bluuebunny/crossref_metadata_2025_split huggingface dataset:
ASPEK BIOLOGI IKAN BELANAK (Mugil cephalus) DI PERAIRAN TELUK BANTEN
Authors: Mourniaty Acacia Zeny Araminta , Nuringtyas Alifa Egitia , Larasati Alya Putri , Septian Futra , Mulyana Ilham , Israwati Waode , Nainggolan Winda , Suharti Ratna , Jabbar Meuthia Aula 
Published: October 2021

Ikan Belanak (Mugil cephalus) Ikan belanak (Mugil cephalus) merupakan salah satu jenis ikan perairan laut yang menggunakan habitat perairan muara sebagai tempat hidupnya termasuk di muara sungai di Teluk Banten. Penelitian ini bertujuan untuk mengetahui aspek biologi ikan belanak meliputi: distribusi ukuran, hubungan panjang bobot, ukuran pertama kali tertangkap (Lc). Pengamatan ini dilakukan pada bulan Maret – April 2019 di perairan Teluk Banten. Hasil penelitian menunjukkan bahwa kisaran ukuran ikan belanak antara 7 – 47 cm. Pola pertumbuhan ikan belanak di Karangantu adalah allometrik negatif (b<3) dengan Lc = 16,70. dan di Domas adalah allometrik negatif (b<3) dan diasumsikan ikan belanak yang tertangkap Di Karangantu nilai Lc>Lm yang mengindikasikan bahwa ikan belanak di lokasi tersebut sudah pernah mengalami pemijahan sebelum tertangkap, sedangkan di Desa Domas nilai Lc<Lm yang mengindikasikan bahwa ikan belanak di lokasi tersebut belum pernah mengalami pemijahan sebelum tertangkap.
Economic Analysis of Integrated Farming Systems in Uttar Kannada District of Karnataka
Authors: Shruthi S.M. , Desai N.R. Mamle 
Published: October 2021

Background: The present study was conducted in Uttar Kannada district of Karnataka as a project on integrated farming systems was implemented in this district by University of Agricultural Sciences, Dharwad during the year 2013-15. It was considered for study in master’s research. Methods: Under the study three taluks viz., Sirsi, Mundagod and Bhatkala were selected with an overall objective of identifying and analyzing and the economics of integrated farming systems. The relevant data collected from primary sources through personal interview method were analyzed by tabular and production function techniques. Four main integrated farming systems followed by majority of the farmers in the study area are selected for study, viz., Integrated Farming System-I,II,III,IV.
Result: The study revealed that the total cost under Integrated Farming Systems-III was highest with Rs. 129023, while it was Rs. 115388, Rs.115266 and Rs. 97434 respectively in Integrated Farming Systems-I,II and IV. net farm returns was highest under Integrated Farming Systems-I which was Rs. 86351. In all the different integrated farming systems, the labour and seed cost had significant influence on gross returns. The seed and feed were underutilized, fertilizer, FYM and land were over utilized.
Variations des caractéristiques physiques et mécaniques du bois de Balanites aegyptiaca en fonction de trois provenances
Authors: DOUGABKA Dao , GÉRARD Jean , BIANZEUBE Tikri , DENDONCKER Morgane , VINCKE Caroline , MARCHAL Rémy , GUIBAL Daniel , GUYOT Alban 
Published: October 2021

Balanites aegyptiaca est une espèce caractéristique et emblématique des zones sèches d’Afrique et d’Asie. Elle revêt une grande importance socio-économique dans toute sa zone naturelle de répartition du fait de ses multiples usages. Toutefois, les propriétés technologiques de son bois sont mal connues, d’où des utilisations parfois inappropriées mais qui pourraient être élargies. Afin de mieux adapter ses applications à ses caractéristiques, nous avons déterminé les indicateurs de stabilité physique (masse volumique, infradensité, retrait radial total, retrait tangentiel total, retrait volumique total et point de saturation des fibres) et les indicateurs de comportement mécanique (module d’élasticité longitudinal, contrainte de rupture en flexion et compression) de ce bois. Quatre-vingt-treize éprouvettes prélevées dans 13 arbres provenant des zones sahélienne et soudanienne tchadiennes, et de la zone sahélienne sénégalaise ont été testées. Les résultats obtenus montrent que, pour les trois provenances, le bois de B. aegyptiaca est mi-lourd (797 kg/m3) avec une stabilité dimensionnelle moyenne : l’anisotropie de retrait est supérieure à 2 (2,2), le retrait radial total et le retrait tangentiel total sont moyens, respectivement égaux à 4 % et 8,5 %. Ses caractéristiques mécaniques sont moyennes (contraintes de rupture en compression et flexion statique respectivement égales à 49,4 MPa et 104,5 MPa) à faible (module d’élasticité longitudinal de 10 473 MPa). Une comparaison des résultats obtenus en fonction des zones de prélèvement a mis en évidence des tendances variables selon les caractéristiques étudiées. Ces variations entre les trois provenances restent cependant limitées. Les résultats de l’étude montrent que le bois de B. aegyptiaca pourrait être utilisé de façon appropriée sous forme de matériau pour une plus large gamme d’emplois, sous réserve de la mise en place d’une gestion adaptée permettant sa restauration par plantation.
Validation of fatty liver index as a marker for metabolic dysfunction-associated fatty liver disease
Authors: Han A lum 
Published: October 2021

