bluuebunny/crossref_metadata_2025_split huggingface dataset:
The lifecycle of heuristics as managerial proverbs
Authors: Atanasiu Radu 
Published: June 2021

PurposeThis paper proposes a theory-based process model for the generation, articulation, sharing and application of managerial heuristics, from their origin as unspoken insight, to proverbialization, to formal or informal sharing, and to their adoption as optional guidelines or policy.Design/methodology/approachA conceptual paper is built using systematic and non-systematic review of literature. This paper employs a three-step approach to propose a process model for the emergence of managerial heuristics. Step one uses a systematic review of empirical studies on heuristics in order to map extant research on four key criteria and to obtain, by flicking through this sample in a moving-pictures style, the static stages of the process; step two adapts a knowledge management framework to yield the dynamic aspect; step three assembles these findings into a graphical process model and uses insights from literature to enrich its description and to synthesize four propositions.FindingsThe paper provides insights into how heuristics originate from experienced managers confronted with negative situations and are firstly expressed as an inequality with a threshold. Further articulation is done by proverbialization, refining and adapting. Sharing is done either in an informal way, through socialization, or in a formal way, through regular meetings. Soft adoption as guidelines is based on expert authority, while hard adoption as policy is based on hierarchical authority or on collective authority.Research limitations/implicationsThe findings are theory-based, and the model must be empirically refined.Practical implicationsPractical advice for managers on how to develop and share their portfolio of heuristics makes this paper valuable for practitioners.Originality/valueThis study addresses the less-researched aspect of heuristics creation, transforms static insights from literature into a dynamic process model, and, in a blended-theory approach, considers insights from a distant, but relevant literature – paremiology (the science of proverbs).
Social distancing behavior during COVID-19: a TPB perspective
Authors: Ang Tyson , Wei Shuqin , Arli Denni 
Published: June 2021

PurposeIn responding to the Coronavirus (COVID-19) pandemic, drastic public health measures such as social distancing and lockdowns have been implemented across the globe to slow the spread of the virus. In the USA, the public's reaction to social distancing has been mixed, evident in a high number of people flocking to beaches, bars and shops as coronavirus cases soar. Public health officials have issued strong warnings about the danger people face but the problem persists. To fill this gap, informed by the theory of planned behavior (TPB), this research explores why many people refuse to practice social distancing.Design/methodology/approachTwo studies were conducted during the ongoing COVID-19 pandemic. In the first study, a sample of 750 respondents was recruited from a US online consumer panel to complete a structured survey questionnaire. The data were analyzed using confirmatory factor analysis and structural equation modeling. In the second study, an open-ended questionnaire was administered to 50 US online participants to further uncover people's in-depth perceptions and perspectives toward the pandemic and social distancing. Thematic analysis was used to analyze the data.FindingsThe results from the first study show that risk-taking attitude, authoritarianism and subjective norm are significant predictors of social distancing intention and behavior, through perceived severity of COVID-19. Four themes emerged from the second study, which are consistent with the proposed conceptual framework in the first study.Originality/valueTheoretically, the authors’ findings first contribute to the emerging marketing literature that focuses on creating sustained positive changes and improving the well-being of consumers, communities and societies. Secondly, their findings corroborate with previous findings documented in the social influence literature by showing that during the times of uncertainty and confusion such as COVID-19, social norms (not forced by laws and regulations) play the most critical role in influencing a voluntary, socially beneficial behavior (such as social distancing). Third, this study extends the application of the TPB into the realm of social distancing behavior. The three main components of the TPB, namely attitude, behavioral control and subjective norm, are shown to predict social distancing behavior. Practically, the results of this research have important implications for public health policies on how to encourage positive public health behavior amid pandemics such as COVID-19.
Virtual reference amid COVID-19 campus closure: a case study and assessment
Authors: Garvey Maureen 
Published: June 2021

PurposeThis case study was conducted to assess and make changes to the consortial virtual reference service for the remainder of the period of fully virtual reference (campus closure); a second objective was to consider implications for service design and delivery upon the eventual return to the physical campus.Design/methodology/approachThis paper begins by introducing the institution, reference practices prior to the pandemic and the changes to reference service necessitated by the campus closure. After a literature review of material related to reference and the pandemic, several years of virtual reference service data are analyzed.FindingsThe use of consortial virtual reference service has significantly increased in the pandemic, as demonstrated by questions asked by users and questions answered by librarians. Changes to work practices based on these data have been made.Originality/valueThis work is original in that it relates to the physical closure of the campus due to the pandemic, about which, to date, little has been published specifically concerning the design and delivery of reference services.
Extended full waveform inversion with matching filter
Authors: Li Yuanyuan , Alkhalifah Tariq 
Published: June 2021

