bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring the cost–carbon trade‐off in using a mixed fleet of hydrogen trucks and diesel trucks
Authors: Guo Siqiang , Kutanoglu Erhan , Goodarzi Shadi , Singh Manjeet 
Published: December 2024

AbstractHydrogen trucks (HTs) offer promising potential for decarbonizing the transportation sector. Based on current technologies, they have significant advantages over electric trucks (ETs) in terms of range, refueling time, and performance in cold conditions. However, HTs are costly, and there are insufficient hydrogen refueling stations (HRSs). Gradually integrating HTs into the existing diesel truck (DT) fleet is a practical approach for many freight logistics companies. In this article, we formulate a mathematical model to route a mixed fleet of HTs and DTs, and we propose an algorithm called the curve descent search (CDS) to generate the Pareto set based on cost and carbon emissions. We find that CDS can generate better Pareto sets compared to existing algorithms in the literature. We use CDS to comprehensively explore the cost–carbon trade‐off in using a mixed fleet. This question differentiates our study from previous research and is motivated by discussions with one of the largest third‐party logistics companies in North America. Detailed experiments reveal important managerial insights, such as: (1) Achieving a significant reduction in carbon emissions (e.g., a 30% reduction compared to the current diesel fleet) does not need a very dense refueling infrastructure; (2) The cost–carbon trade‐off for mixed fleets is relatively insensitive to variations in customer density and demand, suggesting that HTs can be applicable across a wide range of scenarios (including different sectors or regions); and (3) Although ETs are cheaper to use compared to HTs, their shorter range limits their competitiveness in terms of decarbonization efficiency and customer service.
Whom You Connect With Matters: Innovation Collaboration Network Centrality and Innovative Productivity in Chinese Cities
Authors: Zhang Cui , Zhang Dandan , Pan Yu , Wang Yanzhen 
Published: December 2024

ABSTRACTThis paper introduces eigenvector centrality to capture partner heterogeneity and examines its impact on urban innovation. By constructing and empirically testing a co‐invention patent database of Chinese cities over the period from 2014 to 2018, we find that eigenvector centrality has a positive effect on urban innovation. Technology breadth and technology depth increases are two important underlying mechanisms. A counterfactual analysis shows that laggard cities with low levels of innovation can increase their innovative productivity by establishing collaborative links with other cities, especially with well‐connected cities, which indicates the potential gains from policies that improve the inter‐city innovation collaboration network structure. And this result is further confirmed by the comparative analysis of Erdos and Chifeng.
Status of robotic surgery in pediatric genitourinary tumors: A systematic review
Authors: Yadav Priyank , Alshammari Dheidan , Ahmad Ihtisham , Ansari Mohd S. , Gundeti Mohan S. 
Published: December 2024

AbstractInnovative surgical approaches are crucial in pediatric oncology to enhance treatment outcomes and minimize morbidity. Robotic‐assisted surgery (RAS) has shown promise in both surgical precision and recovery in pediatric patients. This systematic review aims to address this gap by examining the current role and impact of RAS in managing pediatric genitourinary tumors, focusing on its feasibility, safety, and patient outcomes. This review was registered with PROSPERO (CRD42023464820). We included studies involving pediatric patients undergoing RAS for genitourinary tumors, focusing on outcomes like conversion rates, resection completeness, and complications. Studies were identified through searches in PubMed, EMBASE, and Scopus until October 2023. Study quality and bias were assessed using ROBINS‐I for cohort studies and Joanna Briggs Institute tools for case reports and series. Of 2119 citations, 42 studies were included, comprising 29 case reports, five case series, and eight retrospective cohort studies. Robotic‐assisted renal surgeries were most common, with favorable outcomes in terms of resection completeness and low recurrence rates. Adrenal, bladder, and retroperitoneal surgeries also showed promising results, although rare instances required conversion to open surgery. Collaborative efforts and perioperative aids like intraoperative ultrasound and three‐dimensional modeling were crucial for success. This work is limited by the lack of large cohort studies and addressing the learning curve associated with these procedures. RAS shows promise in treating pediatric genitourinary tumors, offering precise resections and favorable outcomes, warranting further research and refinement.
Mindfulness and Voice Behaviour: A Diary Study of Ego Depletion and Work‐Related Self‐Efficacy Among Nurses
Authors: Yuan Xiaolong , Ding Qian , Yang Yongyong , Wang Feng , Li Xiujun , Li Jiameng , Shi Wendian 
Published: December 2024

