bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of the Cavus and Planus Foot on Biomechanics Aspect of the Plantar Pressure in Adolescents With Idiopathic Scoliosis
Authors: Barsotti Carlos Eduardo Gonçalves , Tostes Gustavo Alves , Andrande Rodrigo Mantelatto , Schmidt Ariane Verttú , Torini Alexandre Penna , Ribeiro Ana Paula 
Published: February 2021

Abstract
Purpose: To verify the effect of cavus and planus feet on plantar pressure during static posture in adolescents with idiopathic scoliosis (AIS). Methods: Cross-sectional study. Sixty adolescents with idiopathic scoliosis (AIS) were evaluated and divided into three groups: normal foot (n=20), cavus foot (n=20), and planus foot (n=20). The scoliosis was confirmed by a spine X-ray exam (Cobb angle). The plantar arch index (AI) was calculated from the ratio between the midfoot area and the total area of the foot. Distribution plantar pressure data was collected using a plantar pressure system. The contact area, maximum force, and peak pressure were acquired over areas: forefoot, midfoot, and lateral and medial rearfoot. Results: The Cobb angle of the AIS of the major curves averaged 33.7°±10.7°, the mean TK was 32.6°±6.7°, and the mean LL was 31.4°±8.3°. AIS with cavus feet showed a reduction in contact area and peak pressure on the midfoot and lateral rearfoot when compared to planus and normal feet, as well as maximum force on the midfoot and rearfoot (medial and lateral). Planus feet showed increased peak pressure and maximum force on the midfoot when compared to cavus and normal feet. Another observation was that planus feet also promoted an increase in peak pressure and maximum force on rearfoot in relation to cavus feet. Conclusions: Foot posture influences plantar pressure of patients with AIS. Cavus feet decrease the plantar load on the midfoot and rearfoot while planus feet increased plantar pressure in these regions. Level of evidence: III
Diverse Biotransformation of Sulfur in Antarctic Lake Sediments
Authors: Shen Lili , Huang Tao , Chen Yuanqing , Chu Zhuding , Xie Zhouqing 
Published: February 2021

Abstract
Microbial communities, sulfur isotope of sulfides (δ34SAVS and δ34SCRS) and sulfur and oxygen isotopes of sulfate (δ34SSO4 and δ18OSO4) in sediments were analyzed to study the biotransformation of sulfur in a penguin-affected lake Y2 and a pristine YO from Fildes Peninsula, Antarctic Peninsula. The microbial communities in Y2 were mainly associated with penguin activities, while those in YO were limited by nutrients. The much enriched δ34SSO4 recorded at depth of 30, 41 and 52 cm in Y2 indicates very strong sulfate reduction therein. The sulfur-degrading bacteria Pseudomonas in 0–23 cm of Y2 was 3.5 times as abundant as that of sulfur oxidizing bacteria (SOB), indicating remarkable remineralization of organic sulfur. While abundant SOB and 34S-depleted sulfate indicate considerable sulfur oxidation in 34–56 cm layer in Y2. In YO sediments, the highest abundance of Desulfotalea and the most enriched δ34SSO4 (35.2‰) and δ34SCRS (2.5‰) indicate strongest sulfate reduction in 28 cm layer. High abundance of Pseudomonas indicates active remineralization of organic sulfur in 3–5 cm layer in YO. While the medium δ34SSO4 and considerable abundance of SOB and SRB indicate concurrence of sulfur oxidation and sulfate reduction in other layers in YO. Our results show that high level of organic matter inputs from penguin populations support the diverse microbial community and biotransformation of sulfur in freshwater ecosystems in Antarctica.
Integrating a Clinical Pharmacist into a Multidisciplinary Pain Center: Feedback and Perspectives
Authors: BOURSIER Amélie , Ferret Laurie , Fulcrand Julie , Heiremans Julie Delvoye - , Charpentier Pascal , Dujardin Laure , Lemaire Antoine 
Published: February 2021

