bluuebunny/crossref_metadata_2025_split huggingface dataset:
First wolves in Luxembourg since 1893, originating from the Alpine and Central European populations
Authors: Schley Laurent , Jacobs Marianne , Collet Sebastian , Kristiansen Alexander , Herr Jan 
Published: January 2021

Abstract
Considering the spread of the grey wolf (Canis lupus) in Europe over the past 30 years, Luxembourg took some measures to prepare for the return of this apex predator, including the establishment of a management plan that notably addresses the issue of wolf depredation on livestock. Here we present the results of genetic analyses of putative wolf saliva, hair and scat samples collected from or near prey carcasses between 2015 and 2020. In two cases, the wolf was confirmed via DNA analysis: in July 2017 near Garnich and in April 2020 near Niederanven, both assigned to category C1 (hard evidence). A third case was classified as C2 (confirmed observation) based on prey carcass characteristics, while genetic analysis yielded no result. These are the first confirmed records of wolves in Luxemburg since 1893. Moreover, the two C1-cases originated from the Alpine (Garnich) and Central European (Niederanven) populations. Given similar developments in the neighboring countries and regions, we conclude that the area including the Benelux countries as well as Rhineland-Palatinate, Saarland and Northern France may well become a melting pot for wolves of the two aforementioned populations in the coming years and decades.
Surgical Correction of Cardiac Defects with Ellis Van Crevald Syndrome – A Rare Case Report
Authors: Choudhury DIR , DasGupta Saikat , Uddin Mauin , Howlader Siddhartha Shankar , Chanda PK , Rahman ATMK , Ahmed Farooque 
Published: January 2021

Ellis-Van Creveld (EVC) syndrome is an autosomal recessive disorder. Around 150 cases are described in published literature and in Bangladesh, it is even rare. The patient usually comes with short stature, dental deformity, and cardiac deformity. Here, we present the case of a patient with ostium primum atrial septal defect (ASD) with moderate mitral regurgitation who underwent surgical repair of ASD and mitral valve replacement.
Government's management concept in economy stabilization during the crisis
Authors: Kolosov Andrey , Kucherenko Sergey 
Published: January 2021

Purpose – to identify weaknesses and advise the Ukrainian Government's managerial concept in economic stabilization during the crisis. There were applied system's methods and functional analysis and control systems' synthesis.
Findings. It was established that the country has no institute for monitoring and developing a strategy for macroeconomic regulation during the crisis, the Government's inability to compensate for the lack of conceptual substantiation for its decisions, most of which are not timely brought to the final economic entities that negatively perceive the Government's regulatory decisions, suspending from their implementation and even resorting to resistance. Significant deficiencies in the Government's regulatory activities during the crisis were identified, which demands its improvement based on managing economic entities' behavioral concepts in changing environments. Proposals for the selecting behavioral imperative for Ukraine's economy during the crisis and regulatory decisions were developed, considering changes in the management object's stability.
Theoretical and practical implications. The research's theoretical significance is to substantiate the Government's managerial concept during the crisis, and when the possibility of its direct application determines the practical significance.
Originality/Value. The research's novelty is the behavioral theory's elements application for Government activities.
Research limitations/Future Research. Prospects for further research are related to the substantiation and development of a government's holistic management model during the crisis. The article is theoretical and empirical.
Paper type – theoretical.
The importance of circulating tumor markers in lung cancer in clinical practice
Authors: Rykov I. V. 
Published: January 2021

We have reviewed the available publications about circulating tumor markers (CTM) — CYFRA 21‑1, CEА, SCC, NSE and proGRP, in patients with small‑cell (SCLC) and non‑small cell lung cancer (NSCLC). Elevated levels of at least one of them (CEA, CYFRA 21‑1 и SCC) were seen in 100 % of patients with stage III–IV NSCLC. CEA, CYFRA 21‑1 and SCC could have prognostic and predictive value. Their decrease during chemotherapy or immunotherapy correlates with better overall survival. For SCLC the main CTM are NSE and proGRP. Together with CTM for NSCLC these markers could predict correctly histological subtype of lung cancer in 79–97 % of patients. Levels of proGRP after 1, 2 and 3 cycles of chemotherapy in SCLC correlated with response to treatment and were associated with prognosis. Thus, it can be used as an additional response criterion, for example in patients with non‑measurable disease. CTM provide additional easy‑to‑use predictive and prognostic data for patients with lung cancer.
The role of the neoadjuvant approach in the treatment of primary operable HER2 positive breast cancer
Authors: Frolova M. A. , Glazkova Е. V. , Petrovsky A. V. , Krokhina О. V. , Stenina M. В. , Tyulyandin S. A. 
Published: January 2021

