bluuebunny/crossref_metadata_2025_split huggingface dataset:
Composition of organics on asteroid (101955) Bennu
Authors: Kaplan H. H. , Simon A. A. , Hamilton V. E. , Thompson M. S. , Sandford S. A. , Barucci M. A. , Cloutis E. A. , Brucato J. , Reuter D. C. , Glavin D. P. , Clark B. E. , Dworkin J. P. , Campins H. , Emery J. P. , Fornasier S. , Zou X. D. , Lauretta D. S. 
Published: August 2021

Context. The Origins, Spectral Interpretation, Resource Identification, and Security-Regolith Explorer (OSIRIS-REx) mission detected an infrared absorption at 3.4 μm on near-Earth asteroid (101955) Bennu. This absorption is indicative of carbon species, including organics, on the surface.
Aims. We aim to describe the composition of the organic matter on Bennu by investigating the spectral features in detail.
Methods. We use a curated set of spectra acquired by the OSIRIS-REx Visible and InfraRed Spectrometer that have features near 3.4 μm (3.2 to 3.6 μm) attributed to organics. We assess the shapes and strengths of these absorptions in the context of laboratory spectra of extraterrestrial organics and analogs.
Results. We find spectral evidence of aromatic and aliphatic CH bonds. The absorptions are broadly consistent in shape and depth with those associated with insoluble organic matter in meteorites. Given the thermal and space weathering environments on Bennu, it is likely that the organics have not been exposed for long enough to substantially decrease the H/C and destroy all aliphatic molecules.
Evidence of the multi-thermal nature of spicular downflows
Authors: Bose Souvik , Rouppevan der Voort Luc , Joshi Jayant , Henriques Vasco M. J. , Nóbrega-Siverio Daniel , Martínez-Sykora Juan , De Pontieu Bart 
Published: August 2021

Context. Spectroscopic observations of the emission lines formed in the solar transition region commonly show persistent downflows on the order of 10−15 km s−1. The cause of such downflows, however, is still not fully clear and has remained a matter of debate.
Aims. We aim to understand the cause of such downflows by studying the coronal and transition region responses to the recently reported chromospheric downflowing rapid redshifted excursions (RREs) and their impact on the heating of the solar atmosphere.
Methods. We have used two sets of coordinated data from the Swedish 1 m Solar Telescope, the Interface Region Imaging Spectrograph, and the Solar Dynamics Observatory for analyzing the response of the downflowing RREs in the transition region and corona. To provide theoretical support, we use an already existing 2.5D magnetohydrodynamic simulation of spicules performed with the Bifrost code.
Results. We find ample occurrences of downflowing RREs and show several examples of their spatio-temporal evolution, sampling multiple wavelength channels ranging from the cooler chromospheric to the hotter coronal channels. These downflowing features are thought to be likely associated with the returning components of the previously heated spicular plasma. Furthermore, the transition region Doppler shifts associated with them are close to the average redshifts observed in this region, which further implies that these flows could (partly) be responsible for the persistent downflows observed in the transition region. We also propose two mechanisms – (i) a typical upflow followed by a downflow and (ii) downflows along a loop –from the perspective of a numerical simulation that could explain the ubiquitous occurrence of such downflows. A detailed comparison between the synthetic and observed spectral characteristics reveals a distinctive match and further suggests an impact on the heating of the solar atmosphere.
Conclusions. We present evidence that suggests that at least some of the downflowing RREs are the chromospheric counterparts of the transition region and lower coronal downflows.
Monitoring the number of trips on open-ground tomatoes
Authors: Tyutyuma Natalya , Bondarenko Anastasia 
Published: August 2021

