bluuebunny/crossref_metadata_2025_split huggingface dataset:
Polytriazole resins toughened by an azide-terminated polyhedral oligomeric silsesquioxane (OADTP)
Authors: Yu Zhuoer , Zhang Jun , Wu Bangqiang , Wan Liqiang , Huang Farong 
Published: April 2021

Abstract
An azido-terminated polyhedral oligomeric silsesquioxane (POSS) compound, octakis(azidopropyl-3-oxycarbonyl-1-decyl-10-thiopropyl-3-)POSS (OADTP), is synthesized and characterized. POSS-polytriazole (PTA) resins are prepared from an azide, an alkyne monomer, and OADTP. The toughening effect of OADTP on PTA resins is analyzed by impact performance test and electronic microscope characterization, and the thermal performance of resins is measured by thermogravimetric analysis and dynamic mechanical analysis. The results show that the addition of the POSS can improve the mechanical properties of PTA resins. The impact strength of POSS-PTA resins first increases and then decreases with the increase in the POSS compound, and the maximum one arrives at 54.8 kJ m−2 which increases by 44.2% as compared to 38 kJ m−2 of the PTA resin. A good thermal stability remains in POSS-PTA resins.
Is there an equality in the spatial distribution of urban vitality: A case study of Wuhan in China
Authors: Ou Guoliang , Zhou Min , Zeng Zhongping , He Qingsong , Yin Chaohui 
Published: April 2021

Abstract
Urban vitality is a spatial phenomenon and a public service. Previous studies often did not measure the fairness of the accessibility of urban vitality. This research analyzed the spatial distribution of urban vitality in Wuhan as a case study area using big data from multiple sources. The study used the two-step floating catchment area method (2SFCA) to measure the accessibility level of each residential district to the vibrant zones (VZs). Furthermore, the inequality in the level of accessibility of residential areas with different housing prices was assessed on the basis of the Gini coefficient. The main conclusions are as follows: (1) the Gini coefficient of reaching the accessibility level of high-grade VZs is 0.426, and the corresponding sub-high-grade Gini coefficient is 0.274. This shows that the inequality in accessibility of different residential areas is more obvious as the level of vitality is higher and (2) residential areas with high housing prices have greater accessibility than those areas with low housing prices. It was also noticed that the level of accessibility and fairness in vitality is generally higher in central urban areas than in suburban areas. The Gini coefficient of high-grade vitality is generally higher than that of sub-high-grade. The results of this study provide a reference for researching the accessibility level of urban vitality, which considers the needs of population, and can also provide guidelines in urban planning regarding the allocation of services and resources.
German oncology certification system for colorectal cancer – relative survival rates of a single certified centre vs. national and international registry data
Authors: Richter Maximilian , Sonnow Lena , Mehdizadeh-Shrifi Amir , Richter Axel , Koch Rainer , Zipprich Alexander 
Published: April 2021

Abstract

Objectives
To evaluate how the certification of specialised Oncology Centres in Germany affects the relative survival of patients with colorectal cancer (CRC) by means of national and international comparison.

Methods
Between 2007 and 2013, 675 patients with colorectal cancer, treated at the Hildesheim Hospital, an academic teaching hospital of the Hannover Medical School (MHH), were included. A follow-up of the entire patient group was performed until 2014. To obtain international data, a SEER-database search was done. The relative survival of 148,957 patients was compared to our data after 12, 36 and 60 months. For national survival data, we compared our rates with 41,988 patients of the Munich Cancer Registry (MCR).

Results
Relative survival at our institution tends to be higher in advanced tumour stages compared to national and international cancer registry data. Nationally we found only little variation in survival rates for low stages CRC (UICC I and II), colon, and rectal cancer. There were notable variations regarding relative survival rates for advanced CRC tumour stages (UICC IV). These variations were even more distinct for rectal cancer after 12, 36 and 60 months (Hildesheim Hospital: 89.9, 40.3, 30.1%; Munich Cancer Registry (MCR): 65.4, 28.7, 16.6%). The international comparison of CRC showed significantly higher relative survival rates for patients with advanced tumour stages after 12 months at our institution (77 vs. 54.9% for UICC IV; raw p<0.001).

