bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interventions to increase personal protective behaviours to limit the spread of respiratory viruses: A rapid evidence review and meta-analysis
Authors: Perski Olga , Szinay Dorothy , Corker Elizabeth , Shahab Lion , West Robert , Michie Susan 
Published: May 2021

PURPOSE: Increasing personal protective behaviours is critical for stopping the spread of respiratory viruses, including SARS-CoV-2: we need evidence to inform how to achieve this. We aimed to synthesise evidence on interventions to increase six personal protective behaviours (e.g. hand hygiene, face mask use) to limit the spread of respiratory viruses.

METHODS: We used best practice for rapid evidence reviews. We searched Ovid MEDLINE and Scopus. Studies conducted in adults or children with active or passive comparators were included. We extracted data from published intervention descriptions on study design, intervention content, delivery mode, population, setting, mechanism(s) of action, acceptability, practicability, effectiveness, affordability, spill-over effects and equity impact. Study quality was assessed with Cochrane’s risk of bias tool. A narrative synthesis and random-effects meta-analyses were conducted.

RESULTS: We identified 39 studies conducted across 15 countries. Interventions targeted hand hygiene (n=30) and/or face mask use (n=12) and used two- or three-arm study designs with passive comparators. Interventions were typically delivered face-to-face and included a median of three behaviour change techniques. The quality of included studies was low. Interventions to increase hand hygiene (k=6) had a medium, positive effect (_d_=0.62, 95% CI=0.43-0.80, _p_<.001, I2=81.2%). Interventions targeting face mask use (k=4) had mixed results, with an imprecise pooled estimate (OR=4.14, 95% CI=1.24-13.79, _p_<.001, I2=89.67%). Between-study heterogeneity was high.

CONCLUSIONS: We found low-quality evidence for positive effects of hand hygiene interventions, with unclear results for face mask use interventions. There was a lack of evidence for interventions targeting most behaviours of interest within this review.
Preparing and Storing an Emergency Safe Drinking Water Supply
Authors: Shukla Shuchi , Obreza Thomas 
Published: May 2021

The purpose of this fact sheet is to emphasize the importance of having a personal safe drinking water supply during an emergency, and to describe the steps that Florida's citizens should take to prepare and store drinking water. This document is SL220, a fact sheet of the Soil and Water Science Department, Florida Cooperative Extension Service, Institute of Food and Agricultural Sciences, University of Florida. Original publication date: October 2004.
SL220/SS439: Preparing and Storing an Emergency Safe Drinking Water Supply (ufl.edu)
Analisis Penyebab Tundaan dan Panjang Antrian Kendaraan Pada Pergerakan U-Turn di Ruas Jalan Perkotaan Kota Balikpapan
Authors: Ariyanto Muhammad Najib 
Published: May 2021

AbstractCongestion is a problem in transportation that most occurs on urban roads. The increase in the number of vehicle that are not matched by an increase in road capacity makes the volume of vehicle that cross the road exceeds the existing road capacity causing congestion. Besides increasing the number of vehicle, one of the causes of congestion was the existence of U-Turns. The poor design and management of U-Turns will cause drivers to be disorganized when turn around and causing congestion. Factors that cause congestion on the U-Turns include delay and length of queue. This research was conducted with multiple linear regression methods with data in the form of traffic surveys and road geometry. The results of multiple linear regression analysis mentioned that the vehicle delay time on the U-Turn movement was caused by the turning volume and the median aperture width with the dominant factor is the median aperture width. Then, the length of queue on the U-Turn movement is caused by the delay time and the turning time with the dominant factor is the turning time. Keywords : congestion, length of queue, delay time, U-Turn AbstrakKemacetan merupakan suatu permasalahan dalam transportasi yang sering terjadi di jalan perkotaan. Peningkatan jumlah kendaraan yang tidak diimbangi dengan peningkatan kapasitas jalan membuat volume kendaraan yang melintasi ruas jalan tersebut melebihi kapasitas jalan yang ada sehingga menyebabkan kemacetan. Selain peningkatan jumlah kendaraan, salah satu penyebab kemacetan adalah adanya U-Turn. Desain dan pengelolaan U-Turn yang kurang baik akan menyebabkan tidak teraturnya pengendara yang akan memutar arah sehingga menimbulkan kemacetan. Faktor yang menyebabkan kemacetan pada U-Turn diantaranya adalah tundaan dan panjang antrian. Penelitian ini dilakukan dengan metode analisis regresi linier berganda dengan data berupa survei lalu lintas dan geometrik jalan. Hasil analisis regresi linier berganda menyebutkan bahwa waktu Tundaan kendaraan pada pergerakan U-Turn dipengaruhi oleh adanya Volume Putar Balik kendaraan dan Lebar Bukaan Median dengan faktor dominan berupa Lebar Bukaan Median. Kemudian Panjang Antrian pada pergerakan U-Turn dipengaruhi oleh waktu Tundaan dan Waktu Putar Balik dengan faktor dominan berupa waktu Putar Balik. Kata Kunci: kemacetan, panjang antrian, tundaan, U-Turn.
Pemanfaatan Solar Cell Sebagai Sumber Energi Listrik Hydroponic Drip System
Authors: Huwaida Nabila 
Published: May 2021

