bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical and laboratory characteristics of Brazilian versus non-Brazilian primary antiphospholipid syndrome patients in AntiPhospholipid Syndrome Alliance for Clinical Trials and InternatiOnal Networking (APS ACTION) clinical database and repository
Authors: de Azevedo Lopes Erivelton , Balbi Gustavo Guimarães Moreira , Tektonidou Maria G. , Pengo Vittorio , Sciascia Savino , Ugarte Amaia , Belmont H. Michael , Gerosa Maria , Fortin Paul R. , Lopez-Pedrera Chary , Ji Lanlan , Cohen Hannah , de Jesús Guilherme Ramires , Branch D. Ware , Nalli Cecilia , Petri Michelle , Rodriguez Esther , Kello Nina , Ríos-Garcés Roberto , Knight Jason S. , Atsumi Tatsuya , Willis Rohan , Bertolaccini Maria Laura , Erkan Doruk , Andrade Danieli ,   APS ACTION
Published: October 2021

Abstract
Background
Antiphospholipid syndrome (APS) is characterized by episodes of thrombosis, obstetric morbidity or both, associated with persistently positive antiphospholipid antibodies (aPL). Studying the profile of a rare disease in an admixed population is important as it can provide new insights for understanding an autoimmune disease. In this sense of miscegenation, Brazil is characterized by one of the most heterogeneous populations in the world, which is the result of five centuries of interethnic crosses of people from three continents. The objective of this study was to compare the clinical and laboratory characteristics of Brazilian vs. non-Brazilian primary antiphospholipid syndrome (PAPS) patients.

Methods
We classified PAPS patients into 2 groups: Brazilian PAPS patients (BPAPS) and PAPS patients from other countries (non-BPAPS). They were compared regarding demographic characteristics, criteria and non-criteria APS manifestations, antiphospholipid antibody (aPL) profile, and the adjusted Global Antiphospholipid Syndrome Score (aGAPSS).

Results
We included 415 PAPS patients (88 [21%] BPAPS and 327 [79%] non-BPAPS). Brazilian patients were significantly younger, more frequently female, sedentary, obese, non-white, and had a higher frequency of livedo (25% vs. 10%, p < 0.001), cognitive dysfunction (21% vs. 8%, p = 0.001) and seizures (16% vs. 7%, p = 0.007), and a lower frequency of thrombocytopenia (9% vs. 18%, p = 0.037). Additionally, they were more frequently positive for lupus anticoagulant (87.5% vs. 74.6%, p = 0.01), and less frequently positive to anticardiolipin (46.6% vs. 73.7%, p < 0.001) and anti-ß2-glycoprotein-I (13.6% vs. 62.7%, p < 0.001) antibodies. Triple aPL positivity was also less frequent (8% vs. 41.6%, p < 0.001) in Brazilian patients. Median aGAPSS was lower in the Brazilian group (8 vs. 10, p < 0.0001). In the multivariate analysis, BPAPS patients still presented more frequently with livedo, cognitive dysfunction and sedentary lifestyle, and less frequently with thrombocytopenia and triple positivity to aPL. They were also less often white.

Conclusions
Our study suggests a specific profile of PAPS in Brazil with higher frequency of selected non-criteria manifestations and lupus anticoagulant positivity. Lupus anticoagulant (not triple positivity) was the major aPL predictor of a classification criteria event.
Improving visitor satisfaction in Egypt’s Heliopolis historical district
Authors: Abusaada Hisham , Elshater Abeer 
Published: October 2021

AbstractThis study employed applied thematic analysis (ATA) and importance-performance analysis (IPA) to measure visitor satisfaction in city streets. Forty-two elements that significantly influence visitors’ responses to streets and environments were included in five groups characterised by circumstances, characteristics, and indicators. Ibrahim Al-Lakani Street’s atmosphere satisfaction was measured by using coherent research methods. This investigation can assist designers in developing the morphological and social composition necessary to restore a street’s atmosphere and visitor satisfaction. This study contributes to the literature in two ways. First, it examines the relationships between street characteristics and visitor satisfaction in city streets regarding situations, atmospheres and social characteristics that shape these streets. Second, this study integrates ATA and IPA to create a tool for evaluating the significance, performance, and satisfaction of street situations, socio-morphological characteristics and street and visitor responses.
Gertrude and Ludwig's Italian Adventure
Authors: Ballerini Luigi 
Published: October 2021

