bluuebunny/crossref_metadata_2025_split huggingface dataset:
Awareness, Knowledge, and Treatment Patterns of Nonmetastatic Inflammatory Breast Cancer in Low- and Middle-Income Countries: The BRIDGES Study
Authors: Schlam Ilana , Hirko Kelly A. , Shveid Daniela , Abuali Inas , Sewaralthahab Sarah , Nakhils Faina , Hazra Aditi , Lengyel Csongor , Altuna Sara , Hussain Sadaqat , Seid Fahmi , Jamil Sara , Odhiambo Andrew , Leone Jose Pablo , Metzger Otto , Abraham Jame , Soto-Perez-de-Celis Enrique , Chen Wendy Y. , Block Caroline , Schumer Susan , Bellon Jennifer R. , Valenza Carmine , Curigliano Giuseppe , Tolaney Sara M. , Lynce Filipa , Trapani Dario 
Published: December 2024

PURPOSE
Trimodal therapy (TMT) is the standard treatment for patients with nonmetastatic inflammatory breast cancer (IBC). TMT consists of neoadjuvant systemic therapy, modified radical mastectomy (MRM), and postmastectomy radiation therapy. Although broadly considered the best approach for IBC, in the United States, only a third of patients receive TMT. The rate is unknown in low- and middle-income countries (LMICs).

METHODS
A questionnaire in English and Spanish was constructed to assess the awareness, knowledge, and treatment patterns of IBC among providers in LMICs. It was emailed to the ONCOLLEGE global oncology collaborative group (a network of cancer care providers practicing in LMICs) and through other oncology network providers in LMICs, enhancing the sample size through a snowball sampling approach.

RESULTS
Between June and December of 2023, 145 participants completed the questionnaire, of whom 112 respondents were from 36 LMICs. All the providers reported that standard chemotherapy and MRM were available in their practice; 99.5% responded that radiation therapy was available. A total of 74.1% appropriately reported that IBC is a clinical diagnosis, although 51.8% stated that pathologic evidence of lymphatic emboli was required for IBC diagnosis. A third of the providers responded that >90% of their patients undergo all three parts of TMT.

CONCLUSION
Many patients with IBC in LMICs are not receiving TMT. Barriers to diagnosis and treatment were at least partially related to limited providers' comfort level and knowledge, suggesting that educational approaches can be impact-oriented interventions. On the basis of our findings, we created educational material, which will be translated into various languages and disseminated broadly to improve providers' awareness and knowledge of IBC.
Time Toxicity of Systemic Anticancer Therapy for Metastatic Lung Cancer in Routine Clinical Practice: A Nationwide Cohort Study
Authors: Ording Anne Gulbech , Skjøth Flemming , Poulsen Laurids Østergaard , Szejniuk Weronika Maria , Jakobsen Erik , Christensen Thomas Decker , Noble Simon , Overvad Thure Filskov 
Published: December 2024

PURPOSE
The concept of time toxicity of cancer treatment, defined as proportion of days from physical contact with the health care system, has been suggested as simple, patient-centered measure useful for shared decision making, particularly in incurable cancer. We investigated the extent of health care contacts in clinical practice in Danish patients with stage IV lung cancer starting first-line systemic anticancer therapies.

METHODS
This is a nationwide cohort study of newly diagnosed patients with stage IV lung cancer in Denmark who initiated treatment during 2019-2021 and followed for up to 1 year. The time toxicity after treatment initiation was calculated as the proportion and mean cumulative number of days with physical health care system contacts recorded in Danish registries. The remaining days without any physical contact were defined as home days. One-year cumulative mortality was also assessed.

RESULTS
We included 4,384 patients with stage IV lung cancer. One year survival was 45% after treatment initiation. Of days alive, the mean cumulative number of days with physical health care contacts was 56 days within 1 year. The corresponding number of home days was 198. Overall, 22% of days alive involved physical contact with the health care system, broadly similar for patients with non–small cell lung cancer (22%) and small cell lung cancer (24%). For specific regimens, the corresponding proportions were chemotherapy (24%), immunotherapy (21%), immunochemotherapy (21%), and targeted therapy (16%).

