bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intrauterine Cleaning after Placental Delivery at Cesarean Section: A
Systematic Review and Meta-Analysis
Authors: Doosti Rana , Mohammad-Alizadeh-Charandabi Sakineh , Ahmadpour Parivash , Mirghafourvand Mojgan 
Published: February 2021

Introduction:
The increasing rate of cesarean section and its greater number of complications
compared to vaginal childbirth invoke efforts to reduce perioperative complications through
evidence-based techniques.

Objective:
The present study mainly aims to assess the effect of intrauterine cleaning after
placental delivery in the cesarean section on the frequency of endometritis (primary outcome)
and postpartum hemorrhage (secondary outcome).

Material and Methods:
In this systematic review we have followed Preferred Reporting Items
for Systematic Reviews and Meta-Analyses (PRISMA) guideline. Both English and Persian
databases were searched (with no time limit) for clinical trials and quasi-experimental studies
that had investigated the effect of intrauterine cleaning after placental delivery in the cesarean
section on the frequency of endometritis and hemorrhage compared to a control group (no
intrauterine cleaning).

Results:
The meta-analysis on three clinical trials with 696 participants showed no significant
difference between intervention and control groups in the frequency of endometritis (RR= 1.33;
95% CI: 0.74 to 2.41; P= 0.34) and postpartum hemorrhage (RR= 1.06; 95% CI: 0.55 to 2.06;
P= 0.86).

Conclusions:
Based on the meta-analysis results, intrauterine cleaning after placental delivery
in the cesarean section does not affect endometritis and postpartum hemorrhage. Further and
more robust studies based on the Consort Declaration are required to investigate this method
to be recommended for use in clinical practice.
Anti-Tumor Efficacy of Pyrvinium Pamoate Nanoliposomes in an Experimental Model of Melanoma
Authors: Hatamipour Mahdi , Jaafari Mahmoud R. , Zangui Mahtab , Shakour Neda , Sahebkar Amirhossein 
Published: February 2021

Background:
Pyrvinium Pamoate (PP) is an old drug approved by the FDA for the treatment of pinworm
infections. Recently, it has been introduced as an anti-tumor agent, however, low aqueous solubility
severely limits its potential effects. In this study, we developed a liposomal formulation of pyrvinium pamoate
to investigate its in vitro cytotoxicity and in vivo efficacy against melanoma cells.

Materials & Methods:
As drug carriers, liposomes were fabricated using the thin-film method. PP was encapsulated
within the liposomes using a remote loading method. We evaluated the morphology, particle size, and Zeta
potential of the liposomes. Additionally, High-Performance Liquid Chromatography (HPLC) was employed
for qualitative and quantitative analysis. Then we investigated our liposomal PP for its in vitro cytotoxicity as
well as the tumor growth inhibition in C57BL/6 mice bearing B16F0 melanoma tumors.

Results:
Based on the analytical result, the liposomal drug delivery system is a homogeneous and stable colloidal
suspension of PP particles. The images of Atomic force microscopy and particle size data showed that all
the prepared nanocarriers were spherical with a diameter of approximately 101 nm. According to both in vitro
and in vivo studies, nanoliposomal PP exhibited an improved anti-proliferative potential against B16F10 melanoma
tumor compared to free PP.

Conclusion:
Liposomal encapsulation improves the water solubility of PP and enhances its anti-cancer activity.
Methicillin-Resistant Staphylococcus haemolyticus Displaying Reduced
Susceptibility to Vancomycin and High Biofilm-Forming Ability
Authors: Dier-Pereira Ana Paula , Trevizani Thihara Isabella Ramos , Duarte Felipe Crepaldi , da Silva Raquel Soares , Santos Jussevania Pereira , Tavares Eliandro Reis , de Oliveira Caio Ferreira , Pinge-Filho Phileno , Kerbauy Gilselena , Perugini Márcia Regina Eches , Yamauchi Lucy Megumi , Yamada-Ogatta Sueli Fumie 
Published: February 2021

Background:
Staphylococcus haemolyticus is one of the most frequently coagulasenegative
staphylococci isolated from healthcare-associated infections, mainly those related to implanted
medical devices.

Objectives:
This study aimed to determine the antimicrobial susceptibility profile and biofilm
forming capacity of S. haemolyticus isolated from bloodstream infections.

