bluuebunny/crossref_metadata_2025_split huggingface dataset:
Convalescent Plasma Efficacy in Life-Threatening COVID-19 Patients Admitted to the ICU: A Retrospective Cohort Study
Authors: Abuzakouk Mohamed , Saleh Khaled , Algora Manuel , Nusair Ahmad , Alameri Jawahir , Alshehhi Fatema , Alkhaja Sara , Badr Mohamed , Abdallah Khaled , De Oliveira Bruno , Nadeem Ashraf , Varghese Yeldho , Munde Dnyaseshwar , Salam Shameen , Abduljawad Baraa , Elkambergy Hussam , Wahla Ali , Taha Ahmed , Dibu Jamil , Bayrlee Ahmed , Hamed Fadi , AbdelWareth Laila , Rahman Nadeem , Guzman Jorge , Mallat Jihad 
Published: May 2021

(1) Background: There are limited data regarding the efficacy of convalescent plasma (CP) in critically ill patients admitted to the intensive care unit (ICU) due to coronavirus disease 2019 (COVID-19). We aimed to determine whether CP is associated with better clinical outcome among these patients. (2) Methods: A retrospective single-center study including adult patients with laboratory-confirmed SARS-CoV-2 infection admitted to the ICU for acute respiratory failure. The primary outcome was time to clinical improvement, within 28 days, defined as patient discharged alive or reduction of 2 points on a 6-point disease severity scale. (3) Results: Overall, 110 COVID-19 patients were admitted. Thirty-two patients (29%) received CP; among them, 62.5% received at least one CP with high neutralizing antibody titers (≥1:160). Clinical improvement occurred within 28 days in 14 patients (43.7%) of the CP group vs. 48 patients (61.5%) in the non-CP group (hazard ratio (HR): 0.75 (95% CI: 0.41–1.37), p = 0.35). After adjusting for potential confounding factors, CP was not independently associated with time to clinical improvement (HR: 0.53 (95% CI: 0.23–1.22), p = 0.14). Additionally, the average treatment effects of CP, calculated using the inverse probability weights (IPW), was not associated with the primary outcome (−0.14 days (95% CI: −3.19–2.91 days), p = 0.93). Hospital mortality did not differ between CP and non-CP groups (31.2% vs. 19.2%, p = 0.17, respectively). Comparing CP with high neutralizing antibody titers to the other group yielded the same findings. (4) Conclusions: In this study of life-threatening COVID-19 patients, CP was not associated with time to clinical improvement within 28 days, or hospital mortality.
Modelo matemático para el control de costos de empresas productivas
Authors: Solares Gantier María Pamela 
Published: May 2021

Uno de los problemas que atraviesan las empresas y organizaciones productivas de Bolivia es el control de costos, en especial los costos indirectos que son los más difíciles de administrar. El objetivo de esta investigación fue desarrollar un modelo matemático que permita identificar los costos que reducen las utilidades.
La metodología utilizada identificó las causas, como los costos directos e indirectos para llegar al efecto, representado como Costo Unitario Total, resultando un modelo multivariable y multifactorial.
Los resultados de la simulación muestran en la información final productos con alta y baja utilidad y, en algunos casos, con valores negativos, validando el modelo. Existen beneficios materiales y cualitativos que resultan de la aplicación del Modelo, por lo que se considera recomendable ejercitar su implantación en toda empresa que pretenda obtener mayores utilidades con la mejor utilización de sus recursos humanos y materiales.
Study regarding the motivational differences of professional athletes
Authors: Ababei Radu 
Published: May 2021

The subject of motivation in sports is a widely debated one in the professional literature, either by psychologists or by coaches, most of the times stopping at the identification of the main markers that favor or hurt top performance.The purpose variable in relation to the nature and aim of the sport, and to the motivation, where the results were almost identical. This study provides information regarding the reaching of motivational goals by individual and team sports athletes, by highlighting the components that will allow the athletes to face the negative psychological states successfully and to be able to express their peak performance ability.For this study, a group of 86 male athletes were selected, aged 18-25, divided into two groups, one for individual sports and one for team sports. The hypothesis was that there are not any significant differences between the individual and team sports athletes in regards to motivation.
Effectiveness of physical therapy interventions for children with cerebral palsy
Authors: Crăciun M. D. , Midrigan N. 
Published: May 2021

