bluuebunny/crossref_metadata_2025_split huggingface dataset:
Formação e inserção dos coordenadores de curso no ensino médio e técnico: o contexto das Escolas Técnicas Estaduais de São Paulo
Authors: Pereira da Silva Cristiano , Prado Constantino Paulo Roberto 
Published: November 2021

A pesquisa pretendeu delinear a inserção e formação dos coordenadores de cursos de ensino médio e técnico nas Escolas Técnicas Estaduais de São Paulo, ao explorar aspectos relacionados à trajetória histórica, inserção e a formação inicial e continuada destes profissionais no âmbito de um sistema público de educação profissional, o Centro Estadual de Educação Tecnológica Paula Souza. Por meio de uma pesquisa documental e de campo do tipo survey, de abordagem qualitativa, realizada entre 128 coordenadores de cursos de 75 Etecs, insere-se na possibilidade de expansão de uma literatura ainda incipiente sobre a coordenação de cursos na educação profissional, apontando resultados sobre a formação e inserção destes sujeitos, desvelando lacunas existentes, oportunidades de formação pouco exploradas, a constituição do grupo de profissionais enfocado. Estes resultados, em relação à formação dos coordenadores de curso, destacaram a necessidade de alinhamento da formação inicial e continuada aos temas relacionados à gestão de legislação e da informação, bem como aspectos pedagógicos e gestionários das unidades escolares. Quanto à sua inserção, apontou-se a imperativa dotação e distribuição de carga horária suficiente para um melhor desempenho de suas atividades, bem como a importância dos incentivos variados ao desenvolvimento da função de coordenação. Em perspectiva, este ator emergiu como imprescindível para os processos e os resultados das escolas técnicas estaduais, desde seu primeiro reconhecimento histórico em 1988 e, posteriormente, acompanhando os movimentos de forte expansão institucional no início do século XXI.
Trajetória de vida docente e sua contribuição para a docência na educação profissional e tecnológica
Authors: Freire Rocha Cordeiro Machado Mércia , Santana Vieira Roberta Valeska 
Published: November 2021

Esta é uma pesquisa qualitativa que busca o sentido dos fenômenos a partir do significado que as pessoas lhes atribuem. Como pesquisa formação, adotamos os estudos narrativos das histórias de vida de professores para investigar o comportamento humano dando especial valor à subjetividade como conhecimento científico. Propusemo-nos a questionar de que modo a trajetória de vida do docente que atua nos cursos da Educação Profissional e Tecnológica (EPT) contribui para a sua prática pedagógica. Para a coleta de dados foram utilizados a pesquisa bibliográfica e a entrevista narrativa. Na pesquisa bibliográfica buscamos relacionar conceitos da pesquisa narrativa utilizados na construção da identidade profissional do docente da educação profissional e tecnológica e na entrevista narrativa o participante da investigação, ao narrar o vivido, pode ressignificar este tempo ao deixar transparecer o seu interior, seus desejos e frustrações. Os dados coletados através das entrevistas narrativas foram tratados por meio da análise de conteúdo fundamentada em Bardin (2011) e nos estudos de Jovchelovitch e Bauer (2002). Revisitar as memórias do passado é parte essencial da narrativa autobiográfica. Ainda que possa parecer penosa porque nos coloca frente a frente com os fracassos e as rupturas, também provoca a tomada de consciência e novas atitudes.
Educação profissional técnica e tecnológica no IFPR: a educação especial em questão
Authors: Vernaschi de Oliveira Lucilia , Raimundo Yaegashi Solange Franci , Fafarão Ruiz Nathália 
Published: November 2021

