bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kewenangan Pusat Penelitian dan Analisis Transaksi Keuangan (PPATK) dalam Menerobos Rahasia Bank berdasarkan Undang-Undang Nomor 8 Tahun 2010 tentang Tindak Pidana Pencucian Uang
Authors: Iriansyah  , Irfansyah  , Febrina Rezmia 
Published: November 2021

Bagaimanakah kewenangan PPATK menerobos rahasia Bank menurut UU Nomor pelaksanaan Peraturan Kepala Kepolisian Negara Republik 8 Tahun 2010 tentang tindak pidana pencucian uang. Metode penelitian ini dilakukan secara langsung dilapangan sesuai dengan jenisnya penelitian hukum normatif. Hasil penelitian diketahui bahwa pelaksanaan regulasi tentang Di dalam Undang-undang tersebut peranan PPATK adalah pencegahan dan pemberantasan tindak pidana pencucian uang, pengelolaan data dan informasi yang diperoleh PPATK, pengawasan terhadap kepatuhan pihak pelapor dan analisis atau pemeriksaan laporan dan informasi transaksi keuangan yang berindikasi tindak pidana pencucian uang dan atau tindak pidana lain. Undang-Undang Nomor 10 Tahun 1998 tentang Perbankan menyangkut yang mengatur tentang kerahasian Bank khususnya seluruh data dan informasi, dengan adanya kewenangan PPATK sebagaimana diatur dalam Undang_undang Nomor 8 Tahun 2010, kerahasian bank menjadi tidak berarti
Tanggung Jawab Hukum Perusahaan Asuransi Jiwa terhadap Tertanggung dalam Pembayaran Klaim Asuransi
Authors: Afrita Indra , Arifalina Wilda 
Published: November 2021

Bagaimana Tanggung Jawab Hukum Perusahaan Asuransi Jiwa terhadap Tertanggung dalam Pembayaran Klaim Asuransi. Jenis penelitian yang dilakukan adalah hukum normatif merupakan penelitian kepustakaan yang datanya diperoleh dari mengkaji bahan-bahan pustaka. Hasil dan pembahasan dari penelitian adalah Tanggung jawab hukum perusahaan asuransi jiwa terhadap tertanggung dalam pembayaran klaim asuransi dimana perjanjian asuransi jiwa yang disebut dengan polis berlaku apabila telah ditutup (telah ada persesuaian kehendak) berdasarkan ketentuan tersebut pembayaran uang santunan kepada pemegang polis atau tertunjuk wajib dilaksanakan oleh penanggung apabila telah terjadi evenemen atau resiko. Penyelesaian hukum yang dilakukan oleh perusahaan asuransi jiwa terhadap tertanggung dalam pembayaran klaim asuransi dalam hal kepailitan Perusahaan Asuransi, jaminan perlindungan terhadap pemegang polis asuransi telah diatur secara tegas pemegang polis mendapatkan pelunasan terlebih dahulu dari pada kreditur lainnya
Penegakan Hukum Perdagangan Perempuan (Trafficking In Women) Diwilayah Hukum Pengadilan Negeri Pekanbaru
Authors: Yusuf M Fadly daeng 
Published: November 2021

Terdapat beberapa kendala yang menyebabkan tindak pidana perdagangan perempuan masih terus saja terjadi, yaitu diakibatkan krisis ekonomi dan krisis moral rendahnya sanksi pidana,.Sebagai lembaga penegak hukum adalah Pengadilan Negeri Pekanbaru berfungsi untuk memeriksa, memutus, dan menyelesaikan perkara salah satunya perkara pidana untuk rakyat pencari keadilan di Wilayah Pekanbaru).Penelitian ini tentang Penegakan hukum perdagangan perempuan (Trafficking in women) diwilayah Pengadilan negeri Pekanbaru terdiri dari dua masalah pokok yaitu : 1.Bagaimana penegakan hukum tindak pidana perdagangan perempuan (trafficking in women) di wilayah Pengadilan Negeri Pekanbaru?, Bagaimana prosedur penyelesaian dalam penegakan hukum perdagangan perempuan (trafficking in women) di wilayah Pengadilan Negeri Pekanbaru?Untuk mendukung penelitian tersebut,penulis menggunakan metodelogi penelitian Hukum yuridis normatif dan Sosiologis dimana penelitian untuk melihat korelasi antara hukum dengan masyarakat yang terjadi dalam putusan di Pengadilan Negeri Pekanbaru. Sumber data berasal dari data primer yaitu berkas perkara,UU PTTPO,KUHP,KUHAP.
Ophthalmic Manifestations of ANCA-Associated Vasculitis
Authors: İnanç Tekin Merve , Çakar Özdal Müge Pınar 
Published: November 2021

