bluuebunny/crossref_metadata_2025_split huggingface dataset:
A SARS-CoV-2 spike ferritin nanoparticle vaccine protects against heterologous challenge with B.1.1.7 and B.1.351 virus variants in Syrian golden hamsters
Authors: Wuertz Kathryn McGuckin , Barkei Erica K. , Chen Wei-Hung , Martinez Elizabeth J. , Lakhal-Naouar Ines , Jagodzinski Linda L. , Paquin-Proulx Dominic , Gromowski Gregory D. , Swafford Isabella , Ganesh Akshaya , Dong Ming , Zeng Xiankun , Thomas Paul V. , Sankhala Rajeshwer S. , Hajduczki Agnes , Peterson Caroline E. , Kuklis Caitlin , Soman Sandrine , Wieczorek Lindsay , Zemil Michelle , Anderson Alexander , Darden Janice , Hernandez Heather , Grove Hannah , Dussupt Vincent , Hack Holly , de la Barrera Rafael , Zarling Stasya , Wood James F. , Froude Jeffrey W. , Gagne Matthew , Henry Amy R. , Mokhtari Elham Bayat , Mudvari Prakriti , Krebs Shelly J. , Pekosz Andrew S. , Currier Jeffrey R. , Kar Swagata , Porto Maciel , Winn Adrienne , Radzyminski Kamil , Lewis Mark G. , Vasan Sandhya , Suthar Mehul , Polonis Victoria R. , Matyas Gary R. , Boritz Eli A. , Douek Daniel C. , Seder Robert A. , Daye Sharon P. , Rao Mangala , Peel Sheila A. , Gordon Joyce M. , Bolton Diane L. , Michael Nelson L. , Modjarrad Kayvon 
Published: June 2021

AbstractThe emergence of SARS-CoV-2 variants of concern (VOC) requires adequate coverage of vaccine protection. We evaluated whether a spike ferritin nanoparticle vaccine (SpFN), adjuvanted with the Army Liposomal Formulation QS21 (ALFQ), conferred protection against the B.1.1.7 and B.1.351 VOCs in Syrian golden hamsters. SpFN-ALFQ was administered as either single or double-vaccination (0 and 4 week) regimens, using a high (10 μg) or low (0.2 μg) immunogen dose. Animals were intranasally challenged at week 11. Binding antibody responses were comparable between high- and low-dose groups. Neutralizing antibody titers were equivalent against WA1, B.1.1.7, and B.1.351 variants following two high dose two vaccinations. SpFN-ALFQ vaccination protected against SARS-CoV-2-induced disease and viral replication following intranasal B.1.1.7 or B.1.351 challenge, as evidenced by reduced weight loss, lung pathology, and lung and nasal turbinate viral burden. These data support the development of SpFN-ALFQ as a broadly protective, next-generation SARS-CoV-2 vaccine.
ultraID: a compact and efficient enzyme for proximity-dependent biotinylation in living cells
Authors: Zhao Xiyan , Bitsch Sebastian , Kubitz Lea , Schmitt Kerstin , Deweid Lukas , Roehrig Amélie , Barazzone Elisa Cappio , Valerius Oliver , Kolmar Harald , Béthune Julien 
Published: June 2021

AbstractProximity-dependent biotinylation (PDB) combined with mass spectrometry analysis has established itself as a key technology to study protein-protein interactions in living cells. A widespread approach, BioID, uses an abortive variant of theE. coliBirA biotin protein ligase, a quite bulky enzyme with slow labeling kinetics. To improve PDB versatility and speed, various enzymes have been developed by different approaches. Here we present a novel small-size engineered enzyme: ultraID. We show its practical use to probe the interactome of Argonaute-2 after a 10 min labeling pulse and expression at physiological levels. Moreover, using ultraID, we provide a membrane-associated interactome of coatomer, the coat protein complex of COPI vesicles. To date, ultraID is the smallest and most efficient biotin ligase available for PDB and offers the possibility of investigating interactomes at a high temporal resolution.
Prediction of biological age by morphological staging of sarcopenia inCaenorhabditis elegans
Authors: Dhondt Ineke , Verschuuren Clara , Zečić Aleksandra , Loier Tim , Braeckman Bart P. , De Vos Winnok H. 
Published: June 2021

