bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efficacy and safety of short course
adjuvant trastuzumab combination chemotherapy in
breast cancer
Authors: Hingmire Sachin S. , Sambhus Mahesh B. , Kelkar Dhananjay S. , Joshi Sujit , Parikh Purvish M. , Bharath R. 
Published: January 2021

Abstract
Background: The adjuvant short course
9-week trastuzumab combination therapy for human
epidermal receptor 2 positive breast cancer
patients may often be considered as a
cost-effective and safe option and has important
implications for the Indian subcontinent as well
as other developing countries. However, such
regimens of shorter duration trastuzumab therapy
like FinHer, offered in view of economic
constraints, may not be able to achieve globally
comparable cure rates in early breast cancer
especially with high-risk women with more than 3
lymph node positive. Methods and Material: Outcome
of 21 patients with HER2 positive breast cancer
was treated with short course trastuzumab
combination chemotherapy in the adjuvant setting
was studied. Results: Out of 21 patients 15 are
alive and disease free with a follow up of up to
73 months (median follow up 42 months).
FACTORS AFFECTING THE BUYING DECISION FOR B’LAO SILK
Authors: QUANG BÙI VĂN 
Published: January 2021

The developeding economic environment leads to consumers‟ changes in choosing silk types. However, consumers' comparison between traditional silk with high cost and industrial silk at low prices is unclear. This research aims to explore the factors that influence to choose the B‟Lao silk to provide enterprises with appropriate production and business orientations. The study was conducted through a survey of 226 consumers who have used B‟Lao silk at supermarkets and shops. Analysis of research results through PLS-SEM model with Smart PLS. The results showed that affecting factors to choose B‟Lao silk selection from high to low: marketing, influence group, psychology, information and brand. The research results enable businesses to increase consumer‟s choice of B‟Lao silk.
Thyrotoxicosis. Clinical guidelines for diagnosis and treatment. Part ІІ
Authors: Pidchenko N. S. , Vasylyev L. Ya. , Grushka G. V. , Astapieva O. M. , Savchenko A. S. 
Published: January 2021

Background. Recently they have reported an increased rate of thyrotoxicosis, which is characterized by polyetiology, a variety of clinical manifestations and potential treatment. Appropriate treatment requires an accurate diagnosis and depends on the comorbidities and preferences of the patient.
Purpose. To highlight the key points of clinical guidelines for diagnosis and treatment of thyrotpxicosis provided by the American Thyroid Association and the American Association of Clinical Endocrinologists, US Endocrine Society dealing with diagnosis and treatment of thyroid diseases as well as the local clinical protocols of SO «Grigoriev Institute for Medical Radiology and Oncology of the National Academy of Medical Sciences of Ukraine».
Materials and methods. Based on the search of contributions in the electronic databases over the last 5 years, which are included in the Cochrane Library, PUBMED and MEDLINE databases. Clinical guidelines are based on expert consensus and assessing the significance according to the international guidelines for thyrotoxicosis.
Results and discussion. The paper deals with up-to-date guidelines on diagnosis, management and treatment of patients with different forms of thyrotoxicosis. It presents a detailed strategy for those patients depending on etiology of the disease. The therapeutic approaches to treating Graves’ disease, autoimmune ophthalmopathy, thyrotoxic crisis, gravidae as well as the peculiarities of treating patients with subclinical hyperthyroidism and iodine-induced thyrotoxicosis have been substantiated.
Conclusions. The treatment of thyrotoxicosis remains a challenging issue of modern internal medicine. Despite the existing numerous clinically proven protocols for the treatment of this pathology, the comorbid background of patients complicates following them. The implementation of the provided protocol elements will make it possible to introduce the principles of a customized approach in thyrotoxicosis patients.
To the centenary of Radiology and Radiation Medicine Department of O. O. Bogomolets National Medical University
Authors: Tkachenko M. М. 
Published: January 2021

