bluuebunny/crossref_metadata_2025_split huggingface dataset:
Studio comparativo delle parole composte e polirematiche nel linguaggio medico italiano e polacco
Authors: Maniowska Katarzyna 
Published: October 2021

Dardano ricorda che nella terminologia medica italiana “la componente latina e greca costituisce un patrimonio cospicuo” (Dardano 501, 514). Lo stesso si può dire per il polacco, sebbene gli elementi greco-latini usati nel linguaggio medico siano molto spesso accompagnati dai loro sinonimi di origine slava. Mentre in italiano i termini come condromatosi, faringoplastica o nefropatia fanno parte sia del linguaggio tecnico che divulgativo, in polacco si osservano coppie terminologiche come: chondromatoza – chrzęstniakowatość, faryngoplastyka – plastyka gardła, nefropatia – choroba nerek, usate a seconda della situazione comunicativa e del registro.
In italiano, in molti casi, è possibile formare sintagmi preposizionali e aggettivali come: ernia del disco/ernia discale, exeresi dei linfonodi/exeresi linfonodale. La costruzione con il complemento di specificazione, sebbene ammissibile in certi casi, non sembra adeguata al registro alto del linguaggio specialistico. I termini corrispondenti in polacco avranno invece una sola variante con il complemento di specificazione: przepuklina kręgosłupa, usunięcie węzłów chłonnych.
Lo studio comparativo delle parole complesse e polirematiche esistenti nella terminologia medica polacca e italiana permetterà di individuare eventuali differenze nei due sistemi linguistici e indicarne le funzioni sintattico-semantiche.
The Effects of Physical Activity on Physeal and Skeletal Development
Authors: Carsen Sasha , Grammatopoulos George , Zaltz Ira , Ward Leanne , Smit Kevin , Beaulé Paul E. 
Published: October 2021

» There is increasing evidence in the literature regarding the important health impact of and risk factors for injury in youth sport.» Increasing pediatric and adolescent activity intensity, such as is seen in earlier single-sport focus and specialization, may be associated with morphological changes in the growing skeleton.» Chronic subacute injury to the developing physes in the active child can lead to stress on the growth plate and surrounding tissues that induces developmental morphological changes in the joint.» There is evidence to suggest that frequent participation in sports that place particular stress across the physes of the proximal humerus, the proximal femur, and the distal radius can be associated with an increased risk of inducing developmental and morphological changes that could lead to future joint dysfunction and premature degeneration.» Additional research is necessary to better define the pathoetiology of activity-mediated morphological changes, as well as to create and validate parameters for safe involvement in competitive physical activities.
Efficacy of Antimicrobial Photodynamic Therapy Compared to Nystatin Therapy in reducing Candida Colony Count in Patients with Candida-Associated Denture Stomatitis: A Systematic Review and Meta-analysis
Authors: Firoozi Parsa , Farshidfar Nima , Fekrazad Reza 
Published: October 2021

Abstract
Purpose: This meta-analysis assessed the efficacy of antimicrobial photodynamic therapy (aPDT) compared to conventional nystatin therapy (NYT) in reducing Candida colony count in patients with Candida-Associated Denture Stomatitis (CADS) and critically appraised the available literature.Methods: This meta-analysis was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) updated guidelines. A literature search was performed in four electronic databases to identify relevant articles up to 15 August 2021. Randomized controlled trials (RCTs) that assessed the efficacy of aPDT compared to NYT in reducing Candida colony count in patients with CADS were investigated. The weighted mean difference (MD) and 95% confidence interval were calculated. The I2 statistic was used to determine heterogeneity at the level of α= 0.10. The Cochrane risk of bias (RoB 2) tool was used to assess the risk of bias. Certainty of the evidence was determined using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) ranking system.Results: Only 3 eligible RCTs with 141 participants were included in this systematic review and meta-analysis. Based on the pooled results, NYT compared to aPDT, generally performed better in reducing Candida colony count (Log10 CFU/mL) in patients’ palate and patients’ denture. The included studies had a moderate risk of bias and the certainty of the evidence was low.Conclusion: Although still inconclusive, based on the current evidence aPDT may be effective in reducing Candida colony count, and treating CADS. Nonetheless, it does not appear to be more effective than conventional NYT in this regard. According to the limited number of included studies, more well-designed RCTs with larger sample sizes and standardized methodology should be conducted to validate this conclusion.
Custodiol HTK Versus Plegisol: in-Vitro Comparison With The Use of Immature (H9C2) and Mature (HCM) Cardiomyocytes Cultures
Authors: Nowicki Rafał , Berezowski Mikołaj , Kulbacka Julita , Bieżuńska-Kusiak Katarzyna , Jasiński Marek , Saczko Jolanta 
Published: October 2021

