bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of Magnetic Resonance Imaging of the Chest at a Cancer Center
Authors: Duarte Braga Juliana Cristina , Fábio Dias Teixeira Diogo , Hochhegger Bruno , Rydz Pablo , Luiz Gross Jefferson , Jose Haddad Fabio , Rosa Naue Carine , Duarte Guimarães Marcos 
Published: December 2021

Objective: In the present article, we will describe the indications for chest MRI in patients diagnosed with malignancy and its relevant role in distinguishing benign from malignant lesions and in detecting metastases. Materials and methods: Single-center, retrospective, analytical imaging and chart-review study of all patients with a diagnosis of cancer who underwent chest MRI at the Imaging Department of A.C. Camargo Cancer Center from January 2014 through December 2016. Information was collected through an electronic questionnaire and exported to a Microsoft Excel spreadsheet. Data were then processed in Action Stat 3 software. Descriptive analysis was conducted with conventional measures of central tendency (mean, median, mode) and dispersion (range, variance, standard deviation, and coefficient of variation), as well as calculation of absolute and relative frequencies. Results: The leading indication for chest MRI was post-treatment follow-up. Chest MRI was most often requested by the Departments of Thoracic Surgery and Clinical Oncology. In most cases, the results of chest MRI led to maintenance of the current treatment plan rather than a change in management. Conclusion: Magnetic resonance imaging has several applications in evaluation of the chest, and can be used by various specialties and subspecialties. In the present study, post-treatment follow-up and maintenance of current therapy were the most common indication and management, respectively.
Observatório dos acidentes de transporte terrestre atendidos pelo Serviço de Atendimento Móvel de Urgência no interior de Pernambuco
Authors: Santos Thiago das Virgens , Ferreira Jessica Leticia Rodrigues , Trindade Joanis Silva , Silva Alane Macedo da , Ferreira Filho Antônio Roberto , Souto Silva Denilça , Silva Cristiane Nunes da , Martins Victor Hugo da Silva 
Published: December 2021

Os acidentes de transporte terrestre (ATT) ceifam milhares de vidas todos os anos, do mesmo modo que provocam sequelas importantes e permanentes em várias pessoas durante seu curso existencial, tendo como fatores contribuintes o uso de substâncias que alteram o nível de consciência e a imprudência nas estradas. O presente estudo objetiva-se caracterizar os ATT da cidade de Petrolina/PE, a partir da demanda atendida pelo Serviço de Atendimento Móvel de Urgência (SAMU). Trata-se de um estudo descritivo sobre acidentes ocorridos no município, alicerçado pelo total de ocorrências atendidas pelo SAMU do município durante o período de 2018. As informações foram coletadas da base de dados do SAMU. A cidade fica localizada no interior de Pernambuco e tem um grande volume de chamados para atendimento de ATT, sendo considerado um fator alarmante, haja vista que é classificado como um sério problema de saúde pública no mundo. Verifica-se que o pedido para prestação de socorro para os motociclistas tem prevalência superior a 70% em relação ao número total de ocorrências, com destaque numérico em todos os meses de 2018. Nesse sentido é necessária a adoção de medidas efetivas quanto a educação no trânsito para a comunidade, na elaboração de normas, bem como a co-responsabilização e colaboração de outros setores e comunidade, no intuito de amortizar os índices de acidentes, sequelas e óbitos.
Flow cytometric analysis of the inhibition of human basophil activation by histamine high dilutions - a replication study
Authors: Wälchli Chantal , Baumgartner Stephan 
Published: December 2021

