bluuebunny/crossref_metadata_2025_split huggingface dataset:
GERAKAN PENDIDIKAN ISLAM KONTEMPORER ORGANISASI NAHDLATUL WATHAN: KONSEP DAN PRAKSIS
Authors: Suparman  
Published: December 2021

Kajian Pendidikan Islam mencakup berbagai topik yang meliputi pemikiran, institusi, aktivitas, kebijakan, sampai pada ragam teori dan praktik atau dimensi konsepsi dan aplikasi. Mengingat bahwa pendidikan Islam telah berlangsung sejak era Rasulullah SAW. serta banyaknya karya tulis ulama’ klasik dan eksistensi institusi yang eksis hingga saat ini, maka substansi pendidikan Islam telah layak menjadi sebuah kajian tersendiri, bahkan memiliki teori dan konsep tersendiri pula. Maksudnya, ruang lingkup, konstruksi teoritis, dan aplikasi pendidikan Islam dengan terminologi lain, memenuhi syarat untuk membangun sebuah disiplin ilmu. Nahdlatul Wathan sebagai organisasi kemasyarakatan Islam telah memberikan andil kepada agama, nusa dan bangsa, dalam bidang pendidikan dan perannya membantu pemerintah mencerdaskan bangsa. Kebutuhan serta hajat masyarakat yang semakin besar dalam bidang pendidikan, tampaknya merupakan salah satu pendorong bagi Nahdlatul Wathan untuk berupaya meningkatkan dan mengembangkan diri dalam mengelola pendidikan. Pertumbuhan dan perkembangan pondok pesantren, madrasah, dan sekolah di lingkungan Nahdlatul Wathan terus mengalami peningkatan, baik jumlah dan jenis sekolah dan madrasah, tingkat atau jenjang pendidikannya, maupun kurikulum yang digunakan terutama yang berada di kelompok NWDI dan NBDI.
Perencanaan Persediaan Alat Tulis Kantor Di CV Surya Niaga Jaya
Authors: Hidayat Riyan , Saputra Juni , Oemara Syarif Amiroel 
Published: December 2021

CV Surya Niaga Jaya merupakan salah satu perusahaan yang bergerak dibidang supplier penjualan alat tulis kantor. CV Surya Niaga Jaya memiliki kendala terhadap pengelolaan persediaan yaitu terjadi kenaikan permintaan alat tulis kantor, untuk (reorder) mengalami masalah permintaan yang tidak terlayani harus menjadi perhatian bagi CV Surya Niaga Jaya karena hal ini akan berpengaruh pada terhambatnya kegiatan operasional penjualan. Dengan menggunakan metode peramalan (forecasting) dan EOQ (economic order quantity) sebagai teknik pemecahan permasalahan. Untuk dapat dilakukan analisa apabila ada terjadi penumpukan atau kekurangan persediaan, dan berapa jumlah safety stock dan maksimum stok yang harus disiapkan perusahaan untuk kelancaran produksi. Persediaan pena di CV Surya Niaga Jaya periode Januari 2021 adalah sebanyak 45 kotak, jumlah EOQ untuk pena adalah 26 kotak dengan 6 kotak safety stock dan maksimum stok 47 kotak. Pemesanan kembali sebesar 32 kotak dan untuk ROP adalah 7 kotak. Sedangkan untuk persediaan kertas di CV Surya Niaga Jaya periode Januari 2021 adalah sebanyak 128 kotak, jumlah EOQ untuk kertas adalah 45 kotak dan jumlah Safety Stock sebanyak 17 kotak dan untuk maksimum stok sebesar 105 kotak. Pemesanan kembali sebesar 62 kotak dan untuk ROP adalah 20 kotak.
A Critical Study of the Historiography of Imam Abu Abdullah Muhammad Al-Hakim Neshapuri
Authors: Akhtar Sohail 
Published: December 2021

Historiography considered and important intellectual work since the ancient Greek era. Herodotus is to be called as the father of historiography. Muslim started historiography with the writing of Quran and Hadeith. Among them one is Imam Hakim Neshapuri who is considered the marvelous intellectual and in the field of Historiography Imam Muhammad Hakim Neshapuri consider one of the most relay able Muslim Historians of the 4th century A.H. After the advent of Islam Muslims attracted to the field of historiography and gave Quran great attention to promote historical knowledge. Therefore, historiography became one the popular discipline of knowledge among the Muslims intellectuals in medieval period. Muslim Scholars worked Quran, Hadeith, Fiqah and historiography in all its aspect. Imam Muhammad Hakim Neshapuri is one of the Muslim’s intellectual who worked in the promotion of knowledge. Imam Neshapuri considered one of the authentic Muslims historians of fourth century A.H and all the later historians used his books as reference to the events of this age. This paper is an attempt to explore historical work of Imam Hakim Neshapuri and this paper highlights the life and work of Imam Hakim Neshapuri.
Compilation of ozonesonde observation over Schirmacher oasis east Antarctic from 1999-2007
Authors: LAL R.P. , RAM SURESH 
Published: December 2021

