bluuebunny/crossref_metadata_2025_split huggingface dataset:
Co2FeAl Full Heusler Compound Based Spintronic Terahertz Emitter
Authors: Gupta Rahul , Husain Sajid , Kumar Ankit , Brucas Rimantas , Rydberg Anders , Svedlindh Peter 
Published: March 2021

AbstractTo achieve a large terahertz (THz) amplitude from a spintronic THz emitter (STE), materials with 100% spin polarisation such as Co‐based Heusler compounds as ferromagnetic layer are required. However, these compounds are known to loose their half‐metallicity in the ultrathin film regime, as it is difficult to achieve L21 ordering, which has become a bottleneck for the film growth. Here, the successful deposition using room temperature DC sputtering of the L21 and B2 ordered phases of the Co2FeAl full Heusler compound is reported. Co2FeAl is used as ferromagnetic layer together with highly orientated Pt as nonferromagnetic layer in the Co2FeAl/Pt STE, where an MgO (10 nm) seed layer plays an important role to achieve the L21 and B2 ordering of Co2FeAl. The THz generation in the Co2FeAl/Pt STE is presented, which has a bandwidth of 0.2–4 THz. The THz electric field amplitude is optimized with respect to thickness, orientation, and growth parameters using a thickness dependent model considering the optically induced spin current, superdiffusive spin current, inverse spin Hall effect, and the THz attenuation in the layers. This study, based on the full Heusler Co2FeAl compound opens up a plethora of possibilities in STE research involving full Heusler compounds.
Multifunctional Stretchable Organic–Inorganic Hybrid Electronics with Transparent Conductive Silver Nanowire/Biopolymer Hybrid Films
Authors: Park Sung Bin , Han Joo Won , Kim Jung Ha , Wibowo Anky Fitrian , Prameswati Ajeng , Park Jihyun , Lee Jonghee , Moon Myoung‐Woon , Kim Min‐Seok , Kim Yong Hyun 
Published: March 2021

AbstractStretchable organic electronics open opportunities for novel applications in next‐generation intelligent electronics, such as human‐friendly, skin‐attachable, and implantable devices. Stretchable transparent electrodes with appropriate electrical, mechanical, and optical properties as well as high conformability to curved surfaces and human skin are key components of wearable and implantable devices. Herein, a silver nanowire (AgNW)‐embedded chitosan biopolymer hybrid film is presented as a high‐performance stretchable transparent electrode. The introduction of an organic surface modifier and embedding the AgNW network results in remarkably improved adhesion between the nanowires and substrate; consequently, the electrical properties and mechanical performance of the stretchable films are improved simultaneously. The fabricated hybrid films show high transmittance (89.0% at 550 nm), low sheet resistance (8.4 ohm sq−1), and limited resistance change under tensile strains. Moreover, these stretchable transparent electrodes with versatile applicability are integrated into multifunctional stretchable electronic devices such as heaters, strain sensors, and light‐emitting devices, which show excellent thermal, strain sensing, and light‐emitting properties, respectively. In addition, they conform to curved surfaces or human skin and maintain their mechanical robustness. The proposed strategy offers new opportunities for stretchable and biocompatible organic electronics, particularly for skin‐attachable, visually imperceptible thermal management devices, strain sensors, and light‐emitting devices.
Bio‐Inspired Multi‐Mode Pain‐Perceptual System (MMPPS) with Noxious Stimuli Warning, Damage Localization, and Enhanced Damage Protection
Authors: Li Fali , Gao Shuang , Lu Ying , Asghar Waqas , Cao Jinwei , Hu Chao , Yang Huali , Wu Yuanzhao , Li Shengbin , Shang Jie , Liao Meiyong , Liu Yiwei , Li Run‐Wei 
Published: March 2021

AbstractThe multi‐mode pain‐perceptual system (MMPPS) is essential for the human body to perceive noxious stimuli in all circumstances and make an appropriate reaction. Based on the central sensitization mechanism, the MMPPS can switch between different working modes and thus offers a smarter protection mechanism to human body. Accordingly, before injury MMPPS can offer warning of excessive pressure with normal pressure threshold. After injury, extra care on the periphery of damage will be activated by decreasing the pressure threshold. Furthermore, the MMPPS will gradually recover back to a normal state as damage heals. Although current devices can realize basic functions like damage localization and nociceptor signal imitating, the development of a human‐like MMPPS is still a great challenge. Here, a bio‐inspired MMPPS is developed for prosthetics protection, in which all working modes is realized and controlled by mimicking the central sensitization mechanism. Accordingly, the system warns one of a potential injury, identifies the damaged area, and subsequently offers extra care. The proposed system can open new avenues for designing next‐generation prosthetics, especially make other smart sensing systems operate under complete protection against injuries.
Incidence of acute myocardial infarction in the workforce: Findings from the Occupational Disease Surveillance System
Authors: Troke Natalie , Logar‐Henderson Chloë , DeBono Nathan , Dakouo Mamadou , Hussain Selena , MacLeod Jill S. , Demers Paul A. 
Published: March 2021

