bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association between depression, anxiety, and insomnia with musculoskeletal pain source: a multi-center study
Authors: Zarean Elham , Azadeh Asma , Pirali Habib , Doroushi Behzad , Edrisi Atieh , Ahmadi Ali , Baharizadeh Alireza , Torkian Samaneh 
Published: January 2021

Abstract
Background
Musculoskeletal pain syndrome (MPS) is one of the modern diseases. Musculoskeletal pain (MP) may develop at any age and impact physical and mental health. This study aimed to evaluate the association between anxiety, depression, and insomnia with musculoskeletal pain source. This cross-sectional study was conducted on 450 patients with musculoskeletal pain. Goldberg depression (GB), Beck Anxiety Inventory (BAI), and Morin Insomnia Severity Index (ISI) questionnaires were used to collect data. Participants have divided into two groups: individuals with unknown musculoskeletal pain sources and individuals with known musculoskeletal pain sources. Anxiety, depression, and insomnia scores were compared between the two groups. For statistical analysis of data mean (SD), frequency (%), Chi-square, Mann-Whitney test, and Logistic regression models were used. All analysis was performed using SPSS 26.

Results
In this study, 39.4% of the participants were in severe depression, 31.1% in severe anxiety, 34.7% in the no clinically significant, and 32.9% in the sub-threshold insomnia group. There was a significant difference between the severity of anxiety and insomnia in the two groups with the known and unknown pain sources (p < 0.05). However, the score of depression (OR = 1.00, 95% CI 0.99–1.01), anxiety (OR = 1.00, 95% CI 0.99–1.02), and insomnia (OR = 1.01, 95% CI 0.98–1.03) was not related to the pain source.

Conclusion
There was a statistically significant relationship between anxiety and insomnia severity with musculoskeletal pain source. According to the high prevalence of depression, anxiety, and depression in both groups with known and unknown musculoskeletal pain sources, the cooperation of orthopedists, rheumatologists, and physical therapists with psychiatrist can be useful in improving the condition of patients.
Electrically inferred subsurface fractures in the crystalline hard rocks of an Experimental Hydrogeological Park, Southern India
Authors: Maurya Ved Prakash , Chandra Subash , Sonkamble Sahebrao , Lohithkumar Kethavath , Nagaiah Erugu , Selles Adrien 
Published: January 2021

We have investigated a network of fractures forming the flow paths within the crystalline granitic rocks of an Experimental Hydrogeological Park (EHP) with the help of electrical resistivity surveys. The experimental study located at the managed aquifer recharge (MAR) site of EHP has measured a distinct variation in the apparent resistivity for deeper electrical signals that localize the presence of interconnected water-saturated fractures. Usually, profiles close to the MAR tank depict low apparent resistivity values from deep signals across in situ fractures and resistivity amplitude increases away from the tank. We modeled and simulated the presence of water-saturated fractures by a simple three-layered model having embedded shallow heterogeneities in the saprolite layer, vertically interconnected multiple thin conductive horizontal layers in the fissured zone, and an underlain unweathered crystalline granitic basement. These fractures produce a distinct variation in the resistivity for modeling and inversion exercises. The decadal time-lapse electrical resistivity surveys, after the establishment of the MAR tank, mark similar repetitive main features with a distinct drop in resistivity depicting the presence of water-saturated fractures. An overview of the 3D resistivity model characterizes the subsurface heterogeneities and the presence of possible flow paths for shallow depths <30 m, and it is indicative of possible flows in the interconnected deep fractures for depths >30 m.
Burkitt Lymphoma International Prognostic Index
Authors: Olszewski Adam J. , Jakobsen Lasse H. , Collins Graham P. , Cwynarski Kate , Bachanova Veronika , Blum Kristie A. , Boughan Kirsten M. , Bower Mark , Dalla Pria Alessia , Danilov Alexey , David Kevin A. , Diefenbach Catherine , Ellin Fredrik , Epperla Narendranath , Farooq Umar , Feldman Tatyana A. , Gerrie Alina S. , Jagadeesh Deepa , Kamdar Manali , Karmali Reem , Kassam Shireen , Kenkre Vaishalee P. , Khan Nadia , Kim Seo-Hyun , Klein Andreas K. , Lossos Izidore S. , Lunning Matthew A. , Martin Peter , Martinez-Calle Nicolas , Montoto Silvia , Naik Seema , Palmisiano Neil , Peace David , Phillips Elizabeth H. , Phillips Tycel J. , Portell Craig A. , Reddy Nishitha , Santarsieri Anna , Sarraf Yazdy Maryam , Smeland Knut B. , Smith Scott E. , Smith Stephen D. , Sundaram Suchitra , Zayac Adam S. , Zhang Xiao-Yin , Zhu Catherine , Cheah Chan Y. , El-Galaly Tarec C. , Evens Andrew M. 
Published: January 2021

