bluuebunny/crossref_metadata_2025_split huggingface dataset:
Genetic background of sesquiterpene lactones biosynthesis in Asteraceae. A review
Authors: Sozoniuk Magdalena 
Published: November 2021

Asteraceae family is a rich source of many sesquiterpene lactones (STLs). These secondary metabolites exhibit multidirectional activity including anti-tumor, anti-inflammatory or antimicrobial, just to name a few. Promising approach of metabolic engineering offers a way of increasing the production of STLs by reconstruction of their biosynthetic pathway in a heterologous system. Moreover, their production in host plants might be increased through overexpression of biosynthetic genes and/or transcription factors (TFs) positively regulating the pathway. Either of the strategies requires extensive knowledge on the genetic background of STLs biosynthesis pathway. This review summarizes molecular investigations concerning biosynthesis of these medicinally essential metabolites.
Nuevas pistas para comprender la gastrosquisis. Embriología, patogénesis y epidemiología
Authors: Chuaire-Noack Lilian 
Published: November 2021

La gastrosquisis es un defecto estructural congénito de la pared abdominal, localizado con mayor frecuencia a la derecha del ombligo, a través del cual sobresalen las vísceras abdominales. Durante mucho tiempo, sus aspectos evolutivos, etiológicos y epidemiológicos han sido un tema candente de controversia, aunque hallazgos recientes sugieren la participación de alteraciones genéticas, cromosómicas, y la existencia de una vía patogénica inductora de estrés, en la que factores de riesgo como los demográficos y ambientales pueden converger.
Con el objetivo de ampliar la frontera del conocimiento sobre una malformación que ha mostrado una creciente prevalencia global, hemos efectuado una revisión que incluye información, del desarrollo embrionario de la pared corporal ventral, el intestino primitivo, el complejo anillo-cordón umbilical, y de las teorías acerca de su origen, patogénesis e información epidemiológica reciente.
Analysis of the experience of the geriatric fracture program in two institutions in Colombia: a reproducible model?
Authors: Olarte Carlos Mario , Zuluaga Mauricio , Guzman Adriana , Camacho Julian , Lasalvia Pieralessandro , Garzón-Orjuela Nathaly , Prieto Laura , Nuñez Carmen Elisa , Acuña Jose , Mejía Alejandro , García Maria Claudia 
Published: November 2021

Background: hip fracture is the major cause of morbidity and mortality. Geriatric fracture programs promise to improve the quality of care, health outcomes and reduce costs.
Objective: To describe the results related to the Geriatric fracture programs implementation in two Colombian institutions. These results could then be compared to other published experiences to assess reproducibility of the program.
Methods: A retrospective descriptive study of the patients treated under the Geriatric fracture programs in two institutions in Colombia was carried out. The information of each institution was collected from the initial year of program implementation until 2018. Demographic characteristics, length of stay, hospitalization complications, readmissions and mortality were described. Consumption of healthcare resources was defined using base cases determined with local experts and costs were estimated using standard methods.
Results: 475 patients were included in the Geriatric fracture programs in two institutions. We observed an increase in the number of patients during the Geriatric fracture programs. The length of stay decreased between 8.5% and 26.1% as did the proportion of total complications, with delirium having the greatest reduction. A similar situation was seen for first year mortality (from 10.9% to 4.7% in one institution and form 11.4% to 5.1% in the other), in-hospital deaths and readmissions. Estimates of costs of stay and complications showed reductions in all scenarios, varying between 22% and 68.3% depending on the sensitivity scenario.
Conclusions: The present study presents the experience of two institutions that implemented the Geriatric fracture programs with increase in the number of patients treated and reductions in the time of hospital stay, the proportion of complications, readmissions, mortality, and estimated costs. These are similar between both institutions and with other published implementations. This could hint that geriatric fracture program may be implemented with reproducible results.
Geomorphosite Assessment at North Karangsambung -Karangbolong Geopark Kebumen, as Tools of Geotourism Development
Authors: Ansori Chusni , Warmada I. Wayan , Setiawan Nugroho Imam , Yogaswara Herry 
Published: November 2021

