bluuebunny/crossref_metadata_2025_split huggingface dataset:
Differences in Instructor, Presenter, and Audience Ratings of PechaKucha and Traditional Student Presentations
Authors: Warmuth Kelly A. , Caple Alexandria H. 
Published: March 2021

Background: Recent evidence suggests PechaKucha—a presentation style utilizing simplified visuals, narration, and rigid time constraints—may promote various learning outcomes and instructor goals better than traditional PowerPoint presentations. Objective: The purpose of this study was to test the effectiveness of students’ PechaKucha compared to traditional presentations from multiple perspectives (instructor, presenter, and audience member) using a between-subjects design. Method: Instructors rated students’ PechaKucha ( n = 48) or traditional presentations ( n = 25), and students completed surveys on their experiences as presenters and audience members, as well as their immediate and delayed retention. Results: PechaKucha required significantly less class time, and received higher instructor ratings of appearance, creativity, and overall presentation quality. PechaKucha presenters displayed higher immediate retention of content from their own presentations than did presenters of traditional presentations, but there were no differences in delayed retention or presenter learning outcomes. PechaKucha audience members reported better understanding, as well as higher delayed retention. PechaKucha benefits were shown even when presentations were conducted remotely due to COVID-19. Conclusion: These findings further point to the utility of PechaKucha for promoting student learning outcomes and instructor goals from multiple perspectives. Teaching Implications: Instructors should consider assigning PechaKucha instead of traditional presentations.
Hearing the voices of children diagnosed with a life-threatening or life-limiting illness and their parents’ accounts in a palliative care setting: A qualitative study
Authors: Ciobanu Estera , Preston Nancy 
Published: March 2021

Background: Exploring children’s experiences of a life-threatening or life-limiting diagnosis is essential in offering appropriate care for them. There have been few studies examining these and they are often from the parent’s perspective. Even if adults are frequently unwilling to share information with children, they become aware of their diagnosis and prognosis. The theory of awareness contexts provided a theoretical framework through which it can be understood what children knew about their condition. Aim: To advance the understanding of the experiences of children with a life-threatening or life-limiting condition. Design: A qualitative study using dyadic interviews and thematic analysis. Setting/participants: Ten children between 14 to 17 years old with a life-threatening or life-limiting illness who were supported by a palliative care service in Romania. Interviews were also undertaken with their mothers. Results: Interview data demonstrated that there was a gap in the child’s experience and understanding of their condition compared to their parents. The data produced six major themes: awareness of the illness, death and dying, the spiritual response to illness, the emotional response to illness, striving for normality and independence and coping strategies. The study showed that children can read subtle cues or they may talk with other children to learn about their illness when information is not openly available to them. Conclusions: Children in the study often know more about their condition than their parents realised. Using this understanding, healthcare professionals can advise parents and children about how to communicate with one another which would enable the children to give voice to their thoughts, emotions and experiences.
‘Living in parallel worlds’ – bereaved parents’ experience of family life when a parent with dependent children is at end of life from cancer: A qualitative study
Authors: Semple Cherith J , McCaughan Eilís , Beck Esther R , Hanna Jeffrey R 
Published: March 2021

Background: When a parent of dependent children (<18 years old) is at end of life from cancer, this has a profound impact on the family. Children less prepared for the death of a parent are more susceptive to poorer psychosocial adjustment in later life. There is a lack of understanding from the literature surrounding what support parents require, and how they navigate this end of life experience. Aim: To explore bereaved parents’ experience and needs for families when a parent is at end of life from cancer with dependent children. Design: In-depth, semi-structured qualitative interviews were conducted with 21 bereaved mothers and fathers, identified from the general public, a family support service and hospice. Data were analysed thematically. Results: Parents often live in ‘parallel worlds’ throughout the end of life period. In one world, ‘living in the moment’, cherishing the ordinariness of family life, remaining hopeful treatment will prolong life, whilst adapting as the illness unfolds. The other world presents as ‘intermitted glimpses that death is approaching’, shadowed with painful emotional concerns surrounding their children and the future. At the end, death rapidly approaches, characterised as suddenly ‘falling off the cliff’; placing significant demands on the well-parent. Conclusions: Amidst challenges, clinicians should provide parents with clear information surrounding a poor prognosis, so families can plan and prepare for parental death. There is a need for healthcare professionals to engage, encourage and equip parents, as they prepare their children throughout the end of life experience for the inevitable death of a parent.
Higher Incidence of Radiographic Posttraumatic Osteoarthritis With Transtibial Femoral Tunnel Positioning Compared With Anteromedial Femoral Tunnel Positioning During Anterior Cruciate Ligament Reconstruction: A Systematic Review and Meta-analysis
Authors: Cinque Mark E. , Kunze Kyle N. , Williams Brady T. , Moatshe Gilbert , LaPrade Robert F. , Chahla Jorge 
Published: March 2021

