bluuebunny/crossref_metadata_2025_split huggingface dataset:
A rare case of intestinal obstruction in pregnancy
Authors: Sharma Karishma , Saxena Somya , Agnihotri Rahul 
Published: August 2021

Intestinal obstruction (IO) in pregnancy is rare at 1 in 2500 to 1 in 16709 deliveries with an incidence of 0.001% to 0.003%. Although uncommon, IO in pregnancy carries significant maternal (6%) and fetal (26%) mortality. A 30-year-old, primigravida, at 33weeks 4 days of gestation presented to the emergency obstetrics department of Swaroop Rani Nehru Hospital, Prayagraj, Uttar Pradesh, India with a 2-day history of diffuse abdominal pain, distension and obstipation. The decision of emergency caesarean section was taken and a 2.5kg healthy female baby was delivered. Surgical opinion was sought intraoperatively. Segmental resection and anastomosis, adhesiolysis and appendicectomy was done. Patient discharged on 10 post-operative day along with her baby in satisfactory condition. Diagnosis of SBO can be difficult to make as symptoms are often attributed mistakenly to pregnancy and there can be a reluctance to request plain films owing to the risks of ionising radiation. Both of these factors can lead to a delay in diagnosis and initiating treatment. Clinical suspicion is vital and joint management between surgeons and obstetricians is crucial. In agreement with previous literature reviews regarding the need for prompt laparotomy in most cases of SBO, we recommend that patients with confirmed adhesional obstruction may be managed conservatively in the first instance but with a low threshold for progressing to laparotomy.
Análise quantitativa dos níveis de cortisol plasmático em alunos de ensino superior de Avaré-SP
Authors: Romão Franciele Gabriele , Ferraz Izabella , Bravim Giovana Cristina dos Reis , Vianna Juliana Nosse , Bannwart Castro Camila Ferreira 
Published: August 2021

O hormônio Cortisol é produzido nas glândulas adrenais e sua liberação ocorre através do ritmo circadiano. O aumento nos níveis de estresse, leva o sistema endócrino ativar-se, e mobilizar o eixo hipotálamo-pituitária-adrenal (HPA), resultando na maior liberação de hormônios glicocorticoides. O objetivo do trabalho foi realizar análises dos níveis de cortisol plasmático dos universitários, em dias normais e durante a semana de provas, para avaliar se a semana de provas influência nas alterações no nível desse hormônio. Um questionário sócio demográfico foi aplicado, para excluir fatores interferentes. Foram coletados 10 ml de sangue, de 10 estudantes do curso de Biomedicina. A análise do soro foi realizada pela técnica de Elisa sanduíche, e dados foram avaliados seguido pelo Wilcoxon, baseado no programa estatístico PRISM, (GraphPrism for Windows, version 6.01, GraphPad, EUA). Os voluntários foram divididos em grupos, conforme as características. Para comparar as duas coletas foi utilizado o valor da mediana, o resultado na primeira coleta foi de 21,13 ug/dL e na segunda 24, 45 ug/dL. Quando avaliados somente os resultados dos voluntários que não tinha nenhum fator interferente, a mediana foi de 10,9ug/dL, tendo um aumento de 0,4 ug/dL na semana de provas. A pesquisa apresentou alterações nos níveis de cortisol, porém não teve significância, apresentando o valor de 0,2754 (p<0,05). Concluiu-se que houve aumento das concentrações nos níveis de cortisol na semana de provas, mas não foi significativo, devido ao número de voluntários recrutados para o estudo, que foi um fator limitante na análise.
Os efeitos das intervenções farmacêuticas em pacientes ambulatoriais: Uma revisão sistemática
Authors: De Oliveira Vilaça Samara , Da Silva Sá Alves Elizama , Da Silva Santana Diego , Lo Prete Ana Cristina , Heitmann Mares Azevedo Ribeiro Carolina 
Published: August 2021

