bluuebunny/crossref_metadata_2025_split huggingface dataset:
METODE TRIPLE EXPONENTIAL SMOOTHING TIPE BROWN PADA PERAMALAN PRODUKSI PADI PROVINSI JAWA TENGAH
Authors: Kurniawati Meta 
Published: December 2021

Paddy is one of the staple food crops that almost all Indonesians consume every day. Central Java Province is one of the national food buffer provinces, therefore a model is needed to predict the amount of paddy production in Central Java Province for the future. The amount of paddy production in Central Java Province is not constant and fluctuates every year, so the one-parameter Triple Exponential Smoothing model of the Brown type is used to predict the amount of paddy production in Central Java Province. Based on the results of the analysis of the data, it was obtained that the one-parameter Triple Exponential Smoothing model of the Brown type which is appropriate to be used to predict the amount of paddy production in Central Java Province is F28+m=9485520,31-536660,01(m)+(0,5)(-91215,38)(m2), where the number of periods from 1 to 5.
A Review and Analysis of Outcomes from Prevention of Mother-to- Child Transmission of HIV Infant Follow-up Services at a Pediatric Infectious Diseases Unit of a Major Tertiary Hospital in Nigeria: 2007-2020
Authors: UGOCHUKWU EBELECHUKU FRANCESCA , ONUBOGU CHINYERE UKAMAKA , EDOKWE EMEKA STEPHEN , EKWOCHI UCHENNA , OKEKE KENNETH NCHEKWUBE , UMEADI ESTHER NGOZI , ONAH STANLEY KENECHI 
Published: December 2021

Background and Objective: Above 90% of childhood HIV infections result from mother-to child transmission (MTCT). This study examined the MTCT rates of HIV-exposed infants enrolled in the infant follow-up arm of the prevention of mother-to-child transmission (PMTCT) program in a teaching hospital in Southeast Nigeria.
Methods: This was a 14-year review of outcomes of infants enrolled in the infant follow-up arm of the PMTCT program of Nnamdi Azikiwe University Teaching Hospital Nnewi, Nigeria. The majority of subjects were enrolled within 72 hours of birth and were followed up until 18 months of age according to the National Guidelines on HIV prevention and treatment. At enrollment, relevant data were collected prospectively, and each scheduled follow-up visit was recorded both electronically and in physical copy in the client’s folders. Data were analyzed using SPSS version 20. The major outcome variable was final MTCT status.
Results: Out of 3,784 mother-infant dyads studied 3,049 (80.6%) received both maternal and infant Antiretroviral (ARV) prophylaxis while 447 (11.8%) received none. The MTCT rates were 1.4%, 9.3%, 24.1%, and 52.1% for both mother and infant, mother only, infant only, and none received ARV prophylaxis respectively. There was no gender-based difference in outcomes. The MTCT rate was significantly higher among mixed-fed infants (p<0.001) and among those who did not receive any form of ARVs (p<0.001). Among dyads who received no ARVs, breastfed infants significantly had a higher MTCT rate compared to never breastfed infants (57.9% vs. 34.8%; p<0.001). The MTCT rate was comparable among breastfed (2.5%) and never-breastfed (2.1%) dyads who had received ARVs. After logistic regression, maternal (p<0.001, OR: 7.00) and infant (p<0.001, OR: 4.00) ARV prophylaxis for PMTCT remained significantly associated with being HIV-negative.
Conclusion and Global Health Implications: Appropriate use of ARVs and avoidance of mixed feeding in the first six months of life are vital to the success of PMTCT programs in developing countries. PMTCT promotes exclusive breastfeeding and reduces the burden of pediatric HIV infection, thereby enhancing child survival.

