bluuebunny/crossref_metadata_2025_split huggingface dataset:
NÅR KULTUR KOMMER I VEJEN: Kapitalmøder og kulturforståelser på en international uddannelse i Danmark
Authors: Wilken Lisanne 
Published: August 2021

Over the past 10-15 years internationalisation has become a buzz word in university
education. International institutions as well as national and regional governments
promote international exchange of students and teachers, and universities compete
to attract foreign students. Internationalisation is generally based on the idea of
intercultural compatibility, which implies that ‘scholastic capital’ fairly easily can
be transferred from one university context to another and that educational settings
can promote and benefit from cultural diversity. With reference to a study of one
internationalised educational setting in Denmark, this article explores some of the
less recognised challenges in relation to internationalisation of university education.
Inspired by Pierre Bourdieu’s concept of cultural capital and Gregory Bateson’s
concept of framing, the article argues that the combination of differences in cultural
capital and differences in locally embedded ‘context knowledge’ may produce
obstacles to fruitful intercultural interaction. It argues, moreover, that the interactions
between students are to a large extent based on an unequal relationship
between a home-team and a foreign team rather than on an equal relationship
between different nationalities. The obstacles this creates are, to a large extent,
unacknowledged, because individuals tend to interpret differences as ‘national
differences’.
Ciné-militantisme et nostalgie : le cas brésilien du Cine Vaz Lobo
Authors: Ferraz Talitha , Gouin Alexandre 
Published: August 2021

Cet article explique comment plusieurs dimensions de la nostalgie sont impliquées dans les initiatives de ciné-militantisme pour la préservation et la réouverture d’un ancien cinéma situé dans la banlieue de Rio de Janeiro (Brésil) : le Cine Vaz Lobo. Bien qu’inopérant depuis 1986 et déjà menacé de démolition, ce vieux cinéma art déco des années 1940 se tient toujours au milieu de la réalité socio-économique appauvrie de sa région. Il ne reste du Cine Vaz Lobo qu’une ruine préservée capable de catalyser des souvenirs liés à un passé local marqué par la fréquentation du cinéma, qui représente également un repère qui rassemble les résistances communautaires dans les sphères urbaines et sociopolitiques. La dynamique discursive et les engagements du Movimento Cine Vaz Lobo, le groupe qui lutte pour la survie de ce cinéma, trouvent dans la nostalgie une puissante ressource réflexive et critique, au service des luttes contre l’effacement des aspects identitaires et des relations historiques entre cinémas et villes.
Courir derrière la vérité. Souvenirs, fictions et hantises de la mobilité journalistique chez David Fincher
Authors: Carrier-Lafleur Thomas 
Published: August 2021

À partir de la notion de mobilité, cet article porte sur la représentation du journalisme dans le cinéma de fiction hollywoodien. Toujours à la recherche des nouveaux signes qui pourront faire débloquer son enquête, le journaliste s’inscrit dans une quête où la vérité est tributaire de la mobilité : c’est par le mouvement des corps que l’écheveau du réel se démêle et qu’une forme de vrai commence à apparaître. Il en va de même pour le cinéma pelliculaire, qui repose aussi sur une logique de la trace et de l’indice : le mouvement du réel se réfracte dans l’objectif et s’imprime sur la pellicule. Depuis ses origines, Hollywood a produit des fictions où les héros journalistes, courant derrière la vérité, emblématisent la quête de sens propre au support qui leur donne forme. Or, le cinéma numérique, avec ses nouveaux paradigmes, bouleversera ce rapport entre mobilité journalistique et production analogique du vrai. À partir d’une analyse de deux films de David Fincher qui mettent en scène les différents rouages de l’univers de la presse et du reportage, nous analyserons les mutations de l’imaginaire journalistique et de sa poétique du support à l’ère du numérique.
Red Lines
Authors: George Cherian , Liew Sonny 
Published: August 2021

