bluuebunny/crossref_metadata_2025_split huggingface dataset:
Karakteristik Bangunan Rumah Tinggal Di Pesisir Kabupaten Majene Terhadap Gempa
Authors: Yusman Yusman 
Published: September 2021

Pertemuan lempeng Indo-Australia, Lempeng Eurasia, dan Lempeng Pasifik membuat kondisi geologis Indonesia menjadi tidak stabil sehingga rawan terjadi gempa. Kabupaten Majene termasuk wilayah rawan gempa sehingga dianjurkan bangunan yang tahan gempa. Tujuan dari penelitian ini adalah untuk mengetahui dan mengklasifikasikan jumlah rumah yang terdampak gempa serta penyebab tingginya tingkat kerusakan. Metode yang digunakan adalah metode survei dan wawancara. Proses survei dilakukan dengan mengamati rumah warga dan mengklasifikasikan tingkat kerusakan berdasarkan petunjuk teknis yang dikeluarkan oleh Tim Balai Litbang Bahan & Struktur Bangunan Kementerisan PUPR tahun 2019 . Dari hasil survei diperoleh rumah rusak berat berjumlah 1.713, rusak sedang berjumlah 1.060 dan rusak ringan berjumlah 1.107. Dari hasil survei dan wawancara dipeoleh bahwa kondisi struktur bangunan rumah pada umumnya tidak sesuai dengan panduan pembangunan perumahan dan pemukiman oleh Tim Balai Litbang Bahan & Struktur Bangunan Kementerisan PUPR. 2016 yaitu tidak memiliki sloof, ring balok atau kolom sehingga mengakibatkan presentasi kerusakan rumah lebih tinggi.
DCF (Dieng Culture Festival), Wujud Harmonisasi Antara Kearifan Lokal, Agama dan Sosial Ekonomi di Masyarakat Dataran Tinggi Dieng
Authors: Suprobowati Gayatri Dyah 
Published: September 2021

<p>Tujuan penelitian ini, untuk mengetahui peran nilai-nilai kearifan lokal yang ada dalam <em>Dieng Cultural Festival</em> (DCF) sebagai wujud harmonisasi antara nilai-nilai kearifan lokal, agama dan sosial ekonomi di Masyarakat Dataran Tinggi Dieng. Formulasi peran tersebut dikembangkan berdasar temuan hasil studi lapangan yang di analisis secara secara komprehensif dengan mengharmonisasi hukum tidak tertulis (adat) dan ajaran agama dan masyarakat dataran tinggi dieng juga hukum tertulis ( hukum positif). Masyarakat dataran tinggi Dieng merupakan bagian dari Suku Jawa. Namun karena kebudayaan Jawa yang masih mendarah daging, masyarakat dataran tinggi Dieng termasuk pemeluk agama Islam yang sinktretisme. Misalnya masih adanya ritual adat Jawa yang berbau animisme dan dinamisme. Fenomena yang terjadi pada masyarakat dataran tinggi Dieng adalah adanya anak berambut gimbal. Ada berbagai kelompok dan agama di Dieng. Hasil dari saling pengertian dan menghormati sesama adalah toleransi beragama terus terjaga di daerah tersebut sebagai bentuk pencegahan terjadinya konflik sosial. Penelitian ini merupakan penelitian sosiolegal dengan metode empiris dengan menggali sumber data primer dari masyarakat Dieng. Data sekunder berupa bahan hukum primer, sekunder dan tersier. Instrumen pengumpul data<strong> </strong>menggunakan wawancara, <em>Focus</em> <em>Group</em> <em>Discussion</em> (FGD) dan studi kepustakaan hukum adat untuk pencegahan konflik. Analisis data model kualitatif dengan interpretasi berdasar teori <em>(theoritical interpretation) </em>dan ditarik generalisasi sebagai rumusan yang bersifat ideal <em>(ius constitutum). </em>Rencana penelitian yang akan dilakukan untuk memformulasikan peran nilai-nilai kearifan lokal dalam DCF, dengan tahapan (1) Mendeskripsikan nilai-nilai yang dijadikan sumber kearifan lokal yang terdapat dalam DCF di dalam Masyarakat Dataran Tinggi Dieng; (2) Menganalisis apakah nilai-nilai kearifan lokal dalam DCF dapat berperan sebagai sarana untuk memperkuat harmonisasi kaitannya dengan agama dan sosial ekonomi di Masyarakat Dataran Tinggi Dieng dalam perspektif UU No. 7 Tahun 2012 tentang Penanganan Konflik Sosial. Luaran penelitian berupa Publikasi Jurnal nasional terakreditasi yakni Jurnal .....(Humas FH UNS) dengan judul Pemberdayaan Kearifan Lokal , agama dan sosial ekonomi Sebagai Upaya Memperkuat Harmonisasi sosial Di Masyarakat Dataran Tinggi Dieng Dalam Perspektif Sosiologi Hukum.</p><p><em>Keyword : </em><em>Dieng Cultur Festival (</em>DCF<em>, )</em><em>harmonisasi soasial</em><em>, kearifan lokal, masyarakat Dieng, UU No.17 Tahun 2012 </em></p>
Clinical verification of body mass index and tumor immune response in patients with breast cancer receiving preoperative chemotherapy
Authors: Takada Koji , Kashiwagi Shinichiro , Asano Yuka , Goto Wataru , Ishihara Sae , Morisaki Tamami , Shibutani Masatsune , Tanaka Hiroaki , Hirakawa Kosei , Ohira Masaichi 
Published: August 2021

