bluuebunny/crossref_metadata_2025_split huggingface dataset:
Refinement and Extension of COSMO-RS-Trained Fragment Contribution Models for Predicting Partition Properties of C10–20 Chlorinated Paraffin Congeners
Authors: Endo Satoshi 
Published: March 2021

COSMO-RS-trained fragment contribution models (FCMs) to predict partition properties of chlorinated paraffin (CP) congeners were refined and extended. The improvement includes (i) the use of an improved conformer generation method for COSMO-RS, (ii) extension of training and validation sets for FCMs up to C20 congeners covering short-chain (SCCPs), medium-chain (MCCPs) and long-chain CPs (LCCPs), and (iii) more realistic simulation of industrial CP mixture compositions by using a stochastic algorithm. Extension of the training set markedly improved the accuracy of model predictions for MCCPs and LCCPs, as compared to the previous study. The predicted values of the log octanol/water partition coefficients (Kow) for CP mixtures agreed well with experimentally determined values from the literature. Using the established FCMs, this study provided a set of quantum chemically based predictions for 193 congener groups (C10–20, Cl0–21) regarding Kow, air/water (Kaw), and octanol/air (Koa) partition coefficients, subcooled liquid vapor pressure (VP) and aqueous solubility (Sw) in a temperature range of 5–45 °C as well as the respective enthalpy and internal energy changes.This is a preprint version and has not yet been peer reviewed.
Comparing efficacy and safety of sodium valproate with propranolol in paediatric migraine prophylaxis
Authors: Varsha Gajbhiye  , Lamture Yashwant R  , Sadama Quazi  
Published: March 2021

Migraine is a common disorder of the paediatric age group. Propranolol has been used in prophylaxis for migraine. The use of Sodium valproate in the prophylaxis of migraine is not known. It is postulated that it increases the level of GABA in the brain that will decrease events related to migraine in the cortex. All parents of the patient were advised to keep diaries for noting time, date, severity and duration of headache during the study period, which was for a period of 6 wks. The decreased frequency of headache more than in Group A was 68% and propranolol group was 68.89%. In group A(sodium valproate), patients showed a reduction in headache duration and 52% in Group B. 20% of them headache free in Group A and 18% in Group B. Decrease in the severity of headache in Group A was 52% while 50% in Group B. The mean headache frequency before and after treatment was reduced from 8 to 2.5 attacks per month in group A and from 8.2 to 2.6 in group B. The t-value is 11 for group A. Sodium valproate is more effective and safer in migraine prophylaxis as compared with propranolol.
"You have no idea": Women in Architecture in the Eighties
Authors: Matthewson Gill 
Published: March 2021

A number of moves in the seventies had meant that more women than ever before were in architecture schools and by the eighties they were flooding into the profession. Over the decade their numbers quadrupled (as measured by registration) as women moved from the exception to the norm. But their impact was variable. This paper will try to tease out that impact from women-only practices to support groups to what they published to moves away from the profession.
Pendampingan Pengembangan Komoditas Hortikultura Unggulan di Dataran Medium Desa Stiling, Lombok Tengah
Authors: Sarjan M. , Nikmatullah Aluh , Windarningsih Mery , Hadi Agus Purbatin 
Published: March 2021

