bluuebunny/crossref_metadata_2025_split huggingface dataset:
Trajectories of antidepressant use and 6-year change in body weight: a prospective population-based cohort study
Authors: Lassale Camille , Lugon Gabriela , Hernáez Álvaro , Frank Philipp , Marrugat Jaume , Ramos Rafael , Garre-Olmo Josep , Elosua Roberto 
Published: December 2024

BackgroundAntidepressant drug treatment may be associated with weight gain, but long-term studies are lacking.MethodsWe included 3,127 adults (1,701 women) from the REGICOR study, aged 55.6 (SD = 11.6) years on average in 2003–2006, living in the northeast of Spain. They had data at two time points (baseline and a median of 6.3 years later) on self-reported antidepressant use, body weight and height, and on baseline smoking, physical activity, diet quality, education, civil status, and depressive symptoms assessed with the Patient Health Questionnaire (PHQ-9) at follow-up. We defined four trajectories of antidepressant use as follows: never use, new use at follow-up, initial use discontinued, repeated use at both time points. We used multivariable linear models to estimate the association of these trajectories with the percentage of weight change. In people without obesity at baseline (n = 2,404), we also estimated the association with obesity incidence at follow-up.ResultsThe average 6-year weight gain was 0.53 kg (1.01% body weight), and 24.5% of the participants gained &gt;5% of body weight. The majority (83.6%) of participants did not report any use of antidepressants, 6.2% initiated during follow-up, 5.1% discontinued it, and 5.1% reported their use at both time points. In multivariable analyses, compared to never users, all trajectories were associated with greater weight gain: +1.78% (0.57, 2.98) for initial use discontinued, +2.08% (0.97, 3.19) for new use at follow-up, and +1.98% (95% CI: 0.75, 3.20) for repeated use. In non-obese participants at baseline (n = 2,404), the odds ratio for becoming obese was 2.06 (1.03, 3.96) for repeated use and non-statistically significant for the other trajectories.ConclusionsIn a population-based adult cohort, repeated use of antidepressants was strongly associated with weight gain. New and discontinued use was associated with weight gain, but non-significantly to obesity incidence. Given the global obesity epidemic and the widespread use of antidepressants, weight management and metabolic monitoring should be encouraged and integrated into depression follow-up guidelines alongside antidepressant prescriptions.
Acupuncture treatment of restless legs syndrome: a randomized clinical controlled study protocol based on PET-CT and fMRI
Authors: Tang Lin , Zhao Na , Gao Xiaolin , Li Jinjin , Yu Xintong , Liang Ruilong , Xie Chen , Li Lutong , Wang Qianqian , Yang Wenjia 
Published: December 2024

IntroductionRestless legs syndrome (RLS) is a sensorimotor disorder of the nervous system that is mainly characterized by nighttime leg discomfort and can be accompanied by significant anxiety, depression, and other mood disorders. RLS seriously affects the quality of life. Clinical studies have confirmed that acupuncture can alleviate the clinical symptoms of RLS. This randomized controlled trial (RCT) aims to investigate the efficacy of acupuncture in the treatment of RLS and further explore the central response mechanism of acupuncture in the treatment of RLS.Methods and analysisIn this RCT, a total of 124 eligible patients in Shanghai will be randomly assigned to one of the following two groups: treatment group (acupuncture) and control group (sham acupuncture). Treatment will be given three times per week for 4 consecutive weeks. The primary outcome is the International Restless Legs severity rating scale (IRLSS). The secondary outcomes are the RLS-Quality of Life (RLSQoL), the Insomnia Severity Index (ISI), Pittsburgh Sleep Quality Index (PSQI), the Hamilton Depression Scale (HAMD), and the Hamilton Anxiety Scale (HAMA). The objective evaluation tools will be polysomnography, positron emission tomography–computed tomography (PET-CT), and functional magnetic resonance imaging (fMRI) of the brain. All adverse effects will be assessed by the Treatment Emergent Symptom Scale. Outcomes will be evaluated at baseline (1 week before the first intervention), during the intervention (the second week of the intervention), after the intervention (at the end of the intervention), at 1-month follow-up, and at 3-month follow-up.Ethics and disseminationThe trial has been approved by the Ethics Committee of Yueyang Hospital of Integrated Traditional Chinese and Western Medicine (no. 2022-061). Written informed consent will be obtained from all participants. The results of this study will be published in peer-reviewed journals or presented at academic conferences.Clinical trial registrationhttps://www.chictr.org.cn/, identifier ChiCTR2000037287.
Countertransference, alliance, and outcome in the treatment of patients with personality disorder: a longitudinal naturalistic study
Authors: Breivik Øvstebø Randi , Pedersen Geir , Wilberg Theresa , Røssberg Jan Ivar , Johnsen Dahl Hanne-Sofie , Kvarstein Elfrida Hartveit 
Published: December 2024

