bluuebunny/crossref_metadata_2025_split huggingface dataset:
Role of glutathione S-transferase P1 polymorphism in early transplant complications in patients undergoing allogeneic stem cell transplantation
Authors: Saritas Hazen , Suyani Elif , Güntekin Sezen , Zeynep Aki ahika , Ergün Mehmet Ali , Çelik Bülent , Sucak Gülsan Turkoz 
Published: June 2021

Introduction:
Complications in patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT) cause serious morbidity and mortality. Predicting patients at risk in advance and changing the symptomatic care and/or preparation regimen according to this risk assessment have been emphasized recently. Several single-nucleotide polymorphisms have been studied, and some were found to be responsible for early complications. Glutathione S-transferase P1 (GSTP1) is an enzyme involved in the detoxification process that reduces oxidative stress by reducing the number of free oxygen radicals.

Aim:
This study aimed to investigate the relationship between GSTP1 polymorphism and early complications of allo-HSCT, iron parameters, overall survival (OS), and transplantation-related mortality (TRM).

Materials and Methods:
A total of 50 patients diagnosed with acute myeloid leukemia (n = 23) or acute lymphoblastic leukemia (n = 27) who underwent allo-HSCT between May 2008 and February 2011 at Gazi University Faculty of Medicine, Stem Cell Transplantation Unit, were included.

Results:
Of the 50 patients, 24 (48%) were women and 26 (52%) were men. The median age of the patients was 26 (16–74) years. GSTP1 polymorphism was detected in 23 (46%) patients, and 27 (54%) had no polymorphism (wild type). The two groups were compared in terms of early toxicity after transplantation, according to the preparation regimen. The group with GSTP1 polymorphism was found to have a high transferrin saturation index (P < 0.05). Patients with no GSTP1 polymorphism showed a high grade III–IV anemia ratio (P < 0.05). The presence of sinusoidal obstruction syndrome and graft–versus–host disease was similar in both groups (P > 0.05). OS and TRM were higher in the GSTP1 polymorphism group, but no statistical difference was found between the two groups (P > 0.05).

Conclusions:
TSI was higher in the GSTP1 polymorphism group. GSTP1 polymorphism had no effect on early transplantation complications. Although the OS and TRM ratios were higher in the GSTP1 polymorphism group, no statistically significant difference was found between the groups. Further studies with larger sample size are needed.
Rectal wall sparing effect of a rectal retractor in prostate intensity-modulated radiotherapy
Authors: Ghaffari Hamed , Rostami Aram , Ardekani Mahdieh Afkhami , Mofid Bahram , Mahdavi Seied Rabi 
Published: June 2021

Purpose:
The objective of the study was to evaluate the effectiveness of a rectal retractor (RR) designed to protect rectal tissue in intensity-modulated radiotherapy (IMRT) by pushing rectal wall (RW) away from the prostate.

Materials and Methods:
Twelve patients with localized prostate cancer were enrolled into this study. Patients underwent two computed tomography (CT) scans without and with RR. A prescription of 80 Gy in 40 fractions was planned on CT scans with and without RR. This study evaluates the ability of the RR in RW dose reduction, in particular reduction of the RW V 70Gy≥ 25% in comparison with the plan without RR dose-volume histograms were generated with and without RR. The patient's tolerance was assessed by patient-reported outcomes.

Results:
The planning target volume coverage was equal for both without and with RR (P = 0.155). The mean dose to the RW was statistically significantly lower for the plan with RR than that for the plan without RR, a mean reduction of 5.8 Gy (P = 0.003). Significant relative reductions in rectal dose-volume parameters whether in absolute volume (cc) or as a percentage of contoured RW were detected. A relative reduction more than 25% in RW V70Gy(%) in 100% of patients was achieved. The rectal retraction resulted in a significant increase in the prostate to the rectum space at the prostate midgland level, an absolute increase of 2.7 mm. The retraction of the rectum induced a mean (±standard deviation) pain score of 2.7 (±1.3) according to the visual analog score.