Purpose – to summarize historical data on the formation and development of Radiology Department of O. O. Bogomolets National Medical University.
Materials and methods. The paper deals with the analysis of pupblicly available literature sources and archival data concerming the history of Radiology Department, establishing scientific school of development of methodological approaches to teaching Radiology at the university.
Results and discussion. Over the century of its existence, Radiology and Radiation Medicine Department of O. O. Bogomolets National Medical University along with the staff members, including different generations of teachers, scientists and physicians, have been focused to present key directions and priorities in diagnostic radiology, radiation therapy and radiation medicine in the educational process, research and clinical activities and make those be significantly in line with the trends of radiological research development in the world.
Conclusions. The department is the basic one among the radiology departments of medical universities in Ukraine; it is in charge of teaching and learning activities as well as management of radiological service in the country. Domestic radiology and radiation medicine have always been distinguished by a combination of own glorious traditions in the development of diagnostic radiology issues and therapy striving to follow in the footsteps of world scientific, clinical and diagnostic thought.
Tudatos táplálkozás, avagy mit is tudunk a halról?
Authors: Rusznák Dóra 
Published: January 2021

Az év végétől hatályos 1169/2011/EU Európai Uniós rendelet új kérdéseket vet fel a fogyasztók élelmiszerekkel kapcsolatos tájékoztatásával kapcsolatban. A vonatkozó előírások számos tekintetben szigorodnak és a korábbinál részletesebb tájékoztatást írnak elő. A nem feldolgozot élelmiszerek azonban továbbra ismentesülnek a tápértékjelölés alól, így például a halakban a takarmányozás során felhalmozódot különböző segédanyagokról már nem értesülhet a fogyasztó.
számviteli szolgáltatók felelőssége
Authors: Hegedűs Mihály 
Published: January 2021

A stagnáló gazdaság kiútkeresésének időszakában háttérbe szorul az etikus gazdasági magatartás, növekszik a csalások száma, a meg nem engedet , kreatív eszközök igénybevétele. Az egyes pályázatok mellékleteihez beadott pénzügyi tervek, egyszerűsítet éves beszámolók elemzése, ellenőrzése, a napi sajtó hírei a számviteli értékelési eljárások, az egyes adótörvények megsértését támasztják alá. A költségvetési csalás okai a kiútkeresési, megélhetési, törvényi motivációkkal kerülnek összefüggésbe, míg más okok a vállalkozás minél jobb piaci megítélésére, a hitelek kölcsönök felvétele kapcsán támasztot követelmények teljesítésére vezethetők vissza. Az ellenőrzési rendszerek tagoltsága, a kontrollkörnyezet hiánya, a könyvvizsgálai kötelezettség eltörlése, az értékhatár felemelése, a gyakori adótörvényi változások, a feltárás valószínűsége, az ellenmondó ítéletek, a kockázat nélküli csalások elkövethetőségét támogatja. A csalások elkövetésének megakadályozására szükséges lenne a társadalom által is elvárt etikai szabályok, csalásellenes irányelvek megfogalmazása, oktatása, betartatása, a hatékony ellenőrzési rendszer működtetése. A társaságok tulajdonosainak, menezsdmentjének, az államiszervezeteknek, és a számviteli szolgáltatóknak az etikai szabályok megtartása mellett kellene teljes elkötelezettséggel működnie, mert csak így szerezhető meg a közhiteles beszámolók valódiságában, valamint az állam működésében vetett feltétlen bizalom. Az etika, bizalom és az adómorál, a korrupció jelenléte és mértéke egymással összefüggő, egymásra ható fogalmak. Az állam intézményrendszerének kiépítése, megfelelő működtetése, a számviteli szolgáltatók felelőssége , hogy alapos, több szakterületet érintő szakmai tudásukkal, etikus magatartásukkal, ellenőrzésükkel ne adjanak lehetőséget a vállalkozások szereplőinek arra, hogy a gazdasági tevékenységük során nem a vállalkozás érdekében felmerülő költségeiket a könyveikben rögzítsék, vagy a korrupció eszközeit is igénybe vegyék működésükhöz. A bizalom, etika és adómorál megközelítései számos aspektusból indulhatnak ki, dolgozatom egy lehetséges részterületet, illetve annak egyes összetevőit vizsgálja.
Műszaki menedzser alapszak munkaerőpiaci megítélése és fejlesztési lehetőségei a Szolnoki Főiskolán
Authors: László Éva , Jakopánecz Eszter , Törőcsik Mária 
Published: January 2021