Abstract
Aims
Metabolic dysfunction-associated fatty liver disease (MAFLD) is a new nomenclature for nonalcoholic fatty liver. Along with obesity, fatty liver associated with metabolic dysfunction is increasing and has become a serious socioeconomic problem. Non-invasive testing for the confirmation of MAFLD, including the fatty liver index (FLI), can be used as an alternative method for diagnosing steatosis when imaging modalities are not available. To date, few studies have examined the effectiveness and validity of FLI for diagnosing MAFLD. Therefore, this study analyzed the effectiveness and validity of FLI for diagnosing MAFLD.
Methods
Medical records of men and women aged ≥ 19 years who underwent abdominal computed tomography (CT) examination at our facility between March 2012 and October 2019 were retrospectively reviewed. A comparative analysis between non-continuous variables was performed using the chi-squared test. The area under receiver operating characteristic (AUROC) curve was used to verify the effectiveness of FLI as a predictive index for MAFLD.
Results
Analysis of the association between MAFLD and abdominal CT revealed that the sensitivity and specificity of FLI for diagnosing MAFLD were 0.712 and 0.713, respectively. The AUROC of FLI for predicting MAFLD was 0.776.
Conclusions
Our study verified the accuracy of FLI for predicting MAFLD using CT. The FLI can be used as a simple and cost-effective tool for screening MAFLD in clinical settings.
Interleukin-1 receptor antagonist inhibits matastatic potential by down-regulating CXCL12/CXCR4 signaling axis in colorectal cancer
Authors: Ma Jiachi , Liang Wanqing , Qiang Yaosheng , Li Lei , Du Jun , Pan Chengwu , Chen Bangling , Zhang Chensong , Chen Yuzhong , Wang Qingkang 
Published: October 2021

Abstract
Background

The aim of this study was to investigate the co-operative role of CXCR4/ CXCL12 axis and IL-1Ra in metastatic processes mechanism by interactions between colorectal cancer cells and stromal cells in their microenvironment.

Methods

Expression of IL-1α, CXCL12 and CXCR4 mRNA and proteins were determined by RT-PCR and Western blot. The effect of secreted level of CXCL12 by IL-1Ra on fibroblasts was measured by ELISA. CXCL12 regulate metastatic potential of colorectal cancer was evaluated by proliferation, invasion and angiogenesis assays, respectively, in which invasion and angiogenesis assays used an in vitro system consisting of co-cultured colorectal cells and stromal cells.

Results

IL-1α was expressed in high liver metastatic colorectal cancer cell lines (HT-29 and WiDr). The colorectal cancer cell-derived IL-1α and rIL-1α significantly promoted CXCL12 expression by fibroblasts, and this enhancing effect can be significantly inhibited by IL-1Ra ( P<0.01 ). CXCL12 not only enhanced the migration and proliferation of human umbilical vein endothelial cells (HUVECs), but also significantly enhanced angiogenesis ( P<0.01 ). Furthermore, the high liver-metastatic colorectal cancer cell line (HT-29), which secretes IL-1α, significantly enhanced angiogenesis compared to the low liver-metastatic cell line (CaCo-2), which does not produce IL-1α ( P<0.01 ). On the contrary, IL-1Ra can significantly inhibit migration, proliferation and angiogenesis ( P<0.01 ).

