bluuebunny/crossref_metadata_2025_split huggingface dataset:
SINDROM TOLOSA HUNT DENGAN KETERLIBATAN SARAF OPTIKUS
Authors: Simanungkalit Astra Dea , Susyono Maria Larasati , Puspitasari Vivien 
Published: April 2021

TOLOSA HUNT SYNDROME WITH OPTIC NERVE INVOLVEMENTABSTRACTTolosa Hunt syndrome (THS) is a very rare clinical syndrome, which is characterized by unilateral headaches accompanied by dysfunction and painful ophthalmic nerves. In some cases, optic nerve involvement can be found due to inflammation at the orbital apex. Corticosteroid administration is a management of THS with pain relief generally occurring in the first 72 hours. However, corticosteroid administration is not significantly associated with nerve dysfunction or visual acuity improvement.This article is a case report of women with STH and optic nerve involvement.Keywords: Tolosa Hunt syndrome, painful ophtalmoplegia, orbital apex, superior orbital fissureABSTRAKSindrom Tolosa Hunt (STH) adalah sindrom klinik yang sangat jarang, yang ditandai oleh nyeri kepala unilateral disertai disfungsi dan nyeri saraf penggerak bola mata (painful ophtamloplegia). Pada beberapa kasus, dapat ditemukan keterlibatan saraf optikus akibat inflamasi pada apeks orbita. Pemberian kortikosteroid merupakan tatalaksana STH dengan perbaikan nyeri umumnya terjadi pada 72 jam pertama. Meskipun demikian pemberian kortikosteroid tidak berhubungan secara signifikan dengan perbaikan disfungsi saraf penggerak bola mata maupun tajam penglihatan. Artikel ini merupakan laporan kasus perempuan dengan STH dan keterlibatan saraf optikus.Kata kunci: Sindrom Tolosa Hunt, painful ophtalmoplegia, apeksorbita, fisura orbitalis superior
PENYAKIT CHARCOT MARIE TOOTH ONSET LANJUT
Authors: Merryn Kenny , Sabirin Jimmi , Octaviani Octaviani 
Published: April 2021

LATE ONSET CHARCOT MARIE TOOTH DISEASEABSTRACTCharcot Marie Tooth’s disease (CMT) is a hereditary sensoric motoric polineuropathy. Late onset CMT are rare reported in Indonesia. A woman 48 years old has numbness in her both arm and leg gradually since 5 years ago, followed by deformities and weakness. Her cousin has the same disease. In physical examination, there were flaccid type tetraparesis, socks and gloves hypesthesia, steppage gait, pes cavus, hammer toes, thenar, hypothenar, and extensor hallucis longus muscle atrophy bilaterally. Electrophysiology studies showed mixed sensoric and motoric polineuropathy with symetrically demyelinating and uniform slowing. Management were ascorbic acid, neurotrophic, physiotherapy, and occupational therapy.Keywords: Charcot Marie Tooth, hammer toes, pes cavus, steppage gaitABSTRAKPenyakitCharcot Marie Tooth (CMT) merupakan polineuropati motorik dan sensorik herediter. Kasus CMT onset lanjut di Indonesia masih sangat jarang dilaporkan. Seorang wanita 48 tahun mengalami kesemutan pada kedua lengan dan tungkai sejak 5 tahun secara perlahan diikuti perubahan bentuk tangan dan kaki serta kelemahan. Riwayat sepupu mengalami keluhan serupa. Pemeriksaan fisik didapatkan kelemahan kedua lengan dan tungkai tipe flaksid, hipestesi pola sarung tangan dan kaos kaki, steppage gait, pes cavus, hammer toes, atrofi otot tenar, hipotenar, dan ekstensor halusis longus bilateral. Pemeriksaan elektrofisiologi didapatkan polineuropati motorik sensorik dengan demielinisasi simetris dan perlambatan kecepatan konduksi seragam. Tata laksana pasien ini menggunakan asam askorbat, neurotropik, fisioterapi, dan terapi okupasi.Kata kunci: Charcot Marie Tooth, hammer toes, pes cavus, steppage gait
KARAKTERISTIK METASTASIS SISTEM SARAF PUSAT DARI KANKER PARU
Authors: Yosephine Tan , Aninditha Tiara , Riyanto Sofyan Henry , Odilo Jonathan , Andriani Rini 
Published: April 2021

