bluuebunny/crossref_metadata_2025_split huggingface dataset:
Severity and immediate neurodevelopmental outcome in term neonates with hypoxic-ischemic encephalopathy admitted in NICU at a tertiary hospital in Bangladesh
Authors: Debnath Bithi , Khan Naila Zaman , Mahfuz Rumana , Mollah Abid Hossain 
Published: April 2021

Background: Neonatal hypoxic ischemic encephalopathy (HIE) is a major cause of mortality, morbidity and long-term neurological deficits.
Objective: The aim of the study was to determine the severity of encephalopathy and immediate neurodevelopmental outcomes in term neonates with HIE admitted in NICU at a tertiary care hospital.
Materials and Methods: This was a Prospective Cohort study conducted between July 2016 and June 2017 at Dhaka Medical college Hospital, Dhaka. Asphyxiated term newborns who came within 12 hours of birth were enrolled in this study. Sarnat and Sarnat score was used to assess newborns immediately after birth to classify HIE. Neurodevelopmental assessment was performed using age specific rapid neurodevelopmental assessment tool (RNDA) at and 3 months after discharge to identify impairment in specific developmental domains. We determined the relation between severity of HIE and clinical outcome.
Results: 60 patients were included in this study and their mean duration of hospital stay was 7.19 ± 5.26 days. The majority, 40% had moderate HIE, followed by 33.33%, 26.67% that had mild and severe HIE respectively. A total of 20% died, and most of them had severe HIE (83.33%). Normal development was found in only 11.67% cases. Moderate and severe neurodevelopmental impairment (NDI) was found in 33.33% and 25% cases respectively. At discharge, the most severely impaired domains were speech, seizure, primitive reflex and behaviour whereas at 3 months of age it was gross motor and seizure. When neurodevelopmental outcome was compared with different stages of encephalopathy, significant association was found between moderate to severe impairment/death with stage III of HIE.
Conclusion: Apart from mortality, a significant proportion of term neonates with HIE developed NDIs and adverse neurodevelopmental outcomes was significantly associated with severity of encephalopathy.
Bangladesh Crit Care J March 2021; 9(1): 22-27
Potential long term adverse health outcomes of COVID-19
Authors: Siddiqua Dibanur Rashid , Hossain Md Shahadat 
Published: April 2021

The coronavirus disease 2019(COVID-19) pandemic poses an extraordinary challenges to patients, communities and overall health care systems. It has resulted in millions of people infected worldwide and has indirectly devastated even more individuals with prolonged post-infectious symptoms. The burden of survivors having post-COVID symptoms is likely to be huge. Multidisciplinary post-COVID-19 clinics are now playing a pivotal role addressing both persistent symptoms and potential long term sequelae. In this review, we tried to summarize the adverse health outcomes based on current evidences, assess the potential risk of long-term complications and make certain recommendations.
Bangladesh Crit Care J March 2021; 9(1): 38-40
Laparoscopic Cholecystectomy in a patient with Situs Inversus Totalis
Authors: Shahjahan Samail , Rahman Anisur 
Published: April 2021

There are diagnostic and therapeutic challenges in cases of symptomatic gall bladder disease in patients with situs inversus totalis (SIT), where there is complete reversal of visceral topography in thorax, abdomen or both. The difficulty to treat these patients with conventional laparoscopic cholecystectomy may be more pronounced for right handed surgeon and requires modifications in working ports and their positions. We present a case of laparoscopic cholecystectomy in a patient with SIT, and describe the technical details that enable the safe conclusion of the operation.
Bangladesh Crit Care J March 2021; 9(1): 43-45
Tissue plasminogen activator (tPA) treatment for COVID_19 associated acute respiratory distress syndrome (ARDS): A case report
Authors: Hoque Muhammad Mazharul , Islam Motiul , Hamid Tarikul , Halim Rabiul , Hasan Rajib , Ahmed Kazi Nuruddin 
Published: April 2021