CONCLUSION
More than 1 in 5 days after initiation of systemic treatment for metastatic lung cancer was spent in physical contact with the health care system. This information may aid shared decision making by informing about expected burdens in relation to cancer therapy.
The absolute swampland
Authors: Eichhorn Astrid , Hebecker Arthur , Pawlowski Jan M. , Walcher Johannes 
Published: December 2024

Abstract
The “Swampland Program” aims to discriminate consistent-looking effective field theories that do not admit a UV completion in quantum gravity from those that do. While most often developed under the umbrella of string theory, several swampland criteria have been explored also in other contexts, especially asymptotically safe gravity. A comparison between different approaches can help to clarify the dependence of low-energy constraints on UV physics and thereby shed light on the universality of quantum gravity itself. In this perspective we summarise what is known about three important swampland conjectures in string theory and in asymptotic safety. We point out future lines of research that can help to understand to what extent swampland conjectures are absolute, i.e., hold in quantum gravity in general, or relative, i.e., belong only to a specific UV framework.
The psychological impact of birth trauma on fathers: a narrative review
Authors: Ellis Josh , Wier Jacqueline 
Published: December 2024

Background/Aims There is a paucity of evidence on how birth trauma can affect the mental health of fathers. This review aimed to determine the common psychological effects of witnessing traumatic events during birth for fathers. Methods A narrative literature review of primary research and literature reviews was conducted using the British Nursing Index, CINAHL, Maternity and Infant Care, PubMed and EBSCO. A total of 6 research articles were included. Results Data analysis generated three themes: toxic masculinity: the role of fathers in the birthing environment; unpreparedness: expectation vs reality; and relationships with partner and others. Conclusions Traumatic events during labour and birth can have a profound impact on both mother and father. Fathers may experience poor mental health in the perinatal period, which can impact their relationship with their partner and the baby. It was noted that some healthcare professionals were more supportive than others. Effective communication is essential to quality care provision, which should help to manage poor paternal mental health in the perinatal period. Implications for practice Services are needed to identify and address poor mental health in the perinatal period for both mothers and fathers. Antenatal education should include information about all potential outcomes during labour and birth. More healthcare professionals are needed with expertise in mental health, including the ability to assess and refer to specialist services where necessary.
Incorporating Volumetric Water Content (Capacitance) Sensors as an Automated Data Entry Solution for Irrigator Pro
Authors: Gallios Ioannis , Butts Christopher L. , Sorensen Ronald B. , Porter Wesley , Vellidis George 
Published: December 2024

HighlightsA new version of Irrigator Pro that pulls volumetric water content data from capacitance probe APIs was developed.The model was evaluated in replicated field trials for two years at two locations in Georgia, USA.The new version performs at least as well as the other versions of Irrigator Pro.The model was released and is publicly available on web and smartphone platforms. Abstract. Irrigator Pro (IP) is a public domain irrigation scheduling decision support tool (DST) developed by the United States Department of Agriculture’s National Peanut Research Laboratory (NPRL), which is widely used by peanut farmers and consultants in the southeastern U.S. The original version of the DST utilizes min/max soil temperature and precipitation to provide yes/no irrigation decisions for peanut. Recently, scientists at NPRL developed a sensor-based soil water balance model version of Irrigator Pro that automates the data collection process. This version allows either manual data entry or automated entry of soil matric potential data from sensors located at 0.1-, 0.2-, and 0.4-m depths. To make Irrigator Pro more accessible to growers and consultants, the work described here focused on incorporating volumetric water content (VWC) also sensed by capacitance probes as an automated data entry solution for Irrigator Pro. The deliverable of this project was to release a new version of Irrigator Pro that uses VWC data directly from capacitance probes. During the 2021 growing season, data were collected from two field sites in southwestern Georgia, USA, using replicated plot studies to develop the VWC version of Irrigator Pro. The VWC version was evaluated during the 2022 and 2023 growing seasons by comparing its performance to that of the other two versions of Irrigator Pro and to other advanced irrigation scheduling tools. The results indicated that the VWC version performed at least as well as the temperature and matric potential versions of Irrigator Pro in terms of irrigation water use and peanut yields. The VWC version of Irrigator Pro was then integrated into the Irrigator Pro platform and made available for public use. Ongoing evaluation of the model will continue in subsequent growing seasons with on-farm trials. Keywords: Decision support tools, Irrigation scheduling, Peanut irrigation, Precision agriculture, Smartphone application.
Sporotrichosis during pregnancy: A retrospective study of 58 cases in a reference center from 1998 to 2023
Authors: Freitas Dayvison Francis Saraiva , Cunha Rodrigo Pernas , de Oliveira Raquel de Vasconcellos Carvalhaes , de Macedo Priscila Marques , do Valle Antonio Carlos Francesconi , Rezende Ana Paula Marinho Barbosa , Eiras Rosangela Vieira , Curi André Luiz Land , Carvalho Erika Moreira , de Moraes Raissa Lima , Almeida-Paes Rodrigo , Zancopé-Oliveira Rosely Maria , Gutierrez–Galhardo Maria Clara 
Published: December 2024

Background
Pregnant women constitute a vulnerable population occasionally affected by zoonotic sporotrichosis. Treatment is challenging due to potentially teratogenic oral medications (itraconazole and saturated potassium iodide solution) or lack of clinical experience during pregnancy (terbinafine). Literature is scarce on sporotrichosis and pregnancy, mainly consisting of case reports.

