bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk factors for mortality in preterm infants with necrotizing enterocolitis: a retrospective multicenter analysis
Authors: Kordasz Marcin , Racine Michaël , Szavay Philipp , Lehner Markus , Krebs Thomas , Luckert Christian , Hau Eva-Maria , Berger Steffen , Kessler Ulf 
Published: October 2021

AbstractIt is difficult to predict the risk of mortality in necrotizing enterocolitis (NEC). This study aimed at identifying risk factors for severe NEC (Bell stage III) and mortality in preterm children with NEC. In this multicenter retrospective study, we analyzed multiple data from 157 premature children with confirmed NEC in the period from January 2007 to October 2018. We performed univariate, multivariate, stepwise logistic regression, and receiver operator characteristics (ROC) analyses. We were able to demonstrate that low Apgar scores (notably at 1′ and 5′), low hemoglobin concentration (Hgb), and high lactate level at disease onset and during disease correlated with NEC severity and mortality (P < 0.05, respectively). Severe NEC was related to congenital heart disease (CHD — OR 2.6, CI95% 1.2–5.8, P 0.015) and patent ductus arteriosus (PDA — OR 3.3, CI95% 1.6–6.9, P 0.0012), whereas death was related to the presence of PDA (OR 5.5, CI95% 2.3–14, P < 0.001).Conclusion: Low Apgar scores, low Hgb, high lactate levels, and the presence of CHD or PDA correlated with severe NEC or mortality in children with NEC.

What is Known:• It remains difficult to predict which infant that suffers from necrotizing enterocolitis at risk of death.• Several clinical and laboratory parameters tools to predict fatal outcome in NEC.

What is New:• The following laboratory parameters were associated with the risk of death from NEC: Hemoglobin concentration, base excess and lactate level.• The following clinical variables were associated with the risk of death from NEC: Apgar scores, as well as the presence of congenital heart disease and patent ductus arteriosus.
Combined use of multimodal techniques for the resection of glioblastoma involving corpus callosum
Authors: Cui Meng , Chen Hewen , Sun Guochen , Liu Jialin , Zhang Meng , Lin Hepu , Sun Caihong , Ma Xiaodong 
Published: October 2021

Abstract
Purpose
To compare the multimodal techniques (including neuronavigation, intraoperative MRI [iMRI], and neuromonitoring [IONM]) and conventional approach (only guided by neuronavigation) in removing glioblastoma (GBM) with corpus callosum (CC) involvement (ccGBM), their effectiveness and safety were analyzed and compared.

Methods
Electronic medical records were retrospectively reviewed for ccGBM cases treated in our hospital between January 2016 and July 2020. Patient demographics, tumor characteristics, clinical outcomes, extent of resection (EOR), progression-free survival (PFS), and overall survival (OS) were obtained and compared between the multimodal group (used multimodal techniques) and the conventional group (only used neuronavigation). Both groups only included patients that had maximal safe resection (not biopsy). Postoperative radiochemotherapy was also performed or not. Univariate and multivariate analyses were performed to identify significant prognostic factors and optimal EOR threshold.

Results
Finally 56 cases of the multimodal group and 21 cases of the conventional group were included. The multimodal group achieved a higher median EOR (100% versus 96.1%, P = 0.036) and gross total resection rate (60.7% versus 33.3%, P = 0.032) and a lower rate of permanent motor deficits (5.4% versus 23.8%, P = 0.052) than the conventional approach. The multimodal group had the longer median PFS (10.9 versus 7.0 months, P = 0.023) and OS (16.1 versus 11.6 months, P = 0.044) than the conventional group. Postoperative language and cognitive function were similar between the two groups. In multivariate analysis, a higher EOR, radiotherapy, and longer cycles of temozolomide chemotherapy were positive prognostic factors for survival of ccGBM. An optimal EOR threshold of 92% was found to significantly benefit the PFS (HR = 0.51, P = 0.036) and OS (HR = 0.49, P = 0.025) of ccGBM.

