bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of cognitive behavioral therapy on depression, anxiety, sleep and quality of life for patients with heart failure and coronary heart disease. a systematic review of clinical trials 2010 – 2020
Authors: Pizga Aspasia , Kordoutis Panagiotis , Tsikrika Stamatoula , Vasileiadis Ioannis , Nanas Serafeim , Karatzanos Eleftherios 
Published: July 2021

Background: There is a growning evidence that CBT (Cognitive Behavioral Therapy) improves mental health of patients with chronic illnesses but its effectiveness is not well established in patients with heart diseases. The present systematic review was conducted to evaluate the effects of CBT in heart failure (HF) and coronary heart disease (CHD) patients.Methods: Pubmed, Cohraine and Google Scholar were searched for studies with randomized controlled trials. Studies were required to assess the effectiveness of CBT in depression, anxiety, sleep and quality of life of patients suffering from heart failure and coronary heart disease. SStudies identified were independently screened by two reviewers and critically appraised using the PedroScale.Results: Sixteen randomized controlled trials were included in the review. The majority of the studies indicated that CBT therapy was effective treatment for reducing depression and anxiety and can also be beneficial for sleeping disorders and improve quality of life of patients with heart failure and coronary heart disease. Althought face to face CBT therapy seems to be clinicaly effective, internet-based CBT therapy was not superior to a guided web-based discussion forum.Conclusions: CBT can improve psychological health and quality of life of cardiac patients and further enhance benefits of rehabilitation programs. Findings suggest that face-to-face CBT is superior to usual care and it can be incorporated in cardiac rehabilitations programs. Future studies are needed to identify the effectiveness of internet-based CBT on cardiac patients and address the factors that will increase treatment adherence.
Ο αποτελεσματικός διευθυντής στο σύγχρονο σχολείο. Αντιλήψεις εκπαιδευτικών φυσικής αγωγής και διευθυντών
Authors: Δεληγιαννίδου Τζένη Στέφανος , Λάιος Αθανάσιος , Σταφυλά Αμαλία 
Published: July 2021

H σχολική ηγεσία έχει αναγνωριστεί παγκοσμίως, ως βασικό στοιχείο της αποτελεσματικότητας του εκπαιδευτικού οργανισμού. Οι διευθυντές/τριες των σχολείων κατέχουν κεντρικό ρόλο, ενώ το στυλ, η συμπεριφορά και οι πρακτικές τους επιδρούν στα μαθητικά αποτελέσματα και σε παράγοντες που συνδέονται με το εκπαιδευτικό προσωπικό. Σκοπός της παρούσας έρευνας ήταν: α) η διερεύνηση της σημαντικότητας των παραγόντων που εκφράζουν ορισμένες από τις κύριες ηγετικές λειτουργίες, με την αξιοποίηση ως δεικτών αποτελεσματικότητας των αντιλήψεων των εκπαιδευτικών Φυσικής Αγωγής (ΕΦΑ) και των ίδιων των διευθυντών/τριών, β) η διερεύνηση των στατιστικά σημαντικών διαφορών ανάμεσα στις αντιλήψεις διευθυντών/τριων και ΕΦΑ και γ) η διερεύνηση των στατιστικά σημαντικών διαφορών ανάμεσα στις αντιλήψεις διευθυντών/τριων και ΕΦΑ σε σχέση με το φύλο τους. Το δείγμα της έρευνας αποτέλεσαν τετρακόσιοι δέκα πέντε (415) εκπαιδευτικοί (192 διευθυντές/τριες και 223 ΕΦΑ) που υπηρετούσαν κατά το σχολικό έτος 2017-2018 στις σχολικές μονάδες της Πρωτοβάθμιας και της Δευτεροβάθμιας Εκπαίδευσης των νομών Πιερίας και Ημαθίας. Για τη συλλογή των δεδομένων χρησιμοποιήθηκε το ερωτηματολόγιο της έρευνας των Pashiardis και Orphanou (1999). Η ανάλυση των δεδομένων έγινε με το στατιστικό πακέτο SPSS v.21 για τις κοινωνικές επιστήμες. Για τη διερεύνηση της εγκυρότητας του ερωτηματολογίου εφαρμόστηκε το μοντέλο της παραγοντικής ανάλυσης με τη μέθοδο τω κυρίων συνιστωσών, ενώ η εσωτερική συνέπεια των παραγόντων ελέγθηκε με τον συντελεστή αξιποπιστίας Cronbach’s alpha. Εφαρμόστηκαν στατιστικές αναλύσεις χρησιμοποιώντας κυρίως την περιγραφική στατιστική όπως μέσοι, διάμεσοι, τυπικές αποκλίσεις. Πραγματοποιήθηκε στατιστικός έλεγχος για τη διαφορά των μέσων τιμών των δυο ανεξάρτητων δειγμάτων (independent Samples t-test) προκειμένου να διερευνηθούν οι στατιστικά σημαντικές διαφορές ανάμεσα στις αντιλήψεις των ΕΦΑ και των διευθυντών/τριων. Το ίδιο τεστ χρησιμοποιήθηκε για τη διερεύνηση της επίδρασης της μεταβλητής φύλο (άνδρας, γυναίκα), στις αντιλήψεις ΕΦΑ και διευθυντών/τριων. Από τα αποτελέσματα βρέθηκε ότι τόσο οι ΕΦΑ όσο και οι διευθυντές/τριες, θεώρησαν σημαντικούς τους παράγοντες καθώς τους αξιολόγησαν με τιμές πάνω από τον μέσο όρο. Βρέθηκαν στατιστικά σημαντικές διαφορές στον παράγοντα «επίλυση προβλημάτων και λήψη απόφασης» με τους διευθυντές να τον θεωρούν πιο σημαντικό από τους ΕΦΑ και στον παράγοντα «σχολικά προγράμματα» που θεωρήθηκε πιο σημαντικός από τους EΦΑ. Τέλος δε βρέθηκαν στατιστικά σημαντικές διαφορές ως προς την ανεξάρτητη μεταβλητή φύλο και στους τρεις υπό διερεύνηση παράγοντες τόσο στις αντιλήψεις των ΕΦΑ, όσο και στις αντιλήψεις των διευθυντών/τριων.
Analysing students’ environmental awareness profile using strategic environmental assessment
Authors: Khoiri Ahmad , Sunarno Widha , Sajidan Sajidan , Sukarmin Sukarmin 
Published: July 2021

