bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical Efficacy and Safety Comparison of Rivaroxaban and Dabigatran for Nonvalvular Atrial Fibrillation Patients Undergoing Percutaneous Left Atrial Appendage Closure Operation
Authors: Li Xiaoye , Zhang Xiaochun , Jin Qinchun , Xue Ying , Lu Wenjing , Ge Junbo , Zhou Daxin , Lv Qianzhou 
Published: June 2021

Objective: Due to the clinical complexity of warfarin, novel oral anticoagulation (NOAC) has been a feasible and safe alternative anticoagulant approach during left atrial appendage closure (LAAC). This study was designed to compare the efficacy and safety of rivaroxaban and dabigatran for nonvalvular atrial fibrillation patients undergoing percutaneous LAAC.Methods: One single and prospective cohort study was performed among patients who received anticoagulation with dabigatran or rivaroxaban. All patients were medicated with a 3-month course of NOAC to facilitate device endothelialization, followed by dual antiplatelet therapy until 6 months, then lifelong aspirin after discharge. Repeated transesophageal echocardiography was scheduled to evaluate thrombosis formation on occluders and thrombus dissolution ability.Results: A total of 262 consecutive patients were initially enrolled. A final number of 250 patients were analyzed; two patients were excluded due to procedure failure and 10 patients had a loss of follow-up; 97 were from the dabigatran group and 153 from the rivaroxaban group. Three patients (1.9%) in the rivaroxaban group and eight (8.2%) in the dabigatran group were experiencing device-related thrombosis (DRT) events during follow-ups. Cumulative Kaplan–Meier estimates showed that the incidence of DRT was lower under rivaroxaban medication during the 6-month follow-ups (p = 0.038*, OR = 3.843, 95%CI: 0.991–14.836). The transesophageal echocardiography (TEE) results showed that the average length and width of DRT in the rivaroxaban group was significantly lower compared with that in the dabigatran group (2.16 vs. 1.60 mm, p = 0.017*, and 1.71 vs. 1.30 mm, p = 0.003*, respectively). The thrombosis dissolved after the switch from dabigatran or rivaroxaban to warfarin within the target range, represented by the average length and width of thrombus with the cooperation of secondary TEE for the dabigatran and rivaroxaban groups (0.64 vs. 0.40 mm, p = 0.206, and 0.43 vs. 0.27 mm, p = 0.082, respectively). No significant difference was found between the two groups with respect to the levels of coagulation parameters, cardiac function, and bleeding events.Conclusion: Compared to dabigatran, post-procedural rivaroxaban anticoagulation might be advantageous in preventing DRT complications expected after LAAC, without increasing the risk of hemorrhage.
Exercise Addiction and Muscle Dysmorphia: The Role of Emotional Dependence and Attachment
Authors: Olave Leticia , Estévez Ana , Momeñe Janire , Muñoz-Navarro Roger , Gómez-Romero María José , Boticario María Jesús , Iruarrizaga Itziar 
Published: June 2021

Background: Both exercise addiction (EA) and muscle dysmorphia (MD) primarily involve the compulsive practice of physical exercise and are classified as behavioral addictions in different lines of research. These types of addictions are frequently comorbid with other addictive pathologies, such as emotional dependence (ED), which is closely related to childhood attachment. This study is presented to address the scarcity of research relating EA and MD with other behavioral addictions. The aims are to analyze the sex differences found in emotional dependence, attachment dimensions, EA and MD; to analyze the association between EA and MD and other behavioral addictions, such as emotional dependence and attachment dimensions; and to analyze the possible role that childhood attachment plays in mediating the interaction between emotional dependence and EA and MD.Method: The sample comprised 366 participants (54.6% women) aged 17–31 (M = 23.53; SD = 6.48).Results: There are sex differences, with men scoring higher in EA, MD, and ED. The positive relationship between EA and ED (values between 0.16 and 0.28), MD (presenting values between 0.42 and 0.70), and attachment styles based on preoccupation, interference, permissiveness, and value of parental authority (values between 0.11 and 0.14) is highlighted. On the other hand, MD was positively related to ED (values ranging from 0.24 to 0.36) and attachment styles based on the value of parental authority, self-sufficiency, and resentment toward parents (between 0.17 and 0.18), and negatively related to secure attachment (values between −0.13 and −0.18). Likewise, the predictive role of ED and attachment styles in EA and MD was tested. And it was observed how attachment styles mediated the relationship between EA and ED, as well as the relationship between MD and ED. Thus, it has been shown that people with EA and MD present attachment styles that may influence negatively the decision-making process when choosing inappropriate strategies to achieve adequate emotional regulation, even selecting inappropriate goals for physical exercise with negative consequences.Conclusions: The dissemination of the findings among mental health and sports science professionals is necessary to develop prevention and intervention strategies for people affected by EA and MD.
Risk Factors for Anxiety and Depressive Symptoms in Doctors During the Coronavirus Disease 2019 Pandemic
Authors: He Lanying , Wang Jian , Zhang Lijuan , Wang Feng , Dong Weiwei , Zhao Wang 
Published: June 2021