AbstractBackgroundIncreased risks of acute myocardial infarction (AMI) may be attributable to the workplace, however, associations are not well‐established. Using the Occupational Disease Surveillance System (ODSS), we sought to estimate associations between occupation and industry of employment and AMI risk among workers in Ontario, Canada.MethodsThe study population was derived by linking provincial accepted lost‐time workers' compensation claims data, to inpatient hospitalization records. Workers aged 15–65 years with an accepted non‐AMI compensation claim were followed for an AMI event between 2007 and 2016. Adjusted Cox proportional hazard models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for each industry and occupation group, compared to all other workers in the cohort. Sex‐stratified analyses were also performed.ResultsIn all, 24,514 incident cases of AMI were identified among 1,502,072 Ontario workers. Increased incidence rates of AMI were found across forestry (HR 1.37, 95% CI 1.19–1.58) and wood processing (HR 1.50, 1.27–1.77) job‐titles. Elevated rates were also detected within industries and occupations both broadly related to mining and quarrying (HR 1.52, 1.17–1.97), trucking (HR 1.32, 1.27‐1.38), construction (HR 1.32, 1.14–1.54), and the manufacturing and processing of metal (HR 1.41, 1.19–1.68), textile (HR 1.41, 1.07–1.88), non‐metallic mineral (HR 1.30, 0.82–2.07), and rubber and plastic (HR 1.42, 1.27–1.60) products. Female food service workers also had elevated AMI rates (HR 1.36, 1.23–1.51).ConclusionThis study found occupational variation in AMI incidence. Future studies should examine work‐related hazards possibly contributing to such excess risks, like noise, vibration, occupational physical activity, shift work, and chemical and particulate exposures.
Stereoselective Synthesis of Cyclohepta[b]indoles by Visible‐Light‐Induced [2+2]‐Cycloaddition/retro‐Mannich‐type Reactions
Authors: Mu Xin‐Peng , Li Yuan‐He , Zheng Nan , Long Jian‐Yu , Chen Si‐Jia , Liu Bing‐Yan , Zhao Chun‐Bo , Yang Zhen 
Published: March 2021

AbstractA novel method for the concise synthesis of cyclohepta[b]indoles in high yields was developed. The method involves a visible‐light‐induced, photocatalyzed [2+2]‐cycloaddition/ retro‐Mannich‐type reaction of enaminones. Experimental and computational studies suggested that the reaction is a photoredox process initiated by single‐electron oxidation of an enaminone moiety, which undergoes subsequent cyclobutane formation and rapidly fragmentation in a radical‐cation state to form cyclohepta[b]indoles.
Nanofluid of magnetic‐activated charcoal and hydrophobic deep eutectic solvent: Application in dispersive magnetic solid‐phase extraction for the determination and preconcentration of warfarin in biological samples by high‐performance liquid chromatography
Authors: Nooraee Nia Negar , Hadjmohammadi Mohammad Reza 
Published: March 2021

AbstractIn this study, for the first time, nanofluid of magnetic‐activated charcoal and hydrophobic deep eutectic solvent (AC@Fe3O4–DES) based dispersive magnetic solid‐phase extraction was successfully applied for the determination and preconcentration of warfarin in plasma and urine samples. The hydrophobic DES was prepared by mixing tetramethylammonium chloride (as hydrogen bond acceptor) and thymol (as hydrogen bond donor) and acted simultaneously as both carrier and stabilizer for magnetic nanoparticles. In this method, the nanofluid as a new extraction solvent was rapidly injected into the aqueous sample, which led to improvement of the mass transfer of the analytes into the sorbent and reduction of the extraction time. In the screening step, the fractional factorial design was applied for selecting some important parameters which significantly affected the extraction procedure. The effective parameters were then optimized by Box–Behnken design. Under the optimal conditions, the limits of detection were in the range of 0.3–1.6 ng/ml. A good linear range was observed in the range of 1.0–500.0 ng/ml for water and 5.0–500.0 ng/ml for urine and plasma. The intra‐ and inter‐day relative standard deviations were 2.7–3.2 and 1.9–4.5% for five replications, respectively. Based on the results, the proposed method was successfully applied for the determination of warfarin in biological samples, using high‐performance liquid chromatography.
Response to pegylated interferon in a COVID‐19–positive elderly woman with primary myelofibrosis treated with ruxolitinib
Authors: Frankel Arthur E. , Reddy Renuka , DeSuza Kayla R. , Deeb Khaled , Carlin Aaron F. , Smith Davey , Xie Yushuang , Naik Eknath , Silver Richard T. , Hasselbalch Hans C. 
Published: March 2021