ABSTRACTFull waveform inversion has shown its huge potentials in recovering a high‐resolution subsurface model. However, conventional full waveform inversion usually suffers from cycle skipping, resulting in an inaccurate local minimum model. Extended waveform inversion provides an effective way to mitigate cycle skipping. A matching filter between the predicted and observed data can provide an additional degree of freedom to improve the data fitting and avoid the cycle skipping. We extend the search space to treat the matching filter as an independent variable that we use to bring the compared data within a half cycle to obtain the accurate direction of velocity updates. We formulate the objective function using the penalty method by linearly combining a data‐misfit term and a penalty term. The objective function with a reasonable penalty parameter has a larger region of convergence compared to conventional full waveform inversion. We search for the optimal solution over the extended model by updating the matching filter and the velocity in a nested way. The normalization of the data can bring us an equivalent normalization to the filter and a more effective convergence. In the synthetic Marmousi model, the proposed inversion method recovers the velocity model stably and accurately starting from a linearly increasing model in the case of lack of low frequencies below 3 Hz, in which conventional full waveform inversion suffers from cycle skipping. We also use a marine field data to demonstrate the effectiveness and practicality of the proposed method.
Lanthanide ion (Ln3+)‐based upconversion sensor for quantification of food contaminants: A review
Authors: Rong Yawen , Hassan Md Mehedi , Ouyang Qin , Chen Quansheng 
Published: June 2021

AbstractThe food safety issue has gradually become the focus of attention in modern society. The presence of food contaminants poses a threat to human health and there are a number of interesting researches on the detection of food contaminants. Upconversion nanoparticles (UCNPs) are superior to other fluorescence materials, considering the benefits of large anti‐Stokes shifts, high chemical stability, non‐autofluorescence, good light penetration ability, and low toxicity. These properties render UCNPs promising candidates as luminescent labels in biodetection, which provides opportunities as a sensitive, accurate, and rapid detection method. This paper intended to review the research progress of food contaminants detection by UCNPs‐based sensors. We have proposed the key criteria for UCNPs in the detection of food contaminants. Additionally, it highlighted the construction process of the UCNPs‐based sensors, which includes the synthesis and modification of UCNPs, selection of the recognition elements, and consideration of the detection principle. Moreover, six kinds of food contaminants detected by UCNPs technology in the past 5 years have been summarized and discussed fairly. Last but not least, it is outlined that UCNPs have great potential to be applied in food safety detection and threw new insight into the challenges ahead.
Characterization of peptides with antioxidant activity and antidiabetic potential obtained from chickpea (Cicer arietinum L.) protein hydrolyzates
Authors: Quintero‐Soto María F. , Chávez‐Ontiveros Jeanett , Garzón‐Tiznado José A. , Salazar‐Salas Nancy Y. , Pineda‐Hidalgo Karen V. , Delgado‐Vargas Francisco , López‐Valenzuela José A. 
Published: June 2021

AbstractAlcalase hydrolyzates were prepared from the albumin (AH) and globulin (GH) fractions of eight chickpea (Cicer arietinum L.) genotypes from Mexico and 10 from other countries. Protein content, antioxidant activity (AA) (ABTS, DPPH), and degree of hydrolysis were evaluated and the best genotype was selected by principal component analysis. The hydrolyzates of the chosen genotype were analyzed for its antidiabetic potential measured as inhibition of α‐amylase, α‐glucosidase, and dipeptidyl peptidase‐4 (DPP4). Peptide profiles were obtained by liquid chromatography‐mass spectrometry (UPLC‐DAD‐MS), and the most active peptides were analyzed by molecular docking. The average antioxidant activity of albumin hydrolyzates was higher than that of globulin hydrolyzates. ICC3761 was the selected genotype and peptides purified from the albumin hydrolyzate showed the best antioxidant activity and antidiabetic potential (FEI, FEL, FIE, FKN, FGKG, and MEE). FEI, FEL, and FIE were in the same chromatographic peak and this mixture showed the best ABTS scavenging (78.25%) and DPP4 inhibition (IC50 = 4.20 µg/ml). MEE showed the best DPPH scavenging (47%). FGKG showed the best inhibition of α‐amylase (54%) and α‐glucosidase (56%) and may be a competitive inhibitor based on in silico‐predicted interactions with catalytic amino acids in the active site of both enzymes. These peptides could be used as nutraceutical supplements against diseases related to oxidative stress and diabetes.Practical ApplicationThis study showed that chickpea protein hydrolyzates are good sources of peptides with antidiabetic potential, showing high antioxidant activity and inhibition of enzymes related to carbohydrate metabolism and type 2 diabetes. These hydrolyzates could be formulated in functional foods for diabetes.
Systematic review and meta‐analysis on prevalence of metabolic syndrome in psoriatic arthritis, rheumatoid arthritis and psoriasis
Authors: Loganathan Aravinthan , Kamalaraj Narainraj , El‐Haddad Carlos , Pile Kevin 
Published: June 2021

