bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of a Perinatal Palliative Care Model at a Level II Perinatal Center Supported by a Pediatric Palliative Care Network
Authors: Bolognani Marco , Morelli Paola Daniela , Scolari Isabella , Dolci Cristina , Fiorito Valentina , Uez Francesca , Graziani Silvia , Stefani Barbara , Zeni Francesca , Gobber Gino , Bravi Elena , Tateo Saverio , Soffiati Massimo 
Published: January 2021

Objective: To describe the model build up to take care of fetuses and newborns eligible to perinatal palliative care (PnPC) followed in an Italian II level perinatal center.Methods: Retrospective chart review of all fetuses and newborn infants eligible to PnPC admitted to level II perinatal center within a 4 years period.Results: Forty-five of 848 infants (0.5%) referred to II level NICU were eligible to PnPC. Twenty-seven percentage had fetal diagnosis. Twenty percentage were preterm infants at the limit of viability, 35% were newborns with life limiting or life threatening disease diagnosed in utero or at the postnatal ward, 45% were newborns not responding to intensive care intervention with high health care needs or medical complexity. Fifty-seven percentage of neonates admitted to NICU died before discharge, while 16 (35% of population considered) were discharged home. Median age at death was 4 days after birth, and delivery room death immediately after birth occurred in six patients (13%).Conclusions: Despite the paucity of our population and the high variability in disease trajectories the perinatal palliative care program build up in our region provides a reproducible method for a structured taking in charge of fetuses and neonates eligible to PnPC and their families, from the time of diagnosis to bereavement, in both outpatient and inpatient settings.
Calcium-Sensing Receptor Participates in High Glucose-Induced EndMT in Primary Human Aortic Endothelial Cells
Authors: Yuan Cheng , Ni Lihua , Yang Xianqin , Zhang Changjiang , Wu Xiaoyan 
Published: January 2021

ObjectivePrevious studies have shown that high glucose (HG) induces endothelial cell (EC) damage via endothelial-to-mesenchymal transition (EndMT). Although the underlying mechanisms are still unclear, recent studies have demonstrated the role of calcium-sensing receptor (CaSR) in mediating EC damage. Therefore, the aim of our study was to investigate whether CaSR mediates HG-induced EndMT and to determine the underlying mechanism.MethodsBioinformatics analysis of microarray profiles (GSE30780) and protein-protein interaction (PPI) analyses were performed to select the hub genes. As for in vitro research, the human aortic ECs (HAECs) were exposed to HG to induce EndMT. The expression of CaSR and β-catenin was determined, as well as their effects on EndMT (endothelial marker CD31, mesenchymal marker FSP1, and α-SMA).ResultsThe bioinformatics analysis indicated CaSR was significantly increased in HG-treated HAECs and was one of the hub genes. The in vitro results showed that HG significantly inhibited the expression of CD31 and increased FSP1 and α-SMA in a concentration- and time-dependent manner. Moreover, CaSR was increased in HAECs after HG treatment. The CaSR antagonist attenuated HG-induced expression of EndMT-related markers. Furthermore, HG treatment increased the nuclear translocation of β-catenin in HAECs. In contrast, blocking the nuclear translocation of β-catenin by DKK1 could attenuate HG-induced EndMT (increased the protein expression of CD31 by 30% and decreased the protein expression of FSP1 by 15% and α-SMA by 25%). CaSR siRNA further inhibited the HG-induced nuclear translocation of β-catenin in HAECs.ConclusionOur research demonstrated that HG-induced EndMT in HAECs might be mediated by CaSR and the downstream nuclear translocation of β-catenin.
Depression, Anxiety and Post-traumatic Growth Among Bereaved Adults: A Latent Class Analysis
Authors: Li Jie , Sun Yihua , Maccallum Fiona , Chow Amy Y. M. 
Published: January 2021