Copyright © 2021 Ugochukwu et al. Published by Global Health and Education Projects, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution License CC BY 4.0.
Novel Active Inflow Control Technology for Optimized Flow and Reduced Intervention
Authors: Dikshit Ashutosh , Agnihotri Vivek , Plooy Mike , Kumar Amrendra , Gurbanov Seymur , Erives Valeria , Tripathi Abhinandan 
Published: December 2021

Summary
Integrating a flow control sliding sleeve into a sand screen can provide multiple advantages to the user in controlling the production inflow, but it comes with an increased completion cost as well as an increase in the number of interventions required when it is time to operate those valves. Especially in long horizontal wells, this can become time-consuming and inefficient. A few technologies exist to address this issue, but they either are too complex or require specialized rigging equipment at the wellsite, which is not desirable. As described herein, a unique, fit-for-application modular sliding sleeve sand screen assembly with dissolvable plugs was developed that eliminates the need for washpipe during run-in-hole (RIH) and allows flow control from several screens by means of a single sliding sleeve door (SSD), thereby also optimizing the subsequent intervention operations by reducing the number of SSDs in the well. The design and field installation of these modular screens is presented in this paper. The new modular sand screen consisted of an upper joint, modular middle joint, modular middle joint with an inflow control device (ICD) integrated into an SSD (with optional dissolvable plugs), a lower joint, and novel field-installable flow couplings between them. The design allows for any number of non-ICD/SSD screen joints to be connected to any number of ICD/SSD joints in any order. A computer-aided design was followed to achieve all the operational and mechanical requirements. Computational fluid dynamics (CFD) was used to optimize the flow performance characteristics. Prototypes were manufactured and tested before conducting successful field trials. The design process, development, and field installation results are presented herein.
Dimethyl Ether as a Novel Solvent for Bitumen Recovery: Mechanisms of Improved Mass Transfer and Energy Efficiency
Authors: Yang Min , Chai Maojie , Qi Rundong , Chen Zhangxin , Zhang Linyang , Yu Xinran 
Published: December 2021

Summary
A solvent-based thermal recovery process has the advantages of low capital expenditure, less energy consumption, and less greenhouse gas emission. Dimethyl ether (DME), as a renewable solvent, has been considered as a novel additive in the thermal bitumen recovery process. Being soluble in both water and oil phases, DME has the potential to enhance mass transfer and improve oil production. In this work, a phase behavior model of the DME-bitumen-water system is first developed considering DME partitioning between oil and water. A field-scale numerical simulation model with fine gridblocks is developed to investigate the heat and mass transfer mechanisms between DME and bitumen in the interface of a DME vapor chamber. The numerical model is validated with physical experiment results. The close agreement between measured and simulated production profiles indicates that the mechanisms are adequately captured. Meanwhile, various simulation scenarios are performed to evaluate the production performance and the energy efficiency, which is defined as the energy/oil ratio.
It is found that the oil production rate in DME injection is 15% higher than that in butane injection at the early stage of production. The solvent penetration depth in DME injection is larger than that in butane injection. This is attributed to the enhanced mass transfer between DME and bitumen caused by the high diffusion of DME in the water phase and preferential partitioning of DME into the oil phase. Furthermore, energy consumption in the warm DME injection process is 48% less than that in warm butane injection and 75% less than that in steam-assisted gravity drainage (SAGD). This is because DME injection can be operated at a lower-temperature condition, leading to less energy transferred to heat reservoir rock/fluids and less heat loss to over/underburden. Therefore, DME is proved to be a technically promising and environmentally friendly solvent to enhance bitumen recovery. The DME-based thermal recovery technique exhibits superior advantages in unlocking poor-quality reservoirs, especially in high water saturation reservoirs and thin reservoirs.
Quantification and Degradation of 2,2-Dibromo-3-Nitrilopropionamide (DBNPA) in Bioethanol Fermentation Coproducts
Authors: Simpson John V. , Wiatr Christopher Louis 
Published: December 2021

