bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Review Article on the Therapeutic Potential of Medicinal Plants for Prevention and Treatment of Secondary Infection in Patients with COVID-19
Authors: Patil Asmita Gajbhiye , Rathore Swati , Tiwari Richa Tripathy , Rai Neha , Mahapatra Debarshi Kar , Patil Shailendra 
Published: December 2021

:COVID-19 is an infectious disease, caused by SARS-CoV-2 (severe acute respiratory syndrome coronavirus-2) that is rapidly spreading all over the world and responsible for the international health crisis. In an earlier period, various synthetic antiviral drugs and clinical therapies have been used to control the viral infection but at present, there is no specific treatment available for COVID-19 infection. Several approaches like ritonavir, lopinavir, hydroxychloroquine, and chloroquine have been proposed. India is a hub of medicinal plants, so there is a chance to find out the way to combat the COVID-19 pandemic. The medicinal herbal formulations may enhance the immunity and come up with a powerful antiviral drug, which is an urgent need to control the outbreak of coronavirus. In this review article, we have discussed epidemiology, clinical outcomes, treatment, and prevention of this novel epidemic coronavirus from medicinal herbal formulations perspective. We have also emphasized the reported antiviral activity and immunity-boosting property of the Indian medicinal plants. This article also suggests that the drug or formulation obtained from medicinal plant sources may have low fatal outcomes, quick response, and safe in the management and prevention of this pandemic outbreak.
A Short Appraisal on Gold Nanoparticles: Recent Advances and Applications
Authors: Singh Dilpreet , Tonjam Russel , Chaudhary Tanu , Bhatia Tanuja , Razdan Karan , Kurmi Balak Das , Tiwari Prashant , Gupta Sakshi 
Published: December 2021

:
Owing to their unique characteristics and diverse surface activities, gold nanoparticles (AuNPs) have been widely used in various fields of biology. The ease with which AuNPs can be functionalized makes it a useful platform for nanobiological assemblies containing oligonucleotides, antibodies, and proteins. AuNPs bioconjugates have also emerged as an interesting candidate for the development of novel biomaterials for the study of biological systems. AuNPs' flexibility has made them valuable in a variety of biomedical applications. The binding of analytes to AuNPs can change the physicochemical features of AuNPs, such as surface plasmon resonance, conductivity, and redox activity, resulting in observable signals in diagnostics. AuNPs can also be used as a therapeutic platform because of their large surface area, which allows for a dense presentation of multifunctional moieties (e.g., drugs and targeting agents). We present a brief summary of green synthesis, characteristics, and applications of gold nanoparticles in this paper, as well as their translational potential.
Usability Testing of a Patient-Centered Mobile Health App for Supporting and Guiding the Pediatric Emergency Department Patient Journey: Mixed Methods Study
Authors: Rochat Jessica , Ehrler Frédéric , Siebert Johan N , Ricci Arnaud , Garretas Ruiz Victor , Lovis Christian 
Published: December 2021

Background
Patient experience in emergency departments (EDs) remains often suboptimal and can be a source of stress, particularly in pediatric settings. In an attempt to support patients and their families before, during, and after their visit to a pediatric ED, a mobile health (mHealth) app was developed by a multidisciplinary team based on patient-centered care principles.

Objective
This study aims to evaluate the usability (effectiveness, efficiency, and satisfaction) of a new mHealth app, InfoKids, by potential end users through usability testing.

Methods
The app was assessed through an in-laboratory, video-recorded evaluation in which participants had to execute 9 goal-oriented tasks, ranging from account creation to the reception of a diagnostic sheet at the end of the emergency care episode. Effectiveness was measured based on the task completion rate, efficiency on time on task, and user satisfaction according to answers to the System Usability Scale questionnaire. Think-aloud usability sessions were also transcribed and analyzed. Usability problems were rated for their severity and categorized according to ergonomic criteria.

Results
A total of 17 parents participated in the study. The overall completion rate was 97.4% (149/153). Overall, they reported good effectiveness, with the task successfully completed in 88.2% (135/153) of cases (95% CI 83%-93%). Each task, with the exception of the first, created difficulties for some participants but did not prevent their completion by most participants. Users reported an overall good to excellent perceived usability of the app. However, ergonomic evaluation identified 14 usability problems occurring 81 time. Among these, 50% (7/14) were serious as their severity was rated as either major or catastrophic and indicated areas of improvements for the app. Following the suggested usability improvements by participants, mitigation measures were listed to further improve the app and avoid barriers to its adoption.

