bluuebunny/crossref_metadata_2025_split huggingface dataset:
Technologies Employed Within the Healthcare Setting During the COVID-19 Pandemic For A Continuation of Care: Emerging CoP
Authors: Sturgeon Delia Cassandra 
Published: July 2021

In early 2020, the coronavirus (COVID-19	) was declared a pandemic (“WHO Director-General’s opening remarks at the media briefing on COVID-19 – 11 March 2020” 2020), as the respiratory disease spread and productively infected patients generating havoc in the health sector (Chan 2020). As a response, digital services were offered to patients to allow the continuation of care and digital tools were adopted to assist health professionals (HP) in maintaining a social distance and minimising viral transmission (Meinert, Milne-Ives, Surodina and Lam 2020). Although much is discussed of the technologies employed during this period, changes in practices adopted by HP have been largely overlooked.
Applying technology to the clinical setting improves the interprofessional community of practice as HP can collaborate on clinical decisions improving clinical outcomes (Waldman, Waldman, Waldman and Abuabara 2020).
This literature review takes an exploratory stance into the technologies employed by HP during the first few months of the COVID-19 pandemic to investigate how their professional development has been affected. The study aimed to clarify the role of technologies utilised during the COVID-19 pandemic in the health sector and discuss the extent to which practice differed from the traditional means. Moreover, the study sought to shed a light on how technology assists HP in their role and professional development during the pandemic and possible thereafter.
Core literature is discussed to identify whether emerging CoP has evolved within health communities due to the technology revolution in this short period and whether the technology employed shall be considered permanently to ensure best practices. The data provide convincing evidence that technology changed the way health care is delivered. Moreover, the findings show that COVID-19 pandemic has created a CoP between HP to share best practices in this new era that may lead to a shift in their professional development long after the pandemic has ended.
Fire Resistant Geopolymers Based on Several Clays Mixtures
Authors: Gharzouni Ameni , Alizé Clément , Rossignol Sylvie 
Published: July 2021

This chapter aims to highlight the effect of clay mixture mineral composition and alkali concentration of potassium alkaline solutions on the thermal behavior of geopolymer materials. For this, three mixtures composed of kaolin (pure, impure kaolin or mixture of both), calcium carbonate, sand and potassium feldspar and three potassium alkaline silicate solutions with different concentrations were used (5, 6 and 7 mol.L−1). At first, the effect of rotary calcination parameters at 750°C such as the dwell time (30, 60, 120 and 180 min) and weight powder (100, 400 and 500 g) was investigated. It was demonstrated that the kaolin dehydroxylation is quasi complete (> 90%) and do not significantly depend on the dwell time and powder weight. Whereas the carbonate decomposition degree increases with the increase of dwell time and the decrease of powder weight but still not complete (<80%). These differences influence the feasibility of consolidated materials. Indeed, a flash setting occurs for samples based mixtures with high calcium carbonate decomposition degree (> 50%) and low wettability values (500 μL/g) for the three used alkaline solutions. The thermal behavior at 1000°C depends on the chemical composition of the aluminosilicate source and the concentration of alkaline solution. A conservation of the compressive strength at 43 MPa after thermal treatment at 1000°C of geopolymers based on mixture of pure and impure kaolin and a low potassium concentration solution (5 mol.L−1) was evidenced.
Efficiency of Autologous Egg Cryopreservation: Eight Years’ Experiences and Clinical Outcomes
Authors: T. Wang Cassie , Niu Xiangli , Ruan Qiuyan , Wang Wei-Hua 
Published: July 2021

Oocyte cryopreservation is one of the state-of-art technologies in human reproductive medicine, which brings opportunities for women to preserve their fertility. In the present study, we analyzed the efficiency and outcomes of 8 years’ autologous egg cryopreservation: Frozen oocytes were warmed from 120 cycles and oocyte survival, fertilization, blastocyst development, clinical pregnancy, embryo implantation, live birth rates and birth weights were collected based on the patients’ ages of <35, 35–37 and > 37 years old. The details of oocyte cryopreservation and the efficiency were further analyzed based on different patient categories. During the study period, 849 oocytes from 120 cycles were warmed. Oocyte survival, fertilization, and blastocyst development were not affected by women’s ages at the time of cryopreservation. However, number of patients without blastocyst formation was significantly (P < 0.05) higher in patients >37 years old (31.2%) than that in patients <35 years old (13.1%). Higher live birth rates were observed in patients <35 (51.1%) and 35–37 (46.7%) years old than in patients >37 years old (28.6%) after fresh embryo transfer. Some patients did not have blastocysts mainly due to low fertilization by poor sperm or small number of oocytes warmed. These results indicate that the efficiency of oocyte cryopreservation, evaluated by live birth and embryo implantation rates is affected by women’s age, number of oocytes warmed and sperm quality.
Que conclure de neuf années de suivi sur la population de Vertigo de Des Moulins Vertigo moulinsiana (Dupuy, 1849) ?
Authors: CUCHERAT Xavier , HUBERT Baptiste , VANAPPELGHEM Cédric 
Published: July 2021