Cerebral palsy (CP) describes a group of permanent disorders of motor development and posture that cause limiting activity that are attributed to non-progressive dysfunctions occurring in the development of fetal brain or of the child.The main purpose of the paper is to study the clinical and functional aspects with implications in the design and evaluation of the complex recovery therapy of the child with psycho-neuro-motor disabilities diagnosed with infantile cerebral palsy (ICP).The study took place during the period June 2016 - March 2018, is of the type prospectively and comprised 5 children diagnosed with ICP, aged 4 to 12 years. Criteria for inclusion in the recovery group: children diagnosed with infantile cerebral palsy form spastic tetra- spastic, without orthopedic surgery, during the study period. Children have been given a comprehensive assessment of body attitude, upper and lower limb hypertonia, upper limbs functionality, and global motor function.The major objective of recovering the child with infantile cerebral palsy was to improve the quality of life by creating conditions for minimum patient autonomy. The functional recovery program was carried out three times a week using exercises and methods of neuro-motor rehabilitation. Duration of the session was 50-60 min.Due to the results obtained at the initial and final evaluation, a tonus improvement was observed in all the tested muscles, with a decrease in the mobilization resistance of all the muscle groups. In global functional evaluation the total score on the 5 sections of the 5 children with CP had an initial mean value of 34.92 (± 16.60) and a final of 47.72 (± 26.53)Stretching, neuro-motor reeducation methods and active physical exercises help to increase the degree of the functional independence.
Impact of quarantine, due to COVID-19, on physical activity, monitored with EEG
Authors: Bastiurea Eugen , Stan Zenovia 
Published: May 2021

Due to the situation created by the emergence of Covid-19, we found that the restrictions and quarantine had a significant effect on normal activities and especially on physical activities. Physical education teachers, coaches, sports instructors, etc., were forced to change the approach of this segment of activity, from all points of view. As the promotion of physical activity has become a global priority, leading to a drastic review of this field, we used the most advanced study methods to establish the effects of quarantine and motor activities at home on brain activity.Electroencephalogram (EEG) is a method that records electrical activity on the scalp and measures voltage changes resulting from ionic current flows in brain neurons. In this case study, we monitored the EEG activity of a Pilates instructor also the manifestation of brain waves (Delta, Theta, Alpha, Beta and Gamma) during specific activities during quarantine. We assumed that this forced adaptation to indoor activity will lead to certain manifestations of the brain waves depending on the specifics of the activities (theoretical training, physical training and online teaching Pilates sessions) and will be influenced by the extension of the quarantine period.
Study on the appreciation of the level of physical condition in adults
Authors: Scurt Corneliu 
Published: May 2021

The research hypothesis is based on the assumption that the factors of the physical condition under evaluation are in accordance with the level of growth and development of the tested subjects. The object of the research is the model of physical condition of the students from the final year of FPEMS. The purpose of the research is the continuous improvement and guidance of the content of the preparatory lessons in order to maintain an optimal level of physical condition, necessary to fulfil the requirements of the school program. The practical value of the research consists in the possibility to elaborate training models, by allowing the specialists to select the most effective factors that influence the level of physical condition.
Practical aspects regarding the relief of back pain with the thermal massage bed
Authors: Stan Zenovia , Bastiurea Eugen 
Published: May 2021

The beneficial effects of massage beds and massage chairs are well known. They are more and more complex but also more accessible for the population. In this study, we showed the possibility of introducing the Ceragem massage bed in multidisciplinary programs for pain relief and recovery from back diseases. Although massage beds are frequently used all over the world, they are generally used only for relaxation and there are not many specialized studies that provide details about concrete ways of their use. In this study, we presented some general practical aspects regarding the use of this device and a synthesis of its efficiency of integration in physical activity sessions. We made observations during 40 months (2017-2020) over 3600 sessions in which we used the massage bed. These conclusions must be accepted with caution, because they concern only this group of subjects and the study carried out in the specific conditions of adapted motor activities.
A low power L-shaped gate bipolar impact ionization MOSFET based capacitorless one transistor dynamic random access memory cell
Authors: Kumar Kamal Alok , Kamal Neha , Singh Jawar 
Published: May 2021

