bluuebunny/crossref_metadata_2025_split huggingface dataset:
„Gewichtige Anhaltspunkte“ bei Verdacht auf Kindesmisshandlung – eine Befragung in Deutschland tätiger Ärzte und Psychotherapeuten
Authors: Berthold Oliver , Jud Andreas , Jarczok Marion , Heimann Tobias , Fegert Jörg , Clemens Vera 
Published: July 2021

Zusammenfassung
Hintergrund Es gibt Hinweise, dass Fachkräfte im Gesundheitswesen unsicher in Bezug auf die rechtlichen Rahmenbedingungen sind, wenn sie in Kontakt mit Kindern kommen, bei denen der Verdacht auf eine Kindeswohlgefährdung aufgekommen ist. Hieraus könnte sich ein inkonsistenter Umgang mit derartigen Fällen ergeben, der im schlimmsten Fall zu einer weiteren Gefährdung betroffener Kinder führt. Mit der vorliegenden Studie sollte eine empirische Grundlage geschaffen werden, um die Kenntnis des Rechtsrahmens bei Fachkräften im Gesundheitswesen zu untersuchen.
Methoden Es erfolgte eine Befragung in Deutschland tätiger Kinder- und Jugendmediziner, Kinderchirurgen, Kinder- und Jugendpsychiatern sowie psychologischer und Kinder- und Jugendlichenpsychotherapeuten zur Kenntnis der Rahmenbedingungen.
Ergebnisse In allen Berufsgruppen fühlt sich eine Mehrzahl der Befragten unsicher in der Anwendung des Rechtsrahmens im Alltag. Nur eine Minderheit kann die rechtlichen Regelungen des Bundeskinderschutzgesetzes korrekt wiedergeben. Erfahrung mit Kinderschutzfällen verdoppelte die Wahrscheinlichkeit, den Rechtsrahmen korrekt wiederzugeben. Der Besuch von Fortbildungen zeigte hingegen keinen Einfluss.
Schlussfolgerung Die Kenntnisse zum rechtlichen Rahmen bei Kindswohlgefährdung sind gering. Es gilt, insbesondere für Fachkräfte mit geringer Erfahrung in Kinderschutzfällen, die Weiterbildung zu verbessern und niedrigschwellige Angebote zur Beratung anzubieten.
Untersuchungen zur „Wirkung“ von Selbsterfahrung in
der Psychotherapieausbildung – Ein systematisches
Review
Authors: Strauß Bernhard , Taeger Dolinda 
Published: July 2021

Zusammenfassung
Hintergrund Der Nutzen von Selbsterfahrung bzw. eigener Psychotherapie als
Bestandteil der Psychotherapieausbildung wird immer wieder hinterfragt. Im
deutschen System wird Selbsterfahrung sowohl in der psychosozialen
ärztlichen Weiterbildung wie auch im Kontext des Psychotherapiestudiums
und der nachfolgenden Weiterbildung weiterhin ein zentraler Bestandteil der
Weiterbildung bleiben.
Ziel der Arbeit Erstellung einer Übersicht über Wirkungen
von Selbsterfahrung in der Psychotherapieausbildung.
Material und Methode Systematisches Literaturreview von Studien zwischen
2005 und 2020. Literatursammlung über Datenbanken, Vorabrecherche und
Durchsicht von Literaturverzeichnissen thematisch verwandter Arbeiten. Auswahl
anhand vorab festgelegter Ein- und Ausschlusskriterien.
Ergebnisse 13 Studien wurden ausgewählt. Die relevanten Befunde
wurden studienübergreifend zu 7 Ergebnisvariablen zusammengefasst. Es
zeigen sich überwiegend positive Wirkungen von Selbsterfahrung im
Hinblick auf interpersonale Fähigkeiten, Selbstwahrnehmung, das Wissen
und Verständnis therapeutischer Arbeit, Wohlbefinden und Entlastung.
Zufriedenheit und die Anerkennung der subjektiven Bedeutung für den
Kompetenzerwerb sind ausgeprägter als Berichte über intensive
Emotionen und Belastungen.
Schlussfolgerung Selbsterfahrung weist offenbar einen hohen Wert
für die berufliche Entwicklung angehender Therapeuten auf und sollte
daher auch ein fester Ausbildungsbestandteil sein. Eine
regelmäßige Evaluation ist allerdings zu empfehlen. In
zukünftiger Forschung sollten neben den bisher vorherrschenden
Selbstberichtsverfahren vermehrt auch objektive Erhebungsmethoden verwendet, die
Repräsentativität der Stichproben gesteigert und Langzeiteffekte
untersucht werden.
Vergleich von Schaumstoffbandagen mit Standard-Unterpolsterung in der Komplexen Physikalischen Entstauungstherapie der Phase I des sekundären Armlymphödems – eine prospektive RCT
Authors: Kornappel Simone , Liebl Max Emanuel , Stroux Andrea , Glöckner Frauke , Reißhauer Anett 
Published: July 2021

