bluuebunny/crossref_metadata_2025_split huggingface dataset:
PGAM1 and TP53 mRNA levels in canine mammary carcinomas – Short communication
Authors: Maués Tábata , Oliveira Táya Figueiredo de , El-Jaick Kênia Balbi , Figueiredo Agnes Marie Sá , Ferreira Maria De Lourdes Gonçalves , Ferreira Ana Maria Reis 
Published: April 2021

AbstractTP53andPGAM1genes play a key role in glycolysis which is an essential metabolic pathway of cancer cells for obtaining energy. The purpose of this work was to evaluatePGAM1andTP53mRNA expressions in canine mammary carcinomas (CMC) and to correlate them with animal data and tumour histological features. None of the nine samples analysed revealedPGAM1DNA sequence variations.PGAM1andTP53RNA expressions from 21 CMC were analysed using a one-step reverse transcription-PCR kit and its platform system. Most CMC samples had low levels ofPGAM1mRNA (71.5%) and normal expression ofTP53mRNA (95.2%). Our results suggest a different feature of the Warburg effect on canine mammary cancer cells compared to human cells.
Acute colonic impaction and faecaloma due to canine benign prostatic hyperplasia – Case report
Authors: Ferré-Dolcet Lluis , Sussan Beatrice 
Published: April 2021

AbstractThe present case report describes the clinical signs and case resolution of an intact 9-year-old male crossbreed dog with spontaneous constipation. The dog presented with abdominal pain, lack of appetite, tenesmus and without signs of defecation in the last 4 days. No important alterations were observed in the complete blood count and biochemistry. A substantial obstruction caused by a faecaloma and a prostate with increased size was observed on X-rays. Benign prostatic hyperplasia (BPH) was confirmed by ultrasonography (size: 48.29 cm3) and by testing the serum canine prostate-specific arginine esterase concentration (105.97 ng/mL). Colon impaction was resolved with rectal enemas within two days. BPH was treated with osaterone acetate. Ultrasonographic checks were performed after 60 and 180 days from the demission and a concrete constant reduction of prostatic volume and of the clinical signs was established. Faecaloma is an uncommon finding in male dogs, and it occurs especially as a consequence of BPH. Colon impaction in patients with BPH is usually subclinical, but it is important to underline how, in severe cases, perforation of the colon and faecal peritonitis can occur, leading to fatal conditions for the animal. In conclusion, prostatic enlargement should always be considered in male dogs suffering from colonic impaction.
Le sentiment de puissance. Une approche anthropologique du fait religieux
Authors: Simonin David 
Published: April 2021

El objetivo de este artículo es explicar el análisis crítico de la religión que Nietzsche realiza gracias a su concepto de sentimiento de poder. Por un lado, la fe puede ayudar a los seres humanos a sentirse poderosos, aunque no necesariamente sean, por otro lado, ese proceso puede proporcionarles algún tipo de poder efectivo. El sentimiento de poder es, por tanto, una herramienta para comprender mejor numerosas actitudes y prácticas religiosas.
ISOTHERMAL CURING KINETICS OF POLYMETHACRYLIMIDE/NANO-SiO2 COMPOSITES BASED ON A DYNAMIC THERMOMECHANICAL ANALYSIS
Authors: Zhang Jing , Wu Yi-min , Ma Xu , Huang Bao-Yu , Lv Song , Jiang Jia-xing , Tang Ji-Jun 
Published: April 2021

The isothermal curing kinetics of polymethacrylimide/nano-SiO2 composites were investigated using a dynamic thermomechanical analysis. The relative conversion was defined with the storage modulus. The Avrami model-fitting method, Friedman method and integral method were applied to analyze the curing kinetics. The storage modulus and loss modulus increased appreciably, spanning three orders of magnitude throughout the curing. The frequency correlation of the relative conversion was noticeable at 180 °C because the glass transition took place when the curing degree was not high enough. The Avrami model-fitting analysis gave good fits for the experimental data. The activation energy calculated with the Avrami equation changed from 65.46 kJ/mol to 25.28 kJ/mol at 180–190 °C, while at 190–200 °C, the activation energy changed from 107.14 kJ/mol to 63.82 kJ/mol. The model-free analysis revealed the dependence of the activation energy on the relative conversion. The activation energy increased from 104.3 kJ/mol to 130.6 kJ/mol with the use of the Friedman method when the relative conversion ranged between 0.4–0.8. Similarly, the activation energy calculated with the integral method increased from 71.5 kJ/mol to 103.4 kJ/mol. When the relative conversion exceeded 0.8, the activation energy decreased gradually. The mobility of the reactive groups was hindered and the crosslinking density of the composite was much higher. The curing kinetics became diffusion controlled. The activation energy of the PMI/SiO2 composite was greater than that of PMI, which could be attributed to the hindrance effect caused by nano-SiO2.
Hybrid LRU Algorithm for Enterprise Data Hub using Serverless Architecture
Authors: Murugan Dr. 
Published: April 2021