Geopark is a sustainable regional development concept that combines geological, biological, and cultural diversity through conservation and education activities to improve the community's welfare. Kebumen Regency has a National Geopark Karangsambung-Karangbolong (GNKK) covering 543,599 Km2 with 41 geosites, ten cultures, and eight biosite since 2018. The northern part of the area is a geological heritage that is widely used for field geological education.
The study aims to identify and assess geosites and geomorphosite in the north area, describing the region's geomorphological processes and geological evolution. Field research was conducted to get an overview of geological diversity, geomorphology, and geosite and determine the selected geomorphosite. Geomorphosite assessment is done quantitatively using the Kubalikova method by assessing five main parameters that include; Intrinsic and scientific value, the value of education, economic value, conservation value, and added value.
The scientific and intrinsic value of Pentulu Indah (PI) = 4, while Wagirsambeng = 3. Educational value of PI = 4, while Wagirsambeng = 2. Economic value is still not satisfactory, but P.I. = 2, while Wagirsambeng = 1.5. Conservation value of P.I. = 3.5, while Wagirsambeng = 2.5. Added value PI = 2.75 while Wagirsambeng = 1.5. Based on those, geomorphosite Pentulu Indah is 16,26 point or a good value (87.83 %) while Wagirsambeng is 10.5 point or fairly level (56.75 %).
Legal Aspects of Urban Climate Change Adaptation
Authors: Stupazzini Riccardo 
Published: November 2021

Much of the climate discourse of today is held the reduction of greenhouse gases (GHG) emissions and reducing humanity’s ecological footprint on Earth. However, as climate change is already impacting our planet, adaptation measures to climate change are also required. Rising temperatures, the multiplication of intense precipitation events and related pluvial and river floods, drought events and water scarcity, the increase of frequency of wildfires represent a few of the multiple climate change impacts that governments and citizens have to deal with.
For ecological reasons, climate change affects areas very differently based on geographic location and urban centers represent climate ‘hotspots’ as areas with high vulnerability. As a consequence of this, cities and towns play a crucial role in tackling climate change effects.
The aim of this essay is to analyze the legal aspects of climate change adaptation set by local governments to prevent and manage damages related to climate-related risks. More in detail, after determining the international, European and national legal framework on adaptation, the purpose of the article is to identify the legal instruments used by local administrations to develop adaptation measures. In particular, the analysis focuses on the legal aspects related to three dimensions of local adaptation: urban greening as a nature-based solution for heat waves risks; the management of water-related risks; the civil protection planning function of municipalities. Considering the impacts of the mainstreaming process on planning tools, special attention is directed towards the integration and coordination issue between the different urban and sectoral planning instruments required by the Italian multi-level governance legal system.
Performing an Anti-Homeless City
Authors: Vallejo Toledo Esteban 
Published: November 2021

In the time of globalization, many cities, including the city of Victoria in BC, have engaged in a development model fueled by investment, tourism, and economic immigration. This model requires public authorities to implement policies that contribute to making cities worthy of capital, tourists, and immigrants. Digital connectivity, real estate development, local amenities, and revitalized neighbourhoods are essential ingredients for economic development. In contrast, poverty and urban decay are not good for the way of life that politicians, entrepreneurs, tourists, and urbanites desire. Therefore, all visual manifestations of urban decay, including homelessness, should be restricted by law. In response to this development model, homeless people are forced to perform actions that are banned like building tent cities in parks. In doing so, homeless people challenge exclusionary legal and spatial orderings that support anti-homeless cities.
This paper develops a performativity-based approach to legal geography to contribute to the debate about homelessness in Canada. Rather than focusing on the social right to housing, my argument in this paper zeroes in on the right to use urban space without being excluded. To this goal, I explore interactions between local authorities, homeless people, and other social actors in Victoria to explain that reiterated human interaction is the means to perform and rectify legal and spatial orderings that segregate homeless people. Thus, the performativity-based approach to legal geography developed throughout this paper illustrates not only how anti-homeless cities are socially performed, but also how they are collectively contested.
Transnationalism and Development: The Impact of Remittances to Timor-Leste
Authors:   , Brites Soares Brigida 
Published: November 2021

