bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of Scientific Production in Ergonomics and Workplace Safety in the Last 20 Years: a Bibliometric Approach Using the Scopus Platform
Authors: Silva William Neves da , Lima Ewerton Henrique Bezerra , Oliveira Francisca Aline Pereira Maciel , Melo Marília Fernandes Soares de , Santos Marcio William Celestino dos , Paulo Wanessa Maria Araújo , Lima Maurício dos Santos Lima 
Published: December 2024

Objective: The main proposal of this work is to carry out a bibliometric analysis on the topic of ergonomics in occupational safety, focusing on publications from the last twenty years.

Theoretical Framework: Present a solid bibliographic survey on the subject of ergonomics and its variations, including possible illnesses resulting from inadequate practice of activities. In addition, connect this information with the context of good work practices for workers.

Method: The method used was bibliometric analysis, using R programming. The study's main proposal was to collect documents related to the theme of ergonomics from the last 20 years, using the Scopus research platform. The objective was to carry out a solid survey on the subjects related to this theme.

Results and Discussion: The analysis revealed a relatively low number of documents, with 243 results related to ergonomics and occupational safety, despite it being a constantly growing area and present in several sectors. The number of documents per year was presented, as well as the articles with the highest number of citations and their respective journals. These data indicate that there is still a long way to go in the dissemination of works focused on good safety practices in the context of ergonomics.

Research Implications: The analysis developed highlights the importance of the connection between academia and the professional sector, especially in relation to information on ergonomics. This connection is particularly relevant in crucial areas such as construction, industry and the hospital sector, which often face worker absences due to lack of communication or adequate knowledge on the subject.

Originality/Value: The main contribution of this study is to demonstrate the academic evolution in the subject of ergonomics, highlighting the bibliographic growth on the subject. This analysis may contribute to future publications related to the subject.
Oxidative Stress and the Severity of Gastroesophageal Reflux Disease: Is There Any Correlation?
Authors: Imro'ati Tri Asih , Sugihartono Titong , Widodo Budi , Nefertiti Eva Pravitasari , Wibawa I Dewa Nyoman 
Published: December 2024

Background: Oxidative stress plays a crucial role in the inflammatory response of the oesophageal epithelium; hence, therapies that affect oxidative stress may be a new approach in GERD management. The objective is to analyze and determine the correlation between Total Oxidant Status (TOS), Total Antioxidant Status (TAS), and Oxidative Stress Index (OSI) with severity of GERD.Methods: This is an observational analytic study using a cross-sectional design,that conducted at the Endoscopic Unit of three hospitals in Surabaya, which held from June 2020 to March 2021. The 18 to 60 years old subjects who meet the GERD-Q score 8-18 and not meet the exclusion criteria undergo an endoscopic examination to determine the GERD severity and blood test. Data analysis was using the Spearman rank correlation test.Results: This study indicates that most subjects are women, with mean age 39.31±10.99 years, most are GERD grade A, the mean value of TOS, TAS, ISO respectively is 5.18±1.60, 1.58±0.18, and 3.36±1.35. The laboratory test results show insignificant different based on GERD degree. There is a non-significant positive correlation between TOS and GERD severity, a significant negative correlation between TAS and GERD severity, and a significant positive correlation between OSI and GERD severity (respectively, r = 0.121, p = 0.266 vs r = -0.323, p = 0.044 vs r = 0.345, p = 0.033).Conclusion: The TAS and OSI may be correlated to the GERD severity but still need further investigations.Keywords: Gastroesophageal reflux disease, Oxidative Stress Index, Total Oxidant Status, Total Antioxidant Status
Prevalence and Risk Factors of Functional Dyspepsia: A Population-Based Study
Authors: Aydın Selami , Oner Can , Cetin Hüseyin , Simsek Engin Ersin 
Published: December 2024