Abstract
Background:In January 2017, two clinical pharmacists joined our institution’s multidisciplinary pain center care team. They help optimize management of chronic pain patients. The purpose of this study is to present and discuss an innovative model of clinical pharmacy development in France.Method:A retrospective study for the period January 1, 2017 to June 30, 2019 was conducted.The care team evaluated the clinical pharmacy service using a satisfaction questionnaire.The outcome measures were the type of activities, number of interventions and healthcare team satisfaction.Results:During this period, the clinical pharmacists intervened 1839 times. Conventional clinical pharmacy activities do not represent the majority of solicitations, which shows the advantage of both adapting the activities deployed to the expectations of care teams and expanding care packages to those needs.Pharmaceutical advice was the main activity, mostly given to physicians (55%) and patients (35%).They consisted in contributing to the choice of drug strategy, explaining the treatment, adjusting a dosage, and improving relations between hospital and community caregivers.The feedback forms showed that caregivers believe that clinical pharmacy has positive impacts on patient care and healthcare team quality of life. Conclusion:The numerous requests for clinical pharmacist interventions show the care team’s significant interest in this new activity. Clinical pharmacy has shown its added value in patient quality of care and helps optimize the patient's care pathway by decompartmentalizing hospital and community medicine.This clinical pharmacy development model is innovative in France, as pharmacists are full members of the care team. Specific activities were set up progressively according to the care team’s needs. Caregivers’ expectations and requests made in clinical pharmacy progressed over time to more specialized activities. Assessment of team satisfaction showed that this model was very well accepted by caregivers and highlights the relevance of adapting and specializing clinical pharmacy development to the care team’s needs.
Living Particulate Fluxes in Throughfall and Stemflow During a Pollen Event
Authors: Guidone Michele , Gordan D. Alex R. , Stan John Toland Van 
Published: February 2021

Abstract
Pollen shedding can produce rapid, abundant exchanges of nutrient-rich biomass 9 from plant canopies to the surface. When pollen deposits onto understory plants, it can be 10 washed off during storms via throughfall (a drip flux) and stemflow (a flux down plant stems). 11 Pollen deposition may also alter the organismal community on plant surfaces, changing other 12 biological particulates transported by throughfall and stemflow. We report concentrations and 13 fluxes of pollen and other biological particulates (flagellate cells, nematodes, rotifers, mites and 14 hexapodans) in throughfall and stemflow from an understory forb, Eupatorium capillifolium 15 (Lam. dogfennel), during a Pinus palustris (Mill. longleaf pine) pollen shedding event, then 16 compare these results to observations collected when pollen was absent. Pollen flux was 95.6 x 17 106 grains ha-1 season-1 from dogfennel canopies (63% and 37% transported by throughfall and 18 stemflow, respectively), representing 0.1-3.2 g ha-1. Median concentrations in flagellates, 19 nematodes and rotifers for throughfall and stemflow were higher during pollen shedding; 20 however, mites and hexapodan concentrations were similar regardless of pollen presence. This 21 is the first report of flagellate and hexapodan concentrations in canopy drainage waters. 22 Flagellate concentrations were higher than for other organisms—being similar to those 23 reported for streams, 105-107 cells L-1—and hexapodan fluxes were ~50 individuals m-2 per 1 cm 24 of rainfall. These results indicate that throughfall and stemflow can (i) transport ecologically 25 relevant amounts of pollen and organisms from the phyllosphere to the surface, and (ii) that 26 the composition and flux of biological particulates can change markedly during pollen shedding.
Preparation of Silica Gel Obtained From Early Cretaceous Sidi Aich Sands (Central Tunisia)
Authors: Lazaar Khalil , Pullar Robert , Hajjaji Walid , Jamoussi Fakher 
Published: February 2021

Abstract
The study describes the chemical–mineralogical characterization of Barremian sand deposits. These Sidi Aich sands were collected in central Tunisia. The collected raw silica sand from the Jebel Meloussi (central Tunisia) was characterised by different techniques, such as X-ray diffraction (XRD), X-ray fluorescence (XRF) and scanning electron microscopy (SEM). X-ray diffraction showed a predominance of quartz and potassic feldspars and lower amounts of kaolinite and calcite. The obtained silica gels had pore diameters over 20 Å and specific surface areas up to 183 m2/g, close to those reported for commercial silica gel materials. The N2 adsorption isotherms have shown that new materials synthesised from Tunisian silica sands are mesoporous materials with high chemi-physical adsorption capabilities.
Prevalence and Recurrence Rates of Cytomegalovirus Infection among Patients with Hematological Diseases of the Brazilian Western Amazon
Authors: Silva Jean Melo , Pinheiro-Silva Renato , Oliveira Regiane Costa de , Alves Carlos Eduardo De Castro , Barbosa Anderson Nogueira , Pontes Gemilson 
Published: February 2021

