bluuebunny/crossref_metadata_2025_split huggingface dataset:
Charge Manipulation Based Selective Functionalization of 3D Printed Structures for Functional Devices
Authors: Chen Yang , Xiao Ting , Hu Minghui , Wang Nan , Pan Likun , Ling Xiaofeng , Gao Yang 
Published: December 2021

AbstractAs a rapid prototyping technology, digital light processing (DLP)‐based 3D printing has prospect in electronics for its excellent molding speed and accuracy. Although complex and precise models can be obtained by the DLP‐based 3D printing, the functionalization of the printed models is still a challenge. Herein, a cost‐effective, efficient, and scalable approach based on the electrostatic interaction for the selective deposition of multiwalled carbon nanotubes (MWCNTs) on structures printed by DLP technique is reported. The structures are fabricated by alternatively DLP 3D printing of neutrally and positively charged resins, with positively charged resin for attracting MWCNTs with negative charges. The positive and negative charges come from the cationic groups incorporated into the polymer matrix and the anionic dispersant on the MWCNTs, respectively. By controlling the pH and concentration of the functional material dispersion, as well as the deposition time, the characteristics of the deposited functional materials, including thickness and conductivity, can be modulated. In addition, an all‐solid‐state supercapacitor is developed by this method, delivering a capacitance of 30 µF cm−2 and a good electrochemical stability.
Synthesis of SCF3‐Substituted Sulfonium Ylides from Sulfonium Salts or α‐Bromoacetic Esters
Authors: Xiao Yushan , Jia Yimin , Huang Jinfeng , Li Xiangyu , Zhou Zhiwen , Zhang Jing , Jiang Mou , Zhou Xin , Jiang Zhong‐Xing , Yang Zhigang 
Published: December 2021

AbstractA metal‐free direct trifluoromethylthiolation of sulfonium ylides with an electrophilic trifluoromethylthiolating reagent has been established, in which sulfonium salt or α‐bromoacetic ester is employed as sulfonium ylide precursors. This trifluoromethylthiolation enables the straightforward construction of SCF3‐substituted sulfonium ylides from a wide range of substrates, including ketones, esters, and even PEGylated substrates. Moreover, the application of this approach in large‐scale preparation and the fluorescence and fluorine‐19 magnetic resonance imaging capabilities of the product are also explored.magnified image
Hydrogenation of Esters by Manganese Catalysts
Authors: Li Xiao‐Gen , Li Fu , Xu Yue , Xiao Li‐Jun , Xie Jian‐Hua , Zhou Qi‐Lin 
Published: December 2021

AbstractThe hydrogenation of esters catalyzed by a manganese complex of phosphine‐aminopyridine ligand was developed. Using this protocol, a variety of (hetero)aromatic and aliphatic carboxylates including biomass‐derived esters and lactones were hydrogenated to primary alcohols with 63–98% yields. The manganese catalyst was found to be active for the hydrogenation of methyl benzoate, providing benzyl alcohol with turnover numbers (TON) as high as 45,000. Investigation of catalyst intermediates indicated that the amido manganese complex was the active catalyst species for the reaction.magnified image
Hetero‐Lattice Intergrown and Robust MOF Membranes for Polyol Upgrading
Authors: Wang Yuecheng , Ban Yujie , Hu Ziyi , Zhao Yang , Zheng Mingyuan , Yang Weishen , Zhang Tao 
Published: December 2021

AbstractMetal–organic framework membranes are frequently used in gas separations, but rare in pervaporation for liquid chemical upgrading, especially for separating water from polyols, due to lack of highly compact and robust micro‐architecture. Here, we report hetero‐lattice intergrown membranes in which amino‐MIL‐101 (Cr) particles embedded into the micro‐gaps of MIL‐53 (Al) rod arrays after secondary growth. By means of high‐resolution TEM and two‐dimensional topologic simulation, the connection between these two distinct MOF lattices at the molecular‐level and their crystallographic geometry harmony is identified, which leads to a close‐knit structure at the crystal boundaries of membranes. Typically, the membrane shows a separation factor as high as 13 000 for a 90/10 ethanediol/water solution in pervaporation, yields polymer‐grade ethanediol, and saves ca. 32 % of energy consumption vs. vacuum distillation. It has a highly robust micro‐architecture, with great tolerance to high pressure, durability against ultrasonic therapy and long‐term separation stability over 600 h.
Copper‐Catalyzed Covalent Dimerization of Near‐Infrared Fluorescent Cyanine Dyes: Synergistic Enhancement of Photoacoustic Signals for Molecular Imaging of Tumors
Authors: Maji Dolonchampa , Oh Donghyeon , Gautam Krishna Sharmah , Zhou Mingzhou , Zhang Haini , Kao Jeff , Giblin Daryl , Smith Matthew , Lim Junha , Lee Seunghyun , Kang Youngnam , Kim Won Jong , Kim Chulhong , Achilefu Samuel 
Published: December 2021

