bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Conversational Assistant for Democratization of Data Visualization: A Comparative Study of Two Approaches of Interaction
Authors: Bhattacharya Abari , Di Eugenio Barbara , Grosso Veronica , Johnson Andrew , Tabalba Roderick , Kirshenbaum Nurit , Leigh Jason , Zellner Moira 
Published: December 2024

ABSTRACTData visualization is an important aspect of exploratory data analysis which requires expertise, posing a challenge to many users. In this work, we present a conversational system designed to make data visualization accessible, where users can generate visualizations of data by natural language conversational interaction with the system. We conducted a between‐subject study to compare two versions of our system, where users were asked to perform data exploration tasks. We did not find significant differences as concerns user assessments of their interactions with the system; however, we uncovered that users explore different properties of the data and reach different conclusions when using the two systems. We will discuss the general implications of our findings as regards the usage of conversational interfaces for visualization.
Response-Adaptive Randomization Designs Based on Optimal Allocation Proportions
Authors: Pin Lukas , Villar Sofia S. , Rosenberger William F. 
Published: December 2024

AbstractThis book chapter discusses response-adaptive randomization procedures which are based on optimal allocation proportions, e.g. derived from theoretical optimization problems. We elucidate the objectives of these proportions, emphasizing their role in maximizing statistical power and/or enhancing patient benefit. Moreover, practical insights on estimation and targeting of these allocation proportions are provided. A clinical trial example, the CALISTO trial, illustrates the application of these procedures. We aim to provide an overview that serves as a basis for discussions about optimal allocation proportions, assists in their implementation in practice and highlights future research areas.
Representation of Mooi Indie in Nature-Based Tourism: Development of Tourism in Bandung from 1925 to 1941
Authors: Lestari Esti Indah Puji , Mudaryanti Tri Wahyuning , Muas R. Tuty Nur Mutia Enoch 
Published: December 2024

AbstractThis chapter investigates the role of the social organization Bandoeng Vooruit in developing urban tourism, especially modern urban tourism from 1925 to 1941 in Bandung. In addition, it provides an overview of the history of tourism in Bandung and develops a historical study of Indonesian tourism in general. The primary sources of this study are the monthly magazine Mooi Bandoeng, published by Bandoeng Vooruit, and travel guidebooks (wandelgids). The results show that Bandoeng Vooruit played an important role in developing the pattern of modern urban tourism activities in Bandung. The chapter argues that Bandoeng Vooruit had a significant role in urban place-making in Bandung and shows that urban development in colonial Indonesia was not always a top-down state program.
Religion in Urban Politics: Social Media and Its Regulatory Debates in the Aftermath of the 2017 Jakarta Gubernatorial Election
Authors: Rumata Vience Mutiara , Karman  , Sastrosubroto Ashwin S. 
Published: December 2024

AbstractIn Indonesia, social media is a political tool for driving public opinion and social mobilization, and it can be used to facilitate public engagement. Recent political tension during the Jakarta gubernatorial election was driven by the polarization of ideologies on social media. This chapter discusses how and to what extent technology has sharpened this polarization by reviewing the literature and theoretical and conceptual framework pertaining to this topic. This chapter presents three discussions: (1) media and ideological polarization from historical and political perspectives; (2) social media as a value creator and amplifier in the polarization context; and (3) polarization in the Jakarta gubernatorial election and its potential impact on regulation. During the Jakarta gubernatorial election, social media enabled ideological polarization between Ahokers and pro-Rizieq Shihab on issues of tolerance/intolerance, radicalism, and Pancasila-Communism. This situation challenged current internet governance and regulation in Indonesia.
Prostitution and Its Social Impact in Gang Dolly, Surabaya (1967–1999)
Authors: Hayati Mala , Mudaryanti Tri Wahyuning 
Published: December 2024