Background: Anteromedial (AM) femoral tunnel positioning in anterior cruciate ligament reconstruction (ACLR) has been reported by some authors to yield superior clinical and functional outcomes compared with the transtibial (TT) approach; however, differences in the subsequent rates of posttraumatic osteoarthritis (PTOA) are not clear. Purpose: To perform a systematic review and meta-analysis of the literature to evaluate the influence of femoral tunnel positioning during primary ACLR on the development of radiographic PTOA. Study Design: Systematic review and Meta-analysis. Methods: The Cochrane Database of Systematic Reviews, the Cochrane Central Register of Controlled Trials, PubMed (1980-2019), and MEDLINE (1980-2019) were queried for all studies describing the development of PTOA after TT or AM ACLR. Data pertaining to patient demographics, ACLR technique, and radiographic PTOA were extracted. A meta-analysis utilizing the DerSimonian-Laird method for random effects was used to compare the weighted proportion of PTOA after ACLR between the TT and AM approaches. Results: There were 16 studies identified for inclusion with a total of 1546 patients. The mean follow-up across all studies was 10.9 years (range, 5.4-17.8 years). The mean follow-up in the AM and TT groups was 10.8 years (range, 5.4-17 years) and 11.4 years (range, 6-17.8 years), respectively. A total of 783 (50.6%) patients underwent TT ACLR. Of these patients, 401 (weighted mean, 49.3%) developed radiographic PTOA. A total of 763 (49.4%) patients underwent AM ACLR. Of these patients, 166 (mean, 21.8%) went on to develop radiographic PTOA. The meta-analysis demonstrated a significantly greater rate of PTOA after ACLR using a TT technique compared with an AM technique overall (49.3% vs 25.4%, respectively; P < .001) and when studies were stratified by 5- to 10-year (53.7% vs 14.2%, respectively; P < .001) and greater than 10-year (45.6% vs 31.2%, respectively; P < .0001) follow-up. Conclusion: TT ACLR was associated with higher overall rates of radiographic PTOA compared with the AM ACLR approach. The rates of radiographic PTOA after ACLR with a TT approach were also significantly higher than using an AM approach when stratified by length of follow-up (5- to 10-year and >10-year follow-up).
Populism and Memory: Legislation of the Past in Poland, Ukraine, and Russia
Authors: Koposov Nikolay 
Published: March 2021

This article belongs to the special cluster “Here to Stay: The Politics of History in Eastern Europe”, guest-edited by Félix Krawatzek & George Soroka. The rise of historical memory, which began in the 1970s and 1980s, has made the past an increasingly important soft-power resource. At its initial stage, the rise of memory contributed to the decay of self-congratulatory national narratives and to the formation of a “cosmopolitan” memory centered on the Holocaust and other crimes against humanity and informed by the notion of state repentance for the wrongdoings of the past. Laws criminalizing the denial of these crimes, which were adopted in “old” continental democracies in the 1980s and 1990s, were a characteristic expression of this democratic culture of memory. However, with the rise of national populism and the formation of the authoritarian or semi-authoritarian regimes in Russia, Turkey, Hungary, and Poland in the 2000s and 2010s, the politics of memory has taken a significantly different turn. National populists are remarkably persistent in whitewashing their countries’ history and using it to promote nationalist mobilization. This process has manifested itself in the formation of new types of memory laws, which shift the blame for historical injustices to other countries (the 1998 Polish, the 2000 Czech, the 2010 Lithuanian, the June 2010 Hungarian, and the 2014 Latvian statutes) and, in some cases, openly protect the memory of the perpetrators of crimes against humanity (the 2005 Turkish, the 2014 Russian, the 2015 Ukrainian, the 2006 and the 2018 Polish enactments). The article examines Russian, Polish, and Ukrainian legislation regarding the past that demonstrates the current linkage between populism and memory.
Remembering a Contentious Past: Resistance and Collaboration in the Former Soviet Union
Authors: Krawatzek Félix 
Published: March 2021

