bluuebunny/crossref_metadata_2025_split huggingface dataset:
Root Loci Analysis of a Simple Quasi-Polynomial And Its Use For Relay-Based Parameter Identification of a Delayed Infinite-Dimensional Heat-Exchanger Process
Authors: Pekař Libor , Song Mengjie , Padhee Subhransu , Dostálek Petr , Zezulka František 
Published: October 2021

Abstract
The focus of this contribution is twofold. The first part aims at the rigorous and complete analysis of pole loci of a simple delayed model, the characteristic function of which is represented by a quasi-polynomial with a non-delay and a delay parameter. The derived spectrum constitutes an infinite set, making it a suitable and simple-enough representative of even high-order process dynamics. The second part intends to apply the simple infinite-dimensional model for relay-based parameter identification of a more complex model of a heating-cooling process with heat exchangers. Processes of this type and construction are widely used in industry. The identification procedure has two substantial steps. The first one adopts the simple model with a low computational effort using the saturated relay that provides a more accurate estimation than the standard on/off test. Then, this result is transformed to the estimation of the initial characteristic equation parameters of the complex infinite-dimensional heat-exchanger model using the exact dominant-pole-loci assignment. The benefit of this technique is that multiple model parameters can be estimated under a single relay test. The second step attempts to estimate the remaining model parameters by various numerical optimization techniques and also to enhance all model parameters via the Autotune Variation Plus relay experiment for comparison. Although the obtained unordinary time and frequency domain responses may yield satisfactory results for control tasks, the identified model parameters may not reflect the actual values of process physical quantities.
An All-in-One Bio-inspired Neural Network
Authors: Radhakrishnan Shiva Subbulakshmi , Dodda Akhil , Das Saptarshi 
Published: October 2021

Abstract
In spite of recent advancements in artificial neural networks (ANNs), the energy efficiency, multifunctionality, adaptability, and integrated nature of the biological neural networks largely remain unimitated in hardware neuromorphic computing systems. Here we exploit optoelectronic, computing, and programmable memory devices based on emerging two-dimensional (2D) layered materials such as MoS2 to demonstrate a monolithically integrated, multi-pixel, and “all-in-one” bio-inspired neural network (BNN) capable of sensing, encoding, learning, forgetting, and inferring at miniscule energy expenditure. We also demonstrate learning adaptability and stimulate learning challenges under specific synaptic conditions to mimic biological learning. Our findings highlight the potential of in-memory computing and sensing based on emerging 2D materials, devices, and integrated circuits not only to overcome the bottleneck of von Neumann computing in conventional CMOS designs but also aid in eliminating peripheral components necessary for competing technologies such as memristors.
Kidney Renal Clear Cell Carcinoma: Development and Validation of Prognostic Index of Necroptosis-Related Genes
Authors: Wu zixuan , Huang Xuyan , Cai Minjie , Huang peidong , Guan Zunhui 
Published: October 2021

Abstract
Background: Renal carcinoma is a frequent kind of malignant tumour of the urinary system, and its prevalence is increasing. Methods: The predictive significance of Necroptosis-related genes (NRGs) in 539 Kidney renal clear cell carcinoma (KIRC) samples from The Cancer Genome Atlas (TCGA) datasets was investigated. We wanted to show how NRGs interact with immunological checkpoints and m6A in KIRC. In the Kyoto Encyclopedia of Genes and Genomes, gene set enrichment analysis was employed to study gene expression enrichment. Lasso regression was used to build the predictive model. According to a co-expression study, gene expression is directly related to necroptosis. In the absence of additional clinical signs, NRGs was shown to be partly overexpressed in high-risk individuals, indicating that they might be used in a model to predict KIRC prognosis. GSEA identified immunological and tumour-related pathways in the high-risk group. Results: According to TCGA, immune checkpoint and m6A genes differ considerably between the low-risk and high-risk groups. PLA2G4D, H2AC17, H2AC7, IRF9, and other genes varied between the two risk groups. NRGs are linked to the onset and development of KIRC. Conclusions: Using matching predictive models, the prognosis of KIRC patients may be predicted. NRGs and the association of immunological checkpoints and m6A with NRGs in KIRC may represent potential therapeutic targets that should be investigated further.
Adipose-derived Mesenchymal Stem Cell Therapy for Reverse Bleomycin-induced Experimental Pulmonary Fibrosis
Authors: Zhao Xiansheng , Wu Jinyan , Yuan Ruoyue , Li Yue , Yang Quyang , Wu Baojin , Zhai Xiaowen , Wang Jiucun , Magalon Jérémy , Zhu Winston M , Zhu NingWen 
Published: October 2021