Conclusion:
The application of a RR showed a remarkable rectal sparing effect during prostate IMRT. This may lead to reduced acute and late rectal toxicities in prostate IMRT.
Traction alopecia among adolescents in Keffi, Nasarawa State, Nigeria
Authors: Okoro Obumneme E. , Barminas Rachel A. , Imam Abubakar , Ogunbiyi Adebola O. 
Published: June 2021

Background
Traction alopecia (TA) is common among women of African descent. There is limited information on the etiology and predisposing factors for TA among adolescents in Nigeria. This information is fundamental in changing hair grooming habits, which result in the development of TA in adult women.

Objective
To determine the prevalence, pattern, trichoscopic features, and risk factors for TA among adolescents in Keffi, Nasarawa State, Nigeria.

Patients and methods
This was a cross-sectional study among 333 adolescents selected from secondary schools in Keffi. The students were interviewed to determine their hair care practices and symptoms of TA. The participants were examined for the presence of TA, and trichoscopy was done for those with TA. The data were analyzed using SPSS 25 Statistical software.

Results
The prevalence of TA was 15.1%. The temporal pattern (54.9%) was the commonest pattern. The trichoscopic features were the presence of peripilar casts (45.1%) and perifollicular halos (43.3%). TA was associated with many variables, but the identified risk factors after logistic regression were frequency of relaxing the hair (P=0.022), duration of covering hair (P=0.022), family economic status (P=0.023), and self-reported presence of dandruff (P=0.001).

Conclusion
TA occurs among adolescents in northern Nigeria. Increased frequency of relaxing the hair increases the risk of having TA, whereas the use of head scarfs reduced the chance of acquiring it. Further studies are required to evaluate the effect of hair covers on TA.
Chemical profiling, in vitro antioxidant and antidiabetic assessment of flavonoids from the ethanol extract of Hermannia geniculata root
Authors: Adeniran L.A. , Palanisamy C.P. , Ashafa A.O.T. 
Published: June 2021

Determination of the in vitro antioxidant and the inhibitory potential of flavonoids from Hermannia geniculata (FHG) roots on diabetes-linked enzymes was carried out. The chemical profiling of FHG roots extract was investigated using High Pressure Thin Layer Chromatography (HPTLC) fingerprint analysis. The reactive oxygen scavenging potential of the extract was analyzed. Starch solution (1%) was reacted with different concentrations of FHG extract to determine the α-amylase inhibitory potential of the extract while α- glucosidase inhibition assay was carried out through incubation of different concentrations of the extract followed by addition of p-ntrophenyl-α-Dglucopyranoside solution. HPTLC results indicated the presence of flavonoids/ phenolcarboxylic acid, and Kaemferol (Rf 0.80) were detected in the extract with retention factor Rf. ranging from 0.08 to 0.95. FHG extract showed commendable antioxidant properties with IC50 values (3.07± 0.12, 2.13± 0.67) µg/mL for 1, 1-diphenyl-2- picrylhydrazyl (DPPH) and 2, 2-azino-bis (3- ethylbenzothiazoline-6-sulphonic) acid (ABTS) radicals which were lower and significantly different (p<0.05) compared to standard silymarin with IC50: (3.55± 0.10, 2.77± 0.75) µg/mL for DPPH and ABTS respectively. The results indicated mild inhibition of α-amylase with IC50: (5.55± 0.37) µg/mL which was higher and significantly different (p<0.05) from acarbose with IC50: (3.81± 0.29) µg/mL. Moreover, the extract showed 73% inhibition of α-glucosidase. Kinetic studies of FHG extract revealed competitive and mixed non-competitive inhibition of α- amylase and α-glucosidase respectively. This study indicated FHG capabilities of scavenging reactive oxygen species and reducing hydrolysis of starch responsible for post-prandial hyperglyceamia seen in type 2 diabetes mellitus.
Keywords: Antidiabetic, Antioxidant, Flavonoids, Hermannia geniculate, HPTLC
Mesenteric rent, ileal volvulus and ileocolic intussusception in a 3-year-old large-white dry sow: A postmortem report
Authors: Saleh A. , Fatihu M.Y. , Usman S.G. , Adam M. , Sani N.A. , Abalaka S.E. , Tenuche O.Z. 
Published: June 2021