BackgroundThe death of a loved one can trigger a range of responses, including painful thoughts and emotions, as well as positive changes, such as post-traumatic growth (PTG). To understand more about the relationship between these outcomes this study explored the co-occurrence of depression, anxiety and PTG among a group of bereaved Chinese adults.MethodsData were collected from 194 participants, who had lost a first-degree relative. Latent class analysis was used to analyze the data to identify subgroups of participants with shared symptom profiles.ResultsThree classes were identified: a Growth class, a Depression/Anxiety/Growth class and a Depression/Anxiety class. Marital status, social support, close relationship with the deceased and witnessing the suffering of the deceased were identified as differential predictors of class membership.ConclusionThe findings contribute to our understanding of the potentially wide ranging impacts of bereavement and highlight the important role of stressor characteristics and support and in influencing impairment and positive outcomes.
Physical Activity Intensity Cut-Points for Wrist-Worn GENEActiv in Older Adults
Authors: Fraysse François , Post Dannielle , Eston Roger , Kasai Daiki , Rowlands Alex V. , Parfitt Gaynor 
Published: January 2021

Purpose: This study aims to (1) establish GENEActiv intensity cutpoints in older adults and (2) compare the classification accuracy between dominant (D) or non-dominant (ND) wrist, using both laboratory and free-living data.Methods: Thirty-one older adults participated in the study. They wore a GENEActiv Original on each wrist and performed nine activities of daily living. A portable gas analyzer was used to measure energy expenditure for each task. Testing was performed on two occasions separated by at least 8 days. Some of the same participants (n = 13) also wore one device on each wrist during 3 days of free-living. Receiver operating characteristic analysis was performed to establish the optimal cutpoints.Results: For sedentary time, both dominant and non-dominant wrist had excellent classification accuracy (sensitivity 0.99 and 0.97, respectively; specificity 0.91 and 0.86, respectively). For Moderate to Vigorous Physical Activity (MVPA), the non-dominant wrist device had better accuracy (ND sensitivity: 0.90, specificity 0.79; D sensitivity: 0.90, specificity 0.64). The corresponding cutpoints for sedentary-to-light were 255 and 375 g · min (epoch independent: 42.5 and 62.5 mg), and those for the light-to-moderate were 588 and 555 g · min (epoch-independent: 98.0 and 92.5 mg) for the non-dominant and dominant wrist, respectively. For free-living data, the dominant wrist device resulted in significantly more sedentary time and significantly less light and MVPA time compared to the non-dominant wrist.
Educational Methods of Engineering Training
Authors: Bagyinszki Gyula , Bitay Enikő 
Published: January 2021

Abstract
The choice and the appropriate combination of methods used in the teaching-learning (education – knowledge-acquisition) process in technical higher education depends to a large extent on the personality of the lecturer, his/her pedagogical culture, personal competences and of course, the technical possibilities at his/ her disposal. This study provides a concise overview of the methods as tried-and-tested systems of consciously implemented operations and means that are systematically used by the lecturer to achieve the objectives of training in practical cooperation with the students.
Innovation Design for Safe Products
Authors: Csongvai Roland , Torkos Zoltán 
Published: January 2021

Abstract
Innovation & product safety in the case of the EC & Hungarian SMEs is a top priority, where product safety is also a legal obligation. Despite this, innovation design is dealt with inadequately by the majority of companies, and this is due to lack of knowledge or competency, especially considering the processes related to the design of safe products. Improper behaviour in the design stages results in losses for the companies - losses due to the inadequacy of otherwise innovative products. Inadequate or poorly applied directives/policies, especially when coded into processes influence not only the safety of the products but can result in delays to market access, significantly increasing costs & development time, as well jeopardising the product’s acceptance on the future market.
A Cost Effective Rapid Weld Technology Configuration
Authors: Laki Márk , Kuti János 
Published: January 2021

Abstract
The research focuses on determining the application parameters of a new process developed by Cloos. With the use of Cloos Rapid Weld technology (metal active gas welding), the authors carried out welding experiments on S235JR steel sheets (6 mm and 8 mm thick). The results of the welding experiments were verified by hardness measurement [1–3]. The goal is to establish one side one row suitable welded joint by the used technology.
Investigations of Detergents and Metal Components for Supporting the Effective Treatment of Greywater
Authors: Lós Réka , IzbékinéSzabolcsik Andrea , Bodnár Ildikó 
Published: January 2021