In hybrid LRU algorithm was built to execute parameterized priority queue using Least Recently Used model. It helped to determine the object in an optimum mode to remove from cache. Experiment results demonstrated ~30% decrease of the execution time to extract data from cache store during object cache extraction process. In the era of modern utility computing theory, Serverless architecture is the cloud platform concept to hide the server usage from the development community and runs the code on-demand basis. This paper provides Hybrid LRU algorithm by leveraging Serverless Architecture benefits. Eventually, this new technique added few advantages like infrastructure instance scalability, no server management, reduced cost on efficient usage, etc. This paper depicts about the experimental advantage of Hybrid LRU execution time optimization using Serverless architecture.
Modern Approaches to Arctic Development in View of Synergy Potential in the New Risks and challenges Environment
Authors: Bondareva N. N. 
Published: April 2021

Purpose of this article is to consider methodological and organizational approaches in managing the development of the Arctic zone of the Russian Federation as a complex system at various levels, from the project level to the global level, taking into account the synergy of the potential of the economic platform and the synergy of risks and threats.Methods: the research presented in the article is based on the use of theoretical foundations of managing target processes for solving complex Arctic development problems, applying methods of system analysis, operations research and economic analysis of the development of complex systems from the view of synergy effects. Methods for analyzing the emergence of complex systems, the balance of dynamic integrity, evolutionary development and chaos management, and specific resistance activity were also used.Results: mnsideration of the experience of the complex intensification of the Russian Arctic economic potential at different territorial levels through the system filling with better synergies management of the potential of private-state partnership is presented. It makes possible to identify both the results achieved and the current and future threats and challenges of the region. The author of the study disclosed the organizational and methodological problems of Arctic management, assessed the limitations for the full-scale launch of synergistic management models.Conclusions and Relevance: the presented results of the analysis set the management vector for maximum synergistic activation of financial, logistical and intellectual resources to achieve sustainable, holistic and safe development of the Arctic. The proposed methodological approaches will minimize synergistic resistance of risks and threats to the current policy of the Russian Arctic competitiveness growth.
The Determinants of Income Inequality in Bangka Belitung Province
Authors: Nesha R. , Bernadette R. , Yulianita A. 
Published: April 2021

Purpose: this research study focused on analyzing the conditions of income distribution and the determinants of the low Gini coefficient, namely the sectors that have the highest contribution, including the industrial, agricultural and trade sectors and labor productivity in the industrial sector in Kepulauan Bangka Belitung Province.Methods: the income distribution phenomenon in Kepulauan Bangka Belitung Province during the 2007-2018 period became the basis for analyzing the determining variables of income distribution including the industrial sector, the agricultural sector, the trade sector and the industrial labor productivity. The income distribution indicator was measured from the Gini coefficient value using the Panel Data Regression approach to determine the effect of these variables on the Gini coefficient in all regencies / cities in the Kepulauan Bangka Belitung Province.Results: the results showed that the agricultural sector, industrial sector and trade sector had a negative and significant effect on the Gini coefficient. Meanwhile, labor productivity in the Industrial Sector had a significant positive effect on the Gini coefficient. The results showed that the determinant of income distribution was the agricultural sector. Further findings prove that the agricultural, industrial and trade sectors improved the income distribution.Conclusions and Relevance: this study implied for the efforts to increase the agricultural market orientation towards high productivity which was inversely contrast to the output of workers in the industrial sector proven to reduce income distribution. Therefore, the structural transformation towards industrialization and market-oriented efforts from the agricultural sector were necessary.
Solar radiation power and its distribution in altitude‐latitudeintervals of the territory of Dagestan, Russia
Authors: Akhmedovа L. Sh. 
Published: April 2021

