bluuebunny/crossref_metadata_2025_split huggingface dataset:
Carnet de bord Covid au sein d’un hôpital parisien
Authors: Pialoux Gilles 
Published: October 2021

La pandémie Covid-19 est toujours terriblement d’actualité à l’heure ou ce numéro des Tribunes de la Santé est sous presse. La carte interactive de l’université Johns-Hopkins affole les compteurs de la troisième pandémie mondiale : 160 513 476 cas dans le monde, 3 333 690 décès avec la France en quatrième position (107 280). Avec plus d’un milliard trois cent mille doses de vaccins administrées, la « course contre la montre », selon les termes du Conseil scientifique, est engagée entre vaccination universelle et universalisme des variants. Pourtant en décrue de la troisième vague en France, la lutte contre la Covid a quitté les rives de la science et de la santé publique pour devenir un sujet politique. Parce qu’il peut sembler que, lors de cette troisième vague, certains décideurs ou observateurs ont oublié ce qui s’est passé depuis l’émergence du Sars-CoV-2 à Wuhan (Chine), il est fait ici une place au récit de l’intérieur de la blouse blanche. Celle du chef du service des maladies infectieuses à l’hôpital Tenon, à Paris. La suite d’un carnet de bord en partie objet d’un livre 1 tenu de janvier 2020 à mai 2021 d’un combat harassant et terrifiant. Pour ne pas oublier mais aussi pour témoigner de comment les soignants et l’ensemble de l’hôpital se sont adaptés et ont tenu le choc face à la marée montante de la Covid-19. Comme pour le sida il nous faudra raconter et témoigner. Et revenir sur l’impréparation des services sanitaires français, européens, face à une telle pandémie.
Entre invisibilisation et visibilisation du travail : une contribution de la didactique professionnelle à la reconnaissance des compétences professionnelles des femmes de chambre
Authors: Ciavaldini-Cartaut Solange , Balas Stéphane 
Published: October 2021

Cet article s’intéresse au processus « d’invisibilisation et de visibilisation » du travail des femmes de chambre dans le secteur hôtelier (de trois étoiles ou plus) à partir de l’analyse de l’activité de travail fondée sur le cadre conceptuel de la didactique professionnelle. Les résultats documentent un conflit de logique entre « l’invisibilité érigée en norme de qualité » par le management des services d’étages et la recherche de reconnaissance professionnelle des femmes de chambre. Ces résultats soulignent également le contraste entre les compétences de celles qui sont formées et de celles simplement dotées d’une certification. Ces dernières se révèlent plus exposées aux risques professionnels surtout dans les chaines hôtelières. Les préconisations faites pour le Certificat d’Aptitude Professionnelle rénové « Commercialisation et service en hôtel-café-restaurant » qui sont fondées sur les résultats de cette étude soutiennent le processus de « visibilisation » du travail d’une élite au sein des professionnels du nettoyage .
Studying the Effect of Particulate Matter as SARS-CoV-2 Transmitters
Authors: Hakami Abdulrahim R. , Dobie Gasim 
Published: October 2021

Background Studies of risk factors are especially valuable at this difficult time in the midst of a pandemic. High levels of particulate matter (PM) represent a serious risk factor on health. While this is a direct impact on health, indirect effects are worth considering too. Design and methods The aim of this study was to investigate the role of PM in the transmission of viruses, especially SARSCoV- 2. Also, we sought to understand dynamics of PM in still air at high and low altitudes. Historic AQI and physical PM measurements were collected between August and September 2020 using air quality detector. Potential correlations between the number of total confirmed COVID-19 cases and average air quality index (AQI) from varied geographic locations were also assessed. Results Airborne PM levels were weakly associated with COVID-19 cases after analysing 77 territories. PM remained longer in the air at high altitudes compared to measurements made at sea level. This suggests that the link between PM and COVID- 19 transmission could be aggravated in areas of high altitude. Conclusions This article highlights that particulate matter can be involved in SARS-CoV-2 transmission. However, confounding factors may have impacted the association between the two variables. These findings can serve as a foundation for future studies on the effect of air pollutants and fine particulate matter on viral transmission.
Anterior Subconjunctival Anesthesia for Manual Small Incision Cataract Surgery
Authors: Ajay K. , Subhasree Revuru Kanaka , Poka Avinash 
Published: October 2021

Purpose:
To compare the effectiveness of anterior subconjunctival anesthesia (ASCA) with sub-tenon's anesthesia (STA) for manual small incision cataract surgery (MSICS), regarding pain, akinesia, surgeon comfort, and complications.

