bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exercise-Induce Changes in Hemodynamics, Hormones, Electrolytes and Inflammatory Markers in Veteran Athletes with and without Coronary Atherosclerosis
Authors: Janssen Sylvan L.J.E. , Aengevaeren Vincent L. , de Vries Femke , Kleinnibbelink Geert , Mingels Alma M.A. , Hopman Maria T.E. , Mosterd Arend , Velthuis Birgitta K. , Riksen Niels P. , Eijsvogels Thijs M.H. 
Published: February 2025

ABSTRACT

Aims
Middle-aged and older male athletes have more coronary atherosclerosis than less active peers. We aimed to explore mechanisms that can contribute to this accelerated coronary atherosclerosis by comparing exercise-induced changes in hemodynamic factors, circulating hormones, electrolytes, and inflammatory markers across athletes with and without coronary atherosclerosis.

Methods
59 male athletes recruited from the MARC-2 study were stratified as controls (coronary artery calcium score (CACS) = 0, n = 20), high CACS (≥300 Agatston Units or ≥ 75th MESA percentile, n = 20) or significant stenosis (≥50% in any coronary artery, n = 19). At rest, during an exhaustive endurance cycling test and following 3 hours of recovery, we measured blood pressure and blood concentrations of PTH, calcium, magnesium, phosphate, CRP, IL-6, IL-1RA, IL-10, ICAM-1, VCAM-1, and E-selectin.

Results
58 participants completed the exercise test (76 ± 14 minutes). All biomarkers changed during exercise, except CRP, ICAM-1, and VCAM-1. Systolic blood pressure, PTH, calcium, phosphate, IL-6, IL-1RA and E-selectin concentrations increased during exercise. In contrast, diastolic blood pressure and magnesium concentrations decreased during exercise. The magnitude of exercise-induced responses of hemodynamic factors, circulating hormones, electrolytes, cytokine, and adhesion molecule concentrations did, however, not differ across groups.

Conclusions
Blood pressure, hormone, electrolyte, and cytokine concentrations changed following an exhaustive endurance exercise test, but the magnitude of these responses did not differ between athletes with versus without coronary atherosclerosis. These findings suggest that accelerated coronary atherosclerosis in endurance athletes may not be explained by differences in responses to exercise, but by differences in exercise exposure or other mechanisms not assessed in this study.
Aggressive multiple sclerosis in the Republic of Bashkortostan
Authors: Bakhtiyarova K. Z. , Kuzmina U. Sh. , Lyutov O. V. , Talipova I. D. , Akhmetgaleeva N. F. , Galiullin T. R. , Kutlubaev M. A. 
Published: February 2025

Treatment of patients with aggressive multiple sclerosis (MS) characterized by severe progression of disability within a short period of time is a complex task as there are no uniform criteria for determining such disease progression type and, accordingly, no optimal strategies for prescribing medication. Standardised criteria are also needed to assess prevalence in the general patient population and to plan medical and social care.Objective: to analyse clinical and demographic characteristics of patients with aggressive MS in the Republic of Bashkortostan (RB).Material and methods. The study included 2670 patients registered in the Multiple Sclerosis Centre of the Republic of Bashkortostan. To determine the types of MS progression, criteria of the 2022 clinical guidelines for MS were used. When analysing the data on disability, the data from the control group, which consisted of MS patients without limitations in working capacity and disability, were also used.Results. Rapidly progressive MS (RPMS) and highly active MS (HAMS) were diagnosed in 8.9% of the total number of patients. Women predominated in both groups. In the group of patients with aggressive MS, the progression rate was significantly higher than in the HAMS group. Six percent of patients included in the registry became disabled (group II or I) within 5 years of the disease, and 10% within 10 years. These groups are characterized by a high rate of disease progression.Conclusion. In the RB, RPMS and HAMS were diagnosed in 8.9% of patients, with a predominance of women.
Painful radial nerve neuropathy with focal hourglass-like nerve constriction as a variant of distal neuralgic amyotrophy
Authors: Druzhinina E. S. , Druzhinin D. S. , Rogovskaya Yu. V. , Karapetyan A. S. , Vorobeva S. A. , Zavadenko N. N. 
Published: February 2025

