bluuebunny/crossref_metadata_2025_split huggingface dataset:
Physical and Psychological Well-being Effects of Cardiac Rehabilitation on Patients Following Mitral Valve and Aortic Valve Procedures
Authors: Jafri S. Hammad , Hushcha Pavel , Dorbala Pranav , Bousquet Gisele , Lutfy Christine , Klein Jodi , Mellett Lauren , Sonis Lindsay , Polk Donna , Skali Hicham 
Published: June 2021

Purpose:
Patients participating in cardiac rehabilitation (CR) following an aortic valve procedure demonstrate improvements in physical capacity and psychological well-being. The primary aim of this study is to evaluate baseline exercise capacity and psychological well-being for mitral valve patients participating in CR and to compare physical and psychological outcomes between mitral valve and aortic valve patients.

Methods:
The primary endpoint was improvement in 6-min walk test (6MWT) distance. Secondary endpoints included change in exercise min/wk, depression scores (Patient Health Questionnaire-9 [PHQ-9]), anxiety scores (General Anxiety Disorder-7 [GAD-7]), and overall quality of life (Dartmouth Cooperative Functional Assessment [COOP]) scores.

Results:
Between January 2015 and December 2019, 94 patients who underwent an aortic valve procedure and 46 patients who underwent mitral valve procedures were enrolled prospectively in CR. At the completion of their CR program, patients had similar improvements in their 6MWT (mitral valve: 173 ft [125, 238] vs aortic valve 197 ft [121, 295], P = .42); exercise min/wk (mitral valve: 90 min [45, 175] vs aortic valve: 80 min [40, 130], P = .44). Changes in anxiety (GAD-7), depression (PHQ-9), and COOP scores were smaller but similar between the two groups.

Conclusions:
CR participation resulted in similar improvements in physical activity between patients undergoing mitral valve and aortic valve procedures. Psychological well-being and quality of life scores improved minimally and similarly between the two groups.
Maternal thrombin generation and D-dimer levels in obesity and pregnancy: results from the maternal thrombin generation in obesity and pregnancy (MaTOPs) study
Authors: Mandlebe Batsho , Orundami Oyindasola I. , Lynch Lee-Anne , Teale Glyn , Said Joanne M. , Cutts Briony A. 
Published: June 2021

Venous thromboembolic disease (VTE) risk increases five-fold antenatally and 14-fold during the puerperium. Obesity significantly increases this risk. The D-dimer assay and more novel Calibrated Automated Thrombogram (CAT) assay laboratory tests display potential for use in VTE risk stratification in pregnancy, although to date, research in the performance characteristics of these tests in obese and nonobese pregnant populations is limited.
The aim of this study was to compare D-dimer and thrombin generation levels in obese and nonobese pregnant women.
Pregnant women were recruited and categorised, as obese (BMI ≥30) or nonobese (BMI 18.5-25). Blood was collected at 26–28 weeks’ gestation, 36–40 weeks’ gestation and 6–12 weeks postpartum and D-dimer concentrations and endogenous thrombin potential (ETP) were determined. Student's t-test was used to analyse differences in mean D-dimer and ETP.
At 36–40 weeks, obese pregnant women had higher D-dimer concentrations (P = 0.001) but lower ETP levels compared with nonobese women (P = 0.044). D-dimer was higher in nonobese than in obese women at 6–12 weeks postpartum (P = 0.026). There was no difference in mean D-dimer (P
= 0.825) and mean ETP (P
= 0.424) between obese and nonobese women at 26–28 weeks. No difference was observed in mean ETP at 6–12 weeks postpartum (P
= 0.472). ETP was lower in both obese and nonobese women postpartum than during pregnancy. D-dimer was lower in obese women but not in nonobese women postpartum.
D-dimer concentrations and ETP were not significantly different during multiple time points in pregnancy and postpartum between obese and nonobese pregnant women suggesting limited utility in VTE risk assessment in obese pregnant women.
Oncostatin-M Does Not Predict Treatment Response in Inflammatory Bowel Disease in a Pediatric Cohort
Authors: Ezirike Ladipo Jennifer , He Zhaoping , Chikwava Kudakwashe , Robbins Katherine , Beri Jonathan , Molle-Rios Zarela 
Published: June 2021

ABSTRACT

Objectives:
This study aimed to determine whether mRNA expression of oncostatin-M (OSM) and its receptor (OSMR) in initial, pre-treatment intestinal biopsies is predictive of response to tumor necrosis factor antagonists (anti-TNF) in a pediatric inflammatory bowel disease (IBD) cohort. Secondary outcomes correlated OSM and OSMR expression with demographic variables; IBD type, extent, phenotype, and severity; laboratory values; and endoscopic findings.