The agroclimatic resources of the Astrakhan region are quite large and represent huge opportunities in the production of heat-loving crops such as vegetables and melons. The region has accumulated a great scientific and production experience in the cultivation of tomatoes as the main vegetable crop rotation crop.To date, the first task for farmers of the region is to develop new modern agrotechnological techniques to eliminate the spread of thrips on open-ground tomato plants. The object of research was a hybrid of tomato of the domestic selection of the agricultural company Sedek Azhur F1. Materials and methods.For the first time, for the conditions of light chestnut soils on the land use territory of FSBNU “Caspian Agrarian Scientific Federal Scientific Center of the Russian Academy of Sciences” during 20182020. the influence of various insecticides in the fight against tripasmi was studied.As a result of the analysis, the presented scientific article presents the main results for the study of new modern insecticides in the fight against trypses on open-ground tomato Azhur F1. According to the results of three years of study, the optimal option with the use of the drug Confidor Extra was revealed, which contributes to a significant decrease in the number of phytophages.The use of these preparations had no phytotoxic effect on open-ground tomato plants. In the version using the insecticide Confidor Extra, there was more purely commercial fruits and a significant increase in the crop relative to control without treatments, as well as a variant where the Fufanon-Nova preparation was used. The increase relative to control in the high-yield version was + 40.8 t/ha or 43.5%.
Problems of regional management of innovative food industry development
Authors: Kilimova Ludmila , Nishnianidze Olga , Cherkashin Michael , Pykhtin Alexey 
Published: August 2021

The article describes the need to consider management of innovative food industry development at all levels of national economy. Management of innovative potential of regional economic entities is considered as a set of processes and activities of management cycle, forms, and methods of its organization, aimed at ensuring innovative development of economic entities, achieving formulated mission and innovative goals using a focused impact on innovative potential components.Organizational structure of state management of innovative potential is also described. Horizontalvertical structure of innovative potential management of regional economic entities of Russian food industry is based on this structure. It is described in the context of all levels of national economy. Innovative potential of regional economic entities is managed according to the principle of complexity, systemicity, goal commitment and continuality. A resource-based approach has been identified for innovation capacity management process.
Iodine deficiency: socio-economic problems and new approaches to its solution in veterinary medicine
Authors: Yevglevsky Alexey , Gostev Andrey 
Published: August 2021

One of the global, vital problems of humanity is iodine deficiency. According to the World Health Organization (WHO), more than 2 billion people live in conditions of iodine deficiency. people: among them, 740 million have endemic goiter, 43 million have mental retardation, more than 6 million. they suffer from cretinism (an extreme degree of mental retardation). Currently, iodine deficiency diseases are the most common non-infectious diseases in the world.What about mammalian animals? In animals, iodine performs the same functions as in humans. Animals, especially agricultural animals, are just as sensitive to iodine deficiency as humans. With a lack of iodine in the body of animals, the biosynthesis of thyroid hormones is disrupted, which leads to a decrease in the intensity of redox processes, as a result of which all types of metabolism are disrupted:-protein, fat, carbohydrate, macro – and microelement, energy. In this regard, the failure of the thyroid gland is accompanied by the development of severe pathobiochemical processes, which, in the end, leads to the clinical manifestation of pathophysiological conditions. Taking into account the fact that in conditions of constant iodine deficiency it is very problematic to ensure the health of productive animals, the issues of prevention of iodine deficiency conditions are economically significant for industrial animal husbandry. It is no accident that in countries experiencing natural iodine deficiency, state programs have been developed that provide for the use of iodine-containing additives in the diets of productive animals. Despite the fact that the simplest and most affordable method of eliminating iodine deficiency in humans and animals is the inclusion of iodized salt in the diet, however, this method can not be used for veterinary purposes. First of all, the feed method of using biologically active additives eliminates the possibility of dosed therapeutic or preventive treatment. On the pages of this article, we draw attention to the emerging prospects for the use of a new iodine-metabolic composition in non-infectious and infectious pathology, based on an iodine polymer complex known in pharmacology as iodinol and succinic acid.
Clinical symptoms of iodine and zinc deficiency in dairy cows
Authors: Nikulin Ivan , Kalyuzhny Ivan 
Published: August 2021

