bluuebunny/crossref_metadata_2025_split huggingface dataset:
Self Potential Development Through Computer Mediated Communication on Instagram Application
Authors: Purwaningtyas Grace Setyo , Pawito Pawito , Nurhaeni Ismi Dwi Astuti 
Published: October 2021

Communication technology and the internet have developed quite rapidly from time to time. The development of communication technology and the internet has changed the way human’s communication. Human interaction is no longer limited to face-to-face meetings, but has now shifted to interaction or communication using computer and internet media which are not limited to space and time. This mediated communication is known as Computer Mediated Communication (CMC). Communication through the CMC was developed by various application providers to facilitate internet users in communicating, one of which is through the Instagram application. Text, images and videos are included in the type of computer mediated communication (CMC) interaction. The CMC interaction is used by internet users from various circles, including millennial mothers. This research was conducted to find out how the role of CMC in developing self-potential among millennial mothers. This research is a qualitative research using semi-structured interviews as a data collection method. The findings in this study indicate that informants are selective in presenting themselves through the selection of images, videos and descriptions before uploading on the Instagram page so that they are able to display their potential.
Developmental Stages of Irfani Poetry
Authors: Imomnazarov Muhammadjon , Jumaeva Kamola 
Published: October 2021

This article discusses the stages of development of irfani poetry in Persian classical literature of the XII-XV centuries. It describes the relationship between the two aspects of the problem, the first aspect of the concepts of tasavvuf and irfan, and the second aspect of what is meant by tasavvufi literature or irfani literature. In illuminating the stages of development of irfani poetry, we have divided this 8-century process of creative development into three major stages, taking into account the fact that the literature of the Muslim region has undergone a great development in terms of perception and creative reflection of the world during the VIII-XV centuries. In this article, the reason why irfani poetry is divided into three major stages and the factors that motivate it have been proved by providing evidence.
Recurrent Retinal Detachment After Pars Plana Vitrectomy For Rhegmatogenous Retinal Detachment
Authors: Fu Yan , Xie Tian-hao , Gu Zhao-Hui , Yang Na , Geng Ren-Fei , Zhang Yue-ling 
Published: October 2021

Abstract
Background

The recurrence of retinal detachment (RD) following rhegmatogenous retinal detachment (RRD) is a relatively common complication that threatens vision and requires further surgery. The purpose of this study was to investigate the risk factors and visual outcomes of recurrent RD following pars plana vitrectomy (PPV) for primary RRD.
Methods

This was a retrospective follow-up of 343 eyes that underwent initial PPV surgery for primary RRD. Patients were divided into a recurrence group and a reattachment group. The main outcome measures included causative factors, visual outcomes related to the recurrence of RD, and the perioperative factors most affecting the recurrence of RD.
Results

After retinal reattachment, we observed RD recurrence after PPV for primary RRD in 42 out of 343 eyes (12.2%) during the follow-up period. Most causes of recurrence (69%) occurred within 6 months of surgery. Univariate analysis showed that the presence of proliferative vitreoretinopathy (PVR) ≥ Grade C was significantly associated with recurrent RD (P = 0.003). Logistic regression analysis further showed that a PVR ≥ Grade C (odds ratio [OR]: 9.421; 95% confidence interval [CI]: 2.432 - 56.39; P = 0.020) was a significant predictor for the development of recurrent RD. Compared with the reattachment group, the recurrence group exhibited a significant decline in best-corrected visual acuity (BCVA) at the last follow-up visit (P = 0.000). Eyes with PVR prior to primary surgery, or at the diagnosis of re-detachment, showed a worse final BCVA.
Conclusions

Our analysis shows that the predominant risk factor for the recurrence of RD is a PVR ≥ Grade C. PVR prior to primary surgery, or at the diagnosis of re-detachment, was also shown to limit the recovery of final visual acuity.
Spatiotemporal Correlations Between Water Quality And Microbial Community of Typical Inflow River Into Taihu Lake, China
Authors: Zhang Yajie , Zhang Ye , Wei Lecheng , Li Mengyan , Zhu Weitang , Zhu Liang 
Published: October 2021

