bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Prevalence of Chronic Sinusitis Symptoms among Inflammatory Bowel Disease Patients at Tertiary Hospital in Riyadh
Authors: Alromaih Saud , Abuhaimed Alanoud , Alkhowaiter Saad , Alkethiri Khaled , Alfarhan Omar , Alkhurayji Saad , Alhazmi Naif , Sumaily Ibrahim 
Published: October 2021

Background:
The etiologies of both chronic rhinosinusitis (CRS) and inflammatory bowel disease (IBD) are not well known. Both are inflammatory diseases that are triggered by genetic and environmental factors. Existing literature lacks the evaluation of the overlap between these clinical entities. Herein, we attempt to determine the prevalence of CRS symptoms among the patients with IBD at King Khalid University Hospital.

Methodology:
This text presents a cross-sectional study on patients with confirmed diagnoses based on colonoscopy and histological findings. Patients were evaluated using the chronic sinusitis survey (CSS) and the rhinosinusitis disability index (RSDI). Other variables evaluated in this study include age, gender, chronic illnesses, duration of the IBD, smoking, medications, and family history.

Results:
Eighty-two IBD patients were enrolled in the study, and of these patients, 61 have Crohn's disease (CD) and 21 have ulcerative colitis (UC). There was no statistically significant difference in the presence of sinonasal symptoms between patients with CD and UC: 11.47% and 9.52%, respectively. CSS score was nonsignificantly higher among CD patients: 10.79 compared to 6.15 for UC patients,P= 0.125. In addition, the RSDI score was higher among CD patients: 13.11 compared to 5.14 in UC patients. However, this difference is not significant,P= 0.069.

Conclusion:
The prevalence of CRS symptoms among IBD patients is comparable to the general population. It was nonsignificantly less prevalent in UC patients in comparison to CD patients.
Viability of Ambulatory Major Ear Surgery and Patient Satisfaction
Authors: Alafaleq Mudy , Alafaleq Salma , Alzahrani Musaed 
Published: October 2021

Background:
Ambulatory ear surgery is expanding worldwide due to improvements in surgeries, and this has had a highly positive impact on both hospital and patient satisfaction. However, ambulatory major ear surgery remains controversial in our region due to a lack of research, which motivated us to conduct this study. The purpose of the research is to assess the safety of ambulatory major ear surgery and elaborate on the patient satisfaction rate.

Methods:
To assess complications, the readmission rate, and patient satisfaction with ambulatory major ear surgery, a prospective study of all such surgeries on pediatric and adult patients in a 1-year period in a tertiary hospital was carried out.

Results:
A total of 47 patients underwent ambulatory major ear surgery, and the results indicated an 89.4% discharge rate and 10.6% readmission rate, as well as high patient satisfaction.

Conclusion:
Our study showed a rather low complication rate and high patient satisfaction rate with ambulatory major ear surgery. This should encourage other hospitals in the Kingdom of Saudi Arabia to apply ambulatory ear surgery.
The COVID-19 and Its Impact on Otolaryngology Trainees' Competency and Their Psychological Well-Being
Authors: AlSharhan Salma Saud , Al Bar Mohammed H. , AlSaied Abdulmalik S. , ALEnazi Abdulaziz S. , Aljubran Hussain Jwad , AlKhaldi Saud K. , Alghamdi Amal A. 
Published: October 2021

Background:
As a consequence of the COVID-19 global pandemic, otolaryngology residents are at high risk due to the nature of the specialty and long work hours. Moreover, COVID-19 could have a severe impact on residents from different frontline specialties, particularly otolaryngology. To the best of our knowledge, this is the first nationwide survey providing insights into the otolaryngology residents' prospective of view about the impact of COVID-19 on their training competency development as well as related worries and concerns.

Methods:
A cross-sectional questionnaire-based study was conducted among all otolaryngology training centers of Saudi Arabia to investigate the extent of the impact of COVID-19 on otolaryngology residents and the learning process.

