bluuebunny/crossref_metadata_2025_split huggingface dataset:
What is the impact of dexamethasone on postoperative pain in adults undergoing general anaesthesia for elective abdominal surgery: a systematic review and meta-analysis
Authors: Mitchell Ciara , Mitchell C. , Cheuk S. J. , O’Donnell C. M. , Bampoe S. , Walker D. 
Published: May 2021

Abstract
Background

Previous meta-analysis of heterogeneous surgical cohorts demonstrated reduction in postoperative pain with perioperative intravenous dexamethasone, but none have addressed adults undergoing elective abdominal surgery.
Objective

To determine the impact of intravenous perioperative dexamethasone on postoperative pain in adults undergoing elective abdominal surgery under general anaesthesia.
Methods

This review was prospectively registered on the international prospective register of systematic reviews (CRD42020176202). Electronic databases Medical Analysis and Retrieval System Online (MEDLINE), Exerpta Medica Database (EMBASE), (CINAHL) Cumulative Index to Nursing and Allied Health Literature (CINAHL), Cochrane Central Register of Controlled Trials (CENTRAL), Web of Science and trial registries were searched to January 28 2021 for randomised controlled trials, comparing dexamethasone to placebo or alternative antiemetic, that reported pain. The primary outcome was pain score, and secondary outcomes were time to first analgesia, opioid requirements and time to post-anaesthesia care unit (PACU) discharge.
Results

Fifty-two studies (5768 participants) were included in the meta-analysis. Pain scores ≤4 hours were reduced in patients who received dexamethasone at rest (mean difference (MD), -0.54, 95% confidence interval (CI) -0.72 to -0.35, I2 = 81%) and on movement (MD -0.42, 95% CI -0.62 to -0.22, I2 = 35 ). In the dexamethasone group 4–24 hour pain scores were less at rest (MD -0.31, 95% CI -0.47 to -0.14, I2 = 96) and on movement (MD -0.26, 95% CI -0.39 to -0.13, I2 = 29) and pain scores ≥24 hours were reduced at rest (MD -0.38, 95% CI -0.52 to -0.24, I2 = 88) and on movement (MD -0.38, 95% CI -0.65 to -0.11, I2 = 71). Time to first analgesia (minutes) was increased (MD 22.92, 95% CI 11.09 to 34.75, I2 = 98), opioid requirements (mg oral morphine) decreased (MD -6.66, 95% CI -9.38 to -3.93, I2 = 88) and no difference in time to PACU discharge (MD -3.82, 95% CI -10.87 to 3.23, I2 = 59%).
Conclusions

Patients receiving dexamethasone had reduced pain scores, postoperative opioid requirements and longer time to first analgesia. Dexamethasone is an effective analgesic adjunct for patients undergoing abdominal surgery.
Knowledge, Attitude, & Practice Regarding Environmental Hazards of Plastic Use
Authors: Gabuya Renno Jose 
Published: May 2021

This study looks into the knowledge, attitude, and practice of Barangay Bachao, Daram, Samar regarding environmental hazards of plastic use. Specifically it aims to: 1) identify the knowledge or information that residents possess regarding the danger of plastic use; 2) find out their attitude towards the use of plastic and the hazards it carries; and 3) identify their practices that might mitigate or perpetuate the hazards. Both quantitative and qualitative research designs were employed in the study. A survey was conducted among the 78 residents of the barangay and non-numerical data were also gathered from unstructured interviews.
Diallyl Disulfide Attenuates Methotrexate-Induced Hepatic Oxidative Injury,
Inflammation and Apoptosis and Enhances its Anti-Tumor Activity
Authors: Khalaf Marwa M. , Hassanein Emad H.M. , Shalkami Abdel-Gawad S. , Hemeida Ramadan A.M. , Mohamed Wafaa R. 
Published: May 2021

Background:
Methotrexate (MTX) is used potently for a wide range of diseases. However,
hepatic intoxication by MTX hinders its clinical use.

Objectives:
The present study was conducted to investigate the diallyl disulfide (DADS) ability to
ameliorate MTX-induced hepatotoxicity.

