bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pregnancy After Laparoscopic Sleeve Gastrectomy (LSG): The Effect of Gestational Weight Gain (GWG) On Pregnancy and Perinatal Outcomes
Authors: SANCAK Seda , ÇELER Özgen , ÇIRAK ELİF , ÖZDEMİR ALİ , OKUROĞLU NALAN , BULUT NURİYE ESEN , FERSAHOĞLU MEHMET MAHİR , KARİP AZİZ BORA , AYDIN MEHMET TİMUÇİN , ÇİĞİLTEPE HÜSEYİN , ALTUN HASAN , MEMİŞOĞLU KEMAL 
Published: July 2021

Abstract
Introduction: We aimed to evaluate the effect of gestational weight gain (GWG) according to Institute of Medicine (IOM) recommendation after laparoscopic sleeve gastrectomy (LSG) on maternal and fetal outcomes.Materials and methods: A retrospective, observational study on the medical charts of pregnant women who had previously undergone LSG between 2012 and 2020. According to IOM, GWG was grouped as insufficient, appropriate, and excessive.Results: 82 pregnancies were included in this study. GWG was appropriate in 19 of the pregnancies (23%) and was insufficient in 18 (22%) and excessive in 45 (55%) of the cases. The time from operation till conception of excessive group is significantly longer than insufficient and appropriate group (p1:0.000; p2:0.029; p<0.05). There was no statistically significant difference between the groups regarding birthweight, gestational age, cesarean deliveries (CD), preterm birth, whether their child was small or large for their gestational age. There was no difference between mean hemoglobin, anemia, low ferritin level and ferritin level at early pregnancy and predelivery between groups (p<0.05). There was no significant correlation between the time from operation till conception, birthweight and gestational age. There was no significant correlation between body mass index (BMI) at conception, birthweight and gestational age. There was no significant correlation between early and predelivery ferritin and hemoglobin and birthweight and gestational age. There was no correlation between mean GWG and mean BMI at conception between birthweight in either study group. Conclusion: The gestational weight gain (GWG) did not impact maternal and neonatal outcomes.
Spatiotemporal Evolution of Chlorophyll-a Concentration From MODIS Data Inversion in the Middle and Lower Reaches of the Hanjiang River, China
Authors: Chen Zhuo , Dou Ming , Xia Rui , Li Guiqiu , Shen Lisha 
Published: July 2021

Abstract
The global construction of water projects has led to a clear trend of river and lake reservoir formation, spurring increasingly serious ecological environmental deterioration, especially that caused by the frequent occurrence of water blooms. Because of monitoring technology limitations, monitoring the algae content index in water has lagged behind the conventional water quality index, which makes sample monitoring too sparse in many rivers and the monitoring data incoherent, so it cannot truly reflect the evolution of water eutrophication. With moderate resolution imaging spectroradiometer (MODIS) remote sensing data monitoring, continuous chlorophyll-a observation data can be collected effectively. This method has important guiding significance for the early warning and control of water blooms. This study considers the middle and lower reaches of the Hanjiang River in China, based on the current remote sensing communication technology, MODIS remote sensing data, and statistical methods and measured chlorophyll-a concentration correlation analysis. Through the use of the trial and error method to establish the band ratio model and BP neural network model, two types of model errors were compared to determine the optimal algorithm settings for the middle and lower reaches of the Hanjiang River chlorophyll-a inversion. Subsequently, the algorithm model for 2000 to 2011 in the middle and lower reaches of the Hanjiang River chlorophyll-a concentration inversion and the results of the inversion analysis of spatiotemporal evolution characteristics we used to determine the influence of various environmental factors on the chlorophyll-a concentration change.
Adapting Supportive Care Guidelines from High-income Countries; Real World Data on Approach to Neutropenic Sepsis in Haemato-Oncology Patients in Sri Lanka
Authors: Hewamana Saman , Skandarajah Thurairajah , Jayasinghe Chathuri , Deshapriya Samadhi , Senarathna Dhananjani , Gayashan Dilip , Peiris Natasha , Perera Eranga , Harischandra Mahesh , Somiah Surjit , Munasinghe Nihal , Hewawasam Sangeetha , Arseculeratne Gehan , Wadanamby Rohini , Galagoda Geethani , Balawardena Jayantha 
Published: July 2021