Methods:
This trial randomized 164 patients into two groups. Group 1 received ASCA, and Group 2 received STA. MSICS was performed on all patients. Any complications of anesthesia were noted before starting surgery. Patient ocular motility during surgery was scored between 0 and 4 based on the number of directions of gaze in which movement persisted. Following surgery, patients scored pain felt during surgery on a visual pain-score analog, and the surgeon graded for “discomfort” felt during surgery from 0 (Nil) to 4 (additional anesthesia needed).

Results:
Chemosis due to anesthesia and persistence of ocular motility in all four gaze directions were seen in all 82 patients of Group 1, but these did not prevent the surgeon from performing MSICS. Seventy-seven patients (94%) in Group 1 and 79 (96.4%) in Group 2 had no or mild pain during surgery. The surgeon had moderate-to-severe discomfort in 14 (17.2%) Group 1 patients and 3 (3.6%) Group 2 patients, most of whom had deep-set eyes or exhibited excessive eye movements. Two patients in Group 1 and one patient in Group 2 were converted to peribulbar block.

Conclusion:
ASCA is a safe and effective alternative for performing MSICS. It does not induce akinesia but provides adequate anesthesia for the surgery in most patients, except those with deep-set eyes, especially if displaying increased anxiety.
Management of patients with synchronous head-and-neck and lung cancers
Authors: Paleiron Nicolas , Gervais Radj , Rousseau-Bussac Gaelle , Game Laurence Bigay , Chiappa Anne Marie , Lamy Regine , Guisier Florian , Le Caer Hervé , Robinet Gilles , Bizieux Acya , Chouaïd Christos 
Published: October 2021

Purpose:
Few data have been published on the management of patients with synchronous head-and-neck cancer (HNC) and lung cancer (LC). This observational study was undertaken to describe the management of these patients in multiple centers.

Materials and Methods:
All patients consecutively diagnosed with synchronous HNC and LC in 26 French centers were included. Information was collected on patients' clinical characteristics, management, and outcomes. Those characteristics and treatments were analyzed descriptively. Kaplan–Meier progression-free and overall survival probabilities were estimated.

Results:
The study included 132 patients: 83% male; median age: 63.7 (range: 62.1–65.4) years; all current or former smokers; Eastern Cooperative Oncology Group performance status: 0 or 1 for 21.9% or 65.9% of the patients, respectively; cardiovascular comorbidities: 63%; chronic obstructive pulmonary disease: 33%; and previous cancer: 11%. HNC histology was 98% squamous: 23.5% oral cavity, 26.5% oropharyngeal, 22.0% hypopharyngeal, and 28.0% laryngeal. LCs were mainly localized (47.7% Stage I and 9.9% Stage II): 38% squamous, 49% adenocarcinomas, and 13% others. LC diagnosis impacted HNC management for 38% of the patients, with a median time from HNC diagnosis to first HNC treatment of 40 days. HNC impacted LC management for 48% of the patients, with a median time from LC diagnosis-to-LC treatment interval of 41 days.

Conclusions:
Synchronous LC at HNC diagnosis impacted management and outcomes of both cancers. Specific recommendations should be elaborated to improve the management of these patients.
Evaluation of the quality of life of patients with maxillofacial defects after prosthodontic rehabilitation
Authors: Matapathi Neelanjali , Shenoy Vidya K. , Shenoy Ramya , Miranda Glynis A. , Upadhya Mithun , Mehendale Avinash , Bangera Blessy , Shenoy K. Kamalaksh 
Published: October 2021

Context:
Oral cancer surgery leads to hard- and soft-tissue loss which can affect the quality of life of the individuals. Maxillofacial prosthodontics focuses on optimizing the disrupted oral function of individuals whose rehabilitation will serve as a psychosocial therapy.

Aim:
The aim of this study was to assess the oral health-related quality of life (OHRQoL) after the maxillofacial prosthetic rehabilitation following cancer resection surgery.

Settings and Design:
The sample comprised 15 oral cancer patients who agreed to maxillofacial prosthesis (MFP) after surgery.

