bluuebunny/crossref_metadata_2025_split huggingface dataset:
A deep transfer learning framework for the automated assessment of corneal inflammation on in vivo confocal microscopy images
Authors: Xu Fan , Qin Yikun , He Wenjing , Huang Guangyi , Lv Jian , Xie Xinxin , Diao Chunli , Tang Fen , Jiang Li , Lan Rushi , Cheng Xiaohui , Xiao Xiaolin , Zeng Siming , Chen Qi , Cui Ling , Li Min , Tang Ningning 
Published: June 2021

PurposeInfiltration of activated dendritic cells and inflammatory cells in cornea represents an important marker for defining corneal inflammation. Deep transfer learning has presented a promising potential and is gaining more importance in computer assisted diagnosis. This study aimed to develop deep transfer learning models for automatic detection of activated dendritic cells and inflammatory cells using in vivo confocal microscopy images.MethodsA total of 3453 images was used to train the models. External validation was performed on an independent test set of 558 images. A ground-truth label was assigned to each image by a panel of cornea specialists. We constructed a deep transfer learning network that consisted of a pre-trained network and an adaptation layer. In this work, five pre-trained networks were considered, namely VGG-16, ResNet-101, Inception V3, Xception, and Inception-ResNet V2. The performance of each transfer network was evaluated by calculating the area under the curve (AUC) of receiver operating characteristic, accuracy, sensitivity, specificity, and G mean.ResultsThe best performance was achieved by Inception-ResNet V2 transfer model. In the validation set, the best transfer system achieved an AUC of 0.9646 (P<0.001) in identifying activated dendritic cells (accuracy, 0.9319; sensitivity, 0.8171; specificity, 0.9517; and G mean, 0.8872), and 0.9901 (P<0.001) in identifying inflammatory cells (accuracy, 0.9767; sensitivity, 0.9174; specificity, 0.9931; and G mean, 0.9545).ConclusionsThe deep transfer learning models provide a completely automated analysis of corneal inflammatory cellular components with high accuracy. The implementation of such models would greatly benefit the management of corneal diseases and reduce workloads for ophthalmologists.
Endogenous erythropoietin concentrations and association with retinopathy of prematurity and brain injury in preterm infants
Authors: Fahim Nancy M. , Georgieff Michael K. , Zhang Lei , Naisbitt Scott , Rao Raghavendra B. , Inder Terrie E. 
Published: June 2021

BackgroundEndogenous erythropoietin (EPO) concentrations vary widely in preterm infants and may be associated with perinatal risk factors and neurological outcomes. Erythropoietin is elevated in fetal hypoxia but is also a potential neuroprotectant.MethodsIn a prospective study of 27 infants ≤ 30 weeks gestation, serum erythropoietin concentrations were measured during the first month of life, on day 1 and weeks 1, 2, and 4, and related to perinatal risk factors and outcomes including retinopathy of prematurity and cerebral injury evaluated near term-equivalent post menstrual age using magnetic resonance imaging with quantitative scoring.ResultsLower birth weight was associated with higher EPO concentrations throughout the first 2 weeks of life (r = -0.6, p < 0.01). Higher day 1 and week 1 EPO concentrations were associated with lower Apgar score at 1 minute (r = - 0.5) and 5 minutes (r = -0.7), respectively (p < 0.01). Higher day 1 EPO concentrations and 2-week area under the curve were associated with increased risk (p = 0.01) and severity (r = 0.5, p < 0.02) of retinopathy of prematurity. Higher EPO concentrations at 2 weeks were associated with increased total brain injury score (r = 0.5, p < 0.05).ConclusionElevated endogenous erythropoietin concentrations in the first two weeks of life are associated with lower birth weight and increased risk of adverse outcomes.
Predictive utility of fibrinogen in acute kidney injury in living donor liver transplantation: A propensity score-matching analysis
Authors: Park Jaesik , Joo Min A. , Choi Ho Joong , Hong Sang Hyun , Park Chul Soo , Choi Jong Ho , Chae Min Suk 
Published: June 2021