Abstract
BackgroundSepsis is the main cause of non-relapse mortality and there are no published data on applicability of supportive care protocols from high-income countries in Sri Lanka. The aim of the study was to investigate management and mortality of neutropenic episodes among Haemato-Oncology patients. MethodsWe analysed retrospectively clinical characteristics, management, morbidity and mortality of neutropenic adult Haemato-Oncology patients from 01.01.2019 to 31.12.2019. ResultsA total of 169 neutropenic episodes were identified; 115 (68%) of such episodes were related to chemotherapy. Acute leukaemia, Lymphoproliferative disorders and Plasma cell disorders accounted for 23%, 69% and 8% of patients respectively. The median age of patients who had sepsis was 56 while that of those who had no sepsis was 53 (p-value 0.49). Median time to neutropenia was 9 days for those in the sepsis group compared to 8 days in the group that had no sepsis (0.64). Median neutrophil count in the group who had sepsis was 0.06 while it was 0.69 in the group that had no sepsis (p-value 0.000). Median time to commencement of antibiotics was 20 minutes. There were no deaths in the group of chemotherapy induced neutropenic sepsis. ConclusionThis is the only documented study relating to outcome and successful applicability of western supportive care protocols to Sri Lankan patients with neutropenia. In this study we have shown that survival data comparable to developed countries can be achieved in the setting of limited resources with service development, following guidelines and staff training.
Cell Tracking of Adult Neural Stem Cells From The Subependymal Zone In Vitro Reveals Cell Type-Specific Impacts On Cell Cycle Progression By The Extracellular Matrix Molecule Tenascin-C
Authors: Schaberg Elena , Götz Magdalena , Faissner Andreas 
Published: July 2021

Abstract
Adult neurogenesis has been described in two canonical regions of the adult central nervous system (CNS) of rodents, the subgranular zone (SGZ) of the hippocampus and the subependymal zone (SEZ) of the lateral ventricles. The stem cell niche of the SEZ provides a privileged environment composed of a specialized extracellular matrix (ECM) that comprises the glycoproteins tenascin-C (Tnc) and laminin-1 (LN1). In the present study, we investigated the function of these ECM glycoproteins in the adult stem cell niche. Adult neural stem cells (aNSPCs) of the SEZ were prepared from wildtype (Tnc+/+) and Tnc knockout (Tnc-/-) mice and analyzed using molecular and cell biological approaches. A delayed maturation of aNSPCs in Tnc-/- tissue was reflected by a reduced capacity to form neurospheres in response to epidermal growth factor (EGF). In order to examine a potential influence of the ECM on cell proliferation, aNSPCs of both genotypes were studied by cell tracking using digital video microscopy. aNSPCs were cultivated on three different substrates, namely poly-D-Lysine (PDL) and PDL replenished with either LN1 or Tnc for up to six days in vitro. On each of the three substrates aNSPCs displayed lineage trees that could be investigated with regard to cell cycle length. The latter appeared reduced in Tnc-/- aNSPCs on PDL and LN1 substrates, less so on Tnc that seemed to compensate the absence of the ECM compound to some extent. Close inspection of the lineage trees revealed a subpopulation of late dividing aNSPCslate that engaged into cycling after a notable delay. aNSPCslate exhibited a clearly different morphology, with a larger cell body and conspicuous processes. aNSPCslate reiterated the reduction in cell cycle length on all substrates tested, which was not rescued on Tnc substrates. When the migratory activity of aNSPC-derived progeny was determined, Tnc-/- neuroblasts displayed significantly longer migration tracks. This was traced to an increased rate of migration episodes compared to the wildtype cells that rested for longer time periods. We conclude that Tnc intervenes in the proliferation of aNSPCs and modulates the motility of neuroblasts in the niche of the SEZ.
An Ultrahigh Narrowband Absorber Close to the Information Communication Window
Authors: Ali Wajid , Iqbal Shahid , Ullah Muhib , Wang Xiaoli 
Published: July 2021