La présence du Vertigo de Des Moulins Vertigo moulinsiana (Dupuy, 1848) a justifié l’inscription du site du marais de la Grenouillère dans le réseau Natura 2000 et a motivé le suivi de la population de cet escargot inscrit à l’Annexe II de la Directive Habitats-Faune-Flore. Un suivi a été mené pendant neuf ans sur l’espèce à l’aide d’un protocole non-invasif. Les données ont été traitées à l’aide de techniques statistiques adaptées. La fluctuation de l’abondance du Vertigo de Des Moulins est faible à l’échelle du site, mais varie selon les transects. La variabilité des abondances relevées a une incidence sur la précision des estimations et ne permet pas de conclure sur l’état de conservation de l’espèce sur le site. En effet, l’espèce est capable de restaurer ses abondances d’une année sur l’autre, même lorsque les effectifs sont très bas. La recherche de facteurs explicatifs ne permet pas de dire quelle variable mesurée influence le plus l’espèce, dans la mesure où leur significativité change selon les années de suivi. La pertinence du suivi est discutée et des perspectives sont proposées pour pouvoir établir un nouveau protocole adapté.
Comparative population genetics of swimming crab host (Portunus pelagicus) and common symbiotic barnacle (Octolasmis angulata) in Vietnam
Authors: Dang Binh Thuy , Truong Oanh Thi , Tran Sang Quang , Glenner Henrik 
Published: July 2021

Background
By comparing spatial geographical structures of host populations with that of their symbionts light can be shed on their biological interactions, and the degree of congruence between host and symbiont phylogeographies should reflect their life histories and especially dispersal mechanisms.

Methods
Here, we analyzed the genetic diversity and structure of a host, the blue swimming crab, Portunus pelagicus, and its symbiotic pedunculate barnacle Octolasmis angulata from six location sites representing three geographic regions (north, central and south) along the Vietnam coastline. High levels of congruence in their phylogeographic patterns were expected as they both undergo planktonic larval stages.

Results
Based on the COI mtDNA markers, O. angulata populations showed higher genetic diversity in comparison with their host P. pelagicus (number of haplotype/individuals, haplotype and nucleotide diversity are 119/192, 0.991 ± 0.002 and 0.02; and 89/160, 0.913 ± 0.02 and 0.015, respectively). Pairwise Fst and AMOVA analyses showed a more pronounced population structure in the symbiotic barnacle than in its crab host. The DAPC analyses identified three genetic clusters. However, both haplotype networks and scatter plots supported connectivity of the host and the symbiotic barnacle throughout their distribution range, except for low subdivision of southern population. Isolation by distance were detected only for the symbiont O. angulata (R2 = 0.332, P = 0.05), while dbMEM supported spatial structure of both partners, but only at MEM-1 (Obs. 0.2686, P < 0.01 and Obs. 0.2096, P < 0.01, respectively).
Improved strategy for jet‐in‐air cell sorting with high purity, yield, viability, and genome stability
Authors: Song Xinghui , Wang Jiajia , Li Yanwei , Xing Yueting , Guo Chun , Huang Yingying , Xu Lintao , Hu Hu , Wang Lin‐lin 
Published: July 2021