This report presents a post-mortem (PM) finding of Large-White dry sow which died from complications associated with mesenteric rent, volvulus and intussusception. Other lesions included hydrothorax, ascites, and engorged mesenteric blood vessels, pale and enlarged liver. Helminthological and protozoological examinations of the intestinal samples were negative. Diagnosis of mesenteric rent, ileal volvulus and intussusception was reached. The diagnosis was attributable to the risk factors which include fight, excessive amounts of dry whey concentrate coupled with poor hygiene in the feeding and management system. Familiarizing swine farmers with the symptoms of bowel obstruction and provision of diagnostic facilities in commercial piggery farms will help in facilitating diagnosis and prompt action to prevent mortality and minimize economic loss.
Keywords: Intussusception, Mesenteric rent, Sow, Volvulus, Whey
Phenotypic status of elbow dysplasia in Boerboel dogs in Nigeria
Authors: Ajadi R.A. , Oyenekan I.O. , Alabi M.M. , Makinde O.A. , Ilugbo M.O. , Koleosho S.A. 
Published: June 2021

Elbow dysplasia (ED) is a developmental, multifactorial, polygenic disease of rapidly growing, large breed of dogs. ED can be a significant health concern for affected dogs because treatments are largely ineffective, making selectively breeding of normal dogs the best option for disease control. Despite the relative availability of data on ED prevalence in other breeds, there is dearth of information on ED prevalence in Boerboel dogs. This study evaluated ED prevalence and relative percentages of different ED grades in Boerboel dogs using radiographs of dogs presented for screening between April 2016 and September 2020. Extended latero-medial, flexed latero-medial and cranio-lateral-caudo-medial oblique radiographs from 64 dogs were reviewed. Radiographs were graded using international elbow working group (IEWG) criteria and grades 0-3 assigned to each joint. ED prevalence expressed as percentages were obtained by dividing the number of dogs with grades 1, 2 and 3 by total number of dogs. Age and sex difference in ED prevalence were compared using chi-square test. Differences were considered significant at P ≤ 0.05. Mean age of the dogs was 2.3 ± 0.6 years. Thirty-six (56.3%) dogs were graded as non-dysplastic, while 28(43.7%) were graded as dysplastic, with grade 3 (46.4%) accounting for majority of ED cases. There were no significant (p > 0.05) difference in sex and age prevalence of ED in the breed. In conclusion, ED prevalence in Boerboel dog is high with majority of dogs having severe grade. Widespread phenotypic screening and strict breeding restrictions are recommended| to control the disease in the breed.
Keywords: Boerboel, Dog, Elbow dysplasia, Prevalence, Radiographic screening
Total aerobic and Coliform counts from Oreochromis niloticus obtained from selected farms in Ibadan
Authors: Ogunleye S.C. , Ishola O.O. , Faroyin O.M. , Adedeji O.B. 
Published: June 2021

