bluuebunny/crossref_metadata_2025_split huggingface dataset:
Patient re-presents to the clinic with reactive arthritis in the right hip after covid-19 infection: A case report
Authors: Shokraee Kamyar , Moradi Soroush , Eftekhari Tahereh , Shajari Rasoul , Masoumi Maryam 
Published: February 2021

Abstract
Background: SARS-COV-2, first reported in December 2019, usually presents with respiratory symptoms but can have various other manifestations and sequelae. One of the rare complications of COVID-19 infection is Reactive Arthritis. This complication is more likely to occur following sexually transmitted or gastrointestinal infection.Case presentation: Herein, we report a 58 years old woman hospitalized following COVID-19 infection and was discharged after a week. She consequently presented to the clinic ten days after her discharge, complaining of walking difficulties and radiating pain in her right hip. After ultrasound and MRI, she was diagnosed with reactive arthritis inflammation in the hip’s neck. Other known microorganisms responsible for reactive arthritis were ruled out before attributing it to the earlier COVID-19 infection. She reached remission after being treated using a combination of indomethacin and depot methyl-prednisolone for 14 days. Conclusion: To our knowledge, this is the first case of reactive arthritis caused by SARS-COV-2 in the hip. Further attention should be paid to symptoms occurring after an episode of infection with COVID-19 in order to expand our understanding of the disease and the symptoms with which it can manifest.
An innovative high frequency hyperthermia approach against SARS-CoV-2 and related virus: feasibility analysis
Authors: Cutolo Maria Alessandra , Migliaccio Antimo , Altucci Lucia , Cutolo Antonello , Cusano Andrea 
Published: February 2021

Abstract
Heating is a strong enemy of SARS-CoV and related virus. Starting from both this consideration and from the basic principle of the microwave ovens which are based on the strong absorption, from organic tissues, of the radiation centered around 2.15 GHz, we examine the feasibility of using this frequency range to both lower the strength of the SARS-CoV (and related virus) inside the human body and to easily sterilize objects or closed rooms. We underline that this is only a preliminary theoretical feasibility analysis, which, of course, should be experimentally proven.
Extraction and Characterization of Fiber Treatment Inula Viscosa Fibers as Potential Polymer Composite Reinforcement
Authors: Nafissa Moussaoui , Mansour Rokbi , Hocine Osmani , Jawaid Mohammad , Atiqah A. , Asim Mohammad , Lamia Benhamadouche 
Published: February 2021

Abstract
This research aims to analyze the newly discovered cellulosic fiber from the bark of Dittrichia viscosa, or Inula viscosa (IV), and evaluate the effects of permanganate and alkali chemical treatments on the physical properties to improve the interfacial bonding between Inula viscosa reinforced polymer composites. These permanganate and alkali treatments are both efficacious in helping in reducing hydrophilicity and eliminating impurities from the fiber surface, which has been confirmed by scanning electron microscope (SEM) observation, thermogravimetric analysis (TGA), X-ray diffraction (XRD), and Fourier Transform Infrared Spectrometry (FTIR). Permanganate-treated IVFs have shown higher tensile strength and interfacial stress resistance (IFFS) than alkaline IVFs, and untreated IVFs by tensile and droplet tests. The different characteristics were studied and compared with other bark fibers already available. It is estimated that the fiber treatments will enable high-quality IVF-reinforced polymer composites for use in the industry.
Sporadic Hand, Foot and Mouth Disease Cases Associated With Non-C4 Enterovirus 71 Strain in Xiamen, China From 2009-2018
Authors: Chen Mengyuan , He Shuizhen , Yan Qiang , Zhang Jianmei , Li Caiyu , Su Xiaosong , Zhang Shiyin , Li Tingdong , Ge Shengxiang , Chen Min , Zhang Jun , Xia Ningshao 
Published: February 2021

Abstract
EV71 has caused large HFMD epidemics among young children and EV71 infection was the leading cause of severe cases and deaths. In mainland China, almost all EV71 strains were segregated into C4 sub-genotype and prevalence of non-C4 EV71 strains was still unclear in mainland China. This study aimed to comprehensively report this in Xiamen. 5’UTR and VP1 Sequences of the strains were amplified by RT-nested-PCR and then sequenced. 32 non-C4 EV71 strains were identified in Xiamen during the study. This study would provide important information for related fields and provide new insights of EV71 strains in China.
Clinical Translational Evaluation of Al18F-NOTA-FAPI for Fibroblast Activation Protein Targeted Tumour Imaging
Authors: Wang Shuailiang , Zhou Xin , Xu Xiaoxia , Ding Jin , Liu Song , Hou Xingguo , Li Nan , Zhu Hua , Yang Zhi 
Published: February 2021