Abstract
Background: Although cardioplegia is used since the ‘70s of the last century, debate on cardioprotection during cardio-surgical procedures is still actual. The selection of a particular method depends mainly on the preferences and experience of a specific center or even surgeon. Crystalloid cardioplegia is an aqueous ion solution similar to intracellular (Custodiol HTK) or extracellular (Plegisol) fluid. Numerous publications compare different types of cardioplegic solutions, but only a few used cultured cells in laboratory conditions. Methods: In this study, the authors compare two crystalloid solutions using an in-vitro model simulating cardioplegic arrest. The efficacy of myocardial protection during ischemia was investigated with susceptible indicators like the appearance of the deleterious effect of reactive oxygen species and oxidative stress markers. Incubated human cardiomyocytes and rat cardiomyoblasts H9C2 in cardioplegia for 4h were examined for expression of oxidative stress markers (MnSOD, iNOS, HSP27), cardioplegic solutions cytotoxicity, and peroxidation damage of the cell’s lipids and proteins. All tests were performed after 0.5h, 1h, 2h, and 4h in identical physical and biological conditions, which is difficult to achieve in clinical trials. Results: The tests performed on matured cells of human cardiomyocytes showed the superiority of Custodiol HTK. Differences between solutions on immature cells H9C2 were not relevant. Both Plegisol and Custodiol HTK produced a similar expression of MnSOD and iNOS. There was no significant advantage of Custodiol over Plegisol in the cytotoxicity test. However, Custodiol induced a higher level of lipid peroxidation. Conclusions: Considering proceeded examinations on cultured cardiomyocytes, Custodiol HTK appears to be safer than Plegisol.
Exploring The Relationship Between Support, Confidence, Coping Skills and Burnout in Residential Aged Care Staff
Authors: Low Yin Siu (Jane) , Bhar Sunil , Chen Won Sun (Sharon) 
Published: October 2021

Abstract
Background and Objectives: Staff working in residential aged care facilities (RACFs) face unique challenges and stressors in their workplaces which increase their risk for occupational burnout. Burnout in this workforce results in low job satisfaction, increased levels of absenteeism and poor retention rates. Given Australia’s ageing population and the demand for residential aged care (RAC) staff, it is imperative to explore predictors of burnout in this cohort in order to help staff prevent and manage burnout.Research Design and Methods: This study examined the extent to which support, confidence and adaptive coping skills predicted burnout among RAC staff, after controlling for staff demographics, organisational climate and work patterns. One hundred and thirty three RAC staff across Australia were surveyed using online questionnaires measuring levels of support, confidence, adaptive coping skills and burnout. Results: Regression analyses indicated that, overall, support, confidence, and adaptive coping predicted each dimension of burnout (emotional exhaustion, depersonalization and personal accomplishment). After controlling for covariates and other predictors: confidence significantly predicted all three dimensions; support significantly predicted emotional exhaustion and depersonalization, and adaptive coping significantly predicted emotional exhaustion.Discussion and Implications: These findings suggest that support, confidence and adaptive coping skills need to be addressed to prevent and manage occupational burnout for RAC staff in Australia.
Induction, identification, and characterization of autoallo-dodecaploid barnyard grass (Echinochloa crus-galli L.) using in vitro colchicine treatment
Authors: Yang Xiaolu , Wang Wei , Zhou Xiaoling , Feng Ziyi , Lv Pincang , Wang Jie , Zhang Xianhua , Zhu Wangwen , He Yuchi , Song Zhaojian , Cai Detian 
Published: October 2021