Conclusions
Usability of the InfoKids app was evaluated as good to excellent by users. Areas of improvement were identified, and mitigation measures were proposed to inform its development toward a universal app for all ED patients visiting a digitalized institution. Its contribution could also be useful in paving the way for further research on mobile apps aimed at supporting and accompanying patients in their care episodes, as research in this area is scarce.
Designing an Adaptive Adolescent Physical Activity and Nutrition Intervention for COVID-19–Related Health Challenges: Formative Research Study
Authors: Grimes Amanda , Lightner Joseph S , Pina Kimberly , Donis de Miranda Evelyn S , Meissen-Sebelius Emily , Shook Robin P , Hurley Emily A 
Published: December 2021

Background
With rates of childhood obesity continually increasing, effective physical activity and nutrition interventions are needed. Formative research is used to tailor interventions to different cultural and geographic contexts and can be vital in adapting intervention strategies in the face of significant disruptive circumstances (like COVID-19).

Objective
We conducted formative research via in-person and web-based focus groups among middle schoolers and parents to better understand the facilitators and barriers to physical activity and fruit and vegetable consumption and to inform the design of a large intervention for a low-income, urban setting in the US Midwest.

Methods
We conducted 2 phases of qualitative focus groups with parents (n=20) and 6th-9th grade middle schoolers (n=23). Phase 1 was conducted prior to the COVID-19 pandemic in late 2019, and phase 2 was conducted during the COVID-19 pandemic in the summer of 2020. Focus groups were transcribed and thematically coded using the Dedoose software.

Results
The main facilitators of physical activity prior to the pandemic included the opportunity to have fun, peer influence, competition (for some), and incentives, while the main barriers to physical activity were time constraints and social discomfort. The main facilitators of eating fruits and vegetables included parental influence, preparation technique, and convenience, while barriers included dislike of vegetables, time constraints, and preparation or freshness. During the pandemic, facilitators of physical activity remained the same, while additional barriers to physical activity such as lack of motivation and limited time spent outside of the home were reported. For fruit and vegetable consumption, both facilitators and barriers remained the same for both time periods. Additionally, for some participants, the pandemic offered an opportunity to offer more fruits and vegetables to middle schoolers throughout the day.

Conclusions
Some themes identified were common to those reported in previous studies, such as peer influence on physical activity and parental influence on fruit and vegetable consumption. Novel themes such as lack of motivation to be active and limited time outside the home helped improve intervention adaptation, specifically during the COVID-19 pandemic. The continuity of formative research after a major unexpected change in the intervention context can be essential in targeting areas of an intervention that can be retained and those that need to be adjusted.
Pengaruh Perbedaan Asal Sekolah dan Motivasi Belajar Terhadap Pemahaman Konsep Dasar Akuntansi Mahasiswa Program Studi Pendidikan Akuntansi STKIP PGRI Sumatera Barat
Authors: Putri Sherly Ganda , Syamra Yesmira , Pratama Indra Mulia 
Published: December 2021

This study aims to analyze: 1.) To analyze differences in school origin affect the understanding of basic accounting concepts 2.) To analyze learning motivation affect the understanding of basic accounting concepts 3.) To analyze Differences in school origin and learning motivation have an effect on understanding the basic concepts of accounting. This type of research is associative and descriptive. The population of this study were students of the STKIP PGRI West Sumatra Accounting Education Study Program class 2017, 2018, and 2019 which amounted to 114 people. The sampling technique used is proportional random sampling with a total sample of 89 people. Data analysis using multiple linear regression analysis and hypothesis testing using f test and t test. Data analysis was assisted by SPSS version 15 and eviews version 8. The results showed that: 1.) Differences in school origin had no positive and significant effect on understanding the basic concepts of accounting. 2.) Learning motivation has a positive and significant effect on understanding the basic concepts of accounting. 3.) Differences in school origin and learning motivation have an effect on understanding the basic concepts of accounting.
Análisis de los modos de fallo del sistema de gestión de energía de un Cubesat
Authors: Aybar Mejía Miguel , Hidalgo de los Santos Lía , Del Rosario Peñaló Diorys , Sánchez Edwin , Mariano-Hernández Deyslen 
Published: December 2021