Pembangunan hydroponic drip system belum sepenuhnya sesuai dengan kualitas yang diinginkan. Faktor yang mempengaruhi pada tanaman hidroponik yaitu perubahan pH air, part per million (ppm), suhu air serta listrik yang tidak terkontrol sehingga memperburuk kualitas dan kuantitas pada tanaman hidroponik. Oleh karena itu, pemanfaatan solar cell sebagai sumber utama hydroponic drip system sangat efektif sebagai pengganti penggunaan listrik dari sistem ini, karena dapat mengurangi biaya penggunaan listrik dengan menggunakan media baterai sebagai penyimpanan daya yang dihasilkan. Selain menggunakan solar cell sebagai sumber listrik, sistem ini juga dilengkapi dengan power supply dari jala-jala sebagai cadangan sumber energi listrik apabila kapasitas baterai akan habis maupun kurang dari tegangan minimal kerja baterai sebesar 11,5 V. Pengujian solar cell dilakukan menghadap arah utara, dikarenakan posisi tempat pengujian berada di selatan garis khatulistiwa. Waktu pengujian dilaksanakan pada pukul 10.00 WIB – 14.50 WIB dengan sudut kemiringan yang diuji sebesar 0°, 10°, 20°, 30° dan 40°. Data menunjukkan perolehan sudut kemiringan solar cell yang optimal sebesar 30°, hal ini disebabkan karenai posisi solar cell pada sudut kemiringan ini lebih maksimal dalam menyerap intensitas cahaya.
Phenotypic characterization and production potentials of exotic goat breeds and their crosses in Rajshahi metropolitan area of Bangladesh
Authors: Ahmed EM , Amin MR , Basrin R , Bhuiyan MSA 
Published: May 2021

This study was conducted to investigate the morphology, morphometry and production performances of exotic goat breeds and their crossbreds available at Boalia, Shahmokhdum, Rajpara and Matihar thana under Rajshahi metropolitan city. A total of 73 animals’ information was collected from 39 exotic goat flock owners using a semi-structured questionnaire through interviewing of farmers, visual observation and on-spot measurement of the animals. Exotic goat breeds and their crosses were found predominantly higher (>93%) in Rajshahi Metropolitan areas where less than 7% Black Bengal goats were identified. In most cases, deviation of breed specific coat color due to crossing between different types of crossbreds among the populations was noted. The genotype frequencies of Beetal, Kalahari, Sirohi, Jamunapari, Anglo Nubian and their crossbreds and Black Bengal goats were found to be 50.68, 15.07, 13.70, 8.22, 8.22 and 4.11%, respectively. The average mature live weight (12 to 18 months) of those corresponding exotic genotypes in male and female respectively were found 46.88±5.66, 56.07±8.03, 32.67±8.09, 59.54±7.96 and 64.06±4.67 kg, and 21.70±2.24, 22.41±3.64, 17.37±4.05, 24.5±0.5 and 27.47±6.85 kg. Irrespective of genotypes, the mean age at puberty, lactation length, litter size, kidding interval and days open were found 167.50±3.49 days, 76.61±4.90 days, 1.71±0.10, 224.44±5.56 days and 52.64 ± 2.30 days, respectively. However, none of the aforementioned traits differed significantly (P>0.05) among the five different exotic genotypes. In conclusion, this study provides some basic information on the performances of exotic goat breeds or their crossbreds at Metropolitan areas under intensive management conditions which could be utilized for designing proper breeding plan in their conservation and simultaneous improvement.
Bang. J. Anim. Sci. 2020. 49 (2): 100-107
Effect of feeding Tephrosia bracteolate on the bioavailability of macro minerals in goat
Authors: Ogungbesan AM , Adeleke GA , Fasina OE , Fajemisin AN 
Published: May 2021