Di wilayah Lombok Tengah sudah mengembangkan berbagai tanaman buah, holtikultura dan beberapa tanaman unggulan lokal di dataran rendah . Sementara dataran medium yang mempunyai kekhasan tersendiri belum dikembangkan terutama untuk budidaya tanaman tertentu seperti kentang, wortel , paprika, bawang putih dan mentimun jepang yang sementara ini hanya ditanaman di dataran tinggi Sembalun. Oleh karena itu pada kegiatan ini dilakukan pendampingan budidaya tanaman tersebut di dataran medium Stiling , Kecamatan Batukeliang Utara, Lombok tengah . Metode yang digunakan pada kegiatan ini adalah metode action riset dengan melibatkan kelompok tani selama kegiatan yang diawali dengan penyukluhan teknisk budidaya , dilanjutkan dengan kegaiatn demplot penanaman kentang, wortel, paprika , bawang putih dan mentimun jepang. Hasil pendampingan ini menunjukan Kegiatan Pendampingan Pengembangan Komoditas Hortikultura di dataran Medium Desa Stiling, Lombok Tengah sangat didukung oleh pemangku Kebijakan , Kepala Dinas Pertanian dan oleh Kelompok Tani setempat. Tanaman Kentang, wortel, bawang putih, paprika dan mentimun jepang dapat tumbuh baik di dataran medium Stiling, Lombok Tengah. Petani peserta telah mendapatkan pengetahuan dan keterampilan teknik budidaya tanaman yang dicoba pada kegiatan ini yaitu budidaya kentang, wortel, bawang putih, mentimun jepang dan paprika. Untuk meningkatkan hasil guna dari pendampingan ini disarankan perlu dukungan yang pendampingan dari pihak pemda Lombok Tengah agar kegiatan pengembangan komoditas hortikultura unggulan dataran medium dapat berlanjut sesuai dengan harapan para petani. Perlu mempertimbangkan saat tanam yang tepat untuk penanaman kempat komoditas yang ingin dikembangkan di lokasi kegiatan, dan sesuai dengan karakteristi musim setempat sebaiknya memulai penanaman pada ahir musim hujan atau sekitar bulan Maret / April Disarankan untuk memperhatikan secara serius masalah ganguan hama dan penyakit tanaman yang sering menjadi kendala dalam budidaya komoditas hortikultura ( terutama kentang , tumun jepang dan bawang putih) dan dilakukan pengendalian yang tepat dan efektif berdasarkan prinsip Pengelolaan Hama Terpadu. Diharapkan hasil kegiatan ini akan meningkatkan pendapatan petani dan masyarakat sekitar, di samping untuk meningkatkan kenekaragaman homoditas hortikultura potensial di dataran medium sebagai alternative usaha tani di kawasan agrowisata Lombok Tengah . Komoditas unggulan seperti kentang, wortel dan paprika diharapkan menjadi andalan untuk dipasarkan di kawasan wisata lainnya seperti di pantai Selatan Mandalika.
Diagnostic Accuracy of Frozen Section in Musculoskeletal Tumors
Authors: Fahad Shah , Umer Masood 
Published: March 2021

ABSTRACT

Introduction:
Musculoskeletal tumors are rare group of disorders. To reach a diagnosis requires detailed medical history, physical examination, radiological investigations and histopathological correlation. Intra operative consultation plays an important role in the management of soft tissue tumors. However, there is a considerable lack of literature evaluating the diagnostic accuracy of frozen sections in musculoskeletal tumors. This study is aimed because no local data is available on the accuracy of frozen section in musculoskeletal tumors and frozen section allows intraoperative diagnosis.

Objective:
To evaluate the diagnostic accuracy of intra-operative frozen sections for musculoskeletal tumors i.e, bone and soft tissue benign and malignant.

Study Design:
Descriptive cross sectional study.

Setting:
Section of Orthopaedic, Department of Surgery, The Aga Khan University Hospital.

Duration of Study:
From 12th October 2018 to 5th August to 2019.

Materials and Methods:
A cross sectional descriptive study was designed to evaluate the Diagnostic accuracy of frozen section in musculoskeletal tumors at a tertiary care hospital, Karachi. All the patients meeting the inclusion criteria were enrolled in the study and sensitivity, specificity, PPV, NPV and diagnostic accuracy were calculated for frozen section keeping permanent section as gold standard.

Results:
Of the total 88 patient 48 (54.54%) were male and 40 (45.45%) were female. Mean age was 30.75 years (5–80 years). 63(71.59%) patients have bone tumors while 25(28.40%) have soft tissue tumors. 50(56.81%) patients have tumour involving lower extremity, 23(26.13%) have upper extremity tumors and 15 (17.04%) have tumour involving pelvis.
Overall sensitivity of frozen section for benign and malignant tumour of bone and soft tissue was 96.66%, specificity was 100%, positive predictive value 100%, and negative predictive value 93.33% and accuracy was 97.72%.

Conclusion:
Frozen section serves as an invaluable and accurate tool in the intraoperative evaluation of musculoskeletal tumors. A diagnosis of musculoskeletal tumor by the frozen section method is highly reliable.
A systematic scoping review of the impacts of community food production initiatives in Kenya, Cameroon, and South Africa
Authors: Hutton Gráinne B , Brugulat-Panés Anna , Bhagtani Divya , Mba Camille Maadjhou , Birch Jack M , Shih Hueyjong , Okop Kufre , Muti Monica , Wadende Pamela , Tatah Lambed , Mogo Ebele , Guariguata Leonor , Unwin Nigel 
Published: March 2021