Methods:
Thirty-two rats were randomly divided into four groups: normal control, DADS (50
mg/kg/day, orally), MTX (single i.p. injection of 20 mg/kg) and DADS+MTX. Liver function biomarkers,
histopathological examinations, oxidative stress, inflammation, and apoptosis biomarkers
were investigated. Besides, an in vitro cytotoxic activity study was conducted to explore the modulatory
effects of DADS on MTX cytotoxic activity using Caco-2, MCF-7, and HepG2 cells.

Results:
DADS significantly reduced the increased serum activities of ALT, AST, ALP, and LDH.
These results were confirmed by the alleviation of liver histopathological changes. It restored the
decreased GSH content and SOD activity, while significantly decreased MTX-induced elevations
in both MDA and NO2
- contents. The hepatoprotective effects were mechanistically mediated
through the up-regulation of hepatic Nrf-2 and the down-regulation of Keap-1, P38MAPK, and NF-
κB expression levels. In addition, an increase in Bcl-2 level with a decrease in the expression of
both Bax and caspase-3 was observed. The in vitro study showed that DADS increased MTX antitumor
efficacy.

Conclusions:
DADS potently alleviated MTX-induced hepatotoxicity through the modulation of
Keap-1/Nrf-2, P38MAPK/NF-κB and apoptosis signaling pathways and effectively enhanced the
MTX cytotoxic effects, which could be promising for further clinical trials.
ANALISIS STRUKTUR IKLAN WARUNG BU KRIS
Authors: Yoga Pratama Agus Darma , Purwaningsih Ni Komang 
Published: May 2021

This research investigated advertising structure, strategy, and also the impact of advertising promotion on purchasing decisions of Warung Bu Kris’s food. The data in this study were collected through the observation method, namely by observing the use of words, phrases, sentences, icons, and images in food product advertisements and grouping them. The researcher used screenshots as a documentation technique in collecting the data and then categorizing them into groups. The data was analyzed based on the problems raised. The intralingual method used in this research. The finding showed that the structure in the food advertisement of Warung Bu Kris was headline-illustrations-body copy-signature line-standing details and headline-body copy-standing line. The advertising structure reflected the marketing strategy used by Warung Bu Kris’ owner, including establishing credentials, pressure tactics, and also offering incentives. The advertisements on Instagram influenced customer demand for food in terms of attitude towards the ad and click through rates.
Keywords: advertisement; food; promotion; structure
Four Bosons EM Conservation Laws
Authors: Doria R. M. , Soares I. 
Published: May 2021

Electromagnetism is expressed from two basic postulates. They are light invarianceand charge conservation. At this work one extends the Maxwell scenario from macroscopic to microscopic electromagnetism by following the elementary particles electric charge microscopic behavior. It yields a triune electric charge interrelationship. Three charges {+, 0, −} be exchanged through a vector bosons quadruplet. It is called Four Bosons Electromagnetism. A systemic EM physics appears to be understood. Maxwell photon is not enough for describing the microscopic electric charge physics. An extension for electromagnetic energy is obtained. The fields quadruplet {Aµ, Uµ, Vµ±} are the porters of electromagnetic energy. They are the usual photon Aµ, massive photon Uµ and two charged photons Vµ±, A new understanding on EM phenomena has to be considered. A set determinism based on granular and collective fields is developed. A space-time evolution associated to a whole.Conservation laws are studied. The EM phenomena is enlarged to three charges interchanges to {+, 0, −}. Two novelties appear. New features on nonlinear fields acting as own sources and on electric charge physics. Properties as conservation, conduction, transmission, interaction are extended to a systemic electromagnetism. A whole conservation law for electric charge emerges from three charges interwoven. Electric charge has a systemic behavior. Although there is no Coulomb law for zero electric charge, the Four Bosons Electromagnetism contains an EM energy which provides a neutral electromagnetism. Particles with zero charge {Aµ, Uµ} are carrying EM energy.
Another consideration is on EM energy being transported by four nonlinear fields. A new physicality appears. The abelian nonlinearity generates fields charges. Fields are working as own sources through mass terms, trilinear and quadrilinear interactions, spin couplings. Consequently the photon is more than being a consequence from electric charge oscillations. It is able to generate its own charge. Introduce the meaning of photonics.Thus, electric charge is no more the isolate electromagnetic source. There are another conservation laws. Fields sources appear through corresponding equations of motion, Bianchi identities, energy-momentum, Noether laws and angular momentum conservation laws. They move EM to a fields charges dependence. Together with electric charge they carrythe electromagnetic flux. Supporting the Ahranov-Bohm experiment of potential fields as primitive entities.
„Marzenia na emeryturze”? Aktywność marzenio-twórcza osób w drugiej połowie życia
Authors: Popielarz-Mróz Weronika 
Published: May 2021