Os serviços clínicos liderados por profissionais farmacêuticos garantem segurança no uso de medicamentos em hospitais e na comunidade. Os farmacêuticos clínicos atuam resolvendo problemas relacionados aos medicamentos (PRMs) e contribuem na melhoria da qualidade de vida do paciente. Essa revisão tem como objetivo analisar a literatura para reafirmar a importância do farmacêutico na prática clinica do medicamento. Trata – se de um estudo de revisão sistemática, com o uso de termos Mesh (Medical Subject Headings) ou palavras de textos relacionadas a intervenções farmacêuticas, farmácia Clinica e atenção farmacêutica em bases de dados. Os critérios de exclusão foram estudos sem uma descrição clara nas intervenções e com intervenções multiprofissionais não lideradas pelo farmacêutico. Um total de 874 registros potencialmente relevantes foram identificados nos bancos de dados, dos quais 11 preencheram todos os critérios de elegibilidade e foram incluídos. Todos os estudos foram relatados no período de 2012 a 2019. O profissional farmacêutico possui um papel importante na identificação de PRMs e tomaram medidas para resolvê-los, incluindo o fornecimento de informações sobre medicamentos ou aconselhamento ao paciente (81,8%), ajustando medicamentos de apoio com base em protocolos previamente estabelecidos em colaboração com a equipe de saúde (18,2 %); Sugerindo mudanças na prescrição médica (18,21%). Concluímos que o farmacêutico clínico atua de maneira importante frente ao tratamento medicamentoso garantindo o uso racional e seguro do medicamento, porém são necessárias mais pesquisas para abordar as lacunas identificadas e explorar de maneira mais robusta o potencial de intervenções farmacêutica na prática clinica ambulatorial.
Assistência Júnior em Anestesiologia Veterinária: Relato de experiência
Authors: Pahim Alyssa Brum de Souza , Martins Felipe Pratalli , Orlandin Renata , Ribeiro Dimas Dal Magro , Valério Giovanna Bauer , De Oliveira Marília Teresa 
Published: August 2021

É imprescindível que a comunidade universitária, experiencie os pilares de ensino, pesquisa e extensão, que são bases do ensino superior. Desta forma, o presente trabalho objetivou relatar as experiências de atuação em um projeto de extensão que oferece um serviço inovador na fronteira oeste do Rio Grande do Sul, Brasil, o qual utiliza a metodologia ativa como estratégia de aprendizagem na área de Anestesiologia Veterinária. A metodologia utilizada é descritiva, e feita a partir da vivência dos estagiários protagonistas do projeto Assistência Júnior em Anestesiologia Veterinária (AJAV), desde a sua implantação até o final do primeiro semestre de atendimentos. A partir da participação de forma ativa nos primeiros meses de funcionamento do AJAV já foi identificado o potencial do projeto, o qual beneficiou os tutores dos pacientes com encaminhamento para procedimentos cirúrgicos, com consultas pré-anestésicas gratuitas, proporcionando contribuição social àqueles em condição de vulnerabilidade. E além do serviço oferecido para a comunidade, foi possível integralizar os saberes adquiridos nas disciplinas bases de medicina veterinária, promovendo uma vivência da prática de situações reais, que refletem a rotina de um médico veterinário anestesiologista, contribuindo para o amadurecimento intelectual e crítico dos discentes. Conclui-se que a inserção de uma atividade de extensão que possibilitou a prestação de serviço preparou os acadêmicos para o enfrentamento de problemas reais futuros na área médica e engrandeceu o setor da anestesiologia veterinária do Hospital Universitário Veterinário da Universidade Federal do Pampa.
IMPLEMENTATION OF TEN STEPS TOWARDS SUCCESSFUL BREASTFEEDING AT TANAH KALIKEDINDING HEALTH CENTER SURABAYA CITY, 2020
Authors: Date Wahyuni Mahmud , Anis Wahyul , Puspitasari Dwiyanti 
Published: August 2021