BackgroundThis study investigated the association between the fibrinogen level and the risk of acute kidney injury (AKI) in patients who have undergone living donor liver transplantation (LDLT).Patients and methodsA total of 676 patients who underwent LDLT were analyzed retrospectively. Exclusion criteria included a history of severe kidney dysfunction, emergency operation, deceased donor, ABO-incompatible transplantation, and missing data. The study population was divided into low and normal fibrinogen groups. A 1:1 propensity score (PS) matching analysis was used to evaluate the association between a low fibrinogen level (< 160 mg/dL) and postoperative development of AKI.ResultsIn total, 142 patients (23.1%) developed AKI after LDLT. The PS matching analysis showed that the probability of AKI was two-fold higher in the low fibrinogen group than in the normal fibrinogen group. In addition, patients with AKI had poorer postoperative outcomes such as longer hospitalization, longer ICU stay, and higher mortality than patients without AKI.ConclusionsThe preoperative fibrinogen level may be useful for risk stratification of patients undergoing LDLT in terms postoperative development of AKI.
Analyzing the profile of the manager from the perspective of the employees: A case study
Authors: Albuquerque André , Melo Fagner José Coutinho de , Xavier Larissa , Medeiros Denise Dumke 
Published: June 2021

Goal: This paper proposes to study the leader's profile using the Johari Window to establish feedback on the leader's behavior in comparison with the employees' point of view.
Design / Methodology / Approach: The case study was carried out in a given material distribution center for civil construction through a questionnaire, based on the Johari window model. The research was classified as applied, exploratory, qualitative and case study.
Results: Most of the respondents in the surveyed sector have the opinion that their leader is inserted in the “blind” area of Johari window, that is, it is an area unknown to the leader, either because subordinates do not want to share feedback or because the leader is not able or does not care about it. Through these results, improvements were proposed.
Limitations of the investigation: The questionnaire was only applied in one moment, and it is not possible to compare the leader's Johari window with the posterior view of each team member.
Practical implications: When leaders share their way of thinking and acting and are willing to receive feedback, there will be greater clarity in communication and executing objectives. With this, it is possible to obtain more qualified and motivated personnel for the performance of the organization's activities, reducing costs, increasing productivity, generating a competitive advantage.
Originality / Value: Understanding the relationship between the leader and followers in the researched sector, verifying the confrontation of the opinion of the followers about the behavior of the leader in order to improve the organizational environment to achieve the objectives.
Place Attachment Masyarakat di RW 04, Kelurahan Polehan, Kota Malang
Authors: Haryani Efma , Rukmi Wara Indira , Setyono Deni Agus 
Published: June 2021

The settlement area in RW 04 is determined as one of the priority areas that the Government of Malang City should overcome from slum problems. Slum factors in RW 04 are caused by density settlement, unlivable residential area, and environmental pollution by the community activities. Therefore, the local government creates a program to diminish the slum and to support the 100-0-100 Program as well. The effort to overcome the slum problems is done through a progam called PLPBK (Penataan Lingkungan Permukiman Berbasis Komunitas) which can affect community place attachment. Hence, the community image of RW 04 would change from a slum into a clean and beautiful residential area. The environmental transformation in RW 04 could strengthen place attachment and as a result, the people feel more comfortable, proud, and safe. This study aims to identify community place attachment in RW 04, Polehan, Malang and the analysis used is descriptive statistics. This research shows that the community would have a strong place attachment as long as the respondents have the willingness to develop place attachment through experience, intensity of social interaction, the possession of valuable object, action or effort to control the environment, the length of resident, do not migrate, and RW 04 that is able to replace the childhood memories of immigrant. The strong place attachment is affected by the respondents characteristics as well, and as a result, they tend to have willingness to live in RW 04.
Effect of different dosage of EMS on germination, survivability and morpho-physiological characteristics of sunflower seedling
Authors: Habib Sheikh Hasna , Akanda Md. Abdul Latif , Roy Pryanka , Kausar Hossain 
Published: June 2021

Abstract
To find out the effect of EMS dosage on sunflower variety BARI Surjamukhi-2, different EMS concentrations were compared at the molecular biology laboratory (MBL), Oilseed Research Centre (ORC), Bangladesh Agricultural Research Institute (BARI), Gazipur. A total of 10 seeds were treated with each treatment and % germination, % survival and early seedling growth was investigated. Decreased % germination was found with the increasing dose of EMS for all the treatment compared to the control, except for T
4 (0.6% EMS) treatment where a 100% seed was found to be germinated. With an exception of treatment T
4, a decreasing trend of % survivability with the increasing dose of EMS was observed. The gradual reduction with the increasing dose of EMS were observed for most of the studied characters such as leaf area, number of internodes, internode length, fresh and dry weight of leaf, dry weight of shoot, and fresh and dry weight of root in comparison to non-treated control seedlings. However, stimulatory effect with lower dosage of EMS was observed for shoot length in T
2 (0.2% EMS), root length in T
3 (0.4% EMS), and stem fresh weight in T
2 over control. Based on a quadratic regression analysis, using % survivability data, LD50 was calculated and optimum EMS dose was found 0.5%. Hence, the optimized EMS dose of 0.5% may be used to develop large scale desirable mutant of sunflower variety BARI Surjamukhi-2.
The experimental study of CFRP interlayer of dissimilar joint AA7075-T651/Ti-6Al-4V alloys by friction stir spot welding on mechanical and microstructural properties
Authors: Nasir Tauqir , Kalaf Omer , Asmael Mohammed , Zeeshan Qasim , Safaei Babak , Hussain Ghulam , Motallebzadeh Amir 
Published: June 2021