Numerous clinical observations indicate that the silage-concentrate type of dairy cows feeding causes a cascade of pathobiochemical processes occurring by the type of metabolic acidosis, ketosis, hepatosis, with a violation of protein, fat and carbohydrate metabolism. Animals cannot realize the genetically inherent productivity potential.The culling of cows from the main herd is more than 37%. The main reasons for culling cows are hypo - and agalactia as a result of mastitis and ketosis, as well as infertility against the background of repeated infertile inseminations. Allotriophagy, unsteadiness of teeth, resorption of the last tail vertebrae, curvature of the vertebral column, traces of rib fractures, difficulty in lifting and moving when the content of total calcium and inorganic phosphorus in the blood is at the lower limit of physiological values indicate osteodystrophy. Exo-or endophthalmos, myxedema, forelock and mane, disheveled and curly hair, abortions, the birth of premature, ugly, stillborn, sparsely haired or “naked” calves against the background of low levels of protein bound iodine (PBI) in the blood indicate iodine deficiency in their body (hypomicroelementosis J). Coarsening and increased folding of the skin in the area of the head, neck and withers, active keratization on the skin in the area of articular surfaces and croup, thickening of the corolla zone and the border of the hooves in the form of a roller, ski-like growth and deformation of the hoof horn, enlargement and deformation of the joints, decreased reproductive function and low levels of zinc in the blood indicate parakeratosis of cattle (zinc deficiency).
Modern concept of probiotics and principles of development of new-generation symbiotic preparations
Authors: Gayane Svazlyan , Viktor Popov , Nikolay Naumov 
Published: August 2021

The purpose of this work is to review data on the biological effectiveness of probiotics, their mechanisms of action, and the prospects for the development of new-generation preparations. Scientific and practical justification of symbiotic drugs of a new generation – metabiotics as a continuation of the probiotic concept is given. The authors discuss the literature data and their own results, which allow them to propose new approaches to the creation of symbiotic drugs. The authors scientifically substantiate the main scientific provisions of the probiotic concept for the development of new-generation symbiotic drugs:study of aspects of the cultivation of the metabolic probioticB. bifidumstrain No. 1 in appropriate nutrient media;determination of the quantitative and qualitative composition of metabolites in the probiotic producer;scientific and practical substantiation of the qualitative and quantitative composition of the experimental probiotic suspension as a biologically active additive;the effect of probiotic suspension on the metabolism, the formation of microbiocenosis and nonspecific immunity. The substantiation for the creation of new feed probiotic preparations in the form of a composition of living microorganisms with molasses-based metabolites is given, which has a certain scientific and practical significance, and is promising for use in animal diets. Studies have found that to stabilize normal microflora in suckling pigs and weanlings, it is advisable to use various drugs in the form of biologically active additives of probiotic agents and their metabolites. The article provides a scientific and practical justification of a dietary supplement for correcting the microbiocenosis of the gastrointestinal tract and some factors of cellular immunity in growing young pigs based on the probiotic microorganismB. bifidumwhen cultivated on a nutrient medium from molasses.
Pharmacological correction of technological stress in bulls and assessment of the influence of stress factors on semen quality
Authors: Chaplynskikh Anastasiia , Nikulin Ivan 
Published: August 2021

The current conditions for the intensification of animal husbandry dictate a significant increase in the physiological and functional load on the body of productive animals, resulting in a failure of adaptive capacity, which manifest themselves in the violation of reproduction function and the development of pathological states. Research by domestic and foreign scientists has shown that stress plays a leading role in the etiology and pathogenesis of diseases leading to a reduction in animal reproduction [3, 4, 9]. Although the topic of stress is often covered in the scientific literature, some of its features are not fully explored. This is particularly true for male producers whose genetic material has a direct impact on livestock productivity and livestock production [1, 3, 4, 11]. Therefore, the study of the influence of stress factors on the reproductive capacity of males and their pharmaco-rectification is relevant. The aim of our research was to assess the degree of influence of technological stress factors on the reproduction function of the bull producers and to develop a pharmaco-correction scheme to prevent stress effects on sperm quality. In relation to the objective, the following objectives were proposed:1. Study the reaction of the ox producers to the effects of technological stress;2. Determine the influence of drugs Amber biostimulator, Azoxyvet on the quality of bull sperm.
Arzneipflanzen zur Prophylaxe und Therapie der Hufrehe
Authors: Brendieck-Worm Cäcilia 
Published: August 2021