Sixteen West African Dwarf Goats (8 bucks and 8 does) were balanced for age, sex and weight (average of 5.79±0.60 kg), to evaluate the effect of Tephrosia bracteolata (Tb) on macro mineral utilization. To examine the effect of Tephrosia bracteolata (Tb), different levels of Tb were used (Tb20, Tb40, Tb60 and Tb80). Ca absorbed (gm) ranged from 0.64 (Tb20) to 1.57 (Tb80) and Ca retention was from 0.62 (Tb20) to 1.56 (Tb80) which was partially linear. In both absorption and retention of Ca, Tb20 and Tb80 found the lowest (P<0.05) and the highest (P<0.05) value respectively. Like Ca, P also followed the same trend in case of retention and absorption as well. Concerning Mg, the lowest (0.41, 0.40) and the highest (0.67, 0.65) absorbed and retained value (g/day) was observed in Tb 20 and Tb 80 respectively. Tb80 showed significantly higher Na absorption than Tb20. In case of Na retention, Tb80 showed the highest (P<0.05) retention than other groups. In K absorption (g/day), increasing trends (P<0.05) were observed from Tb20 (0.44) to Tb80 (1.25). In case of retention, Tb80 found the highest (P<0.05) K retention than other groups. These positive balances of minerals result linearly appreciating with the increase of T. bracteolata in the diets which might be due to leguminous properties in T. bracteolata. T. bracteolata can be used as a roughage source for goats without any remarkable adverse or, side or ill effects which affect the well-being of animals feeding.
Bang. J. Anim. Sci. 2020. 49 (2): 119-127
Use of Spirulina platensis in place of vitamin mineral premix on the performance of broiler
Authors: Islam KMS , Roy P , Debi MR , Kamruzzaman M 
Published: May 2021

The experiment was conducted to compare the effects of different sources of Spirulina and vitamin mineral premix as feed additive on the growth performance of broiler. Two hundred day old broiler chicks (COBB-500) were divided into five groups such as T1-(Feed containing 0.30% Vitamin mineral premix+0.0% Spirulina), T2-(Feed containing 0.15% Vitamin mineral premix+0.15% Spirulina from China), T3-(Feed containing 0.0% Vitamin mineral premix+0.30% Spirulina from China), T4-(Feed containing 0.15% Vitamin mineral premix+0.15% Spirulina from Myanmar) and T5-(Feed containing 0.0% Vitamin mineral premix+0.30% Spirulina from Myanmar) having four replication in each group containing 10 birds/replication. The experiment was conducted for 28 days (Completely Randomized Design) with ad libitum feed and water. Live weight was numerically higher (P>0.05) in T4 in 4th weeks of age. Lower feed intake observed in T3 and T5 which was mainly 50% replacement of vitamin mineral premix by Spirulina. After end of the feeding trial feed conversion ratio (1.66) in control group was higher (P<0.05) than other groups (1.63, 1.64, 1.59 and 1.61 respectively in T2, T3, T4 and T5). Dressing percentage (63.12%), breast weight (21.22%) and thigh weight (8.54%) were higher (P<0.05) in T4 than all other groups. Concentration of total cholesterol in blood plasma (64.42mg/dl) and serum albumin (1.75g/dl) was lower (P<0.05) in T4. It could be concluded that Spirulina from Myanmar is better than China and 50% synthetic vitamin mineral premix could be replaced by using Spirulina from Myanmar for better growth of broiler.
Bang. J. Anim. Sci. 2020. 49 (2): 151-158
Effect of Different Forms of Periodic Piecewise Linear Forces on Duffing Oscillator
Authors: Priyatharsini S. V. , Bhuvaneshwari B. , Chinnathambi V. , Rajasekar S. 
Published: May 2021