Abstract Background One of the government's efforts to increase the achievement of exclusive breastfeeding is the 10 LMKM program. Since 1991 in Indonesia, it has been introduced, but in its implementation it is not yet known by all health facilities even though several existing steps have been implemented, but the 10 LMKM policy has not been known by providers.Objectives Describe implementation and barriers to providers in program implementation, identify compliance and barriers to mothers as program recipients. Methods The research used descriptive qualitative research. The sampling technique used was purposive sampling to explore the implementation of 10 LMKM in Tanah Kalikedinding Health Center. Informants in accordance with the inclusion criteria 7 providers and 8 mothers as program recipients. Researchers interacted offline and online via video calls while adhering to health protocols. Results The implementation of 10 LMKM has been running with the internal policies of the Puskesmas referring to the Permenkes, carrying out tasks according to the SOP. Several providers have attended training and disseminated it to staff. Monitoring and evaluation is carried out through the credential team at the Puskesmas. Officers in implementing 10 LMKM to support the achievement of exclusive breastfeeding are committed to complying with the SOP. Provider barriers from external factors are the lack of health workers, especially midwives on duty, so that KIE regarding breastfeeding and others is not optimal. Mothers as program recipients when ANC is already in IEC, obediently follow the services provided and have not been fostered or referred to breastfeeding support groups. Barriers to exclusive breastfeeding in program implementation are influenced by external factors of working mothers. Conclusion The implementation of the 10 LMKM program at the Tanah Kalikedinding heath center has not been maximized.
URGENSI, PELUANG DAN KONSEP PEMBENTUKAN PENGADILAN KHUSUS LINGKUNGAN HIDUP DI INDONESIA
Authors: Yasir Muhammad 
Published: August 2021

Biarpun Indonesia telah lama memiliki UU Lingkungan Hidup, namun penegakan hukumnya masih belum sesuai harapan, tidak banyak pelaku pengrusakan lingkungan yang diadili di Pengadilan Negeri dan mendapat sanksi yang sesuai dengan kerusakan lingkungan. Tulisan ini bertujuan ingin mengetahui bagaimana urgensi, peluang dan konsep pembentukan pengadilan khusus lingkungan hidup di Indonesia.Hasil penelitian menunjukan bahwa: Pertama terdapat 4 urgensi pembentukan pengadilan lingkungan di Indonesia, yaitu 1) Ruang lingkup Lingkungan Hidup yang Luas, 2) Meningkatnya kejahatan Lingkungan Hidup, 3) Putusan pengadilan yang belum memberikan keadilan, dan 4) Lemahnya Kualitas Hakim. Kedua Terdapat peluang yuridis pembentukan pengadilan lingkungan hidup, yaitu: 1) Penjelasan Umum UU Nomor 32 Tahun 2009 tentang Perlindungan dan Pengelolaan Lingkungan Hidup, dan 2) Pasal 27 UU Nomor 48 Tahun 2009 tentang Kekuasaan Kehakiman. Ketiga Pengadilan lingkungan hidup yang dibentuk, 1) berada di lingkungan peradilan umum, 2) majelis hakim terdiri dari hakim karier dan adhoc, 3) berwenang memeriksa, mengadili dan memutus tindak pidana lingkungan hidup, dan 4) proses pemeriksaannya mengacu ke hukum acara pidana pada umumnya dan bersifat khusus.Kata Kunci : Lingkungan, Pengadilan Khusus
WATER LEVEL CONTROL SYSTEM IN ORNAMENTAL FISH PONDS USING SMS GATEWAY
Authors: Hakim Lukmanul , Hasan Basri Muhammad , Saravian Iskawanto Hilman 
Published: August 2021

Memelihara ikan hias adalah suatu hobi yang diminati masyarakat Indonesia, budidaya ikan bisa dibilang tidak sulit, hanya dibutuhkan ketelitian dan ketepatan dalam perawatan air agar terjaga baik, karena Indonesia memiliki curah hujan yang tinggi. Dari pemasalahan tersebut peneliti membuat alat yang dapat mengontrol air saat mencapai batas yang ditentukan saat turun hujan. Peneliti menggunakan menggunakan arduino sebagai kontroler, sim 800L sebagai pengirim peringatan, sensor ultrasonik sebagai pembaca permukaan air, servo sebagai pengontrol kran. Peneliti membuat program menggunakan aplikasi Arduino IDE untuk ditanamkan pada kontroler, untuk memastikan alat berfungsi dengan baik maka dilakukan pengujian perangkat keras dan menguji perangkat lunak sesuai desain yang diinginkan, setelah dirancang dan disatukan dilakukan pengujian total alat yaitu mengontrol ketinggian permukaan udara agar tetap pada posisi normal pada saat air hujan turun yaitu pada ketinggian 14 cm, jika permukaan air melebihi 14 cm maka kran akan terbuka dan mengirimkan peringatan berupa sms. Walaupun pemilik kolam tidak berada di sekitar kolam, tetapi masih mengtahui kondisi kolam saat turun hujan.
ANALYSIS OF HEAT ABSORBING PLATE ON DRYING RATE AND HEAT USEFUL FOR DRYING ANCHOVY
Authors: Mietra Anggara  , Pupung Pupung 
Published: August 2021