A Szolnoki Főiskola képzésfejlesztési célból kutatást végzett a TÁMOP 4.1.1. C – 12/1/KONV-2012-2004 projekt keretében. A Szolnoki Főiskola azt a célt tűzte ki, hogy piaci információkkal segítse a Műszaki menedzser alapszak képzési stratégiájának fejlesztését. A szakértőket, oktatókat és hallgatókat megszólaltató kutatás eredményei aláhúzzák,hogy a Műszaki menedzser alapszak jövőjét illetően kulcsfontosságú a gyakorló vállalatokkal való szorosabb együttműködés: ezáltal lehetővé válik a piaci igényekre való gyorsabb reagálás, a legfrissebb tudás átadása, illetve a szakirány piaci elfogadottságának erősítése is. Azeredmények rávilágítottak, hogy a Szolnoki Főiskola jelenlegi képzési színvonala további fejlesztéseket igényel a kikerülő pályakezdők piacképességének erősítése érdekében, amelyben markáns kérdést jelent a kapcsolódó területek ismereteinek átadása is. A megfelelő szakmai alaptudás mellett határozott elvárás a nyelvek ismerete és a magas szintű kommunikációs képességek megléte.
ANÁLISIS CRIMINOLÓGICO CRÍTICO: TRATAMIENTO PENITENCIARIO COMO MEDIO PARA LA CONCRECIÓN DE LA FINALIDAD DE LA PENA-CASO ANTAURO HUMALA (COVID 19)
Authors: Hancco  Chipana Miriam Rosmery , Arocutipa Arocutipa Yeyset Nery 
Published: January 2021

Debido a la situación en la que nos encontramos a raíz de los impactos de la Covid-19 en la sociedad peruana, las autoras realizan un análisis criminológico crítico del caso Antauro Humala a propósito del Covid-19 con el objetivo principal de demostrar el actual estado del sistema penitenciario a propósito de la pandemia, para que, en base a los planteamientos de la criminología critica justifiquen la importancia y la necesidad de un tratamiento penitenciario óptimo orientado a la concreción de la finalidad de la pena.
Además, en el marco de la criminología crítica y cautelar analizan la conjunción de los conceptos del sistema penitenciario, tratamiento penitenciario y finalidad de la pena con el objetivo secundario de demostrar en qué medida el denominado “óptimo tratamiento penitenciario” y consecuentemente la concreción de la finalidad de la pena beneficia a la sociedad peruana.
Philosophical and legal foundations of the doctrine Marsil of Padua about the state
Authors: Борзов А.А. 
Published: January 2021

Учение представителя раннего итальянского гуманизма, выдающегося философа и правоведа, Марсилия Падуанского [1270(80) – 1342(43)] о государстве актуализирует платоновские политико-правовые идеалы. Мысль Платона о сущностном единстве человека и государства, формируемом общим источником их добродетели – идеей справедливости, составляет теоретическое основание гуманизма падуанца, его философско-правового учения о совокупной воле людей как источнике государственного суверенитета.
The teaching of the representative of early Italian humanism, an outstanding philosopher and lawyer, Marsil of Padua [1270 (80) - 1342 (43)] about the state actualizes Plato's political and legal ideals. Plato's thought about the essential unity of man and the state, formed by the common source of their virtue - the idea of ​​justice, constitutes the theoretical basis of Padua's humanism, his philosophical and legal doctrine of the collective will of people as a source of state sovereignty.
STATE SECURITY AND THE RIGHT OF A PERSON TO LIVE IN THE NATIVE LAND TERRITORIES RECOGNIZED AS SPECIALLY PROTECTED
Authors: Винокуров В.А. , Шафигулин К.В. 
Published: January 2021