Celem niniejszego artykułu jest prezentacja aktywności marzenio-twórczej podejmowanej przez osoby w okresie późnej dorosłości w oparciu o wyniki badań własnych, w którychuczestniczyło 10 osób (5 kobiet i 5 mężczyzn) w wieku powyżej 60 r.ż. Materiał badawczy pozyskany został przy pomocy pełnego narracyjnego wywiadu autobiograficznego, wybranychkart wchodzących w skład narracyjnej gry (auto)biograficznej W osiemdziesiąt historii dookoła życia Urszuli Tokarskiej oraz autorskiego Testu Zdań Niedokończonych.
Analiza materiału pozwoliła na dokonanie charakterystyki aktualnych marzeń seniorów oraz opisanie relacji, w jakiej pozostają do własnych marzeń. Uzyskane wyniki umożliwiły sformułowanie stadialnego modelu rozwoju marzenia oraz wyróżnienie nowej kategorii marzenia nazwanego marzeniem generacyjnym. Wnioski płynące ze zrealizowanego projektu badawczego odsłaniają potencjalne możliwości aplikacyjne zarówno w obszarze psychologii wspomagania rozwoju człowieka dorosłego, jak i optymalizacji komunikacji międzypokoleniowej oraz doskonalenia narzędzi umożliwiających poznanie człowieka oraz podejmowanie oddziaływań psychologicznych w obszarze gerontologii narracyjnej.
Satysfakcja z życia u osób trenujących i nietrenujących karate
Authors: Potoczny Wiktor 
Published: May 2021

Badania nad zadowoleniem z życia oraz dobrostanem psychicznym to szeroki i wciąż rozwijający się obszar psychologii. Karate jako specyficzna aktywność fizyczna może wiązać sięz satysfakcją z życia. Celem badania był pomiar poziomu zadowolenia z życia u osób regularnie trenujących karate, w porównaniu z osobami niepodejmującymi regularnych aktywnościfizycznych oraz zbadanie relacji pomiędzy czasem trwania i częstotliwością treningu a poziomem satysfakcji z życia.
Po przebadaniu 112 osób, dobranych celowo do dwóch równolicznych grup (osoby regularnie trenujące karate vs. nietrenujące) analiza przy użyciu Skali Satysfakcji z Życia (SWLS) wykazała, że poziom satysfakcji z życia u osób regularnie trenujących karate jest istotnie wyższy. W badaniu wykazano także dodatnią korelację pomiędzy stażem treningowym a satysfakcją z życia. Związek pomiędzy częstotliwością treningu a satysfakcją z życia okazał się nieistotny. Otrzymane rezultaty poszerzają wiedzę na temat zadowolenia z życia w odniesieniu do aktywności fizycznych oraz mogą stanowić podstawę do prowadzenia dalszych analiz.
The Correlation Analysis Between Critical Thinking Skills And Learning Outcomes Through Implementation Of Guided Inquiry Learning Models
Authors: Muhan Laiaza Aghenia , Nasrudin Harun 
Published: May 2021

