bluuebunny/crossref_metadata_2025_split huggingface dataset:
Children and young people’s contributions to public involvement and engagement activities in health-related research: A scoping review
Authors: Rouncefield-Swales Alison , Harris Jane , Carter Bernie , Bray Lucy , Bewley Toni , Martin Rachael 
Published: June 2021

BackgroundThere has been an increasing interest in how children and young people can be involved in patient and public involvement and engagement (PPIE) in health research. However, relatively little robust evidence exists about which children and young people are reported as being involved or excluded from PPIE; the methods reported as being used to involve them in PPIE; and the reasons presented for their involvement in PPIE and what happens as a result. We performed a scoping review to identify, synthesise and present what is known from the literature about patient and public involvement and engagement activities with children and young people in health related research.MethodsRelevant studies were identified by searches in Scopus, Medline, CINAHL, Cochrane and PsychInfo databases, and hand checking of reference lists and grey literature. An adapted version of the Guidance for Reporting Involvement of Patients and the Public (GRIPP2) was used as a framework to collate the data. Two reviewers independently screened articles and decisions were consensually made.Main findingsA total of 9805 references were identified (after duplicates were removed) through the literature search, of which 233 full-text articles were assessed for eligibility. Forty studies published between 2000 and 2019 were included in the review. The review reveals ambiguities in the quality of reporting of PPIE with children with clear reporting on demographics and health conditions. The review found that children and young people were commonly involved in multiple stages of research but there was also significant variation in the level at which children and young people were involved in PPIE. Evaluation of the impact of children and young people’s involvement in PPIE was limited.ConclusionsConsultation, engagement and participation can all offer children and young people worthwhile ways of contributing to research with the level, purpose and impact of involvement determined by the children and young people themselves. However, careful decisions need to be made to ensure that it is suited to the context, setting and focus so that the desired PPIE impacts are achieved. Improvements should be made to the evaluation and reporting of PPIE in research. This will help researchers and funders to better understand the benefits, challenges and impact of PPIE with children and young people on health research.
Is SF-12 a valid and reliable measurement of health-related quality of life among adults with Marfan syndrome? A confirmatory study
Authors: Udugampolage Nathasha , Caruso Rosario , Panetta Mariangela , Callus Edward , Dellafiore Federica , Magon Arianna , Marelli Susan , Pini Alessandro 
Published: June 2021

Introduction
The structural validity and reliability of the Short-Form Health Survey 12 (SF-12) has not yet been tested in adults with the Marfan syndrome (MFS). This gap could undermine an evidence-grounded practice and research, especially considering that the need to assess health-related quality of life in patients with MFS has increased due to the improved life expectancy of these patients and the need to identify their determinants of quality of life. For this reason, this study aimed to confirm the dimensionality (structural validity) of the SF-12, its concurrent validity, and its reliability (internal consistency).

Methods
We performed a cross-sectional study in a convenience sample of 111 Italian adults with MFS, collecting anamnestic and socio-demographic information, the SF-12, and short-form Health Survey 36 (SF-36). A confirmatory factor analysis was performed to verify whether the items of SF-12 related to physical restrictions, physical functioning, and bodily pain were retained by the physical summary component of the SF-12. The items referred to the role limitations due to emotional issues, social functioning, and mental health were retained by the mental summary component (MCS12). SF-36 was used to assess the concurrent validity of SF-12, hypothesizing positive correlations among the equivalent summary scores.

Results
The two-factor structural solution resulted in fitting the sample statistics adequately. The internal consistency was adequate for the two factors. Furthermore, the physical and mental summary scores of the SF-36 were positively correlated with their equivalent summary scores derived from the SF-12.

