bluuebunny/crossref_metadata_2025_split huggingface dataset:
Acceptability of psychologically-based pain management and online delivery for people living with HIV and chronic neuropathic pain: a qualitative study
Authors: Scott Whitney , Badenoch James , Garcia Calderon Mendoza del Solar Maite , Brown Darren A. , Kemp Harriet , McCracken Lance M. , C de C Williams Amanda , Rice Andrew S. C. 
Published: February 2021

Abstract

Objectives
Chronic neuropathic pain is common in people living with HIV. Psychological treatments can improve quality of life for people with chronic pain in general, and online delivery can increase access to these treatments. However, the acceptability of psychological treatment and online delivery have not been investigated in-depth in people living with HIV and chronic neuropathic pain. Therefore, a qualitative study was undertaken to explore views about a psychological treatment for pain management in this population and to investigate the acceptability of online treatment delivery.

Methods
Qualitative interviews were conducted and analysed using inductive thematic analysis, adopting a critical realist perspective. Twenty-six people living with HIV and chronic neuropathic pain completed semi-structured interviews. Their views about a psychological treatment for pain management and online delivery were explored in-depth.

Results
Three themes and 12 subthemes were identified. Theme one represents a desire for a broader approach to pain management, including not wanting to take more pills and having multidimensional goals that were not just focussed on pain relief. Theme two includes barriers to online psychologically-based pain management, including concerns about using the Internet and confidentiality. Theme three describes treatment facilitators, including accessibility, therapist support, social connection, and experiencing success.

Conclusions
A psychological treatment for chronic neuropathic pain management appears acceptable for people living with HIV. Therapist-supported online delivery of cognitive-behavioural pain management may be acceptable for people living with HIV given appropriate development of the treatment to address identified barriers to engagement. These data can inform developments to enhance engagement in online psychologically-informed pain management in people living with HIV and more broadly in remote delivery of psychological treatments.
Aufstellung einer Messunsicherheitsbilanz für ein primäres Messverfahren zur Bestimmung der elektrolytischen Leitfähigkeit
Authors: Breuel Ulrich , Werner Barbara , Schiering Nadine , Zeißler Andreas 
Published: February 2021

Zusammenfassung
Die elektrolytische Leitfähigkeit ist eine wichtige Messgröße zur Kontrolle und Überwachung von Prozessen in wässrigen Medien, die in unterschiedlichen Bereichen der Industrie von Bedeutung sind. In der metrologischen Hierarchie sind die primären Messverfahren allen anderen übergeordnet, d. h. ihnen nachgeordnet sind sekundäre Messverfahren (z. B. mit Standardmesszellen) sowie Messungen mit kommerziellen Leitfähigkeitsmessgeräten mit 2- und 4-Polmesszellen.
Die ZMK & ANALYTIK GmbH entwickelte eine Primärmesseinrichtung für die elektrolytische Leitfähigkeit. Die Temperierung wurde durch Durchführung der Messungen in einem Flüssigkeitsbad realisiert.
Der folgende Artikel beinhaltet die Aufstellung der Messunsicherheitsbilanz für das primäre Messverfahren. Die kombinierte Messunsicherheit setzt sich aus mehreren Beiträgen zusammen. Als wichtige Beiträge wurden die Widerstandsmessung, die Messung der Temperatur sowie die Verschiebung der Messelektroden um einen definierten Verschiebeweg in der Messunsicherheit berücksichtigt, die sich wiederum aus Einzelbeiträgen zusammensetzen. Die einzelnen Messunsicherheitsbeiträge der elektrischen Messungen (Widerstände), der Messungen der Temperatur, den dimensionellen Messungen sowie weitere Beiträge werden detailliert dargestellt. Die Korrelation einzelner Beiträge untereinander wird berücksichtigt.
Anti-inflammatory genes in PBMCs post-spontaneous intracerebral hemorrhage
Authors: Nguyen Doan , Tran Vi , Shirazian Alireza , Velasco-Gonzalez Cruz , Iwuchukwu Ifeanyi 
Published: February 2021

Abstract

Background
Neuroinflammation is important in the pathophysiology of spontaneous intracerebral hemorrhage (ICH) and peripheral inflammatory cells play a role in the clinical evolution and outcome.