Flow cytometric sorting is a vital tool in biological research and clinical diagnostics. Theoretically, a high‐speed jet‐in‐air sorter is a fluorescent‐activated cell sorting sorter that ideally processes cells with high purity, yield, and viability. However, high‐speed jet‐in‐air sorting is a complex process due to its inherent requirements for high fluidic stability and electronic and timing precision. Here, we report that an additional manual correction of drop delay leads to improved cell yield. Adding 2% FBS to the loading buffer had no significant effect on the fate of sorted cells in 4 h. However, the addition of a suitable concentration of FBS/BSA in the collecting buffer resulted in a notable increase in cell count and proliferation and a significant decrease in cell apoptosis for cell lines and primary cells. Moreover, the level of gene expression remained steady in the 5% FBS collecting buffer. In summary, here we demonstrate techniques that can be easily followed to refine sorted yields of healthy cells.
EPHB4 mutation causes adult and adolescent‐onset primary lymphedema
Authors: Greene Arin K. , Brouillard Pascal , Sudduth Christopher L. , Smits Patrick J. , Konczyk Dennis J. , Vikkula Miikka 
Published: July 2021

AbstractPrimary lymphedema results from the anomalous development of the lymphatic system and typically presents during infancy, childhood, or adolescence. Adult‐onset primary lymphedema is rare and mutations associated with this condition have not been identified. The purpose of this investigation was to search for variants that cause adult‐onset primary lymphedema. We discovered an autosomal dominant EPHB4 mutation in a patient who developed unilateral leg lymphedema at age 39 years; the same mutation affected his son who presented with the disease at 14 years of age.
Cyclic Amplification of the Afterglow Luminescent Nanoreporter Enables the Prediction of Anti‐cancer Efficiency
Authors: Wang Youjuan , Song Guosheng , Liao Shiyi , Qin Qiaoqiao , Zhao Yan , Shi Linan , Guan Kesong , Gong Xiangyang , Wang Peng , Yin Xia , Chen Qian , Zhang Xiao‐Bing 
Published: July 2021

AbstractWe developed a cyclic amplification method for an organic afterglow nanoreporter for the real‐time visualization of self‐generated reactive oxygen species (ROS). We promoted semiconducting polymer nanoparticles (PFODBT) as a candidate for emitting near‐infrared afterglow luminescence. Introduction of a chemiluminescent substrate (CPPO) into PFODBT (PFODBT@CPPO) resulted in a significant enhancement of afterglow intensity through the dual cyclic amplification pathway involving singlet oxygen (1O2).1O2produced by PFODBT@CPPO induced cancer cell necrosis and promoted the release of damage‐related molecular patterns, thereby evoking immunogenic cell death (ICD)‐associated immune responses through ROS‐based oxidative stress. The afterglow luminescent signals of the nanoreporter were well correlated with light‐driven1O2generation and anti‐cancer efficiency. This imaging strategy provides a non‐invasive tool for predicting the therapeutic outcome that occurs during ROS‐mediated cancer therapy.
Nano cobalt ferrite encapsulated‐silica particles bearing melamine as an easily recyclable catalyst for the synthesis of dihydropyrano[2,3‐c]pyrazoles under green conditions
Authors: Dadaei Mahla , Naeimi Hossein 
Published: July 2021

AbstractIn this research, it was displayed an efficient method for synthesis of 6‐amino‐2,4‐dihydropyrano[2,3‐c] pyrazol‐5‐carbonitrile derivatives by using CoFe2O4 silica supported bearing melamine as a magnetic nanocatalyst. This nanocomposite was prepared in several steps and characterized by XRD, FT‐IR, SEM, EDX, VSM, and TGA techniques. The catalyst has a large active site that has functionalized on the surface of nanostructure. The advantages of this magnetic nanocatalyst are simple achievable, effective heterogeneous nanocatalyst, non‐toxic, small amount of catalyst used, resulted products with high yields and short reaction times, easy work up, and reusability. The central core nanoparticles are excellent chemical and magnetic stability. Therefore, the magnetic moment of cobalt ferrite relaxes much slower than the magnetite with the similar particle size.
Sustainable lignin‐based polyols as promising thermal energy storage materials
Authors: Perez‐Arce Jonatan , Serrano Angel , Dauvergne Jean‐Luc , Centeno‐Pedrazo Ander , Prieto‐Fernandez Soraya , Palomo Del Barrio Elena , Garcia‐Suarez Eduardo J. 
Published: July 2021