Background: The purpose of our study was to investigate the prevalence of anxiety and depressive symptoms and their risk factors among doctors during the coronavirus disease 2019 (COVID-19) pandemic.Methods: A hospital-based survey study was conducted. Anxiety symptoms were assessed using the Self-Rating Anxiety Scale (SAS), and depressive symptoms were assessed using the Self-Rating Depression Scale (SDS). Multivariable logistic regression was used to analyze anxiety and depressive symptoms across independent variables.Results: A total of 1,521 doctors were included; 11.11% (169/1,521) of the doctors had anxiety symptoms, and 16.90% (257/1,521) had depressive symptoms. Female sex [adjusted odds ratio (aOR), 1.69; 95% confidence interval (CI), 1.21–2.34; P = 0.002] and having a minor child (aOR, 2.31; 95% CI, 1.50–3.56; P &lt; 0.001) were associated with an increased risk of anxiety symptoms. Female sex (aOR, 1.56; 95% CI, 1.18–2.06; P = 0.002) and having a minor child (aOR, 1.48; 95% CI, 1.06–2.01; P = 0.022) were associated with an increased risk of depressive symptoms. Older age (aOR, 0.97; 95% CI, 0.98–0.99; P = 0.008) was associated with a decreased risk of depressive symptoms.Conclusions: Anxiety and depressive symptoms have been common mental health problems in doctors during the COVID-19 pandemic. We found that female sex, having a minor child, and younger age were major risk factors for the development of anxiety and depressive symptoms among doctors during the COVID-19 pandemic.
Perceived Stress During the First Wave of COVID-19 Outbreak: Results From Nationwide Cross-Sectional Study in Estonia
Authors: Reile Rainer , Kullamaa Lembe , Hallik Reeli , Innos Kaire , Kukk Maarja , Laidra Kaia , Nurk Eha , Tamson Merili , Vorobjov Sigrid 
Published: June 2021

Objective: To study the population-level mental health responses during the first wave of coronavirus disease 2019 (COVID-19) outbreak in Estonia and analyze its socio-demographic, behavioral, and health-related variations among general population.Methods: This study used nationally representative data on 4,606 individuals, aged 18–79 years from a rapid-response cross-sectional survey conducted in April 2020. Point prevalence and mutually adjusted prevalence rate ratios for perceived stress from log-binomial regression analysis were presented for socio-demographic, behavioral, and health-related variables.Results: This study found that 52.2% of population aged 18–79 reported elevated stress levels in relation to COVID-19 outbreak. Higher levels of perceived stress were found in women, in younger age groups, in Estonians, and in those with higher self-perceived infection risk, presence of respiratory symptoms, and less than optimal health, according to self-reports.Conclusion: Although, the potential long-term health effects of the current crisis are yet unknown, the alarmingly high stress levels among people indicate that the COVID-19 pandemic might have had a widespread effect on people's mental health.
Therapeutic Effect of Large Channel Endoscopic Decompression in Lumbar Spinal Stenosis
Authors: Wei Fei-Long , Du Ming-Rui , Li Tian , Zhu Kai-Long , Zhu Yi-Li , Yan Xiao-Dong , Yuan Yi-Fang , Wu Sheng-Da , An Bo , Gao Hao-Ran , Qian Ji-Xian , Zhou Cheng-Pei 
Published: June 2021

