bluuebunny/crossref_metadata_2025_split huggingface dataset:
Awake Prone Positioning in Nonintubated Spontaneous Breathing ICU Patients with Acute Hypoxemic Respiratory Failure (PRONELIFE) – Protocol for a Randomized Clinical Trial
Authors: Morales-Quinteros Luis , Schultz Marcus J , Neto Ary Serpa , Antonelli Massimo , Grieco Domenico L , Roca Oriol , Juffermans Nicole , Blanch Lluis , De Haro Candelaria , De Mendoza Diego , Camprubi-Rimblas Marta , Artigas Antonio 
Published: December 2021

Abstract
BackgroundIt is uncertain whether awake prone positioning can prevent intubation for invasive ventilation in spontaneous breathing critically ill patients with acute hypoxemic respiratory failure. Awake prone positioning could benefit these patients for various reasons, including a reduction in direct harm to lung tissue, and prevention of tracheal intubation related complications.Design and MethodsThe PRONELIFE study is an investigator–initiated, international, multicenter, randomized clinical trial in patients who may need invasive ventilation because of acute hypoxemic respiratory failure. Consecutive patients admitted to participating ICUs are randomly assigned to standard care with awake prone positioning, versus standard care without awake prone positioning. The primary endpoint is a composite of tracheal intubation and all–cause mortality in the first 14 days after enrolment. Secondary endpoints include time to tracheal intubation and effects of awake prone positioning on oxygenation parameters, dyspnea sensation, and complications. Other endpoints are the number of days free from ventilation and alive at 28 days, total duration of use of noninvasive respiratory support, total duration of invasive ventilation, length of stay in ICU and hospital, and mortality in ICU and hospital, and at 28, 60, and 90 days. We will also collect data regarding the tolerance of prone positioning.DiscussionThe PRONELIFE study is amongst the first randomized clinical trials investigating the effect of awake prone positioning on intubation rate in ICU patients with acute hypoxemic failure from any cause. The PRONELIFE study is sufficiently sized to determine the effect of awake prone positioning on intubation for invasive ventilation––patients are eligible in case of acute hypoxemic respiratory failure without restrictions regarding etiology. The PRONELIFE study is a pragmatic trial in which blinding is impossible––however, as around 35 ICUs worldwide will participate in this study, its findings will be highly generalizable. The findings of the PRONELIFE study has the potential to change clinical management of patients who may need invasive ventilation because of acute hypoxemic respiratory failure.Trial registrationISRCTN, ISRCTN11536318. Registered 17 September 2021, https://www.isrctn.com/ISRCTN11536318The PRONELIFE study is registered at clinicaltrials.gov with reference number NCT04142736 (October, 2019).
A search for a stochastic archetype of quantum probability
Authors: Jenkins Tim C 
Published: December 2021

Abstract
Superposed wavefunctions in quantum mechanics lead to a squared amplitude that introduces interference into a probability density, which has long been a puzzle because interference between probability densities exists nowhere else in probability theory. In recent years, Man’ko and coauthors have successfully reconciled quantum and classic probability using a symplectic tomographic model. Nevertheless, there remains an unexplained coincidence in quantum mechanics, namely, that mathematically, the interference term in the squared amplitude of superposed wavefunctions gives the squared amplitude the form of a variance of a sum of correlated random variables, and we examine whether there could be an archetypical variable behind quantum probability that provides a mathematical foundation that observes both quantum and classic probability directly. The properties that would need to be satisfied for this to be the case are identified, and a generic hidden variable that satisfies them is found that would be present everywhere, transforming into a process-specific variable wherever a quantum process is active. Uncovering this variable confirms the possibility that it could be the stochastic archetype of quantum probability.
POLÍTICAS HABITACIONAIS NACIONAIS: OS DESAFIOS AO DIREITO DE MORADIA NOS ARRANJOS INSTITUCIONAIS DO PROGRAMA MINHA CASA MINHA VIDA
Authors: De Moraes Braga Junior Sergio Alexandre 
Published: December 2021