Ocular manifestations in antineutrophil cytoplasmic antibody-associated vasculitis can be associated with the general or limited form of disease and can even occur in the absence of systemic disease. Ocular manifestations of associated vasculitis can be the first symptom of previously not manifested or undiagnosed systemic disease, allowing ophthalmologists to contribute to the diagnosis. Although its ocular findings are variable and nonspecific, the presence of necrotizing changes and peripheral corneal involvement accompanying scleral inflammation are important clues suggesting systemic vasculitis, especially associated vasculitis. The disease may affect all layers of the eye; scleritis and orbital involvement being the most common. Conjunctivitis, episcleritis, peripheral ulcerative keratitis, uveitis and retinal vasculitis are other ocular findings that may be observed during the disease course.
Ocular involvement is most commonly seen in granulomatosis with polyangiitis followed by eosinophilic granulomatosis with polyangiitis and microscopic polyangiitis. Due to the high morbidity and mortality of associated vasculitis, it is very important to recognize the ocular manifestations of vasculitis as a sign of the underlying systemic disease and an indicator for the disease activity. Treatment varies depending on the location and severity of the ocular involvement. Although localized medical and surgical treatments can help to manage associated ocular disease, systemic immunosuppressive medications are often required to control the underlying disease. With the increasing availability and use of biological agents, prognosis has improved in patients with severe ocular complications. Rituximab appears to be useful in inducing remission and controlling relapses in patients with ocular involvement of associated vasculitis, particularly in cyclophosphamide resistant cases. A multidisciplinary approach in the diagnosis, treatment and follow-up of patients with associated vasculitis is required in order to achieve successful results.
Hasil Luaran Bayi Pada Ibu Hamil Yang Mengalami Preeklampsia
Authors: Zamaun Nurlana , Dewi Anna Sari , Syamsu Rachmat Faisal , Mappaware Nasrudin Andi , Arfah Arni Isnaini 
Published: November 2021

Preeklampsia adalah sindrom klinis pada masa kehamilan setelah kehamilan 20 minggu yang ditandai dengan peningkatan tekanan darah >140/90 mmHg. Faktor resiko terjadinya preeklamsia adalah usia, nulliparitas, riwayat preeklamsia sebelumnya, riwayat penyakit hipertensi dan diabetes melitus, riwayat keluarga dan obesitas. Beberapa teori mengemukakan tentang bagaimana terjadinya preeklampsia antara lain teori genetik, teori iskemia uteroplasenter, teori kerusakan endotel pembuluh darah. Tujuan dari literature review ini bertujuan untuk mengetahui hasil luaran bayi pada ibu yang mengalami preeklampsia. Jenis penelitian ini menggunakan literature review dengan desain narrative review yaitu mencari artikel yang membahas tentang hasil luaran bayi pada ibu yang mengalami preeklampsia yang telah dipublikasikan pada jurnal dari tahun 2017-2020. Jurnal dipilih berdasarkan kriteria inklusi dan eksklusi yang telah ditetapkan sebelumnya. Berdasarkan telaah dari beberapa jurnal, didapatkan hasil luaran bayi pada ibu yang mengalami preeklampsia adalah bayi kurang bulan kecil masa kehamilan (KMK), bayi kurang bulan sesuai masa kehamilan (SMK), dan asfiksia.
Perbandingan Tingkat Stres Mahasiswa Tahap Akademik FK UMI Angkatan 2017, 2018 Dan 2019
Authors: Kurniawan Dedy , Mokhtar Shulhana , Rasfayana Rasfayana , Sodiqah Yani , Arifin Arina Fathiyyah 
Published: November 2021