Background Even before the COVID-19 pandemic, one in two people in Africa were food insecure. The burden of malnutrition remains high (e.g. childhood stunting, anaemia in women of reproductive age) or are increasing (e.g. overweight and obesity). A range of coordinated actions are required to improve this situation, including increasing local food production and consumption. The aim of this review was to provide a systematic and comprehensive overview of recently published research into the health, social, economic, and environmental impacts of community food production initiatives (CFPIs) in Kenya, Cameroon and South Africa. Methods We searched eight electronic databases covering health, social, environmental, economic and agricultural sciences. Primary research studies published from 1 January 2014 to 31 December 2018 were considered. Data on geographic location, study design, type of CFPI and the impacts assessed were abstracted from eligible articles. Findings We identified 4828 articles, 260 of which required full-text review and 118 met our eligibility criteria. Most research was conducted in Kenya (53.4%) and South Africa (38.1%). The categories of CFPIs studied were (in order of decreasing frequency): crop farming, livestock farming, unspecified farming, fisheries, home / school gardens, urban agriculture, and agroforestry. The largest number of studies were on the economic and environmental impacts of CFPIs, followed by their health and social impacts. The health impacts investigated included food security, nutrition status and dietary intake. One study investigated the potential impact of CFPIs on non-communicable diseases. Over 60% of studies investigated a single category of impact. Not one of the studies explicitly used a theoretical framework to guide its design or interpretation. Conclusions Our findings on research studies of CFPIs suggest the need for a greater focus on interdisciplinary research in order to improve understanding of the relationships between their health, environmental, economic, and social impacts. Greater use of explicit theoretical frameworks could assist in research design and interpretation, helping to ensure its relevance to informing coordinated intersectoral interventions and policy initiatives.
Knowledge and Attitude of Nursing Staff on Baby-friendly Hospital Initiative Practices in a Tertiary Hospital
Authors: Mathema Smriti , Shrestha Sabina 
Published: March 2021

Background: Within a hospital setting, health professionals play a key role in providing the right information on breastfeeding and often this source are the nurses who have the primary opportunity to counsel, support and educate mothers on breastfeeding. The Baby Friendly Health Initiative (BFHI) has helped to motivate facilities providing maternity and newborn services worldwide to better support breastfeeding.
Objective: The aim of this study is to help identify the knowledge gaps on the BFHI practices among nursing staff in a tertiary care center in Kathmandu.
Methodology: A total of 27 nursing staff who encounter pregnant women admitted in the hospital up until post-delivery discharge were selected for the study. Data on knowledge of baby-friendly hospital initiative and attitude towards breastfeeding practices was collected using a structured interview between October and December 2019. Statistical analysis was done using SPSS version 20.
Results: Only 41% were acquainted with the ten steps to successful breastfeeding of BFHI, out of whom more than half (55%) had a good level of knowledge. Majority of the participants showed a fairly correct attitude towards BFHI practices, except for the belief that there is no harm in introducing pre-lacteal feeds to babies. The opinion on demand feeding and the time of introduction of complementary feeding seemed to vary.
Conclusion: There is an urgent need to re-evaluate the present knowledge of our nursing staff and to ensure they impart the right information. The only way to achieve this is through advocacy and training to promote, support and protect breastfeeding.
Recurrent dermatofibrosarcoma protuberans: A Case report and literature review
Authors: K C Hari Bahadur , Shrestha Jayan Man , Lohani Ishwar 
Published: March 2021

Introduction: Dermatofibrosarcoma protuberans is a rare soft tissue tumor which is known for its high recurrence behavior. Adequate excision and regular follow up is the current treatment modality.
Case report: 42 years male developed multiple nodular lesions on anterior chest wall for which he underwent surgical therapy for five times, but tumor recurred on every occasion. Wide local excision and split skin grafting was performed with negative margin on histopathology.
Conclusion: Dermatofibrosarcoma protuberans has high recurrence rate due to its infiltrative growth pattern. Regular follow up is required after surgery during early post-operative period to detect any recurrences.
Attitude of first mature ages to zumba dance aerobics
Authors: Kovaleva N. V. , Ieremenko N. P. , Kovalev V. A. 
Published: March 2021

