bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ventriculosubgaleal shunting in the treatment of posthemorrhagic hydrocephalus of premature infants: case series
Authors: Canheu Alexandre 
Published: February 2021

Introduction: Posthemorrhagic hydrocephalus(PHH) comprises the most common complication in preterm infants (PTI) who suffered germinative matrix hemorrhage (GMH), and its treatment is still matter of controversies. These infants usually weigh less than 1,500g and a temporary CSF diversion is needed. VSGS is preferred in those cases because it is a simple and rapid method, no need for repetitive aspiration for the evacuation of CSF, gives a permanent decompression without causing electrolyte and nutritional losses, and still protects the cerebral development of newborns with GMH.
Methods: We analyzed a series of 22 PTI who underwent VSGS for PHH, between July 2015 and April 2019, and minimum follow-up 6 months. The median gestation age was 28 weeks (range 23-32). The median weigh was 985g (range 625-1615). The mean period harboring de VSGS was 61,8 days (range 35-80). Results: The cases were studied for: 1) Shunt dependency: 11 children (50%) showed persistent hydrocephalus at further investigation and underwent to VP shunt after stable clinical condition. 2) Infection: 6 subjects (27,2%) showed positive cultures, and were converted to External Ventricular Device (EVD), and further VP shunt; 3) Outcome: the results were separated in Excellent/Good (GOS 5-4) 12 subjects (54%); Poor (GOS 3-2): 8 subjects (36%) and Death (GOS 1): 2 subjects (10%).
Conclusions: VSGS is a good alternative method to treat PHH, especially in a preterm infant who needs a temporary shunt device. The low rate of severe complications and encouraging results about persistent hydrocephalus should guide further investigation and larger cases series.
Endoscopic Management of Intra Ventricular Tumours
Authors: Cinalli Giuseppe 
Published: February 2021

Objective: Neuroendoscopic removal of intraventricular tumors is difficult and time consuming because of the lack of an effective decompression system that can be used through the working channel of the endoscope. The authors report on the utilization of an endoscopic ultrasonic aspirator in the resection of intraventricular tumors.
Methods: Seventeen pediatric patients (14 male, 3 female), ages 1-15 years old, underwent surgery via a purely endoscopic approach using a Gaab rigid endoscope and endoscopic ultrasonic aspirator. Ten patients presented with an intraventricular tumor, three with paraventricular, and 4 with suprasellar lesions. Histology analysis showed 6/17 glial tumors, 3/17 with subependymal giant cell astrocytomas (associated with tuberous sclerosis), two cases presented with intraventricular metastases from high-grade tumors (medulloblastoma, atypical teratoid rhabdoid tumor), 4/17 with suprasellar tumors (2 craniopharyngiomas and 2 optic pathway gliomas), and two with pineal region tumors (1 immature teratoma, 1 PNET). In all patients, the endoscopic trajectory and ventricular access were guided by electromagnetic neuronavigation. Fifteen patients underwent surgery via a precoronal bur hole while supine. In 1 case, surgery was performed through a frontal anterior bur hole and one patient underwent surgery via a posterior parietal approach to the trigone while in a lateral position.
The endoscopic technique consisted of visualization of the tumor, ventricular washing to dilate the ventricles and to control bleeding, obtaining a tumor specimen with biopsy forceps, and ultrasonic aspiration of the tumor. Bleeding was controlled with irrigation, monopolar coagulation, and a thulium laser.
Results/Discussion: In 9 cases, the resection was total or near total (more than 90% of lesion removed). In 8 cases, the resection was partial or biopsy. Histological evaluation of the collected material (withdrawn using biopsy forceps and aspirated with an ultrasonic aspirator) was diagnostic in all cases. The duration of surgery ranged from 30 to 120 minutes. One case was complicated by subdural hygroma requiring a subduro-peritoneal shunt implant. The dry field technique was used in cases with persistence of bleeding.
Conclusion: Patients harboring intraventricular tumors are in most cases ideal candidates for endoscopy biopsy/resection. In this series, endoscopic ultrasonic aspiration proved to be a safe and reliable method for achieving extensive decompression or complete removal in the management of intra- and/or paraventricular lesions in pediatric patients.
Implicaciones del proceso de transformación digital en las instituciones educativas de la Armada del Ecuador
Authors: González Diego Aguirre , Martínez Edison Coba 
Published: February 2021