Methods:
A total of 40 S. haemolyticus isolates were characterized according to their genetic relatedness
by repetitive element sequence based-PCR (REP-PCR), antimicrobial susceptibility profile,
SCCmec typing, ability to form biofilm on abiotic surface and occurrence of putative genes related
to biofilm formation.

Results:
One S. haemolyticus was susceptible to all antimicrobials. The other isolates (n=39)
were resistant to cefoxitin; and among them 34 (87.2%) harbored the mecA gene into the SCCmec
type I (5.9%), type III (29.4%), type IV (5.9%) and type V (20.6%); and 38.2% isolates
were designated as NT. Apart from cefoxitin, 94.9% of the isolates were resistant to at least four
antimicrobial classes, and 32.5% displayed minimal inhibitory concentration (MIC) values higher
than 4.0 μg/mL for vancomycin. All isolates formed biofilm on polystyrene surface and were
classified as strong biofilm-producers, except for one isolate. All isolates were negative for icaA
gene, and the prevalence of the other genes was as follows: atl, 100%; fbp, 92.5%; aap, 90.0%;
and bap, 20.0%.

Conclusion:
This study reports a high prevalence of methicillin-resistant S. haemolyticus displaying
decreased susceptibility to vancomycin with the ability to form strong biofilms on abiotic surface.
The results support the importance of controlling the adequate use of antimicrobials for the
treatment of staphylococcal infections.
A Patent Data Analysis in Nanotechnology Applied to Essential Oils
Authors: Oliveira Tainara Santos , de Lima Silva Vanessa , Assunção Larissa Santos , de Jesus Freitas Tayane , Machado Bruna Aparecida Souza , Otero Deborah Murowaniecki , Nunes Itaciara Larroza , de Castro Almeida Rogeria Comastri , Ribeiro Camila Duarte Ferreira , Druzian Janice Izabel 
Published: February 2021

Background:
Essential oils (EOs) are natural substances that serve as sources of bioactive compounds with antioxidant and antimicrobial properties.

Objective:
This prospecting aimed to understand intellectual property related to patent documents on EOs and nanotechnology.

Methods and Results:
The nanotechnology growth curve applied to EOs demonstrated that the period from 2015 to 2017 was the most prominent, with a peak in 2016. China is the dominant country, mainly through research developed in the academic area. The food industry area had the highest number of patents filed, highlighting the preservation line. Ginger essential oil, chitosan and Tween 80 were preferentially used as a core, wall material and an emulsifier, respectively. In the market, the use of EOs is more associated with the pharmaceutical/cosmetics industry. In addition, the food industry market is betting more on products based on hemp oil nanocapsules.

Conclusion:
EO nanotechnology is promising for the development of sustainable food systems. However, this nanotechnology in Brazil has not yet advanced enough in the food industry, although there are government incentives that may change this paradigm in the future. The profile of the patent documents and the products in the market differ between the application and the types of oils. In addition, there is a gap between the volume of patent documents investigated and the transfer of technology to the commercial sector, but this constitution could be better explored, given the properties of EOs.
Metal Nanoparticles in Dye Wastewater Treatment – Smart Solution for Clear Water
Authors: Kerkez Djurdja , Bečelić-Tomin Milena , Gvoić Vesna , Dalmacija Božo 
Published: February 2021

Background:
In past years, nanomaterials have been actively studied and developed
and successfully used in many fields. Due to water scarcity, the application of nanomaterials in
water and wastewater treatment has drawn significant attention. Due to their superior features,
they represent functional materials with great potential for pollution removal and environmental
applications.

Objective:
This literature review aims to summarize and present the metal nanoparticles used for
dye wastewater treatment. The discussion subject is metallic nanoparticles for mentioned use,
with a special focus on iron-based, bimetallic, and photocatalytic nanomaterials.

Methods:
Reference search of “metal nanoparticles in dye wastewater treatment” was conducted
in detail through the Serbian Library Consortium for Coordinated Acquisition (KoBSON). Published
papers search was mainly based on Web of Science and ScienceDirect database focusing
on the latest research on this topic. The corresponding literature was carefully read, analyzed, and
evaluated.

Results:
Two hundred and twenty-four scientific and review articles, thesis, and book chapters,
patents were evaluated in order to summarise current trends in metal nanoparticle use in
wastewater treatment. An increasing trend in scientific research regarding metal nanoparticles can
be observed for the removal of different inorganic and organic pollutants. Among the most extensively
tested are dye molecules, representing challenging species in terms of degradation and consequent
removal. Modification, layering, combination, and green synthesis of metal nanoparticles
result in materials capable of efficient and environmentally sustainable wastewater treatment.