AbstractAn 83‐year‐old female had asymptomatic SARS‐CoV‐2 infection while taking ruxolitinib. She remained RT‐PCR positive for viral RNA for >120 days, and Pegylated interferon for 4 weeks led to viral RNA clearance. The observations support combination therapy of ruxolitinib + interferon for COVID‐19.
Hemophagocytic lymphohistiocytosis presented with fever of unknown origin: A case study and literature review
Authors: Hakamifard Atousa , Mardani Masoud , Gholipur‐Shahraki Tahereh 
Published: March 2021

AbstractHemophagocytic lymphohistiocytosis (HLH) is a rare and life‐threatening clinical syndrome, which may present with FUO. The possible diagnosis of HLH must be considered in the differential diagnosis when a patient presents with FUO.
Left internal mammary artery injury and subsequent hypovolemic shock due to a hemothorax after subxiphoid pericardiocentesis in a postoperative cardiac surgery patient
Authors: Oudeman Maurice A. P. , Planken R. Nils , Beijk Marcel A. M. 
Published: March 2021

AbstractMultimodality imaging is recommended in patients in shock after seemingly uneventful pericardiocentesis. The aim of this study was to heighten awareness that LIMA injury can lead to a life‐threatening hemothorax in postoperative cardiac surgery patients.
An Efficient Oxygen Reduction Catalyst for Zn‐Air Battery: Cobalt Nanoparticles Encapsulated in 3D Nitrogen‐Doped Porous Carbon Networks Derived from Fish Scales
Authors: Sun Jiankang , Qiu Xiaoyu , Wang Zhengyun , Peng Zhuo , Jiang Lipei , Li Guangfang , Wang Haitao , Liu Hongfang 
Published: March 2021

AbstractThe development of a simple and eco‐friendly approach for synthesizing high‐activity and low‐cost electrocatalysts remains a huge challenge for the commercialization of zinc‐air battery technology. Herein, a facile method is demonstrated to skillfully fabricate cobalt nanoparticles encapsulated in N‐doped micro/mesoporous carbon networks (Co/N‐MC) by using natural fish scales as carbon source. The effects of pyrolysis temperature on microstructure, N‐doping and oxygen reduction reaction (ORR) electrocatalytic activity of the obtained Co/N‐MC samples are systematically investigated. The as‐synthesized Co/N‐MC catalyst exhibits better ORR catalytic activity, stability as well as superior Zn‐air battery performance compared with commercial 20 % Pt/C catalyst, owing to its three‐dimensional structures and synergistic effect of N species. The simple and eco‐friendly strategy developed for ORR catalyst in this study holds great potential for the commercial application of zinc‐air batteries.
Removal of phenolics from aqueous pyrolysis condensate by activated biochar
Authors: Sarchami Tahereh , Batta Neha , Rehmann Lars , Berruti Franco 
Published: March 2021

AbstractAqueous pyrolysis condensate (APC) is rich in acetic acid and has been utilized as feedstock for anaerobic digestion to produce biogas. However, various phenolic compounds dissolved in the APC act as inhibitors, negatively affecting the anaerobic digestion. In this work, we have investigated the feasibility of employing pyrolytic biochar as an adsorbent for the selective removal of phenolics from APC. Biochars derived from the pyrolysis of soft wood, rice husks, and sewage sludge and their respective activated forms have been tested as potential adsorbents for the removal of pure phenol from water solutions. The experimental results showed that, among the adsorbents studied, activated soft wood (ASW) biochar has the highest adsorption efficiency and capacity for phenol removal from water. The kinetic and isotherm studies showed that the phenol adsorption data with ASW biochar may be well described by pseudo second‐order equation and Freundlich model. Batch experiments were carried out to investigate the effects of pH, adsorbent loading, contact time, and temperature on phenolics adsorption onto ASW from APC. At optimal adsorption conditions (pH of 6.0, contact time of 30 min, adsorbent loading of 9.61 , and temperature of 25°C), an adsorption efficiency of 96.9% ± 1.8% and a capacity of 100.78 ± 2.7 mg · g−1 were achieved. Finally, the adsorption efficiency and capacity of ASW for phenolics removal from APC was successfully compared with those of commercial activated carbon, showing comparable results, which indicated the suitability of ASW as an environmentally friendly adsorbent.
Forecasting hyponatremia in hospitalized patients using multilayer perceptron and multivariate linear regression techniques
Authors: Theerthagiri Prasannavenkatesan 
Published: March 2021