A educação especial é uma modalidade de ensino para estudantes com deficiência, Transtorno do Espectro Autista (TEA) e com altas habilidades e superdotação, matriculados nas diferentes etapas e níveis de ensino. Traçamos o objetivo de analisar ações institucionais de educação especial no Instituto Federal de Educação (IFPR) nos cursos profissionais técnicos e tecnológicos. Trata-se de uma pesquisa qualitativa, de natureza documental e bibliográfica. Inicialmente, apresentamos de forma geral a educação especial como modalidade de ensino que busca se efetivar por meio de dispositivos legais e de pressupostos teórico-metodológicos, a partir de temáticas específicas que tratam de recursos e serviços de acessibilidade no atendimento às especificidades do seu público. Na sequência, elencamos alguns dos principais documentos do IFPR que dispõem sobre a inclusão escolar, com ênfase nos direitos das pessoas que são público da educação especial. Para se compreender o que dizem as pesquisas stricto sensu acerca de investigações realizadas em diferentes campi do IFPR, realizamos busca no catálogo de teses e dissertações da Capes, e analisamos cinco trabalhos, sendo uma tese e quatro dissertações. De forma geral, os resultados apontam que a educação especial é bem amparada legalmente em nosso país, no entanto, no IFPR as práticas inclusivas se encontram em processo lento. Atualmente, dos vinte e cinco campi, apenas sete deles contam com professor de educação especial, mas nem todos têm sala de recursos multifuncional constituída, que é uma exigência preconizada pela Resolução 4/2009, ao instituir diretrizes operacionais para o atendimento educacional especializado (AEE) na educação básica.
Childhood parasitic infections and gastrointestinal illness in indigenous communities at Lake Atitlán, Guatemala
Authors: Roegner Amber , Orozco Mónica N. , Jarquin Claudia , Boegel William , Secaira Clara , Caballeros Marlin E. , Al-Saleh Lujain , Rejmánková Eliška 
Published: November 2021

Lake Atitlán has experienced a decline in water quality resulting from cultural eutrophication. Indigenous Mayans who already face disproportionate health challenges rely directly on the lake water. Our objectives were to: (1) estimate prevalence of shedding of water-borne fecal parasites among children 5 years of age and younger, (2) assess household-reported incidence of gastrointestinal illness in children, and (3) characterize water sources, treatment, and sanitation conditions in households. We hypothesized that household use of untreated lake water results in increased risk of shedding of parasites and gastrointestinal symptoms. A cross-sectional fecal sampling and physical exam of 401 children were conducted along with WASH surveys in partnership with healthcare providers in seven communities. Fecal samples were screened for Giardia lamblia and Cryptosporidium parvum, using a rapid ELISA, with a portion examined by microscope. The prevalence of parasite shedding was 12.2% (9.7% for Giardia; 2.5% for Cryptosporidium). Risk factors for Giardia shedding included age 3 years or older (3.4 odds ratio, z-stat = 2.781 p = 0.0054), low height-for-age z-score (2.3 odds ratio, z-stat = 2.225, p = 0.0216), lack of any household water treatment (2.5 odds ratio, z-stat = 2.492, p < 0.0012), and open access to household latrine (2.04 odds ratio, z-stat = 1.992, p = 0.0464). The majority (77.3%) of households reported water treatment, boiling and gravity fed filters as the most widespread practices. The vast majority of households (92%) reported usage of a latrine, while 40% reported open and shared access beyond their household. An overwhelming majority of households reported diarrhea and fever several times per year or greater, with approximately half reporting vomiting at that frequency. Lake water use was identified as a risk factor for households reporting frequent gastrointestinal symptoms (odds ratio of 2.5, 4.4, and 2.6; z-stat of 3.10, 3.65, and 3.0; p-values of 0.0021, 0.0003, and 0.0028, for diarrhea, vomiting, and fever, respectively) in children 5 years of age and younger. The frequency of gastrointestinal illness with a strong link to lake drinking water cannot be explained by the prevalence of protozoa, and risk from other enteropathogens must be explored. Improving access to water treatment and sanitation practices could substantially reduce the parasite burden faced by developing children in the region.
Doping‐Modulated Strain Enhancing the Phosphate Tolerance on PtFe Alloys for High‐Temperature Proton Exchange Membrane Fuel Cells
Authors: Li Wei , Wang Dongdong , Liu Tianyang , Tao Li , Zhang Yagang , Huang Yu‐Cheng , Du Shiqian , Dong Chung‐Li , Kong Zhijie , Li Ya‐fei , Lu Shanfu , Wang Shuangyin 
Published: November 2021