This article is part of the special cluster, “Here to Stay: The Politics of History in Eastern Europe”, guest-edited by Félix Krawatzek & George Soroka. The Western outskirts of the former Soviet Union suffered huge levels of destruction during World War II. It is for this reason that the memories of the war in countries such as Belarus and the Baltics have centered on the local opposition to the Nazi occupiers in an attempt to bring societies together after the war. This article compares how Latvia and Belarus have represented their involvement in World War II over time and undertakes an analysis of how young people today perceive of this aspect of their country’s history. Of particular interest is the extent to which young people are prepared to admit the existence of collaboration and whether a persona of moral authority is able to shift how young people assess the need for critical engagement with history. To that end, the study relies on an original survey generated in early 2019, which also enquired into questions related to historical memory. I argue that young Belarusians are, on average, more prepared to acknowledge collaboration than young people in Latvia and that the involvement of a moral authority shifts assessments of history in a decisive way in Belarus only. The results for Latvia stress in particular the persistent divide relating to the country’s two linguistic communities.
A review on the interfaces of orbital replacement unit: Great efforts for modular spacecraft
Authors: Ren Jie , Kong Ning , Zhuang Yuan , Zhang Jie , Ma Shuai , Wang Bo , Liu Wei 
Published: March 2021

Over the past decades, the development of single spacecraft for outer space exploration requires more complicated design and higher investment. From the modular design ideas of the International Space Station on-orbit service, an interface design for orbital replacement unit (ORU) provides a path to develop modular spacecraft with reduction of design period and cost for satellites. A review on the ORU interfaces has been made in order to summarize the development of grabbing interfaces, mechanical docking interfaces, and multifunctional docking interfaces of ORUs in the recent 30 years. The interface parameters for both grabbing and mechanical docking processes have been summarized and compared based on the design features of ORUs. The characteristics of mechanical, power, data, thermal flow, and fluid interfaces of the ORUs are discussed as well. The future direction, challenges, and applications of the ORU interfaces have been investigated, and advanced technologies such as target recognition and precise measurement and control are suggested for the development of autonomous and intelligent interfaces. This work provides fundamental knowledge and guidelines for the development of ORU interfaces.
NITRATE-CIN Study: Protocol of a Randomized (1:1) Single-Center, UK, Double-Blind Placebo-Controlled Trial Testing the Effect of Inorganic Nitrate on Contrast-Induced Nephropathy in Patients Undergoing Coronary Angiography for Acute Coronary Syndromes
Authors: Beirne Anne-Marie , Mitchelmore Oliver , Palma Susana , Andiapen Mervyn , Rathod Krishnaraj S. , Hammond Victoria , Bellin Anna , Cooper Jackie , Wright Paul , Antoniou Sotiris , Yaqoob Muhammad Magdi , Naci Huseyin , Mathur Anthony , Ahluwalia Amrita , Jones Daniel A. 
Published: March 2021

Background: Contrast-induced nephropathy (CIN), an acute kidney injury resulting from the administration of intravascular iodinated contrast media, is a significant cause of morbidity/mortality following coronary angiographic procedures in high-risk patients. Despite preventative measures intended to mitigate the risk of CIN, there remains a need for novel effective treatments. Evidence suggests that delivery of nitric oxide (NO) through chemical reduction of inorganic nitrate to NO may offer a novel therapeutic strategy to reduce CIN and thus preserve long term renal function. Design: The NITRATE-CIN trial is a single-center, randomized, double-blind placebo-controlled trial, which plans to recruit 640 patients presenting with acute coronary syndromes (ACS) who are at risk of CIN. Patients will be randomized to either inorganic nitrate therapy (capsules containing 12 mmol KNO3) or placebo capsules containing potassium chloride (KCl) daily for 5 days. The primary endpoint is development of CIN using the Kidney Disease Improving Global Outcomes (KDIGO) criteria. A key secondary endpoint is renal function over a 3-month follow-up period. Additional secondary endpoints include serum renal biomarkers (e.g. neutrophil gelatinase-associated lipocalin) at 6 h, 48 h and 3 months following administration of contrast. Cost-effectiveness of inorganic nitrate therapy will also be evaluated. Summary: This study is designed to investigate the hypothesis that inorganic nitrate treatment decreases the rate of CIN as part of semi-emergent coronary angiography for ACS. Inorganic nitrate is a simple and easy to administer intervention that may prove useful in prevention of CIN in at-risk patients undergoing coronary angiographic procedures.
Motor “freezing” with oxaliplatin
Authors: Patel Monica A , McDevitt Rachel L , Sassack Will , Zalupski Mark M 
Published: March 2021