Abstract
The aim of our research was to investigate the detergent content and several micro and macro elements in greywater samples, a necessary step in determining the water quality for the further reuse of the greywater. We determined the anionic detergent content of synthetic greywater with a two-phased titration method prepared in laboratory conditions. The current study leads to a new suggestion for a more accurate and reliable titrimetric method for determination of anionic detergent content of synthetic greywater samples. Following these investigations, we also examined the metal content of synthetic bath water. We wanted to highlight how detergents in greywater influence the micro and macro element content of the given synthetic bath water samples.
The Impact of Active Cooling on Heat Resistant PLA
Authors: Lukács Norbert László , Ficzere Péter , Szebényi Gábor 
Published: January 2021

Abstract
In this study the properties of HT-PLA were determined with tensile tests. The influence of cooling was determined and influence of manufacturing environment shown to be predictable. Heat resistant 3D printing materials can be widely used in the manufacturing process but these materials are relatively expensive. HTPLA is one of the cheapest materials with these parameters.
Numerical Modelling of the Three-Roll Bending Process of a Thin Plate
Authors: Máté Péter , Szekrényes András 
Published: January 2021

Abstract
The three-roll bending process is a simple procedure, commonly used in the industry, through which a cylindrical surface can be produced from a sheet plate. This process is mainly controlled through experience and it is described with the finite element method, except for a very few numerical and analytical investigations. The topic of this article is to present a numerical method, through which the curvature function along the rolling direction can be calculated. This article presents the proposed numerical method and its verification with the finite element method. The results of the two numerical methods are in good agreement.
El conocimiento pedagógico del contenido (CPC) por el profesor universitario en el uso del método de resolución de problemas
Authors: Agudelo Arteaga Karen Patricia , Flórez Nisperuza Elvira Patricia , Ravanal Moreno Eduardo , Figueroa Molina Roberto 
Published: January 2021

El estudio propone la caracterización del Conocimiento Pedagógico del Contenido, declarado por el profesor universitario de ciencias experimentales en el uso del método de Resolución de Problemas en una universidad pública en Colombia. Para tal fin, se hace uso del cuestionario de Representación del Contenido (ReCo) para generar mapa del CPC de seis (6) profesores de ciencias experimentales. Los resultados permitieron identificar las relaciones que se establecen entre los componentes del Conocimiento Pedagógico del Contenido (CPC) en el uso del método de resolución de problemas. Se concluye que cada profesor construye sus propias relaciones a partir de su formación o experiencia.
MATHEMATICAL MODEL OF A MODIFIED ROTMAN LENS BASED ON AN ASYMMETRIC STRIPE LINE
Authors: Пастернак Ю.Г. , Пендюрин В.А. , Сафонов Ф.С. 
Published: January 2021

Печатные линзы Ротмана из-за своей достаточной простоты построения и за свои широкополосные свойства, а именно за счет коэффициента частотного перекрытия (может достигать 2-3 и даже более), являются одним из основных перспективных направлений для формирования лучей в многолучевых антенных решетках (МАР). Принцип работы таких линз основан на различных путях распространения волны внутри ее структуры, благодаря которому линза может работать в сверхширокой полосе частот. Но из-за этого возникает новая проблема, а именно: увеличение габаритных размеров антенной системы. Вследствие чего такую конструкцию очень сложно интегрировать в компактную систему приемопередатчика. Эту проблему предлагается решить путем разработки более компактной линзы Ротмана, сложенной пополам. Такой кардинальный метод изменения (уменьшения) габаритных размеров линзы Ротмана мы объясняем тем, что основным типом волны, переносящим подавляющую долю энергии, является волна ТЕМ, для которой практически отсутствует дисперсия в СВЧ-ламинатах с малыми потерями. А для радиолокации, радиопеленгации и связи нужны именно такие способы решения технических трудностей. Но перед тем как создать опытную модель или макет антенной решетки, необходимо провести ряд экспериментов, расчетов и подтвердить заданные технические характеристики ФАР. В данной работе была создана и посчитана математическая модель линзы Ротмана, основанная на том, что ее свернули пополам
Rotman printed lenses are one of the main promising directions for ray formation in multipath antenna arrays (MAA) due to their sufficient simplicity of construction and their wide-band properties, namely, due to the frequency overlap coefficient (it can reach 2-3 or even more). The principle of operation of such lenses is based on different paths of wave propagation within its structure, thanks to which the lens can work with an extremely wide frequency band. However, because of this, a new problem arises - an increase in the overall dimensions of the antenna system. As a result, this design is very difficult to integrate into a compact transceiver system. This problem is proposed to be solved by developing a more compact Rotman lens folded in half. We explain this cardinal method of changing (reducing) the overall dimensions of the Rotman lens by the fact that the main type of wave that transfers the overwhelming share of energy is the TEM wave, for which there is practically no dispersion in microwave laminates with small losses. And for radar, radio direction finding and communication, these are the ways to solve technical difficulties. Before creating an experimental model or layout of the antenna array, it is necessary to conduct a number of experiments, calculations and confirm the specified technical characteristics of the PAA. In this paper, a mathematical model of the Rotman lens was created and calculated based on the fact that it was folded in half
Типологічне різноманіття рекреаційно-оздоровчих лісів Лівобережної України
Authors: Musienko S. I. , Lukyanets V. A. , Bondarenko V. V. , Rumiantsev M. H. , Kobets O. V. 
Published: January 2021