ABSTRACTAimThis study examined how mindfulness affects voice behaviour by altering nurses' daily resource levels.BackgroundMindfulness is an essential personal resource; it can enhance the accumulation of resources and empower individuals to engage in adaptive resource regulation. This study suggests that on days when nurses' mindfulness is higher than average, they may accumulate more resources that facilitate their voice behaviour.DesignWe employed an intensive longitudinal design in the form of a daily diary. Participants were asked to complete both one‐time and daily surveys.MethodsWe collected data between March and September 2024, and 119 nurses were tracked over seven workdays. We tested the hypothesised relationships using a multilevel analysis.ResultsMindfulness was positively related to nurses' voice behaviour; this relationship was mediated by work‐related self‐efficacy (WRSE). Moreover, ego depletion and WRSE played a chain‐mediating role between mindfulness and nurses' voice behaviour.ConclusionMindfulness enhances nurses' voice behaviour as well as an individual's resource level and enables him/her to obtain more resources through voice behaviour.ImpactGiven the positive impact of mindfulness, we advocate for expanding mindfulness training for nurses to boost their resource levels and consequently encourage voice behaviour. In addition, given the mediating role of ego depletion and WRSE, we emphasise the importance of identifying and mitigating factors that contribute to nurses' ego depletion. Furthermore, we call for training on professional skills to be provided to enhance nurses' confidence in their abilities.Patient or Public ContributionThere are no patient or public contributions. This study did not involve patients or the public in the design and implementation process because it focused on investigating the work behaviour of nurses, where the involvement of patients and the public may not have been essential.
Are ADHD trajectories shaped by the social environment? A longitudinal study of maternal influences on the preschool origins of delay aversion
Authors: Chan Wendy W.Y. , Shum Kathy Kar‐man , Downs Johnny , Sonuga‐Barke Edmund J.S. 
Published: December 2024

BackgroundAttention‐deficit/hyperactivity disorder (ADHD) is commonly attributed to neuro‐cognitive deficits of genetic and/or prenatal/perinatal environmental origins. Sonuga‐Barke proposed an alternative formulation, suggesting that ADHD behaviors are functional expressions of delay aversion—a strong motivational disposition to avoid or escape negative affective states evoked by delay. It is hypothesized that the strength of this disposition, though neuro‐biologically rooted, is exacerbated by early negative social interactions during waiting‐related encounters. This paper reports findings from an initial proof‐of‐concept study that specifically tests this hypothesis in a nonclinical sample.MethodsPreschoolers (n = 112; mean age = 46.2 months) and their parents from London, UK, and Hong Kong participated in a longitudinal study. The Parent–Child Delay Frustration Task (PC‐DeFT) and two nonwaiting control tasks were administered at baseline. Children's performance, behavioral and emotional responses, and parents' reactions were observed. Teachers rated children's ADHD behaviors and delay aversion at baseline and follow‐up (12–18 months later).ResultsAt baseline, children's maladaptive performance and parental negative reactions during the PC‐DeFT were correlated with each other and with teacher ratings of ADHD and delay aversion. Negative parental reactions during the PC‐DeFT at baseline predicted an increase in teacher‐rated ADHD behaviors at follow‐up, but similar associations were not observed for baseline parental responses in the nonwaiting tasks. The increase in child ADHD symptoms associated with negative parental reactions at baseline was statistically mediated by delay aversion. These longitudinal effects were consistent across the UK and HK samples.ConclusionsThe findings provide the first evidence that parent's negative reactions to preschooler's attempts to manage delay are associated with increases in ADHD behaviors overtime, and linked to delay aversion increases. They underscore the potential significance of the early social environment as a contributor to developmental trajectory of ADHD behaviors. Future studies with clinical samples over an extended time‐frame using a range of different aversive environments (i.e. difficult tasks to complete) are indicated.
Interleukin‐37 promotes wound healing in diabetic mice by inhibiting the MAPK/NLRP3 pathway
Authors: Cui Qiaoli , Zhang Zhenming , Qin Lang , Teng Zhaolin , Wang Zhihong , Wu Wei , Fan Linling , Su Jing , Hao Yexuan , Qin Ji , Zhang Li , Wang Qi , Zhuang Yuan , Zheng Hangping , Zhang Shuo , Geng Xiang , Zhu Lei , Chen Yijian , Lu Bin , Li Yiming , Zhu Xiaoming 
Published: December 2024

