bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interharmonic current sharing in islanding operation of inductive microgrid via enhanced I‐P droop scheme
Authors: Razi Reza , Iman‐Eini Hossein , Hamzeh Mohsen , Hably Ahmad , Bacha Seddik 
Published: September 2021

AbstractThe considerable expansion of non‐linear loads with interharmonic currents characteristic such as induction furnace, cycloconverter and variable‐speed drive is one of the new and important challenges in the control of industrial microgrids. For this reason, this paper presents an enhanced control scheme that tries to share power and especially interharmonic currents through parallel inverters accurately, which is not addressed in previous literature. In this regard, assuming the inherent delays of digital control, the proposed control strategy firstly suppresses the inherent impedances of inverters, especially in interharmonic frequencies. Then, the enhanced impedance‐power (I‐P) droop scheme is employed based on virtual inductors to compensate for the mismatch of line impedances and to achieve proper power‐sharing. Besides, novel techniques are introduced in the proposed structure to limit the values of virtual inductances and even to benefit from the negative virtual impedance method. The notable feature of the presented scheme is the sharing of interharmonic currents with high accuracy and low computations. Finally, the effectiveness of the proposed method is evaluated through simulation and experimental results.
The lacking interest in interest rates: will the phase-out of LIBOR and negative rates go unnoticed by arbitration practitioners?
Authors: Kalinin Mikhail , Peer Michael 
Published: September 2021

Abstract
Interest plays a crucial role in ensuring that the compensation obtained by the winning party does not diminish throughout the many years between the breach and enforcement of the award. Despite its importance, interest is often the last element considered by arbitration practitioners, who sometimes rely on popular interest rate benchmarks that worked well in the past. However, some familiar benchmarks might no longer achieve the intended outcome.
We have reviewed public investment arbitration awards rendered in 2019–2020 and identified three issues: the use of LIBOR despite its imminent phase-out, the use of benchmarks that have become negative, and the omission of interest from awards rendered in favour of respondent states. While solutions may vary, we discuss mechanisms that may be used to review existing awards, alternative interest rate benchmarks that may replace LIBOR, and floors that might be helpful to deal with negative interest rates.
Arbitration practitioners regret to see it when transactional lawyers negotiate arbitration clauses as ‘midnight clauses’. However, it often escapes the arbitration community that it adopts a similar last minute approach to interest rates. It is hoped that this article might help interest rates avoid the fate of being a ‘midnight remedy’.
A new hybrid stent using endoscopic vacuum therapy in treating esophageal leaks: a prospective single-center experience of its safety and feasibility with mid-term follow-up
Authors: Chon Seung-Hun , Scherdel Julia , Rieck Isabel , Lorenz Florian , Dratsch Thomas , Kleinert Robert , Gebauer Florian , Fuchs Hans Friedrich , Goeser Tobias , Bruns Christiane Josephine 
Published: September 2021

Summary
Self-expandable metal stents (SEMS) and endoscopic vacuum therapy (EVT) are endoscopic options for treating leaks of the esophagus. VACStent® is a variant of SEMS that aims to combine the advantages of SEMS and EVT in one device. Due to this unique construction, VACStent® can build a barrier to the leak and facilitate wound healing with EVT, all while maintaining intestinal passage. We present the first prospective feasibility study of VACStent® for treating leaks of the upper gastrointestinal tract. Between September 2019 and November 2020, we performed a prospective, investigator-initiated, single-center study and included all patients who underwent endoscopic stenting with VACStent® for various kinds of esophageal leaks, such as spontaneous, iatrogenic or anastomotic leaks. We included 20 patients, who underwent a total of 24 endoscopic VACStent® implantations. Technical success of the application of the VACStent® was achieved in all interventions (n = 24, 100%). Overall, clinical success in closing the leaks with VACStent® treatment was achieved in 60% of patients (12/20). No severe VACStent® treatment-related adverse events occurred. Oral feeding with supplement high-energy drinks failed in all patients due to clogging of the suction tube. VACStent® is a safe and feasible endoscopic treatment option for leaks of the upper gastrointestinal tract. However, our data could not show the expected advantage of orally feeding the patients during the treatment with the VACStent® in its current form. Efficacy of VACStent® compared to EVT or SEMS needs to be investigated in a further study. ClinicalTrials.gov Identifier: NCT03962179.
The STRIPAK component SipC is involved in morphology and cell-fate determination in the nematode-trapping fungus Duddingtonia flagrans
Authors: Wernet Valentin , Wäckerle Jan , Fischer Reinhard 
Published: September 2021

