bluuebunny/crossref_metadata_2025_split huggingface dataset:
The prevalence of multiple organ dysfunction syndrome and its relationship with clinical variables in intensive care unit patients in Iran, 2022
Authors: Karami Arman , Abdi Alireza , Raygani Ali Akbar Vaisi , Salari Nader , Mohammadi Mohammad Mehdi 
Published: January 2025

Abstract
Background
Hospitalization in intensive care units (ICUs) often leads to complications. One such complication is multi-organ dysfunction syndrome (MODS). This study aimed to determine the prevalence of MODS and its relationship with clinical variables in ICU patients in Iran, 2022.

Methods
This cross-sectional, descriptive-analytical study included 194 ICU patients from Kermanshah hospitals, selected between 30 April and 1 September 2022. Data collection tools included patient demographic forms, Marshall et al.’s MODS calculation formula (1995), shock index, mNUTRIC, SOFA, APACHE II, and free water deficit. Data were analyzed using the SPSS-25 software.

Results
The study found that 32% were aged 41–60, and 69.6% were male. The average MODS score was 6.87 ± 1.59 (ranging from 0 to 24), with a prevalence of 56.2%. MODS was significantly related to clinical variables such as the number of days in the hospital, days in ICU, number of involved organs, Glasgow Coma Scale (GCS), partial pressure of oxygen (PaO2), shock index, APACHE II score, SOFA score, mNUTRIC score, and free water deficit (P < 0.05).

Conclusion
MODS is highly prevalent among ICU patients. Key clinical factors associated with MODS include the duration of hospitalization, ICU stay, mechanical ventilation, number of involved organs, GCS, PaO2, shock index, APACHE II, SOFA, mNUTRIC, and free water deficit. Attention to these factors in clinical planning and management could be beneficial in addressing MODS in ICU patients.
Enabling analytical precision in microplastic analysis: innovative solutions for precise method validation, evaluation and quality control
Authors: Badzoka Jovan , Kappacher Christoph , Lauß Jakob , Obwaller Lisa , Pavun Anna , Huck Christian W. 
Published: January 2025

AbstractThe growing concern over microplastic (MP) pollution has catalyzed extensive research efforts to comprehensively understand its environmental distribution and impact. Despite the growing number of studies documenting MP presence, the development of a standardized analytical protocol, particularly focusing on precise analytical method validation, remains a challenge. This gap arises from the complex nature of sample matrices and the diverse combinations of sample pretreatment and detection methodologies employed. Consequently, inconsistencies in detected quantities, attributed to overlooked recovery and blank measurements, persist, undermining data reliability and comparability. In this context, this study proposes an innovative solution to enhance the analytical precision for validation and evaluation of MP analysis. Leveraging Fourier Transform Infrared (FT-IR) and Quantum-cascade laser (QCL) imaging, we introduce a method that utilizes potassium bromide (KBr) pellets embedded with microplastics (MPs), facilitating exact particle number determination for method validation and quality control (QC) using FT-IR imaging of formed potassium bromide (KBr) pellets. KBr exhibits optimal properties as a matrix for MP-immobilization due to its excellent water solubility and infrared transparency. Through detailed validation, encompassing recovery, precision, and accuracy parameters, our approach represents a proof of concept that enables robust and reliable MP validation and quality control, addressing critical gaps in current methodologies. Achieved recovery rates for different polymer types and shapes, including LDPE and PVC fragments, as well as, spherical PS beads were all above the 95% mark, demonstrating high accuracy. This method serves to monitor and mitigate potential losses during sample preparation, ensuring greater accuracy and precision in microplastic analysis. By incorporating a custom synthesized polymer with a thione functionality as an internal standard alongside conventional MP polymers, we demonstrate the ability of this approach for comprehensive method validation, evaluation and quality control on a particle-based approach.
Current Evidence for the Use of Jugular Vein Compression Collars in Sport: A Systematic Review
Authors: Delgadillo Blake E. , Montz Frederic , Ward Byron , Herson Andrew B. , Toldi James P. 
Published: January 2025

