bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationships between apparent diffusion coefficient (ADC) histogram analysis parameters and PD-L 1-expression in head and neck squamous cell carcinomas: a preliminary study
Authors: Meyer Hans-Jonas , Höhn Anne Kathrin , Surov Alexey 
Published: January 2021

Abstract

Background
Immunotherapy has become a cornerstone of the modern cancer treatment. It might be crucial to predict its expression non-invasively by imaging. The present study used diffusion-weighted imaging (DWI) quantified by whole lesion apparent diffusion coefficient (ADC) values to elucidate possible associations with programmed cell death ligand 1(PD-L1) expression in head and neck squamous cell cancer (HNSCC).

Patients and methods
Overall, 29 patients with primary HNSCC of different localizations were involved in the study. DWI was obtained by using a sequence with b
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values of 0 and 800 s/mm2 on a 3 T MRI. ADC values were evaluated with a whole lesion measurement and a histogram approach. PD-L1 expression was estimated on bioptic samples before any form of treatment using 3 scores, tumor positive score (TPS), immune cell score (ICS), and combined positive score (CPS).

Results
An inverse correlation between skewness derived from ADC values and ICS was identified (r = -0.38, p = 0.04). ADCmax tended to correlate with ICS (r = -0.35, p = 0.06). Other ADC parameters did not show any association with the calculated scores.

Conclusions
There is a weak association between skewness derived from ADC values and PD-L1 expression in HNSCC, which might not be strong enough to predict PD-L1 expression in clinical routine. Presumably, ADC values are more influenced by complex histopathology compartments, comprising cellular and extracellular aspects of tumors than only of a single subset of tumor associated cells.
Radial Flap in Reconstructions of the Hand - Case Series Study
Authors: Vulovic Dejan , Kozarski Jefta , Curcic Zeljko , Stepic Nenad , Vucetic Milos , Rakic Dejana , Vulovic Tatjana 
Published: January 2021

Abstract
Radial forearm flap is an axial flap that has become an important technique in reconstructive surgery as a free flap or as a pedicled flap. Defects of the skin and other tissues on the hand are very common and most often they are work-related injuries. In deep defects, flap must be used, as well as in reconstruction of the amputated thumb. There are many flaps that provide adequate soft tissue coverage for the hand. Therefore, the aim of this paper is to present the results of the use of radial forearm flap in various reconstructions on the hand. The retrospective study included 35 patients who underwent reconstruction with radial forearm flaps due to defects of the skin and other tissues on the hand, in the period 1997-2019. Results and complications of the surgery were analyzed. The functional and aesthetic outcome was assessed using Michigan Hand Outcome Qusteionnarire. All patients were followed for a minimum of 1 year. Fasciocutaneous flap was the most commonly used (65.71%), followed by adiposofascial (20%) and osteocutaneous (14.29%). The size of the fasciocutaneous flap ranged from 2.2×3.1cm to 9×13.5cm. The majority of donor sites were closed with split-thickness skin grafts (56.52%), and less frequently with direct suture, local skin flap, and full-thickness skin graft. There were no complete flap losses in the study. Marginal necrosis was noted in 8.57%, and graft failure at the donor site in 14.29%. Secondary surgical procedures were performed in 13 patients. The functional-aesthetic result of the operation, based on the MHQ score, ranged from 31 (1/35) to 130 points (3/35). The ultimate aim of hand reconstruction is to restore sufficient function and form, also, closing the wound within three days following the injury is desirable. Meticulous intraoperative dissection of radial flap and early physical therapy after surgery are mandatory. The radial flap is a suitable method, especially for large and more distal skin defects on the hand, and a very good method for thumb reconstruction.
PENGARUH ROE DAN NPM TERHADAP HARGA SAHAM PERUSAHAAN SUBSEKTOR OTOMOTIF DAN KOMPONEN YANG TERDAFTAR DI BEI PERIODE 2014-2019
Authors: Safitri Vina Tiara , Sulistiyo Hari 
Published: January 2021

