bluuebunny/crossref_metadata_2025_split huggingface dataset:
Simulation modeling to assess performance of integrated healthcare systems: Literature review to characterize the field and visual aid to guide model selection
Authors: Larrain Nicolas , Groene Oliver 
Published: July 2021

Background
The guiding principle of many health care reforms is to overcome fragmentation of service delivery and work towards integrated healthcare systems. Even though the value of integration is well recognized, capturing its drivers and its impact as part of health system performance assessment is challenging. The main reason is that current assessment tools only insufficiently capture the complexity of integrated systems, resulting in poor impact estimations of the actions taken towards the ‘Triple Aim’. We describe the unique nature of simulation modeling to consider key health reform aspects: system complexity, optimization of actions, and long-term assessments.

Research question
How can the use and uptake of simulation models be characterized in the field of performance assessment of integrated healthcare systems?

Methods
A systematic search was conducted between 2000 and 2018, in 5 academic databases (ACM D. Library, CINAHL, IEEE Xplore, PubMed, Web of Science) complemented with grey literature from Google Scholar. Studies using simulation models with system thinking to assess system performance in topics relevant to integrated healthcare were selected for revision.

Results
After screening 2274 articles, 30 were selected for analysis. Five modeling techniques were characterized, across four application areas in healthcare. Complexity was defined in nine aspects, embedded distinctively in each modeling technique. ‘What if?’ & ‘How to?’ scenarios were identified as methods for system optimization. The mean time frame for performance assessments was 18 years.

Conclusions
Simulation models can evaluate system performance emphasizing the complex relations between components, understanding the system’s adaptability to change in short or long-term assessments. These advantages position them as a useful tool for complementing performance assessment of integrated healthcare systems in their pursuit of the ‘Triple Aim’. Besides literacy in modeling techniques, accurate model selection is facilitated after identification and prioritization of the complexities that rule system performance. For this purpose, a tool for selecting the most appropriate simulation modeling techniques was developed.
Efficacy of “Essential Iodine Drops” against Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2)
Authors: Köntös Zoltán 
Published: July 2021

Background
Aerosolization of respiratory droplets is considered the main route of coronavirus disease 2019 (COVID-19). Therefore, reducing the viral load of Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2) shed via respiratory droplets is potentially an ideal strategy to prevent the spread of the pandemic. The in vitro virucidal activity of intranasal Povidone-Iodine (PVP-I) has been demonstrated recently to reduce SARS-CoV-2 viral titres. This study evaluated the virucidal activity of the aqueous solution of Iodine-V (a clathrate complex formed by elemental iodine and fulvic acid) as in Essential Iodine Drops (EID) with 200 μg elemental iodine/ml content against SARS-CoV-2 to ascertain whether it is a better alternative to PVP-I.

Methods
SARS-CoV-2 (USAWA1/2020 strain) virus stock was prepared by infecting Vero 76 cells (ATCC CRL-1587) until cytopathic effect (CPE). The virucidal activity of EID against SARS-CoV-2 was tested in three dilutions (1:1; 2:1 and 3:1) in triplicates by incubating at room temperature (22 ± 2°C) for either 60 or 90 seconds. The surviving viruses from each sample were quantified by a standard end-point dilution assay.

Results
EID (200 μg iodine/ml) after exposure for 60 and 90 seconds was compared to controls. In both cases, the viral titre was reduced by 99% (LRV 2.0). The 1:1 dilution of EID with virus reduced SARS-CoV-2 virus from 31,623 cell culture infectious dose 50% (CCID50) to 316 CCID50 within 90 seconds.

Conclusion
Substantial reductions in LRV by Iodine-V in EID confirmed the activity of EID against SARS-CoV-2 in vitro, demonstrating that Iodine-V in EID is effective at inactivating the virus in vitro and therefore suggesting its potential application intranasally to reduce SARS-CoV-2 transmission from known or suspected COVID-19 patients.
The experiences of family caregivers of people with severe mental illness in the Middle East: A systematic review and meta-synthesis of qualitative data
Authors: Alyafei Aisha Hamed , Alqunaibet Taghrid , Mansour Hassan , Ali Afia , Billings Jo 
Published: July 2021

Background
There is a wealth of literature exploring the experiences of family caregivers of people with severe mental illness (SMI) in western countries, however, this topic has been neglected in the Middle East, despite families being the main source of caregiving in this context. The purpose of this review was to conduct a systematic review and qualitative meta-synthesis to explore the experiences of family caregivers living in countries in the Middle East caring for a relative with severe mental illness.

