bluuebunny/crossref_metadata_2025_split huggingface dataset:
Argon plasma coagulation for the treatment of chronic radiation proctitis – real-world data from Indonesian National Cancer Center
Authors: Siregar Lianda , Loho Imelda Maria , Waspodo Agus Sudiro , Swadari Rahmanandhika , Maharani Benedicta Audrey 
Published: September 2021

Background: This study aimed to evaluate the endoscopic features and clinical outcome of patients with chronic radiation proctitis (CRP) at one year after argon plasma coagulation (APC) treatment. Method: Between March 2016 and September 2019, a total of 48 female patients with CRP were treated with APC and their medical records were retrospectively reviewed. APC treatment was done every 3 to 54 weeks, with a median of 8 weeks. Number of APC was decided by the treating physician according to the severity of illness. Endoscopic and clinical features at one year after the final APC were recorded as the effectiveness of APC.Results: Of 48 patients, 26 patients were included in this study. Number of APC sessions varied between 1 to 5 sessions of APC for each patient. Of 26 patients, 22 patients achieved clinical improvement and four patients did not achieve clinical improvement at one year after the last APC session. Of the four patients who failed to achieve clinical improvement, two patients underwent surgery, one patient had occasional mild rectal bleeding, and one patient required regular transfusion. Of 22 patients with clinical improvement at one-year after the last APC, improvement of endoscopic features was found in 20 patients. Of four patients who did not achieve endoscopic improvement, diagnostic colonoscopy showed telangiectasis of more than 50% of rectal surface in 1 patient, presence of blood in 2 patients, and presence of ulceration of 1 cm in 1 patient.Conclusion: APC is an effective treatment option for CRP.
Clinical and genetic factors associated with the risk of recurrent ischemic events in patients with stable stenocardia
Authors: Pronko T. P. , Snezhitskiy V. A. , Gorchakova O. V. , Gladkiy M. L. , Kapytski A. V. 
Published: September 2021

The aimof the study was to assess the clinical and genetic factors associated with the risk of recurrent ischemic events in patients with stable stenocardia (SS).Materials and methods.A total of 100 patients with SS were examined and followed-up for 15.3±8.3 months. The patients were divided into subgroups (SG): SG1 (n=51) – persons without events, SG2 (n=49) persons with recurrent ischemic events (hospitalization due to the development of pain syndrome, re-stenting due to stent restenosis, myocardial infarction, cerebral infarction and death from cardiovascular causes), SGB (n=11) – persons with «major» recurrent ischemic events (re-stenting due to stent restenosis, myocardial infarction, cerebral infarction and death from cardiovascular causes) , SGG (n=89) – persons without «major» events. The obtained survey data (general clinical, aggregometry, polymor phism of genes of platelet fibrinogen receptor ITGB3 (T1565C), platelet collagen receptor ITGA2 (C807T), ADP platelet receptor P2RY12, H1/H2 (T744C)) were analyzed using the STATISTICA 10.0 software.Results.In SG2, men predominated (χ2=9.2; p<0.01), past MI was more common (χ2=4.8; p<0.05), more stents were implanted (2.4±1.9 versus 1.7±1.1, p<0.05), TRAP-test values were higher (p<0.05) compared to SG1. In SGB, greater number of stents were implanted (3.1±2.2 versus 1.61±1.57, p<0.05), the carriage of the TC genotype of the ITGB3 gene was more common, (p<0.05), a combination of gene mutations ITGB3 and P2RY12 was more common, (p<0.05) compared to SGG. A logistic regression equation was constructed, including the presence of diabetes mellitus, the number of platelets in the blood test, the ASPI-test values, the carriage of the 1565C allele of the ITGB3 gene, the number of stents implanted, which makes it possible to determine the likelihood of developing «major» recurrent ischemic events with a cut-off threshold LP₀=0.0965, with sensitivity – 81.82 %, specificity – 78.48 %, overall accuracy – 78.89 %.Conclusions.The factors associated with the development of recurrent ischemic events are: male sex, previous MI, a greater number of implanted stents, and high TRAP-test values. The factors associated with the development of recurrent «major» ischemic events are: a greater number of implanted stents, carriage of the TC genotype of the ITGB3 gene, carriage of a combination of mutations of the H1/H2 polymorphic locus of the P2RY12 gene and the T1565C polymorphic locus of the ITGB3 gene, diabetes mellitus, the number of platelets in blood test, ASPI-test values.
Predictors of myocardial reperfusion syndrome: a modern view of the issue and current problems. Part 2: no-reflow phenomenon (literature review)
Authors: Khubulava G. G. , Kozlov K. L. , Shishkevich A. N. , Mikhaylov S. S. , Bessonov E. Yu. , Tokarev P. A. , Pachkov D. A. , Bobrovskaya E. E. 
Published: September 2021