La capacitación en la transformación digital con una hoja de ruta es un aspecto importante en las instituciones educativas; optimiza el proceso educativo. Este estudio es realizado en las instituciones educativas de la Armada del Ecuador para analizar las implicaciones del proceso de transformación digital sin hoja de ruta. Durante la fase inicial se realizó una investigación exploratoria, luego una correlacional y se construyó un estudio de carácter descriptivo. Se utilizó tanto el método deductivo como el método inductivo, las técnicas para obtener los datos han sido las encuestas y entrevistas a profundidad. La recolección de datos se realizó a través de estas técnicas, a clientes internos y externos, para lo que se seleccionó la muestra apropiada. Los resultados encontrados se generalizaron a la población. Estos evidencian la necesidad de implementar hojas de ruta en las instituciones para garantizar la eficacia del proceso educativo y elevar el nivel de cultura digital. Así se garantiza el desempeño profesional de los egresados.
Exploring speciality preferences and the influencing factors among undergraduate medical students at University of Kufa - Iraq: a questionnaire-based cross-sectional survey
Authors: Amjed Hamid Obaid Al-Jaeed  , Yosif Mohammed Hasan Jawad Al-Rammahi  , Mohammed Albaqer Abbas Baqer Mawash  , Hameed Kareem Shaalan Al-Hadrawy  , Basima Shamkhi Jabbar Al Ghazali  
Published: February 2021

Abstract
Objective: To explore Kufa medical students’ preferences of carrier specialization and to investigate the factors that influence their choice of specialty.
Methods: By using a non-probability convenience sampling technique, a cross-sectional study was performed on (566) medical students from the second-to-sixth-year in University of Kufa, from the 27th of January to the 21st of February 2019 to study the factors that affect the choice of specialties in undergraduate medical students. An anonymous, structured, self-administered questionnaire was handed out to the students and consisted of three sections covering demographic data, the preferred specialty, and the cause behind selecting the specialty. Data analysis was performed using the statistical package for social sciences (SPSS) version 25 for windows.
Results: Cardiology was the most chosen specialty 55 (9.7%) followed by Pediatrics 46 (8.1%) and Dermatology 45 (8.0%). Additionally, 40 (7.1%) students haven’t decided their specialties yet.
The most chosen factors in a descending fashion were "My Passion" which was chosen by 427 (75.4%) students, followed by "income" 67 (11.8%), "less on-call duties" 51 (9.0%), "mentor inspiration" 46 (8.1%), "family member inspiration" 34 (6.0%), "reputation" 22 (3.8%), "less competition" 15 (2.6%), and "number of residency years" 8 (1.4%).
Conclusion: Being passionate about or having a keen interest in the selected speciality were the major influencing factors for students to select their future speciality. However, male students' choices based mainly on the “income” and “reputation” of the field, while females opted to choose “less on call duties” more than males.
Continuous...
Symptoms of hormonal changes in Polish men and women in the second half of life. Andropause and menopause – similarities
and differences
Authors: Jarecka Karolina 
Published: January 2021

IntroductionHormonal changes occur in aging men and women. Considering andropausal changes as similar to menopause, however, is still an open topic. The aim of the research was to assess the occurrence and severity of symptoms associated with hormonal changes in men and women and to find similarities between the male and female climacterium.Material and methods397 individuals (197 men and 200 women) aged 45 to 68 years were examined. The subjects were divided into three groups, with regards to: risk of symptoms, transition period, and andropause/menopause. A sociodemographic survey, the Self-assessment Test, recommended by the pharmaceutical company Organon for the assessment of androgen deficiency in men, and the Women’s Health Questionnaire to measure symptoms considered menopausal were used in the research.ResultsThe research results showed that menopause-specific symptoms – psychological, vasomotor and sexual – are considered criterial for andropause. However, women experience a greater spectrum of symptoms associated with hormonal changes than men. An analysis of all the symptoms showed that most of them are clearly visible in the oldest group of men and much earlier in women – during the menopausal period.ConclusionsThe symptoms observed in men and women in middle and late adulthood are considered to be characteristic of hormonal changes associated with andropause and menopause. However, due to their different scope, dynamics and consequences, the processes in question remain ambiguous.
Computed tomography-guided percutaneous radiofrequency and laser ablation for the treatment of osteoid osteoma – long-term follow-up from 5 to 10 years
Authors: Lorenc Tomasz , Kocoń Hanna , Gołębiowski Marek 
Published: January 2021