Methods
A systematic review and meta-synthesis were conducted, to comprehensively gain a thorough and detailed overview of what is known about family caregivers’ experiences from published qualitative research in the Middle East geographical area from inception to May 2021. The review protocol was pre-registered with PROSPERO (Ref: CRD42020165519).

Results
The review identified twelve qualitative studies that explored caregivers’ experiences of caring for relatives with SMI in Middle East countries. Family caregivers’ experiences were captured under seven overarching themes. The participants across all studies reported negative consequences of providing care, increased burden and emotional distress. Many experienced issues with family/marital relationships and stigmatizing attitudes and behaviours from their communities. Caregivers expressed the need for increased support which was perceived to have a critical role in improving family caregivers’ experiences.

Conclusions
The meta-synthesis revealed many challenges and issues that affect caregivers of people with SMI in the Middle East. Family caregivers experienced distress and burden, and reported significant impact on their psychological well-being. Their experiences highlight the urgent need to provide more support for family caregivers in Middle East countries.
Perceived ability to comply with national COVID-19 mitigation strategies and their impact on household finances, food security, and mental well-being of medical and pharmacy students in Liberia
Authors: Davis Elvis J. , Amorim Gustavo , Dahn Bernice , Moon Troy D. 
Published: July 2021

Introduction
From the outset of the COVID-19 pandemic, guidance from WHO has promoted social distancing, wearing face masks, frequent hand washing, and staying-at-home as measures to prevent the spread of COVID-19. For many across Africa, compliance can be difficult. The aim of this study was to 1) understand the impact of student’s household’s ability to comply with COVID-19 mitigation strategies, 2) identify predictors of mitigation strategy compliance, and 3) describe the impact of COVID-19 on household economics, food-security, and mental well-being.

Materials and methods
We conducted an email-based survey among current medical and pharmacy students of the University of Liberia College of Health Sciences between July and October 2020. The questionnaire was designed to explore their household’s ability to comply with current mitigation strategies, as well as the pandemic´s impact on the student’s household’s finances and food security. Descriptive statistics were used to delineate demographic characteristics. Logistic regression was used to model factors associated with ability to comply with COVID-19 mitigation strategies, as well as participant’s food security.

Results
113 persons responded to the questionnaire. Seventy-six (67∙3%) reported income losses as a result of the pandemic, with 93 (82∙3%) reporting being “somewhat” or “very worried” about their households’ finances. Seventy-seven (68∙1%) participants reported food stocks that were sufficient for one-week or less. Forty (35%) participants reported eating less preferred foods or skipping meals in the past week. Overall, 20 participants (19∙4%) had a positive depression screen.

Conclusions
Study participants showed mixed results in being able to adhere to national COVID-19 mitigation strategies, with household level stressors experienced around finances and food security. Until Liberia has access to vaccinations for most of its citizens, COVID-19 response measures need to provide social protections that address basic needs (shelter, clothing and food), and which specifically targets food insecurity. Preventative interventions for mental health problems must be incorporated into Liberia’s response to the pandemic.
Association between intraoperative fluid balance, vasopressors and graft complications in liver transplantation: A cohort study
Authors: Larivière Jordan , Giard Jeanne-Marie , Zuo Rui Min , Massicotte Luc , Chassé Michaël , Carrier François Martin 
Published: July 2021

