bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perceptions of factors influencing engagement with health and wellbeing apps: a qualitative study using the COM-B model and Theoretical Domains Framework.
Authors: Szinay Dorothy , Perski Olga , Jones Andy , Chadborn Tim , Brown Jamie , Naughton Felix 
Published: January 2021

OBJECTIVES.

User engagement with health and wellbeing apps is typically poor. Understanding factors that influence engagement can inform the design of more engaging apps. This study explored users’ experiences of and reasons for engaging and not engaging with health and wellbeing apps.

METHODS.

UK-based adults (N=17) interested in using a health or wellbeing app took part in a semi-structured interview to explore experiences of engaging with these apps. Data were analysed with the framework approach, informed by the Capability, Opportunity, Motivation – Behaviour (COM-B) model and the Theoretical Domains Framework, two widely used frameworks that incorporate a comprehensive set of behavioural influences.

RESULTS.

Factors to influence _capability_ included accessible information (e.g. user guidance, statistical and health information), reduced cognitive load, well-designed reminders, self-monitoring features, features that help to establish a routine, features that offer safety netting and stepping-stone app characteristics. Tailoring, peer support and embedded professional support were identified as important factors that enhance users’ _opportunities_ for engagement. Feedback, rewards, encouragement, goal setting, action planning, self-confidence and commitment were judged to be _motivation_ factors that affect engagement.

CONCLUSION.

Multiple factors were identified across all components of the COM-B model that may be valuable for the development of more engaging health and wellbeing apps. Engagement appears to be influenced primarily by features that provide user guidance, promote minimal cognitive load and support self-monitoring (_capability_), provide embedded social support (_opportunity_), and goal setting with action planning (_motivation_).
Pengembangan Bahan Ajar Bahasa Arab On-Line Berbasis Website Wakelet pada Program Intensif Pusat Pengembangan Bahasa UIN Maulana Malik Ibrahim Malang
Authors: Husein Sahya , Hamid Muhamad Abdul , Umar M. Sayid 
Published: January 2021

Hasil penelitian ini adalah: 1) Produk akhir dari penelitian dan pengembangan ini adalah sistem bahan ajar bahasa Arab online berbasis website Wakelet yang didesain dengan menggunakan ADDIE (Analysis-Design-Development-Implementation-Evaluation). Aplikasi bahan ajar online yang dikembangkan ini dirancang untuk perkuliahan selama enam belas kali pertemuan (satu semester untuk bobot dua SKS) di Pusat Pengembangan Bahasa UIN Maulana Malik Ibrahim Malang dengan link https://wakelet.com/i/invite?isSpace=true&code=TbJlHI untuk Wihdah lima dan https://wakelet.com/i/invite?isSpace=true&code=QCvOWs untuk Wihdah enam. 2) Hasil ujicoba terhadap komponen-komponen bahan ajar bahasa Arab online berbasis Wakelet ini menunjukkan bahwa: ahli rancangan pembelajaran memberikan penilaian bahwa ini sangat baik dan memudahkan mahasiswa untuk belajar bahasa Arab online dari tempat mereka masing-masing. Hal ini dikarenakan aplikasi ini mudah dioperasikan di smartphone dan laptop, tidak membutuhkan banyak kuota internet, dan tampilannya juga menarik.
Las características de la empresa exportadora española (2018)
Authors: Instrumentos de Política Comercial S.G. de Estudios y Evaluación de 
Published: January 2021

