bluuebunny/crossref_metadata_2025_split huggingface dataset:
Uncomplicated crown fracture management
Authors: Siddiqua Niher Tabassum , Karim Fahd AA , Rahman Md Toufiqur , Mamun Abdullah Al 
Published: April 2021

Background: Trauma-related injuries of the maxillofacial region occur more often these days and dentists are facing this condition frequently in their regular practice life. Traumatic dental injuries affects the same region with different frequencies in different age groups. It should be noted that upper central incisors are mostly traumatized by injuries compare to the other incisors. The maxillary central incisors were about 72%, while premolars, canine, mandibular incisors, the upper lateral incisors injury rate is up to 8%. A strong impact most often affects the crown and a weak and dull impact on the root apical direction and may result in avulsion of tooth and root fracture. Dental injuries caused by trauma have been an emergency condition, treatment options depend on the severity of injuries and clinical condition of the tooth at that moment. Combination treatment for a traumatic fracture of the tooth includes fixation of the tooth, the performance of surgical manipulation, determination of the need for endodontic treatment, restoration, and orthodontic consultations.
Problem: In our case patient has an uncomplicated crown fracture.
Solution: Direct composite restoration.
Update Dent. Coll. j: 2021; 11 (1): 20-22
Penerapan Metode SMA Untuk Peramalan Tingkat Produksi Tanaman Pangan di Dinas Pertanian
Authors: Sitorus Novita Sari , Siagian Yessica , Aulia Romy 
Published: April 2021

Abstract: Food is the most important foodstuff needed by humans, in addition to consumption, the production of food crops can also be used as a source of business in the economy. This study aims to predict the production of food crops in the Agriculture Office of Asahan Regency. Based on data on food crop production from 2012 to 2019 at the Asahan District Agriculture Office experienced ups and downs, food crop production sometimes does not meet the consumption of people in Asahan Regency (devisit) and sometimes overproduction (surplus). So far, the Agriculture Office of Asahan Regency has predicted the production of food crops only with estimates so that the results are not accurate. Based on these problems, a proper forecasting system is needed so that it is able to predict the production rate of food crops quickly and accurately. Applications are built using Visual Basic Net 2010 and MySQL databases and use the Single Moving Average method. The results of this study can help the Agriculture Office of Asahan Regency in predicting the amount of food crop production in the next period according to the needs. Keywords : Forecasting, Production, Food Crops, Single Moving Average Abstrak: Pangan merupakan bahan makanan paling utama yang di butuhkan oleh manusia, selain untuk dikomsumsi, hasil produksi dari tanamana pangan juga dapat dijadikan sebagai sumber usaha dalam perekonomian. Penelitian ini bertujuan untuk melakukan prediksi produksi tanaman pangan pada Dinas Pertanian Kabupaten Asahan. Berdasarkan data produksi tanaman pangan dari tahun 2012 sampai dengan tahun 2019 pada Dinas Pertanian Kabupaten Asahan mengalami naik turun, produksi tanaman pangan terkadang tidak memenuhi konsumsi masyarakat di Kabupaten Asahan (devisit) dan terkadang kelebihan produksi (surplus). Selama ini Dinas Pertanian Kabupaten Asahan melakukan prediksi produksi tanaman pangan hanya dengan perkiraaan-perkiraan saja sehingga hasilnya tidak akurat. Berdasarkan permasalahan tersebut maka dibutuhkan sistem peramalan yang tepat sehingga mampu meramalkan tingkat produksi tanaman pangan dengan cepat dan akurat. Aplikasi dibangun menggunakan Visual Basic Net 2010 dan database MySQL serta menggunakan metode Single Moving Average. Hasil dari penelitian ini dapat membantu Dinas Pertanian Kabupaten Asahan dalam memprediksi jumlah produksi tanaman pangan pada periode berikutnya sesuai dengan kebutuhan. Kata Kunci : Peramalan, Produksi, Tanaman Pangan, Single Moving Average
Penerapan Model Scrum dalam Perancangan Sistem Informasi Penelitian dan Pengabdian Kepada Masyarakat
Authors: Kurniawan Edi , Imtihan Khairul , Tantoni Ahmad 
Published: April 2021