Conclusions
This study confirmed the factor structure of the SF-12. Therefore, the use of SF-12 in clinical practice and research for assessing the health-related quality of life among adults with MFS is evidence-grounded. Future research is recommended to determine whether the SF-12 shows measurement invariance in different national contexts and determine eventual demographic variation in the SF-12 scores among patients with MFS.
Speak English, Don’t Speak Vernacular. Language Culture and Practice, and Policy Implications in Schools
Authors: Kwao Alex , Torto Gertrude , Ackah-Jnr F. R. , John Appiah 
Published: June 2021

Compulsory adoption of language culture appears to heighten controversy and tension in schools. This phenomenon seems like a ‘dilemma’ judging from the way of policy and practice in schools. Language culture at the foundation stages seems to be strictly monolingual in some schools contrary to the dynamics of the education curriculum. This indeed seems to be a cultural idiosyncrasy that underpins cultural practices in some schools. Ghana Education Service recommends the speaking of English as medium of instruction at the early stages in schools, and so, English as official language is largely used at the foundation level. This investigation is looking at how a holistic approach could create a greater impart rather than applying a ’restrictionist’ theory in a school. This adherence calls for inquiry into ‘Speak English don’t speak vernacular in the school.’ The study employs a qualitative case study for the textual analysis. Two language teachers from ‘Kikako’ M.A. primary school in the Central region of Ghana were selected for the study. In-depth interview was the main instrument used. Analysis of data was by thematic sequencing using discursive, narrative and interpretive paradigms. The realisation of the study was that, the use of English only in schools was a controversial practice. Claims were that the use of vernacular also provided emergent and integrated literacy, which enhanced communication networking in the classrooms and school activities. It is absolutely useful to adopt English and vernacular in the school curriculum.
Remote teaching & digital platform during pandemic Teacher education and teacher competence effects among teachers & principles in Malaysia
Authors: RAMANLINGAM SHANTI 
Published: June 2021

The purpose of this research is analyzing the opportunities and challenges of emergency remote teaching based on experiences of the COVID-19 emergency among teachers and principals of Malaysian schools. This study explores the perceptions of school teachers of online learning in a program developed in Malaysian school called School from Home during the COVID-19 Pandemic. A qualitative research method was undertaken in two steps.

In the first step, a thematic analysis a qualitative method was used based on a two-step process. The first step consisted a Qualitative study which involved 4 school principals from Grade A and Grade B schools which is selected from four state which is Selangor, Johor, Kedah and Kelantan. In the second step (a Malaysian case study), The results from the interview discussion represented the basis for the second step, in which starting from the main issues that emerged from the online discussion among researches, professors and also Higher Education Offices from Ministry of Education and State Education Officers. The analysis reveals several technological, pedagogical and social challenges. The technological challenges are mainly related to the unreliability of Internet connections and many students’ lack of necessary electronic devices. (Chandler. D, 2017)

The pedagogical challenges are principally associated with teachers’ and learners’ lack of digital skills, the lack of structured content versus the abundance of online resources, learners’ lack of interactivity and motivation and teachers’ lack of social and cognitive presence (the ability to construct meaning through sustained communication within a community of inquiry) (Gordon, 2020) The social challenges are mainly related to the lack of human interaction between teachers and students as well as among the latter, the lack of physical spaces at home to receive lessons and the lack of support of parents who are frequently working remotely in the same spaces. Based on the lessons learned from this worldwide emergency, challenges and proposals for action to face these same challenges, which should be and sometimes have been implemented, are provided.
A Design of an Integrated Cloud-based Intrusion Detection System with Third Party Cloud Service
Authors: Elmasry Wisam , Akbulut Akhan , Zaim Abdul Halim 
Published: June 2021

AbstractAlthough cloud computing is considered the most widespread technology nowadays, it still suffers from many challenges, especially related to its security. Due to the open and distributed nature of the cloud environment, this makes the cloud itself vulnerable to various attacks. In this paper, the design of a novel integrated Cloud-based Intrusion Detection System (CIDS) is proposed to immunise the cloud against any possible attacks. The proposed CIDS consists of five main modules to do the following actions: monitoring the network, capturing the traffic flows, extracting features, analyzing the flows, detecting intrusions, taking a reaction, and logging all activities. Furthermore an enhanced bagging ensemble system of three deep learning models is utilized to predict intrusions effectively. Moreover, a third-party Cloud-based Intrusion Detection System Service (CIDSS) is also exploited to control the proposed CIDS and provide the reporting service. Finally, it has been shown that the proposed approach overcomes all problems associated with attacks on the cloud raised in the literature.
The effect of water-based rhythmic exercise training on glucose homeostasis and thyroid hormones in postmenopausal women with metabolic syndrome
Authors: Berahman Hanieh , Elmieh Alireza , Fadaei chafy Mohammad Reza 
Published: June 2021

Abstract

Objectives
The present study aimed to explore the effect of water-based rhythmic exercise training on fasting blood sugar (FBS), homeostatic model assessment (HOMA), insulin, thyroid stimulating hormone (TSH), and T4 in postmenopausal women with metabolic syndrome.