Methodology
Blood samples from ICH patients (n = 20) were collected at admission for 5 consecutive days for peripheral blood mononuclear cells (PBMCs). Frozen PBMCs were used for real-time PCR using Taqman probes (NFKB1, SOD1, PPARG, IL10, NFE2L2, and REL) and normalized to GAPDH. Data on hospital length of stay and modified Rankin score (MRS) were collected with 90-day MRS ≤ 3 as favorable outcome. Statistical analysis of clinical characteristics to temporal gene expression from early to delayed timepoints was compared for MRS groups (favorable vs unfavorable) and hematoma volume.

Principle findings and results
IL10, SOD1, and REL expression were significantly higher at delayed timepoints in PBMCs of ICH patients with favorable outcome. PPARG and REL increased between timepoints in patients with favorable outcome. NFKB1 expression was not sustained, but significantly decreased from higher levels at early onset in patients with unfavorable outcome. IL10 expression showed a negative correlation in patients with high hematoma volume (>30 mL).

Conclusions and significance
Anti-inflammatory, pro-survival regulators were highly expressed at delayed time points in ICH patients with a favorable outcome, and IL10 expression showed a negative correlation to high hematoma volume.
Calumenin contributes to epithelial-mesenchymal transition and predicts poor survival in glioma
Authors: Yang Ying , Wang Jin , Xu Shihai , Shi Fei , Shan Aijun 
Published: February 2021

AbstractBackgroundCalumenin (CALU) has been reported to be associated with invasiveness and metastasis in some malignancies. However, in glioma, the role of CALU remains unclear.MethodsClinical and transcriptome data of 998 glioma patients, including 301 from CGGA and 697 from TCGA dataset, were included. R language was used to perform statistical analyses.ResultsCALU expression was significantly upregulated in more malignant gliomas, including higher grade, IDH wildtype, mesenchymal, and classical subtype. Gene Ontology analysis revealed that CALU-correlated genes were mainly enriched in cell/biological adhesion, response to wounding, and extracellular matrix/structure organization, all of which were strongly correlated with the epithelial-mesenchymal transition (EMT) phenotype. GSEA further validated the profound involvement of CALU in EMT. Subsequent GSVA suggested that CALU was particularly correlated with three EMT signaling pathways, including TGFβ, PI3K/AKT, and hypoxia pathway. Furthermore, CALU played synergistically with EMT key markers, includingN-cadherin, vimentin, snail, slug, and TWIST1. Survival and Cox regression analysis showed that higher CALU predicted worse survival, and the prognostic value was independent of WHO grade and age.ConclusionsCALU was correlated with more malignant phenotypes in glioma. Moreover, CALU seemed to serve as a pro-EMT molecular target and could contribute to predict prognosis independently in glioma.
Thomas Linke: Rudolf Otto: Parallelen und Wertunterschiede im Christentum und Buddhatum
Authors: Linke Thomas 
Published: February 2021

Abstract
This is a new (and for the first time complete) edition of a speech about Buddhism by Rudolf Otto from 1913. This speech is his first academic reflexion of his journey around the world and his most detailed explanation of his view on this religion. In the first part of his speech Otto compares Buddhism with Christianity and finds a lot of parallels. In the second part he defines differences between these two religions and proclaims – from a Christian perspective – Christianity as more valuable than Buddhism. The preface puts the speech into its context: Otto’s relationship to and his knowledge of Buddhism (1), the history of publication of this speech (2), Otto’s specific view on Buddhism in comparison to his contemporaries (3), the meaning of this speech in his œuvre (4) and explanations about the edition (5). The editor has the opinion, that this speech is an important transition from Ottos philosophy of religion to his main work The Idea of the Holy. It further is a good example of what Otto means when speaking about the comparison of religions.
Kinetics, equilibrium and thermodynamics of dyes adsorption onto modified chitosan: a review
Authors: Kausar Abida , Naeem Kashaf , Iqbal Munawar , Nazli Zill-i-Huma , Bhatti Haq N. , Ashraf Aisha , Nazir Arif , Kusuma Heri S. , Khan Muhammad I. 
Published: February 2021

Abstract
In view of promising sorption capacity, stability, biodegradability, cost-effectiveness, environmental friendly nature, regeneration and recycling ability, the chitosan (CS) based adsorbents are highly efficient for the sequestration of dyes. Since CS offers variable chemical structures and CS have been modified by incorporating different moieties. The CS composites with unique properties have been employed successfully for dye adsorption with reasonably high adsorption capacity versus other similar adsorbents. Modifications of CS were promising for the preparation of composites that are extensively studied for their adsorption capacities for various dyes. This review highlights the CS and its modification and their applications for the adsorption of dyes. The removal capacities of CS-based adsorbents, equilibrium modeling, kinetics studies and the thermodynamic characteristics are reported. Moreover, the FTIR, BET, SEM, TGA and XRD were employed for the characterization of CS modified adsorbents are also discussed. Results revealed that the modified CS is highly efficient and can be employed for the sequestration of dyes from effluents.
Sex differences in the prevalence of obesity in 800,000 Chinese adults with type 2 diabetes
Authors: Lv Fang , Cai Xiaoling , Lin Chu , Hong Tianpei , Zhang Xiaomei , Wang Zhufeng , Xing Huifang , Zong Guizhi , Lu Juming , Guo Xiaohui , Wu Jing , Gao Leili , Zhou Xianghai , Han Xueyao , Ji Linong 
Published: February 2021