Aim. Calculation of the energy potential of primary land productivity, environmental regulation of technogenic load and development ofmeasures for sustainable development of territories.Materials and Methods. The author has developed a method for assessing the spatial differentiation of solar radiation power in relation to the territory of the Republic of Dagestan. The method is based on the results of long‐term actinometric measurements taken atmeteorological stations at different altitudes in Dagestan and adjacent territories.Results. A statistical analysis has been carried out of the regularities of the distribution power of solar radiation in coordinates of the territory of the Republic of Dagestan. On the basis of calculated regularities, a nomogram was constructed for reading the indicators of the energy of ecosystems in the latitudinal‐altitudinal intervals of the earth's surface of the Republic of Dagestan. The resulting nomogram allows the reading of the limits and average values of the characteristics of solar radiation in an area studied, for example, for all intervals of heights and latitudes in an administrative region.Conclusion. The results obtained are necessary for the calculation of the energy potential of primary productivity of lands, ecological regulation of anthropogenic load, as well as the development of measures for sustainable, balanced ecological and economic development of territories.
Motor activity of sheep on pasture in the conditions of Eastern Siberia, Russia
Authors: Khamiruev Т. N. , Bazaron В. Z. , Volkov I. V. , Dashinimaev S. M. , Chernykh V. G. 
Published: April 2021

Aim.To study the motor activity of sheep of the Zabaykal (Transbaikal) and Agin breeds in year‐round grazing in relation to the season of the year.Material and Methods.The research was carried out in the steppe zone of the Aginsky District of Zabaykalsky Territory. Garmin eTrex 20x GPS receivers were used in the research with the help of which motor activity and the speed of sheep in pasture were monitored. Weather conditions were taken into account for the relevant research periods using data from the meteorological service.Results.Average daily air temperature in winter was – 23.30°C, air velocity 1.3 m/s and relative air humidity 67.3%, and in spring was 13.70°C; 4.1 m/s and 35.6%, in summer – 20.90°C; 1.6 m/s and 77.3% and in autumn – 1.10°С below zero, 2.4 m/s and 50.1%. It was found that the sheep being monitored travelled different distances with different speeds of movement depending on the season of the year and origin. They travelled the greatest distance in winter with a higher average speed of movement and a shorter distance in the summer. At the same time, it was noted that semi‐coarse‐wooled (Agin) sheep passed 12378 m during the 8‐hour grazing period, which is 24.9% more than fine‐wooled (Zabaykal) sheep (Р˂0.01), in spring – 8,168 m (22.3% more, Р ˂0.05), summer – 6,511 m (24.5% more, Р˂0.01) and autumn – 9,214 m (40.3% more). The average speed of movement of semi‐coarse‐wooled sheep was higher than fine‐wooled by 80.0% (P˂0.05), 25.0, 9.1 and 23.1% (P˂0.05), respecƟvely. The nutritional value of 1 kg of dry matter of pasture grass was higher in the summer and amounted to 0.68 units with a content of 1 unit 93.1 g of digestible protein.Conclusion.The research data allow us to conclude that the motor activityand the speed of movement of sheep in pasture directly depends on the season of the year and the nutritional value of pasture grass, as well as on type of breed.
The state of hydrobionts in the Tyub‐Karagan Bay structure, Kazakhstan
Authors: Kenzhegaliev A. , Kanbetov A. Sh. , Abilgazieva A. A. , Sakhmanova A. К. , Kulbatyrov  D К. 
Published: April 2021

Aim. The purpose of the research was to study the state of hydrobionts in the Tyub‐Karagan Bay structure by season for a comparative analysis of their state with previous studies by the authors.Material and Methods. The conditions of hydrobionts (phyto, zoo‐plankton and macrozoobenthos) of the Tyub‐Karagan Bay structure have been studied for three seasons. Studies were carried out by traditional methodology.Results. The species composition of phytoplankton communities in spring was found to be less constant than in autumn; this is associated with heterogeneity in external conditions at the beginning of the growing season. The seasonal dynamics of zooplankton conformed to certain patterns. As a rule, from the beginning to the end of the growing season there was an enrichment of species composition and an increase in the quantitative indicators of zooplankton communities. The highest biomass was formed by bottom cenoses, where large mollusks play a leading role.Conclusion. During the 2018 research period, species richness and species diversity of phytoplankton were at a high level. Representatives of two categories were observed most often. Blue‐green dominated in number, while diatoms formed the basis of biomass. Species richness and species diversity of zooplankton was at a low or moderate level and most often constant. The seasonal dynamics of macrozoobenthos had common and specific features, depending on the research station location. Disproportionate changes in the quantitative indicators of bentonites are associated with a decrease in the average weight of individuals by autumn. This happened both through the strengthening of the role of small species and by an increase in the proportion of younger age stages in populations of bottom invertebrates.
Summer‐flowering trees and shrubs in landscaping for the south‐eastern coast of the Crimea
Authors: Klimenko N. I. , Potapenko I. L. , Klimenko О. Е. 
Published: April 2021