Conclusion
Combined use of multimodal techniques can optimize the safe removal of ccGBM. Aggressive resection of EOR > 92% using multimodal techniques combined with postoperative radiochemotherapy should be suggested for ccGBM.
Glycan characteristics of human heart constituent cells maintaining organ function: relatively stable glycan profiles in cellular senescence
Authors: Itakura Yoko , Sasaki Norihiko , Toyoda Masashi 
Published: October 2021

AbstractCell surface glycoproteins, which are good indicators of cellular types and biological function; are suited for cell evaluation. Tissue remodeling using various cells is a key feature of regenerative therapy. For artificial heart remodeling, a mixture of heart constituent cells has been investigated for organ assembly, however, the cellular characteristics remain unclear. In this study, the glycan profiles of human cardiomyocytes (HCMs), human cardiac fibroblasts (HCFs), and human vascular endothelial cells (ECs) were analyzed using evanescent-field lectin microarray analysis, a tool of glycan profiling, to clarify the required cellular characteristics. We found that ECs had more “α1-2fucose” and “core α1-6fucose” residues than other cells, and that “α2-6sialic acid” residue was more abundant in ECs and HCMs than in HCFs. HCFs showed higher abundance of “β-galactose” and “β-N-acetylgalactosamine” residues on N-glycan and O-glycan, respectively, compared to other cells. Interestingly, cardiac glycan profiles were insignificantly changed with cellular senescence. The residues identified in this study may participate in organ maintenance by contributing to the preservation of glycan components. Therefore, future studies should investigate the roles of glycans in optimal tissue remodeling since identifying cellular characteristics is important for the development of regenerative therapies.
Developing a Social Evolutionary Measure of Child and Adolescent Hedonic and Eudaimonic Wellbeing in Rural Sierra Leone
Authors: Symonds Jennifer E. , Sloan Seaneen , Kearns Michelle , Devine Dympna , Sugrue Ciaran , Suryanaryan Sachita , Capistrano Daniel , Samonova Elena 
Published: October 2021

AbstractThe study establishes the validity of a new measure of child and adolescent hedonic and eudaimonic wellbeing designed for international use and based on social evolutionary theory. The measure advances the fields of psychometrics and happiness studies by providing the first a-contextual assessment of both hedonic and eudaimonic wellbeing that is suitable for use with children and adolescents. The Child and Adolescent Personal and Social Assessment of Wellbeing contains a brief measure (8-items) of children’s global hedonia and eudaimonia, and domain specific measures (8-items each) of children’s wellbeing in relation to peers, teachers, and families. To develop the measure, we conducted a mixed methods investigation in rural Sierra Leone. We researched the ecological validity of the conceptual framework in a qualitative study of 40 participants (19 children and 21 adults) living in two communities. We developed the quantitative items through a two-phase pilot study of 200 children living in ten communities. We examined the psychometric properties of the measure in the pilot study data, and in a larger dataset generated with 2324 children living in 95 communities. The qualitative results showed that the participants experienced the framework components (e.g., social acceptance) in their daily lives, and that each component was intertwined with indigenous perspectives on child wellbeing. The quantitative results demonstrated that the measure had good dimensional, concurrent, and predictive validity.
Implementation of ACTS into sPHENIX Track Reconstruction
Authors: Osborn Joseph D. , Frawley Anthony D. , Huang Jin , Lee Sookhyun , Costa Hugo Pereira Da , Peters Michael , Pinkenburg Christopher , Roland Christof , Yu Haiwang 
Published: October 2021

AbstractsPHENIX is a high energy nuclear physics experiment under construction at the Relativistic Heavy Ion Collider at Brookhaven National Laboratory (BNL). The primary physics goals of sPHENIX are to study the quark-gluon-plasma, as well as the partonic structure of protons and nuclei, by measuring jets, their substructure, and heavy flavor hadrons in $$p$$
p
$$+$$
+
$$p$$
p
, p + Au, and Au + Au collisions. sPHENIX will collect approximately 300 PB of data over three run periods, to be analyzed using available computing resources at BNL; thus, performing track reconstruction in a timely manner is a challenge due to the high occupancy of heavy ion collision events. The sPHENIX experiment has recently implemented the A Common Tracking Software (ACTS) track reconstruction toolkit with the goal of reconstructing tracks with high efficiency and within a computational budget of 5 s per minimum bias event. This paper reports the performance status of ACTS as the default track fitting tool within sPHENIX, including discussion of the first implementation of a time projection chamber geometry within ACTS.
Negativity Spreads More than Positivity on Twitter After Both Positive and Negative Political Situations
Authors: Schöne Jonas Paul , Parkinson Brian , Goldenberg Amit 
Published: October 2021

