bluuebunny/crossref_metadata_2025_split huggingface dataset:
Articular Cartilage and Meniscus Risk Factors of Patient-Reported Outcomes 10 Years after ACL Reconstruction: A Multicenter Cohort Study (160)
Authors: Brophy Robert , Huston Laura , Briskin Isaac ,   MOON Knee Group, Spindler Kurt 
Published: October 2021

Objectives: Articular cartilage and meniscal damage are commonly encountered and often treated at the time of anterior cruciate ligament reconstruction (ACLR). Our understanding of how these injuries and their treatment relate to outcomes of ACLR is still evolving. The purpose of this study was to assess whether articular cartilage and meniscal variables are predictive of 10-year outcomes after ACLR. We hypothesized that articular cartilage lesions and meniscus tears/treatment would be predictors of the IKDC, KOOS (all 5 subscales), and Marx activity level at 10-year follow-up after ACLR. Methods: Between 2002 and 2008, 3273 ACLR subjects were prospectively enrolled and followed longitudinally with the IKDC, KOOS, and Marx activity score completed at entry, 2, 6, and 10 years. A logistic regression model was built incorporating variables from patient demographics, surgical technique, articular cartilage injuries, and meniscus tears/treatment to determine the risk factors of IKDC, KOOS, and Marx at 10 years. Results: We completed a minimum follow-up on 77% (2530/3273) of our cohort at 10 years. The cohort was 56% male with a median age of 23 years at the time of enrollment. Incidence of concomitant pathology at the time of surgery consisted of the following: articular cartilage (medial femoral condyle [MFC]-22%, lateral femoral condyle [LFC]-15%, medial tibial plateau [MTP]-4%, lateral tibial plateau [LTP]-11%, patella-18%, trochlear-8%) and meniscal (medial-37%, lateral-46%). Variables that were predictive of 10-year outcomes included articular cartilage damage in the patellofemoral and medial compartments and previous medial meniscus surgery (6% of knees) (Table). Medial and lateral meniscus tears and treatment at the time of ACLR were not associated with 10-year outcomes. Other variables that significantly influenced 10-year outcomes included sex, race, BMI, type of reconstruction (primary vs. revision), baseline outcome scores, and MCL pathology (5.5% of knees). Conclusions: Articular cartilage injury in the patellofemoral and medial compartments at the time of ACLR and a history of medial meniscus surgery prior to ACLR are associated with 10-year ACLR outcomes. However, meniscal tears/treatment at the time of ACLR did not predict 10-year outcomes.
The Incidence of Post-Traumatic Osteoarthritis on Clinical Radiographs at 10 Years after Anterior Cruciate Ligament Reconstruction: Data from the MOON Nested Cohort (168)
Authors: Everhart Joshua , Jones Morgan , Yalcin Sercan , Reinke Emily , Huston Laura ,   MOON Knee Group, Winalski Carl , Spindler Kurt 
Published: October 2021

Objectives: 1) To prospectively determine the incidence of post-traumatic osteoarthritis (PTOA) at 10 years after anterior cruciate ligament reconstruction (ACLR) in young athletic patients on clinical radiographs: and 2) to determine the average difference in clinical radiographic osteoarthritis changes (joint space narrowing [JSN] and osteophyte formation) between the ACLR and contralateral ACL-intact knees. Methods: The first 146 patients in an ongoing prospective nested cohort study within the Multicenter Orthopaedic Outcomes Network (MOON) cohort returned onsite for minimum 10-year follow-up. Inclusion criteria were that patients had a sports-related ACL injury, no prior history of knee surgery, no contralateral ACL injury, and were less than 33 years of age at the time of their ACLR. Bilateral knee standing metatarsophalangeal (MTP) view radiographs were obtained and graded by International Knee Documentation Committee (IKDC), Osteoarthritis Research Society International (OARSI), and modified Kellgren-Lawrence (KL) criteria by two blinded reviewers. Inter-rater reliability was determined for all clinical radiographic OA grading criteria. The incidence and severity of ipsilateral and contralateral knee osteoarthritis were determined among patients without a contralateral ACL injury before 10-year follow-up (n=133). Results: Inter-rater reliability was substantial for IKDC (Gwet’s AC1 = 0.71), moderate for KL (0.48) and almost perfect for OARSI (0.84) grading systems. The 10-year incidence of PTOA on clinical radiographs in the ACLR knee was 43% as defined by osteophytes and 27% as defined by JSN (Table 1). In the contralateral ACL-intact knee, the incidence of osteophyte-defined OA was 10% and JSN-defined OA was 5%. The maximum side-to side difference in medial or lateral compartment OARSI osteophyte grade was 0 in 65% of patients, 1 in 20%, and 2+ in 15% (Figure 1) (Table 2). The maximum difference in OARSI JSN grade was 0 in 77% of patients, 1 in 19%, and 2+ in 4% (Figure 2) (Table 2). Conclusions: In young active patients, the 10-year incidence on clinical radiographs of osteophyte-defined PTOA after ACLR is 43% and JSN-defined PTOA is 27%. The average difference in degree of osteophyte formation (≤1 grade in 85%) and JSN (≤1 grade in 96%) between the ACLR knee and contralateral ACL-intact knee is small.
Tranexamic Acid has no Effect on Post-Operative Hemarthrosis or Pain Control Following ACL Reconstruction Using Bone Patella Tendon Bone Autograft: A Double-Blind Randomized Controlled Double-Blind Trial (169)
Authors: Fried Jordan , Bloom David , Baron Samuel , Hurley Eoghan , Popovic Jovan , Campbell Kirk , Strauss Eric , Jazrawi Laith , Alaia Michael 
Published: October 2021

