bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of preoperative feeding with germinated brown rice supplement on clinical outcome of orthopaedic and gastrointestinal surgery patients
Authors: Thacker Pooja , Mandalika Subhadra , Shah Rahul , Doctor Nilesh 
Published: July 2021

Background: Malnutrition prior to surgery can lead to inflammation, increased length of hospital stay, bed sores, muscle weakness, poor quality of life and mortality post-surgery in patients. Therefore, preoperative drinks that have been enriched with vitamins, easily digestible carbohydrates and amino acids have been necessitated by ESPEN. Health benefits of brown rice, which is a good source of phytonutrients like GABA, Ferulic acid Oryzanol and B- complex, BCAA and maltodextrin, have been well researched.Methods: In the present study, a nutritious product was developed using germinated brown rice, salt and micronutrient mix (GBR Mix), analysed quantitatively (Proximate composition) and qualitatively (Phytochemicals). Major orthopaedic and gastrointestinal surgical patients in the age group of 40-65 years (n=124) were supplemented with GBR Mix in bouts of 3 meals (20gms x 3meals) namely lunch, mid-evening and bedtime time snack, 8 hrs prior to surgery unlike other patients who fasted for 12-16 hours prior to surgery. They were assessed for nutritional status, Serum Albumin, inflammatory markers (CRP and WBC), post-surgery complications and length of hospital stay.Results: Supplementation was found to improve blood sugar (p<0.05) in gastroenterology patients, reduce inflammatory markers like CRP(p=0.053) and WBC (p<0.001), reduced nausea and vomiting, improved food and fluid intake post-surgery in the patients. Additionally, length of hospital stay was also reduced (p=0.001).Conclusion: Thus, germinated brown rice could be recommended as an economical nutritious and anti-inflammatory pre surgery feed.Keywords: GBR, LOS, MUST, SGA, CRP, Micronutrient Mix
Health risk assessment of rural older population
Authors: Ge Minshu , Zhu Dan , Lee Hallie 
Published: July 2021

BACKGROUND: With the accelerated development of aging, the health problems of rural elderly are becoming increasingly severe. OBJECTIVE: The study aims to understand the mental health issues of the rural older population. METHODS: The risk factor analysis and the disease risk assessment are utilized to analyze the impacts of depression on older adults. First, the prevalence of depression in China’s rural older population is counted and analyzed. Next, both single and multi-factor analyses are employed to analyze the degree of depression among rural older adults quantitatively, and the existing risk factors are determined. The multiple risk factors and multi-source logistic regression algorithm establish the risk assessment model of depression in the rural older population. Finally, the risk factors of depression in older adults are calculated by analyzing and processing the above statistical data. A risk assessment model of depression is built, whose sensitivity and specificity are tested. RESULTS: Single-factor analysis and multi-factor analysis reveal 20 vital influencing factors of depression in older adults, such as cognitive ability, emotional state, and memory. The sensitivity and specificity of the risk assessment model based on multi-factor logistic regression are 87.3%80.2%, respectively, capable of effectively assessing and screening the potential population of depression among older adults. CONCLUSIONS: This model provides a scientific basis for screening out and preventing older adults’ mental health issues with depression and improving older adults’ quality of life.
ВНЕСОК ЖІНОК-МОРФОЛОГІВ В РОЗВИТОК КИЇВСЬКОЇ АНАТОМІЧНОЇ ШКОЛИ (ДО 180-РІЧЧЯ НАЦІОНАЛЬНОГО МЕДИЧНОГО УНІВЕРСИТЕТУ ІМЕНІ О.О. БОГОМОЛЬЦЯ)
Authors: Prysyazhnyuk Larisa , Yanchishin Andrey , Dzevulska Irina , Sinitskaya Alla , Matkivskaya Ruzhena , Ostapyuk Lyubov , Kovalchuk Oleksandr 
Published: July 2021