PURPOSEBurkitt lymphoma (BL) has unique biology and clinical course but lacks a standardized prognostic model. We developed and validated a novel prognostic index specific for BL to aid risk stratification, interpretation of clinical trials, and targeted development of novel treatment approaches.METHODSWe derived the BL International Prognostic Index (BL-IPI) from a real-world data set of adult patients with BL treated with immunochemotherapy in the United States between 2009 and 2018, identifying candidate variables that showed the strongest prognostic association with progression-free survival (PFS). The index was validated in an external data set of patients treated in Europe, Canada, and Australia between 2004 and 2019.RESULTSIn the derivation cohort of 633 patients with BL, age ≥ 40 years, performance status ≥ 2, serum lactate dehydrogenase > 3× upper limit of normal, and CNS involvement were selected as equally weighted factors with an independent prognostic value. The resulting BL-IPI identified groups with low (zero risk factors, 18% of patients), intermediate (one factor, 36% of patients), and high risk (≥ 2 factors, 46% of patients) with 3-year PFS estimates of 92%, 72%, and 53%, respectively, and 3-year overall survival estimates of 96%, 76%, and 59%, respectively. The index discriminated outcomes regardless of HIV status, stage, or first-line chemotherapy regimen. Patient characteristics, relative size of the BL-IPI groupings, and outcome discrimination were consistent in the validation cohort of 457 patients, with 3-year PFS estimates of 96%, 82%, and 63% for low-, intermediate-, and high-risk BL-IPI, respectively.CONCLUSIONThe BL-IPI provides robust discrimination of survival in adult BL, suitable for use as prognostication and stratification in trials. The high-risk group has suboptimal outcomes with standard therapy and should be considered for innovative treatment approaches.
Association of Diabetes Subgroups With Race/Ethnicity, Risk Factor Burden and Complications: The MASALA and MESA Studies
Authors: Bancks Michael P , Bertoni Alain G , Carnethon Mercedes , Chen Haiying , Cotch Mary Frances , Gujral Unjali P , Herrington David , Kanaya Alka M , Szklo Moyses , Vaidya Dhananjay , Kandula Namratha R 
Published: January 2021

Abstract

Introduction
There are known disparities in diabetes complications by race and ethnicity. Although diabetes subgroups may contribute to differential risk, little is known about how subgroups vary by race/ethnicity.

Methods
Data were pooled from 1293 (46% female) participants of the Mediators of Atherosclerosis in South Asians Living in America (MASALA) and the Multi-Ethnic Study of Atherosclerosis (MESA) who had diabetes (determined by diabetes medication use, fasting glucose, and glycated hemoglobin [HbA1c]), including 217 South Asian, 240 non-Hispanic white, 125 Chinese, 387 African American, and 324 Hispanic patients. We applied k-means clustering using data for age at diabetes diagnosis, body mass index, HbA1c, and homeostatic model assessment measures of insulin resistance and beta cell function. We assessed whether diabetes subgroups were associated with race/ethnicity, concurrent cardiovascular disease risk factors, and incident diabetes complications.

Results
Five diabetes subgroups were characterized by older age at diabetes onset (43%), severe hyperglycemia (26%), severe obesity (20%), younger age at onset (1%), and requiring insulin medication use (9%). The most common subgroup assignment was older onset for all race/ethnicities with the exception of South Asians where the severe hyperglycemia subgroup was most likely. Risk for renal complications and subclinical coronary disease differed by diabetes subgroup and, separately, race/ethnicity.