Background: Inhibition of human basophil activation by highly diluted histamine was reported to be a reliable experimental model to examine biological effects of high dilutions. However, independent replications did not always yield concordant results.
Aims: We aimed at performing an independent replication of a former study [1] using rigorously controlled experimental conditions to minimise confounding factors.
Materials and Methods: In 20 independent experiments, human basophils were treated with highly diluted histamine (15cH, 16cH, corresponding to 10-30-10-32 M) prior to activation by fMLP (formyl-methionyl-leucyl-phenylalanine peptide). Controls were treated with analogously diluted water (15cH, 16cH). The dilutions were prepared freshly for each experiment in deionised water by successive steps of centesimal dilution and agitation (10 s vortex at high speed). Highly diluted samples were blinded and randomised. All samples were set in triplicates. Activated basophils were determined by flow cytometry using anti-CD203c. 20 independent systematic negative control (SNC) experiments were carried out to investigate possible systematic errors.
Results: No difference in basophil activation was observed between the highly diluted histamine samples and the highly diluted water controls. There was no evidence for a blood donor specificity of the results. The SNC experiments demonstrated the stability of the test system. Experimental variability within and between experiments was slightly reduced for the highly diluted histamine samples.
Discussion: This study was designed as an independent reproduction of a former study [1]. Though we strictly adopted the experimental procedure described in [1], our results do not confirm the large inhibitory effects observed for histamine 15cH and 16cH. This lack of reproducibility might be due to minor differences in the experimental design, such as blinding and randomising of the samples, which we chose to perform in order to reduce the possibility of artifacts but was omitted in the former study.
Conclusions: Laboratory independent replication of homeopathic basic research experiments is still a challenge. Assuming that the results formerly obtained with this model were not due to systematic errors, the quest identifying the crucial factors for successful reproducibility is open for future research.
Keywords: Human basophils; histamine; high dilutions; flow cytometry
Reference:
[1] Sainte-Laudy J, Belon P. Improvement of flow cytometric analysis of basophil activation inhibition by high histamine dilutions. A novel basophil specific marker: CD 203c. Homeopathy. 2006;95:3-8.
Biochemical responses induced by Biotherapics prepared from intact influenza A (H3N2) and inactivated influenza A (H3N2) virus at 12x and 30x in MDCK cells and RAW-264-7 macrophages
Authors: Siqueira Camila , De MendonÃƒÆ’Ã‚Â§a Rafaela , Da Veiga Venício , Marcondes Mariah , Grechi Juliana , Jardim-Messeder Douglas , Zancan Patricia , Galina Antonio , Couceiro JosÃƒÆ’Ã‚Â© Nelson , Holandino Carla 
Published: December 2021

Background: "Roberto CostaÃƒÂ¢Ã¢â€šÂ¬Ã¢â€žÂ¢s Biotherapics" are homeopathic remedies prepared from intact microorganisms which have been proposed for treatment of diseases like influenza.
Aim: This study aimed to compare the biochemical effects, in MDCK cells and RAW-264-7 macrophages, of biotherapics prepared from intact influenza virus diluted in water as well as from a sample of the same virus inactivated by ethanol 70% (v / v), both in the homeopathic potencies of 12x and 30x. Water 30x, non-dynamized water and cells without treatment (control cells) were used as control.
Methodology: Treatments were performed by incubating MDCK cells with DMEM medium added in a 1:10 ratio for 6 times (3 different aliquots per day) or 18 times (up to 4 aliquots per day) in each experimental situation. Each aliquot was added with an interval of at least 2 hours. After that, the mitochondrial activity of MDCK cells was analyzed by MTT assay. The effects of treatments with intact biotherapics on MDCK cells respiratory parameters were studied using high resolution respirometry (Oroboros Oxygraph-O2K). RAW-264-7 macrophages were treated with intact and inactivated biotherapic 30x (4 treatments, 24 hours) to verify the nitric oxide production. These macrophages were also submitted to MTT assay.
Results: Both biotherapic preparations 1x (intact and inactivated virus sample) were analyzed by transmission electronic microscopy. The presence of virus particles was detected when water was used as solvent. The use of ethanol as biotherapic solvent induced complete virus lysis. There was no alteration in cell osmolarity revealed by neutral red assay, when 10% of each test solution was used. Cellular viability analyzed by MTT method increased when MDCK cells were treated with 18 stimuli of inactivated biotherapic 30x when compared to intact biotherapic 30x (p0.05) were detected when these cells were compared to control cells.
The maximum respiratory capacity of MDCK cells increased after treatment with 18 stimuli of intact biotherapic 30x when compared to control cells. However, no statistically significant differences (p>0.05) induced by biotherapics in macrophage cells were observed by MTT and nitric oxide assays. Moreover, a reduction in nitric oxide was observed in macrophages treated with dynamized water when compared to control cells.
Conclusions: These results indicate that the method of biotherapic compounding (intact or inactivated virus as starting point) can modify the cellular parameters with the tendency to increase cellular response with longer treatments and higher potencies.
El plan arqueológico director de la cuenca del Navia. Balance de tres lustros de actividad arqueológica continuada en el Occidente de Asturias
Authors: Villa Valdés Ángel 
Published: December 2021