Abstract
Sport-related concussions are a common type of brain injury, and the best treatment is prevention. Recently, external jugular vein compression collars have been worn by National Football League players, but the current evidence is limited. To the best of the authors' knowledge, this is the first comprehensive, up-to-date systematic review addressing the use of jugular vein compression collars for decreasing concussion incidence in high-impact sports and activities. Overall, when compared to control, the results indicated that jugular vein compression collars resulted in significantly reduced white matter alteration, improved short-term neurocognitive outcomes, increased internal jugular vein cross-sectional area, decreased internal carotid artery cross-sectional area, and moderating effects on peak pulse pressure. There was no significant difference in concussion incidence rate between groups. While promising, these findings warrant future research to assess jugular vein compression collar's role in concussion prevention, brain injury, and long-term neurocognitive outcomes. The authors are hopeful for the role jugular vein compression collars will play in the future.
Ανάπτυξη Σχέσεων Εμπιστοσύνης στις Σχολικές Μονάδες - Πλεονεκτήματα και Προοπτικές, με έμφαση σε περιόδους αβεβαιότητας..
Authors: Keravnos Nicos 
Published: January 2025

Σχολικοί ηγέτες και εκπαιδευτικοί, συνεχώς, χρειάζεται να αναθεωρούν και να προσαρμόζουν τον τρόπο εργασίας τους για να ανταπεξέλθουν με επιτυχία στις προκλήσεις που επιβάλλονται από το εξωτερικό περιβάλλον. Η καθιέρωση και η ενδυνάμωση σχέσεων εμπιστοσύνης μεταξύ του σχολικού ηγέτη και των εκπαιδευτικών σε μια σχολική μονάδα, θα μπορούσε να συνεισφέρει αποτελεσματικά στην αντιμετώπιση τόσο των προβλημάτων της καθημερινότητας όσο και στην περίπτωση απαιτητικών και πρωτόγνωρων συνθηκών (π.χ. οικονομικές κρίσεις, περιπτώσεις πανδημίας κτλ.). Η έρευνα έχει καταδείξει ότι η ανάπτυξη σχέσεων εμπιστοσύνης σε σχολικά συγκείμενα διασφαλίζει, μεταξύ άλλων, υψηλά μαθησιακά αποτελέσματα, την παρουσία Οργανωσιακών Συμπεριφορών, την αλλαγή και την προσαρμογή, τη συνεργασία, το θετικό και υποστηρικτικό σχολικό κλίμα, την ενισχυμένη συλλογική επάρκεια, τη συνεχή επαγγελματική μάθηση, την ανεμπόδιστη οριζόντια και κάθετη επικοινωνία και την αυξημένη υπευθυνότητα και επαγγελματισμό από μέρους των εκπαιδευτικών. Το παρόν άρθρο στοχεύει, μέσα από την αποδελτίωση της βιβλιογραφίας, να αναδείξει πώς η εμπιστοσύνη διευκολύνει τους σχολικούς ηγέτες και τους εκπαιδευτικούς να αντιμετωπίσουν με επιτυχία τις προκλήσεις που αναδύονται τόσο σε καθημερινή βάση, αλλά και σε περιόδους αβεβαιότητας και αστάθειας (π.χ. περίοδος Covid-19).
Η γυναίκα εκπαιδευτικός στα σχολικά εγχειρίδια του μαθήματος των Νέων Ελληνικών της Δευτεροβάθμιας Εκπαίδευσης, από το 1985 έως το 2018
Authors: Ασπιώτη Άννα 
Published: January 2025