Abstract
PurposeIn this study, a novel Al18F-NOTA-FAPI probe was developed for fibroblast activation protein (FAP) targeted tumour imaging, which was available to achieve curie level radioactivity by automatic synthesizer. The tumour detection efficacy of Al18F-NOTA-FAPI was further validated both in preclinical and clinical translational studies. MethodsThe radiolabeling procedure of Al18F-NOTA-FAPI was optimized. Cell uptake and competitive binding assay were completed with U87MG and A549 cell lines, to evaluate the affinity and specificity of Al18F-NOTA-FAPI probe. The biodistribution, pharmacokinetics, radiation dosimetry and tumour imaging efficacy of Al18F-NOTA-FAPI probe were researched with healthy Kunming (KM) and/or U87MG model mice. After the approval of ethical committee, Al18F-NOTA-FAPI probe was translated into clinical for the PET/CT imaging of first 10 cancer patients. ResultsThe radiolabeling yield of Al18F-NOTA-FAPI was 33.8 ± 3.2% through manually operation (n = 10), with the radiochemical purity over than 99% and the specific activity of 9.3-55.5 MBq/nmol. Whole body effective dose of Al18F-NOTA-FAPI was estimated to be 1.24E-02 mSv/MBq, lower than several other FAPI probes ( 68Ga-FAPI-04, 68Ga-FAPI-46 and 68Ga-FAPI-74). In U87MG tumour bearing mice, Al18F-NOTA-FAPI showed good tumor detection efficacy from the results of micro PET/CT imaging and biodistribution studies. In organ biodistribution study of human patients, Al18F-NOTA-FAPI showed lower SUVmean than 2-[18F]FDG in most organs, especially in liver (1.1 ± 0.2 vs. 2.0 ± 0.9), brain (0.1 ± 0.0 vs. 5.9 ± 1.3), and bone marrow (0.9 ± 0.1 vs. 1.7 ± 0.4). Meanwhile, Al18F-NOTA-FAPI do not show extensive bone uptakes, and was able to find out more tumour lesions than 2-[18F]FDG in the PET/CT imaging of several patients. ConclusionAl18F-NOTA-FAPI probe was successfully fabricated and applied in fibroblast activation protein targeted tumour PET/CT imaging, which showed excellent imaging quality and tumour detection efficacy in U87MG tumour bearing mice as well as in human cancer patients.
Process Water Recirculation During Hydrothermal Carbonization as a Promising Process Step Towards the Production of N-doped Carbonaceous Materials
Authors: Wüst Dominik , Arauzo Pablo , Habicht Sonja , Cazana Fernando , Fiori Luca , Kruse Andrea 
Published: February 2021

Abstract
Hydrothermal Carbonization (HTC) refers to the conversion of biogenic wastes into char-like solids with promising perspectives for application, but a process water (PW) results which is difficult to dispose untreated. Thus, a biorefinery approach including one or two recirculation steps with the additional objective of improving the physico-chemical characteristics of the solid was performed. During HTC, constitutive biomass molecules decompose into hundreds of organic compounds, following complex reactions. To get deeper insights a combination of proximate, ultimate and structural analysis for solid products as well as liquid chromatography for liquid products were the choice. The main reactions could be identified by key compounds of low and high molecular weight resulting from hydrolysis, dehydration, decarboxylation, deamination as well as amide formation and condensation reactions. Their intensity was influenced by the feedwater pH and reaction temperature. Reactions of Maillard character result in N-containing heterocycles incorporated into the hydrochar (HC), which promises the fabrication of high added-value materials, i.e. N-doped carbonaceous materials.
The Impact of COVID-19 on Adolescents with Eating Disorders: A Cohort Study
Authors: Spettigue Wendy , Obeid Nicole , Erbach Madison , Feder Stephen , Finner Natalie , Harrison Megan E. , Isserlin Leanna , Robinson Amy , Norris Mark L. 
Published: February 2021

