bluuebunny/crossref_metadata_2025_split huggingface dataset:
Asymmetric Determinants of CO2 Emissions in China: Do Government Size and Country Size Matter?
Authors: Lan Hai , Cheng Chengping , Sohail Muhammad Tayyab 
Published: November 2021

Abstract
CO2 emission reduction is a long-term strategy for China to promote its government and country size. However, this study examines the asymmetric impact of government size and country size on CO2 emissions in China. The study embraces the nonlinear ARDL framework of time series data analysis as proposed by Shin et al. (2014), which disentangles the positive and negative shocks to government size and country size. We find that the response of CO2 emissions to government size and country size positive shocks differs from the negative shocks. Empirical outcomes revealed that a positive shock of government size exerts an insignificant positive on CO2 emissions, while a negative shock of government size reduces CO2 emissions. More specifically, a positive shock of country size mitigates the CO2 emissions of China in long run. Policymakers should redesign the energy and environment policies in the framework of government size and country size.
Clinical Features of Congenital Pseudarthrosis of the Tibia in Children：a Study Focusing on 514 Cases in China
Authors: Zhou Yijun , Tan Qian , Liu Kun , Liu Yaoxi , Zhu Guanghui , Mei Haibo , Yang Ge 
Published: November 2021

Abstract
Background: Congenital pseudarthrosis of the tibia (CPT) is a refractory and rare disease. Because of its extremely low incidence, little is known about its clinical features. In this retrospective study, the aim of this study was to analyze the clinical characteristics of patients with CPT. Methods: This is a retrospective study of children with CPT identified by radiological review. Investigations of CPT included general condition, the characteristics of CPT, treatment methods and surgical complications. Results: We have collected 514 CPTs from 1999 to March 2020 in our hospital, 317 (61.67%) boys, 197 (38.33%) girls; 330 (62.86%) in Crawford IV; 510 (97.14%) in mid and distal 1/3 tibia; 481 (93.58%) in less than 3 years of first appearance of symptom; 297 (57.78%) in less than 3 years of the first visit of outpatient. The most common postoperative complication was ankle valgus (101, 39.60%), followed by limb length discrepancy（91, 35.69%), refracture (38, 14.90%), osteomyelitis (15, 5.88%) and removal of internal fixation (10,3.93%) . Conclusions: CPT with higher incidence of Crawford IV frequently occurs in boys and middle or distal part of the tibia; most patients have the first appearance of symptom and the first visit of outpatient before 3 years; the major surgical complications were ankle valgus and limb length discrepancy.
Effect of A Positive Cumulative Fluid Balance On The Prognosis of Patients With Sepsis In The Xining Area
Authors: Ma Si-Qing , Wang Yun , Sun Bin , Wang Hao , Xu Xue-Xia , Yin Zhi-ying , Luo Junming 
Published: November 2021

Abstract
Background: The aim of this work is to analyze the effect of a positive cumulative fluid balance and relative clinical indicators on the prognosis of patients with sepsis in the Xining area, China.Methods: The clinical data of 480 sepsis patients (313 males and 167 females, aged 52–77 (65) years) admitted between January 2017 and December 2019 were retrospectively analyzed. The APACHE II score, SOFA score, SIRS score and clinical laboratory test indicators of the patients were collected. Receiver operating characteristic (ROC) curves were used to analyze the sensitivity and specificity of each indicator in predicting the poor prognosis of patients with sepsis, and the maximum Youden index was used to determine threshold values. Cox regression analysis was performed to assess patient prognosis using data from patients with different fluid balances. Results: The following clinical indicators were significantly different between the 2 groups (P<0.05): APACHE II score, SOFA score, SIRS score, PCT, IL-6, BNP, CRP, PLT, BUN, CREA, Lac and total fluid balance from days 1 to 5. The area under the ROC curve (AUC) for total fluid balance from days 1 to 5 was 0.558, the cut-off value was 2120.5 mL, the sensitivity was 54.0%, and the specificity was 58.1%. The survival rates were different between the 2 groups (60.9% vs 48.9%, P<0.05). Total fluid balance was significantly higher in patients with septic shock and with Lac>2.0 mmol/L (P<0.05). Cox regression analysis indicated that APACHE II score, SOFA score, PLT score, Lac, and total fluid balance from days 1 to 5 were independent risk factors for poor prognosis.Conclusion: A positive fluid balance from days 1 to 5 after ICU admission was associated with poor patient outcomes and was an independent risk factor for poor patient prognosis.
Carriage of mutations R462Q (rs 486907) and D541E (rs 627928) of the RNASEL gene and risk factors in patients with prostate cancer in Burkina Faso.
Authors: Kadanga Essonan , ZOURE Abdou Azaque , Zohoncon Théodora M. , Traoré Lassina , Ky Bienvenu Désiré , Yonli Albert Théophane , Bazié Bapio , Sombié Hermann Karim , Sorgho Pegdwendé Abel , Frida Tovo , Ouédraogo Clarisse , Djigma Florencia W. , Simpore Jacques , Traoré Aida , Traoré Kalifou 
Published: November 2021

