bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of Oxidative Stress Indicators in Polish Patients With Prostate Cancer
Authors: Drozdz-Afelt Joanna Maria , Koim-Puchowska Beata Barbara , Kaminski Piotr 
Published: June 2021

Abstract
Aims: The aim of the study was to analyze the activity of antioxidant enzymes (glutathione S-transferase, catalase, superoxide dismutase) in order to determine the role of detoxification mechanisms in prostate cancer. The concentration of malondialdehyde, which is an indicator of lipid peroxidation in cancer patients, was also tested.Methods: The activities of superoxide dismutase (SOD), catalase CAT and glutathione S-transferase (GST ) were measured using ready-made kits; lipid peroxidation intensity was determined by the thiobarbituric acid method.Results: Superoxide dismutase was the only enzyme among antioxidant and detoxification enzymes for which a statistically significant difference in activity was found between the studied groups [1.4 U * ml-1 in patients vs. 1.6 U * ml-1 in control]. No statistically significant differences were found for two other biomarkers of antioxidant activity (GST, CAT). There were also no statistically significant differences in the concentration of MDA between the group of men with prostate cancer and the control group.Conclusion: The lower SOD activity in men with prostate cancer may be due to a deficiency in their antioxidant defense system.
The Effect of the PARK16 rs11240572 Variant on Brain Structure in Parkinson's Disease
Authors: Gu Lu-yan , Dai Shao-bing , Zhou Cheng , Gao Ting , Wu Jing-jing , Fang Yi , Guan Xiao-jun , Guo Tao , Zheng Ran , Jin Chongyao , Xu Xiao-jun , Song Zhe , Tian Jun , Yin Xinzhen , Zhang Min-min , Zhang Bao-rong , Yan Yaping , Pu Jiali 
Published: June 2021

Abstract
Background
Increasing evidence suggests that genetic factors play a key role in the development of Parkinson's disease (PD). The variant rs11240572 in the PARK16 gene locus is strongly associated with PD. However, its effect on the pathogenesis of PD is yet to be clarified.
Objective
To explore the effect of the PARK16 rs11240572 variant on brain structure in PD patients.
Methods
A total of 51 PD patients were enrolled in the study and genotyped for the rs11240572 variant. Clinical assessments and MRI scans were conducted across all participants. Voxel-based morphometry (VBM) was used to investigate gray matter volume (GMV) of the whole brain between these two groups. Correlation analysis was performed to identify the relationships between GMV and clinical features.
Results
There were 17 rs11240572-A variant carriers and 34 non-carriers, with no significant demographic differences between these two groups. Compared with non-carriers, rs11240572-A carriers showed increased GMV in left caudate nucleus and putamen, but decreased GMV in left superior temporal gyrus and supramarginal gyrus. In non-carriers, left basal ganglia GMV was positively correlated with UPDRS III (r = 0.365, p = 0.040) and bradykinesia (r = 0.409, p = 0.020), but negatively correlated with MMSE (r = -0.391, p = 0.027). When reduced the sample size to the level of the carrier sample, we still found the same correlations in the non-carrier group. However, no correlation was found between the altered GMV and clinical features in the carriers.
Conclusions
Our study showed that the PARK16 rs11240572 variant affects the brain structure of patients with PD, especially in the basal ganglia and temporoparietal cortex. This indicated that this variant might play an important role in the pathogenesis of PD.
Microvirga Amygdalina sp. nov., and Microvirga Alba sp. nov., Two New Species Isolated from Soil in South Korea
Authors: Oh Hyejin , Kim Myungkyum , Sriniva Sathiyaraj 
Published: June 2021