Objectives: Tranexamic acid (TXA) is a commonly used medication in orthopaedic procedures, reducing perioperative bleeding and need for transfusion. The purpose of this double-blind randomized controlled study was to evaluate if IV TXA for primary anterior cruciate ligament (ACL) reconstruction with bone-patella tendon-bone (BTB) could reduce perioperative blood loss or postoperative intra-articular hemarthrosis without postoperative drains. Methods: A controlled, randomized, double-blinded trial was conducted in 110 patients who underwent ACLR with BTB autograft. Patients were equally randomized to the control and experimental groups. The experimental group received two 1-gram boluses of IV TXA, one prior to tourniquet inflation and one prior to wound closure; the control group did not receive TXA. If a clinically significant hemarthrosis was evident, the knee was aspirated, and the volume of blood (ml) was recorded. Additionally, perioperative blood loss (ml); Visual Analog Scale (VAS) on postoperative days (POD) 1-7 and post-operative weeks (POW) 1, 6 and 12; postoperative opioid consumption POD 1-7; range of motion (ROM) and ability to straight leg raise (SLR) at POW 1, 6, 12; and pre and postoperative thigh circumference ratio (TCR). Results: There was no significant difference in perioperative blood loss between the experimental and control groups (32.5ml v. 35.6ml, p=0.47). The experimental group had 23 knees aspirated; control group had 26 knees aspirated (p=0.56). No significant difference seen in postoperative hemarthrosis volume with IV TXA (26.7ml v. 37.3ml, p=0.12). There was no significant difference in VAS score between the two groups (p=0.15), additionally, there was no difference in postoperative opioid consumption (p=0.33). There was no significant difference in ROM or ability to SLR, or pre- nor post-operative TCR (p > 0.05 for all). Conclusions: IV TXA in patients who undergo ACLR with BTB autograft does not significantly impact perioperative blood loss, postoperative hemarthrosis, or postoperative pain levels. Additionally, no significant differences were seen in early post-operative recovery regarding ROM or quadriceps reactivation.
Allograft Bone Dowel Incorporation to Tibial and Femoral Tunnels in Two–Stage Revision Anterior Cruciate Ligament Reconstruction (173)
Authors: Kew Michelle , Buyukdogan Kadir , Laidlaw Michael , Miller Mark 
Published: October 2021