The 21st-century learning process highlights the critical thinking skills concept. Critical thinking has the highest chance of impacting students' learning outcomes. One of the learning models to increase critical thinking skills was guided inquiry. This research aimed to analyze the correlation between critical thinking skills and learning outcomes on reaction rates topic using the Guided Inquiry learning model. This research used a correlational design. Subjects were students of SMA Negeri 1 Krian class XI MIPA 6 odd semester in the academic year 2020/2021 as many as 34 people. The data were obtained using the observation sheets instrument for the implementation of the guided inquiry learning model, the critical thinking skills test sheets, and the learning outcomes test sheets. Data were analyzed using Pearson correlation and linear regression analysis used (α) 0.05. The results indicated that there was a significant positive correlation between critical thinking and learning outcomes on reaction rates topic using the Guided Inquiry learning model. The correlation regression equation obtained between the two variables is Y = -16.575 + 1.170X with reliability value 76,3%. The N-gain score obtained for each indicator of critical thinking skills and learning outcomes ≥ 0.7 at high criteria.
Potensi Pengadaan Tanah Berbasis Kebencanaan di Kota Palu
Authors: Rakhmawan Mokhamad Usman , Sutaryono Sutaryono , Setiowati Setiowati 
Published: May 2021

Berdasarkan hasil studi dari tim revisi peta gempa Indonesia (dalam Irsyam, M, dkk, 2010) struktur geologi aktif yang melewati Kota Palu adalah berupa PKF (Palu Koro Fault) dan MF (Matano Fault) keduanya merupakan sesar aktif yang banyak dijumpai disekitar lembah Palu. Rentetan bencana yang terjadi pada tanggal 28 September 2018 disebabkan adanya pergerakan tektonik pada Patahan Palu Korro. Oleh sebab itu Kota Palu diharuskan memiliki tindakan mitigasi bencana. Setelah adanya zonasi ruang rawan bencana di Kota Palu dan sekitarnya yang membagi Kota Palu menjadi 4 Zonasi yaitu ZRB 4, ZRB 3, ZRB 2 dan ZRB 1. Kemudian adanya Penetapan Lokasi Pengadaan Tanah yang direncanakan untuk dibangun hunian tetap untuk korban bencana yang bertampalan dengan ZRB 3, dimana dalam zonasi ini ada larangan untuk membangun hunian baru diatasnya serta ada yang bertampalan dengan hak kepemilikan masyarakat. Sehingga perlu adanya tindakan mitigasi bencana berupa Peta Potensi Pengadaan Tanah Berbasis Kebencanaan. Dalam peta ini memberikan informasi lokasi-lokasi yang berada diluar ZRB 4 dan ZRB 3 serta tidak bertampalan dengan Hak Kepemilikan Masyarakat.
Évaluation des pratiques d’un dispositif de prévention des vulnérabilités périnatales : les staffs médico-psychosociaux
Authors: Roth B. , Einaudi M.-A. , Tardieu S. , Bernard O. 
Published: May 2021

Objectif : La prévention périnatale des vulnérabilités médico-psychosociales se traduit par la mise en œuvre de staffs médico-psychosociaux (MPS) dans les maternités. Les objectifs de cette étude étaient de réaliser un état des lieux des staffs MPS de la région Provence-Alpes-Côte d’Azur (PACA) et d’explorer les enjeux éthiques liés aux pratiques des professionnels impliqués dans ce dispositif.
Méthodes : Cette étude descriptive mixte a été réalisée en deux phases : une première phase interrogeant les coordonnateurs des staffs MPS de la région via un autoquestionnaire ; une seconde phase consistant en des entretiens semi-directifs auprès des coordonnateurs des staffs MPS du département des Bouches-du-Rhône.
Résultats : Pour la première phase de l’étude, le taux de participation était de 83 %. Pour la seconde phase, dix entretiens semi-dirigés ont été menés auprès des coordonnateurs des staffs du département. L’enquête a permis de révéler un « noyau dur » de professionnels participant régulièrement aux réflexions du staff (équipe PMI, psychologue, sagefemme et assistante sociale hospitaliers), ainsi que le respect du cadre réglementaire concernant le partage d’informations, restant malgré tout confus pour les coordonnateurs. Enfin, les enjeux éthiques soulevés par ces situations de vulnérabilité ont été explorés (partage d’information, modalités décisionnelles, représentations).
Conclusion : Cet état des lieux a permis de révéler les points forts (dispositif bien implanté sur le territoire, respect du cadre réglementaire, professionnels impliqués…) et éléments à améliorer (repérage anténatal, lien avec la psychiatrie adulte…) concernant ces staffs, et permettra de guider les politiques de santé régionales en faveur de la périnatalité.
First-year mortality in living donor kidney transplantation: twelve-year experience from a single center
Authors: MERHAMETSİZ Özgür , DEMİR Mehmet Emin , SEVMİS Murat , UYAR Murathan , AKTAS Sema , SEVMİŞ Şinasi 
Published: May 2021