O presente trabalho tem como tema o enfrentamento dos desafios ao direito à moradia com foco em políticas habitacionais nacionais. Nesse sentido, tem como objetivo analisar os arranjos institucionais no âmbito do programa habitacional “Minha Casa Minha Vida” sob o viés da ampliação da participação nesse programa e da viabilização do alcance dos objetivos propostos. Tal exame considerará a inserção do referido programa no contexto da organização jurídico-institucional da política urbana em âmbito nacional. A metodologia seguirá o método indutivo e revisão da bibliografia e dos atos normativos relevantes ao tema. De início, situar-se-á enquanto política pública o programa “Minha Casa Minha Vida” e a inclusão da moradia entre o rol dos direitos fundamentais após a emenda constitucional nº 26/2000. Em seguida, enfatizar-se-á o empenho legislativo no sentido de garantir o direito à moradia, com vistas à harmonização entre os direitos individuais e coletivos e os processos de desenvolvimento econômico e preservação do meio-ambiente, enfatizando o papel do Estatuto das Cidades na consolidação desse direito fundamental. Avalia-se, como resultado, como a dinâmica do programa habitacional em questão lida com os fenômenos da cidade ilegal e da exclusão social e com as demandas advindas dos movimentos sociais relacionados à moradia, de forma a tecer conclusão acerca do grau de êxito desse programa no sentido de contribuir para a garantia e fortalecimento do direito à moradia no contexto pátrio.
Covid-19 pandemisinde genel hastane acil servisine başvuran intihar girişimlerinin incelenmesi
Authors: YENİ ELBAY Rümeysa , EROL Fatma Nur 
Published: December 2021

Amaç: Çalışmanın amacı Covid-19 pandemisinde genel hastane acil servisine başvuran intihar girişimlerini sosyodemografik ve klinik özellikleri açısından incelemektir.Yöntem: Çalışma, 01 Şubat 2021- 31 Temmuz 2021 tarihleri arasında genel hastane acil servisine intihar girişimi ile başvuran hastaların geriye dönük tıbbi kayıtları incelenerek yapılmıştır. Bulgular: İntihar girişimi ile başvuran 94 hastanın %59,4’ü kadın, %34‘ü çalışmayan, %52,1’i bekârdır. Hastaların yaş ortalaması 35.11±14.19’dur. Hastaların 36’sı daha önce intihar girişiminde bulunmuştur. İlaç doz aşımı (%86,2) en sık kullanılan intihar yöntemidir. Bunu kendini kesme (%12,8) ve sıçan zehri (%1,1) takip eder. Başvuranların çoğu (%58,5) psikiyatri poliklinik takibi ile taburcu edilmiş, %27,6’sı psikiyatri servisine yatırılmış, %13,3’ü psikiyatrik tedaviyi reddetmiştir. En sık başvuran yaş grubu 25-34 (%41,5)’tür. Vakaların yarısından fazlasının (%54,3) daha önce psikiyatrik öyküsü bulunmamaktadır. Kadın ve erkek hastalar arasında psikiyatrik tanı varlığı, önceki girişim sayısı, kullanılan yöntem ve değerlendirme sonrası psikiyatri servisine yatış gereksinimi açısından fark yoktur.Sonuç: Çalışmada Covid-19 döneminde intihar girişimlerinin cinsiyet, medeni durum, çalışma durumu, kullanılan yöntem ve girişim sayısı açısından pandemi öncesi döneme göre literatürden farklılık göstermediği görüldü. Ancak mevcut örneklemimizde yaş aralığı daha yüksekti ve daha önce psikiyatrik öyküsü olmayan daha fazla hasta vardı. Bu bulgular Covid-19 pandemisi döneminde ruh sağlığı hizmetlerine erişimin kolaylaştırılmasının önemini ortaya koymaktadır.
Assessment of Iodofolic Supplementation on Thyroid Function in Pregnant
Women with Iodine Sufficient Status and their Infants in Birjand
Authors: Farkhondeh Tahereh , Samarghandian Saeed , Rezaei Maryam , Ataei Naeemeh , Zarban Asghar , Mobasher Nahid 
Published: December 2021

Background:
Maintaining iodine at sufficient levels is necessary throughout the pregnancy
to prevent adverse outcomes in infants. This study aimed to assess iodofolic supplementation's
impact on thyroid function in women at the end of the third trimesters of gestation.

Methods:
This case-control study was conducted on 130 pregnant women in the Birjand, east of
Iran, during the period from August 2017 to February 2019. We assessed iodofolic supplementation
effect in the women at the first trimesters of gestation and followed them at the end of the third
trimesters and also their infants on days 3-5. Serum samples were obtained from women and infants
for measuring levels of thyroid-stimulating hormone (TSH). Urinary iodine concentration
(UIC) was also determined at the end of the third trimester.