Abstract
Background: There is a noticeable lack of evidence regarding the impact of COVID-19 and the associated lockdown on young people with eating disorders. The goals of this study were 1) to examine characteristics of adolescents presenting for eating disorder (ED) assessment since the onset of the COVID-19 pandemic; 2) to compare adolescents presenting for ED assessment since the onset of the COVID-19 pandemic to those that presented for assessment one year previously; 3) to examine implications of the pandemic on the system of care. Methods: A retrospective chart review was completed on all patients assessed at a pediatric tertiary care ED program during the pandemic between April 1 and October 31, 2020, and on youth assessed during the same time frame one year previously. Data including body measurements and results of psychological measures was extracted from patients’ charts. Clinician reports were utilized for accounts of ED symptoms. Referrals to our program were also compared for the two time periods.Results: Of the 48 youth assessed between April and October 2020, average age was 14.6 years and average percentage of treatment goal weight was 77.7%. 40% cited the pandemic as a trigger for their ED; of these youth, 78.9% were medically unstable compared to 55.2% of those whose ED was not triggered by the pandemic. When comparing the 2020 cohort to those assessed in 2019, youth who presented for assessment during the pandemic trended towards having lower percentage of goal weights and higher rates of self-reported impairment, and were significantly more likely to be medically unstable and to require hospitalization. Higher rates of inpatient admissions, emergency room consultation requests and outpatient referrals deemed “urgent” were likewise associated with the pandemic period.
Changes in retina's vascular and nervous structures in patients with hypertension
Authors: Zhao Run-ze , Fernández Melba Márquez , Toledo Maria Cáceres , Barbeito Teddy Osmin Tamargo , Zhang Guo-xun , Zhang Wen-ting 
Published: February 2021

Abstract
Introduction: This study aims to analyze the correlation between hypertension (HTN) and changes in the retina's vascular and nervous structures in patients with hypertension.Method: This was a cross-sectional study, which included a group of 45 subjects who did not suffer from hypertension (HTN) (Group 1), other two groups of 51 patients with controlled (Group 2) and not controlled (Group 3) HTN. Changes in vascular and nervous structures were identified and evaluated by ophthalmoscopy and OCT, respectively. Parametric and non-parametric tests, Post-hoc, Pearson, and Spearman correlation were used, with p<0.05 considered statistically significant.Results: We observed hypertensive retinopathy (HTNR G I and II) in both groups with HTN, with a significant difference (p=0.023). We found a lower average retinal nerve fiber layer (RNFL), the average and minimum ganglion cell complex (GCC) in the patients of groups 2 and 3 than those of group 1. We found a negative and slight correlation between systolic blood pressure (SBP), diastolic blood pressure (DBP), and HTNR with superior GCC thickness in hypertensive patients.Conclusions: hypertension correlated to changes in the retina's vascular and nervous structures, and the nervous structure alterations were not visible by ophthalmoscopy but detected by OCT.
Passing pigtail through snare technique: an easy and fast way to retrieve a catheter fragment with inaccessible ends
Authors: Mori Kensaku , Somagawa Chika , Kagaya Shun , Sakai Masafumi , Honma Satoshi , Nakajima Takahito 
Published: February 2021

Abstract
Background: A catheter fragment with inaccessible ends can be retrieved using the well-known two-step method: making a free end with a pigtail catheter and seizing it with a snare catheter. Here we propose an easier and faster modification, named the “passing pigtail through snare” technique. Case presentation: A 61-year-old female patient underwent removal of a central venous catheter fragment migrating to the right atrium. Both ends located in the right atrial appendage and left hepatic vein were inaccessible. Initially, a snare loop was opened in the inferior vena cava and a pigtail catheter was advanced through the snare loop to hook the catheter fragment. The free end was created by pulling the pigtail catheter, dragged automatically into the snare loop, grasped, and retrieved immediately. Conclusions: By passing the pigtail catheter through the snare loop in advance, the snaring maneuver becomes easy and fast in retrieving the catheter fragment with inaccessible ends.
Modelling Daily Surface Runoff, Sediment and Nutrient Loss at Watershed Scale Employing APEX Model Interfaced with GIS – A Case Study in Himalayan Landscape
Authors: Kumar Suresh , Singh Ravinder Pal , Kalambukattu Justin George 
Published: February 2021