Abstract
Changxing River, which is a typical inflow river into the Taihu Lake and occurs severe algae invasion, is selected to study the effect of different pollution sources on the water quality and ecological system. Four types of pollution sources, including the estuary of Taihu Lake, discharge outlets of urban wastewater treatment plants, storm water outlets, and non-point source agricultural drainage areas are chosen, and next-generation sequencing and multi-variate statistical analyses are used to characterize the microbial communities and reveal their relationship with water physicochemical properties. Results showed that ammonia nitrogen (NH4+-N), total nitrogen (TN), and total phosphorus (TP) are the main pollutant in Changxing River, especially at storm water outlets. At the same time, the diversity of microbial communities was the highest in the summer, and dominant phyla included Proteobacteria (40.9%), Bacteroidetes (21.0%) and Euryarchaeota (6.1%) under the condition of algal bloom. Water temperature (T), air pressure (P), concentrations of TP and CODMn were the important variables for the succession of microbial community. From the perspective of different pollution types, relative abundances of Microcystis and Nostocaceae at the estuary of Taihu Lake were correlated positively with dissolved oxygen (DO) and pH, and Pseudomonas and Arcobacter were correlated positively with concentrations of TN and nitrate nitrogen (NO3--N) at storm water outlets. The results provide a reference for the impact of pollution types on river microbial ecosystem under complex hydrological condition and a guidance for the selection of restoration techniques for polluted rivers entering an important lake.
Characteristics of Recurrent Cases after Conservative Therapy in Adolescent Lumbar Spondylolysis
Authors: Tatsumura Masaki , Gamada Hisanori , Okuwaki Shun , Eto Fumihiko , Nagashima Katsuya , Mammoto Takeo , Hirano Atsushi , Funayama Toru , Yamazaki Masashi 
Published: October 2021

Abstract
Purpose: Occasionally lumbar spondylolysis in adolescents will recur after conservative treatment. The goal of this study was to retrospectively review the conditions in which recurrence transpired in a subset of adolescent patients diagnosed with acute lumbar spondylolysis. Subjects: A retrospective survey was conducted in 152 patients who had been treated for spondylolysis and had obtained bone union. Twenty subjects were selected who had recurrent lumbar spondylolysis after returning to sports activity following the first spondylolysis treatment. There were 18 males and two females with an average age at the time of initial consultation of 13.3 years and 14.1 years at the time of recurrence.Results: The average period of initial treatment was 101 days, and the average time to recurrence after healing was 149 days. There were three cases at L3, two cases at L4 and 15 cases at L5. At recurrence, 18 patients had unilateral involvement and two patients presented with bilateral occurrence. Four cases did not achieve bony union.Discussion: In this study, the recurrence rate was 13.2%. Eighty percent of cases had recurrence within six months after healing. After recurrence, 20% of the cases reached pseudoarthrosis. It is useful to take regular MRI images to detect recurrence within six months after returning to sports.
Three-dimensional CT Angiography Facilitates Uniportal Thoracoscopic Anatomic Lung Resection for Pulmonary Sequestration
Authors: Zheng Wenlong , Zhang Miao , Wu Wenbin , Zhang Hui , Xinhui Zhang 
Published: October 2021

