bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimization of the Hemispherical Solar Distiller Performance Augmented by Different Basin Materials (steel, zinc, and copper) and Reflective Mirrors
Authors: Attia Mohammed El Hadi , Kabeel Abd Elnaby , Abdelgaied Mohamed , Bellila Abdelkader 
Published: November 2021

Abstract
The present comprehensive study aims to solve the problem of declining drinking water productivity from solar distillers. The hemispherical distillers are characterized by having the large condensing and receiving surface area, so the utilization of basin materials with high thermal conductivity and reflective mirrors are very effective to enhance a cumulative production of hemispherical distillation. To get the optimal basin materials with the reflective mirror that achieves the highest hemispherical distiller’s performance, three high thermal conductivity basin materials (steel, zinc, and copper) with reflective mirror were tested at the same conditions and compared to reference hemispherical unit. To realize this idea, four distillers was fabricated and tested at a same climate condition namely: Hemispherical solar Distiller with Black Silicone Walls (HSD-BSW), Hemispherical Solar Distiller with Steel Plate and Reflective Mirror (HSD-SPRM), Hemispherical Solar Distiller with Zinc Plate and Reflective Mirror (HSD-ZPRM), and Hemispherical Solar Distiller with Copper Plate and Reflective Mirror (HSD-CPRM). The experimental results presented that the utilization of copper basin materials and reflective mirror (HSD-CPRM) represents the good option to achieve the highest performance of hemispherical distiller, use the copper basin materials and reflective mirror (HSD-CPRM) gives a cumulative production reached 9500 mL/m2 day with improvement of 104.3% compared to reference hemispherical distiller (HSD-BSW). Also, use the copper basin materials and reflective mirror (HSD-CPRM) improves the daily thermal efficiency and exergy efficiency by 102.4% and 194.9%, respectively compared to HSD-BSW. The comprehensive economic analysis concluded that the use of copper basin materials and reflective mirrors (HSD-CPRM) reduced the distillate water cost per liter by 44.1% compared to HSD-BSW.
Double-sided Polishing Photonic Crystal Fiber Biosensor Based on Surface Plasmon Resonance
Authors: Zhang Zhiwen , shen tao , Liu Chi , Liu Xin , Feng Yue , Wang Shaofeng , Wei Han 
Published: November 2021

Abstract
In this paper, we propose a high-sensitivity double-sided polishing photonic crystal fiber biosensor based on surface plasmon resonance. The performance of the sensor was analyzed by finite element method, including the influence of different pore sizes and position, polishing depth, pore spacing, metal thickness, refractive index(RI), and manufacturing error (5%) on the sensing performance. We also analyze the performance of the modified sensor in early cancer detection applications. Our use of a double-sided polishing structure and coating with a gold layer not only increases the contact area between the analyte and gold layer but also provides a large enough space for the analysis channel, which is conducive to the actual manufacture and use. The sensor has a detection range of 1.35-1.39, the maximum wavelength sensitivity of 21500 nm/RIU, the average wavelength sensitivity is 9550 nm/RIU, the amplitude sensitivity of -1057.1756 RIU-1, the maximum resolution is 4.68×10-6, R2 of 0.98265, figure of merit is 250, and the maximum resolution of 4.68×10-6, which can be used in the cancer detection and other biological areas.
Traditional Chinese Medicine Reduces Hospitalization Risk of Osteoarthritis Patients: A 13- Year Population-based Cohort Study
Authors: Zhao Yanping , Wang Shuya , Wei James Cheng-Chung , Wang Yu Hsun , Zhang Zhiyi 
Published: November 2021