Abstract
Purpose

The body mass index (BMI) is commonly used as a simple indicator of obesity; patients with early-stage breast cancer who are obese (OB) per BMI measurements have been shown to have high postoperative recurrence and low survival rates. On the other hand, it has been shown that lymphocytes present in the vicinity of malignant growths that are involved in the tumors’ immune responses influence the efficacy chemotherapy. Therefore, we hypothesized that OB patients with breast cancer have a lower density of tumor-infiltrating lymphocytes (TILs), which may influence the therapeutic effect of preoperative chemotherapy (POC). In this study, we measured pretreatment BMI and TILs in patients with breast cancer who underwent POC, examined the correlations between these two factors, and retrospectively analyzed their therapeutic outcomes and prognoses.
Methods

The participants in this study were 421 patients with breast cancer who underwent surgical treatment after POC between February 2007 and January 2019. The patient’s height and weight were measured before POC to calculate the BMI (weight [kg] divided by the square of the height [m2]). According to the World Health Organization categorization, patients who weighed under 18.5 kg/m2 were classified as underweight (UW), those ≥ 18.5 kg/m2 and > 25 kg/m2 were considered normal weight (NW), those ≥ 25 kg/m2 and < 30 kg/m2 were overweight (OW), and those ≥ 30 kg/m2 were OB. The TILs were those lymphocytes that infiltrated the tumor stroma according to the definition of the International TILs Working Group 2014.
Results

The median BMI was 21.9 kg/m2 (range, 14.3–38.5 kg/m2); most patients (244; 64.5%) were NW. Among all 378 patients with breast cancer, the TIL density was significantly lower in OB than in NW and OW patients (vs. NW: p = 0.001; vs. OW: p = 0.003). Furthermore, when examining patients with each breast cancer type individually, the OS of those with TNBC who had low BMIs was significantly poorer than that of their high-BMI counterparts (log rank p = 0.031).
Conclusions

Our data did not support the hypothesis that obesity affects the tumor immune microenvironment; however, we showed that being UW does affect the tumor immune microenvironment.
Effects and Long-Term Outcomes of Partial Anterior Myometrial Resection and Reconstruction Under Tourniquet and/or Prophylactic Abdominal Aorta Balloon Occlusion in Patients with Placenta Percreta: A Retrospective Cohort Study
Authors: Zhao Huidan , Zhao Xianlan , Chen Chen , Tao Ya , Guo Rui Xia 
Published: August 2021