Zusammenfassung
Hintergrund In der Entstauungsphase der Komplexen Physikalischen Entstauungstherapie des Lymphödems (KPE Phase I) werden verschiedene Untermaterialien eingesetzt, um die Anlage der Kurzzugbinden zu stabilisieren und die Haut zu schützen. Eine neuartige Form der Unterpolsterung bieten mit Baumwolle umnähte Schaumstoffbandagen. Deren Therapieeffekte sind jedoch bislang nicht untersucht.
Material und Methoden Prospektive, randomisierte Nichtunterlegenheitsstudie an Proband/innen mit sekundärem Armlymphödem. Die Kontrollgruppe erhielt eine KPE Phase I mit Standardtherapie (Unterpolsterung aus Schlauchverband und Wattebinde), die Interventionsgruppe erhielt die KPE Phase I mit Schaumstoffbandagen (SC). Primärer Endpunkt war das optoelektronisch gemessene Volumen. Zudem wurde die Umfangsreduktion ermittelt und die Patientenperspektive erfragt.
Ergebnisse n=30 Proband/innen konnten analysiert werden. SC zeigten einen signifikant größeren Effekt in der Volumenreduktion (p=0,026; 95% Kl [−207,9;+7,4]). Bei apriori definiertem Äquivalenzbereich von±50 ml sind SC der Referenztherapie nicht unterlegen. Die Patienten bewerteten die Abnahme des Spannungsgefühls sowie den Tragekomfort bei SC signifikant besser (p=0,026 sowie p=0,003).
Schlussfolgerung Schaumstoffbandagen sind Standardpolstermaterial nicht unterlegen. Sie können in der Entstauungsphase von Lymphödemen als alternatives Unterpolsterungsmaterial eingesetzt werden. Die Daten liefern Hinweise darauf, dass sie die Reduktion des Ödemvolumens im Vergleich mit bislang verwendeten Untermaterialien verbessern können und das Spannungsgefühl durch sie deutlicher reduziert werden kann.
The New Way to Exercise? Evaluating an Innovative Heart-rate-controlled Exergame
Authors: Ketelhut Sascha , Röglin Lisa , Kircher Eva , Martin-Niedecken AnnaLisa , Ketelhut Reinhard , Hottenrott Kuno , Ketelhut Kerstin 
Published: July 2021

AbstractExergames may offer novel opportunities to expand physical activity. Most games, however, only result in low to moderate-intensity activities that are too low to allow relevant physical adjustments. In the present study, the exercise intensity of a new, heart rate controlled, functional fitness game was assessed. 28 subjects (aged 24.8±3.8 yrs; 46% female; BMI 23.2±2.3 kg/m2) were enrolled in this study. VO2max and maximal heart rate (HRmax) were assessed during a maximal graded exercise test on a treadmill and compared with the oxygen consumption (VO2) and heart rate (HR) during a game in the ExerCube.In the ExerCube, the subjects reached a peak HR of 187.43±9.22 bpm, which corresponds to 96.57±3.64% of their HRmax. The mean HR throughout the game was 167.11±10.94 bpm, corresponding to 86.07±4.33% of HRmax. VO2peak reached 41.57±5.09 ml/kg/min during the game in the ExerCube, which corresponds to 84.75±7.52% of VO2max. The mean VO2 consumption during the game reached 32.39±4.04 ml/kg/min, which corresponds to 66.01±5.09% of VO2max. The ExerCube provides a form of vigorous physical exercise. Due to its playful, immersive, and motivating nature, the ExerCube seems to be a promising tool to facilitate physical activity.
Influence of Spinal Cord Stimulation on Insulin Sensitivity in Chronic Pain Patients
Authors: Morgalla Matthias H. , Fritschle Hannah , Vosseler Andreas , Benkendorff Charlotte , Lamprinou Apostolia , Heni Martin , Fritsche Andreas 
Published: July 2021