Objective: The mortality was seen in the early period after kidney transplantation is one of the most undesirable consequences of kidney transplant treatment. This study was aimed to evaluate the factors affecting the 1st-year mortality in patients who underwent living donor kidney transplantation (LDKT) in our center.
Material and Methods: Adult patients who underwent LDKT developed mortality within the 1st-year in our center between 2008 and 2020. Mortality group and the control group are compared according to donor and recipient characteristics. The risk factors that have an adjusted effect on 1st-year mortality after kidney transplantation were evaluated by cox regression survival analysis.
Results: Total mortality incidence was 8.35% and the 1st-year mortality incidence was 1.67%. Median dialysis duration (13 months vs. 3 months) was longer in the mortality-group, p=0.022. Cardiovascular disease (CVD) was more common in the mortality-group (50% vs. 31.1%), p=0.037. Median HLA mismatch numbers was higher in the mortality-group (4 vs. 3), p=0.027. According to Model 1, in terms of 1st- year mortality, each 1 year increment in recipient's age increases the mortality by 1,034 times, and dialysis treatment increases the mortality 2.5 times. According to Model 2, in terms of 1st-year mortality, each 1 year increment in recipient's age increase the mortality by 1,039 times, dialysis treatment increases the mortality 2.8 times and each 1 mismatch increase in HLA mismatch numbers increases the mortality by 1.3 times. Receiver operating characteristic analysis showed that the moderate predictive power for recipient age was AUC 0.734 (95% CI 0.623-0.844, p
A key challenge in gestational diabetes screening: resistance to oral glucose tolerance test screening and implications for neonatal health
Authors: TURSUN Serkan , YERAL İlkin , YILDIZ Volkan , ÜNAL Elif , GUZOGLU Nilufer , ALİEFENDİOĞLU Didem 
Published: May 2021

Objective: Gestational diabetes mellitus (GDM) is the most common endocrine disorder in pregnancy and the number of pregnant women resistant to oral glucose tolerance test (OGTT) has increased significantly in recent years. In this study, we investigated the extent of resistance to OGTT screening in pregnant women followed-up in our hospital and the effect of this situation on the newborn.
Material and Method: Pregnant women and their babies who were followed up regularly for 25 months (December 1, 2015- December 31, 2017) in the obstetrics and gynecology clinic of our hospital were included in our study. The relationship between OGTT and clinicopathological findings was analyzed.
Results: The cesarean (C/S) delivery rate was significantly lower in the babies of mothers who did not have the OGTT test (p
Our experience of laser lithotripsy under local anesthesia in the treatment of bladder stones in obese male patients
Authors: KÖLÜKÇÜ Engin , PARLAKTAŞ Bekir Süha , KÖLÜKÇÜ Vildan , SARIKAYA Kubilay , ŞENOCAK Çağri , BOZKURT Ömer Faruk 
Published: May 2021