Abstract
The striatin-interacting phosphatase and kinase (STRIPAK) complex is a highly conserved eukaryotic signaling hub involved in the regulation of many cellular processes. In filamentous fungi, STRIPAK controls multicellular development, hyphal fusion, septation, and pathogenicity. In this study, we analyzed the role of the STRIPAK complex in the nematode-trapping fungus Duddingtonia flagrans which forms three-dimensional, adhesive trapping networks to capture Caenorhabditis elegans. Trap networks consist of several hyphal loops which are morphologically and functionally different from vegetative hyphae. We show that lack of the STRIPAK component SipC (STRIP1/2/HAM-2/PRO22) results in incomplete loop formation and column-like trap structures with elongated compartments. The misshapen or incomplete traps lost their trap identity and continued growth as vegetative hyphae. The same effect was observed in the presence of the actin cytoskeleton drug cytochalasin A. These results could suggest a link between actin and STRIPAK complex functions.
Age Patterns in Self-Reported Cognitive Impairment Among Older Latino Subgroups and Non-Latino Whites in the United States, 1997–2018: Implications for Public Health Policy
Authors: Garcia Marc A , Warner David F , García Catherine , Downer Brian , Raji Mukaila 
Published: September 2021

Abstract

Background and Objectives
U.S. Latinos are a heterogeneous population with unique characteristics related to individual-level socioeconomic and contextual factors based on nativity status and country of origin. Population aging and greater public awareness of dementia may contribute to an increasing prevalence of self-reported cognitive impairment. However, population-level trends in self-reported cognitive impairment among Latinos are unclear and it is unknown whether there are differences among Latino subgroups. Thus, this study aims to examine heterogeneity in self-reported cognitive impairment among older U.S. Latino subgroups.

Research Design and Methods
We used data from the 1997–2018 National Health Interview Survey to document age-specific patterns in self-reported cognitive impairment among U.S.-born Mexican, foreign-born Mexican, island-born Puerto Rican, foreign-born Cuban, and U.S.-born non-Latino Whites aged 60 and older. We estimated hierarchical age–period–cohort cross-classified random effects models (HAPC-CCREM) to isolate age patterns in self-reported cognitive impairment across disaggregated Latino subgroups and U.S.-born non-Latino Whites.

Results
The overall prevalence of self-reported cognitive impairment increased from 6.0% in 1997 to 7.1% in 2018. This increase was evident among U.S.-born non-Latino Whites and U.S.-born and foreign-born Mexicans but not other Latino subgroups. Fully adjusted HAPC-CCREM estimates indicated that Latinos were more likely to self-report cognitive impairment than U.S-born non-Latino Whites (b = 0.371, p &lt; .001). When disaggregated by Latino subgroup, the difference in the likelihood for self-reported cognitive impairment compared to U.S.-born non-Latino Whites was greatest for island-born Puerto Ricans (b = 0.598, p &lt; .001) and smallest for foreign-born Cubans (b = 0.131, p &gt; .05).

Discussion and Implications
We found evidence of considerable heterogeneity in the age patterns of self-reported cognitive impairment among U.S. Latino subgroups. We also detected large differences in the likelihood for self-reported cognitive impairment between U.S. Latino subgroups compared to U.S.-born non-Latino Whites. These results underscore the importance of differentiating between unique Latino subpopulations when studying population-level trends in cognitive function.
Settler Military Politics: On the Inclusion and Recognition of Indigenous People in the Military
Authors: Caso Federica 
Published: September 2021

Abstract
After decades of refusal, neglect, and tacit admittance, the service of Indigenous people in the national armed forces of settler colonial states such as Australia, Canada, New Zealand, and the United States is finally gaining acknowledgment. Indigenous people are now integrated in the regular forces and represented in national war commemoration. This article maintains that while inclusion and recognition of Indigenous military service is a positive transformation in the direction of post-colonial reconciliation, it still operates within the logics of settler colonialism intended to eradicate Indigenous stories of connection to land and assimilate Indigenous people in settler society. Using the case study of Indigenous militarization in Australia, this article argues that, under conditions of settler colonialism, the inclusion and recognition of Indigenous people in national militaries advances the settler colonial project intended to dispossess Indigenous people from their land and assimilate them in the new settler society. It highlights that historically, military organization has supported settler colonialism, and positions the present inclusion and recognition of Indigenous people in the military as a continuation of this history.
Efficacy of tantalum rod insertion for preventing femoral head collapse in osteonecrosis in a paediatric population: a pilot study
Authors: Hussaini Muqtasid , Balakumar Jitendra , Slattery David 
Published: September 2021