Conclusions
Our findings suggest that patients with advanced tumour stages of CRC and especially rectal cancer benefit most from a multidisciplinary and guidelines-oriented treatment at Certified Oncology Centres. For a better evaluation of cancer treatment and improved national and international comparison, the creation of a centralised national cancer registry is necessary.
Quantifying the efficiency of written language
Authors: Koplenig Alexander 
Published: April 2021

Abstract
Information theory can be used to assess how efficiently a message is transmitted on the basis of different symbolic systems. In this paper, I estimate the information-theoretic efficiency of written language for parallel text data in more than 1000 different languages, both on the level of characters and on the level of words as information encoding units. The main results show that (i) the median efficiency is ∼29% on the character level and ∼45% on the word level, (ii) efficiency on both levels is strongly correlated with each other and (iii) efficiency tends to be higher for languages with more speakers.
Efficiency in discourse processing: Does morphosyntax adapt to accommodate new referents?
Authors: Schnell Stefan , Schiborr Nils Norman , Haig Geoffrey 
Published: April 2021

Abstract
The introduction of new referents into discourse has traditionally been regarded as a major challenge to language processing, for which speakers deploy specific syntactic configurations, guided by the speaker’s assessment of the recipient’s state of mind (‘recipient design’). In this paper we probe these assumptions against discourse data from nine languages. We find little evidence for specialized syntactic configurations accommodating new referents; the only notable exception is the association of new reference with direct objects, suggests that linking new referents to already established discourse frames through a transitive construction is preferable to isolating them in an intransitive one. Where specific intransitive predicates are indeed found to host new referents, we find this to be motivated primarily by semantic considerations. Contrary to long-held assumptions, we conclude that the cognitive challenge of referent introduction is only weakly reflected in morphosyntax; instead, discourse production is most efficient when new referents are integrated seamlessly with content-driven demands of the narration.
Efficiency in human languages: Corpus evidence for universal principles
Authors: Levshina Natalia , Moran Steven 
Published: April 2021

AbstractOver the last few years, there has been a growing interest in communicative efficiency. It has been argued that language users act efficiently, saving effort for processing and articulation, and that language structure and use reflect this tendency. The emergence of new corpus data has brought to life numerous studies on efficient language use in the lexicon, in morphosyntax, and in discourse and phonology in different languages. In this introductory paper, we discuss communicative efficiency in human languages, focusing on evidence of efficient language use found in multilingual corpora. The evidence suggests that efficiency is a universal feature of human language. We provide an overview of different manifestations of efficiency on different levels of language structure, and we discuss the major questions and findings so far, some of which are addressed for the first time in the contributions in this special collection.
New cyclic and spirocyclic aminosilanes
Authors: Herbig Marcus , Scholz Henrik , Böhme Uwe , Günther Betty , Gevorgyan Lia , Gerlach Daniela , Wagler Jörg , Schwarzer Sandra , Kroke Edwin 
Published: April 2021

AbstractNew cyclic and spirocyclic aminosilanes were synthesised using ethylenediamine, 2-aminobenzylamine, 1,8-diaminonaphthalene, o-phenylenediamine, andtrans-cyclohexane-1,2-diamine as starting material. These diamines were converted into aminosilanes using silicon tetrachloride and dimethyldichlorosilane directly and via theN,N’-bis(trimethylsilylated) amino derivatives. 15 new compounds of the type (diamino)(SiMe3)2, (diamino)2Si, (diamino)SiMe2, and (diamino)SiCl2have been prepared. The formation of two cyclotrisilazane derivatives was observed starting from (N,N’-2-aminobenzylamino)dichlorosilane by trimerisation. All synthesised compounds have been characterised with NMR-, Raman-, or IR-spectroscopy, mass-spectrometry, and boiling or melting point. Single-crystal X-ray structure analyses of several derivatives have been performed.The degree of substitution with trimethylsilyl groups in the final compounds depends on the ring size of the spirocycles. It was shown with quantum chemical calculations on the M062X/6-31G(d) level that trimethylsilyl groups have a stabilising effect on 5-membered ring systems and a destabilising effect on 6-membered rings in these compounds.
Two-dimensional perovskites with alternating cations in the interlayer space for stable light-emitting diodes
Authors: Zhang Yiyue , Keshavarz Masoumeh , Debroye Elke , Fron Eduard , Rodríguez González Miriam Candelaria , Naumenko Denys , Amenitsch Heinz , Van de Vondel Joris , De Feyter Steven , Heremans Paul , Roeffaers Maarten B. J. , Qiu Weiming , Pradhan Bapi , Hofkens Johan 
Published: April 2021

