with sparse data, but these errors are not systematic, tending rather to leave inferred erosion rates at or near a Bayesian prior. To explain the difference in conclusions between our analysis and that of other work, we examine other approaches and find that previously published model tests contained an error in the geotherm calculation, resulting in an incorrect age prediction. Our reanalysis and interpretation show that the original results of Herman et al. (2013) are correctly calculated and presented, with no evidence for a systematic bias.