Abstract
Purpose: Placenta percreta is the most serious subtype of placenta accreta spectrum (PAS) disorders. In this study, we propose a new procedure for controlling intraoperative bleeding. We aimed at evaluating the effect and long-term outcomes of Partial Anterior Myometrial Resection and Reconstruction under tourniquet and/or prophylactic abdominal aorta balloon occlusion in patients with placenta percreta.Methods: This was a retrospective study involving pregnant patients with clinically confirmed placenta percreta who delivered by cesarean section between January 1st, 2018 and June 30th, 2020. A total of 334 pregnant women were recruited in this study. The 142 women that were subjected to this new method were regarded as the observation group while 194 pregnant women that were treated with other sutures were regarded as the control group. Demographic characteristics, placental accreta score, estimated blood loss (EBL), operative time, blood transfusion rate and volume, neonatal weight, post-operative hospital stays and costs were evaluated. Short-term complications, including fever, hematoma, thrombus, bladder rupture and ICU transfer rate, as well as long-term outcomes including breast feeding, menstruation, intrauterine adhesion, and chronic abdominal pain among others were followed up in the outpatient clinic and by phone calls.Results: For all cases, EBL in the observation and control groups were 1200 (687~1812) ml and 1300 (800~2500) ml; operative time were 99.5 (84.0~120.0) min and 109.0 (83.8~143.0) min; while lengths of postoperative hospital stays were 4 (4~7) and 5 (4~7.5) days, respectively. The observation group exhibited significantly better outcomes than the control group. There were no significant differences in placental percreta scores, costs, blood transfusion volume, neonatal weight, fever, hematoma, thrombus, bladder rupture and ICU transfer rates between the two groups. All patients, except one in control group, had preserved uterus. There were no statistically significant differences in short-term and long-term complications between the two groups.Conclusions: When combined with prophylactic abdominal aorta balloon occlusion and/or tourniquet, Partial Anterior Myometrial Resection and Reconstruction is highly effective in reducing intraoperative blood loss and hysterectomy in placental percreta. However, we should pay attention to short-term and long-term complications, especially to the complications associated with aorta balloon occlusion.
Sensei: How Many Samples to Tell Evolution in Single-Cell Studies?
Authors: Liang Shaoheng , Willis Jason , Dou Jinzhuang , Mohanty Vakul , Huang Yuefan , Vilar Eduardo , Chen Ken 
Published: September 2021

Abstract
Cellular heterogeneity underlies cancer evolution and metastasis. Advances in single-cell technologies such as single-cell RNA sequencing and mass cytometry have enabled interrogation of cell type-specific expression profiles and abundance across heterogeneous cancer samples obtained from clinical trials and preclinical studies. However, challenges remain in determining sample sizes needed for ascertaining changes in cell type abundances in a controlled study. To address this statistical challenge, we have developed a new approach, named Sensei, to determine the number of samples and the number of cells that are required to ascertain such changes between two groups of samples in single-cell studies. Sensei expands the t-test and models the cell abundances using a beta-binomial distribution. We evaluate the mathematical accuracy of Sensei and provide practical guidelines on over 20 cell types in over 30 cancer types based on knowledge acquired from the cancer cell atlas (TCGA) and prior single-cell studies. We provide a web application to enable user-friendly study design via https://kchen-lab.github.io/sensei/table_beta.html.
Typhoid Fever Complicated with Bowel Perforation in an HIV Patient
Authors: Karunathilake Parackrama , Jayalath Thilak , Abeygunawardena Shamali , Ralapanawa Udaya 
Published: September 2021

Abstract
Background
Patients with HIV infection often develop multiple complications and comorbidities, including malignancies and opportunistic infections. The association of HIV infection with typhoid fever remains unclear, though there is a clear risk of typhoid in HIV infected persons. Therefore, the diagnosis of typhoid should be considered in HIV infected individuals, mainly when they present with severe ulcerative diarrhoea.
Case Presentation
A 38-year-old gentleman presented with fever with significant weight loss and anorexia for eight months. He had worked abroad in a middle east country and had recently returned to Sri Lanka. On examination, he was thinly built with a BMI of 18 kg/m2. The initial full blood count revealed lymphopenia, anaemia and thrombocytopenia. He also had mild hyponatremia. His HIV Ag/Ab combo assay became positive, and he was found to have a low CD4 count. While on antiretroviral therapy, he developed nausea, vomiting and diarrhoea while continuing the preexisting fever followed by severe dyspnoea and epigastric pain and tenderness associated with tachypnoea, tachycardia and hypotension. The urgent chest X-ray revealed gas under the diaphragm. An urgent exploratory laparotomy was done, and he was found to have distal ileal perforation with a typhoid ulcer which was histologically confirmed later. During the postoperative period, the patient developed severe pneumonia, scummed despite all the resuscitation care given.
Conclusion
Fever in HIV patients could be due to HIV itself, opportunistic infections or malignancies. The diagnosis of typhoid should be considered in HIV infected individuals, mainly when they present with severe ulcerative diarrhoea, constipation or bowel perforation. Salmonella typhi infection in HIV/AIDS patients may cause life-threatening complications, where the case fatality rate of typhoid significantly increase when present concurrently with HIV, and the mortality further increases with delayed diagnosis.
Pollution Evaluation And Health Risk Assessment of Heavy Metals In The Surface Water of A Remote Island Nijhum Dweep, Northern Bay of Bengal
Authors: Rima Sabrina Akhter , Rahman Mahfuzur , Saha Subrota Kumar , Saima Jerin , Hossain Mohammad Sabbir , Tanni Tamisra Nath , Bakar Muhammad Abu , Siddique Mohammad Abdul Momin 
Published: September 2021