Conclusion:
In this paper, extensive review of metal nanoparticles in dye wastewater treatment is presented. With rapid water demand, development of sustainable materials and technology is necessary. Use of these materials represents eco-friendly, energy efficient and sustainable water purification solution. However, matter of usage commercialization is still to be addressed.
Evaluating the Risk of Covid-19 Transmission from Conjunctival and Lacrimal Discharge: A Review
Authors: Sanyal Shalini , Law Sujata 
Published: February 2021

:
The ocular surface, which is constantly exposed to the external environment, is one of
the most sensitive zones and any complications which have a detrimental impact on it leading to reduced
vision and/or blindness, severely impact the quality of life. The most commonly afflicted
parts of the eye are the conjunctiva, eyelid, and cornea due to their position. Since the eye is moderately
susceptible to microbial infection from bacteria, fungi or even viruses; there has been much
speculation about whether or not the novel coronavirus-2 (SARS-CoV-2) can lead to ocular disorders.
Given the high rate of transmission for this disease, it is of great importance to evaluate the
risk of disease communication from the eye, such as by conjunctival and/ lacrimal discharge.

:
While there are many articles on the topic exploring the ocular aspect of COVID-19/ SARS-CoV-2
infection; there is a significant volume of data that may or may-not seem contradictory at first
glance. This is primarily due to the still-emerging nature of this disease and new data that is being
unearthed every day. The problem is compounded by the fact that despite the over-all concordance,
the different clinical teams have varying diagnostic criteria. This review attempts to consolidate the
data available thus far regarding the risk of COVID-19 transmission from conjunctival/lacrimal
discharge apart from the known modes of transmission, thereby allowing us to speculate whether
additional protective measures are required to combat the zoonotic coronavirus pandemic currently
ravaging the world.
The competence of the full jurisdiction to settle administrative contracts disputes
Authors: Hama Zana Rauf , Muhammad Rasheed Awaz Khalid 
Published: February 2021

As general rule countries that have dual judiciary system, have allocated a specialized judiciary to look into administrative disputes, including administrative contract disputes, and gives full jurisdiction to the judiciary without the mandates of cancellation. The reference of the full jurisdiction of the judiciary in administrative contract disputes is a form of the personal judiciary, where the dispute revolves around an assault or threat to attack a personal legal position of the contestant, and it aims to contest the self-legal acts that affect the acquired rights, and then the reference for disputes related to the contract is the jurisdiction of the judiciary The complete matter commensurate with the nature of these disputes regarding their association with the acquired rights of individuals.
Digital Health Solutions to Control the COVID-19 Pandemic in Countries With High Disease Prevalence: Literature Review
Authors: R Niakan Kalhori Sharareh , Bahaadinbeigy Kambiz , Deldar Kolsoum , Gholamzadeh Marsa , Hajesmaeel-Gohari Sadrieh , Ayyoubzadeh Seyed Mohammad 
Published: February 2021

Background
COVID-19, the disease caused by the novel coronavirus SARS-CoV-2, has become a global pandemic, affecting most countries worldwide. Digital health information technologies can be applied in three aspects, namely digital patients, digital devices, and digital clinics, and could be useful in fighting the COVID-19 pandemic.

Objective
Recent reviews have examined the role of digital health in controlling COVID-19 to identify the potential of digital health interventions to fight the disease. However, this study aims to review and analyze the digital technology that is being applied to control the COVID-19 pandemic in the 10 countries with the highest prevalence of the disease.

Methods
For this review, the Google Scholar, PubMed, Web of Science, and Scopus databases were searched in August 2020 to retrieve publications from December 2019 to March 15, 2020. Furthermore, the Google search engine was used to identify additional applications of digital health for COVID-19 pandemic control.

Results
We included 32 papers in this review that reported 37 digital health applications for COVID-19 control. The most common digital health projects to address COVID-19 were telemedicine visits (11/37, 30%). Digital learning packages for informing people about the disease, geographic information systems and quick response code applications for real-time case tracking, and cloud- or mobile-based systems for self-care and patient tracking were in the second rank of digital tool applications (all 7/37, 19%). The projects were deployed in various European countries and in the United States, Australia, and China.