Methodology/principal findings
This study consists of a cohort of 58 cases of pregnant women with sporotrichosis attended in a reference center in Rio de Janeiro from 1998 to 2023. The median age was 27 years old; the majority were black (64.4%); comorbidities prior to pregnancy were reported by 20.7% (including two people living with HIV/AIDS–PLHIV) and 6.8% developed conditions that are unique to pregnancy. In 75.9% of patients, they were pregnant when they acquired sporotrichosis, with a median gestational age of 17 weeks, and 24.1% became pregnant during treatment for sporotrichosis. The lymphocutaneous form occurred in 63.8% of patients, followed by the fixed form (19%), disseminated cutaneous form (12%) and extracutaneous/disseminated forms (5.2%). Thermotherapy was indicated for all (except 2) patients and cryosurgery was performed in 22 (37.9%). Amphotericin B was indicated for a patient with external ocular sporotrichosis and for the PLHIV with osteomyelitis in the right tibia. Cure occurred in 100% of those followed (n = 44) with the remainder lost to follow-up (n = 14)

Conclusions
Pregnant women with cutaneous sporotrichosis in this study recovered following physical therapies, suggesting these therapies may be effective. In cases of extracutaneous and disseminated forms, amphotericin B was indicated due to its safety profile in this population. Management of sporotrichosis during pregnancy requires a delicate assessment of the balance between maternal benefit and fetal risks.
A national cross-sectional survey of health literacy of caregivers attending Canadian pediatric emergency departments
Authors: Rajagopal Manasi , Ali Samina , Ma Keon , Yaskina Maryna , Morrison Andrea , Schreiner Kurt , Leung Julie , Scott Shannon , Beer Darcy , Clerc Paul , Crawford Tyrus , Gouin Serge , Poonai Naveen , Principi Tania , Stang Antonia , Weingarten Laura , Curran Janet ,   on behalf of the Pediatric Emergency Research Canada Family Needs Study Team
Published: December 2024

Background
Health literacy assessment is key to better meeting family needs and developing informed strategies to promote positive health outcomes for children. The objective of this study was to describe the health literacy of caregivers who use Canadian pediatric emergency departments and relate it to demographic and visit-specific variables.

Methods
This study utilized a descriptive, cross-sectional survey design with medical record review. A bilingual survey was electronically administered to caregivers presenting to 10/15 Canadian pediatric emergency departments. Health literacy was assessed using the Newest Vital Sign tool.

Results
1957 caregivers completed the Newest Vital Sign assessment. Caregivers’ mean age was 37.8 ± 7.7 years, 74.3% (1449/1950) were mothers and 51.9% (993/1912) had a university/professional degree. 12.0% (235/1957) had a high likelihood of limited health literacy, 16.5% (323/1957) had possible limited health literacy and 71.5% (1399/1957) demonstrated adequate health literacy. Adequate health literacy scores were associated with having a university/professional degree [aOR 1.47 (95% CI 1.11–1.94)] and having a household annual income of over $25,000 [aOR 4.10 (2.66–6.31)]; they were inversely associated with having a total of 4 or more children [aOR 0.61 (0.40–0.91)] and having a main language at home other than English or French [aOR 0.32 (0.23–0.43)].

Interpretation
With over 1/4 caregivers facing health literacy challenges, health care providers in emergency departments must be cognizant of their communication and education approach when caring for families and providing at-home care guidance. Clinicians should consider applying health literacy principles to all family encounters to help address healthcare disparities.
Who Makes the Franchise? Essays on Fandom and Wilderness Texts in Popular Media, Rhonda Knight and Donald Quist (eds) (2022)
Authors: Alberto Maria K. 
Published: December 2024