Background: Percutaneous endoscopic decompression (PED) is a minimally invasive surgical technique that is now used for not only disc herniation but also lumbar spinal stenosis (LSS). However, few studies have reported endoscopic surgery for LSS. Therefore, we conducted this study to evaluate the outcomes and safety of large channel endoscopic decompression.Methods: Forty-one patients diagnosed with LSS who underwent PED surgery were included in the study. The estimated blood loss, operative time, length of hospital stay, hospital costs, reoperations, complications, visual analogue scale (VAS) score, Oswestry Disability Index (ODI) score, Japanese Orthopaedic Association (JOA) score and SF-36 physical-component summary scores were assessed. Preoperative and postoperative continuous data were compared through paired-samples t-tests. The significance level for all analyses was defined as p &lt; 0.05.Results: A total of 41 consecutive patients underwent PED, including 21 (51.2%) males and 20 (48.8%) females. The VAS and ODI scores decreased from preoperatively to postoperatively, but the JOA and SF-36 physical component summary scores significantly increased. The VAS (lumbar) score decreased from 5.05 ± 2.33 to 0.45 ± 0.71 (P = 0.000); the VAS (leg) score decreased from 5.51 ± 2.82 to 0.53 ± 0.72 (P = 0.000); the ODI score decreased from 52.80 ± 20.41 to 4.84 ± 3.98 (P = 0.000), and the JOA score increased from 11.73 ± 4.99 to 25.32 ± 2.12 (P = 0.000). Only 1 patient experienced an intraoperative complication (2.4%; dural tear), and 1 patient required reoperation (2.4%).Conclusions: Surgical treatment for LSS is to sufficiently decompress and minimize the trauma and complications caused by surgery. This study did not reveal any obvious shortcomings of PED and suggested PED is a safe and effective treatment for LSS.
Case Report: Liver Cysts and SARS-CoV-2: No Evidence of Virus in Cystic Fluid
Authors: D'Amico Francesco Enrico , Glavas Dajana , Noaro Giulia , Bassi Domenico , Boetto Riccardo , Gringeri Enrico , De Luca Maurizio , Cillo Umberto 
Published: June 2021

Background: In December 2019, an outbreak of pneumonia, caused by a new type of coronavirus, named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). It quickly spread worldwide, resulting in a pandemic. The clinical manifestations of SARS-CoV-2 range from mild non-specific symptoms to severe pneumonia with organ function damage. In addition, up to 60% of patients have liver impairment or dysfunction, confirmed by several studies by the presence of SARS-CoV-2 in the liver tissue.Methods: We report two cases of symptomatic liver cyst requiring fenestration after recent SARS-CoV-2 infection. Both patients had hospital admission due to documented SARS-CoV-2 infection. Recently, after the infection, they developed symptoms caused by an enlarged hepatic cyst: one had abdominal pain, and the other had jaundice. They underwent surgery after two negative swab tests for SARS-CoV-2.Results: Cystic fluid was sent for microbiological test, and real-time fluorescence polymerase chain reaction COVID-19 nucleic-acid assay of the cyst fluid was found to be negative in both cases.Discussion: Although there are no current data that can document a viral contamination of cystic fluid, there are data that document a hepatotropism of COVID-19 virus. Herein we report that after viral clearance at pharyngeal and nasal swab, there is no evidence of viral load in such potential viral reservoir.
ЗВІТ НАЦІОНАЛЬНОЇ АКАДЕМІЇ ПЕДАГОГІЧНИХ НАУК УКРАЇНИ ПРО СТАН ВИКОРИСТАННЯ КОШТІВ НА НАУКОВУ І НАУКОВО-ТЕХНІЧНУ ДІЯЛЬНІСТЬ ТА ОТРИМАНІ РЕЗУЛЬТАТИ ЗА 2020 р.
Authors: Кремень Василь Григорович 
Published: June 2021

У доповіді висвітлено результати наукової діяльності Національної академії педагогічних наук України у 2020 р., її підвідомчих установ, розвитку кадрового потенціалу. Представлено найважливіші досягнення вчених НАПН України у науковому і методичному забезпеченні дошкільної, повної загальної середньої, професійної (професійно-технічної), фахової передвищої, вищої освіти і освіти дорослих, освіти дітей з різними порушеннями розвитку та переходу до інклюзивного навчання, цифровізації освіти та дистанційного навчання, психологічної підтримки розвитку особистості, зокрема в умовах складних соціальних обставин, розвитку психологічної служби системи освіти в процесі децентралізації. Наведено вагомі здобутки дослідників НАПН України за результатами ґрантових проєктів Національного фонду досліджень України та у межах виконання міжнародних проєктів. Зазначено основні показники діяльності у 2020 р. щодо наукових публікацій вчених, зокрема істотного зростання кількості праць у наукометричних базах даних Web of Science і Scopus, формування і використання ресурсу Електронної бібліотеки НАПН України, підвищення якості наукових періодичних видань, співпраці з органами державної влади, організаціями, установами, закладами, розширення експертної та експериментальної діяльності, підготовки здобувачів наукових ступенів доктора філософії і доктора наук, діяльності спеціалізованих вчених рад, роботи з молодими вченими, міжнародної співпраці, науково-практичних масових заходів тощо. Привернуто увагу до нерозв’язаних проблем та окреслено перспективи розвитку академії. Наголошено на спроможності вчених НАПН України комплексно вирішувати актуальні проблеми розвитку освіти та людини в ній, забезпечувати системне і планове проведення наукових досліджень у галузі освіти, педагогіки і психології.
La educación en el mundo global
Authors: González Castañeda Martha Alexandra 
Published: June 2021