Abstract
Lead halide perovskites have attracted tremendous attention in photovoltaics due to their impressive optoelectronic properties. However, the poor stability of perovskite-based devices remains a bottleneck for further commercial development. Two-dimensional perovskites have great potential in optoelectronic devices, as they are much more stable than their three-dimensional counterparts and rapidly catching up in performance. Herein, we demonstrate high-quality two-dimensional novel perovskite thin films with alternating cations in the interlayer space. This innovative perovskite provides highly stable semiconductor thin films for efficient near-infrared light-emitting diodes (LEDs). Highly efficient LEDs with tunable emission wavelengths from 680 to 770 nm along with excellent operational stability are demonstrated by varying the thickness of the interlayer spacer cation. Furthermore, the best-performing device exhibits an external quantum efficiency of 3.4% at a high current density (J) of 249 mA/cm2 and remains above 2.5% for a J up to 720 mA cm−2, leading to a high radiance of 77.5 W/Sr m2 when driven at 6 V. The same device also shows impressive operational stability, retaining almost 80% of its initial performance after operating at 20 mA/cm2 for 350 min. This work provides fundamental evidence that this novel alternating interlayer cation 2D perovskite can be a promising and stable photonic emitter.
Flexural bearing capacity and failure mechanism of CFRP-aluminum laminate beam with double-channel cross-section
Authors: Huang Teng , Zhang Dongdong , Huang Yaxin , Fan Chengfei , Lin Yuan , Zhang Fukai 
Published: April 2021

Abstract
In this study, the flexural bearing capacity and failure mechanism of carbon fiber-reinforced aluminum laminate (CARALL) beams with a double-channel cross-section and a 3/2 laminated configuration were experimentally and numerically studied. Two types of specimens using different carbon fiber layup configurations ([0°/90°/0°]3 and [45°/0°/−45°]3) were fabricated using the pressure molding thermal curing forming process. The double-channel CARALL beams were subjected to static three-point bending tests to determine their failure behaviors in terms of ultimate bearing capacity and failure modes. Owing to the shortcomings of the two-dimensional Hashin failure criterion, the user-defined FORTRAN subroutine VUMAT suitable for the ABAQUS/Explicit solver and an analysis algorithm were established to obtain a progressive damage prediction of the CFRP layer using the three-dimensional Hashin failure criterion. Various failure behaviors and mechanisms of the CARALL beams were numerically analyzed. The results indicated that the numerical simulation was consistent with the experimental results for the ultimate bearing capacity and final failure modes, and the failure process of the double-channel CARALL beams could be revealed. The ultimate failure modes of both types of double-channel CARALL beams were local buckling deformation at the intersection of the upper flange and web near the concentrated loading position, which was mainly caused by the delamination failure among different unidirectional plates, tension and compression failure of the matrix, and shear failure of the fiber layers. The ability of each fiber layer to resist damage decreased in the order of 90° fiber layer > 0° fiber layer > 45° fiber layer. Thus, it is suggested that 90°, 0°, and 45° fiber layers should be stacked for double-channel CARALL beams.
Chronic restraint stress impairs cognition via modulating HDAC2 expression
Authors: Wu Jie , Liu Cui , Zhang Ling , He Bing , Shi Wei-Ping , Shi Hai-Lei , Qin Chuan 
Published: April 2021

Abstract

Background
To investigate the effects of chronic restraint stress on cognition and the probable molecular mechanism in mice.

Methods
In the current work, a restraining tube was used as a way to induce chronic stress in mice. The protein levels were determined with ELISA and western blot. A series of behavior tests, including the Morris water maze, elevated plus maze, open field test, and novel object recognition test, were also performed to examine the anxiety and the ability of learning and memory. Moreover, murine neuroblastoma N2a cells were used to confirm the findings from mice under chronic stress.

Results
Decreased synaptic functions were impaired in chronic stress with the downregulation of PSD95, GluR-1, the neurotrophic factor BDNF, and immediate-onset genes Arc and Egr. Chronic restraint decreased the histone acetylation level in hippocampal neurons while HDAC2 was increased and was co-localized with glucocorticoid receptors. Moreover, chronic stress inhibited the PI3K/AKT signaling pathway and induced energy metabolism dysfunctions.