Conclusions
Considering the potential of available information technologies worldwide in the 21st century, particularly in developed countries, it appears that more digital health products with a higher level of intelligence capability remain to be applied for the management of pandemics and health-related crises.
Salud financiera en créditos hipotecarios mexicanos
Authors: Olivares-Aguayo Héctor Alonso , Méndez-Molina Maivelin , Madrigal-Castillo Eduardo 
Published: February 2021

Si se desea adquirir un patrimonio familiar, la adquisición de crédito hipotecario conlleva una gran responsabilidad y un análisis previo, , pues la persona debe tener muy claras las condiciones y los factores que influyen cuando las entidades hipotecarias privadas, como las instituciones bancarias, o públicas, como el Instituto del Fondo Nacional de la Vivienda para los Trabajadores (INFONAVIT) y el Fondo de la Vivienda del Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado (FOVISSSTE) le otorguen el crédito. El principal riesgo se presenta en no poder cumplir con el pago delos intereses periódicos debido al bajo salario mensual que percibe el cliente. El objetivo de este artículo es examinar la salud financiera en créditos hipotecarios mexicanos - públicos y privados - a partir de un estudio de mercado con datos reales del 2015. El método empleado fue cuantitativo experimental y la metodología usada fue de amortización con periodicidad de pagos mensuales. El principal hallazgo de esta investigación se dio a través de evidencia empírica, donde se mostró que la población de clase media baja puede tener un alto riesgo de incumplimiento en sus créditos hipotecarios, dado a que su ingreso mensual va desde $2103 MXN hasta $6309 MXN. Por este motivo, la investigación buscó dar a conocer a este tipo de población los factores de riesgo a la hora de adquirir un crédito hipotecario. La conclusión es que únicamente en cuatro escenarios analizados, donde el interés total a pagar es menor al 50 % del valor de la propiedad, el cliente debe destinar al pago de su crédito hipotecario la cantidad de $10 000 MXN que, a marzo de 2015, equivalía aproximadamente a 4.75 salario mínimo vigente en el Distrito Federal (SMVDF).
Challenges to Experimental Audit JDM Research and the Role of Online Platforms in Resolving These Challenges
Authors: Leiby Justin , Rennekamp Kristina , Trotman Ken T. 
Published: February 2021

SUMMARY
We survey experienced experimental researchers to understand their beliefs about the biggest challenges facing audit JDM research. By far, the biggest challenge identified by respondents is access to experienced participants. This creates a major problem as examining important research questions often requires hard-to-access professionals, and the availability of these participants has decreased over time. Other important challenges to audit JDM research include the publication process (including demands for multiple experiments in a single study involving experienced participants) and demonstrating practical contributions. We also compare responses about the challenges facing financial and managerial accounting researchers, in order to better understand the problems that are unique to audit researchers. We discuss how the challenges identified might be either mitigated or exacerbated by the use of various online platforms. We discuss data quality issues and potential solutions, provide suggestions on potential new sources of participants, and possible ways forward for audit JDM research.
Mandatory Internal Control Audits, Audit Adjustments, and Financial Reporting Quality: Evidence from China
Authors: Lennox Clive S. , Wu Xi 
Published: February 2021

ABSTRACT
This study examines whether audit adjustments are a mechanism that links the effect of mandatory internal control audits (MICAs) on financial reporting quality. We argue that the requirement for auditors to publicly disclose internal control weaknesses exacerbated auditor-client conflicts and that this resulted in auditors being less likely to detect (and correct) misstatements in their clients' pre-audit financial statements. Consistent with this argument, we find significant reductions in audit adjustments following the staggered introduction of MICAs using data from China. We find the reductions in audit adjustments are associated with significant increases in material misstatements following the introduction of MICAs. In contrast, we find that the introduction of MICAs led to a significant reduction in material misstatements among clients that did not experience reductions in audit adjustments. Overall, the two effects offset each other, which explains why financial reporting quality did not improve, on average, following the introduction of MICAs.
PENGEMBANGAN PROTOTYPE FREQUENTLY ASKED QUESTION (FAQ) UNDIKSHA DENGAN PENDEKATAN USER CENTERED DESIGN
Authors: Resika Arthana I Ketut , Dantes Gede Rasben , Dewi Luh Joni Erawati , Setemen Komang , Marti Ni Wayan 
Published: February 2021