Conclusion

Autocrine IL-1α and paracrine CXCL12 co-enhances the metastatic potential of colorectal cancer cells; IL-1Ra can inhibit the metastatic potential of colorectal cancer cells via decrease IL-1α/CXCR4/CXCL12 signaling pathways.
Factors associated with poor Self-rated health in primary care in Malawi
Authors: Kasenda Stephen , Meland Eivind , Hetlevik Øystein , Mildestvedt Thomas , Dullie Luckson 
Published: October 2021

Abstract
Background

Self-rated health (SRH) is a single-item measure of current health, which is often used in community surveys and has been associated with various objective health outcomes. The prevalence and factors associated with SRH in Sub-Saharan Africa remain largely unknown. This study sought to investigate: (1) the prevalence of poor SRH, (2) possible associations between SRH, and socio-demographic and clinical parameters, and (3) associations between SRH and the patients’ assessment of the quality of primary care.
Methods

A cross-sectional study was conducted in 12 primary care facilities in Blantyre, Neno, and Thyolo districts of Malawi among 962 participants who sought care in these facilities. An interviewer-administered questionnaire containing the Malawian primary care assessment tool, and questions on socio-demographic characteristics and self-rated health was used for data collection. Descriptive statistics were used to determine the distribution of variables of interest and binary logistic regression was used to determine factors associated with poor SRH.
Results

Poor SRH was associated with female sex, increasing age, decreasing education, frequent health care attendance, and with reported disability. Patients content with the service provided and who reported higher scores of relational continuity from their health care providers reported better SRH as compared with others.
Conclusion

This study reports findings from a context where SRH is scarcely examined. The prevalence of poor SRH in Malawi is in line with findings from clinical populations in other countries. The associations between poor SRH and socio-demographic factors are also known from other populations. SRH might be improved by emphasizing continuity of care in primary care services.
Cross-cultural Adaptation and Validation of the Korean Version of the Moral Identity Scale in Intensive Care Unit Nurses
Authors: Lee Junghoon , Song Yeoungsuk 
Published: October 2021

Abstract
Background: Korean intensive care unit (ICU) nurses face a variety of moral conflict situations. What makes nurse give up other values and choose moral values? To answer this question, scholars began to study a concept termed “moral identity.” However, despite the increased importance of nurses’ moral identity, it has not been thoroughly studied using empirical data analysis. Instruments developed to predict moral behavior need evidence of their reliability and validity for rigorous research. The purpose of this paper is to report psychometric properties of the Korean version of the Moral Identity Scale in Intensive Care Unit nurses. Methods: The aim of this study was to assess the reliability and validity of the Korean version of the MIS (K-MIS) developed by Aquino & Reed. Data were collected from 207 ICUs. Exploratory and confirmatory factor analysis were used to test the construct validity. Research question/aim/objectives: The aim of this study was to assess the reliability and validity of the Korean version of the MIS (K-MIS) developed by Aquino & Reed.Results: The results of exploratory factor analysis showed that the Eigen values ranged from 1.63 to 4.47 and comprised 52.17% of the total explained variance. Confirmatory factor analysis showed acceptable model fit indices (χ2 (p) = 28.822 (.051), df = 18, root mean square error of approximation = .076, GFI = .937, Tucker-Lewis index = .93, comparative fit index = .955) and standardized factor loadings (.45 to.82). Conclusion: As a professional, the ICU nurse must protect and advocate for the patient. In this respect, K-MIS is a acceptable tool to measure the moral identity of ICU nurses in Korea. Therefore, it is expected that the K-MIS will be used in nursing education programs to improve the moral identity of ICU nurses.
A Novel Hybrid Deep Multi-Criteria Model for Recommender System
Authors: Nassar Nour Salim 
Published: October 2021

Abstract
Recommender systems are everywhere books, products, movies, and more. Traditional recommender systems typically use a single criterion in the recommendation, while studies have shown that multi-criteria recommending is more accurate. Novel deep learning techniques have produced remarkable achievements in many fields. The use of such techniques in recommendation systems has started to get attention recently, and several models of recommendation have been proposed based on deep learning. However, there is still no work for using deep learning in hybrid multi-criteria recommender systems. In this work, a model for a hybrid deep multi-criteria recommender system was presented. The model mainly includes two major parts: In the first one, the model obtains the user ID, item ID, and the item metadata to be used as input to a deep neural network in order to predict the criteria ratings. In the second part, the obtained ratings act as an input to another deep neural network, where the overall rating is predicted. Our experiments were conducted on a real-world dataset. They demonstrated the superiority of the proposed novel model over the other models in all measures used to evaluate performance. This indicates the successful use of hybrid deep multi-criteria in the recommendation systems.
Identification and Fine Mapping of qPBR10-1, A Novel Locus Controlling Panicle Blast Resistance in Pigm-Containing P/TGMS Line
Authors: Wu Yunyu , Xiao Ning , Li Yuhong , Gao Qiang , Ning Yuese , Yu Ling , Cai Yue , Pan Cunhong , Zhang Xiaoxiang , Huang Niansheng , Zhou Changhai , Ji Hongjuan , Liu Jianju , Shi Wei , Chen Zichun , Liang Chengzhi , Li Aihong 
Published: October 2021