Neuralgic amyotrophy (NA, Parsonage-Turner syndrome) is an autoimmune multifocal painful neuropathy that has a classic pattern of brachial plexus involvement in most patients. Cases in which motor and sensory deficits occur below the elbow joint are classified as a separate form – distal NA. In contrast to the classic pattern of NA, patients with distal NA recover less well and require surgical treatment.Objective: to describe the clinical and instrumental characteristics of patients with focal hourglass-like nerve constriction (FHNC) of the radial nerve.Material and methods. The clinical, electrophysiological and neuroimaging data of 24 patients with painful radial nerve neuropathy (5 women and 19 men, mean age 41.9±15.5 years) were analyzed. The average time from onset of pain to diagnosis was 10.8 months (median 5 months; minimum 4 days, maximum 5 years and 8 months). Glucocorticoids (GC) were taken by 8 patients (33%). Nine patients underwent surgery. The control group consisted of 60 individuals matched for age and gender.Results. All patients complained of neuropathic pain in the affected upper extremity with an average intensity of 9.4 (median 9.5) on the visual analogue scale (VAS). The duration of the pain syndrome was on average 13.4 days (median 12.5 days). According to electromyographic data, all patients showed changes in the muscles of the affected side in the form of chronic denervation. MRI of the nerve trunks in 12 patients, revealed no changes on the affected side in 5 patients (41.6 %). Edema of the nerve trunks was found in 5 patients (41.6%). Muscle atrophy was found in one patient (8.3%) and one patient (8.3%) had FHNC. Comparison of the ultrasound data of the cross-sectional area (CSA) of the affected and unaffected sides showed a significant enlargement of the radial nerve on the affected side (p=0.027); no statistically significant differences were found when comparing the affected and unaffected sides with the control group. FHNC in the radial nerve was found in 19 patients, with both sides affected in two cases. Four patients recovered completely, 3 of them (75 %) received GC and 2 (50 %) underwent surgery. Incomplete recovery was observed in 12 patients (50%). Eight patients (33%) did not recover, of whom only one received GC, while 4 (50%) underwent surgery. Of the patients who underwent surgery, 5 patients (55.6%) recovered completely or partially, 44% did not recover. The mean follow-up time was 10.2±2.9 months.Conclusions. Radial nerve painful neuropathy is a variant of NA whose morphological manifestation is the phenomenon of FHNC detected by ultrasound in the peripheral nerves. The use of ultrasound facilitates the diagnosis of the disease, leading to an earlier diagnosis and consequently to a more favorable prognosis. Surgical treatment should be favored in cases of FHNC.
Understanding premenstrual syndrome: experiences and influences among monastir university students
Authors: Toumi Dhekra , Ben Farhat Imen , Bergaoui Haifa , Ghaddab Imen , Hadj Mohamed Mariam , Aribi Ikram , Sallami Arige , Knaz Samar , Braiek Balsam , Mosbahi Ataa , Gharbi Nedra , Bouakez Sana , Baccouche Fadia , Zoukar Olfa , Hajji Ahmed , Faleh Raja 
Published: February 2025

Abstract
Menstrual health is increasingly recognized as a critical health issue by the World Health Organization, encompassing physical, psychological, and social dimensions. Approximately 1.8 billion women globally experience menstruation, with severe hormonal fluctuations leading to premenstrual syndrome (PMS) and its more severe form, premenstrual dysphoric disorder (PMDD), which significantly affects quality of life. This study investigates PMS symptoms among university students in Monastir (Tunisia) through a descriptive cross-sectional design involving 150 participants. Data was collected via a semi-structured questionnaire, assessing sociodemographic information and PMS symptoms using the validated A-PMS diagnostic tool. Results indicated that 100 % of participants experienced PMS, with 69.3 % reporting moderate to severe physical symptoms such as fatigue and pain, while 65.3 % noted significant psychological symptoms including anxiety and mood swings. Over half of the students reported mild impacts of PMS on relationships and academic performance, with 48 % experiencing absenteeism due to symptoms. Despite the prevalence of symptoms, the majority did not seek medical help. The findings highlight the critical need for educational institutions and healthcare professionals to address PMS and implement support strategies, thereby enhancing the well-being and academic success of young women. This research underscores the importance of raising awareness and developing effective interventions for menstrual health in this population.
Performance analysis of a PPM-OOK based hybrid modulation scheme for Satellite-to-Underwater FSO communication
Authors: Ahmed Syed Abrar , Rani M. S. Divya 
Published: February 2025