Σκοπός της παρούσας έρευνας ήταν η ανάδειξη μέσω της μελέτης, της οριοθετημένης στερεοτυπικά, θέσης της γυναικείας εκπαιδευτικής παρουσίας, στα σχολικά εγχειρίδια της Νεοελληνικής Γραμματείας στη Δ/θμια Εκπαίδευση, από το 1985 έως το 2018.
Η μελέτη στηρίχθηκε μεταξύ άλλων, στην ιστορική καταγραφή των ελλαδικών εξελίξεων, από τις αρχές του 21ου αιώνα έως το 2018, καθώς και στην αντίστοιχη μεταπολεμική επιστημονική και πνευματική δημιουργία, γνωρίζοντας το ρόλο που αυτά παίζουν στη συγγραφή σχολικών εγχειριδίων και στη διαπαιδαγώγηση- αγωγή των μαθητών/τριών.
Επιπρόσθετα, διερευνήθηκαν οι Μεταρρυθμίσεις στο χώρο της Παιδείας , τα σχολικά βιβλία, η μόρφωση των γυναικών και η συμβολή τους στο χώρο της παιδείας, η παρουσία τους στα κοινωνι-κοπολιτικά και πολιτισμικά δρώμενα κατά την προαναφερθείσα περίοδο, αλλά και η ευρωπαϊκή διάσταση της εκπαίδευσης, όπως αυτή αντλείται από την "αρχή της επικουρικότητας", τη Συνθήκη του Μάαστριχ (1987) έως και τη Συνθήκη της Λισαβόνας (2007).
Αντικείμενο της έρευνας αποτέλεσαν σαράντα δυο (42) σχολικά εγχειρίδια της Νεοελληνικής Γραμματείας και διδακτικών πακέτων (Θεματικοί Κύκλοι -Τετράδια Εργασιών), Δ/θμιας Εκπ/σης, της χρονικής περιόδου 1985-2018.
Η τελική « εικόνα»-συμπέρασμα που αποκρυσταλλώθηκε από το υπό έρευνα υλικό, ήταν η ανεπαίσθητη παρουσία της γυ-ναίκας εκπαιδευτικού και όπου υπήρχε ισχνή και περιθωριοποιημένη πα-ρουσία της, ξετυλιγόταν ο "μίτος" των έμφυλων στερεοτυπικών χαρακτηριστικών.
Επίσης, σε όσα κείμενα παρουσιαζόταν ως ενδοκειμενική πρωταγωνίστρια, αφορούσαν νεότερα πολυτροπικά κείμενα (εφημερίδες, βιογραφικά σημειώματα, μαθητικά περιοδικά και σχολικές ανα-κοινώσεις), που ανθολογούνταν κυρίως, σε σχολικά εγχειρίδια από το 2000 και εφεξής. Χαρακτη-ριστικό τους ήταν, ότι στην πλειοψηφία τους ήταν εγχειρίδια Νεοελλη-νικής Γλώσσας, ενώ τα Κείμενα Νεοελληνικής Λογοτεχνίας, υστερούσαν ως προς τα παραπάνω στοιχεία με πιο συντηρητικές παρουσιάσεις σε όλα τα επίπεδα, γυναικών εκπαιδευτικών.
Αξιοσημείωτο επιπρόσθετα, είναι το γεγονός πως το ανθολογούμενο υλικό παραμένει ίδιο, εκτός κάποιων αναθεωρήσεων των εγχειριδίων από το 2006 και εφεξής, βασιζόμενες στις επιταγές της ευρωπαϊκής εκπαιδευτικής πολιτικής, όπου παρου-σιάστηκε έντονα η ανάγκη της ανανέωσης του περιεχομένου των σχολικών εγχειριδίων, και της συμβολής των εκπαιδευτικών ως φορείς κοινωνι-κοϊδεολογικών προτύπων, για την ουσιαστική προώθηση της ισότητας και της ανανέωσης των Αναλυτικών Προγραμμάτων που φαίνεται όμως, δεν κατάφεραν την αναμενόμενη συμβολή τους στην προαγωγή της ισότητας των δυο φύ-λων στην εκπαιδευτική διαδικασία.
Modern treatment methods in atopic dermatitis - literature overview
Authors: Borowska-Łygan Martyna , Tomaszewski Jakub , Urban Wojciech , Strużek Konrad , Biłogras Jan , Karamus Kornelia , Rejmak Rafał Wojciech 
Published: January 2025