Abstract
Background: Idiopathic pulmonary fibrosis (IPF) is a chronic progressive respiratory disease. Arguably, the complex interplay between immune cell subsets, coupled with an incomplete understanding in disease pathophysiology, have contributed to the paucity of successful therapies. In turn, IPF remains a fatal disease at present. Thus, with no effective therapy for either the prevention or treatment of IPF, the need for new therapies is paramount. Mesenchymal stromal/stem cell (MSC) therapy has shown promise in experimental models of IPF. Methods:The aim of this study was to test the therapeutic effect of adipose-derived mesenchymal stem cells in a bleomycin-induced pulmonary fibrosis model. First, MSC cells were obtained from mice, and then flow cytometry and cell differentiation culture methods were uesd to identify them. Then adult C57BL/6 mice were challenged with endotracheal instillation of bleomycin and treated with MSC concurrently for reversal models at day 14. Experimental groups were assessed at day 14, 21, or 28. Finally, lung fibroblasts were challenged with TGF-β1 and treated with MSC supernatant or MSCs to explore the relevant mechanisms of pulmonary fibrosis reversal. Results:We successfully obtained mesenchymal stem cells from mouse adipose tissue and identified their differentiation ability and cell phenotype.We found that the presence of MSC or its supernatant could promote the proliferation and migration of lung fibrotic cells. Meanwhile, MSC supernatant could reduce lung collagen deposition, improve Ashcroft score, and reduce the gene and protein content of lung fibrosis-related substances. Bleomycin-challenged mice presented with severe septal thickening and prominent fibrosis, and this was effectively reversed by MSC treatment.Conclusions: In summary, this study found that MSC therapy can prevent and revert the core features of bleomycin-induced pulmonary fibrosis, and the beneficial effects of MSC may be mediated via its paracrine-related cytokines. It provides further evidence for the importance of the MSC in cell therapy medicine applications.
Experimental and Numerical Analysis of the Polyurethane Foam Effects on Geotechnical Seismic Isolation
Authors: Gatto Michele Placido Antonio , Lentini Valentina , Montrasio Lorella 
Published: October 2021

Abstract
The paper focuses on the detailed analysis of the dynamic characterisation of polyurethane to evaluate the effects of polyurethane injections into the soil with the aim of geotechnical seismic isolation (GSI). To determine the dynamic properties, resonant column (RC) tests were performed at the University Kore of Enna (Italy) on specimens of pure polyurethane (PUR) with different values of density and subjected to different mean confining pressures. The results obtained by means of RC tests, in terms of shear modulus G and the damping ratio D as a function of shear strain γc, allowed to develop an analytical formulation for G- γc and D- γc curves, taking into account the linear relationship with density of both the maximum value of shear modulus Gmax and the minimum value of damping ratio Dmin. The analytical formulation derived from the experimental results is applied for ground response seismic analyses of cohesive soils injected with polyurethane, using a finite element code. The numerical results show that the polyurethane injections reduce the value of maximum acceleration at ground surface and the reduction ranges with the thickness of the soil involved by polyurethane injection.
Preparation of Cu-BTC Supported Fly Ash-Based Catalyst and Research on Low-Temperature SCR Denitration Performance
Authors: Liu Yuling , Hao Shu 
Published: October 2021