Objectives: The purpose of this study was to quantitatively evaluate the radiographic outcomes of allograft dowels used as bone grafts in two-stage revision anterior cruciate ligament reconstruction (ACLR). Methods: Prospective review of patients who underwent 2-stage revision ACLR with allograft bone dowels. Inclusion criteria were tibial/femoral tunnel diameter of >14 mm on pre-operative computed tomography (CT), overlapping prior tunnels with new tunnels (Figure 1). Allograft dowels were placed during the first stage and arthroscopic assessment of dowels was performed at the second-stage revision (Figure 2). Quantitative analysis of radiographic incorporation rates was performed with the Union Ratio (UR, Figure 3A) and Occupying Ratio (OR, Figure 3B) on post-operative CT scans. Biopsy specimens were obtained to analyze incorporation. Results: 21 patients were included. Second-stage revision surgeries were performed at 6.5 months (SD, 2.1 months) after first-stage revision. All dowels preserved their integrity without any signs of degradation and complete incorporation at the host bone and graft junction at the second stage procedure. The average diameter of the dowels placed in tibial tunnels were greater than those placed in femoral tunnels (16.1 mm [SD, 2.3 mm] vs 12.4 mm [SD, 1.6 mm]; p = < .05). CT scans were obtained at 121 days (SD, 28 days) after the first-stage. There was no difference between the OR of femoral and tibial tunnels (87.6% [SD, 4.8%] vs 85.7% [SD, 10.1%]; p = .484), however, the UR was significantly higher in femoral tunnels (74% [SD, 10.5%] vs 83%[ SD, 6.2%], p = 0.005). Histological examination revealed osseous incorporation between the host bone and allograft dowel (Figure 4). Conclusions: Allograft bone dowels are a safe graft choice to replenish bone stock in the setting of a staged revision ACL reconstruction and dowels placed in femoral tunnels had a higher healing union ratio. Further studies are warranted to evaluate long-term clinical outcomes in this subset of patients.
Uneven Playing Field: Insurance Status Adversely Affects Children with Tibial Spine Fractures (181)
Authors: Patel Neeraj , Leska Tomasina , Ganley Theodore , Aoyama Julien , Cruz Aristides , Ellis Henry , Fabricant Peter , Green Daniel , Jagodzinski Jason , Johnson Benjamin , Kushare Indranil , Lee R , McKay Scott , Rhodes Jason , Sachleben Brant , Sargent Catherine , Schmale Gregory , Yen Yi-Meng , Mistovich Justin 
Published: October 2021

Objectives: Previous studies have reported disparities in medical and surgical care resulting from demographic factors, including insurance status. Tibial spine fractures are uncommon injuries, which may exacerbate potential disparities in care. The purpose of this study is to assess the impact of insurance status on the treatment of tibial spine fractures in children and adolescents. Methods: We performed a retrospective cohort study of tibial spine fractures treated at 10 institutions between 2000 and 2019. Polytraumas and patients older than 18 years were excluded. Demographic data was collected as was information regarding pre-operative, intra-operative, and post-operative treatment, with attention to delays in management and differences in care. Both surgical and non-surgical fractures were included, but a separate analysis of operative patients was performed subsequently. Univariate analysis was followed by purposeful entry multivariate regression to adjust for confounding factors. Results: Data was collected on a total of 434 subjects with a mean age of 11.7±3.0. Of these, 61.1% had commercial insurance and 38.9% had public insurance. Publicly insured children were more likely to be injured in a motor vehicle accident. Among athletes, those with public insurance were injured more frequently during football while commercially insured patients were more likely to be injured while skiing. When analyzing the overall cohort of surgical and non-surgical fractures in multivariate analysis, those with magnetic resonance imaging (MRI) performed 21 or more days after injury were 5.3 times more likely to have public insurance (95% CI 1.3-21.7, p=0.02). Similar results were found with the 365 patients that required surgery. In this cohort, those with MRI delayed ≥21 days from injury were 4.8 times more likely to have public insurance (95% CI 1.2-19.6, p=0.03). Children that underwent surgery ≥21 days after injury were 2.2 times more likely to have public insurance (95% CI 1.1-4.1, p=0.02). Those that were publicly insured had 2.5 times higher odds of undergoing open surgery rather than arthroscopic (95% CI 1.1-6.1, p=0.04). These children also had 4.5 times lower odds of receiving a continuous passive motion machine (CPM) after surgery (95% CI 1.7-11.7, p=0.002) and were 4.0 times more likely to be immobilized in a cast rather than a brace post-operatively (95% CI 2.0-8.2, p<0.001). Conclusions: Children with public insurance and a tibial spine fracture were more likely to experience delays with MRI and surgical treatment than those with commercial insurance. Additionally, these patients were more likely to undergo open surgery and post-operative casting and less likely to receive a CPM machine.
Biomechanical Comparison of a Prepared Thick Fresh Frozen Irradiated Fascia Lata Allograft to the Native Superior Capsule (212)
Authors: Debellis Nicholas , Manning John , Tibone James , McGarry Michelle , Adamson Gregory , Lee Thay 
Published: October 2021