Abstract
In this paper, we demonstrate a plasmonic ultrahigh narrowband perfect absorber, which realizes an absorption intensity of up to 99.99% in the near-infrared electromagnetic spectrum regime. Different dimensional effects on absorption properties are studied using computer simulation technology (CST) with finite element method (FEM) solver. For both transverse electric (TE) and magnetic (TM) polarization, the absorber shows high stability over a wide range of incident angles. This ultrahigh absorption is attributed to synergy effect of magnetic resonance and surface plasmon resonance. Furthermore, the sensitivity goes to 300 nm/RIU for various refractive indices of different analytes. Our proposed absorber working wavelength is very close to the communication window of information, therefore, except for remarkable sensing abilities, it can also be well utilized in optoelectronic applications like optical switching, amplifiers, and all-optical plasmonic modulators.
Insights Into the Proteomic Profile of Newly Harvested Corn and Metagenomic Analysis of the Broiler Intestinal Microbiota
Authors: Yin Dafei , Wang Youli , Wang Liqun , Wu Yuqin , Bian Xiaoyi , Aggrey Samuel E. , Yuan Jianmin 
Published: July 2021

Abstract
BackgroundThe use of newly harvested corn in feed causes wet droppings in broilers and increased feed cost which was termed as “new season grain problem”. The present study was conducted to evaluate the proteomic profile of newly harvested corn and the subsequent influence on intestinal microbiol community for broiler chickens. MethodsNewly harvested corn stored for either half a month (HM) or two months (TM) was used, and the pasting properties, total soluble sugars, and proteomic analysis technology was used to explore the influence of storage on natural aging corn properties. Additionally, seventy-two 7d Ross 308 male broiler chicken were fed with different stored corn. Apparent metabolizable energy (AME), digesta viscosity, intestinal morphology and microbiota were examined to explore the influence of feed corn storage on broiler chickens. ResultsPasting properties in the TM corn exhibited decreased viscoelastic properties. Proteomic studies found a total of 26 proteins that were differentially expressed between the two treatment groups. Proteins involved in starch and polysaccharides biosynthesis were upregulated in TM compared with HM. Chickens fed on TM diet had higher relative energy utilization compared to the HM birds. With increased corn storage, the relative digesta viscosity decreased significantly (P≤0.05). The total number of goblet cells and lymphocytes was lower in chickens fed the TM diet. The microbiota data showed that the TM chickens had decreased abundance of diarrheal bacteria such as Hungatella hathewayi and Bacteroides fragilis, and increased butyrate-producing bacteria such as Alistipes compared to the HM chickens. ConclusionsStorage of newly harvested corn induced the synthetic reaction of large molecules and changed the solubility of starch and protein with increasing soluble sugars and decreasing pasting properties that may improve the fermentation of intestinal microbiota, improve the energy utilization and protect gut health without the risk of diarrhea.
Bio-Electroreduction of Chromium (VI) using Immobilized Sulfate Reducing Bacteria on Conductive Microbial Cellulose Biocathode
Authors: Loloei Mahshid , Rezaee Abbas , Ghods Ghazaleh 
Published: July 2021

Abstract
The present study evaluated effect of conductive microbial cellulose (MC) biocathode as a carbohyrate biopolymer in hexavalent chromium bio-electroreduction using immobilized sulfate reducing bacteria (SRB). The morphology studies using SEM shows that the biofilm of SRB was formed a good density on the conductive microbial cellulose biocathode. The Brunauer, Emmett and Teller (BET) analysis revealed that the particle-size distribution in the conductive biocathode was 0.9 nm. The kinetic studies shows that the Cr (VI) removal process fallow of pseudo-first-order kinetics with a constant rate was 0.6 h− 1. The energy consumption of the bio-electroreduction system was 2.7×10− 2 kWh/m3. The EDXA spectrum of sediments showed the presence of chromium peak, indicating that Cr (VI) was reduced on the bio-resuction system. The obtained results indicate that proposed bio-electroreduction system using immobilized sulfate reducing bacteria on the conductive microbial cellulose biocathode could be an efficient method for chromium bio-reduction from wastewaters.
Morphological Traits Among the Enset (Ensete Ventricosum) Landraces and Cultural Use of the Landraces for the Livelihood of People in Southern Ethiopia
Authors: Tekalign Wondimagegnehu , Feleke Newarinesh 
Published: July 2021