AbstractThe present study focused on two dissimilar metal alloys: AA7075-T651 and Ti-6Al-4V alloys with additional carbon fiber-reinforced polymer (CFRP) as an interlayer were welded together by friction stir spot welding (FSSW). The effect of welding parameters (rotational speed and dwell time) and carbon fiber-reinforced polymer on mechanical and microstructural properties of a weld joint was investigated. The obtained results explore the parametric effects on mechanical properties of the weld joint. The maximum tensile shear load 2597.8 N was achieved at the rotational speed of 2,000 rpm and dwell time of 10 s. While at the same rotational speed, 54.7% reduction in the tensile shear load was attained at shorter dwell time of 5 s. Therefore, dwell time plays an important role in the tensile shear load of a weld joint. The scanning electron microscope (SEM-EDS) results show the formation of intermetallic compound of Ti3Al and Ti-Al-C that significantly affect the mechanical and microstructural properties of the weld joint. Moreover, the effect of the rotational speed on micro-hardness was found at significant than dwell time. The micro-hardness of the weld joint increase by 18.90% in the keyhole rather than the stir zone and the thermomechanical affected zone, which might be due to the presence of ternary (Ti-Al-C) intermetallic compound.
Entwicklung von zertifizierten Referenzproben für den thermoelektrischen Leistungsfaktor
Authors: Haupt Sebastian , Huang Kai , Edler Frank , Ziolkowski Pawel 
Published: June 2021

Zusammenfassung
Thermoelektrische Generatoren (TEGs) ermöglichen es, ungenutzte Wärme mithilfe des Seebeck-Effektes in elektrische Energie zu überführen. Die Entwicklung von effizienten thermoelektrischen Materialien und TEGs wird durch den Mangel an geeigneten Referenzmaterialien und einer rückführbaren Messtechnik erschwert. An der Physikalisch-Technische Bundesanstalt (PTB) wird seit einigen Jahren an der Entwicklung von thermoelektrischen Referenzmaterialien und der zugehörigen Messtechnik geforscht [1]. Im Rahmen des Projektes „TEST-HT“ (Thermoelektrische Standardisation für hohe Temperaturen), wird das weltweit erste halbleitende Referenzmaterial für den Leistungsfaktor im Bereich von 300 K bis 1000 K entwickelt. Als Material wurde Kobalt dotiertes β-Eisendisilizid (β-Fe0.95Co0.05Si2) (FeSi2) ausgewählt, welches von unserem Projektpartner, dem Deutschen Zentrum für Luft- und Raumfahrt (DLR), hergestellt wird [2]. In diesem Artikel beschreiben wir den aktuellen Stand der Zertifizierung des FeSi2.
Effects of Withdrawal from Cocaine Self-Administration on Rat Orbitofrontal Cortex Parvalbumin Neurons ExpressingCre recombinase: Sex-Dependent Changes in Neuronal Function and Unaltered Serotonin Signaling
Authors: Wright Andrew M. , Zapata Agustin , Hoffman Alexander F. , Necarsulmer Julie C. , Coke Lamarque M. , Svarcbahs Reinis , Richie Christopher T. , Pickel James , Hope Bruce T. , Harvey Brandon K. , Lupica Carl R. 
Published: June 2021