<p>The aim of this thesis is to Explorer the impact of remittances, sent from Timorese workers in the United Kingdom of Great Britain, Northern Ireland, South Korea and Australia, on the Development of Timor-Leste. The research in this study is from three different perspectives. Firstly, the migration processes and the remittance service providers, which are involved in managing the transfer of remittances from Timorese workers overseas to their families at home. Secondly, the remittance is used by recipient familieson the consumption (durable and non durable goods). Finally, the remittance is used on human capital invest-ment and business investment. From these three perspectives, this thesis examines how remittances con tribute to the development of Timor-Leste. Using a qualitative method, the study addresses one main question: What is the impact of remittances to Timor-Leste? The study was underpinned by qualitative research conducted in Timor-Leste, which has a total popula-tion of 1.1 million. I administered the field research in 7 locations to 30 participants. These included 10 remittance receiving households in the urban district of Dili and 10 from the rural areas of Baucau, Lospa-los, Viqueque, Ainaro, Covalima and Oecusse. Another 10 interviewees were migrant workers domiciled in the United Kingdom of Great Britain and Northern Ireland, South Korea and Australia. The interviews also conducted with relevant Government institutions regarding the process of emigration to work in United Kingdom of Great Britain, Northern Ireland, South Korea and Australia. Also, bank and non-bank institusions as the channel used to transfers remittances from the host countries of the migrants to their families at home. In adopting a combination of theoretical approaches, especially the New Economy of Labour Migration, I argue that remittances have a positive contribution to the development of household participants‟ welfare, the development of human capital and they enable remitters and their families in Timor-Leste to start small and medium businesses. The study also found that the ultimate use of remittances is variously in-vested in productive and unproductive sectors. I further argue that the positive impact of remittances on peoples‟ lives significantly increases the numbers of overseas migrants, which attracts a greater flow of remittances into the country and that urgent government policies are needed to facilitate these more easily.</p>
Cross-Boundary Information Sharing By Knowledge Brokers During A Disaster
Authors:   , Md Ali A Fahimi 
Published: November 2021

<p>This thesis explores and investigates the process of cross-boundary information sharing by knowledge brokers (KB) during a disaster using lenses of knowledge management and naturalistic decision making. The study integrated interpretivist and positivist stances, conducted using qualitative methods. It used a multiple case embedded research design and in-depth face-to-face interviews as the method of inquiry and an inductive process of theory generation. The cases were in the context of disasters that occurred in New Zealand. The unit of analysis was the scenarios that KB experienced during disasters. Based on a four stage analysis of the data, there were two phases that KB went through in assessing the veracity of the information they received and deciding to whom the information is relevant. In each phase, KB were relying on different cognitive resources to filter and to match the information. It was also found that there were different types of boundary, information and disasters. Interestingly, it was found that KB used different tactics to make the decision on the information’s veracity and to whom it is relevant. The primary contribution of this thesis is the generation and explanation of the theoretical model of cross-boundary information sharing by KB during a disaster. This theory can also be used by practitioners as a guide to improve disaster management training and for the community to prepare stronger resilience plans.</p>
‘Tales of Wonder and Horror’: Coverage of insanity in the Leeds press, 1808-1840
Authors:   , Kryssova Evgeniya 
Published: November 2021

