bluuebunny/crossref_metadata_2025_split huggingface dataset:
LEITURAS DO CERRADO E DA VIDA NO CONTO “SUA ALMA, SUA PALMA” DE BERNARDO ÉLIS
Authors: Paiva Divina Pinto 
Published: December 2021

Este ensaio tem por objetivo, ler aspectos peculiares do sertão apresentado por Bernardo Élis no conto “Sua Alma, sua palma”. Propomos, via teorias das linguísticas do texto – algumas leituras em semioses – focando caminhos de gente com destinos fragmentados e estilhaçados, no oco desse serTÃO. Pessoas TÃO gananciosas, mesquinhas, desonestas, covardes, sem escrúpulos em escritas vivas: MI-SE-RÁ-VEIS. Gente é bicho? Distribuímos, no corpo do ensaio, trechos do conto em estudo para serem lidos a partir de trechos recortados das teorias dos autores que recorremos para a sustentação dos nossos modos de ler e de dizer sobre “Sua Alma, sua palma”. O conto é dividido em três partes marcadas por espaçafação dupla. Pressupomos serem esses vãos recursos utilizados pelo autor para marcar o tempo como se este fosse também vau que dá passagem de uma parte para a outra das histórias narradas. Assim, de território a território, as linguagens verbal e não verbal, abrigam possibilidades de leituras, e, nelas, eu me almo em novas aprendizagens. A vida ainda hoje, está atrelada às situações de natureza hostil e inóspita.
Palavras-Chave. Leituras. Gêneros textuais. O cerrado e o garimpo. A vida e a morte.
OS MESMOS BECOS, OUTROS OLHOS
Authors: Barbosa Wanderson Alves 
Published: December 2021

Este artigo apresentara um estudo da relação da obra poética do escritor Bernardo Élis com as mais diversas histórias, memórias e manifestações da Cidade de Goiás. Trataremos dessa cidade tão cantada nos versos do escritor com foco em toda geograficidade poética que desprende dela e dos seus habitantes. Emoções sentimentos e poesia nos acompanham nesse trabalho que discute poemas de “Primeira Chuva”, única obra poética desse autor, nele buscamos dialogar com a obra numa perspectiva fenomenológica, fazendo links com teóricos que discutem geograficidade e poesia, traçando assim uma ponte entre a realidade dessa incrível cidade goiana e suas diversas representações na escrita poética desse consagrado autor goiano.
Palavras chave. Cidade de Goiás, literatura, geografia, poesia, Bernardo Élis.
Surgery for intramedullary spinal cord ependymomas in the neuromonitoring era: results from a consecutive series of 100 patients
Authors: Skrap Benjamin , Tramontano Vincenzo , Faccioli Franco , Meglio Mario , Pinna Giampietro , Sala Francesco 
Published: December 2021

OBJECTIVE
The established treatment of intramedullary spinal cord ependymomas (ISCEs) is resection. Surgical series reporting treatment results often lack homogeneity, as these are collected over long time spans and their analysis is plagued by surgical learning curves and inconsistent use of intraoperative neurophysiological monitoring (IONM). The authors report the oncological and functional long-term outcomes in a modern series of 100 consecutive ISCEs that were resected between 2000 and 2015 by a surgically experienced team that consistently utilized IONM.

METHODS
In this retrospective study, the authors tailored surgical strategy and multimodal IONM, including somatosensory evoked potentials, muscle motor evoked potentials (mMEPs), and D-waves, with the aim of gross-total resection (GTR). Preservation of the D-wave was the primary objective, and preservation of mMEPs was the second functional objective. Functional status was evaluated using the modified McCormick Scale (MMS) preoperatively, postoperatively, and at follow-up.

RESULTS
Preoperatively, 89 patients were functionally independent (MMS grade I or II). A GTR was achieved in 89 patients, 10 patients had a stable residual, and 1 patient underwent reoperation for tumor progression. At a mean follow-up of 65.4 months, 82 patients were functionally independent, and 11 lost their functional independence after surgery (MMS grades III–V). Muscle MEP loss predicted short-term postoperative worsening (p < 0.0001) only, while the strongest predictors of a good functional long-term outcome were lower preoperative MMS grades (p < 0.0001) and D-wave preservation. D-wave monitorability was 67%; it was higher with lower preoperative MMS grades and predicted a better recovery (p = 0.01).