В статье рассмотрены вопросы безопасности государства, связанные с проживанием лиц на исконной территории, которая признана особо охраняемой природной территорией. Проанализированы законы, действующие в Российской Федерации, выявлены проблемы, связанные с отсутствием нормальной регламентации жизни и деятельности лиц, проживающих на землях своих предков, которые были отнесены к категории земель, особо охраняемых государством. Обозначены особенности проживания на таких территориях лиц, отнесенных к коренным малочисленным народам России. Одновременно прослежена связь между вопросами национальной безопасности и ограничением права человека проживать и осуществлять необходимую для своей жизни деятельность на исконной территории.
В целях соблюдения установленных принципов безопасности государства, включая экологическую безопасность, а также для соблюдения прав лиц, проживающих на особо охраняемых природных территориях, в статье сформулированы предложения по внесению изменений в федеральные законы «Об особо охраняемых природных территориях» и «Об охране озера Байкал».
The article deals with the issues of state security related to the residence of individuals in the ancestral territory, which is recognized as a specially protected natural territory. The article analyzes the laws in force in the Russian Federation and identifies problems related to the lack of normal regulation of the life and activities of people living on the lands of their ancestors, which were classified as lands specially protected by the state. The features of residence in such territories of persons classified as indigenous small-numbered peoples of Russia are indicated. At the same time, there is a link between national security issues and restrictions on the right of a person to live and carry out activities necessary for their life on the ancestral territory.
In order to comply with the established principles of state security, including environmental safety, as well as to respect the rights of persons living in specially protected natural territories, the article contains proposals for amendments to the Federal laws "On specially protected natural territories" and "on the protection of lake Baikal".
Features of the formation Finnish municipalities of revenue part of budgets after 1995 reform
Authors: Дусаев Р.Н. , Туманов Р.В. 
Published: January 2021

Эта статья посвящена вопросам, связанным с особенностями формирования муниципальных бюджетов Финляндии после принятия Муниципального Кодекса 1995 года. Авторы анализируют новые источники поступления доходов в муниципальные бюджеты. Также они анализируют особенности налогообложения муниципальных концернов и консорциумов, которые были созданы некоторыми муниципалитетами при взаимном сотрудничестве.
Также тут сказано об экономической помощи и попытках государства стимулировать развитие муниципалитетов во время экономического кризиса, как в краткосрочный, так и в долгосрочной перспективе.
Кроме того, в этой статье авторы также анализируют новые общегосударственные долгосрочные программы по выравниванию экономического развития муниципалитетов с низкими и высокими доходами.
This article deals with questions peculiarities of Finland’s municipal budgets formation after passing the Municipal Code of 1995. Authors analyze new sources of revenue return into municipal budgets. Also they analyze peculiarities of taxation to municipal concerns and consortiums, which were created by some of municipalities under mutual cooperation.
It also talks about economic assistance and the state's attempts to stimulate the development of municipalities during the economic crisis, both in the short and long term.
There also was said economical aid about and attempts by the state to stimulate development of municipalities at the time of economical crisis as in shatters as in long term perspective.
Beside that in this article authors also analyze new common to whole state bong term programs about equalization of economical development of municipalities whit high level and low level incomes.
Formation and development domestic legislation on the carriage of goods by sea from the end of the 17th to the period of the reign of Catherine II
Authors: Хабибулаев А.Х. 
Published: January 2021

В статье рассматриваются основные вопросы становления и развития законодательства о морской торговле, о перевозке грузов, о развитии судостроения и мореходного дела. Особое внимание уделено периоду до правления Петра I. Автор приходит к выводу, что морская торговля сложилась еще до Петра I, и торговое мореплавание регулировалось торговыми соглашениями и царскими грамотами, а при Петре I получило новый виток развития, с учетом опыта судостроения зарубежных стран. Мореходные кампании купцов дали начало казенной морской торговли и созданию военно-морского флота, способствовали развитию правового регулирования внешнеторговых операций морским транспортом.
The article deals with the main issues of the formation and development of legislation on sea trade, on the carriage of goods, on the development of shipbuilding and maritime business. Particular attention is paid to the period before the reign of Peter I. The author comes to the conclusion that sea trade developed even before Peter I, and merchant shipping was regulated by trade agreements and tsarist charters, and under Peter I it received a new round of development, taking into account the experience of shipbuilding in foreign countries. The seafaring campaigns of merchants gave rise to state-owned sea trade and the creation of the navy, contributed to the development of legal regulation of foreign trade operations by sea transport.
Efficiency of Prosecutor's supervision over the implementation of laws by preliminary investigation bodies at the stage of initiation of criminal cases on crimes in the budget sphere
Authors: Лебедева Скачкова А. Е. 
Published: January 2021

В статье рассматривается проблематика неотвратимости уголовной ответственности за преступления в бюджетной сфере на стадии разрешения вопроса о возбуждении уголовного дела с позиции эффективности деятельности государственных органов, значение и роль органов прокуратуры.
The article examines the problem of inevitability of criminal liability for crimes in the budgetary sphere at the stage of resolving the issue of initiating a criminal case from the standpoint of the effectiveness of the activities of state bodies, the importance and role of prosecutors.
MEASURING CONTAGION EFFECT OF GREEK SOVEREIGN DEBT CRISIS ON INDONESIA
Authors: Setiawan Arif 
Published: January 2021