Pendahuluan: Sebanyak 40% pasien dengan kanker paru akan mengalami metastasis sistem saraf pusat (SSP) dalam perjalanan penyakitnya. Dari 40% tersebut, sebanyak 3-9% akan mengalami metastasis leptomeningeal, namun profil klinis keterlibatan SSP pada kanker paru belum pernah diteliti di Indonesia.
Tujuan: Mengetahui gambaran metastasis SSP kanker paru di RSUPN Dr. Cipto Mangunkusumo (RSCM) dan RS Kanker Dharmais (RSKD).
Metode: Penelitian potong lintang terhadap pasien kanker paru yang dikonsulkan ke bagian Neurologi di RSCM dan RSKD sepanjang tahun 2018. Kriteria inklusi adalah pasien dewasa yang sudah terdiagnosis sebagai kanker paru berdasarkan pemeriksaan histopatologi dan memiliki data rekam medis lengkap, hingga gambaran CT scan atau MRI kepala dengan kontras.
Hasil: Didapatkan 48 subjek dengan median 57 (36-76) tahun, proporsi laki-laki lebih banyak dari pada perempuan (56,2% vs 44,8%) dan 31,3% mempunyai riwayat merokok. Jenis tumor paru tersering adalah kanker paru karsinoma bukan sel kecil (KPKBSK) atau non-small cell lung carcinoma (SCLC) (93,8%). Gejala neurologis terutama defisit motorik (62,5%), nyeri kepala (43,8%), gangguan fungsi luhur (20,8%), dan kejang (18,8%). Mayoritas subjek mengalami metastasis di otak (93,8%) dan sebanyak 8,3% di leptomeningeal.
Diskusi: Didapatkan tumor otak akibat metastasis dari kanker paru dengan jenis KPKBSK (93,8%) dengan gejala neurologis utama defisit motorik (62,5%) dan nyeri kepala (43,8%).

Kata kunci: Kankerparu, karsinoma sel kecil, metastasis otak.
JEZIČKI RAZVOJ
Authors: Nesimović Nejra 
Published: April 2021

Jezik je najsavršeniji sistem znakova pomoću kojega se izražavaju ideje, saopćavaju i prenose misli, želje i osjećaji, i socijalna je pojava. Tumačenja o nastajanju jezika i govora dale su brojne teorije i psiholingvističke škole, ali kako bismo dobili što kompletniju sliku, moramo biti eklektični, tj. trebamo sagledati i analizirati više pristupa i napraviti sintezu. Priroda je osigurala urođenu sposobnost za usvajanje jezika, ali bez socijalnog okruženja i stimulacije te kognitivnog razvoja, govor ne bi mogao biti usvojen. Razvoj govora nije prepušten slučaju, već prati određen pravac: u dobi od šest mjeseci djeca guču, javlja se slogovanje; u dobi od od osam mjeseci djeca savladavaju neka osnovna pravila govora; između 10. i 12. mjeseca izgovore svoju prvu riječ, a nakon toga se fond riječi brzo povećava, da bi u dobi do 18. mjeseca većina djece aktivno vladala rječnikom od oko 50 riječi koje izgovaraju, i oko 100 riječi koje razumiju. Između 6. i 12. godine jezički razvoj je stabilniji i mirniji od jezičke eksplozije tokom predškolskog perioda. Neophodno je komunicirati s djecom već od samoga rođenja. U protivnom će mozak djeteta biti „paraliziran“ na jezičke stimuluse i na generiranje riječi. Kao dokaz mnogi istraživači navode slučajeve „divlje djece“, kojima je jezička stimulacija bila uskraćena, posebno tokom kritičnog perioda za usvajanje govora. Bez obzira što su djeca bila fizički zdrava, nisu bila u stanju da kasnije sastave niti jednu najprostiju rečenicu. Zanimljivo je napomenuti i na postojanje još jednog vida govora, koji je u službi razvoja jezika. To je unutrašnji govor koji se javlja između 3 i 4 godine, a iščezava polaskom djeteta u školu. Manifestira se kao glasni govor koji nije upućen sagovornicima, nego predstavlja prijelaznu fazu govora kao sredstva komunikacije u govor kao govor mišljenja. Drugi naziv koji se upotrebljava za ovaj govor je egocentrični govor, a veliki doprinos u izučavanju i razumijevanju njegove svrhe dali su Vigotsky i Piaget.
LIJEČNIČKE GREŠKE / POGREŠKE - DEFINICIJE, UZROCI I ODGOVORNOSTI LIJEČNIKA
Authors: Kendić Sulejman , Salihagić Adem 
Published: April 2021