AbstractIn high‐temperature proton exchange membrane fuel cells (HT‐PEMFCs), the poisoning of Pt by phosphoric species severely affects the kinetics of the oxygen reduction reaction, which restricts their commercialized application. Herein, for the first time, the phosphate tolerance of PtFe ordered intermetallic alloys is enhanced by a doping‐modulated strain strategy via employing a low amount of Cu as a dopant to boost HT‐PEMFCs. This Cu doping facilitates the formation of compressive strain in PtFe crystals, consequently altering the electronic structure of electrocatalysts and then benefiting for weakening the adsorption energy between phosphoric acid and Pt surfaces. In addition, the high temperature phosphate adsorption tests also reveal that the dopant of Cu in Pt based electrocatalysts can improve the tolerance of phosphoric acid. The HT‐PEMFCs assembled by those cathodic electrocatalysts with the low‐Pt loading of 0.5 mgPt cm−2 achieve a preeminent peak power of 793.5 and 432.6 mW cm−2 under the condition of H2–O2 and H2–air atmosphere, respectively, or nearly 1.53 and 1.34 times higher as compared with commercial Pt/C electrocatalysts. Moreover, those electrocatalysts also exhibit robust stability under harsh condition in H2–O2 atmosphere with negligible activity loss for at least 100 h, exceeding most of other reported ORR electrocatalysts.
Colorful Transparent Silicon Photovoltaics with Unprecedented Flexibility
Authors: Kang Sung Bum , Salimzhanov Baurzhan , Park Won Jin , Jeong Myeong Hoon , Kim Ju‐Young , Choi Kyoung Jin 
Published: November 2021

AbstractIntegrated photovoltaics are regarded as next‐generation photovoltaic technologies that can generate electricity in urban areas with limited available land while also serving as aesthetic architectural elements. The criteria for integrating photovoltaics into buildings and electronic devices are flexibility, color tunability, efficiency, scalability, and stability. It is very challenging for integrated photovoltaics to demonstrate all‐around performance benefits because photovoltaic performances exist in a trade‐off relation, such as that between transparency and efficiency. Here, great all‐around transparent solar cells (TSC) featuring high flexibility and high transparency with color‐tunable solar cells are demonstrated. The TSCs exhibit an efficiency of 7.38% and 5.52% at the average visible transparencies of 45% and 60%, respectively. Moreover, by introducing a periodic hole array structure, the flexibility of TSCs is dramatically improved. The minimum bending radius decreases to 6 mm; it further decreases to 3 mm after PDMS embedding. The results of the numerical simulation show that the periodic hole array structure uniformly distributes the stress across the entire area as a self‐stress relief structure. The PDMS‐embedded TSCs demonstrate unprecedently high flexibility and long‐term stability without significant degradation even after cyclic bending deformations up to 1000 cycles and 1500 h of the standard damp heat test.
On the Optoelectronic Mechanisms Ruling Ti‐hyperdoped Si Photodiodes
Authors: García‐Hemme Eric , Caudevilla Daniel , Algaidy Sari , Pérez‐Zenteno Francisco , García‐Hernansanz Rodrigo , Olea Javier , Pastor David , del Prado Álvaro , San Andrés Enrique , Mártil Ignacio , González‐Díaz Germán 
Published: November 2021