Abstract
Two novel Gram-stain-negative, aerobic, rod-shaped, circular, convex, light-pink and white-coloured bacterial strains BT291T and BT350T were isolated from soil collected in Uijeongbu city (37° 44′ 55″ N, 127° 2′ 20″ E) and Jeju island (33° 22′ 48″ N, 126° 31′ 48″ E), respectively, South Korea. Phylogenetic analysis based on 16S rRNA gene sequences revealed that strains BT291T and BT350T belong to a distinct lineage within the genus Microvirga (family Methylobacteriaceae, order Rhizobiales, class Alpha Proteobacteria, phylum Proteobacteria, kingdom Bacteria). The 16S rRNA gene sequence similarity between the two strains BT291T and BT350T was 97.4 %. The two strains were found to have the same quinone system, with Q-10 as the major respiratory quinone. The major polar lipids of strains BT291T and BT350T were phosphatidylethanolamine (PE), diphosphatydilglycerol (DPG), phosphatidylcholine (PC) and phosphatidylglycerol (PG). The major cellular fatty acids of strain BT291T were C18:1 ω7c (58.2 %) and cyclo-C19:0 ω8c (25.7 %). The major cellular fatty acids of strain BT350T were C18:1 ω7c (38.5 %) and cyclo-C19:0 ω8c (27.7 %). Based on the polyphasic analysis (phylogenetic, chemotaxonomic and biochemical), strains BT291T and BT350T can be suggested as two novel bacterial species within the genus Microvirga and the proposed names are Microvirga amygdalina and Microvirga alba, respectively. The type strain of Microvirga amygdalina is BT291T (= KCTC 72368T = NBRC 114845T) and the type strain of Microvirga alba is BT350T (= KCTC 72385T = NBRC 114848T).
Experimental and Theoretical Study on the Transformation Behavior of Bisphenol S by Radicals Driven Persulfate Oxidation
Authors: Wei Junyan , Yin Linning , Qu Ruijuan , Al-Basher Gadah , Pan Xiaoxue , Wang Zunyao 
Published: June 2021

Abstract
An in-depth study on the degradation of bisphenol S (BPS) by both single-walled carbon nanotubes and heat activated persulfate (PS) was investigated in detail. The factors like materials dosage, initial substrate concentration, initial pH and water matrix on removal of BPS were evaluated and 10 µM BPS could be completely removed in 90 min under the optimal conditions of [BPS]0: [PS]0 = 1: 100, T = 25 ℃, pH0 = 7.0, [N-SWCNTs] = 20 mg·L− 1. Fast removal of BPS was also obtained when reaction temperature reached 65 ℃ without catalyst. There were 15 intermediates identified in total; and hydroxylation, sulfate addition, carboxylation, the cleavage of S − C bond and polymerization were considered as the main transformation pathways of BPS in both two systems based on LC-MS analysis. The proportion discrepancy of •OH and SO4•− involved in two systems led to different distribution and abundance of observed products. The results of transition state calculation further confirmed the reaction potential of hydroxylation, hydrogen atom abstraction and sulfate addition, and the minimum reaction barriers were 22.20, 25.06 and 13.85 kJ/mol, respectively. The present work firstly reveals the overall transformation behavior of BPS in radicals-triggered PS system by combining experimental and theoretical study.
SARS-CoV-2 and Exposure to Pollution of the Population Near an Industrial Area in the Metropolitan Region in São Paulo State, Brazil
Authors: Zaccarelli-Marino Maria Angela , Balderi Thalles , Crepaldi Felipe , Alessi Rudá , Martins Marco 
Published: June 2021

Abstract
Industrial installations close to residential areas could cause health risks. Our objectives are to evaluate the interaction between pre-existing conditions (i.e., rhinitis, sinusitis, pharyngitis, obstructive pulmonary diseases (OPDs), conjunctivitis, dermatitis and primary hypothyroidism (PH)) and a higher risk of complications when infected with SARS-CoV-2 in residents exposed to long-term air pollutants. With a focus on the area affected by the Capuava Petrochemical Complex (CPC) (Region 1) and combining the AERMOD dispersion model with the Weather Research Forecast (WRF) (2016), we evaluated the Greater ABC region, Brazil. The concentrations of the nitrogen dioxide (NO2), carbon monoxide (CO), particulate matter (PM10), sulfur dioxide (SO2) and volatile organic compounds (VOCs) were analyzed in 2017 and these data were correlated with data obtained in a survey of 2004 residents 8–72 years of age of both sexes; 1002 (Region 1), and 1002 of them reside within the areas surrounding various industrial areas (Region 2). SARS-CoV-2 cases were collected from the Greater ABC region. Region 1 showed higher average concentrations of all pollutants analyzed. Among the 2004 total residents, there were significant differences between Region 1 and Region 2 in the incidence of cases of rhinitis, sinusitis, pharyngitis, OPDs, conjunctivitis, dermatitis and PH demonstrating that there is a higher incidence of the evaluated diseases in residents who live closer to the CPC. Compared with residents with these diseases, the residents of Region 1 had a higher relative risk of complications when infected with SARS-CoV-2 than did the residents of Region 2.
Highly Active Fenton-Like Catalyst Derived from Solid Waste-Iron Ore Tailings Using Wheat Straw Pyrolysis
Authors: Gao Lihui , Wang Lizhang , Li Shulei , Cao Yijun 
Published: June 2021