Abstract
A survey of the ingredients and paratextual elements that converged in Charles Bernstein's “Gertrude and Ludwig's Bogus Adventure,” occasioned by the translation of the poem into Italian. Historical hints and literary echoes are shown to be not merely juxtaposed but intertwined with trivia drawn from B Hollywood movies and accounting for the title itself of the poem. As the making of meaning, especially in the second part of the text, is driven by phonetic equivalences rather than by referential affinities, readers are alerted that ontophony has been chosen as a modus operandi over any attempt at contentual re-creation. The alliterative deployment of the letter p, for instance, has been retained, though this has caused the scene of the poem to transfer from a baseball park to a painter's studio. A suggestion is also put forward that in Bernstein's poetry, the step-by-step logic of Wittgenstein's Tractatus can be made to dialogue with Gertrude Stein's obsessive brushstroke writing.
The Well-Hung & Well-Stretched Language-Tongues of New York
Authors: Joris Pierre 
Published: October 2021

Abstract
This text was written in French as a preface to Charles Bernstein's Pour ainsi dire (So to Speak), a selection of his work translated by Habib Tengour (Algiers, Algeria: Apic Éditions, 2019). Translating it (back?) into English is problematic, as the author does as he claims the addressee does: he puns & plays with words—which is a well-known no-no when it comes to translating. This translation tries to keep this playfulness alive, at the risk of befuddling the audience (but what are audiences for, anyway? Illumination goes through befuddling). Thus the title in French was “Les langues bien pendues and bien tendues de New York.” Now a “langue bien pendue” refers to a rich & ready tongue, a great gabber never at a loss for words, though the title means langue not as “tongue” but as the linguistic thing: “language.” Literally, the expression gives “well-hung”—& that seems to be the easiest way of punning shockingly back into New Yorkese.
Bail Out Poetry
Authors: Lang Abigail 
Published: October 2021

Abstract
Originally written as an afterword to a book-length translation of poems by Charles Bernstein, this piece was meant to introduce his recent poetry and poetics to a French audience. It does so by pondering the twin economic and nautical senses contained in the title Bernstein suggested for the collection: Poetry Bailout (in French, Renflouer la poésie). What is the value of poetry? What are its uses? These are questions which have underpinned Bernstein's work. In an early essay, adapting a statement by Simone Weil, Bernstein posited that poetry draws its social—or antisocial—power from the fact that “it is ceaselessly creating a scale of values ‘that is not of this world.’” One way it does that is by intensifying the experience of reading. Placing his recent poetics under the aegis of Poe, Bernstein has managed to balance poetry's social and aesthetic functions by cultivating the uses of aesthetics, reconciling pragmatism with unabashed aestheticism.
A Source Which Is Also a Translation: Toward an Expanded- Yiddish Poetics, with Special Reference to Charles Bernstein
Authors: Resnikoff Ariel 
Published: October 2021

Abstract
The present essay contextualizes the poet, scholar, editor, and translator Charles Bernstein (b. 1950), as an artist and practitioner working within a speculative translingual (language-crossing) field and tradition of expanded Yiddish. Reading Bernstein in relation to other expanded-Yiddish figures, such as his elders, Hannah Weiner (1928–77) and Jerome Rothenberg (b. 1931), and ancestor, Walter Benjamin (1892–1940), among others, this essay makes a case for Bernstein as a writer who works from a position of antinomian Jewish translational originlessness, and a diasporic poetics of “need” (à la Charles Reznikoff), in which every source can be understood as a translation and every translation might be treated as a potential source. The coda of the essay addresses the stakes of Bernstein's praxes from the perspective of widespread modern and contemporary anti-Semitism and Jewish self-hatred and concludes with the first ever translation of Bernstein's poetry into Yiddish proper.
Ten Plus Ways of Reading Charles Bernstein: Improvisations on Aphoristic Cores
Authors: Huang Yunte 
Published: October 2021