Objectives: Superior Capsule Reconstruction (SCR) has been described as treatment option for irreparable tears of the superior rotator cuff. Reported outcomes on the success of the surgery have been variable, with graft choice seeming to be one of the most important factors. Fascia Lata (FL) allograft has been proposed as a potential option as it provides adequate graft thickness while avoiding the morbidity of an autograft harvest. The purpose of this study was to compare the biomechanical characteristics of an SCR with FL allograft (FL-SCR) to a native superior capsule in a cadaveric specimen. Methods: Eight cadaver shoulder specimens were used. Each specimen was tested with a custom shoulder system twice. Initial testing was performed after the specimen was dissected of all soft tissue except for the native superior capsule. Subsequent testing was performed after FL-SCR was done. All allografts were fresh frozen and irradiated. Capsule and graft dimensions were recorded before testing. Biomechanical values recorded were cyclic and load to failure for both the native capsule and FL-SCR, and fixation displacement for the SCR-FL construct. A Paired T-test was performed to compare the biomechanical values of the native superior capsule to the FL-SCR. Results: The mean thickness of the NSC was 2.4 ± 0.6 mm and 7.4 ± 1.2mm for the FL graft. The native superior capsule had an average linear stiffness of 94.5 ± 20.4 N/mm, yield load of 386.9 ± 63.6 N, ultimate load of 444.9 ± 67.7 N and energy absorbed of 1418.4 ± 248.8 N-mm. The FL-SCR construct had an average linear stiffness of 28.0 ± 1.6 N/mm, yield load of 123.8 ± 54.3 N, ultimate load of 369.0 ± 43.4 N and energy absorbed of 5021.2 ± 755.1 N-mm. Comparing the two groups there was a statistically significant difference for stiffness (P = 0.013), yield load (P = 0.03) and energy absorbed (P = 0.003). There was no statistically significant difference between ultimate load. The total displacement of the FL-SCR fixation was 5.8 ± 0.6 mm after 1 cycle, 8.5 ± 0.7 mm after 30 cycles, 11.4 ± 1.8 mm at the yield load and 29.5 ± 1.8 mm at the ultimate load. For the failure mode, 8/8 NSC specimens failed at the mid-substance. The FL-SCR, 3/8 specimens failed at the suture tendon interface and 4/8 had medial anchor pull out. Conclusions: Performing SCR with FL allograft in a cadaver model creates a construct that is sufficiently strong enough to withstand normal physiologic loading of the shoulder, although it does not fully re-create the biomechanical characteristics of a native shoulder superior capsule.
A Three-Dimensional Computed Tomography Radiographic Study -- Can We Predict Glenoid Width Based on Glenoid Height? (216)
Authors: Rayes Johnny , Xu Jian , Sparavalo Sara , Ma Jie , Wong Ivan 
Published: October 2021

Objectives: The purpose of this study was to investigate the relationship between glenoid width and other morphologic parameters using three-dimensional (3D) computed tomography (CT) images of native shoulders in hopes of generating a formula to predict glenoid width which will have utility in planning boney shoulder stabilization surgeries. Methods: 102 glenoid images were obtained for patients who underwent contralateral shoulder glenoid reconstruction for anterior shoulder instability between 2012 and 2020. Demographic data was obtained including age, gender and BMI. The subjects were excluded if they had a prior history of ipsilateral shoulder instability, shoulder fractures, or bone tumors. The following glenoid parameters were measured: width (W), height (H), ratio (W/H), anteroposterior (AP) depth, superior-inferior (SI) depth and version. The shape of the glenoid was also classified into pear, inverted comma or oval. Data was analyzed based on gender and age. Simple logistic regression, Kruskal Wallis Rank tests and Fisher Exact tests were performed. Results: There were 71 male and 25 females with a mean age of 39.74 ± 17.88 years. Pear morphotype accounted for most glenoid shapes (46%). The glenoid width was strongly correlated with the height (coefficient = 0.78) and a regression model equation was obtained: W (mm) = 3.4 + 0.68*H (mm). There was also strong correlation with gender (P<0.0001), age (P=0.0384), BMI (P<0.0001), glenoid shape (P=0.0036), height (P=0.0019), AP and SI depths (P<0.0001). Male gender was associated with higher measurement values for all parameters. Older age was significantly correlated with higher glenoid width values in both male and females group. (P=0.0015 and P=0.0104, respectively). Conclusions: The native glenoid width can be easily estimated using solely the glenoid height. This is particularly important for surgical decision making when facing anterior or posterior glenoid defects in patients with shoulder instability.
Is Workload Associated with Internal Impingement in Professional Baseball Players? An Analysis of Days of Rest, Innings Pitched and Batters Faced (221)
Authors: Chalmers Peter , Mcelheny Kathryn , Dangelo John , Ma Kevin , Rowe Dana , Erickson Brandon 
Published: October 2021