AbstractSarcopenia encompasses a progressive decline in allover muscle quantity and quality. Given its close association with aging, it may represent a valuable healthspan marker. Given the strong commonalities with human muscle structure and the facile visualization possibilities,C. elegansrepresents an attractive model for studying the relationship between sarcopenia and healthspan. However, classical assessment relies on visual scoring of muscle architecture, which is subjective and inaccurate. To resolve this, we have developed an automated image analysis pipeline for the detailed quantification and classification of muscle integrity in confocal microscopy images from a cohort of aging myosin::GFP reporter strains. We then extracted a variety of morphological descriptors and found a subset to scale linearly with age. This allowed us to establish a general linear model that predicts biological age from a morphological muscle signature. To validate the model, we evaluated muscle architecture in long-lived worms that are known to experience delayed sarcopenia by targeted RNAi-mediated knockdown of thedaf-2gene. We conclude that quantitative microscopy allows for staging sarcopenia inC. elegansand will be of use for systematic screening for pharmacological or genetic modulators that mitigate age-related muscle frailty and thus improve healthspan inC. elegans.
The “accountant” stereotype in the Florentine medieval popular culture: “galantuomini” or usurers?
Authors: Carungu Jonida , Molinari Matteo 
Published: June 2021

PurposeThis paper explores the stereotype of the accountant in Florentine medieval popular culture based on literary works and from a historical perspective. It aims to highlight how stereotypes change with time and represent the cultural and historical evolution of a society. This research challenges Miley and Read (2012), who stated that the foundation of the stereotype was in Commedia dell'arte, an Italian form of improvisational theatre commenced in the 15th century.Design/methodology/approachThe authors applied a qualitative research method to examine the accountant from a medieval popular culture perspective. The analysis consists of two phases: (1) categorisation of the accountant stereotype based on accounting history literature and (2) thematic analysis of The Divine Comedy (1307–1313) and The Decameron (1348–1351). The authors explored a synchronic perspective of historical investigation through a “cross-author” comparison, identifying Dante Alighieri as the first key author of medieval popular culture. During his imaginary journey through The Divine Comedy, Dante describes the social, political and economic context of the Florentine people of the 14th century. Then, with its various folkloristic elements, The Decameron of Giovanni Boccaccio becomes the “manifesto” of the popular culture in the Florentine medieval times.FindingsThis study shows the change of the accountant stereotype from the medieval age to the Renaissance. The Divine Comedy mainly connotes a negative accountant stereotype. The 14th century's Florentine gentlemen (“i galantuomini”) are apparently positive characters, with an ordered and clean aspect, but they are accused of being usurers. Dante Alighieri pictures the accountant as a “servant of capitalism”, “dishonest person, excessively fixated with money”, “villain and evil” and “excessively rational”. Giovanni Boccaccio mainly portrays a positive accountant stereotype. The accountant is increasingly more reliable, and this “commercial man” takes a more prestigious role in the society. In The Decameron, the accountant is depicted as a “hero”, “gentleman”, “family-oriented person with a high level of work commitment” and “colourful persona, warm, and emotional”. Overall, the authors provided new evidence on the existence of the accountant stereotype in the Florentine medieval popular.Originality/valueThis study engages with accounting history literature accountants' stereotypes in an unexplored context and time period, providing a base for comparative international research on accounting stereotypes and popular culture. Additionally, it addresses the need for further research on the accountant stereotype based on literary works and from a historical perspective. Therefore, this research also expands the New Accounting History (NAH) literature, focussing on the investigation of the accountant stereotype connotations in the 14th century.
Canola and olive oil gelled emulsions as pork fat replacers in beef burgers
Authors: Dias Maiara Fonseca , Guimarães Angélica Sousa , Benevenuto Júnior Augusto Aloísio , Silva Vanessa Riani Olmi , Fontes Paulo Rogério , Ramos Alcinéia de Lemos Souza , Ramos Eduardo Mendes 
Published: June 2021