Abstract
Purpose: Cytomegalovirus (CMV) is a worldwide distributed pathogen that may cause serious complications in patients with hematological diseases. This study aimed to serologically characterize the CMV infection in patients suffering from hematological diseases in Amazonas, Brazil.
Methods: Serum samples from 323 patients were tested for the presence of anti-CMV IgM or IgG antibodies by an enzyme-linked immunosorbent assay. Positive samples for IgM were submitted to the IgG avidity test to differentiate primary infection from recurrent infection. An epidemiological questionnaire was administered to collect sociodemographic information of the study population.
Results: The overall prevalence of CMV infection verified in this study was 91.3%. The highest rates were found in patients suffering from platelet disorders (94.5%), anemia (93.3%), or leukemia (91%). The study population was predominantly composed of individuals with low socioeconomic status. Blood transfusions were more often in patients with anemia or leukemia, but it was not correlated with the positivity for CMV infection. Measurement of IgG avidity in patients positive for anti-CMV IgM demonstrated a recurrent infection rate of 5.2% (17/323). Over 80% of recurrent infection occurred in patients with acute lymphocytic leukemia (ALL) or anemia.
Conclusions: Our findings indicated that CMV infection is highly prevalent in patients with hematological diseases from the Brazilian western Amazon. The prevalence observed progressively rose with increasing age, whereas anemia or ALL disease figured as risk factors for the recurrence of CMV infection.
The prevalence and socio-demographic risk factors of coexistence of stunting, wasting and underweight among children under five years in Bangladesh
Authors: Chowdhury Mohammad Rocky Khan , Rahman Md Shafiur , Billah Baki , Kabir Russell , Perera Nirmala K. P. , Kader Manzur 
Published: February 2021

Abstract
Background

Childhood malnutrition in all its forms is a significant public health challenge for developing countries like Bangladesh. There is a gap in knowledge of the coexistence of various forms of malnutrition among children under five years (under-5) in Bangladesh. This study aims (i) describe prevalence and risk factors for the coexistence of stunting, wasting and underweight among children under-5 in Bangladesh.
Methods

This study included 6,610 and 7,357 under-5 children from Bangladesh Demographic Health Surveys (BDHS) 2014 and 2017/18 respectively. Associations between coexistence stunting, wasting and underweight and socio-demographic factors were assessed by the Chi-square test and negative binomial regression.
Results

The prevalence of coexistence of stunting, wasting and underweight gradually declined from 5.2% in 2014 to 2.7% in 2017/18. Children of uneducated mothers ((Adjused incidence rate ratio (aIRR) 5.0, 95% CI 2.3, 11.0)); with low birth weights (aIRR 2.7, 95% CI 1.4, 5.1); children of age group 36–47 months (aIRR 2.5, 95% CI 1.5, 4.1); and children of underweight mothers (aIRR 1.9, 95% CI 1.4, 2.7) were the most important risk factors. However, maternal educational status was not associated with coexistence of stunting, wasting and underweight among children under-5 in 2014 whereas in 2017/18 it was the most influential risk factor. Moreover, watching television less than once a week increased the risk of coexistence of stunting, wasting and underweight by 54% (aIRR 1.54, 95% CI 1.0, 2.4).
Conclusions

one out of thirty-five under-5 children were identified to have coexistence of stunting, wasting and underweight in Bangladesh. The burden of malnutrition was disproportionate among uneducated mother, underweight mother, low birth weight and socio-economically poorest household. Our study indicates that there is a need for multi-level interventions from household level to societal level to reduce consequences of childhood malnutrition.
Changes in air-pollution related behaviour measured by Google Trends Search Volume Index in response to reported air quality in Poland
Authors: Nazar Wojciech , Plata-Nazar Katarzyna 
Published: February 2021