Despite the fact that the phenomenon of unrecovered coronary blood flow (no-reflow) has long been known, there is still no unanimous opinion about the predictors and, accordingly, the risk groups for its occurrence. This prevents predicting the further course of the disease and investigating the effectiveness of therapeutic and surgical methods for preventing the consequences of reperfusion in patients with ST-segment elevation myocardial infarction, which in turn worsens the postoperative and long-term prognosis in this group of patients. We used the search engines E-library, Google Scholar and Pubmed to search for studies on this issue. The article presents and analyzes research data covering the predictors of the no-reflow phenomenon. The difficulties in identifying them are also described, the issue of a diagnostic approach ans sampling for research is raised. A review of studies dedicated to the identification of predictors of the no-reflow phenomenon using optical coherence tomography and intravascular ultrasound is given.
Mad Insight
Authors: Dumaresque Renee 
Published: September 2021

This poem is informed by the relationships between gender, race, chronic pain, hysteria, and the role of dominant discourses in shaping interpretations of bodily and psychic pain. Drawing on my lived experience as a non-binary person with chronic vulvar pain, or vulvodynia, I challenge the psychiatrization of chronic pain and propose hysteria as a potential state of resistance and refusal (Dumaresque, 2019). I weave fog throughout this poem as a metaphor that captures pain, madness, and perception. Fog symbolizes disruption and disorientation; yet, fog also gestures to the potentiality of being displaced from normative insight (Bruce, 2017). I engage William Connolly’s (2010) reading of perception as formed through discipline to think through the silent but subversive waves of knowledge and power that carve the lenses through which we story ourselves and others (Erickson, 2016). As Thomas King (2003) writes, “the truth about stories is that’s all we are” (p. 32). This poem is situated in a reading of madness and hysteria as sites of affective protest (Dumaresque, 2019). I ask, what can be resourced from our becoming un-hinged? This poem contributes to mad knowledge that is intersectional and in-service to disrupting medical and psychiatric violence, whiteness, hetero/cis-governance, and “compulsory able-bodymindedness” (Sheppard, 2018, p. 59).
Os desafios dos cuidados paliativos na atenção primária à saúde
Authors: Ordonho Laura Comeli , Dias Isadora Correia , Bernardino Julia de Oliveira , Almeida Jullyana Lopes , Junior Lucio Mendes , Paula Mariana Martins de Mello , Quintão Marina Perigolo Barros , Miranda Nayara Lima de , Mendes Talita de Oliveira Côrtes , Corrêa Mônica Isaura 
Published: September 2021

Objetivo: Revisar e descrever o papel da Atenção Primária em Saúde (APS) no manejo ao paciente em Cuidado Paliativo (CP), a partir da análise da literatura atual sobre o tema. Revisão bibliográfica: O CP está associado à melhora da qualidade de vida de pacientes que enfrentam doenças graves e de seus familiares. Nesse contexto, a APS é vista como o melhor local para a prática do CP, uma vez que tem como objetivo o cuidado integral do paciente e sua família, a partir de uma relação mais próxima com a equipe de saúde. Entretanto, o CP ainda é um desafio para o Sistema Único de Saúde devido, principalmente, à alta demanda decorrente do envelhecimento populacional e aumento dos agravos crônicos, a não disponibilidade de recursos tecnológicos e humanos capacitados e a escassez de programas governamentais específicos. Considerações finais: É de suma importância que haja a implementação de diretrizes e protocolos de saúde voltadas para desenvolver os CP, maior capacitação profissional e estímulo para maior consciência social e envolvimento da comunidade como um todo com as questões de saúde da população.
Assessment of The Difficulty of Mathematics High-Level Reasoning Using Focus Group Discussion and Program Item Approaches
Authors: Rukli Rukli , Ma'rup Ma'rup 
Published: September 2021

This study aims to estimate the difficulty level of high-level reasoning math problems by comparing the estimated difficulty level of the Focus Group Discussion (FGD) approach and the Iteman program. The estimation of the FGD approach uses a semantic differential scale on a scale of 1-7, while the Iteman program uses version 4.0. The study used a quantitative-comparative approach involving 79 FGDs of students and teachers of SMP/MTs in Soppeng Regency. Each FGD consisted of four people, one teacher and three students of class VIII. The comparative of difficulty level using Scheffe test with a significance level of 0.05. The results showed that the average level of difficulty in the FGD approach had significant similarity with the average level of difficulty in the output of the Iteman program approach. This means that the estimated level of difficulty of the FGD examinees has a similarity with the output of the Iteman program from the response data of the FGD examinees. This shows that examinees from FGD in assessing the level of difficulty of high-level reasoning questions can be the teacher’s choice in schools other than the Iteman program.
Diagnostic Study of Salmonella typhimurium in Patient and Cattle
Authors: Habeeb Zainab Sami , AL-Shawi Amil majid , Fathi Muniem M. 
Published: September 2021