AbstractInvited for this month's cover is the group of Prof. Samuel Achilefu at the Washington University School of Medicine and colleagues at the Pohang University of Science and Technology. The cover picture shows copper (the hammer) catalyzing the assembly of monomeric near‐infrared fluorescent dye molecules, cypate (yellow glow), into covalently‐linked dimeric molecules (merged red balls). More information can be found in the Communication at 10.1002/anse.202100045.
Preparation and properties of green UV‐curable itaconic acid cross‐linked modified waterborne polyurethane coating
Authors: Dong Xiangbin , Ren Jingyu , Duan Yanjie , Wu Dandan , Lin Lin , Shi Jichao , Jia Runping , Xu Xiaowei , He Xinyao 
Published: December 2021

AbstractWaterborne polyurethane (WPU) coating, as a kind of green product, can replace solvent polyurethane coating, but its application in the field of coating is limited since its defects such as slow curing efficiency, low strength, and water resistance. In this study, a trifunctional itaconic acid‐based crosslinking agent (IHA) was synthesized from itaconic acid and hydroxyethyl acrylate. A series of green UV‐curable WPU coatings were prepared by introducing IHA into WPU prepolymer in different proportions (2.5 ~ 10 wt.%). IHA posed as crosslinking agent in WPU, which can not only enhance strength, but also accelerate curing rate in WPU coatings. The results demonstrated that the gel content and hydrophobic angle of the modified WPU coating (WPU‐IHA) are increased by 25.6% and 34.8°, respectively, indicating a good water resistance. Most notably, due to the increase of crosslinking degree and the decrease of chain mobility, the UV‐curable WPU coating shows excellent mechanical properties with 21.9 MPa in tensile strength and a pencil hardness of 5H, which is substantially higher than that of pure WPU coatings. Therefore, the IHA shows great potential to substitute petroleum‐based crosslinking agents in the preparation of environmentally friendly UV‐curable WPU coatings with high strength and good surface scratch hardness.
Experiences of student and trainee autism researchers during the COVID‐19 pandemic
Authors: Kaku Sowmyashree Mayur , McVey Alana J. , Gerber Alan H. , Pretzsch Charlotte M. , Jones Desiree R. , Kodakkadan Fathima Muhsina , Lei Jiedi , Singer Lauren , Chitehwe Lucy , Poulsen Rebecca Elizabeth , Coffman Marika 
Published: December 2021