Methods
In this clinical trial, 31 postmenopausal woman with metabolic syndrome aged 69.16 ± 2.02 years were randomly assigned to an experimental (n=16) and a control group (n=15). The training program was composed of 12 weeks of water-based rhythmic exercise training performed intermittently for 60 min three times a week. Before and after training, blood was analyzed for glucose homeostasis, T4, and TSH. Data were subjected to analysis by paired t-test and covariance analysis at the p<0.05 level.

Results
The exercise training intervention reduced the FBS and insulin significantly (p=0.000). The growth hormone (GH) index was increased significantly only in the experimental group (p=0.037) whereas no significant variations occurred in the insulin-like growth factor-1 (p=0.712). It was also found that TSH and T4 change in the experimental group as compared to the pre-test.

Conclusions
Water-based rhythmic exercise training may improve blood glucose homeostasis, TSH, and T4.
Battery discharging model on fractal time sets
Authors: Ali Karmina Kamal , Golmankhaneh Alireza Khalili , Yilmazer Resat 
Published: June 2021

AbstractThis article is devoted to propose and investigate the fractal battery discharging model, which is one of the well-known models with a memory effect. It is presented as to how non-locality affects the behavior of solutions and how the current state of the system is affected by its past. Firstly, we present a local fractal solution. Then we solve the non-local fractal differential equation and examine the memory effect that includes the Mittag-Leffler function with one parameter. For that aim, the local fractal and non-local fractal Laplace transforms are used to achieve fractional solutions. In addition, the simulation analysis is performed by comparing the underlying fractal derivatives to the classical ones in order to understand the significance of the results. The effects of the fractal parameter and the fractional parameter are discussed in the conclusion section.
Investigating Indonesian EFL learners’ knowledge and use of English causative constructions
Authors: Wijaya David , Winstin Evelyn 
Published: June 2021

Abstract
This paper explored Indonesian EFL learners’ explicit knowledge, processing, and use of English periphrastic causative constructions make, have, and get. 20 English L1 speakers and 20 Indonesian intermediate level EFL learners majoring in English Language Education at an Indonesian university took part in this study. Data were collected through a cloze task, a sentence completion task, an interpretation task, and a set of open-ended questions asking learners to provide descriptions about their knowledge of the constructions. Results showed that learners did not always use the first noun strategy to identify the agent in a passive causative construction. Also, their suppliances of the causative verbs in most items did not significantly differ from L1 speakers. However, the syntactic patterns were mostly non-target-like. They demonstrated insufficient explicit knowledge that could enable them to verbalize the formal and functional aspects underlying the constructions. Pedagogical implications along with suggestions to improve instruction are discussed.
Adult males in maternity colonies of Daubenton’s bat, Myotis daubentonii: what are they?
Authors: Ružinská Romana , Kaňuch Peter 
Published: June 2021

Abstract
During summer, females of temperate zone bats form maternity colonies consisting almost exclusively of mothers and their offspring. However, in some species the proportion of males in nurseries is relatively high. We explored the presence of these males in Daubenton’s bat, with respect to their age and relatedness to the local maternity colony. Using automatic PIT-tag readers, we recorded individual swarming activity at roosts used for day roosting and discovered that most of the males were yearlings that returned to their nursery roost after hibernation. The elevated occurrence of yearling males in spring could be explained by late mating attempts or toleration in the territory of adults.
The crystal structure of tetrakis(1-isopropyl-1H-imidazolium) octamolybdate, C24H44Mo8N8O26
Authors: Yang Bingchuan , Lv Xueyan , Liu Rutao 
Published: June 2021