A total of (150) stool samples were collected from patient with diarrhea in Baghdad hospital and Al - Thahab. Al-Aboiath village. A total of (27) isolates were identified as member of the genous Salmonella, Serotype typhimurium of a percentage of 18 % of the total samples.Another(150) stool sample were collected from suspected calves and cows in some of Baghdad villages and dairy cattle stations
The identified isolates as member of Salmonella,serotype typhimurium were (7) at a percentage of 4.5% of the total taken samples. The study extend from December 2001 till May 2002.
Different biochemical tests were applied to differentiate the isolates from other enteric micro organism, Including the classical and newly introduced methodologies(i.e.,api 20E) in addition to the type and serotype determination using standard mono specific and polyvalent antisera. All the isolates showed no changes in there characteristic features.
Deteksi Dini Pencegahan CA Servik dengan Pemeriksaan IVA Pap Smear di Rumah Cantik Almira Beauty Desa Tunggalpager Kec. Pungging Kab. Mojokerto Bekerja Sama dengan PKBI Kabupaten Mojokerto
Authors: Idayanti Titiek , Umami Siti Fithrotul , Zubaidah Risna , Anggraeni Widya 
Published: September 2021

Kanker serviks merupakan keganasan yang berasal dari serviks dan merupakan salah satu penyebab kematian pada wanita. Penyebab dari kanker serviks adalah infeksi Human Vapiloma Virus (HPV). HPV ditularkan melalui hubungan seksual dan ditemukan pada 95% kasus kanker serviks. Data dari WHO (World Health Organization), kanker merupakan penyebab kematian nomor 2 di dunia. Kurangnya pengetahuan wanita usia subur tentang kanker serviks dapat berdampak pada tidak adanya perilaku untuk melakukan pemeriksaan dini dengan tindakan IVA. Dampak kanker serviks jika tidak segera dilakukan pemeriksaan pada organ reproduksi serviks beresiko keadaan kesehatannya telah menjadi kritis atau penyakit sudah mencapai pada tahap stadium lanjut sehingga dapat berunjung pada kematian.
Kegiatan pengabdian kepada masyarakat ini dilakukan dengan tujuan membantu semua wanita usia subur yang ada di Desa Tunggalpager Kecamatan Pungging Kabupaten Mojokerto untuk dapat menditeksi secara dini adanya kelainan atau kondisi yang menunjukkan adanya tanda – tanda kearah kanker servik dengan melakukan pemeriksaan IVA dan Pap Smear. Kegiatan ini bertempat di RumahCantik Almira Beauty, yang di ikuti sejumlah 38 peserta. Sebelum pasien dilakukan pemeriksaan IVA & Pap Smear, pasien dikumpulkan untuk diberikan edukasi tentang pengertian CA Servik, factor penyebabnya dan bagaimana cara mencegahnya. Setelah itu, setelah itu peserta di bagi 2 kelompok, masing – masing kelompok terdiri dari 14 oarang. Dari 14 peserta yang dilakukan pemeriksaan IVA didapatkan hasil 3 peserta terdapat kelainan servik yang dicurigai kea rah CA Servik. Sedangkan 14 peserta yang dilakukan pemeriksaan Pap Smear didapatkan hasil 6 pasien mengalami vaginitis.
Keberhasilan dari kegiatan ini diharapkan dengan mengetahui secara dini hasil pemeriksaan IVA Pap Smear, dan telah mendapatkan edukasi tentang CA Servik, diharapkan ibu – ibu aau peserta yang ikut dapat menjaga kesehatan reprodukasinya dan menerapakan pola hidup bersih dan sehat agar dapat meminimalkan dan mencegah terjadinya CA Servik. Setalah memahami pentingnya diteksi dini CA Servik dengan melakukan pemeriksaan IVA Pap Smear ini, diharapkan pula semua wanita usia subur tidak perlu takut untuk melakukan pemeriksaan IVA Pap Smear dan dapat melakukannya secara rutin setiap 1 tahun sekali.
Essay Review: Evidence-Based Analysis of the COVID Pandemic
Authors: Bauer Henry 
Published: September 2021