A lively graphic narrative reports on censorship of political cartoons around the world, featuring interviews with censored cartoonists from Pittsburgh to Beijing.
Why do the powerful feel so threatened by political cartoons? Cartoons don't tell secrets or move markets. Yet, as Cherian George and Sonny Liew show us in Red Lines, cartoonists have been harassed, trolled, sued, fired, jailed, attacked, and assassinated for their insolence. The robustness of political cartooning—one of the most elemental forms of political speech—says something about the health of democracy. In a lively graphic narrative—illustrated by Liew, himself a prize-winning cartoonist—Red Lines crisscrosses the globe to feel the pulse of a vocation under attack.
A Syrian cartoonist insults the president and has his hands broken by goons. An Indian cartoonist stands up to misogyny and receives rape threats. An Israeli artist finds his antiracist works censored by social media algorithms. And the New York Times, caught in the crossfire of the culture wars, decides to stop publishing editorial cartoons completely. Red Lines studies thin-skinned tyrants, the invisible hand of market censorship, and demands in the name of social justice to rein in the right to offend. It includes interviews with more than sixty cartoonists and insights from art historians, legal scholars, and political scientists—all presented in graphic form. This engaging account makes it clear that cartoon censorship doesn't just matter to cartoonists and their fans. When the red lines are misapplied, all citizens are potential victims.
Gender(s)
Authors: Stockton Kathryn Bond 
Published: August 2021

Why gender is strange, even when it's played straight, and how race and money are two of its most dramatic ingredients.
In this volume in the MIT Press Essential Knowledge series, Kathryn Bond Stockton explores the fascinating, fraught, intimate, morphing matter of gender. Stockton argues for gender's strangeness, no matter how “normal” the concept seems; gender is queer for everyone, she claims, even when it's played quite straight. And she explains how race and money dramatically shape everybody's gender, even in sometimes surprising ways. Playful but serious, erudite and witty, Stockton marshals an impressive array of exhibits to consider, including dolls and their new gendering, the thrust of Jane Austen and Lil Nas X, gender identities according to women's colleges, gay and transgender ballroom scenes, and much more.
Stockton also examines gender in light of biology's own strange ways, its out-of-syncness with “male” and “female,” explaining attempts to fortify gender with clothing, language, labor, and hair. She investigates gender as a concept—its concerning history, its bewitching pleasures and falsifications—by meeting the moment of where we are, with its many genders and counters-to-gender. This compelling background propels the question that drives this book and foregrounds race: what is “the opposite sex,” after all? If there is no opposite, doesn't the male/female duo undergirding gender come undone?
Germline mutation analyses of malignant ground glass opacity nodules in non-smoking lung adenocarcinoma patients
Authors: Mao Wenjun , Chen Ruo , Lu Rongguo , Wang Shengfei , Song Huizhu , You Dan , Liu Feng , He Yijun , Zheng Mingfeng 
Published: August 2021

Background
Germline mutations play an important role in the pathogenesis of lung cancer. Nonetheless, research on malignant ground glass opacity (GGO) nodules is limited.

Methods
A total of 13 participants with malignant GGO nodules were recruited in this study. Peripheral blood was used for exome sequencing, and germline mutations were analyzed using InterVar. The whole exome sequencing dataset was analyzed using a filtering strategy. KOBAS 3.0 was used to analyze KEGG pathway to further identify possible deleterious mutations.

Results
There were seven potentially deleterious germline mutations. NM_001184790:exon8: c.C1070T in PARD3, NM_001170721:exon4:c.C392T in BCAR1 and NM_001127221:exon46: c.G6587A in CACNA1A were present in three cases each; rs756875895 frameshift in MAX, NM_005732: exon13:c.2165_2166insT in RAD50 and NM_001142316:exon2:c.G203C in LMO2, were present in two cases each; one variant was present in NOTCH3.