Abstract:Application of the Scrum model in the design of research and community service information systems (Case study at STMIK Lombok), the Institute for Research and Community Service (LPPM) is an activity unit that functions to manage all research and community service activities carried out by lecturers in connection with the lecturer improving the quality of the lecturer. The formulation of the problem is how to design and build a research and community service information system so as to facilitate the process of submitting proposals, accepting, selecting, reviewing, approving, controlling implementation and facilitating reporting. This study uses data collection methods namely observation and interviews, while the system development method uses the Scrum method, the following is a description of the stages of software development using the Scrum method, namely: Produck Backlog, Sprint Backlog, Sprint and Working Increment of the Software. Based on the data analysis, it was concluded that the research and community service information system was designed to facilitate the submission of research proposals as well as the dedication and reporting of research and service activities being carried out by lecturers. Presentation of information in this system includes lecturer data input, input of research proposal, dedication proposal input, print decision letter and report data input. Keywords:Information Systems Research and Community Service, SCRUM Method Abstrak:Penerapan model Scrum dalam perancangan sistem informasi penelititan dan pengabdian kepada masyarakat (Studi kasus di STMIK Lombok), Lembaga Penelititan dan Pengabdian pada Masyarakat (LPPM) adalah sebuah unit kegiatan yang berfungsi mengelola semua kegiatan penelititan dan pengabdian kepada masyarakat yang dilakasanakan oleh dosen dalam kaitan dengan peningkatan kualitas dosen tersebut. Adapun perumusan masalahnya bagaimana merancang dan membangun sistem informasi penelitian dan pengabdian kepada masyarakat sehingga mempermudah dalam proses pengajuan proposal, penerimaan, seleksi, review, persetujuan, pengontrolan pelaksanaan dan mempermudah pelaporan. metode pengembangan sistemnnya menggunakan metode Scrum, uraian dari tahap-tahap pengembangan perangkat lunak menggunakan metode Scrum yaitu : Produck Backlog, Sprint Backlog, Sprint dan Working Increment Of The Software. Berdasarkan analisa data yang dilakukan diperoleh kesimpulan bahwa Sistem informasi penelitian dan pengabdian kepada masyarakat ini dirancang untuk melakukan kemudahan dalam pengajuan usulan proposal penelitian maupun pengabdian dan pelaporan kegiatan penelitian dan pengabdian yang sedang dilakukan oleh dosen. Penyajian informasi dalam sistem ini meliputi input data dosen, input proposal penelitian, input proposal pengabdian, mencetak surat keputusan dan input data laporan. Kata kunci:Sistem Informasi Penelitian dan Pengabdian kepada Masyarakat, Metode SCRUM.
Analisis Komoditas Padi Pascapanen Berbasis E-SCM Studi Kasus Kilang Padi Sumber Rezeki
Authors: Dewi Afrianti , Azhar Zulfi , Fauziah Rizky 
Published: April 2021

Abstrct : The object of this research is the Sumber Rezeki Rice Refinery which produces rice in Taman Sari, Kec.Pulo Bandring. This Rice Refinery in the processing of supply chain management that has been done can increase the amount of profit and market share by purchasing rice. Aspects of analysis that occur produce effectiveness and efficiency together in one flow cycle. The use of observations and discussions in the field and designing an application system so that it is able to cope with the rice supply that occurs and predict the rice stock that must be provided by the Sumber Rezeki Rice Refinery. Keywords: a source of sustenance; predictions; scm; application system; rice stock. Abstrak : Objek pada penelitian ini adalah pada Kilang Padi Sumber Rezeki yang berproduksi beras di Taman Sari, Kec.Pulo Bandring. Kilang Padi ini dalam pengolahan supply chain management yang telah dilakukannya dapat meningkatkan jumlah keuntungan dan pangsa pasar dengan melakukan pembelian beras. Aspek analisis yang terjadi menghasilkan keefektifan dan keefesienan bersama-sama dalam satu siklus aliran. Penggunaan observasi dan diskusi di lapangan serta melakukan perancangan sistem aplikasi sehingga mampu menanggulangi persediaan beras yang terjadi dan memprediksi stok beras yang harus disediakan oleh Kilang Padi Sumber Rezeki. Kata kunci : Kilang padi sumber rezeki; prediksi; scm; sistem aplikasi; stok beras.
Sistem Informasi Survei Penyusunan Disagregasi Pembentukan Modal Tetap Bruto (PMTB) Berbasis Web
Authors: Yudha Cris Karya , Tasril Virdyra , Putra Randi Rian 
Published: April 2021