CONCLUSIONS
In this large series of ISCEs, a high rate of GTR and long-term favorable functional outcome were achieved. Short- and long-term functional outcomes were best reflected by mMEPs and D-wave monitoring, respectively.
Long-term functional outcome of surgical treatment for degenerative cervical myelopathy
Authors: Dijkman Mark D. , van Bilsen Martine W. T. , Fehlings Michael G. , Bartels Ronald H. M. A. 
Published: December 2021

OBJECTIVE
Degenerative cervical myelopathy (DCM) is a major global cause of spinal cord dysfunction. Surgical treatment is considered a safe and effective way to improve functional outcome, although information about long-term functional outcome remains scarce despite increasing longevity. The objective of this study was to describe functional outcome 10 years after surgery for DCM.

METHODS
A prospective observational cohort study was undertaken in a university-affiliated neurosurgery department. All patients who underwent surgery for DCM between 2008 and 2010 as part of the multicenter Cervical Spondylotic Myelopathy International trial were included. Participants were approached for additional virtual assessment 10 years after surgery. Functional outcome was assessed according to the modified Japanese Orthopaedic Association (mJOA; scores 0–18) score at baseline and 1, 2, and 10 years after surgery. The minimal clinically important difference was defined as 1-, 2-, or 3-point improvement for mild, moderate, and severe myelopathy, respectively. Outcome was considered durable when stabilization or improvement after 2 years was maintained at 10 years. Self-evaluated effect of surgery was assessed using a 4-point Likert-like scale. Demographic, clinical, and surgical data were compared between groups that worsened and improved or remained stable using descriptive statistics. Functional outcome was compared between various time points during follow-up with linear mixed models.

RESULTS
Of the 42 originally included patients, 37 participated at follow-up (11.9% loss to follow-up, 100% response rate). The mean patient age was 56.1 years, and 42.9% of patients were female. Surgical approaches were anterior (76.2%), posterior (21.4%), or posterior with fusion (2.4%). The mean follow-up was 10.8 years (range 10–12 years). The mean mJOA score increased significantly from 13.1 (SD 2.3) at baseline to 14.2 (SD 3.3) at 10 years (p = 0.01). A minimal clinically important difference was achieved in 54.1%, and stabilization of functional status was maintained in 75.0% in the long term. Patients who worsened were older (median 63 vs 52 years, p < 0.01) and had more comorbidities (70.0% vs 25.9%, p < 0.01). A beneficial effect of surgery was self-reported by 78.3% of patients.

CONCLUSIONS
Surgical treatment for DCM results in satisfactory improvement of functional outcome that is maintained at 10-year follow-up.
Patient preferences for treatment of lumbar disc herniation: a discrete choice experiment
Authors: Gadjradj Pravesh S. , Smeele Nicholas V. R. , de Jong Mandy , Depauw Paul R. A. M. , van Tulder Maurits W. , de Bekker-Grob Esther W. , Harhangi Biswadjiet S. 
Published: December 2021

OBJECTIVE
Lumbar discectomy is a frequently performed procedure to treat sciatica caused by lumbar disc herniation. Multiple surgical techniques are available, and the popularity of minimally invasive surgical techniques is increasing worldwide. Clinical outcomes between these techniques may not show any substantial differences. As lumbar discectomy is an elective procedure, patients’ own preferences play an important role in determining the procedure they will undergo. The aims of the current study were to determine the relative preference weights patients apply to various attributes of lumbar discectomy, determine if patient preferences change after surgery, identify preference heterogeneity for choosing surgery for sciatica, and calculate patient willingness to pay for other attributes.

METHODS
A discrete choice experiment (DCE) was conducted among patients with sciatica caused by lumbar disc herniation. A questionnaire was administered to patients before they underwent surgery and to an independent sample of patients who had already undergone surgery. The DCE required patients to choose between two surgical techniques or to opt out from 12 choice sets with alternating characteristic levels: waiting time for surgery, out-of-pocket costs, size of the scar, need of general anesthesia, need for hospitalization, effect on leg pain, and duration of the recovery period.