El objetivo de este artículo es analizar los rasgos de la empresa exportadora española de mercancías a partir de las estadísticas de comercio exterior por características de la empresa que publican Aduanas y Eurostat. Con ello se pretende conocer mejor la estructura de la base exportadora española y disponer de una referencia válida para el diseño e instrumentación, tanto de la política de apoyo a la internacionalización de las empresas, como de las propias estratégicas comerciales de las empresas. Este análisis descriptivo, principalmente de corte transversal para el año 2018, examina la relevancia de las distintas variables que caracterizan a la empresa, como su tamaño, actividad principal, control de la propiedad, la regularidad exportadora o su naturaleza de empresas importadoras.
Los últimos datos disponibles en el momento de realizar este articulo corresponden al año 2018, por lo que no se ven afectados ni por el Brexit, que tuvo lugar el 31 de enero de 2020, ni por la pandemia de la COVID-19, efectos que sólo podrán ser analizados cuando se publiquen los datos correspondientes a 2020.
Kana Wa Akhwatuha dalam Surah Al-Maidah (Studi Analisis Sintaksis)
Authors: Majid Zul Arsil , Lawang Hasanna , Hamid Nurfarida 
Published: January 2021

Penelitian ini adalah penelitian kualitatif dengan desain kajian pustaka. Data yang dikaji berupa kana wa akhawatuha dalam Surah Al-Maidah. Instrumen penelitian yang digunakan pada penelitian ini adalah berupa kartu data. Teknik pengumpulan data menggunakan metode dokumentasi. Hasil penelitian pada kana wa akhawatuha dalam Surah Al-Maidah (1) terdapat 43 kana wa akhawatuha yang terdiri atas 23 kana berupa fi’il madhi (verba perfektum), 6 kana berupa fi’il mudhari’ (verba imperfektum), dan 1 kana berupa fi’il amr (verba imperatif), 4 ashbaha berupa fi’il madhi (verba perfektum) dan 1 ashbaha berupa fi’il mudhari’ (verba imperfektum), 3 laisa berupa fi’il madhi (verba perfektum), 1 ma zala berupa fi’il mudhari’ (verba imperfektum), dan 3 ma dama berupa fi’il madhi (verba perfektum). (2) Ragam kana wa akhawatuha dari segi pengamalannya terdapat 39 fi’il yang mengamalkan tanpa syarat, 1 fi’il yang didahului la nafi, dan 1 fi’il yang beramal dengan syarat didahului ma mashdariyyah dhorfiyyah. Sedangkan dilihat berdasarkan ketashrifannya terdapat 36 fi’il kamilut tashrif, 1 fi’il naqishut tashrif dan 6 fi’il yang tidak dapat ketashrif dan dilihat berdasarkan butuh atau tidaknya pada khabar terdiri atas 42 fi’il naqish dan 1 fi’il tam. (3) Jenis isim kana wa akhawatuha dilihat dari segi makna, terdapat 3 isim zhahir dan 40 isim dhamir, jika dilihat berdasarkan bilangan, terdapat 16 isim mufrad, 1 isim tatsniah dan 26 isim jama’ dan jika dilihat berdasarkan gender, terdapat 40 isim mudzakkar, 2 isim muannats dan 1 isim musytarak. Jenis khabar kana wa akhawatuha terdapat 17 khabar mufrad, 15 jumlah fi’liyyah, 10 jar majrur dan 1 yang tidak mempunyai khabar karena termasuk kana tam.
An Experimental Investigation into the Effect of Asphalt Binder Modified with SBR Polymer on the Moisture Susceptibility of Asphalt Mixtures
Authors: Hamedi Gholam Hossein , Sahraei Ali , Hadizadeh Pirbasti Mohammad 
Published: January 2021

There are several experimental methods for improving the moisture strength of asphalt mixtures. Utilization of anti-stripping materials is the most prevalent method. In the present paper, the influence of polymer materials on asphalt binder was investigated using repetitive loading test in wet and dry conditions along with thermodynamic parameters based on the Surface Free Energy components of asphalt binder and aggregates. The results obtained from the present study indicated that using Styrene Butadiene Rubber polymer has improved the asphalt mixtures strength against the moisture damage, especially in the specimens made of granite aggregates. Also, Styrene Butadiene Rubber polymer increased the cohesion free energy and reduced the energy released by the system during the stripping event, which represented a decrease in the tendency for stripping. The stripping percentage index, which is obtained by a combination of the results of the repetitive loading test in wet and dry conditions along with the results of thermodynamic parameters, represented that the specimens made of controlled asphalt binder in the loading cycles under wet conditions had a higher stripping rate. It was also concluded that the modulus loss rate in the control asphalt mixtures was faster than the modified specimens.
АСПЕКТНИЙ АНАЛІЗ ГЕНЕЗИ КАТЕГОРІЇ «ГАРМОНІЯ»
Authors: Борзик О. Б. 
Published: January 2021