Abstract
C24H44Mo8N8O26, monoclinic, P21/n (no. 14), a = 10.3214(11) Å, b = 21.810(2) Å, c = 10.9371(11) Å, V = 2340.4(4) Å3, Z = 2, R

gt
(F) = 0.0423, wR

ref
(F
2) = 0.0893, T = 298(2) K.
Reactions of ozone and intermediate products of its decomposition with actinides, lanthanides and transition metals in aqueous solutions
Authors: Ershov Boris G. , Shilov Bladimir P. 
Published: June 2021

Abstract
The properties and stability of ozone in aqueous solutions of various compositions in the рН range of 0–14 were considered. The effect of anions and cations, which are involved in the redox reactions of actinides, on the stability of ozone and its reactivity has been studied. The reactions of О3 with ions of d- and f-elements were analyzed. Depending on the solution composition and рН value, the reaction can occur directly with the O3 molecule (direct mechanism) and/or with short-lived ion-radical products (•OH,

HO
2
•

/

O
2

−
•

${\text{HO}}_{2}^{{\bullet}}/{\text{O}}_{2}^{-{\bullet}}$

, H2O2/

HO
2
−

${\text{HO}}_{2}^{-}$

,

O
3

−
•

${\text{O}}_{3}^{-{\bullet}}$

) formed upon ozone decomposition in water (indirect mechanism). Ions with inert coordination sphere react with О3 in the outer-sphere fashion with electron transfer. Polyvalent ions with labile coordination spheres are oxidized in acidic medium via О atom transfer, possibly, with intermediate peroxy addition (H2O2, HNO4, H2SO5, etc.). In alkaline medium, О3 is converted to the

O
3

−
•

${\text{O}}_{3}^{-{\bullet}}$

radical ion, which is the key oxidant for actinides. The results of studies and the mechanisms of reactions of ozone and its intermediates decomposition products with U, Np, Pu, and Am in various oxidation states and with some transition metals (Fe, Mn, Ag, Co, etc.) in aqueous solutions are presented and discussed.
Air pollution increases the risk of pulmonary embolism: a meta-analysis
Authors: Miao Huangtai , Li Xiaoying , Wang Xiao , Nie Shaoping 
Published: June 2021

Abstract

Objectives
Air pollution can lead to many cardiovascular and respiratory diseases, but the impact of air pollution on pulmonary embolism is still uncertain. We conducted a meta-analysis to assess the relationship between air pollution and pulmonary embolism.

Content
We searched PubMed, EMBASE, Web of Science, and the Cochran Library for citations on air pollutants (carbon monoxide, sulfur dioxide, nitrogen dioxide, ozone and particulate matter) and pulmonary embolism. A total of nine citations met the inclusion criteria. There is no evidence of bias. CO, SO2, PM10 and PM2.5 had no significant effect on the occurrence of pulmonary embolism. NO2 and O3 can increase the risk of pulmonary embolism to a small extent.

Summary
This meta-analysis suggests that some air pollutants are associated with an increased risk of pulmonary embolism.

Outlook
Reducing air pollution and improving air quality can effectively reduce the risk of pulmonary embolism.
NO, CO and H2S based pharmaceuticals in the mission of vision (eye health): a comprehensive review
Authors: Mir Jan Mohammad , Maurya Ram Charitra , Khan Mohd Washid 
Published: June 2021

AbstractA set of well defined signaling molecules responsible for normal functioning of human physiology including nitric oxide along with carbon monoxide and hydrogen sulphide are referred as “gasotransmitters”. Due to their involvement in almost every system of a human body, the care of highly sensitive organs using these molecules as drugs represents highly fascinating area of research. In connection with these interesting aspects, the applied aspects of these gaseous molecules in maintaining healthy eye and vision have been targeted in this review. Several examples of eye-droppers including NORMs like latanoprost and nipradiol, CORMs like CORM-3 and CORM-A1, and Hydrogen sulfide releasing system like GYY4137 have been discussed in this context. Therefore the relation of these trio-gasotransmitters with the ophthalmic homeostasis on one hand, and de-infecting role on the other hand has been mainly highlighted. Some molecular systems capable of mimicking gasotransmitter action have also been introduced in connection with the titled theme.
Detection of circulating prostate cancer cells via prostate specific membrane antigen by chronoimpedimetric aptasensor
Authors: Uygun Zihni Onur , Girgin Sağin Ferhan 
Published: June 2021