Abstract
This paper examines the performance of underwater wireless optical communication (UWOC) links using single-input and single-output (SISO) and selection combining (SC) receiver diversity techniques. To accurately model the effects of underwater turbulence on light propagation, the Malaga gamma (MG) distribution is employed for both weak and strong turbulence conditions. Analytical bit error rate (BER) expressions for on–off keying modulated UWOC links are derived for both SISO and SC receivers, utilizing the MG distribution’s power series representation. Monte Carlo simulations are conducted to validate the analytical BER results. The findings of this study provide valuable insights into the design and optimization of UWOC systems operating in various underwater environments.
Lokale Produktion: ein blinder Fleck?
Authors: Stoltenberg Lisa , Krenz Pascal , Saubke Dominik , Redlich Tobias 
Published: February 2025

Abstract
Um Nachhaltigkeitsziele zu erreichen und die Zukunft unseres Planeten sowie der Menschheit zu sichern, wird zunehmend angestrebt, lineare Wertschöpfungsmodelle durch kreisförmige zu ersetzen. Hierzu existieren verschiedene Strategien, die auch in den nationalen Nachhaltigkeitsplänen verankert sind. Allerdings verfolgen die meisten dieser Strategien das Ziel, Kreisförmigkeit zu erreichen, ohne dabei das Ausmaß dieser Kreise zu berücksichtigen. Ein darüber hinaus gehender Ansatz bestünde darin, die Kreisläufe gleichzeitig zu verkleinern, indem die Wertschöpfung möglichst nah am Ort des Bedarfs stattfindet. Dieser Beitrag setzt sich mit zwei verschiedenen Ansätzen zur Verkleinerung von Wertschöpfungskreisläufen auseinander und zeigt, wie lokale Produktionsnetzwerke sowie die Einbindung der Nutzer:innen in Wertschöpfungsprozesse zu einer Verkleinerung der Wertschöpfungskreisläufe beitragen können.
Evaluation of thyroid ultrasound reports’ quality in the Community of Madrid, Spain
Authors: Valderrabano Pablo , Quiñones Silva Jhonatan Boris , Campos Mena Sandra , Familiar Casado Cristina , de Miguel Novoa María Paz , Sanabria Pérez María Concepción , Fernández Fernández Elisa , López Guerra Aurelio , Sambo Marcel , Martín Rojas-Marcos Patricia , Parra Ramírez Paola , Tasende Fernández Clara , Rodríguez Troyano María Jesús , Alcázar Lázaro Victoria , Lahera Vargas Marcos , Palacios García Nuria 
Published: February 2025

Objective
To evaluate the current quality of thyroid ultrasound reports in the Community of Madrid.

Methods
Consecutive thyroid ultrasound reports from patients evaluated in the endocrine outpatient clinics of eight academic hospitals in the Community of Madrid were assessed for quality during 2021 and 2022. Descriptions of eight different features were evaluated: number and axes of dimensions, composition, echogenicity, margins, shape, calcifications and category of suspicion. Features were considered adequately reported if described for all nodules ≥1 cm. The number of correctly reported features was compared by year of data capture (2021 vs 2022), specialty of the informant (radiologist vs endocrinologist), and origin of the report (in-house vs outsourced center). The quality of reports for assessing the need for cytological evaluation and/or growth during follow-up was evaluated.

Results
A total of 1234 reports were included, 63% from 2021; 82% were issued by radiologists and 89% were issued in-house. Composition and echogenicity were the most frequently reported (79% and 72%, respectively). The rest of the features were appropriately described in less than half of the reports. Forty percent of the reports were good to select nodules for biopsy, 23% had sufficient data to assess growth during follow-up, and only 13% met both quality criteria. The overall quality of reports was worse in outsourced centers (median number of described features 2 vs 4, P < 0.001) and better when issued by endocrinologists (median number of described features 6 vs 3, P < 0.001).