Abstract
In this paper, a capacitorless, low power and CMOS compatible L-shaped gate bipolar impact ionization metal-oxide semiconductor (L-BIMOS) one transistor dynamic random access memory (1T DRAM) cell is proposed. The proposed 1T DRAM offers high retention time (RT = ∼1.4 s), sense margin (SM = ∼45 μA μm−1) and read current ratio (∼5 orders of magnitude). The RT and SM are 1.86×, and 300× , respectively higher than the previously reported silicon germanium (SiGe) based BIMOS 1T DRAM. Therefore, the proposed 1T DRAM cell stands out to be power efficient, and provides better integration density that makes it suitable for various emerging computing applications.
Analysis of dissolution kinetics of narrow polydispersity poly(4-hydroxystyrene) in alkaline aqueous solution using machine learning
Authors: Tanaka Naoki , Watanabe Kyoko , Matsuoka Kyoko , Azumagawa Kazuki , Kozawa Takahiro , Ikeda Takuya , Komuro Yoshitaka , Kawana Daisuke 
Published: May 2021

Abstract
Understanding the dissolution kinetics of resist materials is essential for their efficient development. In this study, we investigated the dissolution kinetics of poly(4-hydroxystyrene) (PHS) with a weight-average molecular weight (M
w) of 8000–30 000 and a polydispersity index (M
w
/M
n) of 1.07–1.20. The dissolution kinetics of PHS films was observed in tetramethylammonium hydroxide (TMAH) aqueous developers by a quartz crystal microbalance (QCM) method. The TMAH concentration was changed from 0 to 2.38 wt%. The formation of a thick transient swelling layer at these M
w
/M
n values was suppressed compared with that at M
w
/M
n > 2. QCM data were analyzed using the polynomial regression to clarify the effects of M
w and M
w
/M
n on the dissolution kinetics in a narrow polydispersity region. Both dissolving and swelling kinetics largely depended on M
w/M
n. M
w had little effect in 2.38 wt% TMAH developer; however, it had a large effect on the swelling when 2.38 wt% TMAH developer was diluted.
Escritas literárias africanas
Authors: Da Silva Cristina Maria , Taborda Terezinha 
Published: May 2021

A presente proposta visa reunir trabalhos em torno da temática Memórias de Guerra em Experiências Literárias Africanas e de como a escrita tem elaborado traumas coletivos. Evocando noções como narrativa, trajetórias e memória, pensamos que é possível observar como os processos de recordação e elaboração têm se construído através da escrita literária. O que essas narrativas mobilizam de suas paisagens coletivas? como narram os enfrentamentos e as consequências da guerra civil? como se esboçam nessas narrativas as trajetórias desses escritores, de seus países e de seus repertórios culturais? Enfim, como são mobilizados em suas escritas as recordações. Que espaços da recordação são mobilizados na montagem de suas escrituras? A memória do trauma é uma forma de recuperar na fragilidade dos rastros individuais a compreensão para a história e para as condições socioantropológicas de cada sociedade. Propomos reunir, neste Dossiê, reflexões que ponham em diálogo preocupações do campo das ciências humanas, sociais e literárias que nos permitam refletir sobre essas experiências nas literaturas africanas.
Talent transfer: A systematic review
Authors: Van Harten Karlijn , Bool Kayan , Van Vlijmen Janiek , Elferink-Gemser Marije 
Published: May 2021

Background: The effectiveness of traditional talent development (TD) programs can be questioned. Meanwhile, an extra pathway to the top has made its appearance: Talent transfer (TT). The aim of TT is to fast-track talented athletes into the high-performance environment. The first TT initiatives and studies exploring the TT process have been carried out.
Objective: This systematic review gives an overview of studies examining TT, by situating TT within the developmental framework, comparing formal and informal TT and investigating the similarities between donor and transfer sports in TT from elite and non-elite level.
Methods: A search was conducted on the PubMed and PsychINFO databases. The analysis was done according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta Analyses) statement.
Results: After screening on title and abstract and full-text review, five studies remained for inclusion. Although literature is still scarce, results show that TT can serve as an alternative pathway in addition to the traditional TD programs. Literature suggests that similarities between donor and transfer sports are helpful, but this is not a prerequisite for TT. Besides, psychological factors are perceived to play an important role. Results regarding other determining factors of TT are still lacking. Athletes, national governing bodies and TD programs might benefit from this additional pathway, but the effectiveness of formal and informal TT remains unclear.
Conclusion: A lot remains unknown about TT, hence future research is needed to increase our understanding of TT and its contribution as an extra pathway to the top.
Terminus: A Versatile Simulator for Space-based Telescopes
Authors: Edwards Billy , Stotesbury Ian 
Published: May 2021