Results:
A total of 152 residents were contacted to participate in the study, and 101 participants were included after successfully completing the questionnaire. The mean age of the participants was 28.12 years (standard deviation = 1.89, max = 36, min = 25). There has been a significant impact on outpatient clinics, elective operations, consultations, and working hours. Further, we evaluated the impact on academic training activities, the frequency of training activities per week, and the psychological impact of the COVID-19 pandemic on otolaryngology residents as well.

Conclusion:
COVID-19 has had a serious impact on residents both physically and mentally; otolaryngology residents have been hit, especially hard by this emergency pandemic period. Trainees suffered from excessive worries regarding clinical training, specifically academic concerns for different training levels. Further studies need to be done here in Saudi Arabia to evaluate this impact in greater detail and to protect the residents.
EPIDEMIOLOGICAL CHARACTERISTICS OF LEPTOSPIROSIS IN VOJVODINA, SERBIA, 2009-2018, FROM THE ASPECT OF ONE HEALTH
Authors: Pustahija Tatjana , Vuković Vladimir , Ristić Mioljub , Medić Snežana , Tomašević Tanja , Rajčević Smiljana , Štrbac Mirjana , Savić Sara , Grgić Živoslav 
Published: October 2021

This study attempts to summarize epidemiological characteristics of human leptospirosis and to determine the seroprevalence of this disease among domestic animals in the Autonomous Province of Vojvodina, for the period 2009-2018. Chronological, demographic and topographic characteristics of human cases were analyzed. Pearson's correlation was used to explore correlations between different meteorological factors and trends in time-series of human cases. Overall 87 human cases of leptospirosis and five subsequent deaths (CFR: 5.75%) were recorded in the ten-year period. The average annual incidence rate was 0.45/100,000 (range: 0.16-1.50/100,000). The disease was more prevalent in males (M/F=16.40:1), with the majority of cases reported in August (N=23; 26.44%), September (N=20; 23.00%) and October (N=15; 17,24%). A statistically significant weak positive correlation was observed between the mean monthly air temperature and the number of human cases of leptospirosis of the same month (r=0.30, p<0.01) and a statistically significant weak positive correlation was found between the number of human cases and the sum of precipitation in the previous month (r=0.27, p<0.01). The average annual seroprevalence among domestic animals in total was 1.13% (range: 0.23% -3.65%). Seropositivity of tested samples of cats, dogs, cattle, donkeys, horses, sheep, pigs and goats was 25%, 9.50%, 8.55%, 6.25%, 1.59%, 0.25%, 0.18%, 0.00, respectively. Human and animal leptospirosis continuously occurs in Vojvodina, which implies the need for continuous and quality monitoring of the epidemiological and epizootiological situation of this disease. Further, more comprehensive parallel studies in humans and animals are needed, as well as additional studies of living conditions of animals on farms with leptospirosis and the studies that will determine the strength of association between climatic/ environmental factors and leptospirosis in Vojvodina.
Key words: Human leptospirosis, animal leptospirosis, zoonosis, epidemiology, seroprevalence, one health.
DETECTION OF BORRELIA SPIROCHETES IN TICKS WITH q16 REAL-TIME PCR
Authors: Zekic Stosic Marina , Tomanović Snežana , Sukara Ratko , Milošević Smiljana , Savic Sara 
Published: October 2021