Penelitian ini bertujuan untuk mengetahui pengaruh Return On Equity (ROE) dan Net Profit Margin (NPM) terhadap harga saham perusahaan subsektor otomotif dan komponen yang terdaftar di Bursa Efek Indonesia periode 2014-2019. Pengujian hipotesis dalam penelitian ini menggunakan Analisis Regresi Linear Berganda.Populasi dalam penelitian ini 13 perusahaan, dengan sampel 11 perusahaan, sampel yang dipilih menggunakan purposive sampling. Hasil dari penelitian ini menunjukan bahwa Return On Equity dan Net Profit Margin terhadap harga saham tidak memiliki pengaruh secara parsial maupun simultan terhadap harga saham.
Polityczny wymiar dialogu Kościoła katolickiego z judaizmem w wybranych dokumentach Kurii Rzymskiej
Authors: Górzna Sylwia 
Published: January 2021

Punktem wyjścia do rozważań były dokumenty Kurii Rzymskiej, zwłaszcza Komisji Stolicy Apostolskiej do Spraw Stosunków Religijnych z Judaizmem, działającej w ramach Papieskiej Rady ds. Popierania Jedności Chrześcijan, które podejmują problematykę dialogu międzyreligijnego, przede wszystkim dialogu katolicko-żydowskiego. W niniejszym artykule zaprezentowano ich polityczne aspekty, do których możemy zaliczyć m.in.: formy dialogu międzyreligijnego, współpraca wyznawców obu religii na rzecz sprawiedliwości i pokoju, przeciwstawianie się antysemityzmowi i wszelkim formom dyskryminacji. Na- wiązano do dokumentów Soboru Watykańskiego II (1962–1965), zwłaszcza do Deklaracji o stosunku Kościoła do religii niechrześcijańskich Nostra aetate, która stanowiła istotny zwrot w historii stosunków katolicko-żydowskich
A Gestão da Qualidade nas Empresas Go Digital
Authors: Sandes Maria Luiza Silva , De Oliveira Luciana Bazante 
Published: January 2021

Diante dos avanços tecnológicos ocorridos na última década e da transformação digital em curso, empresas tradicionais cujas presenças no mercado já eram consideradas como consolidadas, passaram a investir na adaptação de sua mentalidade de trabalho e inovação de seus processos produtivos, a fim de sintonizar-se com as tendências modernas e as novas exigências dos clientes, para manter-se em condições de concorrência com as recém-chegadas empresas be digital. Nesse contexto, a norma ISO 9001:2015 desempenha papel fundamental no processo de preparação das empresas go digital, tendo como ponto de partida a busca pela melhoria contínua, por meio da aplicação dos seus requisitos. Ao mesmo tempo em que auxilia na estruturação da mudança para realidade do mindset digital, a gestão da qualidade atua na manutenção dos padrões de fornecimento dos produtos/serviços. Este trabalho consiste em um levantamento das etapas mais comuns da transformação digital e uma análise dos requisitos da norma que podem auxiliar cada etapa, bem como sugestões de aplicação.
Palavras-Chave: be digital; ISO 9001:2015; go digital; mindset digital
Aplicação de Ferramentas da Qualidade para Análise e Solução de Não Conformidades Em Uma Indústria de Alumínio
Authors: Tássia Andrielly , De Oliveira Luciana Bazante 
Published: January 2021

As ferramentas da qualidade são recursos essenciais para a melhoria contínua de processos e produtos, visto que as organizações buscam cada vez mais se manterem competitivas no mercado. Por serem versáteis, as ferramentas podem ser aplicadas em diversas situações, contribuindo para a coleta, análise e tratamento de informações. Este artigo foi elaborado com base em uma intervenção realizada em uma indústria de alumínio, com a aplicação das ferramentas da qualidade na análise de produtos não conformes, com o intuito de reduzir o número de reclamações de clientes por problemas relativos à variações na qualidade. Após a aplicação das ferramentas na análise e tratamento das não conformidades em produtos, verificou-se a redução do número de reclamações de clientes por não conformidades, atestando que a implantação das ferramentas da qualidade contribuiu para uma melhoria significativa nos produtos.

