bluuebunny/crossref_metadata_2025_split huggingface dataset:
EVALUATION OF ESP PERFORMANCE DN1800 TO INCREASE WELL PRODUCTIVITY
Authors: Anggara Fajar 
Published: August 2021

The use of the Electrical Submersible Pump (ESP) in the oil lifting method is very popular because it is easy to install, less required installation of tools in the field and a high efficiency. To achieve the Q target, ESP parameters such as the number of stages and RPM need to be analyzed to align with the IPR (Inflow Performance Flow) curve. The use of nodal analysis is used to determine the relationship between Pwf and head pump. Iteration needs to be done to determine the range of the number of stages so that it aligns with characteristics of well. It is found that the recommended range stage is 580-600 at a well depth of 7684 ft. Moreover, it is found that with 3600 RPM and 600 stages is able to reach the Q target. The relationship between the number of stages and RPM value with Pwf is inversely proportional.
Peran Green Product Innovation Dalam Memediasi Pengaruh Corporate Social Responsibility Terhadap Kinerja Bisnis Industri Kreatif
Authors: Hadiah Fitriyah  , Bambang Tjahjadi  , Noorlailie Soewarno  
Published: August 2021

This study aims to empirically examine the role of green product innovation in mediating the influence of corporate social responsibility on the business performance of the creative industries of batik. The research approach used is quantitative research. The population is the creative industries of spread the r Sidoarjo and Bangkalan regions. The number of Small and Medium Industries of batik crafts in Sidoarjo and Bangkalan is 98 batik creative industries. The sample in this study were 79 creative industries of batik using the Slovin formula, then the determination and distribution of the sample was based on simple random sampling. The analytical method used in the data processing in this study uses SEM-PLS with the help of SmartPLS software. The results showed that: (1) corporate social responsibility (CSR) influences green product innovation (GPI) with a t value of 5.384 and a Pvalue of 0.000; (2) green product innovation (GPI) influences business performance with a t value of 5.492 and Pvalue of 0.000; (3) green product innovation(GPI) is able to mediate the influence of corporate social responsibility (CSR) business performance (BP) of creative industries with a t value of 3.771 and a Pvalue of 0.000.
Students' Perceptions of Equal Opportunities for Higher Education
Authors: Fithriana Noora , Firdausi Firman 
Published: August 2021

The research aim was measuring perception of students to equality of opportunity to get higher education at Tribhuwana Tunggadewi University. To meet the aim and collect the primary data, a questionnaire survey was held to 326 Tribhuwana Tunggadewi active students in the year of 2019 by simple random sampling. Data validation was with construct validity and Alpha Cronbach. The analyzed data was with a quantitative technique by Microsoft Excel and IBM SPSS 22. The research results measured from the prospects that most students perceived “yes” the admission pathways were diverse (M = 6); the admission phases were enough (M = 6); the information and requirements were clear (M = 6); the campus promotion got to school (M = 5); most students perceived admission opportunity to all class (M = 6); and most students perceived “no” ethnic discrimination when registering (M = 4). From the means equality, most students perceived “yes” the admission test was acceptable for all registrants (M = 6); the general test informed the score to the registrants (M = 6); the registration rules equal for all registrants (M = 6); the general test informed schedule before (M = 6); the admission considered achievements, interests, and talents (M = 6); and the applicants passed the general test accepted (M = 6). The research results had a measurement score if it was true significant that the mean of perception equals to 6 of the undergraduate students perception.
Distribution And Transport of Heavy Metals In Surface Sediments of Chengbei Sea Area In The Bohai Sea Under The Action of Multiple Factors
Authors: Lei Zhiyu , Hu Rijun , Zhang Xiaodong , Zhu Longhai , Yi Yanjun , Liu Bo , Yuan Xiaodong 
Published: August 2021

