bluuebunny/crossref_metadata_2025_split huggingface dataset:
Is Maximum Intensity Projection an Optimal Approach for Internal Target Volume Delineation in Lung Cancer?
Authors: Tibdewal Anil , Bushra Sabheen , Mummudi Naveen , Kinhikar Rajesh , Ghadi Yogesh , Agrawal Jai Prakash 
Published: August 2021

Purpose:
Respiratory-induced tumor motion is a major challenge in lung cancer (LC) radiotherapy. Four-dimensional computed tomography (4D-CT) using a maximum intensity projection (MIP) dataset is a commonly used and time-efficient method to generate internal target volume (ITV). This study compared ITV delineation using MIP or tumor delineation on all phases of the respiratory cycle.

Materials and Methods:
Thirty consecutive patients of LC who underwent 4D-CT from January 2014 to March 2017 were included. ITV delineation was done using MIP (ITVMIP) and all ten phases of the respiratory cycle (ITV10Phases). Both volumes were analyzed using matching index (MI). It is the ratio of the intersection of two volumes to the union of two volumes. A paired sample t-test was used for statistical analysis, and P < 0.05 was considered statistically significant.

Results:
The mean ± standard deviation volume of ITV10Phases was significantly larger compared to ITVMIP (134 cc ± 39.1 vs. 113 cc ± 124.2, P = 0.000). The mean MI was 0.75 (range 0.57–0.88). The mean volume of ITV10Phases not covered by ITVMIP was 26.33 cc (23.5%) and vice versa was 5.51 cc (6.1%). The mean MI was 0.73 for tumors close to the mediastinum, chest wall, and diaphragm. MI was not different between tumors ≤5 cm and >5 cm. The average time required for delineation was 9 and 96 min, respectively. The center of mass of two ITVs differed by 0.01 cm.

Conclusion:
ITV using MIP is significantly smaller and may miss a tumor compared to ITV delineation in 10 phases of 4D-CT. However, the time required is significantly less with MIP. Caution should be exercised in tumors proximity to the mediastinum, chest wall, and diaphragm.
Customization of a Model For Knowledge-Based Planning to Achieve Ideal Dose Distributions in Volume Modulated arc Therapy for Pancreatic Cancers
Authors: Nitta Yuya , Ueda Yoshihiro , Isono Masaru , Ohira Shingo , Masaoka Akira , Karino Tsukasa , Inui Shoki , Miyazaki Masayoshi , Teshima Teruki 
Published: August 2021

Purpose:
To evaluate customizing a knowledge-based planning (KBP) model using dosimetric analysis for volumetric modulated arc therapy for pancreatic cancer.

Materials and Methods:
The first model (M1) using 56 plans and the second model (M2) using 31 plans were created in the first 7 months of the study. The ratios of volume of both kidneys overlapping the expanded planning target volume to the total volume of both kidneys (Voverlap/Vwhole) were calculated in all cases to customize M1. Regression lines were derived from Voverlap/Vwhole and mean dose to both kidneys. The third model (M3) was created using 30 plans which data put them below the regression line. For validation, KBP was performed with the three models on 21 patients.

Results:
V18 of the left kidney for M1 plans was 7.3% greater than for clinical plans. Dmean of the left kidney for M2 plans was 2.2% greater than for clinical plans. There was no significant difference between all kidney doses in M3 and clinical plans. Dmean of the left kidney for M2 plans was 2.2% greater than for clinical plans. Dmean to both kidneys did not differ significantly between the three models in validation plans with Voverlap/Vwhole lower than average. In plans with larger than average volumes, the Dmean of validation plans created by M3 was significantly lower for both kidneys by 1.7 and 0.9 Gy than with M1 and M2, respectively.

Conclusions:
Selecting plans to register in a model by analyzing dosimetry and geometry is an effective means of improving the KBP model.
Heritabilitas Produki Telur Ayam Lokal Papua Berbeda Genotip dari Lokus 24- bp Insertion-Deletion dalam Promotor Gen Prolaktin
Authors: Mu'in Muhammad Affan , Lumatauw Sintje 
Published: August 2021