AbstractWhat type of emotional language spreads further in political discourses on social media? Previous research has focused on situations that primarily elicited negative emotions, showing that negative language tended to spread further. The current project extends existing knowledge by examining the spread of emotional language in response to both predominantly positive and negative political situations. In Study 1, we examined the spread of emotional language in tweets related to the winning and losing parties in the 2016 US elections, finding that increased negativity (but not positivity) predicted content sharing in both situations. In Study 2, we compared the spread of emotional language in two separate situations: the celebration of the US Supreme Court approval of same-sex marriage (positive) and the Ferguson unrest (negative), finding again that negativity spread further. These results shed light on the nature of political discourse and engagement.
The Role of Long Term Label-Retaining Cells in the Treatment of Erectile Dysfunction by Vacuum Erectile Device
Authors: Yang Baibing , Luse Dustin , Cao Yanna , Ko Tien , Wang Run 
Published: October 2021

Abstract

Introduction
Vacuum erectile device (VED) therapy is commonly used for penile rehabilitation after radical prostatectomy, however, the underlying mechanism of this effect is not fully understood.

Aim
To evaluate the presence of label-retaining cells (LRCs), cells with long-term retention of 5-ethynyl-2-deoxyuridine (EdU) labeling and recognized as adult stem cells or progenitor-like cells, in cavernous tissue after VED treatment using a BCNC rat model.

Methods
Postnatal pups (1 day old) of Sprague Dawley (SD) rats were intraperitoneally injected with EdU (50 ug/g, BID for 3 days) and BCNC surgery was conducted at 6 weeks old (designated as natal-labeled rats). Adult SD rats underwent BCNC surgery and EdU injection (50 ug/g, once) after surgery (designated as adult-labeled rats). One week after surgery, both natal- and adult-labeled rats received daily VED treatment for 4 weeks. Intracavernous pressure (ICP) and mean arterial pressure (MAP) were measured for all rats and then the penile tissue was harvested. The ratio of ICP/MAP was calculated to represent erectile function. Penile tissue was examined by immunofluorescence staining to detect EdU positive cells.

Main Outcome Measures
The ratio of Intracavernous pressure (ICP) /MAP and the percentage of EdU positive cells were measured.

Results
The erectile function was impaired after BCNC and partially restored after VED treatment in both natal- and adult-labeled rats (P &lt; .05). There was no difference in the percentage of EdU positive cells in natal-labeled rat cavernous tissue in BCNC group compared with VED group. Among the adult-labeled rats, the percentage of EdU positive cells increased in BCNC group (P &lt; .05) but didn't change significantly after VED treatment (P = .35).

Conclusion
LRCs may play a limited role in the restoration of erectile dysfunction through VED treatment after BCNC.
Exploring posthuman ethics: opening new spaces for postqualitative inquiry within pedagogies of the circular economy
Authors: Kopnina Helen 
Published: October 2021

AbstractThis article discusses closed-loop systems, namely Cradle to Cradle and circular economy, in the context of sustainable education. These circular models, at least ideally, promise absolute decoupling of resource consumption from the economy. This article presents student assignments applying these models to Hennes & Mauritz, a clothing retail company, and insect food producer, Protix.While the discussion of circular economy revolves around the economic benefits of closed-loop systems, it rarely addresses posthumanism. Posthumanism is related to postqualitative theory, inspired by Gilles Deleuze and Felix Guattari. Deleuze and Guattari emphasize that nature has become intertwined with technology and culture. In the cases discussed, combining both techno- and organic materials produces ‘monstrous hybrids’. It appears that fully circular solutions are rare as absolute decoupling is limited by thermodynamic (im)possibilities. This realization still has to be developed in environmental education. Within this posthumanist inquiry, the larger lesson from the case studies is the necessity of teaching about degrowth in production, consumption and corporate strategy. In pedagogical terms, this article aims to generate a more critical discussion within the environmental education community about how postqualitative inquiry can provide different and distinct perspectives from qualitative inquiry in the context of the circular economy.
Is Virtual Team-Based Learning Feasible and Effective in Teaching Neurolocalisation?
Authors: Ong Kim Yao , Gan Adelia Shin Ping , Rajalingam Preman , Tan Nigel C.K. , Tan Kevin 
Published: October 2021