Abstract
BackgroundPulmonary sequestration (PS) is a rare lesion with independent blood supply from an anomalous systemic artery. A timely resection is considered the best treatment for PS, but the optimal approach is controversial. Three-dimensional computed tomography angiography (3D-CTA) has been widely utilized for precise thoracic surgery. This study aimed to investigate the safety of uniportal video-assisted thoracoscopic surgery (VATS) for PS assisted with preoperative 3D-CTA. MethodsThe data of patents with PS who underwent VATS anatomic lung resection between April 2011 and May 2021 in a single centre were retrospectively reviewed. They were divided into uniportal and tow-port groups according to the initial surgical plan. The perioperative parameters including the incidence of conversion to open thoracotomy, operation time, blood loss, complications and chest tube duration were analyzed. ResultsTwenty consecutive patients (9 in uniportal group and 11 in two-port group) underwent VATS for PS, including 12 female and 8 male patients, with a mean age of 45 years old (range, 24-60 years). Nine cases demonstrated recurrent febrile, cough, or hemoptysis; whereas the other 11 patients were asymptomatic. The 3D-CTA was utilized for all patients in the uniportal group and 1 patient in the two-port group. Eighteen (90.0%) intralobar and 2 extralobar PS were confirmed; and 18 (90.0%) lesions were located in the left thorax. The feeding vessels originated from the thoracic aorta in 16 patients (80.0%), the abdominal aorta in 3 (15.0%) and the inferior phrenic artery in 1 patient (5.0%). Thirteen lobectomies, 5 segmentectomies and 2 mass excisions were performed. There was no major bleeding or 30-day mortality. No conversion was needed in the uniportal group; whereas 6 (54.5%) conversions (4 to multiple-port and 2 to thoracotomy) occurred in the two-port group, indicating a significant difference (P=0.008). In addition, the operation time in the uniportal VATS group was significantly shorter than those in the two-port VATS group ([110.6 ± 25.5] min vs. [148.6 ± 42.1] min, P = 0.029). The other perioperative variables were similar between the two groups. During the follow-up of 5-75 months, no recurrence of hemoptysis was recorded. ConclusionPreoperative 3D-CTA facilitates the safe performance of uniportal VATS anatomic lung resection for PS, which might be associated with shorter operation time and lower conversion to thoracotomy.
Parasitological and Microbiological Investigation of Meat and Offal Consumed in Istanbul
Authors: Dümen Emek , Bilgin Zahide , Tarakçı Nadide Gizem , Ekici Gözde , Sezgin Funda Hatice 
Published: October 2021

Abstract
In this study, it was aimed to explore the presence of some important foodborne parasitological and microbiological parameters that may seriously risk the consumers’ health (total coliform, Staphylococcus aureus, Listeria monocytogenes, Escherichia coli, Escherichia coli EHEC O157:H7, Salmonella spp., Salmonella enteritidis, Salmonella typhimurium and Toxoplasma gondii) in meat and offals that are sold in various sales points in different districts of Istanbul. For this purpose, 400 samples (100 mutton, 100 beef, 100 minced meat and 100 sheep brain) were collected and analyzed by using PCR procedures for aforementioned parameters. The data obtained, were interpreted by statistical methods and binary correlations among the parameters will be exposed. Besides, a risk alligment was formed among the sales points and the products. According to the results, Escherichia coli EHEC O157:H7 and Toxoplasma gondii were determined in any samples. However except the aforementioned parameters all the analyzed microbiological variables were exposed in different samples with different concentrations. The results were verified by real-time PCR procedures. Binary correlation analysis were applied to the positive determined microbiological parameters. The results showed that all the positive determined microbiological parameters were positively correlated with each other. The result of the study showed that applynig good hygien procedures is very important to supply qualified and safe food to the costumers is very improtant in very step of food production chain but especially in the sales points that sell ready to eat foods. Besides, it was concluded that the implementation of effective control / inspections and continious education programs which would be held by related government agencies would be very effective for decreasing the incidence of the foodborne pathogens.
PICO Entity Extraction For Preclinical Animal Literature
Authors: Wang Qianying , Liao Jing , Lapata Mirella , Macleod Malcolm 
Published: October 2021