The heritability (h2) of a trait shows phenotypes variance of the trait caused by additive genetic variance. The h2 value is used to estimate the quantitative trait breeding value of livestock in order to improve these traits through selection. This study aims to estimate the h2 of egg production characteristics in Papua local chickens with different genotypes from the 24-bp InDel (Insertion-Deletion) locus in the prolactin gene promoter region (24-bp InDel/cPRLp locus). A total of 13 pairs of Papua local chickens consisting of 3 pairs of II genotypes (♂II x ♀II) and 11 female offspring, 5 pairs of ID genotypes (♂ID x ♂ID) and 19 female offspring, and 5 pairs of DD genotypes (DD x ♀DD) and 17 female offspring were used in this study. Observations were made on the characteristics of egg production in female offspring of each genotype group. The variance component for h2 estimation is obtained by the one-way analysis of variance method and the separation of the variance components for single pairs. The results showed that the h2 at first laying of eggs in all genotype groups was moderate (0.10 to 0.30); the h2 of the number of eggs produced from the time they first laid eggs until the age of 240 days in II and ID genotype groups was high (> 0.3), while in the DD genotype group was classified as moderate (0.10 to 0.30); and the h2 of egg weight in all genotype groups was moderate (0.10 to 0.30). The high h2 of a trait indicates that the trait is more dominated by additive genes and is more responsive to the selection treatment.
Data Security Analysis Against Chosen Ciphertext Secure Public Key Attack Using Threshold Encryption Scheme
Authors: Khairunas  , Zarlis Muhammad , Sawaluddin  
Published: August 2021

A public key encryption cryptography system can be utilized to generate ciphertext of a message using a public key. However, this public key encryption cryptography system cannot be utilized if you want to generate ciphertext using several different keys. Solving the problems above can use the Chosen Ciphertext Secure Public Key Threshold Encryption scheme but are the securities from Threshold Encryption really strong in securing messages, therefore the above problems can be analyzed for Data Security Against Chosen Ciphertext Secure Public Key Attacks Using Threshold Encryption Schemes. The work process starts from Setup which functions to generate the server's private key and public key. Then, the process is continued with ShareKeyGen which functions to generate private keys based on the user's identity. After that, the process continues with ShareVerify which serves to verify the key generated from the ShareKeyGen process. The process will be continued again with Combine which serves to generate a private key that will be used in the decryption process. After that, the process will continue with the encryption process of the secret message. The ciphertext obtained will be sent to the recipient. The receiver verifies the ciphertext by running ValidateCT. Finally, the ciphertext is decrypted by running Decrypt. The software created can be used to display the workflow process of the Threshold schema. In addition, it makes it easier to test intercepts of ciphertext messages to other users so that generic securities analysis is carried out in testing the resulting ciphertext. The results of the implementation of Threshold Encryption algorithm scheme can protect important personal data, because it involves human rights, namely the right to access, the right to delete, the right to correct, the right to be corrected and the right to transfer personal data safely from attacks.
Erudition after neonatal gastric transposition for esophageal atresia at 10 years of follow-up
Authors: Sharma Kanika , Sharma Shilpa , Gupta Devendra Kumar 
Published: August 2021

Background: Gastric transposition (GT) is a well-established procedure of esophageal re­placement (ER) for children with esophageal atresia. ER in the neonatal period is sparsely reported. We report characteristics of children who have undergone neonatal GT and have completed ten years of follow-up.
Methods: The cross-sectional study was conducted which included all children who under­went neonatal GT at the institute and have completed a follow-up of at least 10-years. An­thropometry, oral contrast study, Hepatobiliary Scintigraphy, Gastroesophageal reflux study, Gastric emptying test, spirometry, and blood investigations were done for all the children.
Results: Four children (three male and one female) were included in the study. The mean age at ER was 5.3 ±2.2 days with a mean birth-weight of 2.43 ±0.13 kg. Two children had prima­ry GT, while the other two had GT following a leak in primary anastomosis. During the mean follow-up of 180.25 ±43.5 months, none of the children required esophageal dilatation or other surgical intervention or procedures. All children were below 3rd centile for weight-for-age while all except one were below 50th centile for height-for-age. There was no stricture on oral contrast study, however, one child had grade III reflux on GER scan. Persistent duode­nogastric reflux on HIDA scan was seen in one child. Three children had restrictive parame­ters on spirometry. Symptomatically, all reported poor weight gain, one had left vocal cord palsy with hoarseness, and one had chest-wall protuberance.
Conclusions: Neonatal gastric transposition is a feasible alternative to delayed esophageal replacement for neonates with esophageal atresia with limited complications.
Some aspects of winter wheat productivity
Authors: Kuzenko M. V. 
Published: August 2021