Abstract
The pollutants degradation rate of iron ore tailings-based heterogeneous catalysts is the main factor limiting its application. Herein, an iron ore tailings-based Fenton-like catalyst(I/W(3:1)-900-60) with relative fast catalysis rate was constructed by co-pyrolysis(900 ℃, 60min holding time) of iron ore tailings and wheat straw with mass ratio of 3:1. With wheat straw blending, the generated I/W(3:1)-900-60 presented a larger surface area(24.3 m2/g), smaller pore size(3.707 nm), reduced iron species (Fe2+ from magnetic) and a higher catalytic activity(0.0229 min-1) than I-900-60 (1.196 m2/g, 12.935 nm, 0.012 min-1) pyrolyzed using a single iron ore tailings under the same pyrolysis conditions. In addition, biochar and iron ore tailings in I/W(3:1)-900-60 were tightly combined through chemical bonding. The optimal catalyst remains active after three cycles, indicating its catalytic stability and recyclability. The good Fenton-like MB degradation efficiency of I/W(3:1)-900-60 was ascribed to the sacrificial role of biochar, as well as the electron transfer between biochar and iron active sites or the redox cycles of ≡Fe3+/Fe2+. This finding provides a facile construction strategy for a highly active iron ore tailings-based Fenton-like catalyst, and thereby had a great potential application in wastewater treatment.
E-Learning and the Virtual Transformation of Histopathology Teaching During COVID-19: Its Impact on Student Learning Experience and Outcome.
Authors: Waugh Samantha , Devin James , Lam Alfred , Gopalan Vinod 
Published: June 2021

Abstract
Background
This study evaluated the effectiveness of online histopathology teaching in medical education during the 2020 COVID-19 pandemic.
Methods
Second-year medical students (n = 150) who had previously completed one year of face-to-face histopathology teaching, completed an online questionnaire rating their learning experiences before and during the COVID-19 pandemic after the completion of their histology and pathology practical sessions. The students' histopathology assessment results were then compared to the histopathology results of a prior second-year cohort to determine if the switch to online histopathology teaching had an impact on students' learning outcome.
Results
A thematic analysis of the qualitative comments strongly indicated that online histopathology teaching was instrumental, more comfortable to engage in and better structured compared to face-to-face teaching. Compared to the previous year's practical assessment, the mean overall mark was significantly improved from 65.36% ± 13.12–75.83% ± 14.84% (p < 0.05) during the COVID-19 impacted online teaching period.
Conclusions
The transformation of teaching methods during the 2020 COVID-19 pandemic improved student engagement and positive learning outcomes in histology and pathology education.
First-Principles DFT Insights into the Mechanisms of CO2 Reduction to CO on Fe (100)-Ni Bimetals
Authors: Kwawu Caroline , Aniagyei Albert , Konadu Destiny , Menkah Elliot , Tia Richard 
Published: June 2021

Abstract
Iron and nickel are known active sites in the enzyme carbon monoxide dehydrogenases (CODH) which catalyzes CO2 to CO reversibly. The presence of nickel impurities in the earth abundant iron surface could provide a more efficient catalyst for CO2 degradation into CO, which is a feedstock for hydrocarbon fuel production. In the present study, we have employed spin-polarized dispersion-corrected density functional theory calculations within the generalized gradient approximation to elucidate the active sites on Fe (100)-Ni bimetals. We sort to ascertain the mechanism of CO2 dissociation to carbon monoxide on Ni deposited and alloyed surfaces at 0.25, 0.50 and 1 monolayer (ML) impurity concentrations. CO2 and (CO + O) bind exothermically i.e., -0.87 eV and − 1.51 eV respectively to the bare Fe (100) surface with a decomposition barrier of 0.53 eV. The presence of nickel generally lowers the amount of charge transferred to CO2 moiety. Generally, the binding strengths of CO2 were reduced on the modified surfaces and the extent of its activation was lowered. The barriers for CO2 dissociation increased mainly upon introduction of Ni impurities which is undesired. However, the 0.5 ML deposited (FeNi0.5(A)) surface is promising for CO2 decomposition, providing a lower energy barrier (of 0.32 eV) than the pristine Fe (100) surface. This active 1-dimensional defective FeNi0.5(A) surface provides a stepped surface and Ni-Ni bridge binding site for CO2 on Fe (100). Ni-Ni bridge site on Fe (100) is more effective for both CO2 binding or sequestration and dissociation compared to the stepped surface providing the Fe-Ni bridge binding site.
Determining the Unsaturated Hydraulic Conductivity of Remoulded Loess with Filter Paper Method and Soil Column Seepage Test
Authors: Chen Wenwu , Jia Quanquan , Liu Peng , Tong Yanmei 
Published: June 2021