Abstract
Space-based telescopes offer unparalleled opportunities for characterizing exoplanets, solar system bodies, and stellar objects. However, observatories in low-Earth orbits (e.g., Hubble, CHaracterising ExOPlanets Satellite, Twinkle, and an ever-increasing number of cubesats) cannot always be continuously pointed at a target due to Earth obscuration. For exoplanet observations consisting of transit, or eclipse, spectroscopy, this causes gaps in the light curve, which reduces the information content and can diminish the science return of the observation. Terminus, a time-domain simulator, has been developed to model the occurrence of these gaps to predict the potential impact on future observations. The simulator is capable of radiometrically modeling exoplanet observations as well as producing light curves and spectra. Here, Terminus is baselined on the Twinkle mission, but the model can be adapted for any space-based telescope and is especially applicable to those in a low-Earth orbit. Terminus also has the capability to model observations of other targets such as asteroids or brown dwarfs.
Experiencias de formación y producción cultural en cárceles de Argentina: una reflexión sobre el Programa de Extensión en Cárceles.
Authors: Bustelo Cynthia Ethel 
Published: May 2021

Este trabajo presenta, describe y analiza la experiencia de formación y producción cultural llevada a cabo desde el Programa de Extensión en Cárceles (PEC), dependiente de la Secretaría de Extensión Universitaria y Bienestar Estudiantil (SEUBE) de la Facultad de Filosofía y Letras (FFyL) de la Universidad de Buenos Aires (UBA). Las estrategias y acciones llevadas adelante por el programa, están orientadas a construir herramientas y oportunidades para la inclusión social de las personas privadas de libertad y liberadas, y promover la defensa de los derechos humanos. Propongo poner a disposición las líneas de acción y reflexión que llevamos a cabo, recuperar los procesos de elaboración y puesta en marcha de las propuestas y las fundamentaciones pedagógicas, epistemológicas, políticas que sustentan nuestra tarea. El trabajo tiene por desafío explorar las posibilidades y límites para construir un corpus pedagógico y sensible, desde mi propia voz de docente, coordinadora e investigadora.
Characterizations of Morrey type spaces
Authors: Sun Fangmei , Wulan Hasi 
Published: May 2021

AbstractFor a nondecreasing function
$K: [0, \infty)\rightarrow [0, \infty)$
and
$0<s<\infty $
, we introduce a Morrey type space of functions analytic in the unit disk
$\mathbb {D}$
, denoted by
$\mathcal {D}^s_K$
. Some characterizations of
$\mathcal {D}^s_K$
are obtained in terms of K-Carleson measures. A relationship between two spaces
$\mathcal {D}^{s_1}_K$
and
$\mathcal {D}^{s_2}_K$
is given by fractional order derivatives. As an extension of some known results, for a positive Borel measure
$\mu $
on
$\mathbb {D}$
, we find sufficient or necessary condition for the embedding map
$I: \mathcal {D}^{s}_{K}\mapsto \mathcal {T}^s_{K}(\mu)$
to be bounded.
Quantification of carbon dioxide released from effervescent granules as a predictor of formulation quality using modified Chittick apparatus
Authors: Arshad Muhammad Sohail , Sedhain Kabindra , Hussain Amjad , Abbas Nasir , Mudassir Jahanzeb , Mehmood Faisal , Irfan Muhammad , Latif Sumera 
Published: May 2021

