bluuebunny/crossref_metadata_2025_split huggingface dataset:
An improved capacitor voltage full feedforward control strategy for LCL‐type grid‐connected inverter based on control delay compensation
Authors: Yang Xingwu , Wu Guokuai , Meng Zhicheng , Wang Yani , Ji Liang , Xue Hua , Bian Xiaoyan 
Published: October 2021

AbstractFor the LCL‐type grid‐connected inverter, when the capacitor voltage feedforward is applied, the delay in the digital control system could change the phase characteristics of capacitor voltage feedback and affect the stability of the system. To solve the problem, a delay compensation method based on lead compensator is proposed in this paper, which can reduce the impacts of control delay on the capacitor voltage full feedforward control system. In this study, a lead compensator is introduced into the feedforward channel to compensate the phase lag, and the compensation function is designed to compensate for the phase margin but not change the system amplitude gain. The proposed strategy can keep the phase margin of the system above 25° when the grid impedance changes from 0 to 2.6 mH (0.1 p.u.), which enhances the robustness of the grid‐connected inverter under weak condition. The grid current distortion caused by grid background harmonics is greatly reduced and is kept within 4%. Moreover, the proposed strategy has fast dynamics while ensuring the system stability. Finally, the simulation and experimental results are presented to verify the effectiveness and robustness of the proposed control strategy.
The LSBmax algorithm for boosting resilience of electric grids post (N‐2) contingencies
Authors: Hussain Tanveer , Alam S M Shafiul , Hansen Timothy M. , Suryanarayanan Siddharth 
Published: October 2021

AbstractA computationally improved algorithm is presented to find the best transmission switching (TS) candidate for boosting resilience of electricity grids subject to (N‐2) contingencies. Here, resilience is computed as the reduction in load shed after the above‐mentioned (N‐) contingencies. TS is a planned line outage, and past research shows that changing the transmission system's topology changes the power flow and removes post contingency violations. Finding the best TS candidate in a computationally suitable time for effectively boosting resilience is a challenge. The best TS candidate is found using a novel heuristic method by decreasing the search space based on proximity to the bus with the maximum load shedding (LSB). The LSB algorithm is faster than existing algorithms in the literature; and, it is compatible with both the AC and DC optimal power flow formulations. To validate the authors' claims of speedup and accuracy, two metrics are used to analyze the results from the IEEE 39‐bus and 118‐bus systems. Finally, the inherent parallelism of the LSB algorithm is leveraged on a high‐performance computing platform and applied to the large‐scale Polish 2383‐bus test system to validate scalability in both size and speedup in computation time.
A 3.5 Mpc long radio relic in the galaxy cluster ClG 0217+70
Authors: Hoang D. N. , Zhang X. , Stuardi C. , Shimwell T. W. , Bonafede A. , Brüggen M. , Brunetti G. , Botteon A. , Cassano R. , de Gasperin F. , Di Gennaro G. , Hoeft M. , Intema H. , Rajpurohit K. , Röttgering H. J. A. , Simionescu A. , van Weeren R. J. 
Published: October 2021

Context. Megaparsec-scale radio sources in the form of halos and relics are often detected in dynamically disturbed galaxy clusters. Although they are associated with merger-induced turbulence and shocks, respectively, their formation is not fully understood.
Aims. We aim to identify the mechanisms responsible for particle acceleration and magnetic field amplification in the halo and relics of the galaxy cluster ClG 0217+70.
Methods. We observed ClG 0217+70 with LOFAR at 141 MHz and with VLA at 1.5 GHz, and we combined these observations with VLA 1.4 GHz archival data to study the morphological and spectral properties of the diffuse sources. We added Chandra archival data to examine the thermal and non-thermal properties of the halo.
Results. Our LOFAR and VLA data confirm the presence of a giant radio halo in the cluster centre and multiple relics in the outskirts. The radio and X-ray emission from the halo are correlated, implying a tight relation between the thermal and non-thermal components. The diffuse radio structure in the south-east, with a projected size of 3.5 Mpc, is the most extended radio relic detected to date. The spectral index across the relic width steepens towards the cluster centre, suggesting electron ageing in the post-shock regions. The shock Mach numbers for the relics derived from the spectral index map range between 2.0 and 3.2. However, the integrated spectral indices lead to increasingly high Mach numbers for the relics farther from the cluster centre. This discrepancy could be because the relation between injection and integrated spectra does not hold for distant shocks, suggesting that the cooling time for the radio-emitting electrons is longer than the crossing time of the shocks. The variations in the surface brightness of the relics and the low Mach numbers imply that the radio-emitting electrons are re-accelerated from fossil plasma that could originate in active galactic nuclei.
A Sustainability Index tool for measuring the Environmental performance of a metropolitan city
Authors: Dhawan Akshay , Gupta Nakul , Kuldeep K. Saxena , Goyal Rajesh 
Published: October 2021