Abstract
Introduction：Osteoarthritis (OA) is a chronic musculoskeletal disorder of the movable joints. TCM has been widely used as complementary therapy for OA in Chinese. Traditional Chinese medicine (TCM) including Duhuojishi decoction, Shujing Huoxue decoction, Angelica Niantong decoction, Guilu Erxian glue et al are widely used in the clinical of osteoarthritis treatment. However there are very few large-scale studies about long-term effect of TCM on OA treatment. This study determined the long-term effects of TCM on reducing OA patients hospitalization risk.Material and methods: This study was a population-based retrospective cohort study. Patient data were collected from the claim-based Taiwan National Health Insurance Research Database from 2000 to 2012. We enrolled 67737 TCM treated cohort and 67737 non-TCM comparison of newly diagnosed OA patients. Propensity score matching was done on age, sex and possible confounders to ensure baseline comparability. Outcomes were medical utility, including hospitalization rate, emergency visits and direct medical expense. Logistic regression was conducted to compare the differences o between TCM and non-TCM groups. Subgroup analyses were also performed by age, gender, income and urbanization.Results: TCM group had an overall higher medical expense than non-TCM group. Although Logistic regression analysis results showed that there was no difference of emergency rate in TCM group and non-TCM group, TCM treatment reduced hospitalization rate of OA significantly.Conclusions: The usage of TCM was associated with a reduced risk of hospitalization of OA patients. TCM might play a complementary role in OA treatment.
Some Biological Aspects and Proline Metabolism Genes as Influenced by Polyethylene Glycol and Salicylic Aacid in Two Wheat Cultivars
Authors: Loutfy Naglaa , Hassanein Ahmed , Inouhe Masahiro , Salem Jehan 
Published: November 2021

Abstract
The aim of this work was to study the response of two wheat cultivars with different drought tolerance to PEG (-0.4 Mpa) and SA (0.5 mM). Data of seed germination and seedling growth indicated that Misr-2 cultivar was more drought tolerant than Gemmeiza-12. Under non- stress conditions, Misr-2 had higher values of pigments, soluble sugars (Glu, Fru and Suc) and activities of antioxidant enzymes (CAT, APOX, GPOX and SOD) but lower values of proline than those of Gemmeiza-12. The cultivar with a higher proline content (Gemmeiza-12) compared to the other cultivar had a higher expression of proline synthesizing gene (P5CS) but lower expression of proline degrading genes (PDH and P5CDH). Under drought conditions, the drought-sensitive (Gemmeiza-12) needed more osmoregulators and antioxidants than drought-tolerant cultivar (Misr-2) to minimize the negative effects of water and associated oxidative stresses. Therefore, soluble sugars, proline content and anti-oxidation enzymes were higher in Gemmeiza-12 than Misr-2. Also, under drought stress, up-regulation of P5CS and down-regulation of PDH and P5CDH in Gemmeiza-12 were higher than Misr-2. While treatment of the stressed plants with SA up-regulated P5CS gene in both cultivars, down-regulation of PDH and P5CDH in Gemmeiza-12 was clearer than Misr-2.
C-Reactive Protein Promotes Tumor Progression in Hepatocellular Carcinom by Interacting with Ephrin Type-B Receptor 3
Authors: She Sha , Yang Min , Li Shi Ying , Hu Huai Dong , Yang YiXuan , Ren Hong 
Published: November 2021

Abstract
Background

C-reactive protein (CRP), an acute phase protein, has been increasingly implicated in various tumors, and the role of CRP is positively correlated with invasion and metastasis in hepatocellular carcinoma cells. However, the mechanism of CRP affecting HCC progression remains poorly investigated. The present study investigated the role of CRP in HCC and the underlying mechanisms.
Methods

In the current study, CRP overexpression and suppression expression experiments were used to evaluate the effect of CRP on malignant biological behavior of liver cancer cells in vitro. Then iTRAQ-mass spectrometry analysis was used to identify CRP co-immunoprecipitation complexes. Detecting the interaction between CRP and Eph receptor B3 (EphB3) by co-precipitation. Moreover, immunofluorescence colocalization and co-precipitation, and Western Blot, in vivo model were applied to study the molecular mechanism of CRP affecting the development of Hepatocellular Carcinoma.
Results

We first found that CRP was significantly upregulated in HCC tissues and HCC cells, the expression level correlated with the metastatic ability of HCC cells. Knockdown of CRP significantly suppresses migration and invasion capacity in HCC cells. Through a proteomic analysis of CRP co-immunoprecipitation complexes, the EphB3 was identified as a new CRP interactor. Then we found that the expression and functions of EphB3 were consistent with CRP in HCC. In addition, co-immunoprecipitation and immunofluorescence assays suggested that EphB3 was able to interact with MAPK/ERK to activate MAPK/ERK signaling pathways. Furthermore, we showed that CRP can induce the phosphorylation of MAPK/ERK by binding EphB3. CRP also significantly stimulated MMP-9 expression, mainly by activating HIF-1α via the MAPK/ERK pathways.
Conclusions