Abstract
Polyploidization is a major trend in plant evolution that has many advantages over diploid. Barnyard grass (Echinochloa crusgalli L.) has many good characteristics, but has not been fully utilized until now. In this study, we report for the first time the in vitro induction of autoallo-dodecaploid E. crus-galli by colchicine treatment. Calli derived from young panicles were transferred to liquid medium containing different concentrations of colchicine (0.01, 0.05, or 0.1% w/v) and incubated for 24, 48, or 72 h. Treatment with 0.05% colchicine for 48 h was the most effective condition for producing polyploid plants, yielding 42.9% dodecaploids. The relative DNA content of the induced dodecaploids was twice that of wild-type hexaploids. The chromosome number of dodecaploids was 2n = 12x = 108, whereas that of hexaploids was 2n = 6x = 54. Compared with the hexaploids, the dodecaploids had larger individual stomata, but a lower stomatal density. There were significant differences between dodecaploid and hexaploid plants in terms of morphological variables, such as plant height, leaf length, panicle length, and grain size. Dodecaploid plants showed the obvious “gigas” effects of polyploid organs, as well as significantly reduced seed set. The nutritional concentrations of crude protein, crude fat, crude ash, and nitrogen-free extract in the dodecaploid were higher than those in the hexaploid, whereas the concentration of crude fiber in the dodecaploid was lower. Compared with the hexaploid, the concentrations of calcium, iron and some free amino acids in dodecaploid plants were significantly higher than in hexaploids. The dodecaploid E. crus-galli had been obtained successfully by treating calli with colchicine. And E. crus-galli has the potential to be developed as a new type of high quality forage crop for cultivation under stress conditions, especially the dodecaploid with its greater nutritional value.
Transcriptional Expressions of SCNs Family Correlates With Overall Survival in Patients With Breast Cancer
Authors: Peng Wenxing , Shi Xiujin , Zhang Yi , Zhao Honglei , Zhang Yunnan , Han Jialun , Qiao Huanyu , Lin Yang 
Published: October 2021

Abstract
Background: Voltage-gated sodium (Nav) channels encoded by SCNs are heteromeric protein complexes containing pore-forming α subunits together with non-pore-forming β subunits. Ion channels play an important role in the regulation of many cellular processes during normal physiology, and increasingly recognized for their contribution to pathophysiology, including cancers. Numerous studies in the last years have reported the expression of SCNs in metastatic cells of many cancers and their upregulation have been evident in promoting migration, invasion and metastasis, whereas it remains unclear whether distinct SCNs family members play an important role in the development and progression of BC. Results: The study investigated the roles of SCNs in the prognosis of BC using ONCOMINE, UALCAN, Kaplan-Meier Plotter, GEPIA, Metascape, LinkedOmics databases. The results showed that transcriptional and proteinic expressions of 9 SCNs were downregulated in patients with BC, including SCN1A~4A, 7A, 9A and SCN2B~4B. low expressions of 11 SCNs members were found to be significantly associated with poorer overall survival (OS) in BC patients (P＜0.01), including SCN2A, 3A, 5A, 7A, 9A~11A and SCN1B~4B. Moreover, prognostic value of mRNA expression of SCNs could only be seen in HER2-negative BC patients when we performed subgroup analysis. Conclusions: These results indicated that SCNs could be prognostic biomarkers for survivals of BC patients. Some medicines that regulate SCNs might provide new targets for BC treatment.
Silicon Changes C:N:P Stoichiometry and Favors Pre-Sprouted Seedling Growth, Yield and the Technological Quality of Sugarcane.
Authors: Albiasetti Tálisson , Júnior Jonas Pereira Souza , Prado Renato Mello , Frazão Joaquim José , Piccolo Marisa de Cássia 
Published: October 2021