The paper highlights the effect of different forms of periodic piecewise linear forces in the ubiquitous Duffing oscillator equation. The external periodic piecewise linear forces considered are Triangular, Hat, Trapezium, Quadratic and Rectangular. With the aid of some numerical simulation tools such as bifurcation diagram, phase portrait and Poincare´ map, the different routes to chaos and various strange attractors are found to occur due to the applied forces. The effect of an ε-parametric control force in the Duffing system is also analyzed. To characterize the regular and chaotic behaviours of this system, the maximal Lyapunov exponent is employed.
EFEKTIVITAS PEMBELAJARAN ONLINE VERSUS TATAP MUKA
Authors: Nurlatifah Nurlatifah , Ahman Eeng , Machmud Amir , Sobandi A 
Published: May 2021

Penelitian ini dilatar belakangi oleh rendahnya hasil belajar siswa di Indonesia khususnya Kabupaten Cianjur. Hal ini ditunjukan dengan hasil Ujian Tengah Semester (UTS). Penelitian ini bertujuan untuk menganalisis efektivitas pembelajaran online dan tatap muka pada mata pelajaran ekonomi yang memiliki karakteristik yang sama (guru, waktu belajar dan penilaian akhir). Metode yang digunakan dalam penelitian ini adalah survei. Adapun teknik pengumpulan data menyebar kuesioner secara online melalui Google-Form. Populasi dalam penelitian ini siswa Madrasah Aliyah Swasta Bojongjati yang berjumlah 160 siswa dengan sample 110 siswa dengan teknik pengambilan sampel secara random sampling. Tingkat efektivitas diukur melalui satu indikator objektif yaitu nilai UTS dan tiga indikator subjektif (kahadiran, keaktifan dan kepuasan). Hasil penelitian ini menunjukan bahwa pembelajaran online kurang efektif daripada pembelajaran tatap muka (face to face).
The Associations Between Problematic Internet Use, Healthy Lifestyle Behaviors and Health Complaints in Adolescents
Authors: Klavina Aija , Veliks Viktors , Zusa-Rodke Anna , Porozovs Juris , Aniscenko Aleksandrs , Bebrisa-Fedotova Luize 
Published: May 2021

This study aimed to explore relationship between problematic internet use (PIU), healthy lifestyle behaviors and subjective health complaints.Methods: Participants (396 adolescents, aged 11–18 years) from 34 general education schools across Latvia completed online survey. The PIU was assessed by the Problematic and Risky Internet Use Screening Scale (PRIUSS) collecting data on social impairment, emotional impairment, and risky/impulsive internet use. The subjective health complaints assessed were somatic and psychological symptoms. Healthy lifestyle behaviors assessed were daily physical activities, time spent in using information technologies (IT), eating habits, and duration of sleep.Results: This study found that 31.00% (n = 124) of the participants scored at risk for PIU. Correlates associated with PIU were subjective health complaints, low physical activity, lack of meals together with family and disturbed sleeping regimes on weekends (P &lt; 0.001). Stepwise multiple regression analyses showed that 34% of the variance in the PRIUSS scores was explained by psychological health complaints (irritability, depression, and nervousness), screen time use on weekends, physical activity, drinking sweetened soft drinks and unhealthy eating habits.Conclusion: PIU behaviors among adolescents in Latvia are associated with psychological symptoms and unhealthy lifestyle. Further effective measures and interventions are needed to prevent development of psychosomatic health problems.
Erectile Dysfunction Is Associated With Excessive Growth Hormone Levels in Male Patients With Acromegaly
Authors: Chen Zhengyuan , Shao Xiaoqing , He Min , Shen Ming , Gong Wei , Wang Meng , Zhang Yichao , Liu Wenjuan , Ma Zengyi , Ye Zhao , Lu Yongning , Yang Nianqin , Chen Shanwen , Hu Lydia , Li Yiming , Wang Yongfei , Zhao Yao , Zhang Zhaoyun 
Published: May 2021