Conclusions
Racial/ethnic differences were present across diabetes subgroups, and diabetes subgroups differed in risk for complications. Strategies to eliminate racial/ethnic disparities in complications may need to consider approaches targeted to diabetes subgroup.
Η μνήμη της κρίσης: Κοινωνικές συνιστώσες της οικονομικής ύφεσης στον επιστημονικό και βιωματικό λόγο
Authors: Souyioultzoglou Irakleitos , Angelaki Marina 
Published: January 2021

Το παρόν άρθρο βασίζεται σε μια διευρυμένη αντίληψη των κρίσεων ως πρωταρχικά κοινωνικών φαινομένων. Εστιάζοντας στη λογοθετική δυναμική της ελληνικής κρίσης, προτείνει μια μεθοδολογική προσέγγιση που βασίζεται στη συγκριτική ερμηνεία των λόγων για την «κρίση» ως αναλυτική κατηγορία και κοινωνικό φαινόμενο, καθώς και στις συγκλίνουσες ή/και αποκλίνουσες αναφορές των βιωματικών μαρτυριών και της επιστημονικής αρθρογραφίας σχετικά με τις πολλαπλές όψεις της. Προσεγγίζοντας την ελληνική κρίση σημειολογικά, ως πεδίο διαμόρφωσης εννοιών και αντιλήψεων, ανατρέχουμε σε δημοσιεύσεις που υποδεικνύουν την πολυπλοκότητα των επιπτώσεών της στην καθημερινότητα, επιχειρώντας να αναδείξουμε τους τρόπους με τους οποίους το κοινωνικό στίγμα της κρίσης αποδίδεται στον επιστημονικό λόγο. Παράλληλα, αξιοποιώντας το πρωτογενές υλικό που έχει συγκεντρωθεί από τις Ομάδες Προφορικής Ιστορίας, αναζητούμε το αποτύπωμα της κρίσης στις μαρτυρίες και τους όρους διαμόρφωσης του συλλογικού αφηγήματος για την κρίση, υπό το πρίσμα των εγγενών χαρακτηριστικών της ελληνικής κοινωνίας και της κοινωνικής συνείδησης των μελών της.
Ποιότητα ζωής και ψυχική υγεία των μητέρων με παιδί/ά στο φάσμα του αυτισμού: Επισκόπηση ευρημάτων
Authors: Ζήση Αναστασία , Μαυροπούλου Σοφία 
Published: January 2021

The present paper is a critical review of a representative corpus of studies extending from the ’70s until today, that examine the quality of life and mental health of parents, and especially mothers who raise at least one child with autism. This review aims at identifying the factors influencing mental health and perceived quality of life of parents withchildren within the autistic spectrum, drawing on the theoretical model of quality of life developed by Zissi & Barry (2006). This theoretical model posits that quality of life is associated with a variety of factors such as; a), objective living conditions that relate to family socio-economic status and its type, the severity of autism, and the access to therapeutic services, and b) socio-psychological processes that relate to the different explanatory models, the hardiness, the general life outlook and the quality of ties. This model predicts that socio-psychological processes mediate the relationship between objective living conditions, mental health and subjective evaluations of quality of life.
DISCUSSION - Positive Psychology: Small steps towards renewing and expanding the sound tradition of subjectivity
Authors: Kordoutis Panos 
Published: January 2021

The basic tenets of Positive Psychology derive from the philosophical traditions of Utilitarianism, Virtues, and Eudaimonia theorizing, and Hedonism. However, its unique and original contribution to Psychology lies in empirically operationalizing the definition of well-being. Moreover, it has proposed a theoretical framework consisting of, also, operationally defined socio-psychological processes associated with well-being: (a) interacting within social relationships and contexts, (b) developing traits (e.g. personal strengths), (c) pursuing states of existence (happiness, pleasure) and (d) experiencing seamless functioning (e.g. meaning). These processes concern and render with theoretical cohesion most of the research and interventions within Positive Psychology. Nevertheless, and even though social and relational contexts have been an integral part of the cohesive model of Positive Psychology from the outset, rarely are they reflected in pertinent research in a way other than that of subjective representations. The six papers presented in this journal fall into the aforementioned fourfold cohesive theoretical approach of Positive Psychology and nearly all, respond to the above criticism by taking into account relational or social contextual factors and by employing different strategies for their representation or actual estimation.. All papers in this special issue are good examples of how evidence-based understanding can support and feed into effective intervention planning and applications, a goal that follows steadily Positive Psychology since its inception.
Editorial
Authors: Das Rolla 
Published: January 2021

In an excellent article, “Struggling with the uncertainty of life under coronavirus? How Kierkegaard’s philosophy can help”, published in The Conversation, Patrick Stokes, presents an analysis of life and uncertainty during COVID 19 in the world. The world, people, their lives, dreams and aspirations, the very possibility of a future, the nature and reality of it faced an enormous challenge – the challenge of presence, or the existence or being after the pandemic. This could be because many of us could not conceive what after meant. New vocabulary, newer appearances and still newer methods of communication alerted to a “new normal”. Many students, teachers, workers from all spheres of life, people in general, did not always felt jubilant with the attempted vibrancy of the term, “now normal”. People waited.
Estimates of Victim Surface Area and Associated Extraction Force for Partial Entrapment in Grain
Authors: Schwab Charles V. , Schwab Lauren E. , Schwab Pamela J. 
Published: January 2021