Aims
To estimate the sex differences in the prevalence of overweight and obesity aged 20–89 in Chinese patients with type 2 diabetes (T2D).

Methods
811,264 patients with T2D from six hospital-based, cross-sectional studies, and 46,053 subjects from the general population were included in our analysis. Prevalence of underweight, overweight, obesity were calculated in each sex.

Results
In patients with T2D, the standardized prevalence of underweight (BMI <18.5 kg/m2), overweight (24 kg/m2 ≤ BMI < 28 kg/m2), and general obesity (BMI ≥28 kg/m2) were 2.2%, 43.2%, and 11.6%, respectively. Similar trend patterns of the prevalence of underweight and overweight were observed in general and T2D population, in males and females with T2D (all P for trend <0.01). In patients with T2D, patients at a younger age and older age were more likely to be underweight. The prevalence of overweight increased first, then stabilized or decreased with age. However, different trend patterns of the prevalence of obesity in males and females were found. In males, the prevalence of obesity decreased first, and then stabilized after 60 years of age. In females, the prevalence of obesity decreased first, then increased after 50 years of age. In the general population, the prevalence of obesity increased with age in females, while, the trend of prevalence of obesity with age in males was not obvious.

Conclusion
Different trends in the prevalence of obesity with age in different sex were found in Chinese patients with T2D.
Androgens impair β-cell function in a mouse model of polycystic ovary syndrome by activating endoplasmic reticulum stress
Authors: Zhu Bo , Chen Yumei , Xu Fang , Shen Xiaolu , Chen Xuanyu , Lv Jieqiang , Zhang Songying 
Published: February 2021

Background
Androgens excess results in endoplasmic reticulum (ER) stress, which is an important cause of β cells dysfunction. Here, we investigated the molecular regulation of androgens excess, ER stress, and β-cell function in polycystic ovary syndrome (PCOS).

Methods
PCOS mouse model was established by injection of DHEA. Primary cultured mouse islets were used to detect testosterone (TE)-induced ER stress. The response of ER stress, apoptosis, and hyperinsulinemia were analyzed in INS-1 cells with or without TE exposure. Androgen receptor (AR) antagonist and ER stress inhibitor treatment was performed to evaluate the role of TE in ER stress and proinsulin secretion of PCOS mice.

Results
PCOS mice had higher ER stress in islets. TE exposure induced ER stress and apoptosis significantly through sustaining insulin overexpression in β cells, which in turn impaired proinsulin maturation and secretion. Blocking this process could significantly relieve ER stress and apoptosis and improve insulin homeostasis.

Conclusion
ER stress activated by androgens excess in PCOS contributes to β cell dysfunction and hyperinsulinemia.
Production of bio-oil and bio-char from pyrolysis of sawdust wood waste (SWW)
Authors: Guida M.Y. , Lanaya S.E. , Laghchioua F.E. , Rbihi Z. , Hannioui A. 
Published: February 2021