Стаття присвячена аспектному аналізу ґенези категорії «гармонія». Установлено, що сучасне суспільство потребує професійних дій щодо окультурення, утвердження морально-ціннісних орієнтирів, сприяння самоусвідомленню того, що людина є гармонійною часточкою Всесвіту та відновлення гармонії у системі людина-людина-природа-суспільство. З’ясовано, що відповідно до специфіки певного напряму науки різні аспекти феномену «гармонія» безпосередньо чи опосередковано розкриваються філософією, психологією, етикою, естетикою та педагогікою. Аналіз наукової літератури засвідчив, що гармонія є філософською категорією, розуміння якої в кожному історичному часовому проміжку пов’язане з проблемами космології, гносеології, етики, базисом яких є естетичні ідеали та уявлення про особистість, суспільство та світобудову. Установлено, що вперше лексема «гармонія» зустрічається у міфології давніх греків. Доведено, що Античність сформувала раціоналістичну гармонію як пайдею, що відображає духовні, моральні, етичні й естетичні імплікації. Наголошено, що прихід епохи Нового часу надає естетичне пояснення явищу гармонії як прекрасного: результат зміни світогляду особистості, злиття внутрішнього світу в єдине гармонійне ціле шляхом вольової діяльності. З’ясовано, що у Новітньому часі розуміння гармонії набуває більш диференційного та структурованого вигляду, де простежуються не лише філософські, але й психологічні аспекти. Установлено, що наприкінці ХХ століття уявлення про гармонію піддається іронічному, деструктивному поштовху редукції, змінити які покликане ХІХ століття шляхом відновлення втрачених духовних, моральних істин. Доведено, що сучасні науковці розкривають поняття «гармонія» крізь призму благополуччя, краси та духовності.
Uso do plasma convalescente em pacientes graves pelo COVID-19: Revisão qualitativa de série de casos
Authors: Rocha Gabriel Couto , Camelier Aquiles Assunção , Santana Lorhany dos Santos , Camelier Fernanda Warken Rosa , Maciel Roberto Rodrigues Bandeira Tosta 
Published: January 2021

O objetivo desta pesquisa foi encontrar e avaliar a eficácia e a segurança do uso de plasma de pacientes recuperados para o tratamento de pacientes graves com COVID-19 (SARS-CoV-2), atraves de série de casos. A bsuca ocorreu nas bases de dados científicas como, Lilacs, MEDLINE, Google Academics, Scielo e Science Direct. Após a aplicação dos filtros para busca avançada, e do rastreamento por título, foi feito a leitura dos resumos pré-inclusos, depois avaliados na integra para extração de dados e síntese das informações e resultados. Ao final, três estudos observacionais do tipo série de casos foram incluídos. Os pacientes em estudo, estava usando madicamentos de forma paralela ao procedimento (ex.: antibioticios, antiviais e esteroides). Os pacientes, de forma geral, tiveram melhoras na maioria dos sintomas clinicos, como também, na diminuição dos títulos virais do SARS-CoV-2, nenhum evento adverso foi passivo de alerta. Conclue-se que as evidências encontradas neste trabalho são heterogênas e com bastante limitações, acerca de dose tranfundida, tempo de tratamento e critérios para elegir os pacientes, assim, devido as restrinções apresentadas, se faz necessiário realizações de ensaios clínicos com desenhos de estudo delineados, para certificar a segurança e efetividade do tratamento.
Uso e ocupação do solo do município de novo progresso no Estado do Pará-Brasil
Authors: Rosário Raimara Reis do , Barbosa Mateus Trindade , Carneiro Francimary da Silva , Costa Merilene do Socorro Silva 
Published: January 2021

