bluuebunny/crossref_metadata_2025_split huggingface dataset:
The experience of implementation of polymer flooding technology at Zaburunye oil filed as a method for developing mature fields
Authors: Musayev M. Sh. , Musharova D. A. , Zhappasbayev B. Zh. , Orynbassar E. K. 
Published: December 2021

In conditions of high depletion of oil fields and volatile oil prices, methods of enhanced oil recovery are becoming especially relevant, the use of which contributes to an increase in the oil recovery factor in addition to the use of secondary oil recovery methods. One of the technologies allowing to increase the oil recovery factor is polymer flooding technology, the distinctive advantage of which in comparison with other chemical methods is a wide range of application conditions and design variability during implementation.
This paper presents the results of the application of polymer flooding technology in the oil field of Kazakhstan Zaburunye, which is in the high water-cut stage. To determine the strategy for the further implementation of polymer flooding technology and in order to find the optimal predictive development options, calculations were carried out on the developed hydrodynamic model.
Analysis of the efficiency of multizone selective completion for the operation of oil producing wells at the Zhetybai field
Authors: Utemissova L. G. , Tlegenov B. B. , Minikayev F. M. 
Published: December 2021

The article discusses the multizone selective completion for the operation of oil producing wells and shows its positive and negative aspects.
The authors were given the task of assessing the application of the technology of the multizone selective completion for the operation of oil producing wells at the Zhetybai field. The authors reviewed candidate well for application the multizone selective completion and concluded that the proposed project of multizone selective completion for the operation of oil producing wells is economically attractive due to additional oil production and a low payback period. Thy also assessed the prospects of implementation, in terms of the number of required installations and additional oil production.
Tracce dell’organizzazione di una figlina imperiale a Mursa
Authors: Vitelli Casella Mattia 
Published: December 2021

This article aims at investigating the administration, the economic activities and the evolution of an imperial estate epigraphically attested in ancient Mursa, in Pannonia inferior, along the Drava river. Particularly, there are evidences of imperial slaves engaged in business management as well as many stamped bricks with different inscriptions. By matching these two types of epigraphs, it can be sketched that the property began its activities between the 1st and 2nd century AD, reached its maximum bricks production under Hadrian, in connection with the establishment of the colony, and went on until a sudden stop due to the Marcomannic invasion. Now, we are quite sure that the production resumed under the Severian dynasty, even if we do not know for how long it continued in the 3rd century, as is the case of neighboring provinces.
A Comparative Assessment on Antioxidant and Phytochemical of Trichilia monadelpha (Thonn) J.J. De Wilde (Meliaceae) Plant Extracts
Authors: Clark P. D. , Omo-Udoyo E. 
Published: December 2021

This study was designed to evaluate the phytochemical screening and antioxidant activities of Trichilia monadelpha plant extracts. The leaves were extracted using two different solvents namely-(n-hexane and methanol). The dry or wet yield of n-hexane extract was 1.3%, while methanolic extract exhibited a percentage yield of 3.7 %. Phytochemical research revealed the presence of secondary plant metabolites such as; alkaloids, flavonoids, cardiac glycosides, terpenoids and saponins. In-vitro antioxidant activity was determined using three assays (DPPH free radical scavenging assay, reducing ability and hydroxy radical scavenging activity) with four concentrations (0.25, 5.0, 1.0 and 2.0 mg/L), vitamin C was also used as a standard antioxidant.
The percentage of inhibition was measured, and the results from all assay models showed a concentration-dependent percentage of inhibition by the methanol extract. However, the percentage values for the 2,2, -diphenyl-1-picrylhydrazyl (DPPH), reducing ability and hydroxy radical scavenging activity assays of T. monadelpha leaf was lower than that of standard vitamin C. The Pearson’s correlation coefficient was evaluated and the results showed that of the two extracts, the methanolic extract had the most antioxidant activity with the methanol extract exhibiting a better significant correlation that had a similar trend to that of the antioxidant compound (vitamin C). The results of this study have shown that the plant Trichilia monodelpha contains bioactive compounds which may have contributed to its antioxidant properties.
Biodegradable Metal–Organic‐Framework‐Gated Organosilica for Tumor‐Microenvironment‐Unlocked Glutathione‐Depletion‐Enhanced Synergistic Therapy
Authors: Ma Yuanyuan , Su Zheng , Zhou Liming , He Liangcan , Hou Zhenyu , Zou Jianhua , Cai Yu , Chang Di , Xie Jinbing , Zhu Chen , Fan Wenpei , Chen Xiaoyuan , Ju Shenghong 
Published: December 2021