Conclusion
This work examining the elevated levels of HDAC2 in the hippocampus may provide new insights and targets for drug development for treating many neurodegenerative diseases.
Circulating fatty acids and risk of gestational diabetes mellitus: prospective analyses in China
Authors: Pan Xiong-Fei , Huang Yichao , Li Xinping , Wang Yi , Ye Yi , Chen Huan , Marklund Matti , Wen Ying , Liu Yan , Zeng Huayan , Qi Xiaorong , Yang Xue , Yang Chun-Xia , Liu Ge , Gibson Robert A , Xu Shunqing , Yu Danxia , Chen Da , Li Yuanyuan , Mei Zhixiong , Pan An , Wu Jason H Y 
Published: April 2021

Objective
We aimed to examine prospective associations between circulating fatty acids in early pregnancy and incident gestational diabetes mellitus (GDM) among Chinese pregnant women.

Methods
Analyses were based on two prospective nested case-control studies conducted in western China (336 GDM cases and 672 matched controls) and central China (305 cases and 305 matched controls). Fasting plasma fatty acids in early pregnancy (gestational age at enrollment: 10.4 weeks(s.d., 2.0)) and 13.2 weeks (1.0), respectively) were determined by gas chromatography-mass spectrometry, and GDM was diagnosed based on the International Association of Diabetes in Pregnancy Study Groups criteria during 24–28 weeks of gestation. Multiple metabolic biomarkers (HOMA-IR (homeostatic model assessment for insulin resistance), HbA1c, c-peptide, high-sensitivity C-reactive protein, adiponectin, leptin, and blood lipids) were additionally measured among 672 non-GDM controls at enrollment.

Results
Higher levels of saturated fatty acids (SFAs) 14:0 (pooled odds ratio, 1.41 for each 1-s.d. increase; 95% CI: 1.25, 1.59) and 16:0 (1.19; 1.05, 1.35) were associated with higher odds of GDM. Higher levels of n-6 polyunsaturated fatty acid (PUFA) 18:2n-6 were strongly associated with lower odds of GDM (0.69; 0.60, 0.80). In non-GDM pregnant women, higher SFAs 14:0 and 16:0 but lower n-6 PUFA 18:2n-6 were generally correlated with unfavorable metabolic profiles.

Conclusions
We documented adverse associations of 14:0 and 16:0 but a protective association of 18:2n-6 with GDM among Chinese pregnant women. Our findings highlight the distinct roles of specific fatty acids in the onset of GDM.
Measurable Riesz spaces
Authors: Krasikova I. , Pliev M. , Popov M. 
Published: April 2021

We study measurable elements of a Riesz space $E$, i.e. elements $e \in E \setminus \{0\}$ for which the Boolean algebra $\mathfrak{F}_e$ of fragments of $e$ is measurable. In particular, we prove that the set $E_{\rm meas}$ of all measurable elements of a Riesz space $E$ with the principal projection property together with zero is a $\sigma$-ideal of $E$. Another result asserts that, for a Riesz space $E$ with the principal projection property the following assertions are equivalent.
(1) The Boolean algebra $\mathcal{U}$ of bands of $E$ is measurable.
(2) $E_{\rm meas} = E$ and $E$ satisfies the countable chain condition.
(3) $E$ can be embedded as an order dense subspace of $L_0(\mu)$ for some probability measure $\mu$.
Clinical and radiographic evaluation of demineralized freeze-dried bone allograft with concentrated growth factor versus concentrated growth factor alone in the treatment of intrabony defects
Authors: Vaid Tithi , Kumar Santosh , Mehta Rupal , Shah Sujay , Joshi Surabhi , Bhakkand Susmita , Hirani Tanvi 
Published: April 2021