Abstract
2,2-Dibromo-3-Nitrilopropionamide (DBNPA) has been used as a biocide in industrial water applications due to its instantaneous antimicrobial activity and rapid chemical breakdown. In this study DBNPA is considered as a potential alternative for antibiotics used for bacterial control during corn to ethanol fermentation. A method using LC/MS/MS was developed to accurately quantify DBNPA in water. When this method was applied to quantify DBNPA concentration in a fermentation matrix, DBNPA was found to be unstable and to decay rapidly, preventing validation of the method or quantitation. This method was then used to evaluate the degradation rate of DBNPA in whole stillage, which is the nonvolatile residue produced by removal of ethanol from corn-based fermentation beer by distillation through the relative decrease in measured signal. In addition, a method was developed and validated to quantify bromide, one of the degradation products of DBNPA, in whole stillage using LC/MS/MS. The degradation rate of DBNPA in whole stillage was found to display first order kinetics with a calculated half-life of 85 min. Laboratory analytical chemistry results on DBNPA degradation were confirmed in field trials.
The Evaluation of Energy Consumption in Transportation and Processing of Municipal Waste for Recovery in A Waste-To-Energy Plant A Case Study of Poland
Authors: Nowakowski Piotr , Wala Mariusz 
Published: December 2021

Abstract
Refuse-derived fuel (RDF) can be produced from combustible materials contained in municipal waste. After pre-treatment of waste it is possible shipping RDF a waste-to-energy plant (WtE). This article investigates energy and material flow of waste for different scenarios for production of RDF from bulky waste, separately collected waste, and mixed municipal solid waste (MSW). We compare the proportion of energy consumption in transportation, handling waste, and processing using data from the waste collection company in the South of Poland. The findings show the components of the reverse supply chain consuming the highest value of the energy. A model of material and energy flow has taken into consideration collection of waste and transportation by two categories of waste collection vehicles light commercial vehicles and garbage trucks. The shipping of RDF from pre-treatment facility uses – tipper semi-trailers and walking floor trailers. The findings of the study show production of RDF from municipal solid waste is consuming almost 10% of energy potential in RDF. Less energy is required for the production of RDF from bulky waste 2.2% – 4.8% or separately collected waste 1.7% – 4.1% depending on the efficiency of collection and selected vehicles. The transportation is consuming greatest portion of energy. For mixed municipal solid waste (MSW) it can reach 79%, for separated collection waste 90% and for bulky waste up to 92% of the total energy consumed. Comparing emissions for two categories of the collection vehicles there is no significant difference for the bulky waste collections. For mixed MSW and separately collected waste the emissions are higher for garbage trucks. As a recommendation for practitioners is optimization of routing to achieve higher collection rate for minimized route length. Transportation of RDF to WtE plant the vehicles with higher loading capacity are essential.
Impact of Prerelease Methadone on Mortality Among People with HIV and Opioid Use Disorder After Prison Release: Results from a Randomized and Participant Choice Open-Label Trial in Malaysia
Authors: Bazazi Alexander R. , Culbert Gabriel J. , Wegman Martin P. , Heimer Robert , Kamarulzaman Adeeba , Altice Frederick L. 
Published: December 2021

Abstract
Introduction: Mortality is elevated after prison release and may be higher in people with HIV and opioid use disorder (OUD). Opioid agonist therapy (OAT) with methadone or buprenorphine reduces mortality in people with OUD and may confer benefits to people with OUD and HIV leaving prison. Survival benefits of OAT, however, have not been evaluated prospectively in people with OUD and HIV leaving prison. Methods:This study prospectively evaluated mortality after prison release and whether methadone initiated before release increased survival after release in a sample of men with HIV and OUD (n=291). We linked national death records to data from a controlled trial of prerelease methadone initiation conducted from 2010 to 2014 with men with HIV and OUD imprisoned in Malaysia. Vital statistics were collected through 2015. Allocation to prerelease methadone was by randomization (n=64) and participant choice (n=246). Cox proportional hazards models were used to estimate treatment effects of prerelease methadone on postrelease survival. Results: Overall, 62 deaths occurred over 872.5 person-years (PY) of postrelease follow-up, a crude mortality rate of 71.1 deaths per 1000 PY (95% confidence interval [CI] 54.5–89.4). Most deaths were of infectious etiology. In a modified intention-to-treat analysis, the impact of prerelease methadone on postrelease mortality was consistent with a null effect in unadjusted (hazard ratio [HR] 1.3, 95% CI 0.6–3.1) and covariate-adjusted (HR 1.2, 95% CI 0.5–2.8) models. Predictors of mortality were educational level (HR 1.4, 95% CI 1.0–1.8), pre-incarceration alcohol use (HR 2.0, 95% CI 1.1–3.9), and lower CD4+ T-lymphocyte count (HR 0.8 per 100-cell/mL increase, 95% CI 0.7–1.0). Conclusions: Mortality after prison release in this sample of men with HIV and OUD was extraordinarily high and unaffected by prerelease methadone. Treatment of OUD alone may be insufficient to reduce mortality in settings where inadequately treated HIV is the main cause of death after prison release. Trial registration number: NCT02396979. Retrospectively registered 24/03/2015.
Part Three: Biomarker Changes in Cigarette Smokers Switched to Vuse Solo or Abstinence: A Randomized, Controlled Study
Authors: Kanobe Milly N. , Jones Bobbette A. , Nelson Paul , Brown Buddy G. , Chen Peter , Makena Patrudu , Schmidt Eckhardt , Darnell John , Caraway John W. , Prasad G. L. , Nordskog Brian , Round Elaine K. 
Published: December 2021