AbstractThe clinical employment of cisplatin (cis‐diamminedichloroplatinum(II) (CDDP)) is largely constrained due to the non‐specific delivery and resultant serious systemic toxicity. Small‐sized biocompatible and biodegradable hollow mesoporous organosilica (HMOS) nanoparticles show superior advantages for targeted CDDP delivery but suffer from premature CDDP leakage. Herein, the smart use of a bimetallic Zn2+/Cu2+ co‐doped metal–organic framework (MOF) is made to block the pores of HMOS for preventing potential leakage of CDDP and remarkably increasing the loading capacity of HMOS. Once reaching the acidic tumor microenvironment (TME), the outer MOF can decompose quickly to release CDDP for chemotherapy against cancer. Besides, the concomitant release of dopant Cu2+ can deplete the intracellular glutathione (GSH) for increased toxicity of CDDP as well as catalyzing the decomposition of intratumoral H2O2 into highly toxic •OH for chemodynamic therapy (CDT). Moreover, the substantially reduced GSH can also protect the yielded •OH from scavenging and thus greatly improve the •OH‐based CDT effect. In addition to providing a hybrid HMOS@MOF nanocarrier, this study is also expected to establish a new form of TME‐unlocked nanoformula for highly efficient tumor‐specific GSH‐depletion‐enhanced synergistic chemotherapy/chemodynamic therapy.
Boosting Charge Transport in BiVO4 Photoanode for Solar Water Oxidation
Authors: Lu Yuan , Yang Yilong , Fan Xinyi , Li Yiqun , Zhou Dinghua , Cai Bo , Wang Luyang , Fan Ke , Zhang Kan 
Published: December 2021

AbstractThe ability to regulate charge separation is pivotal for obtaining high efficiency of any photoelectrode used for solar fuel production. Vacancy engineering for metal oxide semiconductor photoelectrode is a major strategy but has faced a formidable challenge in bulk charge transport because of the elusive charge self‐trapping site. In this work, a new deep eutectic solvent to engineer bismuth vacancies (Bivac) of BiVO4 photoanode is reported; the novel Bivac can remarkably increase the charge diffusion coefficient by 5.8 times (from 1.82 × 10−7 to 1.06 × 10−6 cm2 s−1), which boosts the charge transport efficiency. Through further loading CoBi cocatalyst to enhance charge transfer efficiency, the photocurrent density of BiVO4 photoanode with optimal Bivac concentration reaches 4.5 mA cm−2 at 1.23 V vs reversible hydrogen electrode under AM 1.5 G illumination, which is higher than that of previously reported Ovac engineered BiVO4 photoanode where the BiVO4 photoanode is synthesized by a similar procedure. This work perfects a cation defect engineering that enables the potential capability to equate the charge transport properties in different types of semiconductor materials for solar fuel conversion.
Endogenous Electric‐Field‐Coupled Electrospun Short Fiber via Collecting Wound Exudation
Authors: Wang Juan , Lin Jiawei , Chen Liang , Deng Lianfu , Cui Wenguo 
Published: December 2021

AbstractEndogenous electric fields (EF) are the basis of bioelectric signal conduction and the priority signal for damaged tissue regeneration. Tissue exudation directly affects the characteristics of endogenous EF. However, current biomaterials lead to passive repair of defect tissue due to limited management of early wound exudates and inability to actively respond to coupled endogenous EF. Herein, the 3D bionic short‐fiber scaffold with the functions of early biofluid collection, response to coupled endogenous EF, is constructed by guiding the short fibers into a 3D network structure and subsequent multifunctional modification. The scaffold exhibits rapid reversible water absorption, reaching maximum after only 30 s. The stable and uniform distribution of polydopamine‐reduced graphene oxide endows the scaffold with stable electrical and mechanical performances even after long‐term immersion. Due to its unique ‐ bionic structure and tissue affinity, the scaffold further acts as an “electronic skin,” which transmits endogenous bioelectricity via absorbing wound exudates, promoting the treatment of diabetic wounds. Furthermore, under the endogenous EF, the cascade release of vascular endothelial growth factor accelerates the healing process. Thus, the versatile scaffold is expected to be an ideal candidate for repairing different defect tissues, especially electrosensitive tissues.
Recent Developments of Superhydrophobic Surfaces (SHS) for Underwater Drag Reduction Opportunities and Challenges
Authors: Feng Xiaoming , Sun Pengfei , Tian Guizhong 
Published: December 2021