IntroductionThe impact of computed tomography (CT)-guided, percutaneous radiofrequency ablation and interstitial laser ablation (ILA) on the management of patients with osteoid osteoma was studied. This was carried out by assessing immediate and long-term clinical outcomes, the complication rate, and repeat therapy effectiveness in recurrent patients who have already experienced percutaneous ablation.Material and methodsConsecutive patients with osteoid osteoma were assessed before the interventional treatment in a single centre from 2010 to 2015. Patient demographics, complications, and recurrence were recorded. The pain was evaluated with Visual Analogue Scale (VAS). Percutaneous procedures were performed by means of radiofrequency thermoablation or ILA. Epidural or regional anaesthesia in the CT suite was applied in all procedures. Success, whether primary or secondary, was measured as complete pain relief without evidence of recurrence after the first or second procedure, respectively. Osteoid osteoma characteristics, procedure overview, and technical success were looked for in pre-procedural and procedural scans.ResultsEighty-three per cent of osteoid osteomas were located in lower extremities, 56% of tumours were intracortical, and 83% of osteoid osteomas were extra-articular. The mean pre-procedure VAS score was 8.5 ± 0.8, while the overall primary success rate of radiofrequency thermoablation and ILA was 87.5%. No major complications were noted. The mean follow-up period for patients in was 7.5 years (5.0-10.2 years).ConclusionsPercutaneous, CT-guided thermoablation proved to be effective and should become the method of choice in osteoid osteoma treatment because of its minimal invasiveness. Our results show that there is no risk of very late recurrence after achieving primary and secondary treatment success.
Measurement of the radiation level dose to patient from fluoroscopy device during cardiac catheterization
Authors: Joudha Luma Naji 
Published: February 2021

Fluoroscopy is a type of medical imaging that shows a continuous X-ray image on a screen, it is used in a wide range of examination and procedures for diagnosis such as in cardiac catheterization. Fluoroscopy can result in relatively high radiation doses, especially for complex interventional procedures that it needed to monitor radiation to reduce exposure. The purpose of this study is to determine the radiation doses for patients during cardiac catheterization exam and compare it with the permissible dose limits. The main parameters which are studied in this work are the time of exposure dose rate, x-ray techniques (milliamper. second), tube voltage (kilovolt) and Dose Area Product (DAP). Twenty-seven patients were included and absorbed doses were measured and distributed according to Fluoroscopy (Fluo) time, mAs and Dose Area Product (DPA). It was found that the absorbed dose received by the patients has a linear relationship with the Fluoroscopy time, mAs and DAP. Exposure dose rates were measured and compared with the maximum permissible dose (100 mGy/min), the estimated patient dose rate varied from (12-81.6) mGy/min) for 24 patients as a permissible dose in the safe side, and 3 patients exposed to higher values of the exposure dose rates ) over permissible dose) range (107.4-108) mGy/min
Detection of opioid growth factor in Multiple Sclerosis Patients
Authors: Taha Khamael Abdulla , Iqbal Mayada N. , Shalal Gheyath Abd Ali 
Published: February 2021

Multiple sclerosis (MS) is a recent prevalent central nervous system disease that affects the brain and spinal cord. It is assumed that it is an intermediate immune disorder in the central nervous system and is complex with incomplete etiology. Some research have confirmed that the Opioid growth factor(OGF), which was called chemically Enkephalin [Met5], is considered as a biomarker for the onset of MS. The purpose of this study was to look into the biomarker level of OGF and its correlation with body mass index(BMI) among patients with MS. A total number of 100 patients were diagnosed in two groups (54 early diagnosis of MS without treatment, 46 early diagnosis with treatment) according to McDonald criteria and 50 healthy control groups were included. All demographic data of the study samples were recorded (age, gender), as well as clinical data such as (BMI),and level OGF(serum and saliva) estimated by ELISA method. The current study revealed that the mean+SD of serum OGF in patients with multiple sclerosis for both groups(947.167 ± 134.262 ng/ml) was less concentrated than the control group (1046.642 ± 63.605 ng/ml) with a very large difference (P <0.01). While the mean concentration of OGF in saliva was (960.158 ± 91.684 ng/ml) for patients with multiple sclerosis (early diagnosis group without treatment and the treatment group), its concentration was higher than the control group (880.059 ± 87.700 ng/ml) with a large statistical significance (P <0.01). The current study showed an important correlation between the body mass index and serum OGF level at (p = 0.022) in the early diagnosis group for multiple sclerosis patients with treatment, , while in the early diagnosis group for multiple sclerosis patients without treatment, a very significant association was found between BMI and serum OGF level at (p = 0.009). Interestingly, the current study showed that saliva biomarker (OGF) would be a good predictor for diagnosing MS.
KARAKTERISTIKEKSTRAK AIR DAUN PUGUNTANO [Curanga fel-terrae (Lour.) Merr.] YANG BERPOTENSI SEBAGAI ANTELMINTIK
Authors: Patilaya Popi , Husori Dadang Irfan 
Published: January 2021