Abstract
The current study aimed to evaluate the distribution and status of heavy metal contamination of surface water in the Nijhum Dweep, northern Bay of Bengal. Ten surface water samples were collected to determine the heavy metals and the associated human health risk. The mean concentrations of the selected heavy metals were ranked in descending order of Fe (3.412 mg/L) > Mn (0.3911 mg/L) > Pb (0.3 mg/L) > Co (0.2918 mg/L) > Zn (0.230 mg/L) > Ni (0.1943 mg/L) > Cu (0.167 mg/L) > Cd (0.11 mg/L) > Cr (0.077 mg/L). All the metals except Cd, Pb, and Ni were found uncontaminated, and these three metals influenced the values of heavy metal pollution indices. Heavy metal evaluation index (HEI), heavy metal pollution index (HPI), and Nemerow pollution index (NI) revealed that the surface water of the study area is low to moderately contaminated by these selected heavy metals. Hazard quotient (HQ) and hazard index (HI) for adults and children showed no non-carcinogenic risk of heavy metals from dermal exposure pathways except station number 4 at the south of the Nijhum Dweep due to high Mn concentration. No possible carcinogenic risk was found from the analyzed metals. Several local sources of heavy metals were found during the field investigation, such as domestic effluents, small-scale metallurgical activities, oil spills from ships, and fishing trawlers. Again, industrial effluents and agrochemicals from upstream regions also contribute to heavy metal pollutions in downstream coastal regions of Bangladesh. Even though the surface water pollution level is low in the study area, the authority should take proper management and monitoring strategy for sustainability.
Decreased B Lymphocytes Subpopulations Are Associated With Higher Atherosclerotic Risk in Elderly Patients With Moderate-to-severe Chronic Kidney Diseases
Authors: Lin Jieshan , Tang Bin , Feng Zhanwu , Hao Wenke , Hu Wenxue 
Published: September 2021

Abstract
Aim: Cardiovascular diseases (CVD) are the leading cause of death in patients with chronic kidney disease (CKD), and the risk of CVD increases with reductions in renal function. This study aims to investigate the potential roles of B lymphocyte populations in subclinical atherosclerosis (measured by intima-media thickness, IMT) and prognosis in elderly patients with moderate-to-severe CKD.Methods: In this study, a total of 219 patients (143 moderate-to-severe CKD patients with stage 3-4 and 76 non-CKD controls) were recruited. B cell subsets: B1 cells (CD19+CD5+) and B2 cells (CD19+CD5–) were analyzed by flow cytometry. Intima-media thickness (IMT) was measured by ultrasound. Correlations between the B cell subsets with IMT and clinical outcomes were analyzed.Results: CKD patients showed increased IMT (P=0.006). The level of B, B1 and B2 cells were decreased in CKD patients. Correlation analysis showed that IMT was positively correlated with systolic blood pressure, protein/creatinine ratio and diabetes (P<0.05), and were negatively correlated with B, B1 and B2 lymphocytes (P<0.05). IMT was increased in lower level of B (≤ 0.06 × 109 /L) and B2 cells (≤ 0.05 × 109 /L) (P<0.05). Kaplan-Meier analysis showed that patients with lower level of B, B1 and B2 cells exhibited worse survival (P<0.05).Conclusions: Our results showed that decreased B1 and B2 lymphocytes were correlated with atherosclerosis and worse survival, which indicates that B lymphocytes might involve in atherosclerosis and associated the prognosis of elderly patients with moderate-to-severe CKD.
Finnish Late Adolescents' Physical Activity During COVID-19 Spring 2020 Lockdown
Authors: Ng Kwok , Koski Pasi , Lyyra Nelli , Palomaki Sanna , Mononen Kaisu , Blomqvist Minna , Vasankari Tommi , Kokko Sami 
Published: September 2021