AbstractThis chapter discusses the growth of prostitution in a local settlement in the Putat Jaya area, Surabaya, from 1967 to 1999. The main interconnections among morality, colonialism, prostitution, and contemporary urbanism are explored and established so that the Putat Jaya case might shed light on the problems of prostitution and morality in urban Indonesia today. After Indonesian independence, prostitution in Surabaya grew not only around the harbor area but also in places such as a cemetery. This red-light district, which came to be known as “Dolly,” attracted crowds and new businesses, thereby creating a strong relationship between the district’s operations and local people’s social and economic conditions. This study uses archives from the 1838 Staatsblad No. 30 Collection of the Library of the Indonesia National Archives. In addition, data are derived from the magazine Liberty (1991) and from first-hand interviews.
Enhancing physical and mechanical properties of single-layer particleboards bonded with canola protein adhesives: impact of production parameters
Authors: Tene Tayo Lawrence , Shivappa Nayaka Darshan , Cárdenas-Oscanoa Aldo Joao , Euring Markus 
Published: December 2024

Abstract
This study investigates the effects of various production parameters on the physical and mechanical properties of one-layer particleboards bonded with canola protein-based adhesives. Two protein-based adhesive formulations, CPI-B-0 with sodium bisulfate and CPI-N-60 with sodium nitrite crosslinkers, were examined under different conditions: binder content, press temperature, and press time factor. Results indicate that the CPI-N-60 outperformed the CPI-B-0 in terms of internal bonding strength (IB), modulus of rupture (MOR), and modulus of elasticity (MOE) due to the stronger covalent bonds formed with primary amines present in the protein adhesive. Increasing binder content led to significant improvements in mechanical properties, with the internal bonding and the MOR increasing by 21% and 9% when using 9% binder content over 7% respectively. The press temperature, as well as the press time were found to yield the highest influence on mechanical properties, with higher values resulting in better performance. Increasing the press temperature from 170 °C to 190 °C led to 33% increment in the internal bonding and 20% in the MOR, while 67% and 28% increment was obtained with 210 °C press temperature, respectively. Increasing the press time also led to an increase in the mechanical properties of the particleboards, by almost the same proportions as the effect of press temperature. The interaction effects between production parameters highlighted the importance of optimized conditions for achieving the desired properties. Indeed, under certain press conditions, the CPI-N-60 outperformed the conventional UF K345, achieving an IB value of 0.8 N/mm2 over 0.65 N/mm2. Overall, this study contributes to a better understanding of canola protein-based bio adhesive, with implications for the optimization of the production parameters for better boards’ properties.
Analytical solutions for particle dispersion in Taylor–Green vortex flows
Authors: Dagan Yuval 
Published: December 2024

Abstract
This study presents new analytical solutions for the dynamics and dispersion of particles laden in two-dimensional Taylor–Green vortex flows. Explicit solutions are found for the temporal evolution of free and forced particles under the viscous decaying vortical flow for low Stokes numbers. When placed in the vicinity of the vortex structure, forced particles may either trap within or escape the vortex cell, for which an explicit criterion is proposed. Using the same methodology, the trajectories of charged particles in a vortex flow in the presence of a magnetic field are solved. All cases are compared to numerical simulations demonstrating the validity of the proposed theoretical solutions. The explicit analytical solutions derived here provide fundamental insights into the complex phenomena of particle-vortex interactions and may be used to predict and control particle dispersion in various engineering and natural systems .
Evaluation of the cyto- and genotoxicity of two types of cellulose nanomaterials using human intestinal cells and in vitro digestion simulation
Authors: Vital Nádia , Cardoso Maria , Kranendonk Michel , Silva Maria João , Louro Henriqueta 
Published: December 2024