Coagulopathy has proven to be a common complication of the novel coronavirus SARS-CoV-21. Some of the COVID-19 associated pneumonia patients exhibit relatively preserved lung compliance and high alveolar‐arterial oxygen gradient. Pathology reports consistently demonstrate diffuse pulmonary microthrombi on autopsy, consistent with a vascular occlusive etiology of respiratory failure rather than the more classic findings of ARDS2. Pulmonary microthrombi induced respiratory failure is very difficult to prove because the patients are so critically ill that transfer to CT suit to do CTPA often becomes unsafe for the patients. Moreover, performing V/Q scan is increasingly difficult in such settings. Here we report a case of severe COVID-19 associated respiratory failure who was treated with tissue plasminogen activator (tPA) on clinical ground.
Bangladesh Crit Care J March 2021; 9(1): 49-51
COVID-19 presenting with Ophthalmoplegia in a patient with Acute Kidney Injury
Authors: Gomes Pauline Francisca , Momen Abdul Basit Ibne , Sultana Amrin , Alam Rafa Faaria , Saber Sadia , Alam Mohammed Tarek 
Published: April 2021

COVID-19 has proved to cause multi-systemic manifestations in many reported cases across the world. Here, we report a rare presentation of a 20 years old COVID-19 positive male patient with acute kidney injury who developed ophthalmoplegia during the course of the disease. COVID-19 being a relatively new disease, its neurological manifestation is even rarer with limited literature concerning the symptoms. Clinicians should, therefore, have a high suspicion and awareness regarding the many faces of the severe acute respiratory syndrome coronavirus-2(SARS-CoV-2), for early detection and mitigation of the disease, especially during the pandemic.
Bangladesh Crit Care J March 2021; 9(1): 59-61
Post COVID Cardiovascular Care - A Review
Authors: Mohammad Ullah - , Islam AKM Monwarul , Akanda Md Abdul Kader , Majumder Abdullah Al Shafi 
Published: April 2021

Over the last one-year COVID 19 has affected millions of people around the world. Though initially it was thought to be an infection of respiratory system, but it involves any organ of the body. Its morbidity and mortality are more when it involves patients with preexisting cardiovascular diseases and also when it causes a cardiovascular complication. COVID 19 can produce a number of cardiovascular complications including myocardial infarction, heart failure, myocarditis, arrhythmia, thromboembolism etc. Following recovery from COVID 19 infection evaluation, follow up and management of these cardiovascular conditions, which may be sometimes in subclinical form, is essential. Though there is lack of adequate studies or guidelines, we tried to discuss the different aspects of Post- COVID cardiovascular care depending on the existing evidence and previous guidelines.
Cardiovasc. j. 2021; 13(2): 189-199
Ischemia of Non-Obstructive Coronary Artery Disease: Need to Address in our Patient Population
Authors: Islam AHM Waliul , Reza AQM , Munwar Shams , Talukder Shahabuddin , Ahmed Tamzeed , Rahman Kazi Atikur , Ali Md Atahar 
Published: April 2021

Ischemia of non-occlusive coronary artery disease (INOCA) not an uncommon phenomenon, exist in our patient population which did not address well. Many of the stable angina and or unstable angina patient, whose coronary angiogram revealed significant coronary stenosis (>70%) are being treated by PCI with drug eluting stent. On the contrary, quite a significant proportion of patient, who are found to have non-significant coronary lesion (<50%) or essentially normal epicardial coronaries. These group of patients with angiographic evidence of non-occlusive CAD, remain undiagnosed of their exact etiology of angina. As a result, recurrence of anginal chest pain leading to repeat hospitalization impaired quality of life and the expenditure. Women are significant number in this category, labelled as syndrome X. Many of the scientific literature, has labeled it as Ischemia of Non obstructive Coronary artery Disease. Notably, Microvascular angina is due to ischemia driven mismatch of demand and supply in the myocardium. Microvascular Dysfunction (MVD) and Coronary vascular spasm or Vasospastic Angina (VSA) are the main pathogenic causes of INOCA. With the advent of Imaging physiology, and its availability in Bangladesh, many of the center can assess INOCA and its severity by FFR, iFR, DFR and transthoracic Doppler study of the coronaries. Therefore, we recommend evaluating INOCA patient by available technical assistance and to address the issue and patients suffering with repeated hospitalization and financial expenditure.
Cardiovasc. j. 2021; 13(2): 217-222
Comfort and safety for the oncological client with indication of central venous catheter use: The intentionality of nurses
Authors: Cunha Maria Amália de Lima Cury , Rosas Ann Mary Machado Tinoco Feitosa , Rodrigues Benedita Maria Rêgo Deusdará , Araujo Cláudia Regina Gomes de , Azevedo Suely Lopes de , Oliveira Aline Silva da Fonte Santa Rosa de , Santiago Adriana da Silva , Pereira Sinara Santos , Vasconcelos Suzy Darlen Dutra de 
Published: April 2021