O objetivo foi analisar o processo de uso e ocupação do solo do município de Novo Progresso no Estado do Pará, interligando-o com as atividades de maior importância econômica desenvolvidas nesta região. Utilizou-se o shapefile de limite do município de Novo Progresso na plataforma online Google Earth Engine (GEE), que disponibilizou um mosaico de imagens orbitais, do satélite Landsat-8/OLI-TIRS, referentes ao ano de 2019. O processo de classificação foi feito a partir do Code Editor do GEE, utilizando um Índice espectral de vegetação para auxiliar a classificação (Normalized Difference Vegetation Index – NDVI). Foi utilizado o Software QGis 3.10.6 para elaborar os mapas de localização do município e o de classificação de uso e cobertura do solo. Os dados foram tabulados em planilhas para determinar as taxas de crescimento do período analisado. Para realizar a avaliação da confiabilidade da classificação foi utilizado o método de Exatidão Global e o Índice Kappa. Foi possível identificar que no ano de 2019, houve a incidência de 3.064.396,65 ha (80,3%) de floresta densa, uma área de 496.104,07 ha (13,0%) com solo exposto, 248.052,03 ha (6,5%) de floresta secundária, e apenas 7.632,37 ha (0,2%) com predominância de hidrografia, totalizando uma área de 3.816.185,13 ha. As áreas que encontram-se com o solo exposto não estão diretamente relacionadas com o crescimento populacional, mas sim a forma como é estabelecido o uso do solo, com base nas principais atividades desenvolvidas na região considerando que a lógica produtiva ocorre de forma desordenada, não respeitando os critérios de desenvolvimento sustentável.
POLA PERESEPAN ANTIBIOTIK PROFILAKSIS PRE BEDAH SECTIO CAESAREA DI RUMAH SAKIT
Authors: Saleh Chusun , Kurniasari Maya 
Published: January 2021

Caesarean section is a surgery to give birth to a child through surgery on the abdominal wall and uterus. Prophylactic antibiotics are preventive antibiotics in Sectio Caesarean surgery. This study aims to determine the pattern of prescribing prophylactic antibiotics in preoperative caesarean section patients which are grouped into 4 specific objectives, namely: patient characteristics such as (age, parity status, payment status), antibiotic class, type of antibiotic, and to determine surgical wound indication ILO, This study used a descriptive method by retrospectively taking data by looking at the prescription (e-prescription), patient medical record data and SOAP (Subjective, Objective, Assessment, Planning). The results showed that out of 300 patients who were parturient, 52 patients (17.3%) had normal delivery and 248 patients with caesarean delivery (82.7%). Most of the ages were between 20-30 years as many as 123 patients (49.6%) and aged > 30-40 years as many as 120 patients (48.38%). As for the status of the most payments in cash, namely 176 patients (71%). The most frequently used antibiotic class is the Cephalosporin group, namely 246 patients (99.6%), the most commonly used type of antibiotic is Ceftriaxon, which is 175 patients (70.6%). The study on Surgical Wound Infection was found in only 1 patient (0,4%) with the antibiotic Ceftriaxon.
Biomechanical Study of a Tricompartmental Unloader Brace for Patellofemoral or Multicompartment Knee Osteoarthritis
Authors: McGibbon Chris A. , Brandon Scott , Bishop Emily L. , Cowper-Smith Chris , Biden Edmund N. 
Published: January 2021