Methods:
A retrospective chart review was conducted on 98 pediatric patients. Patients’ clinical courses were stratified as follows: failed anti-TNF (n = 14), quiescent on anti-TNF (n = 36), anti-TNF naïve (n = 19), and age-matched non-IBD controls (n = 29). The mRNA from each patient's pre-treatment ileal or colonic biopsy was isolated, and expression of OSM and OSMR was analyzed.

Results:
There was no difference in OSM or OSMR expression among the three IBD groups; however, expression was significantly higher in patients with IBD than non-IBD controls (P < 0.001). OSM and OSMR were more highly expressed in patients with ulcerative colitis (UC) with a Mayo score of 3 (P = 0.0092 and P = 0.0313, respectively). High OSM expression correlated with severe disease activity indices at diagnosis (P = 0.002), anemia at diagnosis (P = 0.0236), and need for immunomodulators (P = 0.0193) and steroids (P = 0.0273) during patients’ clinical courses.

Conclusions:
OSM and OSMR expression were not predictive of response to anti-TNF in our pediatric cohort. OSM expression did correlate with IBD compared with healthy controls as well as with several clinical indicators of severe IBD.
Dissemination of bla OXA-48 like, bla NDM, bla KPC , bla IMP-1, bla VIM genes among carbapenem-resistant Escherichia coli and Klebsiella pneumoniae strains in Southeastern Turkey: first report of Klebsiella pneumoniae co-producing bla OXA-48-like, bla VIM and bla IMP-1 genes
Authors: Alkan Bilik Özge , Bayraktar Mehmet , Özcan Nida , Gül Kadri , Akpolat Nezahat 
Published: June 2021

Introduction:
Carbapenem-resistant Enterobacterales (CRE) cause serious and life-threatening infections with limited treatment options. The most common causes of carbapenem resistance are carbapenemases. We aimed to determine the most prevalent carbapenemase genes; bla
NDM
, bla
KPC
, bla
IMP-1, bla
VIM
, bla
OXA-48 like genes among Klebsiella pneumoniae and Escherichia coli strains in the southeast region of Turkey.

Methods:
Eighty-nine isolates (74 K. pneumoniae, 15 E. coli) were included in the study. The isolates were found as carbapenem-resistant by BD Phoenix automated system and Kirby Bauer disk diffusion test. Antibiotic susceptibility testing was performed by BD Phoenix automated system. Combination disc method (CDM) was also carried out as phenotypic method of carbapenemase detection. The presence of bla
NDM
, bla
KPC
, bla
IMP-1, bla
VIM and bla
OXA-48-like genes were investigated by Xpert CARBA-R (Cepheid, USA) multiplex PCR commercial system.

Results:
Antibiotic resistance rates by Phoenix were 48.3 97.8, 80.9, 96.6, 93.3, 96.6, 97.8, 69.7 and 97.8% for amikacin, aztreonam, cefepime, ceftazidime, ciprofloxacin, levofloxacin, moxifloxacin, trimethoprim sulfamethoxazole and piperacillin-tazobactam, respectively. The bla
OXA-48-like gene was detected in 65 (73%); bla
NDM gene in 4 (4.5%); co-production of bla
OXA-48-like and bla
NDM in 6 (6.7%); co-production of bla
OXA-48-like, bla
VIM and bla
IMP-1 genes in 1(1.2%) isolate. None of the bla
OXA-48-like, bla
NDM
, bla
VIM
, bla
IMP-1, bla
KPC genes were detected in 13 (14.6%) of the isolates. The sensitivity and specificity of CDM were calculated as 80 and 85% respectively.