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Regular ozone profile measurement over Antarctica has been made by India Meteorological Department over Indian second station Maitri (70.7° S, 11.7° E) with the help of Indian electro-chemical ozonesonde. Ozone density in the vertical column of the atmosphere is computed with weekly ozone soundings taken throughout the year. During the month of September- October more frequent soundings were taken to study vertical profile of atmospheric ozone and features of ozone hole. The mean monthly and yearly variation of ozone and temperature from surface to 10 hPa has been computed and analyzed from the ozonesonde ascents for the period 1999 to 2007. The study has shown profound depletion in October and lesser but substantial depletion in September, in association with the ozone hole. Depletion is most pronounced between about 250 and 20 hPa in October, with maximum local ozone losses near 70 hPa & 100 hPa levels and in September at 70 hPa. Ozone correlations with temperature for several pressure levels have revealed new insights into the causes and extent of ozone change. Lowest annual mean temperature varies from -55 to -63 °C between 300 to 50 hPa in all the year. The temperature less than -80 °C in months of August & September at 70 hPa & 100 hPa levels and about -70 °C in month of October at 70 hPa & 100 hPa levels can be attributed as an indicator of ozone depletion in months of October
Study of winter fog over Indian subcontinent : Climatological perspectives
Authors: SAWAISARJE G.K. , Khare P , SHIRKE C.Y. , DEEPAKUMAR S. , NARKHEDE N.M. 
Published: December 2021

Fog is localized phenomenon where horizontal visibility is reduced to less than 1000 m due to suspension of very small water droplets in the air. In fact Fog is cloud at surface level. This phenomenon matters to us in our daily activities due to its effect on life, public health, road safety, and economic prosperity. Its knowledge is essential to meet critical societal needs. In India, radiation and advection fog are most common which occur mostly over north India in winter. This study presents results of spatial variability of average number of days having visibility less than 1000 m at 0300 UTC during winter season over Indian subcontinent (0° N-35° N and 60° E-100° E) using synoptic hour daily surface data. Analysis of Fog events based on half hourly METAR observations for winter months (December 2010-February 2011) at selected ICAO stations of India is also presented.

The monthly spatial variability of average number of days with fog having visibility less than 1000 m indicates presence of fog over Indo-Gangetic plains on an average of 7 to 10 days during December and more than 8 days during January. South Gangetic West Bengal is susceptible to fog during February. Seasonal variation of fog shows that there is prominence of fog over Indo-Gangetic plains on an average of more than 6.5 days. Significant incidences of foggy days occur over South Interior Karnataka and Coastal Karnataka has incidence of foggy days on an average of 6.5 days. North India is susceptible to dense fog on average of 2.5 days during the season while Gangetic West Bengal, West Rajasthan and adjoining parts of east Rajasthan and East Uttar Pradesh have occurrence of fog on an average of 3.5 days. Thick fog occurs on an average of 3 days over northern India during the winter season. Analysis of time series of air temperature, dew point temperature, dew point depression, visibility, zonal and meridional components of wind and its magnitude at selected ICAO stations indicate that visibility reduces to below 1000 m while light winds are southeasterly at Ahmedabad, northerly to northwesterly at Amritsar, northerly to northeasterly at New Delhi, westerly to southwesterly at Kolkata, Guwahati and dew point depression is below 3 °C during such conditions. Long period 1971-2010 analysis of visibility conditions less than 1000 m over Indian subcontinent shows Indo-Gangetic plains region to have average wind speed to be 0.6 m/s, air temperature in the range 9 °C to 15 °C during December-February at 0300 UTC. Long period 1971- 2010 analysis of relative humidity shows Indo-Genetic plains region to have relative humidity in the range 72% to 84% at 0300 UTC during December-February.
Studies of some genes of Bacillus subtilis MN99 local strains against plant diseases
Authors: Saraadanbazar Ariunaa , Mijidsuren Byambasuren , Banzragch Battur 
Published: December 2021