IntroductionBiliary complications following liver transplantation are common. The effect of intraoperative fluid balance and vasopressors on these complications is unknown.Materials and methodsWe conducted a cohort study between July 2008 and December 2017. Our exposure variables were the total intraoperative fluid balance and the use of vasopressors on ICU admission. Our primary outcome was any biliary complication (anastomotic and non-anastomotic strictures) up to one year after transplantation. Our secondary outcomes were vascular complications, primary graft non-function and survival.ResultsWe included 562 consecutive liver transplantations. 192 (34%) transplants had a biliary complication, 167 (30%) had an anastomotic stricture and 56 had a non-anastomotic stricture (10%). We did not observe any effect of intraoperative fluid balance or vasopressor on biliary complications (HR = 0.97; 95% CI, 0.93 to 1.02). A higher intraoperative fluid balance was associated with an increased risk of primary graft non-function (non-linear) and a lower survival (HR = 1.40, 95% CI, 1.14 to 1.71) in multivariable analyses.ConclusionIntraoperative fluid balance and vasopressors upon ICU admission were not associated with biliary complications after liver transplantation but may be associated with other adverse events. Intraoperative hemodynamic management must be prospectively studied to further assess their impact on liver recipients’ outcomes.
La integración de las TIC en la formación bilingüe: perspectivas en la formación del profesorado
Authors: García Laborda Jesús 
Published: July 2021

Son numerosos los estudios que atestiguan que las experiencias como discente o incluso las vivencias propias son, de alguna manera, el prima que mediatiza la actuación en el aula del docente. Por eso, el valor de las actitudes del profesorado en formación condiciona su propia carrera docente en los primeros años. En una época en la que el término “nativo digital” está siento sustituido por “usuario digital” bien cabe la pregunta sobre cuál es la presencia en el aula bilingüe de las nuevas tecnología. En este trabajo se presenta un estudio realizado en la universidad de Alcalá a través de un cuestionario sobre las actitudes de uso de tecnología digital de futuros profesores para colegios bilingües.
Las corrientes interpretativas de la comunicación educativa ante la sociedad del conocimiento. una perspectiva sociocrítica
Authors: De La Herrán Gascón Agustín , Coro Montanet Gleyvis 
Published: July 2021

El concepto de comunicación educativa ha sacudido la época contemporánea y ha sido condicionado por la explosión tecnológica. El presente artículo se propone contrastar críticamente las líneas de pensamiento generadas en torno al problema de los medios de comunicación de masas y las nuevas tecnologías de la información, cuya intelección parece determinada por la renovación tecnológica. Mediante una revisión de las fundamentales corrientes tradicionalistas y de la corriente representacional y analizando las aportaciones semióticas, estéticas y gramscianas, el artículo cuestiona mediante una metodología hermenéutica la tendencia a efectuar interpretaciones antagónicas, excesivamente instrumentales y reduccionistas sobre el problema de estudio. Paralelamente se considera que la corriente informacional, heredera de un modelo de educación bancaria, ostenta la primacía en las prácticas educativas al uso. En tal contexto y por su capacidad integradora, se asume la metodología de la educación popular de Paulo Freire como la más adecuada ‘teoría de la comunicación educativa’, dirigida a la generación de conocimiento para el cambio social.
La robótica como un recurso para facilitar el aprendizaje y desarrollo de competencias generales
Authors: Bravo Sánchez Flor Ángela , Forero Guzmán Alejandro 
Published: July 2021

La creciente importancia que tiene la tecnología en el mundo hoy en día y su continuo desarrollo, hace que la tecnología, en sí misma, se convierte en parte integral del proceso de formación en la niñez y la juventud. Por esta razón es importante desarrollar propuestas en las que se ofrezca a niños y jóvenes la posibilidad de entrar en contacto con las nuevas tecnologías; esto es posible a través del manejo de herramientas de software y hardware, como prototipos robóticos y programas especializados con fines pedagógicos. Este artículo muestra la importancia que tiene el uso de la robótica como una herramienta de aprendizaje y presenta las etapas típicas que se deben afrontar al implementar proyectos de robótica educativa en el aula de clase. También se da a conocer un proyecto de robótica educativa denominado “Mundo Robótica” el cual busca involucrar la robótica en el aula de clase por medio de actividades prácticas y recursos de aprendizaje articulados desde una plataforma virtual.
Percepciones de los futuros docentes sobre la cultura organizacional de los centros de prácticas externas de Educación Secundaria
Authors: Morales Rodríguez Francisco Manuel , Narváez Peláez Manuel Alejandro , Morales Rodríguez Ana María 
Published: July 2021