AbstractBackgroundPsoriatic arthritis (PsA), rheumatoid arthritis (RA) and psoriasis (PsO) are associated with systemic inflammation and increased cardiovascular mortality and morbidity. Metabolic syndrome (MetS) is associated with systemic inflammation, and conditions associated with MetS, such as obesity, are associated with difficulty in attaining minimal disease activity (MDA) in individuals with inflammatory arthritis. This systematic review aims to determine whether there is an increased prevalence of MetS in PsA populations compared with PsO and RA populations.MethodsA systematic review was conducted to assess the prevalence of MetS in PsA, PsO, and RA populations following Preferred Reporting Items for Systematic Reviews and Meta‐analyses guidelines. The quality of the studies reviewed was assessed using the Joanna Briggs Institute Checklist for Prevalence Studies.ResultsThe pooled prevalence of MetS in PsA populations was 0.46 ± 0.06 (95% CI 0.40‐0.51). In comparison, the prevalence of MetS in PsO and RA populations was 0.34 ± 0.03 (95% CI 0.32‐0.37) and 0.31 ± 0.04 (95% CI 0.27‐0.35), respectively. Patients with PsA were 1.62 ± 0.036 (95% CI 1.50‐1.74) and 1.66 ± 0.038 (95% CI 1.54‐1.79) times more likely to have MetS compared with PsO and RA populations.ConclusionThe prevalence of MetS is significantly increased in PsA populations compared with PsO and RA populations. Further studies should be performed using a standardized definition of MetS in PsA, RA, and PsO populations to determine whether addressing the metabolic components in MetS offers any therapeutic benefits and in terms of attaining MDA and improving cardiovascular health.
Silencing LINC01116 suppresses the development of lung adenocarcinoma via the AKT signaling pathway
Authors: Shang Bin , Li Zhenxiang , Li Meng , Jiang Shujuan , Feng Zhen , Cao Zhixin , Wang Hui 
Published: June 2021

AbstractBackgroundA growing body of evidence has proven that long noncoding ribonucleic acids (lncRNAs) are important epigenetic regulators that play crucial parts in the pathogenesis of human cancers. Previous studies have shown that long intergenic nonprotein coding RNA 01116 (LINC01116) is a carcinogen in several carcinomas; however, its function in lung adenocarcinoma (LUAD) has not been clarified. Here, we aimed to investigate the role of LINC01116 in LUAD.MethodsThe relative expression levels of LINC01116 in LUAD cell lines and tissues were detected by quantitative reverse transcription polymerase chain reaction. A Kaplan–Meier survival analysis was performed using patient information from the Gene Expression Profiling Interactive Analysis (GEPIA) database. LUAD proliferation, invasion, migration, and apoptosis were measured by performing cell counting kit‐8, colony formation, transwell, wound healing, and flow cytometric assays. A xenograft animal experiment was performed to investigate the effect of LINC01116 in vivo. Protein kinase B (AKT) signaling pathway‐related protein expressions were tested by Western blot assay.ResultsLINC01116 expression was upregulated in LUAD cells and tissues. The loss‐of‐function experiments on LUAD cells revealed that silencing LINC01116 expression could decrease cell viability both in vitro and in vivo. Furthermore, silencing LINC01116 inhibited LUAD cell invasion and migration and induced cell apoptosis. Mechanically, silencing LINC01116 significantly decreased p‐AKT protein levels, and an AKT pathway stimulator could rescue the suppressive effects of small interfering LINC011116‐specific RNAs on LUAD development.ConclusionsOur study demonstrated that silencing LINC01116 suppresses the development of LUAD via the AKT signaling pathway.
Metabolipidomic profiling reveals an age‐related deficiency of skeletal muscle pro‐resolving mediators that contributes to maladaptive tissue remodeling
Authors: Markworth James F. , Brown Lemuel A. , Lim Eunice , Castor‐Macias Jesus A. , Larouche Jacqueline , Macpherson Peter C. D. , Davis Carol , Aguilar Carlos A. , Maddipati Krishna Rao , Brooks Susan V. 
Published: June 2021

