bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prosthetic valve endocarditis after transcatheter aortic valve replacement in low‐risk patients
Authors: Medranda Giorgio A. , Rogers Toby , Ali Syed W. , Zhang Cheng , Shea Corey , Sciandra Kathryn A. , Case Brian C. , Forrestal Brian J. , Sutton Joseph A. , McFadden Eugene P. , Malla Prerna , Gordon Paul , Ehsan Afshin , Wilson Sean R. , Levitt Robert , Parikh Puja , Bilfinger Thomas , Torguson Rebecca , Asch Federico M. , Weissman Gaby , Ben‐Dor Itsik , Shults Christian C. , Garcia‐Garcia Hector M. , Satler Lowell F. , Waksman Ron 
Published: September 2021

AbstractObjectivesWe sought to report details of the incidence, organisms, clinical course, and outcomes of prosthetic valve endocarditis (PVE) after transcatheter aortic valve replacement (TAVR) in low‐risk patients.BackgroundPVE remains a rare but devastating complication of aortic valve replacement. Data regarding PVE after TAVR in low‐risk patients are lacking.MethodsWe performed a detailed review of all patients in the low‐risk TAVR trials who underwent TAVR from 2016 to 2020 and were adjudicated to have definitive PVE by the independent Clinical Events Committee.ResultsWe analyzed 396 low‐risk patients who underwent TAVR (including 72 with bicuspid valves). PVE occurred in 11 patients at a median 379 days (210, 528) from TAVR. The incidence within the first 30 days was 0%; days 31–365, 1.5%; and after day 365, 2.8%. The most common organism identified was Streptococcus (n = 4/11). Early PVE (≤ 365 days) occurred in five patients, of whom three demonstrated evidence of embolic stroke and two underwent surgical aortic valve re‐intervention. Late PVE (> 365 days) occurred in six patients, of whom thee demonstrated evidence of embolic stroke and only one underwent surgical aortic valve re‐intervention. Of the six patients with evidence of embolic stroke, two died, two were discharged to rehabilitation, and two were discharged home with home care.ConclusionsPVE was infrequent following TAVR in low‐risk patients but was associated with substantial morbidity and mortality. Embolic stroke complicated the majority of PVE cases, contributing to worse outcomes in these patients. Efforts must be undertaken to minimize PVE in TAVR.
LBR‐GWO: Layered based routing approach using grey wolf optimization algorithm in wireless sensor networks
Authors: Dwivedi Bhanu , Patro Bachu Dushmanta Kumar , Srivastava Vivek , Jadon Shimpi Singh 
Published: September 2021

SummaryThe sensors deployed inside a wireless sensor network (WSN) have limited energy sources, significantly impacting the network throughput. This article's research objective is to increase network lifetime by developing an energy‐efficient layered‐based routing algorithm for WSNs using the grey wolf optimization (LBR‐GWO) algorithm. In this, the grey wolf's leadership hierarchy has followed, which improves the network's energy capability. The entire region of the deployed nodes divides into four layers. In these nodes, layer one is chosen as cluster heads. If more than two nodes are present in layer one, then the cluster head is selected based on the game theory model; otherwise, the decision is made based on the node's residual energy. While the existing algorithm has several complex control parameter points, the current algorithm has fewer complex parameters. Therefore, in comparison to other algorithms, this algorithm is easy to apply in cluster‐based sensor networks. Simulation findings prove the LBR‐GWO algorithm supremacy for balancing energy consumption across the nodes and improving the network's lifetime compared to the LEACH, HEED, and PSO protocols.
Isobutane Transformation to Aromatics on Zn‐Modified Zeolites: Intermediates and the Effect of Zn2+and ZnO Species on the Reaction Occurrence Revealed by13C MAS NMR
Authors: Gabrienko Anton A. , Lashchinskaya Zoya N. , Arzumanov Sergei S. , Toktarev Alexander V. , Freude Dieter , Haase Jürgen , Stepanov Alexander G. 
Published: September 2021