Un satélite es un dispositivo que se sitúa en órbita alrededor de la Tierra con fines científicos, militares, educacionales o de comunicaciones. Se pueden clasificar según su peso como: satélites grandes, que pesan más de 1,000 kilogramos (kg), satélites medianos, que pesan entre 500-1,000 kg, y satélites pequeños, que pesan menos de 500 kg. Dentro de los satélites pequeños se encuentran los nanosatélites, los cuales pesan entre 1-10 kg. La principal ventaja que poseen los nanosatélites es que son capaces de realizar misiones complejas a un menor costo. Dentro de las limitaciones que estos presentan es que tienen poca capacidad para captar y almacenar energía debido a su tamaño. Considerando la importancia del sistema de energía durante el funcionamiento de los satélites, este artículo analiza los modos de fallos que se presentan en el sistema y cómo estos afectan a los sistemas de generación y almacenamiento de energía. Para la simulación de estos sistemas se determinaron la cantidad mínima de paneles solares y baterías necesarios para su correcto funcionamiento. Los resultados obtenidos muestran que con este análisis se logra dimensionar correctamente el sistema de gestión de energía, reduciendo el tamaño de estos y a su vez el peso dentro del satélite.
Discurso de la Niñez Sujeto sobre la Migración Forzada
Authors: Villegas Margarita , Balaguera Erika , García Rozo Marina , González Fredy Enrique 
Published: December 2021

Se analiza el discurso de la niñez venezolana como sujetos de migración forzada, a fin de explorar el significado que para ellos tiene el proceso migratorio experimentado y hacer visible sus ideas y representaciones del mismo, pues frecuentemente están ausentes en las agendas públicas. Estudio exploratorio y cualitativo realizado con cuatro niños y dos niñas, durante tres encuentros, usando como técnicas lluvia de ideas y conversaciones, a cuyas textualizaciones se les aplicó análisis de contenido siguiendo los aportes de Glaeser y Strauss (1967). Los resultados destacan: expresiones de desarraigo relativas al nuevo territorio, dificultades de integración por el rechazo como migrantes, al tiempo que en sus discursos interpretan el contexto social que les envuelve. Se percibe, aun cuando reconocen aspectos positivos del país de acogida, la necesidad de ofrecer programas de acompañamiento que permita incorporar sus ideas, garantizándoles sus derechos, en los proyectos educativos que contemplen la diversidad multicultural de la niñez migrante.
Patskaņa  lietojums nomenu, verbu un adverbu gala zilbēs: dziļo tāmnieku izlokšņu piemērs
Authors:   Latvijas Universitātes Latviešu valodas institūts, Vēvere Daira 
Published: December 2021

Publikācijā aprakstīts lībiskā dialekta dziļajām tāmnieku izloksnēm raksturīgais patskaņa  un tā fonētisko variantu e,  un a lietojums nomenu, verbu un adverbu gala zilbēs Popes, Ziru, Piltenes, Zlēku, Ances, Dundagas un Ugāles izloksnē. Pētījuma pamatā ir pētāmo izlokšņu runas dati, kas iegūti laikā no 2008. līdz 2019. gadam. Salīdzināšanai, kā arī aprakstāmās lingvistiskās parādības izplatības un dinamikas noskaidrošanai izmantoti 20. gs. 50. un 60. gados iegūtie izlokšņu materiāli, kas glabājas Latvijas Universitātes Latviešu valodas institūta (LU LaVI) izlokšņu arhīvā. Pētījuma rezultāti rāda, ka patskanis  dziļajās tāmnieku izloksnēs visbiežāk sastopams vienskaitļa un daudzskaitļa lokatīvā, mazāk – vienskaitļa un daudzskaitļa datīvā. Vietas adverbi, kas beidzas ar patskani  vai tā fonētiskajiem variantiem  un e, mūsdienās konstatēti visās pētāmajās izloksnēs. Ancē un Dundagā patskanis  un e joprojām saklausāms noteikto adjektīvu un kārtas numerāļu gala zilbēs. Arī saīsinātās verbu formas, kas beidzas ar - resp. -e, mūsdienās saglabājušās galvenokārt Dundagas un Ances izloksnē, kaut 2008. un 2010. gadā tās vēl tika konstatētas Piltenes un Zlēku izloksnē. Pārveidotās verbu un substantīvu atgriezeniskās formas mūsdienās reģistrētas pārsvarā Ancē un Dundagā. Kopumā secināms, ka mūsdienās sarūk patskaņa  un tā variantu lietojums nomenu, verbu un adverbu gala zilbēs tajās pozīcijās, kur literārajā valodā tiek lietoti patskaņi ā, ē, ī, ū, a, u, i un divskaņi uo, ai, ie, tomēr tā vēl aizvien ir uzskatāma par tipisku dziļo tāmnieku izlokšņu parādību.
Possíveis fontes e processos magmáticos do Granito Chasqueiro, SE do Cinturão Dom Feliciano, Brasil
Authors: Vieira Daniel Triboli , Koester Edinei , Ramos Rodrigo Chaves , Lenz Cristine 
Published: December 2021