Abstract
This study analyzed the distribution characteristics of Cu, Zn, Cd, Cr, and Pb in surface sediments of Chengbei Sea area and estimated the pollution status using grain size and heavy metal data of surface sediments from June 2015. Furthermore, the main controlling factors of the distribution and transport of heavy metals are discussed from the two aspects of natural processes and human activities. The results showed that the surface sediments were not polluted by the heavy metals, except for Cd, which exhibited a small degree of pollution. Cu, Zn, and Cd were mainly attributable to natural sources, and their distribution characteristics were basically the same. Areas with high concentrations of Cu, Zn, and Cd were mainly distributed in the northeast of the study area, reflecting a clear correspondence to the zonation of the sedimentary dynamic environment. Their distribution characteristics were mainly controlled by the grain size of surface sediments. Areas with high concentrations of Cr and Pb were mainly distributed in the northwest and east-central parts of the study area, and the corresponding relationship with the zonation was not obvious. Their distribution characteristics were mainly affected by sediment transport and tidal residual current.
Developing a Needle-Knife Surgical Device
Authors: RAVAGLIA FABIO , JUNIOR ALBERTO CLIQUET 
Published: August 2021

Abstract
Introduction: Nowadays, a new era of orthopedic surgery is taking place. Procedures like video surgery, ultrasound-guided interventions, invasive pain interventions, orthopedic procedures, hydro dissection, dry needling, thermography-assisted pain management, and modern acupuncture started to be widely performed1,2. Background: In 2011 and 2012, Ravaglia & Cliquet presented papers on an Arthroscopic Needle-Knife Surgical Prototype Device (ANKSD)2 in Prague, TWC 20112, and in Dubai, OWC 20123. It was a paper presenting a prototype of a needle-knife for orthopedic procedures based on an 18G11/2 needle. Ravaglia and Cliquet wrote the paper “Comparison of two different needles used as knife on knee arthroscopic portal scalpel procedures”4, which was presented at the XXVI SICOT Triennial World Congress, in Guangzhou, China, in 2015. This research compares arthroscopic portal incisions using an 18G11/2 needle or a metal guide intravenous catheter 14Gx2. They concluded that there were no differences in complications such as infections, wound healing, hematoma, and skin healing time. After this, these researchers started a virtual development of a new needle-knife surgical device. Objective: The aim of the project is a virtual development of a needle-knife surgical device to be useful for minimally invasive ultrasound-assisted orthopedic surgical procedures, videos arthroscopic portals augmentation, and other surgical procedures. Method: Three different needle devices were compared. One is a base model 1 and the other two are experimental models (2 and 3). They are based on a metal guide for intravenous catheter 14Gx2''. The base one model 1 is the metal guide for intravenous catheter 14Gx2''; the experimental model 2 is a flat beveled edge, and experimental model 3 is a board bevel edge6,7,8,9,10,11,12,13,14,15,16. They are all graduated, parylene-coated, with a stop handle needle guard. The devices are multifunctional: Infusion, aspiration, and surgical sever.The devices were developed by 3D Design 3D STEP Standard Format, Catia V5 Format, and 2D Format Design and 3D Model. They were performed through simulation (Software Simulia Abaqus). They were biomechanically simulated with Virtual Biomechanical Strength Simulation17,18,19,20. The Strengths were assessed by Needle Strength Analysis (CAE Simulation)21.Results: For the displacement result, stiffness assessment, we have 7.48 mm for the baseline needle, 8.08mm for model 2, an increase of 8%, and for model 3 we have 7.75 mm, an increase of 3.6%. Conclusion: These devices seem suitable for echo-assisted orthopedic surgery interventions and other procedures according to virtual analysis. Further in vivo procedures shall be performed.
Digitalis Therapy in Patients With Ventricular Tachyarrhythmias
Authors: Schupp Tobias , von Zworowsky Max , Karaca Bican , Reiser Linda , Abumayyaleh Mohammad , Weidner Kathrin , Mashayekhi Kambis , Bertsch Thomas , Abba Mohammed L. , Akin Ibrahim , Behnes Michael 
Published: August 2021