This paper targets estimating and evaluating the Indian Cities on the natural execution rules across an expansive scope of classifications and supporting markers. Metropolitan urban areas have different Environmental issues like never-ending suburbia, Deprive of green and characteristic gaps, insufficient H2O supply, sewage water, solid refuse, contamination of air and soil. To combat such issues, the urban communities are being modified by presenting shrewd feasible procedures.
There are various advantages straightforwardly joined to the manageability estimating apparatus such as to limit the natural impression of city, oblige populace development, and protect personal satisfaction of metropolitan occupants today and in future. It additionally assists financial backers with settling on a decision of their area, helps urban communities by being a directing soul to enroll different qualities and shortcomings of the urban communities and in this way helping them in progress by chipping away at their shortcomings and in characterizing and arranging their objectives and to plan pointed toward supporting their involved position and to foster arrangement for what’s to come.
Metformin – bei Typ-2-Diabetes das Mittel der ersten Wahl?!
Authors: Gröber Uwe 
Published: October 2021

ZusammenfassungDiabetes mellitus und Prädiabetes haben in Deutschland eine sehr hohe Prävalenz. Obwohl körperliche Aktivität und nutritive Intervention sich als wirksam erwiesen haben, bleibt das blutzuckersenkende Metformin das Mittel der ersten Wahl. Das Medikament interferiert mit Mikronährstoffen wie B-Vitaminen, Vitamin D und Magnesium und kann den bei Typ-2-Diabetiker*innen oft bestehenden Nährstoffmangel noch verstärken. Daraus resultieren u. a. negative Folgen für Energiestoffwechsel, Immunsystem, Inflammation und Insulinresistenz sowie ein Anstieg des gefäßschädigenden Homocysteins. Halbjährliche Kontrollen der Homocystein-, Methylmalonsäure- und Vitamin-D-Spiegel sind bei Typ-2-Diabetes ratsam. Inbs. bei Metformintherapie bzw. Polymedikation sollten die Mikronährstoffmängel durch tägliche Supplementierung ausgeglichen werden.
Evaluation of Protective Effects of Curcumin and Nanocurcumin on
Aluminium Phosphide‑Induced Subacute Lung Injury in Rats: Modulation of
Oxidative Stress through SIRT1/FOXO3 Signalling Pathway
Authors: Mahlooji Mohammad Ali , Heshmati Ali , Kheiripour Nejat , Ghasemi Hassan , Asl Sara Soleimani , Solgi Ghasem , Ranjbar Akram , Hosseini Asieh 
Published: October 2021

Abstract
Objective Aluminum phosphide (AlP) is widely used to protect stored food
products and grains from pests and rodents. The availability of AlP, especially
in Asian countries it has become a desirable factor to commit suicide. The
phosphine produced from ALP is a very reactive radical and a respiratory
inhibitor that causes oxidative damage. There is no dedicated antidote or
effective drug to manage AlP-induced lung toxicity. The present study aims to
evaluate and compare the protective effects of curcumin and nanocurcumin on
ALP‑induced subacute lung injury and determine the underlying mechanism.
Methods Rats were exposed to AlP (2 mg/kg/day,
orally)+curcumin or nanocurcumin (100 mg/kg/day,
orally) for 7 days. Then rats were anesthetized and lung tissues were collected.
Oxidative stress biomarkers, genes expression of antioxidant enzymes,
participated genes in the SIRT1/FOXO3 pathway, and lung histopathology
were assessed by biochemical and ELISA methods, Real-Time PCR analysis, and
H&E staining.
Results Curcumin and nanocurcumin produced a remarkable improvement in
AlP-induced lung damage through reduction of MDA, induction of antioxidant
capacity (TAC, TTG) and antioxidant enzymes (CAT, GPx), modulation of
histopathological changes, and up-regulation of genes expression of SIRT1,
FOXO3, FOXO1 in lung tissue.
Conclusion Nanocurcumin had a significantly more protective effect than
curcumin to prevent AlP-induced lung injury via inhibition of oxidative stress.
Nanocurcumin could be considered a suitable therapeutic choice for AlP
poisoning.
Design and Baseline Data for a Prospective Observational Study of Rivaroxaban in Patients with Venous Thromboembolism in Japan (XASSENT)
Authors: Fukuda Ikuo , Hirayama Atsushi , Kawasugi Kazuo , Kobayashi Takao , Maeda Hideaki , Nakamura Mashio , Nakanishi Norifumi , Yamada Norikazu , Tajima Tsubasa , Iwashiro Sanghun , Okayama Yutaka , Sunaya Toshiyuki , Hirano Kazufumi , Hayasaki Takanori 
Published: October 2021