ABSTRACT
Femoral head osteonecrosis in the paediatric population is difficult to treat, with the primary goals of management being prevention of subchondral collapse and the avoidance of early total hip replacement. This study aims to describe the use of a porous tantalum rod implant to provide mechanical support in preventing femoral head collapse in a paediatric population. A retrospective chart-based analysis of patients with osteonecrosis of the hip was performed at our institution to identify those who had undergone tantalum rod insertion. A total of 10 patients (fives males and five females, median age 12.5 years, 9–18) had tantalum rods implanted between December 2013 and February 2018. One patient was excluded due to follow-up at a different institution. The radiographic degree of osteonecrosis was characterized according to the Ficat classification and the Kerboul angle. Radiographic assessment of pre- and post-operative plain films was performed. The outcome measures were Tonnis grade and percentage collapse of the femoral head. Nine patients with a mean follow-up time of 18.4 months were included in the analysis. There was no significant increase in the femoral head collapse percentage post tantalum rod insertion compared to pre-operatively (P = 0.63). There was a significant increase in the Tonnis grade post-operatively (P &lt; 0.05), with sub-group analysis showing minimal increase in Ficat Stage 1 patients. This study is the first to examine the role of tantalum rod insertion in preventing femoral head collapse in a paediatric population, with results suggesting potential benefit in a subset of patients.
Development of an adaptive explicit algorithm for static simulation using the vector form intrinsic finite element method
Authors: Wang Mien-Li , Chuang Ching-Chiang , Lee Jyh-Jone 
Published: September 2021

Abstract
The vector form intrinsic finite element (VFIFE) method is a solution technique for nonlinear structural problems, which describes a continuous body using a set of particles instead of a mathematical function. Thus, a dynamic particle equation can be established by Newton's law of motion, and a viscous or kinetic damping can be introduced to obtain the steady state of the structure. This paper focuses mainly on the development of a stability condition regarding the explicit central difference method used in VFIFE to guarantee the system's convergence. The process is established and evaluated in combination with a dynamic relaxation method with kinetic damping and discrete control theory. Four numerical examples of structure nonlinear problems are used to verify the accuracy, stability and efficiency of the method.
On the thermal instability of supercavitating liquid jet surrounded by coaxial rotary gas
Authors: Lü Ming , Ning Zhi 
Published: September 2021

Abstract
Based on the jet stability theory, under the conditions of gas rotation, fluid compressibility and supercavitation, this paper gives the mathematical model describing the thermal instability of supercavitating liquid jet surrounded by a coaxial rotary gas, and the corresponding numerical method for solving the mathematical model is proposed and verified by the data in reference. Then, this paper analyzes the effects of gas–liquid temperature differences and temperature gradients on jet instability, and studies the thermal stability of supercavitating jet. The results show that the maximum disturbance growth rate, the dominant frequency and the maximum disturbance wave numbers increase linearly with the increase of gas–liquid temperature differences. The existence of temperature gradient inside the jet makes the effects of temperature differences on jet instability more obvious. The temperature gradient will inhibit the effect of supercavitation on jet instability, while gas–liquid temperature difference will promote the effect of supercavitation on jet instability.
Long-term use of glucocorticoid exacerbates bone lesions in postmenopausal women with rheumatoid arthritis
Authors: Hatano Masaki , Kitajima Izuru , Nakamura Masaki , Isawa Kazuya , Suwabe Tatsuya , Hoshino Junichi , Kinowaki Keiichi , Ohashi Kenichi , Sawa Naoki , Yamamoto Seizo , Ubara Yoshifumi 
Published: September 2021

