bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Potension of Aditory Nerve Damage on Milling Industry Workers in Jember Regency
Authors: Firdaus Jauhar 
Published: March 2021

Jember Regency is one of the agro-industrial areas in Indonesia with a variety of activities that can produce noise including milling industry. Exposure to noise that is too strong or too long will damage the auditory nerve. The type of material being grounded determines the amount of noise produced so that the potential for hearing nerve damage also varies. This study aims to determine the level of noise produced by the milling industry and analyze the potential for hearing nerve damage in milling workers in Jember Regency. This type of research is observational analytic with cross-sectional approach. This research was conducted by measuring noise in several grinding locations in Jember that were randomly determined. Types of careful milling is grinding meat, coffee, rice, sticky rice and coconut. In addition to measuring the noise level, a short interview was also conducted with the mill workers regarding how long they worked at the mill every day. The measurement results are then analyzed descriptively and compared with standards set by the government and the Occupational Safety and Health Administration (OSHA). In this study it was found that the grinding of meat raw materials produced an average noise level of 88.5 db, coffee of 88.5 db, rice of 88.9 db, sticky rice of 87.3 db and coconut of 80.7 db. The duration of exposure to noise in milling meat, coffee, rice and sticky rice ranges from 9-12 hours a day. While the duration of noise exposure to coconut milling workers ranged from 6-9 hours. Therefore it can be concluded that milling meat, coffee, rice and sticky rice has the potential to cause hearing loss for workers.
Keywords: agroindustry, hearing loss, noisy, milling
Effect of Cigarette Smoke Exposure Status on Pregnant Women as Passive Smokers with Birth Weight in Arjasa Health Center, Jember Regency
Authors: Damarawati Anis Talitha , Rachmawati Dwita Aryadina , Hairrudin Hairrudin 
Published: March 2021

In Indonesia, there are around 65.6 million women and 43 million children exposed to cigarette smoke and thus act as passive smokers. If pregnant women act as passive smokers, then it can increase the risk of pregnancy complications, including LBW. Babies with LBW are one of the public health problems that must be considered because LBW is a major predictor of infant mortality, especially in the first month of life. The purpose of this study was to determine the effect of exposure to cigarette smoke on pregnant women as passive smokers on the incidence of LBW in Arjasa Health Center, Jember Regency. This type of research uses an observational analytic method with a retrospective case control study design. The sample of this study amounted to 60 people. The bivariate analysis using the chi square test stated that there was a significant relationship between exposure to 2x3 cigarette smoke (p = 0.031), exposure to 2x2 cigarette smoke (p = 0.030; OR = 4) and age of pregnant women (p = 0.033; OR = 5.2) with birth weight at Arjasa Community Health Center, Jember Regency. While the results of bivariate analysis using the chi square test stated that there was no significant relationship between jobs (p = 0.422; OR = 1.78), history of parity (0.784; OR = 1.3), and ANC frequency (p = 1,000; OR = 1.17). the results of multiple logistic regression analysis revealed that there was a significant effect between exposure to cigarette smoke (p = 0.050; OR = 3.39) and age (p = 0.037; OR = 4.6) on birth weight at Arjasa Health Center, Jember Regency. The conclusion of this study is that exposure to cigarette smoke has a significant relationship with birth weight and age is the most influential risk factor for birth weight in Arjasa Health Center, Jember Regency.
Keywords: Birth weight, LBW, cigarette smoke exposure
The Antibacterial Effect of Ethanol Edamame Seeds (Glycine Max (L) Merril) Extract to E.coli Bacteria
Authors: Akhita Diayu Putri , Junaidi Edy , Wahyudi Septa Surya 
Published: March 2021