ABSTRACTAims/IntroductionDiabetic foot ulcer (DFU) is a prevalent complication of diabetes characterized by heightened inflammation and impaired wound‐healing processes. Interleukin‐37 (IL‐37) is a natural suppressor of innate inflammation. Here, we aim to investigate the potential of IL‐37 in enhancing the healing process of diabetic wounds.Materials and MethodsThe skin samples of DFU and non‐diabetic patients during foot and ankle orthopedic surgery were collected. The IL‐37 transgenic mice (IL‐37Tg) were created using CRISPR/Cas‐mediated genome engineering. Mice were administered streptozotocin (STZ, 150 mg/kg) to induce a diabetic model. After 4 weeks, an equidistant full‐thickness excisional wound measuring 8 mm was created on the central back of each mouse and allowed to heal naturally. Body weight and blood glucose levels were measured weekly. The wound area was measured, and skin samples were collected on Day 10 for further Quantitative polymerase chain reaction (qPCR) and WB detection and RNA sequencing analysis.ResultsThe proinflammation cytokines such as TNF‐α and IL‐1β and the MAPK signaling pathway were significantly increased in the wound margin of DFU patients. Compared with diabetic mice, diabetic IL‐37Tg mice showed a significantly accelerated healing process. The enriched signaling pathways in RNA sequencing included cytokine–cytokine receptor interaction, TNF signaling pathway, and NOD‐like receptor signaling pathway. Through QPCR and WB detection, we found that IL‐37 could inhibit the activated MAPK and NOD‐like signaling pathway, reducing TNF‐α, IL‐1β, and NLRP3 expression in the diabetic wound.ConclusionsIL‐37 promotes skin wound healing in diabetic mice, providing a new possible target for treating diabetic wounds.
Elucidation of the clinical traits of diabetic chorea through a questionnaire survey of people with diabetic chorea from 59 Japanese hospitals
Authors: Arakawa Naoko , Aoyama Tomohisa , Suwanai Hirotsugu , Toda Gotaro , Takamoto Iseki , Okazaki Yukiko , Kadowaki Takashi , Yamauchi Toshimasa 
Published: December 2024

ABSTRACTAimsDiabetic chorea refers to sudden involuntary movements developing in people with diabetes mellitus and is known to occur mainly in those with severe hyperglycemia. We conducted a questionnaire survey of case‐reporting facilities in Japan to elucidate their clinical characteristics.MethodsWe searched the PubMed and Ichushi databases for case reports published from January 1, 2012, to December 31, 2017, using “diabetes” and “chorea” as keywords, and sent a questionnaire to the reporting institutions.ResultsData from a total of 64 cases were included in this study. While most cases had severe hyperglycemia at the onset of diabetic chorea, hypoglycemia/improvement of the plasma glucose served as the trigger for the symptom in 14 cases (21.9%). The Early Remission Group (≤6 months) consisted of 39 cases (60.9%), while the Prolonged Partial Remission Group (>6 months) included 25 cases (39.1%). In the Prolonged Partial Remission Group (>6 months), there were more cases with widespread involuntary movement symptoms, a higher number of cases exhibiting typical imaging findings, and a greater incidence of chorea onset after the initiation of antidiabetic treatment, including hypoglycemia.ConclusionsMost reported cases of diabetic chorea in Japan were elderly persons with type 2 diabetes mellitus and severe hyperglycemia, although there were also some cases in which the symptom developed in the setting of hypoglycemia. It has been suggested that rapid plasma glucose correction and hypoglycemia might be associated with the risk of development and prognosis of diabetic chorea.
Antimicrobial Activity of Thyme, Olive Oil, and Their Nanoemulsions Against Cronobacter Sakazakii: In Vivo Application as Natural Food Preservatives in Tallaga Cheese
Authors: Kamal Sahar Mahmoud , Elsherif Walaa Mahmoud , Valero Antonio , Faried Alshimaa Mohammed 
Published: December 2024

