bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH PROGRESSIVE MUSCLE RELAXATION TERHADAP PENURUNAN KADAR GULA DARAH SEWAKTU PADA PASIEN DIABETES MELLITUS DI PUSKESMAS KELING 1 KABUPATEN JEPARA
Authors: Rusnoto Rusnoto , Prasetyawati Nur Laily 
Published: December 2021

Latar Belakang : Diabetes Melitus merupakan salah satu penyakit degenerative. Terdapat lebih dari 220 juta DM diseluruh dunia pada tahun 2011 dan 80% lebih penderita berada di negara berkembang termasuk Indonesia (Soegondo, 2009). Kurang lebih 5-10% pasien diabetes menderita DMT1, selebihnya sekitar 90-95% pasien diabetes menderita DMT2 (Smeltzer & Bare, 2002). Beberapa faktor yang dapat meningkatkan kejadian DM adalah umur, keturunan, pola makan yang salah, aktivitas fisik kurang gerak, obesitas, stres, dan pemakaian obat-obatan. Salah satu factor yang dapat meningkatkan kejadian DM yaitu stres. Stres yang menetap menimbulkan respon stres berupa aktivasi sistem saraf simpatis dan peningkatan kortisol. Kortisol ini akan meningkatkan konversi asam amino, laktat, dan piruvat di hati menjadi glukosa melalui proses glukoneogenesis, dengan demikian stres akan meningkatkan kadar glukosa darah. Tujuan : Mengetahui pengaruh progressive muscle relaxation terhadap penurunan kadar gula darah sewaktu pada pasien Diabetes Mellitus di Puskesmas Keling 1 Jepara Tahun 2021. Metode : Metode dalam penelitian ini adalah kuasi eksperimen dengan rancangan control group pre-test and post-test. Sampel 50 responden yang terdiri dari kelompok intervensi dan kelompok kontrol. Alat ukur yang digunakan glukometer digital, lembar observasi latihan PMR. Analisis data menggunakan uji wilcoxon. Hasil Penelitian : Hasil analisis uji wilcoxon signed rank test didapatkan bahwa p value = 0,001 (p value < α) maka dapat disimpulkan Ho ditolak dan Ha diterima yang berarti ada pengaruh progressive muscle relaxation terhadap penurunan kadar gula darah sewaktu pada pasien Diabetes Mellitus di Puskesmas Keling 1 Kabupaten Jepara Tahun 2021. Kesimpulan : Ada pengaruh progressive muscle relaxation terhadap penurunan kadar gula darah sewaktu pada pasien Diabetes Mellitus di Puskesmas Keling 1 Kabupaten Jepara Tahun 2021. Dengan penelitian ini diharapkan ada kelanjutan penelitian ini dengan metode lebih baik.
PENGARUH KONSELING TERHADAP PERSEPSI TENTANG KONTRASEPSI IMPLAN DI PUSTU LAWANGAN DAYA PADEMAWU PAMEKASAN
Authors: Rusady Yulia Paramita , Zulaikha Zulaikha 
Published: December 2021