Abstract
Background and Objective This prospective, sham-controlled, randomized, cross-over study (NCT03637075), was designed to test the hypothesis that spinal cord stimulation (SCS) for the treatment of pain can also improve glucose metabolism and insulin sensitivity when compared to sham stimulation.
Methods Ten non-diabetic participants (5 females, mean age 48.8 years) who had an SCS system implanted for the treatment of chronic neuropathic pain were studied. Whilst applying a hyperinsulinemic-euglycemic clamp, sham-stimulation and tonic stimulation were performed for 45 min (n=4) or 60 min (n=6) in each case randomly. The insulin sensitivity index and pain levels were determined. A second investigation, BurstDR stimulation was also conducted and the result was compared to that of sham stimulation (cross-over design).
Results The insulin sensitivity improved significantly under the tonic stimulation when compared to the sham stimulation (p=0.037). BurstDR stimulation independently did not lead to a significantly improved insulin sensitivity compared to that after sham stimulation (p=0.16). We also examined the pain during the test and found no significant difference between sham and tonic stimulation (p=0.687).
Conclusion The results of this study show that tonic stimulation used for the treatment of pain could also improve glucose metabolism and insulin sensitivity. Further investigations are required to investigate the clinical relevance of the role of glucose metabolism in diabetic chronic pain participants and its underlying mechanisms.
Placental Transfusion, Timing of Plastic Wrap or Bag Placement, and Preterm Neonates
Authors: Engle William , Lien Izlin , Benneyworth Brian , Tully Jennifer Stanton , Barbato Alana , Kunkel Melissa , Boon Win , Waheed Saira , Hoesli Sandra , Chua Rosario , Singhal Abhay , Buchh Basharat , Winchester Paul , Guilfoy Veronica , Proctor Cathy , Sanchez Mario , Joyce Jeffrey , He Tian 
Published: July 2021

Objective Compare delivery room practices and outcomes of infants born at less than 32 weeks' gestation or less than 1,500 g who have plastic wrap/bag placement simultaneously during placental transfusion to those receiving plastic wrap/bag placement sequentially following placental transfusion.
Study Design Retrospective analysis of data from a multisite quality improvement initiative to refine stabilization procedures pertaining to placental transfusion and thermoregulation using a plastic wrap/bag. Delivery room practices and outcome data in 590 total cases receiving placental transfusion were controlled for propensity score matching and hospital of birth.
Results The simultaneous and sequential groups were similar in demographic and most outcome metrics. The simultaneous group had longer duration of delayed cord clamping compared with the sequential group (42.3 ± 14.8 vs. 34.1 ± 10.3 seconds, p < 0.001), and fewer number of times cord milking was performed (0.41 ± 1.26 vs. 0.86 ± 1.92 seconds, p < 0.001). The time to initiate respiratory support was also significantly shorter in the simultaneous group (97.2 ± 100.6 vs. 125.2 ± 177.6 seconds, p = 0.02). The combined outcome of death or necrotizing enterocolitis in the simultaneous group was more frequent than in the sequential group (15.3 vs. 9.3%, p = 0.038); all other outcomes measured were similar.
Conclusion Timing of plastic wrap/bag placement during placental transfusion did affect duration of delayed cord clamping, number of times cord milking was performed, and time to initiate respiratory support in the delivery room but did not alter birth hospital outcomes or respiratory care practices other than the combined outcome of death or necrotizing enterocolitis.
Key Points
Outcomes of Shoulder Functions in Spinal Accessory to Suprascapular Nerve Transfer in Brachial Plexus Injury: A Comparison between Anterior and Posterior Approach
Authors: Maurya Sanjay , Renganathan Gopi , R. Venkatnarayanan , Bharti Rajiv 
Published: July 2021