Background: Environmental awareness (EA) is a part of character education ignored by most students. This indifference tends to affect other students’ by not only in protecting and preserving the current environment but also in preventing and repairing the damage that occurs in the environment. This research analyses students' EA profile, based on the findings of LISREL 8.8 Confirmatory Factor Analysis. Methods: Research subjects included 131 students from Senior High School State 1 Selomerto Wonosobo, Central Java Province, Indonesia. Based on the Slovin formula, the number of samples is representative of the total population (N: 185; error tolerance: 0.05). Data were collected through non-test questionnaires and observation of Strategic Environmental Awareness (SEA). Quantitative descriptive data analysis on EA indicators (Care, Curiosity, Critical, Dependability, Responsibility, and Local Wisdom). Results: The EA profile of high school students was categorised sufficiently. This revealed the following results: a) the SEA instrument is effective in identifying students’ awareness about current environmental issues and meets model fit criteria (P-value 0.25>0.05; RMSEA 0.095; NFI 0.67); b) the SEA instrument is valid and reliable in accurately determining students’ EA profile; c) although the Responsibility profile was significant (t >1.96), other variables did not meet this significance criteria (EA 1a: ‘Care towards environmental damage’ under the Care profile; EA 3b: ‘Contributing towards preserving the environment’ under the Critical profile; and EA 6b: ‘Aware of local potentials’ under the Local Wisdom profile); d) evaluation of the expected changes in SEA is modified through an ethnoscience approach and the socioscientific issues strategy. Conclusions: Students’ lack of awareness of the environment and understanding of their regional potential fails to contribute towards creating a sustainable environment. Profile analysis in exploring attitudes, values, and ethics towards the environment are important, as it helps recognize students’ behaviour.
Screening for antifolate and artemisinin resistance in Plasmodium falciparum clinical isolates from three hospitals of Eritrea
Authors: Mukhongo Harriet Natabona , Kinyua Johnson Kang'ethe , Weldemichael Yishak Gebrekidan , Kasili Remmy Wekesa 
Published: July 2021