AbstractThis work deepens the understanding of the optoelectronic mechanisms ruling hyperdoped‐based photodevices and shows the potential of Ti hyperdoped‐Si as a fully complementary metal‐oxide semiconductor compatible material for room‐temperature infrared photodetection technologies. By the combination of ion implantation and laser‐based methods, ≈20 nm thin hyperdoped single‐crystal Si layers with a Ti concentration as high as 1020 cm−3 are obtained. The Ti hyperdoped Si/p‐Si photodiode shows a room temperature rectification factor at ±1 V of 509. Analysis of the temperature‐dependent current–voltage characteristics shows that the transport is dominated by two mechanisms: a tunnel mechanism at low bias and a recombination process in the space charge region at high bias. A room‐temperature sub‐bandgap external quantum efficiency (EQE) extending to 2.5 µm wavelength is obtained. Temperature‐dependent spectral photoresponse behavior reveals an increase of the EQE as the temperature decreases, showing a low‐energy photoresponse edge at 0.45 eV and a high‐energy photoresponse edge at 0.67 eV. Temperature behavior of the open‐circuit voltage correlates with the high‐energy photoresponse edge. A model is proposed to relate the optoelectronic mechanisms to sub‐bandgap optical transitions involving an impurity band. This model is supported by numerical semiconductor device simulations using the SCAPS software.
A severe case of Bosch–Boonstra–Schaaf optic atrophy syndrome with a novel description of coloboma and septo‐optic dysplasia, owing to a start codon variant in the NR2F1 gene
Authors: Gazdagh Gabriella , Mawby Rebecca , Self Jay E. , Baralle Diana ,   Deciphering Developmental Disorders Study
Published: November 2021

AbstractBosch–Boonstra–Schaaf optic atrophy syndrome (BBSOAS) is a rare congenital syndrome characterized by a range of phenotypes including optic atrophy and intellectual disability among other features. Pathogenic variants in the NR2F1 (nuclear receptor subfamily 2 group F member 1) gene have been linked to this condition. A recent report has shown that pathogenic variants in the start codon lead to decreased expression of the NR2F1 protein and a relatively mild phenotype, similar to that seen in whole gene deletions, and due to the lack of the dominant negative effect. Here we describe a severe case of BBSOAS with an initiation codon missense variant. The developmental delay, seizures, optic atrophy are in keeping with features observed in this condition, however this is the first report to describe colobomas and septo‐optic dysplasia as associated features potentially extending the phenotype linked to BBSOAS. In addition, this is the first description of a severe phenotype linked to a de novo missense variant in the start codon of the NR2F1 gene.
Plasma amyloid beta, neurofilament light chain, and total tau in the Systolic Blood Pressure Intervention Trial (SPRINT)
Authors: Pajewski Nicholas M. , Elahi Fanny M. , Tamura Manjula Kurella , Hinman Jason D. , Nasrallah Ilya M. , Ix Joachim H. , Miller Lindsay M. , Launer Lenore J. , Wright Clinton B. , Supiano Mark A. , Lerner Alan J. , Sudduth Tiffany L. , Killeen Anthony A. , Cheung Alfred K. , Reboussin David M. , Wilcock Donna M. , Williamson Jeff D. 
Published: November 2021

AbstractIntroductionLowering blood pressure (BP) reduces the risk for cognitive impairment and the progression of cerebral white matter lesions. It is unclear whether hypertension control also influences plasma biomarkers related to Alzheimer's disease and non‐disease‐specific neurodegeneration.MethodsWe examined the effect of intensive (< 120 mm Hg) versus standard (< 140 mm Hg) BP control on longitudinal changes in plasma amyloid beta (Aβ)40 and Aβ42, total tau, and neurofilament light chain (NfL) in a subgroup of participants from the Systolic Blood Pressure Intervention Trial (N = 517).ResultsOver 3.8 years, there were no significant between‐group differences for Aβ40, Aβ42, Aβ42/Aβ40, or total tau. Intensive treatment was associated with larger increases in NfL compared to standard treatment. Adjusting for kidney function, but not BP, attenuated the association between intensive treatment and NfL.DiscussionIntensive BP treatment was associated with changes in NfL, which were correlated with changes in kidney function associated with intensive treatment.Trial Registrationclinicaltrials.gov Identifier: NCT01206062
A short review on fused deposition modeling 3D printing of bio‐based polymer nanocomposites
Authors: Mandala Radhika , Bannoth Anjaneya Prasad , Akella Suresh , Rangari Vijaya K. , Kodali Deepa 
Published: November 2021