Introduction We report the case of a patient who experienced severe neurological symptoms collectively characterized as being “frozen” following a second oxaliplatin infusion. Case report A 52-year-old woman with metastatic colon cancer developed severe motor slowing, delayed and incomplete grip and dorsiflexion, speech difficulty, visual impairment, leg cramping and tingling after her second infusion of oxaliplatin. She was transferred from the infusion center to the emergency room and admitted to the hospital for further evaluation. Motor, verbal, and ocular symptoms gradually resolved within 24 hours, and she was discharged home without sequela. Management and outcome: Oxaliplatin dose was subsequently lowered and infusion time increased, and she tolerated future treatments without motor, verbal, or ocular disturbance. Discussion In this case report, we describe a rare form of neurological toxicity involving severe motor slowing, slurred speech, and blurry vision secondary to oxaliplatin.
ECG-guided PICC insertion using a new silicon catheter with a conductive tip: A retrospective clinical study
Authors: Yin Yu-Xia , Gao Wei , Feng Sheng-Yu , Wang Deng-Xu , Wan Min , Liu Cheng-Hu , Wang Lu-Ning , Cao Ming-Kun , Zhang Hai-Jun 
Published: March 2021

Objective: Safety and efficacy of ECG-guided PICC insertion using a new silicon catheter with a conductive tip was evaluated in daily practice. Methods: A retrospective study was conducted on 1659 patients who accepted successful tip-conductive PICC placement and clinically followed-up until the catheter removal between January 2018 and April 2019. Baseline of patient characteristics, catheter placement characteristics, date of dressing changes as well as records of catheter-related complications were extracted from a special designed mobile APP. Results: The first-attempt success (success of placing catheter tip to the ideal position by primary indwelling operation) rate of PICC placement was 99.3%. The average duration of PICC placement was 128.7 ± 39.5 days and 1535 patients (92.5%) reached the therapy end-point without any complications and removed the catheter normally. The cumulative rates of total complications were 7.5%, including exit site infection (2.5%), phlebitis (0.9%), DVT (1.0%), catheter malposition (1.1%), catheter breakage (0.1%), and liquid extravasation (1.8%). In multivariable logistic regression analyses, hyperlipidemia, diabetes mellitus, lung cancer, stomach cancer, and lymphoma were significantly associated with increased risk of complications, as the independent risk factors. Conclusions: This retrospective clinical study demonstrates that ECG-guided insertion of a new tip-conductive PICC is associated with a high rate of first-attempt success and low rate of catheter related complications.
Defining breast cancer awareness and identifying barriers to breast cancer awareness for women with an intellectual disability: A review of the literature
Authors: Walsh Susan , O’Mahony Mairin , Hegarty Josephine , Farrell Dawn , Taggart Laurence , Kelly Louise , Sahm Laura , Corrigan Maria , Caples Maria , Martin Anne-Marie , Tabirca Sabin , Corrigan Mark A. , Lehane Elaine 
Published: March 2021

Introduction: Incidence rates for developing breast cancer are similar for women regardless of intellectual ability. However, women with an intellectual disability present with advanced breast cancers, which often have a poor prognosis. Method: A structured narrative review of the literature was performed to explore the concepts of breast awareness and breast cancer awareness and subsequently, identify barriers to breast cancer awareness encountered by women with an intellectual disability. Results: A total of 22 studies involving people with varying levels of intellectual disability informed this review. The barriers to breast cancer awareness encountered by women with an intellectual disability include: lack of their understanding, the role of the carer and literacy issues. Conclusion: Identifying the barriers to breast cancer awareness for women with an intellectual disability will help to facilitate breast cancer awareness which has the potential to result in better long-term outcomes through an early diagnosis of breast cancer.
Association of right ventricular dysfunction and pulmonary hypertension with adverse 30‐day outcomes in COVID‐19 patients
Authors: Wats Karan , Rodriguez Daniel , Prins Kurt W. , Sadiq Adnan , Fogel Joshua , Goldberger Mark , Moskovits Manfred , Tootkaboni Mahsa Pourabdollah , Shani Jacob , Jacob Jessen 
Published: March 2021