Abstract
The importance of silicon (Si) in sugarcane is well known, but its effects on changing C:N:P stoichiometry enough to increase pre-sprouted seedling (PSS) and sugarcane development in the field remains unknown. To that end, the present study aimed to assess whether Si fertigation favors its absorption enough to change elemental stoichiometry (C:N:P), physiological attributes and PSS growth, as well as the growth, stem yield and juice quality of sugarcane. Two field experiments were conducted in the PSS formation stage and another in the sugarcane plant development phase. Experiment 1 was carried out in a greenhouse with PSSs under two treatments: in the absence and presence of Si (2 mmol L−1) fertigation. Experiment 2 was performed in the field in red-yellow argisol with the sugarcane plant undergoing the following treatments: absence of Si (No Si); Si supplied by fertigation during the PSS formation and sugarcane plant development phases (Si–C); and Si supplied during the PSS formation and sugarcane plant development phases (Si–M+C). The following were assessed in experiment I: growth, leaf green color index (GCI), chlorophyll fluorescence, C, N, P, and Si content, and C:Si, C:N and C:P stoichiometric ratios. In experiment II, the same stoichiometric ratios were assessed, as well as sugarcane growth, stem yield and juice quality. Si reduced the C:Si, C:N and C:P stoichiometric ratios in PSS. The C:Si ratio in the leaves and stems declined with the supply of Si, while the C:N and C:P ratio in the leaves and stem was higher in plants that received Si in the Si-M+C treatment. Applying Si fertigation in PSS formation to promote changes in C:N:P stoichiometry favored photosynthetic efficiency and growth. The Si–M+C treatment stood out, since it also caused enough C:N:P stoichiometric changes to increase sugarcane growth, yield and juice quality.
Magnetically tightened form-stable phase change materials with modular assembly and geometric conformality features
Authors: Lu Yongyu , Yu Dehai , Dong Haoxuan , Lv Jinran , Wang Lichen , Zhou He , Liu Jing , He Zhi-Zhu 
Published: October 2021

Abstract
Recently, phase change materials (PCMs) have attracted significant attention due to their promising applications in many fields like solar energy and chip cooling. However, the present PCMs seriously suffer inevitable leakage and low thermal conduction. Magnetism can produce invisible field effects in the surrounding space. If there exist magnetic particles within this region, the effects will act on them emerging various fascinating phenomena. Inspired by this, we introduce hard magnetic particles (which can keep the effect after removing the magnetic field) to PCMs synthesizing an unprecedented magnetically tightened form-stable PCMs (MTPCMs), achieving multifunctions of leakage-proof, dynamic assembly and morphological reconfiguration, superior high thermal (increasing of 1400%~1600%) and electrical (>104 S/m) conductivity, and prominent compressive strength. Novel free-standing temperature control and high-performance thermal and electric conversion systems based on MTPCMs are furthermore developed. This work is a significant step toward exploiting a smart PCM for electronics and low-temperature energy storage.
Electroencephalography in Delirium Assessment. A Scoping Review
Authors: Wiegand Tim , Rémi Jan , Dimitriadis Konstantinos 
Published: October 2021

Abstract
BackgroundDelirium is a common disorder affecting up to 82% of patients in the intensive care unit (ICU). Delirium assessment scores such as the Confusion Assessment Method (CAM) are time-consuming, they cannot differentiate between different types of delirium and their etiologies, and they may have low sensitivities in the clinical setting. While today, electroencephalography (EEG) is increasingly being applied to delirious patients in the ICU, a lack of clear cut EEG signs, leads to inconsistent assessments. MethodsWe therefore conducted a scoping review on EEG findings in delirium. 1236 articles identified through database search on PubMed and Embase were reviewed. Finally, 33 original articles were included in the synthesis. ResultsEEG seems to offer manifold possibilities in diagnosing delirium. All 33 studies showed a certain degree of qualitative or quantitative EEG alterations in delirium. Thus, normal routine (rEEG) and continuous EEG (cEEG) make presence of delirium very unlikely. All 33 studies used different research protocols to at least some extent. These include differences in time points, duration, conditions, and recording methods of EEG, as well as different patient populations, and diagnostic methods for delirium. Thus, a quantitative synthesis and common recommendations are so far elusive. ConclusionFuture studies should compare the different methods of EEG recording and evaluation to identify robust parameters for everyday use. Evidence for quantitative bi-electrode delirium detection based on increased relative delta power and decreased beta power is growing and should be further pursued. Additionally, EEG studies on the evolution of a delirium including patient outcomes are needed.
MEMSORN: Self-organization of an inhomogeneous memristive hardware for sequence learning
Authors: Payvand Melika , Moro Filippo , Nomura Kumiko , Dalgaty Thomas , Vianello Elisa , Nishi Yoshifumi , Indiveri Giacomo 
Published: October 2021