Abstract
Loess is very widely distributed, and the unsaturated hydraulic conductivity of loess is related to many engineering issues. In order to determine the unsaturated hydraulic conductivity of remolded loess more conveniently and at a lower cost, filter paper test and soil column seepage test were carried out. The results indicate that in the one-dimensional soil column seepage process, the unsaturated hydraulic conductivity of loess increases with the increase of the volumetric water content, and as the seepage time continues, the unsaturated hydraulic conductivity of loess at different depths gradually becomes uniform. The changes in the microstructure indicate that the collapsible settlement will occur during the seepage process, which will reduce the unsaturated hydraulic conductivity of the underlying loess to a certain extent. Compared with the experimental results, the soil hydraulic conductivity curve (SHCC) obtained by the van Genuchten-Mualem model (VG-M model) underestimates the magnitude of unsaturated hydraulic conductivity in the part with a low volumetric water content (< 20%). and the Childs ༆ Collis-George model (CCG model) has more consistent results with the experimental results because it is based on more segments of the soil-water characteristic curve (SWCC).
Evaluation of Carcass Characteristics and Egg Quality Traits of Kuroiler and Sasso Chickens Reared Under On-Station and On-Farm Management Conditions in Tanzania
Authors: Guni Fadhili Said , Mbaga S. H. , Katule A. M. , Goromela E. H. 
Published: June 2021

Abstract
Two studies were conducted to evaluate the carcass characteristics and egg quality traits of Sasso and Kuroiler chickens under on-farm and on-station management conditions. Carcass characteristics were evaluated under on-station only while egg quality was evaluated under both management conditions. A total of 240 hens and 240 cocks were raised under on-station condition and evaluated for egg and carcass quality respectively. Meanwhile, 320 hens were raised under on-farm condition and evaluated for egg quality only. At the end of each of the 16th and 20th weeks of age, a sample of 10 cocks per breed was randomly selected and sacrificed for carcass traits evaluation. To study egg quality, a total of 666 fresh eggs (246 eggs from on-farm and 420 eggs from on-station) were used to evaluate the external and internal egg quality traits. The recorded data were analyzed using the General Linear Models (GLM) procedure of SAS software ( SAS 2009). The results show that except for shell, yolk and albumen ratios, the mean values of other egg quality traits studied were higher for on-station than on-farm. Kuroiler chickens had higher values for egg weight, egg length, yolk weight, albumen height and Haugh unit than Sasso chickens. Live weight, carcass weight and carcass parts weight were found to be higher for Sasso than for Kuroiler at both ages of slaughter. It is concluded that there are variations between managements and breeds on egg quality traits. Carcass characteristics are affected by both breed and slaughter age.
Color Removal from Wastewater using a Synthetic High Performance Antifouling GO-CPTMS@Pd-TKHPP/Polyether Sulfone Nanofiltration Membrane
Authors: gholami foad , zinadini sirus , Kamrani Soheila Nakhjiri , zinatizadeh ali akbar , Bahrami Kiumars 
Published: June 2021

Abstract
Modified graphene oxide with 5,10,15,20-tetrakis‐(4‐hexyloxyphenyl) ‐porphyrin and palladium (II) (signified by GO-CPTMS@Pd-TKHPP) prepared as a novel antifouling polyether sulfone (PES) blended nanofiller membrane. The membrane efficiency has been analyzed such as pure water flux (PWF), hydrophilicity and antifouling features. By increasing of modified graphene oxide percentage from 0 to 0.1 wt.% in polymer matrix the PWF was incremented from 14.35 to 37.33 kg/m2.h at 4bar. The membrane flux recovery ratio (FRR) has been investigated by applying powdered milk solution, the FRR results indicated that the 0.1 wt.% modified graphene oxide membrane showed the positive effect on fouling behavior with Rir and FRR value 8.24 and 91.73% respectively. The nanofiltration membrane performance was assessed applying the Direct Red 16 dye rejection. It was demonstrated that the optimal membranes (0.1 wt.% modified graphene oxide) had notable dye removal (99.58 % rejection). The results are also verified by measuring the scanning electron microscopy (SEM), water contact angle (WCA) and atomic microscopy analysis (AFM).
Evolutionary Discovery of Natural-Language Coreference Chains for Social Media Analysis
Authors: Atkinson John , Escudero Alex 
Published: June 2021