Abstract
Background

Prostate cancer (Pca) is a public health problem that affects men, usually of middle age or older. It is the second most common cancer diagnosed in men and the fifth leading cause of death. The RNASEL gene located in 1q25 and identified as a susceptibility gene to hereditary prostate cancer, has never been studied in relation to prostate cancer in Burkina Faso. The aim of this study was to analyze the carriage of RNASEL R462Q and D541E mutations and risks factors in patients with prostate cancer in the Burkina Faso.
Methods

This case-control study included of 38 histologically diagnosed prostate cancer cases and 53 controls (cases without prostate abnormalities). Real-time PCR genotyping of R462Q and D541E variants using the TaqMan® allelic discrimination technique was used. Correlations between different genotypes and combined genotypes were investigated.
Results

The R462Q variant was present in 5.3% of cases and 7.5% of controls. The D541E variant was present in 50.0% of cases and 35% of controls. There is no association between R462Q variants (OR= 0.60; 95%IC, 0.10 - 3.51; p= 0.686) and D541E variants (OR=2.46; 95%IC, 0.78 - 7.80; p= 0.121) and genotypes combined with prostate cancer. However, there is a statistically significant difference in the distribution of cases according to the PSA rate at diagnosis (p ˂ 0.001). For the Gleason score distribution, only 13.2% of cases have a Gleason score greater than 7. There is a statistically significant difference in the Gleason score distribution of cases (p ˂ 0.001)
Conclusions

These variants, considered in isolation or in combination, are not associated with the risk of prostate cancer.
Causes, Effects And Prevention of Global Financial Crisis In Viewpoint of Islam
Authors: Ghutai Gul , Ansari Sanaullah 
Published: November 2021

Abstract
Global financial crisis is not a new phenomenon. The world has witnessed financial crisis since many centuries. The repetition of global financial crisis reveals that global financial setup is not stable thus, prone to frequent financial crisis. However, zero interest rate policy has been launched by developed countries in order to offset the effects of global financial crisis but to date the issue of financial and monetary instability has not been overcome. Interest rate as the main component of financial setup has adversely affected the permanent solution to global financial crisis. The study is undertaken to analyze the effect of interest rate (riba) in propagation of global financial crisis and to analyze the alternate financial mechanism to prevent global financial and economic crisis on permanent basis. However, the qualitative research methodology is pursued to build a conceptual framework by applying inductive paradigm to address the issue of understanding the rationale behind the prohibition of interest based financial paradigm particularly in regard to Islamic perspective. The expected outcome suggests that man-made laws in order to subside divine laws in financial paradigm have given rise to financial, ethical and economic crisis. Global financial crisis is the outcome of easy access to credit, abundance of loans upon interest, speculation, greed as well as corruptive motives to exploit each other.
Factors Associated with Changes in the Objectively Measured Physical Activity among Japanese Adults: A Longitudinal and Dynamic Panel Data Analysis
Authors: Watanabe Daiki , Murakami Haruka , Gando Yuko , Kawakami Ryoko , Tanisawa Kumpei , Ohno Harumi , Konishi Kana , Sasaki Azusa , Morishita Akie , Miyatake Nobuyuki , Miyachi Motohiko 
Published: November 2021