Materials and Methods:
Oral function and OHRQoL were evaluated pre- and postmaxillofacial prosthetic rehabilitation. The masticatory function, swallowing function, and articulatory function were evaluated. The OHRQoL was evaluated by OHIPJ-14 questionnaire. Descriptive methods such as frequency, percentage, mean, and standard deviation were calculated.

Statistical Analysis:
Descriptive statistics was used to analyze the results.

Results:
A statistically significant difference was observed between prescores and postscores of dysphagia score (P = 0.05) and OHIP-J14 score (P = 0.00). No statistically significant differences were evident in perceived chewing ability (P = 0.29) and intelligibility score (P = 0.43). A statistically significant difference was evident in the prescore and postscore of OHIP-J14 subscales: functional limitations (P < 0.05), physical pain (P < 0.05), psychological discomfort (P < 0.05), physical disability (P < 0.05), psychological disability (P < 0.05), and handicap (P < 0.05), before and after maxillofacial prosthetic treatment except for social disability (P > 0.05).

Conclusion:
OHRQoL significantly improved with maxillofacial prosthetic rehabilitation.
Comparative outcomes of short-term and long-term fractionation with temozolomide in older glioblastoma patients
Authors: Uysal Bora , Gamsiz Hakan , Sager Omer , Dincoglan Ferrat , Demiral Selcuk , Ozcan Fatih , Colak Onurhan , Beyzadeoglu Murat 
Published: October 2021

Background:
The main goal of our study is to comparatively evaluate outcomes of hypofractionation and long-term fractionation with temozolomide (TMZ) in glioblastoma patients older than 65 years.

Methods:
Eighty patients with glioblastoma meeting the eligibility criteria of >65 years of age, the Karnofsky performance score (KPS) >60, no previous radiotherapy (RT) to the brain referred to our department between October 2009 and October 2016 for adjuvant chemoradiotherapy after surgery were studied. The first group of patients received a dose of 6000 cGy in 30 fractions and the second group was delivered 4000 cGy in 15 fractions All patients used TMZ concomitantly with RT. We used the paired t-test and the Wilcoxon signed-rank test with Statistical Package for the Social Sciences, version 15.0 (SPSS, Inc., Chicago, IL, USA) software for statistical analysis.

Results:
Forty-six patients were men (57.5%), and 34 patients (42.5%) were woman. Median age was 68 years (range 66–87). Median KPS was 75 (range 60–100). Median follow-up time was 12 months (range 6–30). Median overall survival was 15.2 months and 14.3 months for patients with hypofractionation and conventional fractionation, respectively, with no statistical significance (P = 0.13).

Conclusion:
Hypofractionation should be recommended to the elderly glioblastoma patients older than 65 years because of the short treatment time, reduced acute adverse effects of both TMZ and RT compared to long-term fractionation.
Online Course in Geriatrics for Final-Year Medical Students
Authors: Bhatt Arun N. , Ganesh Gayatri , Adhikari Prabha , Ganesh Alka 
Published: October 2021

Background:
The new competency-based MBBS undergraduate curriculum articulates 24 competencies in geriatrics. Acknowledging the dearth of faculty in the country, a group of geriatricians developed and conducted an online modular course for final-year medical students.

Methods:
This 6-week online course included 13 modules and the study materials were developed through a two-stage vetting process. The course was advertised to potential students through social media and was delivered over Google classroom platform. Students' learning was assessed by multiple-choice questions (MCQs), and the course was evaluated with comparison of pretest and posttest, feedbacks from students with both structured and open-ended questionnaires.

Results:
Out of 200 eligible students from 38 medical colleges who applied, 142 students joined the course. Out of 142 students joined, 98 (69%) completed the course with 80% attendance; 91 (64.1%) secured scores above 50%; and 46 (32.4%) secured scores above 80% in MCQ test. Posttest scores were significantly higher than pretest scores (P < 0.001) with medium Cohen's effect size. Median scores of feedbacks on 20-point Likert scale for all modules were 15 or 16. Content analysis of qualitative feedback showed appreciation for the structure and content of the course, praise for the expertise and commitment of the faculty in delivering it effectively, scope for further improvement, and positive change in attitude toward discipline of geriatrics.