Abstract: Susenas is one of the important household socio-economic data sources in Indonesia. Susenas has become the main reference for meeting the needs of the government in implementing national development so that it is in line with the National Medium Term Development Plan (RPJMN), nine priority agendas or nawacita and the goals of Sustainable Development. A survey is a method of collecting data by giving questions to respondents. a survey is the best way to get correct information and the results can be justified. In the process of collecting PMTB survey data, which is carried out by partner officers, it is still implementing a manual system where partner officers come to the company / business under the form to fill in the company's income and expenditure data, and then the partner returns to the ledger to be analyzed by the Balance Sheet officer, the author intends to create a web-based system that is considered to provide an effective solution and can be used as a tool for PMTB data collection using the interview research method and direct observation to the Medan City BPS office. Keywords: BPS (Badan Pusat Statistik), PMTB, Survei, User, Web Abstrak: Susenas merupakan salah satu sumber data sosial ekonomi rumah tangga yang penting diindonesia. Susenas telah menjadi rujukan utama untuk memenuhi kebutuhan pemerintah dalam mengimplementasikan pembangunan nasional agar sejalan dengan Rencana Pembangunan Jangka Menengah Nasional (RPJMN), sembilan agenda prioritas atau nawacita dan tujuan Pembangunan Berkelanjutan. Survei adalah metode pengumpulan data dengan memberikan pertanyaan – pertanyaan kepada responden. survei merupakan cara terbaik dalam mendapatkan sebuah informasi yang benar dan dapat dipertanggungjawabkan hasilnya. Dalam proses pengumpulan data survei PMTB yang dilakukan oleh petugas mitra masih menerapkan sistem manual yang mana petugas mitra datang ke perusahaan/usaha membawah formulir pengisian data pendapatan dan pengeluaran perusahaan, dan selanjutnya mitra kembali menulis ke buku besar untuk dapat di analisa oleh petugas Neraca, penulis bermaksud membuat suatu sistem berbasis web yang dipandang dapat memberikan solusi yang efektif serta dapat dijadikan sebagai alat pendataan PMTB dengan menggunakan metode penelitian wawancara dan observasi langsung ke kantor BPS Kota Medan. Kata kunci: BPS (Badan Pusat Statistik), PMTB, Survei, User, Web
Sistem Pendukung Keputusan Untuk Menentukan Sanksi Pelanggaran Siswa Menggunakan Metode TOPSIS
Authors: Sari Rita Ratna , Nurwati Nurwati , Rahayu Elly 
Published: April 2021

Abstract:All students in the world of education in the learning process are not separated from the various rules and regulations that apply or are implemented by the school and it is mandatory to be obeyed by every student. With this, it is intended that every student knows about discipline. At SMP Negeri 1 Bosar Maligas presence, tidiness, personality and order are aspects of discipline which are used as references to measure the level of student discipline. The mechanism for measuring the level of discipline of each student is measured manually, namely by accumulating points of violations committed by students, then determining the sanctions that will be given. The purpose of this study is to analyze and design a decision support system to determine the level of discipline and sanctions for student violations using the TOPSIS (Technique Order Preference by Similarity To Ideal Solution) method and implement the system to assist counseling teachers in monitoring student discipline levels, and can be effective and efficiently find the number of points of violation committed by students. The system is designed using the MySQL database, PHP programming language, and Macromedia Dreamweaver application software. Keywords: Discipline, TOPSIS, Macromedia Dreamweaver, Hypertext PrePocessor, Decision Support Systems. Abstrak: Semua siswa di dalam dunia pendidikan dalam proses belajar tidak ada yang terlepas dari berbagai tata tertib dan peraturan yang berlaku atau di jalankan oleh sekolah dan memang wajib harus di taati oleh setiap siswa. Dengan adanya hal tersebut bertujuan supaya setiap siswa mengetahui tentang kedisiplinan. Di SMP Negeri 1 Bosar Maligas kehadiran, kerapian, kepribadian dan ketertiban merupakan aspek kedisiplinan yang dijadikan sebagai acuan untuk mengukur tingkat kedisiplinan siswa. Mekanisme pengukuran tingkat disiplin dari masing-masing siswa diukur dengan cara manual, yaitu dengan mengakumulasi point pelanggaran yang dilakukan siswa, kemudian ditentukan sanksi yang akan diberikan. Tujuan dari penelitian ini untuk menganalisis dan merancang sistem pendukung keputusan untuk menentukan tingkat kedisiplinan dan sanksi pelanggaran siswa menggunakan metode TOPSIS (Technique Order Preferenceby Similarity ToIdeal Solution) dan mengimplementasikan sistem tersebut untuk membantu guru BK dalam memantau tingkat kedisiplinan siswa, dan dapat dengan efektif dan efesien mencari jumlah point pelanggaran yang di lakukan oleh siswa.Sistemdi rancang menggunakan database MySQL,bahasa pemrograman PHP, dan software aplikasi macromedia dreamweaver. Kata Kunci :Kedisiplinan, TOPSIS, Macromedia Dreamweaver, PHP, Sistem Pendukung Keputusan.
El arte urbano un museo al aire libre de nuestro patrimonio: el caso de Fuenlabrada como recorrido artístico.
Authors: López Méndez Lorena 
Published: April 2021