AbstractTo clarify the effects of different Zn species, zeolite topology and acidity (quantity of Brønsted acid sites, BAS) on alkane aromatization, isobutane transformation on Zn2+/H‐ZSM‐5, Zn2+/H‐BEA, and ZnO/H‐BEA zeolites has been monitored with13C MAS NMR. The alkane transformation has been established to occur by aromatization and hydrogenolysis pathways. Zn2+species is more efficient for the aromatization reaction because aromatic products are formed at lower temperatures on Zn2+/H‐BEA and Zn2+/H‐ZSM‐5 than on ZnO/H‐BEA. The larger quantity of BAS in ZnO/H‐BEA seems to provide a higher degree of the hydrogenolysis pathway on this catalyst. The mechanism of the alkane aromatization is similar for the zeolites of different topology and containing different Zn species, with the main reaction steps being the following: (i) isobutane dehydrogenation to isobutene via isobutylzinc; (ii) isobutene stabilization as a π‐complex on Zn sites; (iii) isobutene oligomerization via the alkene insertion into Zn−C bond of methyl‐σ‐allylzinc formed from the π‐complex; (iv) oligomer dehydrogenation with intermediate formation of polyene carbanionic structures; (v) aromatics formation via further polyene dehydrogenation, protonation, cyclization, deprotonation steps with BAS involvement.
Blood small extracellular vesicles derived miRNAs to differentiate pancreatic ductal adenocarcinoma from chronic pancreatitis
Authors: Guo Shiwei , Qin Hao , Liu Ke , Wang Huan , Bai Sijia , Liu Shiyi , Shao Zhuo , Zhang Yanan , Song Bin , Xu Xiaoya , Shen Jing , Zeng Peng , Shi Xiaohan , Chen Hao , Gao Suizhi , Xu Jiajia , Pan Yaqi , Xiong Lei , Li Fugen , Zhang Dadong , Jiao Xiaodong , Jin Gang 
Published: September 2021

AbstractBackgroundThe differential diagnosis of pancreatic ductal adenocarcinoma (PDAC) from chronic pancreatitis (CP) is clinically challenging due to a lack of minimally invasive diagnosis methods. MicroRNAs (miRNAs) derived from small extracellular vesicles (EVs) in the blood have been reported as a promising diagnosis biomarker for various types of cancer. However, blood small EV miRNA signatures and their diagnostic value to differentiate between PDAC and CP remain to be determined.MethodsIn this study, 107 patients with PDAC or CP were recruited, and 90 patients were finally enrolled for a training cohort (n = 48) and test cohort (n = 42). Small RNA sequencing was used to assess the expression of blood small EV miRNAs in these patients.ResultsThe linear model from the differentially expressed blood small EV miR‐95‐3p divided by miR‐26b‐5p showed an average sensitivity of 84.1% and an average specificity of 96.6% to identify PDAC from CP in the training cohort and the test cohort, respectively. When the model was combined with serum carbohydrate antigen 19‐9 (CA19‐9), the average sensitivity increased to 96.5%, and the average specificity remained at 96.4% of both cohorts, which demonstrated the best performance of all the published biomarkers for distinguishing between PDAC and CP. The causal analysis performed using the Bayesian network demonstrated that miR‐95‐3p was associated with a “consequence” of “cancer” and miR‐26b‐5p as a “cause” of “pancreatitis.” A subgroup analysis revealed that blood small EV miR‐335‐5p/miR‐340‐5p could predict metastases in both cohorts and was associated with an overall survival (p = 0.020).ConclusionsThis study indicated that blood small EV miR‐95‐3p/miR‐26b‐5p and its combination with serum levels of CA19‐9 could separate PDAC from CP, and miR‐335‐5p/miR‐340‐5p was identified to associate with PDAC metastasis and poor prognosis. These results suggested the potentiality of blood small EV miRNAs as differential diagnosis and metastases biomarkers of PDAC.
Environmental associations of cownose ray (Rhinoptera bonasus) seasonal presence along the U.S. Atlantic Coast
Authors: Bangley Charles W. , Edwards Michelle L. , Mueller Claire , Fisher Robert A. , Aguilar Robert , Heggie Keira , Richie Kimberly , Ahr Bonnie J. , Ogburn Matthew B. 
Published: September 2021