Purpose: To develop a method for the measurement of carbon dioxide (CO2) released from effervescent formulations.
Methods: Effervescent granules were prepared using sodium bicarbonate and citric acid by fusion and solvent-assisted granulation methods. The amount of CO2 released was determined from the maximum pressure of gas release, time profile of pressure gradient using modified Chittick apparatus and gravimetric changes following effervescence.
Results: The amount of CO2 released from effervescent granules prepared by fusion method was 8.125, 8.763 and 7.98 mM/g measured by ideal gas equation, pressure gradient and gravimetric method, respectively. The formulation prepared by solvent-assisted granulation showed 5.525, 5.475 5.36 mM/g of carbon dioxide measured by the above three methods, respectively. The effervescent granules prepared by fusion method showed approximately 2 % loss in effervescence. However, approximately 39 % loss in effervescence was observed for the formulation prepared by solventassisted granulation. The commercial products showed a loss in effervescence in the range of 5 - 15%.
Conclusion: Modified Chittick’s apparatus is a useful analytical tool for monitoring of the CO2 from effervescent granules as a function of method of preparation.
Cavidine protects against asthma in neonatal asthmatic mice model by attenuating PI3Ks/NF-κB signaling pathway
Authors: Hao Qin , Shen Juan , Zhao Lin 
Published: May 2021

Purpose: To evaluate the protective effect of cavidine against asthma in neonatal mice.
Methods: Neonatal mice were treated with cavidine at doses of 5 and 10 mg/kg, po, 2 h prior to asthma induction with ovalbumin (OVA) on the 1st and 14th days of the treatment protocol. The anti-asthma activity of cavidine was evaluated by determining the number of inflammatory cells and cytokine levels in broncho-alveolar lavage fluid (BALF) and OVA-specific IgE and TGF-β 1 in the serum of OVAsensitized mice. The levels of NF-ƙB and PI3K protein expression were determined in the lung tissues of OVA-sensitized mice.
Results: Cavidine attenuated the number of inflammatory cells and cytokines in BALF of OVAsensitized mice. The levels of OVA-specific IgE and TGF-β 1 decreased significantly in cavidine-treated groups, when compared to asthmatic group of mice, while NF-ƙB was significantly downregulated (p < 0.01). The altered expression of PI3K signaling protein was attenuated in the lung tissues of cavidinetreated mice sensitized with OVA.
Conclusion: These results reveal that the anti-asthma effect of cavidine in OVA-induced asthmatic neonatal mice occurs via reduction of inflammation and immune responsive cells linked to PI3Ks/ NF-κB signaling pathway in lung tissues. These findings suggest that cavidine may be clinically suitable for the management of asthma.
Astragaloside IV exerts anti-inflammatory role in endometriosis by downregulating TLR4/NF-κB pathway
Authors: Zhang Yongping , Huang Ouping , Zhang Wei , Liu Luxin , Xu Caiwei 
Published: May 2021

Purpose: To investigate the effect of astragaloside IV administration on the inflammatory response in endometriosis and the underlying mechanism of action.
Methods: Mice were divided into two groups: endometriosis (EMs) mice and control mice (n = 12). EMs induction in mice was achieved by transplantation of mouse uterine tissue. The same procedure was performed in control mice except that a separate suture was inserted instead of endometrial tissue. After 5 weeks, EMs mice were treated with or without astragaloside IV (AIV). The tissue lesions in EMs and control mice were stained with hematoxylin and eosin staining. The activation of toll-like receptor 4 (TLR4) and nuclear factor-κB (NF-κB) p65 signaling was evaluated by western blot, while expression of inflammatory cytokines was evaluated by quantitative real-time-polymerase chain reaction (qRT-PCR), and enzyme-linked immunosorbent assay (ELISA).
Results: Astragaloside IV repressed the inflammation of murine Ems lesions, and also dampened the activation of TLR4/NF-κB signaling in vivo and vitro (p < 0.01 and p < 0.001, respectively). In addition, the expression levels of inflammatory cytokines (IL-1β, IL-6, Ccl-2, and TNF-α) decreased following AIV treatment in vivo.
Conclusion: The results indicate that TLR4/NF-κB signaling pathways are closely related to the inhibition of Ems inflammation by astragaloside IV. Thus, astragaloside IV may be a novel drug for the prevention and treatment of endometrioses.