El Plan Arqueológico Director de la Cuenca del Navia es el documento por el que el Principado de Asturias ordenó entre 1997 y 2009 las intervenciones sobre el patrimonio arqueológico de los territorios del Navia-Eo, en el extremo occidental de la región. Hasta entonces, a pesar del esfuerzo económico realizado por el Gobierno Regional, los resultados no fueron en estas comarcas demasiado satisfactorios en materia de conservación del patrimonio histórico por la carencia de un proyecto que definiese los objetivos y un modelo de gestión adecuado. Por esta razón se encargó un plan director que estableciese las prioridades de intervención arqueológica en sus diversas facetas: conservación, investigación y difusión. En la presente comunicación se dará cuenta de los criterios empleados en la selección de objetivos, del tipo de intervenciones propuestas y de las vías de financiación utilizadas. Asimismo se expondrán los avances producidos mientras el plan se mantuvo vigente y las causas que motivaron su abrupta interrupción.
La valorización del yacimiento arqueológico de la Motilla del Azuer (Daimiel, Ciudad Real) a través de las nuevas tecnologías
Authors: Torres Mas Miguel , López Tercero Julio , López-Menchero Bendicho Víctor Manuel , Torrejón Valdelomar Juan , Maschner Herbert D.G. 
Published: December 2021

La aplicación de nuevas tecnologías en el campo del patrimonio arqueológico está generando la incorporación de diferentes perspectivas con respecto a su proyección, puesto que por un lado permite recoger datos desde distintas lecturas y niveles, al tiempo que ofrece fórmulas novedosas con respecto a su valorización integral.
En las siguientes líneas se va a efectuar una descripción pormenorizada de los diferentes trabajos llevados a cabo dentro de la actividad “Motilla Virtual”. Este proyecto se desarrolla a partir de un conjunto de actuaciones que van desde la digitalización 3D de todo su recinto, el diseño de una visita a través de realidad virtual, estudios de termografía y geofísica de todo el conjunto, así como trabajos de reconstrucción virtual del asentamiento durante la Edad del Bronce. De igual manera, se presentan de forma detallada los métodos elegidos, recursos empleados y resultados obtenidos, describiendo todos los aspectos o utilidades que se han puesto en funcionamiento dentro de este proyecto. Estas herramientas han permitido avanzar en la investigación, documentación, conservación y valorización de este monumento prehistórico.
Entre culturème et identitème : le processus de patrimonialisation du « voile » en France
Authors: Dahou Chahrazed 
Published: December 2021

Ce qui caractérise la notion d’identitème est la promotion médiatique et politique d’un mot ou d’un groupe de mots que l’usage transforme en référents identitaires. Qu’on le choisisse ou qu’on le refuse, qu’on le loue ou qu’on le stigmatise, qu’on le banalise ou qu’on le diabolise, le voile, dans son processus de construction comme un identitème, semble avoir franchi toutes les étapes de patrimonialisation nécessaires à un mot pour s’établir comme un identitème. En prenant en compte les promotions médiatiques et scientifiques des « affaires du voile », quasi-permanentes en France depuis la fin des années 80, il s’agit de mettre en scène, à travers une enquête socio-linguistique, le processus de patrimonialisation par lequel, un signe ethno-socioculturel « le voile » est devenu un identitème en France.
ESKİ ANADOLU TÜRKÇESİYLE YAZILMIŞ BİLİNMEYEN İKİ AYRI SATIR ALTI TÜRKÇE KUR’AN TERCÜMESİ
Authors: AKPINAR Ahmet 
Published: December 2021