Predmet medicinske/zdravstvene djelatnosti jeste očuvanje, zaštita života i unapređenje zdravlja pojedinaca i društva kao temeljnih vrijednosti. Od medicinske profesije se zahtijeva da se kao životno usmjerenje prihvati prosvjećenosti zaštiti ljudskog zdravlja, da se poštuje ljudski život, ljudske vrijednosti i dostojanstvo, da se uvijek u prvi plan stavlja dobrobit pacijenta, da se svjesno preuzima odgovornost za pacijenta, da se pomoć pruža uvijek jednako svima i po savjesti. Štete koje nastanu u obavljanju ove djelatnosti čine se posebno značajnim i pitanje odgovornosti je posebno osjetljivo. Medicinska djelatnost osim što je regulirana pravilima struke, bila je regulirana oduvijek etičkim normama, a tek periferno pravnim pravilima. Doktor-pacijent je do sredine XX vijeka bio reguliran više moralnim nego pravnim normama, dok se danas situacija značajno izmijenila. Medicina kao nauka i kao praksa doživljava brzi naučni i tehnološki napredak. Povećava se broj intervencija i zdravstvenih usluga. Zahtjevi korisnika su složeniji, intervencije ofenzivnije, gdje se uključuje veliki broj različitih stručnjaka u sistem zaštite, a time i rastu veće mogućnosti za nastanak grešaka i nanošenja štete pacijentu.
ÉMILE BENVENISTE: “O HOMEM NA LÍNGUA” ENTRE A LINGUÍSTICA, LITERATURA E A ANTROPOLOGIA – UMA REVISÃO INTEGRATIVA EM PESQUISAS NA PÓS-GRADUAÇÃO DO BRASIL
Authors: LIMA Lilian Castelo Branco de , ASSIS Emanoel César Pires de , ALMEIDA Wemylla De Jesus 
Published: April 2021

Este trabalho se dedica a fazer uma revisão integrativa da literatura em dissertações e teses que abordem as ideias de Émile Benveniste e identificar a quais programas de pós-graduação no Brasil elas são vinculadas. Com o objetivo de investigar a incidência com que as obras do autor serviram de fundamentação para as análises desenvolvidas por pesquisadores brasileiros e os diálogos estabelecidos para dar suporte aos estudos dos objetos de pesquisa. Para isso, utilizou-se dois bancos de dados: Catálogo de Teses e Dissertações da Capes e a Biblioteca Digital Brasileira de Teses e Dissertações.
Ex(s) Paços críticos: Memória e diálogos de uma exposição online
Authors: Arantes Priscila Cunha Almeida , Bastos Marcus 
Published: April 2021

Com a pandemia do COVID-19, o ambiente online se tornou um espaço sem precedentes de difusão de arte e cultura. Claro que os formatos usados não são inéditos. Muitas vezes, eles nem são tão interessantes quanto experiências anteriores feitas com o intuito de explorar as possibilidades da cultura em rede, conforme ela se constitui. Por este motivo, o foco deste artigo é voltado para práticas menos convencionais que se desenvolvem no ambiente da arte contemporânea, especialmente nas linguagens de acontecimentos efêmeros (um campo variado que abrange de poesia sonora e performance às artes da transmissão e mídias locativas). Visando discutir estas questões o presente artigo investiga o projeto curatorial Ex(s)paços Críticos, desenvolvido no ambiente virtual junto ao Paço das Artes, bem como produções e sites que arquivam e circulam a arte na rede . Palavras chaves: curadoria; arte em rede; Paço das Artes; arte contemporânea.
La rose de Notre-Dame de Noyon et sa place dans la technique et le décor du troisième chantier de la cathédrale
Authors: Hardy Chantal 
Published: April 2021

