bluuebunny/crossref_metadata_2025_split huggingface dataset:
Changing trends in coagulation profile of 30 patients undergoing CRS with HIPEC in the peri-operative period
Authors: Pathak Soumi 
Published: February 2021

Background: With advent of surgical advancements like HIPEC several unstudied pathophysiological aspects need to be evaluated. We studied the trends in coagulation profile in patients undergoing CRS with HIPEC in the peri-operative period, utilizing Thromboelastography (TEG) in comparison with standard coagulation tests. The utility of TEG as a guide for transfusion of blood products was also evaluated.
Materials and Methods: It was a Prospective observational Cohort study which included 30 consecutive patients undergoing CRS with HIPEC at RGCI in 2015.
Methodology: Preoperatively standard coagulation tests were done as a baseline. Intra-operative arterial blood samples were collected for ABG, PT, APTT, and TEG at following time points: before starting of HIPEC, after completion of HIPEC and on 1 and 2 postoperative days. Statistical analysis was done using Chi-square test and unpaired t-test for categorical and continuous variables. Pearson’s correlation coefficient was calculated for analysing the correlation between the variables. P < 0.05 was considered statistically significant.
Results: A strong correlation was observed between PT & R values of TEG. Similar correlation was also observed between the α angle, MA of TEG and platelet count throughout the peri-operative period. Immediately post HIPEC, we observe value of APPT decreases while the other parameters of coagulation profile showed a rising trend. R value showed rising trend after CRS, a dip after HIPEC followed by a rising trend on first post operative day which normalizes only after second post operative day. It gives a mixed picture of both hypo and hyper coagulable state. α angle, MA rise immediately after HIPEC and continue to rise till the second postoperative day. There was no requirement of transfusion of blood and blood products as guided by the TEG findings and no clinical evidence of any bleeding or thromboembolic episode occurred.
Conclusion: To conclude, our study demonstrated TEG to be a useful and comprehensive tool to assess coagulopathy and accordingly guide blood product transfusion in patients undergoing CRS with HIPEC.
Unusual clinical presentation of chriocarcinoma in young patients – Neulological meatastasis
Authors: Yadav Sushma 
Published: February 2021

Introduction: Choriocarcinoma is a malignant trophoblastic tumor, usually of placenta and characterized by ‘early hematogenous spread’ to lungs. Choriocarcinoma of placenta is preceded by – H. Mole (50%), spontaneous abortion (20%), ectopic pregnancy (2%) and normal term pregnancy (20%-30%). It is chemosensitive tumor and even in metastatic lesion cure rate is 90%-95%. Most common site of metastasis is lung and vagina, vulva, kidney, liver, ovaries, brain and intestine. If tumor is not diagnosed and managed timely, because of its vascularity, it bleeds profusely leading to death.
Cases: We encountered 2 rare cases, with age of 25 and 27 years respectively with choriocarcinoma with unusual clinical presentation. Both patients presented with neurological symptoms of brain metastasis and succumbed to death within a short span of time. In both cases histopathological report failed to detect chorio-carcinoma but b-HCG and radiological findings were suggestive of choriocarcinoma.
Conclusion: If b–HCG level are unusually high with radiological findings, the patients should be considered for chemotherapy even if HPE is inconclusive. Without chemotherapy chorio-carcinoma has a rapid progression and mortality which can be prevented by early suspicion and timely management.
R-VEIL in carcinoma vulva
Authors: Jain Vandana , Sekhon Rupinder , Giri Shveta , Rawal Sudhir 
Published: February 2021