ABSTRACT:We investigated the feasibility and effectiveness of virtual team-based learning (TBL) in teaching neurolocalisation (NL) in a sample of 18 student volunteers. Student satisfaction and knowledge outcomes were evaluated using the modified TBL Student Assessment Instrument and Extended Matching Questionnaire (EMQ), respectively. Mean student satisfaction rating was good at 3.9 out of 5.0 (SD 0.3). Participants achieved high mean EMQ scores of 84.2% (SD 2.9) with moderate correlation between individual assessment scores and EMQ scores (ρ = 0.587, p = 0.01). Virtual TBL is feasible for teaching NL with good student satisfaction and knowledge outcomes.
Aménagement d'ambons dans une église rurale récemment découverte à Koustilya (Sud-ouest de la Tunisie)
Authors: Chetoui Mourad 
Published: October 2021

AbstractThere were two excavation missions at the site of Koustilya, in 2017 and in 2018, to investigate the remains of a late rural church. The excavations identified the monument as a building for Christian worship. The architecture of this monument (three aisles and an apse and associated rooms) suggests a Christian church. This church enriches the list of rural Christian churches in Tunisia and additionally has some special features: among the architectural components discovered in this church are two fixed ambons built into the masonry. These give this church a particular importance, somewhat unique when compared to other Christian churches in the ancient Maghreb.
The feasibility of a peer support intervention to encourage adoption and maintenance of a Mediterranean diet in established community groups at increased CVD risk: the TEAM-MED EXTEND study: a pilot cluster randomised controlled trial
Authors: O’Neill Roisin F. , McGowan Laura , McEvoy Claire T. , Wallace Sara Megan , Moore Sarah E. , McKinley Michelle C. , Kee Frank , Cupples Margaret E. , Young Ian S. , Woodside Jayne V. 
Published: October 2021

AbstractThis study aimed to evaluate the feasibility of a peer support intervention to encourage adoption and maintenance of a Mediterranean diet (MD) in established community groups where existing social support may assist the behaviour change process. Four established community groups with members at increased Cardiovascular Disease (CVD) risk and homogenous in gender were recruited and randomised to receive either a 12-month Peer Support (PS) intervention (PSG) (n 2) or a Minimal Support intervention (educational materials only) (MSG) (n 2). The feasibility of the intervention was assessed using recruitment and retention rates, assessing the variability of outcome measures (primary outcome: adoption of an MD at 6 months (using a Mediterranean Diet Score (MDS)) and process evaluation measures including qualitative interviews. Recruitment rates for community groups (n 4/8), participants (n 31/51) and peer supporters (n 6/14) were 50 %, 61 % and 43 %, respectively. The recruitment strategy faced several challenges with recruitment and retention of participants, leading to a smaller sample than intended. At 12 months, a 65 % and 76·5 % retention rate for PSG and MSG participants was observed, respectively. A > 2-point increase in MDS was observed in both the PSG and the MSG at 6 months, maintained at 12 months. An increase in MD adherence was evident in both groups during follow-up; however, the challenges faced in recruitment and retention suggest a definitive study of the peer support intervention using current methods is not feasible and refinement based on the current feasibility study should be incorporated. Lessons learned during the implementation of this intervention will help inform future interventions in this area.
Sustainable Green Finance towards a Green Belt and Road
Authors: GOH Allison 
Published: October 2021