The objective of this study was the isolation and characterization of Bacillus subtilis local strains from the soil in Mongolia. These local strains of B. subtilis are showed to have high antagonistic activities against some plant pathogenic fungi and bacteria. Six strains of B. subtilis were isolated and characterized morphologically, physiologically and biochemically according the Bergey’s Manual of Systematic Bacteriology.
In order to identify species of the isolated strains, we amplified and sequenced 16S rRNA gene, essential funtinal genes bmyB, spoVG and srfAA, which are related to antagonistic activity of these strains. The sequences were aligned using CLASTALW multiple sequence alignment tool. Phylogenetic tree was drawn according to Maximum likelihood”method and “Tamura-Nei” model using “MEGA-X version 10.2.6 program.
Among all isolates of B. subtilis MN99 and 7/24 strains had higher antagonist activity against plant diseases. According to partial sequence of srfAA (620bp) gene of MN99, the local strain belongs to B. subtilis and partial sequence of bmyB (370bp), spoVG (22bp) gene of MN7/24 strain showed that the it belongs to B. atrophaeus species. All local strains of B. subtilis had bacillomycin synthesis gene, and B. subtilis MN99 strain had only surfactine synthesis gene, while did not have spore formation and hemolysis gene SpoVG.
LA DIMENSIONE METAFISICA DEL SUFISMO:UNO SGUARDO SULL’OPERA DI ALBERTO VENTURA
Authors: Leccese Francesco Alfonso 
Published: December 2021

Riassunto: L’analisi dello sviluppo del Il Sufismo ha svolto un ruolo di prim’ordine all’interno delle società islamiche sia da un punto di vista della religiosità popolare sia da un punto di vista sociale. Esiste tuttavia un aspetto più strettamente dottrinale del Sufismo che possiamo definire come metafisica sufi. In particolare, in Ibn ‘Arabī e nei maggiori esponenti della sua scuola si possono rintracciare alcune delle tematiche che hanno universalmente influenzato la dottrina sufi (waḥdat al-wuǧūd, al-insān al-kāmil, al-ḥaqīqa al-muḥammadiyya) e che hanno rivestono un’importanza centrale anche nell’elaborazione dottrinale di Aḥmad Sirhindi e della ṭarīqa Naqšbandiyya.
Abstract: The analysis of the development of Sufism has played a leading role within Islamic societies both from the point of view of popular religiosity and from a social point of view. However, there is a more strictly doctrinal aspect of Sufism that we can define as Sufi metaphysics. In particular, in Ibn ‘Arabī and in the major exponents of his school we can trace some of the themes that have universally influenced the Sufi doctrine (waḥdat al-wuǧūd, al-insān al-kāmil, al-ḥaqīqa al-muḥammadiyya) and which have they are also of central importance in the doctrinal elaboration of Aḥmad Sirhindi and of the ṭarīqa Naqšbandiyya.
A novel machine learning derived RNA-binding protein gene–based score system predicts prognosis of hepatocellular carcinoma patients
Authors: Zhang Qiangnu , Zhang Yusen , Guo Yusheng , Tang Honggui , Li Mingyue , Liu Liping 
Published: December 2021

Background
Although the expression of RNA-binding protein (RBP) genes in hepatocellular carcinoma (HCC) varies and is associated with tumor progression, there has been no overview study with multiple cohorts and large samples. The HCC-associated RBP genes need to be more accurately identified, and their clinical application value needs to be further explored.

Methods
First, we used the robust rank aggregation (RRA) algorithm to extract HCC-associated RBP genes from nine HCC microarray datasets and verified them in The Cancer Genome Atlas Liver Hepatocellular Carcinoma (TCGA-LIHC) cohort and International Cancer Genome Consortium (ICGC) Japanese liver cancer (ICGC-LIRI-JP) cohort. In addition, the copy number variation (CNV), single-nucleotide variant (SNV), and promoter-region methylation data of HCC-associated RBP genes were analyzed. Using the random forest algorithm, we constructed an RBP gene–based prognostic score system (RBP-score). We then evaluated the ability of RBP-score to predict the prognosis of patients. The relationships between RBP-score and other clinical characteristics of patients were analyzed.

Results
The RRA algorithm identified 30 RBP mRNAs with consistent expression patterns across the nine HCC microarray datasets. These 30 RBP genes were defined as HCC-associated RBP genes. Their mRNA expression patterns were further verified in the TCGA-LIHC and ICGC-LIRI-JP cohorts. Among these 30 RBP genes, some showed significant copy number gain or loss, while others showed differences in the methylation levels of their promoter regions. Some RBP genes were risk factors or protective factors for the prognosis of patients. We extracted 10 key HCC-associated RBP genes using the random forest algorithm and constructed an RBP-score system. RBP-score effectively predicted the overall survival (OS) and disease-free survival (DFS) of HCC patients and was associated with the tumor, node, metastasis (TNM) stage, α-fetoprotein (AFP), and metastasis risk. The clinical value of RBP-score was validated in datasets from different platforms. Cox analysis suggested that a high RBP-score was an independent risk factor for poor prognosis in HCC patients. We also successfully established a combined RBP-score+TNM LASSO-Cox model that more accurately predicted the prognosis.