Results:
The median serum TSH concentration in the folic acid consumed group (3.26 ± 1.91) did
not significantly differ from another group (2.98 ± 1.41), (p = 0.68). There is also no considerable
difference in the mean serum TSH concentration between infants born from mothers who consumed
folic acid in the first trimester of pregnancy and another group (p = 0.50). The TSH concentration
in all infants was below 5 μM/L. The significant difference in the mean of UIC was also not
observed between pregnant women in the folic acid consumed group (188.02 ± 105.38) and iodofolic
consumed group (225.77 ± 130.26), (p = 0.13).

Conclusion:
Iodine intake in our study was sufficient according to the WHO recommendation and
idofolic supplementation was not emphasized.
Application of Theory in Chronic Pain Rehabilitation Research and Clinical Practice
Authors: Uddin Zakir , MacDermid Joy C. , Hegazy Fatma A. , Packham Tara L. 
Published: December 2021

Introduction:
Chronic pain has multiple aetiological factors and complexity. Pain theory helps us to guide and organize our thinking to deal with this complexity. The objective of this paper is to critically review the most influential theory in pain science history (the gate control theory of pain) and focus on its implications in chronic pain rehabilitation to minimize disability.

Methods:
In this narrative review, all the published studies that focused upon pain theory were retrieved from Ovoid Medline (from 1946 till present), EMBAS, AMED and PsycINFO data bases.

Results:
Chronic pain is considered a disease or dysfunction of the nervous system. In chronic pain conditions, hypersensitivity is thought to develop from changes to the physiological top-down control (inhibitory) mechanism of pain modulation according to the pain theory. Pain hypersensitivity manifestation is considered as abnormal central inhibitory control at the gate controlling mechanism. On the other hand, pain hypersensitivity is a prognostic factor in pain rehabilitation. It is clinically important to detect and manage hypersensitivity responses and their mechanisms.

Conclusion:
Since somatosensory perception and integration are recognized as a contributor to the pain perception under the theory, then we can use the model to direct interventions aimed at pain relief. The pain theory should be leveraged to develop and refine measurement tools with clinical utility for detecting and monitoring hypersensitivity linked to chronic pain mechanisms.
Mineral Density and Markers of Bone Remodelling in Young Athletes in Response to Weightlifting Exercise: A Pilot Study
Authors: Reyes Fernando B. , Enríquez Rogelio R. , Brown Julio M. , S. Sainz José Andre-í , Méndez Estrada Rosa O. , V. Valle Rosa Consuelo , Dosamantes Armando C. , S. Sainz Héctor Manuel 
Published: December 2021

Background:
Weightlifting is a practice that exerts a high degree of pressure on the skeleton when supporting large loads of weight. The practice of exercise contributes by improving bone mineral density (BMD) and can prevent problems associated with low BMD.

Objective:
The objective of the present study was to determine BMD and measure bone turnover using blood markers in weightlifting athletes in response to exercise.

Methods:
The study included 16 athletes and 16 controls of both sexes in the range of 18 to 22 years old. BMD was determined at the femoral neck, hip, lumbar spine, and Total Mineral Density (TMD). The value of the total mineral density (TMDV) was obtained from the sum of the BMD of the evaluated regions. Bone formation and resorption in blood were evaluated by Alkaline Phosphatase (ALP) and Acid Phosphatase (ACP), respectively. In addition, the concentration of urea and Creatine Kinase (CK) were determined.

Results:
The mean BMD of the lumbar spine and TMDV was of 1.2 g/cm2 in female and male athletes. In young people who did not practice weightlifting, BMD in the lumbar spine (0.9 g/cm2 in both groups) and TMDV (1.05 g/cm2 in women and 1.11 g/cm2 in men) were significantly lower (p <0.05). The activity in bone formation and CK in male athletes was twice as high compared to the other groups. The blood urea concentration in athletes (32.7- 38.0 mg/dL) was significantly higher (p <0.05) compared to the control groups (19.3-18.8 mg/dL).

Conclusion:
The practice of weightlifting benefits bone mass gain in the lumbar spine. These findings suggest that exercises in which high weight loads are supported promote bone turnover and mineralization to prevent bone weakening.
Water Polo Performance Classification Based on the Functional Test for Agility Performance: A Long-Term Training Tool
Authors: Tucher Guilherme , Telles Silvio de Cássio Costa , Cabral Ricardo Gomes , Garrido Nuno Domingos , de Souza Castro Flávio Antônio 
Published: December 2021

Background:
Water polo is an open-skilled team sport in which agility is important.