Eski Anadolu Türkçesinin 13. yüzyıldan itibaren yazı dili olarak kullanılmaya başlanmasıyla günlük ibadetlerde okunan kısa sûreler (Fatiha, İhlas, Yasin, Tebareke vd.) Türkçeye tercüme edilmiştir. Beylikler dönemine tesadüf eden bu tercüme faaliyetleri Kur’an’ın bir bütün hâlinde Oğuz Türkçesine tercümesinin de önünü açmıştır. Anadolu Türkçesine yapılan ilk Kur’an tercümeleri Arapça bilmeyenlere Kur’an âyetlerinin manasını öğretmek amacıyla satır arasına Kur’an âyetlerinin meali ya da meal-tefsiri yazılarak yapılmıştır.
Bu çalışmada, iki yeni Eski Anadolu Türkçesi Kur’an tercümesi (AÜ EY1059 ve O6 Mil Yzb 50) tanıtılarak bu yazmalardaki sözvarlığı ilk olarak dönemin diğer tercümeleriyle karşılaştırılmıştır. Bu karşılaştırmadan elde edilen sonuca göre Eski Anadolu Türkçesi Kur’an tercümeleri sözvarlığı bakımından iki ayrı grupta toplanmıştır. Sonuç olarak, nüsha tavsifi yapılan bu iki tercümenin 1. grupta yer alan tercümelerle sözvarlığı bakımından örtüştüğü görülmüştür. Bunun yanında, sözvarlığı bakımından 1. ve 2. grupta yer alan Kur’an tercümeleri Doğu Türkçesiyle yazılmış (Hekimoğlu, Özbekistan, Meşhed-1007) Kur’an tercümeleriyle de karşılaştırılmıştır. Bu karşılaştırmaya göre, 2. grupta yer alan Kur’an tercümelerinin sözvarlığı bakımından Harezm Türkçesiyle örtüştüğü, ancak bu grupta yer alan Bursa ve Önder nüshalarının sözvarlığının örtüşmediği görülmüştür. Bu durum, 2. grupta yer alan Eski Anadolu Türkçesi Kur’an tercümelerinin Harezm Türkçesiyle yazılmış bir ara tercümeden kopyalandığını gösterirken, Bursa ve Önder nüshalarının üçüncü bir ara nüshadan kopyalanmış olabileceğini de düşündürmektedir.
DAĞISTAN’DAN ÇİN’E UZANAN İLİM YOLCULUĞU: ÇİN VÂİZİ DAĞISTANLI SEYYİD MEHMET TAHİR EFENDİ (Hayatı, Eserleri ve İstiklal Mahkemesinde Yargılanma Süreci)
Authors: YILDIZ Esra 
Published: December 2021

Osmanlı Devleti, miras aldığı İslam kültürünü uzak doğu ülkelerinden Çin’e kadar taşımıştır. “İttihâd-ı İslam’ı” sağlamak ve Müslüman halkı “İslam Halifesi”ne bağlamak için bu bölgelere ilim adamları göndermiştir. Osmanlı Devleti ile Uzak Doğu arasında bir nevi köprü vazifesi gören ulema, ailelerinden uzakta birçok sıkıntıya göğüs germiş ve gittikleri yerlerdeki halkın manevî destekçileri olmuşlardır. Çin’e gönderilen ilim heyeti içerisinde yer alan Ahmed Hüsameddin Dağıstânî’nin halifelerinden ve Hz. Peygamber’in nesebinden Seyyid Mehmet Tahir Efendi, kendisini ilme ve Kafkasya Müslümanlarının maruz kaldığı zulme karşı direniş mücadelesine adamıştır.
Bu çalışmada, “Çin Vaizi Dağıstanlı Seyyid Mehmet Tahir Efendi’nin Uzak Doğu’daki İslam Birliği Politikasına Katkıları” ele alınmıştır. Şeyhülislâmlığın ve Osmanlı ulemasının temel kaynaklarından birisi olan Meşihat Arşivi’ndeki defter ve belgeler ışığında Seyyid Mehmet Tahir Efendi’nin eğitim ve hizmet hayatı, nesebi, ilim yolculuğu ve Çin’de vazifelendirilmesi, yazdığı eser ve makaleleri, Yeni Kafkasya Gazetesi, Şimali Kafkasya Cemiyeti ve Lozan Mahkûm Milletler Konferansındaki faaliyetleri ayrıntılı izah edilmiştir. Böylece Dağıstan’dan Çin’e uzanan ilim ve kültür yolcusu Seyyid Mehmed Tahir Efendi’nin mücadelesi ilim dünyasına tanıtılmıştır.
Rasch Model: Identifikasi Kemampuan Habits Of Mind Peserta Didik SMA
Authors: Mulvia Rahmadhani , Ulfa Sania , Ady Widi Nugraha 
Published: December 2021