Introduction: Our century has witnessed a significant increase in obesity, which in its turn, bears several major risks in management of systemic anesthesia. In this context, use of this treatment without general or regional anesthesia is of critical importance for patients under this group.
Aim: In present study, it was aimed to analyze the efficacy and safety of holmium laser lithotripsy (HLL) under local anesthesia in obese male patients with bladder stones.
Material and Method: In our study, we evaluated a total of 64 obese male patients with body mass index (BMI) ≥ 30 kg/m2, diagnosed with bladder stones and treated HLL under local anesthesia. Demographic data, stone size, operative time, urethral catheterization time and length of hospital stay of the patients were analyzed. Visual Analogue Scale (VAS) scores was calculated for each patient during the procedure. Complications were graded according to modified Clavien classification system.
Results: The mean age of patients was 50.58 ± 13.04 years and BMI was 33.46 ± 2.59 kg/m2. Mean stone size was 2.51 ± 1.04 cm and operative time was 43.91 ± 15.92 minutes. None of the patients had severe pain and the mean VAS score was calculated as 2.31 ± 1.02. Mean length of hospital stay was 1.25 ± 1.04 days. Grade 3 or higher complications were not observed according to modified Clavien classification system. Mean urethral catheterization time was 1.56 ± 1.45 days, although varying due to underlying etiological factor. All patients were stone-free and there was a marked improvement in clinical findings.
Conclusion: Use of HLL under local anesthesia is a safe and efficacious approach in obese male patients with bladder stone.
Az anyagcentrikus hadikultúra megjelenése a tengeri hadviselésben
Authors: Leib Péter 
Published: May 2021

Tanulmányomban az anyagcentrikus hadikultúra tengeri hadviselésben történő megjelenésével kívánok foglalkozni. Az első részben definiálom a hadikultúra fogalmát, illetve bemutatom a mozgás-, az anyagcentrikus, illetve a gerilla- hadikultúrák általános jellemzőit. Az írás második részében azt vizsgálom, hogy a tengeri hadviselésben hogyan jelennek meg az anyagcentrikus hadikultúra jellemzői. Ennek bemutatására a tengeri hadelmélet két stratégájának, Alfred Thayer Mahan és Sir Julian Stafford Corbett munkásságára támaszkodom.
OPTIMALISASI PRODUKSI SAWI (Brassica juncea, L.) PADA JENIS PUPUK KANDANG DAN KONSENTRASI PUPUK HAYATI
Authors: Subali Joko 
Published: May 2021

Tanaman sayuran sawi berperan penting dalam kehidupan sehari-hari karena memiliki kadar air yang tinggi, nutrisi, pembentuk sifat basa, kaya akan vitamin dan mineral, rendah kalori, serta kaya akan serat. Salah satu kendala yang dihadapi pada budidaya tanaman sawi adalah kandungan bahan organik tanahnya yang rendah sehingga kurang mendukung pertumbuhan tanaman. Upaya untuk mengatasi masalah tersebut dilakukan melalui pemupukan menggunakan pupuk organik seperti pupuk kandang. Selain pemberian pupuk kandang, pemberian pupuk hayati juga merupakan salah satu upaya dalam mengoptimalisasi produksi sawi.Tujuan penelitian ini untuk mengetahui optimalisasi produksi sawi (Brassica juncea L.) pada jenis pupuk kandang dan konsentrasi pupuk hayati, serta interaksi kedua perlakuan tersebut. Penelitian ini dilaksanakan di Desa Sidodadi Kecamatan Langsa Kota, Kota Langsa dengan pH tanah 6,5 dan ketinggian tempat 8-10 meter di atas permukaan laut (m dpl). Rancangan yang digunakan di dalam penelitian ini adalah menggunakan Rancangan Acak Kelompok (RAK) pola faktorial yang terdiri dari 2 faktor. Faktor pertama jenis pupuk kandang (J), dan faktor kedua konsentrasi pupuk hayati Bioboost (K). Interaksi perlakuan jenis pupuk kandang dan konsentrasi pupuk hayati Bioboost berpengaruh nyata terhadap parameter jumlah daun umur 14 HST, sedangkan parameter lain berpengaruh tidak nyata. Interaksi terbaik terdapat pada kombinasi pupuk kandang ayam dengan konsentrasi pupuk hayati Bioboost 120 cc/liter air.