Abstract
Composed as a series of improvisations, this is a modular essay that examines, ponders, and responds to the radical poetics of Charles Bernstein's work from multiple perspectives, including dysraphism, aphorism, wit, and echopoetics. It also situates Bernstein in the long tradition of innovative American poetics extending from Ezra Pound and Gertrude Stein to Charles Olson and Susan Howe.
Learning-based synthetic dual energy CT imaging from single energy CT for stopping power ratio calculation in proton radiation therapy
Authors: Charyyev Serdar , Wang Tonghe , Lei Yang , Ghavidel Beth , Beitler Jonathan J , McDonald Mark , Curran Walter J , Liu Tian , Zhou Jun , Yang Xiaofeng 
Published: October 2021

Objective:
Dual energy CT (DECT) has been shown to estimate stopping power ratio (SPR) map with a higher accuracy than conventional single energy CT (SECT) by obtaining the energy dependence of photon interactions. This work presents a learning-based method to synthesize DECT images from SECT image for proton radiotherapy.

Methods:
The proposed method uses a residual attention generative adversarial network. Residual blocks with attention gates were used to force the model to focus on the difference between DECT images and SECT images. To evaluate the accuracy of the method, we retrospectively investigated 70 head-and-neck cancer patients whose DECT and SECT scans were acquired simultaneously. The model was trained to generate both a high and low energy DECT image based on a SECT image. The generated synthetic low and high DECT images were evaluated against the true DECT images using leave-one-out cross-validation. To evaluate our method in the context of a practical application, we generated SPR maps from synthetic DECT (sDECT) using a dual-energy based stoichiometric method and compared the SPR maps to those generated from DECT. A dosimetric comparison for dose obtained from DECT was performed against that derived from sDECT.

Results:
The mean of mean absolute error, peak signal-to-noise ratio and normalized cross-correlation for the synthetic high and low energy CT images was 36.9 HU, 29.3 dB, 0.96 and 35.8 HU, 29.2 dB, and 0.96, respectively. The corresponding SPR maps generated from synthetic DECT showed an average normalized mean square deviation of about 1% with reduced noise level and artifacts than those from original DECT. Dose–volume histogram (DVH) metrics for the clinical target volume agree within 1% between the DECT and sDECT calculated dose.

Conclusion:
Our method synthesized accurate DECT images and showed a potential feasibility for proton SPR map generation.

Advances in knowledge:
This study investigated a learning-based method to synthesize DECT images from SECT image for proton radiotherapy.
Quality Regulation on Two-Sided Platforms: Exclusion, Subsidization, and First-Party Applications
Authors: Huang Peng , Lyu Gaoyan , Xu Yi 
Published: October 2021

Managing the quality of complementary applications is vital to the success of a two-sided platform. While prior research has focused solely on restricting platform access based on a quality threshold, we compare three quality regulation strategies: (1) the platform excludes access to low-quality complementors, (2) it provides a fixed amount of subsidy to high-quality complementors, and (3) it develops its own high-quality applications in addition to those from third-party complementors. Our analyses reveal that the widely adopted exclusion strategy is a special case of the subsidization strategy, and it does not always benefit the platform. In contrast, both subsidization and first-party applications strategies render the platform owner better off, with higher profits, higher average quality, and a larger consumer network, but only subsidization always improves social welfare. In addition, the trade-off between subsidization and first-party applications strategies depends on the development cost of first-party applications and the fraction of high-quality complementors, but the relationship is not monotonic. Our results demonstrate that the platform does not have to sacrifice application quantity for higher application quality. With the right choices, it can profitably improve both measures simultaneously. This research provides concrete guidelines to help platform managers make decisions about regulating the quality of complementary applications.This paper was accepted by Anandhi Bharadwaj, information systems.
Comparing medication use and patient satisfaction in conscious sedation nursing practices: a retrospective study
Authors: Parone Linda , Rawal Sahil , Ellis Allison , Peterson Bryant , Escalante Lourdes , Sharma Ravi , Pandya Bhavi , Kumar Arnav , Panchal Hemang B , Prakash Meghanaprakash Hiriyur , Yadav Ritu , Kanwar Nidhi , Sawant Abhishek C 
Published: October 2021

