bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Smartphone App haMSter for Tracking Patient-Reported Outcomes in People With Multiple Sclerosis: Protocol for a Pilot Study
Authors: Altmann Patrick , Hinterberger Werner , Leutmezer Fritz , Ponleitner Markus , Monschein Tobias , Zrzavy Tobias , Zulehner Gudrun , Kornek Barbara , Lanzenberger Rupert , Berek Klaus , Rommer Paulus Stefan , Berger Thomas , Bsteh Gabriel 
Published: March 2021

Background
Treatment and monitoring decisions in people with multiple sclerosis (MS) are based commonly on clinician-reported outcomes. These reflect physical and radiological disease activity and are the most relevant endpoints in clinical trials. Over the past few years, the number of studies evaluating so-called patient-reported outcomes (PROs) has been increasing. PROs are reports from patients concerning their own health perception. They are typically obtained by means of questionnaires and aim to quantify symptoms such as fatigue, depression, and sexual dysfunction. The emergence of PROs has made a tremendous contribution to understanding the individual impact of disease in people with MS and their health-related quality of life. However, the assessment of PROs consumes resources, including time and personnel. Thus, useful ways to conveniently introduce PROs into clinical practice are needed.

Objective
We aim to provide a rationale and pilot study protocol for a mobile health (mHealth) solution named “haMSter” that allows for remote monitoring of PROs in people with MS.

Methods
The core function of haMSter is to provide three scientifically validated PRO questionnaires relevant to MS for patients to fill out at home once a month. Thereby, longitudinal and remote documentation of PROs is enabled. A scoring algorithm graphically plots PRO scores over time and makes them available at the next visit.

Results
The pilot study is currently ongoing and will evaluate adherence to this mHealth solution in 50 patients over a period of 6 months. Results from the haMSter pilot study are expected in 2021.

Conclusions
haMSter is a novel mHealth-based solution for modern PRO research, which may constitute the first step in achieving the ability to integrate PROs in clinical practice. This allows for a more problem-oriented approach in monitoring visits, which addresses patient needs and ultimately saves time.

Trial Registration
ClinicalTrials.gov NCT04555863; https://clinicaltrials.gov/ct2/show/NCT04555863

International Registered Report Identifier (IRRID)
DERR1-10.2196/25011
Migración de una modalidad a otra durante la pandemia
Authors: Cavazos Salazar Rosario Lucero 
Published: March 2021

El presente trabajo presenta el proceso realizado por la Universidad Autónoma de Nuevo León (UANL) ante la pandemia del coronavirus SARS-CoV-2, en el cual se realizó una restructuración sobre la estrategia enseñanzaaprendizaje que transforma y crea un movimiento migratorio de la educación presencial a la educación virtual, abriendo así un nuevo paradigma educativo. Se postula como un ejemplo de los retos y soluciones potenciales que enfrentan las instituciones educativas en México y el mundo. Ante la nueva normalidad, la UANL crea un proyecto denominado Estrategia de educación digital , el cual busca crear, implementar y mejorar el espacio de comunicación y aprendizaje entre maestros y alumnos, utilizando tanto recursos didácticos digitales como herramientas tecnológicas, con el fin de transformar y habilitar los procesos de enseñanza-aprendizaje dentro del ámbito educativo.
DAMPAK TINGGAL ATAU BEKERJA DI LINGKUNGAN PERTAMBANGAN DAN INDUSTRI TERHADAP KEJADIAN TUMOR GANAS
Authors: Marissa Nelly , Fitria Eka , Nur Abidah , Ichwansyah Fahmi 
Published: March 2021

Perkembangan pertambangan dan perindustrian selain meningkatkan ekonomi masyarakat juga memberi dampak terhadap kesehatan, diantaranya adalah meningkatnya kejadian kanker. Tujuan penelitian ini adalah untuk mengetahui kejadian kanker pada pekerja dan penduduk di lingkungan pertambangan dan perindustrian. Penelitian observasional analitik ini menggunakan desain cross sectional. Penelitian ini dilakukan dengan menganalisis data riset penyakit tidak menular tahun 2016. Populasi dalam penelitian ini adalah perempuan usia 25-64 tahun yang tinggal di wilayah perkotaan di 76 kabupaten/kota, 34 provinsi di Indonesia. Total, 4398 peserta direkrut sebagai sampel menggunakan kuota sampling. Data dikumpulkan dengan teknik wawancara menggunakan kuesioner. Chi Square digunakan untuk menganalisis data menggunakan SPSS 23. Hasilnya menunjukkan bahwa tinggal di kawasan industri berhubungan dengan kejadian kanker terhadap perempuan (p = 0,009). Penderita kanker telah tinggal di kawasan industri lebih dari 30 tahun, kebanyakan tinggal di kawasan industri phthalate, jarak tempat tinggal dengan kawasan industri ≤ 5 km, industri bersifat khusus, dan kebanyakan responden yang menderita kanker menggunakan air dari sumur-bor/pompa/gali/PDAM. Tinggal dalam waktu yang lama dan jarak yang dekat dengan dengan kawasan industri meningkatkan resiko terhadap kanker pada perempuan.