The environment where fishes are caught often determines their microbial flora, many of which are potential spoilers and not necessarily pathogenic to fishes but are implicated as cause(s) of serious foodborne illnesses and toxin-infections in humans, hence, their presence above permissible levels portends food-safety threats. This study showed the microbial load in Oreochromis niloticus obtained from selected farms in Ibadan, Nigeria. A total of 156 samples consisting of gills, intestines and skins were collected from 52 O. niloticus obtained from Egbeda-(A), Ido-(B), Ibadan-north east-(C) and Ibadan north-west-(D) Local Government Areas of Ibadan for Microbial Load {Total Aerobic Count-(TAC) and Total Coliform Count-(TCC)} enumeration. TAC and TCC were performed using standard methods, and calculated in mean Log Colony Forming Unit ± Standard Deviation (logCFu ± SD). Data were analysed with ANOVA. Overall mean logCFu ± SD TAC and TCC from gills, intestine and skin for the 156 samples were 8.65 ± 0.28 and 6.82 ± 0.20, respectively. Mean TAC 8.64 ± 0.28, 8.69 ± 0.28and 8.62 ± 0.3 and mean TCC 8.69 ± 0.22, 8.66 ± 0.23 and 8.73 ± 0.22 were obtained for gills, intestine and, skin respectively, with p>0.05. Means TAC 8.63 ± 0.36, 8.70 ± 0.20, 8.68 ± 0.33 and 8.56 ± 0.14 and TCC 8.56 ± 0.25, 8.86±0.16, 8.65 ± 0.18and 8.69 ± 0.16 were observed for locations A, B, C, and D respectively with p<0.05 for TAC and p˂0.05. Mean microbial load counts obtained in this study was higher than permissible count of 7 logCFu/mL by International Commission on Microbiological Specification for Foods (ICMSF) for fresh fish, thus, portending public health threats.
Keywords: Oreochromis niloticus, Aerobic bacteria, Enterobacteriacea and Coliforms
Evaluation of changes in spermiogram of Shika Brown® Breeder cocks fed dietary levels of baobab (Adansonia digitata) seedmeal
Authors: Fanaiye O.G. , Okoro L.I. , Shinkut M. , Samuel U.F. , Sinkalu V.O. , Rekwot I.P. 
Published: June 2021

This study evaluated the effects of varying levels of Baobab seed-meal (BSM) on spermiogram of Shika Brown® breeder cocks. Thirty apparently healthy cocks aged 30 weeks with average body weight of 1.78 ± 0.03 kg were used for this study. They were acclimatized and randomly divided into three groups of 10 each. Group A (control), fed 0% BSM growers diet, groups B, (5%) and group C, (10%) BSM diets. Semen samples were collected from each cock twice weekly for 28 days and spermiogram evaluated. Results indicated significant (P< 0.05) difference for mean volume, percentage live spermatozoa, sperm gross motilities and concentration between the treatment groups (B and C) and the control group (A). Mean abnormal sperm of cocks in groups B and C were significantly (P<0.05) lower compared to group A. It was concluded that BSM is likely to improve semen characteristics in breeder cocks. Therefore, it is recommended that BSM at 5% and 10% is safe and should be incorporated into breeder cocks diet by farmers for enhanced semen characteristics.
Keywords: Baobab, Shika Brown®, spermiogram, semen, breeder
Da variação à revelação nas canções de adoniran barbosa
Authors: Da Silva Vera Lúcia Massoni Xavier , Fernandes-Netto Carlos 
Published: June 2021

Nosso interesse pelas canções de Adoniran Barbosa (João Rubinato, Valinhos, SP, 1910 – São Paulo, 1982) surgiu durante as aulas de Sociolinguística, principalmente no que diz respeito ao emprego da variante não padrão nas canções do compositor paulista.
Inquietou-nos, sobremaneira, o comportamento dos alunos de Letras, quando expostos a exemplos de emprego com desvios da língua padrão, uma vez que a grande maioria os considera corruptela, como modo de falar “errado”. Quando questionados sobre gostar ou não gostar de Adoniran, a resposta é afirmativa. Daí, a intenção de verificar o que faz com que suas canções sejam apreciadas e, por que não dizer, cantadas por pessoas ditas cultas e comentadas pela crítica literária, como se depreende das palavras de Antonio Candido (2002):
Convivencia sin violencia en una escuela pública del Perú
Authors: Galindo-Kimura Magaly Analí , Vargas Isabel Menacho , Rueda Edith Mercedes Huertas , Montes Máximo Guillermo Valentín 
Published: June 2021