Objective: Off-loader knee braces have traditionally focused on redistributing loads away from either the medial or lateral tibiofemoral (TF) compartments. In this article, we study the potential of a novel “tricompartment unloader” (TCU) knee brace intended to simultaneously unload both the patellofemoral (PF) and TF joints during knee flexion. Three different models of the TCU brace are evaluated for their potential to unload the knee joint.Methods: A sagittal plane model of the knee was used to compute PF and TF contact forces, patellar and quadriceps tendon forces, and forces in the anterior and posterior cruciate ligaments during a deep knee bend (DKB) test using motion analysis data from eight participants. Forces were computed for the observed (no brace) and simulated braced conditions. A sensitivity and validity analysis was conducted to determine the valid output range for the model, and Statistical Parameter Mapping was used to quantify the effectual region of the different TCU brace models.Results: PF and TF joint force calculations were valid between ~0 and 100 degrees of flexion. All three simulated brace models significantly (p &lt; 0.001) reduced predicted knee joint loads (by 30–50%) across all structures, at knee flexion angles &gt;~30 degrees during DKB.Conclusions: The TCU brace is predicted to reduce PF and TF knee joint contact loads during weight-bearing activity requiring knee flexion angles between 30 and 100 degrees; this effect may be clinically beneficial for pain reduction or rehabilitation from common knee injuries or joint disorders. Future work is needed to assess the range of possible clinical and prophylactic benefits of the TCU brace.
Measures of Interjoint Coordination Post-stroke Across Different Upper Limb Movement Tasks
Authors: Schwarz Anne , Veerbeek Janne M. , Held Jeremia P. O. , Buurke Jaap H. , Luft Andreas R. 
Published: January 2021

Background:Deficits in interjoint coordination, such as the inability to move out of synergy, are frequent symptoms in stroke subjects with upper limb impairments that hinder them from regaining normal motor function. Kinematic measurements allow a fine-grained assessment of movement pathologies, thereby complementing clinical scales, like the Fugl–Meyer Motor Assessment of the Upper Extremity (FMMA-UE). The study goal was to investigate the effects of the performed task, the tested arm, the dominant affected hand, upper limb function, and age on spatiotemporal parameters of the elbow, shoulder, and trunk. The construct validity of the metrics was examined by relating them with each other, the FMMA-UE, and its arm section.Methods:This is a cross-sectional observational study including chronic stroke patients with mild to moderate upper limb motor impairment. Kinematic measurements were taken using a wearable sensor suit while performing four movements with both upper limbs: (1) isolated shoulder flexion, (2) pointing, (3) reach-to-grasp a glass, and (4) key insertion. The kinematic parameters included the joint ranges of shoulder abduction/adduction, shoulder flexion/extension, and elbow flexion/extension; trunk displacement; shoulder–elbow correlation coefficient; median slope; and curve efficiency. The effects of the task and tested arm on the metrics were investigated using a mixed-model analysis. The validity of metrics compared to clinically measured interjoint coordination (FMMA-UE) was done by correlation analysis.Results:Twenty-six subjects were included in the analysis. The movement task and tested arm showed significant effects (p&lt; 0.05) on all kinematic parameters. Hand dominance resulted in significant effects on shoulder flexion/extension and curve efficiency. The level of upper limb function showed influences on curve efficiency and the factor age on median slope. Relations with the FMMA-UE revealed the strongest and significant correlation for curve efficiency (r= 0.75), followed by shoulder flexion/extension (r= 0.68), elbow flexion/extension (r= 0.53), and shoulder abduction/adduction (r= 0.49). Curve efficiency additionally correlated significantly with the arm subsection, focusing on synergistic control (r= 0.59).Conclusion:The kinematic parameters of the upper limb after stroke were influenced largely by the task. These results underpin the necessity to assess different relevant functional movements close to real-world conditions rather than relying solely on clinical measures.Study Registration:clinicaltrials.gov, identifier NCT03135093 and BASEC-ID 2016-02075.
ROS-Sensitive Nanoparticles Co-delivering Dexamethasone and CDMP-1 for the Treatment of Osteoarthritis Through Chondrogenic Differentiation Induction and Inflammation Inhibition
Authors: Wu Xiaodong , Li Pengpeng , Cheng Jian , Xu Qiang , Lu Beiji , Han Conghui , Huo Weiling 
Published: January 2021