Review of: Who Makes the Franchise? Essays on Fandom and Wilderness Texts in Popular Media, Rhonda Knight and Donald Quist (eds) (2022)
Jefferson, NC: McFarland & Company, Inc., 264 pp.,
ISBN 978-1-47668-415-4, p/bk, $65.00
Trends in Cardiovascular Disease–Related Mortality in Texas
Authors: Usman Muhammad Shariq , Jamil Adeena , Chunawala Zainali , Alam Mahboob , Nambi Vijay , Abushamat Layla A. , Misra Arunima , Virani Salim S. , Ballantyne Christie M. , Taffet George E. , Nasir Khurram , Goel Sachin , Al-Kindi Sadeer , Butler Javed , Minhas Abdul Mannan Khan 
Published: December 2024

Abstract

Background:
Cardiovascular disease (CVD) is associated with high mortality in the United States, but the burden of CVD mortality is unevenly distributed between demographic and geographic subgroups, with poor characterization of state-specific trends. In this study, the disparities in CVD-related mortality trends in Texas and the United States from 1999 to 2019 were assessed.

Methods:
Trends in CVD-related mortality were evaluated through analysis of the Multiple Causes of Death Files from the National Center for Health Statistics. Crude and age-adjusted mortality rates (AAMRs) per 100,000 population with associated annual percentage changes were determined. Joinpoint regression was used to assess trends in the CVD-related mortality rates.

Results:
Between 1999 and 2019, 29,455,193 CVD-related deaths were reported in the United States, of which 1,937,166 occurred in Texas. After an initial decline in the overall AAMR in Texas (annual percentage change, −2.5 [95% CI, −2.8 to −2.1]), a steady level was maintained from 2009 to 2019 (annual percentage change, 0.2 [95% CI, −0.5 to 0.2]). In the United States, after initial decline, AAMR plateaued from 2011 to 2019. Overall, CVD-related AAMR was slightly higher in Texas than in the overall United States (AAMR, 674.1 [95% CI, 673.2-675.1] vs 654 [95% CI, 653.8-654.3]). Men, non-Hispanic Black people, and people 85 years of age and older had the highest AAMRs in Texas and nationwide. Nonmetropolitan areas, both nationally and in Texas, consistently had higher mortality rates. The AAMRs also varied significantly by county within Texas.

Conclusion:
Despite an initial period of decline, CVD-related mortality rates have plateaued in Texas and the United States. Higher AAMRs were observed in Texas than in the overall United States. Prevalent disparities also exist based on demographic and geographic subgroups.
Experimental investigation on low-velocity-impact and post-impact-tension behaviors of GFRP T-joints after hydrothermal aging
Authors: You Peiyu , Liu Cuilong , Yao Xiaobang , Xu Kaixin , Li Mingjie , Wu Ye , Luo Jixiang 
Published: December 2024

Abstract
As an integrated structural unit, composite T-joints are used to transfer the load between two vertical planes, such as the wing box of an aircraft. The article aims to investigate the failure mechanism of the glass fiber-reinforced polymer (GFRP) composite T-joints subjected to low-velocity impact on the weak deltoid and post-impact tension after hydrothermal aging. First, the improved vacuum-assisted resin infusion suitable for the fabrication of GFRP T-joints is employed. Second, the hydrothermal aging is conducted at 25°C and 65°C with the same relative humidity of 85% for 1–6 weeks. Finally, the impact resistance and tensile strength are analyzed based on response history and damage morphology. The results show the significant degradation of impact strength and stiffness of GFRP T-joints after hydrothermal aging and with the increase in aging time and temperature. In the failure mode of post-impact tension, the interlaminar cracks in the deltoid propagate in the horizontal and vertical directions, and there is a large gap in horizontal crack length between aged and non-aged T-joints.
Gender Differences in Autism Spectrum Disorder: A Systematic Review of Diagnosis, Intervention, and Outcomes
Authors: Mao Haoran , Cheng Lulu , Zhang Yu , Zhang Fang 
Published: December 2024