Abstract
Infectious diseases can occur in all parts of the body. One of the causes infection in humans is Eschericiae coli bacteria. Eschericiae coli is a rod-shaped bacteria, a gram negative bacteria, facultative aerobics and classified family member of Enterobacteriaceae from the Gammaproteobacteria class. Along the times, E.coli bacteria have resistent to some antibiotics. So we need a new alternative. There is a antibacterial substance in the isoflavon group contained in edamame. Genistein is a main isoflavon in edamame that have antiinflammation, antibacterial, and antioxidant effects. The purpose of this study was to determine is there any antibacterial effects in ethanol edamame seeds extract to E.coli bacteria. This study used a true experimental research design in vitro with a post test only control group design. The average diameter results of the inhibition zone were analyzed using the Kruskal-Wallis method and obtained p = 0.001 which means there are significant differences in at least two groups. After that, the Mann Whitney post hoc test was conducted and a significant difference was found in the positive and negative control groups for all groups but there was no difference in the treatment group, both groups K1, K2 and K3 for all groups.
Keywords : Edamame, Antibacterial, E.coli
DNA Quality and Quantity on Blood Spot Post Soil and Ultraviolet-C Exposure
Authors: Jauhani Muhammad Afiful , Rachmania Sheilla 
Published: March 2021

Bercak darah dapat ditemukan di tempat kejadian perkara (TKP) pada banyak kasus tindak kekerasan. Asam deoksiribonukleat (DNA) pada darah dapat digunakan sebagai data primer untuk proses identifikasi akan tetapi bercak darah di TKP berisiko rusak akibat pajanan tanah dan ultraviolet. Tujuan utama dari penelitian ini adalah untuk mempelajari efek kombinasi dari pajanan sinar ultraviolet-C dan tanah terhadap kualitas dan kuantitas DNA pada bercak darah. Sebanyak 20 gelas berisi 200 gram tanah ditetesi 900µl darah dan diberikan pajanan sinar ultraviolet-C dalam tiga kelompok berdasarkan durasi pajanan yakni satu hari, tiga hari, dan lima hari. Satu kelompok digunakan sebagai kontrol. Ekstraksi DNA dilakukan menggunakan DNAZol dilanjutkan dengan pengukuran spektrofotometri untuk mengetahui kualitas dan kuantitas DNA. Peningkatan konsentrasi DNA dapat diamati yaitu 681,1 pada hari pertama menjadi 1274,7 pada hari ketiga dan mulai menurun menjadi 1090,6 pada hari kelima, sedangkan kemurnian DNA terus menurun secara konstan seiring dengan meningkatnya durasi pajanan. Penelitian ini menunjukkan bahwa pajanan sinar ultraviolet-C dan tanah menyebabkan degradasi molekul DNA menjadi fragmen-fragmen molekul yang lebih kecil sehingga terjadi peningkatan kuantitas DNA yang disertai penurunan kualitas DNA. Penurunan kualitas DNA dapat mempersulit proses identifikasi sehingga isolasi DNA sampel pada tanah terbuka yang terpajan matahari harus dilakukan sesegera mungkin.

Kata Kunci: DNA, darah, tanah, ultraviolet C, patologi forensik
The Correlation between Knowledge Level and Personal Hygiene with Scabies Occurrence in Miftahul Ulum Islamic Boarding Schools Jember Regency
Authors: Nandira Anthia Ayu , Armiyanti Yunita , Riyanti Rini 
Published: March 2021