Conclusion
The RBP-score system constructed based on HCC-associated RBP genes is a simple and highly effective prognostic evaluation tool. It is suitable for different subgroups of HCC patients and has cross-platform characteristics. Combining RBP-score with the TNM staging system or other clinical parameters can lead to an even greater clinical benefit. In addition, the identified HCC-associated RBP genes may serve as novel targets for HCC treatment.
MEDIA DAN PENCIPTAAN KEPANIKAN MORAL: ANALISIS WACANA KRITIS TERHADAP PEMBERITAAN PANDEMI COVID-19 DI TIRTO.ID
Authors: Benmetan Thomas , Setyowibowo Bhekti 
Published: December 2021

Penelitian ini dilakukan untuk melihat bagaimana pandemi coronavirus dikomunikasikan kepada publik melalui pemberitaan media serta kaitannya dengan konstruksi narasi kepanikan moral. Data yang digunakan dalam penelitian ini dikumpulkan dari pemberitaan media online tirto.id tentang pandemi coronavirus sepanjang Maret hingga Agustus 2020. Dengan menggunakan Analisis Wacana Kritis sebagai metode penelitian, terdapat beberapa temuan menarik dalam studi ini. Pertama, penciptaan narasi kepanikan moral terhadap pandemi coronavirus di Indonesia dilakukan tirto.id dengan cara membingkai berita secara sensasional dan menekankan pada aspek-aspek tertentu dari pandemi sebagai magnifikasi isu. Kedua, ditemukan juga bahwa kepanikan moral adalah sebuah fenomena akar rumput yang dieskalasi melalui masifnya pemberitaan media. Selain itu, studi ini menunjukkan bahwa pembentukan wacana yang ada merupakan manifestasi dari kuasa media untuk membentuk penerimaan publik terhadap pandemi coronavirus di Indonesia. Kesimpulan dari penelitian ini memberikan gambaran bahwa publikasi tirto.id tentang pandemi coronavirus di Indonesia adalah manifestasi dari kekuatan media dalam membangun narasi, memengaruhi pandangan publik dan mendikte informasi.
A General Method to Develop Highly Environmentally Sensitive Fluorescent Probes and AIEgens
Authors: Miao Rong , Li Jing , Wang Chao , Jiang Xuefeng , Gao Ying , Liu Xiaoling , Wang Dan , Li Xin , Liu Xiaogang , Fang Yu 
Published: December 2021

AbstractEnvironmentally sensitive fluorescent probes (including AIEgens) play pivotal roles in numerous biological studies. Many of these functional materials are developed based on the twisted intramolecular charge transfer (TICT) mechanism. However, the TICT tendency of dialkylated amino groups in biocompatible main‐stream fluorophores (i.e., coumarins and rhodamines) is weak, limiting their sensitivities. Herein, by replacing dialkylated amino donors with an N‐methylpyrrole group to enhance TICT, a simple and general method to engineer highly environmentally sensitive fluorescent probes is reported. This method yields a platter of colorful fluorescent probes that demonstrates outstanding polarity and viscosity sensitivity with large turn‐on ratios (up to 191 times for polarity and 14 times for viscosity), as well as distinct aggregation‐induced emission (AIE) characteristics. The utilities of these probes in both wash‐free bioimaging and protein detections are also successfully demonstrated. It is expected that this molecular design strategy will inspire the creation of many environmentally sensitive probes.
Smart Nano‐PROTACs Reprogram Tumor Microenvironment for Activatable Photo‐metabolic Cancer Immunotherapy
Authors: Zhang Chi , He Shasha , Zeng Ziling , Cheng Penghui , Pu Kanyi 
Published: December 2021