Conclusion:
We detected bla
OXA-48-like gene most frequently in our region. To our knowledge, this is the first report of K. pneumoniae-co-producing bla
OXA-48-like, bla
VIM and bla
IMP-1 genes. The coexistence of these genes is alarming and causes both infection control and treatment problems. Effective infection control measures are essential to prevent the spread of antibiotic resistance.
Experiencing Bullying Is Associated With Firearm Access, Weapon Carriage, Depression, Marijuana Use, and Justice Involvement in Adolescents
Authors: Donnelly Katie A. , Rucker Alexandra , Boyle Meleah D. , Fornari Marci J. , Badolato Gia M. , Goyal Monika K. 
Published: June 2021

Objectives
The aims of this study were to assess whether bullying experience among youths is associated with firearm access and to evaluate assault perpetration risk factors between bullied and nonbullied adolescents.

Methods
This was a secondary analysis of a cross-sectional survey designed to measure self-reported social determinants of health and behavioral health risks among adolescents (13–21 years) in a pediatric emergency department between July 2017 and August 2019. Participants were included in this subanalysis if they responded to a survey item that assessed bullying. Multivariable logistic regression was used to measure the association of firearm access, weapon carriage, and assault perpetration factors (violence, mental health, substance abuse, and justice involvement) with bullying after adjustment for sex, race/ethnicity, and insurance status.

Results
Of the 369 participants meeting inclusion criteria, 147 adolescents (40.5%) reported experiencing bullying. Bullied teenagers had higher odds of a gun in the home (adjusted odds ratio [aOR], 3.0; 95% confidence interval [CI], 1.2–7.8]), weapon carriage (aOR, 5.6; 95% CI, 1.6–18.8), witnessing an assault (aOR, 3.0; 95% CI, 1.6–5.6), negative experience with law enforcement (aOR, 4.5; 95% CI, 2.2–9.2), mental health diagnosis (aOR, 3.9; 95% CI, 2.3–6.7), and marijuana use (aOR, 2.7; 95% CI, 1.1–7.0]).

Conclusions
More than 1 in 3 adolescents presenting to the emergency department report having ever experienced bullying. Bullied teenagers have a higher likelihood of firearm access, weapon carriage, and violent injury perpetration risk factors compared with nonbullied youths. Further studies are needed to understand the relationship between bullying and assault perpetration.
Ultrafast Light Targeting for High-Throughput Precise Control of Neuronal Networks
Authors: Faini Giulia , Molinier Clément , Telliez Cécile , Tourain Christophe , Forget Benoît C. , Ronzitti Emiliano , Emiliani Valentina 
Published: June 2021

ABSTRACTUnderstanding how specific sets of neurons fire and wire together during cognitive-relevant activity is one of the most pressing questions in neuroscience. Two-photon, single-cell resolution optogenetics based on holographic light-targeting approaches enables accurate spatio-temporal control of individual or multiple neurons. Yet, currently, the ability to drive asynchronous activity in distinct cells is critically limited to a few milliseconds and the achievable number of targets to several dozens. In order to expand the capability of single-cell optogenetics, we introduce an approach capable of ultra-fast sequential light targeting (FLiT), based on switching temporally focused beams between holograms at kHz rates. We demonstrate serial-parallel photostimulation strategies capable of multi-cell sub-millisecond temporal control and many-fold expansion of the number of activated cells. This approach will be important for experiments that require rapid and precise cell stimulation with defined spatio-temporal activity patterns and optical control of large neuronal ensembles.
Performance comparison of modified elephant herding optimization tuned MPPT for PV based solar energy systems
Authors: Subramanian Annapoorani , R. Jayaparvathy 
Published: June 2021

Purpose
The solar photovoltaic (PV) system is one of the outstanding, clean and green energy options available for electrical power generation. The varying meteorological operating conditions impose various challenges in extracting maximum available power from the solar PV system. The drawbacks of conventional and evolutionary algorithms-based maximum power point tracking (MPPT) approaches are its inability to extract maximum power during partial shading conditions and quickly changing irradiations. Hence, the purpose of this paper is to propose a modified elephant herding optimization (MEHO) based MPPT approach to track global maximum power point (GMPP) proficiently during dynamic and steady state operations within less time.