Історичний розвиток науки неможливий без урахування зв’язків з усім попереднім досвідом людства. Всі медичні науки, в тому числі і анатомія, мають свою історію, тобто весь пройдений шлях розвитку і вдосконалення. Велике значення в розвиток як вітчизняної анатомічної науки, так і Київської анатомічної школи, внесли жінки-науковці. Окрім цього і дотепер вони продовжують виконувати важливу роль в різних напрямках роботи кафедри і Університету. Метою роботи є висвітлити внесок жінок-морфологів Київської анатомічної школи на головних етапах розвитку українських досліджень, прослідкувати тенденції і напрямки їх роботи. Нами було використано проблемно-орієнтований аналіз історичних інформаційних джерел, архівні матеріалів кафедри описової та клінічної анатомії НМУ імені О.О. Богомольця. В довоєнні та післявоєнні роки науковий пошук співробітників кафедри був спрямований в основному на вивчення лімфатичної системи. В подальшому кафедра анатомії людини займалася вивченням гемо-, лімфо- і мікроциркуляторного русла функціонально різних органів. І за цей період жінками кафедри були захищені ряд кандидатських та докторських дисертацій. В останні роки науковий пошук на кафедрі анатомії людини був спрямований на вивчення морфологічних змін в органах при опіковій хворобі та дії різних чинників зовнішнього середовища в організмі. І в цьому напрямку жінки кафедри досить плідно працюють. Жінки-анатоми беруть активну участь в організації і проведенні багатьох сучасних наукових досліджень, в наукових конференціях, симпозіумах, з’їздах, є співавторами кількох патентів і авторських свідоцтв, монографій, навчальних посібників, зробили значний внесок в навчально-методичну роботу, були співавторами методичних рекомендацій для викладачів та студентів. Жінки кафедри проходили закордонне стажування, вели активну громадську роботу. Науково-педагогічна робота жінок кафедри за вагомий внесок в розвиток сфери охорони здоров’я, багаторічну сумлінну працю та високий професіоналізм, була відмічена урядовими нагородами, почесними грамотами Університету і Міністерства охорони здоров’я України. Сумлінною працею і наполегливістю у ставленні до своєї справи були переповнені життєві шляхи трудолюбивих, цілеспрямованих жінок Київської анатомічної школи. Їх педагогічні заслуги, щирі намагання дати глибокі знання своїм учням ставали прикладом для наступних поколінь.
ПОЛІМОРФІЗМ G20210A ГЕНА F2 ТА ЙОГО ЗВ'ЯЗОК З АКТИВНІСТЮ ПЛАЗМОВОГО ГЕМОСТАЗУ У ПАЦІЄНТІВ З ГОСТРИМИ КОРОНАРНИМИ СИНДРОМАМИ, АСОЦІЙОВАНИМИ З ЦУКРОВИМ ДІАБЕТОМ 2 ТИПУ
Authors: Karpenko Olena 
Published: July 2021

Складні захворювання, такі як ішемічна хвороба серця та цукровий діабет, спричинені нелінійною взаємодією численних генетичних та екологічних факторів ризику. Характеристика не тільки генів-кандидатів, а й складних взаємодій між ними є, очевидно, більш потужним підходом до вивчення таких захворювань. Невідповідність даних різних досліджень пояснюється тим, що генетичний ризик ішемічної хвороби серця базується не на дії окремого гена, а на взаємодії між декількома патофізіологічними шляхами, контрольованими кількома генами, та іншими факторами ризику. Метою дослідження стало визначення стану активності згортання крові у пацієнтів з ізольованим та коморбідним перебігом гострого коронарного синдрому та цукрового діабету 2 типу залежно від поліморфізму G20210A гена F2. Матеріали та методи: В процесі дослідження нами було обстежено 60 хворих, які проходили лікування у відділенні невідкладної кардіології: 30 хворих на гострий коронарний синдром, 30 хворих на гострий коронарний синдром та цукровий діабет та 15 осіб, що склали групу контролю. Для молекулярно-генетичного аналізу використовували зразки ДНК пацієнтів, виділені з венозної крові сорбентним методом. Поліморфізм G20210A гена F2 визначали методом полімеразної ланцюгової реакції з використанням двопраймерної системи та готових реагентів («Синтол», Росія) на апараті Applied Biosystems 7500. Статистична обробка результатів здійснювалася за допомогою програми SPSS-23. Результати: Проаналізувавши дані, можемо вказати на відсутність зв’язку між мутацією гена F2 та активацією процесів згортання у групі хворих на гострий коронарний синдром. Висновки: Таким чином, у групі пацієнтів з гострим коронарним синдромом не виявлено значущої залежності між показниками згортання крові, антикоагуляційною системою крові та поліморфізмами G20210A.
ISTIKHDAMU LU’BAH BERBURU HARTA KARUN LI TARQIYATI ISTI’AB AL MUFRADAT LADAYYA THULABAH BI SMA N 4 LANGSA
Authors: Wahyuni Sri , M.Fadli  
Published: July 2021