Conclusions
Our results expand the germline mutation spectrum in malignant GGO nodules. Importantly, these findings will potentially help screen the high-risk population, guide their health management, and contribute to their clinical treatment and determination of prognosis.
Dongsha Atoll is an important stepping-stone that promotes regional genetic connectivity in the South China Sea
Authors: Liu Shang Yin Vanson , Green Jacob , Briggs Dana , Hastings Ruth , Jondelius Ylva , Kensinger Skylar , Leever Hannah , Santos Sophia , Throne Trevor , Cheng Chi , Madduppa Hawis , Toonen Robert J. , Gaither Michelle R. , Crandall Eric D. 
Published: August 2021

Background
Understanding region-wide patterns of larval connectivity and gene flow is crucial for managing and conserving marine biodiversity. Dongsha Atoll National Park (DANP), located in the northern South China Sea (SCS), was established in 2007 to study and conserve this diverse and remote coral atoll. However, the role of Dongsha Atoll in connectivity throughout the SCS is seldom studied. In this study, we aim to evaluate the role of DANP in conserving regional marine biodiversity.

Methods
In total, 206 samples across nine marine species were collected and sequenced from Dongsha Atoll, and these data were combined with available sequence data from each of these nine species archived in the Genomic Observatories Metadatabase (GEOME). Together, these data provide the most extensive population genetic analysis of a single marine protected area. We evaluate metapopulation structure for each species by using a coalescent sampler, selecting among panmixia, stepping-stone, and island models of connectivity in a likelihood-based framework. We then completed a heuristic graph theoretical analysis based on maximum dispersal distance to get a sense of Dongsha’s centrality within the SCS.

Results
Our dataset yielded 111 unique haplotypes across all taxa at DANP, 58% of which were not sampled elsewhere. Analysis of metapopulation structure showed that five out of nine species have strong regional connectivity across the SCS such that their gene pools are effectively panmictic (mean pelagic larval duration (PLD) = 78 days, sd = 60 days); while four species have stepping-stone metapopulation structure, indicating that larvae are exchanged primarily between nearby populations (mean PLD = 37 days, sd = 15 days). For all but one species, Dongsha was ranked within the top 15 out of 115 large reefs in the South China Sea for betweenness centrality. Thus, for most species, Dongsha Atoll provides an essential link for maintaining stepping-stone gene flow across the SCS.

Conclusions
This multispecies study provides the most comprehensive examination of the role of Dongsha Atoll in marine connectivity in the South China Sea to date. Combining new and existing population genetic data for nine coral reef species in the region with a graph theoretical analysis, this study provides evidence that Dongsha Atoll is an important hub for sustaining connectivity for the majority of coral-reef species in the region.
Investigation of inhibition effect of daidzein on osteosarcoma cells based on experimental validation and systematic pharmacology analysis
Authors: Zhu Yufan , Yang Zhiqiang , Xie Yuanlong , Yang Min , Zhang Yufeng , Deng Zhouming , Cai Lin 
Published: August 2021

Objective
This study aims to explore the effect of daidzein, which is a natural isoflavone compound mainly extracted from soybeans, on osteosarcoma and the potential molecular mechanism.

Material and Methods
143B and U2OS osteosarcoma cells were treated with gradient concentrations of daidzein, and MTT assay was used to determine the cell proliferation capacity and IC50. Hoechst 33342 staining and Annexin V-FITC/PI detection were used to determine apoptosis. Cell cycle was analyzed by flow cytometry, and migration ability were detected by transwell assays and scratch wound assay. An osteosarcoma xenograft mice model was applied to investigate the effect of daidzein on osteosarcoma in vivo. Systematic pharmacology and molecular modeling analysis were applied to predict the target of daidzein to osteosarcoma, and the target Src was verified by western blotting. We also observed the effect of daidzein on cell proliferation and apoptosis of Src-overexpressing osteosarcoma cells.

Results
In vitro, daidzein significantly inhibited 143B and U2OS osteosarcoma cell proliferation and migration, and induced cell cycle arrest. In vivo, daidzein exerts antitumor effects in osteosarcoma xenograft mice. After systematic screening and analysis, Src-MAPK signaling pathway was predicted as the highest-ranked pathway. Western blot demonstrated that daidzein inhibited phosphorylation of the Src-ERK pathway in osteosarcoma cells. Also, overexpression of Src could partially reverse the inhibitory effects of daidzein on osteosarcoma cell proliferation.