ABSTRACTTallaga cheese is the most popular type of white soft cheese in Egypt. Cronobacter sakazakii is an opportunistic foodborne pathogen that poses a threat to the health of almost every age group, with a particular emphasis on neonates and infants. Essential oils (EOs), such as olive oil and thyme oil, exhibit a broad‐spectrum antibacterial effect. However, few studies have investigated the antibacterial activity of these EOs and their formulated nanoemulsions (NEs)—olive oil nano‐emulsions (ONE) and thyme oil nano‐emulsions (TNE)—on C. sakazakii in cheese to date. The purpose of this study was to investigate the inhibitory effects of these EOs and their NEs on the development of C. sakazakii during the processing and storage of Tallaga cheese. Additionally, the organoleptic properties of the resulting cheese were evaluated. Herein, ONE and TNE were prepared and characterized using a zetasizer and transmission electron microscopy (TEM). Furthermore, the minimum inhibitory concentrations (MICs) of EOs and NEs were determined using well diffusion assay. Fresh buffalo's milk for the elaboration of Tallaga cheese was inoculated with C. sakazakii at a concentration of 6 log CFU/mL, along with the addition of MICs of either EOs or NEs. The obtained results showed that the MICs were 15 mg/mL (v/v) for either olive oil, thyme oil, ONE and TNE with diameter inhibition zones of 10.3 ± 0.5, 13.3 ± 1.7, 12.3 ± 0.5, and 16 ± 0.8 mm, respectively. In addition, NEs exhibited high antibacterial activities against C. sakazakii in comparison to pure EOs. Particularly, the strongest antibacterial effect toward C. sakazakii was reported with TNE during manufacturing and storage of Tallaga cheese. Overall, these results suggest that thyme and its NEs have the potential to prevent bacterial contamination by C. sakazakii in the dairy industry.
Judicial Reform and Banks Credit Risk Exposure*
Authors: Canzian Giulia , Ferrara Antonella Rita 
Published: December 2024

AbstractThe aim of this paper is to examine the impact of the Judicial System Reform, which was introduced in Italy in 2012, on the efficiency of the judicial system and the exposure of banks to credit risk in terms of Non‐performing loans. To this end, we apply a difference‐in‐differences approach, using a dataset that covers annual judicial proceedings from 2010 to 2017, supplemented by bank balance sheet data. Our findings indicate that the reform had a detrimental effect on both judicial efficiency and the NPL ratio. The negative impact is especially pronounced in courts that were previously more efficient, suggesting that the court mergers may have resulted in diseconomies of scale.
Level of Information and Awareness About Colorectal Cancer and Its Screening Program in Türkiye: A Community‐Based Cross‐Sectional Study
Authors: ALPTEKİN Hatice Merve , KÜÇÜKKAYA Burcu 
Published: December 2024

ABSTRACTObjectiveColorectal cancer (CRC) has high mortality if it is detected in advanced stages, persons can lower their risk of CRC by adopting a healthy lifestyle that may lead to prevention. Screening is the most powerful public health tool to reduce mortality, considering the challenges of making substantial lifestyle changes or implementing widespread primary prevention strategies to lower the risk of CRC. This study aims to find out the levels of information and awareness about CRC and its screening program in individuals living in Türkiye.DesignThis study was a community‐based cross‐sectional.SampleThis study was performed from November 2019 to November 2022 with a web‐based survey circulated through social media and communication platforms. The research was conducted with 4146 participants.MeasurementsThe “Survey Form” was used in the data collection. Descriptive statistics and logistic regression were used in the data analysis.ResultsThe study found that 43.3% of participants had information about CRC and its screening program. Among all participants, 94.7% had never undergone CRC screening, and 55.6% were aware of a CRC awareness month. The study also revealed that participants who were knowledgeable about CRC screening were more likely to have a family history of cancer, a personal history of cancer, prior awareness of CRC, and previous information about the disease. Additionally, they were more likely to have undergone CRC screening before and to believe that CRC screening is necessary.ConclusionIt was found that the majority of participants had no information on CRC and its screening program and never underwent CRC screening before. More studies should be performed to find out the factors negatively affecting the participation of individuals in the CRC screening program
UV‐A photodegradation of vanillin in aqueous solutions: Direct photolysis and photosensitized degradation
Authors: Fernandez Heryerli , Niederst Leo , Joyeux Cécile , Allonas Xavier , Lorente Carolina 
Published: December 2024