Abstract
Emerging cellulose nanomaterials (CNMs) may have commercial impacts in multiple sectors, being their application particularly explored in the food sector. Thus, their potential adverse effects in the gastrointestinal tract should be evaluated before marketing. This work aimed to assess the safety of two CNMs (CNF–TEMPO and CMF–ENZ) through the investigation of their cytotoxicity, genotoxicity (comet and micronucleus assays), and capacity to induce reactive oxygen species in human intestinal cells, and their mutagenic effect using the Hprt gene mutation assay. Each toxicity endpoint was analysed after cells exposure to a concentration-range of each CNM or to its digested product, obtained by the application of a standardized static in vitro digestion method. The results showed an absence of cytotoxic effects in intestinal cells, up to the highest concentration tested (200 µg/mL or 25 µg/mL, for non-digested and digested CNMs, respectively). Of note, the cytotoxicity of the digestion control limited the top concentration of digested samples (25 µg/mL) for subsequent assays. Application of a battery of in vitro assays showed that CNF–TEMPO and CMF–ENZ do not induce gene mutations or aneugenic/clastogenic effects. However, due to the observed DNA damage induction, a genotoxic potential cannot be excluded, even though in vitro digestion seems to attenuate the effect. The lowest digested CNF–TEMPO concentration induced chromosomal damage in Caco-2 cells, leading to an equivocal outcome. Ongoing research on epigenotoxic effects of these CNMs samples may strengthen the lines of evidence on their safety when ingested, paving the way for their innovative application in the food industry.
Harnessing magnetism: evaluation of safety, tolerance and feasibility of magnetic kidney stone retrieval in vivo in porcine models
Authors: Amiel Thomas , Srinivasan Shyam , Turrina Chiara , Ebel Florian , Straub Michael , Schwaminger Sebastian P. 
Published: December 2024

AbstractThe primary objective of urolithiasis therapy is complete stone removal and highest stone-clearance rates possible to minimize recurrence. A novel approach that employs a magnetic suspension and a magnetic probe for the passive collection and removal of small residual fragments was developed. This study assessed the feasibility of this system in porcine models. Five female domestic pigs underwent retrograde intrarenal surgery under general anaesthesia to assess the new magnetic system. Pre-analysed human calculi were endoscopically inserted and comminuted using lithotripsy. The magnetic suspension was applied, and the magnetic-stone fragment complex was extracted. After nephrectomy, independent blinded pathologists evaluated all the kidneys. Safety and tolerance assessments revealed no adverse events (i.e. no complications on the Clavien-Dindo scale > 1) or complications associated with treatment. This study revealed superficial urothelial damage in all animals, characterized by desquamation and inflammation, caused primarily by the insertion of access sheaths and laser lithotripsy. Residual magnetic particles were observed in the renal pelvis but did not show signs of toxicity even though this study is limited to the acute treatment. No pathological indicators were observed in the hemogram and urinalysis. Overall, the treatment did not cause any significant pathological changes. Preclinical in vivo evaluation of magnetic extraction of small rest fragments in porcine kidneys presents a promising, atraumatic approach for fragments removal. It demonstrated safety, tolerance, and feasibility that warrants clinical investigation. This method has the potential to increase stone-clearance rates with shorter extraction times, offering a possibility for addressing the challenge of urolithiasis in clinical practice.
Impact of absolute values and changes in meteorological and air quality conditions on community-acquired pneumonia in Germany
Authors: Khan Saeed A. , Brenner Thomas , Link Ann-Christine , Reudenbach Christoph , Bendix Jörg , Weckler Barbara C. , Kutzinski Max , Rupp Jan , Witzenrath Martin , Rohde Gernot , Pletz Mathias W. , Bertrams Wilhelm , Schmeck Bernd 
Published: December 2024