Kontrasepsi merupakan metode untuk menghindari atau mencegah terjadinya kehamilan. Salah satu metode kontrasepsi efektif adalah implant. Berdasarkan hasil survey awal, pengguna implant hanya 2,5%. Hal itu dikarenakan kurangnya konseling dari bidan. Tujuan penelitian ini yaitu untuk mengetahui adanya pengaruh konseling terhadap persepsi tentang kontrasepsi implan di Puskesmas Pembantu Kelurahan Lawangan Daya Kecamatan Pademawu Kabupaten Pamekasan.Desain penelitian ini bersifat survey analitik, berdasarkan waktunya menggunakan cross sectional. Sampelnya adalah sebagian WUS yang tidak mengunakan kontrasepsi sebanyak 279 orang menggunakan teknik sampling probability sampling tipe simple random sampling. Teknik pengumpulan data dengan cara pengisian kuesioner dan cheklist. Uji statistik yang digunakan adalah Chi-Square.Berdasarkan tabulasi silang diketahui bahwa sebagian besar responden yang paham tentang kontrasepsi implant mempunyai persepsi positif yaitu sebanyak 140 responden (55,6 %). Berdasarkan uji statistik Chi-Square didapatkan nilai , dk = 1, X2 hitung = 4,84 > X2 tabel = 3,841, sehingga dapat disimpulkan bahwa H0 ditolak dan H1 diterima, yang berarti terdapat pengaruh konseling terhadap persepsi tentang kontrasepsi implant di Puskesmas Pembantu Kelurahan Lawangan Daya Kecamatan Pademawu Kabupaten Pamekasan. Maka di perlukan upaya dari petugas kesehatan untuk meningkatkan intensitas konseling/temu wicara dengan para WUS sebagai upaya promotif dalam pemakaian kontrasepsi implant.
HUBUNGAN ANTARA KARAKTERISTIK, TINGKAT PENGETAHUAN DAN STIGMA PADA PENDERITA HIV/AIDS
Authors: Simorangkir Takur Lemunson , Sianturi Sondang Ratnauli , Supardi Sudibyo 
Published: December 2021

Pemerintah memiliki target dalam percepatan penanggulangan HIV/AIDS di Indonesia yaitu Zero infeksi baru, zero orang meninggal dengan HIV/AIDS serta zero stigma dan diskriminasi. Stigma terhadap ODHA memiliki dampak yang besar bagi program pencegahan dan penanggulangan HIV/AIDS termasuk kualitas hidup ODHA. Pengetahuan yang baik akan mengurangi stigma yang muncul. Penelitian ini bertujuan untuk mengetahui hubungan tingkat pengetahuan dan stigma pada penderita HIV/AIDS di Jakarta. Jenis penelitian ini adalah kuantitatif dengan desain cross sectional. Sampel pada penelitian ini adalah adalah penderita HIV/AIDS yang berjumlah 93 responden dengan teknik pengambilan sampling yaitu pusposive sampling. Hasil univariat yaitu usia 17-25 tahun sebesar 48,4% dan usia 26-36 tahun 51,6%, pendidikan tinggi 68,8% dan rendah 31,2%, bekerja 48,4% dan tidak bekerja 51,6%, tingkat pengetahuan kurang 66,7%, stigma berat 52,7%. Berdasarkan hasil bivariat diperoleh bahwa hubungan karakteristik dan tingkat pengetahuan yaitu usia dan tingkat pengetahuan dengan nilai p value 0,668, pekerjaan dan tingkat pengetahuan dengan nilai p value 1, pendidikan dan tingkat pengetahuan dengan nilai p value 0,242 yang berarti tidak ada hubungan yang bermakna antara karakteristik dan tingkat pengetahuan. Hubungan tingkat pengetahuan dan stigma dengan nilai p value = 0,463 yang berarti tidak ada hubungan yang bermakna antara pengetahuan dan stigma.
IMPLIKASI COVID-19 PADA PERSALINAN
Authors: Nasriyah Nasriyah , Islami Islami , Asiyah Nor 
Published: December 2021