AbstractProtease inhibitors can modulate intratumoral metabolic processes to reprogram the immunosuppressive tumor microenvironment (TME), which however suffer from the limited efficacy and off‐targeted side effects. We report smart nano‐proteolysis targeting chimeras (nano‐PROTACs) with phototherapeutic ablation and cancer‐specific protein degradation to reprogram the TME for photo‐metabolic cancer immunotherapy. This nano‐PROTAC has a semiconducting polymer backbone linked with a cyclooxygenase 1/2 (COX‐1/2)‐targeting PROTAC peptide (CPP) via a cathepsin B (CatB)‐cleavable segment. CPP can be activated by the tumor‐overexpressed CatB to induce the degradation of COX‐1/2 via the ubiquitin‐proteasome system. The persistent degradation of COX‐1/2 depletes their metabolite prostaglandin E2 which is responsible for activation of immune suppressor cells. Such a smart PROTAC strategy synergized with phototherapy specifically reprograms the immunosuppressive TME and reinvigorates antitumor immunity.
The First Sulfate‐Pillared Hybrid Ultramicroporous Material, SOFOUR‐1‐Zn, and Its Acetylene Capture Properties
Authors: Sensharma Debobroto , O'Hearn Daniel J. , Koochaki Amin , Bezrukov Andrey A. , Kumar Naveen , Wilson Benjamin H. , Vandichel Matthias , Zaworotko Michael J. 
Published: December 2021

AbstractHybrid ultramicroporous materials, HUMs, are comprised of metal cations linked by combinations of inorganic and organic ligands. Their modular nature makes them amenable to crystal engineering studies, which have thus far afforded four HUM platforms (as classified by the inorganic linkers). HUMs are of practical interest because of their benchmark gas separation performance for several industrial gas mixtures. We report herein design and gram‐scale synthesis of the prototypal sulfate‐linked HUM, the fsc topology coordination network ([Zn(tepb)(SO4)]n), SOFOUR‐1‐Zn, tepb=(tetra(4‐pyridyl)benzene). Alignment of the sulfate anions enables strong binding to C2H2 via O⋅⋅⋅HC interactions but weak CO2 binding, affording a new benchmark for the difference between C2H2 and CO2 heats of sorption at low loading (ΔQst=24 kJ mol−1). Dynamic column breakthrough studies afforded fuel‐grade C2H2 from trace (1 : 99) or 1 : 1 C2H2/CO2 mixtures, outperforming its SiF62− analogue, SIFSIX‐22‐Zn.
Direct Observation of Ultrafast Proton Rocking in the BLUF Domain
Authors: Kang Xiu‐Wen , Chen Zijing , Zhou Zhongneng , Zhou Yalin , Tang Siwei , Zhang Yifei , Zhang Tianyi , Ding Bei , Zhong Dongping 
Published: December 2021

AbstractWe present direct observation of ultrafast proton rocking in the central motif of a BLUF domain protein scaffold. The mutant design has taken consideration of modulating the proton‐coupled electron transfer (PCET) driving forces by replacing Tyr in the original motif with Trp, in order to remove the interference of a competing electron transfer pathway. Using femtosecond pump–probe spectroscopy and detailed kinetics analysis, we resolved an electron‐transfer‐coupled Grotthuss‐type forward and reverse proton rocking along the FMN–Gln–Trp proton relay chain. The rates of forward and reverse proton transfer are determined to be very close, namely 51 ps vs. 52 ps. The kinetic isotope effect (KIE) constants associated with the forward and reverse proton transfer are 3.9 and 5.3, respectively. The observation of ultrafast proton rocking is not only a crucial step towards revealing the nature of proton relay in the BLUF domain, but also provides a new paradigm of proton transfer in proteins for theoretical investigations.
Comparison of aroma, aroma‐active, and phenolic compounds of crude and refined hazelnut oils
Authors: Kesen Songul , Sonmezdag Ahmet Salih , Kelebek Hasim , Selli Serkan 
Published: December 2021

AbstractHazelnut (Corylus avellanaL.) is an important shelled nut with its pleasant aroma. The refining process causes significant changes in the quality attributes of hazelnut oil. The aim of this study was to assess the aroma, aroma‐active, and phenolic compounds of the crude and refined hazelnut oils by using gas chromatography–mass spectrometry (GC–MS), GC–MS‐olfactometry (GC–MS‐O), and liquid chromatography–mass spectrometry (LC–MS/MS). The antioxidant capacities were also determined by DPPH and ABTS methods. Results showed that terpenes and aldehydes constituted a significant portion of the aroma profile. Refining process dramatically reduced the numbers (from 63 to 25) and amounts of aroma compounds (from 36,769 to 4461 μg/kg). Similarly, the numbers of aroma‐active compounds were reduced from 22 to 8 by the refining process. Their flavor dilution factors ranged from 2 to 1024 for crude oil and from 2 to 32 in the refined oil. As of the phenolics, five and two compounds were quantified in the crude and refined oil samples, respectively. In sum, the refining process had a considerable adverse effect on the aroma, aroma‐active, and phenolic constituents of the hazelnut oil; hence, the refining process has to be planned with minimal negative effect on its organoleptic properties.