Abstract
Community-acquired pneumonia (CAP) is a major global health concern as it is a leading cause of morbidity, mortality and economic burden to the health care systems. In Germany, more than 15,000 people die every year from CAP. Climate change is altering weather patterns, and it may influence the probability and severity of CAP. The increasing frequency and intensity of extreme weather events necessitate the study of their impact on CAP hospitalizations. In this regard, we examine the influence of absolute values and changes in various meteorological and air quality conditions on the frequency of CAP hospitalizations. We matched weather data to the German CAPNETZ-Cohort of 10,660 CAP patients from 22 healthcare facilities between 2003 and 2017. Our findings show that daily fluctuations in meteorological conditions (maximum temperature, 99th percentile precipitation), apart from relative humidity, are likely to result in triggering CAP hospitalizations than absolute conditions. In contrast, the absolute values of air quality (CO, NO2, O3, PM2.5, SO2, and total aerosols) are found to exert a greater influence on CAP hospitalizations than changes in air quality. The study outcomes have implications for public health measures, early warning systems, and public awareness, with the aim of mitigating the risk of CAP.
3D waveforms and patterning behavior in thin monodisperse and multidisperse vertically-vibrated layers
Authors: Watson Peter , Bonnieu Sebastien Vincent , Anwar Ali , Lappa Marcello 
Published: December 2024

Abstract
Vibrofluidization in monodisperse granular materials is a hierarchical phenomenon involving different spatial and temporal behaviors, known to produce macroscopic structures with well-defined properties and high reproducibility. However, as witnessed by the paucity of relevant results in the literature, investigating the collective organization of particles across such different length and time scales becomes particularly challenging when multi-component systems are considered, i.e. if the considered vibrated material is not monodisperse. In this work, this problem is addressed through numerical simulation of the governing equations accounting for (dissipative) inelastic and frictional effects in the framework of a DEM (Discrete Element Method) method. Binary and ternary particle distributions are considered and, in order to filter out possible density-driven particle segregation or mixing mechanisms, particles are assumed to be iso-dense. The problem is initially analyzed through the coarse-grained lens of patterning behavior (supported by a Voronoi analysis for many representative cases) and then from a micromechanical level in which statistical data based on particle collisions and related dissipative effects are used to gain additional insights into the observed macroscopic trends. It is found that, starting from the initial traditional monodisperse case, the addition of particles with smaller sizes (while keeping the overall mass and depth of the considered layer almost unchanged) generally leads to a corrugation in the otherwise perfect symmetry of the original patterns, which is similar to that already seen in companion situations related to viscoelastic fluids. Moreover, while in the case of an initially hexagonal pattern, this topology is generally retained, in other situations, the initial perfection is taken over by less regular waveforms. Specific circumstances also exist where the initial square symmetry is lost in favor of a triangular symmetry. In all cases, segregation effects simply manifest as a preferential concentration of particles with larger size in an intermediate layer, which apparently behaves as a cohesive entity during each vibration cycle.
Mori-zwanzig approach for belief abstraction with application to belief space planning
Authors: Hou Mengxue , Lin Tony X. , Zhou Enlu , Zhang Fumin 
Published: December 2024

AbstractWe propose a learning-based method to extract symbolic representations of the belief state and its dynamics in order to solve planning problems in a continuous-state partially observable Markov decision processes (POMDP) problem. While existing approaches typically parameterize the continuous-state POMDP into a finite-dimensional Markovian model, they are unable to preserve fidelity of the abstracted model. To improve accuracy of the abstracted representation, we introduce a memory-dependent abstraction approach to mitigate the modeling error. The first major contribution of this paper is we propose a Neural Network based method to learn the non-Markovian transition model based on the Mori-Zwanzig (M-Z) formalism. Different from existing work in applying M-Z formalism to autonomous time-invariant systems, our approach is the first work generalizing the M-Z formalism to robotics, by addressing the non-Markovian modeling of the belief dynamics that is dependent on historical observations and actions. The second major contribution is we theoretically show that modeling the non-Markovian memory effect in the abstracted belief dynamics improves the modeling accuracy, which is the key benefit of the proposed algorithm. Simulation experiment of a belief space planning problem is provided to validate the performance of the proposed belief abstraction algorithms.
Molecular Signaling Pathways of Quercetin in Alzheimer’s Disease: A Promising Arena
Authors: Alsaleem Mansour A. , Al-kuraishy Hayder M. , Al-Gareeb Ali I. , Albuhadily Ali K. , Alrouji Mohammed , Yassen Asmaa S. A. , Alexiou Athanasios , Papadakis Marios , Batiha Gaber El-Saber 
Published: December 2024