Scabies is caused by infestation and sensitization of Sarcoptes scabiei hominis varieties. Scabies is easily transmitted to individuals who live in groups such as boarding schools. Knowledge of scabies that is lacking and low in individual hygiene among student causes a transmission to be faster and wider. The purpose of this study was to determine the relationship between the characteristics, level of knowledge and individual hygiene of the student with the occurrence of scabies at the Miftahul Ulum Islamic Boarding School in Kalisat District, Jember Regency. This study used an observational analytical method with cross-sectional. Of the population of 358 students, 229 students were willing to become respondents. The results showed that 105 students (45.9%) suffered from scabies. The chi-square test results showed the characteristics of respondents such as gender, pruritus complaints, pruritus onset when entering the hut, treatment history was associated with the incidence of scabies (p <0.05). Risk factors for individual hygiene in the form of using towels alternately and washing towels together were also associated with the incidence of scabies (p <0.05). Bivariate analysis at the level of individual knowledge and hygiene as a whole showed no significant association with the incidence of scabies (p> 0.05). The result of multiple logistic regression test showed 2 variables, namely, sex and pruritus onset when entering the lodge significantly associated with the incidence of scabies (p <0.05).
Keywords : scabies, knowledge level, personal hygiene
Relationship of Cholinesterase Activity with Blood Glucose Levels Due to Pesticide Exposure to Farmers in Mlokorejo Village
Authors: Luqmani Muhammad Ryznar Faisal Nur , Sofiana Kristianningrum Dian , Hermansyah Bagus 
Published: March 2021

Increase in blood glucose levels can be caused by the long-term use of pesticides by farmers. This study aims to determine whether there is a correlation between the activity of cholinesterase as an indicator of exposure to pesticides and blood glucose of farmers in Mlokorejo Village, Jember Regency. The research method is observational-analytic with a cross-sectional study design. Data in the form of general characteristics of the sample were obtained through interviews, while the data of the activity of cholinesterase and blood glucose levels of farmers were obtained at the Biochemical Laboratory of the Faculty of Medicine, Jember University. The sample size of this study is 30 samples. All of the samples are having an increased activity of cholinesterase. Most of the samples are having normal blood glucose levels. Based on the results of statistical analysis using the Spearman correlation test (a= 0.05), it was concluded that there was no significant correlation between the two variables (p = 0,191).
Keywords: blood glucose, cholinesterase, pesticides
The Effect of Coping on Family Health in Dealing with COVID-19 Pandemic
Authors: Mashudi Sugeng , Susanti Sri , Andarmoyo Sulistyo , Yulidaningsih Elok , Binti Mohd Yusop Yuzana 
Published: March 2021

The emergence of the COVID 19 pandemic is perceived as an unprecedented pressure. If the pandemic is prolonged, it will be able to reduce family health. This study provides an analysis of the effect of coping on family health in dealing with COVID 19. Researchers use the family health theory approach to answer the research objectives. Using a sampling quota, an online survey of 90 respondents throughout Indonesia. The results showed that 15% of family health is determined by the family's coping during the face of the COVID 19 pandemic. It is necessary to apply various coping strategies to support optimal family health.
Keywords: COVID 19, coping, family health, pressure.
SIFAT-SIFAT MARSHALL DAN RESILIENT MODULUS PADA CAMPURAN LAPIS TIPIS DENGAN PENGGUNAAN POLYMER MODIFIED BITUMEN E60
Authors: Maenkar Verry , Setyawan Ary , Suryoto Suryoto 
Published: March 2021