Objective:
This study aimed to propose a water polo player classification based on the Functional Test for Agility Performance.

Methods:
A total of 78 male water polo players of different competition levels (7.7% regional, 52.5% national and 39.7% international), years of training (6.7 ± 4.5; 2-25 years), weekly training frequency (6.1 ± 2.1; 2-12) and age (18.1 ± 4.3; 12-36) were evaluated in the Functional Test for Agility Performance. Hierarchical Cluster Analysis was used in five levels to classify water polo player performance.

Results:
The players were classified based on the Functional Test for Agility Performance as excellent (≤ 3.22 s), very good (3.23-4.48 s); good (4.49-4.76 s); under development (4.77-5.11 s) and learning (≥ 5.12 s). Age, years of training, and weekly training frequency showed a decreasing trend from Gr1 to Gr4. Athletes at the international level ranked primarily in the best performing groups (Gr1 and Gr2, n = 30), the ones at the national level in the intermediate groups (Gr2, Gr3 and Gr4; n = 41), with a higher concentration in Gr2, and those at regional level mainly in Gr4 (n = 4).

Conclusion:
This classification proposal is expected to be useful as a tool to evaluate the training of athletes of different competition levels as well as to follow up on water polo athletes in long-term training.
Synthesis and characterization of permanent magnetic oxide system Ba1-x-yLaxCeyFe12O19 system doped with La-Ce metal using wet mechanical milling method
Authors: Adnyana I Gusti Agung Putra , Sukarasa I Ketut , Suarbawa Komang Ngurah 
Published: December 2021

The development of permanent magnet-based rare earth metals becomes a serious problem if the raw materials are difficult to find. The solution chosen is to utilize an oxide-based permanent magnet with little substitution of rare earth metals. In this study presented a permanent magnetic synthesis of barium hexaferrite-based oxides that were doped with La and Ce atoms. The synthesis of this material uses the wet mechanical milling technique to obtain the single phase permanent magnet system Ba1-x-yLaxCeyFe12O19 (x = 0, 0.02, 0.04 and y = 0. 0.05, 0.1). The precursor is weighed according to stoichiometric composition and is milled for 5 hours then compressed at a pressure of 7000 Psi. Sintering temperature for the formation of the barium hexaferrite phase at 1200oC for 2 hours. All samples after sintering were characterized using XRD and EDS. A single phase is obtained on all sample compositions with a hexagonal P63/mmc structure and is supported by elemental analysis data that each substituted sample contains elements La and Ce. Lattice parameters a, b, and c appear to decrease with increasing concentrations of La and Ce doping ions with a ratio of c/a in the range of 3.93-3.94.
IL CULTO DEI SERVI DI DIO VESCOVI MARTIRI ROMENI: FRA DIRITTO CANONICO E LITURGIA
Authors: A. BLEIZIFFER William 
Published: December 2021

The Cult of God’s Servants Romanian Martyr Bishops: between Canon Law and Liturgy. On the last day of his apostolic trip to Romania (May 31 - June 2, 2019), the Holy Father Pope Francis in the exercise of his canonical powers beatified seven Romanian Greek Catholic bishops who died in odium fidei in communist prisons. By proclaiming the formula for recognizing the martyrdom of these bishops, they are officially recognized as martyrs of the Church of Christ, and as such, according to the canonical discipline in force, they can enjoy the celebration of a public cult of worship. Their feast finds a stable place in the liturgical calendar of the Greek Catholic Church, June 2, and public worship regulated by both common law and the particular law of the Church becomes a liturgical constant that manifests the particular character of these servants of God. Starting from this canonical and liturgical premise, the present study tries to highlight some significant elements regarding the liturgical cult of these martyrs. Thus, a series of disciplinary realities are taken into account, which starting from the historical elements of the cult of saints, then highlights some particular aspects that the current procedure of declaring the martyrdom of God’s servants requires to regulate their public worship.
Cultul servilor lui Dumnezeu episcopi martiri români: între drept canonic și liturgie. În ultima zi a călătoriei sale apostolice în România (31 mai - 2 iunie 2019), Sfântul Părinte Papa Francisc în exercitarea propriilor competențe canonice a beatificat șapte episcopi greco-catolici români morți in odium fidei în închisorile comuniste. Prin proclamarea formulei de recunoaștere a martiriului acestor episcopi, ei sunt recunoscuți oficial ca și martiri ai Bisericii lui Cristos, și ca atare, conform disciplinei canonice în vigoare se pot bucura de celebrarea unui cult public de venerare. Sărbătoarea lor găsește un loc stabil în calendarul liturgic al Bisericii Greco-Catolice, 2 iunie, iar cultul public reglementat deopotrivă de dreptul comun și dreptul particular al Bisericii devine o constantă liturgică ce manifestă caracterul particular al acestor servi ai lui Dumnezeu. Pornind de la această premisă canonică și liturgică, studiul de față încercă să evidențieze câteva elemente semnificative cu privire la cultul liturgic al acestor martiri. Astfel sunt luate în considerare o serie de realități disciplinare care plecând de la elementele istorice ale cultului sfinților, evidențiază mai apoi unele aspecte particulare pe care procedura actuală de declararea a martiriului servilor lui Dumnezeu le impun pentru a reglemente cultul public al acestora.
Cuvinte-cheie: cult divin, venerare, Servi ai lui Dumnezeu, martiri, liturgie, texte liturgice, fericit, cauza de beatificare, persecuție.
Maqamat Sufi dan Tafsir Alquran
Authors: Wathani Syamsul , Muluk Tajul 
Published: December 2021