Background: Antimalarial drug resistance is a major challenge hampering malaria control and elimination. Plasmodium falciparum, the leading causative parasite species, has developed resistance to basically all antimalarials. Continued surveillance of drug resistance using genetic markers provides important molecular data for treatment policies. This study sought to verify the genetic mechanism of resistance to sulfadoxine-pyrimethamine and assess the occurrence of point mutations associated with artemisinin resistance in P. falciparum clinical isolates from Eritrea. Methods: Nineteen dried blood spot samples were collected from patients visiting Adi Quala, Keren and Gash Barka Hospitals, Eritrea. The patients were followed up after receiving treatment with first line artesunate-amodiaquine. Nested polymerase chain reaction and Sanger sequencing techniques were employed to genotype point mutations in the P. falciparum bifunctional dihydrofolate reductase-thymidylate synthase (Pfdhfr, PF3D7_0417200), dihydropteorate synthase (Pfdhps, PF3D7_0810800) and kelch 13 (PfK13, PF3D7_1343700) genes. Results: Eight of nineteen (42%) of the dried blood spot samples were successful for PCR-amplification. Data analyses of the PCR-positive isolates revealed the following point mutations: Pfdhfr N51I in four isolates, C59R in one isolate, S108N in four isolates, a rare non-synonymous substitution V45A in four isolates and Pfdhps K540E in four isolates. No PfK13 point mutations were reported. Conclusions: Pfdhfr C59R and Pfdhps K540E point mutations are reliable markers for the sulfadoxine-pyrimethamine quintuple mutant haplotype combination. These findings highlight first reports in Eritrea, which verify the underlying genetic mechanism of antifolate resistance. Continuous monitoring of the PfK13 marker is recommended.
Correlation between maternal variables and the onset and severity of preeclampsia
Authors: Amidu Nafiu , Banyeh Moses , Adusu Stephen Justice 
Published: July 2021

Background: The study sought to determine the correlation between the onset and severity of preeclampsia (PE) and maternal sociodemographic variables: age, parity and body mass index (BMI); medical history: systolic blood pressure (SBP), diastolic blood pressure (DBP), and proteinuria; fasting lipids: total cholesterol (TCHOL), high-density lipoprotein (HDL), low-density lipoprotein (LDL) and triglycerides (TRIG); liver enzymes: aspartate transaminase (AST), alanine transaminase (ALT) and gamma-glutamyl transferase (GGT), and other variables: serum neutrophil gelatinase associated lipocalin (sNGAL), endothelin-1 (ET-1) and creatinine (CRT). Methods: This was a case–control study from January–June 2018. The study involved 270 pregnant women aged 18–37 years. Half of the study population (n=135) had PE and were categorized into either early-onset PE (EOPE) or late-onset PE (LOPE) and whether the PE was characterized by severe features (PS) or without severe features (PNS). The cases (PE) were matched by maternal and gestational age to 135 women with normotensive and uncomplicated pregnancies. A single venous blood sample was collected after an overnight fast and analysed using ELISA or routine biochemistry technique. Results: Maternal blood lipids (except HDL), liver enzymes (except GGT), CRT, sNGAL, ET-1, proteinuria, and BMI were positively correlated while HDL was negatively correlated with the onset and severity of PE (P<0.050). Conclusion: There are significant correlations between maternal variables and the onset and severity of PE. These findings are useful for the early detection and management of PE, especially in resource-limited settings.
Expectations about check-up examinations among Swiss residents: A nationwide population-based cross-sectional survey
Authors: Diaz Hernandez Laura , Giezendanner Stéphanie , Fischer Roland , Zeller Andreas 
Published: July 2021

Introduction
General health check-up examinations in asymptomatic adults have not been shown to be beneficial. Instead, opportunistic prevention during regular primary care consultations is most cost-effective and recommended. The study aimed to elucidate the expectations about check-ups of the general Swiss population.

Methods
A nationwide cross-sectional telephone survey was conducted in a representative sample of the population, stratified by sex, age, and language in November 2019.

Results
Data of 1077 respondents were analysed. Mean age was 45 years (range 18 to 89), and 51% were female. Overall, 40% of respondents expected to have check-up examinations (yearly: 41.6%), and 42% expected opportunistic prevention. Most expected check-up interventions were sex-specific such as mammography (89% of women), Pap smear test (89% of women), and blood test of prostate-specific antigen (81% of men). The least favoured ones related to counselling (tobacco: 27%; alcohol abuse: 29%). Most significant predictors of positive check-up expectations were being male (OR = 1.45, CI: 1.02–2.05 P = 0.04)), age between 45 and 59 years old (OR = 2.03, CI: 1.27–3.23, P = 0.003 vs. 18 to 29 years), having a degree from professional (OR = 1.73, 95% CIs: 1.11–2.69, P 0.015) or, middle school (OR = 1.99, 95% CIs:1.04–3.78, P = 0.037) or university (OR = 1.66, 95% CIs: 1.06–2.61, P< 0.001, vs. secondary school) and the more importance attributed to regularly checking one’s health (OR = 2.12, 95% CIs: 1.70–2.36, P < 0.001)