Abstract
Background
Decreased air quality is connected to a higher number of hospital admissions and an increase in daily mortality rates. Thus, Poles’ behavioural response to sometimes elevated air pollution levels is vital. The aim of this study was to carry out analysis of changes in air-pollution related information seeking behaviour in response to nationwide reported air quality in Poland.
Methods
Google Trends Search Volume Index data was used to investigate Poles’ interest in air pollution-related keywords. PM10 and PM2.5 concentrations measured across Poland between 2016 and 2019 were collected from the Chief Inspectorate of Environmental Protection databases. Pearson Product-Moment Correlation and the R2 correlation coefficient of determination were used to measure spatial and seasonal correlations between reported air pollution levels and the popularity of search queries.
Results
The highest PM10 and PM2.5 concentrations were observed in southern voivodeships and during the winter season. Similar trends were observed for Poles’ interest in air-pollution related keywords. All R2 coefficient of determination values were > 0.5 and all correlations were statistically significant.
Conclusion
Poland’s air quality does not meet the World Health Organisation guidelines. Also, the air quality is lower in southern Poland and during the winter season. It appears that Poles are aware of this issue and search for daily air quality data in their location. Greater interest in air quality data in Poland strongly correlates with both higher regional and higher seasonal air pollution levels.
Health System Factors That Influence Treatment Delay in Women With Breast Cancer in Sub-saharan Africa: A Systematic Review
Authors: Gbenonsi Gloria , Boucham Mouna , Belrhiti Zakaria , Nejjari Chakib , Huybrechts Inge , Khalis Mohamed 
Published: February 2021

Abstract
BackgroundBreast cancer patients in sub-Saharan Africa experience long delays between their first presentation to a health care facility and the start of cancer treatment. The role of the health system in the increasing delays in treatment has not been widely investigated. This review aimed to identify existing information on health system factors that influence treatment delays in women with breast cancer in sub-Saharan Africa to contribute to the reorientation of health policies in the region.MethodsPubMed, ScienceDirect, African Journals Online, Mendeley, ResearchGate and Google Scholar were searched to identify relevant studies published between 2010 and July 2020. We performed a qualitative synthesis in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Related health system factors were extracted and classified according to the World Health Organization’s six health system building blocks. The quality of qualitative and quantitative studies was assessed by using the Critical Appraisal Skills Program quality-assessment tool and the National Institute of Health Quality Assessment Tool, respectively. In addition, we used the Confidence in the Evidence from Reviews of Qualitative Research tool to assess the evidence for each qualitative finding.ResultsFrom 14,184 identified studies, this systematic review included 28 articles. We identified a total of 36 barriers and 8 facilitators that may influence treatment delay in women with breast cancer. The principal health system factors identified were mainly related to human resources and service delivery, particularly difficulty accessing health care, diagnostic errors, poor management, and treatment cost.ConclusionThe present review shows that treatment delay among women with breast cancer in sub-Saharan Africa is influenced by many related health system factors. Policy makers in sub-Saharan Africa need to tackle the financial accessibility to breast cancer treatment by adequate universal health coverage policies and reinforce the clinical competencies for health workers to ensure timely diagnosis and appropriate care for women with breast cancer in this region.
Detection of parathyroid adenomas with 4DCT: Towards a true four-dimensional technique
Authors: Raeymaeckers Steven , De Brucker Yannick , Vanderhasselt Tim , Buls Nico , De Mey Johan 
Published: February 2021

Abstract
Background. 4DCT is a commonly performed examination in the management of primary hyperparathyroidism, combining three-dimensional imaging with enhancement over time as the fourth dimension. We propose a novel technique consisting of 16 different contrast phases, instead of three or four different phases. The main aim of this study was to see if this protocol allows for the detection of parathyroid adenomas within dose limits. Our secondary aim was examining the enhancement of parathyroid lesions over time.Methods. For this prospective study, we included 15 patients with primary hyperparathyroidism prior to surgery. We obtain a 4DCT with 16 different phases: an unenhanced phase followed by 11 consecutive arterial phases and 4 venous phases. Centered on the thyroid, continuous axial scanning is performed over a fixed 8cm or 16cm coverage volume after start of contrast administration.Results. In all patients an enlarged parathyroid can be demonstrated, mean lesion size is 13.6mm. Mean peak arterial peak enhancement for parathyroid lesions is 384 HU compared to 333 HU for the normal thyroid. No statistical difference could be found. Time to peak (TTP) is significantly earlier for parathyroid adenomas compared to normal thyroid tissue: 30.8s versus 32.3s (p value 0.008). Mean Slope of Increase (MSI) of the enhancement curve is significantly steeper compared to normal thyroid tissue: 29.8% versus 22.2% (p value 0.012). Mean dose length product was 890.7 mGy.cm with a calculated effective dose of 6.7 mSv.Conclusion. We propose a feasible 4DCT scanning-protocol for the detection of parathyroid adenomas. We manage to obtain a multitude of phases, allowing for a dynamic evaluation within an acceptable exposure range when compared to classic helical 4DCT. Our 4DCT protocol may allow for a better visualization of the pattern of enhancement of parathyroid lesions, as enhancement over time curves can be drawn. This way wash-in and wash-out of contrast in suspected lesions can be readily demonstrated. Motion artifacts are less problematic as multiple phases are available.
The impact of metastable intermolrecular nanocomposite particles on kinetic decomposition of heterocyclic nitramines using advanced solid-phase decomposition models
Authors: Elbasuney Sherif , Hamed Abdelaziz , Yehia M. , Ramzy Hesham , Abdelgawad Ahmed , Gobara Mohamed , Mokhtar Mohamed 
Published: February 2021