AbstractSuperhydrophobic surfaces (SHS) for underwater drag reduction draw more and more attention owing to its promising and wide applications such as underwater vehicles, pipeline oil transportation, and aquaculture. However, the drag reduction properties are inextricably linked to the stability of air layer on SHS. This review highlights recent advances regarding SHS for underwater drag reduction in the past three years. First, the fundamental theories are briefly described. Next, the crucial influencing factors, which include dimension and arrangement of particles, layout, and shape of the microstructures, Reynolds number, and attack angle on underwater drag reducing performance of SHS are thoroughly listed. Furthermore, the superior or inferior of these manufacturing techniques is also individually illustrated. After that, the solutions of enhancing stability of the air layer are explicitly classified. Then, the practical applications and its potential value in ships and underwater vehicles, microchannels, as well as fabrics are briefly discussed. Finally, the remaining challenges and promising breakthroughs in the field of SHS for underwater drag reduction are clarified in depth.
Pressure Drop Measurements in Microfluidic Devices: A Review on the Accurate Quantification of Interfacial Slip
Authors: Vega‐Sánchez Christopher , Neto Chiara 
Published: December 2021

AbstractThe correct theoretical definition of boundary conditions of flow underpins all fluid dynamics studies, and is particularly important in situations in which the flow is confined on the nano‐ and micro‐scale. Microfluidic devices are an excellent platform to measure boundary flow conditions, and the pressure drop versus flow rate method is particularly useful in detecting evidence of microscale interfacial slip and drag reduction. This review focuses on the pressure drop method, identifying the main experimental parameters affecting the accuracy and reproducibility of microfluidic experiments of slip, quantifying the magnitude and source of common errors, and providing practical solutions and guidelines. A summary of literature results of interfacial slip obtained with pressure drop measurements in microfluidic devices is also provided, and the slip results are directly compared to expected slip models. This review serves as an introduction for new researchers moving into the field of interfacial slip, and as reminder for established researchers of the need to create highly controlled experimental procedures in order to obtain reproducible and reliable measurements of boundary flow conditions. A direct comparison of accurate experiments with theoretical models is bound to bring about clarity about the mechanisms of slip on smooth and structured surfaces.
Diblock and Random Antifouling Bioactive Polymer Brushes on Gold Surfaces by Visible‐Light‐Induced Polymerization (SI‐PET‐RAFT) in Water
Authors: Kuzmyn Andriy R. , Teunissen Lucas W. , Fritz Pina , van Lagen Barend , Smulders Maarten M. J. , Zuilhof Han 
Published: December 2021

AbstractSurface‐initiated photoinduced electron‐transfer‐reversible addition–fragmentation chain transfer (SI‐PET‐RAFT) is, for the first time, used for the creation of antifouling polymer brushes on gold surfaces based on three monomers: oligo(ethylene glycol) methyl ether methacrylate (MeOEGMA), N‐(2‐hydroxypropyl) methacrylamide (HPMA), and carboxybetaine methacrylamide (CBMA). These coatings are subsequently characterized by X‐ray photoelectron spectroscopy (XPS) and ellipsometry. The living nature of this polymerization allows for the creation of random and diblock copolymer brushes, which are based on HPMA (superb antifouling) and CBMA (good antifouling and functionalizable via activated ester chemistry). The polymer brushes demonstrate good antifouling properties against undiluted human serum, as monitored by quartz crystal microbalance with dissipation (QCM‐D) and surface plasmon resonance (SPR) spectroscopy in real time. The amount of immobilization of bioactive moieties, here an antibody immobilized using N‐succinimidyl ester–1‐ethyl‐3‐(3‐dimethylaminopropyl)carbodiimide hydrochloride (NHS–EDC) coupling, in the diblock and random copolymer brushes is monitored by SPR, and is analyzed with respect to the brush structure, and is shown to be superior in the diblock copolymer brush. This approach represents a scalable, robust, mild, oxygen‐tolerant, and heavy‐metal‐free route toward the production of antifouling and functional copolymer brushes (on gold surfaces) that open up applications in biosensing and tissue engineering.
Anion‐Decoordination Cell Formation Process Stabilizes Dual Electrodes for Long‐Life Quasi‐Solid‐State Lithium Metal Battery
Authors: Wang Hao‐Ran , Yang Ya‐Nan , Bai Fan , Zhang Tao 
Published: December 2021