Conclusion
Daidzein exerts an antitumor effect on osteosarcoma, and the mechanism may be through the Src-ERK pathway.
Drug-Coated Balloons for the Treatment of Coronary Artery Disease
Authors: Camaj Anton , Leone Pier Pasquale , Colombo Antonio , Vinayak Manish , Stone Gregg W. , Mehran Roxana , Dangas George , Kini Annapoorna , Sharma Samin K. 
Published: December 2024

ImportanceDrug-coated balloon (DCB) angioplasty has emerged as an alternative to drug-eluting stent (DES) implantation for percutaneous coronary intervention (PCI) in patients with coronary in-stent restenosis (ISR) as well as de novo coronary artery disease.ObservationsDCBs are balloons coated with antiproliferative agents and excipients, whose aim is to foster favorable vessel healing after appropriate lesion preparation. By providing homogeneous antiproliferative drug delivery in the absence of permanent foreign body implantation, DCBs offer multiple advantages over DES, including preservation of vessel anatomy and function and positive vessel remodeling. As such, DCBs have become appealing for treatment of ISR, small-vessel disease, long lesions, simplification of bifurcation procedures, and treatment of diffuse distal disease after recanalization of chronic total occlusions. In addition, patients with high bleeding risk, diabetes, and acute coronary syndrome might also stand to benefit from DCB angioplasty.Conclusions and RelevanceAlthough commercially available in numerous countries now for more than a decade, DCB only recently obtained US Food and Drug Administration approval for the treatment of coronary ISR. Moreover, preliminary results from newer generation devices tested in different clinical scenarios have raised the interest of the international community. Accordingly, an up-to-date review is timely particularly with the anticipated wave of research on the matter. Herein, this review encompasses DCB technologies, their worldwide usage, details on relevant indications, and key procedural aspects of DCB angioplasty.
Outpatient Dermatology Productivity Measures by Patient Race, Sex, and Age
Authors: Orenstein Lauren A. V. , Barbieri John S. , Siira Meron , Borre Ethan , Supapannachart Krittin J. , Viera Eric , Prestwood Courtney Ann , Swerlick Robert , Patzer Rachel E. , Chen Suephy C. 
Published: December 2024

ImportanceClinical productivity measures may incentivize clinical care to specific patient populations and thus perpetuate inequitable care. Before the 2021 Medicare physician fee schedule changes, outpatient dermatology encounters for patients who were younger, female, and races other than White systematically generated fewer work relative value units (wRVUs).ObjectiveTo examine the association of patient race, age, and sex with wRVUs generated by outpatient dermatology encounters after 2021.Design, Setting, and ParticipantsThis multi-institutional cross-sectional study evaluated demographic and billing data for outpatient dermatology encounters across 3 academic dermatology practices. The study compared wRVUs generated by outpatient general dermatology encounters in 6-month periods before and after the 2021 fee schedule updates (March 1 to August 31, 2019, and March 1 to August 31, 2021). Eligibility required an age of 18 years or older and available age, race, and sex data. Data analysis was performed from September 2022 to March 2024.Main Outcomes and MeasuresThe primary outcome was wRVUs generated per encounter.ResultsThis study included 89 656 encounters (47 607 before the 2021 Medicare physician fee schedule update and 42 049 after the update). Across all encounters, the mean (SD) patient age was 56.3 (17.8) years; 55 460 encounters (61.9%) were with female patients and 34 196 (38.1%) were with male patients; and 3457 encounters (3.9%) were with Asian patients, 10 478 (11.7%) with Black patients, 72 894 (81.3%) with White patients, and 2287 (3.2%) with patients of other race or ethnicity (Latino and multiracial). The mean (SD) wRVUs per outpatient dermatology encounter was 1.44 (0.88) before the update and 1.80 (0.99) after (P &amp;lt; .001). After 2021, adjusted analyses demonstrated significantly fewer wRVUs per encounter for female (β, −0.11; 95% CI, −0.13 to −0.10) compared with male patients, and for younger (β, 0.04 [95% CI, 0.04 to 0.05] per 10-year increase in age) compared with older patients. After the update, compared with White patients, visits with Asian patients generated fewer wRVUs (β, −0.12; 95% CI, −0.17 to −0.08) as did visits with Black patients (β, −0.14; 95% CI, −0.17 to −0.11), both statistically significant reductions compared with prior comparisons (P &amp;lt; .001 for both). After 2021, mediation analysis identified that premalignant destructions and biopsies mediated many of the remaining differences in wRVU generation by patient age, race, and sex.Conclusions and RelevanceThis study found that after the 2021 Medicare fee schedule updates, there was a persistent, albeit reduced, gap between wRVU productivity in outpatient dermatology visits for Asian and Black compared with White patients. These persisting differences were attributable to skin biopsies and cryotherapy of premalignant lesions.
Association of State Cannabis Legalization With Cannabis Use Disorder and Cannabis Poisoning
Authors: Jayawardhana Jayani , Hou Jialin , Freeman Patricia , Talbert Jeffery C. 
Published: December 2024