AbstractFused deposition modeling (FDM), one among the most commonly used additive manufacturing (AM), techniques has been widely used in recent years to produce customized parts with intricate geometries, especially from thermoplastics. This method was limited in its ability to produce parts for industrial applications due to inferior properties and the poor quality of fabricated parts. Hence, researchers are being driven to discover novel materials that are viable for FDM in order to keep up with enormous demand for functional products. In the recent years, it is widely recognized that the emphasis was placed on the bio‐based polymer composite matrices rather than conventional thermoplastics due to its vital advantages that aid in the replacement of synthetic and perilous materials. On this context, this review focuses on the recent advancements in FDM printing with biomaterials. Specifically, attempts have been made to investigate and provide nutshell of 3D printing of current bio‐based nanocomposites which consist of either bio‐derived filler or polymer matrices in order to make 3D printing sustainable. The effect of fillers on the filaments and FDM based products, evolution of novel characteristics of bio nanocomposites, the printability of the developed composites and their development in leading applications were also investigated and summarized.
Development, characterization, and antioxidant evaluation of corn starch‐based composite films containing tea polyphenols
Authors: Yu Xietian , Lin Li , Mei Liping , Sun Chengyi , Zhu Zhijie , Du Xianfeng , Chen Peirong 
Published: November 2021

AbstractCorn starch/polyvinyl alcohol (PVA) composite films containing different concentrations of tea polyphenols (TP) were fabricated by casting. Scanning electron microscopy and atomic force microscopy images showed that when the TP content was less than 8%, the films were relatively uniform, but with increasing TP concentration, the films became rougher and uneven. Fourier transform infrared, 13C nuclear magnetic resonance, and X‐ray diffraction techniques were used to investigate the interactions between TP, starch, and PVA. The incorporation of TP deepened the color and increased the opacity and solubility of the films. The tensile strength and elongation at break first increased and then decreased with increasing TP content. Furthermore, the addition of TP increased the antioxidant activity of the films, specifically, their ability to scavenge 2,2‐diphenyl‐1‐picrylhydrazyl and 2,2′‐azinobis (3‐ethylberizothiazoline‐6‐sulfonic acid). The addition of TP can effectively enhance the performance of starch composite films and their potential for application in antioxidant food packaging.
Imino‐2H‐Chromene Based Derivatives as Potential Anti‐Alzheimer's Agents: Design, Synthesis, Biological Evaluation and in Silico Study
Authors: Attarroshan Mahshid , Firuzi Omidreza , Iraji Aida , Sharifi Shahrzad , Tavakkoli Marjan , Vesal Mahmmod , Khoshneviszadeh Mahsima , Pirhadi Somayeh , Edraki Najmeh 
Published: November 2021

AbstractA new series of imino‐2H‐chromene derivatives were rationally designed and synthesized as novel multifunctional agents against Alzheimer's disease. A set of phenylimino‐2H‐chromenes as well as the newly synthesized iminochromene derivatives were evaluated as BACE1, acetylcholinesterase (AChE), and butyrylcholinesterase (BuChE) inhibitors. The results indicated that among the iminochromene set, 10c bearing fluorobenzyl moiety was the most potent BACE1 inhibitor with an IC50 value 6.31 μM. In vitro anti‐cholinergic activities demonstrated that compound 10a bearing benzyl pendant was the best inhibitor of AChE (% inhibition at 30 μM=24.4) and BuChE (IC50=3.3 μM). Kinetic analysis of compound 10a against BuChE was also performed and showed a mixed‐type inhibition pattern. The neuroprotective assessment revealed that compound 11b, a phenylimino‐2H‐chromene derivative with hydroxyethyl moiety, provided 32.3 % protection at 25 μM against Aβ‐induced PC12 neuronal cell damage. In addition, docking and simulation studies of the most potent compounds against BACE1 and BuChE confirmed the experimental results.
XAS and EPR in Situ Observation of Ru(V) Oxo Intermediate in a Ru Water Oxidation Complex**
Authors: Levin Natalia , Casadevall Carla , Cutsail George E. , Lloret‐Fillol Julio , DeBeer Serena , Rüdiger Olaf 
Published: November 2021