Abstract
Background Restoration of shoulder functions is important in brachial plexus injury (BPI). The functional outcomes of spinal accessory nerve (SAN) to suprascapular nerve (SSN) transfer by the anterior supraclavicular approach and the posterior approach is a matter of debate. This article aims to compare the outcomes of the shoulder functions by the SAN to the SSN transfer using the two approaches.
Methods Retrospective data was collected in 34 patients who underwent SAN to SSN transfer from January 2016 to June 2018. Group A included 16 patients who underwent nerve transfers by anterior approach, and Group B included 18 patients who underwent nerve transfers by posterior approach. Functional outcomes were measured by grading the muscle power as per the British Medical Research Council (MRC) grading (graded as M) and the range of motions (ROM) of the shoulder at 6 months and 18 months.
Results Early recovery was seen in group B with 7 patients (39%) showing M1 abduction power at 6 months as compared with one patient (6%) in group A . This difference was statistically significant (p value = 0.04). At 18 months, 10 patients (62%) in group A had good recovery (MRC grade ≥3), while 13 patients (72%) in group B had a good recovery. This difference was not found to be statistically significant (Fisher exact test p value = 0.71) There was no statistical difference in the outcomes of ROM in shoulder abduction, external rotation, and motor power at 18 months of follow-up.
Conclusions Early recovery was observed in the posterior approach group at 6 months, however, there was no significant difference in the outcomes of shoulder functions in muscle power and ROM in the two groups at 18 months of follow-up.
Collaboration matters: capacity building, up-scaling, spreading, and sustainability in citizen-generated data projects
Authors: Balestrini Mara , Kotsev Alexander , Ponti Marisa , Schade Sven 
Published: July 2021

AbstractProjects producing citizen-generating data (CGD) to provide evidence and to drive change have increased considerably in the last decade. Many of these initiatives build on multi-actor collaboration and are often supported by non-governmental organisations (NGOs), the public sector, businesses or community-based organisations. The joint efforts of these actors are often necessary to provide the resources and the support that citizens need to produce data. In return, organisations can harness the data to support their objectives. The recent growth (or up-scaling) of CGD projects has created opportunities, as well as challenges for capacity building and sustainability. These challenges can affect the continuity and effectiveness of these initiatives and, in turn, the quality and utility of collected data. This paper analyses two CGD projects to consider their social implications and the measures necessary to increase their capacity, up-scaling, spreading, and sustainability. The case studies on noise monitoring and invasive alien species describe, respectively, a bottom-up approach at city level and a top-down approach at the European level. Regardless of the approach, capacity building requires a process of infrastructuring that engages different actors, responds to matters of concern, assesses community capacities and needs, and develops a vision and action plan. Further, the appropriation and repurposing of technical systems is required to scale up and spread CGD projects. In this process, participants’ activities are shaped by technologies, while the meaning and effects of technologies are shaped through participants’ activities.
Estimation of solid-state sintering and material parameters using phase-field modeling and ensemble four-dimensional variational method
Authors: Ishii Akimitsu , Yamanaka Akinori , Miyoshi Eisuke , Okada Yuki , Yamamoto Akiyasu 
Published: July 2021

Abstract
Sintering is a fundamental technology for powder metallurgy, the ceramics industry, and additive manufacturing processes such as three-dimensional printing. Improvement of the properties of sintered materials requires prediction of their microstructure using numerical simulations. However, the physical values and material parameters used for such predictions are generally unknown. Data assimilation (DA) enables the estimation of unobserved states and unknown material parameters by integrating simulation results and observational data. In this paper, we develop a new model that couples an ensemble-based four-dimensional variational (En4DVar) DA with a phase-field model of solid-state sintering (En4DVar-PF model) to estimate the state of the sintered material and multiple unknown material parameters. The developed En4DVar-PF model is validated by numerical experiments called twin experiments, in which a priori assumed-true initial state and multiple material parameters are estimated. The results of the twin experiments demonstrate that, using only three-dimensional morphological data of the sintered microstructure, our developed En4DVar-PF model can simultaneously and accurately estimate the particle shape, distribution of grain boundaries, and material parameters, including diffusion coefficients and mobilities related to grain boundary migration. Furthermore, our work identifies criteria for determining appropriate DA conditions such as the observational time interval required to accurately estimate the material parameters using our developed model. The developed En4DVar-PF model provides a promising framework to obtain unobservable states and difficult-to-measure material parameters in sintering, which is crucial for the accurate prediction of sintering processes and for the development of superior materials.
Day-ahead Low-Carbon Economical Dispatch of Integrated Energy System With CSP and ORC Based on Improved Imperialist Competitive Algorithm
Authors: Zhang Nenghan , Jian Xiyan , Ding Yibo , Wang Yufeng , Chen Lei 
Published: July 2021