RESULTS
A total of 287 patients were included in the DCE analysis. All attributes, except scar size, had a significant influence on the overall preferences of patients. The effect on leg pain was the most important characteristic in the decision for a surgical procedure (by 44.8%). The potential out-of-pocket costs for the procedure (28.8%), the wait time (12.8%), need for general anesthesia (7.5%), need for hospitalization (4.3%), and the recovery period (1.8%) followed. Preferences were independent of the scores on patient-reported outcome measures and baseline characteristics. Three latent classes could be identified with specific preference patterns. Willingness-to-pay was the highest for effectiveness on leg pain, with patients willing to pay €3133 for a treatment that has a 90% effectiveness instead of 70%.

CONCLUSIONS
Effect on leg pain is the most important factor for patients in deciding to undergo surgery for sciatica. Not all proposed advantages of minimally invasive spine surgery (e.g., size of the scar, no need of general anesthesia) are necessarily perceived as advantages by patients. Spine surgeons should propose surgical techniques for sciatica, not only based on own ability and proposed eligibility, but also based on patient preferences as is part of shared decision making.
Analysis of the beryllium stability under standard and critical operation in a fusion reactor
Authors: Bekbayev K. , Akim M. , Nabiyeva Zh. 
Published: December 2021

Currently, dark fermentation is the most practically applicable for the implementation of biotechnological roduction of hydrogen. However, this process has certain limiting factors, since a significant part of the substrates are converted into various metabolic products, but not into H2 . Therefore, it is necessary to develop optimal conditions for energy recovery in the form of gaseous molecular hydrogen. Various carbohydrate-containing raw materials for hydrogen production often require pretreatment before they can be used by microorganisms. Dilute acid pretreatment represents a promising way to increase biohydrogen production. However, during acid hydrolysis of carbohydrate-containing wastes, in addition to the released soluble sugars, inhibitors of enzymatic processing, such as furfural and 5-HMF, acetic and propionic acids, etc., can accumulate. In this regard, it is necessary to select the optimal conditions for the efficient production of biohydrogen. This study investigated the production of biohydrogen during the microbial fermentation of sugars in a dilute solution of a molasses-based acid hydrolyzate using Escherichia coli and a multiple mutant. The results of the experiments showed that molasses is a valuable product as a source of carbon and energy for microorganisms in the production of biohydrogen, as well as for the production of biomass for the further production of various products with high added value.
ASSESSMENT OF THE CORRELATION BETWEEN FAMILY BURDEN IN PRIMARY CAREGIVERS AND DISABILITY IN PATIENTS WITH SCHIZOPHRENIA
Authors: K Ronald Roy , Tharmaraja Abinaya 
Published: December 2021

Background: Schizophrenia is one of the most devastating, and a chronic, relapsing mental illness associated with increased morbidity, poor quality of life and low recovery rates. In India, families are the major providers of long-term care and they represent an important supportive, social network for patients with schizophrenia. Indian families experience significant degrees of burden in the care of their relatives with schizophrenia. Illness severity and patients' disability have a direct positive relationship with perceived family burden.
Methods: This study is a cross-sectional study, done to assess the correlation between family burden in primary caregivers and disability in patients with schizophrenia. 60 patients with schizophrenia and their primary caregivers were recruited from the outpatient and inpatient units of Department of Psychiatry, Government Rajaji Hospital, Madurai. IDEAS (Indian Disability Evaluation Assessment Scale) scale was used to assess the disability of patients with schizophrenia and BAS (Burden Assessment Schedule) of SCARF (Schizophrenia Research Foundation) was used to assess the family burden in their primary caregivers.
Results: Among the 60 primary caregivers, (48.3%) were having caregiver burden between 50 and 70%. (56.4%) of female caregivers had burden range 50- 70%. (56.5%) of caregivers delivering care for patients with illness between 15 and 20 years experienced burden >70%. Statistical analysis revealed that the correlation between caregiver burden and disability was statistically significant.
Conclusions: The severity of caregiver burden increases with increasing grades of disability and indicates that caregiver burden affects the overall outcome of schizophrenia
Keywords: Schizophrenia, Caregiver burden, Disability, Outcome
SATISFACTION OF SUSPECTED COVID-19 PATIENTS REGARDING MEAL SERVICES AT A TERTIARY CARE HOSPITAL OF NORTH INDIA
Authors: Talati Shweta , Sethi Saru , Mohindra Ritin , Arora Pankaj , Dhaliwal Navneet , Malhotra Sunita , Soni Roop Kishor , Gupta A.K. 
Published: December 2021