Вивчено типологічне різноманіття рекреаційно-оздоровчих лісів Лівобережної України за природними зонами: Лівобережне Полісся; Лівобережний Лісостеп та Лівобережний Степ. Досліджено різноманіття типів умов місцезростання рекреаційно-оздоровчих лісів залежно від їх розташування: у межах міст, селищ та інших населених пунктів; у межах округів санітарної охорони лікувально-оздоровчих територій і курортів; у межах поясів зон санітарної охорони водних об'єктів у лісах; зелених зон навколо населених пунктів; поза межами лісів зелених зон. Встановлено, що для рекреаційно-оздоровчих лісів Лівобережної України характерна вся широта як трофогенного, так і гігрогенного рядів. Найбільша частка площі та запасу насаджень зосереджена в умовах дібров, а найменша – в умовах борів. Найбільше значення середнього запасу на 1 га відзначено в умовах суборів, а найменше – в умовах дібров. Серед гігротопів панівне становище займають насадження, що ростуть в свіжих умовах. Незначною є частка насаджень, що ростуть в дуже сухих умовах. Визначено, що більшість насаджень в рекреаційно-оздоровчих лісах ростуть в умовах свіжих грудів. У Лівобережному Поліссі переважають борові умови за трофністю і свіжі – за зволоженням. У Лівобережному Лісостепу найбільші площі займають лісові ділянки в умовах свіжих грудів. Насадження Лівобережного Степу ростуть переважно на багатих та зволожених ґрунтах. Ці особливості потрібно врахувати під час планування та здійснення відповідних лісогосподарських заходів, спрямованих на вирощування високопродуктивних, стійких, довговічних і високодекоративних насаджень, які ефективно виконуватимуть важливі еколого-захисні функції. Перспективним залишається питання щодо збільшення видового різноманіття в рекреаційно-оздоровчих лісах Лівобережної України, зокрема за рахунок інтродукованих деревних та чагарникових видів, для підвищення їхніх екологічних та естетичних властивостей.
PENGARUH MODEL PEMBELAJARAN GENERATIF UNTUK MENINGKATKAN KEMAMPUAN KONEKSI MATEMATIS SISWA KELAS III
Authors: Roni Hamdani Acep , Putri Ayu Puput 
Published: January 2021