Abstract
Daily surface runoff, sediment and nutrient loss data collected from a watershed located in Uttarakhand state of Indian Himalayan region, in year 2010-2011 and of which half of the events data were used for calibration and remaining for validation. Model was calibrated for surface runoff, sediment loss and nutrient loss to optimize the input given to the model to predict the sediment loss, erosion and nutrient loss. The calibration was done by changing the sensitive parameters. Analysis showed that SCS CN number was found most sensitive to runoff, followed by saturated hydraulic conductivity, available water-holding capacity, CN retention parameter and C factor whereas erosion control practice (P) factor was found to be most sensitive, followed by C factor, sediment routing coefficient, average upland slope and soil erodibility (K) factor for the sediment and nutrient loss. APEX model calibrated for the watershed and it predicted quite well for the surface runoff (r=0.92, NSE=0.50), sediment loss (r=0.88, NSE=0.61 and nutrients of total carbon (r=0.78, NSE=0.59) and fairly for total nitrogen (r=0.77, NSE=0.19). Surface runoff was predicted well for low and medium rainfall; however, it was over predicted for high rainfall events. Over prediction may be attributed to the unaccountable conservation measures and practices which were not accounted by the model. Similarly, sediment loss was estimated on daily basis at the watershed scale and was well predicted for low and medium rainfalls but under-estimated for high rainfall events. The area is prone to landslips occurred at high rainfall events was not accounted by the model that may be a reason for under prediction of sediment loss by the model.
Structural, Linear and Nonlinear Optical Properties of Zn@CdO&nbsp;Nanostructured Thin Films: A Quantitative Comparison With Dft
Authors: Khan Ziaul Raza , Gandouzi M. , Alshammari Adullah S. , Bouzidi M. , Shkir Mohd. , Alfaify S. , Mohamed Mansour 
Published: February 2021

Abstract
This paper presents experimental and density functional theory (DFT) investigations of Zn doping role in the Zn@CdO ternary system. Zn doped CdO nanostructures with different Zn concentrations were successfully casted on glass substrates by sol-gel spin coating method. Cubic Zn@CdO structured ternary alloyed nanostructures thin films with 0.0%, 1.0%, 2.0% and 3.0% wt. Zn concentrations were obtained. An enhancement in the lateral growth of CdO cauliflower-like nanostructures was observed after Zn addition which leads to a 2D growth of nanostructured films with improved continuity. The effect of Zn doping on the linear optical parameters such as the optical band gap, the absorption index and the refractive index were also investigated. A remarkable blue shift in the band edge was observed as Zn is incorporated into the CdO matrix. In addition, the third order nonlinear optical parameters χ(3) and n2 were calculated and found to be about 2.89×10-12 - 4.33×10-14 esu and 2.89×10-12 - 4.33×10-14 esu; respectively. A density functional theory (DFT) based Wien2k package was utilized to theoretically investigate the lattice parameters, the electronic structure, the absorption index and the refractive index of the Zn@CdO ternary nanoalloys. The role of Zn doping on the aforesaid properties was theoretically investigated for 3.125%, 6.25%, 12.5% and 25% Zn doping concentrations and was compared with the experimentally determined parameters. The combined theoretical and experimental investigations presented herein along with the detailed discussion of the obtained findings would provide a deep understanding of the opto-electronic behavior of the Zn doped CdO nanostructured films as well as their suitability for devices applications.
Mechanisms of Impact and Experiences of a Person-Centred Transition Programme for Adolescents With Chd: The Stepstones Project
Authors: Saarijärvi Markus , Wallin Lars , Moons Philip , Gyllensten Hanna , Bratt Ewa-Lena 
Published: February 2021

Abstract
BackgroundDuring the past decade there has been some evaluation of transition programmes for adolescents with chronic conditions. However, this has rarely involved process evaluations focusing on mechanisms leading to outcomes, thus hampering implementation of these complex interventions. Our aim was to (I) describe adolescents’ and parents’ experiences of participating in a person-centred transition programme aiming to empower them in transition to adulthood and (II) explore the mechanisms of impact.MethodsA qualitative process evaluation was performed, embedded in a randomized controlled trial evaluating the effectiveness of a transition programme for adolescents with congenital heart disease in Sweden. A purposive sample of 14 adolescents and 12 parents randomized to the intervention were interviewed after participation in the programme. Data were analysed deductively and inductively in NVivo v12. ResultsExperiences of participation in the transition programme were generally positive. Meeting a transition coordinator trained in person-centred care and adolescent health and embarking on an educational process based on the adolescents’ prerequisites in combination with peer support were considered key change mechanisms. However, support to parents was not delivered as intended, resulting in ambivalence about changing roles and the unmet needs off parents who required additional support.ConclusionsParticipants experienced increased empowerment in several dimensions of this construct, thus demonstrating that the transition programme was largely implemented as intended and the evidence-based behaviour-change techniques used proved effective in reaching the outcome. These findings can inform future implementation of transition programmes and illuminate challenges associated with delivering a complex intervention for adolescents with chronic conditions.
Orbital Effect on Carbyne Based Sensor
Authors: Ahmadi Mohammad Taghi , Heidari Zahra , Rahmani Meisam , Ahmadi Mahan 
Published: February 2021