Background: Vulvar cancer accounts for about 3-5% of gynaecologic malignancies. Prognosis is strongly dependent on presence of inguinofemoral lymph node metastases. Effective management of regional lymph nodes is the most important factor in the curative management of early vulvar cancer. Despite careful dissection and maintaining vascularity of skin, surgical morbidity is seen in 50% cases. Video – endoscopic inguinofemoral lymphadenectomy was developed by Bishoff in 2003 by dissecting two cadaveric models and in one patient with stage T3N1M0 penile carcinoma. VEIL is an alternative to reduce the morbidity without compromising the oncologic outcomes. VEIL has continued to evolve into single site and robotic variants. R-VEIL is a minimally invasive procedure duplicating the standard open procedure with less morbidity.
Aims and Objectives: A video presentation to describe the technique of R-VEIL in vulvar cancer and discuss the advantages and outcome.
Conclusions: R – VEIL is an attractive minimally invasive technique to do inguinal block dissection in a single sitting in patients with vulvar carcinoma as the surgeon does not get tired as happens in VEIL technique. R-VEIL allows the removal of inguinal lymph nodes within the same limits as in open procedure and potentially reduces surgical morbidity. It is better accepted cosmetically and reduces hospital stay. Long term oncological results are not available. Randomized multi-institutional studies are required to prove its efficacy over open counterpart.
Aggressive Therapy for Acute Pulmonary Embolism: Systemic Thrombolysis and Catheter-Directed Approaches
Authors: Todoran Thomas M. , Petkovich Bradley 
Published: February 2021

AbstractVenous thromboembolism (VTE) is the third most common cause of cardiovascular disease after myocardial infarction and stroke. Population-based studies estimate that up to 94,000 new cases of pulmonary embolism (PE) occur in the United States annually with an increasing incidence with age. Mortality from PE is the greatest in the first 24 hours, with a decreased survival extending out 3 months. Thus, acute PE is a potentially fatal illness if not recognized and treated in a timely manner. Contemporary management includes systemic anticoagulation, thrombolysis, catheter-based procedures, and surgical embolectomy. This article reviews current clinical evidence and societal guidelines for the use of systemic and catheter-directed thrombolysis for treatment of acute PE.
Anticoagulation Prescription and Outcomes in Relation to Renal Function in Patients with Atrial Fibrillation: Results from GLORIA-AF
Authors: van der Wall Sake J. , Teutsch Christine , Dubner Sergio J. , Diener Hans-Christoph , Halperin Jonathan L. , Ma Chang Sheng , Rothman Kenneth J. , Paquette Miney , Zint Kristina , França Lionel Riou , Lu Shihai , Lip Gregory Y. H. , Huisman Menno V. ,   on behalf of the GLORIA-AF Investigators
Published: February 2021

Abstract
Objective Anticoagulation management in patients with atrial fibrillation (AF) and impaired renal function is challenging. This study aimed to evaluate anticoagulation prescription patterns in relation to renal function and to describe 2-year clinical outcomes among dabigatran users.
Methods Global Registry on Long-Term Oral Antithrombotic Treatment in Patients with Atrial Fibrillation (GLORIA-AF) is an international, prospective, and observational study program involving patients with newly diagnosed AF at risk for stroke. Prescription patterns were assessed by creatinine clearance (CrCl) at enrollment. Dabigatran users were followed for 2 years. Clinical outcomes were standardized for stroke and bleeding risk, based on CHA2DS2-VASc and HAS-BLED scores, with missing values imputed.
Results Baseline CrCl values were available for 12,056 of 15,308 eligible patients (79%). With declining renal function, prescriptions increased for vitamin K antagonists (VKAs) and decreased for dabigatran (30–47% and 34–12%, respectively). The prescription of other non-vitamin K antagonists remained similar across CrCl groups (14–19%). In 4,873 dabigatran users, standardized stroke rates were low across all CrCl groups; 0.58/100 patient-years (95% confidence interval [CI]: 0.30–0.90) in CrCl ≥80 mL/min, 0.85 (95% CI: 0.48–1.21) in CrCl 50 to 79 mL/min, and 0.33 (95% CI: 0.06–1.11) in CrCl 30 to 49 mL/min. Similarly, major bleeding rates were low and numerically increased with declining renal function (0.68/100 patient-years, 95% CI: 0.39–1.03; 0.92, 95% CI: 0.58–1.32; and 1.26, 95% CI: 0.66–1.97, respectively).
Conclusion In patients with AF, VKA prescriptions increased and dabigatran prescriptions decreased with declining renal function. Rates of stroke and major bleeding in dabigatran patients remained low across the categories of renal impairment.
Do Millennials share similar perceptions of brand experience? A clusterization based on brand experience and other brand-related constructs: the case of Netflix
Authors: Amoroso Sara , Pattuglia Simonetta , Khan Imran 
Published: February 2021