Abstract
The novel Cu-BTC/FA materials were synthesized with Cu-BTC as the active component and solid fly ash as the catalyst carrier. then developed as the NO removing catalysts for low temperature selective catalytic reduction (SCR) with NH3. The physic-chemical properties of catalyst samples were characterized by multiple techniques, such as SEM, XRD, FTIR, XPS, TPR and Raman. The results show that: (1) The active component Cu-BTC loading ratio is 9%, the denitration performance is excellent and has strong stability. Under this condition, the catalyst showed the highest NH3-SCR activity, giving 94% NO conversion. (2) The catalysts show the good cyclic and stability in SCR denitration under 200 ℃. (3) It still shows high NO removal rate and good stability under the condition of SO2, and the denitration rate is as high as 78.36%. (4) There is a certain degree of resource integration for carrier fly ash, which not only treats air pollutants to a certain extent, but also achieves the purpose of solid waste recycling.
Creation of Elite Rice With High-yield, Superior-quality and Strong Resistance to Brown Planthopper Based on Molecular Design
Authors: Liu Manman , Fan Fengfeng , He Shihao , Guo Yu , Chen Gaili , Li Nannan , Li Nengwu , Yuan Huanran , Si Fengfeng , Yang Fang , Li Shaoqing 
Published: October 2021

Abstract
BackgroundRice is the staple food feeding for more than half of the world's population. Breeding rice with high yield, superior quality and strong resistance is the goal of breeding to meet the needs of rapidly increased population. However, it is hard to achieve the aggregation of multiple complex traits based on traditional breeding methods. ResultsHere, we report the successful development of elite rice with high yield, superior quality and strong resistance to brown planthopper (BPH) by rational molecular design. According to the function of Gn8.1, APO1, Ghd7, Ghd8 and Gn1a for large panicle, Bph6 and Bph9 for brown planthopper, GW7, GS3 and qSW5 for grain appearance quality, and Wx, ALK, SBE3, SSIV2 and SSIII for cooking and eating quality of rice, we staked all of the favorable genes together by crossing five donor lines one another. There are obvious phenotypic differences between different groups of the favorable genes. After careful screening of genotype, phenotype and genetic background, three molecular design lines were bred. The newly bred line exhibited higher yield potential, better grain quality and stronger BPH-resistance than their parents. Conclusions﻿The successful creation of elite rice with high yield, superior quality and strong resistance to BPH demonstrate that molecular design at the basis of characterized genes is an effective and powerful strategy to improve multiple complex traits, it will provide a reference for the future commercial rice improvement.
A Refined Model of a Typhoon Near-Surface Wind Field Based on CFD
Authors: Yang Youtian , Dong Lin , Li Jiazi , Li Wenli , Sheng Dan , Zhang Hua 
Published: October 2021

Abstract
Near-surface typhoon wind field simulation is a key method for high-precision typhoon hazard assessment and is of great significance for disaster forecast, loss risk assessment and emergency management. The terrain correction method for regional large-scale wind field simulation has a single correction method, which cannot satisfy the requirements of refined risk assessment. This paper aims to use the accuracy advantage of the fluid dynamics mechanism model (CFD, computational fluid dynamics) in small-scale wind speed simulation and obtain a terrain correction method suitable for regional large-scale wind field simulation by extracting the spatial change law of the wind speed under complex terrain. Among them, typical mountains with different cross-sectional shapes and different slopes are used to characterize the undulating terrain, and the CFD model is used to simulate and analyze the wind speed changes on the upwind slope, mountain top area, leeward slope, and downwind area under different initial wind speeds. The wind speed at these locations has a good quantitative relationship with the initial wind speed. Combined with the common building wind load codes in China, the wind speed correction algorithm suitable for large-scale complex terrain has been supplemented and improved. Taking Typhoon 0713 as an example, a near-surface typhoon wind field simulation was performed. Compared with other models, the accuracy of the simulation results of terrain correction by the method provided in this article has increased by 15-19.9%. The CFD-based typhoon disaster near-surface wind field can more accurately reflect the spatial distribution and intensity of typhoon wind hazards under large-scale complex terrain. It can provide technical support for the loss risk prediction and assessment of forest resources, mountain forestry economy, crops and other disaster-bearing bodies in typhoon disasters.
The Impacts of Conventional Energies on Environmental Degradation : Does Pakistan’s Economic and Environmental Model Follows Kuznets Curve?
Authors: Nizamani Rafeeque A. , Shaikh Faheemullah , Nizamani Abdul Ghafoor , Mirjat Nayyar Hussain , Kumar Laveet , Assad Mamdouh El Haj 
Published: October 2021