<p>Lapis tipis campuran aspal panas (<em>Thin Surfacing Hot Mix Asphalt</em>) merupakan salah satu alternatif yang dapat mengantisipasi masalah ketebalan perkerasan jalan, salah satu teknologi yang sedang dikembangkan sebagai usaha ramah lingkungan untuk perkerasan jalan, namun penggunaan lapis tipis aspal dianggap masih belum maksimal dengan beberapa kelemahan yang masih terdapat pada lapisan ini. Penggunaan lapis tipis aspal, daya lekat aspal yang semakin sedikit juga harus dipertimbangkan. Salah satu cara untuk memperbaiki kualitas aspal adalah dengan menggunakan bahan modifikasi yang telah tersedia di pasaran. Suatu bahan baru yang tersedia di pasaran adalah <em>Starbit E-60</em>. <em>Starbit E-60</em> adalah sebuah produk aspal <em>Polymer Modified Bitumen </em>yang di formulasikan untuk memenuhi kebutuhan perkembangan kebutuhan transportasi. Jadi perlu adakan penelitian tentang berapa kadar aspal optimum lapis tipis aspal panas dan sifat karakteristik aspal dengan menggunakan <em>starbit E-60</em> dan aspal penetrasi 60/70 optimum pada campuran aspal dengan metode <em>Marshall</em>. Dengan metode eksperimental menggunakan metode <em>Marshall </em>dapat ditentukan nilai stabilitas, kelelahan plastis (<em>flow</em>), berat volume (<em>density</em>), persen rongga, <em>Marshall Quotient</em> (MQ) pada campuran lapis tipis denwtgan <em>starbit E-60</em> dan aspal penetrasi 60/70, selanjutnya dapat digunakan untuk menentukan kadar aspal optimum, serta mengetahui sifat karakteristik <em>marshall</em>. Hasil test <em>Marshall</em> dari lapis tipis campuran aspal panas didapatkan kadar <em>starbit</em> optimum sebesar 5,53%, dengan menggunakan gradasi yang sama didapatkan kadar aspal optimum aspal penetrasi 60/70 sebesar 5,84%. Pada uji ITSM campuran aspal <em>starbit E-60 </em> mendapatkan nilai resilient modulus sebesar 5060,05 Mpa pada suhu 20<sup>0C</sup> dan 2479,78 Mpa pada suhu 40<sup>0</sup>C, sedangkan campuran aspal Penetrasi 60/70 mendapatkan nilai resilient modulus sebesar 4667,32 Mpa pada suhu 20<sup>0</sup>C dan 1502,78 Mpa pada suhu 40<sup>0</sup>C.</p>
A New Edition of Contarini’s De Immortalitate Animae
Authors: Burzelli Luca 
Published: March 2021

Review article of:
Gasparo Contarini, De immortalitate animae / On the Immortality of the Soul, edited by Paul Richard Blum in cooperation with Elisabeth Blum, Jan Čížek, Martin Holan, Jan Janoušek, Jozef Matula, Jiří Michalík, Tomáš Nejeschleba, Lloyd A. Newton, Jana Slezáková, Martin Žemla, Verlag Traugott Bautz, Nordhausen 2020 (Studia Classica et Medievalia 26), 271 pp.
Uncovering Moses ben Sabbatai: A Fourteenth-Century Critic of Philosophers and Kabbalists
Authors: De Doncker Ellen 
Published: March 2021

Review article of:
Jean-Pierre Rothschild, Moise b. Sabbatai, lecteur juif du Livre des causes et adversaire de la Kabbale, en Italie, vers 1340, Turnhout, Brepols 2018 (Philosophy in the Abrahamic Traditions of the Middle Ages, 2).
Trauma and Pregnancy: Is Flow Cytometry Detection and Quantification of Fetal Red Blood Cells Useful? A Retrospective Cohort Study.
Authors: Rottenstreich Misgav , Meir Reut , Glick Itamar , Alexandrony Heli , Schwarz Alon D , Broide Ellen , Grisaru-Granovsky Sorina , Sela Hen Y 
Published: March 2021