SummaryThe percentage of patients hospitalized due to hyponatremia is getting higher. Hyponatremia is the deficiency of sodium electrolyte in the human serum. This deficiency might indulge adverse effects and also be associated with longer hospital stay or mortality if it was not actively treated and managed. This work predicts the futuristic sodium levels of patients based on their history of health problems using a multilayer perceptron (MLP) and multivariate linear regression (MLR) algorithm. This work analyzes the patient's age, information about other diseases such as diabetes, pneumonia, liver disease, malignancy, pulmonary, sepsis, SIADH, and a sodium level of the patient during admission to the hospital. The results of the proposed MLP algorithm is compared with the MLR algorithm‐based results. The MLP prediction results generate 23%–72% of higher prediction results than the MLR algorithm. Thus, the proposed MLP algorithm has produced 57.1% of the reduced mean squared error rate than the MLR results on predicting future sodium ranges of patients. Further, the proposed MLP algorithm produces 27%–50% of the higher prediction precision rate. Therefore, the MLP algorithm can be used for forecasting patient's hyponatremia.
VS38 staining contributes to a novel gating strategy in flow cytometry for small B cell lymphoma, especially in lymphoplasmacytic lymphoma/Waldenström macroglobulinemia
Authors: Mizuta Shumpei , Yamane Noriko , Mononobe Saya , Watanabe Asami , Matsuki Shinichiro , Komai Takao , Koba Yusuke , Mitani Sachiko , Kawata Takahito , Tamekane Akira , Watanabe Mitsumasa 
Published: March 2021

AbstractBackgroundMulti‐parametric flow cytometry (MFC) is a helpful tool for detecting neoplastic cells in malignant lymphoma; however, lymphoma cells can be difficult to detect when characteristic immunophenotypic abnormalities are not evident. We evaluated the stainability of VS38, which is used for multiple myeloma, in normal and abnormal B cells using MFC to develop a new strategy for detecting lymphoma cells.MethodsWe compared the median fluorescence intensity of VS38 staining in lymphocytes from patients without hematopoietic neoplasms and in B cells from 26 patients with B cell lymphoma (BCL). To evaluate the performance of VS38 gating, we compared VS38‐positive B cells with the percentages of BCL cells, and with the mutation ratios of MYD88 L265P measured by droplet digital PCR in patients with lymphoplasmacytic lymphoma (LPL)/Waldenström macroglobulinemia (WM).ResultsCD27‐positive memory B cells were stained with VS38, whereas normal lymphocytes were faintly stained. Lymphoma cells were stained with VS38 in 11 of 12 patients with LPL/WM, 3 of 3 with chronic lymphocytic leukemia, 3 of 5 with mantle cell lymphoma, 2 of 4 with follicular lymphoma, and 1 of 1 with splenic marginal zone lymphoma. The percentages of VS38‐positive B cells in VS38‐positive BCL were equivalent to those of lymphoma cells and the mutation ratios of MYD88 L265P in LPL/WM.ConclusionsVS38 identified neoplastic cells in plasma cell disorders and BCL. This might improve the accuracy of BCL diagnosis, especially in patients with LPL/WM.
High Pressure Synthesis of the Spin Chain Sulfide Ba9V3S11(S2)2
Authors: Almoussawi Batoul , Tomohiri Hayashi , Kageyama Hiroshi , Kabbour Houria 
Published: March 2021