Esta reflexión realizada a partir de la lectura y el análisis de algunos documentos que abordan el tema de la globalización y la educación, permiten hacer el recorrido por pensamientos, realidades y en general por diversos puntos de vista que convergen en el reconocimiento de la educación como la mejor y máxima posibilidad de formar al ser humano. El objetivo general de esta reflexión es considerar la perspectiva global como una extensión lógica de la sociología de la educación, a fin de encontrar elementos pedagógicos comunes de las distintas sociedades interconectadas en la dinámica educativa mundial. Se abordan los temas de la globalización, su relación con la educación, la política pública, el valor social de la educación en el mundo globalizado y la crisis actual de los sistemas de valor en la escuela. Finaliza brindando conclusiones que invitan a continuar este ejercicio de praxis para continuar repensando y planteando propuestas transformadoras de la realidad que le sigan apostando al mejoramiento de la calidad educativa de nuestro país.
Alfabetizar, una experiencia pedagógica llena de sentidos
Authors: Riaño Sastoque Mary Luz , Triviño Páez Nelly Yohana 
Published: June 2021

Este artículo relata las experiencias de dos estudiantes de Licenciatura en Pedagogía Infantil (LPID) de IX semestre en la Corporación Universitaria Minuto de Dios (UNIMINUTO) desde el modelo praxeológico, interesadas en divulgar el trabajo realizado en el marco del convenio con la Asociación Colombiana de Universidades (ASCUN), en la implementación del Modelo Educativo Flexible (MEF) Propuesta para Cambiar Entornos Sociales (PACES) con adultos de los municipios Ubaté y Lenguazaque (Cundinamarca). En este documento se aprecia una perspectiva diferente del rol que desempeña una pedagoga infantil en procesos de lectoescritura con adultos, donde las experiencias van más allá de las letras, generando cambios significativos a los estudiantes independientemente de su edad, así como el elevado interés por la elaboración de sus trabajos, capacidad de liderazgo, autonomía e independencia que permiten transformar contextos y generar ambientes pedagógicos significativos en estas poblaciones desde la formación como pedagogas infantiles.
Kinematics of the Circumgalactic Medium of a z = 0.77 Galaxy from Mg ii Tomography
Authors: Mortensen Kris , Vasan G. C. Keerthi , Jones Tucker , Faucher-Giguère Claude-André , Sanders Ryan L. , Ellis Richard S. , Leethochawalit Nicha , Stark Daniel P. 
Published: June 2021

Abstract
Galaxy evolution is thought to be driven in large part by the flow of gas between galaxies and the circumgalactic medium (CGM), a halo of metal-enriched gas extending out to ≳100 kpc from each galaxy. Studying the spatial structure of the CGM holds promise for understanding these gas flow mechanisms; however, the common method of using background quasar sight lines provides minimal spatial information. Recent works have shown the utility of extended background sources such as giant gravitationally lensed arcs. Using background lensed arcs from the CSWA 38 lens system, we continuously probed, at a resolution element of about 15 kpc2, the spatial and kinematic distribution of Mg ii absorption in a star-forming galaxy at z = 0.77 (stellar mass ≈109.7
M
⊙, star formation rate ≈10 M
⊙ yr−1) at impact parameters D ≃ 5–30 kpc. Our results present an anisotropic, optically thick medium whose absorption strength decreases with increasing impact parameter, in agreement with the statistics toward quasars and other gravitational arcs. Furthermore, we find generally low line-of-sight velocities in comparison to the relatively high velocity dispersion in the Mg ii gas (with typical σ ≈ 50 km s−1). While the galaxy itself exhibits a clear outflow (with Mg ii velocities up to ∼500 km s−1) in the down-the-barrel spectrum, the outflow component is subdominant and only weakly detected at larger impact parameters probed by the background arcs. Our results provide evidence of mainly dispersion-supported, metal-enriched gas recycling through the CGM.
Modified Gravity and the Flux-weighted Gravity–Luminosity Relationship of Blue Supergiant Stars
Authors: Sextl Eva , Kudritzki Rolf-Peter , Weller Jochen , Urbaneja Miguel A. , Weiss Achim 
Published: June 2021