PurposeTo meet the consumer demand for a healthier diet, this study emphasizes the feasibility of using vegetable oil gelled emulsions in low-fat industrialized burgers with high contents of polyunsaturated fatty acids (PUFAS). Commercial canola and olive oils have been tested as a relatively inexpensive source of PUFAS.Design/methodology/approachBeef burgers were reformulated by replacing (0, 25, 50, 75 and 100%) pork back-fat with two carrageenan gelled emulsions of vegetable oils (canola and olive oil). The technological characteristics, sensorial properties and the fatty acid profile of reformulated burgers were evaluated.FindingsMoisture content and cooking loss increased and fat and protein contents reduced with higher replacements. Oxidative stability was not affected and replacements of up to 75% did not affect the burger's acceptance. A total fat content reduction of 40% was achieved in burgers with 100% back-fat replacement, improving its nutrient value by increasing the ω−6/ω−3 ratio and decreasing the saturated fatty acids content (in 47%) and the atherogenic (from 0.61 to 0.22) and thrombogenic (from 1.29 to 0.65) indexes. Replacing up to 75% with canola oil gelled emulsion is a promising approach in the design of healthier industrial low-fat burgers.Originality/valueDue to the association of some diseases with the consumption of products rich in saturated fat, the industry looks for alternatives not only to reduce the fat content but also to modify the fatty acid profile in meat products. This study further confirms the possibility of using carrageenan gelled fat replacer in industrialized burgers formulated with meat and other ingredients/additives commonly used to provide economic benefit. Also, confirms the feasibility to use commercial vegetable oils with relatively cheap cost than ω−3 rich oils as the oil phase in the gelled emulsion.
Can the media breed CEO overconfidence? A sociocognitive perspective in the Chinese context
Authors: Ji Yang , Zhou Erhua , Guo Wenbo 
Published: June 2021

PurposeAnchored in the role of a social arbiter, the purpose of this study is to examine whether and how media coverage has an impact on CEO overconfidence and further explore how media ownership and Confucianism affect the relationship in the Chinese context.Design/methodology/approachUsing a sample of 1,492 Chinese listed companies from 2010 to 2015, the study adopts random effects models to empirically analyze the effect of media coverage on CEO overconfidence and the roles of media ownership and Confucianism.FindingsThe paper finds that media coverage is significantly and positively associated with CEO overconfidence, and the positive relationship between media coverage and CEO overconfidence becomes stronger for state-controlled media. What is more, the influence of media coverage on CEO overconfidence is attenuated for those firms located in stronger Confucianism atmosphere. A further analysis reveals that different tenors of media coverage yield asymmetric effects.Originality/valueThe paper provides a new and solid support for the argument that media praise stimulates CEO overconfidence and increases the knowledge about under what conditions CEO overconfidence varies, broadly speaking which fosters the development of upper echelons theory (UET). Meanwhile, the results extend the literature on media effect and information processing. The findings are also beneficial to improve corporate decisions and government regulation on Chinese media systems.
The efficiency of the Italian preventive agreement: a legal, economic and organizational perspective
Authors: Paletta Angelo , Alimehmeti Genc 
Published: June 2021

PurposeThis paper aims to analyze the ex ante and ex post economic efficiency of the preventive agreement (concordato preventivo) or composition with creditors as defined by the Italian Bankruptcy Law. This study examines four possible outcomes of the procedure: homologation (confirmation); the degree of dissent/consent of creditors; the revocation, admissibility or inadmissibility; the declaration of the company bankruptcy in preventive agreement.Design/methodology/approachThis paper uses data from 728 Italian companies which filed for preventive agreement in 2016. In reference to each of the four possible outcomes, this study applies nine logit regressions to analyze the effects of a series of efficiency variables ex ante (corporate-based drivers) and ex post (procedure-based drivers).FindingsResults show the relevance of the debt structure, ownership structure and virtuous behavior, corporate governance and management systems, as well as effectivity of the court control on the preventive agreement outcome.Originality/valueThis paper draws on original data of bankruptcy in Italy and gives empirical evidence of the ex ante and ex post factors on the outcomes of the preventive agreement.
Artificial intelligence and human rights: a comprehensive study from Indian legal and policy perspective
Authors: Chatterjee Sheshadri , N.S. Sreenivasulu 
Published: June 2021