Abstract
BackgroundPhysical activity (PA) is recognised as one of the leading and effective strategies to prevent non-communicable diseases that boosts the immune system to fight against diseases. Closures of schools, sport clubs and facilities because of COVID-19 reduced the opportunities to participate in PA. We aimed to examine physical activity levels of late adolescents, the contexts to be physical active and its changes during the spring 2020 lockdown. MethodsA nationally represented sample of late adolescents in general upper secondary school (n=2408, females = 64%, mean age = 17.2y, SD=0.63) completed online surveys on PA between March and May 2020. Multinominal logistic regression analyses were performed to identify correlates with PA, and decision tree analyses to ascertain the perceived changes on PA during lockdown based on sport club aspirations and levels of PA. ResultsAmong the late adolescents, the distribution of PA frequency was 23% (0-2days/week), 35% (3-4days/week), 30% (5-6 days/week) and 12% (7 days/week), and differences between males and females were not statistically significant. Participation in PA both indoor and outdoor were 50 times more likely to report daily PA (OR=54.28, CI=15.16-194.37). A quarter of late adolescents not part of a sports club yet their PA levels increased. Although sports club members generally perceived they did less PA during lockdown, over a third of sport club members with competitive aspirations reported daily PA. ConclusionsOverall, late adolescents reported their PA levels decreased during lockdown. Findings from this study continue to demonstrate factors associated with PA in the context of the COVID-19 lockdown.
Naturally occurring nanoparticles in two biological wastewater treatment plants in Southern California
Authors: Smeraldi Josh , Tseng Linda Y , Dutta Ishir , Ganesh Rajagopalan , Rosso Diego 
Published: September 2021

Abstract
Naturally occurring nanoparticles (NONPs) in wastewater are generally considered colloids, but their production and size distribution are not well understood. NONPs are more abundant than engineered nanoparticles (ENPs) in wastewater, where they may cause membrane fouling, harbour pathogens, and transport contaminants to the environment. In this study we aimed to understand the seasonal behaviour as well as the quantity and size of suspended particles (both unfiltered and filtered through a 450 nm filter) along two water resource recovery facilities (WRRFs, formerly wastewater treatment plants) located in Southern California. We also investigated the factors that correlate with their occurrence. We found that both of the biological secondary treatments investigated, conventional activated sludge process (ASP) and trickling filter (TF), were more efficient in removing suspended particles larger than 450 nm than they were smaller ones. The results show that current treatment processes are not designed to remove nano-sized particles efficiently. Additionally, there was a significant and direct correlation between influent dissolved chemical oxygen demand (COD) and the abundance of suspended particles both larger and smaller than 450 nm, suggesting that the suspended particles increased with dissolved COD in the WRRFs and thus were biogenically generated during the wastewater treatment.
Formation of High-Quality Solutions In The Construction of Aeromonitoring Data Banks
Authors: Nekrasov Hlib , Vostrikov Alexander , Prokofeva Ekaterina , Adero Nashon 
Published: August 2021

Abstract
Background: This article discusses the approach to the implementation of the project for the extraction and the methodology of preliminary processing of the obtained data with the aim of centralized accumulation for collective multipurpose use of the databank on the example of carbon dioxide emissions into the atmosphere by air transport for a given territory. It should be noted that on the basis of morphological analysis, processing, as well as the classification of spatial objects of the geodatabase and additional information, it is subsequently possible to organize, for example, a system of geoecological monitoring.Methods: At the fundamental level, the research used integration and process-based approaches, the method of extrapolation, expert methods of evaluation, random selection and analytical comparisons, a set of methods of spatial analysis based on various instruments and sources. In this study are used of open standards OGC, web, GIS technologies and the Internet for the formation, processing and storage of spatial data, their unambiguous geolocation, the implementation of territorial selections and visualization of results.Results: The set of data, which was organized according to the proposed and defined rules, made it possible to assess the structural processing of geospatial data, and to prepare a visual representation of the impact of aviation on the environmental situation over the designated geographic area.Conclusions: The transport industry was chosen as the object of research, but this solution can also be successfully applied to other logistics and industrial areas. During the implementation of the project, the analysis of the subject area was carried out, the architecture of the future prototype of the databank was designed, the accumulated data from the sources was structured, and a database was selected for storing them, taking into account the provision of high availability and ensuring stable operation under high loads. For the convenience of displaying data, an interactive visualization tool with a convenient and friendly user interface has been developed.