Introduction and aim: Atopic dermatitis (AD) is a chronic inflammatory skin disease. It is characterised by periods of exacerbation and remission of symptoms such as pruritus, dry skin and eczematous lesions with characteristic morphology. The aim of this study is to present the current state of knowledge on new treatments for atopic dermatitis.
Review methods: The review was based on publicly available PubMed and Google Scholar databases from 2020 to 2024 using the following phrases: atopic dermatitis, treatment of atopic dermatitis, diagnosis of atopic dermatitis, epidemiology, biological treatment of atopic dermatitis, JAK inhibitors, stem cells, dermatitis.
Brief description of the state of the art: Atopic dermatitis is a disease whose mechanism of origin is incompletely understood.It involves interactions between genotype, environment, and the immune system, and is largely related to the T-cell response. The main symptom is pruritus and dry skin leading to lichenification or exfoliation of the epidermis, which characterise the chronic form. Diagnosis is confirmed by clinical criteria such as skin lesions characteristic of AD, a family predisposition to allergic disease and a full history and skin tests. Treatment focuses on managing the symptoms associated with the disease and improving the patient's quality of life using mainly corticosteroids, calcineurin inhibitors and antihistamines. Recent studies show positive effects of treatment with biologic drugs, JAK inhibitors, stem cells and provide great hope towards the development of treatments for atopic dermatitis.
Summary: The authors emphasise the need for further research towards the development of promising, innovative treatments for atopic dermatitis in order to significantly improve patients' quality of life.
The Role of Route-Level Decisions in the Efficiency and Resilience of Airline Operations: Evidence from the Wright Amendment Repeal
Authors: Ahuja Vishal , Alan Yasin , Arıkan Mazhar 
Published: January 2025

Problem definition: We study the impact of an airline’s route-level decisions on the efficiency and resilience of its operations. Methodology/results: Our study uses a proprietary passenger-level data set provided by Southwest Airlines and takes advantage of a regulatory change, the Wright Amendment repeal. The Wright Amendment restricted nonstop service between Dallas Love Field Airport (DAL) and most major destinations. Its repeal led to significant changes in Southwest’s service offerings at DAL. We use a difference-in-differences framework to quantify the impact of the repeal on the scheduled travel times and long travel delays at the passenger level, which serve as proxies for efficiency and resilience, respectively. We show that the repeal’s impact varies widely across destinations. Although Southwest introduced nonstop service to some destinations but not others after the repeal, this decision alone does not sufficiently explain the observed heterogeneity. As such, we develop two route-level metrics—route inefficiency and route resilience—to explain the heterogeneous impact of the repeal on different destinations. Moreover, our counterfactual analysis shows that reallocating connecting passengers with small itinerary buffers to alternative itineraries can result in major resilience improvements without significantly deteriorating efficiency. Managerial implications: Our findings are robust to alternative empirical specifications and have important implications for practitioners and regulators. Specifically, our study not only sheds light on the operational consequences of airlines’ route-level decisions but also demonstrates how managers can effectively manage the efficiency-resilience tradeoff for connecting passengers. Our study also implies that regulators can add more transparency to airline operations by providing public access to passenger-level data. Supplemental Material: The online appendix is available at https://doi.org/10.1287/msom.2023.0070 .
Robotic total knee arthroplasty safely reduces length of stay in an Asian public healthcare system
Authors: Chan Kai C. A. , Cheung Amy , Chan Ping-Keung , Luk Michelle H. , Chiu Kwong Y. , Fu Henry 
Published: January 2025