Pada tahun 2015 lalu kabupaten Sumbawa menghasilkan tangkapan ikan sebanyak 736.127 ton (Dinas kelautan dan Perikanan Kabupaten Sumbawa, 2019). Jumlah produksi ikan menurut Kecamatan di Kabupaten Sumbawa pada tahun 2015 yang terbanyak memproduksi ikan yaitu berada di kecamatan Plampang dengan jumlah 100.880 ton. Penelitian ini bertujuan untuk mengetahui pengaruh bentuk plat penyerap panas terhadap laju pengeringan dan panas yang berguna pada alat pengering ikan teri berbasis gas LPG. Variabel yang digunakan adalah bentuk plat gelombang, segitiga dan datar serta udara yang dihembuskan oleh kipas dari luar dengan kecepatan 0,5 m/s, 1 m/s dan 1,5 m/s. Hasil yang didapatkan pada penelitian ini yaitu panas berguna tertinggi didapatkan 21,25 Watt pada kecepatan 0,5 m/s. Sedangkan panas berguna terendah terdapat plat penyerap panas berbentuk datar yaitu sebesar 2,83 watt. laju pengeringan terbaik terdapat pada plat bergelombang yaitu sebesar 1,84 g/menit dan terendah terdapat pada bentuk plat datar yaitu sebesar 1,08 g/menit. kadar air ikan teri kering sebesar 17,1 % dan terbanyak pada plat datar yaitu 80,05 %.
Pengaruh Kepemilikan Institusional, Konsentrasi Kepemilikan Dan Dividen Terhadap Kinerja Perusahaan
Authors: Wikartika Ira , Syaiful Akbar Fajar 
Published: August 2021

Improving company performance is crucial for the company's future life continuity. The company has a primary objective that increases the prosperity of shareholders. Basically, investors expect returns in the form of dividends. The structure of ownership and dividends is one way to improve the company's performance. This research aims to determine the influence of institutional ownership, ownership concentration, and dividends on the company's performance. The research methods used are quantitative methods using multiple linear regression analysis techniques. The research population uses companies listed on LQ45 in the Indonesia Stock Exchange. Sample research of 45 companies during the year 2018. The results showed that institutional ownership and ownership concentration did not affect the company's performance while dividends were influential in the company's performance.
Pengaruh Citra Merek, Kepercayaan Merek dan Sikap Merek terhadap Minat Menjadi Nasabah Tabungan dan Giro Bank Panin (Studi pada Bank Panin KCP Tambak Langon Surabaya)
Authors: Al Azis Mochamad Syaifudin , Harsono Soni 
Published: August 2021