Abstract
Autism Spectrum Disorder (ASD) presents distinct diagnostic and treatment challenges, particularly in understanding gender differences in symptom presentation and intervention effectiveness. The male-to-female ASD diagnosis ratio, often cited as 4:1, is increasingly questioned due to the subtler symptom presentation in females, contributing to significant underdiagnosis. This systematic review followed PRISMA guidelines to analyze data from 47 studies, examining gender differences in ASD diagnosis, symptom expression, and intervention effectiveness. Females with ASD more frequently exhibit internalizing symptoms like anxiety, social withdrawal, and emotional regulation difficulties, in contrast to the externalized behaviors typical of males. Analysis of over 1,000 individuals reveals that 75 % of males exhibit hallmark traits like repetitive behaviors and speech delays, compared to only 40 % of females. Conversely, over 60 % of females demonstrate social camouflaging behaviors, masking their symptoms and complicating their diagnosis. Additionally, this research investigates gender differences in response to intervention, finding that while 70 % of males benefit from traditional interventions like Applied Behavior Analysis (ABA) and Cognitive Behavioral Therapy (CBT), only 45 % of females show comparable progress. Females with ASD benefit more from therapies that focus on emotional regulation, social communication, and adaptive behaviors, underscoring the need for gender-sensitive approaches. Based on these findings, the study advocates for the development of diagnostic tools that account for gender-specific ASD traits, urging healthcare professionals to be more vigilant in identifying subtler ASD symptoms in females. Furthermore, intervention programs should be restructured to integrate social and emotional components that address the unique profiles of females with ASD. Families and caregivers must also be educated to recognize these gender-based differences, enabling earlier identification and more personalized care. Addressing these diagnostic and intervention disparities will significantly improve long-term outcomes for females with ASD.
Placental growth factor as a predictive marker of preeclampsia in twin pregnancy
Authors: Qi Guijie , Yao Ling , Liu Zhiming , Guo Wanru , Liu Heng , Zhang Jinghua , He Yulian , Jiang Tiancong 
Published: December 2024

Abstract

Objectives
Placental growth factor (PlGF) has been reported as a good biomaker for the prediction of preeclampsia occurring in the short term in singleton pregnancies, in women presenting with clinical suspicion of preeclampsia. This study aims to evaluate the predictive value of the PlGF in twin pregnancies.

Methods
Twin pregnancies with clinically suspected preeclampsia (24 weeks 0 days–36 weeks 6 days of gestation) were enrolled in this study. The threshold of PlGF for predicting preeclampsia was determined on the basis of a receiver-operating characteristic curve to predict preeclampsia and the short-term occurrence of preeclampsia.

Results
Within 1 week, 2 weeks, and 4 weeks of testing respectively, a cutoff value of 215 pg/mL for PlGF to predict preeclamsia in twin pregnancies suspected to have preeclampsia has a specificity of 100 %[51.7 %, 100 %], 100 %[62.9 %, 100 %], 93.8 %[667.6 %, 99.7 %], and a negative predictive value of 100 %[94.8 %, 100 %], 100 %[95.0 %, 100 %], and 98.9 %[93.0 %, 99.9 %].

Conclusions
A cutoff value of 215 pg/mL for PlGF is a useful tool to exclude the development of preeclampsia within 4 weeks of measurement.
Degrees of (L, M)-fuzzy bornologies
Authors: Çetkin Vildan 
Published: December 2024

Abstract
This article is devoted to present the degree to which a mapping defined from

L

X

{L}^{X}

to

M
,

M,

which is an

(

L
,
M

)

\left(L,M)

-fuzzy bornology in the sense of Liang et al. In this respect, the degree to which

L

L

-subset is bounded according to the given bornological structure is described. In addition, the notions of boundedness degree and the boundedness preserving degree of a mapping defined between bornological spaces are introduced. The characterizations of the provided notions are studied.
Ethical Implications of German-Hebrew Homophony: Analyzing Dan Pagis’ “Sealed Railcar” Cycle
Authors: Kühne Jan 
Published: December 2024

Abstract
This paper explores the complex interplay of German and Hebrew in the context of Israeli literature, focusing on Dan Pagis’ “Sealed Railcar” cycle of poems (1970). It delves into the historical background of how German became a repressed language in Israel, and the impact of the Shoah on this linguistic repression. The study introduces the concept of interlingual homophonic hermeneutics as a methodological approach to uncovering hidden German subtexts within Hebrew texts. Specifically, it analyzes the iconic poem “Written with Pencil in a Sealed Railcar” to reveal a German-Hebrew homophonic subtext and the profound ethical questions it raises.
Ethical-Religious Seduction: Laplanche and Kierkegaard on the Priority of the Other
Authors: Kline Peter 
Published: December 2024

Abstract
This essay offers a psychoanalytic perspective on ethics utilizing Jean Laplanche and Søren Kierkegaard. It proposes a homology between Kierkegaard’s ”God” and Laplanche’s “primal adult” as well as between Kierkegaard’s account of the indirection of love and the role of the analyst in the transference relationship. Both Kierkegaard and Laplanche center scenes of second-person relation in which a seductive asymmetry calls forth a rigorous ethics of unknowing.