AbstractThe new compound Ba9V3S11(S2)2 was synthesized using high pressure and high temperature. The single crystal XRD based structure solution and refinement show that it crystallizes in the hexagonal system with the space group P‐6c2 (188) and the lattice parameters a=9.1979(4) Å and c=18.0462(10) Å. Its one‐dimensional structure is related to the high‐pressure phase Ba9V3Se15 (Ba9V3Se11(Se2)2) and consists of chains made of face‐sharing VS6 octahedra running along the c‐axis. The chains contain two distinct sites of Vanadium with a mixed valence state of V3+ and V2+. The space between the chains, two type of columns, is occupied by disulfides (S2)2− pairs and isolated sulfide anions S2− surrounded by Ba2+ cations. The distributions within the columns are slightly different than in Ba9V3Se11(Se2)2 making the two compounds not strictly isostructural but analogues with the same symmetry and unit cell. We discuss this phase on the basis of crystallochemical analysis and DFT calculated electronic structure. Assuming a magnetic insulator as found from DFT+U calculations, we discuss the existence of magnetic clusters within the spin chains.
Preoperative sleep quality and adverse pain outcomes after total hip arthroplasty
Authors: Bjurström Martin F. , Irwin Michael R. , Bodelsson Mikael , Smith Michael T. , Mattsson‐Carlgren Niklas 
Published: March 2021

AbstractBackgroundSleep disturbance is thought to aggravate acute postoperative pain. The influence of preoperative sleep problems on pain control in the long‐term and development of chronic postsurgical pain is largely unknown.MethodsThis prospective, observational study aimed to examine the links between preoperative sleep disturbance (Pittsburgh Sleep Quality Index, PSQI) and pain severity (Brief Pain Inventory, BPI) 6 months postoperative (primary outcome), objective measures of pain and postoperative pain control variables (secondary outcomes). Patients (n = 52) with disabling osteoarthritis (OA) pain undergoing total hip arthroplasty (THA) were included. Quantitative sensory testing (QST) was performed preoperatively on the day of surgery to evaluate pain objectively. Clinical data, as well as measures of sleep quality and pain, were obtained preoperatively and longitudinally over a 6‐month period.ResultsPreoperatively, sleep disturbance (i.e., PSQI score >5) occurred in 73.1% (n = 38) of THA patients, and pain severity was high (BPI pain severity 5.4 ± 1.3). Regression models, adjusting for relevant covariates, showed that preoperative PSQI score predicted pain severity 6 months postoperative (β = 0.091 (95% CI 0.001–0.181), p = .048, R2 = 0.35). Poor sleep quality was associated with increased pressure pain sensitivity and impaired endogenous pain inhibitory capacity (R2 range 0.14–0.33, all p's < 0.04). Moreover, preoperative sleep disturbance predicted increased opioid treatment during the first 24 hr after surgery (unadjusted β = 0.009 (95% CI 0.002–0.015) mg/kg, p = .007, R2 = 0.15).ConclusionsPreoperative sleep disturbance is prevalent in THA patients, is associated with objective measures of pain severity, and independently predicts immediate postoperative opioid treatment and poorer long‐term pain control in patients who have undergone THA.SignificancePoor sleep quality and impaired sleep continuity are associated with heightened pain sensitivity, but previous work has not evaluated whether preoperative sleep problems impact long‐term postoperative pain outcomes. Here, we show that sleep difficulties prior to total hip arthroplasty adversely predict postoperative pain control 6 months after surgery. Given sleep difficulties robustly predict pain outcomes, targeting and improving sleep may have salutary effects on postoperative pain reports and management.
In Vitro Screening of 21 Bisphenol A Replacement Alternatives: Compared with Bisphenol A, the Majority of Alternatives Are More Cytotoxic and Dysregulate More Genes in Avian Hepatocytes
Authors: Crump Doug , Sharin Tasnia , Chiu Suzanne , O'Brien Jason M. 
Published: March 2021

Abstract
An avian in vitro screening approach was used to determine the effects of 21 bisphenol A (BPA) alternatives. Cytotoxicity and dysregulation of genes associated with estrogen response and other toxicologically relevant pathways evoked by these alternatives were compared with BPA. Most of the BPA alternatives (15/21) were equally or more cytotoxic than BPA in chicken embryonic hepatocytes; variability in cell viability was associated with chemical structure and the log octanol–water partition coefficient (logP) values. A negative linear relationship (r 2 = 0.745; p = 0.49–07; n = 18) was observed between logP and the log median lethal concentration (logLC50) values. The least cytotoxic BPA alternatives elicited the greatest gene dysregulation and, overall, most of the alternatives altered more genes than BPA (measured with a custom polymerase chain reaction array). This overall approach shows promise for use as a screen for hazard-based prioritization of BPA replacement alternatives and to ideally identify those that may be less harmful and/or require additional toxicity testing. Environ Toxicol Chem 2021;40:2024–2031. © 2021 Her Majesty the Queen in Right of Canada Environmental Toxicology and Chemistry © 2021 SETAC. Reproduced with the permission of the Minister of Environment and Climate Change Canada.