ImportanceWhether state implementation of medical and recreational cannabis laws is associated with increased cannabis use disorder (CUD) and/or cannabis poisoning among adults is not evident.ObjectiveTo examine state-level medical and recreational cannabis laws’ associations with CUD and cannabis poisoning, overall and by sex and age subgroups.Design, Setting, and ParticipantsIn this longitudinal cohort study, state-level CUD and cannabis poisoning diagnoses from January 2011 to December 2021 were examined across all 50 US states and the District of Columbia before and after the implementation of medical and recreational cannabis laws (MCLs and RCLs, respectively) using a staggered adoption difference-in-differences approach. Event studies were conducted to estimate the magnitude of the association for each year-quarter relative to the time of each policy implementation. This study was conducted among all adults aged 18 to 64 years enrolled in the Merative MarketScan Commercial Claims and Encounters Database, a database of employer-sponsored health insurance enrollees, with 1 year or more of continuous enrollment from 2011 to 2021. Data analysis was performed from January to August 2024.ExposuresState implementation of an MCL, opening a medical cannabis dispensary (MCD), allowing home cultivation of medical cannabis (HC-MC), and passage of an RCL.Main Outcomes and MeasuresCUD and cannabis poisoning diagnoses per 100 000 enrollees per quarter.ResultsThis study included 110 256 536 enrollees, of whom 56 843 030 (52%) were female and the mean (SD) enrollee age was 41.0 (13.5) years. MCLs were associated with significant increases in CUD and cannabis poisoning by 31.09 (95% CI, 20.20-41.99; P &amp;lt; .001) and 0.76 (95% CI, 0.52-1.00; P &amp;lt; .001) diagnoses per 100 000 enrollees per quarter, respectively, and RCLs were associated with a significant increase in cannabis poisoning by 0.34 (95% CI, 0.19-0.48; P &amp;lt; .001) per 100 000 enrollees per quarter in states with RCLs compared to states without these laws. No significant associations were observed for MCDs or HC-MC. Relative increases in CUD associated with MCLs were higher among female enrollees and among enrollees aged 35 to 44 years compared with male enrollees and other age groups, respectively. Sensitivity analysis results of 2011 to 2019 data were consistent with the 2011 to 2021 results.Conclusions and RelevanceIn this longitudinal cohort study, MCLs were associated with increased CUD and cannabis poisoning diagnoses, and RCLs were associated with increased cannabis poisoning in adults aged 18 to 64 years with employer-sponsored health insurance. Communities with increased access to cannabis may experience increased health care use and costs due to increases in cannabis poisoning and CUD, and new clinical and policy interventions are needed to curb these rising diagnoses.