El objetivo general del presente trabajo es aportar los resultados iniciales de pasar un cuestionario sobre cultura organizacional en los Centros de Educación Secundaria a 57 futuros docentes estudiantes del Máster Universitario en Profesorado de Educación Secundaria Obligatoria y Bachillerato, Formación Profesional y Enseñanza de Idiomas por la Universidad de Málaga correspondientes a la especialidad de Tecnología, Informática y Procesos Industriales. Los resultados demuestran que el profesorado principiante considera que el profesorado debe realizar su docencia teniendo en cuenta la diversidad del alumnado en su aula, revisar sus técnicas y estrategias didácticas en proceso de formación y actualización permanente. Se encuentran además diferencias en la percepción de la cultura organizacional de los Centros de Educación Secundaria en función del género en lo que respecta a variables relacionadas con las funciones de la Institución, el gobierno de los centros, la financiación, la metodología, el alumnado, la evaluación y las relaciones con el entorno. Los datos obtenidos son útiles para la mejora de las acciones de formación necesarias, evaluación de posibles sesgos al respecto y su adaptación a los retos y desafíos que tiene planteada la Educación Secundaria.
E-infocenter, Una herramienta visual para la gestión de proyectos en robótica educativa usando tecnologías web
Authors: Pittí Patiño Kathia , Curto Diego Belén , Moreno Rodilla Vidal 
Published: July 2021

Las tecnologías como Internet y la robótica educativa, caracterizadas por ser relativamente nuevas y motivadoras, son el escenario ideal para la aplicación de los métodos activos de enseñanza, tal es el caso del aprendizaje basado en proyectos. La realización de proyectos con robots apoyados por el entorno colaborativo de la Web 2.0, puede ayudar al alumnado a desarrollar una serie de competencias transferibles al ámbito laboral. En este artículo se describe el proceso de selección, diseño e implementación de una herramienta visual en línea denominada E-infocenter para la gestión de proyectos. Esta herramienta ha sido utilizada por primera vez durante seis semanas en el Taller Vehicles NXT con robots LEGO, dirigido a niños de edades comprendidas entre 8 y 15 años. Los beneficios percibidos por los participantes han sido a nivel de gestión, emocional y de colaboración.
Assessment of oral health- related quality of life in patients with lichen planus during the course of treatment, using “Chronic Oral Mucosal Disease Questionnaire”
Authors: Baharvand Maryam , Jaberi Maryam , Hajighasem Parisa , Ahmadieh Azadeh 
Published: July 2021

Objective: The aim of this study was to assess the oral health related quality of life in patients with oral lichen planus, using a Chronic Oral Mucosal Diseases Questionnaire (COMDQ) during a course of standard medical treatment. Material and Methods: In this experimental study, fifteen patients with oral lichen planus were entered the study and the COMDQ (a self reported questionnaire assessing different aspects of quality of life in individuals with chronic oral mucosal diseases), ), was used to assess the level of “Pain and functional limitation”, “Medication and treatment”, “Social emotional” and “Patient support” during the course of standard treatment. A data collection form including demographic information, type and location of the lesions, patients’ symptoms and level of healing process was completed. Patients were evaluated weekly during four weeks of treatment and COMDQ scores were documented. Data were analyzed, using ANOVA and Friedman statistical tests. Results: The mean score of the COMDQ questionnaire in lichen planus patients who completed the course of treatment, showed significant improvement (P < 0.001) after each week of therapy. Oral symptoms and the healing process of oral lesions showed improvement without any statistically significant changes among different weeks of therapy. “Pain and functional limitation”, “Medication and treatment” and “Patient Support” improved significantly during the treatment period (P<001); however, the “Social and emotional” aspect did not show significant changes over the course of medical management. Conclusion: Oral health-related quality of life in patients with oral lichen planus improved significantly during the course of medical treatment.