Background: Functional dyspepsia is one of the most common functional gastrointestinal disorders and affects more than 20% of the population. This study aimed to determine the prevalence of functional dyspepsia according to Rome IV criteria and its relation with social determinants.Methods: This cross-sectional study was conducted in the Department of Family Medicine, Kartal Dr Lutfi Kırdar City Hospital Tuzla Training and Research Primary Health Care Center, Istanbul, Turkey from May - December 2019. The participants (aged 18-78) were selected using randomized sampling by a family physician according to the records. All participants underwent a clinical interview based on a questionnaire based on Rome IV criteria. The factors that were significant in the binary comparison were taken into logistic regression analysis (Backward: LR) to determine the causal relationship. P-values 0.05 were considered statistically significant.Results: A total of 350 participants were enrolled to the study (43.4 %; n=152 male and 56.6%; n=198 female). The prevalence of functional dyspepsia was 16.9% (n=59). 62.7% (n=37) of dyspeptic patients had epigastric pain syndrome and 67.8% (n=40) of them had postprandial distress syndrome. Daily tee consumption, body mass index, and family history were found as social factors related to functional dyspepsia.Conclusion: The prevalence of functional dyspepsia was 16.9% according to Rome IV criteria and most of the patients were female. Obesity was an important factor related to dyspepsia. Dyspeptic symptoms must investigate especially in obese female patients.Keywords: Dyspepsia, functional dyspepsia, prevalence
The Influence of the Anomalous Coupling on the in the Randall - Sundrum Model
Authors: Thi Ha Giang Bui 
Published: December 2024

A study to produce a Z boson and a radion through anomalous couplings is considered from muon-muon colliders at the center of mass energy 10 TeV. The leptonic decays of the Z boson and a radion decaying into a pair of photons are considered. The integrated luminosity of muon colliders is 10 . The production cross-sections depend on the polarization of initial beams, the center of mass energy . The minimum integrated luminosity value is shown to correspond to a significance larger than 5s.
Exosomes derived from cancer-associated fibrolasts mediated ciplatin resistance
Authors: Meng Yiyu , Shao Hui , Wu Lijun 
Published: December 2024

Objective:
Nasopharyngeal carcinoma (NPC), a highly invasive form of head and neck cancer, carries a significant risk of distant metastasis. NPC is particularly prevalent in Asia and has a high incidence in southern China. Cisplatin-diamminedichloroplatinum (DDP), a chemotherapy agent, is commonly employed in NPC treatment. Despite DDP’s efficacy, many patients eventually develop resistance to it over the course of their therapy, which significantly hinders treatment outcomes. Cancer-associated fibroblasts (CAFs) are key components of the tumor micro-environment and contribute to tumor progression and chemotherapy resistance. Exosomes secreted by CAFs serve as crucial mediators of intercellular communication and participate in modulating diverse biological processes. This study aimed to explore how exosomes derived from CAFs contribute to DDP resistance in NPC.

Material and Methods:
An in vitro coculture system was used to simulate the interaction between CAFs and NPC cells, and exosomes secreted by CAFs were isolated and characterized. The expression of autophagy hallmark proteins was detected by Western blot and quantitative real-time polymerase chain reaction. Autophagy intensity was quantified using monodansylcadaverine staining, and cell proliferation was assessed by colony formation assays and methylthiazolyldiphenyl–tetrazolium assays. NPC cells were treated with autophagy inducers (rapamycin), and the expression of Ras homologue enriched in brain (Rheb), mammalian target of rapamycin complex (mTORC1), and UNC51-like kinase was detected. Immunofluorescence was used to determine the cellular localization and expression intensity of mTORC1, and the effect on DDP sensitivity was evaluated through cell proliferation rates. In addition, the exosome-mediated resistance mechanism was further validated using an in vivo xenograft tumor model.

Results:
Coculture of CAFs with NPC cells significantly promoted the proliferation of NPC cells (P < 0.01), significantly elevated the IC50 value of DDP (P < 0.01), and elevated the resistance of NPC cells to DDP. CAF-derived exosomes elevated autophagy hallmark proteins light chain 3B-II, Beclin, and increased the autophagy intensity (P < 0.01). CAF-derived exosomes promoted autophagy by inhibiting mTORC1 (P < 0.01). In the in vitro model, exosomes promoted the growth of tumor tissues (P < 0.01), and the inhibition of exosome secretion reversed the promotion effect of autophagy (P < 0.01) and elevated the sensitivity of NPC cells to DDP.

Conclusion:
CAF-derived exosomes promote protective autophagy in NPC cells through the Rheb/mTOR axis, and result in DDP resistance in NPC.
Knocking-down annexin A3 suppresses inflammation, oxidative stress, apoptosis, and endoplasmic reticulum stress to attenuate sepsis-induced acute kidney injury in HK2 cells
Authors: Su Jie , Wang Lantao , Guan Xiaoying , Li Nan , Sun Lixiao 
Published: December 2024

Objective:
Sepsis-induced acute kidney injury (AKI) is considered as a life-threatening complication of sepsis. The purpose of this study is to clarify the involvement of annexin A3 (ANXA3) in sepsis-related AKI.