ZusammenfassungSekundärstoffreiches Futter (Weide, Heu) und der gezielte Einsatz von Arzneipflanzen zur Unterstützung von Stoffwechsel, Entgiftung, Blutfließeigenschaften, Durchblutung und Gefäßgesundheit bieten Schutz vor Hufrehe. Bei akuter Rehe empfehlen sich pflanzliche Adaptogene und Sedativa sowie antiphlogistisch und analgetisch wirksame Arzneipflanzen.
Development and Validation of a Species-specific PCR Method for the Identification of Ginseng Species Using Orthogonal Approaches
Authors: Lu Zhengfei , Handy Sara M. , Zhang Ning , Quan Zheng , Xu Qun , Ambrose Michael , Giancaspro Gabriel , Sarma Nandakumara D. 
Published: August 2021

AbstractWhen testing botanical ingredients of herbal medicines and dietary supplements, the complexity of botanical matrixes often requires the use of orthogonal methods to establish identification procedures suitable for quality control purposes. Genomic-based botanical identification methods are evolving and emerging as useful quality control tools to complement traditional morphological and chemical identification methods. Species-specific polymerase chain reaction methods are being evaluated for botanical quality control and as a cost-effective approach to identify and discriminate between closely related botanical species. This paper describes orthogonal identification of Panax ginseng, P. quinquefolius, and P. notoginseng materials in commerce as an example of the development and validation of a set of species-specific polymerase chain reaction methods to establish botanical identity in ginseng roots. This work also explored the possibility of extending the
application of species-specific polymerase chain reaction methods to provide species identity information for processed materials, such as steamed roots and hydroalcoholic extracts, and showed success with this approach. Finally, the paper provides recommendations for an out-of-specification investigation of samples that may pass some of the orthogonal tests and fail others.
Assessment of a Novel, 22-lead Mobile Electrocardiogram in Elite, Adolescent Footballers
Authors: Johnson Harvey , Duarte Nuno , Ryding Diane , Perry Dave , McNally Steve , Stuart A. Graham , Williams Craig Anthony , Pieles Guido 
Published: August 2021

AbstractThe 12-lead electrocardiogram is a key component of cardiac screening in elite adolescent footballers. Current technology hampers mobile electrocardiogram monitoring that could reduce the time-to-diagnosis in symptomatic athletes. Recently, a 22-lead mobile electrocardiogram monitor, CardioSecur (Personal MedSystems GmbH), has been approved for use in adults. In this study, the differences in parameter accuracy between CardioSecur’s 22-lead electrocardiogram and the gold standard 12-lead electrocardiogram were assessed in elite adolescent footballers (n=31) using Bland-Altman and paired t-tests/Wilcoxon analysis. Agreement between the two devices was clinically acceptable for heart rate (bias=− 0.633 bpm), PR Interval (bias=− 1.73 ms), Bazzett’s corrected QTc interval (bias=2.03 ms), T-wave axis (bias=6.55°), P-wave duration (bias=− 0.941 ms), Q-wave amplitude (bias=0.0195 mV), Q-wave duration (bias=1.98 ms), rhythm (bias=0.0333), ST-segment (bias=− 0.0629), J-point analysis (bias=− 0.01) and extended T wave and QRS duration analysis. Unsatisfactory agreement was observed in QRS axis (bias=− 19.4°), P-wave axis (bias=− 0.670°), QRS amplitude (bias=− 0.660 mV), P-wave amplitude (bias=0.0400 mV) and T-wave amplitude (bias=− 0.0675 mV). CardioSecur’s 22-lead electrocardiogram agrees with the gold standard in rhythm, durations, T-wave determination in all leads assessed, permitting its use in adolescent footballers for immediate pitch- or track-side analysis.
Prenylated Acylphloroglucinols from Hypericum jovis with Anti-inflammatory Potential
Authors: Grafakou Maria-Eleni , Barda Christina , Pintać Diandra , Lesjak Marija , Heilmann Jörg , Skaltsa Helen 
Published: August 2021