ObjectiveRelational dynamics, including countertransference responses and the therapeutic alliance, are crucial in the treatment of patients with personality disorders (PD). However, few studies on PD treatment focus on the dyadic process of therapy. The present study aims to investigate associations between therapist emotional response/countertransference (CT) and patients’ experience of treatment alliance, and CT developments in therapies with treatment completion as outcome.MethodA longitudinal, observational study of patients (N = 365) treated at PD treatment units within specialist mental health services. CT was assessed repeatedly during therapy by the Feeling Word Checklist – Brief Version with three subscales—Inadequate, Confident, and Idealized. Early alliance was assessed after 6 months of treatment (Working Alliance Inventory, WAI). Treatment completion was defined as completing treatment according to schedule versus not completing treatment. Statistical analyses included Linear Mixed Models.ResultsIn the early phase of therapy, lower WAI predicted lower levels of Confident, Idealized, and higher Inadequate CT. The relation between early WAI and CT levels during treatment remained stable. The development of CT during treatment differed according to treatment completion with significant trends of increasing Inadequate CT and decreasing Idealized CT in not completed treatments. WAI and treatment completion had strong and independent effects. Further moderator analysis did not yield additional information.ConclusionThe study demonstrates significant associations between negative CTs and lower patient-rated WAI in the early phase of therapy, and a development of increasingly more negative CTs during therapy in treatments which were not completed according to schedule. The results indicate high clinical relevance of monitoring therapeutic relationships in PD treatments. Further research on the emotional and relational quality of psychotherapeutic relationships in PD treatments is needed.
Moderating effects of demographic characteristics on the relationship between parenting practices and energy balance related behaviors of Chinese preschoolers
Authors: Peng Zhou , Lau Patrick Wing-chung , Wen Li Ming 
Published: December 2024

BackgroundEarly establishment of energy balance related behaviors (EBRBs) may be effective in combating unhealthy lifestyle in preschoolers. Parents are responsible for cultivating preschoolers’ EBRBs directly through parenting practices. Although investigating the impact of various parenting practices on preschoolers’ EBRBs is crucial to determine which practices should be recommended to parents to help reverse childhood unhealthy lifestyle, it is important to assess whether these effects of parenting practices on preschoolers’ EBRBs would be similar across different groups of preschoolers, necessitating research into the moderating effects of demographic characteristics.MethodsBaseline dataset was utilized from an electronic health intervention study of Chinese 3-6-year-old preschoolers. Preschoolers’ PA and sleep duration and quality were objectively examined using wGT3X ActiGraph accelerometer. Data related to parents and preschoolers’ eating behaviors and sleep problems were subjectively assessed using parent-reported questionnaires. The PROCESS macro version 4.2 was used to perform moderation analysis. When the interaction revealed a p-value of less than 0.05 and the 95% confidence interval did not include 0, the conditional effects of the focal predictor at various levels of the moderator were further examined (p &lt; 0.05) to investigate how the relationship between parenting practices and preschoolers’ EBRBs varied with different moderator levels.ResultsMarried parents exhibited the desired outcomes in the relationship between parenting practices and their preschoolers’ EBRBs. In contrast, divorced/separated parents showed unfavorable results in this relationship. The association between the parents’ and preschoolers’ BMI varied depending on parents’ socioeconomic status, the preschoolers’ age, and the number of children in the household. The preschoolers’ age showed different moderating trend on the relationship between parents’ PA and preschoolers’ sedentary behaviors as well as the association of eating-related PSE with preschoolers’ eating behaviors. The mechanisms linking the parents’ PSE to the preschoolers’ PA, sedentary behaviors, and sleep duration were influenced by the preschoolers’ gender and the number of children in the household.ConclusionThe potential parental influence warrants further investigation with the consideration that the relationship between parenting practices and preschoolers’ EBRBs varied across different group of children.Clinical trial registrationNCT06025019.
Healthcare provider perspectives on barriers and facilitators to integration of cardiovascular disease-related care into HIV care and treatment clinics in urban Tanzania
Authors: Ottaru Theresia A. , Ngakongwa Fileuka C. , Butt Zeeshan , Hawkins Claudia A. , Kaaya Sylvia F. , Metta Emmy O. , Chillo Pilly , Siril Helen N. , Hirschhorn Lisa R. , Kwesigabo Gideon P. 
Published: December 2024