Abstract
Oxygen atoms on the surface of oxide catalysts have low coordination number; they are negatively charged. Surface oxygen can act active sites for decomposition of energetic nitramines (i.e. HMX); additionally hydrous surface can release active ȮH radicals. Colloidal oxide particles can fulfil these requirements. Furthermore oxide particles can induce thermite reaction with aluminium particles. This study reports on the facile fabrication of colloidal ferric oxide particles of 5 nm; Colloidal Fe2O3/Al binary mixture was integrated into HMX matrix via co-precipitation technique; uniform dispersion of nanothermite particles was verified using SEM. Naonothermite particles experienced dramatic change in HMX thermal behaviour with an increase in total heat release by 63 %. The impact of themrite particles on HMX kinetic decomposition was evaluated using an integral isoconversional method of KAS, and Kissinger models. The mean value of apparent activation was reduced by 23.5 % and 24.3 % using Kissinger and KAS models respectively. This dramatic change in HMX decomposition can be ascribed to the ferric oxide reactivity and the facile integration of colloidal thermite particles.
Cost-Utility Analysis of Expanding Hepatitis B Vaccination among Healthcare Workforce in Ethiopia
Authors: Tewihubo Dinksew , Gebrehans Micheale , Asmamaw Getahun 
Published: February 2021

Abstract
Objective: Three doses of monovalent Hepatitis B vaccinations that given for six months were the most effective as well as a safe way to prevent Hepatitis B viral infection. Ethiopia is one of the countries with high endemicity of Hepatitis B infection. Hence, examining cost-utility analysis of hepatitis B vaccination coverage among healthcare workers in Ethiopia was found the most essential work.
Method: : Markov model for expanding vaccination coverage (3 doses of hepatitis B vaccine) was simulated based on the data obtained from black lion specialized hospitals and distinctive works of literature. In Ethiopia, the current vaccine coverage among health care workers accounts for around 14%. Most health workforce (241,250) of Ethiopia was first considered as susceptible with a probability of getting Hepatitis B Virus acutely and 5-10% chance of progressing to chronic Hepatitis B. This study was conducted from a healthcare payer perspective, with 3% discount rate of cost and health outcome as WHO recommendation. Primarily health outcome was measured by QALY gain and ICER. Deterministic analysis and tornado diagrams were employed to manage parameter uncertainty and show a plausible range of cost and effectiveness of variables obtained from published articles and black lion specialized hospitals.
Result: Current vaccination program is more expensive (US$29.99) with a positive incremental cost of US$ 1.32 and less effective that have negative incremental effectiveness of -0.08 and total life year gains of 28.54 than Expanded Hepatitis B vaccination strategy which costs US$ 28.67 and gives relatively high total life-year gain of 28.62. The resulting ICER was US$ 16.23 per QALY gained. Hence, ICER was a negative current vaccination strategy that was dominated which means that is a more expensive and less effective strategy. One-way sensitivity analysis provides that the current vaccine coverage was dominated for an increase in the risk of infection among unvaccinated individuals.
Conclusion: Increasing current vaccine coverage from 14% to 80% among all Ethiopian all healthcare workforces was the most cost-effective strategy.