Our findings showed that CRP increased HCC cells migration and invasion by binding EphB3 to activate MAPK/ERK signaling pathways. It suggested that CRP may become a prognostic factor and a potential therapeutic target for liver cancer.
Noteworthy Bio Resource Utilization and Eco-Friendly Bioconversion Approaches of Versatile Invasive Aquatic Weed Water Hyacinth (Eichhornia Crassipes) Biomass - A Green Strategy for Aquatic Environmental Safety and Management of Aquatic Weeds.
Authors: Selvaraj Karthick Raja Namasivayam , Vigneshwaraprakash Lakshmanan , Arvindbharani Rajansowri , Vivek JanarathanamManivannan 
Published: November 2021

Abstract
Eichhornia crassipes (Water hyacinth) is considered as a hazardous weed in numerous places of the world. Despite of its harmful effects, the weed offers potential substrate for production of monetarily industrial important and value added products. In the present study, an eco-friendly bioconversion or biotransformation of processed water hyacinth biomass (WHB) into high efficiency fuel, adsorbent for brewery industry waste water treatment coupled methylene blue dye, biofertilizer and nutrient media for viable inoculam production of fungal biopesticide Nomuraea rileyi was carried out adopting green science in situ principles. Bioconversion of the WHB was initiated by alkali treatment which brought about notable differences in physical texture and chemical composition. Pre-treated WHB was enzymatically hydrolysed into soluble simple sugars followed by fermentation of the sugar into ethanol with 65.2 % total yield with 77.3 g/l final concentration. Batch studies reveals that WHB brought about effective reduction of various physicio chemical properties and notable adsorption efficacy. Plant growth promoting effect was studied using green gram (Vigna mungo). Green gram grew on soil under pot culture technique inoculated with WHB uncovers imperative plant growth promotion effect. Culture medium prepared from reconstituted WHB supported viable inoculum production of potential fungal biopesticide Beauveria bassiana. Fungal inoculum derived from the WHB based culture medium was effective against larval instars of castor semi-looper Achaea janata in terms of high mortality.The present examination uncovers the conceivable viable bioconversion of water hyacinth biomass (WHB) into different worth included vitality, ecological as gives a green procedure to cleaner production and the executives of aquatic invasive weeds.
Relationship Between the Visual Evoked Potential and Structure in the Primary Visual Cortex in Healthy Individuals and in Patients with Severe Mental Disorders
Authors: Slapø Nora Berz , Jørgensen Kjetil , Elvsåshagen Torbjørn , Nerland Stener , Roelfs Daniel , Valstad Mathias , Timpe Clara , Richard Genevieve , Beck Dani , Sæther Linn Sofie , Werner Maren , Lagerberg Trine , Andreassen Ole , Melle Ingrid , Agartz Ingrid , Westlye Lars T. , Moberget Torgeir , Jönsson Erik G. 
Published: November 2021

Abstract
Schizophrenia (SCZ) spectrum and bipolar disorder (BD) are severe mental disorders with unknown pathophysiology. Altered visual evoked potential (VEP), an electroencephalogram signal reflecting function in the primary visual cortex (V1), abnormal visual processing and visual hallucinations reported in these patients, all point towards V1 dysfunction. While the mechanisms contributing to V1 dysfunction remain unknown, structural alterations are possible candidates. Lack of insight into neural substrates of structure and functional in V1 has limited our ability to determine implications of altered V1 function. While combining VEP and magnetic resonance imaging has increased our understanding of the structure-function relationship in V1 in healthy individuals, no previous study has examined the same structure-function relationship in patients with SCZ spectrum and BD. Here, we aimed to confirm previous findings of a selective positive correlation between the amplitude of the P100 component of the VEP and V1 surface area (SA) in 307 healthy individuals and to examine whether this relationship was altered in patients with SCZ spectrum (n=30) and BD (n=45). The correlation between the P100 amplitude and the total, (r=0.16, p=0.006), right (r=0.14, p=0.013) and left V1 surface area (r=0.13, p=0.02) was significant in healthy individuals, but not in patients. The current results support previous findings of a selective relationship between P100 amplitude and V1 surface area in healthy individuals and suggests that other factors than V1 surface area or thickness explain V1 dysfunction reported in these patients.
Extracto de Acacia farnesiana para el control de larva de Aedes aegypti
Authors: Granados Montelongo Juan Antonio , Núñez Colima Juan Antonio , Trujillo Zacarías Issanelly , Cano del Toro Jesús , Chan-Chablefirma Rahuel J. , Hidalgo de León Aimir 
Published: November 2021