Covid-19 merupakan penyakit infeksi yang disebabkan oleh virus. Sampai saat ini Covid-19 masih mewabah di seluruh dunia bahkan Indonesia merupakan salah satu Negara yang sangat terdampak oleh virus ini. Dampak yang diakibatkan oleh Covid-19 meluas mulai dari sektor pendidikan, ekonomi dan kesehatan. Covid-19 menular sangat cepat dan menyerang pada semua usia dan kalangan bahkan dapat menyerang pada masa reproduksi yaitu pada ibu hamil, bersalin, nifas dan bayi baru lahir. Meskipun belum ada bukti kuat terkait penularan Covid-19 terhadap ibu hamil dan bersalin, namun pada kenyataannya angka morbiditas dan mortalitas ibu dan bayi akibat Covid-19 cukup tinggi. Hampir dua juta kasus kematian bayi baru lahir terjadi setiap tahunnya, dengan satu kematian bayi setiap 16 detik, demikian menurut laporan Perserikatan Bangsa-Bangsa (PBB). Penelitian ini bertujuan untuk melihat implikasi atau dampak Covid-19 pada persalinan. Metode penelitian menggunakan artikel review dari jurnal. Pencarian jurnal dilakukan sejak tanggal 15-20 Februari 2021 dengan kata kunci Implikasi Covid-19 pada persalinan, referensi yang digunakan sebagai sumber berjumlah 12 jurnal yang diambil dari jurnal PubMed dan Web Page. Beberapa hasil penelitian menunjukkan bahwa ibu bersalin dengan Covid-19 tidak dapat menularkan kepada bayi yang baru saja dilahirkan, tetapi ada beberapa penelitian yang menunjukkan bahwa kehamilan dengan Covid-19 meningkatkan risiko terjadinya persalinan prematur dan persalinan dengan sectio secaria. Untuk mencegah penularan dari ibu ke bayi yang telah dilahirkan maka direkomendasikan untuk menerapkan protokol kesehatan dengan cara melakukan pemisahan ibu dan bayi.
Controlling factors of ecosystem and soil respiration in a xeric shrubland in the Chihuahuan Desert, Mexico
Authors: Flores-Rentería Dulce Yaahid 
Published: December 2021

In the terrestrial carbon cycle is very relevant to identify the influence of soil in the CO2 released to the atmosphere, which is linked to multiple biotic and abiotic drivers. Arid ecosystems dominate the trend and interannual variability of the land CO2 sink. This pattern is mainly controlled by temperature, precipitation, and shortwave radiation. Thus, these environments are characterized by a wide variability of water availability, which causes the CO2 efflux to be highly variable in time, challenging our model capacities. This study aims to understand the ecosystem CO2 fluxes and their controlling mechanisms from the Chihuahuan Desert in Northeast Mexico. We explore the average contribution of the Rsoil (1.30 mmol m-2 s‑1) to Reco (1.76 mmol m-2 s‑1), while identifying the controlling mechanisms of both on an annual scale. The structural equation model constructed showed a good f it for the data, explaining 50% and 93% of the annual variance of Rsoil and Reco, respectively. According to this model, Rsoil was mainly controlled by the air temperature, and Reco by soil water content. Unexpectedly, vapor pressure def icit was the most weight variable with a direct negative effect on Reco, supporting the idea that the vegetation component has a crucial role in the CO2 efflux of this ecosystem. This study highlights the importance of include multiple factors in the models of the C cycle.
Phytoremedial effect of fruit extract of Moringa oleifera on alloxan induced diabetic model in Swiss albino mice
Authors: Kumari Roushan , Singh Arun Kumar , Kumar Ranjit , Kumar Arun 
Published: December 2021

Diabetes is a metabolic disorder and global health issue. It arises because of an absolute or relative insulin deficiency that causes hyperglycemia. The study aimed to assess the antihyperglycemic, hepatoprotective, and renal protective effects of ethanolic fruit extract of Moringa oleifera, on alloxan-induced diabetic mice. Four mice were assigned to each group. Alloxan was injected at the dose of 10mg/kg/body weight intraperitoneally to make the diabetic model in mice. Control and diabetic control mice received drinking water as a placebo, while the diabetic model mice group was administered with ethanolic extract of moringa fruit at the dose of 150mg/kg/bodyweight for 12 weeks. After that, animals were sacrificed, and their blood and tissue samples were collected for biochemical and histopathological examination. The glucose level markedly (p<0.0001) increased many folds in Group I (80.73± 1.24 to 221.5±13.4) and Group II (80.73 ± 1.24 from to 221.9±6.88). The level of insulin markedly (P< 0.0001) decreased in both groups (6.8±0.42 to1.378±0.19) and (6.8±0.42 to1.138±0.08) respectively. Serum hepatic and renal marker enzymes increased in the diabetic group of mice. Glucose level was meaningfully (p<0.0001) decreased in the M. oleifera administered group while serum insulin level significantly (p<0.0001) increased. The level of liver marker enzyme and renal marker also decreased as compared to the diabetic control group. Histopathological study revealed that alloxan treatment caused damage to the liver, kidney, and pancreatic tissues while the M. oleifera administered group exhibited significant improvement in the architecture of the liver, kidney, and pancreas. Hence, M. oleifera has great potential to rejuvenate the damaged tissue and consequently can restore all the serum enzymatic and hormonal parameters.
Presbyopia Management with Diffractive Phakic Posterior Chamber IOL
Authors: Bianchi German R. 
Published: December 2021