Abstract
Purpose: To assess whether positive flow cytometry quantification of fetal red blood cells is associated with adverse outcomes in cases of trauma during pregnancy.Methods: A retrospective cohort study, at a single tertiary center between 2013 and 2019. All pregnant women with viable gestation involved in trauma who underwent flow cytometry were included. Flow cytometry was considered positive (≥0.03/≥30 ml). Composite adverse maternal and neonatal outcomes were compared between cases with positive and negative flow cytometry test. Univariate and multivariate logistic regression analysis were performed to assess the role of flow cytometry in predicting adverse outcomes. Adjusted odds ratios (aORs) and 95% confidence intervals (CIs) were calculated.Results: During the study 1023 women met inclusion and exclusion criteria. The mechanisms of injury were motor vehicle accident in 387 women (38%), falls in 367 (36%), direct abdominal trauma in 353 (35%) and in 14 women (1%) other mechanism of injury. Among the cohort, 119 women (11.6%) had positive flow cytometry (≥0.03/≥30 ml) with median result of 0.03 [0.03-0.04], while 904 women (88.4%) had negative flow cytometry test result (≤0.03/≤30 ml) with median result of 0.01 [0.01-0.02]. Composite adverse outcome occurred in 8% of the women, with no difference in the groups with vs. without positive flow cytometry (4.2% vs. 8.5%; p=0.1). Positive flow cytometry was not associated with any adverse maternal or neonatal outcome. This was confirmed on a multivariate analysis. Conclusions: Flow cytometry result is not related to adverse maternal and fetal/neonatal outcome of women involved in minor trauma during pregnancy. We suggest that flow cytometry should not be routinely assessed in pregnant women involved in minor trauma.
Pitfalls in Retinopathy of Prematurity Screening: A Qualitative Content Analysis
Authors: Albathi lojain , Abouammoh Nourah , Alsowaina Naif , Albalawi Hani , Alqahtani Abdullah , Talea Mohammed , Alsulaiman Sulaiman , Abouammoh Marwan A. 
Published: March 2021

Abstract
Purpose: To identify the pitfalls in retinopathy of prematurity (ROP) screening leading to advanced disease at Ministry of Health (MOH) hospitals in Saudi Arabia. Methods: A qualitative deductive content analysis was used to study the phenomena of defects in ROP screening. A retrospective review of medical records of newborns presenting to two tertiary eye care centers with advanced ROP (Stage 4 and 5) from January 2012 to June 2019 was completed. An extensive review of the original files at the referring hospitals was conducted, including the general condition and findings of ophthalmic examination and the sequence of follow-up until the infant was discharged/referred. Data analysis was completed using pre-structured categorization matrix. Results: Records of 29 infants with advanced stage ROP were identified. Only 13 medical records were available and obtained. The pitfalls in screening found in the study were failure to refer by the neonatologist, delayed follow-up by the ophthalmologist, failure to follow-up by the ophthalmologist, failure to diagnose by the ophthalmologist, poor documentation in patient files, unavailability of ophthalmologist, family negligence, lack of treatment and delayed referral to a higher center, and progression despite timely screening and management.Conclusion: Although clear ROP screening guidelines are available, implementations of these guidelines are suboptimal. This study showed the most common defect in screening is physician’s inadequacy and unavailability. A proper network of competent ROP screening physicians in all neonatal intensive care units should be established. Centers for advanced ROP surgery should be allocated to deliver a timely surgical care if needed.
A case report of a severe neonatal systemic vasculitis on the first day of life
Authors: Wong Stephanie , Demirkaya Erkan , Berard Roberta 
Published: March 2021

Abstract
BACKGROUND: Transmission of autoantibodies across the placenta has been associated with neonatal cutaneous vasculitis and lupus syndromes. Here we report a novel association of a case of new-onset maternal seronegative inflammatory arthritis associated with a transient systemic vasculitis in a neonate. CASE PRESENTATION: In the first 24 hours of life, a preterm baby boy was noted to have blue discoloration to all four extremities. A workup for sepsis and thrombosis were negative. Despite antibiotics, fresh frozen plasma and anticoagulation, the discoloration remained, particularly in the left index finger. This was associated with fever and a maximum C-reactive protein (CRP) of 148 mg/L. Two doses of intravenous immunoglobulin (IVIG) were given with short-term improvement. Echocardiogram was normal. The fever, elevated CRP and finger discoloration responded to high dose steroid administration. MRI angiography (MRA) of body and heart showed tortuosity of arteries in the upper and lower extremities with gadolinium uptake, suggestive of vasculitis. Autoantibody profile negative. Genetic panel for hereditary autoinflammatory diseases was negative as was as whole exome sequencing performed on the trio. The baby was weaned off steroids by 5 months of age. A small distal autoamputation of the left index finger occurred. He was born to a 28-year-old woman who developed new onset severe symmetrical polyarthritis at 8 weeks gestation. It was presumed this was reactive arthritis secondary to a dental infection. Infectious work up and autoantibodies were negative. She was treated with high dose prednisone for the remainder of her pregnancy. The mother was weaned off prednisone and treated with hydroxychloroquine for 8 months post-partum and remains in remission. A repeat MRA done at 1 year old showed mild residual tortuosities of the arteries in the forearms. The remainder of the medium and large vessels were within normal limits with no gadolinium enhancement to suggest active disease. The child is now 4 years old with normal growth and development. CONCLUSION: This is a unique case of new-onset seronegative presumed reactive arthritis in a mother with the rare development of a successfully treated medium vessel vasculitis in an infant.
GIS-Based Risk Mapping of Cutaneous Leishmaniasis: A Survey in an Endemic Area of Central Iran
Authors: Maracy Mohammad , Jaffary Fariba , Ebrahimi Afshin , Sokhanvari Fatemeh , Heidari Asieh , Koupaiee Hanieh Sharifian , Fadaei Reza , Ramazanpour Javad , Moazeni Malihe 
Published: March 2021