The article considers the factors that affect the attitude of women of the first period of adulthood to dance aerobics. The significance of zumba dance aerobics classes is substantiated.
Zumba is a physical activity that has been practiced in the world for almost 30 years. However, it has become very popular in the last decade. Most gyms offer this dance or something similar, as ZUMBA was patented by its inventor Alberto Perez.
Zumba for weight loss is based on various Latin American rhythms, such as bachata, salsa, mirenga, cumbia and samba.
These dances are combined with aerobic exercises to effectively support weight loss.
During zumba, your body burns a lot of calories, toning muscles and gaining flexibility. In addition, these dances help to learn Latin rhythms in an interesting and accessible way for everyone, even children. Now there are variants of zumba in the water. Zumba a combines aerobic exercise and anaerobic. That is, in addition to intense exercise that makes you sweat, do not forget to strengthen muscles. The more muscle you have, the more you speed up your metabolism and the more calories you burn.
The urgency of the topic is due to various factors of modern society, because scientific and technological progress and growing urbanization are constantly accelerating the life of the population, resulting in growing needs for recovery, relaxation and the desire to indulge in a favorite pastime. Therefore, in today's world, fitness is really increasingly used to improve well-being, raise morale and to adjust your body to further work.
The survey was conducted for one month on the basis of the fitness club "Sport & Spa" in Kiev. 20 women aged 20 to 30 took part in the survey.
The data analysis was used to identify the needs and motivations of women and to assess the attitudes of early adult women to Zumba classes.
Changes in some anthropometric indicators in sportsman-athletes at the stages of long-term training
Authors: Kotko Dina , Goncharuk Natalia , Shevtsov Serhii , Pytro Lyudmila , Levon Maria , Oksamitna Lyudmila 
Published: March 2021

Literature data previous own studies indicate changes in anthropometric parameters in athletes due to the intensity and duration of exercise. An assessment of changes in some anthropometric indicators in athletes at the stages of long-term training. The paper summarizes the results of a survey of 53 athletes (athletes) at the stages of long-term training. The study involved 3 groups of athletes: 1st group - (15 athletes) - athletes at the stage of specialized basic training. 2nd group (28 athletes) - athletes in preparation for higher sporting achievements. 3rd (10 athletes) - athletes at the stage of maximum realization of their individual capabilities. The age of the athletes is 18-20 years, the track and field experience is 5-10 years.
The anthropometric study included: Quetelet's weight-height index, the relative amount of muscle tissue, the absolute amount of the bone component of the body. The indicators were determined according to generally accepted methods. The results of anthropometric survey are processed by variational-statistical methods. The study found that the competitive result of athletes depends significantly on physical development and data of athletes. Those athletes can be considered the most promising, who have high anthropometric performance. At the initial stage of selection more attention is paid to motor abilities, and during selection to sports improvement groups preference is also given to the functional capabilities of the athlete.
Theoretical bases of studying the concept of health and healthy lifestyle as universal values
Authors: Fotynyuk Vladimir 
Published: March 2021

The article analyzes and summarizes the literary sources and documentary materials of individual authors on the problem of the concept of health and a healthy lifestyle, characterizing the formation of knowledge and ideas about health as a value, positive activity in maintaining a healthy lifestyle. Awareness of the attitude to health, the formation of skills and abilities to strengthen and maintain health, contributes to a healthy lifestyle and a positive change in behavior for a long time, as a complex personality neoplasm of a person.
The problem of health, its social, medical, pedagogical, psychological aspects have received state significance and require additional activation of the search for new effective directions in the development of health-forming technologies. Today, the state of health is one of the most important indicators of the healthy potential of the nation, therefore, its preservation and strengthening are of priority importance. A person's lifespan is largely determined by how effectively he can use the tools at his disposal. Lifestyle is a good example: lack of physical activity, bad habits and poor diet can cause various health problems.
As you know, it is a healthy person who is able to most effectively create significant spiritual and material values, generate new ideas and creatively solve them. Health is one of the fundamental human values. At the same time, the system of stable beliefs is not inherent in all, some of them cannot independently determine their position on a healthy lifestyle as a vital value of health.
Pertanggungjawaban Pidana Terhadap Pelaku Pembakaran Hutan Di Provinsi Jambi
Authors: Nggeboe Ferdricka , Iswanto Reza , Puspita Sriayu Indah 
Published: March 2021