AbstractPhototoxicity of skin due to the application of skincare products or fragrances is increasing from day to day, since a lot of natural extracts, with low or no toxicity in the dark, are being used in the skin exposed to solar radiation. In particular, the use of 4‐hydroxy‐3‐methoxy benzaldehyde, known as vanillin, in the pharmaceutical, food, and cosmetic industries has increased in the last years. This compound is generally considered as safe for humans, and it has been used in a wide range of applications. Significant beneficial properties, such as antioxidant, anticancer, antimicrobial, among others, have been described for vanillin, along with low toxicity. However, although vanillin is used as an ingredient in cosmetic formulations that are applied to the skin, there are few studies on the photochemistry of vanillin degradation. The degradation of vanillin in aqueous solutions exposed to UV‐A radiation (365 nm), both by direct absorption and by means of a photosensitized mechanism, was evaluated in different experimental conditions. On the bases of the experimental results, direct photodegradation of vanillin seems unlikely; however, photosensitized degradation of vanillin was observed in the presence of pterin, and vanillin dimers (6,6‐dihydroxy‐5,5‐ dimethoxy‐[1,1‐biphenyl]‐3,3‐dicarboxaldehyde) were detected as products. The mechanistic analysis indicates that the long‐lived pterin triplet excited state is responsible of vanillin degradation, while the contribution of reactive oxygen species, such as superoxide anion, hydrogen peroxide, or singlet oxygen, is negligible. The thermodynamic feasibility of the potential reactions involved in the degradation mechanism was evaluated with the Rehm–Weller equation. Considering both the thermodynamic and kinetic evidence, we proposed a mechanism for the photosensitized degradation of vanillin.
Securing a Future in Nonmetropolitan Areas: Community and Family Influences on Young Adults' Intentions to Stay for Employment☆
Authors: Choi Ha Young , Kramer Karen Z. 
Published: December 2024

AbstractThis study examines how community perceptions, family‐related factors, and other psychosocial factors collectively shape young adults' intentions to stay in their nonmetropolitan communities for employment. Research on nonmetropolitan populations' intentions to stay has increasingly highlighted community factors, including perceptions of the community and social connections. However, perceptions of the community have often been studied linearly and researchers have overlooked the multidimensional nature of employment decisions. Thus, this study conducted a latent profile analysis of 513 nonmetropolitan young adults and identified four distinct profiles: positive perceptions of social and professional characteristics (38.79%), positive perceptions of overall community characteristics (35.28%), positive perceptions of long‐term life planning characteristics (15.79%), and negative perceptions of overall community characteristics (10.14%). Path analyses indicated that community perception profiles, characterized by more positive perceptions of family‐friendliness and enjoyment of an active social and professional life, are associated with greater intention to obtain or retain local employment in a nonmetropolitan community. The findings are mediated by the effects of embeddedness within a community and organization. Family support also plays a crucial role in job seekers' intentions to stay for employment. They also value their own perceptions of fewer barriers to staying in nonmetropolitan organizations. These findings provide policy implications for attracting and retaining young nonmetropolitan workers by aligning their aspirations with community, work, and social characteristics.
Henipaviruses: epidemiology, ecology, disease, and the development of vaccines and therapeutics
Authors: Spengler Jessica R. , Lo Michael K. , Welch Stephen R. , Spiropoulou Christina F. 
Published: December 2024

SUMMARY
Henipaviruses were first identified 30 years ago and have since been associated with over 30 outbreaks of disease in humans. Highly pathogenic henipaviruses include Hendra virus (HeV) and Nipah virus (NiV), classified as biosafety level 4 pathogens. In addition, NiV has been listed as a priority pathogen by the World Health Organization (WHO), the Coalition for Epidemic Preparedness Innovations (CEPI), and the UK Vaccines Research and Development Network (UKVN). Here, we re-examine epidemiological, ecological, clinical, and pathobiological studies of HeV and NiV to provide a comprehensive guide of the current knowledge and application to identify and evaluate countermeasures. We also discuss therapeutic and vaccine development efforts. Furthermore, with case identification, prevention, and treatment in mind, we highlight limitations in research and recognize gaps necessitating additional studies.