AbstractThis study deals with fast pyrolysis of sawdust wood waste (SWW) at the range of temperature 300–700 °C in a stainless steel tubular reactor. The aim was to experimentally investigate how the temperature, the particle size, the nitrogen flow rate (N2) and the heating rate affect bio-oil, bio-char and gaseous products. These parameters were varied in the ranges of 5–20 °C/min, below 0.1–1.5 mm and 20–200 mL min−1, respectively. It was concluded that both the temperature and heating rate have a significant effect on both yield of bio-oil and bio-char resulting from pyrolysis of SWW. The liquid products obtained at various pyrolysis temperatures were subjected into column chromatography after removal of asphaltenes (hexane insoluble). Obtained bio-oils (maltenes or hexane soluble) were classified as aliphatic, aromatic and polar sub-fractions. The maximum of bio-oil yield of 39.5 wt% was obtained at a pyrolysis temperature of 500 °C, particle size between 0.5 and 1 mm, nitrogen flow rate (N2) of 100 mL min−1 and heating rate of 5 °C/min. Liquid product (bio-oil) obtained under the most suitable and optimal condition was characterized by elemental analysis, Nuclear magnetic resonance spectroscopy (1H NMR and 13C NMR), Fourier transformed infrared spectroscopy (FT-IR). The analysis of liquid showed that bio-oil from SWW could be a potential source of renewable fuel production and value added chemical. The yield of char generally decreases with increasing the temperature, the char yield passes from 54.61 to 29.47 wt% at the heating rate of 5 °C/min and from 50.01 to 24.5 wt% at the heating rate of 20 °C/min at the same range of temperature (300–700 °C). Solid products (bio-char) obtained in the presence of nitrogen (N2) contain a very important percentage of carbon and high heating values (HHVs).
An ethnobotanical survey of spontaneous plants used in traditional medicine in the region of Aures, Algeria
Authors: Baziz Karim , Maougal Rim Tinhinene , Amroune Abdelkader 
Published: February 2021

This study carried out in the Aures region (Algeria) between September 2018 and March 2019, allowed us to identify spontaneous plants used in the region and gather all the information concerning the therapeutic practices of the local population. Based on a series of ethnobotanical surveys, we have identified 112 medicinal species belonging to 49 families, of which Asteraceae, Poaceae, Lamiaceae, Fabaceae, Amaranthaceae and Cupressaceae are the most represented. The leaves were the most used plant parts (28.86%), and the decoction (37.68%) represents the most frequently used mode of preparation. In addition, the remedies were prepared essentially from single species (81.15%) and were used mainly in the treatment of digestive disorders (23.99%). The study has also shown that women, married people, the elderly and illiterates people had the better knowledge of the use of medicinal plants.
These results indicate that local population has a fairly deep empirical and traditional knowledge of phytotherapy. However, this knowledge is endangered mainly because of the mode of transmission which is based on oral tradition and an urgent transcription is needed to avoid the loss of this heritage.
Development of Distance Technologies in Physical Education of Students: Opportunities and Challenges
Authors: Koryahin Viktor , Blavt Oksana 
Published: February 2021

Purpose. To identify the state of teaching “Physical Education” by means of distance technologies at the university. Materials and methods. The study involved 3,726 first-year students of the Lviv Polytechnic National University of all educational-and-scientific institutes. The organization of the study was aimed at studying the opinion of students on various issues regarding the quality of distance education in physical education. At the empirical level of the study, a questionnaire was used. Results. The study analyzed the state of physical education at the university by means of distance learning. According to the results of the survey, it was found that the vast majority of surveyed students (81.3%) believe that physical education classes by means of distance learning are necessary in the conditions of introduction of quarantine safety measures. 51.6% of students noted that methodical skills gained during the classes significantly helped them in organizing independent physical training sessions during the suspension of educational activities in auditoriums. 71% support the possibility of physical education classes by means of distance technologies in order to counteract the forced restriction of motor activity. Conclusions. Ensuring the effectiveness of physical education of students in the position of quarantine measures requires new approaches and methods of interaction with students, adequate choice of goals and objectives, organizational forms, methods and means of physical education maintain the proper level of their motor activity and prevent social maladaptation. From the study, we can conclude that physical education by means of distance technologies is in a state of development, but not at such a rapid pace. Instead, on the basis of the study summarizes that the use of distance learning means in physical education of students ensures the formation of values of a healthy lifestyle and maintaining their health at the appropriate level.
Editorial: SESMO Special Issues
Authors: Jakeman Tony , Athanasiadis Ioannis , Hamilton Serena 
Published: February 2021

As the journal nears the end of its second official year, we are pleased to start accepting submissions to our first two Special Issues. The first Special Issue is on Resilience of complex coupled Socio-Technical-Environmental systems through the modeling lens with guest editors Tatiana Filatova, Tina Comes (4TU Resilience Engineering Centre), Christoph Hoelscher (ETH Zurich) and Juliet Mian (Resilence Shift). This Special Issue aims to bring together cutting-edge research and international practice to offer insights into the latest scientific modelling methods, gaps, challenges and opportunities and best practice examples relating to operationalising resilience across a range of socio-technical-environmental applications. The second Special Issue is on Large-scale behavioural models of land use change with guest editors Calum Brown (Karlsruhe Institute of Technology), Tatiana Filatova (University of Twente), Birgit Müller (Helmholtz Centre for Environmental Research – UFZ), and Derek Robinson (University of Waterloo). This Special Issue is focussed on better understanding and modelling of temporal or spatial scales in land use dynamics.