This short book suggests plausible answers to much of what has seemed inexplicable or unbelievable about what governments, the World Health Organization, and popular media have disseminated about the officially declared global pandemic.
The author is a recently graduated Swedish physician who recognized even during his training that many of the generally accepted shibboleths about medical matters are not evidence-based; are often, in fact, contrary to the available evidence.
Irrespective of his suggestions about COVID, several points in this book are important for everyone to know:

Modern medicine focuses on the handling of emergencies but says “extremely little about how to avoid chronic disease and maximize long term health” (p. 7).
More than half of the widely accepted recommendations about nutrition are nonsense, without any basis in solid evidence (p. 8): to eat more fruit, fish, vegetables, whole-grain cereals, and less salt, saturated fat, or meat.
Much purportedly scientific medical information stems from inappropriate use of surrogate endpoints and improper statistical analyses (pp. 34–39): The usual criterion for statistical significance (p ≤ 0.05) is arbitrary and very weak. The typical marketing ploy of citing relative rather than absolute risks is highly misleading (pp. 40–46).

How deadly is COVID?
Profile of SGOT And SGPT Level Check in Pulmonary Tuberculosis Patients
Authors: Chairini Siti , Priyatno Djoko 
Published: September 2021

Liver disfunction is characterized by increased levels of SGOT and SGPT. The mechanism of liver disfunction by anti-tuberculosis drug (ATD) is not yet clearly known, but several research mention the occurrence of hepatotoxicity which caused by direct effect or through the complex production of drug enzyme which have consequences in cell disfunction as well as membrane disfunction. Hepatotoxicity due to ATD does not occur in each patient, but it could cause liver injury. research objective to find out the description of examination of SGOT and SGPT levels in patients of pulmonary tuberculosis. The research type was descriptive using medical records data and laboratory data of RSUP patients of pulmonary TB in January-March 2020. Research results : the normal SGOT levels in men 6-33 U/L as much as 63,33%, and SGOT normal 50-66 U/L as much as 2,35%. The normal SGOT levels in women 10-25 U/L as much as 25,88%, and SGOT normal in women 15-63 U/L as much as 8,24%. The normal SGPT levels in men 3-43 U/L as much as 62,35%, and SGPT normal 55-65 U/L as much as 3,53%. The normal SGPT levels in women 7-29 U/L as much as 34,12%. Hepatotoxicity based on SGOT levels as many as 9 people (10,59%), namely 2 men (elderly and old man) and 7 women (adolescent, adult, and elderly). Hepatotoxicity based on SGPT levels as many as 3 people (3,53%) in elderly and old man.
Weed Control in Pepper
Authors: Stall William M. , Gilreath James P. 
Published: September 2021

Revised! HS-199, a 5-page fact sheet by William M. Stall and James P. Gilreath, describes a weed control program that integrates chemical, mechanical, and cultural methods and provides a table of listing herbicides available to growers for chemical weed control of pepper. This publication updates the 2003 tables to reflect current recommendations. Published by the UF Department of Horticultural Sciences, October 2006.
HS199/WG034: Weed Management in Pepper (ufl.edu)
ПИТАННЯ ЗБРОЙНОЇ БОРОТЬБИ В ДІЯЛЬНОСТІ ОУН НА ЗАПОРІЖЖІ (1940–1943 РР.)
Authors: Щур Юрій 
Published: September 2021

У статті проаналізовано проблему підготовки членів Організації українських націоналістів, які діяли на території Запорізької області, до загальноукраїнського повстання. Висвітлено діяльність націоналіс- тичних організацій, зокрема й у військових частинах Червоної армії. З’ясовано, що серед пріоритетів націоналістичного підпілля на території Запорізької області були збір й накопичення зброї, а також створення в перспективі партизанських загонів. Хронологічно рамки дослідження прив’язані до появи перших осередків ОУН у регіоні (нижня межа) та до піку в діяльності організованого націоналістичного підпілля в області (верхня межа).
Ключові слова: Запорізька область, Мелітополь, НКВС, НКДБ, Організація українських націоналістів.
ПРАВО НА СПОВІДЬ: НОТАТКИ ВІЙСЬКОВОГО КАПЕЛАНА
Authors: Журавльов Микола , Грицюк Валерій 
Published: September 2021

Рецензія на науково-популярне видання: Присяжний Д. А. «Зі зброєю в руках — із молитвою на вустах». К.: Ярославів Вал, 2019, 128 с.
Psychology of Da’wah Impact on Balanced Personality Among Private Young Adult Higher University in Malaysia
Authors: Idris Saleha , Mohd Jailani Mohd Rushdan , Mahyuddin Muhammad Khairi , Ab. Rahman Othman 
Published: September 2021