Abstract
Background The efficacy and safety of rivaroxaban have been demonstrated in phase 3 trials of patients with venous thromboembolism (VTE; pulmonary embolism [PE] and deep vein thrombosis [DVT]). Data regarding rivaroxaban treatment of VTE in routine Japanese clinical practice remain limited.
Objectives XASSENT will evaluate rivaroxaban treatment of VTE in real-world Japanese clinical practice. We report the study design and baseline patient characteristics.
Methods XASSENT (NCT02558465) is an open-label, prospective observational, post-marketing surveillance cohort study in patients receiving rivaroxaban treatment for VTE. Enrolment took place between November 2015 and March 2018. XASSENT will follow patients for up to 2 years. Primary outcome variables: major bleeding and symptomatic recurrent VTE. Statistical analyses are exploratory and descriptive.
Results Baseline patient characteristics at June 2020 (n = 2,299) are presented (58.2% female; mean age 66.7 years; mean weight 60.9 kg). The population encompasses patients with wide-ranging characteristics including older age, low weight, and renal dysfunction. Most participants (67.6%) had a history of VTE risk factors at baseline. Half of the population (50.4%) had DVT only; 41.4% had DVT with PE; 8.2% had PE only. Overall, 68.4% were inpatients and 77.1% had symptomatic VTE. Rivaroxaban was prescribed for initial treatment in 84.6% of patients and maintenance treatment in 15.4%. Most were prescribed the approved dose of rivaroxaban for initial (30 mg daily; 84.4%) or maintenance (15 mg daily; 81.9%) treatment of VTE in Japan. The most common reason for selecting non-recommended dose was ‘elderly’.
Conclusions Results from XASSENT will complement phase 3 trial data and inform clinical practice.
Neuropalliative Care in the Inpatient Setting
Authors: Goss Adeline L. , Creutzfeldt Claire J. 
Published: October 2021

AbstractThe palliative care needs of inpatients with neurologic illness are varied, depending on diagnosis, acuity of illness, available treatment options, prognosis, and goals of care. Inpatient neurologists ought to be proficient at providing primary palliative care and effective at determining when palliative care consultants are needed. In the acute setting, palliative care should be integrated with lifesaving treatments using a framework of determining goals of care, thoughtfully prognosticating, and engaging in shared decision-making. This framework remains important when aggressive treatments are not desired or not available, or when patients are admitted to the hospital for conditions related to advanced stages of chronic neurologic disease. Because prognostic uncertainty characterizes much of neurology, inpatient neurologists must develop communication strategies that account for uncertainty while supporting shared decision-making and allowing patients and families to preserve hope. In this article, we illustrate the approach to palliative care in inpatient neurology.
Neuroprognostication after Cardiac Arrest: Who Recovers? Who Progresses to Brain Death?
Authors: Carroll Elizabeth , Lewis Ariane 
Published: October 2021

AbstractApproximately 15% of deaths in developed nations are due to sudden cardiac arrest, making it the most common cause of death worldwide. Though high-quality cardiopulmonary resuscitation has improved overall survival rates, the majority of survivors remain comatose after return of spontaneous circulation secondary to hypoxic ischemic injury. Since the advent of targeted temperature management, neurologic recovery has improved substantially, but the majority of patients are left with neurologic deficits ranging from minor cognitive impairment to persistent coma. Of those who survive cardiac arrest, but die during their hospitalization, some progress to brain death and others die after withdrawal of life-sustaining treatment due to anticipated poor neurologic prognosis. Here, we discuss considerations neurologists must make when asked, “Given their recent cardiac arrest, how much neurologic improvement do we expect for this patient?”
Radiation Lobectomy: An Overview of Concept and Applications, Technical Considerations, Outcomes
Authors: Entezari Pouya , Gabr Ahmed , Kennedy Kristie , Salem Riad , Lewandowski Robert J. 
Published: October 2021