Stres adalah kondisi yang disebabkan oleh interaksi antara individu dengan lingkungan yang menimbulkan persepsi jarak antara tuntutan-tuntutan yang berasal dari situasi yang bersumber pada sistem biologis, psikologis dan sosial dari seseorang. Mahasiswa yang mengalami stres membutuhkan perhatian serius karena dapat membawa dampak yang kurang baik terhadap proses pembelajaran dan prestasi mahasiswa. Berbagai penelitian telah mendokumentasikan stres di kalangan mahasiswa kedokteran dan menunjukkan adanya stres yang sangat tinggi apabila dibandingkan dengan program studi lain di sektor non-medis. Tujuan dari penelitian ini yaitu untuk mengetahui perbandingan tingkat stres mahasiswa tahap akademik Fakultas Kedokteran UMI angkatan 2017, 2018 dan 2019.
Análisis del ciclo PHVA en la gestión de proyectos, una revisión documental
Authors: Moyano-Hernández Faber Andres , Villamil Sandoval Diana Carolina 
Published: November 2021

El ciclo PHVA ha sido utilizado ampliamente para la mejora de los procesos; por ello, es adecuado pensar que es una herramienta útil para la gestión de proyectos. El objeto de la presente investigación es evidenciar los principales aportes que han realizado diferentes autores en la implementación del ciclo PHVA para la mejora continua en la gestión de proyectos. Se realizó una revisión documental, empleando estrategias de búsqueda con palabras clave en Scopus y ScienceDirect. Se recopilaron documentos de los últimos 5 años, resultando un total de 186 artículos. Al verificar la pertinencia con el tema de estudio, la lista se redujo a 21. Se destacan como resultados la vigencia temática del ciclo PHVA, la variabilidad de sectores empresariales y los países que la implementan y estudian. El continente europeo lidera el volumen de publicaciones y a pesar de encontrar alto volumen de artículos, muchos se descartaron por debilidades metodológicas.
The PDCA cycle has been widely used for process improvement; therefore, it is appropriate to think that it is a useful tool for project management. The purpose of this research is to show the main contributions that different authors have made in the implementation of the PDCA cycle for continuous improvement in project management. A documentary review was carried out, using search strategies with keywords in Scopus and Science Direct. Documents from the last 5 years were collected, resulting in a total of 186 articles. When verifying the relevance to the subject of study, the list was reduced to 21. The thematic validity of the PDCA cycle, the variability of business sectors and the countries that implement and study it stand out as results. The European continent leads the volume of publications and despite finding a high volume of articles, many were discarded due to methodological weaknesses.
Revisión de electroencefalografía portable y su aplicabilidad en neurociencias.
Authors: Rios-Arismendy Sara , Ochoa-Gómez John Fredy , Serna-Rojas Carolina 
Published: November 2021

La electroencefalografía (EEG) es una técnica que permite registrar la actividad eléctrica del cerebro y ha sido estudiada durante los últimos cien años en diferentes ámbitos de la neurociencia. En los últimos años se ha investigado y desarrollado equipos de medición que sean portables y que permitan una buena calidad de la señal, por lo cual se realizó una revisión bibliográfica de las compañías fabricantes de algunos dispositivos de electroencefalografía portable disponibles en el mercado, se exponen sus características principales, algunos trabajos encontrados que fueron realizados con los dispositivos, comparaciones entre los mismos y una discusión acerca de las ventajas y desventajas de sus características. Finalmente se concluye que a la hora de comprar un dispositivo para electroencefalografía portable es necesario tener en cuenta el uso que se le va a dar y el costo-beneficio que tiene el equipo de acuerdo con sus características.
Encephalography is a technique that allows the recording of electrical activity of the brain and has been studied during the last hundred years in different areas of neuroscience. For several years, measuring equipment that are portable and that allow a good signal quality to have been researched and developed, so a literature review of the manufacturing companies of some of portable electroencephalography devices available on the market was carried out: Its main features are exposed, as well as some of the work found that were made with those, comparisons between them and a discussion about the advantages and disadvantages of their features. It is concluded that, when a portable encephalography device is bought, it’s necessary to take into consideration the use that it will be having and the cost-benefit that the device has according to its features.
Monitoring Program Keluarga Harapan Berbasis Mobile GIS Menggunakan K-Means Clustering
Authors: Muhariya Ahmad , Widada Bebas , Siswanti Sri 
Published: November 2021