AbstractThis study aims to explore, in the case of the Over-The-Top (OTT) sector, Millennials’ perceptions of brand experience in relation to the well-established brand Netflix. In particular, the work addresses a clusterization of Millennials on the basis of their experience with the brand. The study first explores the theoretical background, highlighting current perspectives on Over-The-Top industry and on brand experience as a strategic process for creating holistic customer value, achieving differentiation and sustainable competitive advantage. Second, it offers a quantitative study (using a survey) and highlights the principal results related to the brand. Moreover, this work will attempt to use cluster analysis methodology exploiting brand experience validated scale and other related brand and behavioural constructs to cluster consumers. Both academics and marketing managers should focus on approaches able to deliver strong and memorable brand experiences. A positive and durable brand experience is related to other important consequences for consumer action and behaviour, such as the willingness to place brand trust, consumer loyalty towards the brand, an enduring consumer-brand relationship, repurchase intentions, and lastly, the long-term life of the brand
The impact of artificial intelligence along the insurance value chain and on the insurability of risks
Authors: Eling Martin , Nuessle Davide , Staubli Julian 
Published: February 2021

AbstractBased on a data set of 91 papers and 22 industry studies, we analyse the impact of artificial intelligence on the insurance sector using Porter’s (1985) value chain and Berliner’s (1982) insurability criteria. Additionally, we present future research directions, from both the academic and practitioner points of view. The results illustrate that both cost efficiencies and new revenue streams can be realised, as the insurance business model will shift from loss compensation to loss prediction and prevention. Moreover, we identify two possible developments with respect to the insurability of risks. The first is that the application of artificial intelligence by insurance companies might allow for a more accurate prediction of loss probabilities, thus reducing one of the industry’s most inherent problems, namely asymmetric information. The second development is that artificial intelligence might change the risk landscape significantly by transforming some risks from low-severity/high-frequency to high-severity/low-frequency. This requires insurance companies to rethink traditional insurance coverage and design adequate insurance products.
The electron–phonon coupling coefficient for high-temperature superconductors
Authors: Chauhan Radhika , Indu B. D. 
Published: February 2021

The expression for the electron–phonon coupling coefficient (gk) is obtained by solving a six order polynomial equation obtained via the quantum dynamical many-body theory of the electron and phonon Green’s function for high-temperature superconductors (HTSs). The developed equation depends on the temperature; electron, phonon, and pairon frequencies; and distribution functions. The YBa2Cu3O7−δ cuprate superconductor has been used for the purpose of analysis and is found to be in agreement with the fact that gk decreases with the increase in temperature above 0 K. The distinct behavior obtained via dispersion for gk in different directions, [100] and [010], marked the anisotropy of electron–phonon coupling in HTSs. The derived expression for gk is further used for the evaluation of the superconducting gap via the Bardeen–Cooper–Schrieffer and the McMillan gap equation and both superconducting gap equations approach the Tc value for YBa2Cu3O7−δ, and the obtained reduced gap ratio [2Δ(0)/kBTc] is found to be in the limit of the reduced gap ratio of HTSs.
Beaconless PAT and adaptive beam control using variable focus lens for free-space optical communication systems
Authors: Mai Vuong V. , Kim Hoon 
Published: February 2021