Background Moderate sedation is performed frequently in the hospital setting for same-day, invasive procedures. The primary administrators of moderate sedation are nurses who have been trained to administer medication based on patient responsiveness, airway, ventilation and cardiovascular function. This study evaluated the safety and efficacy of nurse-administered conscious sedation by assessing medication use, clinical outcomes and patient satisfaction. Methods Data from same-day, elective procedures in the cardiac catheterisation laboratory and interventional radiology departments were collected, including comorbidities, procedural characteristics and post-sedation questionnaires. Results Procedure duration was found to be longer in the cardiac catheterisation laboratory (55 minutes; interquartile range: 37–81 minutes) than in interventional radiology (24 minutes; interquartile range 16–45 minutes; P value of <0.001). Associated comorbidities in the cardiac catheterisation laboratory compared to interventional radiology included hypertension in 103 patients (78% vs 44.7%, P=<0.001), heart failure in 23 patients (17.4% vs 3.2%, P=<0.001), arrhythmias in 20 patients (15.2% vs 1%, P=0.1), and chronic kidney disease in 44 patients (33.3% vs 14.9%, P=0.002). Conclusions: Patients receiving conscious sedation while undergoing procedures in the cardiac catheterisation laboratory and interventional radiology were found to have no adverse clinical outcomes, as evidenced by the absence of reversal agents and advanced airway requirements. The procedural duration of the catheterisation procedures were significantly longer than interventional radiology and patients received overall less sedation medication.
Comfort Evaluation and Position Optimization of the Clutch Pedal in Agricultural Machinery Based on a Multi-Level Evaluation System
Authors: Qin Zengzhi , Shang Yujun , Jiang Wei , Li Hang , Xu Hongmei , Zhang Guozhong 
Published: October 2021

HighlightsComfort evaluation and position parameter optimization of the clutch pedal were conducted.A comprehensive evaluation system was established for sitting comfort and operating comfort.A single-factor test and a response surface optimization test were carried out.Pedal inclination and its left-right distance synergistically influenced operating comfort.Abstract. The clutch pedal is the most frequently used control device in agricultural machinery and is an important component that affects operating comfort and safety. This study focused on the comfort evaluation and position parameter optimization of the clutch pedal based on a multi-degree-of-freedom test platform of an agricultural machinery cab. First, the H point (hip point) was determined based on a human body model of the operator’s sitting posture as a reference. Two position parameters were then determined: the pedal inclination angle, and the left-right distance of the pedal relative to the operator’s centerline. On this basis, a comprehensive evaluation system for sitting comfort and operating comfort was established. Single-factor tests were used to determine the comfort range and optimal levels of the two position parameters. A response surface optimization was then performed to determine the optimal parameter combination, and a first-order regression model of the response surface was established and corrected using the variance analysis method. The analysis results showed that the pedal inclination angle and its interaction with the left-right distance had a significant effect on comfort (a = 0.05). Based on the evaluation results, the mechanism underlying the influence of the position parameters on pedal comfort was analyzed. Finally, optimization and verification of the pedal position parameters were performed. The results showed that the expected comprehensive score for pedal comfort was 0.831, with an average relative error of 3.64% from the measured value, indicating that the optimization of the position parameters was reliable. The findings of this study may provide a reference for the optimal design of clutch pedals in agricultural machinery. Keywords: Agricultural machinery, Clutch pedal, Comfort evaluation, Parameter optimization, Response surface method.
Enhanced optical nonlinearity in a silicon–organic hybrid slot waveguide for all-optical signal processing
Authors: Wang Yonghua , He Su , Gao Xiaoyan , Ye Piaopiao , Lei Lei , Dong Wenchan , Zhang Xinliang , Xu Ping 
Published: October 2021

Silicon photonic integrated devices used for nonlinear optical signal processing play a key role in ultrafast switching, computing, and modern optical communications. However, current devices suffer from limited operation speeds and low conversion efficiencies due to the intrinsically low nonlinear index of silicon. In this paper, we experimentally demonstrate enhanced optical nonlinearity in a silicon–organic hybrid slot waveguide consisting of an ultranarrow slot waveguide coated with a highly nonlinear organic material. The fabricated slot area is as narrow as 45 nm, which is, to the best of our knowledge, the narrowest slot width that has been experimentally reported in silicon slot waveguides. The nonlinear coefficient of the proposed device with a length of 3 mm is measured to be up to