This study aims to determine the effect of generative learning models to improve the mathematical connections of elementary school students. This research was conducted at SDN Tanjungwangi in the academic year 2020/2021 with a research sample of 20 class III A students and 20 class III B students. This research method uses a quasi-experimental method. The data analysis technique in this study uses the N-gain calculation to measure the increase in the ability of students 'mathematical connections, (t-test) to determine the effect of using generative learning models on students' mathematical connection abilities. The results showed that (1) there was an increase in the mathematical connection ability with an average N-gain in the experimental class, the result was 0.79 with the "high" criteria and the average N-gain on the control was 0.05 with the criteria "very low" . (2) there is an effect of using generative models on the ability of mathematical connections with the results of tcount <t table 0.830 <2.024. Thus, it can be concluded that the influence of the generative learning model on the mathematical connection ability of elementary school students.
Keywords: Mathematical Connection Ability, Genertive Learning Model
TESS Hunt for Young and Maturing Exoplanets (THYME). IV. Three Small Planets Orbiting a 120 Myr Old Star in the Pisces–Eridanus Stream*
Authors: Newton Elisabeth R. , Mann Andrew W. , Kraus Adam L. , Livingston John H. , Vanderburg Andrew , Curtis Jason L. , Thao Pa Chia , Hawkins Keith , Wood Mackenna L. , Rizzuto Aaron C. , Soubkiou Abderahmane , Tofflemire Benjamin M. , Zhou George , Crossfield Ian J. M. , Pearce Logan A. , Collins Karen A. , Conti Dennis M. , Tan Thiam-Guan , Villeneuva Steven , Spencer Alton , Dragomir Diana , Quinn Samuel N. , Jensen Eric L. N. , Collins Kevin I. , Stockdale Chris , Cloutier Ryan , Hellier Coel , Benkhaldoun Zouhair , Ziegler Carl , Briceño César , Law Nicholas , Benneke Björn , Christiansen Jessie L. , Gorjian Varoujan , Kane Stephen R. , Kreidberg Laura , Morales Farisa Y. , Werner Michael W , Twicken Joseph D. , Levine Alan M. , Ciardi David R. , Guerrero Natalia M. , Hesse Katharine , Quintana Elisa V. , Shiao Bernie , Smith Jeffrey C. , Torres Guillermo , Ricker George R. , Vanderspek Roland , Seager Sara , Winn Joshua N. , Jenkins Jon M. , Latham David W. 
Published: January 2021

Abstract
Young exoplanets can offer insight into the evolution of planetary atmospheres, compositions, and architectures. We present the discovery of the young planetary system TOI 451 (TIC 257605131, Gaia DR2 4844691297067063424). TOI 451 is a member of the 120 Myr old Pisces–Eridanus stream (Psc–Eri). We confirm membership in the stream with its kinematics, its lithium abundance, and the rotation and UV excesses of both TOI 451 and its wide-binary companion, TOI 451 B (itself likely an M-dwarf binary). We identified three candidate planets transiting in the Transiting Exoplanet Survey Satellite data and followed up the signals with photometry from Spitzer and ground-based telescopes. The system comprises three validated planets at periods of 1.9, 9.2, and 16 days, with radii of 1.9, 3.1, and 4.1 R
⨂, respectively. The host star is near-solar mass with V = 11.0 and H = 9.3 and displays an infrared excess indicative of a debris disk. The planets offer excellent prospects for transmission spectroscopy with the Hubble Space Telescope and the James Webb Space Telescope, providing the opportunity to study planetary atmospheres that may still be in the process of evolving.
Sensitivity Reach of Gamma-Ray Measurements for Strong Cosmological Magnetic Fields
Authors: Korochkin Alexander , Kalashev Oleg , Neronov Andrii , Semikoz Dmitri 
Published: January 2021

Abstract
A primordial magnetic field with strength in the 1–10 pG range can resolve the tension between different measurements of the Hubble constant and provide an explanation for the excess opacity in the 21 cm line at redshift 15 < z < 20 if it is present during the recombination and reionization epochs. This field can also survive in the voids of the large-scale structure in the present day universe. We study the sensitivity reach of the gamma-ray technique for measurement of such a relatively strong cosmological magnetic field using deep exposure(s) of the nearest hard spectrum blazar(s) with CTA telescopes. We show that the gamma-ray measurement method can sense the primordial magnetic field with a strength of up to 10−11 G. Combination of the cosmic microwave background and gamma-ray constraints can thus sense the full range of possible cosmological magnetic fields to confirm or rule out their relevance to the problem of the origin of cosmic magnetic fields, as well as their influence on recombination and reionization epochs.