Conclusions
Most thyroid ultrasound reports issued in the Community of Madrid provide insufficient data to make management decisions regarding thyroid nodules.
LA UNIÓN EUROPEA COMO POTENCIA NORMATIVA EN UN MUNDO GLOBALIZADO: ¿SUEÑO O REALIDAD?
Authors: Neves Pérez Hugo 
Published: February 2025

La Unión Europea (UE) es considerada, hoy en día, una potencia normativa. Ha logrado una posición destacada en el comercio internacional y se ha consolidado como uno de los principales mercados a nivel mundial, factores que le han permitido tener una influencia global en términos normativos, logrando que sus normas sean tomadas como modelos de referencia. El papel global de la UE ha sido analizado en base a sus componentes de poder y sus dimensiones de influencia, siendo considerada como una potencia blanda, civil o normativa, debido a su capacidad de influir a través de la persuasión y la atracción en vez de con la coerción. Sin embargo, la influencia de la UE como potencia normativa, en un mundo globalizado y cada vez más incierto, sigue siendo un tema de debate y controversia, ya que algunos cuestionan si realmente la UE tiene la capacidad de influir, de una manera efectiva, en el marco normativo global. Por ello, el propósito de este escrito es dar luz a ese debate, con el objetivo de definir y reflejar el grado de influencia normativa que tiene la UE a nivel internacional.
Az Ötfaktoros Jelentudatosság Kérdőív rövidített, 15 tételes verziójának pszichometriai elemzése magyar mintán
Authors: Rendes Réka , Horváth Diána Ágnes , Deák Anita 
Published: February 2025

Elméleti háttér: A mindfulness (tudatos jelenlét, jelentudatosság) olyan kognitív és érzelmi szempontból összetett jelenség, amely magában foglalja a jelen pillanatra irányuló fenntartott figyelmet, vala-mint a tapasztalatok felé mutatott nyitott, kíváncsi és elfogadó attitűdöt. A mindfulness alapú terápiák rámutatnak arra, hogy a tudatos jelenlét nemcsak egy önmagán belül zajló folyamatot jelöl, hanem egyfajta képességként is definiálható, ennek értelmében pedig gyakorlással fejleszthető. Az egyik leggyakrabban alkalmazott mindfulness képességet vizsgáló mérőeszköz az Ötfaktoros Jelentudatosság Kérdőív (Five Factor Mindfulness Questionnaire, FFMQ). Az eredeti, 39 tételes FFMQ öt dimenzió – Megfigyelés, Leírás, Tudatos cselekvés, Ítélkezésmentesség, Reakciómentesség – mentén ragadja meg a mindfulness jelenségét. Célkitűzés: A kérdőívnek rövidített változatai is születtek, amelyek közül jelen vizsgálat a legrövidebb, az eredeti kérdőív szerzők által leírt 15 tételes változatának (FFMQ-15) adaptációját tűzte ki célul hazai mintán. Módszerek: Az FFMQ-15 magyar nyelvű változatát 117 résztvevő töltötte ki egy kérdőívcsomag részeként. A kérdőívcsomag az FFMQ-15 mellett demográfiai kérdéseket, illetve a konvergens és diszkriminációs validitás mérésére alkalmazott kérdőíveket (Mentális Egészség Kontinuum Skála [MHC-SF], Depresszió, Szorongás és Stressz Skála [DASS-21], Big Five Kérdőív [BFI], Fehér Medve Gondolatelnyomási Kérdőív [WBSI], Érzelemszabályozási Nehézségek Skála [DERS], Kognitív Érzelem-Reguláció Kérdőív [CERQ], Torontói Alexitímia Skála [TAS-20]) tartalmazott. Eredmények: Az FFMQ-15 hierarchikus faktorstruktúrája (5 elsőrendű és 1 másodrendű faktor) konfirmatív faktorelemzéssel megerősítésre került (CFI = 0,976; TLI = 0,967; RMSEA = 0,047; SRMR = 0,084). Az FFMQ-15 konvergens és diszkriminációs érvényességét vizsgálva megállapítható, hogy a tudatos jelenlét képessége a várt irányú kapcsolatot mutatta a mentális egészség (MHC-SF), a depressziós, szorongásos és stressz tünetek (DASS-21), a tapasztalatokra való nyitottság és neuroticizmus (BFI), gondolatelnyomási tendenciák (WBSI) és érzelmi működés (DERS, TAS-20, CERQ) mutatóival. Követ- keztetések: Összességében kijelenthető, hogy az Ötfaktoros Jelentudatosság Kérdőív rövidített 15 tételes verziója alkalmas a mindfulness-képesség egyéni különbségeinek megragadására hazai mintán is.
The head and neck features of Gardner’s Syndrome: A case report and review of the literature
Authors: Black AI , Bunn BK , Motloba PD , Gwengu P 
Published: February 2025