Objectives: Determine if workload; as measured by number of days rest between outings, innings pitched, batters faced, and being a starting pitcher; associates with risk for internal impingement in professional baseball pitchers. Methods: All professional baseball pitchers who were diagnosed with internal impingement between 2011-2017 were identified using the major league baseball (MLB) Health and Injury Tracking System (HITS). A separate player usage dataset was used to determine workload. We then compared workload variables between pitcher-games 2, 6, 12, and >12 weeks prior to documented internal impingement and pitcher games from a control group who were never diagnosed with internal impingement. In a paired analysis, we compared the acute workload (2, 6, 12 weeks) prior to injury and the injured pitcher’s workload >12 weeks prior to injury. Results: There were 624 pitchers who suffered from internal impingement in professional baseball. Across all time points, players with more innings pitched per game, more batters faced per game, and fewer days rest in between games were associated with a subsequent internal impingement compared to controls. Pitchers who threw four or more innings per game had a 1.3-fold increase in percent of players with subsequent internal impingement compared to pitchers who threw only one inning per game. Significantly more starting pitchers were diagnosed with internal impingement over multiple time points compared to controls. Conclusions: Greater pitcher workload was associated with increased risk for internal impingement in professional baseball players. Throwing four or more innings per game increase a pitcher’s risk for internal impingement 1.3-fold compared to pitchers who threw one inning per game. Starting pitchers are more likely to sustain a LD/TM tear than control pitchers.
Superior-Labrum Anterior-Posterior Return to Sport Index (SLAP-RSI) Score to Quantify Psychological Readiness to Return to Play (223)
Authors: Colasanti Christopher , Hurley Eoghan , Lorentz Nathan , Markus Danielle , Matache Bogdan , Campbell Kirk , Jazrawi Laith , Strauss Eric 
Published: October 2021

Objectives: Superior-labrum anterior-posterior (SLAP) tears are common among athletic populations and may require surgical treatment. Return to play post-operatively may be complicated by a number of factors, including psychological readiness to return. The purpose of this study was to evaluate the use of the SLAP Return to Sport Index (SLAP-RSI) score to quantify psychological readiness to return to play following operative management of SLAP tears. Methods: A retrospective review of athletes who underwent operative management of SLAP tears with a minimum of 12-month follow-up was performed. Patients were evaluated for their psychological readiness to return to sport using the SLAP-RSI score. The SLAP-RSI score was created by adapting the terms in the Anterior (ACL-RSI score) with terms related to SLAP tears. A SLAP-RSI score > 56 is considered a passing score for being psychologically ready to return to play. Results: The study included 174 athletes who underwent operative management of SLAP tears. Overall, 73.5% percent of patients were able to return to play, and the mean SLAP-RSI score in this cohort was 74.1±20.9, as compared to 46.7±27.7 in those who were unable to return (p<0.0001). Of those who returned, 82.1% passed the SLAP-RSI benchmark of 56, while of those who did not return, 33.3% passed the SLAP-RSI benchmark of 56. Additionally, a significant difference was found in each component of the SLAP-RSI score between the two cohorts (p<0.05). No individual component of the SLAP-RSI score was below 56 in patients who were able to return to play, while none was above 56 in those who were unable to return. Among patients who were unable to return, ones who cited lifestyle reasons had a higher SLAP-RSI score (77.4 ± 21.8) than those who cited residual pain (28.2 ± 15.1) or fear of re-injury (42.6 ± 23.6) (p<0.0001). Conclusions: Following the operative management of SLAP repair, patients that are unable to return to play exhibit poor psychological readiness to return which may be due to residual pain or fear of re-injury.