Abstract
Introduction: [Cutaneous Leishmaniasis (CL)] is Vector-borne infectious disease that is affected by various environmental agents. The main objective of this study was to determine the spatial distribution of CL incidence by using [Geographical Information System (GIS)].Materials and Methods: This is a cross-sectional study that was conducted during 5 years from 2014 to 2018 in Isfahan, Iran. We used the required data on each leishmaniasis patient that were recorded from 44 counties of Isfahan in databases and archive of provincial Health Centre. We used GIS for determining the incidence of CL in the high-risk foci. Moran index was used to identify high risk points (clustering in similar values) compared to the values of neighborhood points. Hot spot analysis was conducted by Getis-Ord-Gi. Results: The highest incidence of the disease occurred in the age group of 18-64 years and 61.6% of patients were male. According to seasonal distribution, autumn (58.6%) had the highest frequency. Time-trend of incidence showed that it had both decreasing and increasing, and there was a sudden upward trend of disease in 2018 except only two counties. The hot spots were involved the central areas of the Isfahan province slightly toward to the north and southeast of the province. Moran index showed that the differences for all points were not significant (p-value>0.05).Conclusions: Varzaneh (placed in southeast of Isfahan) was the hottest spot and had the worst position for leishmaniasis compared to all years and all cities.
Impact of cognitive reserve on dance intervention-induced changes in brain plasticity
Authors: Mitterová Kristína , Klobušiaková Patrícia , Minsterová Alžběta Šejnoha , Kropáčova Sylvie , Balážova Zuzana , Točík Jaroslav , Vaculíková Pavlína , Skotáková Alena , Grmela Roman , Rektorová Irena 
Published: March 2021

Abstract
Dance is a complex sensorimotor activity with positive effects on physical fitness, cognition, and brain plasticity in the aging population. We explored whether individual levels of cognitive reserve (CR) proxied by education moderate dance intervention (DI)-induced plasticity assessed by resting-state functional connectivity (rs-FC) changes of the sensorimotor network (SMN), and between the dorsal attention network (DAN) and anterior default mode network (aDMN). Our cohort consisted of 99 subjects, randomly assigned to either a DI group who underwent a 6-month intervention (n = 49, Mage = 69.02 ± 5.40) or a control group (n = 50, Mage = 69.37 ± 6.10). Moderation analyses revealed that CR moderated DI-induced increases of the SMN rs-FC with significant changes observed in participants with ≥ 13 years of education (b = .05, t(64) = 3.20, p < .001). Only DI alone was a significant predictor of the DAN-aDMN crosstalk change (b = .06, t(64) = 2.16, p = .03). The rs-FC increases in the SMN were correlated with an improved physical fitness measure, and changes in the DAN-aDMN connectivity were linked to better performance on a cognitive task. Consistent with the passive CR hypothesis, we observed that CR correlated only with baseline behavioral scores, not their change.