AbstractIdentifying the mechanistic drivers of migration can be crucial in shaping conservation and management policies. The cownose ray (Rhinoptera bonasus) is a relatively poorly understood elasmobranch species that occurs along the U.S. Atlantic coast and undergoes large‐scale seasonal migrations. To better understand the drivers and timing of cownose ray seasonal migration in order to inform potential management measures, we analyzed telemetry detections of 51 mature cownose rays (38 female, 13 male) tagged with acoustic transmitters in the Maryland and Virginia portions of Chesapeake Bay. Detections within their summer habitat in Chesapeake Bay and winter habitat in the vicinity of Cape Canaveral, Florida, were matched with publicly available sea surface temperature (SST) data recorded by data buoys near the areas of tag detections and with local photoperiod and day of year. These variables were used in boosted regression tree models of ray presence (all rays combined, females only, and males only) in each seasonal habitat. Models were developed for presence during the entire summer and winter season, and for the time periods of arrival and departure from both summer and winter habitats. Seasonal presence in both summer and winter habitats was associated with distinct temperature, photoperiod, and date ranges, with temperature as the most influential variable in seasonal models. In models of arrival and departure periods, southward migration (departure from Chesapeake Bay and arrival off Cape Canaveral) was strongly associated with SST for all rays and arrival in the Chesapeake Bay region after northward migration was most strongly associated with day of year. The most influential variable during the period of northward departure from Cape Canaveral differed between males (day of year) and females (SST). This suggests that mature female northward migration may be driven by temperature while male northward migration may be driven by endogenous cues. These findings provide detailed information on the timing of cownose ray arrival at, presence in, and departure from seasonal habitats and provide potential justification for including the species in cross‐taxa comparative studies on migratory behavior.
H2O2‐Induced Oxidative Dissolution of UO2 in Saline Solutions
Authors: El Jamal Ghada , Li Junyi , Jonsson Mats 
Published: September 2021

AbstractH2O2 is one of the oxidants responsible for driving the process of radiation‐induced dissolution of spent nuclear fuel in geological repositories for spent nuclear fuel. As the groundwater composition will vary depending on geographical location as well as on the age of the repository (in relation to glacial cycles, etc.), it is important to elucidate the impact of different groundwater constituents. While several studies have addressed the impact of HCO3− and halide ions on the radiation chemistry of water in general and radiation‐induced oxidative dissolution of spent nuclear fuel in particular, very few studies have addressed the impact of halide ions on the mechanism of the reaction between H2O2 and UO2. In this work, the impact of Cl−, Br− and ClO4− on the mechanism and kinetics of H2O2‐induced oxidative dissolution of UO2‐powder in aqueous suspensions with and without added HCO3− has been studied experimentally. The experiments reveal both ionic strength effects and specific ion effects on the kinetics of the reactions involved. These are discussed in connection to the results.
One Pot Synthesis of Dithiolane Dendron Functionalized Gold Nanoparticles
Authors: Perton Francis , Palluel Marlène , Kiefer Céline , Freis Barbara , Mertz Damien , Begin‐Colin Sylvie 
Published: September 2021

AbstractThe theranostic properties of gold nanoparticles (GNPs) depend on their size and shape but also on their challenging coating. Indeed, the GNPs coating step is not easy to perform and often affects their colloidal stability and aggregation state. We investigated the one‐pot synthesis of GNPs with a size higher than 10 nm and coated with dendrons by testing different synthesis processes. With the Brust‐Schriffin method, the very fast reduction of HAuCl4 affects the growth step. The decrease of the reduction kinetics by tuning the reaction temperature and the NaBH4 injection speed led to spherical GNPs with a size ∼30 nm. The seed mediated method conducted always to the presence of very small nuclei beside bigger GNPs despite a Ostwald ripening treatment. Finally, the modification of the gold precursor by tuning the pH of gold salt suspensions was shown very promising to better control the nucleation and growth steps and obtain dendronized GNPs in a one‐pot step (ratio 100 : 1 and pH=2.3).
The Effect of Harvesting Time on Olive Fruits and Oils Quality Parameters of Tortiglione and Dritta Olive Cultivars
Authors: Flamminii Federica , Marone Elettra , Neri Lilia , Pollastri Luciano , Cichelli Angelo , Di Mattia Carla Daniela 
Published: September 2021

AbstractDespite the fact that Italy holds the most important olives heritage in the world, with about 800 cultivars, most of them are still underestimated, in particular those from Abruzzo, a region located in the center of the peninsula. The aim of this work is to study the changes in quality parameters of olive fruits and related oils of two autochthonous Abruzzo olive cultivars, Tortiglione and Dritta during ripening (from September to November 2017). Both cultivar and ripening time affect the chemical parameters of olive fruits. Results highlight an increasing trend of the oil content with final values, based on fresh matter, of 38.7 ± 0.3% and 38.1 ± 0.9% for Tortiglione and Dritta, respectively. Olive oils chemical composition is also affected by ripening time and cultivar, with Tortiglione oils resulting generally richer than Dritta oils; on the first sampling time (30th of October) values for total phenolic content, antioxidant activity, and chlorophylls are 803.8 ± 68.2 mg gallic acid equivalent kg−1, 2.7 ± 0.5 mmol trolox equivalent kg−1, and 30.8 ± 1.6 mg pheophytin a kg−1, respectively. Tocopherols seem to be more affected by ripening time than by cultivar, in particular for Dritta.Practical Application: The results on Abruzzo minor olive cultivars indicate that olive fruits and olive oil composition are strongly influenced by both cultivar and ripening time, giving rational indications about the optimal cultivar specific harvesting time and opening interesting opportunities for olive oil producers in a perspective of sustainable production to obtain high quality fruits and oils. The research provides detailed information about Tortiglione and Dritta olive cultivar, useful in the global context of revaluation of Italian minor olive varieties.
Lipidomics Screening of Polyunsaturated Phospholipid Molecular Species in Crab (Portunus trituberculatus) Muscular Tissue: A Nontarget Approach by HILIC‐MS
Authors: Zhang Yunfeng , Zhang Min , Dong Linpei , Chang Jing , Wang Haixing , Shen Qing 
Published: September 2021