Pembakaran hutan di Provinsi Jambi dari tahun ke tahun terus mengalami peningkatan sehingga mengakibatkan kabut asap yang begitu tebal yang menyelimuti Provinsi Jambi. Oleh karena itu, selain akibat dari kebakaran hutan tersebut yaitu mengakibatkan kabut asap yang tebal, kebakaran hutan juga mengakibatkan berbagai macam makhluk hidup seperti tumbuhan dan hewan mengalami kepunahan sehingga terhadap pelaku kebakaran hutan tersebut harus dipertanggungjawabkan secara pidana mengingat bahaya yang ditimbulkannya begitu besar. Namun, walaupun telah banyak menimbulkan kerugian terhadap masyarakat Provinsi Jambi, tetapi belum ada satu perusahaan yang dijatuhkan sanksi pidana, hanya berupa penyegelan terhadap perusahaan. Selain itu juga, faktor yang mempengaruhi terwujudnya pertanggungjawaban pidana pelaku pembakaran hutan di Provinsi Jambi adalah belum ada ketegasan dari pemerintah Provinsi Jambi maupun aparat penegak hukum untuk menjatuhkan sanksi pidana, bahkan pemerintah Provinsi Jambi dan penegak hukum masih belum dapat membuktikan kesalahan para pelaku pembakaran hutan dan lahan. Untuk itu, upaya yang akan datang terkait dengan pertanggungjawaban pidana terhadap pelaku pembakaran hutan di Provinsi Jambi adalah pemerintah Provinsi Jambi maupun aparat penegak hukum harus bertindak tegas terhadap pelaku pembakaran hutan berupa penjatuhkan sanksi pidana, dan juga berupaya melakukan penyuluhan hukum sekaligus melibatkan masyarakat setempat untuk pelaporan terkait dengan ada pelaku pembakaran hutan agar mendapatkan sanksi pidana sebagaimana dalam Undang-Undang Nomor 32 Tahun 2009 Tentang Perlindungan Dan Pengelolaan Lingkungan Hidup.
Kemampuan POLRI Mempersiapkan Teknis Personil Penyidik Tindak Pidana Lingkungan Hidup
Authors: Sumaidi Sumaidi 
Published: March 2021

Salah satu tindak pidana adalah Pengrusakan dan pencemaran lingkungan hidup yang sampai saat ini sangat membawa dampak bagi masyarakat, maka dari itu diperlukan penegakan hukum terhadap kasus-kasus yang tergolong tindak pidana lingkungan hidup.Kemampuan penegak hukum sangat penting dalam melakukan penyidikan dan penyelidikan terhadap tindak pidana lingkungan hidup. Penyidik lingkungan hidup, selain diharapkan memiliki kemampuan teknis yang memadai dalam pengumpulan bukti-bukti atas terjadinya suatu tindak pidana di bidang perlindungan dan pengelolaan lingkungan hidup, juga diharapkan memiliki pemahaman yang baik atas peraturan perundang-undangan yang berlaku, sekaligus mampu menjaga integritas, kredibilitas, dan kode etik dalam melaksanakan tugas utamanya, yaitu mencari kebenaran dan menegakkan keadilan demi melindungi kepentingan pelestarian fungsi lingkungan hidup.
Clinico-Haematological Study of Pancytopenia
Authors: Reshma Samira Taufique , Giti Susane , Chowdhury Shahed Ahmed , Rabbani Mohammad Golam , Kabir Mohammad Iqbal , Rabby Md Atiqul Islam 
Published: March 2021

Introduction: Pancytopenia is a clinical condition, which refers to a combination of anaemia, leucopenia and thrombocytopenia. It often poses diagnostic challenge to physician and the knowledge of accurate etiologies of this condition is crucial in the management of the patient.
Materials and Methods: The study was a prospective study done over a period of October 2011 to December 2011 and 50 patients were evaluated clinically along with haematological parameters, bone marrow aspiration and wherever required, a trephine biopsy was performed in Haematology department of Armed forces institute of pathology (AFIP), Dhaka cantonment, Dhaka. In all patients, a detailed relevant history along with a physical examination was done and data was collected using pre designed proforma.
Results: Among the 50 cases studied, age of the patients ranged from 3 to 80 yrs with a mean age of 37.5 yrs and male predominance. Fever and generalized weakness were the most common symptoms. The commonest physical findings were pallor followed by splenomegaly and hepatomegaly. Anisopoikilocytosis and relative lymphocytosis was the most prominent peripheral blood findings in patients. The commonest cause of pancytopenia was Aplastic anaemia (36%), followed by Myelodysplastic syndrome (18%), visceral leishmaniasis (12%), Megaloblastic anaemia (8%), Acute leukaemia (6%), Myelofibrosis (4%), Multiple myeloma (4%), Hypersplenism (4%), Malaria (2%).
Conclusion: As a large number of pancytopenic patients have a reversible aetiology, early & proper diagnosis may be life saving. Maximum diagnostic yield can be achieved by correlation with clinical findings & laboratory parameters.
Medicine Today 2021 Vol.33(1): 12-18