ABSTRACT
Glucocorticoid-induced osteoporosis is osteoporosis arising due to long-term use of glucocorticoids. Despite decades of intense research, the effects of long-term use of glucocorticoids in humans on bone cells and bone structural changes remain unclear. We performed post-mortem histomorphometric analysis of bone from two female patients with rheumatoid arthritis aged 64 and 85 years. Our two patients had been treated with glucocorticoids for 19 and 14 years, respectively. In Case 1, all markers of cancellous bone volume were markedly decreased compared with the age-matched reference range. Connectivity of cancellous bone trabecula was absent. Only a few island bones were noted. There was prominent thinning of the cortical bone and extension of the bone marrow cavity into the cortical bone with prominent cortical porosis. Cortical nodes between the endocortical surface and the trabecula disappeared due to endocortical resorption. Stoppage of lamellar structure was observed because the bone resorption by osteoclasts surpassed bone formation by osteoblasts. Empty lacunae characterised by disappearance of osteocytes were visible. In Case 2, all volume markers of cancellous bone were decreased to the same extent as Case 1. However, cortical porosis was more prominent than Case 1. These two cases suggest that use of glucocorticoid therapy &gt;10 years can induce severe osteoporosis in elderly rheumatoid arthritis women with higher disease activity and that the disappearance of cancellous bone is the common characteristic. The 85-year-old woman was characterised by cortical porosis.
X-linked hypophosphataemic rickets: Report of a novel PHEX mutation and cinacalcet as adjuvant therapy in the mineral metabolism control
Authors: Cavaco Daniela , Amaro Pedro , Simões-Pereira Joana , Pereira Maria Conceição 
Published: September 2021

ABSTRACT
X-linked hypophosphataemic rickets (XLH) is a rare disease caused by a mutation in the phosphate-regulating neutral endopeptidase (PHEX) gene, located on the X chromosome. This gene encodes the phosphate-regulating endopeptidase, and its inactivation leads to increased levels of circulating phosphatonins responsible for renal phosphate loss. The treatment for XLH is still carried out with long-term administration of phosphate and calcitriol, which can be complicated by hyperparathyroidism, nephrocalcinosis, renal failure, and hypertension. We describe the case of a four-decade follow-up patient with XLH. When she was diagnosed, at 19 years, due to bone pain and deformities, she was put on therapy with phosphorus and cholecalciferol. Despite the clinical improvement, serum phosphorus remained difficult to control. At the age of 44 years, she developed tertiary hyperparathyroidism and was submitted to parathyroidectomy. Five years later, parathyroid hyperfunction recurred. This time, cinacalcet was started, 30 mg alternating with 60 mg/day. Currently, she is 59-years old and remains with controlled mineral metabolism. The genetic study of this patient revealed a nonsense heterozygous mutation (c.501G&gt;A) in PHEX gene that was not previously described. In this case, the off-label use of cinacalcet resulted in the normalisation of serum parathormone and phosphorus levels, eliminated recurrent secondary hyperparathyroidism, which aggravates the bone fragility inherent to XLH, and prevented a new parathyroidectomy. This report also adds important information to the genetic basis of XLH with the identification of a new nonsense mutation of the PHEX gene.
Association Between Hemagglutination Inhibition Antibody Titers and Protection Against Reverse-Transcription Polymerase Chain Reaction–Confirmed Influenza Illness in Children 6–35 Months of Age: Statistical Evaluation of a Correlate of Protection
Authors: Danier Jasur , Callegaro Andrea , Soni Jyoti , Carmona Alfoso , Kosalaraska Pope , Rivera Luis , Friel Damien , Pu Wenji , Vantomme Valerie , Dbaibo Ghassan , Innis Bruce L , Schuind Anne , Zaman Khalequ , Wilson Jerome 
Published: September 2021

Abstract

Background
Data from a randomized controlled efficacy trial of an inactivated quadrivalent influenza vaccine in children 6–35 months of age were used to determine whether hemagglutination inhibition (HI) antibody titer against A/H1N1 and A/H3N2 is a statistical correlate of protection (CoP) for the risk of reverse-transcription polymerase chain reaction (RT-PCR)–confirmed influenza associated with the corresponding strain.

Methods
The Prentice criteria were used to statistically validate strain-specific HI antibody titer as a CoP. The probability of protection was identified using the Dunning model corresponding to a prespecified probability of protection at an individual level. The group-level protective threshold was identified using the Siber approach, leading to unbiased predicted vaccine efficacy (VE). A case-cohort subsample was used for this exploratory analysis.