Introduction: Meal services plays a significant role in speedy recovery and increases patient satisfaction.
Objective: Present study was done to assess the satisfaction of suspected COVID-19 patients regarding meal services at a tertiary care hospital of north India.
Methodology: This cross-sectional study in retrospective design was done to understand the factors affecting the satisfaction of suspected COVID-19 patients with respect to meal services. The data was collected for patients admitted from January 2020-June 2020 with the help of a questionnaire with graded responses i.e Yes, No or Maybe/Not applicable, gathered from participants after discharge from hospital through ‘google forms’.
Results: Out of 160 participants, 159 filled up the questionnaire through ‘google form’. Majority of the participants were <30 Years old 46.5%, had university or higher education 52.8%. The study showed 96.9% patients were satisfied and 3.1% were not satisfied with the quality of the meal services provided during the hospital stay. There was no significant association observed between taste of meals and consumption of whole meal with the quality of the meal served (p = 0.875, p = 0.855 respectively). Although significant association was observed between temperature of meal, time of meal distribution, quantity of water bottles provided, and quality of meal served (p = 0.000, p = <0.001, p = 0.000).
Conclusion: Present study connotes that such types of assessments can help identify the gaps which can be worked on for achieving maximal satisfaction of patients with respect to quality of meal services in the hospital.
Key words: COVID-19 patients; Meal services; Patient Satisfaction; Tertiary care hospital
Radiomics Analysis Derived From LGE-MRI Predict Sudden Cardiac Death in Participants With Hypertrophic Cardiomyopathy
Authors: Wang Jie , Bravo Laura , Zhang Jinquan , Liu Wen , Wan Ke , Sun Jiayu , Zhu Yanjie , Han Yuchi , Gkoutos Georgios V. , Chen Yucheng 
Published: December 2021

Objectives: To identify significant radiomics features derived from late gadolinium enhancement (LGE) images in participants with hypertrophic cardiomyopathy (HCM) and assess their prognostic value in predicting sudden cardiac death (SCD) endpoint.Method: The 157 radiomic features of 379 sequential participants with HCM who underwent cardiovascular magnetic resonance imaging (MRI) were extracted. CoxNet (Least Absolute Shrinkage and Selection Operator (LASSO) and Elastic Net) and Random Forest models were applied to optimize feature selection for the SCD risk prediction and cross-validation was performed.Results: During a median follow-up of 29 months (interquartile range, 20–42 months), 27 participants with HCM experienced SCD events. Cox analysis revealed that two selected features, local binary patterns (LBP) (19) (hazard ratio (HR), 1.028, 95% CI: 1.032–1.134; P = 0.001) and Moment (1) (HR, 1.212, 95%CI: 1.032–1.423; P = 0.02) provided significant prognostic value to predict the SCD endpoints after adjustment for the clinical risk predictors and late gadolinium enhancement. Furthermore, the univariately significant risk predictor was improved by the addition of the selected radiomics features, LBP (19) and Moment (1), to predict SCD events (P &lt; 0.05).Conclusion: The radiomics features of LBP (19) and Moment (1) extracted from LGE images, reflecting scar heterogeneity, have independent prognostic value in identifying high SCD risk patients with HCM.
Adverse Outcome in COVID-19 Is Associated With an Aggravating Hypo-Responsive Platelet Phenotype
Authors: Schrottmaier Waltraud C. , Pirabe Anita , Pereyra David , Heber Stefan , Hackl Hubert , Schmuckenschlager Anna , Brunnthaler Laura , Santol Jonas , Kammerer Kerstin , Oosterlee Justin , Pawelka Erich , Treiber Sonja M. , Khan Abdullah O. , Pugh Matthew , Traugott Marianna T. , Schörgenhofer Christian , Seitz Tamara , Karolyi Mario , Jilma Bernd , Rayes Julie , Zoufaly Alexander , Assinger Alice 
Published: December 2021