Abstract
BackgroundEnsete ventricosum is an important food crop consumed in the form of Bulla and Kocho mainly used in the southern parts of Ethiopia for their sustainable livelihood and ensuring food security. Besides, it is used as animal feed, as well as a source of medicine and fiber. This study was undertaken on the morphological traits among the Enset (Ensete ventricosum) landraces and cultural use of the landraces for the livelihood of people in Mareka woreda, Dawro zone, southern Ethiopia. The study was carried out in purposively selected four kebeles of Mareka district’s Dawro zone.ResultsA total of 145 (20 purposively selected key informants and 125 randomly selected respondents) were interviewed using semi-structured interviews, and field observation was also used to collect ethnobotanical data. The morphological traits were measured according to IBPGR (International Board for Plant Genetic Resources) descriptors for Enset. The data were analyzed by using computer software SPSS v 16.0 as well as Excel 2010 spreadsheet. A total of 33 Enset landraces were identified from the study area. Farmers gave the name for their landraces based on the morphological trait and sources of planting material. Identified landraces were grouped into five clusters based on their morphological trait variability. Mean plant height, pseudostem height, and circumference, leaf size, and numbers have significant differences among clusters. Cluster number five had the highest mean in plant height, pseudostem height, and circumference and cluster number three had the lowest mean. The highest landrace richness was recorded from Ocha (3.18) while the lowest was from Guta (2.56). The most abundant landraces were Amiya, Hoeya, Boza, Yaka, Bothena, Ontha, Adinona, Shasha, and Keteriya in the Mareka district.ConclusionsThis study confirmed that the Dawro zone is rich in diversity of Enset, however, reduction in production and loss of some landraces was observed because of different factors. Therefore, attention must be given to the conservation and maintenances of Enset landraces by all the concerned bodies.
Sustainable Repairing and Improvement of Concrete Properties Using Bacterial Consortium Isolated From Egypt
Authors: Mahmoud Hala H. A. , Kalaba Mohamed H. A. , El-Sherbiny Gamal M.E. , Mostafa Abdelzaher E. A. , Ouf Mohamed E. A. , Tawhed Waleed M. F. 
Published: July 2021

Abstract
The small cracks in concrete constructions are inevitable due to deterioration during their service life throughout different load combination factors. In this study, we aimed to isolate, identify, and construct a bacterial consortium able to heal small cracks of concrete and enhance the different properties of concrete. Six isolates of bacillus, endospore-forming bacteria were isolated. There are only three isolates out of the six coded as NW-1, MK and NW-9 were showed the ability to produce urease enzyme and able to grow at 60°C with optimum growth at a temperature of 40°C. These isolates were survived in high pH, where isolate NW-1 was tolerated pH up to 11 with optimum growth at 10 while the isolates NW-9 and MK showed growth at pH 12 with an ideal growth at 10. CaCO3 production was observed by the three bacterial isolates whether in pure or mixed cultures (bacterial consortium) but the consortium consisting of MK and NW-9 was significantly the highest in productivity among them. Therefore, these two isolates were identified using 16s as Bacillus flexus MK-FYT-3 and Bacillus haynesii MK-NW-9 and deposited to GenBank under accession numbers MN965692 and MN965693 respectively. The effect of bacteria on some properties of concrete was studied, and the results showed that the compressive and tensile strengths of bio-concrete specimens were significantly increased by 31.29, 29 % after 7 days and 36.3, 39 % after 28 days of curing compared to control specimens. The results of permeability indicated that the bio-concrete specimens significantly showed less permeability than the control specimens by 21.1, 23.1% after 7 and 28 of curing, respectively. To determine the concrete density, Ultrasonic Pulse Velocity (UPV) test was performed, and the bio-concrete specimens gave higher values ​​than control specimens by 26 and 20% after curing for 7 and 28 days, respectively. Also, surface healing of concrete was observed visually, the bio-concrete showed white precipitates around and inside the cracks after 7 days, which led to almost complete sealing of concrete after 28 days of curing, while the control samples were showed only very slight deposits on the surface and away from the cracks. The micro-analysis of concrete samples using SEM and XRD were done. It was found that the bio-concrete specimens showed crystalline precipitate with different shapes under SEM, while no such deposits appeared in the control specimens. On the other hand, the XRD profile was explained the characteristic peaks of calcium carbonate in both the bio-concrete and the control specimens, but the peak intensity was higher in the bio-concrete than the control specimens. This reflects the effectiveness of bacterial consortium in repairing and preventing the concrete cracks from spreading in addition to improving the various properties of concrete leading to increasing its life and sustainability.
Pharmacological Therapy of 141 Client-Owned Cats with Feline Infectious Peritonitis with Mutian ® Xraphconn Adenosine Nucleoside Analogue and Prognostic Prediction of Their Clinical Outcomes
Authors: Katayama Masato , Uemura Yukina 
Published: July 2021