Design/methodology/approach
A MEHO-based MPPT approach is proposed in this paper by incorporating Gaussian mutation (GM) in the original elephant herding optimization (EHO) to enhance the optimizing capability of determining the optimal value of DC–DC converter’s duty cycle (D) to operate at GMPP.

Findings
The effectiveness of the proposed system is compared with EHO based MPPT, Firefly Algorithm (FA) MPPT and particle swarm optimization (PSO) MPPT during uniform irradiation condition (UIC) and partial shading situation (PSS) using simulation results. An experimental setup has been designed and implemented. Simulation results obtained are validated through experimental results which prove the viability of the proposed technique for an efficient green energy solution.

Originality/value
With the proposed MEHO MPPT, it has been noted that the settling period is lowered by 3.1 times in comparison of FA MPPT, 1.86 times when compared to PSO based MPPT and 1.29 times when compared to EHO based MPPT with augmented efficiency of 99.27%.
An assessment of the roles of tenure and inclusion in conflict mediation at Cabo Pulmo National Park, Mexico
Authors: Mooney Henry N. , Cárdenas Jr Miguel A. , Cárdenas Miguel A. 
Published: June 2021

PurposeThis study aims to unify phenomena in academic and grey literature into a theory of marine spatial disappropriation based on geopolitical relationships. It is argued that conflict over marine space arises as a result of top-down sovereign control of marine resources, and that the recognition of marine tenure and greater inclusivity in marine development* decision-making would lessen conflict between users, such as artisanal fishermen and ecotourism businesses.Design/methodology/approachA preliminary literature review was conducted, followed by a research study at Cabo Pulmo National Park (CPNP) in Baja California Sur, Mexico.FindingsThe results demonstrate that though CPNP's tenure structure is unique and inclusivity is an element of its management, the degree to which it is practiced is not sufficient to eliminate the chance of eventual disappropriation and ensuing conflict.Practical implicationsThe results of this assessment can be used to strengthen the argument in favour of developing stronger requirements for deliberative democratic decision-making in marine delineation, as well as bolder social performance standards in marine development industries.Originality/valueResearch on socio-environmental revolutions are not new, but the authors contest that they are not alone a sufficient condition for achieving reduced conflict long-term. Instead, the originality of this research lies in its exploration of the importance of customary and formal tenure over marine resources, and its suggestion that this on the whole reduces conflict between exclusive and competing interests. One popular alternative, as demonstrated in numerous cases around the globe, can often be the marginalization of small-scale ocean users through the forceful appropriation of ocean resources.
Abusive supervision and its relationship with knowledge hiding: the mediating role of distrust
Authors: Farooq Rayees , Sultana Almaas 
Published: June 2021

PurposeThe purpose of this study is to analyze the relationship between abusive supervision and knowledge hiding. The study also examines the mediating role of distrust in the relationship between abusive supervision and knowledge hiding.Design/methodology/approachThe procedure used in the study is a systematic literature review covering abusive supervision, knowledge hiding, distrust from 1994 to 2021. The studies were explored using the keyword search such as, “abusive supervision,” “knowledge hiding” and “distrust” from the selected databases including Emerald, ScienceDirect, EbscoHost and Google Scholar.FindingsThe study found that abusive supervision is positively related to knowledge hiding and distrust mediates the relationship between abusive supervision and knowledge hiding. The study also proposes procrastination as one of the dimensions of knowledge hiding.Originality/valueThe study is an attempt to uncover a series of relationships between abusive supervision, knowledge hiding and distrust, which may enhance academic discussion and also offer clarity to the conceptualization of these two fields.
The impact of simultaneous holdings of equity and debt on financial covenants in debt contracts
Authors: Lee Sungsil 
Published: June 2021

Purpose
The purpose of this study is to examine the effects of non-commercial banking institutions’ simultaneous holdings of equity and debt in the same firm (hereafter, dual holdings) on financial covenants in debt contracts.

Design/methodology/approach
By using the DealScan database, this study tests how dual holdings affect the number of financial debt covenants.