Objective: To understand the expectations of the educational actions of 41 nurses in the nursing consultation for oncologic clients when they indicate a central venous catheter (CVC) for treatment. Method: Phenomenological qualitative research with 41 nurses indicating the use of CVC for treatment in oncologic clients of two units of a federal public hospital institution located in the city of Rio de Janeiro and specialized in oncology. Semi-structured interviews were used and the data were analyzed according to Alfred Schütz's conceptions. Results: It was possible to identify the following categories: promoting comfort and safety for both the client and the professional; demystifying the use of the central venous catheter for the client; obtaining the client's collaboration. Conclusion: The findings of the study revealed that the nurses aim to promote comfort and safety for the oncologic client throughout the treatment to prevent complications, even in cases where there is no prospect of cure. These professionals aim to sensitize the client to a possible change in behavior and that should be shared among the professionals of the multidisciplinary team of an interdisciplinary knowledge, the client, the family member in the search for the quality of appropriate and unique treatment.
Cytotoxicity in fibroblasts from young and elderly donors from two mouthwashes used to prevent the spread of SARS-CoV-2
Authors: Tavares Sandro J. de Oliveira , Caldas Isleine Portal , Gonçalves Fabiano Palmeira , Scelza Pantaleo , Oliveira Felipe , Alves Gutemberg , Scelza Miriam F. Zaccaro 
Published: April 2021

In cases of injuries in the oral cavity, the mouthwash comes in contact with the underlying gingival connective tissue and should have its cytotoxicity assessed. However, there is no available evidence if cells of elderly donors react differently during in vitro assessments of mouthwashes. This study aimed to compare the cytotoxicity evaluation of two different mouthwash types when assessed with primary gingival fibroblasts from either young and older donors. Primary cells were collected from two elderly patients (mean age 66.5 years old) and two young patients (mean age 27.5 years old). The primary cell culture was produced from gingival fragments and exposed for 24h in Perioxidin® and Oral B®. A control group was exposed to unconditioned culture media, representing 100% of cell survival (negative control), and 200mg/mL solution of latex fragments was used as a positive control due to its well-known toxicity. Both products presented similar dose-dependent cytotoxicity. In the toxic range, from 0.035% to 0.00035% for Perioxidin® and 0.06 to 0.0006% for Oral B®. The calculated IC50 values were very similar, with the exception of Oral B® tested with young cells, which presented a slightly higher toxic concentration (0.0523 mM). The statistical analysis shows no significant difference between tests with cells from young our elderly donors (p >0.05). These mouthwashes should should be used sparingly to prevent the spread of SARS-CoV-2. However, the use of age-matched cells during in vitro tests may not be necessary to predict differences in the biological response of the elderly to these products.
Antibacterial effectiveness of drug combinations with calcium hydroxide in apical periodontitis: A systematic review
Authors: Velozo Christianne , Lemos Cleidiel Aparecido Araújo , Albuquerque Diana Santana de , Vasconcelos Belmiro Cavalcante do Egito , Moraes Sandra Lúcia Dantas , Pellizzer Eduardo Piza 
Published: April 2021