”The history of Qur’anic Exegesis shows that there is a pattern of interpretation of the Qur’an that originates not only from reasoning (ta'aqquli), but also from spiritual emanations (at'ta'ammul ad-diniyyah). The importance of understanding the exegetical patterns/models driven by the Sufis, in order to become a better alternative to the patterns of understanding/interpreting the Qur’an. This article will conduct an analysis with a focus on: Sufi interpretation; scientific analysis and religious appreciation, discourse of meaning in Sufi interpretation, and patterns/models of al-Qusyairi's Sufistism interpretation. The research framework used is Abdullah Saeed's hierarchy of values to read the hierarchy of meaning of the Sufi al-Qusyairi interpretation. The findings of this research include: Sufi interpretation is a tafir based on knowledge (knowledge) and the depth of Islamic charity (experience). Al-Qusyair Sufi interpretation is elaborates between knowledge and Islamic spiritual experience. In the discourse of meaning, Sufi interpretation is based on the condition of the Sufi soul at different states (ahwal) and spiritual levels (maqamat). However, mystical perception of the Qur’an must come to terms with its birth meaning. The Sufistic interpretation of al-Qusyairi can combine the meaning of isyariyyah with the meaning of lahiriah verse. Al-Qusyairi understands that the contents of the Koran have three levels of meaning according to the level of maqa>m in the concept of tasawwuf, namely: 'irfani, burhani and bayani.
Pandemic heroes or victims? Healthcare professionals’ well-being during Covid-19 pandemic
Authors: Soroka Ewelina 
Published: December 2021

AbstractIntroduction and aim:The SARS-CoV-2 pandemic had a significant impact on the mental condition of the society, increasing anxiety and fear for the future. High levels of anxiety, stress and depression have been observed in the general population. Nurses and doctors, who are in direct contact with patients and their body fluids, are at the highest risk of infection. The aim of this study was to look at the psychiatric health aspects of health care professionals in general during the pandemic.State of knowledge:Work overload and stress-related symptoms make healthcare workers particularly vulnerable to mental distress, increasing the risk of developing mental disorders. Among them, women, students and nurses were most affected. A German study found that nurses working with COVID-19 patients in particular are mentally affected by the consequences of the pandemic. This may be due to the higher workload and the longer time spent in direct contact with COVID-19 patients compared to doctors. The available literature confirmed the construct of coronaphobia in health care workers. The issue of insufficient personalization of protective equipment and the associated feelings of fear and stigma as well as the need for psychological help are addressed and psychiatric services for healthcare professionals.Material and methods:At the beginning of this year, 30 people from the clinical hospital in Lublin were surveyed using a questionnaire containing several questions concerning, among others, comfort of work in the current epidemiological situation, The Patient Health Questionnaire-9, The Generalized Anxiety Disorder-7 and Mini-COPE.Conclusions:The work shows the mental health problems faced by health service representatives on a daily basis in connection with the pandemic that has been going on for many months. The features of depression-anxiety disorders affect the medical staff. The attitude of solidarity and cooperation of all members of society during the pandemic is important.