AbstractCircumstances surrounding the COVID‐19 pandemic have resulted in significant personal and professional adjustments. Students and trainees, including those in autism research, face unique challenges to accomplishing their training and career goals during this unprecedented time. In this commentary, we, as members of the International Society for Autism Research Student and Trainee Committee, describe our personal experiences, which may or may not align with those of other students and trainees. Our experiences have varied both in terms of the ease (or lack thereof) with which we adapted and the degree to which we were supported in the transition to online research and clinical practice. We faced and continue to adjust to uncertainties about future training and academic positions, for which opportunities have been in decline and have subsequently negatively impacted our mental health. Students and trainees' prospects have been particularly impacted compared to more established researchers and faculty. In addition to the challenges we have faced, however, there have also been unexpected benefits in our training during the pandemic, which we describe here. We have learned new coping strategies which, we believe, have served us well. The overarching goal of this commentary is to describe these experiences and strategies in the hope that they will benefit the autism research community moving forward. Here, we provide a set of recommendations for faculty, especially mentors, to support students and trainees as well as strategies for students and trainees to bolster their self‐advocacy, both of which we see as crucial for our future careers.Lay SummaryThe COVID‐19 pandemic has affected students and trainees, including those in autism research, in different ways. Here, we describe our personal experiences. These experiences include challenges. For example, it has been difficult to move from in‐person to online work. It has also been difficult to keep up with work and training goals. Moreover, working from home has made it hard to connect with our supervisors and mentors. As a result, many of us have felt unsure about how to make the best career choices. Working in clinical services and getting to know and support our patients online has also been challenging. Overall, the pandemic has made us feel more isolated and some of us have struggled to cope with that. On the other hand, our experiences have also included benefits. For example, by working online, we have been able to join meetings all over the world. Also, the pandemic has pushed us to learn new skills. Those include technical skills but also skills for well‐being. Next, we describe our experiences of returning to work. Finally, we give recommendations for trainees and supervisors on how to support each other and to build a strong community.
Investigation of the Anode‐Electrolyte Interface in a Magnesium Full‐Cell with Fluorinated Alkoxyborate‐Based Electrolyte
Authors: Roy Ananyo , Bhagavathi Parambath Vinayan , Diemant Thomas , Neusser Gregor , Kranz Christine , Behm R. Jürgen , Li Zhenyou , Zhao‐Karger Zhirong , Fichtner Maximilian 
Published: December 2021

AbstractMagnesium (Mg) anode‐electrolyte interaction is not trivial and investigation of the interfacial process can be helpful for the development of Mg batteries. In this work, we studied the Mg metal anode cycled in a chloride (Cl)‐free magnesium tetrakis (hexafluoroisopropyloxy) borate electrolyte using a full‐cell configuration with TiS2 model cathode. Electrochemical measurements and structural analysis of the cathode showed reversible de‐/magnesiation of TiS2 with some entrapment of irreversibly bound Mg2+. Electrochemical impedance spectroscopy (EIS) was applied to analyze the Mg‐electrolyte interaction in a three‐electrode system. The results showed a rapid increase in charge transfer resistance on the anode side with increasing resting time. In contrast, we observed a significant drop in the charge transfer impedance upon cycling along with the appearance of an additional semi‐circle, which suggested to the development of a solid interphase. X‐ray photoelectron spectroscopy (XPS) and Fourier transform infrared spectroscopy (FTIR) corroborated the EIS results and confirmed the solid interphase layer formation, in which MgF2 was identified as the primary species contributing to its formation. The current study provides fundamental insights into the interfacial phenomena between the metallic Mg anode and Cl‐free electrolyte by highlighting the role played by the formed interphase on the reversible Mg stripping and plating in a Mg full‐cell.
Cardiovascular‐specific PSEN1 deletion leads to abnormalities in calcium homeostasis
Authors: Song Xiao‐Wei , Zhao Feng , Yang Jing , Yuan Qing‐Ning , Zeng Zhen‐Yu , Shen Ming , Tang Ying , Cao Mi , Shen Ya‐Feng , Li Song‐Hua , Yang Yong‐Ji , Wu Hong , Zhao Xian‐Xian , Hu Shu‐Ting 
Published: December 2021

AbstractMutations of PSEN1 have been reported in dilated cardiomyopathy pedigrees. Understanding the effects and mechanisms of PSEN1 in cardiomyocytes might have important implications for treatment of heart diseases. Here, we showed that PSEN1 was downregulated in ischemia‐induced failing hearts. Functionally, cardiovascular specific PSEN1 deletion led to spontaneous death of the mice due to cardiomyopathy. At the age of 11 months, the ratio of the heart weight/body weight was slightly lower in the Sm22a‐PSEN1‐KO mice compared with that of the WT mice. Echocardiography showed that the percentage of ejection fraction and fractional shortening was significantly reduced in the Sm22a‐PSEN1‐KO group compared with the percent of these measures in the WT group, indicating that PSEN1‐KO resulted in heart failure. The abnormally regulated genes resulted from PSEN1‐KO were detected to be enriched in muscle development and dilated cardiomyopathy. Among them, several genes encode Ca2+ ion channels, promoting us to investigate the effects of PSEN1 KO on regulation of Ca2+ in isolated adult cardiomyocytes. Consistently, in isolated adult cardiomyocytes, PSEN1‐KO increased the concentration of cytosolic Ca2+ and reduced Ca2+ concentration inside the sarcoplasmic reticulum (SR) lumen at the resting stage. Additionally, SR Ca2+ was decreased in the failing hearts of WT mice, but with the lowest levels observed in the failing hearts of PSEN1 knockout mice. These results indicate that the process of Ca2+ release from SR into cytoplasm was affected by PSEN1 KO. Therefore, the abnormalities in Ca2+ homeostasis resulted from downregulation of PSEN1 in failing hearts might contribute to aging‐related cardiomyopathy, which might had important implications for the treatment of aging‐related heart diseases.
Emergence of Concentration Effects in the Variational Analysis of theN‐Clock Model
Authors: Cicalese Marco , Orlando Gianluca , Ruf Matthias 
Published: December 2021