AbstractSpecialized pro‐resolving mediators actively limit inflammation and support tissue regeneration, but their role in age‐related muscle dysfunction has not been explored. We profiled the mediator lipidome of aging muscle via liquid chromatography‐tandem mass spectrometry and tested whether treatment with the pro‐resolving mediator resolvin D1 (RvD1) could rejuvenate the regenerative ability of aged muscle. Aged mice displayed chronic muscle inflammation and this was associated with a basal deficiency of pro‐resolving mediators 8‐oxo‐RvD1, resolvin E3, and maresin 1, as well as many anti‐inflammatory cytochrome P450‐derived lipid epoxides. Following muscle injury, young and aged mice produced similar amounts of most pro‐inflammatory eicosanoid metabolites of cyclooxygenase (e.g., prostaglandin E2) and 12‐lipoxygenase (e.g., 12‐hydroxy‐eicosatetraenoic acid), but aged mice produced fewer markers of pro‐resolving mediators including the lipoxins (15‐hydroxy‐eicosatetraenoic acid), D‐resolvins/protectins (17‐hydroxy‐docosahexaenoic acid), E‐resolvins (18‐hydroxy‐eicosapentaenoic acid), and maresins (14‐hydroxy‐docosahexaenoic acid). Similar absences of downstream pro‐resolving mediators including lipoxin A4, resolvin D6, protectin D1/DX, and maresin 1 in aged muscle were associated with greater inflammation, impaired myofiber regeneration, and delayed recovery of strength. Daily intraperitoneal injection of RvD1 had minimal impact on intramuscular leukocyte infiltration and myofiber regeneration but suppressed inflammatory cytokine expression, limited fibrosis, and improved recovery of muscle function. We conclude that aging results in deficient local biosynthesis of specialized pro‐resolving mediators in muscle and that immunoresolvents may be attractive novel therapeutics for the treatment of muscular injuries and associated pain in the elderly, due to positive effects on recovery of muscle function without the negative side effects on tissue regeneration of non‐steroidal anti‐inflammatory drugs.
Index depressive episode and antidepressant exposure were associated with illness characteristics of pediatric bipolar disorder
Authors: Inal Neslihan , Ermis Cagatay , Koc Dogukan , Aksoy Sena , Karacetin Gul , Tuncturk Mustafa , Eray Safak , Karabina Berna , Faruk Akca Omer , Ozgul Dilek , Gunay Kilic Birim , Cikili Uytun Merve , Besenek Mert , Kavurma Canem , Bilac Oznur , Gokcen Cem , Topal Zehra , Percinel Yazıcı Ipek , Sapmaz Sermin Yalin , Ozyurt Gonca , Diler Rasim Somer 
Published: June 2021

AbstractObjectivePediatric bipolar disorder (PBD) is a serious, recurrent disorder leading to severe functional impairment. As a first mood episode, index episode could affect the long‐term course of the illness. This study aimed to investigate the clinical characteristics of youth with PBD from our multicenter, nationwide, naturalistic follow‐up samples and to identify (i) the effects of index mood episode and (ii) the effect of previous antidepressant treatments on the age at mania onset of PBD.MethodThe study sample consisted of 271 youth with BD‐I followed by the child and adolescent psychiatry clinics of seven different university hospitals and three research state hospitals, representing six geographic regions across Turkey. All diagnoses were made according to structured interviews, and all data were retrospectively obtained from clinical records by the clinicians.ResultsWhen patients with index depressive/mixed episodes (IDE, n=129) and patients with index (hypo)manic episodes (IME, n=142) were compared, the total number of mood episodes and rapid cycling feature were significantly higher in the IDE group than in the IME group. The Cox regression analysis adjusted for sociodemographic and illness characteristics revealed female adolescents in the IDE group treated with antidepressants were more likely to have an earlier onset of mania (hazard ratio=2.03, 95% confidence interval=1.31–3.12, p=0.001).ConclusionThis is the first large‐scale nationwide follow‐up study in Turkey that indicated prior antidepressant treatments were associated with an earlier onset of mania in youth, particularly in adolescent females. Larger prospective studies are needed to identify neurodevelopmental processes underlying PBD and initiate prevention approaches.
Socio‐economic impacts of zero and reduced tillage in wheat fields of the Moroccan drylands
Authors: Yigezu Yigezu A. , El‐Shater Tamer 
Published: June 2021

AbstractZero tillage (ZT) is recommended for dryland farming because it enhances retention of residual soil moisture. However, it is not always clear whether this translates to an economic advantage over conventional tillage, which helps in controlling weeds. Using a nationally representative sample of 1901 wheat fields in Morocco as a case study, we provide comparative analysis on different tillage intensities. Results from an endogenous switching regression model showed that fields that were not tilled gave 298.6 kg/ha (23%) higher yields, US$89/ha (27%) more income and more stable yields than those tilled once or more. Fields that were not tilled also had 87% lower yield variance with 100% and 65.6% less risk of giving yield levels below 500 and 1000 kg/ha, respectively. The highest yield losses occurred during the first and third tillage passes, but the second had negligible effect. Labor saving from avoiding tillage under ZT was undermined by higher labor needed for weeding. Along with biophysical benefits documented elsewhere, our results show that, if constraints for its wider diffusion are removed, zero or reduced tillage has the potential to sustainably improve the economic and biophysical viability of dryland agriculture in Morocco and other similar countries in North Africa and West Asia.