Poverty is a condition that is below the line of minimum requirement standard values, both for food and non-food. The Government of Indonesia has various programs to overcome poverty-based assistance social, including the family hope program. This family hope program is the provision of conditional cash assistance to very poor households in which there are pregnant women, toddlers, elementary, junior high, high school, elderly, and severe disabilities. The amount of assistance obtained based on the level of family poverty with poverty level parameters is seen from the many categories of very poor households concerned along with the obligation of participants to carry out important commitments in the field of Health and Education. The purpose of this research is the development of a mobile-based poor family monitoring application using the k-means clustering method. Validity test results using sample data 21, it can be concluded that the system can group poor families into 7 clusters with a thoroughness rate of 90.4%. Based on these results, K-Means Clustering can be said to have a high accuracy value for clustering poor families.
Relationship Between Leaflets and Root in Normal Aortic Valve Based on Computed Tomography Imaging: Implication for Aortic Valve Repair
Authors: Yang Tianyang , Wen Haini , El-Hamamsy Ismail , Ni Qiming , Sun Yanbin , Zhu Dan 
Published: November 2021

Objective: By assessing the normal dimensions and the relationship between the aortic root and leaflets in Chinese population, the objective of this three-dimensional computed tomography (3DCT)-based study was to establish a matching reference for leaflets and aortic root for aortic valve (AV) repair.Method: Electrocardiogram-gated multi-detector CT was performed on 168 Chinese participants with a normal aortic valve. Measurements of the aortic annuli and leaflets were obtained. The correlations between and the ratios of the specific root and leaflet measurements were analyzed. The references for the leaflet and root dimensions were suggested based on geometric height (gH) using a linear regression equation. The utility of the ratios was tested with CT images of 15 patients who underwent aortic valve repair.Result: The mean annulus diameter (AD), sino-tubular junction (STJ) diameter, geometric height (gH), effective height (eH), free margin length (FML), commissural height (ComH), inter-commissural distance (ICD), and coaptation height (CH) were 22.4 ± 1.7 mm, 27.3 ± 2, 0.4 mm, 15.5 ± 1.7 mm, 8.9 ± 1.2 mm, 32.0 ± 3.4 mm, 17.9 ± 1.9 mm, 23.1 ± 2.3 mm, and 3.1 ± 0.6 mm, respectively. The gH/AD, FML/ICD, and eH/ComH ratios were 0.69 ± 0.07, 1.38 ± 0.08, and 0.50 ± 0.07, respectively. The gH correlated with all other leaflet and root measurements (P &lt; 0.01), whereas the FML demonstrated a better correlation with ICD compared with gH (R2 = 0.75, and R2 = 0.37, respectively). The FML/ICD and eH/ComH ratios might be used to assess leaflet-root mismatch and post-repair leaflet billowing.Conclusion: The normal aortic valve measurements based on 3DCT revealed a specific relationship between the root and leaflets; and this will guide the development of an objective method of aortic valve repair.
Experience, Seniority and Gut Feeling—A Qualitative Examination of How Swedish Police Officers Perceive They Value, Evaluate and Manage Knowledge When Making Decisions
Authors: Eliasson Michelle 
Published: November 2021