The article presents studies carried out in 2018–2019 and 2019–2020 in the southern foothill zone of the North-West Caucasus in the fields of the selection and primary seed produc- tion department of the Adygh Research Institute of Agriculture. The aim was to study the actual, biological or potential yield of winter soft wheat varieties cultivated in the region, as well as the ratio of the mass of the grain part and the harvested straw - the yield index. The studied varieties were divided into groups according to plant height: semi-dwarfs (up to 90 cm), short-stemmed (up to 105 cm), medium-sized (up to 120 cm). According to the results of the studies carried out, differences in the studied characteristics were revealed. In the group of semi-dwarf varieties, the grain yield varied from 7,25 to 8,05 t/ha, short-stemmed 7,78–8,91 t/ha, medium-sized 7,34–9,60 t/ha. The highest grain yield was shown by the Vekha variety (9,60 t/ha) belonging to the group of medium-sized varieties, from the short-stemmed Maikopchanka varieties (8,91 t/ha) stood out, Kalym semi-dwarf varieties (8,05 t/ha). The biological yield in the experiment varied from 9,37 to 15,29 t/ha. From semi-dwarf varieties, Grom stood out (14,06 t/ha), short-stemmed varieties – Mafe (10,8 t/ha), medium-sized varieties – Vekha (15,29 t/ha). The difference between the actual and biological grain yield of varieties belonging to the short-stem group was the smallest in comparison with the varieties of the semi-dwarf and medium-grown group. On average, over two years of research, the harvesting index was 46,9–53,2%. Semi-dwarf winter wheat varieties had the maximum value of this indicator. In the group of short-stemmed Grom and Graf varieties, the ratio of the mass of the grain part to the harvested straw varied from 46,8% (Velena) to 50,5% (Alekseich). The harvesting index for medium-sized varieties was at the level of 46,9–51,8%. The Vekha variety, which showed the maximum value, stood out from this group.
Simulation of synbiotic ice cream fermentation process
Authors: Vavilova M. A. 
Published: August 2021

Expanding the range of products of therapeutic and prophylactic orientation is a priority direction of the state policy in the field of healthy nutrition. Products enriched with functional components improve the general state of the body, have high organoleptic characteristics in combination with increased biological value. The production of synbiotic ice cream is one of the promising trends in the dairy industry. Due to its unique composition and technological peculiarities, the ice cream retains the desired organoleptic and functional properties. Pro- and prebiotic components in it are conserved by freezing, and activated only when they enter the organism. It has been established experimentally, that high concentrations of monosaccharides have an inhibitory effect on the development of probiotic cultures, therefore, the purpose of the research is to simulate the fermentation process of the ice cream enriched with prebiotic components, in order to determine optimal characteristics and establish rational syrup concentrations. Lactic bacteria of Lactobacillus acidophilus species that remain active in a wide temperature range and suppressing pathogenic microflora, as well as berry syrup with a high concentration of vitamins and minerals have been used as components that ensure the functionality of the product. Phased addition of syrup has been recommended for the ex- periment. As a result of the research, a model recipe for synbiotic ice cream has been developed, the quantitative regularities of the influence of various concentrations of fructose syrup on the process of fermentation of compound have been determined, organoleptic characteristics of soft-serve ice cream have been investigated, a power-law model of the dependence of the duration of fermentation on the mass fraction of fructose syrup has been obtained. It has been found that a decrease in the initial concentration makes it possible to shorten the technological cycle and regulate the acidity index.
Prevalence of HIV among pregnant women in three HIV-affected districts in Sindh, Pakistan
Authors: Ajmal Agha  , Fozia Ajmal  , Afshan Khurshid  , Altaf Ahmed Soomro  , Nazia Farrukh  , Nikhat Iftikhar  
Published: August 2021

Objective: To conduct a community-based cross-sectional survey to determine the prevalence of human immunodeficiency virus (HIV) among pregnant women in taluka Ratodero, Larkana, and two adjacent talukas: Sajawal, district Kambar Shahdadkot and Garhi Yasin, district Shikarpur.
Methods: The study was conducted among pregnant women in the three talukas of rural Sindh: Ratodero, Garhi Yasin, and Sajawal, from October 16, 2020 - December 23, 2020. A total of 1,157 pregnant women were interviewed at their homes and tested using the AlereTM HIV Combo rapid finger prick test. The study captured women's sociodemographic, economic, and health characteristics, including age, education, employment, number of children, home or hospital delivery, antenatal care use, antenatal trimester, history of blood transfusion, and HIV test result. Descriptive statistics were calculated: percentages for categorical variables and mean ± standard deviation (SD) for continuous variables.
Results: It was found that 0.35% (4/1,157) of women were HIV-positive, of which 3 were in Ratodero, Larkana, and 1 was in Garhi Yasin, Shikarpur. The average age of women was 28.7 ± 4.0 years. Most of the women (n=1067; 92.2%) of women did not attend a school, and 99.0% (n=1145) had never had a formal job. The average gestational age was 7.6 (±2.2) months. More than three-quarters of the women participating in the study (n=894; 77.3%) were not registered with a formal healthcare facility for antenatal care.
Continuous...
PENGARUH PENGGUNAAN AIR KOLAM TERHADAP KUAT TEKAN BETON (Studi Kasus Kecamatan. Kateman, Keritang dan Tembilahan Kota)
Authors: Juldin Muhammad , Alfa Akbar 
Published: August 2021