ObjectiveTo determine the risk factors for erectile dysfunction (ED) in male patients with acromegaly and to prospectively investigate the short-term changes of erectile function after surgery or medical treatment.MethodsSixty-three male patients were subjected to nocturnal penile tumescence and rigidity (NPTR) test for the evaluation of erectile function. The measurement of serum nitric oxide (NO) was also performed. Twenty-seven patients were re-evaluated by NPTR after surgery or long-term somatostatin analogues (SSA) treatment.ResultsTwenty-two patients (34.9%) had ED. Patients with ED showed higher random GH (17.89 [10.97-44.19] μg/L vs 11.63 [4.31-28.80] μg/L, p = 0.020) and GH nadir (GHn) (10.80 [6.69-38.30] μg/L vs 8.76 [3.62-18.19] μg/L, p = 0.044) during oral glucose tolerance test (OGTT). The NO levels of ED patients were lower than non-ED patients (9.15 [5.58-22.48] μmol/L vs 16.50 [12.33-31.78] μmol/L, p = 0.012). After treatment, patients who present improvement in erectile function showed lower post-GHn (0.07 [0.03-0.12] ng/ml vs 1.32 [0.09-3.60] ng/ml, p = 0.048) and post-IGF-1 index (1.03 ± 0.38 vs 1.66 ± 0.95, p = 0.049). The multivariate analysis indicated post-GHn was still associated with the improvement of erectile function after correction of other covariates (OR: 0.059, 95% CI: 0.003-1.043, p = 0.053).ConclusionsExcessive GH is related to ED in male patients with acromegaly. GH normalization after treatment is beneficial for short-term erectile function recovery.
Cancer Susceptibility Candidate 9 (CASC9) Promotes Colorectal Cancer Carcinogenesis via mTOR-Dependent Autophagy and Epithelial–Mesenchymal Transition Pathways
Authors: Islam Khan Md Zahirul , Law Helen Ka Wai 
Published: May 2021

BackgroundColorectal cancer (CRC) is the third most common cancer worldwide. Many recent studies have demonstrated that different long non-coding RNAs (lncRNAs) are involved in the initiation, advancement, and metastasis of many cancers including CRC. Cancer susceptibility candidate 9 (CASC9) is an lncRNA that has been reported in many cancers, but its role in CRC is poorly understood. In this study, we aimed to examine the expression of CASC9 in CRC cell lines and to determine the mechanism of action of CASC9 in CRC carcinogenesis.MethodsThe expression of CASC9 in CRC tissues was compared with normal samples from publicly available datasets in The Cancer Genome Atlas (TCGA) and The Encyclopedia of RNA Interactomes (ENCORI). CASC9 expression was further verified in four CRC cell lines (DLD1, HT-29, SW480, and HCT-116) and normal colorectal cell line (CCD-112CoN) by real-time quantitative polymerase chain reaction (RT-qPCR). After gene silencing in HCT-116 and SW480, Cell Counting Kit-8 assay, clonogenic assay, and wound healing assay were performed to evaluate cell proliferation, viability, and migration index of cells. Western blotting was used to explore the key pathways involved.ResultsCASC9 was significantly upregulated as analyzed from both public datasets TCGA and ENCORI where its overexpression was associated with poor survival of CRC patients. Similarly, CASC9 was significantly overexpressed in the CRC cell lines compared with normal cells studied. The silencing of CASC9 in HCT-116 and SW480 attenuated cell proliferation and migration significantly. Furthermore, pathways investigations showed that silencing of CASC9 significantly induced autophagy, promoted AMP-activated protein kinase (AMPK) phosphorylation, inhibited mTOR and AKT signaling pathways, and altered epithelial–mesenchymal transition (EMT) marker protein expression.ConclusionWe demonstrated that silencing of CASC9 contributes to the reduced CRC cell proliferation and migration by regulating autophagy and AKT/mTOR/EMT signaling. Therefore, CASC9 plays an important role in carcinogenesis, and its expression may act as a prognostic biomarker and a potential therapeutic target of CRC management.
Efficacy of Low-Dose Rituximab on Neuromyelitis Optica-Associated Optic Neuritis
Authors: Zhao Shuo , Zhou Huanfen , Xu Quangang , Dai Hong , Wei Shihui 
Published: May 2021