Neoadjuvant systemic therapy is an essential component of the comprehensive treatment of primary operable HER2‑positive breast cancer. Therefore, it is extremely important to search for treatment efficacy predictors and optimal system for assessing tumor response to treatment. The study analyzed factors predicting pathological complete response (pCR) in patients with luminal and non‑luminal HER2‑positive tumor subtypes. The morphological assessment of the tumor response to treatment was carried out using the RCB system; additional characteristics of the residual tumor were studied as well. It was shown that a comprehensive assessment involving the use of the RCB system and determination of the Ki ‑ 67 level helps to divide patients into prognostic groups and individualize the adjuvant therapy plan.
Comparison of surgical technique and outcomes of phacoemulsification and manual small incision cataract surgery in management of phacomorphic glaucoma and analysis of the risk factors for developing phacomorphic glaucoma
Authors: Bhatt Jyoti , Singh Sindhuja , Chaudhary Prakhar , Bhardwaj Rahul , Singh Kunal Vikram , Bhadauria Madhu 
Published: January 2021

Background: Phacomorphic glaucoma is highly prevalent in developing countries. In India, the prevalence of phacomorphic glaucoma is 3.91%. The definitive treatment of phacomorphic glaucoma is surgery. The purpose of our study was to compare the surgical technique and outcomes of phacoemulsification and manual small incision cataract surgery (MSICS), in management of phacomorphic glaucoma and analysis of the risk factors for developing phacomorphic glaucoma. Methods: This was a hospital based retrospective study done at a tertiary eye care center, over a period of nineteen months. A rigorous protocol to diagnose phacomorphic glaucoma was followed. All patients were given IV mannitol 20%, before surgery. The study patients were divided in to phaco group and MSICS group. The data analysis was done using Statistical Package for Social Sciences (SPSS) version 21.0. Results: Out of 99 phacomorphic glaucoma cases, 37 underwent phacoemulsification and 62 underwent MSICS. The total number of female patients was 66 (66.67%) and that of male was 33 (33.33%) with female to male ratio of 2:1. The mean age of presentation was 63.64±8.27 years. The overall mean IOP was 42.9±9.68 mmHg in both the groups. The mean axial length was 22.47±1.03 mm in study patients and 22.82±0.8 mm in control group, (p=0.0082). The mean AC depth was 2.54±0.53 mm for phacomorphic eyes and 2.69±0.5 mm for control groups, (p=0.04). Conclusions: MSICS is effective, safe and inexpensive in controlling IOP and achieving good visual acuity with minimal complications in the management of phacomorphic glaucoma as compared to phacoemulsification.
The Effect of Resistance Training on Malondialdehyde and Protein Carbonyl Concentration in the Heart Tissue of Rats Exposed to Stanozolol
Authors: Arjmand Ayat , Abedi Bahram , Hosseini Seyed Ali 
Published: January 2021

Background: Consumption of anabolic steroids causes damage to various tissues, including the heart.
Objectives: This study aimed to investigate the effect of Resistance Training (RT) on Malondialdehyde (MDA) and Protein Carbonyl (PC) in the heart tissue of rats exposed to stanozolol (S).
Methods: In this experimental study, 18 rats with the mean age of 8 weeks and weight range of 150 to 200 g were selected and divided into three groups of 6 rats: 1. Sham (normal saline consumption) (Sh), 2. S, and 3. S+RT. For 8 weeks, the S and S+RT groups received 5 mg/kg/d S, and the S+RT group performed 5 RT sessions per week. Measurement of MDA and PC in the heart tissue was performed with the enzyme-linked immunosorbent assay.
Results: Stanozolol had a significant effect on increasing MAD (P=0.001) and PC (P=0.03) in the heart tissue. However, RT led to a decrease in MDA and PC in the heart tissue of rats exposed to S (P=0.001).
Conclusion: It appears that S consumption leads to an increase in MDA and PC levels in the heart tissue, while RT can improve the elevated levels of MDA and PC.
The Effect of Acid Modification of Porcine Mucin on Its Drug Release and Skin Permeation Properties in Insulin Transdermal Films
Authors: Eraga Sylvester O. , Arhewoh Matthew I. , Iwuagwu Magnus A. 
Published: January 2021