Abstract
Carbyne material with sp-hybridized atoms has been considered as a one dimensional structure with unique properties which has been widely used in nanotechnology. In the presented work the effect of electron overlap energy in the form of electron interaction with in the unit cell and nearest neighbors is explored. In addition, the band structure variation under proposed interaction in one dimensional carbyne is investigated. The effect of overlap energy variation inside and outside the unit cell on the band gap is intended. Under proposed structure the effective mass and density of states parameters are explored. It is demonstrated that by increasing the interaction between s and p orbitals in the unit cell, the band gap increases. However, the band gap is decreased by increasing the interaction between s and p orbitals out the unit cell which can be sued as a sensing mechanism.
Analysis of thromboembolic events in head and neck cancer patients who underwent concurrent chemoradiotherapy with cisplatin: A real-world study
Authors: Cho Hundo , Kang Seok Yun , Lee Hyun Woo , Choi Yong Won , Kim Tae-Hwan , Ahn Mi Sun , Choi Jin-Hyuk , Kim Chul-Ho , Shin Yoo Seob , Jang Jeon Yeob , Oh Young-Taek , Heo Jaesung , Sheen Seung Soo 
Published: February 2021

Abstract
Background

The risk of thromboembolic events (TEE) in cancer patients, especially those receiving cisplatin-based chemotherapy, is higher than that of general population.
Methods

The study investigated the incidence of TEE in 257 head and neck (H&N) cancer patients, during or within 6 months of completion of concurrent chemoradiotherapy (CCRT) with cisplatin, and analyzed factors affecting TEE occurrence.
Results

TEE occurred in 5 patients, an incidence rate of 1.9%. Khorana score was the only factor associated with TEE occurrence (p = 0.010).
Conclusions

The incidence of TEE in H&N cancer patients who underwent CCRT with cisplatin was relatively low when compared to other types of cancer. However, patients with a high Khorana score require more careful surveillance for possible TEE occurrence.
Expression of Interleukin 1, Interleukin 27 and TNF α Genes in Patients with Ischemic Cardiomyopathy Versus Idiopathic Dilated Cardiomyopathy
Authors: Saadi Mahdiyar Iravani , Salami Javad , Abdi Hanieh , Abdolyousefi Ehsan Nabi , Niknam Ahmad , Karimi Zahed , Beigi Mohammad Ali Babaee , Mohammadi Abbas , Manafi Alireza 
Published: February 2021

Abstract
Objective: Congestive Heart failure (CHF) is a complex multifactorial syndrome due to tissue hypo perfusion that is affected by some factors like inflammatory cytokines. In our study we investigated the exact gene expression of three inflammatory cytokines in ischemic and idiopathic cardiomyopathy patients.Materials and Methods: From 49 studied recipients in ischemic group, 23 (46.9%) were male and from 40 studied recipients in idiopathic dilated cardiomyopathy group, 19 (47.5%) were male. For the quantitative analysis of Interleukin (IL)1, IL-27 and TNF-α mRNAs expression level, the SYBR Green Real-Time PCR method was performed using SYBRPremix Ex TaqTM II (Tli RNaseH Plus) (Takara, Japan) and designed primers speciﬁc for each genes in an iQ5 thermocycler (BioRad Laboratories, USA) according to the manufacturer’s instructions.Results: Our results showed that the expression level of IL-1 and TNF-α were significantly higher in the ischemic patients compared to healthy controls (P<0.001, P<0.01, respectively); also we found higher levels of IL-1 and IL-27 gene expressions in idiopathic patients compared to healthy controls (P<0.001, P<0.001, respectively). There were not any significant difference of IL-1, IL-27 and TNF-α expression levels between ischemic patients and idiopathic ones.Conclusion: Although we would introduce IL1, IL-27 and TNF α as effective inflammatory cytokines on myocardial functions in ischemic and idiopathic cardiomyopathy patients; there is not any difference between these two groups in gene expression of three main inflammatory cytokines.