AbstractConcrete is a composite material (mixture) consisting of cement, coarse aggregates, fine aggregates and water. The concrete formation mixture is designed in such a way as to produce fresh concrete that is easy to work with and meets the plan's compressive strength after hardening.The cement used is PCC type cement, although the composition of cement in concrete is only about 10%, but the role of cement is very important in concrete. Aggregates are mineral granules originating from nature or artificial which have a function as a mixture of fillers in concrete. The aggregate of the concrete mixture filler is divided into fine aggregates used from Javanese Inhu and coarse aggregates from Tanjung Balai Karimun. The fine aggregate is usually in the form of sand that passes through a filter with a diameter of 4.75 mm or 5 mm, while coarse aggregates do not pass through the filter. The water used is well water from Kateman District, Keritang District and Tembilahan District, Indragiri Hilir Regency, Riau Province.The compressive strength of concrete is the amount of load per unit area which causes the concrete specimen to break and there is no more carrying capacity. The average compressive strength of 28 days of cube specimens with well water in Kateman District = 491 kg / cm2, Keritang District = 469 kg / cm2 and Tembilahan District City = 475 kg / cm2.

AbstrakBeton merupakan bahan komposit (campuran) yang terdiri dari semen, agregat kasar, agregat halus dan air. Campuran bahan-bahan pembentukan beton dirancang sedemikian rupa, sehingga menghasilkan beton segar yang mudah dikerjakan dan memenuhi kekuatan tekan rencana setelah mengeras.Semen yang digunakan adalah semen tipe PCC, walaupun komposisi semen dalam beton hanya sekitar 10%, namun peran semen sangat penting dalam beton. Agregat adalah butiran mineral yang berasal dari alam atau buatan yang memiliki fungsi sebagai bahan pengisi campuran pada beton. Agregat pengisi campuran beton terbagi atas agregat halus yang digunakan berasal dari Japura Inhu dan agregat kasar berasal dari Tanjung Balai Karimun. Agregat halus biasanya berupa pasir yang lolos saringan dengan diameter 4,75 mm atau 5 mm, sedangkan agregat kasar tidak lolos saringan tersebut. Air yang digunakan yakni air sumur berasal dari Kecamatan Kateman, Kecamatan Keritang dan Kecamatan Tembilahan Kota Kabupaten Indragiri Hilir Provinsi Riau.Kuat tekan beton adalah besarnya beban per satuan luas yang menyebabkan benda uji beton pecah dan tidak ada lagi daya dukungnya. Hasil kuat tekan rata-rata umur 28 hari benda uji kubus dengan air sumur Kecamatan Kateman = 491 kg/ cm2, Kecamatan Keritang = 469 kg/cm2dan Kecamatan Tembilahan Kota = 475 kg/cm2.
ANALISA KEBUTUHAN AIR BERSIH (STUDI KASUS DESA SIMPANG GAUNG KECAMATAN GAUNG KABUPATEN INDRAGIRI HILIR)
Authors: Saputra Wiro 
Published: August 2021

Abstract
Water is a basic need for human survival, clean water needs continue to increase while the supply of raw water infrastructure is still limited, there is often a lack of fulfillment of needs during the dry season, clean water crisis is one of the problems in Indragiri Hilir District especially in Simpang Gaung Village.
Planning for a clean water distribution system really needs to be taken into account in order to guarantee the fulfillment of the level of service, in planning the clean water pipeline is determined by the water requirements and the required flow pressure. The amount or discharge of water provided depends on the population and industry served. The purpose of this study is to obtain clean water needs and a piping network system 15 based on the needs of the population in the next 15 years.
The population of Simpang Gaung Village in 2018 is 4,100 people, with the semi average soul method of population growth up to 2033 is 4,283 people. The total water demand with a population of 4334 million in 2033 is 2.9420 liters / second. The source of water used is the river.