BackgroundThe increase in the dual burden of HIV and cardiovascular diseases (CVD), calls for the provision of integrated HIV/CVD care. This study aimed to explore barriers and facilitators to the integration of HIV/CVD care within HIV care and treatment clinics (CTCs) in urban, Tanzania.MethodsBetween March and April 2023, we conducted 12 key informant interviews with healthcare providers at six HIV CTCs in urban, Tanzania. Guided by the Consolidated Framework for Implementation Research (CFIR 1.0), we designed the interview guide and conducted a thematic analysis.ResultsOut of the 11 CFIR constructs explored, three were barriers (cost, availability of resources, and access to information and knowledge), six were facilitators (complexity, relative advantage, patient needs, external policies and incentives, relative priority, and knowledge and belief about the intervention), and two (compatibility and self-efficacy) were both barriers and facilitators. Barriers to integration included a lack of equipment, such as BP machines, lack of space, unavailability of an electronic data-capturing tool at the HIV CTCs for monitoring CVD outcomes, and a shortage of trained healthcare workers, particularly in managing CVD comorbidities according to current recommendations. Providers acknowledged the increasing demand for CVD care among ALHIV and regarded integration as not a complex task. Providers reported that both services could be delivered simultaneously without disrupting client workflow and were determined to offer integrated care within HIV CTCs. Providers expressed concerns about medication costs and recommended that medications should be provided for free as part of the integrated care.ConclusionEffective and sustainable HIV/CVD integrated care requires an understating of the existing barriers and facilitators within the HIV CTCs. This study identifies key barriers at HIV CTCs that must be addressed and facilitators to be leveraged before CVD care is integrated into HIV CTCs to ensure that CVD care is delivered effectively within an integrated system.
Organic food consumption in Kenitra, Morocco: attitudes, motivations, and barriers
Authors: Lafram Amina , Belfakira Chaimaa , Hindi Zakia , Bikri Samir , Benayad Asmaa , El Bilali Hamid , Bügel Susanne Gjedsted , Średnicka-Tober Dominika , Pugliese Patrizia , Strassner Carola , Rossi Laura , Stefa-novic Lilliana , Aboussaleh Youssef 
Published: December 2024

IntroductionMorocco is currently witnessing a growing interest in organic food as awareness of health and environmental benefits rises.ObjectiveThis study aims to evaluate organic food consumption as well as to understand the underlying factors influencing the consumption patterns, including consumers’ preferences and motivations as well as the challenges they face in Kenitra (Morocco).MethodData was collected through an anonymous household survey involving 442 respondents, aged 18 and above targeting the population of Kenitra.ResultsThe findings reveal that in 60% of the Kenitra households organic foods comprise 1-25% of all the foods consumed, highlighting a growing interest in these products. However, several barriers were identified, including insufficient availability and accessibility of organic products, as well as limited product variety at local shopping places, and the perceived high prices of organic foods, which continue to hinder organic food consumption. Moreover, consumers expressed a need for better access to organic products and emphasized the importance of reasonable pricing, considering it as a significant factor in their decision-making process.ConclusionUnderstanding the dynamics of organic food consumption in Kenitra and the eating attitudes and behaviors of its residents will provide valuable insights that can be employed to reshape future local policies, strategies, and market developments, in response to the changing demands and preferences of the population while promoting the adoption of organic food in the region and the whole country.
The Effect of Ankle Dorsiflexion on Sagittal Posture and Core Muscle Activation
Authors: Reis e Silva Miguel , Lerebourg Lucie 
Published: December 2024