AbstractAt the second Belt and Road forum in 2019, the Chinese government set out its intentions to develop a “Green Belt and Road”. This paper will examine critical issues arising from green-financed projects under the Belt and Road. In particular, the root issue of the lack of harmonized sustainability standards for green bonds globally. While there are positive regulatory developments, there is still a big gap between companies’ reporting metrics and investors’ growing expectations of what constitutes “green”—constituting “green washing”. This issue compounds as green projects under the Belt and Road are often complex infrastructure projects, where unexpected (and negative) externalities may sometimes occur on the ground. In this regard, this paper advocates for robust risk management, where accurate forecasting of environmental harm and stakeholder engagement are implemented actively throughout the project's life cycle. Finally, adequate dispute resolution and avoidance measures should be adopted to protect stakeholders.
Coevolution of Weathering Front and Water Table
Authors: Wang Wei , Chen Po , Dueker Ken , Zhang Ye , Lee En‐jui , Mu Dawei , Keifer Ian , Jiao Jianying 
Published: October 2021

AbstractWater is known to play an essential role in initiating and maintaining subsurface weathering reactions. However, the interaction between the weathering front and the water table is unclear and under intense debate. Here, we present a high‐fidelity, 3D image of a variably saturated weathering front beneath a granite terrain in the Laramie Range, Wyoming, constructed using full‐3D ambient‐noise adjoint tomography and calibrated with data from an extensive drilling and hydraulic well testing effort. The imaged weathering front between saprolite and weathered bedrock is overall shallower than the water table under ridge but deeper than water table under valleys. We propose that downward‐advancing weathering front coevolves with water table in a positive cycle that gradually flattens the water table, enhances the rate of groundwater drainage, and exposes underlying bedrock to weathering. As a result, we expect this cycle to become “sluggish” with time as water table gradient decreases.
Photon-counting distributed free-space spectroscopy
Authors: Yu Saifen , Zhang Zhen , Xia Haiyun , Dou Xiankang , Wu Tengfei , Hu Yihua , Li Manyi , Shangguan Mingjia , Wei Tianwen , Zhao Lijie , Wang Lu , Jiang Pu , Zhang Chengjun , You Lixing , Tao Leigang , Qiu Jiawei 
Published: October 2021

AbstractSpectroscopy is a well-established nonintrusive tool that has played an important role in identifying and quantifying substances, from quantum descriptions to chemical and biomedical diagnostics. Challenges exist in accurate spectrum analysis in free space, which hinders us from understanding the composition of multiple gases and the chemical processes in the atmosphere. A photon-counting distributed free-space spectroscopy is proposed and demonstrated using lidar technique, incorporating a comb-referenced frequency-scanning laser and a superconducting nanowire single-photon detector. It is suitable for remote spectrum analysis with a range resolution over a wide band. As an example, a continuous field experiment is carried out over 72 h to obtain the spectra of carbon dioxide (CO2) and semi-heavy water (HDO, isotopic water vapor) in 6 km, with a range resolution of 60 m and a time resolution of 10 min. Compared to the methods that obtain only column-integrated spectra over kilometer-scale, the range resolution is improved by 2–3 orders of magnitude in this work. The CO2 and HDO concentrations are retrieved from the spectra acquired with uncertainties as low as ±1.2% and ±14.3%, respectively. This method holds much promise for increasing knowledge of atmospheric environment and chemistry researches, especially in terms of the evolution of complex molecular spectra in open areas.
Foveated glasses-free 3D display with ultrawide field of view via a large-scale 2D-metagrating complex
Authors: Hua Jianyu , Hua Erkai , Zhou Fengbin , Shi Jiacheng , Wang Chinhua , Duan Huigao , Hu Yueqiang , Qiao Wen , Chen Linsen 
Published: October 2021

AbstractGlasses-free three-dimensional (3D) displays are one of the game-changing technologies that will redefine the display industry in portable electronic devices. However, because of the limited resolution in state-of-the-art display panels, current 3D displays suffer from a critical trade-off among the spatial resolution, angular resolution, and viewing angle. Inspired by the so-called spatially variant resolution imaging found in vertebrate eyes, we propose 3D display with spatially variant information density. Stereoscopic experiences with smooth motion parallax are maintained at the central view, while the viewing angle is enlarged at the periphery view. It is enabled by a large-scale 2D-metagrating complex to manipulate dot/linear/rectangular hybrid shaped views. Furthermore, a video rate full-color 3D display with an unprecedented 160° horizontal viewing angle is demonstrated. With thin and light form factors, the proposed 3D system can be integrated with off-the-shelf purchased flat panels, making it promising for applications in portable electronics.