AbstractSix lignin‐based polyols (LBPs) have been prepared by cationic ring opening polymerization of an oxirane in the presence of an organosolv lignin in tetrahydrofuran (THF) as reaction media and co‐monomer. The prepared LBPs have been characterized and tested for the first time as phase change materials (PCMs) for thermal energy storage (TES) at low temperature. It was found a strong influence of the LBPs composition on their performance to storage thermal energy. Thus, LBPs with higher THF wt% content and lower oxirane/THF mass ratio exhibit the highest latent heats. Furthermore, a clear inversely proportional trend between the oxirane/THF mass ratio and the melting temperatures of the prepared LBPs was noticed. Among the prepared LBPs, the highest obtained latent heat was 53.7 J/g demonstrating the potential application of lignin as feedstock for PCMs preparation. To the best of our knowledge, this is the first time that a biomass derived PCM based on lignin has been studied and considered for TES applications at low temperature. LBPs show energetic solid–liquid transitions that point out their promising potential as bio‐PCMs. This work paves the way to introduce new bio‐based PCMs from lignin in TES systems, for example, in a more sustainable construction sector.
Psychiatric problems during the COVID‐19 pandemic in children with autism spectrum disorder
Authors: Vasa Roma A. , Singh Vini , Holingue Calliope , Kalb Luther G. , Jang Yeon , Keefer Amy 
Published: July 2021

AbstractChildren with autism spectrum disorder (ASD) are at elevated risk for psychiatric problems in response to the COVID‐19 pandemic. This risk is due to their high rates of pre‐pandemic psychiatric comorbidities and the pandemic's disruption to routines and access to necessary supports. Prior research has indicated that children with ASD may experience a worsening of specific psychiatric symptoms in response to COVID‐19, though this body of work is limited in scope. The present study expands this literature by examining specific types of psychiatric problems that emerged about 2 months after the onset of the pandemic, and risk factors predicting changes in these psychiatric symptoms. Parents of children with a confirmed ASD diagnosis (N = 257), who enrolled in a clinic registry at an outpatient specialty autism center, were included in this study. All data were gathered online via customized and standardized questionnaires. Results showed that 59% of children experienced either a worsening of their pre‐pandemic psychiatric diagnoses and/or the development of new psychiatric symptoms during the pandemic. Multivariable regression models indicated that risk factors for increased psychiatric problems included child understanding of COVID‐19, COVID‐19 illness in the family, low family income, and elevated parental depression and anxiety symptoms (all p < 0.05). Findings from this study emphasize the urgent need to provide effective and accessible psychiatric services for children with ASD and their families during and after the pandemic.Lay summaryChildren with ASD are at high risk for psychiatric problems during the COVID‐19 pandemic. We found that 59% of children in our clinical sample are experiencing increased psychiatric problems. The child's understanding of COVID‐19, COVID‐19 illness in the family, low family income, and depression and anxiety symptoms in the parent increase the risk for poor mental health during the pandemic. These findings indicate the importance of helping children with ASD access mental health treatment during COVID‐19.
Optimization of Connective Tissue Graft Length by Graft Splitting: A Case Series
Authors: Martin‐Cabezas Rodrigo , Deschamps‐Lenhardt Sonia , Huck Olivier 
Published: July 2021

IntroductionThe aim of this case series was to assess the feasibility of a graft modification to increase its length when treating multiple adjacent gingival recessions with only one harvesting site at the palate and respecting the safety zone.Case SeriesNineteen recessions were treated in four consecutive patients with a modified coronally advanced tunnel and a modified connective tissue graft. An 8‐mm height connective tissue graft was harvested by the single‐incision technique, the graft was split longitudinally, achieving 4‐mm height and double the length. Changes in recession depth, keratinized tissue height, mean and complete root coverage, and esthetic score were analyzed at 6 months. The technique allows to harvest a connective tissue graft up to 58‐mm length with a single palatal site. Complete root coverage was achieved in 15/19 recessions (78.94%), with a mean root coverage of 82.90%. The mean recession depth was reduced by 1.31 mm and the keratinized tissue increased by 0.69 mm. The esthetic outcome score was 9.26/10.ConclusionThis graft modification technique allows increasing significantly the graft length up to 58 mm without any modification of the surgical harvesting procedure. Therefore, it can be suggested to reduce the morbidity.
An examination of personality traits as predictors of electronic word‐of‐mouth diffusion in social networking sites
Authors: Moisescu Ovidiu‐Ioan , Dan Ioana , Gică Oana‐Adriana 
Published: July 2021