Palavras-Chave: Ferramentas da qualidade; Indústria de alumínio; Não conformidades.
STUDY OF THE INFLUENCE OF THE STRUCTURE OF 1,3-DIALKYLIMIDAZOLIUM IONIC LIQUIDS ON THE ELECTRICAL CONDUCTIVITY OF THEIR SOLUTIONS IN ACETONITRILE
Authors: Журавлев Олег Евгеньевич , Юлмасов Глеб Сергеевич , Суратова Екатерина Сергеевна , Ворончихина Людмила Ивановна 
Published: January 2021

Авторами работы получены ионные жидкости с катионом 1,3-диалкилимидазолия и неорганическими анионами. Проведены исследования электропроводности их растворов в ацетонитриле. Методом Ли-Уитона рассчитаны константы ионной ассоциации K, предельная молярная электрическая проводимости (λ) и энергия Гиббса ассоциации (ΔG) в растворах.
The authors of the work obtained ionic liquids with 1,3-dialkylimidazolium cation and inorganic anions. Studies of the electrical conductivity of their solutions in acetonitrile have been carried out. The Li-Wheaton method was used to calculate the ion association constants K, the limiting molar electrical conductivity (λ), and the Gibbs association energy (ΔG) in solutions.
STUDYING MORPHOLOGY OF SUSPENSIONS BY THE METHOD OPTICAL SPECTROSCOPY
Authors: Маркова Алена Игорьевна , Ярусов Максим Вадимович , Хижняк Светлана Дмитриевна , Пахомов Павел Михайлович 
Published: January 2021

Методом оптической спектроскопии (УФ, видимая и ИК области спектра) исследованы две суспензии: вазелиновое масло (ВМ) наполненное слюдой и BaSO различной концентрации. Разработанный метод основан на анализе рассеивающей компоненты электромагнитного излучения, проходящего через образец, позволяющий определить средний размер и распределение рассеивающих частиц по размерам. Установлено, что с увеличением концентрации наполнителя частицы агрегируют, вследствие чего средний размер частиц увеличивается. Результаты, полученные спектроскопическим методом, хорошо согласуются с данными оптической микроскопии.
Two suspensions were studied by optical spectroscopy (UV, visible, and IR): vaseline oil (VM) filled with mica and BaSO of different concentrations. The developed method is based on the analysis of the scattering component of electromagnetic radiation passing through the sample, which makes it possible to determine the average size and size distribution of scattering particles. It was found that with increasing filler concentration, the particles aggregate, resulting in an increase in the average particle size. The results obtained by the spectroscopic method are in good agreement with the optical microscopy data.
MECHANISM OF HYDROCHEMICAL OXIDATION OF HEAZLEWOODITE IN NITRIC ACID
Authors: Пичугина Анна Игоревна , Гончар Дарья Дмитриевна 
Published: January 2021

В работе представлена математическая модель гидрохимического окисления хизлевудита в разбавленных растворах азотной кислоты. Дана физико-химическая интерпретация основных кинетических характеристик процесса растворения: константа скорости и эффективная энергия активации. Установлены режимы взаимодействия хизлевудита с азотной кислотой, выявлены вероятные лимитирующие стадии. По наблюдаемым кинетическим закономерностям при моделировании процесса, предложен механизм гидрохимического окисления хизлевудита.
The paper presents a mathematical model of the hydrochemical oxidation of heazlewoodite in dilute solutions of nitric acid. A physicochemical interpretation of the main kinetic characteristics of the dissolution process is given: the rate constant and the effective activation energy. The modes of interaction of heazlewoodite with nitric acid have been established, and probable limiting stages have been identified. According to the observed kinetic regularities in modeling the process, a mechanism for the hydrochemical oxidation of heazlewoodite has been proposed.
Maria Junqueira Schmidt: uma intelectual católica em diálogo com a Escola Nova
Authors: Almeida Orlando Evelyn de 
Published: January 2021