AbstractSurgical resection has long been considered curative for patients with early-stage hepatocellular carcinoma (HCC). However, inadequate future liver remnant (FLR) renders many patients not amenable to surgery. Recently, lobar administration of yttrium-90 (Y90) radioembolization has been utilized to induce FLR hypertrophy while providing disease control, eventually facilitating resection in patients with hepatic malignancy. This has been termed “radiation lobectomy (RL).” The concept is evolving, with modified approaches combining RL and high-dose curative-intent radioembolization (radiation segmentectomy) to achieve tumor ablation. This article provides an overview of the concept and applications of RL, including technical considerations and outcomes in patients with hepatic malignancies.
Extrahepatic Applications of Yttrium-90 Radioembolization
Authors: Murali Nikitha , Mouli Samdeep K. , Riaz Ahsun , Lewandowski Robert J. , Salem Riad 
Published: October 2021

AbstractWhile initially described and now accepted as treatment for primary and secondary malignancies in the liver, radioembolization therapy has expanded to include treatment for other disease pathologies and other organ systems. Advantages and limitations for these treatments exist and must be compared against more traditional treatments for these processes. This article provides an overview of the current applications for radioembolization outside of the liver, for both malignant and nonmalignant disease.
Pancreatoblastoma with Portal Venous Invasion: A Case Series
Authors: Abbey Pooja , Anand Rama 
Published: October 2021

AbstractWe describe the sonography and computed tomography (CT) findings in three children with pancreatoblastoma and highlight the tendency of these tumors to invade the splenoportal axis. All three of our cases showed tumor thrombus within the portal vein which is a helpful diagnostic feature on imaging studies.
COVID-19–Associated Bone Marrow Necrosis—A Case Report
Authors: Ghosh Soumyadeep , Gupta Santosh S. , Mehta Nirad , Khodaiji Shanaz 
Published: October 2021

AbstractWe report, herein, a rare case of vertebral bone marrow necrosis in a patient at 1-month post–novel coronavirus disease 2019 (COVID-19) pneumonia complicated with disseminated intravascular coagulation (DIC). The commonly observed radiological features on the imaging modalities like computed tomography (CT), magnetic resonance imaging (MRI), and 18-F fluorodeoxyglucose positron emission tomography (FDG PET) have been discussed here followed by a brief discussion on the role of in-phase and opposed-phase imaging in differentiating the disease from malignant infiltrative pathologies. Histopathological findings on bone marrow smear that confirm the diagnosis have also been illustrated.
Sinus of Valsalva Rupture or VSD Shunt: Mystery Solved by Cardiac CT
Authors: Vora Keyur , Surana Uday , Ranjan Alok 
Published: October 2021

AbstractUnruptured aneurysm of sinus of Valsalva is an asymptomatic pathology and diagnosed incidentally. This extremely rare anomaly can be associated with other congenital cardiac anomalies which can make the diagnosis and prognosis even more complex. We are reporting a case of a 12-year-old boy with progressive dyspnea and episodes of syncope. Multimodality imaging confirmed the diagnosis and paved the way for appropriate surgical treatment options.
How Safe Are Radiation Doses in Diagnostic Radiology? A Historical Perspective and Review of Current Evidence
Authors: Moorthy Srikanth 
Published: October 2021

AbstractThe “no dose is safe” linear no-threshold (LNT) model forms the basis for radiation safety in radiology practice. This model has its origins in observations of germline mutations in fruit flies exposed to X-rays. After World War II, quantitative risk estimates of radiation injury are primarily derived from the atomic bomb survivor Life Span Study. Current understanding of tissue response to radiation has raised doubts about the validity of LNT model at low doses encountered in the practice of diagnostic radiology. This article traces the evolution of basic radiation safety concepts and provides a bird's eye view of the Life Span Study and other studies which throw light on the matter. The arguments for an alternative, threshold, or even hermetic models of dose response are examined. The relevance of these developments to the nuclear power industry is also outlined.
Simplified Guide to MR Elastography in Early Detection of Hepatic Fibrosis with Case Reports
Authors: Kharat Amit , Vanpully Nikhith Soman , Jeeson Jacob Cheeran 
Published: October 2021