Aim. To study the species composition, form diversity, bioecological features of summer‐ flowering trees and shrubs in green spaces of the south‐eastern coast of the Crimea and suggest ways to expand the range. Materials and Methods. The green spaces of Feodosia, Sudak and the localities of Semidvorye, Solnechnogorskoye, Malorechenskoye, Rybachye, Morskoye, Novy Svet, Solnechnaya Dolina, Shchebetovka, Kurortnoye, Koktebel and Primorskiy were investigated. Bioecological and phenological studies of ornamental trees and shrubs were undertaken according to generally accepted methods. Results. The species composition and shape diversity of summer‐flowering trees and shrubs in green plantings of Crimea’s south‐eastern coast were identified. It was found that summer‐ flowering plants make up almost half of the species composition (48.6%) used in landscaping. However, only 23 species are widespread throughout the region, such as Ailanthus altissima (Mill.) Swingle, Albizia julibrissin Durazz., Buddleja davidii Franch., Campsis radicans (L.) Seem., Elaeagnus angustifolia L. etc. The greatest number of species and forms of arboreal plants bloom in early summer, their number decreasing significantly from the second decade of June. Conclusion. An assortment is proposed for increasing the number of trees and shrubs which flower during the summer, taking into account both their decorative visual appeal and their environmental requirements, especially drought and frost resistance. Of great interest are species that bloom from June onwards, especially those which are highly decorative and have a long flowering period, such as Albizia julibrissin, Buddleja davidi and forms, Hydrangea arborescens L., Campsis radicans, Kerria japonica f. plena C.K. Schneid, Robinia viscosа Vent., Vitex angus‐castus L.
ANALISIS RESPON SISWA SMA PLUS AL-AZHAR JEMBER TERHADAP MODUL FISIKA DIGITAL BERBASIS ARTICULATE STORYLINE 3 POKOK BAHASAN HUKUM NEWTON TENTANG GRAVITASI
Authors: Midroro Jihan Ni'ami , Prastowo Sri Handono Budi , Nuraini Lailatul 
Published: April 2021

Abstract: The Covid-19 pandemic has an impact on many things, one of which is education. Changes that occur in the field of education are a learning system that is used as a distance learning system. Physics is a subject that is considered less attractive and tends to be boring. One of the reasons physics is considered boring is the lack of learning media to support physics material, especially digital ones. The purpose of this study was to analyze the responses of Al-Azhar Jember Senior High School students after using physics learning media in the form of an interactive digital physics module based on Articulate Storyline3, the subject of Newton's law about gravity. This research method is a quantitative research method using an instrument in the form of a response questionnaire given to class X MIPA SMA Plus Al-Azhar Jember via the google form page. Based on the research that has been done, it shows that digital physics moul gets a very positive response from respondents. The digital physics module obtained a score of 81, 60% on a limited scale trial and a score of 83.86% on a wide-scale trial.

Keywords: digital module, physics learning, students response
PEMANFAATAN ITERATED FUNCTION SYSTEM (IFS) UNTUK MEMBANGKITKAN MOTIF ANYAMAN UKURAN n x n
Authors: Maris Ingka , Purnomo Kosala Dwidja , Juliyanto Bagus 
Published: April 2021

Woven is one of art thats very close to life. Woven has a pattern consisting of two-dimensional (2D) and has a basic pattern. Along with the development times, technology is also growing including computer technology. Computer can be used for mathematical calculation process, one of them is fractal. Fractal Sierpinski carpet is formed from a square that use Iterated Function System (IFS) method. This method is exact self-similar resulting in the same fractal with the original constituent object. The writer want to get woven pattern using computer technology, that is GUI application in Matlab that utilizes the IFS method on fractal. Woven patterns formed from woven that have a grid size of n x n and are given a few iterations. So, that it can make it easier for craftsmen to make woven pattern that are interesting and varied.
Economic Activities of Natural Herbal Homes Lestari Herbal Village as a Learning Resource on Social Studies
Authors: Fatimah Desy , Winarso Heru Puji , Handy Muhammad Rezky Noor 
Published: April 2021