Background. Periodontal disease is one of the major causes of alveolar bone loss. There are various ways of regenerating the lost bone, i.e. guided tissue regeneration, bone grafts, and growth factors. In this purview, it becomes immensely important for a clinician to decide the best modality of treatment. In this study, we compared the effect of demineralized freeze-dried bone allograft (DFDBA) in combination with concentrated growth factors (CGF) verses CGF alone.
Methods. This double-blind, split-mouth study was conducted on ten patients with two comparable bilateral intrabony defects. Each pair of defects was randomly treated by DFDBA + CGF or CGF alone. Clinical parameters such as plaque index (PI), modified gingival index (MGI), pocket probing depth (PPD), and relative attachment level (RAL) were recorded at baseline, three months, and six months. In addition, radiograph with grids was also taken at baseline and six months. The paired t-test was used to compare the pre- and post-treatment values and the unpaired t-test was used to compare the test and control group.
Results. The PI score decreased significantly from baseline to six months. Similarly, the mean MGI score decreased significantly from baseline to six months. The intragroup comparison showed that there was a significant reduction in PPD in both the test and control group. However, the intergroup comparison showed that the reduced pocket depth was not significant. The intragroup radiographic comparison showed that there was the significant formation of bone in both the test and control group but inter-group showed that the formation of bone among both the group were non-significant.
Conclusion. Radiographic and clinical outcomes of this study concluded that post six months, both groups demonstrated significant improvement in clinical and radiographic parameters. However, the addition of DFDBA to CGFs did not give any additional benefits.
Impact of self-esteem on the relationship between orthodontic treatment and the oral health-related quality of life in patients after orthodontic treatment – a systematic review
Authors: Mandava Prasad , Singaraju Gowri Sankar , Obili Sobitha , Nettam Venkatesh , Vatturu Sasipriya , Erugu Seshu 
Published: April 2021

Objective. The treatment protocol in the modern health care paradigm has shifted considerably towards enhancing the quality of life in the last decade. This is particularly important in cosmetic and elective treatments, and hence the interest in oral health-related quality of life (OHRQoL) also has increased. OHRQoL always been measured by endogenous, functional, social, or psychological determinants. Self-esteem (SE) is one of the internal factors that affect the perception of malocclusion and hence OHRQoL before and after treatment. The purpose of this review is to assess whether there exists any correlation between the Oral Health-Related Quality of Life, Self-esteem (SE) in patients following orthodontic treatment.
Methods. A literature search was confined to the English language using Medical Subject Heading terms (MeSH) in PubMed, Cochrane Library, and Ovid® covering the period from January 1, 1951 to May 15, 2020. Search in Google Scholar, grey literature, and hand search on cross-references was performed to find additional data. The studies found to be suitable were selected based on the predefined inclusion and exclusion criteria. The quality of assessment and risk of bias for the included studies were evaluated independently by two invigilators utilizing “The Cochrane Collaboration’s tool for assessing the risk of bias” and “Modified version of the Newcastle Ottawa scale” for Randomized Controlled Trials (RCTs) and non-randomized trials respectively.
Results. A total of 7688 studies were retrieved from all the sources. After screening all the titles and excluding the duplicates, 28 studies were finally included for text review, and all of them were fit for quality appraisal. The design of the final studies included comprised of 3 RCTs, 14 cohort studies, 9 cross-sectional studies, and 2 case-control studies.
Conclusion. There is moderate evidence to show that fixed orthodontic treatment improves OHRQoL and SE in children. OHRQoL also increased in adolescents and adults. However, there is a weak correlation between SE and OHRQoL. More evidence-based studies are needed to analyze the relationship.
VIRULENCE FACTORS, ANTIBIOTIC RESISTANCE, AND ANTIMICROBIAL ACTIVITY OF ENTEROCOCCUS SPP. ISOLATED FROM DIFFERENT SOURCES IN ALGERIA
Authors: Houicher Abderrahmane , Alkay Zuhal , Bourahla Mahdi , Dertli Enes 
Published: April 2021

This study aimed to isolate and identify different Enterococcus spp. from diverse sources including dromedary raw milk, rhizospheric soil and natural saline water samples and to determine their antimicrobial activities and safety aspects. From these sources, distinct strains of E. faecium, E. durans, E. hirae, and E. gallinarum species were detected. No virulence factors were observed for six Enterococcus strains while none of the tested Enterococci harboured the genes encoding cytolysin and aggregation substance. All tested strains showed a high sensitivity to many antibiotics, particularly vancomycin, and exhibited a remarkable antagonist activity toward Salmonella typhimurium, Fusarium graminearum and Penicillium expansum. PCR testing of enterocins revealed the co-presence of entA and entB among all tested Enterococci. No hemolytic reaction was also detected in Enterococci isolates, except for six strains. Based on these findings, potential candidates for use as biocontrol agents or probiotic starters were selected for further studies.