Material and Methods:
Lipopolysaccharide (LPS) was used to establish a cell model based on HK2 cells. ANXA3 expression was quantified through quantitative real-time polymerase chain reaction. Cell proliferative capacities were assessed through 5-ethynyl-2'-deoxyuridine proliferation, cell counting kit-8, and colony formation experiments. Flow cytometry was utilized to analyze apoptotic cells. Inflammatory and oxidative stress indicators were measured by employing corresponding commercial assay kits. Endoplasmic reticulum (ER) stress markers were quantified through western blot analysis.

Results:
ANXA3 levels were significantly elevated in HK2 cells treated with LPS and in serum samples obtained from patients with AKI and sepsis (P < 0.001). LPS treatment exacerbated cellular damage, leading to increased ER and oxidative stresses, apoptosis, and inflammation, whereas knocking down ANXA3 significantly reversed these changes (P < 0.001).

Conclusion:
Interference with ANXA3 protected HK2 cells from LPS-induced cell injury through inhibiting inflammation, oxidative stress, apoptosis, and ER stress.
Serum magnesium level in febrile children with or without simple febrile seizures from 6 months to 5 years of age: A case-control study
Authors: Kanwar Rajesh , Makwana Mohan , Choudhary Shyama , Choudhary Tamanna , Jat Suresh , Haritwal Priyanka 
Published: December 2024

Objectives:
Febrile seizure is the most common type of seizure (2–4%) in children. Imbalance in electrolytes, especially hypocalcemia and hypomagnesemia predispose to all seizures, including febrile seizures. The objective of this study was to compare the serum electrolytes, especially magnesium levels in febrile children presenting with and without episodes of simple febrile seizure.

Materials and Methods:
An institution-based age- and sex-matched case-control study done between May and October of 2022, involved 60 children aged 6 months to 5 years, divided into 30 cases (febrile children with seizure) and 30 controls (febrile children without seizure). Detailed history including past, birth, and family history was obtained, and serum magnesium, sodium, potassium, and calcium level estimations were done for each participant.

Results:
The mean serum magnesium of the febrile seizure group was 1.6 ± 0.8 mg/dL, while that for the control group was 2.2 ± 0.3 mg/dL. Similarly, the mean serum calcium levels of the study participants recruited to the febrile seizure group was 8.4 ± 1.1 mg/dL, while that for the participants recruited to the control group was 9.4 ± 0.5 mg/dL. On analysis, it was seen that the serum magnesium and calcium levels were significantly lower among cases than controls (P < 0.001). However, participants did not differ significantly between the two groups with respect to serum sodium and potassium levels.

Conclusion:
Mean serum magnesium and calcium levels of children suffering from simple febrile seizures were significantly lower than that of the control children, therefore maintaining optimum serum magnesium and calcium levels should be prioritized in febrile children to prevent the development of simple febrile children among them febrile seizure.
Pengaruh Keharmonisan Keluarga Terhadap Kenakalan Remaja di Kota Bandung
Authors: Januri Tasya Suci , Sardin Sardin , Utami Nindita Fajria 
Published: December 2024