Youth adulthood today, should be taught to have a balanced personality to succeed both in the world and hereafter. Psychology of da'wah and balance personality are dynamic internal systems which form an individual's pattern of action, thought and feeling. Youth adulthood should practice moderate Islamic lifestyle, so that the knowledge gained is competent for the purpose to achieve the pleasure of Allah. Thus, the objective of this study is to examine the impact psychology da’wah on balanced personality. The research hypothesis is tested with a sample of young adulthood in private universities and through structural equation modelling using SMART-PLS software. As a result, the study verifies the impact of the psychology da’wah on balanced personality. Thus, psychology Da’wah approach can be applied in counselling in managing psychological problems especially related to the personality of Muslim students. It may also assist students in having a greater sense of self-efficacy while in university and increase the level of balanced personality.
Organ Transplant in Present-Day Japan: Reasons behind Low Numbers of Deceased Donors
Authors: Czekajewska Justyna Magdalena , Jaworowicz-Zimny Aleksandra 
Published: September 2021

According to the International Register of Organ Donation and Transplantation, Japan is one of the countries with the lowest number of registered deceased donors. In 2019, Japan was ranked 61st out of 70 countries. The authors of this article have decided to explore the reasons for this phenomenon. In the first part of the work, religious influences (Shinto and Buddhism), the tradition of gotai manzoku, the importance of altruism and the family in the perception of death and organ transplantation by the Japanese are considered. The second part of the article presents the arguments of Alan Shewmon, who believes that brain death is not death in the biological sense. Undermining the brain’s death criterion raises doubts concerning death of patients in irreversible coma, what in result discourages transplantology in Japan. In the third part, the authors compare the results of JOTN, IRODaT and the Fact Book of Organ Transplantation 2018 in Japan from 2010 to 2018. The aim of the article is to explain the cultural determinants of transplantology in Japan, taking into account the influence of philosophical and bioethical aspects of human death.
Nutritional status of children with undernutrition
Authors: Keleinikova A. V. , Titova O. N. , Matinyan I. A. , Taran N. N. , Zubovich A. I. , Strokova T. V. 
Published: September 2021

Objective. To assess nutritional status of children with undernutrition without chronic diseases.Patients and methods. Eighty one children without chronic diseases and with undernutrition aged 3 months to 17 years and 2 months, 41 boys (50.6 %), 40 girls (49.4 %), were examined. The anthropometry was assessed by WHO criteria. The complete blood count (n = 69), blood biochemistry (n = 62), insulin level and vitamin status were examined. Bioelectric impedance analysis (n = 58) and indirect respiratory calorimetry (n = 28) were performed. The food intake was assessed in 28 patients.Results. Mild undernutrition was diagnosed in 35 (43.2 %) children, moderate - in 30 (37 %), severe - in 16 (19,8 %) children. The stunting (Z-score height to age < -2) was revealed in 3 (3,7 %) children. Anemia was found in 4 (5.8 %) children, absolute lymphopenia - in 2 (2.9 %), hypoproteinemia in 8 (12.9 %), hypoalbuminemia - in 1 (1.5 %), hypocholesterolemia - in 7 (11.3 %), hypercholesterolemia - in 6 (9.7 %) children. None of children had hypoglycemia. Insulin was decreased in 9 (15.5 %) children. Deficiency of vitamin D was found in 11 (13.6 %) patients. Decrease of fat mass was found in 52 (89,7 %) patients, muscle mass - in 42 (72.4 %), active cell mass - in 18 (31 %), protein - in 37 (63.8 %), minerals - in 41 (70.7 %), total body water - in 36 (62.1 %) patients. Decrease of the phase angle (<4.4) was recorded in 13 (22,4 %) children. Resting energy expenditure was normal in 12 (42,8 %) patients. Carbohydrate oxidation rate was decreased in 20 (71,4 %) children, fat oxidation rate was increased in 15 (53,6 %), protein oxidation rate was normal in 15 (53,6 %) children. The food intake was characterized by low energy intake in 21 (75 %) children. Deficiency of protein, fat and carbohydrate intake were found in 42.9, 60.7 and 82.1 % patients, respectively. Low energy intake due to all macronutrients deficiency was revealed in 35.7 % children.Conclusion. Most children with undernutrition without chronic diseases have a decrease in fat and muscle body components, low energy value of diet and imbalance of macronutrients. Changes in resting metabolism were also revealed.