Abstract
Learning is a fundamental component for creating intelligent machines. Biological intelligence orchestrates synaptic and
neuronal learning at multiple time-scales to self-organize populations of neurons for solving complex tasks. Inspired by this, we design and experimentally demonstrate an adaptive hardware architecture Memristive Self-organizing Spiking Recurrent Neural
Network (MEMSORN). MEMSORN incorporates resistive memory (RRAM) in its synapses and neurons which configure their
state based on Hebbian and Homeostatic plasticity respectively. For the first time, we derive these plasticity rules directly
from the statistical measurements of our fabricated RRAM-based neurons and synapses. These “technologically plausible”
learning rules exploit the intrinsic variability of the devices and improve the accuracy of the network on a sequence learning
task by 30%. Finally, we compare the performance of MEMSORN to a fully-randomly set-up recurrent network on the same
task, showing that self-organization improves the accuracy by more than 15%. This work demonstrates the importance of the
device-circuit-algorithm co-design approach for implementing brain-inspired computing hardware.
The Course and Anatomical Characteristics of Sciatic and Femoral Nerves in Unilateral Crowe Type IV Hip Dysplasia
Authors: Song Ping , Kong Xiangpeng , Yang Minzhi , Chai Wei 
Published: October 2021

Abstract
Background
This study aims to investigate the course and anatomical characteristics of sciatic and femoral nerves in unilateral Crowe type IV developmental dysplasia of the hip (DDH) patients.
Methods
We conducted a retrospective own-control study of patients with unilateral Crowe type IV DDH. Bilateral hips’ CTs of 21 female patients were reviewed in our institute from February 2018 to February 2020. The distances between nerves and bony landmarks were measured in different CT sections (anterior superior iliac spine, acetabular inner wall, teardrop, and ischial tuberosity) to analyze the anatomical position and course of sciatic and femoral nerves between bilateral hips.
Results
In the section of acetabular inner wall, the distance between femoral nerve and acetabular anterior wall in affected hip (13.20±3.59 mm) was significantly smaller than that in healthy hip (16.58±5.12mm) (p=0.000). In other sections, the distances between nerves and bony landmarks in affected hips were significantly larger than or equal to those in healthy hips.
Conclusion
In female patients with unilateral Crowe type IV DDH, the femoral nerve in affected hip runs closer to anterior acetabular wall than that in healthy hip.
Integration of Oncology and Palliation Benefits Patients with Advanced Cancer and Unmet Needs: A Prospective Observational Study
Authors: Bye Asta , Bjerkeset Ellen , Stensheim Hanne , Loge Jon Håvard , Hjermstad Marianne Jensen , Klepstad Pål , Habberstad Ragnhild , Kaasa Stein , Aass Nina 
Published: October 2021

Abstract
Background: Patients with advanced cancer and bone metastases may have unmet palliative care needs that go unnoticed during clinical oncological practice. This observational study describes palliative care needs and interventions identified because of participation in a clinical study. Methods: Patients with advanced cancer and painful bone metastases included in the Palliative Radiotherapy and Inflammation Study (PRAIS) aiming to predict the response of radiotherapy (RT) were eligible. All patients met with the palliative care (PC) study team prior to start of RT, after they had completed patient reported outcome measures (PROMs). Symptoms prompting interventions by the study team were documented in the patient charts and reviewed.Results: One hundred-and thirty-three patients were reviewed; 63% males, mean age 65 and mean Karnofsky score (KPS) 73. Interventions were initiated in 50% (n=67) of the patients. Most common were changed opioid management (69%), treatment of constipation (43%) and nausea (24%) and nutritional advices (21%). Patients receiving interventions had lower mean KPS (70 vs 77 p <0.001), shorter survival time after study inclusion (median 28 vs. 57.5 weeks p = 0.005) and were more often opioid naïve (12% vs 39% p <.001) compared with the non-intervention group. Conclusions: Adverse symptoms are often not identified in routine oncological consultations prior to RT for cancer pain. Special attention should be directed to frail patients. These findings call for an early and systematic integration of palliative care in patients with advanced cancer.Trial registration: ClinicalTrials.gov NCT02107664