The development of mining and industry besides improving community economic also has an impact on health, such as cancer. The purpose of this study was to determine the incidence of cancer in workers and residents in the mining and industrial environment. This analytic observational study used a cross sectional design. This research was conducted by analyzing data from non-communicable disease research in 2016. The population in this study were women aged 25-64 years living in urban areas in 76 districts / cities, 34 provinces in Indonesia. In total, 4398 participants were recruited as samples using quota sampling. Data were collected by interview technique using questionnaire. Chi Square was used to analyze data using SPSS 23. The results showed that living in industrial areas was associated with cancer incidence of women (p = 0.009). Cancer patients have lived in industrial area for more than 30 years, mostly living in phthalate industry, distance of residence with industrial area ≤ 5 km, specific industry, and most respondents suffering from cancer use water from wells-drill /pump/PDAM. Staying for long periods of time and close proximity to industrial areas increases the risk of cancer in women.
PENGARUH VARIASI DOSIS PUPUK ORGANIK LIMBAH CAIR NANAS (LCN) TERHADAP PERTUMBUHAN DAN PRODUKSI TANAMAN SELADA
Authors: Muarif Moh , Sujarwanta Agus , Santoso Handoko , Muhfahroyin Muhfahroyin 
Published: March 2021

Abstract: This research is an experimental research, which aims to determine the effect of variation dosage in of organic pineapple liquid waste fertilizer, on the growth and productivity of red lettuce (Lactuca Sativa L) and its potential as learning resources of biology learning. This research uses a Completely Randomized Design with 1 control and 3 treatment combinations and 5 repetitions. This research was conducted for 30 days. The parameters which is used in this research include plant height and wet weight of lettuce (Lactuca sativa L), with supporting data in the form of number of leaves and stem diameter. The main data is tabulated and analysed using the SPSS 25.0 application which includes Multivariate Analysis of Variance. The results of this research can be concluded that the application of organic fertillizer from pineaplle liquid waste has a significant influence on the growth and product of lettuce (Lactuca sativa L). The results of the research be used as a practical guide on plant growth and development materials.
European spatial planning beyond sovereignty
Authors: Faludi Andreas 
Published: March 2021

By definition sovereign, States find themselves inescapably in a situation of permanent competition. Moreover, given that an inherent quality of sovereignty is to exclude obeying whomever else, nobody, neither individuals nor institutions can arbitrate between them. This being the case, in the international arena power becomes the one and only currency. It seems basic even to each State’s survival: in this endless competition, the sustainability of each depends on the capacity to maintain a sufficient level of power.
(Badie, 2018, p.44 translated by the author)
What is ... needed is reflecting on new ways of adapting politics and democracy to the unique and universal world of networks...
(Balligand and Maquart, 1990, p.219 translated by the author)

The above quotes relate to the ambivalence of its members towards the European Union construct. Wishing to remain sovereign, they simultaneously acknowledge that they have to adapt to a new world. So, they conclude treaties which give the Union specific powers. Unable to unilaterally give itself powers, or ‘competences’ in EU jargon, their Union is therefore ‘intergovernmental’. If it were able to assume powers on its own, it would be like a federal state. As such, the Union could exercise some degree of ‘territoriality’, or control over its borders. As it is, it cannot.
Development of ATmega 328P micro-controller emulator for educational purposes
Authors: Šipoš Michal , Šimoňák Slavomír 
Published: March 2021