Abstract
Background: Feline infectious peritonitis (FIP) is a fatal disease caused by feline coronavirus or its mutated pathogen designated as FIP virus. The most common form of FIP is wet or effusive, with non- regenerative anemia and clinical signs of mainly non-specific, such as recurrent fever, anorexia and weight loss. Recently, promising results using new anti-viral drug for treating cats with FIP were observed, but identification of rescuable FIP has been still challenging. It is highly worth to identify infected cats possible to be saved by such an anti-viral agent.Methods: At the initial veterinarian’s examination, owner inquiry-based signalments, viral gene detection by PCR and representative laboratory tests for diagnosis of FIP including hematocrit, A to G ratio, total bilirubin, serum amyloid-A and α1-acid globulin of 141 cats with effusive FIP were compared with those of 28 non-FIP disease cats. Consequently, 116 of them were rescued by administration of anti-viral drug Mutian X and the residual 25 were deceased unfortunately under treatments. Clinical and laboratory indicators observed prior to initial medication were also evaluated statistically between survived and non-survived groups.Results: Expectedly, levels for a few items of signalments (appetitive and activity scores), hematocrit, A to G ratio, total bilirubin, serum amyloid-A, α1-acid globulin and viral gene were found to be distributed distinctively between 141 FIP and 28 non-FIP cats. In the comparison between survived and non-survived FIP cats, most of their parameters including levels for hematocrit, A to G ratio, serum amyloid-A, α1-acid globulin and viral gene were not statistically different. Interestingly, total bilirubin concentrations of survived FIP cats were declined significantly than those of non-survived, and similarly, body temperatures, appetitive and activity scores appeared to be higher probably in accordance with their physical condition.Conclusions: Several clinical and laboratory indicators were informative in diagnosis of effusive FIP. We have investigated that one of the quantitative markers, total bilirubin levels, tend to be distributed characteristically in rescuable cats with effusive FIP. Elevated levels of total bilirubin may be a prognostic risk factor for severe FIP, predicting no clinical benefit obtained by using Mutian X as a therapeutic agent.
Clinical Application of Vancomycin PPK Model in Patients with Neutropenia
Authors: Fu Xiangjun , Huang Li , Guo Li , Lin Liangmo 
Published: July 2021

Abstract
Background: To explore the clinical application of a population pharmacokinetics (PPK) model of vancomycin in patients with hematological diseases who developed neutropenia.Methods: Patients with neutropenia treated at the Department of Hematology in our hospital were included in the PPK model study. A nonlinear mixed effect modeling approach (NONMEM) was used to establish the PPK model of those patients. Monte Carlo simulation was also carried out. A total of 64 patients were divided into model group and non-model group for clinical application research. The model group was given the first dose of 1g q8h, and the non-model group was given 1g q12h as the empiric therapy; the follow-up dose adjustment was made according to the concentration results.Results: This two-compartment model showed good stability and accuracy. The average concentrations in the model group and the non-model group were significantly different, i.e., 13.45±4.07 μg/ml, 60.71% reaching the target concentration vs. 9.85±3.76 μg/ml, 27.78% reaching the target concentration, respectively (all P<0.05). This suggested that for patients with neutropenia and CLCR≥90 ml/min/1.73m2, the first dose of 1g q8h may help to reach the target concentration as soon as possible.Conclusions: Our PPK model of vancomycin in patients with hematologic diseases who developed neutropenia can be used to realize the individualized application of vancomycin in this population.