Results
Prentice criteria confirmed that HI titer is a statistical CoP for RT-PCR–confirmed influenza. The Dunning model predicted a probability of protection of 49.7% against A/H1N1 influenza and 54.7% against A/H3N2 influenza at an HI antibody titer of 1:40 for the corresponding strain. Higher titers of 1:320 were associated with &gt;80% probability of protection. The Siber method predicted VE of 61.0% at a threshold of 1:80 for A/H1N1 and 46.6% at 1:113 for A/H3N2.

Conclusions
The study validated HI antibody titer as a statistical CoP, by demonstrating that HI titer is correlated with clinical protection against RT-PCR–confirmed influenza associated with the corresponding influenza strain and is predictive of VE in children 6–35 months of age.

Clinical Trials Registration
NCT01439360.
Community Airborne Mold Spore Counts and Invasive Fungal Disease Risk Among Pediatric Hematological Malignancy and Stem Cell Transplant Patients
Authors: Almatrafi Mohammed A , Aquino Victor M , Slone Tamra , Huang Rong , Sebert Michael 
Published: September 2021

Abstract

Background
Patients with hematological malignancies and hematopoietic stem cell transplantation (HSCT) recipients are at risk of developing invasive fungal infections, but the quantitative risk posed by exposure to airborne mold spores in the community has not been well characterized.

Methods
A single-institution, retrospective cohort study was conducted of pediatric patients treated for hematological malignancies and HSCT recipients between 2014 and 2018. Patients with invasive fungal disease (IFD) due to molds or endemic fungi were identified using published case definitions. Daily airborne mold spore counts were obtained from a local National Allergy Bureau monitoring station and tested for association with IFD cases by 0-inflated Poisson regression. Patients residing outside the region or with symptom onset more than 2 weeks after admission were excluded from the primary analysis.

Results
Sixty cases of proven or probable IFD were identified, of whom 47 cases had symptom onset within 2 weeks of admission and were therefore classified as possible ambulatory onset. The incidence of ambulatory-onset IFD was 1.2 cases per 10000 patient-days (95% CI, 0.9–1.7). A small excess of ambulatory-onset IFD was seen from July through September, during which period spore counts were highest, but this seasonal pattern did not reach statistical significance (P = .09). No significant association was found between IFD cases and community mold spore counts over intervals from 1 to 6 weeks before symptom onset.

Conclusions
There was no significant association between IFD cases and community airborne mold spore counts among pediatric hematological malignancy and HSCT patients in this region.
Evaluating and Optimizing Dentato-Rubro-Thalamic-Tract Deterministic Tractography in Deep Brain Stimulation for Essential Tremor
Authors: Bot Maarten , van Rootselaari Anne-Fleur , Odekerken Vincent , Dijk Joke , de Bie Rob M A , Beudel Martijn , van den Munckhof Pepijn , Schuurman P Richard 
Published: September 2021

Abstract

BACKGROUND
Dentato-rubro-thalamic tract (DRT) deep brain stimulation (DBS) suppresses tremor in essential tremor (ET) patients. However, DRT depiction through tractography can vary depending on the included brain regions. Moreover, it is unclear which section of the DRT is optimal for DBS.

OBJECTIVE
To evaluate deterministic DRT tractography and tremor control in DBS for ET.

METHODS
After DBS surgery, DRT tractography was conducted in 37 trajectories (20 ET patients). Per trajectory, 5 different DRT depictions with various regions of interest (ROI) were constructed. Comparison resulted in a DRT depiction with highest correspondence to intraoperative tremor control. This DRT depiction was subsequently used for evaluation of short-term postoperative adverse and beneficial effects.

RESULTS
Postoperative optimized DRT tractography employing the ROI motor cortex, posterior subthalamic area (PSA), and ipsilateral superior cerebellar peduncle and dentate nucleus best corresponded with intraoperative trajectories (92%) and active DBS contacts (93%) showing optimal tremor control. DRT tractography employing a red nucleus or ventral intermediate nucleus of the thalamus (VIM) ROI often resulted in a more medial course. Optimal stimulation was located in the section between VIM and PSA.

CONCLUSION
This optimized deterministic DRT tractography strongly correlates with optimal tremor control. This technique is readily implementable for prospective evaluation in DBS target planning for ET.