Gardner’s Syndrome represents an autosomal dominant variant of Familial Adenomatous Polyposis in which affected individuals have a 100% risk of developing colorectal carcinoma. The extra-intestinal manifestations in the head and neck region allow for the early recognition and diagnosis of this rare syndrome. The defining triad of features includes intestinal polyposis, dento-osseous anomalies and soft tissue lesions. A 20-year-old female patient presented with a main complaint of swelling involving the left side of her nose, at which time a panoramic radiograph was obtained.Radiographic findings showed multiple osteomas, odontomas, missing teeth as well as unerupted and impacted teeth, the features of which are highly suggestive of Gardner’s Syndrome. Early recognition of the extra-intestinal features of Gardner’s Syndrome warrants patient referral for further investigation including colonoscopy and genetic testing
The orthodontic treatment needs in children aged 12-15 years in a school in Khomas, Namibia: A cross-sectional study
Authors: Serebe  Catherine , Harris Angella , Kimmie-Dhansay Faheema 
Published: February 2025

The aim of this study was to determine the orthodontic treatment needs of a population of 12-15 year old school children and to express it as percentages of those subjective and objective orthodontic treatment need over the whole sample population. There has been a disagreement between normative and subjective need for orthodontic treatment. This is especially true in an African setting.The aim of this cross-sectional study was to determine the orthodontic treatment needs of a population of 12–15-year old children attending a school in Khomas, Namibia. The Modified Index of Orthodontic Treatment Need (IOTN), using the Dental Health Component (DHC) and the Aesthetic Component (AC), was used to determine the normative and subjective need for orthodontic treatment respectively
Resisting Erasure: A Critical Review
Authors: AlAshmar Mohamad 
Published: February 2025

This book review examines The Untold Story of the Golan Heights, which highlights the Jawlani Druze experience under Israeli occupation. The book explores identity, resistance, and survival through a decolonial and interdisciplinary lens, challenging dominant narratives. It offers valuable insights into the region’s complex realities.
تتناول هذه المراجعة كتاب "القصة غير المروية عن هضبة الجولان"، والتي تسلط الضوء على تجربة دروز الجولان تحت الاحتلال الإسرائيلي. يستكشف الكتاب مواضيع الهوية والمقاومة والبقاء من خلال إطار متعدد التخصصات، متحديًا السرديات السائدة. الكتاب يطرح رؤى قيمة حول الحقائق المعقدة في المنطقة.
Reevaluating the depositional model of the Cenomanian–Turonian Bridge Creek Limestone Member near Pueblo, Colorado, U.S.A.: roles of changing sedimentation rate on the formation of limestone–marl bedding couplets
Authors: Li Zhiyang , Flaum Jason 
Published: February 2025

ABSTRACT
Although interbedded limestone–marl couplets in many hemipelagic and pelagic deposits have been commonly attributed to orbital-driven climate cycles, the driving mechanisms of these couplets remain largely controversial. This situation arises from the fact that detailed sedimentologic and petrographic facies characteristics of these fine-grained deposits have rarely been examined closely. In this study we conduct an integrated sedimentologic and petrographic analysis to disentangle causes of the limestone–marl bedding couplets in the Cenomanian–Turonian Bridge Creek Limestone Member (BCL) of the Greenhorn Formation using cores and outcrop near Pueblo, Colorado. By integrating existing geochemical datasets, each of the three general lithologies in the BCL including limestone, marl, and calcareous mudstone can be divided into two facies, a more bioturbated vs. a more laminated facies, in addition to bentonite beds. The variability in sedimentary, bioturbation, and petrographic characteristics of different sedimentary facies types, as well as constraints from the existing orbital time scale, in the BCL indicate changes in sediment accumulation rate or the amount of time recorded by different facies—the limestone, marl, and calcareous facies are interpreted to reflect increasing sedimentation rate. The sedimentary and petrographic facies variations, including but not limited to lithological alternations, in the BCL are interpreted to result from the combined influence of various processes such as bottom currents, bioturbation, early diagenesis, and episodic volcanic input, with some of the above-mentioned processes likely modulated by short-term relative changes in sea level. Results of this study highlight the need for detailed sedimentologic and petrographic studies and consideration of short-term changes in sedimentation rate to fully resolve the causes of the apparent limestone–marl bedding couplets and reliably reconstruct short-term changes in depositional and environmental conditions from the BCL and other similar successions.