AbstractIn this study, we combine in situ spectroelectrochemistry coupled with electron paramagnetic resonance (EPR) and X‐ray absorption spectroscopies (XAS) to investigate a molecular Ru‐based water oxidation catalyst bearing a polypyridinic backbone [RuII(OH2)(Py2Metacn)]2+. Although high valent key intermediate species arising in catalytic cycles of this family of compounds have remain elusive due to the lack of additional anionic ligands that could potentially stabilize them, mechanistic studies performed on this system proposed a water nucleophilic attack (WNA) mechanism for the O−O bond formation. Employing in situ experimental conditions and complementary spectroscopic techniques allowed to observe intermediates that provide support for a WNA mechanism, including for the first time a Ru(V) oxo intermediate based on the Py2Metacn ligand, in agreement with the previously proposed mechanism.
The discussion of the relationship between lighting and music in a lighting show
Authors: Xu Ke , Wang Yue , Jin Yan , Ju Jiaqi 
Published: November 2021

AbstractAn experiment based on physiological parameters and subjective emotional changes is designed to analyze the sound‐light fusion effects. The different effects caused by music in major and minor keys is studied. Three colorful lighting with main wavelength at 623, 537, 445 nm, respectively, as well as two white lighting with 3000 K CCT and 6000 K CCT are evaluated in the same process. Results show that the physiological response to music is stronger than that of the lighting stimulus. Music plays a major role in the sound‐light fusion environment, and the physiological perception under dual‐factor stimulation is stronger than that of single factor. Moreover, music and light interact with each other when they stimulate emotions at the same time. The superposition of two positively related factors can strengthen the effects on emotion. The studies may give suggestions to the designers when they design a lighting show with music or an immersive and interactive lighting project.
High‐Resolution Multi‐Isotope Imaging Mass Spectrometry (MIMS) Imaging Applications in Stem Cell Biology
Authors: McMahon G. , Lechene C.P. 
Published: November 2021

AbstractMulti‐isotope imaging mass spectrometry (MIMS) allows the measurement of turnover of molecules within intracellular compartments with a spatial resolution down to 30 nm. We use molecules enriched in stable isotopes administered to animals by diet or injection, or to cells through the culture medium. The stable isotopes used are, in general, 15N, 13C, 18O, and 2H. For stem cell studies, we essentially use 15N‐thymidine, 13C‐thymidine, and 81Br from BrdU. This protocol describes the practical use of MIMS with specific reference to applications in stem cell research. This includes choice and administration of stable isotope label(s), sample preparation, best practice for high‐resolution imaging, secondary ion mass spectrometry using the Cameca NanoSIMS 50L, and methods for robust statistical analysis of label incorporation in regions of interest (ROI). © 2021 The Authors. Current Protocols published by Wiley Periodicals LLC.Basic Protocol 1: Stable isotope labeling of DNA in cultured cellsBasic Protocol 2: Stable isotope labeling of DNA in animalsBasic Protocol 3: Preparation of Si chips, the general sample support for NanoSIMS analysisBasic Protocol 4: Stable isotope analysis of DNA replication in single nuclei in a population of cells with NanoSIMSBasic Protocol 5: Data reduction and processing