AbstractThirteen prenylated acylphloroglucinols (1–13), including 2 previously undescribed compounds (1) and (2), were isolated from Hypericum jovis. Their structures were elucidated by high-field NMR spectroscopy. The isolated prenylated acylphloroglucinols were evaluated for their anti-inflammatory effects in vitro through the reduction of the intercellular adhesion molecule 1 expression induced by TNF-α in the human microvascular endothelial cells 1 cell line. Compounds 3, 5, 6, 8, and 12 significantly reduced intercellular adhesion molecule 1 expression in a concentration-dependent manner with IC50 values of 16.9, 34.4, 4.0, 3.2, and 7.7 µM, respectively. In addition, compound 12 showed notable inhibitory activity on the formation of cyclooxygenase-1- and 12-lipoxygenase-derived inflammatory mediators in an ex vivo cyclooxygenase-lipoxygenase assay. Eleven further constituents were
isolated (14–24), including the rare quercetin 3-O-(2-O-acetyl)-arabinofuranoside (18).
Avaliações do lúmen da artéria reparada em lesões do antebraço usando o teste de Allen, Doppler portátil e ultrassonografia com Doppler
Authors: Cagnolati Amanda Favaro , Andrade Fernanda Ruiz , Serrano Sara Dadona Correia , Barbieri Claudio Henrique , Mazzer Nilton , Nogueira-Barbosa Marcello Henrique 
Published: August 2021

Resumo
Objetivo O objetivo deste estudo foi avaliar a taxa de perviedade pós-operatória de lesões arteriais do antebraço secundárias a traumatismo penetrante. As lesões foram submetidas a reparo primário e examinadas com o teste de Allen e um dispositivo Doppler portátil; posteriormente, os resultados foram confirmados à ultrassonografia com Doppler.
Métodos Dezoito pacientes foram incluídos, com um total de 19 lesões arteriais, 14 lesões ulnares e 5 lesões radiais; um paciente tinha lesões em ambos os antebraços. Todos os pacientes foram submetidos à cirurgia e três avaliações clínicas: o teste de Allen e a avaliação do fluxo sanguíneo arterial com um dispositivo portátil de Doppler na 4ª e 16ª semanas após a cirurgia e ultrassonografia com Doppler 12 semanas após o procedimento.
Resultados Na primeira avaliação clínica, 77% dos pacientes apresentavam perviedade segundo o teste de Allen e 72% apresentavam som pulsátil identificado pelo Doppler portátil. Na segunda avaliação, 61% dos pacientes apresentaram perviedade com base no teste de Allen e a taxa de som pulsátil ao Doppler portátil foi de 72%, semelhante à observada 2 meses antes. À ultrassonografia com Doppler (cerca de 12 semanas após a cirurgia), a taxa de sucesso da arteriorrafia foi de 88%. Em relação à perviedade final (avaliação por ultrassonografia com Doppler) e mecanismo de trauma, todos os pacientes com traumatismo penetrante apresentavam artérias pérvias.
Conclusão Concluímos que a avaliação clínica com um dispositivo Doppler portátil e o teste de Allen é confiável caso a artéria pérvia possa ser palpada. No entanto, a ultrassonografia pode ser necessária em caso de impossibilidade de localização de uma artéria pérvia durante o exame clínico.
Lingual Flap Protection during Third Molar Surgery: A Literature Review
Authors: Petroni Giulia , Passaretti Alfredo , Zaccheo Fabrizio , Di Nardo Dario , Testarelli Luca , Cicconetti Andrea 
Published: August 2021

AbstractThe purpose of this review was to analyze how the retraction and protection of lingual flap (LF+) could influence the incidence of lingual nerve injury (LNI) during third molar extraction, as compared with protocols that do not involve handling of lingual tissue (LF). A literature review was performed from the “Medline” and “Scopus” medical databases, using the keywords “lingual nerve” and “third molar surgery.” From the selected articles, the mean values for transitory and permanent LNI’s incidence were elaborated, taking into account the group treated with LF+ technique and the group treated with LF technique. Of 480 articles, 11 studies were included in the review. The LF+ group counted 3,866 surgeries and it resulted in a transitory LNI’s mean incidence of 2.98 ± 0.03% and a mean incidence of 0.1 ± 0.003% for permanent LNI. The LF group counted 5,938 surgeries with, respectively, 1.92 ± 0.02 and 0.49 ± 0.006% of transitory and permanent LNI’s incidence mean values. The results of this study suggest that the application of LF+ techniques reduces the risk of damage and injuries of lingual nerve.