AimsAround the world, the emergence of robotic technology has improved surgical precision and accuracy in total knee arthroplasty (TKA). This territory-wide study compares the results of various robotic TKA (R-TKA) systems with those of conventional TKA (C-TKA) and computer-navigated TKA (N-TKA).MethodsThis is a retrospective study utilizing territory-wide data from the Clinical Data Analysis and Reporting System (CDARS). All patients who underwent primary TKA in all 47 public hospitals in Hong Kong between January 2021 and December 2023 were analyzed. Primary outcomes were the percentage use of various robotic and navigation platforms. Secondary outcomes were: 1) mean length of stay (LOS); 2) 30-day emergency department (ED) attendance rate; 3) 90-day ED attendance rate; 4) 90-day reoperation rate; 5) 90-day mortality rate; and 6) surgical time.ResultsA total of 8,492 knees from 7,746 patients were included in the study. Overall robotic use had risen to 20.4% (2023 Q3 to Q4: 355/1,738) by the end of 2023, with Mako being the most popular at 10.3% (179/1,738). R-TKA had the shortest mean LOS compared with N-TKA and C-TKA (5.5 vs 6.3 and 7.1 days, respectively; p < 0.001). Only Mako (9.7%) demonstrated reduced 90-day ED attendance compared to C-TKA (13.1%; p = 0.009), Cori/Navio (15.0%; p = 0.005), and Rosa (16.4%; p < 0.001). No differences in 90-day reoperation rate and mortality were observed between all groups. Mean surgical times were longer in R-TKA groups by 20.6 minutes (p < 0.001).ConclusionR-TKA use has increased in recent years, and has been shown to reduce hospital stay despite having a slightly longer surgical time, proving a promising candidate to alleviate the burden on healthcare systems. Individual differences between R-TKA systems contributed to variable clinical outcomes.Cite this article: Bone Jt Open 2024;6(1):12–20.
An exploratory review of resiliency assessments after brain injury
Authors: Griffioen Janna , Gingrich Nicole , Pollock Courtney L. , Schmidt Julia 
Published: January 2025

Background
People with brain injury can have lower resiliency compared to the general public. Yet, resiliency facilitates positive processes to negotiate adversity after brain injury. Therefore, measuring resiliency after a brain injury is important.

Objective
The review aimed to (1) identify self-report resiliency outcome measures for use with people after acquired brain injury, using the process-based Traumatic Brain Injury Resiliency Model as the guiding conceptual framework, and (2) summarize the psychometric properties of the identified outcome measures and the utility of these measures in clinical rehabilitation.

Method
The COSMIN guidelines for systematic reviews were followed to ensure appropriate reporting for each measure. Databases CINAHL, EMBASE, Medline, and PsychINFO were searched and independently reviewed by two people. Articles providing data on psychometric properties for measures of resilience for people with brain injury were retrieved. Psychometric properties and clinical utility (number of items, scoring details) were summarized.

Results
Thirty-two articles were retrieved, including nine measures of resiliency: Acceptance and Action Questionnaire–Acquired Brain Injury, Confidence after Stroke Measure, Connor-Davidson Resilience Scale, Daily Living Self-Efficacy Scale, General Self-Efficacy Scale, Participation Strategies Self-Efficacy Scale, Resilience Scale, Robson Self-Esteem Scale, and the Stroke Self-Efficacy Questionnaire. All measures have acceptable to excellent psychometric properties in accordance with the COSMIN guidelines.

Conclusion
There are established measures of resiliency in brain injury rehabilitation. Future work may explore use of these measures in a clinical context and implementation of rehabilitation goals for improving resiliency after brain injury.
Association between age-related hearing loss and depression: A systematic review and meta-analysis
Authors: Li Fuyao , Jin Meiling , Ma Tianyi , Cui Chunlian 
Published: January 2025

Introduction
This meta-analysis examined the relationship between age-related hearing loss (ARHL) and depression in older adults, and further explored whether this relationship is moderated by age and gender.

Methods
We searched in 4 English databases: PubMed, Embase, Web of Science, and Cochrane Library. Ultimately, we identified 9 studies, involving 3 cohort studies and 6 cross-sectional studies. We used Hedges’ g as the effect size, and all pooled analyses were performed using random-effects models.

Results
ARHL patients had higher depressive symptom scores than non-ARHL older adults (g = 0.52). When divided into subgroups based on study type, a large effect size was demonstrated in the cross-sectional study group (g = 0.68) and was not statistically different in the cohort study group (g = 0.06). Meta-regression results showed that the effect size of depression in older adults with ARHL was significantly associated with the percentage of females (t = 5.97, p = 0.000) and not significantly associated with age (t = 0.94, p = 0.364).