Abstract
Background: Natural language processing could assist multiple tasks in systematic reviews to reduce workflow, including the extraction of PICO elements such as study populations, interventions and outcomes. The PICO framework provides a basis for the retrieval and selection for inclusion of published evidence relevant to a specific systematic review question, and automatic approaches of PICO extraction have been developed particularly for reviews of clinical trial findings. Considering the difference between preclinical animal studies and clinical trials, developing separate approaches are necessary. Facilitating preclinical systematic reviews will inform the translation from preclinical to clinical research. Methods: We randomly selected 400 abstracts from the PubMed Central Open Access database which described in vivo animal research and manually annotated these with PICO phrases for Species, Strain, model Induction, Intervention, Comparator and Outcome. We developed a two-stage workflow for preclinical PICO extraction. Firstly we fine-tuned BERT with different pre-trained modules for PICO sentence classification. Then, after removing text irrelevant to PICO features, we explored LSTM, CRF and BERT-based models for PICO entity recognition. We also explored a self-training approach because of the small training corpus.Results: For PICO sentence classification, BERT models using all pre-trained modules achieved an F1 score over 80%, and models pre-trained on PubMed abstracts achieved the highest F1 of 85%. For PICO entity recognition, fine-tuning BERT pre-trained on PubMed abstracts achieved an overall F1 of 71%, and satisfactory F1 for Species (98%), Strain (70%), Intervention (70%) and Outcome (67%). The score of Induction and Comparator is less satisfactory, but F1 of Comparator can be improved to 50% by applying self-training. Conclusions: Our study indicates that of the approaches tested, BERT pre-trained on PubMed abstracts is the best for both PICO sentence classification and PICO entity recognition in the preclinical abstracts. Self-training yields better performance for identifying comparators and strains.
Renewable Energy for Long-Term Growth and Development: Bangladesh Perspective
Authors: Jamal Taskin , Fogwill Prof Christopher J. , Bhuiyan Ashraf Hossain 
Published: October 2021

Abstract
Beneficiaries prefer renewable energy-based systems over grid-connected electricity. The cost of energy is viewed as the most influential factor while choosing renewable energy systems. Beneficiaries chose to stay linked with renewa­ble energy systems even when they received grid-connected electricity at a lower tariff.Net-metering and feed-in tariff mechanisms, as well as tax cuts and subsidies for renewable energy projects, could be the catalyst for fostering greater uptake of renewables in the electricity generation mix.
Association of Low-Dose Glucocorticoid Use And Infection Occurrence in Systemic Lupus Erythematosus Patients: A Prospective Cohort Study
Authors: Abe Kazuya , Ishikawa Yuichi , Kita Yasuhiko , Yajima Nobuyuki , Inoue Eisuke , Sada Ken-ei , Miyawaki Yoshia , Yoshimi Ryusuke , Shimojima Yasuhiro , Ohno Shigeru , Kajiyama Hiroshi , Ichinose Kunihiro , Sato Shuzo , Fujiwara Michio 
Published: October 2021

Abstract
Background: Infection is a major cause of mortality in patients with systemic lupus erythematosus (SLE). Therefore, minimizing the risk of infection is an important clinical goal to improve the long-term prognosis of SLE patients. Treatment with ≥7.5 mg prednisolone (PSL) or equivalent has been reported to increase the risk of infections. However, it remains unclear whether <7.5 mg PSL or equivalent dose affects the risk of infection in SLE patients. This study evaluated the association between the occurrence of infection in patients with SLE and low-dose glucocorticoids (GC) usage, especially <7.5 mg PSL or equivalent, to explore the GC dose that could reduce infection occurrence.Methods: This prospective cohort study included patients from the Japanese multicenter registry of patients with SLE (defined as ≥4 American College of Rheumatology 1997 revised criteria) over 20 years of age. The PSL dose was categorized as PSL 0‒2.5, 2.6‒5.0, 5.1‒7.5, and 7.6‒15.0 mg. The primary outcome was infection requiring hospitalization. We conducted a multivariable analysis using time-dependent Cox regression analysis to assess the hazard ratio of infection occurrence compared with a dose of 0‒2.5 mg PSL or equivalent in the other three PSL dose groups. Based on previous reports and clinical importance, the covariates selected were age, sex, and concurrent use of immunosuppressants with GC. In addition, two sensitivity analyses were conducted. 　Results: The mean age of the 509 SLE patients was 46.7 years; 89.0% were female, and 77.2% used multiple immunosuppressants concomitantly. During the 1-year observation period, infection requiring hospitalization occurred in 52 patients. The incidence of infection with a PSL dose of 5.0‒7.5 mg was significantly higher than that in the PSL 0–2.5 mg group (adjusted hazard ratio: 6.80, 95% confidence interval: 2.17‒21.27). The results of the two sensitivity analyses were similar.Conclusions: Our results suggested that the use of 5.0‒7.5 mg PSL or equivalent could pose an infection risk in SLE patients. This finding indicated that PSL dose should be reduced to as low as possible in SLE patients to avoid infection.
The atlas of human cardiac promoters and enhancers reveals an important role for regulatory elements in heart failure
Authors: Deviatiiarov Ruslan , Gams Anna , Syunyaev Roman , Tatarinova Tatiana , Singh Ramesh , Shah Palak , Gusev Oleg , Efimov Igor 
Published: October 2021