Lyme disease is a tick-borne disease caused by Borrelia burgdorferi s.l. spirochaetes. It is transmitted by several hard ticks of the genus Ixodes, mainly Ixodes ricinus in Europe. Higher environment temperature caused by climate changes is linked to a higher activity of ticks during most of the year, thus the importance of tick-borne diseases is increasing in the region.
A total of 90 ticks were collected by removing from humans. Every tick collected was identified regarding the species. Total of 79 ticks belonging to the genus Ixodes were tested for the presence of the pathogen strains of Borrelia burgdorferi s.l, Borrelia afzelii, Borrelia garinii and Borrelia burgdoreri sensu stricto by a real-time PCR assay targeting the recA gene. In total, 8 of them tested positive. Representative samples were tested with conventional PCR and results were in accordance.
This study showed that the Genesig q16 Real-Time PCR is an easy diagnostic test for fast detection of Borrelia spirochetes in ticks.
Key words: Lyme disease, tick-borne disease, real-time PCR, Borrelia
Antibiogram of Gram Negative Uropathogens in a Tertiary Care Hospital
Authors: Davane Milind , Mundhe Sanjivani 
Published: October 2021

Background: Globally, urinary tract infection (UTI) is considered a major public health concern and the second most common bacterial infection affecting individuals of different ages worldwide. Urinary tract infections (UTIs) are caused by multiplicity of microorganisms. The chronicity of different bacterial isolates and their propensity to various antibiotics may differ widely, particularly in hospitalized patients, that makes the study of susceptibility pattern mandatory for a proper selection of antibiotics. Objective: To evaluate antimicrobial susceptibility pattern of the Gram negative organisms isolated from urine cultures of hospitalized patients.
Material and Methods: A total of 500 urine samples from hospitalized patients which showed significant bacteriuria were studied. Samples were inoculated on Blood agar and MacConckey agar. Further identification and study of organisms was done by standard Microbiological methods. Antimicrobial Susceptibility pattern was studied by Modified Kirby- Bauer’s disc diffusion method with the panel of 15 drugs as per Clinical Laboratories Standard Institute (CLSI) guidelines. Results: UTIs were found more common in females 290 (58%). Commonest organism found was Escherichia coli 260 (52%) followed by Klebsiella spp. 120 (24%), Pseudomonas spp. 40 (8%), Proteus spp. 38 (7.6%), Citrobacter spp. 25 (5%) and Acinetobacter spp. 17 (3.4%). Majority of the strains were found sensitive to nitrofurantoin followed by amikacin, piperacillin-tazobactam and cotrimoxazole. Commonly prescribed fluroquinolones were found least effective for treatment of UTI. All the strains were found sensitive to imipenem. Extended spectrum beta lactamase (ESBL) was noted in E.coli and in Klebsiella spp. Conclusion: To discourage the indiscriminate use of antibiotics and to prevent further development of bacterial drug resistance, proper knowledge of susceptibility pattern of uropathogens in particular area is very important before prescribing any empirical antibiotic therapy.
Manajemen Anestesi pada Seksio Sesarea dengan Idiopathic Thrombocytopenic Purpura: Serial kasus
Authors: Haryanto Achmad , Hartono Ruddi , Isngadi Isngadi 
Published: October 2021

Trombositopenia merupakan perubahan hemostasis yang umum terjadi pada wanita hamil, namun jarang ditemukan kondisi berat. Idiopathic thrombocytopenic purpura (ITP) merupakan salah satu penyebab trombositopenia pada wanita hamil. ITP ditandai dengan peningkatan penghancuran trombosit oleh antibodi immunoglobulin G (IgG) yang dapat meningkatkan risiko perdarahan pada pasien dan fetus. Kami melaporkan tiga kasus wanita hamil dengan ITP yang akan dilakukan tindakan seksio sesarea. Satu pasien menjalani seksio sesarea emergency dengan trombosit 4000 dan dua pasien menjalani seksio sesarea elektif. Pasien seksio sesarea elektif diberikan transfusi trombosit perioperatif terlebih dahulu. Ketiga pasien menjalani prosedur seksio sesarea dengan teknik anestesi general. Pemantauan perdarahan dilakukan selama sampai dengan setelah operasi. Kondisi postoperatif pasien baik dan dirawat di ruang intensive care unit (ICU).
Case Series: Anesthesia Management in Caesarean Section with Idiopathic Thrombocytopenic Purpura
Abstract
Thrombocytopenia is the most common hemostatic change in pregnancy, but severe thrombocytopenia is rare. One of the causes, idiopathic thrombocytopenic purpura (ITP), is characterized by increased platelet destruction by immunoglobulin G (IgG) antibodies, presenting a high risk of hemorrhage for the patient, but also the fetus, since antibodies may cross the placenta. We report three cases of pregnant women with ITP undergoing cesarean section. One patient underwent emergency cesarean section with a platelet of 4000 and two patients underwent elective cesarean. Patients with elective cesarean section were given the first perioperative platelet transfusion. The cesarean section procedures were performed under general anesthesia. Bleeding monitoring is carried out during up to after surgery.
RELATIONSHIP OF D-DIMERS WITH THE DURATION OF CEREBRAL VENOUS SINUS THROMBOSIS (CVST): A DESCRIPTIVE STUDY IN TERTIARY HEALTH CARE HOSPITAL OF DISTRICT PESHAWAR PAKISTAN.
Authors: Zafar Ayesha , Abid Saima , Ali Fawad , Alam Mehtab , Zafar Syed 
Published: October 2021