Objective: Osteoarthritis (OA) is a common subtype of arthritis. To date, treatment of OA focuses primarily on alleviating pain and improving joint function. The lack of a vascular system within synovial joints and the rapid removal of agents due to synovial exchange hinder continuous delivery of OA drugs. However, these obstacles are being addressed by promising nanoscale drugs.Methods: We synthesize and assemble a hydrogen peroxide [H2O2, belongs to the category of active oxygen species (ROS)]-sensitive nanomicelle, which is loaded with the anti-inflammation drug dexamethasone and chondrogenic differentiation factor cartilage-derivedmor-phogeneticprotein-1. The micelle can induce bone marrow mesenchymal stem cells to repair cartilage while inhibiting joint inflammation.Results: The prepared nanoparticles were of uniform size and displayed an obvious core-shell structure. Under H2O2 stimulation, the shell layer could be removed gradually. The drug-loaded micelle effectively inhibited proliferation of activated macrophages, induced macrophage apoptosis with an anti-inflammatory effect, and caused the BMSCs to differentiate into chondrocytes.Conclusion: This work provides an experimental and theoretical basis for further development of a drug-loaded micelle in the healing of osteoarthritis.
Preoperative Folate Receptor-Positive Circulating Tumor Cell Level Is a Prognostic Factor of Long Term Outcome in Non-Small Cell Lung Cancer Patients
Authors: Li Hang , Li Bin , Pan Yunjian , Zhang Yang , Xiang Jiaqing , Zhang Yawei , Sun Yihua , Yu Xiang , He Wei , Hu Hong 
Published: January 2021

BackgroundSurgical resection is often the preferred treatment for non-small cell lung cancer (NSCLC) patients. Predictive biomarkers after surgery can help monitoring and treating patients promptly, so as to improve the clinical outcome. In this study, we evaluated one potential candidate biomarker, the folate receptor-positive circulating tumor cell (FR+CTC), by investigating its prognostic and predictive significance in NSCLC patients who underwent surgery.MethodsIn this prospective, observational study, we enrolled NSCLC patients who were eligible to receive surgery. Prior to operation, peripheral blood was collected from each patient for an FR+CTC analysis. FR+CTCs were isolated by negative enrichment using immunomagnetic beads to deplete leukocytes and then quantitatively detected by a ligand-targeted polymerase chain reaction (PCR) method. These patients were then given standard care and were actively followed up for seven years. At the end of the follow-up period, the association between the FR+CTC level and the prognosis in these patients was evaluated.ResultsOverall, preoperative FR+CTC level was not significantly different among NSCLC patients with adenocarcinoma or non-adenocarcinoma subtypes (P = 0.24). However, between patients with low- and high-risk pathological adenocarcinoma subtypes, the preoperative FR+CTC level was significantly different (P = 0.028). Further, patients with lower preoperative FR+CTC level had longer relapse-free survival (RFS) and overall survival (OS) than those with higher preoperative FR+CTC level (RFS: not reached vs. 33.3 months, P = 0.018; OS: not reached vs. 72.0 months, P = 0.13). In a multivariate COX regression analysis, FR+CTC level (HR = 4.10; 95% CI, 1.23–13.64; P=0.022) and pathological stage (HR = 3.16; 95% CI, 1.79–10.14; P = 0.0011) were independent prognostic factors of RFS. Moreover, FR+CTC level together with adenocarcinoma subtypes provided additional information on risk for disease recurrence compared with FR+CTC or adenocarcinoma subtype alone.ConclusionOur study demonstrated that the preoperative FR+CTC level was a potential predictor for the prognosis of NSCLC patients underwent surgery. Further, when preoperative FR+CTC level is considered together with primary tumor proliferation characteristics, its prognostic value supplements that of these conventional pathological features.