Purpose: To prospectively investigate the efficacy and tolerance of low-dose rituximab (RTX) for the treatment of neuromyelitis optica-associated optic neuritis (NMO-ON).Methods: Optic Neuritis patients with seropositive aquaporin 4-antibody (AQP4-Ab) were diagnosed with NMO-ON and recruited for treatment with low-dose RTX (100 mg * 4 infusions) and were then followed monthly for a minimum of 3 months. Reinfusion of 100 mg RTX was given when the CD19+ B lymphocyte frequency was elevated to above 1%. The serum AQP4-Ab level was tested by an enzyme-linked immunosorbent assay (ELISA).Results: A total of 43 NMO-ON patients (1 male/42 female, 75 involved eyes) were included in this study. CD19+ B cell clearance in the peripheral blood was induced in 97.7% of patients after induction treatment. A significant decrease in serum AQP4-Ab concentration was observed after induction treatment (P = 0.0123). The maintenance time of B cell clearance was 5.2 ± 2.25 months. The relapse-free rate was 92.3% in patients followed-up for over 12 months, and patients with non-organ-specific autoimmune antibodies tended to relapse within 6 months. A total of 96.2% of patients had stable or improved vision, and a decrease in the average expanded disability status scale (EDSS) score was found. Structural alterations revealed by optic coherence tomography were observed in both ON and unaffected eyes. The rates of infusion-related reactions and long-term adverse events (AEs) were 18.6 and 23.1%, respectively. No severe AEs was observed.Conclusions: Low-dose rituximab is efficient and well-tolerated in treating NMO-ON.
Serum Adalimumab Levels After Induction Are Associated With Long-Term Remission in Children With Inflammatory Bowel Disease
Authors: Lucafò Marianna , Curci Debora , Bramuzzo Matteo , Alvisi Patrizia , Martelossi Stefano , Silvestri Tania , Guastalla Veronica , Labriola Flavio , Stocco Gabriele , Decorti Giuliana 
Published: May 2021

Introduction: Adalimumab is effective in inducing and maintaining remission in children with inflammatory bowel diseases (IBD). Therapeutic drug monitoring is an important strategy to maximize the response rates, but data on the association of serum adalimumab levels are lacking. This study aimed to assess the association of adalimumab concentrations at the end of induction and early during maintenance for long-term response.Materials and Methods: Serum samples for adalimumab level measurement were collected during routine visits between adalimumab administrations and therefore not necessarily at trough, both during the induction (week 4 ± 4) and maintenance phases (week 22 ± 4, 52 ± 4, and 82 ± 4). Adalimumab and anti-adalimumab antibodies were measured retrospectively using enzyme-linked immunosorbent assays (ELISA). Disease activity was determined by Pediatric Crohn's Disease Activity Index or Pediatric Ulcerative Colitis Activity Index.Results: Thirty-two children (median age 14.9 years) were enrolled. Sixteen, 15, 14, and 12 patients were in remission at weeks 4, 22, 52, and 82, respectively. Median adalimumab concentration was higher at all time points in patients achieving sustained clinical remission. Adalimumab levels correlated with clinical and biochemical variables. Adalimumab concentration above 13.85 and 7.54 μg/ml at weeks 4 and 22 was associated with remission at weeks 52 and 82.Conclusions: Adalimumab non-trough levels are associated with long-term response in pediatric patients with IBD.