Pada era Globalisasi persaingan bisnis antar Bank semakin ketat. Bank yang ingin terus berkembang dan meningkat harus mampu memberikan produk yang berkualitas. Namun, untuk menjadi Bank yang unggul dalam persaingan bukanlah sebuah hal yang mudah, diperlukan pengelolaan manajemen yang bagus dan berkualitas. Selain itu dibutuhkan pula strategi yang maksimal.
Menurut UU RI No.10 1998, Bank merupakan badan usaha yang menghimpun dana dari masyarakat dalam bentuk simpanan dan menyalurkannya kepada masyarakat dalam bentuk kredit dan atau bentuk-bentuk lainnya dalam rangka meningkatkan taraf hidup masyarakat banyak. OJK mencatat hingga akhir Desember 2018, ada sebanyak 115 Bank di Indonesia dengan komposisi ada 5 Bank BUKU IV dan menguasai 51,03% asset perbankan. Bank BUKU III ada 28 Bank dengan pengusaan asset 35,23%. Bank BUKU II sebanyak 59 Bank dengan pangsa asset 12,65% dan Bank BUKU I sebanyak 22 Bank dan penguasaan asset hanya 1,08%. Di antara Bank tersebut, terdapat Bank Panin yang didirikan pada tahun 1971 yang merupakan hasil dari merger dari 3 Bank, yaitu Bank Kemakmuran, Bank Industri Jaya dan Bank Industri Dagang Indonesia. Berdasarkan data keuangan per September 2018, Bank nasional dengan asset tertinggi masih disematkan pada Bank BRI, peringkat ke dua terdapat Bank Mandiri, diikuti secara berututan Bank BCA, Bank BNI, Bank BTN, Bank CIMB Niaga, Bank Panin, Bank OCBC NISP,
The Impact of Gridded Weather Database on Soil Water Availability in Rice Crop Modeling
Authors: Menezes Caio Teodoro , Casaroli Derblai , Heinemann Alexandre Bryan , Moschetti Vinicius Cintra , Battisti Rafael 
Published: August 2021

Abstract
In recent years, there has been an increase in studies suggesting that gridded weather database (GWD) is a suitable source for simulating crop yield. Brazil has low geospatial coverage by measured weather database (MWD). Based on that, this study aimed to compare two different GWD sources, Daily Gridded (DG) and NASA/POWER (NP), on the simulated yield of upland rice (UR) against the MWD input. The GWD and MWD were obtained for seven locations across UR Brazilian region, considering a period ranging from 1984 to 2016. GWD and MWD were used to estimate rice potential (Yp) and attainable yield (Ya), in clay soil and sandy soil, using ORYZA (v3) model. DG had the best performance for all variables. GWD-based yields had a reasonable performance. However, DG had a slightly better performance than NP in all conditions, DG-based yields showed RMSE values of 0.57, 0.71 and 0.52 for Yp and Ya in clay and sandy soil, whereas NP showed RMSE values of 0.86, 0.91 and 0.64. DG also showed higher R² and d values for yields assessed. Both GWD overestimated Ya, these overestimations in DG-based yield were 3.54, 9.61, and 21.35% for Yp and Ya in clay and sandy soil respectively, in NP-based yield were 13.67, 18.45, 29.11%, showing that for both GWD-based yield increased as the soil type texture as well as water storage decreased. As a consequence, we do not recommend the use of precipitation data in daily time-step crop modeling.
The Study of Distance Changes Between Lumbar Bi-Cortical Pedicle Screws and Anterior Large Vessels in Patients with Lumbar Spondylolisthesis
Authors: Zhao Li , Wan Chenguang , Han Shuhong , Zheng Shaoyi , Li Baofeng 
Published: August 2021