Objective: To evaluate safety and refractive efficiency after posterior chamber diffractive implantable phakic contact lens (IPCL) surgery.
Material and Methods: A prospective non-randomized case-series study was performed on 54 myopic eyes of 27 patients who had undergone diffractive IPCL surgery. Corneal endothelial cell density (ECD), central corneal thickness (CCT), intra-ocular pressure (IOP), vault, uncorrected distance (UDVA), spherical equivalent (SE) and defocus curve, were all evaluated twelve months after surgery. The presence of cataracts was evaluated by slit-lamp during a postoperative follow-up.
Results: Mean age was 47 ± 2.62 years-old. Mean SE decreased, from -5.95 ± 2.56 D in a pre-operative stage, to -0.25 ± 0.25 D twelve months after surgery. Achieved UDVA was 20/20 in 24.1% of all cases, 20/25 in 74.1% of them, and 20/32 in all remaining cases. No eyes suffered lost lines of vision. The binocular defocus curve was 0.06 ± 0.05 logMAR for a -3.0 D of defocus; 0.11 ± 0.04 logMAR for a -1.5 D of defocus, and 0.08
± 0.03 logMAR for a 0 D of defocus. Twelve months after surgery, mean ECD had decreased by 1.43 %, whereas mean CCT had increased by 0.06 %, without any significant statistical difference (p = 0.28 and p = 0.93 respectively). No difference (p: 0.86) in the vault was observed at 6 months vs.12 months, as well as between IOP measurements (p = 0.22). There were no non-intra or postoperative complications, and, specifically, no cataracts developed either.
Conclusions: Diffractive IPCL was implanted safely. Corneal endothelial CD, CCT, vault, and IOP remained stable twelve months after surgery. Visual acuity for distance, intermediate and near sight were achieved without spectacles.
Highlights of Advances in Medical Retina from the Virtual World Ophthalmology Congress 2020
Authors: Date Akshay , Nigam Chandni 
Published: December 2021

The World Ophthalmology Congress (WOC) is one of the largest international ophthalmology conferences, taking place every two years. The event this year was the first of its kind, held as a virtual summit due to the Covid-19 pandemic. There were over 2000 talks from world experts, a virtual industry exhibition including free papers, e-posters, live symposia and presentations. Medical retina is a subspecialty in which exciting and innovative advances in research were presented. The topics covered included the use of Conbercept for Polypoidal Choroidal Vasculopathy, Faricimab in Diabetic Macular Oedema and neovascular Age Related Macular Degeneration (nAMD), Brolucizumab, Aflibercept and Port Delivery Systems in nAMD, amongst many others. Medical retina continues to be a rapidly advancing field within ophthalmology with new research findings having great implications for treatment burden and service delivery. This report summaries the highlights of advances within the medical retina subspecialty from free papers in WOC 2020.
Pupillotonia and Adie Syndrome
Authors: Horkovičová Kristína , Popov Ivajlo , Valášková Jela 
Published: December 2021