Abstract

Objectives
Sensitive and accurate techniques for early detection of prostate cancer, which has a good chance for successful treatment if detected early, are of utmost value. Our aim is to develop a sensitive chronoimpedimetric biosensor for detection of circulating prostatic tumor cells (CTCs) with an aptamer selective for prostate specific membrane antigen (PSMA).

Methods
Thiolated PSMA-specific aptamer was immobilized on the gold nanoparticle modified carbon screen-printed electrodes. After characterization with cyclic voltammetry and electrochemical impedance spectrometry, scanning electron microscopy and atomic force microscopy studies were conducted to confirm the modifications. LNCaP cells (androgen-sensitive human prostate adenocarcinoma cells), were then added to the serum samples and chronoimpedimetric detection of CTCs in samples were performed.

Results
Our study showed one cell detection capability in real serum samples with a linear range from 1 to 40 cells/mL. The incubation time was 130 s. LOD was found to be 0.62 cells/mL and relative standard deviations were lower than 2% RSD. Reproducibility tests indicated a regression coefficient as R2 = 0.9963 ± 0.0178.

Conclusions
This new biosensor enables rapid, accurate, precise, reproducible and highly sensitive detection of PSMA on CTCs in prostate cancer and paves the way to new diagnostic applications and research-based studies.
Adiabatic compressibility of biphasic salt melts
Authors: Stepanov Victor P. 
Published: June 2021

Abstract
The adiabatic compressibility along the two-phase saturation line was calculated for nine molten immiscible mixtures, namely, LiF + KBr, LiF + CsCl, LiF + RbBr, LiF + KI, LiF + CsBr, LiF + RbI, LiF + CsI, LiCl + AgBr, and NaCl + AgI, using experimental data on the sound velocity and density. It is shown that the ratio of compressibility of the equilibrium phases depends significantly on the sizes of the mixed ions. The dependence of the changes in compressibility in the distance and in the vicinity of the critical mixing point on the characteristics of the chemical bond between the ions is discussed.
A synergy interaction of artocarpin and tetracycline against Pseudomonas aeruginosa and its mechanism of action on membrane permeability
Authors: Septama Abdi Wira , Rahmi Eldiza Puji , Antika Lucia Dwi , Dewi Rizna Triana , Jaisi Amit 
Published: June 2021

Abstract
The emergence of antibacterial resistance has significantly increased. Pseudomonas aeruginosa is associated with nosocomial infection and difficult to control. Artocarpin, a flavonoid from Artocarpus heterophyllus Lam. exhibits several pharmacological properties including antibacterial. The study was performed to evaluate interaction between artocarpin and antibiotics including tetracycline against P. aeruginosa. Its mechanism of action on membrane permeability was also investigated. Broth microdilution was conducted for the susceptibility assay. The interaction of artocarpin and antibiotics was evaluated using checkerboard method, the effect on alteration of membrane cell was investigated using bacteriolysis and the released of 260 nm materials. Artocarpin showed moderate to weak activity against the Gram-negative bacteria including P. aeruginosa with MIC values in the range of 31.25–250 μg/mL. A synergistic effect against P. aeruginosa was produced by the combination of artocarpin (31.25 μg/mL) and tetracycline (1.95 μg/mL) with FICI of 0.37. The time-killing assay showed that artocarpin enhance the antibacterial activity of tetracycline against P. aeruginosa by completely inhibiting the bacterial growth. Additionally, the mixture of artocarpin (31.25 μg/mL) and tetracycline (1.95 μg/mL) disrupted membrane permeability and lead to cell death. These results proposed that the combination of artocarpin and tetracycline may be used to overcome P. aeruginosa infection.