Abstract
The paper presents some of our recent results in the field of computer emulation for supporting and enhancing the educational processes. The ATmega 328P micro-controller emulator has been developed as a set of emuStudio emulation platform extension modules (plug-ins). The platform is used at the Department of Computers and Informatics as a studying and teaching support tool. Within the Assembler course, currently, the Intel 8080 architecture and language is briefly described as a preliminary preparation material for the study of Intel x86 architecture, and the Intel 8080 emuStudio emulator module is used here. The aim of this work is to explore the possibility to enrich the course by introducing a more up-to-date and relevant technology and the ATmega is the heart of Arduino – a popular hardware and software prototyping platform. We consider the options to make the process of studying the assembly language principles more attractive for students and using the ATmega AVR architecture, which is broadly deployed in embedded systems, seems to be one of them.
Statistical complexity of the kicked top model considering chaos
Authors: Fülöp Ágnes 
Published: March 2021

Abstract
The concept of the statistical complexity is studied to characterize the classical kicked top model which plays important role in the qbit systems and the chaotic properties of the entanglement. This allow us to understand this driven dynamical system by the probability distribution in phase space to make distinguish among the regular, random and structural complexity on finite simulation. We present the dependence of the kicked top and kicked rotor model through the strength excitation in the framework of statistical complexity.
Emergence of Illegality in the Underlying Contract as an Exception to the Independence Principle of Demand Guarantees
Authors: Kelly-Louw Michelle , Lupton Cayle 
Published: March 2021

It is questionable whether illegality in the underlying contract of a demand guarantee can or should constitute a valid exception to this instrument’s independence (autonomy) principle. From earlier English case law and scholarly discussions it appears that the acceptance of such an exception is contentious and, even if it is recognised, its extent remains uncertain. The English courts have previously indicated that they are open to accepting illegality in the underlying contract as an exception to the principle of independence of demand guarantees, but have not developed the exact parameters of such an exception. In the past, there were no South African court cases where illegality in the underlying contract was accepted, or even considered, as a possible exception to the independence principle of a demand guarantee. In a recent South African case, Mattress House (Proprietary) Ltd v Investec Property Fund Ltd, we find the first evidence of a South African High Court’s willingness to accept the possibility of illegality in the underlying contract as constituting a valid exception. In this article we discuss this South African case, which provides general guidance on the possibility of accepting such an exception under the South African law. South Africa is always persuasively influenced by English law in relation to demand guarantees. Therefore, we also discuss the English law.
Caries Experience among Tribal Gypsies in Thoothukudi District - A Cross-Sectional Study
Authors: Lalitha Rani Chellappa  , Leelavathi L  , Pradeep Kumar Rathinavelu  , Meignana Arumugham Indiran  
Published: March 2021

Dental caries, or tooth decay, is an infectious process involving breakdown of the tooth enamel. Caries form through a complex interaction between cariogenic acid-producing bacteria in combination with fermentable carbohydrates and other dietary, genetic, behavioural, social, and cultural factors. Poor oral hygiene and low dental service levels were found in marginalised areas. The study aimed to assess the caries experience of Narikuravars in Thoothukudi district. A cross-sectional study was done among gipsies in Thoothukudi district. Oral health examination was done the gipsies in the above three taluks in which they were present. All the study participants were examined under adequate illumination, and clinical data were collected on dental caries as described by the World Health Organization (WHO). DMFT (Decayed, Missing and Filled teeth) was used to assess the caries experience. For statistical analysis, t-test and ANOVA was used. The total size of the screened population was 164. There were 128 adults and 36 children who are below 18 years of age. Mean Decayed teeth, mean Missed teeth and mean Filled teeth was found to be 3.38±1.730, 1.01± 2.109, 0.01± 0.088 respectively. Decayed teeth were most common in the study population. Mean DMFT score among the adult study population was found to be 4.40 ± 2.603. The difference between the different age groups to Mean DMFT and was found to be statistically significant (F value- 22.679; p < 0.05). The present study concluded that the experience of dental caries was low in the study population. It was more prevalent in males as compared to the female population.
Kajian Batasan Nilai Faktor Air Semen pada Campuran Beton di Lingkungan Korosif
Authors: Rulian Nizar Farhan , Saelan Priyanto 
Published: March 2021