Abstract
Objective: The study sought to assess the prognostic value of treatment with digitalis on long-term prognosis in patients with ventricular tachyarrhythmias and atrial fibrillation (AF) and/or heart failure (HF).Background: Data regarding outcome of digitalis therapy following ventricular tachyarrhythmias is limited.Methods: A large retrospective registry was used including consecutive patients with episodes of ventricular tachycardia (VT) or fibrillation (VF) from 2002 to 2015. Patients treated with digitalis were compared to patients without. The primary prognostic outcome was all-cause mortality at three years, secondary endpoints comprised of a composite arrhythmic endpoint (i.e., recurrences of ventricular tachyarrhythmias, sudden cardiac death) and cardiac rehospitalization. Kaplan Meier, multivariable cox regression and time trend analyses were applied for statistics.Results: A total of 831 patients were included (20% treated with digitalis and 80% without). At three years, digitalis treatment was not associated with all-cause mortality in patients with ventricular tachyarrhythmias (24% vs. 21%, log rank p=0.736; HR=1.063; 95% CI 0.746-1.515; p=0.736). However, digitalis therapy was associated with increased risk of the composite endpoint (38% vs. 23%; log rank p=0.001; HR=1.719; 95% CI 1.279-2.311; p=0.001) and cardiac rehospitalization (31% vs. 18%; log rank p=0.001; HR=1.829; 95% CI 1.318-2.538; p=0.001) at three years, which was still evident within multivariable Cox regression analyses. Finally, digitoxin was associated with worse prognosis than digoxin.Conclusion: Digitalis therapy was not associated mortality in patients with ventricular tachyarrhythmias, but with increased risk of the composite arrhythmic endpoint and cardiac rehospitalization at three years.
Fabrication of transparent spinel by the reactive spark plasma sintering of spray-dried Magnesia-Alumina nanocomposite without sintering aid
Authors: Davar F. , Heidari Nasrin , Alhaji Amir 
Published: August 2021

Abstract
In this project, magnesia-alumina composite granules were prepared using spray drying method. Next, the synthesized powder was sintered at 1400°C for 15 min under 100 MPa pressure through spark plasma sintering without using any sintering aid. The effect of two sintering temperatures of 1400 °C and 1500 °C was explored on the phase formation, density, fracture toughness, and optical transmission within visible and IR ranges. SEM results indicated that the magnesia-alumina composite granules had spherical morphology with the mean particle size of 21 micrometers. The XRD pattern showed that after the spark plasma sintering stage at 1400 °C and 1500 °C, the spinel phase of magnesium aluminate was obtained as in situ. The disc sintered at 1400 °C had greater maximum transmission compared to the samples sintered at 1500 °C (47% vs. ~70%) within the middle IR region because of lower porosity of the sample. The magnesium aluminate spinel sintered at 1400 °C had a density 99.98% of the theoretical density, hardness 18 GPa, and fracture toughness 1.6 MPam1/2.
Using a back propagation neutral network based modeling and heuristic algorithms based optimization technique in activated gas tungsten arc welding process
Authors: Moghaddam Masoud Azadi , Kolahan Farhad 
Published: August 2021

Abstract
In this study, a modeling method based on an artificial neural networks model combined with a back propagation algorithm (BPNN) and an optimization procedure based on heuristic algorithms (particle swarm optimization (PSO) and simulated annealing (SA) algorithms) have been proposed for modeling and optimization of activated gas tungsten arc welding (A-GTAW) process in order to tackle the poor penetration drawback occurs during GTAW process. in this study effect of the most important process adjusting variables including welding current (C), welding speed (S)) and percentage of activating fluxes (TiO2 and SiO2) combination (F) on the most important quality characteristics (weld bead width (WBW), depth of penetration (DOP), and consequently aspect ratio (ASR)) in welding of AISI316L austenite stainless steel parts have been investigated. Box-behnken and central composite designs (BBD and CCD) based on response surface methodology (RSM) in design of experiments (DOE) method have been employed to gather the required data for modeling and optimization purposes. Then, BPNN has been used to determine the relations between A-GTAW process input variables and output responses. To determine the proper BPNN model architecture (the proper hidden layers’ number and their corresponding neurons/nodes in each layer) PSO algorithm has been used. Next, PSO and SA algorithms have been used to optimize the proposed BPNN model in such a way that desired AR, minimum WBW, and maximum DOP achieved. Finally, confirmation experimental tests have been conducted to evaluate the proposed procedure performance. Based on the results, the proposed method is efficient in modeling and optimization (less than 7% error) of A-GTAW process.
Drought-Hardening Improve Waterlogging Tolerance of Maize at Seedling Stage
Authors: Li Caixia , Hamani Mounkaila , Sun Jingsheng , Guangshuai Wang , Huifeng Ning , Liu Zhandong , Qisheng Han 
Published: August 2021