AbstractNowadays, in the technological era, social networking sites (SNSs) have the capacity to influence, through electronic word‐of‐mouth (eWOM), consumers' attitudes towards brands and companies. Consequently, eWOM via SNSs has become an important marketing communication tool for facilitating consumer interaction, acquiring new customers, and enhancing customer loyalty. However, despite the extensive research conducted to identify and depict the antecedents of eWOM, the prediction of whether and to what extent brand‐related content will be shared on SNSs, based on consumers' personality traits, is still an area of marketing that needs further research. Grounded in the trait theory of personality, the current study's objective is to analyze the impact of SNS users' materialism, narcissism, self‐esteem, and extraversion on eWOM diffusion, both directly and indirectly, mediated by referral visit behavior and knowledge‐based validation. For this, an online survey was conducted among a sample of 301 Romanian Facebook users, data being analyzed using partial least squares structural equation modeling. Our findings reveal a high prevalence of eWOM among SNS users, more than one‐third of the investigated sample having a tendency to pass along information about products and brands in SNSs. The results show that eWOM diffusion in SNSs is positively predicted (directly and indirectly) by users' materialism, extraversion, and narcissism, while the total effect of self‐esteem on eWOM diffusion is insignificant. The research provides useful insights for online marketers, concerning psychographic segmentation and social media communication, as well as for SNS developers, with regard to improving the segmentation and targeting tools offered to online marketers.
Efficacy and safety of glycoproteinIIb/IIIainhibitors in addition toP2Y12inhibitors inST‐segment elevation myocardial infarction: A subanalysis of thePOPularGenetics trial
Authors: Tavenier Anne H. , Claassens Daniel M. F. , Hermanides Renicus S. , Vos Gerrit J. A. , Bergmeijer Thomas O. , Kelder Johannes C. , Deneer Vera H. M. , van 't Hof Arnoud W. J. , ten Berg Jurriën M. 
Published: July 2021

AbstractBackgroundGlycoprotein IIb/IIIa inhibitors (GPI) are still used in patients with ST‐segment elevation myocardial infarction (STEMI) who undergo primary percutaneous coronary intervention (PCI), although discussion about its clinical benefit is ongoing.MethodsGPI use was analyzed in this subanalysis of the POPular Genetics trial, which randomized STEMI patients toCYP2C19genotype‐guided treatment (clopidogrel or ticagrelor) or standard treatment with ticagrelor/prasugrel. The composite thrombotic endpoint consisted of cardiovascular death, myocardial infarction (MI), definite stent thrombosis, and stroke at 30 days. The combined bleeding endpoint consisted of Platelet Inhibition and Patient Outcomes (PLATO) major and minor bleeding at 30 days. Univariable and multivariable analyses in addition to a propensity score‐matched (PSM) analysis were conducted.ResultsIn total, 2378 patients, of whom 1033 received GPI and 1345 did not, were included. In multivariable analysis, GPI administration was associated with fewer thrombotic events (hazard ratio [HR] 0.22, 95% confidence interval [CI] 0.09–0.55) and MIs (HR 0.24, 95% CI 0.08–0.73). Furthermore, GPI administration was associated with an increase in bleedings (HR 2.02, 95% CI 1.27–3.19), driven by minor bleedings (HR 2.32, 95% CI 1.43–3.76), without a significant difference in major bleedings (HR 0.69, 95% CI 0.19–2.57). In the PSM analysis, no significant association was found.ConclusionIn STEMI patients undergoing primary PCI, GPI administration was associated with a reduction in thrombotic events at a cost of an increase in (mostly minor) bleedings in multivariable analysis, while propensity score analysis did not show significant associations.
Fluorescent Molecular Logic Gates Driven by Temperature and by Protons in Solution and on Solid
Authors: West Matthew E. S. , Yao Chao‐Yi , Melaugh Gavin , Kawamoto Kyoko , Uchiyama Seiichi , de Silva A. Prasanna 
Published: July 2021

AbstractTemperature‐driven fluorescent NOT logic is demonstrated by exploiting predissociation in a 1,3,5‐trisubstituted Δ2‐pyrazoline on its own and when grafted onto silica microparticles. Related Δ2‐pyrazolines become proton‐driven YES and NOT logic gates on the basis of fluorescent photoinduced electron transfer (PET) switches. Additional PASS 1 and YES+PASS 1 logic gates on silica are also demonstrated within the same family. Beside these small‐molecule systems, a polymeric molecular thermometer based on a benzofurazan‐derivatized N‐isopropylacrylamide copolymer is attached to silica to produce temperature‐driven fluorescent YES logic.