Tujuan penelitian adalah untuk mengidentifikasi kemampuan habits of mind yang dimiliki peserta didik SMA dengan analisis Rasch Model. Habits of mind adalah kemampuan perilaku cerdas paling tinggi yang dimiliki peserta didik sebagai hasil belajar jangka panjang pada proses pembelajaran sehingga dijadikan indikator kesuksesan dalam penyelesaian masalah. Habits of mind terbagi menjadi tiga kategori: berpikir kritis, berpikir kreatif dan regulasi diri. Untuk mencapai tujuan, Rasch Model digunakan untuk menganalisis kemampuan habits of mind peserta didik SMA. Hal ini dikarenakan, Â Rasch Model memiliki asumsi invariansi parameter artinya parameter butir soal tidak bergantung pada parameter kemampuan peserta didik dan parameter kemampuan peserta didik tidak bergantung pada parameter butir soal. Penelitian ini menggunakan metode deskriptif kuantitatif dengan partisipan 36 peserta didik SMA yang berumur 16-17 tahun dan dipilih secara random sampling. Instrumen yang digunakan adalah kuesioner yang terdiri dari 15 pernyataan mencakup setiap kategori habits of mind dan dinyatakan layak oleh ahli. Hasilnya, kemampuan habits of mind yang dimiliki peserta didik SMA berbeda untuk setiap kategori. Sebagian besar dari partisipan memiliki habits of mind-berpikir kritis dan habits of mind-berpikir kreatif di atas rata-rata dibandingkan habits of mind-regulasi diri. Oleh karena itu, untuk meningkatkan habits of mind dapat melalui pembelajaran dengan strategi asesmen formatif yaitu feedback, self-assessment dan peer-assessment.
فقہ اسلامی میں بیع سلم کاتصور اورمروجہ اسلامی مالیاتی نظام میں بیع سلم کے استعمال سے متعلق اشکالات:ایک فقہی مطالعہ
Authors: Siddique Muhammad Abubakar 
Published: December 2021

The sharī‘ah invalidates the sale of non-existing items, but salam sale was exceptionally permitted to avoid interest-based financing in commercial as well as non-commercial transactions. Salam sale is an Islamic forward sale contract, which authorizes selling something that is not present during the time of the contract. Salam is a sale agreement whereby the seller receives full price in advance and goods are delivered at a future date. Moreover, it is free from uncertainties and exploitation that is usually involved in interest-based financing. Besides the agriculture sector, currently, this instrument is also being used in the manufacturing sector where the manufacturer would need financing to produce products and/or to buy raw materials. Modern financial innovations introduced different uses of salam sale such as parallel salam, currency salam, salam sukūk etc. There are different fiqh issues related to such uses of salam in modern financial sectors. This article elaborates on the economic importance and conditions that are necessary and sufficient to makethe contract valid from the perspective of the sharī‘ahand also appraises some of the key issues related to modern practices regarding salam.
ANALISIS SISTEM PELEPASAN INFORMASI REKAM MEDIS DALAM MENJAMIN ASPEK HUKUM KERAHASIAAN REKAM MEDIS DI RUMAH SAKIT IMELDA PEKERJA INDONESIA MEDAN TAHUN 2018
Authors: Noviar Panggabean Terry , Sianipar Elisa 
Published: December 2021