Conclusions
Patients with ARHL are more likely to be depressed than older adults with normal hearing, and this relationship is influenced by the gender of the patients.
Early neutrophil activation and NETs release in the pristane-induced lupus mice model
Authors: Carrasco Solange , Liphaus Bernadete L. , Peixoto Tatiana Vasconcelos , Lima Thais Martins , Ariga Sueli Kunimi Kubo , Jesus Queiroz Zelita Aparecida , de Matos Lobo Thays , Catanozi Sergio , Rodrigues Letícia Gomes , Filho Antônio Santos , Teodoro Walcy Rosolia , Velosa Ana Paula Pereira , Levy Débora , Soriano Francisco Garcia , Goldenstein-Schainberg Cláudia 
Published: January 2025

Background
NETosis is recognized as an important source of autoantigens. Therefore, we hypothesized whether the pristane-induced lupus mice model shows early activation of neutrophils, the presence of low-density granulocytes (LDGs), and neutrophil extracellular traps (NETs) release, which could contribute to the development of a lupus phenotype.

Methods
Twelve female wild-type Balb/c mice were intraperitoneally injected with pristane (n = 6; pristane group) or saline (n = 6; control group). Five days after the injection, blood, peritoneal lavage, bone marrow, and spleen samples were collected for flow cytometry analyses of activated neutrophils (Ly6G+CD11b+), LDGs (CD15+CD14low), and NETs release (Sytox Green+).

Results
The pristane-induced mice group had a significantly increased number of blood activated neutrophils and LDGs as well as NETs released by these cells compared to the saline-injected control group and the basal values determined 12 days before the injection. The pristane group also had a significantly increased number of activated neutrophils, LDGs, and NETs released compared to the control group for the peritoneal lavage and bone marrow, except total cell count in spleen.

Conclusions
We demonstrated early changes in the innate immune response such as an increased number of activated neutrophils and LDGs and mainly increased NETosis in the pristane-induced mice model which may be considered as the primary event triggering lupus development.
Disability and depression among stroke survivors attending rehabilitation facilities at three designated tertiary care hospitals in Bangladesh: A cross-sectional study
Authors: Islam Mohammad Jahirul , Ahmed Sohel , Kamrul Islam Khandaker Md , Tina Progya Laboni , Nath Ayon Deb , Biswas Nipa , Islam Md Shafiqul , Dey Shikder Bikash Juty , Al Mamun Muhammed Abdullah , Yasmin Nasima , Chakraborty Shishir Ranjan 
Published: January 2025

Background
Poststroke depression (PSD) is a highly prevalent and serious mental health condition affecting a significant proportion of stroke survivors worldwide. While its exact causes remain under investigation, managing PSD presents a significant challenge.

Aim
This study aimed to evaluate the prevalence and predictors of depression among Bangladeshi stroke victims.

Methods
A cross-sectional study was carried out with 725 stroke victims who were receiving medical care at three designated tertiary care hospitals in Sylhet from January to December 2023. Depression and disability were measured using the Patient Health Questionnaire-9 and the Modified Rankin Scale. Logistic regression analysis was employed to examine the predictors linked to depression.

Results
According to the study, 80.8% of individuals had moderate to severe disability, and 58.1% of them experienced a moderate to severe level of depression. Individuals who had hemorrhagic stroke (AOR 1.31, 95% CI: 0.77–2.25), repeated episodes (AOR 3.41, 95% CI: 1.89–6.14), tobacco use (AOR 1.76, 95% CI: 1.16–2.67), or coexisting health conditions (AOR 1.68, 95% CI: 1.00–2.82) exhibited elevated levels of depression. Participants whose medical expenses covered by relatives or others were six times more likely to experience depressive symptoms (AOR 6.32, 95% CI: 1.61–24.76). Individuals who did not receive rehabilitation services had two times greater odds of being depressed (OR 1.85, 95% CI: 1.23–2.77, p = 0.003). Consequently, individuals with low functional status had eleven times greater levels of depression (AOR 11.03, 95% CI: 7.14–17.04).

Conclusion
More than half of the participants in this present study reported moderate to extreme levels of depression which is a serious health issue among Bangladeshi stroke survivors. Understanding the predictors of depression linked to stroke could enhance the effectiveness of therapeutic interventions for this condition. In addition, multidisciplinary teams should work collaboratively to address this serious issue.