Abstract
Rice blast is one of the most widespread and devastating diseases in rice production. Tremendous success has been achieved in identification and characterization of genes and quantitative trait loci (QTLs) conferring seedling blast resistance, however, genetic studies on panicle blast resistance have lagged far behind. In this study, two advanced backcross inbred sister lines (MSJ13 and MSJ18) were obtained in the process of introducing Pigm into C134S, and showed significant differences in the panicle blast resistance. One F2 population derived from the crossing MSJ13/MSJ18 was used to QTL mapping for panicle blast resistance using Genotyping by Sequencing (GBS) method. A total of 7 QTLs were identified, including a major QTL qPBR10-1 on chromosome 10 that explaining 24.21% of phenotypic variance with LOD scores of 6.62. Furthermore, qPBR10-1 was verified via the BC1F2 and BC1F3 population and narrowed to a 60.6-kb region with six candidate genes predicted, including two genes encoding exonuclease family protein, two genes encoding hypothetical protein, and two genes encoding transposon protein. The nucleotide variations and the expression patterns of the candidate genes were identified and analyzed between MSJ13 and MSJ18 through sequence comparison and RT-PCR approach, and results indicated that ORF1 and ORF2 encoding exonuclease family protein might be the causal candidate genes for panicle blast resistance in the qPBR10-1 locus.
The architecture and operating mechanism of a cnidarian stinging organelle
Authors: Gibson Matthew , Karabulut Ahmet , McClain Melainia , Rubinstein Boris , McKinney Sean 
Published: October 2021

Abstract
The stingers of jellyfish, sea anemones and other cnidarians, known as nematocysts, are remarkable cellular weapons used for both predation and defense1. Nematocysts are specialized organelles which consist of a pressurized capsule containing a coiled harpoon-like thread2. These structures are in turn built within specialized cells known as nematocytes3. When triggered4, the capsule explosively discharges, ejecting the coiled thread which punctures the target and rapidly elongates by turning inside out in a process called eversion5,6. Due to the structural complexity of the thread and the extreme speed of discharge, the precise mechanics of nematocyst firing have remained elusive7. Here, using a combination of live and super-resolution imaging, 3D electron microscopy and genetic perturbations, we define the step-by-step sequence of nematocyst operation in the model sea anemone Nematostella vectensis. This analysis reveals the complex biomechanical transformations underpinning the operating mechanism of nematocysts, one of the nature’s most exquisite biological micro-machines. Further, this study will provide insight into the form and function of related cnidarian organelles and serve as a template for the design of bioinspired microdevices.
The structure-specific endonuclease complex SLX4/XPF regulates Tus/Ter-induced homologous recombination
Authors: Scully Ralph , Elango Rajula , Panday Arvind , Lach Francis , Willis Nicholas , Duffey Erin , Smogorzewska Agata 
Published: October 2021

Abstract
Vertebrate replication forks arrested at an interstrand DNA crosslink (ICL) can engage the Fanconi anemia (FA) pathway of ICL repair. The FANCP product, SLX4, binds the FANCQ/XPF/ERCC4-ERCC1 endonuclease, which incises bidirectionally arrested forks to ‘unhook’ the ICL. The resulting double strand break (DSB) is repaired by homologous recombination (HR). Whether this mechanism operates at replication blocks other than ICLs is unknown. Here, we study the role of mammalian SLX4 in HR triggered by a site-specific, chromosomal DNA-protein replication fork barrier formed by the Escherichia coli-derived Tus/Ter complex. We identify an SLX4-XPF-mediated step that is required for Tus/Ter-induced HR but not for HR induced by a replication-independent DSB. We additionally identify a requirement for SLX4-XPF in DSB-induced ‘long tract’ gene conversion, a replicative HR pathway related to break-induced replication. Our work suggests that Tus/Ter-induced HR recapitulates the incision step of replication-coupled ICL repair, and that the full FA mechanism can process DNA-protein barriers for HR.
Prevalence and Determinants of Under-nutrition Among Children Under Five Years of Age in Afar Region, Ethiopia: Evidence From 2016 Ethiopian Demographic and Health Survey
Authors: Mengesha Damitie Kebede 
Published: October 2021