OBJECTIVE: This study aimed to determine the characteristics of the water extract of leaves puguntano (Curanga fel-terrae (Lour.) Merr.) Using spectroscopic methods and phytochemical screening.METHODOLOGY: phytochemical screening performed to analyze compounds alkaloids, flavonoids, glycosides, anthraquinone glycosides, saponins, tannins, cyanogenic glycosides, and triterpenoids / steroids. Analyses were performed using FTIR spectrophotometer (Shimadzu) with IR Solution software. The wavelength is set at 4000 – 400 cm-1 with a resolution of 4 cm-1 and 16 scanner.RESULTS: Puguntano leaf water extract contains flavonoids, glycosides, saponins, tannins, steroids, and terpenoids. Infrared spectrum of puguntano leaf aqueous extract showed a O – H fuctional group at 3313.71 cm-1, C – H at 2974.23 and 2881.65 cm-1, C = C at 1689.65 and 1597.06 cm-1, C – O at 1265.30 and 1076.28 cm-1 and group C – H aromatics at 813.96 cm-1 in the fingerprint region
UJI AKTIVITAS EKSTRAK ETANOL DAUN ALPUKAT (Persea americana Mill.) TERHADAP PENYEMBUHAN LUKA BAKAR PADA PUNGGUNG MENCIT PUTIH JANTAN (Mus musculus)
Authors: Sentat Triswanto , Permatasari Rizki 
Published: January 2021

Activity Assay of avocado leaf (Persea americana Mill.) ethanol extract on burn healing at back skin of white male mice (Mus musculus) aims to determine the best concentration of avocado leaf ethanol extract to healing burn on back skin of mice. Extract of avocado leaf obtained by maceration method using ethanol 70%. Burn made by soldering iron modified with square plate (size 1 x 1 cm2), during 2 seconds contact at the skin and make the skin formed blister. Observation of the burn area was doing daily for 14 days, and also the treatment with the 3 concentrations extract variation (20%,35%, and 50%), negative control and positive control. Result of research show that all avocado leaf ethanol extract in concentrations 20%, 35% and 50% have good activity in burn healing, from first day until 14th day they showed percentage of burn recovering successively equal to 86%, 88% and 90%. Negative control showed that process healing of burn was very tardy, only has percentage of burn recovering equal to 32,67% on 14th day, while positive control showed 100% burn healing on 11st day. The best concentration of avocado leaf ethanol extract on healing burn is 50% with 90% burn healing
UJI EFEKTIVITAS ANTHELMINTIK EKSTRAK RIMPANG BANGLE (Zingiber purpureum Roxb.) TERHADAP CACING Ascaridia galli SECARA IN VITRO
Authors: Susanti Yanthi , Astuti Indri , Astuti Ade Ari Dwi 
Published: January 2021

The research was conducted to observe anthelmintic efficacy on rhizome extract bangle against Ascaridia galli by in vitro procedure. Experimental study was conducted, with samples rhizomes bangle powder and maceration method in three concentrations of 2%, 4% and 8%. The experimental animals used is Ascaridia galli with NaCl 0.9% as negative control and a pyrantel pamoate suspension as positive control with concentrations of 0.2%, 0.4% and 0.6%. The study was conducted in July 2014 at the Laboratory on IKIFA Academy of Pharmacy. The data analysis used is a probit analysis. Results of Research was rhizome extract bangle (Zingiber purpureum Roxb.) having as anthelmintic efficacy against Ascaridia galli with LC50 2.29% and LT50 in 4 hours 3 minutes 18 seconds
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN GANGGUAN FUNGSI PARU PADA PEKERJA PEMBUAT KASUR (STUDI KASUS DI DESA BANJARKERTA KARANGANYAR PURBALINGGA)
Authors: Yuliawati Ratna 
Published: January 2021