Maintaining proper posture is essential for preventing musculoskeletal disorders and reducing injury risks. This study investigates the impact of insoles with ankle dorsiflexion (inverted drop sole) on sagittal posture, spinal curvatures, and core muscle activation. Methods: Fifty-five participants (29 men, 26 women; aged 20–70 years) were evaluated in two conditions: barefoot and with insoles incorporating an inverted drop sole. Kinematic data of trunk, hip, and knee angles, along with spinal curvatures (dorsal kyphosis, lumbar lordosis, and sacral slope), were collected using the Simi Aktysis 3D system and the Medi Mouse IDIAG 360®. The electromyographic (EMG) activity of the rectus abdominis and rectus femoris muscles was analyzed using the Bioplux® device. Statistical analyses were conducted using Wilcoxon tests (W) for non-parametric data and Student’s t-tests (T) for parametric data with significance set at p < 0.05. For parametric data, effect size (ES) was used to assess the magnitude of differences based on the Cohen scale. For nonparametric data, the rank biserial correlation (rB) was used, considered an ES equivalent to the correlation coefficient. Results: Significant differences were observed between the barefoot and insole conditions for trunk and knee angles (p = 0.009 and p < 0.001, respectively) with moderate and large magnitude of difference (rB = −0.41 and rB = −0.96, respectively). No significant change in hip angle (p = 0.162) was observed. Spinal curvatures, including dorsal kyphosis, lumbar lordosis, and sacral slope, significantly decreased (p < 0.001), with a large magnitude of difference for dorsal kyphosis, lumbar lordosis, and sacral scope (rB = 0.71, rB = −0.94 and ES = 0.54, respectively). EMG analysis revealed the increased activation of the rectus abdominis and rectus femoris muscles (p < 0.001), with a large magnitude of difference both the rectus abdominis and rectus femoris (rB = −0.82, and ES = −0.82, respectively). Conclusions: Insoles with ankle dorsiflexion significantly improve sagittal posture by reducing spinal curvatures and enhancing core muscle activation. These findings suggest that dorsiflexion technology in footwear may serve as a non-invasive strategy for improving posture, preventing musculoskeletal disorders, and managing low back pain.
Analysis of Acoustic Surface Wave Focused Unidirectional Interdigital Transducers Using Coupling-of-Mode Theory
Authors: Hui Guopeng , Ao Tinglun , Liu Haotian , Li Minglei , Chen Chen 
Published: December 2024

In cell or droplet separation, high acoustic wave energy of a surface acoustic wave (SAW) device is required to generate sufficient acoustic radiation force. In this paper, the electrode width-control floating electrode focused unidirectional interdigital transducer (EWC-FEFUDT) is proposed due to its enhanced focusing properties. The performance of the EWC-FEFUDT is investigated using the Coupling-of-Mode (COM) theory, and the COM parameter is extracted using the Finite Element Method (FEM). The four different forbidden band edge frequencies account for the unidirectionality of the proposed EWC-FEFUDT. A direction angle of ϕκ−ϕζ=44.5° of the EWC-FEFUDT (Design 3) is obtained, being fairly close to the optimum value of 45°. The EWC-FEFUDT (Design 3) has a lower insertion loss (IL) of −5.1 dB and greater unidirectionality (20 × log10(D) = 13.8 dB). The SAW maximum amplitude of the EWC-FEFUDT (Design 3) is increased by about 1.5×10−4 µm compared to that of the focused interdigital transducers (FIDTs). The maximum acoustic pressure of the EWC-FEFUDT is an order of magnitude higher than that of FIDTs. The EWC-FEFUDT exhibits enhanced focusing properties. The proposed EWC-FEFUDT may provide an alternative method for cell or droplet separation in an efficient manner.
Автоматизація вимірювань швидкості хімічного травлення тонких плівок
Authors: Іваницький В. П. , Рубіш В. М. , Тарнай А. А. , Чичура І. І. , Рубіш В. В. , Далекорей А. В. , Мешко Р. О. , Рябощук М. М. , Цигика В. В. 
Published: December 2024