AbstractCompared with the complete replacement of liquid electrolytes by solid electrolytes, the hybrid quasi‐solid electrolyte (HQSE) has more practical application potential due to its high thermal stability and high ionic conductivity as well as good interface wettability. In this work, a HQSE film is prepared using the Li6.40La3Zr1.40Ta0.60O12 (LLZTO) nanoparticles localized composite liquid electrolyte (CLE) composed of TEGDME (0.5 m LiTFSI) organic electrolyte and Pyr14TFSI ionic liquid. The HQSE film exhibits high ionic conductivity of 1.77 × 10−3 S cm–1 and a high Li‐ion transference number of 0.56 at 25 °C. More importantly, a formation process is designed by utilizing the oxidative decomposition of the free TFSI– anions caused by the substitution of ion cluster Li(TFSI)n+1n− by Li(TEGDME)x+ in HQSE, achieving the in‐situ construction of the stable and complete cathode electrolyte interface and solid electrolyte interface in the cathode and anode simultaneously, and benefiting from the liquid electrolyte being confined to the surface of LLZTO particles, the HQSE film finally exhibits high stability to the dual electrodes, ensuring that the quasi‐solid‐state Li metal battery exhibits capacity retention of 80% after 1000 cycles at 0.2 C rate, and 90% after 500 cycles at 0.5 C rate.
Evaluations of S‐Metolachlor in flue‐cured tobacco weed management programs
Authors: Clapp Andrew M. , Vann Matthew C. , Cahoon Charles W. , Jordan David L. , Fisher Loren R. , Inman Matt D. 
Published: December 2021

AbstractEffective weed control is critical to growth and development of flue‐cured tobacco; however, current herbicide options are limited in commercial production. Field experiments were conducted from 2017 to 2018 to evaluate S‐metolachlor for use in flue‐cured tobacco weed management programs. Treatments included 10 herbicide programs: pretransplanted incorporated (PTI) applications of S‐metolachlor (1.07 kg a.i. ha–1) alone or in various combinations with sulfentrazone (0.18 kg a.i. ha–1), clomazone (0.84 kg a.i. ha–1), and pendimethalin (0.79 kg a.i. ha–1). S‐metolachlor and pendimethalin were also applied posttransplanting directed to row middles (POST‐DIR) following PTI applications of sulfentrazone + clomazone. A single posttransplanting over‐the‐top (POST‐OT) application of S‐metolachlor and a non‐treated control were included for comparison. The inclusion of S‐metolachlor in PTI herbicide programs did not improve weed control beyond the combination of sulfentrazone + clomazone. However, weed control after final harvest was improved by 8%, when S‐metolachlor was applied POST‐DIR. S‐metolachlor applied POST‐OT caused injury to tobacco plants (12%), although symptoms were transient with less than 2% visual injury 6 wk after transplanting. Due to increased weed control through harvest and the low injury potential, our results suggest that POST‐DIR applications of S‐metolachlor are the best fit for flue‐cured tobacco production when used in conjunction with recommended PTI herbicide programs.
The incidence of cardiovascular thrombotic complications after laparoscopic resection in colorectal cancer in Japanese hospitals: A large‐scale clinical study
Authors: Ichikawa Nobuki , Homma Shigenori , Funakoshi Tohru , Obuchi Keisuke , Ohshima Takahiro , Uemura Kazuhito , Kon Hirofumi , Ohno Yosuke , Yokota Ryoichi , Taketomi Akinobu ,   Hokkaido Colorectal Surgical Research Group Collaborative
Published: December 2021

AbstractAimThe aim of this retrospective study was to investigate the incidence of cardiovascular thrombotic complications after laparoscopic resection in colorectal cancer.MethodsThis study involved 2017 patients with stages 0‐III colorectal cancer who underwent laparoscopic surgery at 17 Japanese hospitals between January 2010 and December 2013. We assessed the incidence of postoperative cardiovascular thrombotic and haemorrhagic complications.ResultsLaparoscopic surgeries were performed in 1152 men and 865 women with 1405 colon and 612 rectal cancers, respectively. Overall, 3%, 38%, 17%, 8%, and 9% of patients had comorbidities of heart failure, high blood pressure, diabetes, history of stroke, and vascular disease, respectively. Antithrombotic agents were being consumed by 17% of patients. The types (and perioperative rest periods) of the antithrombotic agents were aspirin in 58% (18.6 days), clopidogrel in 19% (21.1 days), cilostazol in 13% (13.3 days), and warfarin potassium in 21% (14.6 days) of cases with antithrombotic agents. Surgical time and blood loss in the total cohort were 234 minutes and 56 mL. Four cases (0.2%) had cardiovascular thrombotic complications, including one severe cardiac infarction and one stroke with major sequelae (CHADS2 scores were 2 points in both cases). Hemorrhagic complications occurred in 19 cases (0.9%). In particular, the incidence of the major gastroduodenal haemorrhagic ulcer was higher in cases with antithrombotic agents than without them (0.05% vs 0%, P = .02).ConclusionThe incidence of cardiovascular thrombotic complications was rare, although severe cardiac infarction and stroke could occur even after minimally invasive surgery in colorectal cancer.
Katalytische asymmetrische Additionen von Enolsilanen an in situ erzeugte zyklische, aliphatischeN‐Acyliminiumionen
Authors: Grossmann Oleg , Maji Rajat , Aukland Miles H. , Lee Sunggi , List Benjamin 
Published: December 2021