Background: The transdermal delivery of insulin involving the use of polymers has been extensively reported. More recently, the use of mucoadhesive or bioadhesive polymers as an insulin base in its formulation is gaining attention possibly due to the penetration enhancing properties of the polymers.
Objectives: This study aimed at determining the effect of acid-modified porcine mucin powder on the release and permeation of insulin in transdermal films.
Methods: Various batches of insulin films were prepared by solvent casting method using polysorbate 80 as an emulsifying agent and acid-treated and untreated mucin powders as a base. The films were evaluated for their physical properties, folding endurance, moisture content and uptake, drug content, bioadhesion, in vitro release, ex vivo permeation, and in vivo glucose-lowering activity.
Results: The prepared insulin films had a weight range of 0.21-0.27 g, folding endurance of 101-103, moisture content and uptake of 13.73%-18.57% and 11.70%-22.30%, respectively, and drug content of 96%-101%. The bioadhesion of the films prepared with acid-treated mucin was within the range of 0.088-0.186 Nm-1 as against 0.055 Nm-1 of the films prepared with untreated mucin. The in vitro release profiles showed a release of 95% insulin from films prepared with untreated mucin within 2 h while the films made with acid-treated mucin gave a release of about 60%-73% over the same period, indicating a slower release. Animals that received acid-treated mucin-base insulin films showed delayed but sustained blood-glucose-lowering up to 70% and for films prepared with untreated mucin 55% within 12 h.
Conclusion: Insulin transdermal films prepared with acid-modified mucin powder gave superior bioadhesive strength values. They also showed improved drug permeation enhancing ability and achieving up to 70% blood glucose lowering in diabetic rats.
ZAKAT MANAGEMENT AND POVERTY ALLEVIATION IN INDONESIA
Authors: Maghfirah Maghfirah 
Published: January 2021

Zakat is potential to reduce the poverty number in Indonesia. The professional and effective management is the main key to achieve this target. This article analyzes the effectiveness of zakat distribution in Badan Amil Zakat Nasional (Baznas), Pekanbaru City in accordance with the Law No. 23 of 2011. The article is based on the doctrinal legal research with sociological approach. The data is collected through interview, documentation, and observation by analyzing the data in inductive, deductive, and comparative ways. The result reveals that zakat management in Baznas Pekanbaru is not effective yet in its effort to improve mustahiq (zakat receivers) economy. Of all effective strategies to collect the funds are: 1) government total intervention in collecting and distributing the zakat funds, 2) socialization to the community to pay zakat via Baznas, 3) Improving Baznas’ human resources and management, 4) Implementing the expansion concept in zakat obligation. Meanwhile, the effective strategy in zakat funds distribution is classifying mustahiq into two groups i.e. mustahiq jabariah and mustahiq khiyariah with different model approach.Zakat berpotensi besar menjadi sarana mengurangi angka kemiskinan di Indonesia. Pengelolaan yang professional dan efektif menjadi kunci utama mencapai tujuan ini. Artikel ini bertujuan menganalisis efektivitas penyaluran zakat di Badan amil zakat nasional Pekanbaru menurut Undang-Undang No. 23 Tahun 2011. Artikel ini berdasarkan penelitian hukum diktrinal dengan pendekatan sosiologis. Metode pengumpulan data adalah wawancara, dokumentasi dan observasi dengan analisis data secara induktif, deduktif dan komparatif. Hasil dari penelitian ini menjukkan bahwa manajemen zakat di Baznas Pekanbaru belum efektif dalam upaya meningkatkan ekonomi mustahiq. Adapun strategi efektivitas penghimpunan dana yaitu; (1) intervensi pemerintah secara menyeluruh dalam penghimpunan dan penyaluran dana zakat, (2) sosialisasi kepada masyarakat agar berzakat melalui Baznas, (3) meningkatkan Sumberdaya Manusia dan manajemen Baznas, dan (4) menerapkan konsep perluasan dalam kewajiban zakat. Sedangkan strategi efektivitas distribusi dana zakat adalah melakukan pengklasifikasian mustahiq kepada dua kelompok, yakni mustahiq jabariah dan mustahiq khiyariah dengan model pendekatan yang berbeda.
Legacy of M. S. Strogovich and Modern Problems of Functional-Legal Construction of Criminal Pre-Trial Proceedings
Authors: Derishev Yu. V. 
Published: January 2021