Abstract
Background: Factors of dynamic changes associated with changes in the objectively measured physical activity have not been well understood. We aimed to 1) evaluate the longitudinal change in the physical activity trajectory associated with age according to sex and to 2) determine the dynamic changes factors associated with the change in physical activity-related variables across a wide age range among Japanese adults.Methods: This longitudinal prospective study included 689 Japanese adults (3914 measurements) aged 26–85 years, whose physical activity data in at least two surveys were available. Physical activity-related variables, such as intensity (inactive, light [LPA; 1.5 to 2.9 metabolic equivalents (METs)], moderate to vigorous [MVPA; ≥3.0 METs]), total energy expenditure (TEE), physical activity level (PAL), and step count, were evaluated using a validated triaxial accelerometer. The inactive times were calculated by subtracting the sum of sedentary (<1.5 METs) and non-wearing periods from 1440 minutes. Statistical analysis involved the latent growth curve models and random-effect panel data multivariate regression analysis. The covariates for multivariate analysis included the age, sex, region, body mass index, waist/hip ratio, comorbidity score, smoking status, alcohol intake, energy intake, diet quality score, hemoglobin, heart rate, hand grips, leg power, and trunk flexibility.Results: During a mean follow-up period of 6.8 years, physical activity was assessed 5.1 times in men and 5.9 times in women on average. The profiles for the inactive time, LPA (only men), MVPA, step count, PAL, and TEE showed clear curvature, indicating an accelerated rate of change around the age of 70. In contrast, other variables exhibited minimal or no curvature over the age span. The MVPA trajectory was positively associated with alcohol consumption, hand grips, leg power, and trunk flexibility, and negatively associated with age, local area, BMI, comorbidity score, and heart rate over time.Conclusions: Our results indicated that the physical activity trajectory showed clear curvature, accelerated rate of change around the age of 70, and determined physical health and fitness and BMI as dynamic changes factors associated physical activity changes. These findings may be useful to help support populations to achieve and maintain the recommended level of physical activity.
Predictors of neonatal mortality in Ghana: evidence from 2017 Ghana Maternal Health Survey
Authors: Adongo Emmanuel Ayire , Ganle John Kuumuori 
Published: November 2021

Abstract
Background
Neonatal mortality contributes about 45% of under-5 mortality globally; 35% in Sub-Saharan Africa; and over 50% of under-5 deaths in Ghana. Though there are existing studies on the determinants of neonatal mortality in Sub-Saharan Africa, limited population level analysis has been done in Ghana to understand the factors affecting neonatal mortality.
Objectives
The objective of the study was to examine the predictors of neonatal mortality in Ghana.
Method
Data from the 2017 Ghana Maternal Health Survey (GMHS) were analysed. The data used in the analysis included only responses from women who delivered live babies in the five years preceding the 2017 GMHS and the children lived for at least 28 days. A total of 10,624 respondents were included in the study after data cleaning. Descriptive statistical techniques (frequency and percentage distribution) were used to describe important background characteristics of the women included in the study. Pearson’s Chi-squares (χ2) test was used to assess association between the outcome (neonatal death) and independent variables. Multivariate logistic regression analysis was done to estimate odds ratios and control for potential confounders. Confidence level was held at 95%, and a p< 0.05 was considered statistically significant. All the data analysis was done using STATA 15.
Results
The prevalence of neonatal mortality was 1.8% i.e. 18 per 1000 live births. Three factors predicted neonatal mortality: ANC attendance, sex of baby, and baby being put on mother’s chest immediately after birth. Women with at least one ANC visit were less likely to experience neonatal mortality as compared to women with no ANC visit prior to delivery (AOR=0.11; CI=0.02-0.56, p=0.01). Baby girls were less likely (COR=0.68; CI=0.48-0.20; p=0.03) to die during the neonatal period as compared to boys and this did not change when potential confounders were controlled for in a multiple logistic regression model (AOR=0.68, CI=0.47-0.98; p=0.04). The odds of a baby dying within the neonatal period when a baby was not put on the mother’s chest immediately after birth were 2.5 times higher than those who were put on their mother’s chest immediately after birth (COR=2.46; CI=1.66-3.65, p=0.00).
Conclusion
Community level and sociodemographic factors were not significant predictors of neonatal mortality in this study. Rather, neonatal, and maternal characteristics did. Education on the importance of timely and adequate antenatal care should be intensified. Also, targeted social and behaviour change communication emphasizing the importance of immediate skin-to-skin kangaroo mother care to prevent neonatal hypothermia and promote successful breastfeeding should intensified.
Barrier Lyapunov Function-Based Fixed-Time FTC for High-Order Nonlinear Systems with Predefined Tracking Accuracy
Authors: Wang Xiaolin , Xu Jihui , Lv Maolong , Zhang Lei , Zhao Zilong 
Published: November 2021