Abstract
This study aimed to investigate the stress tolerance of maize by exploring the changes in abscisic acid (ABA) concentration, biomass accumulation, and transpiration rate of maize exposed to drought and waterlogging stress; The experiment was conducted in a controlled greenhouse by setting up a total of 17 treatments of water stress, waterlogging stress, and drought stress followed by waterlogging. A completely randomized block design was employed; Waterlogging limited the formation of maize biomass more than that by water stress. Waterlogging alone (W) inhibited more strongly the growth of the aboveground part than of the underground part, causing a de-crease in the canopy-to-root ratio. However, the canopy-to-root ratio increased under waterlogging after drought. Under drought and waterlogging stress, the ABA concentrations of maize leaves and roots changed gradually, decreasing from the leaves to the root base, then middle root, and finally root tip. Early water stress had a greater effect on leaf ABA concentration than on root ABA concentration, and leaves were the most sensitive to drought stress. Root system was more sensitive to drought stress followed by waterlogging; Moderate controlled drought at the seedling stage can improve their resistance to subsequent waterlogging stress, but the subsequent water-logging stress should not last more than 7 days.
Subtypes of m6A RNA Modification Defines Tumor Microenvironment, Immunotherapy and Pharmacogenomic Landscape in Prostate Cancer
Authors: Li Song , Hou Yifan , Hou Junqing , Li Xiaodong , Zhang Jianhua , Wang Shangren , Liu Xiaoqiang 
Published: August 2021

Abstract
Background:M6A methylation is an epigenetic modification of RNA molecules, which is potentially related to the occurrence and development of tumors. Methods:We systematically described the mRNA expression and gene changes of 20 RNA modified m6A related genes in prostate cancer(PCA), and evaluated their expression modification patterns in TCGA database samples. Two groups of clustering samples were used to find 3022 differentially expressed genes (DEGs) which were used for unsupervised clustering, and then the samples were divided into two groups of expression patterns and the significant prognosis of DEGs were screened. Then, we constructed risk scores based on survival and prognosis to quantify RNA modification related subtypes of the tumor. In addition, we also analyzed the relationship between risk_score groups and characteristics of TME, clinical pathology, drug response and the efficacy of immunotherapy. Results:We demonstrated that the prognostic risk stratification of m6A RNA modification was associated with survival, TME immune cell infiltration and immunotherapy response in patients with prostate cancer. We constructed a risk_score model based on the prognosis of m6A, which was divided into high-risk group and low-risk group. The risk_score-high group was positively correlated with Itreg cells, and the infiltration of B cells, T cells, CD4+, endothelial cells and T cells CD8+ was higher in risk_score-high group. The gene expression of each immune checkpoint was high in risk_score-high group which had higher TIDE score and MSI score than risk_score-low group. Conclusions:We conducted a comprehensive analysis and risk stratification of m6A in prostate cancer for the first time, revealed the potential functions of risk stratification in TME, immunotherapy and transcription, and determined their potential therapeutic value in targeted therapy and immunotherapy.
Differences in spatial patterns and driving factors of biomass carbon density between natural coniferous and broad-leaved forests in mountainous terrain, eastern Loess Plateau of China
Authors: Sun Lina , Wang Qixiang , Fan Xiaohui 
Published: August 2021

Abstract
Background

Mountain forests in China are an integral part of the country’s natural vegetation. Understanding the spatial variability and control mechanisms for biomass carbon density of mountain forests is necessary to make full use of the carbon sequestration potential for climate change mitigation. Based on the 9th national forest inventory data in Shanxi Province, which is mountainous terrain, eastern Loess Plateau of China, we characterized the spatial pattern of biomass carbon density for natural coniferous and broad-leaved forests using Local Getis-ord G* and proposed an integrative framework to evaluate the direct and indirect effects of stand, geographical and climatic factors on biomass carbon density for the two types of forests using structural equation modeling.
Results