PurposeThe purpose of this study is to investigate the impact of artificial intelligence (AI) on the human rights issue. This study has also examined issues with AI for business and its civil and criminal liability. This study has provided inputs to the policymakers and government authorities to overcome different challenges.Design/methodology/approachThis study has analysed different international and Indian laws on human rights issues and the impacts of these laws to protect the human rights of the individual, which could be under threat due to the advancement of AI technology. This study has used descriptive doctrinal legal research methods to examine and understand the insights of existing laws and regulations in India to protect human rights and how these laws could be further developed to protect human rights under the Indian jurisprudence, which is under threat due to rapid advancement of AI-related technology.FindingsThe study provides a comprehensive insight on the influence of AI on human rights issues and the existing laws in India. The study also shows different policy initiatives by the Government of India to regulate AI.Research limitations/implicationsThe study highlights some of the key policy recommendations helpful to regulate AI. Moreover, this study provides inputs to the regulatory authorities and legal fraternity to draft a much-needed comprehensive policy to regulate AI in the context of the protection of human rights of the citizens.Originality/valueAI is constantly posing entangled challenges to human rights. There is no comprehensive study, which investigated the emergence of AI and its influence on human rights issues, especially from the Indian legal perspective. So there is a research gap. This study provides a unique insight of the emergence of AI applications and its influence on human rights issues and provides inputs to the policymaker to help them to draft an effective regulation on AI to protect the human rights of Indian citizens. Thus, this study is considered a unique study that adds value towards the overall literature.
Opportunities and risks of artificial intelligence in recruitment and selection
Authors: Ore Olajide , Sposato Martin 
Published: June 2021

Purpose
The purpose of this study is to contribute to the knowledge on the opportunities and risks in the use of artificial intelligence (AI) in recruitment and selection by exploring the perspectives of recruitment professionals in a multicultural multinational organisation.

Design/methodology/approach
A qualitative approach was used in this exploratory study. Face-to-face, semi-structured in-depth interviews were conducted with ten professional recruiters who worked for a multinational corporation.

Findings
The findings revealed that AI facilitates the effective performance of routine tasks through automation. However, the adoption of AI technology in recruitment and selection is also fraught with risks that engender fear and distrust among recruiters. The effective adoption of AI can improve recruitment strategies. However, cynicism exists because of the fears of job losses to automation, even though the participants thought that their jobs would continue to exist because recruiters should always be humans.

Originality/value
This paper provides a unique exploration of the opportunities and risks in the adoption of AI for the recruitment and selection function in human resource management. The benefits are the delegation of routine tasks to AI and the confirmation of the crucial role of professional recruiters.
Research on innovative reinforcement of prestressed T-beam bridge
Authors: Zhang Kexin , Tianyu Qi , Dachao Li , Xingwei Xue , Wu Fayue , Liu Xinfeng 
Published: June 2021

PurposeIn order to understand the status of the bridge reinforcement process, the construction process monitoring of the reinforced bridge is carried out. The T-beam bridge was tested using the truck loading test. The displacements and concrete strains of the bridge at mid-span were measured during the test.Design/methodology/approachThis paper describes an innovative technique, external prestressing, used to strengthen a 36-year-old prestressed T-beam bridge. This paper introduces the construction process of the prestressed reinforcement method, and makes a theoretical analysis of the reinforced bridge through the establishment of the reinforcement model.FindingsThis study showed that the structural capacity and performance of the bridge were enhanced with externally prestressed steel strand strengthening.Originality/valueThe innovative reinforcement method of prestressed T-shaped bridge is put forward, which has guiding significance for similar bridge reinforcement and maintenance.
Influence mechanism of surface texture on the output performance of an ultrasonic motor
Authors: Liu Xiaoliang , Huang Xiaoming , Zhang Jian , Sun Weitao 
Published: June 2021

Purpose
The purpose of this study is to investigate the influence mechanism of different interface component surface textures on the ultrasonic motor (USM) output performance.