Introducción: Aedes aegypti es el principal vector de dengue, chikunguña, fiebre amarilla y zika en el mundo; el control químico es el más utilizado para su prevención, atacando la reproducción del mosquito vector, principalmente mediante la aplicación de insecticidas sintéticos en sus lugares de cría. Sin embargo, el uso de insecticidas sintéticos ha generado resistencia en los mosquitos y diversos problemas ecológicos. Los extractos naturales de plantas con función insecticida son utilizados como alternativa para el control de vectores. El objetivo del presente estudio fue evaluar la actividad larvicida del extracto de vaina de Acacia farnesiana contra larvas de cuarto estadio de Ae. aegypti.
Método: el estudio fue desarrollado en el Laboratorio del Instituto Tecnológico Superior de San Pedro, Coahuila, y en el ejido Mayran, San Pedro, Coahuila, México. Para la elaboración del extracto se utilizó la metodología propuesta por INIFAP-CENID-RASPA 1997. Los productos extractados se utilizaron en los bioensayos con larvas de cuarto estadio de Ae. aegypti durante 168 horas. Se transfirieron grupos de 20 larvas en vasos plásticos con 50 mL de agua, luego se aplicó 1 mL de cada uno de los tratamientos de fruto de Acacia farnesiana con concentraciones finales de 15 % (T1), 25 % (T2), 35 % (T3) y 70 % (T4). Para el control químico se utilizó Abate® 1SG (Temefos) al 25 %. Al testigo no se aplicó ningún tratamiento. Para comparar la mortalidad se realizó un análisis de varianza de un factor para cada uno de los estudios (laboratorio y campo) y un análisis de medidas repetidas en el tiempo para la fase de campo. Se desarrolló una prueba de comparación de medias de Tukey. Los análisis se realizaron usando el programa computacional estadístico IBM.SPSS 18, con un nivel de significancia de P ≤ 0.05.
Resultados: en el laboratorio, el extracto de A. farnesiana al 35 % de concentración mostró mayor toxicidad contra las larvas de Ae. aegypti obteniendo una mortalidad media de 15.66 (78.3 %), transcurridas las 72 horas después de la aplicación del tratamiento (P ≤ 0.05). De igual forma, en condiciones de campo, el tratamiento al 35 % resultó ser el más efectivo, alcanzando una media de 19.04 (95.2 %) larvas muertas.
Discusión o Conclusión: el extracto de A. farnesiana mostró actividad insecticida contra larvas de Ae. aegypti, siendo más efectivo a una concentración de 35 % en condiciones de laboratorio y campo. El efecto larvicida del extracto de A. farnesiana puede ser utilizado como una alternativa factible y sustentable para el control Ae. aegypti en zonas rurales. Sin embargo, es necesario realizar más estudios para identificar los ingredientes activos y el mecanismo de acción presente en las vainas de A. farnesiana para el control de vectores.
Modeling of the dynamics of tornado structures in a pipe with turbulators of square, semicircular and triangular profiles
Authors: Lobanov I. E. 
Published: November 2021

Objectives. To carry out mathematical simulations of changes in time of tornado compositions in channels with projections of semicircular, triangular, square profiles for average Reynolds criteria based on multiblock computing technology with the solution of finite- volume factorized methods of the Reynolds equation and energy equations.Method. The calculations were carried out on the basis of theoretical approaches based on the solution of Reynolds equations by finite-volume factorized methods, which were closed using the simulation of Menter stresses, and the energy of a structured grid.Result. The calculations of time-dependent flow and heat transfer parameters carried out in the article showed that the excess dissipation of turbulence generation for projections of sharp profiles - square profile, triangular profile - and rounded profiles - semicircular profile, segment profile - is provided with radically different hydraulic losses: channels with protrusions of rounded profiles, for example, semicircular, have much lower hydraulic resistance coefficients than channels with protrusions with sharp profiles, for example, triangular or square, rectangular.Conclusion. In the article, mathematical simulations of time-dependent tornado compositions were performed in channels with transversal profiles in the form of a square, triangle and semicircle, which is as informative as possible in terms of studying turbulent flows and heat transfer arising under average Reynolds criteria based on computer multiblock technology when using solutions of finite-volume factorized methods (FCOM-am) Reynolds equations and energy equations. The following protrusions were considered in the article: square transversal profiles, in which tornadoes are most pronounced, and side tornadoes affect the flow in the maximum way; triangular transversal profiles, where tornadoes are not so strong, and side tornadoes affect the main flow weaker than with square protrusions; semicircular transversal profiles, in which the incoming main tornado moves along the stream with the generation of limited side tornadoes. The calculated information obtained in the article correlates to a high degree with the available experimental data, which indicates the verification of the mathematical modeling involved in the article.
Algorithm of fire detection for multi-sensor system
Authors: Bagutdinov R. A. , Stepanov M. F. 
Published: November 2021