Purpose CVST is a serious condition with a recent incidence of 13 million persons per year. (1) It has a highly variable presentation and may manifest itself with no recognizable risk factor, Magnetic resonance venography (MRV) is the investigation of choice for its diagnosis. However, since MRV is not readily available and is costly, this study tried to find the relationship between the levels of D-dimers as marker and duration of CVST. D-dimers are degraded fibrin products which are found to be raised in pulmonary embolism and deep venous thrombosis.
Methods: Total 49 patients (male to female ratio 1:6) mean age 36.37 13years) with MRV proven CVST were included in the study. This descriptive cross-sectional study was conducted from January 2015-April 2017, on 49 confirmed patients of CVST, in Lady Reading Hospital. In patients suspected of CVST, magnetic resonance imaging of the brain with MRV was performed without delay on a 1.5 tesla MR scanner using T1, T2, flair, and diffusion weighted imaging sequences with a two-dimensional time of flight MRV. D-dimers were estimated by a rapid latex agglutination slide test technique using monoclonal antibodies. Data was analyzed using SPSS version 19. Frequencies, mean were calculated for quantitative data while Chi-square test was used for qualitative data. Sensitivity and specificity were calculated.
Result: The duration of symptoms was 3-60 days (mean 22 days). The mean value of D-dimers levels recorded in micrograms were recorded as 1456
Conclusion: D-dimers levels were high in acute and subacute stage of CVST. However, there were cases in our study who despite having acute and subacute stage of CVST had normal D-dimers levels for unknown reasons.
INFLUENCE OF STRATEGIC MANAGEMENT BEST PRACTICES ON PERFORMANCE OF COMMERCIAL BUILDING PROJECTS REGISTERED BY NATIONAL CONSTRUCTION AUTHORITY IN NAIROBI CITY COUNTY, KENYA
Authors: BRIAN JOB MARUBE ONG’ERA , KEPHA OMBUI 
Published: October 2021

Purpose: The purpose of the study was to examine influence of strategic management best practices on performance of commercial building projects registered by national construction authority in Nairobi City County, Kenya

Methodology: A descriptive survey design was adopted by the study and a total of 289 commercial building projects registered by National Construction Authority in Nairobi City County was the target population, as shown in NCA (2020) directory. Using Kothari (2014) sample size formula, the study got 167 commercial building projects. This study used simple random sampling to get the firm. A structured questionnaire was used to collect primary data. The questionnaire was set in likert scale format to capture quantitative data. Data analysis entailed descriptive analysis such as means, frequency and percentages. Data was also analyzed through inferential analysis which entails correlation and regression. Statistical tests were conducted at five percent level of significance and the findings were presented through tables and figures.