Free-space optical communications (FSOCs) have recently emerged as a promising solution for various communication scenarios. However, the pointing, acquisition, and tracking (PAT) is a technically challenging issue, especially in airborne FSOC systems. In this paper, we present an adaptive beam control technique combined with beaconless PAT using a variable focus lens. By using the lens whose focal length can be tuned electrically, we facilitate the coarse PAT by enlarging the beam size and also mitigate the adverse effects of pointing errors by adjusting the beam divergence angle adaptively to the link conditions. The major benefit of the proposed scheme is that the beam control can be implemented in a simple and compact manner, without relying on mechanical movements. We carry out a proof-of-concept experimental demonstration of the proposed scheme for a 10-Gb/s free-space optical link over 104 m. The demonstration shows that the probability of PAT success can be improved considerably by using the proposed scheme. It also shows that the proposed scheme could result in a system loss reduction of 6.4 dB and improve the tolerance to pointing errors up to 500 μrad for a target bit-error ratio of 10−3. The response time of the lens is measured to be &lt;211 ms. We confirm experimentally that the receiver size and the amount of pointing error determine the optimum beam size at the receiver.
A critical role of the soybean evening complex in the control of photoperiod sensitivity and adaptation
Authors: Bu Tiantian , Lu Sijia , Wang Kai , Dong Lidong , Li Shilin , Xie Qiguang , Xu Xiaodong , Cheng Qun , Chen Liyu , Fang Chao , Li Haiyang , Liu Baohui , Weller James L. , Kong Fanjiang 
Published: February 2021

Significance
In many plant species, the timing of flowering is sensitive to photoperiod. In many crop species, genetic variation in this sensitivity is critical for adaptation to specific regions and management practices. This study identifies a component of the genetic pathway controlling flowering time in soybean, a legume crop of major global importance. Notably, plants lacking this component flower extremely late. Photoperiod sensitivity in plants, including soybean, was first systematically described in a seminal paper 100 y ago, and the results presented here establish an important new molecular step underlying this response. This step is a critical control point that could be genetically adjusted to engineer photoperiod sensitivity for yield improvement across a broad range of locations and agricultural contexts.
Changing personality traits with the help of a digital personality change intervention
Authors: Stieger Mirjam , Flückiger Christoph , Rüegger Dominik , Kowatsch Tobias , Roberts Brent W. , Allemand Mathias 
Published: February 2021

SignificancePersonality traits have consequences and are malleable throughout the lifespan. However, it is unclear if and how personality traits can be changed in desired directions. A 3-mo digital personality change intervention was deployed, and a large-scale randomized controlled trial (n= 1,523) was conducted to examine the effects of intended personality change in a nonclinical sample. The intervention group showed greater changes than the control group, and changes aligned with intended goals for change. Observers also perceived personality changes, but reported changes were less pronounced. Moreover, self- and observer-reported changes persisted until 3 mo after the end of the intervention. These findings provide the strongest evidence to date that normal personality traits can be changed through intervention in nonclinical samples.
Gender assignment strategies and L1 effects in the elicited production of mixed Spanish-Basque DPs
Authors: Munarriz-Ibarrola Amaia , Ezeizabarrena Maria-José , Arrazola Varun DC , Parafita Couto M. Carmen 
Published: February 2021

Abstract
This paper investigates the strategies involved in gender assignment in Spanish-Basque mixed Determiner Phrases
(DPs) with a gendered Spanish determiner (el
M /la
F) and a Basque ungendered noun. Previous studies on Spanish-Basque mixed DPs
have revealed conflicting results regarding the determining factor affecting gender assignment, namely, phonological ending vs.
analogical gender. We designed a forced-switch elicitation task in order to elicit mixed DPs with a Spanish determiner and a
Basque noun (controlled for both phonological vs. analogical cues). Thirty highly proficient Spanish-Basque bilinguals with
different profiles and socio­linguistic backgrounds participated in the study. Three cues were significant in the selection of the
Spanish M/F determiner: the analogical gender and two phonological cues, the word ending and the root ending of the Basque noun.
Further statistical analyses revealed participants’ L1 as a strong factor in the variability attested: bilinguals with Spanish as
(one of) their L1(s) rely predominantly on the analogical criterion, whereas speakers with only Basque as L1 follow mainly the
phonological criterion. Overall, this study provides an explanation for the previous conflicting results and highlights the fact
that bilinguals may use different strategies depending on their bilingual profile and the morpho-phonological properties of the
languages in contact.
Making sound visible—a simple schlieren imaging setup for schools
Authors: Veith Sonja Isabel , Friege Gunnar 
Published: February 2021