Conclusions
Almost half of the population expected to have mostly yearly check-up examinations in addition to regular care, which is in contradiction to recommendations. This behaviour impacts the rational use of health care resources and must be considered by physicians and given the active role of patients in the health care system.
Implantación de semi-presencialidad en una asignatura optativa de la licenciatura en Ciencias y Técnicas Estadísticas
Authors: Cobo Erick , González José A. 
Published: July 2021

Introducción. Los estudiantes de Aplicaciones de la Estadística en las Ciencias de la Salud llegan con buen nivel en aspectos teóricos, formales e informáticos, y nos proponemos desarrollar sus habilidades de trabajo en equipo y de comunicación oral y escrita, así como sus capacidades cognitivas de análisis, síntesis y evaluación en el área de la Bioestadística. Contenido. Se exponen: (a) la adaptación del programa a un esquema que sustituye las cuatro horas semanales presenciales a un promedio de dos horas quincenales más una serie de actividades complementarias no presenciales; y (b) las dificultades, los resultados, las opiniones emitidas por los estudiantes y las conclusiones de la experiencia.Método. El método docente se ha basado en la realización de las siguientes actividades: 1) tres ejercicios de aprendizaje cooperativo sobre tres guías internacionales de presentación de resultados biomédicos; 2) defensa pública en grupo de un tema; 3) ejercicios numéricos individualizados; 4) prácticas en grupo; 5) tres evaluaciones individuales; y 6) participación en foros de discusión.Conclusiones. La asignatura ha sido seguida con éxito por 21 de los 22 alumnos matriculados, con buena adaptación a la propuesta. Se ha constatado que es posible organizar una asignatura acorde con las especificaciones del espacio europeo de educación superior.
Autoimmune Gastrointestinal Dysmotility in a Patient With HIV Treated With Methylprednisolone and Pyridostigmine
Authors: Gromisch Christopher M. , Machado Mariana A. , Satyam Venkata , Nunes David 
Published: July 2021

ABSTRACT
Primary autoimmune gastrointestinal dysmotility is a limited form of autoimmune dysautonomia, driven by antiganglionic autoantibodies (AGAs) against enteric neurons. AGAs are observed in other autoimmune diseases, such as Guillain-Barré syndrome, before the development onset of gastrointestinal symptoms. Here, we report a case of a 57-year-old woman with human immunodeficiency virus, who previously developed Guillain-Barré syndrome, presenting with 6 months of intestinal dysmotility. Diagnosis was made by detecting AGAs to ganglionic acetylcholine receptor, alpha-3 subunit, radiographic evidence of duodenal dysmotility, and exclusion of other causes. The patient received high-dose methylprednisolone with low-dose pyridostigmine, which led to significant improvement of symptoms.
Active Protection of Magnesium Alloy AZ91D Using Corrosion Inhibitor Encapsulated Halloysite Nanoclay-Based Smart Sol-Gel Coatings
Authors: Adsul Swapnil H. , Sonawane Shirish H. , Subasri R. 
Published: July 2021

Abstract
Magnesium alloys are preferred extensively in automobile and aerospace industries, because of their very low density and high-specific strength. However, magnesium alloys are unstable in highly corrosive environments because of their extremely low standard electrode potential (−2.37 V). One of the most promising approaches to overcome this limitation is the use of eco-friendly and versatile sol-gel coatings. In the present work, corrosion-inhibition ability of various corrosion inhibitors, such as Ce3+-Zr4+, 8-hydroxyquinoline and 2-mercaptobenzothaizole, was evaluated on magnesium alloy AZ91D. For this purpose, inhibitors were loaded in as-received halloysite nanotubes (HNTs), which were then end-stoppered using polymeric microcapsules and dispersed in a hybrid silane matrix. The surface morphology of raw and inhibitor-loaded HNTs was examined with transmission electron microscopy analysis, whereas Brunauer-Emmett-Teller and scanning electron microscopy/energy-dispersive X-ray spectroscopy analyses were carried out to verify the encapsulation of inhibitors. The coatings were developed on coupons of AZ91D by the dip-coating technique, which were then thermally cured for 1 h at 130°C. The anticorrosion ability of inhibitor-encapsulated, HNT-based sol-gel coatings on AZ91D was evaluated using electrochemical impedance spectroscopy and potentiodynamic polarization for different durations of exposure to sodium chloride solution of 0.6 M concentration. Salt spray analysis was also carried out according to ASTM B117, Standard Practice for Operating Salt Spray (Fog) Apparatus, to examine the anticorrosion ability of coatings for a prolonged duration of exposure, 168 h. Electrochemical measurements and salt spray analyses have revealed that Ce3+-Zr4+-loaded HNT-based coatings were found to give better anticorrosion properties during prolonged durations of exposure to extremely corrosive environments, such as a 0.6 M sodium chloride solution.
Oral Health Among Children and Youth With Special Health Care Needs
Authors: Lebrun-Harris Lydie A. , Canto María Teresa , Vodicka Pamella , Mann Marie Y. , Kinsman Sara B. 
Published: July 2021

OBJECTIVES
We sought to estimate the prevalence of oral health problems and receipt of preventive oral health (POH) services among children and youth with special health care needs (CYSHCN) and investigate associations with child- and family-level characteristics.