Abstract
Biomarkers of exposure (BoE) can help evaluate exposure to combustion-related, tobacco-specific toxicants after smokers switch from cigarettes to potentially less-harmful products like electronic nicotine delivery systems (ENDS). This paper reports data for one (Vuse Solo Original) of three products evaluated in a randomized, controlled confinement study of BoE in smokers switched to ENDS. Subjects smoked their usual brand cigarette ad libitum for two days, then were randomized to one of three ENDS for a 7-day ad libitum use period, or to smoking abstinence. Thirteen BoE were assessed at baseline and Day 5, and percent change in mean values for each BoE was calculated. Biomarkers of potential harm (BoPH) linked to oxidative stress, platelet activation, and inflammation were also assessed. Levels decreased among subjects randomized to Vuse Solo versus Abstinence, respectively, for the following BoE: 42–96% vs. 52–97% (non-nicotine constituents); 51% vs. 55% (blood carboxyhemoglobin); and 29% vs. 96% (nicotine exposure). Significant decreases were observed in three BoPH: leukotriene E4, 11-dehydro-thromboxane B2, and 2,3-dinor thromboxane B2 on Day 7 in the Vuse Solo and Abstinence groups. These findings show that ENDS use results in substantially reduced exposure to toxicants compared to smoking, which may lead to reduced biological effects.
Detection of SARS-CoV-2 in Exhaled Breath from Non-Hospitalized COVID-19-Infected Individuals: A Proof-of-Concept Study
Authors: Leding Cæcilie , Skov Julia , Uhrbrand Katrine , Lisby Jan Gorm , Hansen Katrine Pedersbæk , Benfield Thomas , Duncan Louise Katrine 
Published: December 2021

Abstract
Background: The diagnosis of COVID-19 is based on detection of SARS-CoV-2 in oro-/nasopharyngel swabs, but because of uncomfortness and minor risk for the tested individual during the swab procedure, detection of SARS-CoV-2 has been investigated in other biological matrixes.Methods: In this proof-of-concept study, confirmed SARS-CoV-2-infected individuals performed a daily air sample through five days. Air samples were obtained through a non-invasive electrostatic air sampler. Detection of SARS-CoV-2 RNA were determined with qRT-PCR. The association of positive samples with clinical characteristics was evaluated through mixed-effect models.Results: We obtained 665 air samples from 111 included patients with confirmed SARS-CoV-2 infection. Overall, 52 individuals (46.8%) had at least one positive air sample, and 129 (19.4%) air samples were positive for SARS-CoV-2. Patients with symptoms or a symptom duration ≤ four days had significantly higher odds of having a positive air sample. Cycle threshold values were significantly lower in samples obtained ≤ 4 days from symptom onset. Neither variant of SARS-CoV-2 nor method of air sampling were associated with a positive air sample.Conclusion: We demonstrate that SARS-CoV-2 is detectable in human breath, and suggest further evaluation of air sampling considering the non-invasive, point-of-care method.
GhAIL6, a Member of the AP2 Family Gene, Promotes Somatic Embryogenesis in Cotton.
Authors: Ma Congcong , Li Yilin , Zhang Xiaorui , Ma Dan , Sun Ruibin , Liu Chuanliang 
Published: December 2021