1.43
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10

6

W

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1

km

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1

. Based on the nanostructure design, the conversion efficiencies of degenerate four-wave mixing showed enhancements of more than 12 dB and 5 dB compared to those measured for an identical device without the organic material and a silicon strip waveguide, respectively. As a proof of concept, all-optical canonical logic units based on the prepared device with two inputs at 40 Gb/s are analyzed. The obtained logic results showed clear temporal waveforms and wide-open eye diagrams with error-free performance, illustrating that our device has great potential for use in high-speed all-optical signal processing and high-performance computing in the nodes and terminals of optical networks.
Near-infrared electroluminescence of AlGaN capped InGaN quantum dots formed by controlled growth on photoelectrochemical etched quantum dot templates
Authors: Wei Xiongliang , Al Muyeed Syed Ahmed , Xue Haotian , Palmese Elia , Song Renbo , Tansu Nelson , Wierer Jonathan J. 
Published: October 2021

Near-infrared electroluminescence of InGaN quantum dots (QDs) formed by controlled growth on photoelectrochemical (PEC) etched QD templates is demonstrated. The QD template consists of PEC InGaN QDs with high density and controlled sizes, an AlGaN capping layer to protect the QDs, and a GaN barrier layer to planarize the surface. Scanning transmission electron microscopy (STEM) of Stranski–Krastanov (SK) growth on the QD template shows high-In-content InGaN QDs that align vertically to the PEC QDs due to localized strain. A high-Al-content

Al

0.9

Ga

0.1

N

capping layer prevents the collapse of the SK QDs due to intermixing or decomposition during higher temperature GaN growth as verified by STEM. Growth of low-temperature (830°C) p-type layers is used to complete the p-n junction and further ensure QD integrity. Finally, electroluminescence shows a significant wavelength shift (800 nm to 500 nm), caused by the SK QDs’ tall height, high In content, and strong polarization-induced electric fields.
Mitochondrial respiratory chain and Krebs cycle enzyme function in human donor livers subjected to end-ischaemic hypothermic machine perfusion
Authors: Abudhaise Hamid , Taanman Jan-Willem , DeMuylder Peter , Fuller Barry , Davidson Brian R. 
Published: October 2021

Introduction
Marginal human donor livers are highly susceptible to ischaemia reperfusion injury and mitochondrial dysfunction. Oxygenation during hypothermic machine perfusion (HMP) was proposed to protect the mitochondria but the mechanism is unclear. Additionally, the distribution and uptake of perfusate oxygen during HMP are unknown. This study aimed to examine the feasibility of mitochondrial function analysis during end-ischaemic HMP, assess potential mitochondrial viability biomarkers, and record oxygenation kinetics.

Methods
This was a randomised pilot study using human livers retrieved for transplant but not utilised. Livers (n = 38) were randomised at stage 1 into static cold storage (n = 6), hepatic artery HMP (n = 7), and non-oxygen supplemented portal vein HMP (n = 7) and at stage 2 into oxygen supplemented and non-oxygen supplemented portal vein HMP (n = 11 and 7, respectively). Mitochondrial parameters were compared between the groups and between low- and high-risk marginal livers based on donor history, organ steatosis and preservation period. The oxygen delivery efficiency was assessed in additional 6 livers using real-time measurements of perfusate and parenchymal oxygen.

Results
The change in mitochondrial respiratory chain (complex I, II, III, IV) and Krebs cycle enzyme activity (aconitase, citrate synthase) before and after 4-hour preservation was not different between groups in both study stages (p > 0.05). Low-risk livers that could have been used clinically (n = 8) had lower complex II-III activities after 4-hour perfusion, compared with high-risk livers (73 nmol/mg/min vs. 113 nmol/mg/min, p = 0.01). Parenchymal pO2 was consistently lower than perfusate pO2 (p ≤ 0.001), stabilised in 28 minutes compared to 3 minutes in perfusate (p = 0.003), and decreased faster upon oxygen cessation (75 vs. 36 minutes, p = 0.003).

Conclusions
Actively oxygenated and air-equilibrated end-ischaemic HMP did not induce oxidative damage of aconitase, and respiratory chain complexes remained intact. Mitochondria likely respond to variable perfusate oxygen levels by adapting their respiratory function during end-ischaemic HMP. Complex II-III activities should be further investigated as viability biomarkers.