Objective. The paper proposes a fire detection algorithm for a multisensor system. Due to the difficult conditions in the field, for the first time, watch rescue operations are difficult and often endanger the lives of rescuers. The main scientific goal is for the system to work autonomously on certain segments of the monitoring process, while the three agents, to varying degrees, must interact with each other based on communication and decision-making algorithms.Method. There are many algorithms for image processing, but algorithms that use several sources of information are not sufficiently developed and described. The focus is on fire detection algorithms. The algorithm was developed using NI Vision Assistant, a software tool for rapid prototyping and testing of imaging applications.Result. In addition to the software implementation in C, which NI Vision Assistant generates by default, the paper presents a Python implementation of the algorithm.Conclusion. The results of the work can be used to develop multisensor systems for monitoring hard-to-reach areas.
Electronic Health Record Implementations and Insufficient Training Endanger Nurses’ Well-being: Cross-sectional Survey Study
Authors: Heponiemi Tarja , Gluschkoff Kia , Vehko Tuulikki , Kaihlanen Anu-Marja , Saranto Kaija , Nissinen Sari , Nadav Janna , Kujala Sari 
Published: November 2021

BackgroundHigh expectations have been set for the implementations of health information systems (HIS) in health care. However, nurses have been dissatisfied after implementations of HIS. In particular, poorly functioning electronic health records (EHRs) have been found to induce stress and cognitive workload. Moreover, the need to learn new systems may require considerable effort from nurses. Thus, EHR implementations may have an effect on the well-being of nurses.ObjectiveThis study aimed to examine the associations of EHR-to-EHR implementations and the sufficiency of related training with perceived stress related to information systems (SRIS), time pressure, and cognitive failures among registered nurses. Moreover, we examined the moderating effect of the employment sector (hospital, primary care, social services, and others) on these associations.MethodsThis study was a cross-sectional survey study of 3610 registered Finnish nurses in 2020. EHR implementation was measured by assessing whether the work unit of each respondent had implemented or will implement a new EHR (1) within the last 6 months, (2) within the last 12 months, (3) in the next 12 months, and (4) at no point within the last 12 months or in the forthcoming 12 months. The associations were examined using analyses of covariance adjusted for age, gender, and employment sector.ResultsThe highest levels of SRIS (adjusted mean 4.07, SE 0.05) and time pressure (adjusted mean 4.55, SE 0.06) were observed among those who had experienced an EHR implementation within the last 6 months. The lowest levels of SRIS (adjusted mean 3.26, SE 0.04), time pressure (adjusted mean 4.41, SE 0.05), and cognitive failures (adjusted mean 1.84, SE 0.02) were observed among those who did not experience any completed or forthcoming implementations within 12 months. Nurses who perceived that they had received sufficient implementation-related training experienced less SRIS (F1=153.40, P<.001), time pressure (F1=80.95, P<.001), and cognitive failures (F1=34.96, P<.001) than those who had received insufficient training. Recent implementations and insufficient training were especially strongly associated with high levels of SRIS in hospitals.ConclusionsEHR implementations and insufficient training related to these implementations may endanger the well-being of nurses and even lead to errors. Thus, it is extremely important for organizations to offer comprehensive training before, during, and after implementations. Moreover, easy-to-use systems that allow transition periods, a re-engineering approach, and user involvement may be beneficial to nurses in the implementation process. Training and other improvements would be especially important in hospitals.