We invite new proposals for Special Issues that fit within SESMO’s aims and scope. Our Special Issues are cohesive collections of articles focussed on a specific contemporary theme related to socio-environmental systems modelling. The Special Issue can build on previous work and research gaps, but can also explore new and emerging terrain relevant to our aims. Although the conceptualisation of a Special Issue may be initiated in a conference or workshop, it is critical that such a proposal also builds on the original dialogue. Articles should also be canvassed from across the globe. SESMO is an open access journal with no article processing or publication charges for authors. If you have a topic to propose, please contact us to discuss further.
Penerapan Model Pembelajaran Kooperatif Tipe Make A Match Pada Mata Pelajaran IPS Pokok Bahasan Perjuangan Dalam Mempersiapkan Kemerdekaan Indonesia Untuk Meningkatkan Hasil Belajar Siswa Kelas VA SDN Klatakan 01 Jember
Authors: Ismawati Yulia , Irvan Muhtadi , Zahroul Fitriyah Chumi 
Published: February 2021

Tujuan umum dalam penelitian ini adalah untuk meningkatkan hasil belajar siswa kelas VA SDN Klatakan 01 Jember melalui penerapan model pembelajaran kooperatif tipe Make A Match pada mata pelajaran IPS pokok bahasan perjuangan dalam mempersiapkan kemerdekaan Indonesia. Berdasarkan tujuan tersebut, latar belakang penelitian ini adalah rendahnya hasil belajar siswa kelas VA SDN Klatakan 01 Jember dalam pembelajaran IPS yang disebabkan pelaksanaan pembelajaran masih belum menerapkan model pembelajaran yang bervariatif sehingga siswa cenderung bosan. Salah satu upaya untuk meningkatkan hasil belajar siswa kelas VA SDN Klatakan 01 Jember dalam pembelajaran IPS adalah dengan menerapkan model pembelajaran kooperatif tipe Make A Match. Jenis penelitian ini adalah Penelitian Tindakan Kelas (PTK) yang terdiri dari 2 siklus dengan 4 tahapan yaitu perencanaan, pelaksanaan, pengamatan, dan refleksi. Subjek penelitian adalah siswa kelas VA SDN Klatakan 01 Jember yang berjumlah 22 siswa, yang terdiri atas 12 siswa laki-laki dan 10 siswa perempuan. Metode pengumpulan data dilakukan dengan wawancara, observasi, dokumentasi, dan tes. Hasil penelitian menunjukkan bahwa penerapan model pembelajaran kooperatif tipe Make A Match pada mata pelajaran IPS pokok bahasan perjuangan dalam mempersiapkan kemerdekaan Indonesia dapat meningkatkan hasil belajar siswa kelas VA SDN Klatakan 01 Jember. Skor rata-rata hasil belajar siswa pada prasiklus sebesar 64,81 meningkat menjadi 71,32 pada siklus I dan meningkat lagi menjadi 76,21 pada siklus II.

Kata Kunci: hasil belajar siswa, model pembelajaran kooperatif tipe make a match, penelitian tindakan kelas.
Exploration Factors Influencing Self-Efficacy in Patients with Heart Disease: A Literature Review
Authors: Purnomo Aris , Herawati Tuti , Yoona Sri 
Published: February 2021

Heart disease is the top cause of death worldwide. Self-efficacy is one of the fundamental factors contributing to self-management programs among patients with heart disease. Cardiac patients with good self-efficacy will participate in disease management, improve health status, better self-care behavior, and a higher level of quality of life. Factors affecting self-efficacy need to be identified for stratified plan intervention strategies; therefore, the goal will achieve significantly. The Purpose of this study to identify factors that influence self-efficacy in patients with heart disease. Literature research from 2013-2019, obtained from the five largest databases consist of Pubmed, Google Scholar, CINAHL, Medline and PsycINFO by using keywords "Self Efficacy," "Cardiovascular Disease," "Heart Disease," and "Self Efficacy and Cardiovascular Disease "and Self Efficacy and Heart Disease". Five articles were further analyzed, and ten factors affecting self-efficacy are: 1) Age, 2) Income, 3) Social-economy, 4) Body mass index, 5) Experience on health education, 6) Risk factors awareness, 7) Social support, 8) Depressive symptoms, 9) Adherence and 10) Physical activity. The influence factors of self-efficacy, including demographic characteristics, clinical status, health education, awareness of risk factors, and psychosocial.