AbstractThe phospholipid molecular species (PMS) in the muscular tissue of the swimming crab (Portunus trituberculatus) are extracted and quantified using aminopropyl coated silica‐based solid‐phase extraction (SPE) and hydrophilic interaction chromatography‐mass spectrometry (HILIC‐MS), respectively. Once the lipidomics profile is acquired, the contents of PMS are semiquantitatively determined using linear regression models. It is found that in swimming crab, phosphatidylcholine (PC, 14.30 mg g−1) is the most abundant phospholipid class, followed by phosphatidylethanolamine (PE, 8.20 mg g−1), phosphatidylinositol (PI, 1.60 mg g−1), and phosphatidylserine (PS, 9.83 mg g−1). The nutritional eicosapentaenoic acid and/or docosahexaenoic acid structured phospholipids exist in swimming crabs, such as PC 18:0/20:5, PE 18:1/20:5 and 16:0/22:6, PI 18:0/20:5. Besides, plasmalogens are detected, such as PC o‐16:0/22:6 and PE o‐18:0/20:5. Finally, this method is validated to be efficient and accurate in terms of linearity (correlation coefficients, R2 0.9976 to 0.9993), sensitivity (limit of detection, LOD, 0.22–0.33 µg mL−1), precision (relative standard deviation, RSDintra‐day ≤ 4.11%), and recovery (78% to 85%, RSD ≤ 5.79%). In conclusion, swimming crab is rich in health‐beneficial phospholipids, such as eicosapentaenoic acid and/or docosahexaenoic acid structured phospholipids and plasmalogens, and the muscular tissue is proved to be of high nutritional value.Practical Applications: The study introduces a potential method for the lipidomics screening of polyunsaturated phospholipid molecular species in food.
The effects of wind‐generated currents on velocity asymmetry in tidal basins with varying geometries
Authors: de Ruiter Peter J. , Mullarney Julia C. , Bryan Karin R. 
Published: September 2021

AbstractGeomorphologic characteristics of tidal basins have been shown to control tidal asymmetry and associated sediment transport potential in coastal regions. In this study, we examine how winds modulate horizontal velocity asymmetry patterns in shallow tidal basins. Numerical modelling experiments for a series of idealized basins in which planform shape and bathymetry were varied, reveal that an increase in wind speed promotes more extreme horizontal velocity asymmetry (larger velocity asymmetry values) without substantially altering the overall spatial pattern of velocity asymmetry throughout the domains. The wind forcing primarily influences mean and peak flow velocities, with a limited effect on tidal harmonics. Changes to the velocity asymmetry patterns are most evident for wind speeds of 6 m/s and greater, and for wind directions parallel to the main axes of the basins’ tidal channels. However, the velocity asymmetry is strongly depth‐dependent. Shallow intertidal basin regions are characterized by a downwind‐directed increase in velocity asymmetry, whereas deeper subtidal channels display asymmetry changes in the opposite direction. Additionally, the timing and duration of a wind event are found to influence the velocity asymmetry patterns. Wind events coinciding with flooding tides result in the most noteworthy differences between the relative size of the peak flood‐ and ebb‐directed currents inside the shallow basins, for wind event durations of both 3 and 6 h.
Comparative Evaluation of the Polar Organic Chemical Integrative Sampler in Two Types of Validation Systems Simulating Peak Concentration Events
Authors: Noro Kazushi , Vermeirssen Etiënne L.M. , Banno Arisa , Ono Junko , Yabuki Yoshinori 
Published: September 2021