Abstract
Background Somatic embryogenesis (SE) is the process by which plant somatic cells are cultured in vitro without fertilization to regenerate embryos and develop into intact plants, the difficulty of cotton regeneration has severely limited functional gene research and transgenic breeding. The AP2 family is a relatively large family of transcription factor genes that regulate the process of growth and development, but the role of Aintegumenta-Like6 ( AIL6) in cotton SE has not been reported. Methods The 35S::AIL6:GR vector was constructed and transformed into cotton JH713 by Agrobacterium-mediated method, after 3 years of self-breeding, stable genetic T3 generation positive plants were obtained, identified by Southern, and three lines were selected for the following regeneration experiments.Results The results showed that overexpression of GhAIL6 significantly inhibited the proliferation of callus during the first 30 days, and promoted the embryogenic callus production at about 45 days.Couclusion Our results indicated that GhAIL6 was a key regulator of cotton SE, overexpression of GhAIL6 helped to improve the regeneration efficiency of cotton SE
A Decision-support System for Recycling of Residents’ Waste Plastics in China Based on Material Flow Analysis and Life Cycle Assessment
Authors: LIU MANZHI , Wen Jixin , Zhang Linlin , Wu Jixin , Yang Xiaotao , Qin Ying , Liu Yingjie 
Published: December 2021

Abstract
Recycling waste plastics is one of the important ways to save petroleum resources and reduce carbon emissions. However, the current recycling rate of waste plastics is still low. Material flow analysis can help determine the flow of waste plastics, and life cycle assessment (LCA) can be used to quantify environmental impacts. The present study integrates these two methods into the model construction of the residents’ waste plastics recycling decision-support system. This model construction is followed by sensitivity analysis of the relevant parameters affecting the performance of the waste plastics recycling system. Finally, present study forecasts the recycling system’s performance and environmental impacts by setting four optimization scenarios based on sensitivity analysis. The results show that in 2019, A total of 8.39 million tons of high-end applications were recovered, carbon emissions during the recycling process were 34.9 million tons, and dioxin emissions were 316.11 g TEQ, with a total emission reduction of 24.47 million tons of CO2 compared to the original production. In the scenario of comprehensive improvement, in 2035, the recycling volume of high-end applications will rise to 33.96 million tons, the carbon emissions will rise to 64.73 million tons, the dioxin emissions will drop to 165.98 g TEQ, and the carbon emission reduction will rise to 99.06 million tons. This research has a certain guiding role for policy makers to formulate industry norms and related policies for waste plastic recycling.
The Impact of Financial Development on CO2 Emissions of Global Iron and Steel Industry
Authors: Shao Yanmin , Li Junlong , Zhang Xueli 
Published: December 2021

Abstract
As carbon peaking and carbon neutrality have become a global consensus, more and more countries have introduced relevant policies to adapt to their own countries and formulated corresponding time roadmap. The industrial sector, especially the steel sector, which produces high levels of pollution and carbon emissions, is facing significant pressure to transform its operations to reduce CO2 emissions. Previous studies have shown the importance of financial development (FD) in environmental protection, however, the impact of FD on the CO2 emissions of the steel sector is ignored. This paper examines the impact of FD on the CO2 emissions of the iron and steel industry from a global perspective using comprehensive panel data from a total of 30 countries during the period from 1990 to 2018. Empirical results show that an improved level of FD in a given country reduces the CO2 emissions of the iron and steel industry. Our results also show that the effect of FD on reducing the CO2 emissions of the iron and steel industry in developing countries is less than its effect in developed countries. Estimation results also show the existence of the Environmental Kuznets Curve hypothesis in the iron and steel industry. The mechanism analysis indicates that FD promotes the upgrading of the structure of the iron and steel industry and the reduction of the CO2 emissions by means of the three-stage least square method. Finally, we discuss the policy implications of achieving carbon neutrality in the steel sector.