Este artigo aborda a trajetória da educadora Maria Junqueira Schmidt, como uma intelectual católica e forte defensora da pedagogia nova alinhada ao catolicismo. Suas ações dão a ver modos de apropriação dos enunciados da Escola Nova a partir de suas experiências de formação na Europa quanto nos EUA, introduzidas no Brasil no ensino de línguas vivas, designadamente no ensino de francês. Notícias de jornais e relatórios de viagens, publicados na imprensa periódica, foram as principais fontes mobilizados nesta pesquisa, indicativas dos modos de apropriação da referida educadora. Pode-se dizer que, a partir da militância como intelectual e educadora católica, Maria Junqueira Schmidt inseriu-se e afirmou-se no campo da produção intelectual do país, tendo a educação como seu lugar privilegiado de fala.
Deteksi Limfosit Plasma Biru pada Citra Darah untuk Diagnosa Pendukung pada Kasus Demam Berdarah Dengue
Authors: AULIA SUCI , HADIYOSO SUGONDO 
Published: January 2021

ABSTRAKDemam Berdarah Dengue (DBD) adalah salah satu penyakit mematikan yang disebabkan oleh virus dengue sehingga diagnosis dini DBD sangat penting dilakukan. Secara umum, diagnosis dini DBD dilakukan melalui pemeriksaan trombosit namun pemeriksaan ini tidak spesifik. Salah satu uji klinis lainnya yang dapat dilakukan untuk diagnosis dini DBD adalah deteksi limfosit plasma biru (LPB) melalui pencitraan sel darah. Oleh karena itu, pada studi ini diusulkan metode deteksi LBP secara otomatis pada citra mikroskopis darah. Data dikumpulkan dari pasien dengue dan subjek normal. Pada studi ini digunakan 20 gambar dataset yang terdiri dari 10 gambar terinfeksi dengue dan 10 gambar limfosit biasa sebagai kondisi normal. Ekstraksi ciri dilakukan dengan filter Gabor dan kemudian validasi dilakukan dengan K-Nearest Neigbor (K-NN) dan 5-fold cross validation. Dari pengujian yang dilakukan diperoleh akurasi deteksi tertinggi sebesar 90%, dimana dicapai menggunakan metode Cosine K-NN. Hasil studi ini diharapkan dapat digunakan dalam menunjang penegakan diagnosa penyakit dengue.Kata kunci: demam berdarah dengue, deteksi, limfosit, K-NN ABSTRACTDengue Hemorrhagic Fever (DHF) is a deadly disease caused by the dengue virus, so early diagnosis of DHF is very important. Commonly, early diagnosis of dengue fever is done through a platelet examination, but this examination is not specific. One of the other clinical tests that can be done for early diagnosis of DHF is detection of blue plasma lymphocytes (LBP) through blood cell imaging. Therefore, this study proposes an automatic LBP detection method on microscopic blood images. Data were collected from dengue patients and normal subjects. A total of 20 images were analyzed in this study consisting of 10 images infected with dengue and 10 images of normal lymphocytes as normal conditions. Feature extraction was carried out with the Gabor filter and then the validation was carried out with K-Nearest Neigbor (K-NN) and 5-fold cross validation. From the tests conducted, the highest detection accuracy is 90%, which is achieved using the Cosine K-NN method. The results of this study are expected to be used in supporting the diagnosis of dengue disease.Keywords: Dengue hemorrhagic fever, detection, lymphocytes, K-NN
The Adultification of the Youth Justice System: The Victorian Experience
Authors: Antolak-Saper Natalia 
Published: January 2021