The aim of the work is to approach the examination of the pupil with a focus on anisocoria, its characteristics and approach to the diagnosis of pupillotonia and Adie's syndrome and its clinical evaluation. Pupil function is important not only in neurophthalmological examination but also in general ophthalmological examination. First of all, we need to know how the reflex arc works in order to be able to exclude or confirm whether the parasympathetic or sympathetic is affected. It is also necessary to know the exact characteristics of the pupil, such as size, shape, placement, function and reaction to light and at close range. Only on this basis can we distinguish pathological features. We do not often encounter this diagnosis, but it is necessary to keep it in mind, especially in the field of neurophthalmology but also in general ophthalmology. We also present three cases of pupilotonia and Adie's syndrome, which we diagnosed at the Department of Ophthalmology, Faculty of Medicine, Comenius University, after the patient himself came by emergency admission or was sent directly to ophthalmology clinic. In the discussion, we present various other diagnoses, where the reflex arc may not be affected, but the pathological pupil is caused by intraocular tumors, general systemic diseases and, last but not least, local therapy or alkaloids.
Transscleral Diode Cyclophotocoagulation in Treatment of Glaucoma
Authors: Farraová Petra , Ondrejková Marta , Demianová Daniela 
Published: December 2021

Cyclodestructive procedures are an alternative of surgical treatment of medically refractory glaucoma.
Aim: To assess efficiency and safety of diode cyclophotocoagulation (CPC).
Methods: Retrospective study included 81 eyes with advanced glaucoma operated with CPC for elevated intraocular pressure (IOP) from January 2017 to January 2019. CPC was performed in retrobulbar anesthesia with contact diode laser FOX (A.R.C. Laser, Germany) of wavelength 810 nm, transsclerally to the ciliary body. Energy settings: intensity 2 W, exposition time 2 s, 18 applications in arc of 360°. Decrease of intraocular pressure was investigated during month 1, 6 and 12 after CPC. Safety was evaluated according to the best corrected visual acuity (BCVA) on Snellen optotypes and number of postoperative complications.
Results: Study on 31 eyes of 24 patients, 21 (68 %) women and 10 (32 %) men, with follow-up during more than 12 months. Mean follow-up time was 19.5 ± 6.1 (from 12 to 29) months. Average age was 75.9 ± 9.2 (56 - 93) years. Indication for CPC was primary open angle glaucoma in 15 eyes (49 %), primary angle closure glaucoma in 6 eyes (19 %) and secondary glaucomas in 10 eyes (32 %). All patients were on therapy of 4 antiglaucomatic drops and 10 of them (32 %) on acetazolamide pills.
IOP before CPC was 25.4 ± 11.0 (13–56) mm Hg. After 1 year IOP decreased to 16.9 ± 6.1 (8–40) mm Hg. Best corrected visual acuity (BCVA) before CPC was 0.39 ± 0.34 (0-1), 1 year after CPC 0.36 ± 0.33 (0-1). 1 year after CPC, 11 eyes (35 %) lost 0.23 ± 0.14 rows. 6 from these (19 %) due to other acquired ocular pathologies.
Hypotony occurred in 6 % and uveitis in 10 % eyes.
Conclusion: CPC is a safe and effective method of lowering IOP.
Recommendations for the Management of Uveitis Associated with Juvenile Idiopathic Arthritis: The Czech and Slovak Adaptation of the Share Initiative
Authors: Malcová Hana 
Published: December 2021

Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in children and uveitis is its most important extra-articular manifestation. Evidence-based recommendations are available only to a limited extent and therefore JIA associated uveitis management is mostly based on physicians’ experience. Consequently, treatment practices differ widely, both nationally and internationally. Therefore, an effort to optimize and publish recommendations for the care of children and young adults with rheumatic diseases was launched in 2012 as part of the international project SHARE (Single Hub and Access Point for Pediatric Rheumatology in Europe) to facilitate clinical practice for paediatricians and (paediatric) rheumatologists.
The aim of this work was to translate published international SHARE recommendations for the diagnosis and treatment of JIA associated uveitis and to adapt them for use in the Czech and Slovak Republics.
International recommendations were developed according to the standard methodology of the European League against Rheumatism (EULAR) by a group of nine experienced paediatric rheumatologists and three experts in ophthalmology. It was based on a systematic literature review and evaluated in the form of an online survey and subsequently discussed using a nominal group technique. Recommendations were accepted if > 80% agreement was reached (including all three ophthalmologists).
A total of 22 SHARE recommendations were accepted: 3 on diagnosis, 5 on disease activity assessment, 12 on treatment and 2 on future recommendations. Translation of the original text was updated and modified with data specific to the czech and slovak health care systems and supplemented with a proposal for a protocol of ophthalmological dispensarization of paediatric JIA patients and a treatment algorithm for JIA associated uveitis.
Conclusion: The aim of the SHARE initiative is to improve and standardize care for paediatric patients with rheumatic diseases across Europe. Therefore, recommendations for the diagnosis and treatment of JIA-associated uveitis have been formulated based on the evidence and agreement of leading European experts in this field.
Visões do vírus
Authors: Arruda Renê , Queiroz Bernardo , R. Silva Thiago 
Published: December 2021