AbstractThe current unhealthy diets and sedentary lifestyle have led to increase in the prevalence of diabetes and metabolic syndrome globally. Fatty liver is a common occurrence in metabolic syndrome. The liver health is often ignored due to delayed warning signs. Fatty changes of the liver is one of the common findings in ultrasonography. Ultrasound does not detect fibrosis except when cirrhosis is developed. Early stages of fibrosis are asymptomatic with no significant laboratory or preliminary imaging findings. With fibrosis, the elasticity of the liver is reduced and becomes stiffer. Over the years, many techniques have developed to assess the stiffness of the liver, starting from palpation, ultrasonography, and recently developed magnetic resonance elastography (MRE). In this article, we have tried to simplify the concepts of MRE to detect fibrosis and present few case reports. The basic steps involved in generating elastograms and interpretation with some insight on how to incorporate it into the clinical workflow are discussed. MRE is superior to various other available techniques and even offers certain advantages over biopsy. MRE is FDA approved for liver fibrosis since 2009, yet it is hardly used in the Indian setting. MRE is a safe and noninvasive technique to evaluate a large volume of the liver and can be a new norm for the evaluation of fatty liver. Magnetic resonance imaging (MRI)-based elastography techniques hold an exciting future in providing mechanical properties of tissues in various organs like spleen, brain, kidney, and heart.
Role of 18F-FDG PET/CT in Erdheim–Chester Disease in the Era of Multimodality Imaging
Authors: Jois Bhargavi , Ananthasivan Rupa , Rawat Parameswaran R. V. Sudarshan , Rakshit Susmita 
Published: October 2021

AbstractErdheim–Chester disease is a rare disease with systemic non-Langerhans cell histiocytosis, the diagnosis of which with conventional imaging modalities is challenging. We describe a case of a 73-year-old woman who was referred with a progressive history of bilateral proptosis. The magnetic resonance imaging (MRI) orbit demonstrated bilateral orbital masses with optic nerve encasement. A subsequent 18F-FDG PET/CT scan showed multi-organ disease with involvement of the orbits, pericardium, aorta, pararenal fascia, and appendicular bones. Metabolically active, easily accessible areas were selected for CT-guided biopsy. The biopsy showed sheets of foamy histiocytes with the expression of CD 68 and CD 163 consistent with a diagnosis of Erdheim–Chester disease. The FDG PET/CT played a pivotal role in establishing the diagnosis with the assessment of disease extent and further guided in the targeted biopsy.
Crop yields in no-tillage are severely limited by low availability of P and high acidity of the soil in depth
Authors: Bellinaso Roque Junior Sartori , Tiecher Tales , Vargas Jocelina Paranhos Rosa de , Rheinheimer Danilo Santos 
Published: October 2021

The combination of high aluminium (Al) saturation and severe phosphorus (P) deficiency in sub-surface soil in no-tillage (NT) systems is an obstacle hampering crop yields in Brazil. The introduction of NT without proper soil chemical correction affects crop yields in several parts of the country. The aim of this study was to evaluate the changes in soil chemical properties and response of crops to different application methods of lime and phosphate fertiliser in an Ultisol under NT. The field experiment consisted of combining surface and incorporated liming and P application (without P, surface P and P in the sowing line), plus a treatment with incorporated lime and P. The correction of soil acidity and availability of P at depth was effective with the incorporation of lime and phosphate fertiliser. Five months after lime incorporation, it was possible to increase soybean productivity by more than 40% (from 3.9 to 5.6 Mg ha−1). The surface application of P and limestone restricts the correction of soil fertility only in the uppermost soil layer evaluated (up to 5 cm). The relationship between soybean yield and soil chemical properties in different layers clearly demonstrates that neither the 0–10 cm soil layer nor the 0–20 cm soil layer is suitable for diagnosing soil fertility and the crop productive potential in NT system with chemical restrictions in subsurface. Further studies are need to establish critical levels of available P and Al saturation for subsurface soil layers in different soil types under no-tillage.