ABSTRAKBeton adalah material konstruksi yang pada saat ini sudah sangat umum digunakan. Saat ini berbagai bangunan sudah menggunakan material dari beton. Pentingnya peranan konstruksi beton menuntut suatu kualitas beton yang memadai, beton tidak hanya digunakan di darat melainkan dapat digunakan juga di dalam air laut. Beton yang berada pada lingkungan korosif atau beton yang terendam air laut nilai faktor air-semennya dibatasi oleh SNI. Nilai maksimum faktor air-semen pada lingkungan air laut yaitu sebesar 0,45. Tujuan penelitian ini adalah untuk mengetahui apakah nilai faktor air-semen masih dapat diperbesar lagi melebihi batas maksimal menurut SNI sesuai dengan kekuatan dan ketahanan yang dapat digunakan pada beton yang terendam air laut. Metodologi ini adalah dengan mengumpulkan data sekunder tentang pengaruh faktor air-semen pada beton yang dirawat menggunakan air laut. Penelitian ini memprediksikan permeabilitas yang berada pada air laut dengan variasi faktor air-semen yaitu sebesar 0,40; 0,50; dan 0,60. Kesimpulan penelitian ini adalah faktor air-semen dapat diperbesar sampai dengan 0,50 apabila umur rencana bangunan 50 tahun.Kata kunci: beton, permeabilitas, faktor air semen ABSTRACT
Perbandingan Peta Gempa pada Analisis Potensi Likuefaksi (Studi Kasus Jalan Tol Ruas Probolinggo – Banyuwangi Seksi II)
Authors: Amri Ahmad Faisal , Ikhya Ikhya 
Published: March 2021

ABSTRAKProbolinggo Jawa timur memiliki sesar yang berpotensi akan terjadinya gempa. Sesar Probolinggo bergerak sebesar 0,2 mm per tahun. Pasir lepas yang terdapat pada jalan tol Probolinggo – Banyuwangi ini sebagai salah satu indikasi potensi likuefaksi. Analasis potensi likuefaksi menggunakan metode Seed et al (1985). Analisis potensi likuefaksi pada tanah ini menggunakan beberapa peta gempa dan variasi fines content pada tanah. Perbedaan percepatan gempa dan fines content pada beberapa peta gempa tersebut akan menunjukan pengaruh pada potensi terjadinya likuefaksi pada tanah. Hasil penelitian tanah dengan kandung fines content 35 % terjadi likuefaksi lebih sedikit dibanding tanah dengan kandungan fines content yang lebih kecil. Hal tersebut terjadi karena nilai fines content berpengaruh pada hasil CRR. Peta gempa dengan periode ulang lebih besar memiliki percepatan gempa besar sehinnga terjadi titik likuefaksi lebih banyak dibanding peta gempa dengan periode ulang lebih kecil. Hal tersebut terjadi karena percepatan gempa berpengaruh pada nilai CSR.Kata Kunci: CSR, CRR, fines content, likuefaksi, percepatan gempa ABSTRACTProbolinggo, East Java has a fault that has the potential to cause an earthquake. The Probolinggo Fault moves by 0.2 mm per year. The loose sand found on the Probolinggo – Banyuwangi toll road is an indication of the potential for liquidation. Analysis of the potential for liquefaction using the method of Seed et al (1985). Analysis of the potential for liquefaction on this land using several earthquake maps and variations in soil content. The difference in earthquake acceleration and fines content on some earthquake maps will show the effect on the potential occurrence of liquefaction on the ground. The results of soil research with 35% fines content have fewer liquefaction compared to soil with smaller fines content. This happens because the value of fines content affects the CRR results. Earthquake maps with greater return periods have large earthquake acceleration so that there are more liquefaction points than earthquake maps with smaller return periods. This happens because the earthquake acceleration affects the value of CSR.Keywords: CSR, CRR, fines content, liquefaction, earthquake acceleration
Analisis Kinerja Bangunan Rangka Baja dengan Bresing Tahan Tekuk terhadap Beban Gempa
Authors: Ilham Ilham 
Published: March 2021