Abstract
Sound is an interesting topic for physics lessons at all ages. However, it is difficult to illustrate this ubiquitous phenomenon and many models do not adequately represent the properties of sound and thus promote unwanted conceptions. The experiment presented here avoids this by visualising sound itself with the help of the schlieren technique. For this purpose, an easily reproducible variant of a schlieren setup is presented. The simple setup is described in detail.
The discrepancies in different facets of MgB2 bulk superconductors prepared under various sintering durations by spark plasma sintering
Authors: Zhang J Y , Zhang Y F , Lou Z W , Zhang P H , Li C Y , Yuan J W , Peng L , Ma Y X , Noudem J G , Izumi M 
Published: February 2021

Abstract
Seven MgB2 bulk superconductors with good superconductivity and crystallinity were prepared under the pressure of 50 MPa at 950 °C and different sintering durations (15 ∼ 240 min) by spark plasma sintering (SPS), with the onset critical temperature (T
c,onset) around 37.5 K. The superconducting properties and microstructure measured from the facets perpendicular (PeF) and parallel (PaF) to the compression direction of the SPSed MgB2 bulk samples were also analyzed to investigate the effect of the sintering duration on the MgB2 bulks and the discrepancy between the PeF and the PaF. The optimum performance was obtained from the sample prepared for 45 min for both facets, and the critical current density (J
c) measured from the PeF and the PaF are 364 kA cm−2 and 344 kA cm−2 in self field at 20 K, respectively. The PeF exhibits better Jc
performance than the PaF at low fields and the PaF exhibits better J
c performance than the PeF at high fields. It can be concluded that the sintering duration affects the properties of the PeF mainly by changing their crystallite size. While for the PaF, the sintering duration mainly affects the microstructural defects, such as cracks, pores and secondary phase particles, thus further affecting their J
c performances. In terms of the flux pinning mechanism of the SPSed MgB2 bulk samples, the PaF is less susceptible to sintering duration than the PeF, and the better J
c performance of the PaF at high fields is due to the stronger grain boundary pinning. It can be also found that the point pinning being stronger at higher temperature is the result of the decreasing anisotropy of MgB2 bulk samples with the temperature.
Improving reliability of power supply of mineral-raw-material complex
Authors: Minakova T E 
Published: February 2021

Abstract
The problem of ensuring the reliability of the main equipment of enterprises of the mineral and raw materials complex is considered. The significant influence of automatic control means on the automatic power supply system (object of study) on the efficiency of mining enterprises is shown. Achieving the goal of improving uninterrupted power supply for the operation of electrical installations of the mining complex is ensured by solving the problem of reducing the time of disconnection of damaged areas and transient processes. For this, an algorithm has been developed that uses a set of signs of emergency situations: values of voltages, currents, states of relay protection actuators and automation. In addition, the integration of automatic power supply control and relay protection based on the concept of smart power supply networks of a mining enterprise has been proposed. A sign of identification of the type of emergency mode was by the level of voltage reduction on the buses of the switchgear, control of the actuation of relay protection devices that disconnect equipment in emergency mode, autoreclosing, underfrequency load shedding, automatic reserve entry. MATLAB/Simulink simulated the operation of electrical equipment of the power supply system in accordance with the known method of relay protection and automation, as well as using the proposed algorithm for identifying emergency modes and restoring voltage after disconnection of the damaged area.
Digital technologies in modeling and design of mining excavators
Authors: Shibanov D A , Ivanov S L , Shishkin P V 
Published: February 2021

Abstract
Development and application of digital technologies at the stage of new model design is highly relevant. Manufacture of a testbed vehicle and its full-scale pilot testing is impossible for Russian manufacturers of mining excavators due to a high cost of a prototype and a lack of special testing grounds. In order to reduce the risks of machine builders as vehicle manufacturer and those of MPPs as users of the prototype excavator, it is necessary to introduce and develop the digital twin technology at the stage of designing new models. A general reference point in development of the digital twin of a mining excavator is minimizing human input. Due to integration of works by stages of creation of the digital twin in a form of an information diagnostic system, there is a possibility to manage the life cycle of the product and optimize MRO with accounts of actual conditions and operating modes.