Thromboembolic complications are frequently observed in Coronavirus disease 2019 (COVID-19). While COVID-19 is linked to platelet dysregulation, the association between disease outcome and platelet function is less clear. We prospectively monitored platelet activation and reactivity in 97 patients during the first week of hospitalization and determined plasma markers of platelet degranulation and inflammation. Adverse outcome in COVID-19 was associated with increased basal platelet activation and diminished platelet responses, which aggravated over time. Especially GPIIb/IIIa responses were abrogated, pointing toward impeded platelet aggregation. Moreover, platelet-leukocyte aggregate formation was diminished, pointing toward abrogated platelet-mediated immune responses in COVID-19. No general increase in plasma levels of platelet-derived granule components could be detected, arguing against platelet exhaustion. However, studies on platelets from healthy donors showed that plasma components in COVID-19 patients with unfavorable outcome were at least partly responsible for diminished platelet responses.Taken together this study shows that unfavorable outcome in COVID-19 is associated with a hypo-responsive platelet phenotype that aggravates with disease progression and may impact platelet-mediated immunoregulation.
Remediation Potential of Borehole Thermal Energy Storage for Chlorinated Hydrocarbon Plumes: Numerical Modeling in a Variably-Saturated Aquifer
Authors: Meng Boyan , Yang Yan , Huang Yonghui , Kolditz Olaf , Shao Haibing 
Published: December 2021

Underground thermal energy storage is an efficient technique to boost the share of renewable energies. However, despite being well-established, their environmental impacts such as the interaction with hydrocarbon contaminants is not intensively investigated. This study uses OpenGeoSys software to simulate the heat and mass transport of a borehole thermal energy storage (BTES) system in a shallow unconfined aquifer. A high-temperature (70 C) heat storage scenario was considered which imposes long-term thermal impact on the subsurface. Moreover, the effect of temperature-dependent flow and mass transport in a two-phase system is examined for the contaminant trichloroethylene (TCE). In particular, as subsurface temperatures are raised due to BTES operation, volatilization will increase and redistribute the TCE in liquid and gas phases. These changes are inspected for different scenarios in a contaminant transport context. The results demonstrated the promising potential of BTES in facilitating the natural attenuation of hydrocarbon contaminants, particularly when buoyant flow is induced to accelerate TCE volatilization. For instance, over 70% of TCE mass was removed from a discontinuous contaminant plume after 5 years operation of a small BTES installation. The findings of this study are insightful for an increased application of subsurface heat storage facilities, especially in contaminated urban areas.
Quantifying Temperature and Precipitation Change Caused by Land Cover Change: A Case Study of India Using the WRF Model
Authors: Lal Preet , Shekhar Ankit , Kumar Amit 
Published: December 2021

The large-scale Land-Uses and Land-Cover Changes (LULCC) in India in the past several decades is primarily driven by anthropogenic factors that influence the climate from regional to global scales. Therefore, to understand the LULCC over the Indian region from 2002 to 2015 and its implications on temperature and precipitation, we performed Weather Research Forecast (WRF) model simulation using the European Centre for Medium-Range Weather Forecast (ECMWF) reanalysis data for the period 2009 to 2015 as a boundary condition with 2009 as spin-up time. The results showed moderate forest cover loss in major parts of northeast India, and the Himalayan region during 2002–2015. Such large LULC changes, primarily significant alteration of grassland and agriculture from the forest, led to increased precipitation due to increasing evapotranspiration (ET) similar to the forest-dominated regions. An increase in the precipitation patterns (&gt;300 mm) was observed in the parts of eastern and western Himalayas, western Ghats, and the northwestern part of central India, while most parts of northeast Himalayas have an exceptional increase in precipitation (∼100–150 mm), which shows similar agreement with an increase of leaf area index (LAI) by ∼15%. The overall phenomenon leads to a greening-induced ET enhancement that increases atmospheric water vapor content and promotes downwind precipitation. In the case of temperature, warming was observed in the central to eastern parts of India, while cooling was observed in the central and western parts. The increase in vegetated areas over northwest India led to an increase in ET, which ultimately resulted in decreased temperature and increased precipitation. The study highlights the changes in temperature and precipitation in recent decades because of large LULCC and necessitates the formulation of sustainable land use-based strategies to control meteorological variability and augment ecological sustainability.