Abstract
Polar organic chemical integrative sampler (POCIS) devices have been suggested for measuring time-weighted averages (TWAs) of contaminant concentrations resulting from chemical leak accidents in aquatic environments. However, the response of the POCIS device in the emergency condition in natural water remains unclear. The response of the POCIS device to contaminant fluctuation was investigated using a chamber test with tap water and a channel test with natural water. The fluctuation in the chamber and the channel simulated the condition of river water under a chemical leak scenario (maximum concentration: 1–10 μg L–1, half-life: 1 day). The target chemicals were neonicotinoid pesticides (dinotefuran, clothianidin, thiamethoxam, imidacloprid, acetamiprid, and thiacloprid) and bisphenol A. The ratio of the POCIS measured value to the TWA values of grab samplings (POCIS/TWA) for the channel test (temperature: 15 °C, flow velocity: 15 cm s–1) ranged from 61% (clothianidin) to 133% (thiacloprid). The results indicated that the POCIS device could be effectively used as a monitoring device in an aquatic environment under the chemical leak scenario over a time period of more than14 days. In addition, the POCIS/TWA ratios obtained from the chamber test and the channel test were in the range of 50–150%. Thus, the chamber test could be used to evaluate the POCIS device at a low cost. Environ Toxicol Chem 2021;40:3010–3018. © 2021 SETAC
Investigation and development of the multicycle of CO2 mineralization with wastewater under standard conditions
Authors: Thamsiriprideeporn Chanakarn , Suekane Tetsuya 
Published: September 2021

AbstractCO2 mineralization is promising for carbon capture and storage (CCS). The multiple reuses of monoethanolamine (MEA) as absorbents for CO2 absorption and carbonate generation with minerals in wastewater between 20 and 25°C at atmospheric pressure (standard conditions) efficiently reduce both cost and energy penalties for industrial application. In this study, the multicycle of CO2 mineralization was performed in three steps: absorption, precipitation, and regeneration. We found that 5 wt.% MEA solution has great potential in terms of 24.26 moles of CO2 absorbing capacity per mole of MEA and 0.1535 moles of carbonate conversion per mole of MEA within less than 1.8 h operation time, which the optimal repetitions was 5‐cycle before MEA complete degradation. To reduce absorption time, we studied packing bed of 2‐, 4‐, 6‐, and 8 mm diameter nonreactive spherical glass beads were operated in the columns with 5 wt.% MEA solutions. The maximum benefit was obtained from the 8‐mm‐packing diameter, which fully accorded 28.85 and 0.1687 moles of CO2 and carbonate, respectively, per mole of 5 wt.% MEA within 44 min, providing the highest conversion in a relatively short time. The efficiency of regenerated MEA absorbent was reduced from 20 to 10% due to degradation. Raman spectroscopy, X‐ray diffractometry, and scanning electron microscopy were used to analyze the composition and crystal structure of carbonates. The main product of carbonates was calcite, which was mixed with complex salts, such as aragonite, magnesite, and dolomite. © 2021 Society of Chemical Industry and John Wiley & Sons, Ltd.
Time‐driven activity‐based costing as a strategy to increase efficiency: An analyses of interventional coronary procedures
Authors: da Silva Etges Ana Paula Beck , Cruz Luciane Nascimento , Schlatter Rosane , Neyeloff Jeruza , Cardoso Ricardo Bertoglio , Kopittke Luciane , Nunes Altacilio Aparecido , Neto José Alburquerque , Nogueira José Luiz , de Assis Renata Melo , Tobias Joilma Silva Prazeres , Marin‐Neto José Antonio , Moreira Leila Beltrami , Polanczyk Carisi Anne 
Published: September 2021

AbstractMonitoring the costs is one of the key components underlying value‐based health care. This study aimed to evaluate the cost‐saving opportunities of interventional coronary procedures (ICPs). Data from 90 patients submitted to elective ICP were evaluated in five Brazilian hospitals. Time‐driven activity‐based costing, that guides the cost estimates using the time consumed and the capacity cost rates per resource as the data input, was used to assess costs and the time spent over the care pathway. Descriptive cost analyses were followed by a labour cost‐saving estimate potentially achieved by the redesign of the ICP pathway. The mean cost per patient varied from $807 to $2639. The length of the procedure phase per patient was similar among the hospitals, while the post‐procedure phase presented the highest variation in length. The highest direct cost saving opportunities are concentrated in the procedure phase. By comparing the benchmark service with the most expensive one, it was estimated that redesigning physician practices could decrease 51% of the procedure cost. This application is pioneered in Brazil and demonstrates how detailed cost information can contribute to driving health care management to value by identifying cost‐saving opportunities.