The rose-window has been very important in the development of fenestrage major elements in Gothic architecture. The earliest examples appear in the middle of the twelfth century on the Île-de-France and are not well-known, particularly those with free-standing colonnettes, a type which Viollet-le-Duc does not include in what is still the basic work of reference for the rose-window. There is a very old window of this type preserved in the cathedral of Noyon. A careful study reveals the importance of the form within the third campaign of the cathedral, ca. 1170-1185. After establishing its authenticity and general date, a detailed analysis places the window within the building, from the point of view of both technique and decoration. Three types of circular window were constructed during the course of this campaign. The rose-window of the Treasury shows the same type of insertion under the vault as the small polylobed oculus at the lower side, north of the nave (1170). The tracery of the rose-window is made of stone slabs cut into cusped voussoirs and of colonnettes en délit, both elements found from the beginning to the end of the campaign. The Treasury rose-window has a rare feature: a primitive method for securing the frame. The armature is fastened to the interior surface of the curved wedges leaving the colonnettes of the tracery free. This system seems to explain the presence of bilobed arches at the border of the frame, an innovation for the rose-window with colonnettes. The decoration of the rose-window is linked to the secondary decoration of the portal of the annex of the north arm of the transept, under the rose-window, as well as to the very ornate high part of the choir. The execution of the rose-window can be dated between these points, ca. 1170-1175. The archivolt of the rose-window includes the mascaron, a very important motif in the decoration of the cathedral of Noyon and also associated with the earliest rose-windows (Saint-Denis, ca. 1140). The workshop of Noyon is an important center in the development of Gothic architecture, particularly for the treatment of its windows grouped by pairs in the double walls system of the transept or composed with an oculus over twin lancets in the Bishop’s chapel. This last formula is recognized as the most direct source for the composition of the high windows of the nave of Chartres cathedral. However at Chartres the rose-window hollows out the entire wall beneath the formeret or the vault, often considered an original creation of the Master of Chartres. This type of piercing, however, was also used in the workshop of Noyon for the rose-window of the Treasury. The study of that rose-window accentuates, through this fact, the importance of the workshop in the development of the large elaborate gothic window.
La primitiva decorazione pittorica del portico di S. Lorenzo fuori le mura : osservazioni sulla tecnica
Authors: Basile Giuseppe 
Published: April 2021

The recent restoration of the earliest pictorial decoration of the portico of S. Lorenzo fuori le mura, executed under the author’s direction, provided the occasion for the reconsideration of a wide range of technical issues relating to the manufacture of the mediaeval frescoes there. Careful analysis of the technique used reveals new aspects of their making. The cycles, which date to the decade 1216-26 and the pontificate of Honorius iii, were restored according to one of the two preferred methods that were available and explanation is provided for this choice.
Roma e Montecassino : gli affreschi della chiesa inferiore di S. Crisogono
Authors: Brenk Beat 
Published: April 2021

Attention is focused on mediaeval frescoes in the lower church of San Crisogono (surviving in part), which have not systematically been examined before. Questions such as the probable date of execution, the identity of the commissioner and the significance of the decoration are asked and answered. The usual dating of the decoration to the 10th century is, on the basis of new stylistic and iconographic evidence, shifted to the 11th century and more specifically after 1041 when the legend of Saint Benedict received visual expression in the Abbey of Montecassino. This decorative cycle appears to be a key in unlocking the dating of the cycle in S. Crisogono, in providing an iconographic model for the depiction of the various scenes, and quite possible in offering not only a stylistic reference point but also in providing the patron of the Roman frescoes. It is proposed that the patron was the abate Federico da Montecassino, who was also cardinal of S. Crisogono and for a short time before his death in 1057, Pope Stefanius ix. If this suggestion is appropriate, then new information can be obtained from the cycle regarding 11th-century mural decoration and the importance of S. Crisogono in the development of this tradition.
Lawren Harris and the International Exhibition of Modern Art
Authors: Pfaff L. R. 
Published: April 2021