There is a debate in current scholarship regarding whether or not education and training is an effective tool to change police officers’ conduct. Compared to the United States, Sweden has longer training for officers who experience 2 years of academic training and 6 months of practical training. The Swedish police training is also, contrary to the American training, standardized. This paper aims to investigate how Swedish officers value, evaluate and manage knowledge when making decisions. To examine this further 27 qualitative interviews were conducted with 14 male and 13 female Swedish police officers during 2018. The interviews were analyzed using inductive thematic analysis in both English and Swedish to uncover themes and codes. Findings suggest that police officers utilize experience, seniority, and gut feeling when valuing, evaluating and managing knowledge. Furthermore, the results imply that certain types of knowledge are valued differently by officers. These findings can inform how and if education can be used as a tool to potentially change how officers in the US and other countries make their decisions.
Clinical and Genetic Characteristics of Chinese Children With GLUT1 Deficiency Syndrome: Case Report and Literature Review
Authors: Hu Qingqing , Shen Yuechi , Su Tangfeng , Liu Yan , Xu Sanqing 
Published: November 2021

Objective: GLUT1 deficiency syndrome (GLUT1-DS) is a rare, treatable neurometabolic disorder. However, its diagnosis may be challenging due to the various and evolving phenotypes. Here we report the first Chinese familial cases with genetically confirmed GLUT1-DS and analyze the characteristics of Chinese children with GLUT1-DS from clinical, laboratory, and genetic aspects.Methods: We reported a Chinese family with three members affected with GLUT1-DS and searched for relevant articles up to September 2020 from PubMed, WOS, CNKI, and WanFang databases. A total of 30 Chinese patients diagnosed with GLUT1-DS (three newly identified patients in one family and 27 previously reported ones) were included and analyzed in this study.Results: The median age of onset of the 30 patients (male: 18, female: 12) was 8.5 months (range, 33 days to 10 years). Epileptic seizures were found in 25 patients, most with generalized tonic–clonic and focal ones. Movement disorders were found in 20 patients—frequently with ataxia and dystonia, developmental delay in 25 patients, and microcephaly only in six patients. The cerebrospinal fluid (CSF) analysis showed decreased CSF glucose (median: 1.63 mmol/L, range: 1.1–2.6 mmol/L) and glucose ratio of CSF to blood (median: 0.340; range: 0.215–0.484). The genetic testing performed in 28 patients revealed 27 cases with pathogenic variations of the SLC2A1 gene, including 10 missense, nine frameshift, three nonsense, three large fragment deletions, and two splice-site mutations. Most patients had a good response to the treatment of ketogenic diet or regular diet with increased frequency. Although three patients in this Chinese family carried the same pathogenic mutation c.73C &gt; T (p.Q25X) in the SLC2A1 gene, their symptoms and responses to treatment were not exactly the same.Conclusion: The clinical manifestations of GLUT1-DS are heterogeneous, even among family members sharing the same mutation. For children with unexplained epileptic seizures, developmental delay, and complex movement disorders, detection of low CSF glucose or SLC2A1 gene mutations is helpful for the diagnosis of GLUT1-DS. Early initiation of ketogenic diet treatment significantly improves the symptoms and prognosis of GLUT1-DS.
Lumpfish (Cyclopterus lumpus) Is Susceptible to Renibacterium salmoninarum Infection and Induces Cell-Mediated Immunity in the Chronic Stage
Authors: Gnanagobal Hajarooba , Cao Trung , Hossain Ahmed , Dang My , Hall Jennifer R. , Kumar Surendra , Van Cuong Doan , Boyce Danny , Santander Javier 
Published: November 2021