Findings
This study finds that the presence of dual holders is positively associated with the number of financial covenants in general, suggesting that the use of financial covenants is reduced when the interests between shareholders and creditors are aligned. This study also finds that dual holder participation does not reduce the number of financial covenants in leveraged loans as much as it does in investment-grade loans. Additionally, when a dual holder has a large portion of equity stakes and loan claims in a borrowing firm, the effect of dual holdings on financial covenants is more pronounced.

Originality/value
This study contributes to debt market research by showing that dual holder participation reduces the number of financial covenants in debt contracts.
Executives’ observance of zakat among Islamic financial institutions: evidence from Bahrain and Malaysia
Authors: Poon Jessie P.H. , Chow Yew Wah , Ewers Michael , Hamilton Trina 
Published: June 2021

PurposeThe purpose of this paper is to examine the influence of Shariah board members and managerial networking on zakat observance among executives of Islamic financial firms (IFFs) in Bahrain and Malaysia.Design/methodology/approachThe methodology is based on surveys administered to 106 respondents and personal interviews conducted with individuals holding management positions in IFFs.FindingsThe paper finds that: networking among IFF executives in Bahrain positively influences their observance and perception of zakat in their firms; and higher representation of Shariah on the board of directors increases executives’ favorable perception and observance of zakat in Malaysia. Differences in findings may be explained by Bahrain’s global Shariah institutions where networking offers opportunities for socialization of zakat ethics. In Malaysia, on the other hand, Shariah directorship sets the pace and direction of zakat ethics.Originality/valueThe seminal work of DiMaggio and Powell (1991) on neo-institutional theory has drawn attention to executives’ agency in creating cognitive frameworks that help promote the development of firm standards and norms. However, application of the theory to Islamic finance is largely absent. This paper contributes to an empirical understanding of the theory by highlighting sources of IFFs’ social agency in the development of zakat norm and its observance, namely, managerial networking and Shariah directors as change agents.
A fuzzy approach to assess outsourcing risks in Brazilian navy industrial military organizations
Authors: Vieira Luiz Fernando do Nascimento , Caetano Igor dos Santos , Santos Ricardo França 
Published: June 2021

Purpose
This study assesses outsourcing risks using the fuzzy analytical hierarchy process (FAHP).

Design/methodology/approach
This descriptive research combines both qualitative and quantitative approaches. Risks identified in the literature review were classified with FAHP using questionnaire data from respondents in operations, procurement and risk management in Brazilian Navy Industrial Military Organizations (OMPS-I, by its Portuguese acronym).

Findings
The results indicate that FAHP is a method capable of producing relevant information to decision-making in the risk management process. A framework was created incorporating 16 major risks related to outsourcing. The results point to higher inherent risk levels related to outsourcing in the context of OMPS-Is: in order, hidden costs and unrealized savings; loss of knowledge/skills and/or corporate memory and difficulty in reacquiring a function; and loss of opportunities and reputation. The category of economic risk was revealed as the most important.

Originality/value
This study improves understanding of outsourcing risks and improves risk assessment by refining decision-making information and developing a system of decision analysis with several criteria. It also contributes to the development and implementation of a usable version of decision analysis with several criteria at a managerial level.
Effects of heat transfer and the endoscope on Jeffrey fluid peristaltic flow in tubes
Authors: Abd-Alla A.M. , Abo-Dahab S.M. , Abdelhafez M.A. , Thabet Esraa N. 
Published: June 2021

PurposeThis article aims to describe the effect of an endoscope and heat transfer on the peristaltic flow of a Jeffrey fluid through the gap between concentric uniform tubes.Design/methodology/approachThe mathematical model of the present problem is carried out under long wavelength and low Reynolds number approximations. Analytical solutions for the velocity, temperature profiles, pressure gradient and volume flow rate are obtained.FindingsThe results indicate that the effect of the wave amplitude, radius ratio, Grashof number, the ratio of relaxation to retardation times and the radius are very pronounced in the phenomena. Also, a comparison of obtaining an analytical solution against previous literatures shows satisfactory agreement.Originality/valueAnalytical solutions for the velocity, temperature profiles, pressure gradient and volume flow rate are obtained. Numerical integration is performed to analyze the pressure rise and frictional forces on the inner and outer tubes.