Este trabalho apresenta novas constatações sobre a evolução do Granito Chasqueiro, uma das principais ocorrências de rochas graníticas cálcico-alcalinas alto-K no Cinturão Dom Feliciano, no extremo sul do Brasil. O objetivo deste trabalho é discutir as principais fontes e processos magmáticos envolvidos na evolução deste granito durante o Ediacarano (574 Ma), com base em novos dados de geoquímica isotópica (Sr-Nd, rocha total) em amostras representativas do granito e dos enclaves dioríticos associados. O granito mostra razões 87Sr / 86Sr(t) intermediárias (0,7095–0,7139), εNd(t) negativo (-0,36 a -2,94) e TDM entre 1,25 e 1,33 Ga. A amostra de enclave máfico apresenta razões 87Sr / 86Sr(t) = 0,74672, mais elevadas que aquelas do granito, ƐNd negativo (-1,63) e TDM de 1,15 Ga. Com base nos dados de isótopos apresentados neste estudo, juntamente com dados geoquímicos de rocha total compilados de trabalhos anteriores, sugerimos que os principais processos de evolução magmática do Granito Chasqueiro são: (i) mistura de magmas, onde cada magmatismo (máfico e félsico) possui fontes e processos evolutivos diferentes; (ii) retrabalhamento crustal das rochas máficas e gnaisses do embasamento regional (εNd(t) negativo); (iii) processo de cristalização fracionada, marcado por concentrações e depleções expressivas em Ba, Sr, P, Nb, Ti, e Eu, que reforçam a extensa cristalização fracionada dos líquidos primários. Como resultado destes processos, o Granito Chasqueiro é altamente diferenciado, com composições semelhantes a granitos Tipo-I.
Caenorhabditis elegans como modelo de infección para el estudio de antimicrobianos
Authors: Rodríguez Morales Dayana , Lozano Jiménez Yenny Yolanda , Sánchez Mora Ruth Mélida 
Published: December 2021

A pesar de algunas limitaciones éticas, los animales juegan un papel importante como anfitriones sustitutos para investigar los mecanismos fisiopatológicos de enfermedades con el fin de indagar en ellos medicamentos contra diferentes patologías. Uno de los grandes problemas en salud pública a nivel mundial en el contexto farmacológico es la producción de antibióticos y la ocurrencia de resistencia microbiana, además, cada vez resulta más omplejo el uso de modelos animales por las restricciones bioéticas actuales, no obstante, es necesario usar modelos simples en los estudios preliminares que permitan evaluar las interacciones huésped-patógeno-antimicrobiano. Al validar que Caenorhabditis elegans es susceptible a varias bacterias y además tiene la capacidad de responder a estímulos ambientales con cambios observables en el comportamiento tras ser alimentado con diversas bacterias, resulta muy útil usarlo en este tipo de investigaciones ya que tiene una vida promedio corta y no cuenta con restricciones éticas para su uso. Por lo anterior, en este artículo se revisa la susceptibilidad que tiene C.elegans de infectarse con diferentes bacterias, además, ya que aún no se ha validado completamente como modelo para poner a prueba antimicrobianos se propone que este nematodo es útil como modelo In vivo para evaluar infecciones y tratamientos antibacterianos.
A Correlational Study on the Gross Domestic Product and Gross Domestic Product Per Capita of a Country and Its COVID-19 Incidence and Mortality Rates
Authors: Lopez Joseph Emmanuel G. 
Published: December 2021