In early 2018, an Inquiry into Youth Justice Centres in Victoria (Inquiry) found that a combination of a punitive approach to youth justice, inadequate crime strategies, and a lack of appropriately trained and experienced staff at youth justice centres, greatly contributed to the hindrance of the rehabilitation of young persons in detention in Victoria, Australia. In addition to identifying these challenges, the Inquiry also determined that the way in which young offenders have been described by politicians and portrayed in the media in recent times, has had a significant impact on shaping youth justice policies and practices. This article specifically examines the role of the media in the adultification of the Victorian youth justice system. It begins with a historical examination of youth justice, drawing on the welfare model and the justice model. This is followed by a discussion of the perception and reality of youth offending in Victoria. Here, it is demonstrated that through framing, the media represents heightened levels of youth offending and suggests that only a ‘tough on crime’ approach can curb such offending; an approach that has been adopted by the Victorian State Government in recent years. Finally, the article considers how recent youth justice reforms are examples of adultification, and by not adequately distinguishing between a child and adult offender, these reforms are inconsistent with the best interests of the child.
Pencegahan Tindak Kekerasan Terhadap Perempuan Perspektif Al-Qur’an
Authors: Dwijayanti Febri 
Published: January 2021

Penelitian ini dilatarbelakangi oleh realitas yang memprihatinkan, yaitu banyaknya perempuan yang menjadi korban dalam tindak kekerasan rumah tangga. Tindakan tersebut terjadi karena seorang suami merasa bahwa dirinya berhak melakukan apapun terhadap istrinya. Perbedaan yang terjadi antara perempuan dan laki-laki bukanlah tindakan dari diskriminasi. Perbedaan tersebut tidak digunakan untuk meninggikan ataupun merendahkan salah satu makhluk. Salah satu faktor yang memicu tindakan kekerasan tersebut berkaitan dengan bagaimana cara suami dalam menyelesaikan permasalahan. Sedangkan sebagai perempuan kebanyakan mereka menerima segala perlakuan dengan pasrah dan mengalah. Oleh karena itu penulis termotivasi untuk mengkaji tentang tafsiran beberapa ayat yang berkaitan dengan kekerasan terhadap perempuan agar dari penafsiran tersebut dapat ditemukan pencegahannya. Pendekatan penelitian ini menggunakan pendekatan fenomenologi maka, sumber data yang digunakan dalam penulisan skripsi ini adalah fenomena yang terjadi dalam kehidupan rumah tangga dengan menggunakan penelitian kepustakaan (library research). Sedangkan metodologi yang digunakan adalah metode tematik dengan membahas beberapa ayat sesuai dengan tema yang ada di dalam al-Qur’an. Hasilnya penulis menemukan pencegahan dapat dilakukan pada masa awal perkawinan dengan memberikan wejangan dari pihak orang tua serta bagi kedua belah pasangan harus memahami sifat dan kepribadian masing-masing. Kekerasan dalam rumah tangga dapat diatasi pada masa awal sebelum perkawinan. Suami harus memiliki pemikiran yang positif bahwasanya istri adalah titipan Tuhan yang harus yang harus diberikan rasa tanggung jawab, diperlakukan dengan baik seperti dalam awal surah An-Nisa ayat 34 bahwasanya laki-laki adalah pemimpin keluarga. Serta dalam kehidupan rumah tangga harus senantiasa menumbuhkan rasa cinta dan kasih sayang seperti dalam surah Ar-Rum ayat 21.
EFEKTIFITAS KEPEMIMPINAN DALAM MEMOTIVASI PUSTAKAWAN DI LINGKUNGAN PERPUSTAKAAN
Authors: Syamsuddin Syamsuddin 
Published: January 2021