AbstractStarke und sterisch umzäunte Imidodiphosphorimidatkatalysatoren (IDPi) ermöglichen hochenantioselektive Substitutionen von zyklischen, aliphatischen Hemiaminalethern mit Enolsilanen. 2‐Substituierte Pyrrolidine, Piperidine und Azepane werden mit hoher Enantioselektivität erhalten, und die Methode zeigt eine breite Toleranz gegenüber verschiedenen Enolsilanen. Mehrere Naturstoffe lassen sich mit dieser Methode gewinnen. Mechanistische Studien bestärken die Bildung des Ionenpaares zwischen nicht‐stabilisierten, zyklischenN‐(exo‐Acyl)iminiumionen, und dem sterisch umzäunten chiralen Gegenanion. Theoretische Studien legen Übergangszustände nahe, welche die beobachtete Enantioselektivität erklären.
Controlling the Complexity and Interconversion Mechanisms in Self‐Assembled [Fe2L3]4+ Helicates and [Fe4L6]8+ Cages
Authors: Siddique Rashid G. , Arachchige Kasun S. A. , AL‐Fayaad Hydar A. , Thoburn John D. , McMurtrie John C. , Clegg Jack K. 
Published: December 2021

AbstractSelf‐assembled coordination cages and metal–organic frameworks have relied extensively on symmetric ligands in their formation. Here we have prepared a relatively simple system employing an unsymmetric ligand that results in two distinct self‐assembled structures, a [Fe2L3]4+ helicate and a [Fe4L6]8+ cage composed of 10 interconverting diastereomers and their enantiomers. We show that the steric profile of the ligand controls the complexity, thermodynamics and kinetics of interconversion of the system.
Photoswitchable Epothilone‐Based Microtubule Stabilisers Allow GFP‐Imaging‐Compatible, Optical Control over the Microtubule Cytoskeleton**
Authors: Gao Li , Meiring Joyce C. M. , Heise Constanze , Rai Ankit , Müller‐Deku Adrian , Akhmanova Anna , Thorn‐Seshold Julia , Thorn‐Seshold Oliver 
Published: December 2021

AbstractOptical methods to modulate microtubule dynamics show promise for reaching the micron‐ and millisecond‐scale resolution needed to decrypt the roles of the cytoskeleton in biology. However, optical microtubule stabilisers are under‐developed. We introduce “STEpos” as GFP‐orthogonal, light‐responsive epothilone‐based microtubule stabilisers. They use a novel styrylthiazole photoswitch in a design to modulate hydrogen‐bonding and steric effects that control epothilone potency. STEpos photocontrol microtubule dynamics and cell division with micron‐ and second‐scale spatiotemporal precision. They substantially improve potency, solubility, and ease‐of‐use compared to previous optical microtubule stabilisers, and the structure‐photoswitching‐activity relationship insights in this work will guide future optimisations. The STEpo reagents can contribute greatly to high‐precision research in cytoskeleton biophysics, cargo transport, cell motility, cell division, development, and neuroscience.
Catalytic Asymmetric Additions of Enol Silanes to In Situ Generated Cyclic, AliphaticN‐Acyliminium Ions
Authors: Grossmann Oleg , Maji Rajat , Aukland Miles H. , Lee Sunggi , List Benjamin 
Published: December 2021

AbstractStrong and confined imidodiphosphorimidate (IDPi) catalysts enable highly enantioselective substitutions of cyclic, aliphatic hemiaminal ethers with enol silanes. 2‐Substituted pyrrolidines, piperidines, and azepanes are obtained with high enantioselectivities, and the method displays a broad tolerance of various enol silane nucleophiles. Several natural products can be accessed using this methodology. Mechanistic studies support the intermediacy of non‐stabilized, cyclicN‐(exo‐acyl)iminium ions, paired with the confined chiral counteranion. Computational studies suggest transition states that explain the observed enantioselectivity.