Penelitian ini bertujuan untuk mengembangkan Prototype Frequently Asked Question(FAQ) di Universitas Pendidikan Ganesha (Undiksha) dengan pendekatan User Centered Design(UCD). FAQ merupakan sistem yang memfasilitasi pengguna layanan mendapatkan jawaban terkait pertanyaan yang sering diajukan pada penyelenggaraan layanan tertentu. Pengembangan sistem ini dibutuhkan untuk memudahkan penyedia layanan dalam menjawab pertanyaan yang sering muncul. Studi kasus pengembangan FAQ ini adalah di Undiksha, mengingat Undiksha menyelenggarakan berbagai kegiatan yang melibatkan banyak pengguna seperti mahasiswa, dosen, pegawai dan masyarakat luas. Jika setiap pertanyaan dijawab langsung oleh operator kegiatan, maka akan membutuhkan waktu, biaya dan tenaga. Secara garis besar, dalam sistem FAQ Undiksha terlibat aktor pengguna layanan dan operator kegiatan. Karakteristik pengguna sistem FAQ ini beragam dengan kemampuan pengoperasian IT yang berbeda-beda, untuk itu pada penelitian ini menggunakan pendekatan UCD. Tahapan UCD meliputi Understand and specify the context of use, Specify the user and organizational requirements, Produce design solutions (prototypes) dan Evaluate designs with users against requirements. Hasil pengembangan prototype UCD adalah working prototype yang menggambarkan alur kerja sistem FAQ dari sisi pengguna layanan. Hasil pengujian usability dengan standar ISO 9241-11 pada iterasi pertama menunjukkan bahwa prototype FAQ Undiksha memiliki Efektifitas 87%, Efesiensi 98% dan Kepuasan pengguna dengan nilai 80.5. Meskipun nilai efektifitas tergolong tinggi, namun pada iterasi pertama, terdapat permasalahan usability pada task keempat, sehingga setelah dilakukan perbaikan tingkat efektifitas meningkat menjadi 93%.
IDEA OF THE SYMBOLIC GARDEN IN THE CONCEPT OF DEVELOPMENT OF AREA AROUND THE CHURCH OF URSZULA LEDÓCHOWSKA IN LUBLIN
Authors: Dudkiewicz Margot , Kawalec Katarzyna 
Published: February 2021

Each element of space is a potential sign or it can become thanks to the author’s intentions. Sign and symbol issues are used in design for the development of the area around St. Urszula Ledóchowska church in Lublin. The work defines the concept of a church garden as well as features and functions of a welldesigned object. The fieldwork consisted of carrying out a detailed dendrological inventory and assessing the condition of existing facility. Then, a conceptual design was developed, which proposed a new selection of plants with the preservation of some existing trees. The surface has been completely changed and elements of small architecture have been added. The area was divided into three zones: representative, contemplative and relaxing. The whole idea is to serve the clergy and parishioners, while being a vote of gratitude to St. Urszula Ledóchowska.
Współpraca małych i średnich przedsiębiorstw z instytucjami otoczenia biznesu w latach 2007–2013 na przykładzie województwa wielkopolskiego
Authors: Mizgajska Hanna 
Published: February 2021

Celem artykułu jest rozpoznanie zmian stopnia korzystania z usług instytucji otoczenia biznesu przez małe i średnie przedsiębiorstwa reprezentujące tradycyjne branże przemysłu w latach 2007–2013. Badania, w formie wywiadu ankietowego, przeprowadzono wśród 54 małych i średnich przedsiębiorstw w województwie wielkopolskim w latach 2011–2013. Ich wyniki porównano z podobnymi zrealizowanymi w okresie 2007–2009 w tym samym województwie. Materiał empiryczny opisano za pomocą metod statystyki opisowej. Podjęte badanie przeanalizowano na tle charakterystyki instytucji otoczenia w Polsce. W wyniku przeprowadzonej analizy stwierdzono, że w latach 2011–2013 zmieniła się intensywność i kierunki współpracy małych i średnich przedsiębiorstw z instytucjami otoczenia biznesu, została zapoczątkowana współpraca z ośrodkami innowacji i przedsiębiorczości, zwiększył się stopień korzystania przedsiębiorców z oferowanych usług – za wyjątkiem poręczeń i gwarancji kredytowych – oraz zmieniły się oczekiwania przedsiębiorców w kierunku wzrostu zainteresowania różnymi formami doradztwa biznesowego.