Akreditasi rumah sakit adalah pengakuan terhadap rumah sakit yang diberikan oleh lembaga independen penyelenggara akreditasi yang ditetapkan oleh Menteri.Komisi Akreditasi Rumah Sakit (KARS) adalah lembaga independen pelaksanan akreditasi rumah sakit.RS Sufina Aziz Medan sedang mempersiapkan akreditasi 2012, berdasarkan survey awal peneliti mengetahui ketidakamanan ruangan rekam medis salah satunya dengan tidak adanya pintu pembatas diruangan rekam medis untuk menjaga keamanan informasi pasien sehingga tidak sesuai dengan standar MKI 11.Penelitian ini dilaksanakan di Rumah Sakit Sufina Azis Medan pada bulan Juni tahun 2016 dengan jenis deskriptif.Populasi dalam penelitian ini adalah seluruh petugas rekam medis sebanyak 9 orang. Data dikumpulkan dengan caraobservasi dan angket. Hasil dari persentase menunjukkan bahwa minoritas responden yang melaksanakan akreditasi versi 2012 pada MKI 11 sebanyak 3 orang (33,3%) dan mayorits responden yang melaksanakan akreditasi versi 2012 pada MKI 11 kategori cukup baik sebanyak 6 orang (66,7%). Dari hasil penelitian ini disarankan agar dapat meningkatkan kualitas pengetahuan mengenai keamanan informasi pasien dan integritas data dijaga dirumah sakit. Sehingga dapat terlaksananya penyelenggaraan akreditasi sesuai dengan prosedur yang ditetapkan oleh tim kars (komite akreditasi rumah sakit).
ANALISIS PENYEBAB UNCLAIMED BERKAS BPJS PASIEN RAWAT INAP DI RUMAH SAKIT UMUM IMELDA PEKERJA INDONESIA (RSU IPI) MEDAN
Authors: Valentina  , Niat Sehati Halawa Merlin 
Published: December 2021

Pending atau sering disebut dengan unclaimed yang artinya tidak terklaim atau tertunda. Hal ini disebabkan terdapat kasus yang ditatalaksanakan di rumah sakit tersebut diragukan kesimpulan medisnya karena ketidakcocokan atau ketidaklengkapan data-datanya. Tujuan penelitian ini untuk menganalisis penyebab unclaimed berkas BPJS pasien rawat inap berdasarkan identifikasi input dan proses. Jenis penelitian ini menggunakan metode kualitatif dengan fenomenologi. Waktu penelitian dilakukan pada bulan Februari-Juli 2018 di RSU Imelda Pekerjaan Indonesia Medan. Populasi yaitu rekam medis BPJS rawat jalan yang dipending pada bulan Februari-Juli 2018 sebanyak 490 berkas. Sampel diambil secara proposional stratified random sampling yang berjumlah 83 berkas. Informan kunci berjumlah 6 orang yang terdiri dari 1 orang kepala ruangan BPJS RSU IPI,3 orang petugas koder BPJS RSU IPI dan 2 orang petugas administrasi BPJS. Data dikumpulkan melalui wawancara dan observasi. Untuk analisis data dirangkum secara deskriptif melalui reduksi data, penyajian dan penarikan kesimpulan. Hasil penelitian ini menunjukkan penyebab unclaimed berkas BPJS pasien rawat inap di Rumah Sakit Umum Imelda Pekerja Indonesia (RSU IPI) Medan adalah jumlah SDM, sarana, teknologi, perencanan berupa ketersediaan SOP, dan evaluasi. Berdasarkan 83 berkas BPJS yang terpending ada 45% berkas BPJS dikarenakan dari kesalahan pengkodingan, 22% dikarenakan dari indikasi medis dan 33% dikarenakan administrasi. Disarankan untuk pihak rumah sakit agar menambah jumlah SDM, perbaikan terhadap sarana dan teknologi, perencanaan dan evaluasi sehingga dapat menurunkan jumlah unclaimed berkas BPJS pada rumah sakit.