METHODS
We used pooled data from the 2016–2018 National Survey of Children’s Health. The analytic sample was limited to children 1 to 17 years old, including 23 099 CYSHCN and 75 612 children without special health care needs (non-CYSHCN). Parent- and caregiver-reported measures of oral health problems were fair or poor teeth condition, decayed teeth and cavities, toothaches, and bleeding gums. POH services were preventive dental visits, cleanings, tooth brushing and oral health care instructions, fluoride, and sealants. Bivariate and multivariable logistic regression analyses were conducted.

RESULTS
A higher proportion of CYSHCN than non-CYSHCN received a preventive dental visit in the past year (84% vs 78%, P &lt; .0001). Similar patterns were found for the specific preventive services examined. However, CYSHCN had higher rates of oral health problems compared with non-CYSHCN. For example, decayed teeth and cavities were reported in 16% of CYSHCN versus 11% in non-CYSHCN (P &lt; .0001). In adjusted analyses, several factors were significantly associated with decreased prevalence of receipt of POH services among CYSHCN, including younger or older age, lower household education, non-English language, lack of health insurance, lack of a medical home, and worse condition of teeth.

CONCLUSIONS
CYSHCN have higher rates of POH service use yet worse oral health status than non-CYSHCN. Ensuring appropriate use of POH services among CYSHCN is critical to the reduction of oral health problems.
The shear resistance of a member without shear reinforcement according to Eurocode 2; the error of the calculated value and the mechanical explanation of the problem
Authors: Bogdándy Béla 
Published: July 2021

AbstractIn this paper the shear resistance of a member without shear reinforcement according to Eurocode 2 is investigated. This expression, as most expressions of design codes typically used to estimate the nominal shear resistance, has been created based on experimental investigations. It will be verified that in case of non-prestressed reinforced concrete member without stirrups, the shear resistance is carried by the shear resistance of the compressive zone; and the shear resistance given by the empirical expression of Eurocode 2 is actually the shear resistance of the compressive zone.Knowing the mechanical background of the empirical expressions of Eurocode 2, the limits of its applicability can be shown, thus its error can be predicted. Using the reports of experimental investigations, it is easy to find cases to prove the correctness of the error-prediction. In this paper simple modifications will be suggested to Eurocode 2 shear design procedures, by which a more consistent level of safety can be ensured.
Capítulo 6
Authors: Ramírez Camilo Andrés 
Published: July 2021

El presente documento muestra comofuela planeación y desarrollo pedagógico para la actualización y rediseño del libro interactivo para el aprendizaje activo de las matemáticas. Se parte de una problemática tecnológica, debido a que el libro prexistente está elaborado en el lenguaje Wolfram Mathematica, que presenta dificultades de acceso por parte de los estudiantes. Inicialmente el proyecto era llevar el libro a un lenguaje HTML para que los estudiantes pudiesen acceder, sin embargo, terminó volviéndose un rediseño, donde se implementan elementos de storytelling educativo y avatares de interacción.
Esta es una experiencia que se viene trabajando desde el año 2014, con el objetivo que los estudiantes de la Institución se acerquen a la modelización matemática y al pensamiento matemático, con situaciones del mundo real que se pueden modelar matemáticamente, permitiendo dar sentido a los conceptos y herramientas matemáticas en el mundo que los rodea.
Aspectos generales y definiciones
Authors: Zabala-Leal Tatiana Dulima 
Published: July 2021

Desde la fundación de las primeras organizaciones políticas o Estados, ha sido indiscutible el esfuerzo de estos al dedicar gran parte de su actividad de vigilancia y control a la creación de entes encargados de proteger el patrimonio público y privado, en aras de salvaguardar los derechos económicos y las libertades individuales y sociales de su pueblo y población. De allí que los ordenamientos jurídicos superiores han definido como un deber del Estado el garantizar la convivencia pacífica, equitativa y justa, por lo que la comisión de delitos afecta directamente esta función debilitando la estabilidad económica y la seguridad nacional.