Abstrak
Air merupakan kebutuhan yang mendasar bagi kelangsungan hidup manusia, kebutuhan air bersih terus meningkat sementara penyediaan prasarana air baku masih terbatas, sering terjadi kekurangan pemenuhan kebutuhan saat musim kemarau, krisis air bersih merupakan salah satu masalah di Kabupaten Indragiri Hilir khusunya di Desa Simpang Gaung.
Perencanaan sistem distribusi air bersih sangat perlu diperhitungkan agar dapat menjamin terpenuhinya tingkat pelayanan, pada perencanaan jaringan pipa air bersih ditentukan oleh kebutuhan air dan tekanan aliran yang diperlukan. Jumlah atau debit air yang disediakan tergantung pada jumlah penduduk dan industri yang dilayani. Tujuan dari studi ini adalah untuk mendapatkan kebutuhan air bersih dan sistim jaringan perpipaan 15 berdasarkan kebutuhan penduduk 15 tahun kedepannya.
Jumlah penduduk Desa Simpang Gaung tahun 2018 berjumlah 4.100 jiwa, dengan metode semi average jiwa pertumbuhan penduduk sampai dengan tahun 2033 adalah 4.283 jiwa. Total kebutuhan air dengan jumlah penduduk 4334 juta jiwa pada tahun 2033 adalah 2,9420 liter/detik. Sumber air yang digunakan adalah sungai.
Nutrigenomics: Understanding the Role of Nutrients and Gene Interactions in Periodontal Disease
Authors: Aghanashini Suchetha , Bhat Divya , Nadiger Sapna , Nellipunath Aparna Suraj , Mallikarjunappa Apoorva Sokke , Mundinamane Darshan Basavarajappa 
Published: August 2021

ABSTRACTPeriodontal disease is a progressive inflammatory process, involving periodic destruction of periodontal attachment apparatus and loss of structures of the apparatus, essentially gingiva, periodontal ligament, cementum, and alveolar bone, ultimately resulting in loss of tooth in most susceptible patients.1Advanced knowledge on the pathogenesis of periodontal destruction and the role of nutrients on it, has increased the interest to determine the relationship between periodontal disease and nutrition.2It is also essential to know that periodontal disease risk is determined by genotype and dietary interactions.3Nutrients that play an important role in inflammatory and immune responses can in turn regulate and modulate periodontal health.4Nutrigenomics is a branch of nutritional genomics, which uses genomic tools in nutritional research to focus on the identification and understanding of the molecular-level interaction between nutrients and genomes.5It provides information on the influence of nutrition on the metabolic pathways and homeostatic control and also allows us to know the disturbances arising in this regulation, at an early stage.6This literature review provides a detailed description of the role of nutrition in periodontal disease and recommends the daily nutritional intake necessary for the prevention of periodontal disease.7How to cite this article:Nellipunath AS, Aghanashini S, Mallikarjunappa AS,et al.Nutrigenomics: Understanding the Role of Nutrients and Gene Interactions in Periodontal Disease. J Contemp Dent 2019;9(3):135–140.
TÌM HIỂU MỘT SỐ YẾU TỐ LIÊN QUAN ĐẾN KẾT QUẢ PHỤC HỒI CHỨC NĂNG NHẬN THỨC TRÊN BỆNH NHÂN CHẤN THƯƠNG SỌ NÃO
Authors: Văn Minh Phạm , Thị Kiều Loan Phan 
Published: August 2021

Suy giảm nhận thức do chấn thương sọ não có thể ảnh hưởng đến nhiều lĩnh vực bao gồm chú ý, ngôn ngữ, trí nhớ, nhận thức tri giác và chức năng điều hành. Mục tiêu: Tìm hiểu một số yếu tố liên quan đến kết quả phục hồi chức năng nhận thức trên người bệnh chấn thương sọ não. Đối tượng và phương pháp nghiên cứu: Phương pháp nghiên cứu tiến cứu, so sánh kết quả trước và sau can thiệp trên 33 bệnh nhân bệnh nhân chấn thương sọ não trên 18 tuổi vào điều trị nội trú tại bệnh viện Phục hồi chức năng Hà Nội. Kết quả và kết luận: Bệnh nhân chấn thương sọ não chủ yếu là nam giới chiếm tỷ lệ 78,8%, nữ giới chiếm 21,2%, tỷ lệ nam/nữ là 3.71/1. Độ tuổi và giới tính không ảnh hưởng đến phục hồi chức năng nhận thức của bệnh nhân chấn thương sọ não (p> 0,05). Những bệnh nhân có thời gian mắc bệnh dưới 6 tháng và trên 6 tháng không ảnh hưởng đến PHCN nhận thức của bệnh nhân chấn thương sọ não (p> 0,05).