Pembelajaran mufradat memiliki hubungan yang kuat dengan pembelajaran maharah kebahasaan yang hadir dalam pembelajaran bahasa arab dari segi memahami judul dan tujuannya sama seperti bahasa penghubung, sama-sama memiliki tujuan yang penting dari segi pembelajaran. Dan tujuan penelitian ini untuk mengetahui penggunaan permainan berburu harta karun pada pembelajaran mufradat dan untuk mengetahui efektivitas penggunaan permainan berburu harta karun pada pembelajaran mufradat dalam meningkatkan kemampuan siswa.Dan populasi pada penelitian ini seluruh siswa kelas sepuluh yang ada di SMA N 4 Langsa tahun ajaran 2019/2020 dengan jumlah siswa 96 siswa, dan sampel kelas XIPS1 sebagai kelas eksperimen dan XIPS2 sebagai kelas kontrol . Dan penelitian ini menggunakan pendekatan kuantitatif dengan metode eksperimen. Dan peneliti ini menggunakan observasi, wawancara, dan tes untuk mengumpulkan data dan informasi. Sesudah peneliti melakukan penelitian maka hasil penelitian ini adalah penggunaan permainan berburu harta karun pada pembelajaran mufradat sesuai dengan teori dan penggunaan permainan berburu harta karun efektif pada pembelajaran mufradat dalam meningkatkan penguasaan kosakata siswa dengan bukti thitung lebih besar dari ttabel dengan nilai 7,28>2,000 maka hipotesis di terima.
Encoded Weakening of the European Integration – The EU-specific Vectors of Disorientegration
Authors: Kovács Olivér 
Published: July 2021

The paper attempts to contribute to the better understanding of how the centrifugal force towards weakening European integration has developed by identifying the EU-specific vectors of such gradient. We argue that disorientegration is an echo effect of a complex amalgam of mutually intertwined and interrelated mechanisms embedded secularly into our European integration process. The paper also addresses whether secular stagnation adds to that centrifugal force. The paper finally outlines at least six potential principles of reversing the European disorientegration by cultivating contingency governance.
The Relationship Between Increased Debt Ratio and Economic Growth in the European Union: The Granger Causality Approach
Authors: Marton Ádám 
Published: July 2021

Increased government debt rates in recent years can be easily financed in the current global economic environment characterised by liquidity abundance. Nevertheless, the debt ratios represent a potential threat under the surface, which could lead to significant macroeconomic problems in the future. The purpose of the paper is to contribute to the debate in the empirical studies between public debt and economic growth, as well as external debt and economic growth. During the analyses, the relationship between variables was examined using the panel Granger causality test with the Dumitrescu–Hurlin test in the Member States of the European Union. The main findings of the study are that there is a unidirectional causal effect between public debt and economic growth, that is, only debt impacts on the economic growth. In case of external debt and economic growth there is also a unidirectional effect, but it is in the reverse direction. In addition, the pre-crisis and post-crisis period was also examined, on the basis of which it can be concluded that before the crisis, the nature of the relationship was bidirectional between public debt and economic growth, whereas after the crisis the debt had an impact on the economy growth, and the reverse effect does not exist.
The Role of Transport in Catching Up of New Member States
Authors: Szilágyi Balázs 
Published: July 2021