El arte urbano, a pesar de ser un fenómeno artístico que ha evolucionado exponencialmente en las últimas décadas, en ocasiones pasa desapercibido por los viandantes de una ciudad, pero en otras las pinturas murales son valoradas por el trasfondo social, cultural y político que transmiten; algunos mensajes tienen una intencionalidad por parte del autor de hacerse públicos, de llamar la atención y provocar al espectador. Como es el caso de los murales que pueden ser visitados en el municipio madrileño de Fuenlabrada. Murales que favorecen un recorrido artístico y participativo, como si se tratase de un museo al aire libre, pudiéndose considerar a día de hoy parte del paisaje urbanístico de la ciudad y por tanto parte de nuestro patrimonio cultural e inmaterial.
Expression of Lipid-Metabolism Genes Is Correlated With Immune Microenvironment and Predicts Prognosis in Osteosarcoma
Authors: Qian Hu , Lei Ting , Hu Yihe , Lei Pengfei 
Published: April 2021

ObjectivesOsteosarcoma was the most popular primary malignant tumor in children and adolescent, and the 5-year survival of osteosarcoma patients gained no substantial improvement over the past 35 years. This study aims to explore the role of lipid metabolism in the development and diagnosis of osteosarcoma.MethodsClinical information and corresponding RNA data of osteosarcoma patients were downloaded from TRGET and GEO databases. Consensus clustering was performed to identify new molecular subgroups. ESTIMATE, TIMER and ssGSEA analyses were applied to determinate the tumor immune microenvironment (TIME) and immune status of the identified subgroups. Functional analyses including GO, KEGG, GSVA and GSEA analyses were conducted to elucidate the underlying mechanisms. Prognostic risk model was constructed using LASSO algorithm and multivariate Cox regression analysis.ResultsTwo molecular subgroups with significantly different survival were identified. Better prognosis was associated with high immune score, low tumor purity, high abundance of immune infiltrating cells and relatively high immune status. GO and KEGG analyses revealed that the DEGs between the two subgroups were mainly enriched in immune- and bone remodeling-associated pathways. GSVA and GSEA analyses indicated that, lipid catabolism downregulation and lipid hydroxylation upregulation may impede the bone remodeling and development of immune system. Risk model based on lipid metabolism related genes (LMRGs) showed potent potential for survival prediction in osteosarcoma. Nomogram integrating risk model and clinical characteristics could predict the prognosis of osteosarcoma patients accurately.ConclusionExpression of lipid-metabolism genes is correlated with immune microenvironment of osteosarcoma patients and could be applied to predict the prognosis of in osteosarcoma accurately.
Deletion of the ATP2 Gene in Candida albicans Blocks Its Escape From Macrophage Clearance
Authors: Zhang Yishan , Tang Chuanyan , Zhang Zhanpeng , Li Shuixiu , Zhao Yajing , Weng Luobei , Zhang Hong 
Published: April 2021