BackgroundCardiac manifestations in COVID‐19 are multifactorial and are associated with increased mortality. The clinical utility and prognostic value of echocardiography in COVID‐19 inpatients is not clearly defined. We aim to identify echocardiographic parameters that are associated with 30‐day clinical outcomes secondary to COVID‐19 hospitalization.MethodsThis retrospective cohort study was conducted in a large tertiary hospital in New York City during the COVID‐19 pandemic. It included 214 adult inpatients with a laboratory‐confirmed diagnosis of COVID‐19 by reverse transcriptase polymerase chain reaction assay (RT‐PCR) for SARS‐CoV‐2 on nasopharyngeal swab and had a transthoracic echocardiogram performed during the index hospitalization. Primary outcome was 30‐day all‐cause inpatient mortality. Secondary outcomes were 30‐day utilization of mechanical ventilator support, vasopressors, or renal replacement therapy.ResultsMild right ventricular systolic dysfunction (odds ratio (OR): 3.51, 95% confidence interval (CI): 1.63–7.57, p = 0.001), moderate to severe right ventricular systolic dysfunction (OR: 7.30, 95% CI: 2.20–24.25, p = 0.001), pulmonary hypertension (OR: 5.39, 95% CI: 1.96–14.86, p = 0.001), and moderate to severe tricuspid regurgitation (OR: 3.92, 95% CI: 1.71–9.03, p = 0.001) were each associated with increased odds of 30‐day all‐cause inpatient mortality. Pulmonary hypertension and moderate to severe right ventricular dysfunction were each associated with increased odds of 30‐day utilization of mechanical ventilator support and vasopressors.ConclusionsRight ventricular dysfunction, pulmonary hypertension, and moderate to severe tricuspid regurgitation were associated with increased odds for 30‐day inpatient mortality. This study highlights the importance of echocardiography and its clinical utility and prognostic value for evaluating hospitalized COVID‐19 patients.
Time trends of pulmonary endarterectomy in patients with chronic thromboembolic pulmonary hypertension
Authors: Hobohm Lukas , Keller Karsten , Münzel Thomas , Konstantinides Stavros V. , Lankeit Mareike 
Published: March 2021

Chronic thromboembolic pulmonary hypertension is considered as a rare but severe complication after acute pulmonary embolism and is potentially curable by pulmonary endarterectomy. We aimed to evaluate, over an 11‐year period, time trends of in‐hospital outcomes of pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension patients and to investigate predictors of the in‐hospital course. We analyzed data on the characteristics, comorbidities, treatments, and in‐hospital outcomes for all chronic thromboembolic pulmonary hypertension patients treated with pulmonary endarterectomy in the German nationwide inpatient sample between 2006 and 2016. Overall, 1398 inpatients were included. Annual number of pulmonary endarterectomy increased from 67 in 2006 to 194 in 2016 (P < 0.001), in parallel with a significant decrease of in‐hospital mortality (10.9% in 2008 to 1.5% in 2016; P < 0.001). Patients’ characteristics shifted slightly toward older age and higher prevalence of chronic renal insufficiency and obesity over time, whereas duration of hospital stay decreased over time. Independent predictors of in‐hospital mortality were age (OR 1.03 (95%CI: 1.01–1.05); P = 0.001), right heart failure (2.55 (1.37–4.76); P = 0.003), in‐hospital complications such as ischemic stroke (6.87 (1.06–44.70); P = 0.044) and bleeding events like hemopneumothorax (24.93 (6.18–100.57); P < 0.001). Annual pulmonary endarterectomy volumes per center below 10 annual procedures were associated with higher rates of adverse in‐hospital outcomes. Annual numbers of chronic thromboembolic pulmonary hypertension patients treated with pulmonary endarterectomy increased markedly in Germany between 2006 and 2016, in parallel with a decrease of in‐hospital mortality. Our findings suggest that perioperative management of pulmonary endarterectomy, institutional experience, and patient selection is crucial and has improved over time.