In November 2019, the world legal community widely celebrated the 125th anniversary of Professor M. S. Strogovich, who, according to his scientific colleagues and students, was a scientist who was “ahead of time”.This article provides a retrospective and comparative analysis of the positions of M. S. Strogovich and his colleagues on certain problems of domestic criminal proceedings, in particular its pre-trial phase, in the context of the direct influence of the scientist's scientific heritage on the development of modern criminal procedure law. The Author of the article particularly interesting views of the scientist and his participation in discussions related to defining the essence and purpose of the preliminary investigation, the implementation of the functions of preliminary investigation in relation to criminal prosecution, the problems of implementation of the principles of presumption of innocence and the adversarial nature of pre-trial proceedings in criminal cases, and, finally, the General Manager of the “investigative case” in modern Russia.M. S. Strogovich consistently adhered to the idea of the need to develop and strengthen procedural guarantees of individual rights, guarantees of justice, and this can be seen in this article. Thus, defining the essence of the criminal process as a system of actions of the relevant officials and the procedural legal relations that arise in connection with them, which in itself was a serious “scientific courage” of those years, M. S. Strogovich particularly defended the position that all participants in criminal proceedings are subjects of the rights granted to them and the duties assigned to them, and they should not be considered objects of unilateral power of officials. This idea has become widespread and generally accepted as the basic definition of domestic (Soviet and Russian) criminal proceedings.The article analyzes M. S. Strogovich’s scientific steps on the conceptual turn from revolutionary-radical ideas about the construction of criminal proceedings to its classical canons and traditions of the Russian criminal process, On the basis of which the conclusion is made about the indispensable use of the scientist's legacy in modernьRussian procedural studies.The research of M. S. Strogovich’s legacy carried out in the article will fully allow to rethink the modern system of criminal proceedings in a new way, can be used as a kind of key to finding solutions to law-making and law enforcement problems, for the further development of the national science of criminal procedure law.
AN ANALYSIS OF PARENT-TEACHER COMMUNICATION TOWARD THE STUDENTS’ READING COMPREHENSION
Authors: Burhan Burhan , Malik Agung Rinaldy , Rusdin Diyenti , Marzuki Marzuki 
Published: January 2021

ABSTRACT
The aims of this research are to find out that extent parents are involved in their children reading comprehension at home and to know the factors trigger the communication between parents and the English teacher toward the students reading comprehension. By using the qualitative research this study described the research finding using a triangulation technique to gather the data from the questionnaires, interview, and Focus Group Discussion (FGD) from 10 parents and one english teacher at SMA Negeri 1 Lampasio. The data analysis indicates two things. The first, parents role toward the students’ reading comprehension is Low. It was found by the result of questionnaire that showed there were 10%-20% parents involved in their child reading comprehension at home. The second, the factors triggers the communication between parents and the English teacher were progress report that given by the English teacher to parents used an examination sheet and the same living place between parents and the English teacher.
Keywords: Parent-Teacher Communication, Reading Comprehension
FEMINISME PADA NOVEL CINTA SUCI ZAHRANA KARYA HABIBURRAHMAN EL SHIRAZY
Authors: Andes Andestend 
Published: January 2021

ABSTRAK
Karya sastra memang menjadi wadah bagi para penulis untuk mencurahkan pandangan, pendapat, kritikan, dan hal lainnya dalam bentuk sebuah karya sastra. Karya sastra memiliki gaya penulisan dan pandangan masing-masing salah satunya Feminisme. Feminisme memang menjadi kajian yang menarik oleh berbagai kalangan. Penelitian ini membahas tentang ide feminisme pada novel Cinta Suci Zahrana karya Habiburrahman El Shirazy. Metode penelitian kualitatif dengan studi pustaka jadi tidak terikat oleh tempat penelitian. Hasilnya ditemukan ide feminisme di dalam novel Cinta Suci Zahrana, dibuktikan dengan menuntut kesamaan derajat antara laki-laki dengan perempuan. Salah satu bukti autentik di dalam novel ketika Zahrana ingin sekolah tinggi karena dengan sekolah yang tinggi maka perempuan dapat menyetarakan kedudukan laki-laki, sehingga Zahrana lupa dengan usia yang sudah lanjut sewajarnya usia 35 tahun itu perempuan sudah menikah dan menjadi seorang Ibu.
Kata kunci: sastra, novel, ide feminisme
VALUE OF LOCAL WISDOM IN THE MYTH OF MERIAM TEGAK AND THE LEGEND OF PILANG ISLAND
Authors: Suhardi  , Andheska Harry , Sari Cut Purnama 
Published: January 2021