The aim of this systematic review was to compare the clinical performance of calcium hydroxide (Ca(OH)2) as an intracanal medicament alone or combined with other antimicrobial agents. The PICO question was “Is the antibacterial effectiveness of calcium hydroxide paste as an intracanal medication combined with other drugs greater than that of calcium hydroxide paste alone in apical periodontitis?” The study was carried out according PRISMA guidelines and is registered in PROSPERO (CRD42020205741). Searches were performed in the PubMed/MEDLINE, Web of Science and Cochrane databases without publication date restrictions. Inclusion: randomized clinical trials, non-randomized intervention studies, studies including a minimum of 10 patients, studies comparing the use of Ca(OH)2 alone and in combination with other compounds, studies evaluating primary and permanent teeth with apical periodontitis, and studies including teeth not submitted to retreatment. The Cochrane risk-of-bias tool for randomized clinical trials (RoB 2.0) was used to assess the internal validity (risk of bias) of the included studies. A total of 986 articles were retrieved and 12 randomized clinical trials were selected, totaling 499 patients included in the studies. The effectiveness of Ca(OH)2 plus chlorhexidine was similar to that of Ca(OH)2 alone in eight articles, while a better antibacterial effect was reported in three studies. The combination with ciprofloxacin was more effective than the use of Ca(OH)2 alone in the only study that tested this antibiotic. In teeth with asymptomatic apical periodontitis, the effectiveness of the combination of antimicrobial agents with Ca(OH)2 was similar to that of Ca(OH)2 alone.
Assessment of women’s economic empowerment in the rice cultivation sector of the upper Punjab region, Pakistan
Authors: Akhtar Saira , Ahmad Shabbir , Huifang Wu , Imran Shakeel , Wang Chunyu , Hassan Gulfam , Tabasam Nazia , Mahmood Khalid 
Published: April 2021

The present study was conducted to identify and discuss the social norms, perceptions, and expectations which shape or constraint men’s, and women’s economic empowerment. The current study was conducted in the rice cultivation sectors of Sheikhupura and Gujranwala districts of the Punjab Province, Pakistan. A qualitative (cross-sectional) study was designed to get responses from the respondents of the targeted area. One tehsil was purposively selected from each district and sixty-five respondents (both males and females) were invited from 13 different villages of the above-mentioned tehsils. Focused Group Discussions (FGDs) were held for data collection activity in collaboration with the Doaba Foundation. A pre-defined interview guide based on Oxfam’s Social Norms Diagnostic Toolkit and Rapid Care Analysis Toolkit was used to collect opinions from the respondents with the inclusion of various exercises. The major findings of the study revealed that most of the care work yielded by women ranging from the rice cultivation to the household chores go unacknowledged, because it is included in the total household income, and the rural women face discrimination in every sphere of life. The study concludes that to achieve women’s economic empowerment, adequate wages, and safe working conditions, where they are protected from sexual and gender-based violence, must be ensured. The government should devise policies for the protection of women regarding discrimination and implement it in true spirit to fulfil the dream of the economic empowerment of women in Pakistan.
Awareness, Attitudes, and Infection Control Measures of Dentists in Turkey Regarding COVID-19 Pandemic
Authors: GÜNAL Burcu , ABDULJALİL Mohamad , TUNASOYLU Begüm 
Published: April 2021

Objective: Corona virus disease is a serious acute respiratory infection that has spread worldwide. The aim of this survey study was to evaluate the knowledge levels, attitudes, and approaches of dentists in Turkey and to investigate the infection control measures applied by the dentists in the dental clinics regarding the COVID-19 pandemic.
Methods: This survey consisted of 27 questions and was conducted in May 2020. The questionnaire, which was distributed online to the participants through their personal accounts, included questions about the socio-demographic characteristics of the participants, their knowledge and awareness of COVID-19 infection, their approach to dental procedures before and during the pandemic, and the control measures they took in dental clinics. The collected data were subjected to statistical analysis using Chi-square tests and P values of < 0.05 were accepted as statistically significant.
Results: Eight hundred twenty-eight dentists completed the questionnaire forming a response rate of 51.8%. The majority of the participants demonstrated a high level of knowledge and awareness regarding COVID-19. The statistical analysis showed that there was no association between the gender of dentists and the applied infection control measures (P > 0.05), while there were significant associations between the health sectors and experience years with the infection control measures (P < 0.05).
Conclusion: These results demonstrated an adequate level of knowledge regarding COVID-19 among dentists in Turkey. Additionally, the rate of using personal protective equipment during dental treatment was high.
THE MYTHOMODEL OF THE UNIVERSE IN THE INTERPRETATION OF P. KULISH (STORY «FIRE SNAKE»)
Authors: MATVIEIEVA T. 
Published: April 2021