New members joined the European Union in 2004 in the hope of catching up. One of the fields where new members are lagging is transport. After joining the EU, investments in transport infrastructure and transport equipment have risen remarkably, mainly due to EU funding. At the same time, GDP growth of new members has exceeded the EU average. This paper examines the connection between investment in transport and economic growth in the European Union focusing on the group of its Central and Eastern European new members. Direct effects of investments, indirect effects on productivity and welfare, as well as crowding in effects on further investments are considered. This paper aims to identify issues for further research and to give an outlook for the decade of the 2020s.
A magyarországi bankfiókhálózat területi elhelyezkedésének és klasztereződésének vizsgálata az európai bankfiókbezárási trend közepette 2020-ban
Authors: El-Meouch Nedim Márton , Alpek B. Levente 
Published: July 2021

Az Európai Unió egészében a bankfiókok számának jelentős csökkenését tapasztaltuk az elmúlt években, amellyel összefüggésben felmerül a bankfiókok magyarországi területi rendelkezésre állásának kérdésköre. A tanulmány globális és lokális Moran’s I statisztikákkal, valamint Getis–Ord féle G* hotspot elemzéssel a magyar bankfiókok elhelyezkedésének területi autokorrelációját és klasztereződését vizsgálja. Az eredmények alapján a bankfiókok száma Magyarországon települési szinten területileg pozitívan autokorrelált a 2020. januári állapot szerint. A települések bankfiókszámot tekintve klaszterekbe rendeződnek, ahol Budapest és vonzáskörzete egy jelentősebb csomópontnak számít, amelyhez hasonló az országban máshol nem található. Kiterjedtebb cold spotokat a Nyugat- és Dél-Dunántúl régió, valamint Észak- Magyarország és Szabolcs-Szatmár-Bereg megye országhatár menti térségeiben azonosítottunk elsősorban.
Orcein and DAPI-stained karyotype analysis of Alocasia macrorrhizos (L.) G. Don
Authors: Warasy Ashma Ahmed 
Published: July 2021

Karyotype analyses are required for the identification, characterization, and genetic improvement of any organism. Alocasia macrorrhizos (L.) G. Don. was investigated cytogenetically to determine the karyotypic features. Complex chromocenter type, of interphase nuclei, and gradient type of prophase chromosomes were found in this study. Alocasia macrorrhizos was found to possesses 2n=28 chromosomes. The total length of the 2n chromosome complement was recorded as 98.83±1.39 μm. The range of chromosomal length was 2.50±0.10-4.70±0.10 μm. A gradual decrease in chromosomal length was observed. The total form (TF%) value was found to be 43.58%, Karyotype symmetry index (Syi %) was 77.00 % and karyotype asymmetry index (AsK %) was 56.66%. The centromeric formula was 18m+4sm+2ac, representing asymmetric karyotype. In DAPI banding, the 1.48% positive banded region indicates the lower amount of AT rich repeats in this material. Therefore, Alocasia macrorrhizos could be authentically characterized through karyotype analysis.
J. Bangladesh Acad. Sci. 45(1); 27-35: June 2021
Measurement of natural radioactivity and its health hazards associated with the use of different branded cement samples collected from different manufactures in Dhaka city using gamma spectrometry
Authors: Pervin Shikha , Dewan Md Jafor , Apon Ashif Mahamud , Siraz MM Mahfuz , Yeasmin Selina 
Published: July 2021