HighlightsEight selected anthropometric landmarks were useful for estimating victim surface area and entrapment depth.Surface area estimates for a partially entrapped male victim ranged from 0.0716 to 2.7296 m2.Partial extraction force estimates for a male victim ranged from 0.29 to 3,693 N.Partial extraction force estimates were 18% greater on average when including the arm surface area than when not including the arms.Abstract. A prediction model for estimating extraction forces on entrapped victims was enhanced and modernized in 2018 from the original 1985 model. The prediction model was divided into two conditions based on the victim’s relative position to the grain surface. The first condition was when the victim is completely below the grain surface. The second condition was when the victim’s shoulders are above the grain surface; this condition is the focus of this research. A variable in the prediction model that changes with the depth of entrapment is the surface area of the victim. A sample of 60 male models was used to approximate the human surface area at optimal discrete positions selected based on visually identifiable anthropometric landmarks. The surface area estimates for those 60 partially entrapped male models ranged from 0.0716 to 2.7296 m2. Extraction forces for twelve partially entrapped male body types with various combinations of stature and body mass index were calculated. The extraction forces were calculated for conditions when the victim’s arms were raised (above the grain) and lowered (in the grain). Results from the prediction model showed that surface area contributed less to the partial extraction force for short underweight bodies than for tall extremely obese bodies. At the lower landmarks, i.e., medial malleolus (MM) and knee crease (KN), surface area did not contribute noticeably to the partial extraction force. The contribution of surface area was not noticeable until the victim was buried up to the crotch (landmark CR). Keywords: Farm safety, Grain entrapment, Prediction model, Rescue, Safety.
Approximation of a melting plateau of large area HTFP cells used for
spectral irradiance realization
Authors: Xie Yihang , Dai Caihong , Wang Yanfei , Wu Zhifeng , Li Ling , Khlevnoy Boris , Grigoryeva Irina , He Shufang , Lin Yandong 
Published: January 2021

This paper adopted an approximation of a melting plateau to solve the
problem that temperature data cannot be monitored continuously when
measuring the spectral irradiance of a large area tungsten
carbide–carbon high-temperature fixed-point blackbody at each measured
wavelength. Tests with fully measured curves showed that the method
has a rather small deviation from the measured data of 0.017 K
maximum, which corresponds to the spectral irradiance deviation of
0.005% at 500 nm. The maximum relative deviation between the Akima
fitting method and the measured temperature in terms of spectral
irradiance was 0.002%, which was better than

−

0.067

%

of a single temperature of 3020.11 K
method and 0.026% of a linear interpolation method.
The effect of baseline serum uric acid on chronic kidney disease in normotensive, normoglycemic, and non-obese individuals: A health checkup cohort study
Authors: Son Young-Bin , Yang Ji Hyun , Kim Myung-Gyu , Jo Sang Kyung , Cho Won Yong , Oh Se Won 
Published: January 2021

Introduction
The independent role of serum uric acid (SUA) on kidney disease is controversial due to its association with metabolic syndrome. The objective of this study was to investigate the association of baseline SUA with development of chronic kidney disease and eGFR decline in normotensive, normoglycemic and non-obese individuals during follow up period.

Materials and methods
We included non-hypertensitive, non-diabetic, and non-obese 13,133 adults with estimated glomerular filtration rate (eGFR) ≥ 60ml/min/1.73m2 who had a voluntary health check-up during 2004–2017.

Results
SUA was positively related to adjusted means of systolic blood pressure (SBP), triglyceride, body mass index, and body fat percent. SUA was inversely associated with high density lipoprotein HDL (P for trend ≤0.001). SUA was an independent risk factor for the development of diabetes, hypertension, and obesity. During 45.0 [24.0–76.0] months of median follow up, the highest quartiles of SUA showed significant risks of 30% eGFR decline compared than the lowest quartile (RR:3.701; 95% CI: 1.504–9.108). The highest quartile had a 2.2 fold (95% CI: 1.182–4.177) increase in risk for incident chronic kidney disease (CKD).