Macrophages provide the first-line defense against invasive fungal infections and, therefore, escape from macrophage becomes the basis for the establishment ofCandida albicansinvasive infection. Here, we found that deletion ofATP2(atp2Δ/Δ) inC. albicansresulted in a dramatic decrease from 69.2% (WT) to 1.2% in the escape ratein vitro. The effect ofATP2on macrophage clearance stands out among the genes currently known to affect clearance. In the normal mice, theatp2Δ/Δ cells were undetectable in major organs 72 h after systemic infection, while WT cells persistedin vivo. However, in the macrophage-depleted mice,atp2Δ/Δ could persist for 72 h at an amount comparable to that at 24 h. Regarding the mechanism, WT cells sustained growth and switched to hyphal form, which was more conducive to escape from macrophages, in media that mimic the glucose-deficient environment in macrophages. In contrast,atp2Δ/Δ cells can remained viable but were unable to complete morphogenesis in these media, resulting in them being trapped within macrophages in the yeast form. Meanwhile,atp2Δ/Δ cells were killed by oxidative stress in alternative carbon sources by 2- to 3-fold more than WT cells. Taken together,ATP2deletion preventsC. albicansfrom escaping macrophage clearance, and thereforeATP2has a functional basis as a drug target that interferes with macrophage clearance.
Human Cytomegalovirus Genome Diversity in Longitudinally Collected Breast Milk Samples
Authors: Götting Jasper , Lazar Katrin , Suárez Nicolás M. , Steinbrück Lars , Rabe Tabea , Goelz Rangmar , Schulz Thomas F. , Davison Andrew J. , Hamprecht Klaus , Ganzenmueller Tina 
Published: April 2021

Reactivation and shedding of human cytomegalovirus (HCMV) in breast milk during lactation is highly frequent in HCMV-seropositive mothers. This represents a key transmission route for postnatal HCMV infection and can lead to severe disease in preterm neonates. Little is known about HCMV strain composition or longitudinal intrahost viral population dynamics in breast milk from immunocompetent women. We performed HCMV-specific target enrichment and high-throughput sequencing of 38 breast milk samples obtained in Germany between days 10 and 60 postpartum from 15 mothers with HCMV DNA lactia, and assembled HCMV consensus sequences de novo. The genotype distribution and number of HCMV strains present in each sample were determined by quantifying genotype-specific sequence motifs in 12 hypervariable viral genes, revealing a wide range of genotypes (82/109) for these genes in the cohort and a unique, longitudinally stable strain composition in each mother. Reactivation of up to three distinct HCMV strains was detected in 8/15 of mothers, indicating that a representative subset of the woman’s HCMV reservoir might be locally reactivated early during lactation. As described previously, nucleotide diversity of samples with multiple strains was much higher than that of samples with single strains. Breast milk as a main source of postnatal mother-to-infant transmission may serve as a repository for viral diversity and thus play an essential role in the natural epidemiology of HCMV.
Association Between Sex-Specific Serum Gamma-Glutamyltransferase and Incidence of Hypertension in a Chinese Population Without Metabolic Syndrome: A Prospective Observational Study
Authors: Wu Xiaoyun , Liang Dongjie , Sun Junfang , Lin Yanyan , Wu Shengjie 
Published: April 2021

Background: Higher serum gamma-glutamyltransferase (GGT) is associated with high risk of hypertension. We aimed to examine the association between sex-specific serum GGT levels and incident of hypertension in a Chinese population without metabolic syndrome.Methods: Participants who were free of hypertension and metabolic syndrome from the First Affiliated Hospital of Wenzhou Medical University between 2009 and 2014 were included. Participants were grouped into sex-specific quartiles of GGT levels (Q1–Q4) defined as: ≤19, 20–26, 27–38, and ≥39 U/L for male; ≤12, 13–15, 16–19, and ≥20 U/L for female. Cox proportional hazards models were used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for incidence of hypertension according to sex-specific quartiles of GGT levels. Kaplan–Meier analysis and interaction analysis were conducted.Results: Among 38,806 participants included (average age 36.0 years, 54.0% men), 4,505 of them developed hypertension. In the overall study population, using Q1 as the reference group, participants in Q2, Q3, and Q4 showed a higher risk of developing hypertension, with HRs (95% CIs) of 1.126 (1.029–1.232), 1.187 (1.083–1.302), and 1.300 (1.182–1.431), respectively (P &lt; 0.001), after adjusting for known confounders. Sex-specific analysis showed that the adjusted HRs for participants in Q4 (reference: Q1) were greater in females [1.321 (1.100–1.586, P &lt; 0.001)] than in males [1.268 (1.133–1.420, P &lt; 0.001)] (P for interaction = 0.047). Moreover, interaction analysis showed that this association was consistently observed when the participants were stratified by age, body mass index, and fatty liver status.Conclusion: Among Chinese adults without metabolic syndrome, serum GGT level was positively associated with incidence of hypertension, and the association was stronger in females than in males.