<p>The press was at the centre of the reform of the meaning of insanity, during its evolution from an equivocal eighteenth-century concept of melancholia to a medicalised Victorian notion of ‘lunacy’. During the late Georgian era newspapers provided a public forum for the opinion of newly emerging psychiatric practitioners and fostered the fears and concerns about mental illness and its supposed increase. The press was also the main source of news on crime, providing readers with reports on criminal insanity and suicide. In the first half of the nineteenth century, newspaper contents included official legal reports, as well as editorial commentary and excerpts from other publications, and newspaper articles can rarely be traced to one single author. Historians of British insanity avoid consulting periodical literature, choosing to use asylum records and coroners’ reports, as these sources are more straightforward than newspapers. However, Rab Houston’s recent study of the coverage of suicide in the north of Britain shows that the provincial press has been unjustly overlooked and can offer the material for a unique social analysis. Asylum records and coroners’ records do not contain the same detail provided in the press. Newspaper commentary can arguably reveal contemporary attitudes towards insanity and, moreover, sources such as asylum records only deal with the lower-class patients, as the middle- and upper-class insane were usually privately detained. This thesis examines the press coverage of insanity in Leeds newspapers, and expands on previous research by looking at the way insanity was portrayed in the two most popular publications in the industrial region of Yorkshire: the Leeds Intelligencer and the Leeds Mercury. Chapter one focuses on legal cases that featured a verdict of insanity and explores the language used by the press in the reports of, mainly, violent domestic crime. Chapter two looks at reports of suicide and considers how contemporary views on financial and moral despondency influenced the portrayal of self-murder. Chapter three considers editorial articles that cannot be described as either crime or suicide reports. This chapter uncovers the presence of surprisingly humorous and entertaining articles on insanity found in editorials and the ‘Miscellany’ sections of the newspapers. Ultimately, this thesis argues that the reportage of insanity in the Leeds press was sensational, moralistic and selectively sympathetic; furthermore, such portrayal of insanity was reinforced throughout the body of the paper. Leeds newspapers segregated the insane by adopting a moralising tone and by choosing to use class-specific language towards the insane of different social ranks.</p>
Orisa-Shakespeare: A study of Shakespeare Adaptations Inspired by the Yoruba Tradition
Authors:   , Balogun Olalekan Is’haq 
Published: November 2021

<p>This thesis combines creative practice with critical analysis to intervene in the field of post-colonial Shakespeare where, for over a generation, the process of adaptation has been presented as one of the main strategies by which Shakespeare’s ambiguous legacy in successor cultures can be both confronted and manipulated. Scholars often use the term “writing back” to designate a set of adaptations which challenge the cultural capital that Shakespeare privileges. By linking Yoruba spirituality in its political and cultural terms to the wider field of the relation between Africa, African writers and theatre makers and Shakespeare, the thesis proposes a new sub-field or genre of adaptations, “Orisa-Shakespeare,” rooted in Yoruba traditions. The thesis argues that, written in Nigeria and the Yoruba global diaspora, this set of adaptations are not necessarily challenging the Shakespeare canon but addressing their own societies, thus “writing forward.” The thesis examines the cultural and political significance of this bourgeoning body of adaptations of Shakespeare through the lens of Yoruba epistemology and its aesthetic principles. The thesis is broadly divided into two parts: an exegesis of selected adaptations of Shakespeare as case studies of post-colonial works that reflect and integrate Yoruba creative and performative idioms and translate them into dramaturgy; and an original play, Emi Caesar! in which core elements of Shakespeare’s Julius Caesar are transplanted into the complex, violent world of Yoruba politics of the mid-19th century, as a parable for contemporary Nigeria politics where factionalism (specifically tribal/ethnic bigotry) works against the integrity and security of the society. In the context that the thesis proposes, the present has constant recourse to the past, especially the ancestors, and engages in rituals which create ongoing, living links between human beings and the realm of the Yoruba Gods (Orisa).The outcomes are the documentation of a uniquely Yoruba theory of literary creativity, a new play based on Julius Caesar, and an original contribution to the broad field of postcolonial (Shakespeare) adaptations scholarship.</p>
An Exploration of Children’s Connection to Nature: Aotearoa New Zealand
Authors:   , Stuart-Currier Sara Abigail 
Published: November 2021