ABSTRAK
Tulisan ini bertujuan untuk mengetahui bagaimana peran pemimpin dalam memotivasi pusakawan sebagai pegawai professional di lingkungan perpustakaan.Tulisan ini memfokuskan pada bagaimana pola kepemipinan pemimpin dalam motivasi pustakawan terkait dengan kegiatan kepustakawanan, dan apa saja hambatan-hambatan yang dihadapi dalam memotivasi pustakawan.
Strategi Pengembangan Content Based Video Retrieval Di Perpustakaan Sekolah Tinggi Multi Media MMTC Yogyakarta
Authors: Wahyuni Sri 
Published: January 2021

ABSTRACT

Introduction One of the efforts to provide the best service for users is by developing innovative library services. One of them is by developing a video content-based library collection. MMTC Yogyakarta Multi Media College Library has developed a video content-based information retrieval system. It is hoped that by utilizing this video content-based STKI, users will be helped and get accelerated information in finding the material needed, especially searching for material in video files.
Data Collection Method. In this paper the writer uses qualitative research with a library research approach, while the data analysis uses content analysis techniques. This method the authors use to observe and analyze an information system.
Results and Discussions. In developing a Content Based Video Retrieval strategy in the MMTC Yogyakarta Multi Media High School Library, it begins with identifying user needs, creating a system design, evaluating the system design, pouring the system design into a programming language, testing the system, evaluating the system and using it. Then, the authors also provide an overview of the development of the STKI by conducting a SWOT analysis. Based on the macro analysis, the opportunity and threat variables will be formulated, while the internal analysis will formulate the strength and weakness variables. The last stage is the STKI analysis, while the stages are: complete definition, problem analysis, needs analysis, logic design and needs analysis.
Conclusions. In the Content Based Video Retrieval development strategy at the MMTC Yogyakarta Multi Media College Library, there are several things that need to be considered in the development of an information retrieval system, including: User needs, development budget (budget), human resources, support from leaders and facilities (software and hardware) and IT infrastructure (internet network). The development of the STKI should begin with identifying user needs and conducting a SWOT analysis to determine the strengths and weaknesses of the system, as well as the goal so that the system can be optimally empowered by users.

Keywords: Library, Information Retrieval System, Video Content
PEMAHAMAN HADIS NAHDLATUL ULAMA TENTANG HUKUM SALAM LINTAS AGAMA
Authors: Haris Abdul 
Published: January 2021

In the Indonesian context, the understanding of hadith is also carried out by various Muslim communities in Indonesia which in this case are the Nahdlatul Ulama community or abbreviated as NU. In connection with this, lately there was a polemic about the practice of greeting from various religious traditions carried out by officials. Along with the diversity of society, the pros and cons are inevitable. Discussions in the public room were increasingly busy responding to the issue. In this condition, the East Java Nahdlatul Ulama (PWNU) Regional Board was called to attend to study it scientifically as part of his sermon to the people, nation and state. The author tries to reveal about how the general understanding of the hadith? And how is the understanding of the hadith among the Nahdlatul Ulama religious community. In this case the hadith about greetings across religions in the context of national and state life.

Dalam konteks Indonesia, pemahaman terhadap hadis juga dilakukan oleh berbagai komunitas muslim di Indonesia yang dalam hal ini adalah komunitas Nahdlatul Ulama atau disingkat NU. Bekaitan dengan hal itu, belakangan terjadi polemik praktek pengucapan salam dari berbagai tradisi agama yang dilakukan oleh para pejabat. Seiring kemajemukan masyarakat, pro kontra pun tidak terhindarkan. Diskusi diruang publik pun semakin ramai merespon isu tersebut. Dalam kondisi demikian Pengurus Wilayah Nahdlatul Ulama (PWNU) Jawa Timur terpanggil hadir untuk mengkajinya secara ilmiah sebagai bagian khidmahnya kepada masyarakat, bangsa dan negara. Penulis berusaha mengungkap tentang bagaimanakah pemahaman hadis secara umum? Serta bagaimana pemahaman hadis dikalangan komunitas keagamaan Nahdlatul Ulama. Dalam hal ini hadis tentang salam lintas agama dalam konteks kehidupan berbangsa dan bernegara.