The radioactivity of naturally occurring radionuclides 226Ra, 232Th, and 40K was determined in thirteen cement samples collected from different manufactures of Dhaka city. The measurement was performed by gammaray spectrometry system using high purity germanium (HPGe) detector. The average activity of 226Ra, 232Th, and 40K in cement samples are fon und to be 30.23±15.04 Bqkg-1, 20.10±11.76 Bqkg-1 and 145.27±24.14 Bqkg-1, respectively. The average values of radium equivalent activity (Raeq), absorbed dose rates (D), internal hazard and external hazard index (Hex), and annual effective dose equivalent are 370 Bqkg-1, 0.27, 0.18, and 27.99 nGyh-1, respectively. The average annual effective dose is found 0.13 mSvy-1, which is less than the recommended value (1 mSvy-1) by the International Commission on Radiological Protection (ICRP-60, 1990), as the maximum permissible annual effective dose to the members of the public. The present study results are discussed and compared with those reported in similar studies and with internationally recommended values. No artificial radioactivity was found in the present study. The results show that the analyzed cement samples do not pose any significant radiation hazard from naturally occurring radionuclides 226Ra, 232Th and 40K reported here and also considered safe for use in buildings construction.
J. Bangladesh Acad. Sci. 45(1); 95-104: June 2021
UJI EFEKTIVITAS ASAP CAIR CANGKANG BUAH Hevea braziliensis TERHADAP AKTIVITAS BAKTERI Escherichia coli
Authors: Oktarina Dinda , Sumpono Sumpono , Elvia Rina 
Published: July 2021

This research purpose to determine the effectiveness of the liquid smoke of the Hevea braziliensis fruit shell against the activity of Escherichia coli bacteria. The preparation and purification of liquid smoke is carried out by 4 stages: pyrolysis , sedimentation, stage 1 and stage 2 distillation. This research was started with total acidity test, phenol level, pH and density with result of measurement 4,725% total acid content, 0,84% phenol content, 2,548 pH and 1,004 in density . An antibacterial test using disc diffusion method by looking at the diameter of the clear zone. There are six concentrations of liquid smoke of H.braziliensis rubber shell used, negative control using aquades and positive control using ciprofloxacin . An effective concentration was found in inhibiting E.coli is 100% concentration with a clear zone diameter of 11.3 mm. The result of analysis using One Way ANOVA showed F count (4.42)> F table (3,23), then H0 rejected, meaning there is a significant difference of influence of concentration to the diameter of clear zone produced.
PEMANFAATAN ARANG AKTIF SABUT KELAPA SAWIT SEBAGAI ADSOBEN ZAT WARNA SINTETIS REACTIVE RED-120 DAN DIRECT GREEN -26
Authors: Puspita Melfi , Firdaus M. Lutfi , Nurhamidah Nurhamidah 
Published: July 2021

The problem of environmental polution caused by waste of batik industry lately is increasing, so it needed a method to overcome that problem. The aim of this study was to determine the ability of activated charcoal from coconut fiber palm in adsorbing Reactive Red-120 and Direct Green-26 dyes in waste of batik along with determining the parameters of isotherms adsorption using UV-Vis Spectrophotometer analysis method. Variations of pH, contact time, adsorbent weight and temperature were carried out as variable to obtain optimum conditions of the adsorption process. The optimum of conditions for Reactive Red-120 occured at pH 3 and a contact time of 30 minutes, while Direct Green-26 occurred at pH 4 and a contact time of 40 minutes, with each adsorbent weight 150 mg and the temperature 30 °C. Adsorption isotherms determined by Freundlich and Langmuir models with maximum adsorption capacity (Qmax) were obtained for the Reactive Red-120 was 400 mg/g, while Direct Green-26 is 169 mg/g.
EKSPERIMEN KINETIKA ENZIM MENGGUNAKAN MODEL INKUIRI TERBIMBING UNTUK MENINGKATKAN KETRAMPILAN BERPIKIR KREATIF MAHASISWA
Authors: Amida Nadia , Supriyanti F.M. Titin , Liliasari Liliasari 
Published: July 2021