Abstract
In this paper an improved imperialist competitive algorithm(ICA) is used for day-ahead low-carbon economic dispatch of the integrated energy system(IES) with CSP and ORC. In order to enhance the utilization efficiency of different types of energy in IES, this paper introduces a concentrating solar power(CSP) plant to act as a power unit and an organic Rankine cycle(ORC) plant to decouple thermoelectric coupling. Combined with the facilities like the gas turbines(GT), power to gas(P2G), photovoltaic power(PV), etc. in IES, a day-ahead low-carbon economical dispatch model of IES is proposed to minimize the system cost. In the paper, the system cost is optimized by using the improved ICA. The analysis of the results of the example verifies that the proposed model is reliable and effective.
Metals and Breast Cancer Risk: A Prospective Study Using Toenail Biomarkers
Authors: Niehoff Nicole M , O’Brien Katie M , Keil Alexander P , Levine Keith E , Liyanapatirana Chamindu , Haines Laura G , Waidyanatha Suramya , Weinberg Clarice R , White Alexandra J 
Published: July 2021

Abstract
The role of metals in breast cancer is of interest because of their carcinogenic and endocrine-disrupting capabilities. Evidence from epidemiologic studies remains elusive, and prior studies have not investigated metal mixtures. In a case cohort nested within the Sister Study (enrolled in 2003–2009; followed through September 2017), we measured concentrations of 15 metals in toenails collected at enrollment in a race/ethnicity-stratified sample of 1,495 cases and a subcohort of 1,605 women. We estimated hazard ratios and 95% confidence intervals for each metal using Cox regression and robust variance. We used quantile g-computation to estimate the joint association between multiple metals and breast cancer risk. The average duration of follow-up was 7.5 years. There was little evidence supporting an association between individual metals and breast cancer. An exception was molybdenum, which was associated with reduced incidence of overall breast cancer risk (third tertile vs. first tertile: hazard ratio = 0.82, 95% confidence interval: 0.67, 1.00). An inverse association for antimony was observed among non-Hispanic Black women. Predefined groups of metals (all metals, nonessential metals, essential metals, and metalloestrogens) were not strongly associated with breast cancer. This study offers little support for metals, individually or as mixtures, as risk factors for breast cancer. Mechanisms for inverse associations with some metals warrant further study.
Phosphate binding sites prediction in phosphorylation-dependent protein–protein interactions
Authors: Lu Zheng-Chang , Jiang Fan , Wu Yun-Dong 
Published: July 2021

Abstract

Motivation
Phosphate binding plays an important role in modulating protein–protein interactions, which are ubiquitous in various biological processes. Accurate prediction of phosphate binding sites is an important but challenging task. Small size and diversity of phosphate binding sites lead to a substantial challenge for developing accurate prediction methods.

Results
Here, we present the phosphate binding site predictor (PBSP), a novel and accurate approach to identifying phosphate binding sites from protein structures. PBSP combines an energy-based ligand-binding sites identification method with reverse focused docking using a phosphate probe. We show that PBSP outperforms not only general ligand binding sites predictors but also other existing phospholigand-specific binding sites predictors. It achieves ∼95% success rate for top 10 predicted sites with an average Matthews correlation coefficient value of 0.84 for successful predictions. PBSP can accurately predict phosphate binding modes, with average position error of 1.4 and 2.4 Å in bound and unbound datasets, respectively. Lastly, visual inspection of the predictions is conducted. Reasons for failed predictions are further analyzed and possible ways to improve the performance are provided. These results demonstrate a novel and accurate approach to phosphate binding sites identification in protein structures.

Availability and implementation
The software and benchmark datasets are freely available at http://web.pkusz.edu.cn/wu/PBSP/.

Supplementary information
Supplementary data are available at Bioinformatics online.
‘Their Mum Messed Up and Gran Can’t Afford to’: Violence towards Grandparent Kinship Carers and the Implications for Social Work
Authors: Holt Amanda , Birchall Jenny 
Published: July 2021

Abstract
Child and adolescent violence towards grandparent kinship carers is a significant and yet under-researched phenomenon. This study draws on data from thirty-six in-depth interviews which include grandparent carers who are experiencing such violence, and professionals from a range of backgrounds whose work intersects with this problem. The study highlights how the kinship care context shapes the violence, its impacts and, in turn, carers’ help-seeking practices. The findings highlight that social workers must better understand the barriers that prevent grandparent kinship carers from asking for help, and improve their responses to such requests. Recommendations for social work practice include asking the right questions, engaging in effective risk assessment, taking a trauma-informed approach, avoiding the language of coercion and improving its response to grandparents’ own articulated support needs.