Проаналізовано особливості застосування інтерференційного методу для контролю товщини тонких плівок і вимірювань їхньої швидкості травлення. Розроблено оптичну структурну схему інтерференційного методу, яка є оптимальною для автоматичного вимірювання швид-кості травлення тонких плівок. Як елементи всього оптичного тракту схеми рекомендовано застосовувати оптичні волокна. Експеримен-тально досліджено закономірності змін інтерференційної картини на тонких плівках As2S3 під час їхнього хімічного травлення у водному розчині карбонату натрію. Проведено оцінку абсолютної похибки автоматичних вимірювань швидкості травлення, яка не перевищує ± 0,5 нм/с. Показано, що запропоновані підходи придатні для проектування пристроїв автоматичного контролю процесів хімічного травлення різних речовин.
Strategi Pengembangan Karir di Sektor Jasa Keuangan: Studi Literatur di Era Digital
Authors: Bani Pristiwanto 
Published: December 2024

Tujuan dari penelitian ini adalah untuk menjelaskan strategi pengembangan karir pada sektor jasa keuangan di era digital yang dapat digunakan untuk menghadapi tantangan dalam mengembangkan berbagai program peningkatan kapasitas dan kompetensi. Metode penelitian dalam penelitian ini menggunakan tinjauan pustaka yang sistematis. Data penelitian ini diperoleh melalui beberapa artikel, jurnal nasional dan internasional bereputasi dengan kata kunci pengembangan karir dan sumber daya manusia di era digital khususnya sektor jasa keuangan. Analisis data dalam penelitian ini menggunakan analisis data kualitatif. Hasil penelitian menunjukkan bahwa terdapat beberapa tantangan yang dihadapi dalam mengembangkan karir pada sektor jasa keuangan di era digital, antara lain: kemampuan dalam penguasaan teknologi informasi, kepatuhan terhadap standar etika dan regulasi yang berpusat pada pelanggan, kemampuan dalam hal mengeksplorasi keterkaitan antara teknologi yang sedang berkembang, seperti Fintech, AI, blockchain dan digitalisasi, serta meningkatnya kebutuhan akan keterampilan baru, pertimbangan etis, dan kepemimpinan inovatif. Selain hal tersebut semakin pentingnya soft skill seperti kemampuan beradaptasi, pembelajaran berkelanjutan, dan kolaborasi lintas fungsi bersamaan dengan kemahiran teknis. Selain itu, penelitian ini mengidentifikasi tantangan dalam mengembangkan kemampuan ini, termasuk pesatnya perubahan teknologi, kompleksitas peraturan, dan perlunya transformasi budaya dalam lembaga keuangan. Penelitian ini berkontribusi pada pengetahuan yang ada dengan memberikan gambaran komprehensif tentang kemampuan digital yang diperlukan di sektor jasa keuangan. Studi ini memberikan wawasan berharga bagi lembaga keuangan, lembaga pendidikan, dan pembuat kebijakan dalam mengembangkan strategi untuk mengatasi kesenjangan keterampilan digital di industry sektor jasa keuangan.
Analysis of Planned Flood Discharge in the Grompol Watershed
Authors: Wulandari Aprilia Indah , Mulyandari Erni , Yuono Teguh 
Published: December 2024

The Grompol watershed is one of the sub-watersheds of Bengawan Solo located in Karanganyar Regency and Sragen Regency. When the intensity of rainfall is high, the area downstream of the Grompol River often floods to cause many losses. Therefore, analyzing the planned flood discharge as a reference in flood control efforts is necessary. This study aims to identify the most common problems in the Grompol River flow, identify flood points in the Grompol River and its countermeasures, analyze the size of the Grompol Watershed using QGIS 3.10.6 Software, and calculate the amount of planned flood discharge in the Grompol Watershed. The method in this study is the Nakayasu Synthesis Unit Hydrograph Method, with a repeat period of 25 years. The analysis stage begins with conducting a location survey and interviews and then conducting a planned flood discharge analysis. Based on the results of the research, it was found that the problems that occur a lot in the Grompol River flow are sediment, organic waste, and inorganic waste, as well as streams that have been flooded at 4 points out of 31 survey locations, namely in the settlements around the Gedangan Lor Bridge, Gading Grompol, Gantung Kedusan, and Pringanom, where flood control efforts are dominated in the form of community service, an area of the Grompol watershed is obtained using Software QGIS 3.10.6 is 164,95 km2 while for flood discharge for the 25-year recurrence period using the Nakayasu Synthetic Unit Hydrograph Method of 623,32 m3/s.