Conclusions:
This endeavor shows that short online course will be helpful for motivated medical students to expand their knowledge in geriatrics.
Knowledge, Attitudes, and Practices among Older Adults of Urban Rajasthan toward COVID-19
Authors: Goyal Laxmi Kant , Sharma Dharmesh Kumar , Wadhwani Dileep , Singhal Sunny , Mathur Arvind 
Published: October 2021

Introduction:
With no effective treatment in sight, preventive measures are the only effective way to fight coronavirus. As older adults are highly vulnerable in this pandemic, it is essential to understand and identify gaps in their knowledge, attitudes, and practices (KAP) regarding COVID-19 to address them. The study aimed to assess KAP among older adults of urban Rajasthan toward COVID-19 infection and its vaccination.

Materials and Methods:
The online cross-sectional survey was conducted in June 2021 using a questionnaire with close-ended questions on COVID-19 infection and vaccination with a convenience sample of 100 older adults above 60 years residing in Rajasthan. The questionnaire was developed and validated using Google Forms and circulated via social media.

Results:
The mean age of the participants was 68.2 years. Seventy-four were male and 72 had educational qualification graduate and above. They demonstrated a moderate level of KAP toward the coronavirus infection. However, <5% had completely correct score on either knowledge, attitude, or practices. Knowledge, attitude and practices of subjects regarding vaccination were good. 97% of the participants received at least one dose and 95% agreeing to recommend it to others too. However, only 36% knew that vaccine does not decrease immunity.

Conclusion:
Although older adults had reasonably good KAP relating to coronavirus infection and its vaccination, there are still some misconceptions and malpractices. Further, information, education, and communication activity can promote their positive attitude toward preventive measures into good practice of self-imposed lockdown.
Role of enhanced recovery after surgery in total laparoscopic hysterectomy
Authors: Inania Mili , Sharma Priyanka , Parikh Manoj 
Published: October 2021

Introduction:
Enhanced recovery after surgery (ERAS) principles is an evidence-based surgical management approach that requires cooperation across various medical specialties. In this study, we applied ERAS principles in total laparoscopic hysterectomy (TLH) and the post-operative outcomes like post-operative pain, nausea and vomiting, opioid requirement, day of discharge, and any other complaints were studied.

Methods:
The study was conducted in a private healthcare setup in Jodhpur, Rajasthan, India. In this non-randomised controlled study 103 patients who underwent TLH over a period of 1 year were alternatively allocated to the study group and the control group. There were 51 patients in the study group in whom ERAS principles were applied and 52 patients in control group in whom traditional post-operative care was given.

Results:
Post-operative nausea and vomiting and opioid requirement were significantly reduced in the study group (P < 0.05). The post-operative pain was similar in both groups. The majority of patients in study group were discharged within 24 h as compared to the routine discharge after 48 h.

Conclusion:
Following ERAS principles in TLH results in decrease in post-operative nausea and vomiting, post-operative opioid requirement and hospital stay. Hence, the ERAS principles should be the standard practice in TLH even in a developing country setup.
Temporalis Fascia for the Management of Medial Rectus Damage Secondary to Endoscopic Sinus Surgery
Authors: Bagheri Abbas , Veisi Amirreza , Tavakoli Mehdi 
Published: October 2021

Purpose:
To report a challenging case of medial rectus (MR) damage secondary to endoscopic sinus surgery (ESS).

Methods:
A 37-year-old woman presented with diplopia, exotropia, and adduction deficit of the right eye due to the right MR injury secondary to the ESS.

Results:
As a stepwise approach, she respectively underwent repairing of the damaged MR plus ipsilateral lateral rectus recession, half-tendon vertical rectus transposition to the MR insertion, and eventually nasal globe fixation with temporalis fascia that ultimately provided a single vision in the primary position with orthophoria.

Conclusions:
Re-establishment of an acceptable field of a single binocular vision in the context of iatrogenic MR injury is challenging and often requires multiple step-wise operations. Temporalis fascia is a safe and strong autogenous material, which can be used for globe fixation in this setting.
In Vivo Confocal Microscopic Evaluation of Corneal Changes in Acute Endothelial Rejection
Authors: Latifi Golshan , Katoozpour Ramon , Ghaffari Reza , Abdi Parisa , Kasiri Maryam , Berijani Sahar 
Published: October 2021

Purpose:
To evaluate the microstructural corneal changes during acute endothelial graft rejection and following treatment using in vivo confocal microscopy (IVCM).

Methods:
Patients with a clinical diagnosis of severe acute endothelial graft rejection following penetrating keratoplasty were included in this study. IVCM was performed on the 1st day the patient presented with rejection signs and at the time of clinical resolution.