En 1927, du 1er au 24 avril, l’Exposition internationale d’art moderne, provenant de la collection de la Société Anonyme de New York, fut présentée par l’Art Gallery of Ontario à Toronto. Le Comité des expositions qui avait d’abord résolu de ne pas participer à cet événement jugé « trop révolutionnaire » dut cependant revenir sur sa décision par suite des pressions de Lawren Harris, éminent artiste de Toronto. Dans une lettre datée du 26 décembre et reproduite ici en entier pour la première fois, Harris s’engageait à faire venir à ses frais l’exposition, si le comité maintenait son attitude. Mais la lettre atteignit son but et le Canada connut sa première exposition d’art abstrait, événement comparable en importance à ce qu’avait été l’Armory Show aux États-Unis. Le catalogue imprimé alors, considéré jusqu’à présent comme un document fidèle de l’exposition tenue à Toronto, se révèle à plus d’un titre trompeur et erroné. En effet, la découverte récente d’une copie de ce catalogue annotée par E.R. Greig, conservateur de l’Art Gallery of Toronto en 1927, permet de constater pas moins de 25 corrections apportées à la liste des oeuvres, Greig ayant indiqué les oeuvres qui, bien qu’annoncées, ne furent, pas accrochées ou installées. Cette liste de la publication de 1927 est redonnée ici avec les annotations de Greig. L’exposition qui fit sensation à Toronto attira plus de 10 000 personnes, nombre peu ordinaire pour cette époque. Dans les journaux locaux, on trouve presque quatre fois plus de comptes rendus de cette exposition, par rapport aux autres expositions spéciales présentées par l’Art Gallery. Les commentaires critiques des journalistes ou d’artistes s’exprimant dans les journaux et les périodiques contenaient des prises de positions énergiques en faveur ou contre l’exposition. Quatre de ces articles sont présentés en annexe.
Um necessário passo para trás: notas para fundamentação de uma hermenêutica do feminino a partir de sua relação com a psicologia
Authors: Chohfi Laiz 
Published: April 2021

Este artigo busca contribuir para a fundamentação de uma hermenêutica do feminino desde a perspectiva da psicologia à luz da fenomenologia hermenêutica. Para tanto apresenta-se, partindo de levantamento bibliográfico de artigos publicados ao longo da última década, o modo próprio de conduzir investigações desta abordagem, que é das grandes escolas de psicologia brasileira. Configuram características desse pesquisar a precisão no enfoque que se dá às obras filosóficas lidas, o debruçar-se sobre fenômenos concretos, mesmo para estudos teóricos, a não-pretensão de construção de verdades absolutas e, por último, a importância para o perguntar. Na sequência, apresenta-se a situação hermenêutica heideggeriana enquanto possível articulação metodológica de análise como fundamento possível para uma hermenêutica do feminino. A partir das coordenadas do ponto de vista, perspectiva e horizonte, componentes da noção de situação hermenêutica, é possível cuidar para não se sobrepor à visão daquela com quem se conversa em campo. Além disso, a partir da aplicação das coordenadas da situação hermenêutica é possível acompanhar processos de transformação naquelas com quem se troca em campo. Nesse sentido, conclui-se que a prática psicológica à luz da fenomenologia hermenêutica é fértil para o desenvolvimento de uma hermenêutica do feminino, oferecendo abertura e coordenadas que acompanham o mostrar-se da mulher e que não primam pela neutralização do que lhe é próprio.
Comparison of early season crop types for wheat production and nitrogen use efficiency in the Jianghan Plain in China
Authors: Yang Rui , Liu Ke , Geng Shiying , Zhang Chengxiang , Yin Lijun , Wang Xiaoyan 
Published: April 2021