Keywords
Oral Lichen Planus; COMDQ; Quality of Life; Oral Health.
Split-Block Graft Versus Cortico-cancellous Block Graft for Horizontal Ridge Augmentation: Cone Beam Computed Tomography and Histomorphometric Study
Authors: Botros Mina , Kamal Adbel Gaber Hala , Abbas Effat , El-Mofty Mohamed , Bissar Mohamed 
Published: July 2021

Objective: The aim of this study was to compare the horizontal dimensional changes of split-bone block and cortico-cancellous block graft in horizontal ridge augmentation using Cone Beam Computed Tomography (CBCT). The quality of the regenerated bone in both groups was compared histologically and histomorphometrically. Material and methods: Twenty patients were randomly divided in two equal groups (n= 10): Split-bone block group which was harvested from the external oblique ridge or cortico-cancellous block graft group which was harvested from the mandibular symphysis. Pre-augmentation crestal ridge width was measured using bone caliper. CBCT scans were taken on the 2nd week and 4th month post-operatively to measure crestal and total horizontal ridge dimensions. A biopsy was collected from the regenerated ridge immediately before implant insertion on the 4th month post-operatively. Results: Pre-augmentation crestal bone widths of both groups were comparable (P= 0.870). On the 2nd week and 4th month post-operatively, split-bone block showed a significantly wider crestal (P= 0.028 and P= 0.001 respectively) and total horizontal ridge dimension (P= 0.025 and P= 0.002 respectively), and on the 4th month post-operatively, it showed significantly lesser resorption at crest (P= 0.040) and in total horizontal ridge dimension (P= 0.017) than cortico-cancellous block. Histologically, the regenerated bone quality was similar in both groups. Histomorphometric analysis showed a non-significant difference in percentage of mature (P= 0.365) and immature collagen (P= 0.531) between both groups. Conclusion: Split-bone block maintained a significantly wider ridge and experienced less resorption after 4 months than the cortico-cancellous block graft, with no difference in regenerated bone quality between both groups.

Keywords
Dental implants; CBCT; Cortico-cancellous block graft; Histomorphometric analysis; Split-bone block technique.
One-year clinical evaluation of IPS Empress CAD versus polished Celtra Duo ceramic Laminate veneers (randomized controlled clinical trial)
Authors: Elbanna Hayat , Zamzam Mohammed Labib , El-Guindy Jylan Fouad , Idris Ahmed Soliman 
Published: July 2021

Objective: To evaluate fracture resistance and survival rate of IPS Empress CAD versus Polished Celtra Duo ceramic laminate veneers. Material and Methods: Thirty-six ceramic laminate veneers were fabricated for maxillary anterior teeth. The patients were divided into two groups according to the material Group 1(control group) fabricated from IPS Empress CAD laminate veneers and group 2(intervention group) fabricated from Polished Celtra Duo laminate veneers. Standardized the same preparation with butt joint design and chamfer finish line located supra gingival were performed for all the teeth. The fabrication of the veneers was performed using Cad\Cam (Ceramill motion) machine, with software (Exocad). The veneers surfaces were treated and silanated according to the manufacture instruction of each ceramic and enamel surfaces were etched where total etch adhesive protocol was obeyed using BISCO. Follow up sessions were done every two months up to one year for each patient using dental probe and operator vision to evaluate the fracture, survival rate, marginal adaptation, sensitivity and caries. according to USPHS criteria (United States Public Health Service). This was performed by an experienced, blinded investigator. Results: Fracture resistance, marginal adaptation, retention, caries and sensitivity were evaluated according to the criteria of USPHS and we found there is no significant difference as both groups scaled zero score. Conclusion: Both IPS Empress Cad and Polished Celtra Duo laminate veneers revealed successful clinical performance in terms of fracture resistance, marginal adaptation, retention, and sensitivity after one year follow up period.

Keywords
Ceramic laminate veneers; IPS Empress CAD; Celtra DUO; Clinical performance.
On split quaternion equivalents for Quaternaccis, shortly Split Quaternaccis
Authors: Bajorska-Harapińska Beata , Ludew Jakub Jan , Smoleń-Duda Barbara , Wituła Roman 
Published: July 2021

Abstract
In this paper, we introduce generalizations of Quaternacci sequences (Quaternaccis), called Split Quaternacci sequences, which arose on a base of split quaternion algebras. Explicit and recurrent formulae for Split Quaternacci sequences are given, as well as generating functions. Also, matrices related to Split Quaternaccis sequences are investigated. Moreover, new identities connecting Horadam sequences with other known sequences are generated. Analogous identities for Horadam quaternions and split Horadam quaternions are proved.