AbstrakTerdapat berbagai macam faktor yang menyebabkan terjadi perilaku menyimpang pada remaja. Di antaranya ialah faktor keluarga. Keharmonisan keluarga tentu dapat menjadi salah satu faktor yang membuat remaja melakukan penyimpangan. Penelitian ini bertujuan untuk mengetahui pengaruh keharmonisan keluarga terhadap kenakalan remaja di Kota Bandung. Jenis penelitian ini ialah penelitian kuantitatif dengan Teknik pengambilan sampel menggunakan teknik Purposive Sampling yaitu remaja yang berdomisi di Kota Bandung dengan rentang usia 15-20 tahun sebanyak 105 responden. Metode pengumpulan data yang digunakan ialah dengan menyebarkan kuisioner. Alat analisis yang digunakan ialah analisis regresi linear berganda dengan menggunakan bantuan aplikasi SPSS versi 27. Hipotesis dari penelitian ini yaitu adanya pengaruh signifikan antara keharmonisan keluarga terhadap kenakalan remaja di Kota Bandung. Sedangkan hasil dari penelitian ini menunjukkan Hasil dari penelitian ini menunjukkan bahwa 1) terdapat hubungan yang linear antara kedua variabel, 2) Â terdapat pengaruh antara keharmonisan keluarga terhadap kenakalan remaja yang terjadi di Kota Bandung 3) pengaruh dari keharmonisan keluarga terhadap kenakalan remaja di Kota Bandung sebesar 21,5%.Kata kunci: keharmonisan kelurga; kenakalan remaja; Kota BandungÂ The Effect of Family Harmony on Juvenile Delinquency in Bandung CityAbstractThere are various factors that cause deviant behavior in adolescents. Among these are family factors. Family harmony can certainly be one of the factors that make teenagers commit deviations. This study aims to determine the effect of family harmony on juvenile delinquency in the city of Bandung. This type of research is quantitative research with sampling techniques using Purposive Sampling, namely adolescents domiciled in the city of Bandung with an age range of 15-20 years as many as 105 respondents. The data collection method used is to distribute questionnaires. The analysis tool used is multiple linear regression analysis using the help of the SPSS version 27 application. The hypothesis of this study is that there is a significant influence between family harmony and juvenile delinquency in the city of Bandung. While the results of this study show the results of this study show that 1) there is a linear relationship between the two variables, 2) there is an influence between family harmony on juvenile delinquency that occurs in the city of Bandung 3) the influence of family harmony on juvenile delinquency in the city of Bandung by 21.5%.Keywords: family harmony; juvenile delinquency; Bandung CityÂ
ВЛИЯНИЕ ГОСУДАРСТВЕННОГО ДОЛГА НА ОБЕСПЕЧЕНИЕ ЭКОНОМИЧЕСКОЙ БЕЗОПАСНОСТИ РЕГИОНА
Authors: Савина Т.Н. , Пониматкина Л.А. , Шилкина Т.Е. 
Published: December 2024

Как в экономической литературе, так и в кругах известных ученых, представителей органов власти, да и в целом общественности все чаще и активнее обсуждаются проблемы устойчивого и безопасного развития бюджетно-финансовой сферы. Особое внимание привлекают вопросы, касающиеся долговых государственных заимствований. В настоящей статье дана оценка состояния государственного долга, показано его влияние на обеспечение экономической безопасности. Составлен рейтинг субъектов РФ по уровню долговой нагрузки, что позволило определить место региона в нем по данному показателю. Разработана система индикаторов, которую можно использовать для исследования государственного долга. Для анализа состояния государственного долга в динамике 7 лет (в период с 2016 г. по 2022 г.) рассмотрены такие показатели как, коэффициент долговой нагрузки бюджета региона, расходы на обслуживание государственного долга в общем объёме расходов бюджета региона, коэффициент долговой зависимости экономики региона. В целях нейтрализации выявленных в процессе анализа угроз предложена стратегия по обеспечению экономической безопасности в финансово-бюджетной сфере региона, учитывающая тип региона и его состояние относительно зон риска. На основе построения авторегрессионной модели с помощью тренда полиноминальной функции нами была предпринята попытка спрогнозировать значения государственного долга.
Análisis del éxito académico mediante aprendizaje automático: adicción y ChatGPT
Authors: Torres-Diaz Juan Carlos , Reátegui Rojas Ruth María 
Published: December 2024

En este trabajo, se analiza la incidencia de las variables adicción al teléfono, a la pornografía, número de veces que se desbloquea el teléfono a cada hora y nivel de confianza en ChatGPT sobre el éxito académico de un grupo de 4278 estudiantes de ocho universidades de Ecuador. Se emplean los siguientes métodos: árboles de decisión (DT), random forest (RF) y support vector machine (SVM). Los resultados obtenidos señalan niveles similares en la precisión alcanzada en los tres algoritmos, respecto a la exactitud, en caso de SMOTE, los DT son el algoritmo que presenta mayor exactitud (accuracy = 0,64); y, en el caso de RandomOverSampler, el algoritmo SVM muestra mayor exactitud (accuracy = 0,59).
Climatic characteristics of winter seasons in the context of climate change (on the example of the Saratov region)
Authors: Zavyalova Elena Vladimirovna , Demakina Irina Igorevna 
Published: December 2024

In the conditions of modern global climate warming, the analysis of its regional manifestations and impact on agriculture in order to adapt the agricultural sphere to them is becoming increasingly important. In recent years, the number of warm winters has been increasingly recorded, accompanied by an increase in winter temperatures, an increase in precipitation, but at the same time, a decrease in the depth of freezing of the soil cover. The article considers the analysis of long-term agrometeorological data, as well as the dynamics of changes in the characteristics of the winter season of the Saratov region for the period 1971-2021 due to the general trend of increasing global and regional air temperatures in recent decades. Studies have found out that the average air temperature of the winter season increased over the period from 2001 to 2021 compared with data for 1971 - 2000 by 1.0?C and began to be -7.1?C. For January and February, such an increase in air temperature reaches 1.1-0.9?C, respectively, for December – 0.5?C. The amount of winter precipitation increased by 9 mm. During the period from 2001 to 2021, the frequency of extremely warm winters increased by 2 times compared to the previous 30-year period of 1971-2000. In modern climatic conditions on the territory of the Saratov region, changes in the characteristics of the winter season are observed.
Association of GPX-1 gene polymorphism with cattle reproduction traits
Authors: Gaynutdinova Elza Ravilevna 
Published: December 2024