Abstract
This article proposes a fixed-time adaptive fault-tolerant control methodology for a larger class of high-order nonlinear systems subject to full-state constraints and actuator faults. In contrast with the stateof-the-art results, the distinguishing feature of our control design consists in proposing a novel high-order tantype barrier Lyapunov function (BLF) which ensures state variables to be some asymmetric time-varying compact sets under tan-type constraints and expands the application range of tan-type BLF (i.e., from low-order to high-order, from symmetric time-invariant to asymmetric time-varying). Apart from this, the proposed control design ensures the tracking errors converge to specified residual sets within fixed-time and makes the size of the convergence regions of tracking errors adjustable a priori by means of a new BLF-based tuning function and a projection operator. A variable-separable lemma is delicately embedded into the control design to extract the control terms in a linear-like fashion which not only overcomes the difficulty that virtual control signals appear in a non-affine manner, but also solves the problem of actuator faults. Comparative simulations results finally validate the e ectiveness of the proposed scheme.
Devosia litorisediminis sp. nov., isolated from a sand dune
Authors: Park Sooyeon , Seo Min Ju , Kim Wonyong , Yoon Jung-Hoon 
Published: November 2021

Abstract
A Gram-negative, aerobic, non-motile, and rod-shaped bacterial strain, designated BSSL-BM10T, was isolated from a sand dune that was collected from the Yellow Sea, Republic of Korea. It was subjected to a polyphasic taxonomic study. 16S rRNA gene sequence analysis showed that strain BSSL-BM10T fell phylogenetically within the radiation comprising type strains of Devosia species. The 16S rRNA gene sequence of strain BSSL-BM10T shared sequence similarities of 98.2% with the type strain of D. naphthalenivorans and 93.5-97.7% with type strains of other Devosia species. ANI and dDDH values between strain BSSL-BM10T and type strains of 18 Devosia species were 71.0-78.4% and 18.8-21.5%, respectively. The DNA G+C content of strain BSSL-BM10T was 60.9% based on its genomic sequence data. Strain BSSL-BM10T contained Q-10 as the predominant ubiquinone and 11-methyl C18:1 ω7c, C18:1 ω7c, summed feature 3 (C16:1 ω7c and/or C16:1 ω6c), and C16:0 as its major fatty acids. Major polar lipids of strain BSSL-BM10T were phosphatidylglycerol and two unidentified glycolipids. Strain BSSL-BM10T showed distinguished phenotypic properties with its phylogenetic and genetic distinctiveness separated from recognized Devosia species. Based on data presented in this study, strain BSSL-BM10T should be placed in the genus Devosia. The name Devosia litorisediminis sp. nov. is proposed for strain BSSL-BM10T (= KACC 21633T = NBRC 115152T).
Chronic Enteropathy Associated with SLCO2A1-Associated Primary Hypertrophic Osteoarthropathy in Female Patients: A Case Report and Literature Review
Authors: Long Bangce , Tang Hui , Zhao Xueru , Yang Chao , He Tian , Zhang Wen , Tang Ming , Chen Jin , Wan Ping 
Published: November 2021