Aktivitas ekonomi konstruktif berbasis lingkungan dapat diintegrasikan secara kontekstual pada pembelajaran IPS. Rumah Herbal Alam Lestari di Komplek Bukit Permata Indah (Kampung Herbal) Banjarbaru merupakan usaha yang menjual berbagai produk obat herbal. Artikel ini bertujuan mendeskripsikan aktivitas ekonomi di Rumah Herbal Alam Lestari yang memanfaatkan lingkungan untuk ditanami tumbuhan herbal dalam upaya meningkatkan taraf hidup masyarakat sekaligus sebagai lingkungan hijau. Metode Penelitian ini menggunakan metode deskriptif yang untuk mendapatkan data melalui observasi, wawancara, dan dokumentasi. Data yang didapat direduksi, disajikan dalam bentuk narasi yang dilengkapi gambar dan tabel analisis materi untuk selanjutnya disimpulkan. Keabsahan data melalui triangulasi waktu, sumber, dan teknik. Hasil penelitian mendeskripsikan aktivitas ekonomi Rumah Herbal Alam Lestari memproduksi dua macam produk yaitu obat herbal dan tumbuhan langsung dari ukuran besar maupun kecil, didistribusikan dan dikonsumsi atau digunakan oleh masyarakat, dengan aktivitas ekonomi ini dapat diintegrasikan sebagai sumber belajar IPS di kelas VII pada materi aktivitas ekonomi (produksi, distribusi, dan konsumsi) yang berkonsep lingkungan.
MODERN SLAVERY IN FISHING INDUSTRY: THE NEED TO STRENGTHEN LAW ENFORCEMENT AND INTERNATIONAL COOPERATION
Authors: Yuliantiningsih Aryuni , Barkhuizen Jaco 
Published: April 2021

<span lang="EN-GB">The global fishing industry supports the livelihoods of millions, however, it adversely allows the occurrence of crimes throughout the value chain, especially modern slavery. This research aims to examine the current existence of slavery in the fishing industry for the state to determine the best way to deal with its repeated occurrence. Studies show that slavery still exists due to the vulnerability of the fishing sector. These include the prolonged timeframe on</span><span lang="EN-GB">board which prevents the crew from leaving the vessel, poor working conditions, the long-hours associated with the catching process, lack of access to authorities, use of foreign flags to create barriers to the law enforcement, use of migrant labour lacking representation and </span><span>the </span><span lang="EN-GB">lack of governmental oversight or support</span><span lang="EN-GB">. This research states that it is important to combat modern slavery by strengthening law enforcement, policy, and international cooperation between States, by involving the </span><span>s</span><span lang="EN-GB">ource, flag, coastal, port, trade and market State</span><span>s</span><span lang="EN-GB"> based on international and national law</span>
THE PARTICIPATION OF THE BREEDERS : REGIONAL REGULATION OF DUMAI CITY CONCERNING LIVESTOCK AND PETS
Authors: Afrizal Dedy , Al-Amaren Emad Mohammed , Yusuf Irfan Murtadho 
Published: April 2021

<em>This article aims to look at community participation in implementing Dumai City Act Number 10 of 2008 concerning livestock and pets, namely what impacts arise and what sanctions will be received if they do not comply and what are the anticipatory actions of the breeders so that they will not suffer losses in the future. This study is a qualitative research categorized as sociological juridical research. The data analysis was conducted using descriptive analysis. The results showed that the breeders (livestock farmers)’ lack of understanding on the regulations that had been set was one of the obstacles arising in the implementation of the law. It is hoped that the related parties involved in this Regional Regulation understand the legal sanctions and the impacts that arise from any disobedience acts. From various community backgrounds and in terms of educational factors, cultural factors, geographical aspects, and facility factors, it appears that the government's role in creating all aspects involved in jointly implementing this regional regulation is requiredBesides, breeders must implement these regional regulations as a form of anticipatory action; thus, such livestock and pet activities will not harm themselves and their environment.</em>