Renibacterium salmoninarum is a Gram-positive, intracellular pathogen that causes Bacterial Kidney Disease (BKD) in several fish species in freshwater and seawater. Lumpfish (Cyclopterus lumpus) is utilized as a cleaner fish to biocontrol sea lice infestation in Atlantic salmon (Salmo salar) farms. Atlantic salmon is susceptible to R. salmoninarum, and it can transfer the infection to other fish species. Although BKD outbreaks have not been reported in lumpfish, its susceptibility and immune response to R. salmoninarum is unknown. In this study, we evaluated the susceptibility and immune response of lumpfish to R. salmoninarum infection. Groups of lumpfish were intraperitoneally (i.p.) injected with either R. salmoninarum (1×107, 1×108, or 1×109 cells dose-1) or PBS (control). R. salmoninarum infection kinetics and mortality were followed for 98 days post-infection (dpi). Transcript expression levels of 33 immune-relevant genes were measured in head kidney (n = 6) of fish infected with 1×109 cells/dose and compared to the control at 28 and 98 dpi. Infected lumpfish displayed characteristic clinical signs of BKD. Lumpfish infected with high, medium, and low doses had a survival rate of 65%, 93%, and 95%, respectively. Mortality in the high-dose infected group stabilized after 50 dpi, but R. salmoninarum persisted in the fish tissues until 98 dpi. Cytokines (il1β, il8a, il8b), pattern recognition receptors (tlr5a), interferon-induced effectors (rsad2, mxa, mxb, mxc), and iron regulation (hamp) and acute phase reactant (saa5) related genes were up-regulated at 28 dpi. In contrast, cell-mediated adaptive immunity-related genes (cd4a, cd4b, ly6g6f, cd8a, cd74) were down-regulated at 28 dpi, revealing the immune suppressive nature of R. salmoninarum. However, significant upregulation of cd74 at 98 dpi suggests induction of cell-mediated immune response. This study showed that R. salmoninarum infected lumpfish in a similar fashion to salmonid fish species and caused a chronic infection, enhancing cell-mediated adaptive immune response.
N6-Methyladenosine Methylation Analysis of Long Noncoding RNAs and mRNAs in IPEC-J2 Cells Treated With Clostridium perfringens beta2 Toxin
Authors: Yang Jiaojiao , Yang Qiaoli , Zhang Juanli , Gao Xiaoli , Luo Ruirui , Xie Kaihui , Wang Wei , Li Jie , Huang Xiaoyu , Yan Zunqiang , Wang Pengfei , Gun Shuangbao 
Published: November 2021

BackgroundThe n6-methyladenosine (m6A) modification is present widely in mRNAs and long non-coding RNAs (lncRNAs), and is related to the occurrence and development of certain diseases. However, the role of m6A methylation in Clostridium perfringens type C infectious diarrhea remains unclear.MethodsHere, we treated intestinal porcine jejunum epithelial cells (IPEC-J2 cells) with Clostridium perfringens beta2 (CPB2) toxin to construct an in vitro model of Clostridium perfringens type C (C. perfringens type C) infectious diarrhea, and then used methylated RNA immunoprecipitation sequencing (MeRIP-seq) and RNA sequencing (RNA-seq) to identify the methylation profiles of mRNAs and lncRNAs in IPEC-J2 cells.ResultsWe identified 6,413 peaks, representing 5,825 m6A-modified mRNAs and 433 modified lncRNAs, of which 4,356 m6A modified mRNAs and 221 m6A modified lncRNAs were significantly differential expressed between the control group and CPB2 group. The motif GGACU was enriched significantly in both the control group and the CPB2 group. Gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) annotation analysis showed that the differentially methylated modified mRNAs were mainly enriched in Hippo signaling pathway and Wnt signaling pathway. In addition, the target genes of the differentially m6A modified lncRNAs were related to defense response to virus and immune response. For example, ENSSSCG00000042575, ENSSSCG00000048701 and ENSSSCG00000048785 might regulate the defense response to virus, immune and inflammatory response to resist the harmful effects of viruses on cells.ConclusionIn summary, this study established the m6A transcription profile of mRNAs and lncRNAs in IPEC-J2 cells treated by CPB2 toxin. Further analysis showed that m6A-modified RNAs were related to defense against viruses and immune response after CPB2 toxin treatment of the cells. Threem6A-modified lncRNAs, ENSSSCG00000042575, ENSSSCG00000048785 and ENSSSCG00000048701, were most likely to play a key role in CPB2 toxin-treated IPEC-J2 cells. The results provide a theoretical basis for further research on the role of m6A modification in piglet diarrhea.