The paper is devoted to insufficiently investigated subject of modern Ukrainian literary criticism – the novelette by P. Kulisha «Fire snake». The purpose of the paper is to outline the features of the world, modeler by the author, using the three-tier structural division of reality scheme tested in the literature.The main attention was focused on the study of the peculiarities of the functioning of the mechanism of simultaneous interaction and reciprocation of the levels of the world model. The following techniques have been identified – gradation, oxymoron, antinomy, mirroring, etc., by them the author builds each of the simulated spaces, namely: the upper world – the heaven as the abode of God; median space – antroposphere; the lover world is the chaos of unholy power.A separate aspect of interests is the specificity of the presentation of the through character of the story – gold – as a dual phenomenon that accumulates binary meanings. Also, it was about folk and philosophical semantics of the meaning – and structure-forming image of the story – a fire snake – the materialized embodiment of the temptation and the sin.The basic means of creation of characters are analysed: the author’s characteristic, the use of a doubleimage. The semantics of irrational is in the sphere of interest of the author of the paper as well.It was proved that modeled by P. Kulish world is incomplete, deformed by an incorrect understanding of its own existence. In fact, this is a model, the basis of which is the paradox: the man essence ruined by the vanity of humanity destroys the antroposphere, shifts the world axis down into the world of chaos, eventually dehumanizing its own perspective, restructuring the universe on the principle of absolute character of pre-term.
Investigation Of The Relationship Between Pelvic Ring Pain And Interpubic Distance
Authors: TERZİ Elif , KAYA Özgür 
Published: April 2021

ABSTRACT
Aims: To show that USG, which is used in routine pregnancy examination, can be useful in the diagnosis of pelvic ring pain.
Methods: In our study, the interpubic distance width was measured with USG in 287 patients who had routine pregnancy control in addition to their normal examinations. Necessary clinical tests were performed by orthopedics and traumatology specialist in order to clarify the diagnosis of pelvic ring pain. The results were noted and IBM SPSS Statistics 20 program was used for evaluations and p
Gallbladder condition in patients with rheumatic fever and acquired valve defects of rheumatic origin
Authors: Strilchuk L. M. , Yatsev Yu. М. 
Published: April 2021

Gallbladder (GB) and heart are linked by viscero-visceral reflexes, but little is known about the connections between GB and heart in patients with acute and chronic rheumatic heart disease.
Purpose of the study. To assess the GB condition in patients with acute and chronic rheumatic disease and the difference in structural and functional sonographic parameters of heart in dependence of GB condition.
Materials and methods. We examined 136 patients including 58 patients with active rheumatism (mean age 36,72 ± 3,00 years), 44 patients with chronic rheumatic heart disease (CRHD), who underwent surgical correction of the valvular defect (mean age 54,00 ± 3,69 years), and 34 patients with CHD, who were treated as inpatients withour surgery (mean age 61,48 ± 4,50 years).
Results. Among 136 patients with acute and chronic forms of rheumatic heart disease, GB changes were significantly more common than intact GB (62,5 ± 4,1% vs. 37,5 ± 4,1%, p < 0,05). The incidence of GB disorders was the highest in patients with CRHD, who underwent drug treatment (76,5 ± 7,3% vs. 58,7 ± 6,5% and 50,0 ± 7,5%, both p < 0,05), which were characterized by older age. No significant differences in the incidence of various pathological conditions of GB were revealed between acute and chronic rheumatic heart disease groups. The most common pathological GB changes included signs of cholecystitis, biliary sludge and cholesterosis, cholelithiasis, the least common – GB removal due to cholelithiasis. Patients with biliary autonomic viscero-visceral cardioneuropathy differed from those with intact GB by the thickening of the interventricular septum and posterior wall of the left ventricle, which correlated with the increased duration of inpatient treatment, diastolic hypertension and lower alanine aminotransferase.
Conclusions. In patients with acute and chronic forms of rheumatic heart disease, the GB condition is often changed. These changes affect heart condition, blood pressure and carbohydrate metabolism.