Abstract
A continuous increase in the prevalence of heart failure and the lack of adequate therapy highlight poor understanding of the underlying genetic regulatory mechanisms involved in heart failure pathogenesis. Growing evidence has demonstrated a significant contribution of non-coding genome regulatory elements towards transcriptomic changes in heart disease. Thus, there is a pressing need for a comprehensive resource of the human cardiac regulatory network in healthy and failing states. We applied cap analysis of gene expression sequencing to directly measure the expression of RNA associated with enhancers and promoters. Based on this data, we constructed the atlas of transcribed cardiac regulatory elements from 21 healthy and 10 failing (ischemic and non-ischemic cardiomyopathy) human hearts. In total, we have sequenced 109 samples from the left and right atria and ventricles, identifying 17,668 promoters and 14,920 enhancers associated with 14,519 genes. Leveraging this atlas, we provide insights into functional and structural regulatory changes between healthy and failing hearts. Healthy atria and ventricles had distinct pathway enrichment and transcription factor binding patterns, significantly remodeled by heart failure. Using the advantages of deep sequencing that allow effective analysis of cis-regulatory elements-derived RNA, we found that heart failure is associated with the expression of transcripts derived from alternative promoters and a specific set of transcribed enhancers. Furthermore, we identified a high prevalence of single nucleotide polymorphisms associated with cardiovascular diseases within the regulatory regions highlighting their importance in disease pathogenesis. This open-source atlas will serve the cardiovascular community to improve understanding cardiac regulatory network and facilitate the development of novel therapeutics.
The Burden of Childhood Asthma by Age Group, 1990-2019: A Systematic Analysis for Global Burden of Disease Study 2019 Data
Authors: DAOQI ZHANG , Zheng Jinxin 
Published: October 2021

Abstract
Background: Asthma is a common respiratory disease in children. We aimed to update information about incidence of and mortality and disability adjusted life years (DALYs) due to childhood asthma and provide evidence-based recommendations for childhood asthma prevention.Methods Data were obtained from the Global Burden of Disease (GBD) Study, which was conducted from 1990 to 2019 in 204 countries. First, we estimated the incidence, mortality and DALY rates of childhood asthma with a Bayesian meta-regression model. Second, we analyzed the relationship between the sociodemographic index (SDI) and DALYs in different age groups. Third, we studied changes in the trends of the age-standardized DALY rate between 1990 and 2019 by age group, SDI, and risk factors.Results Globally, the numbers of deaths due to and the incidence and DALY rates of childhood asthma were 12.9 thousand (95% UI 10.6 to 15.7), 22 million (95% UI 15 to 31), and 5.1 million (95% UI 3.4 to 7.5) in 2019, representing 65.1% (95% UI 47.6 to 72.4), 5.3% (95% UI 2.6 to 8.8) and 30% (95% UI 18 to 41) decreases from those in 1990, respectively. With the exception of high-SDI regions, the age-standardized DALY rate in all age groups in all SDI regions decreased. In 2019, the age-standardized DALY rate in 1- to 4-year-olds was highest in low-SDI regions, and that of 5- to 19-year-olds was highest in high-SDI regions. In contrast to those in low-SDI regions, children, except those aged 1 to 4 years, in high-SDI regions had a higher risk of DALYs due to asthma. A high body mass index was a stronger risk factor than occupational asthmagens for childhood asthma.Conclusion Our findings provide insights into asthma prevention and treatment through the identification of key factors related to childhood asthma. Children, especially those aged 5 to 14 years, in high-SDI regions should change their eating and lifestyle habits and exercise regularly. Data on additional chronic diseases in children need to be collected to develop better health prevention recommendations.