ABSTRAKPenggunaan bresing tahan tekuk dapat menjadi solusi atas kebutuhan struktur tahan gempa di Indonesia. Disipasi energi pada elemen bresing tahan tekuk dilakukan melalui kinerja plastifikasi bagian inti bresing akibat beban tarik dan tekan. Penelitian ini berisi kajian kinerja dari bangunan rangka baja beraturan dengan bresing tahan tekuk (BRB) dengan variasi level ketinggian lantai yaitu 3 lantai, 8 lantai dan 15 lantai. Analisis struktur 3D dilakukan dengan dua prosedur analisis yaitu modal pushover dan nonlinear time history pada program ETABS. Hasil analisis menunjukkan bahwa pemilihan elemen BRB sangat mempengaruhi kinerja struktur, yang terlihat dari pola drift yang terjadi. Untuk struktur beraturan dengan berbagai ketinggian, tingkat kinerja struktur dengan BRB cukup baik, yaitu Immediate Occupancy (IO) akibat beban gempa rencana. Plastifikasi hanya terjadi pada BRB, dan kelelehan pada balok mulai terbentuk sampai mekanisme keruntuhan terjadi. Hasil modal pushover dengan nonlinear time history pada bangunan 15 lantai yang cukup mirip menunjukkan bahwa modal pushover dapat digunakan untuk memprediksi kinerja struktur BRB yang beraturan.Kata kunci: kinerja struktur, bresing tahan tekuk, immediate occupancy, modal pushover, nonlinear time history ABSTRACTBuckling restrained braces (BRB) can be an alternative solution for earthquake resistant steel structure in Indonesia. The energy dissipation for buckling restrained elements is conducted through yielding of the core due to tension or compression forces. This study presents an evaluation of the structural performance of steel structures with BRB varying in heights, 3-story, 8-story and 15-story. The 3D structural analysis was carried out with ETABS software using 2 methods, Modal Pushover and Nonlinear Time History. The results shows that the selection of BRB elements greatly affected the structural performance, showed by the drift pattern. For regular structures with variation in heights, structures with BRB behaved satisfactory under the design load with the performance level of Immediate Occupancy (IO). Yielding was limited to BRB members, and afterwards the yielding occurred on beams until collapse. The results of modal pushover and time history analysis for 15-story structure are similar, thus modal pushover can be used to predict the performance of regular structural system with BRB.Keywords: structural performance, buckling restrained brace, immediate occupancy, modal pushover analysis, nonlinear time history analysis
Analisis Stabilitas Timbunan pada Tanah Dasar Berbentuk Lereng dengan Metode Elemen Hingga
Authors: Fahmi Mufidhiansyah , Ikhya Ikhya 
Published: March 2021

ABSTRAKAnalisis menggunakan program PLAXIS 2D dengan tinggi timbunan dan kemiringan tanah dasar bervariasi tanpa dan dengan perkuatan rock fill sehingga diperoleh kebutuhan rock fill agar faktor keamanan memenuhi syarat. Hasil analisis dengan kemiringan tanah dasar 1V:8H diperoleh kebutuhan rock fill timbunan lempung dengan tinggi 5m, 10m, 15m dan 20m sebesar 0%; 24,7%; 45,5% dan 59,1% sedangkan timbunan pasir sebesar 14,5%; 43,2%; 62,4% dan 71,4%. Pada kemiringan tanah dasar 1V:6H diperoleh kebutuhan rock fill masing-masing ketinggian timbunan lempung sebesar 5%; 45,8%; 59,3% dan 66.6%, sedangkan timbunan pasir sebesar 33,1%; 62,3%; 71,9% dan 73,2%. Pada kemiringan tanah dasar 1V:4H diperoleh kebutuhan rock fill masing-masing ketinggian timbunan lempung sebesar 48,9%; 66,7%; 75,6% dan 81,3%; sedangkan timbunan pasir sebesar 60,1%; 72,6%; 80,5% dan 84%. Variasi jenis mesh menghasilkan faktor keamanan yang tidak signifikan antar jenis mesh dikarenakan lapisan timbunan yang dimodelkan relatif rapat. Analisis geometri tanah dasar bertangga dengan lurus tidak menunjukkan pengaruh yang signifikan terhadap faktor keamanan.Kata kunci: stabilitas lereng, timbunan, tanah dasar, rock fill, metode elemen hingga, PLAXIS 2D ABSTRACTAnalysis using PLAXIS 2D program with varying heights and slopes of subgrade without and with rock fill reinforcement in order to obtain the need for rock fill so that the safety factor meets the requirements. The results of the analysis with a subgrade slope of 1V: 8H obtained the need for rock fill clay pile with a height of 5m, 10m, 15m and 20m of 0%; 24.7%; 45.5% and 59.1% while the sand pile was 14.5%; 43.2%; 62.4% and 71.4%. At a subgrade slope of 1V: 6H, the required rock fill height for each clay pile is 5%; 45.8%; 59.3% and 66.6%, while the sand pile was 33.1%; 62.3%; 71.9% and 73.2%. At 1V: 4H subgrade slope, the required rock fill height for each clay pile height is 48.9%; 66.7%; 75.6% and 81.3%; while the sand pile was 60.1%; 72.6%; 80.5% and 84%. Variation of mesh types resulted in insignificant safety factor between mesh types because the modeled embankment layer was relatively tight. The geometry analysis of the straight stepped subgrade did not show a significant effect on the safety factor.Keywords: slope stability, embankment, subgrade, rock fill, Finite Element method, PLAXIS 2D