AbstractThe orbitofrontal cortex (OFC) is a brain region involved in higher-order decision-making. Rodent studies show that cocaine self-administration (CSA) reduces OFC contribution to goal-directed behavior and behavioral strategies to avoid drug intake. This change in OFC function persists for many weeks after cocaine withdrawal, suggesting involvement in the process of addiction. The mechanisms underlying impaired OFC function by cocaine are not well-understood. However, studies implicate altered OFC serotonin (5-HT) function in disrupted cognitive processes during addiction and other psychiatric disorders. Thus, it is hypothesized that cocaine impairment of OFC function involves changes in 5-HT signaling, and previous work shows that 5-HT1Aand 5-HT2Areceptor-mediated effects on OFC pyramidal neurons (PyNs) are impaired weeks after cocaine withdrawal. However, 5-HT effects on other contributors to OFC circuit function have not been fully investigated, including the parvalbumin-containing, fast-spiking interneurons (OFCPV), whose function is essential to normal OFC-mediated behavior. Here, 5-HT function in naive rats and those withdrawn from CSA were evaluated using a novel rat transgenic line in which the rat parvalbumin promoter drives Cre-recombinase expression to permit identification of OFCPVcells by fluorescent reporter protein expression. We find that whereas CSA altered basal synaptic and membrane properties of the OFCPVneurons in a sex-dependent manner, the effects of 5-HT on these cells were unchanged by CSA. These data suggest that the behavioral effects of dysregulated OFC 5-HT function caused by cocaine experience are primarily mediated by changes in 5-HT signaling at PyNs, and not at OFCPVneurons.
Acoustically Driven Cortical δ Oscillations Underpin Prosodic Chunking
Authors: Rimmele J. M. , Poeppel D. , Ghitza O. 
Published: June 2021

AbstractOscillation-based models of speech perception postulate a cortical computational principle by which decoding is performed within a window structure derived by a segmentation process. Segmentation of syllable-size chunks is realized by a θ oscillator. We provide evidence for an analogous role of a δ oscillator in the segmentation of phrase-sized chunks. We recorded magnetoencephalography (MEG) in humans, while participants performed a target identification task. Random-digit strings, with phrase-long chunks of two digits, were presented at chunk rates of 1.8 or 2.6 Hz, inside or outside the δ frequency band (defined here to be 0.5–2 Hz). Strong periodicities were elicited by chunk rates inside of δ in superior, middle temporal areas and speech-motor integration areas. Periodicities were diminished or absent for chunk rates outside δ, in line with behavioral performance. Our findings show that prosodic chunking of phrase-sized acoustic segments is correlated with acoustic-driven δ oscillations, expressing anatomically specific patterns of neuronal periodicities.
The Effect of Profitability, Liquidity, and Asset Structure on Capital Structure with Firm Size as Moderating Variable
Authors: Dewi Cicilia Ratna , Fachrurrozie Fachrurrozie 
Published: June 2021

The purpose of this research is to analyze the effect of profitability, liquidity, and asset structure on capital structure with firm size as a moderating variable. The population of this study was all property and real estate companies listed on the Indonesian Stock Exchange (IDX) from 2014-2016. The number of samples used was 39 companies with the audit of analysis of 117. This study used secondary data taken from the annual financial statements. The method of data analysis was descriptive analysis and Moderated regression analysis by difference absolute value test. The data analysis used was IBM SPSS Statistics 21. The result of the study showed that profitability, liquidity, and asset structure had negative and significant effects on capital structure. Firm size was able to moderates significantly the effect of liquidity on capital structure, but it is not able to moderate the effect of profitability and asset structure on the capital structure. The study concludes that capital structure is influenced by profitability, liquidity, and liquidity that moderated by firm size.
Keywords: Profitability; Liquidity; Asset Structure; Capital Structure; Firm Size
Analysis of the Effect of Fraud Pentagon Factors on Fraudulent Financial Statement with Audit Committee as Moderating Variable
Authors: Dewi Krisna , Anisykurlillah Indah 
Published: June 2021

This study aims to analyze the effect of fraud pentagon on fraudulent financial statements with audit committee as moderating variable. The population of this study was the property, real estate, and construction companies listed on the Indonesia Stock Exchange during 2016-2018. The sampling technique used purposive sampling and obtained 52 companies with 156 units of analysis. The data were analyzed using logistic regression analysis by IBM SPSS Ver.26. The results showed that company growth had a positive effect on fraudulent financial statements. Meanwhile, the effectiveness of supervision, quality of external auditors, the experience of directors, and CEO duality did not affect fraudulent financial statements. Audit committee significantly moderated the effect of company growth, the effectiveness of supervision, and the experience of directors on fraudulent financial statements. However, audit committee did not moderate the effect of quality of external auditors and CEO duality on fraudulent financial statements. This study concludes that the fraudulent financial statements will be higher when the company growth is higher. Audit committee weakens the effect of company growth, the effectiveness of supervision, and the experience of directors on fraudulent financial statements.
Keywords: Fraudulent Financial Statement; Fraud Pentagon; Audit Committee
Love of Money, Religiosity, and Gender: How do These Affect the Ethical Perceptions of Public Accountants?
Authors: Saadah Naili , Samroh Samroh 
Published: June 2021