Abstract
We calculate models of stellar evolution for very massive stars and include the effects of modified gravity to investigate the influence on the physical properties of blue supergiant stars and their use as extragalactic distance indicators. With shielding and fifth force parameters in a similar range as those in previous studies of Cepheid and tip of the red giant branch (TRGB) stars, we find clear effects on stellar luminosity and flux-weighted gravity. The relationship between flux-weighted gravity, g

F
≡ g/

, and bolometric magnitude M
bol, which has been used successfully for accurate distance determinations, is systematically affected. While the stellar evolution of flux-weighted gravity–luminosity relationships (FGLRs) show a systematic offset from the observed relation, we can use the differential shifts between models with Newtonian and modified gravity to estimate the influence on FGLR distance determinations. Modified gravity leads to an increase in distance of 0.05–0.15 magnitudes in distance modulus. These changes are comparable to the ones found for Cepheid stars. We compare observed FGLR and TRGB distances of nine galaxies to constrain the free parameters of modified gravity. Not accounting for systematic differences between TRGB and FGLR distances shielding parameters of 5 × 10−7 and 10−6 and fifth force parameters of 1/3 and 1 can be ruled out with about 90% confidence. Allowing for potential systematic offsets between TRGB and FGLR distances no determination is possible for a shielding parameter of 10−6. For 5 × 10−7 a fifth force parameter of 1 can be ruled out to 92% but 1/3 is unlikely only to 60%.
Improving NASA/IPAC Extragalactic Database Redshift Calculations
Authors: Carr Anthony , Davis Tamara 
Published: June 2021

Abstract
The NASA/IPAC Extragalactic Database (NED) is an impressive tool for finding near-exhaustive information on millions of astrophysical objects. Here, we outline a small systematic error that occurs in NED because a low-redshift approximation is used when making the correction from redshifts in the heliocentric frame to the cosmic microwave background (CMB) rest frame. It means that historically NED systematically misreported the values of CMB-frame redshifts by up to ∼10−3
z (about 0.001 at redshift of 1). This is a systematic error, and therefore the impact on applications requiring precise redshifts has the potential to be significant—for example, a systematic redshift error of ∼10−4 at low redshift could resolve the Hubble tension. We have consulted with the NED team and they are updating the software to remove this systematic error so these corrections are accurate at all redshifts. Here, we explain the changes and how they impact the redshift values NED currently reports.
Discovery of a Radio Halo (and Relic) in a M
500 < 2 × 1014
M
⊙ Cluster
Authors: Botteon A. , Cassano R. , van Weeren R. J. , Shimwell T. W. , Bonafede A. , Brüggen M. , Brunetti G. , Cuciti V. , Dallacasa D. , de Gasperin F. , Di Gennaro G. , Gastaldello F. , Hoang D. N. , Rossetti M. , Röttgering H. J. A. 
Published: June 2021

Abstract
Radio halos are diffuse synchrotron sources observed in dynamically unrelaxed galaxy clusters. Current observations and models suggest that halos trace turbulent regions in the intracluster medium where mildly relativistic particles are reaccelerated during cluster mergers. Due to the higher luminosities and detection rates with increasing cluster mass, radio halos have been mainly observed in massive systems (

M

500

≳
5
×

10

14

M

⊙

). Here, we report the discovery of a radio halo with a largest linear scale of ≃750 kpc in PSZ2G145.92-12.53 (z = 0.03) using LOw Frequency ARray (LOFAR) observations at 120–168 MHz. With a mass of

M

500

=
(
1.9
±
0.2
)
×

10

14

M

⊙

and a radio power at 150 MHz of

P

150

=
(
3.5
±
0.7
)
×

10

23

W Hz−1, this is the least powerful radio halo in the least massive cluster discovered to date. Additionally, we discover a radio relic with a mildly convex morphology at ∼1.7 Mpc from the cluster center. Our results demonstrate that LOFAR has the potential to detect radio halos even in low-mass clusters, where the expectation to form them is very low (∼5%) based on turbulent reacceleration models. Together with the observation of large samples of clusters, this opens the possibility to constrain the low end of the power–mass relation of radio halos.
Nonequilibrium Ionization Plasma during a Large Solar Limb Flare Observed by Hinode/EIS
Authors: Imada S. 
Published: June 2021

Abstract
This study on plasma heating considers the time-dependent ionization process during a large solar flare on 2017 September 10, observed by Hinode/EUV Imaging Spectrometer (EIS). The observed Fe xxiv/Fe xxiii ratios increase downstream of the reconnection outflow, and they are consistent with the time-dependent ionization effect at a constant electron temperature T

e
= 25 MK. Moreover, this study also shows that the nonthermal velocity, which can be related to the turbulent velocity, reduces significantly along the downstream of the reconnection outflow, even when considering the time-dependent ionization process.