A chegada da pandemia de COVID-19 no início de 2020 criou a necessidade de medidas de proteção para frear a doença. Estas medidas, em especial o isolamento social, contribuíram para que o digital passasse a ser a mediação padrão para grande parte das relações humanas. A intensificação da comunicação e sociabilidade por meios digitais intensificou macroprocessos sociais que já estavam em andamento, como a midiatização, “appficação”, migração do trabalho para as residências (home office), coleta massiva de dados para análise e classificação de pessoas com objetivos comerciais, dentre outros.
Este artigo tem por objetivo analisar alguns dos fenômenos emergentes das interações através de meios de comunicação digitais no contexto da pandemia de COVID-19 a partir de três eixos distintos: vigilância e dataficação; diferenças entre comunicação mediada digitalmente em relação a comunicação presencial; construção de narrativas.
Удосконалення методу динамічної маршрутизації з часовими вікнами автомобільних перевезень сільськогосподарської продукції
Authors: Оліскевич Мирослав , Мастикаш Олександр , Ценюх Ярослав 
Published: December 2021

Стаття присвячена вдосконаленню методу динамічної маршрутизації автомобільних перевезень транспортних засобів. Розглядається дрібногуртова доставка на кільцевих маршрутах магістральної транспортної мережі вантажів, які швидко псуються. Головним критерієм якості перевезення обрано мінімальну гарантовану тривалість доставки вантажів з усієї сукупності замовлень на перевезення. Обмеження стосуються горизонту прогнозування, а також часових вікон на доставку вантажів. Іншим обмеженням є інтенсивність використання автомобільних транспортних засобів. Поставлено вимогу залучення мінімальної кількості автомобільних транспортних засобів із наявних. Зроблено огляд та аналіз відомих методів динамічної маршрутизації, який показав, що при зростанні кількості замовлень, особливо незапланованих, вони стають неефективними за якістю результатів. З’ясовано, що застосування попередньої класифікації є способом, який покращує результат маршрутизації. У цій роботі як класифікаційну ознаку використано сумісність окремих операцій транспортного процесу, які виконуються послідовно, в єдиному потоці. Кожна з таких операцій стосується доставки дрібногуртових вантажів за одним замовленням. Попередня класифікація замовлень на перевезення дає змогу сформувати з них оптимальні кільцеві розвізні або збірні маршрути. Крім того, для планування доставки на кільцевих маршрутах вантажів, які швидко псуються, було вперше застосовано складання розкладу виконання транспортних операцій. Для цього розглядались часові зв’язки, які виникають між кожною парою заданих замовлень на перевезення. На основі вивчених зв’язків побудовано модель у вигляді орієнтованого графа. Впорядкування такого графа дає змогу розробити активний, найменш тривалий розклад виконання транспортного процесу. Такий метод дає змогу застосувати лінійне програмування при пошуку оптимального розкладу та метод гілок і меж при маршрутизації. Динамічні зміни дорожніх і транспортних умов не погіршують якості попередньо виконаної маршрутизації. Було виконано апробацію методики на тестових вхідних даних. Порівняння результатів, отриманих за запропонованим методом і відомим методом границь і меж, показав покращання щонайменше на 11 % показників якості розроблених маршрутів і розкладів.