Abstract
This paper investigates the long-run dynamic association of carbon dioxide emissions and economic progress using the environmental Kuznets curve hypothesis for Pakistan from 1972 to 2019. The other variables used along with the above indicators are urbanization, financial development, manufacturing, oil and gas energy consumptions, and trade openness. The ARDL bounds testing methodology has been used and the results of the bounds testing showed that a 1% increase in economic growth and financial development would increase CO2 emissions in the country by 4.277% and 0.0787%, respectively. Urbanization and manufacturing would increase CO2 emissions by 0.648% and 0.171%, respectively. Oil and gas energy consumption would also increase CO2 emissions by 0.130% and 0.1935%, respectively. On the other hand, trade openness decreases emissions by -0.087% in the long run. Besides, findings confirm the EKC hypothesis with the reversed U-shape relation for per capita CO2 emissions and economic progress. However, the threshold point of the economy is approximately 2735.19$ year per capita, where economic progress can mitigate the impact of pollution lies beyond the study period. Finally, for policy implications: (i) the government should focus on economic growth by overcoming CO2 emissions as per capita income is scarce. (ii) the control and proper expansion of urban areas and empowering the inhabitants with knowledge and awareness to play their role in mitigating the effects of CO2 emissions on society. (iii) a larger share of alternative energy from biomass, the solar, wind, and other less-polluting energies in the energy need model of the country, and (iv) by establishing advanced technology-based industries in the country for economic growth by controlling the impacts on the environment.
Research on the Effectiveness of College English Teaching Based on 5G Mobile Internet
Authors: Hu Zhiyong 
Published: October 2021

Abstract
Technical assistance for the building of a distant learning environment for learning English is provided by the advancement of information technology and the educational information process. People are still getting used to online teaching method, and it is becoming more widely accepted. This article presents an optimization approach for English teaching mode in colleges based on 5G technology to overcome the constraints of the existing college English teaching mode and to increase the service scope of 5G technology. This optimization technique deviates from standard college English teaching methods and incorporates 5G technology, which significantly enhances the intelligence of English classrooms in colleges. At the same time, the optimization method may improve the quality of English teaching at colleges in a variety of ways, and implement the teaching principle of "teach students according to their ability" in a complete and systematic way. We propose an energy-efficient routing protocol for efficiently transmitting the educational data to the receiver. Also, we employ Bat Optimization Algorithm (BOA) for optimization of the transmission process. process. The students' cognitive abilities are examined. The findings demonstrate that the optimization method may not only overcome the limits of the English model in colleges, but also expand the service reach of 5G technology, therefore improving students' cognitive abilities such as listening, speaking, reading, and writing ability in various dimensions.
The role of micro-implant-assisted rapid palatal expansion (MARPE) in clinical orthodontics — a literature review
Authors: Chuang Yun-Hsuan , Chen Jen-Hsuan , Ho Kwok-Hing , Wang Kai-Long , Hsieh Shun-Chu , Chang Heng-Ming 
Published: October 2021

Abstract
A maxillary transverse deficiency is a common craniofacial problem. Rapid palatal expansion (RPE) has been traditionally considered for the treatment of children and young adolescents, but this is not applicable in late adolescents or adults due to the ossification of facial sutures. A surgically assisted rapid palatal expansion (SARPE) was initially advocated for this group of patients, but the surgical procedure is associated with morbidity. As temporary anchorage devices (TADs) have been recently and popularly applied in clinical orthodontics, micro-implant-assisted rapid palatal expansion (MARPE) has been employed to facilitate maxillary expansion in skeletally mature patients. There have been various proposed MARPE designs and the outcomes appear promising. The aim of the present article is to discuss the role of MARPE in clinical orthodontics by reviewing its background, design, indications, treatment effects, stability, and limitations in the current literature. The treatment effects of two types of MARPE, bone-borne and tooth-bone-borne (hybrid), will be individually assessed.
Quantitative assessment of interproximal tooth reduction performed as part of Invisalign® treatment in 10 orthodontic practices
Authors: Weir Tony , Shailendran Arun , Kerr Brett , Freer Elissa 
Published: October 2021