AbstractAlzheimer’s disease (AD) is a neurodegenerative disease characterized by cognitive impairment and memory deficit. Even with extensive research and studies, presently, there is no effective treatment for the management of AD. Besides, most of drugs used in the treatment of AD did not avert the AD neuropathology, and the disease still in a progressive status. For example, acetyl cholinesterase inhibitors are associated with many adverse effects, such as insomnia and nightmares. As well, acetylcholinesterase inhibitors augment cholinergic neurotransmission leading to the development of adverse effects related to high acetylcholine level, such as salivation, rhinorrhea, vomiting, loss of appetite, and seizure. Furthermore, tacrine has poor bioavailability and causes hepatotoxicity. These commonly used drugs do not manage the original causes of AD. For those reasons, natural products were repurposed for the treatment of AD and neurodegenerative diseases. It has been shown that phytochemicals produce neuroprotective effects against the development and progression of neurodegenerative diseases by different mechanisms, including antioxidant and anti-inflammatory effects. Quercetin (QCN) has been reported to exert an effective neuroprotective effect against AD and other neurodegenerative diseases by lessening oxidative stress. In this review, electronic databases such as PubMed, Scopus, and Web of Science were searched for possible relevant studies and article linking the effect of QCN on AD. Findings from this review highlighted that many studies highlighted different mechanistic signaling pathways regarding the neuroprotective effect of QCN in AD. Nevertheless, the precise molecular mechanism of QCN in AD was not completely clarified. Consequently, this review aims to discuss the molecular mechanism of QCN in AD.
Transaction Costs, Participation, and the Cost-Effectiveness of Reverse Auctions: Evidence from a Laboratory Experiment
Authors: Li Tongzhe , Palm-Forster Leah H. , Bhuiyanmishu Siddika 
Published: December 2024

Abstract
Reverse auctions are often recognized as a tool that can cost-effectively allocate agri-environmental program funds to support environmentally-beneficial land management practices. However, transaction costs can limit participation in auctions which limits their cost-effectiveness. We use a laboratory experiment to examine how various levels of transaction costs influence participation and bidding behavior in discriminatory-price reverse auctions in low and high budget scenarios. Our experimental results show that transaction costs limit auction participation, increase bid amounts, and reduce cost-effectiveness. The negative effect of transaction costs on participation is particularly large when the budget level is low. Using the results of our experiment, we design a simulation to investigate whether reducing transaction costs via subsidies could increase program cost-effectiveness under various conditions. We find that transaction cost subsidies increase auction cost-effectiveness; however, our study raises new questions about how these subsidies are designed and the implications for the overall costs and benefits of efforts to reduce transaction costs in reverse auctions.
Diversity of HBCUs’ Institutional Human Capital: A Cross-Discipline, Longitudinal Analysis of Faculty Hiring and Placement at HBCUs
Authors: Yan Erjia , Palmer Robert T. , He Jiangen , Ni Chaoqun , Kelly Mat 
Published: December 2024

AbstractThis study examines the diversity of institutional human capital at Historically Black Colleges and Universities (HBCUs) by analyzing faculty educational backgrounds using a large data set on faculty hiring and placement. The analysis includes approximately four thousand faculty members employed at 10 research-intensive R2 HBCUs between 2011 and 2020. The results reveal that the 10 R2 HBCUs primarily hired tenure-track faculty from predominantly White R1 institutions. In contrast, HBCUs hired approximately 20% of their own graduates, while less than 10% of hires came from other HBCUs. Regarding placement, about 60% of HBCU graduates sought employment at HBCUs, while only a small number found employment at R1 institutions. Notably, Howard University placed 30 graduates at R1 institutions. This downward placement pattern underscores a significant trend: most HBCU hires are from R1 institutions, while HBCU graduates primarily find employment at institutions with lower research intensity. Understanding these patterns is crucial for addressing disparities in faculty representation and supporting the growth of Black professionals in academia.