<p>“People protect what they love” - Jacques Cousteau It’s unavoidable that the next generation will be faced with resolving our current and future environmental issues. It is suggested that children must first care about the environment before they are asked to save it, however, a more indoor childhood is forming a disconnect between child and the natural world. Rooted in the theory that a connection to nature (i.e. our affective and experiential relationship with the natural world) influences a willingness to protect it, this thesis aims to unearth the relationships between connection to nature and environmental attitudes and behaviours of children in Aotearoa New Zealand. To do so this study will: 1) Explore the underlying dimensions of children’s connection to nature, 2) Identify the factors that are related to children’s connection with nature, 3) Investigate the variables that best predict children’s willingness to act for the environment, 4) Investigate the variables that best predict children’s household pro-environmental behaviour. Findings from a quantitative questionnaire suggest that a child’s (n = 450) connection to nature is related to a plethora of variables; most notably exhibiting a strong relationship with their willingness to act for the environment. Furthermore, children’s experiences in nature best predict their household’s pro-environmental behaviour. These findings contribute to past research which suggest that positive relationships with nature, partially formed from time spent in nature, relate to pro-environmental attitudes. This study addresses gaps in Aotearoa New Zealand in regards to children’s connection to nature. It will benefit local policy makers and educators who are dedicated to strengthening the child and nature bond and/or conserving Aotearoa New Zealand’s natural environment.</p>
Tiền là Tiên là Phật: Investigating the persistence of corruption in Vietnam
Authors:   , Vu Anh Dao 
Published: November 2021

<p>This research aims to examine the persistence of corruption in the public sector in Vietnam and explain why anti-corruption measures have been unsuccessful. It seeks to capture people’s lived experience of corruption in Vietnamese society and their perception of the failure of anti-corruption measures. It demonstrates what government officials and ordinary citizens think about corrupt practices and how they explain corrupt behaviour. The research also draws a clearer picture of Vietnam’s anti-corruption system, the weaknesses of the Anti-Corruption Law (ACL) and its implementation, from insiders’ perspectives. The research illuminates some factors identified in the literature that need to be better understood when dealing with corruption: historical, cultural, economic, administrative and political factors. This project situated Vietnam’s anti-corruption strategy within Jon Quah’s analytical framework, which identifies elements he argues are needed for an effective anti-corruption strategy in any country. Those elements include a set of formal, legal, and institutional instruments, and the need for political will, especially from governmental leaders. A qualitative approach is applied to examine corruption in the public sector in Vietnam. The main data was gathered by in-depth, semi-structured interviews and from official documents. Different groups of participants - specialists in the anti-corruption field including politicians, high-ranking government officials, journalists, academics, international organisations, and NGOs - were interviewed. Vietnamese citizens also were interviewed; all had experienced corruption in their daily life. The findings suggest an institutional anti-corruption framework, while necessary, cannot adequately deal with the multi-factor causes of corruption in Vietnam. Moreover, “political will” is not only about providing Anti-Corruption Agencies with enough resources, nor about their institutional arrangements, but also about politicians being willing to support the institutions they have created and to reinforce their effectiveness by making hard political decisions. The essential elements of political will in fighting corruption involve not only the institutional framework (the top-down approach) but also society as a whole (the bottom-up approach). The thesis concludes that corruption in the public sector in Vietnam is the product of a complex mix of state institutions, elite political behaviour, social, cultural, economic and management factors. These are at the root of the corruption problem in the country, but they have not been seriously addressed. The current anti-corruption system needs to be reformed if it is to become more effective. Policy attention also needs to shift to the design of effective incentives for the populace to resist succumbing to bribe demands. This “citizen resistance” will, in fact, make governments more accountable for taking effective action against both grand and petty corruption.</p>