ABSTRACT
The purpose of this research is to explore the values of local wisdom contained in the myth of Meriam Tegak and the legend Pilang Island. The research method used is qualitative descriptive. Data collection techniques are carried out using document techniques. Analysis of research data is carried out using content analysis techniques. The results obtained are the myth of the upright cannon and the legend of Pilang Island contains the value of local wisdom, such: (1) religious, (2) honesty, (3) not denouncing, (4) keeping the heart, (5) patient, (6) meek, (7) responsibility, and (8) the value of trust. The conclusion of the research is the myth of Meriam Tegak and the legend of Pilang Island contains religious values (Islam), ethical values, social, hard work, and educational values. The eight values of local wisdom combine to build a whole storyline of myths and legends. In addition, the eight values also decrypt local wisdom values.
Keywords: values of local wisdom, myths, and legends
Konsep Komunikasi Dakwah Berbasis Budaya Jawa: Representasi Nilai-Nilai Islam Dalam Serat Dewa Ruci Tembang Macapat
Authors: Ahmad Nur , Suroiyya Serin Himatus 
Published: January 2021

<p>Komunikasi dakwah berbasis Budaya Jawa dapat dilakukan melalui berbagai bentuk budaya, salah satunya karya sastra Serat Dewa Ruci. Karya ini bercerita tentang perjalanan Bima mencari air suci. Meskipun Serat Dewa Ruci merupakan adopsi dari kebudayaan Hindu-Budha, namun cerita ini tetap banyak memuat ajaran-ajaran Islam secara eksplisit. Penelitian adalah termasuk dalam studi kepustakaan yang bertujuan untuk mendeskripsikan : Pertama, Kontribusi komunikasi dakwah berbasis budaya Jawa. Kedua, representasi nilai-nilai Islam yang terkandung dalam Serat Dewa Ruci. Teks Serat Dewa Ruci yang tertulis dalam bentuk tembang macapat. Dari keseluruhan cerita hanya dipilih pupuh Dhandhanggula dan pupuh Kinanthi. Pada artikel ini berhasil menemukan : Pertama, Kontribusi komunikasi dakwah berbasis budaya Jawa yang dibedakan ke dalam tiga bidang yakni : a) bidang agama yaitu memudahkan masuknya agama Islam kepada masyarakat Jawa. b) bidang sosial dan budaya yaitu menegakkan ukhuwah antar warga masyarakat. c) bidang kesenian dan tradisi yaitu menambah dan menjaga kelestarian budaya. Kedua, Representasi nilai-nilai Islam digambarkan melalui berbagai tindakan, perkataan, dan perbuatan dalam cerita Serat Dewa Ruci. Ada tiga nilai yang ditemukan yaitu: a) nilai akidah, memuat iman kepada Allah Swt berserta sifat-sifatNya dan iman kepada qada dan qadar. b) nilai syariah, memuat perintah untuk menahan hawa nafsu. c) nilai akhlak, memuat tentang ikhlas, sabar, dan <em>tawadhu’</em>.</p>
The Meaningfull Of Life Post-Psychosis Patient: Logotherapy Practices in Perspective Of Islamic Psychotherapy
Authors: Nida Fatma Laili , Syukur Muhammad Amin , Sulaiman Sulaiman 
Published: January 2021

<p>One of the fundamental problems in mental recovery of post-psychosis patients is the loss of meaning in life (meaningless). The feeling of meaningless becomes an obstacle to the recovery process which leads to re-treatment. To restore meaning to life, Victor E. Frankl offers the concept of logotherapy as a method of therapy to help bring meaning to life for every individual. This paper aim to explore indications of the logotherapy as a method used by therapists to assist the mental recovery process of post-psychosis patients at the Jalma Sehat Kudus Mental Rehabilitation Center, as well as how Islamic psychotherapy views it. This research is field research and descriptive qualitative as design, with data collecting through observation, interview and documentation methods. Based on the data obtained, in terms of self-development efforts and the applied therapeutic methods, it shows an indication of the application of the methods in Logotherapy. Self-development efforts are carried out through empowerment activities in social and economic activities that simultaneously with the application of spiritual guidance methods. The formation of attitudes and behaviors that are responsible, independent and have good social skills is an indication of the successful achievement of meaning in life. Although Frankl defines logotherapy as a secular method, in this research it is found that the harmony between the application of logotherapy and the concept of mental health contained in Islamic Psychotherapy with a meeting point on the spiritual aspect.</p>