[EXPERIMENT OF ENZYME KINETICS USING GUIDED INQUIRY MODEL FOR ENHANCING CREATIVE THINGKING SKILLS] Purpose of this study was enhancing creative thinking skills of students using guided inquiry model through experiments of enzyme kinetics based on local materials. Method of this research was quasi-experimental methods, with pretest-posttest nonequivalent control group design. Subjects of this study were chemistry students enrolled in biochemistry lab course, consisted of 18 students in the experimental class and 19 students in control class. Instrument in this study were essay test that involves 3 indikators of creative thinking skills (i.e. fluency, flexibility, and elaboration) and also student worksheets. The results showed that the experiments of kinetics enzyme using guided inquiry model have been enhance creative thinking skills in medium category with a value of N-gain average of 0.66. Two indikators classified in the high category are fluency and elaborationwith the value of N-gain 0,71. Meanwhile, indikator of flexibility in the medium category with a value of N-gain 0,56.
PEMBUATAN DAN KARAKTERISASI METIL SELULOSA DARI BONGGOL DAN KULIT NANAS (Ananas comosus)
Authors: Rahmidar Lena , Wahidiniawati Seruni , Sudiarti Tety 
Published: July 2021

[MAKING AND CHARACTERIZATION OF CELLULOSE METHOD OF BONGGOL AND LEATHER LEATHER (Ananas comosus)] Wastes of core and peel of pineapple are often not utilized properly, in fact the waste has nutritional content that can be useful. Carbohydrate content in the waste is large enough and allows to be utilized. The purpose of this research is for converting glucose into cellulose and synthesized into methylcellulose. The first stage is glucose from core and peel of pineapple converted into microbial cellulose with Acetobacter xylinum bacteria with the addition of nitrogen and carbon sources. The second stage is synthesis of methylcellulose with methylene chloride and the solvent aquadest/acetone. The dried microbial cellulose was firstly swelled with NaOH addition, then methylation by addition of solvent and methylene chloride and then refluxed at 50-60. Then methyl cellulose neutralized, washed and dried at 50.The FTIR results showed typical cellulose uptake for cellulose microbial pineapple core at wave number 3377.36 cm-1 for OH bonds and 2935.66 cm-1 for CH bonds and in cellulose microbialpineapple peel at wave number 3377.36 cm-1 for OH bonds and 2935.66 cm-1 for the CH bonds. The ratio OH/CH of methyl cellulose-acetone has a smaller value in the core and peel of pineapple concluded that acetone is more efficient to use as a solvent at the methylation. The substitution value of the core and peel of pineapple skin is estimated to below based on the solubility test results.
Knockdown of Circular RNA hsa_circ_PVT1 Inhibited Laryngeal Cancer Progression via Preventing wnt4/β-Catenin Signaling Pathway Activation
Authors: Yu Feng , Lin Ying , Ai Mao-Mao , Tan Guo-Jie , Huang Jia-Li , Zou Zi-Rou 
Published: July 2021

AimTo explore the function and mechanism of circular has_circ_PVT1 on laryngeal cancer (LC).MethodsMicroarray chip was performed to screen the differential expression of circRNA. Western blot and qRT-PCR was employed to detect the protein and mRNA level. CCK-8, clone formation, cell cycle, wound healing, and Transwell assay were performed to detect the cell proliferation, migration, and invasion ability. Luciferase assay and Fish were used to confirm the relationship between circ_PVT1/CBX4 and miR-21-5p. Flow cytometry and TUNEL assay were carried out to assess the apoptosis level.ResultsThe upregulation of circ_PVT1 was found in LC tissues and cells. Silencing of circ_PVT1 inhibited LC progression via targeting miR-21-5p and indirectly controlling CBX4. Wnt4/β-catenin signal pathway was inactivated by inhibiting the expression of circ_PVT1.ConclusionKnockdown of circ_PVT1 prevented LC progression via targeting miR-21-5p/CBX4 by inhibiting wnt4/β-catenin signal pathway, which could provide a novel therapeutic target for LC.