AbstractWe investigate the relationship between theN‐clock model (also known as planar Potts model or‐model) and theXYmodel (at zero temperature) through a Γ‐convergence analysis of a suitable rescaling of the energy as both the number of particles andNdiverge. We prove the existence of rates of divergence ofNfor which the continuum limits of the two models differ. With the aid of Cartesian currents we show that the asymptotics of theN‐clock model in this regime features an energy that may concentrate on geometric objects of various dimensions. This energy prevails over the usual vortex‐vortex interaction energy. © 2022 The Authors.Communications on Pure and Applied Mathematicspublished by Wiley Periodicals LLC.
Sensitivity of tidal hydrodynamics to varying bathymetric configurations in a multi‐inlet rapidly eroding salt marsh system: A numerical study
Authors: Deb Mithun , Abdolali Ali , Kirby James T. , Shi Fengyan , Guiteras Susan , McDowell Conor 
Published: December 2021

AbstractWe describe the development of a high‐resolution, two‐dimensional hydrodynamic model for a multi‐inlet rapidly eroding tidal wetland on the western shore of Delaware Bay, using the finite‐volume, primitive equation community ocean model (FVCOM). Topo‐bathymetric surveys, together with water surface and current velocity measurements during calm and stormy conditions, have been conducted to support model validation. The tested model is then used to quantify the tide‐induced residual transport and asymmetry at major inlet entrances to determine the governing hydrodynamics. We chose a skewness method to calculate the tidal asymmetry and serve as a proxy for sediment transport estimates. The effects of the dredging of an artificial entrance channel and progressive channel deepening in shifting wetland hydrodynamics are shown by developing a scenario analysis. Model results show that the artificially dredged channel has altered the volume exchange at other inlet entrances and increased the net seaward export. The changes in the characteristic frequency of the frictional dissipation in the channel and the system's natural frequency are investigated using a simple ocean–inlet–bay analytical model. Subsequently, we have compared the channel friction scale to the inertia scale and observed that the new connection and gradual channel deepening reduce the overall frictional dominance. Ultimately, the study has shown how the short‐ and long‐term channel bathymetry changes, mainly the artificially dredged channel and progressive channel deepening, can affect the connected system's net circulation and trigger internal marsh erosion.
Female body mass index and the selection of a long‐acting reversible contraception for the first time
Authors: Frederico Giulia , Silva dos Santos Priscilla N. , Ferreira Jéssica M. , Bahamondes Luis , Fernandes Arlete 
Published: December 2021