La investigación fue realizada en torno a la convivencia escolar. A
La investigación fue realizada en torno a la convivencia escolar. Actualmente, los docentes interactúan con un gran porcentaje de estudiantes proceden de hogares carentes de valores donde existen agresiones de toda índole convirtiéndose en cotidiano, lo cual aflora en el aula. Los profesionales desconocen las leyes que protegen a los niños y adolescentes en el sector educación generando que los estudiantes se vean vulnerados. Por tal razón, se busca determinar que tanto mejora la convivencia escolar con una buena gestión desde la propia ley. El estudio se realiza desde un enfoque cuantitativo, tipo básico, diseño descriptivo, de corte transversal. Se buscó conocer los niveles de convivencia sin violencia en una institución escolar pública encontrando como resultado que el 48,3% de docentes mencionan que existe una convivencia democrática, por otro lado, el 45% de docentes señalan que se encuentran en un nivel medio, mientras que el % 6,7 en un nivel bajo.
ctualmente, los docentes interactúan con un gran porcentaje de estudiantes proceden de hogares carentes de valores donde existen agresiones de toda índole convirtiéndose en cotidiano, lo cual aflora en el aula. Los profesionales desconocen las leyes que protegen a los niños y adolescentes en el sector educación generando que los estudiantes se vean vulnerados. Por tal razón, se busca determinar que tanto mejora la convivencia escolar con una buena gestión desde la propia ley. El estudio se realiza desde un enfoque cuantitativo, tipo básico, diseño descriptivo, de corte transversal. Se buscó conocer los niveles de convivencia sin violencia en una institución escolar pública encontrando como resultado que el 48,3% de docentes mencionan que existe una convivencia democrática, por otro lado, el 45% de docentes señalan que se encuentran en un nivel medio, mientras que el % 6,7 en un nivel bajo.
Covid 19 & vertical transmission
Authors: Nayar Kanad Dev , Gupta Shweta , Sanan Sabina , Mehra Preeti , Mishra Jaya , Kant Gaurav , Nayar Kapil Dev 
Published: June 2021

The current coronavirus pandemic is a serious public health emergency and has led to widespread damage globally. Although there are many coronaviruses, the particular that is responsible for this pandemic is the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).It has incubation period of around 2 to 7 days and most symptomatic patients can have fever, malaise, cough, or loss of taste or smell, with some cases developing into life threatening pneumonia and acute respiratory distress syndrome with case fatality rates range from 1% to 2%. Pregnancy is considered as a vulnerable group for any infection and knowledge regarding the possible risk of vertical transmission of this virus is very limited but is important for counseling regarding COVID-19 related pregnancy risks and for further management. COVID 19 infection in mothers basically leads to hypoxia, inflammatory response & cytokine storm. It appears around 10% of SARS- Cov-2 infected pregnant women require hospitalization with respiratory support COVID-19 can infect the placenta as confirmed by the presence of SARSCoV- 2 viral RNA in the placenta and evidence of virions found within the syncytiotrophoblast. The possible neonatal outcomes are increased risk of
English Vocabulary Teaching Techniques at Secondary Level Schools in the Punjab, Pakistan
Authors: Raheem Muhammad Arslan , Asif Mamoona , Latif Mariam , Javed Muhammad Arshad 
Published: June 2021

The aim of the paper was to identify various English vocabulary teaching techniques employed by teachers in public sector. The data for that purpose was collected through classroom observations. A total of 20 classes in various public sector schools of Rahimyar District of the Punjab Pakistan were observed. The majority of the teachers were found employing various techniques to teach their students vocabulary of English Language. It was found that the teachers employed the techniques like visual aids, separate Word lists and rules related to the formation of words to teach students unfamiliar lexical items of English language. The pupils were further asked to memorize the word lists with their synonyms and L1 equivalents so that they may perform better in their academic exams.
KETERPADUAN PROGRAM KOTAKU DALAM PENATAAN PERMUKIMAN KUMUH DI BANTARAN SUNGAI GAJAHWONG
Authors: Nurokhman Nurokhman , Kurniawan Ade 
Published: June 2021