Some studies had shown that there is a relationship between the state of
the economy of a country and COVID-19 incidence and mortality rates.
However, these studies are mostly done on countries that are already
developed. This study aims to find the relationship between GDP and GDP
per capita and COVID-19 incidence and mortality rates in all countries.
In addition, they will also be analyzed based on their different income
levels. The data collected are from databases from World Bank and WHO
and are analyzed through MS Excel and JASP. Spearman’s rho is used to
analyze the overall data and stratified data. It has been found that the
GDP per capita and incidence (r = .656, p <
.001) and mortality rates (r = .521, p <
.001) have a strong and moderate correlation, respectively. GDP’s
relationship with incidence (r = .295, p <
.001) and mortality rates (r = .346, p <
.001) resulted in both weak correlations. Stratified analysis resulted
in no significant relationships, except for GDP per capita’s
relationship with incidence (r = .362, p = .011) and
mortality rates (r = .348, p = .014) in low-middle
countries, which yielded both weak correlations. These results show that
there is indeed a relationship between the incidence and mortality rates
and the economic status of a country before a pandemic, however, more
factors need to be accounted for in order to help countries improve
their pandemic response in the future.
Influence of Control Precision and Prior Collaboration Experience on Trust and Cooperation in Inter-Organizational Relationships
Authors: Anderson Shannon W. , Cheng Mandy M. , Phua Yee Shih 
Published: December 2021

ABSTRACT
We investigate whether prior collaboration experience affects a focal partner's response to the precision of monitoring controls adopted by a new partner, with consequences for their goodwill trust in, and subsequent cooperation with, the new partner. We expect the partner to interpret their new partner's adoption of precise monitoring controls as either an effort to limit their autonomy or to reduce information asymmetry. The partner's experience with past partners is posited to determine which interpretation is salient, with negative (positive) experiences favoring the former (latter). We find that partners with an uncooperative (cooperative) experience exhibit lower (higher) goodwill trust in the new partner when controls are more precise. Further, prior experience moderates the indirect relation between the precision of monitoring controls and partner cooperation acting through goodwill trust. The results demonstrate the importance of prior experiences in the design of interfirm controls for current partner relationships.
Data Availability: Contact the authors.
JEL Classifications: M41.
cláusula compromissória como instrumento adequado de acesso à justiça no pós-pandemia
Authors: Ferreira Olavo Augusto Vianna Alves , Montes Netto Carlos Eduardo , Santos Filho Ronaldo Fenelon 
Published: December 2021

De acordo com o ordenamento jurídico brasileiro, as partes possuem ampla liberdade para elegerem a arbitragem como método adequado de resolução das suas disputas, restando analisar se é possível, no exercício dessa autonomia, a contratação de cláusula compromissória que permita dispor da arbitragem e, no mesmo instrumento, de outras formas de resolução de conflitos, como a justiça estatal, a depender de alguma situação específica, a exemplo de determinado contrato ou cláusula contratual ou, ainda, do valor envolvido na disputa e, em caso positivo, se esse instituto pode representar um efetivo instrumento de acesso à justiça, apresentando como justificativa a grave crise que provavelmente iremos atravessar no período pós-pandemia, o aumento da utilização da via arbitral como método adequado de solução de controvérsias e a ausência de trabalhos específicos sobre o assunto, tratando-se de uma abordagem original e inédita. O método adotado foi o hipotético-dedutivo, inferindo-se, ao final, que respeitados alguns limites, a cláusula compromissória pode configurar interessante instrumento de ampliação do acesso à justiça.
Echographic peculiarities of embryonal development in pregnant women of the group risk with genital infection
Authors: O. K. Holovachuk  
Published: December 2021

The article presents the echographic features of embryonal development in pregnant women with genital infections. The estimation of ultrasonic criteria of development of embryo was conducted in the early terms of gestation: estimation of structures of the embryo, cardiac performance indicators, presence of retrochorionic haematoma. It enabled to estimate the prognosis of pregnancy and possibility of development of placenta disfunction.
Age-dependent peculiarities of echocardiographic parameters of the heart in patients with nonalcoholic fatty liver disease
Authors: Prysyazhnyuk V. P. 
Published: December 2021

In present study echocardiographic features of the cardiovascular system in patients with nonalcoholic fatty liver disease (NAFLD) of different ages were examined. Structural and functional parameters of the heart change in nonalcoholic fatty liver patients with age: a progressive increase in the size of the left atrium, right ventricle, and decrease of ejection fraction. In young patients the formation of concentric remodeling and eccentric hypertrophy, in elderly patients – development of its concentric hypertrophy was observed. The above-mentioned requires timely use of cardio-protective drugs in the treatment of these patients.
Specific features of chronorhythmologic changes of the acid-regulating function of the kidneys under the hypofunction of the pineal gland
Authors: S. B. Semenenko  
Published: December 2021

The paper investigates the specific features of chronorhythmologic changes of the acid-regulating function of the kidneys under the hypofunction of the pineal gland (PG). It has been established that the hypofunction of epiphysis caused disturbances of the phasic structure of the acid-regulating function in relation to chronograms of the intact group of rats.