Abstract
Objective: This paper was a anatomical radiographic study of distance between lumbar bi-cortical pedicle screws (BPSs) and anterior large vessels (ALVs) in patients with lumbar spondylolisthesis, and to provide clinical basis for evaluating the safety of bi-cortical pedicle screw implantation during lumbar spondylolisthesis.Methods: Complete Computed tomography (CT) data of 104 patients with grade I lumbar spondylolisthesis (L4 52 and L5 52) and 107 non-spondylolisthesis patients (control group) were collected in this study. The distances between lumbar 4,5(L4,5) and sacrum 1(S1) BPSs and ALVs (abdominal aorta, inferior vena cava, left and right common iliac artery, internal and external iliac artery) were respectively measured at different transverse screw angles (TSAs) (L4:5°,10°; L5:10°,15°; S1:0°,5°,10°) and analyzed by SPSS (v25.0). There were three types of distances from the anterior vertebral cortex (AVC) to the ALVs (DAVC-ALV): DAVC-ALV N, DAVC-ALV ≥ 0.50 cm, and DAVC-ALV < 0.50 cm; these different distances represented non-contact, distant and close ALV respectively.Results: We calculated the incidences of large vessels damage at different TSAs and provided the appropriate angle of screw implantation. In non-spondylolisthesis group, in L4, the appropriate left TSA was 5°, and the incidence of the close ALV was 4.62%. In S1, the appropriate left TSA was 0° and the incidence of the close ALV was 22.4%, while the appropriate right TSA was 10° and the incidence of the close ALV was 17.8%. In L4 spondylolisthesis group, in L4, the appropriate left TSA was 5°, and the incidence of the close ALV was 3.8%. In L5 spondylolisthesis group, in S1, the appropriate left TSA was 0° and the incidence of the close ALV was 19.2%, while the appropriate right TSA was 10° and the incidence of the close ALV was 21.2%. The use of BPS was not appropriate on the right side of either L4 or on the either side of L5 both in spondylolisthesis and control group. In patients with lumbar 4 spondylolisthesis, the incidences of large vessels damage were less than the control group in both L4 and 5. In patients with lumbar 5 spondylolisthesis, the incidences of large vessels damage were less than the control group in L5, while there were no significant difference in S1.Conclusion: It is very important that considering the anatomical relationship between the AVC and the ALVs while planning BPSs. The use of BPS do not apply to every lumbar vertebra. In patients with lumbar spondylolisthesis and non-spondylolisthesis patients, the incidences of large vessels damage are different.
Randomized Double-Blind Clinical Trial Comparing Safety and Efficacy of the Biosimilar BCD-021 with Reference Bevacizumab
Authors: Stroyakovskiy Daniil , Fadeeva Natalya , Matrosova Marina , Shelepen Konstantin , Adamchuk Grigoriy , Roy Bodhisatta , Nagarkar Rajnish , Kalloli Mahesh , Zhuravleva Daria , Voevodin Georgiy , Shustova Mariya , Kryukov Fedor 
Published: August 2021

Abstract
Background
BCD-021 is a bevacizumab biosimilar which was shown to be equivalent to reference bevacizumab in a wide panel of physicochemical studies as well as preclinical studies in vitro and in vivo. International multicenter phase III clinical trial was conducted to compare efficacy and safety of BCD-021 and reference bevacizumab in combination with paclitaxel and carboplatin in a first-line treatment of inoperable or advanced non-squamous non-small-cell lung cancer (NSCLC).
Methods
Patients with no previous treatment for advanced non-squamous NSCLC were randomly assigned 3:2 to BCD-021 or reference bevacizumab and were treated with bevacizumab + paclitaxel + carboplatin. Therapy continued for 6 cycles (every 3 weeks), until progression of the disease or unbearable toxicity. The primary study endpoint was the overall response rate. The study goal was to prove the equivalent efficacy of BCD-021 and reference bevacizumab. Equivalence margins for 95% CI for the difference in the overall response rates were set at [-18%; 18%], for 90% CI for the ratio of overall response rate were set at [67%; 150%].
Results
In total 357 patients were enrolled in the study, 212 in the BCD-021 group and 145 in the reference bevacizumab group. The ORR was 34.63% in the BCD-022 group and 33.82% in the reference bevacizumab group. Limits of 95% CI for the difference in overall response rates between the groups were [-9.47%; 11.09%]. Limits of 90% CI for the ratio of overall response rate between the groups were [79.6%; 131.73%]. For both approaches CI lied within predetermined equivalence margins. Profile of adverse events (AEs) was similar between the groups (any AEs were reported in 86.89% of patients in BCD-021 group and 89.05% of patients in reference group). No unexpected adverse reactions were reported throughout the study. No statistically significant differences regarding anti-drug antibody occurrence rate was found between BCD-022 (n = 4; 1.96%) and comparator (n = 5; 3.65%). Both drug products showed low occurrence rate and short life of anti-bevacizumab antibodies. Pharmacokinetics assessment after 1st and 6th study drug injection also demonstrated equivalent PK parameters by all outcome measures.
Conclusions
Thus, the results of this study demonstrated therapeutic equivalence of bevacizumab biosimilar BCD-021 and referent bevacizumab drug.
Trial registration:
The trial was registered with ClinicalTrials.gov (Study Number NCT01763645, date of registration 09/01/2013).