Abstraksi
Saat krisis utang Yunani memuncak, banyak negara terkena efek domino sampai derajat tertentu. Indonesia mungkin terkena juga dampak dari krisis walaupun tidak ada jalur yang kuat untuk mengalirkan krisis. Sampai saat ini krisis utang Yunani belum berakhir sepenuhnya dan karenanya perlu untuk mengevaluasi dampak dari krisis terhadap ekonomi Indonesia untuk antisipasi kemungkinan krisis susulan. Menggunakan model Vector Auto Regressive (VAR) untuk menangkap hubungan antara tingkat harga instrumen Credit Default Swap antara dua negara: Indonesia dan Yunani, penelitian ini melakukan estimasi dampak krisis Yunani terhadap Indonesia melalui Impulse Response Function berbasis parameter model VAR. Hasil estimasi menunjukkan dampak krisis Yunani terhadap Indonesia adalah sangat lemah. Hal ini mengindikasikan bahwa investor mungkin telah menyadari bahwa ekonomi Indonesia cukup terisolasi dari krisis Yunani dan karenanya tidak mengubah persepsi sovereign risk Indonesia.
Kata Kunci: Krisis Utang Yunani, Efek Domino, Model VAR, Impulse Response Function

Abstract
As Greece Debt Crisis emerged, many countries suffered contagion effect to some level. Indonesia might have been affected by the crisis even there was no strong link to transfers the shock. As the debt crisis has not yet over completely, we need to evaluate the impact of previous shock on Indonesian economy to anticipate the possibility of the next event. Employing Vector Auto Regressive (VAR) model to capture connection between Sovereign Credit Default Swap of two countries we found our estimation of Impulse Response Function of Indonesia CDS on shock in Greece CDS and concluded that the magnitude of debt crisis in uprising credit default risk on Indonesia was considered to be very low. This dynamic told us that investors may have learnt that Indonesian economy was quiet isolated from shock in Greece and they expected no change in the Indonesia sovereign risk.
Keywords: Greece Sovereign Debt Crisis, Contagion, VAR Model, Impulse Response Function
A Prospective Audit of Bed Utilisation and Delays in Care across London
Authors: Marinova Milka , Bell Lauren McKenzie , Watkin Simon , Bell Derek 
Published: January 2021

Background A prospective bed utilisation census of acute London hospitals using an established Day of Care Survey (DoCS), which quantified adult patients not meeting criteria for in-hospital care. Methods Twenty-three hospitals were surveyed over two weeks in October/ November 2017 using supervised trained hospital staff. Pairs of staff visited wards, reviewed all patients and identified those not meeting inpatient care criteria, recording reasons for delay. Patient demographics, length of stay (LOS), ward specialty and delay reasons were collected. Results Overall - In total, 8,656 in-patients were studied (overall occupancy 96%, range 82-117%): 800 definite discharges were excluded, leaving 7,856 patients for analysis; seven hospitals had ≥100% occupancy; 1,919/7,856 patients (24%, range 12-43%) did not meet criteria; 56% of patients were over 70 years; five hospitals had higher number of patients <70yo. 56% patients had LOS 0≤7days. Delayed patients - Number of delayed patients increased with age, but three hospitals had more patients <70yo; 53% had LOS≤14 days and 47% LOS>14 days; 13 hospitals had greater/equal number of patients in ≤14 days LOS. For delayed patients in ≤14 days group, most were within seven days of admission (627 ≤7days, 393 8-14 days). In total 34% (range 11-54%) of delays were related to acute hospital reasons (AHR) and 61% (range 46-83%) to wider system reasons (WSR). Eight common themes accounted for 67% of recorded reasons and were equally split between AHR and WSR. Conclusion Data showed high occupancy levels with insufficient discharges. This study suggests policies selecting age and/or LOS alone as cut offs to tackle delays in care may miss a large proportion of patients requiring more timely interventions. Adopting a proactive thematic approach to improvement using the top eight delay reasons provides an obvious opportunity to reduce delays while noting the inter site variation. All metrics analysed emphasized the need for informed local data to help support local change.