Design/methodology/approach
The energy transmission mechanism of the traveling-wave ultrasonic motor 60 (TRUM-60) was numerically and experimentally investigated by fabricating dimple textures with different feature types on the friction material and the stator.

Findings
Textured friction material can increase the contact range effectively, and thus, can improve the friction characteristics of the interface and the output performance of the TRUM-60. The experimental results verified the expected influence mechanism and demonstrated that the use of either a textured friction material or stator has a very different effect on USM output performance. A textured PI-based friction material improved the TRUM-60 output performance, resulting in a maximum energy conversion efficiency of 57.11%. However, a textured stator degraded the TRUM-60 output performance, resulting in a minimum energy conversion efficiency of only 44.92%.

Originality/value
The results of this study provide a theoretical foundation for improved USM designs with textured interfaces.
Management accounting developments in German-speaking countries: an overview and editorial reflections
Authors: Becker Albrecht , Pedell Burkhard , Pfaff Dieter 
Published: June 2021

PurposeThis study aims to present a brief overview of developments in management accounting research and practice in German-speaking countries, locate the contributions of this special issue in historical trajectories and provide an outlook of expected future developments in this area.Design/methodology/approachThis study reviews the literature and draws a critically reflective approach.FindingsA century after Schmalenbach, Germanic management and cost accounting have significantly changed, even though the roots of the cost accounting tradition of the late 19th and early 20th centuries are still visible in practice and teaching, which is true for both organisational practice and research. In both cases, an encroachment of the global on the local can be seen but, paradoxically, as Hopwood (1999) noted, the seemingly globally standardised accounting systems allow for local idiosyncrasies to specifically stand out. The anchoring of management accounting in financial accounting, the country-specific ownership and financing models, the importance of capital and labour markets (e.g. strong codetermination) for companies, regulations on corporate governance and the determination of the tax base are examples of institutions that can shape the behaviour of management and, thus, also idiosyncrasies of management accounting in a country.Originality/valueThe contributions of this special issue provide insight into developments in management accounting research and practice in German-speaking countries and, thus, enhance our understanding of the different historical trajectories and traditions in management accounting. The papers by Weber and Wiegmann and by Gischet al.demonstrate how specific idiosyncratic practices and understandings of management accounting in German-speaking countries mediate global influences on management accounting in private- and public-sector organisations. The papers by Endenichet al.and by Kreilkampet al.show that the influence of international developments in management accounting research has become stronger in German-speaking management accounting academia.
Sustainable developments and corporate social responsibility in Vietnamese fashion enterprises
Authors: Nayak Rajkishore , Thang Long Nguyen Van , Nguyen Tu , Gaimster Julia , Morris Rebecca , George Majo 
Published: June 2021

PurposeThe purpose of this research is to investigate the status of sustainable development and corporate social responsibility in fashion enterprises in Vietnam.Design/methodology/approachThis paper is qualitative in nature and utilized a multiple case study approach (questionnaires and face-to-face interviews) to achieve the objectives of the research. NVivo was used to analyze the data.FindingsFindings showed that by collaborating with the local artisans to create the unique clothing lines, the fashion brands try to blend and upscale the traditional indigenous clothing styles with modern design concepts to promote the diversity of Vietnamese ethnic culture. The findings also suggest that both the small and medium-sized enterprises (SMEs) and large enterprises (LEs) should maintain their corporate social responsibility (CSR) concepts to comply with the legal obligations such as salary and welfare benefits for employees, work safety, gender equality and promotions. Further, the CSR activities should address the social issues with their target stakeholders, particularly with the local communities.Originality/valueThis study sought to provide a snapshot on the current sustainable practices followed in Vietnamese fashion enterprises.