Results and conclusion: The coefficient of determination also called the R2 was 0.634. R2 value of 0.634 means that 63.4% of the corresponding variation in performance of commercial building projects registered by National Construction Authority in Kenya can be explained or predicted by (information technology adoption, strategic partnerships, customer experience management, team management) which indicated that the model fitted the study data.The findings of the study indicated that information technology adoption, strategic partnerships, customer experience management and team management have a positive relationship with performance of commercial building projects registered by National Construction Authority in Kenya.

Policy recommendation:the study recommends that companies should embrace strategic management best practices so as to improve performance and further researches should to be carried out in other institutions to find out if the same results can be obtained.
STRATEGI PENGUATAN PRODUK PERUSAHAAN MELALUI BRANDING PADA PT GARSINDO ANUGERAH SEJAHTERA GRESIK
Authors: Hadipurnomo Eereena Anastasia , Utari Woro , Hartati C. Sri 
Published: October 2021

Tujuan penelitian ini adalah untuk mendeskripsikan kondisi daya saing produk garam PT Garsindo Anugerah Sejahtera, untuk menjelaskan branding meningkatkan daya saing produk garam PT Garsindo Anugerah Sejahtera, untuk menjelaskan pilihan strategi branding guna meningkatkan strategi penguatan produk garam PT Garsindo Anugerah Sejahtera.
Jenis penelitian ini adalah deskriptif dengan pendekatan kualitatif. Penelitian ini dilakukan di PT Garsindo Anugerah Sejahtera, Gresik, Jawa Timur. Sebanyak lima informan menjadi sumber pengumpulan data dalam penelitian ini. Penelitian dilakukan secara semi-terstruktur dengan wawancara mendalam (in-depth interview).
Hasil penelitian menunjukkan bahwa kondisi daya saing garam produk PT Garsindo dalam kondisi yang baik. Branding terbukti mampu memperkuat produk perusahaan yang terungkap dari peningkatan daya saing produk-produk yang dijual oleh perusahaan di pasar domestik, bahkan sebagian sudah mulai bisa diekspor ke Jepang. Branding yang kuat mampu memperluas pangsa pasar dan memudahkan para distributor untuk memasarkan produk-produk yang diciptakan oleh perusahaan. Dari sisi inovasi produk juga menunjukkan keterkaitan antara branding dan inovasi terhadap peningkatkan penjualan garam.
KEHALALAN VAKSIN BERUNSUR BABI
Authors: Chodir Fatkul 
Published: October 2021

Tulisan ini mengkaji tentang status hukum vaksin covid-19 Astrazeneka yang terindikasi memanfaatkan media tripsin babi yang menuai kontroversi di tengah masyarakat. Polemik semakin mengemuka setelah keluar fatwa yang berbeda antara MUI Pusat yang mengharamkan dengan MUI Jawa Timur yang menghalalkan vaksin Astrazeneka. Makalah ini berpendapat bahwa dengan menerapkan teori istihalah, setelah melalui proses produksi yang panjang telah terjadi perubahan baik secara substansi maupun bentuk sehingga nomenklatur juga berubah, maka vaksin astrazeneka yang memanfaatkan tripsin babi dihukumi suci dan halal. Hukum halal tersebut didasarkan atas argumentasi bahwa illat hukum yang menyebabkan keharaman telah hilang.
МӘЛІМЕТТЕР БАЗАСЫНДАҒЫ АҚПАРАТТЫҚ ЖҮЙЕЛЕРДЕ ІЗДЕУ ЖЕДЕЛДЕТУ МҮМКІНДІКТЕРІ
Authors: Басшықызы Динара 
Published: October 2021