Ethics has always been an interesting issue to discuss in any discussion related to the professionalism of the world of accounting and auditing. Public scepticism towards the accounting profession is quite reasonable since there are not a few auditors and public accountants involved with financial scandals. Money for an individual is like a double-edged knife, on the one hand, it is a need, but it can also be a root of greed, no exception for an auditor. Therefore, this study aims to determine the effect of love of money on the ethical perceptions of public auditors. Whether there is an influence of the love of money on the ethical perceptions of public auditors and how does this affect it when faced with one’s religiosity and gender. Using the object of the research of auditors who are members of the public accounting firm in Semarang city, this research succeeded in collecting a sample of 43 auditors with the criteria of having had at least three years of experience as an auditor. The results prove that love of money has a direct effect on the ethical perceptions of public auditors. However, when the feeling of love of money is faced with religiosity and gender, it does not significantly influence auditors’ ethical perceptions. Therefore, it can be concluded that love of money is one’s attitude in general which is reflected in the behaviour of an auditor so that one’s love of money can directly influence an auditor’s ethical perception.
Keywords: Love of Money; Religiosity; Gender; Ethical Perceptions
Home Visiting for NICU Graduates: Impacts of Following Baby Back Home
Authors: McKelvey Lorraine M. , Lewis Kanna N. , Beavers Jared , Casey Patrick H. , Irby Carmen , Goudie Anthony 
Published: June 2021

BACKGROUND AND OBJECTIVES
The Following Baby Back Home (FBBH) home visiting program supports families of high-risk low birth weight preterm infants after discharge from a hospital NICU. This study compares the health care use, immunization, and infant mortality rate of low birth weight preterm infants enrolled in FBBH with similar infants not in the program.

METHODS
From January 2013 to December 2017, 498 children enrolled in FBBH were identified in Arkansas vital statistics records and the Arkansas All-Payer Claims Database. Infants in FBBH were matched with children in a control group on the basis of demographics and medical conditions of the infant. Generalized linear mixed models with double propensity-score adjustment were used to estimate program effects.

RESULTS
In the first year after discharge and compared with a propensity-score matched cohort of control infants, those enrolled in FBBH were significantly more likely to have higher numbers of medical appointments and more compliant immunization history. The odds of dying in the first year of life for control infants was 4.4 times (95% confidence interval: 1.2–20.7) higher than those managed in the program.

CONCLUSIONS
A goal of the FBBH home visiting program is to work with parents to educate and support them as they care for their medically fragile infants. We conclude that education and support was instrumental in the infant health care use and outcome differences we observed during the first year of life.
ЕЛЕКТРОЛІЗ РОЗЧИНІВ NaCl В ПРОТОЧНИХ СИСТЕМАХ
Authors: В. Гиренко Дмитро , Б. Веліченко Олександр , Б. Шмичкова Олеся 
Published: June 2021

Досліджено електроліз розчинів NaCl у проточних системах. Показано, що для мінімізації перетворення гіпохлориту в хлорат на аноді та відновлення іонів гіпохлориту на катоді слід проводити електроліз з мінімальною швидкістю перемішування розчину відносно електродів. Видалення мембрани з комірки приводить лише до незначного зниження виходу за струмом гіпохлориту натрію в межах 1–3 % і незначного підвищення рН розчину, що позитивно впливає стабільність розчину. Вихід за струмом хлоратів не змінюється. Позитивним ефектом є зменшення напруги на комірці, що покращує енергетичну ефективність синтезу натрію гіпохлориту. В разі сили струму 2 А і використання двох проточних комірок за об'ємної швидкості потоку 8.7 л/год можна синтезувати високочистий розчин натрію гіпохлориту, що містить 500 мг/л NaClO і 0.6 мг/л NaClO3. Виходи за струмом натрію гіпохлориту та хлорату становлять 78 та 0.2 % відповідно. Електрохімічний реактор з трьома проточними елементами ємністю 9.2 л/год за струму 3 А дозволяє постійно отримувати розчин, що містить 1000 мг/л NaClO і не більше 6 мг/л NaClO3. Розроблені прототипи електролізерів успішно пройшли етапи лабораторних та експериментальних випробувань.