Results:
Twenty-three patients were included in this study. Inflammatory cells appeared as dendritic cells (DCs) and less frequently, as non-DCs in basal epithelial and subbasal areas. Activated keratocytes (AKs) (type 1: large cells with visible cytoplasmic processes; type 2: elongated and spindle-shaped keratocytes) were visible in acute phase. Following resolution, type 1 AKs considerably reduced, but type 2 cells were more often persisted. Multiple types of keratic precipitates (KPs) were also visible in acute phase which resolved following resolution of rejection.

Conclusions:
Acute graft rejection was associated with an increase in the number of DCs, activation of keratocytes, and aggregation of various types of KPs. Inflammatory process subsided in almost all cases, but the IVCM changes did not return to normal early after clinical resolution of rejection.
Vitreoretinal Surgery Amid Coronavirus Disease 2019 Pandemic Restrictions
Authors: Ilhan Cagri , Citirik Mehmet , Teke Mehmet Yasin 
Published: October 2021

Purpose:
To define the characteristics of vitreoretinal surgeries amid coronavirus disease 2019 (COVID-19) pandemic restrictions in Turkey.

Methods:
This descriptive, cross-sectional study was conducted for vitreoretinal surgeries during the 10-week period (during this period, all elective surgeries were postponed across the country by the order of the Republic of Turkey Ministry of Health) in a single tertiary referral hospital in Ankara, Turkey. The number of surgeries, surgical indications, risk factors, etiological factors, and associated conditions were investigated and compared with the clinical features of the patients who underwent vitreoretinal surgery in the same period of the recent year.

Results:
During this period, vitreoretinal surgery was performed more commonly for the male population (P < 0.001). The number of vitreoretinal surgeries was statistically significantly correlated with the number of COVID-19 cases (P = 0.006 and r = −0.791 for weekly numbers of new surgeries and cases, and P < 0.001 and r = 0.929 for cumulative numbers of surgeries and cases). Diabetes mellitus in 26 patients (32.9%) was the most common systemic comorbidity. The most common indication for vitreoretinal surgery was rhegmatogenous retinal detachment in 44 patients (55.7%) followed by diabetic retinopathy complications in 21 patients (26.6%). No one was operated on for vitreoretinal interface disorders during this period, and the rate of rhegmatogenous retinal detachment was higher than the same period of the recent year (P = 0.003).

Conclusions:
Amid COVID-19 pandemic restrictions in Turkey, the number of vitreoretinal surgeries was inversely associated with the number of confirmed COVID-19 cases. The male population needed more vitreoretinal surgery, and rhegmatogenous retinal detachment was the most common indication for all patients.
Pterygium Recurrence Rates in the Hispanic Population in the Northeastern United States
Authors: Fam Anthony , Vohra Reshma , Vadhar Neil R , Dastjerdi Mohammad H 
Published: October 2021

Purpose:
To determine the rate and factors affecting pterygium recurrence in the Hispanic population of the Northeastern United States, based on patient demographic information.

Methods:
In this retrospective cross-sectional study, data were collected on ethnically Hispanic patients from 2013 to 2018 who had primary single-headed pterygia excision and conjunctival autograft, with the minimum of 4-month follow-up time. This study was conducted in an academic institution in the Northeastern United States, with all patients being from the surrounding community.

Results:
In 168 Hispanic patients with confirmed primary single-headed pterygium, most pterygia occurred nasally (161/168). The average age of presentation was 46.3 ± 12.0 years (range, 23–77 years). There were 22 recurrences (13.1%), occurring at an average of 3.0 ± 1.6 months (1–8 months). This cohort demonstrated a unimodal recurrence distribution. Age is significantly inversely correlated with the incidence of recurrence (r = −0.219, P = 0.004), but not with the size of the recurrent pterygia (r = −0.112, P = 0.621). There was no significant difference between recurrence based on gender (P = 0.265), location (P = 0.824), or laterality (right or left eye) (P = 0.213). Mean corrected visual acuity improved from 20/40 to 20/32 after pterygium excision (P < 0.001). Cox regression analysis for age groups shows the risk of recurrence for patients aged 20–29 is 11.4-time that of patients aged 50 and above (P < 0.001).

Conclusions:
Recurrence occurred unimodally at around 3 months postoperatively. Younger patients are significantly more susceptible to recurrence. Future studies may seek to determine the incidence of pterygia and their recurrence patterns in relation to occupations and sun exposure time in a geographic area.