Conclusions
SUA is an independent risk factor for the development of diabetes, hypertension, and obesity in the healthy population. High SUA is associated with increased risk of CKD development and eGFR decline in participants with intact renal function.
Psychological outcomes, knowledge and preferences of pregnant women on first-trimester screening for fetal structural abnormalities: A prospective cohort study
Authors: Bardi Francesca , Bakker Merel , Kenkhuis Monique J. A. , Ranchor Adelita V. , Bakker Marian K. , Elvan Ayten , Birnie Erwin , Bilardo Caterina M. 
Published: January 2021

Introduction
The primary aim of this study is to investigate the impact of a 13-week anomaly scan on the experienced levels of maternal anxiety and well-being. Secondly, to explore women’s knowledge on the possibilities and limitations of the scan and the preferred timing of screening for structural abnormalities.

Material and methods
In a prospective-cohort study conducted between 2013–2015, pregnant women in the North-Netherlands underwent a 13-week anomaly scan. Four online-questionnaires (Q1, Q2, Q3 and Q4) were completed before and after the 13- and the 20-week anomaly scans. In total, 1512 women consented to participate in the study and 1118 (74%) completed the questionnaires at Q1, 941 (64%) at Q2, 807 (55%) at Q3 and 535 (37%) at Q4. Psychological outcomes were measured by the state-trait inventory-scale (STAI), the patient’s positive-negative affect (PANAS) and ad-hoc designed questionnaires.

Results
Nine-nine percent of women wished to be informed as early as possible in pregnancy about the absence/presence of structural abnormalities. In 87% of women levels of knowledge on the goals and limitations of the 13-week anomaly scan were moderate-to-high. In women with a normal 13-week scan result, anxiety levels decreased (P < .001) and well-being increased over time (P < .001). In women with false-positive results (n = 26), anxiety levels initially increased (STAI-Q1: 39.8 vs. STAI-Q2: 48.6, P = 0.025), but later decreased around the 20-week anomaly scan (STAI-Q3: 36.4 vs. STAI-Q4: 34.2, P = 0.36).

Conclusions
The 13-week scan did not negatively impact the psychological well-being of pregnant women. The small number of women with screen-positive results temporarily experienced higher anxiety after the scan but, in false-positive cases, anxiety levels normalized again when the abnormality was not confirmed at follow-up scans. Finally, most pregnant women have moderate-to-high levels of knowledge and strongly prefer early screening for fetal structural abnormalities.
A systematic review and meta-analysis reveal that Campylobacter spp. and antibiotic resistance are widespread in humans in sub-Saharan Africa
Authors: Hlashwayo Delfina F. , Sigaúque Betuel , Noormahomed Emília V. , Afonso Sónia M. S. , Mandomando Inácio M. , Bila Custódio G. 
Published: January 2021

Introduction
Campylobacter spp. are zoonotic bacteria that cause gastroenteritis in humans worldwide, whose main symptom is diarrhea. In certain cases, extra intestinal manifestations may occur, such as Guillain Barré syndrome. The bacteria cause severe diarrhea mostly in children and in immunocompromised individuals. This review aims to address the prevalence of Campylobacter spp. in humans in sub-Saharan Africa. It also aims to understand the impact of HIV in the prevalence, as well as to report data on antibiotic resistance and propose research priorities.

Methods
We followed PRISMA guidelines to find studies on the occurrence of Campylobacter spp. in humans in all countries from sub-Saharan Africa. Studies published between 2000 and 2020 were searched in PubMed, Cochrane Library, CINAHL, African Index Medicus, African Journals Online, Google Scholar and Science Direct. We have conducted a random-effect meta-analysis and calculated the proportion of resistant isolates to different antibiotics.

Results and discussion
We found 77 studies that described such occurrence in humans in 20 out of 53 sub-Saharan African countries. Campylobacter jejuni was the most prevalent species. Pooled prevalence was 9.9% (CI: 8.4%–11.6%). No major variations within the different sub-regions were found. Most studies reported Campylobacter spp. as the cause of diarrhea, mainly in children. Some studies reported the bacteria as a possible etiologic agent of acute flaccid paralysis and urinary tract infection. Campylobacter spp. presented a higher pooled prevalence in HIV infected patients, although not statistically significant. High proportions of resistant strains were reported for many antibiotics, including erythromycin and tetracycline.

Conclusion
Campylobacter spp. occur in sub-Saharan Africa, although information is scarce or inexistent for many countries. Research priorities should include investigation of the understudied species; extra intestinal manifestations; the impact of HIV infection and associated risk factors. Control strategies should be reinforced to contain the spread of this pathogen and drug resistance.