Abstract

Background
Interproximal reduction (IPR) is a treatment option for orthodontic space gain. The attainment of prescribed objectives in aligner treatment may require IPR that is accurately performed both qualitatively and quantitatively.

Objective
This study assesses the in vivo accuracy of IPR carried out in 10 orthodontic practices as a method of orthodontic space creation.

Methods
A comparison of proposed and achieved amounts of IPR completed (accuracy), the accuracy of IPR within and between upper and lower dental arches, and the accuracy of IPR within and between posterior and anterior arch segments were performed using 3-dimensional digital study models gained via Align’s® ClinCheck.

Results
The findings indicated that IPR was routinely underperformed by all practices studied. On average, the amount of IPR achieved represented only 44.0% of the total prescribed per tooth in the sample assessed, with a mean discrepancy of 0.16 mm per tooth. There were statistically significant differences only between the overall anterior and posterior groups (p < 0.01) and between maxillary anterior and maxillary posterior groups (p < 0.01); however, these were not clinically significant. Significant differences in IPR performance were noted between different orthodontic practices.

Conclusions
This study demonstrates that the clinical performance of IPR in 10 orthodontic practices consistently fails to achieve the prescribed amount often by large variations. The effect of this under-performance on clinical outcomes remains to be quantified.
Memperkaya Pemahaman Alkitab dengan Perspektif Kepercayaan Lain: Interpretasi Sosio-Retorik Roma 2:12–16
Authors: Surbakti Pelita Hati 
Published: October 2021

AbstractTaking account of contexts in hermeneutics and further theological works is interesting. Archie C.C. Lee, when developing cross-textual hermeneutics, stated that the knowledge about context could enrich the understanding of the biblical text. For him, this proposition also applies if the context is a cultural-belief outside Christianity. The reason is because God is the God of history, so that God is and continues to work in all human civilizations, including in cultural-beliefs that are often considered pagans. However, reasoning derived from biblical texts is rarely proposed. This article proposes Romans 2:12–16 as an alternative reasoning, using socio-rhetorical interpretation method. Inthis text Paul states that those who are referred to as “those who do not have the Law” (gentiles) actually have the Torah written in their hearts and materialize it in deeds. The finding of this study confi rms Lee’s argument.
AbstrakMempertimbangkan konteks dalam berhermeneutika dan selanjutnya berteologi kian menarik. Archie C.C. Lee, ketika mengembangkan hermeneutika lintas-tekstual, menyatakan bahwa dengan memper-timbangkan konteks bahkan dapat memperkaya pemahaman terhadap teks Alkitab. Bagi dia, dalil ini juga berlaku bila konteksnya adalah kebudayaan-kepercayaan di luar kekristenan. Alasannya adalah karena Allah merupakan Allah atas sejarah, maka Ia juga telah dan terus berkarya dalam seluruh peradaban manusia, termasuk dalam kebudayaan-kepercayaan yang kerap dinilai kafir. Namun, alasan yang bersumber dari teks Alkitab jarang diusulkan. Melalui tulisan ini saya mengusulkan Roma 2:12–16 sebagai alternatif alasan. Interpretasi sosio-retorik akan digunakan untuk menafsir teks ini. Melalui teks ini Paulus menyatakan bahwa orang yang disebut sebagai “orang-orang yang tidak memiliki Taurat” (kafir) sekalipun ternyata memiliki Taurat yang tertulis dalam hatinya, dan mereka bahkan mampu melakukannya. Temuan kajian ini menegaskan pandangan Lee.