AbstractObjectiveTo evaluate Brazilian women with different body mass index (BMI, calculated as weight in kilograms divided by the square of height in meters) values who were switching from a short‐acting reversible contraceptive (SARC) to a long‐acting reversible contraceptive (LARC) method in relationship to the reasons reported for switching and the LARC method chosen.MethodWe analyzed retrospective data from 1508 women aged 18–49 years who chose a LARC for the first time. The variables were sociodemographic, BMI, SARC in use, the reason given for switching, the chosen LARC (copper intrauterine device, levonorgestrel (52 mg) intrauterine system or ethyl norgestrel implant), and expectations of the LARC. We used χ2, Mann‐Whitney, and Kruskal‐Wallis tests to compare BMI groups. The significance level adopted was 5%.ResultsThe obesity group, 320 women (21.2%), reported weight gain (P < 0.000) and fear of pregnancy (P = 0.004) as the most frequent reasons for switching, whereas the normal weight group, 637 women (42.2%), reported more loss of libido (P < 0.000) and other personal complaints (P = 0.002). The IUD was chosen by 851 women (56.6%) and significantly by the largest number of obese women.ConclusionWomen in different BMI categories report different reasons for switching from SARC methods and elect different LARC methods for contraception.
Possible protective effects of CO Q10 against vincristine‐induced peripheral neuropathy: Targeting oxidative stress, inflammation, and sarmoptosis
Authors: Elshamy Amira M. , Salem Ola M. , Safa Mohamed A. E. , Barhoma Ramez A. E. , Eltabaa Eman F. , Shalaby Amany M. , Alabiad Mohamed A. , Arakeeb Heba M. , Mohamed Hoda A. 
Published: December 2021

AbstractVincristine is a chemotherapy drug that belongs to the vinca alkaloids group. It is used for treatment of hematologic malignancies and several solid tumors. Vincristine‐induced peripheral neuropathy is a major dose‐limiting side effect. Coenzyme Q10 (Co Q10), an essential component of the mitochondrial electron transport chain, participates in energy production. It is a powerful fat‐soluble antioxidant and also exerts anti‐inflammatory effects. Therefore, this study was aimed to focus on the mechanistic insights of vincristine‐induced peripheral neuropathy in addition to shedding the light on the modulatory effect of Co Q10. Twenty‐eight rats were randomly divided into four groups. Peripheral neuropathy was induced by intraperitoneal injection of vincristine (0.1 mg/kg body weight). Co Q10 was injected intraperitoneally (10 mg/kg body weight) for 24 days. Sciatic nerve MDA, TAC, GSH, 8‐OHdG, TNF‐α, IL‐1β, and NF‐κB levels were assessed. Gene expression of SARM1 and Nrf2 was also assessed. Serum neurofilament light chain was immunoassayed, in addition to the behavioral assessment. Co Q10 significantly improved oxidative stress and inflammatory biomarkers. It also decreased serum NFL levels. It enhanced Nrf2 and decreased SARM1 gene expression. Histopathological findings proved the biochemical and molecular findings. Our results support Co Q10 as a potential protective agent against vincristine‐induced peripheral neuropathy.
The combination of dapagliflozin and statins ameliorates renal injury through attenuating the activation of inflammasome‐mediated autophagy in insulin‐resistant rats
Authors: Thongnak Laongdao , Pengrattanachot Nattavadee , Promsan Sasivimon , Phengpol Nichakorn , Sutthasupha Prempree , Chatsudthipong Varanuj , Lungkaphin Anusorn 
Published: December 2021

AbstractLong‐term use of a high‐fat diet with high‐fructose (HFF) intake could promote insulin resistance and induce lipid accumulation leading to kidney injury possibly via impairment of the autophagy process and enhancement of the inflammasome pathway. We investigated whether dapagliflozin as a monotherapy or combined with atorvastatin could restore kidney autophagy impairment and reduce inflammasome activation associated with kidney injury induced by HFF consumption. Male Wistar rats were given an HFF for 16 weeks and then treated with dapagliflozin with or without atorvastatin for 4 weeks. Impaired glucose tolerance, dyslipidemia, renal lipid accumulation along with impaired renal autophagy and activated inflammasome pathway promoted renal injury were exhibited in HFF rats. Dapagliflozin with or without atorvastatin treatment could partially restore disrupted metabolic parameters and reduce kidney injury. In particular, the combination treatment group showed significant amelioration of inflammasome activation and autophagy impairment. In conclusion, the combination therapy of dapagliflozin and atorvastatin has a positive effect on renal injury associated with autophagy and inflammasome activation induced by HFF in insulin‐resistant rats. This study is the first report demonstrating the underlying mechanism associated with a combination treatment of dapagliflozin and atorvastatin on autophagy and inflammasome pathways in an insulin‐resistant condition. Therefore, dapagliflozin in combination with atorvastatin may be a further preventive or therapeutic strategy for chronic kidney disease in an insulin‐resistant or diabetic condition.