Kota Yogyakarta berkomitmen dalam penanganan kumuh perkotaan sesuai dengan Permen PUPR No 02/PRT/M/2016 Tentang Peningkatan Kualitas Terhadap Perumahan Kumuh dan Permukiman Kumuh yang terdiri dari 7 aspek (kondisi bangunan, jalan, drainase, air minum, persampahan, dan proteksi kebakaran) ditambah 1 aspek ruang terbuka publik yang diatur dalam SE DCJK PUPR No 40/SE/DC/2016. Berdasarkan SK Walikota Yogyakarta No 216 Tahun 2016, Kawasan Warungboto RW007, RW008, dan RW009 merupakan kawasan kumuh dibantaran sungai dengan luas 2,5 Ha. Kondisi kekumuhan di lokasi tersebut pada akhir tahun 2018 sudah mempunyai skor kurang dari 19 yang berarti tidak kumuh. Namun dalam kenyataannya terdapat permasalahan air limbah khusunya permukiman yang berada di tepi bantaran sungai Gajahwong belum memenuhi syarat teknis yaitu umunya dari closed rumah langsung disalurkan ke sungai. Hal ini tentu menjadi permaslahan kesehatan lingkungan dan pencemaran sungai. Tujuan penelitian adalah mengidentifikasi indicator kumuh dan memberikan rekomendasi teknis dalam penataan lingkungan permukiman.
Hasil penelitian menunjukan penanganan kumuh pada Tahun 2017-2018 dengan inetrvensi pekerjaan jalan, drainase dan IPAL Komunal berpengaruh signifikan pada skor kumuh sehingga kondisi akhir tahun 2018 di Warungboto sudah tidak kumuh. Warga terdampak proyek (WTP) langsung terdapat 24 warga yang berada disempadan sungai sejumalh 16 warga sudah melakukan pembongkaran swadaya sedangkan 8 warga bersedia dilakukan pembongkaran dengan dana bantuan program dengan alasan tanahnya sudah SHM. Terdapat 2 kategori pembenahan rumah terdampak dengan konsep M2K (Mundur Mandep Kali) dan M3K (Mundur Munggah Madep kali), namun masih berada di area sempadan sungai karena menurut PERMENPUPR Nomor 28 Tahun 2015 batas sempadan sungai perkotaan yang belum bertanggul lebar minimal 10 m.
Rekomendasinya perlu dibuat peraturan penjelas lebih lanjut dan dilakukan sosialisasi agar terdapat penyamaan persepsi terkait garis sempadan sungai perkotaan dan penataan permukiman yang diperbolehkan. Adanya kesepakatan warga terdampak program yang menyatakan siap untuk ditata perlu diakomodir.
IMPLEMENTASI KEBIJAKAN SMK 3 DI PERUSAHAAN KONTRAKTOR DI YOGYAKARTA
Authors: Machfudiyanto Rossy Armyn , Utomo Danang Priyo 
Published: June 2021

Peningkatan pembangunan di berbagai daerah di Indonesia khususnya di kota Yogyakarta membuat banyak kontaktor saling bersaing dalam melaksanakan sebuah proyek. Mulai dari kecepatan, mutu, dan biaya mereka sangat bersaing dalam 3 hal tersebut. Namun sekarang masih banyak kontraktor yang mengesampingkan Keselamatan dan Kesehatan Kerja (K3) pada proyek konstruksi.
Penelitian ini bertujuan untuk mengetahui identifikasi faktor penerapan SMK3 pada proyek konstruksi dan mengetahui faktor yang dominan pada kelengkapan fasilitas pendukung keselamatan dan kesehatan kerja di proyek
Metode yang digunakan dalam penelitian ini menggunakan metode penelitian kuantitatif dengan cara observasi, metode ini lebih cenderung pada hasil yang deskriptif. Teknik pengambilan sampel dilakukan secara purposive.
Hasil penelitian adalah tingkat implementasi kebijakan sistem manajemen kesehatan dan keselamatan kerja ( SMK3 ) pada perusahaan kontraktor di Yogyakarta rata – rata 69,83% dimana kebijakan pada aspek manusia sebesar 64,78% yang diterapkan, pada aspek peralatan sebesar 72,95% yang diterapkan, pada aspek organisasi sebesar 67,78% yang diterapkan, pada aspek manajemen sebesar 69,42% yang diterapkan, pada aspek lingkungan sebesar 74,22% yang diterapkan.