The rice-wheat (RW) cropping system is one of the most prevalent double-cropping systems used to farm the Jianghan Plain in China. However, it can lead to low wheat yields and reduced nitrogen use efficiency compared with dryland wheat (DW). We evaluated wheat yield and nitrogen use efficiency for two rotations (summer rice-winter wheat and summer soybean-winter wheat) from 2017 to 2019 and applied the results to improve nitrogen management for planting wheat after rice in the Jianghan Plain. Field experiments were conducted over two years with two nitrogen treatments: traditional nitrogen management (M1: 90 kg N ha−1 was applied at sowing and jointing, respectively ) and optimized nitrogen management (M2: 60 kg N ha−1 was applied at sowing, wintering and jointing, respectively). The highest total wheat production was achieved under M2 for both cropping systems and the two-year average yield was 6,128 kg ha−1 in DW and 6,166 kg ha−1 in RW. The spike number in DW was 15% higher than RW in M1 and 13% higher in M2, but the kernel per spike and 1,000-grain weight was lower than RW. The nitrogen accumulation of DW was 24% higher than RW in M1 and 33% in M2. Compared with RW, DW had higher NO3− content in the soil surface layer (0–20 cm) and a higher root length density (RLD) in the deeper layer (40–60 cm), which may account for the higher N uptake in DW. Our results show that the grain yield of RW was comparable to that of DW by optimum nitrogen management. The rice-wheat cropping system combined with optimum nitrogen management may be of economic and agronomic benefit to the wheatbelt in the Jianghan Plain in China.
In vitro and In vivo Anticonvulsant Effect of Hydroalcoholic Extracts of Clutia abyssinica in Mice Model
Authors: Salile Samson Sahile , Abula Teferra 
Published: April 2021

Background: Epilepsy is a chronic disorder of the brain that affects people of all ages worldwide. In the search of safe and effective antiepileptics traditional treatment practices are one area of research to obtain novel molecules. Research is also needed to validate and standardize the traditional claim. Clutia abyssinica leaves were one of the medicinal plants claimed for use against epilepsy and evil eye and other diseases in different parts of Ethiopia. But there was no scientific research evidence for the claimed use of the plant. Therefore this work was designed to evaluate the anticonvulsant effect of hydroalcoholic extract of Clutia abyssinica leaves.
Methods: The dry residue of the plant extract was used for the test. In vitro 0Mg2+ mice model at dose 0.7 mg/kg of extract, diazepam (3μM) and untreated brain slice groups were used to compare the presence of seizure like event (SLE). In vivo pentylenetetrazol (PTZ) model with 85 mg/kg subcutaneously was used to compare the seizure onset time with two extract doses and diazepam 5 mg/kg. The data was presented with mean± standard error. In maximum electric shock (MES) model 54 mA was passed for 0.2 second transauricularly in mice. The mean time of hind limb extension was recorded for doses 400 mg/kg and 800mg/kg of the extract and 10 mg/kg phenytoin. The means were compared for statistical significance using one way ANOVA post hoc LSD whereas proportions were compared using Fishers exact test with P-value < .05.
Results: In vitro anticonvulsant tests C. abyssinica extract effect was not statistically significant compared to negative control (P>0.05).A positive control using the known anticonvulsant diazepam (3μM), showed significant anticonvulsant activity (P<0.05). The in vivo PTZ test showed no statistically significant effect in plant extract at all dose levels (P>0.05). In the in vivo MES test the extract of Clutia abyssinica both low and higher dose didn't show statistically significant effect (P>0.05) compared with the negative control. But the extract improved survival (p<0.05). The qualitative secondary metabolite test evidenced the presence of alkaloids, cardiac glycosides, flavanoids, phenols, saponins, sterols and terpeoids in Clutia abyssinica extract.
Conclusion: The hydroalcoholic crude extract result of the C. abyssinica as anticonvulsant is weak based on the models used in this study. For most of the local preparation are mixes of different plants it may have synergistic action with other plants. Or it may have action with other models of chronic epilepsy.