Кез келген мәліметтер базасы әртүрлі сұратымдардан тұрады. Сұратымдардың қызметі пайдаланушыға мәліметтер базасынан белгілі бір ақпараттарды көрсету болып табылады, яғни олардың негізгі қызметі іздеу болып табылады. Сондықтан неғұрлым кесте көп болса, соғұрлым сұратымдарда көп болады. Ауқымды мәліметтер базасында сұратымдар саны көп болғандықтан, немесе олардың логикалық тұрғыда дұрыс құрылмағандықтан сұратымдар баяу жұмыс істейді, ал ондай сұратымдар бүкіл мәліметтер базасын баяу жұмыс істеуіне әкеліп соқтырады. Сондықтан осындай жағдайды алдын-алу үшін сұратымдардың жылдамдығын жие-жие өлшеу қажет. Қазіргі заманғы компьютерлік өнеркәсіпте SQL тілі ең маңызды тенденция болып отыр. Соңғы жылдары SQL тілі мәліметтер базасының жалғыз тілі болды. Бүгінгі таңда SQL дербес компьютерлерде жұмыс істейтін МБ-ның жүзден астамын қолдайды. SQL тілі мәліметтер базасын басқару жүйелерінің архитектурасындағы маңызды буын болып табылады. SQL (Structured Query Language) – бұл құрылымдық сұраныстар тілінің қысқартылған атауы. Ол реляциялық мәліметтер базасында мәліметтерді құру және өңдеу құралдарын береді. Компьютерлік технологиялардан ерекшелігінен тәуелсіздігі және SQL-ді реляциялық мәліметтер базасының технологиясы облысындағы өндіріс жетекшілерімен қолдауы оны деректер базасының стандартты тіліне айландырды. SQL тілі мәліметтер базасының реляциялық типімен ғана жұмыс істейді. Төменде SQL жұмысының сұлбасы бейнеленген. Есептегіш жүйеде маңызды ақпарат сақталған мәліметтер базасы болады. Егер есептегіш жүйе кәсіпорынның кадрлар бөліміне қатысты болса, онда деректер базасында кәсіпорында қызмет ететін адамдар жайлы ақпарат (аты-жөні, туған жылы, телефоны, қызметі және т.б.) сақталуы мүмкін. Мәліметтерді сұрау және нәтиже алу процесі мәліметтер базасында сұраныстар деп аталады, яғни сұраныстардың құрылымдық тілі.
OUTCOME OF CATARACT SURGERY IN CHILDREN
Authors: Haroon Rashid  , Faizur Rahman  , Sayed Ashfaq Ali Shah  , Muhammad Ali Jan  
Published: October 2021

Objectives: To evaluate the management and visual outcome of cataract surgery in children.
Study design: Descriptive.
Material and Methods: This study included one hundred pediatric patients having cataracts over a periodof two year, from Is' January 2005 to 31 st December 2006, at the Department of Ophthalmology, SaiduTeaching Hospital, Saidu Sharif, Swat.
Results: Age range was fourteen years and below. Sixty five (65%) patients were males and thirty five (35%) females. Sixty three (63%) patients had congenital or developmental cataracts and thirty seven (37%) had traumatic cataracts. Extracapsular cataract extraction (aspiration) was performed on 150 eyes. Postoperative visual acuity was recordable in 112 eyes. Acorrected visual acuity of 6/18 or better was obtained in50 (44.64%) eyes. Forty one (36.6%) eyes obtained visual acuity of 6/24 to 6/60, while in 21 (18.75%) eyesthe visual acuity remained below 6/60. The most common postoperative complication was development ofthick posterior capsule, which occurred in 51 (34%) eyes and vitreous loss in 10 (6.6%) eyes. Pupil blockglaucoma developed in 4 (2.66%) eyes. No case developed endophthalmitis. Posterior chamber IOL wasimplanted in 9 (6%) eyes.
Conclusions: Management of cataracts in children is still a problem and delayed presentation leads to poorvisual outcome. The public should be educated to seek early treatment for childhood cataracts. Paramedicsand doctors should be made aware of the problem and its management. Management of unilateral cataractsis still a difficult problem. Therefore search should continue for better surgical approach and better methodsof correction of aphakia so as to achieve better visual outcome.
Key words: Childhood Cataracts, Congenital Cataracts and Traumatic Cataracts.