Mattress maker is one of the high-risk job of lung function. Dust from the production of an effect on lung function. Research describe dust from production assosiated to the pulmonary dysfunction. Previous studies explain the illness rate reached 70% in workers who inhale cotton dust. Describe the various factors assosiated to the pulmonary dysfunction between age, nutritional status, years of service, the use of masks, ventilation, workplace ownership, and the amount of dust inhaled by the incidence of lung function, job characteristics, and the amount of dust inhaled by the mattress makers in the District Karanganyar Purbalingga. This study was an cross-sectional, with a total sample of 80 workers mattress maker. The independent variable in this study is a age, nutritional status, years of service, the use of masks, ventilation, workplace ownership, and levels of total particles inhaled. The analysis was performed using univariate, bivariate and multivariate as well as by calculating the ratio of prevalence. The results showed that there are 4 variables significantly associated with lung function. that workers exposed to dust> 0.2 mg/m3 per day with a ratio of 27.203 prevalent (95% CI = 1.885 to 39,257) Working period (≥ 10 years), with a ratio of 21,502 prevalent (95% CI = 9.559 to 483,65) The use of masks (not always use) with the ratio of 43.965 prevalent (95% CI = 2.831 to 682,80) Ownership separate workplaces with 27.583 prevalent ratio (95% CI = 1.955 to 389,25). The risk factors significantly associated with impaired lung function is inhaled dust particles, years of service, the use of masks and a separate work between sections. suggested to the labor department and the health department to conduct promotive and preventive so that workers can be maintained mattress maker of health and safety work
ANALISIS KUALITATIF FORMALIN PADA TAHU MENTAH YANG DIJUAL DI PASAR KALINDO, TELUK TIRAM DAN TELAWANG BANJARMASIN
Authors: Ariani Novia , Safutri Maida , Musiam Siska 
Published: January 2021

Tofu is one of favourite food in Indonesia because it is containing the nutrients which body needs, such as protein. Tofu comes from processed soybeans and contains high water, so it can only save for 1 or 2 days in storage. Because of that reason several manufacturers or dealers add additional ingredients, one of them was formaldehyde to made tofu were durable to be restored and increases consumer appeal. The aim of the study was to identifity the contain of formaldehyde at crude tofu in Kalindo, Teluk Tiram and Telawang market Banjarmasin. The investigated sample was white crude tofu were 19 samples obtained with accidental sampling. The type of research was descriptive research. Qualitative analysis of formaldehyde at crude tofu was done with conventional method by using Ag(NH3)2NO3 and KMnO4 0,1N reagents. The result of study shows that crude tofu was sold in Kalindo market 90% (9 of 10 samples) positive contain formaldehyde, 100% (4 of 4 samples) at Teluk Tiram market positive contain formaldehyde and 80% (4 of 5 samples) at Telawang market positive contain formaldehyde
INVENTARISASI DAN IDENTIFIKASI TUMBUHAN OBAT SUB ETNIS KUTAI DESA GENTING TANAH KECAMATAN KEMBANG JANGGUT KABUPATEN KUTAI KARTANEGARA KALIMANTAN TIMUR
Authors: Apriliana Anita , Hendra Medi , Sapitri Atila 
Published: January 2021

Indonesia has rich tropical forests will be diverse plants that can be used as a traditional medicine, ranging from roots, stems, leaves, until all fruit is of great value and can be used as a medicine for the health as well as from different tribe who were in Indonesia. Since old time sub etnic Kutai using different types of plants as a medicine because the lack of medical personnel and health care center in curing diseases. This study aims to find out the types of medicinal herbs used by tribes. The results there were 39 Medicinal plants used by tribes that is Serai, Sirih, Tumbuh daging, Kepius, Patah tulang, Kunyit root, Senuru , Mali wood, Prepat wood, lupun root, Kecubung, Terung pipit, Gelinggang, Beribit grass, Syurga leaf, Tapis bongol, Nyiur ongo, Singgah bini wood, Penggel habeng, Serkemudi grass, Tunjuk langit root, Kemet hitam, Pacar beleng, penggel putih, Ketotol grass, Kemantrah, Sahung wood, Tajerebo, Cula adem, Risip leaf, Lalang, Sampai root, Cancut haji jewa, Mersesat leaf, Lekop leaf, Kuku tupai, Kempis root, Kemet putih and Kedeme