Abstract
Communicating messages on social media usually conveys much implicit linguistic knowledge, which makes it difficult to process texts for further analysis. One of the major problems, the linguistic co-referencing task, has mostly been addressed for formal and full-sized text in which a relatively clear discourse structure can be discovered, using Natural-Language Processing techniques. However, texts in social media are short, informal and lack a lot of underlying linguistic information to make decisions so traditional methods can not be applied. Furthermore, this may significantly impact the performance of several tasks on social media applications such as opinion mining, network analysis, sentiment analysis, text categorization.In order to deal with these issues, this research address the task of linguistic co-referencing using an evolutionary computation approach. It combines discourse coreference analysis techniques, domain-based heuristics (i.e., syntactic, semantic and world knowledge), graph representation methods, and evolutionary computation algorithms to resolving implicit co-referencing within informal opinion texts.Experiments were conducted to assess the ability of the model to find implicit referents on informal messages, showing the promise of our approach when compared to related methods.
The Long-term Effectiveness of a Community-based Lifestyle Intervention on Tobacco-related Habits in Adolescent Boys and Girls: Tehran Lipid and Glucose Study
Authors: Masihay-Akbar Hasti , Amiri Parisa , Rezaei Marjan , Jalali-Farahani Sara , Cheraghi Leila , Momenan Amir Abbas , Azizi Fereidoun 
Published: June 2021

Abstract
Background: To assess the long-term effectiveness of a community-based intervention on cigarette, passive, and hookah smoking in adolescent boys and girls. Methods: 1159 adolescents who participated in the Tehran Lipid and Glucose Study (TLGS) between 2001 and 2004 were followed for 12 years (every-three-year follow-ups). Participants in the intervention area received lifestyle interventions in the settings of family, schools, and community. After excluding those with missing baseline parental data (n=66), complete parental data of 1093 adolescents was used for cluster analysis, and families were classified as low- and high-risk. Afterward, 296 individuals who did not complete intervention/follow-ups were excluded. The GEE analysis was performed on 797 adolescents (369 boys) to assess the intervention effect on tobacco-related habits; 605 and 192 resided in the control and intervention area, respectively.Results: Mean age of adolescents was 15.21±1.95 years at baseline. Adolescents living in high-risk families were more at risk of cigarette, passive, and hookah smoking. The intervention decreased the odds of cigarette and passive smoking by 38% and 57%, respectively. The intervention was not successful in reducing the risk of hookah smoking in adolescents. After sex-specific analysis, the intervention reduced the risk of current cigarette smoking by 40% only in boys and passive smoking in both sexes.Conclusions: Targeting lifestyle behaviors in adolescents and their families in a community setting reduces cigarette smoking in school-aged boys and protects both sexes from secondhand smoke; findings that could be valuable for designing future health promotion interventions focusing on adolescents smoking.Trial registration: This study is registered at Iran Registry for Clinical Trials (IRCT), a WHO primary registry (http://irct.ir). The registry date is 29/10/2008; (IRCTID: IRCT138705301058N1).
Failure Prediction of Open-pit Mine Landslide Containing Complex Geological Structure using Inverse Velocity Method: A Case Study in West Open-Pit mine, Pingzhuang, China
Authors: Du Han , Song Danqing 
Published: June 2021

Abstract
In the field of open-pit geological risk management, landslide failure time prediction is one of the important topics. Based on the analysis of displacement monitoring data, the inverse velocity method (IVM) has become an effective method to solve this issue. In order to improve the reliability of landslide prediction, four filters were used to test the velocity time series, and the effect of landslide failure time prediction was compared and analyzed. The IVM is used to predict the failure time of open-pit coal mine landslide. The results show that the sliding process of landslide can be divided into three stages based on the IVM: the initial attenuation stage (regressive stage), the second attenuation stage (progressive stage), the linear reduction stage (autoregressive stage). The accuracy of the IVM is closely related to the measured noise of the monitoring equipment and the natural noise of the environment, which will affect the identification of different deformation stages. Compared with the raw data and the exponential smoothing filter (ESF) models, the fitting effect of short-term smoothing filter (SSF) and long-term smoothing filter (LSF) in the linear autoregressive stage is better. A slope displacement pixel difference method based on fitting accuracy and field monitoring signals is proposed to determine the point onset-of-acceleration (OOA) that is very important role for landslide prediction. A stratified prediction method combining SSF and LSF is proposed. The prediction method is divided into two levels, and the application of this method is given.