Glutathione peroxidase-1 (GPX-1), has a strong antioxidant effect, enzymatically forming the body's antioxidant system, protecting cells from damage during oxidative reactions, reducing hydrogen peroxide to water and lipid hydroperoxide to alcohols, resulting in a decrease in negative effects on the body. The aim of the study was to research the reproductive traits of Holstein cattle with different genotypes of the glutathione peroxidase-1 gene. The study was conducted on 231 cows of the Mukhametshin Z.Z. Peasant Farm Enterprise (PFE) in Sabinsky district of the Republic of Tatarstan. Detection of polymorphism was carried out using the PCR-RFLP method in the Physiology, Biochemistry, Genetics and Animal Nutrition Department of the TatSRIA of FRC KSC RAS. Genotyping showed that the studied population of Holstein cattle is polymorphic in the GPX-1 gene. The frequency of occurrence was as follows: for alleles C – 0.513 and T – 0,487; for genotypes CC – 22.9, TC – 56.7 and TT – 20.3 %. Analysis of the associations of polymorphic variants of the GPX-1 gene with signs of reproductive traits showed that cows that are carriers of the CC genotype of the GPX-1 gene have the best fertile qualities, are characterized by greater live weight at the first insemination - 385.1 kg, and the shortest inter-calving and service periods – 373.4 and 102.3 days respectively, a high coefficient of reproductive capacity (0.98 units) and the Doha index (50.5 units), as well as the yield of live calves per 100 cows – 92.2 heads. The information obtained can be used to improve the reproductive indicators of cattle by including animals of the CC genotype of the GPX-1 gene in animal breeding programs when planning selection events.
Os princípios FAIR e os princípios biblioteconômicos
Authors: Gandra Valquer , Figueiredo Márcia Feijão de 
Published: December 2024

Apresenta os princípios utilizados para tratamento de dados de pesquisa Findable, Acessible, Interoperable e Reusable – FAIR a partir de uma demanda contemporânea que exige não apenas os resultados, mas também os dados de pesquisa. Apresenta o histórico, as diretrizes de cada princípio e dos seus desdobramentos e em seguida a iniciativa GO FAIR, criada por pesquisadores de várias áreas de conhecimento para que os dados de pesquisa sejam tratados a partir dos princípios FAIR. Aponta as relações entre os princípios FAIR e os princípios Biblioteconômicos de processos como a catalogação, classificação, indexação e análise da informação. Ressalta por fim a necessidade de o bibliotecário compreender esses princípios e suas relações com a biblioteconomia para colaborar com a curadoria de dados e para a construção de diretrizes e ferramentas institucionais que implementem o uso.
Metodologia para construção de taxonomias
Authors: Dias Celia da Consolação , Moreiro González José Antonio 
Published: December 2024

Trata-se de um estudo sobre taxonomias aplicadas em diferentes contextos da sociedade com vistas a identificar os elementos da sua estrutura para avaliar a organização dos dados requeridos para a sua construção. O objetivo do artigo é identificar na literatura da Biblioteconomia e Ciência da Informação as metodologias para construção de taxonomias, suas etapas e aplicações, bem como avaliar e refletir sobre esse processo do ponto de vista dos componentes da estrutura. Os procedimentos metodológicos foram: 1) pesquisa bibliográfica com definição de protocolo estruturado de busca, com seleção dos termos no título, resumo e nas palavras-chave; 2) análise de conteúdo e definição de oito categorias estabelecidas a priori; 3) análise das informações do corpus da pesquisa com foco nos elementos da estrutura das taxonomias e da base teórica adotada. Destacam-se estudos com maior nível de detalhamento das etapas e ações, bem como das recomendações propostas pelos autores na execução de cada etapa, com ênfase nas atividades referentes a construção da estrutura das taxonomias. Salienta-se a importância do uso conjunto de procedimentos tecnológicos a partir do estabelecimento de procedimentos operacionais para organizar a construção dos componentes da estrutura da taxonomia.