Abstract
This paper reports a case of chronic enteropathy associated with the SLCO2A1 gene (CEAS) combined with primary hypertrophic osteoarthropathy (PHO). The patient was a 25-year-old woman with a normal onset of puberty who was admitted to our hospital four times due to intractable oedema and anaemia. She had a history of hyperhidrosis since childhood, and her parents were close relatives (cousins). Enteroscopy revealed stenotic ulcers on the ileocecal valve and the terminal ileum. Computed tomography enterography (CTE) and magnetic resonance enterography (MRE) showed segmental thickening of the ileum and terminal intestinal wall and centripetal narrowing of some intestinal cavities. MRE also showed a marked "comb sign" in the adjacent mesentery, and X-rays of both lower limbs showed thickening of the tibiofibular cortex. The CEAS pathogenic genes were screened by whole exome sequencing, and a homozygous missense mutation of p. Gly222Asp (c.664G>A) was found in the fifth exon of the SLCO2A1 gene, which was verified by Sanger sequencing. In conclusion, the patient was identified as CEAS with PHO associated with a SLCO2A1 gene mutation, but the patient is a young woman, which has rarely been reported in previous studies. In addition to reporting her case, the relevant literature was reviewed to improve clinicians' understanding of diseases associated with the SLCO2A1 gene.
Transport of Polymer-Coated Metal-Organic Framework Nanoparticles in Porous Media
Authors: Nune Satish K. , Miller Quin R.S. , Schaef H. Todd , Jian Tengyue , Song Miao , Li Dongsheng , McGrail B. Peter 
Published: November 2021

Abstract
Injecting fluids into deep underground geologic structures is a critical component to development of long-term strategies for managing greenhouse gas emissions and facilitating energy extraction operations. Recently, we reported that metal-organic frameworks are low-frequency absorptive acoustic metamaterial that may be injected into the subsurface enhancing geophysical monitoring tools used to track fluids and map complex structures. A key requirement for this nanotechnology deployment is transportability through porous geologic media without being retained by mineral-fluid interfaces. Flow-through column studies were used to estimate transport and retention properties of five different polymer-coated MIL-101(Cr) nanoparticles in siliceous porous media. Nanoparticle transport experiments revealed that nanoparticle surface characteristics play a critical role in nanoparticle colloidal stability and as well the transport.
Mitogenome of the Extinct Desert ‘Rat-Kangaroo’ Times the Adaptation to Aridity in Macropodoids
Authors: Westerman Michael , Loke Stella , Tan Mun Hua , Kear Benjamin 
Published: November 2021

Abstract
The evolution of Australia’s distinctive marsupial fauna has long been linked to the onset of continent-wide aridity. However, how this profound climate change event affected the diversification of extant lineages is still hotly debated. Here, we assemble a DNA sequence dataset of Macropodoidea — the clade comprising kangaroos and their relatives — that incorporates a complete mitogenome for the Desert ‘rat-kangaroo’, Caloprymnus campestris. This enigmatic species went extinct nearly 90 years ago and is known from a handful of museum specimens. Caloprymnus is significant because it was the only macropodoid restricted to extreme desert environments, and therefore calibrates the group’s specialisation for increasingly xeric conditions. Our robustly supported phylogenies nest Caloprymnus amongst the bettongs Aepyprymnus and Bettongia. Dated ancestral area optimisations further reveal that the Caloprymnus-Bettongia lineage originated in nascent arid zone settings from the later-middle to early-late Miocene, ~12 million years ago (Ma), but subsequently dispersed into mesic habitats during the Pliocene and Pleistocene. This coincides with ancestral divergences amongst kangaroos in disparate woodland-forest and shrubland settings, but predates their adaptive radiation into proliferating grasslands during the late Miocene to Pliocene, after ~7 Ma. We thus demonstrate that protracted changes in both climate and vegetation likely staged the emergence of modern arid zone macropodoids.