Abstract
BackgroundUndernutrition is one of the major public health concerns among infants and young children in the country. Childhood under-nutrition is widespread in low and middle-income countries. This study was initiated to assess the prevalence of under-nutrition and its associated factors among under-five children in Afar Region, Ethiopia. MethodsThe data for this study were extracted from the Ethiopian Demographic and Health Survey (EDHS) 2016. The information collected from 937 children born 5 years before the survey was considered in the analysis. A multivariable binary logistic regression analysis was used at a 5% level of significance to determine the individual- and community-level factors associated with childhood malnutrition.ResultsThe prevalence of stunting, underweight and wasting in Afar region were 41.1%, 36.2% and 17.7%, respectively. About 26.7% of children in Afar region were both stunting and underweight, 12.7% were both underweight and wasting, 7.6% were both stunting and wasting and only 7.0% of children had all the three under-nutrition conditions. Among the factors considered in this study, age of a child in months, anemia level, mothers’ BMI, household wealth index, size of child at birth, number of living children and place of residence were significantly associated with stunting, underweight and wasting in Afar Region. Conclusions﻿The prevalence of all stunting, underweight and wasting was relatively high. Undernutrition is one of the major public health concerns among children in Afar Region. The effect of these factors should be considered to develop strategies to reduce under-nutrition in the study area. Thus, intervention should be focused on improving the under-nutrition determinants of the children to improve the child's nutritional status and reduce child morbidity and mortality.
Hematopoietic Islands Mimicking Osteoblastic Metastases in Axial Skeleton
Authors: Goller Sophia Samira , Erber Bernd , Fink Nicola , Dürr Hans Roland , Knösel Thomas , Ricke Jens , Baur-Melnyk Andrea 
Published: October 2021

Abstract
Background. Hyperplasia of the hematopoietic bone marrow in the appendicular skeleton is common. Focal hematopoietic islands within the axial skeleton is a rare entity and can cause confusion with osteoblastic metastases. The purpose of this study was to describe the characteristic imaging findings in MRI and CT.Methods. We retrospectively analyzed the imaging findings of 14 hematopoietic islands of the axial skeleton in ten patients (nine females, median age= 65.5 years [range, 49-74]), who received both CT and MRI at the time of initial diagnosis between 2006 and 2020. In five cases CT-guided biopsy was performed to confirm the diagnosis, while the other five patients received long term MRI follow-up (median follow-up= 28 months [range, 6-96 months]). Diffusion-weighted imaging was available in three, chemical shift imaging in two, 18F fluorodeoxyglucose PET/CT in two and Technetium 99m skeletal scintigraphy in one of the patients.Results. All lesions were small (mean size=1.72 cm2) and showed moderate hypointense signals on T1- and T2-weighted MRI sequences. They appeared iso- to slightly hyperintense on STIR images and showed slight enhancement after gadolinium administration. To differentiate this entity from osteoblastic metastases, CT provides important additional information, as hematopoietic islands do not show sclerosis. Conclusions. Hematopoietic islands within the axial skeleton can occur and mimic osteoblastic metastases. However, the combination of MRI and CT allows for making the correct diagnosis.
Cardiac Device Implantation and Device Usage in Fabry and Hypertrophic Cardiomyopathy
Authors: Vijapurapu Ravi , Bradlow William , Leyva Francisco , Moon James C , Zegard Abbasin , Lewis Nigel , Kotecha Dipak , Jovanovic Ana , Hughes Derralynn , Woolfson Peter , Steeds Richard P , Geberhiwot Tarekegn 
Published: October 2021

Abstract
BackgroundFabry disease (FD) is a treatable X-linked condition leading to progressive cardiac disease, arrhythmia and premature death. We aimed to increase awareness of the arrhythmogenicity of Fabry cardiomyopathy, by comparing device usage in patients with Fabry cardiomyopathy and sarcomeric HCM. All Fabry patients with an implantable cardioverter defibrillator (ICD) implanted in the UK over a 17 year period were included. A comparator group of HCM patients, with primary prevention ICD implantation, were captured from a regional registry database. ResultsIndications for ICD in FD varied with 82% implanted for primary prevention based on multiple potential risk factors. In FD and HCM primary prevention devices, arrhythmia occurred more frequently in FD over shorter follow-up (HR 4.2,p<0.001). VT requiring therapy was more common in FD (HR 4.5,p=0.002). Immediate shock therapy for sustained VT was also more common (HR 2.5,p<0.001). There was a greater burden of AF needing anticoagulation and NSVT in FD (AF: HR 6.2,p=0.004, NSVT: HR 3.1,p<0.001). ConclusionThis study demonstrates arrhythmia burden and ICD usage in FD is high, suggesting that Fabry cardiomyopathy may be more ‘arrhythmogenic’ than previously thought. Existing risk models cannot be mutually applicable and further research is needed to provide clarity in managing Fabry patients with cardiac involvement.