There was no significant difference between the mean biomass carbon densities of the natural coniferous and broad-leaved forests. The number of spots with a spatial autocorrelation accounted for 51.6% of all plots of the natural forests. Compared with the broad-leaved forests, the hot spots at the 1% significance level for the coniferous forests were distributed in areas with higher latitude, higher elevation, lower temperature, and lower precipitation. Geographical factors affected biomass carbon density positively and indirectly, via the stand and climatic factors, with larger effects for the natural coniferous than broad-leaved forests. Latitude and elevation are the most crucial driving factors for coniferous forests, but stand age and forest coverage are for broad-leaved forests. Climatic factors had weaker effects than other factors, with negative effects of temperature for coniferous and no effects for broad-leaved forests.
Conclusions

The effects of stand, geographical and climatic factors on biomass carbon density are different between natural coniferous and broad-leaved forests, respectively. Employing the integrative framework can improve the prediction of the impact of stand, geographical and climatic factors on natural forests in mountainous areas.
The Effect of Neural Stem Cell Treatment on Astrocyte Phenotypes morphology and Galectin Expression in Following Rat Spinal Cord Injury
Authors: Kilcoyne Michelle , Dooley Dearbhaile , Patar Azim , Bergin Niall , Duane Laura , Thompson Kerry , Allsopp Timothy , Barry Frank , McMahon Siobhan 
Published: August 2021

Abstract
Traumatic spinal cord injury (SCI) results in complex neurological dysfunction. Astrocytes react in response to SCI by undergoing proliferation and migrating to the injury site, resulting in astrogliosis. Neural stem cells (NSCs) have been proposed as a promising therapeutic strategy to promote neurogenesis following transplantation post SCI. In this study the antigenic and morphological phenotype of astrocytes, and the pattern of galectin expression was examined following SCI. Female Sprague Dawley rats were contused at thoracic (T) level T9 and treated with Cyclosporin-A (CsA) and/or NSCs 1 week post-injury. CsA and NSC treatment led to increased glial fibrillary acidic protein (GFAP), brain lipid binding protein (BLBP) and vimentin expression. Quiescent and reactive astrocytes were the most abundant cell morphology observed. Astrocytes co-localised with galectin-1 (Gal-1) and galectin-3 (Gal-3). Gal-1 expression was increased in both CsA and CSA + NSC treated animals 2 weeks post-treatment. Treatment with CsA and/or NSCs offers many prospective beneficial effects. A detailed revelation of how astrocytes are heterogeneously responsive to SCI, in addition to their affinity to galectins and response to CsA and NSCs is shown in this study. The current study’s findings support the potential application of NSCs as a novel therapeutic tool in the treatment of SCI.
High-Density Ceramics Obtained By Andesite Basalt Sintering
Authors: Pavkov Vladimir , Bakić Gordana , Maksimović Vesna , Cvijović-Alagić Ivana , Đorđević Marija Prekajski , Bučevac Dušan , Matović Branko 
Published: August 2021

Abstract
Modern industrial requirements include not only the usage of constructive materials with good mechanical properties but also materials obtained through environmentally friendly and low-cost processing procedures. Basalt, as a low-cost raw material, is regarded as a good candidate for industrial constructive parts production. In the present study, andesite basalt originated from the deposit site "Donje Jarinje", Serbia, was examined as a potential raw material for high-density ceramics production. The production of high-density ceramics included dry milling, homogenization, cold isostatic pressing, and sintering in the air. To determine the optimal processing parameters the sintering was conducted at 1040, 1050, 1060, 1070, and 1080 °C, and afterward the sintering duration was varied from 30 to 240 min at the optimal sintering temperature of 1060 °C. Characterization of the starting and sintered materials included the estimation of particle size distribution, density, hardness, and fracture toughness complemented with X-ray diffraction, light optical microscopy, scanning electron microscopy, and energy dispersive spectroscopy analysis. Phase transformations did not occur during processing in the investigated temperature range from 1040 to 1080 °C. The obtained research results showed that 99.5% of relative density and the highest hardness and fracture toughness values of 6.7 GPa and 2.2 MPaÖm, respectively, were achieved for the andesite basalt sintered at 1060 °C for 60 min in the air. The results of the presented study confirmed that the sintered andesite basalt can be used as a high-density ceramic material for various industrial applications since this environmentally friendly material shows satisfactory mechanical properties.