bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thalamic dysconnectivity in the psychosis risk syndrome and early illness schizophrenia
Authors: Fryer Susanna L. , Ferri Jamie M. , Roach Brian J. , Loewy Rachel L. , Stuart Barbara K. , Anticevic Alan , Ford Judith M. , Mathalon Daniel H. 
Published: March 2021

AbstractBackgroundSchizophrenia (SZ) is associated with thalamic dysconnectivity. Compared to healthy controls (HCs), individuals with SZ have hyperconnectivity with sensory regions, and hypoconnectivity with cerebellar, thalamic, and prefrontal regions. Despite replication of this pattern in chronically ill individuals, less is known about when these abnormalities emerge in the illness course and if they are present prior to illness onset.MethodsResting-state functional magnetic resonance imaging data were collected from psychosis risk syndrome (PRS) youth (n = 45), early illness SZ (ESZ) (n = 74) patients, and HCs (n = 85). Age-adjusted functional connectivity, seeded from the thalamus, was compared among the groups.ResultsSignificant effects of group were observed in left and right middle temporal regions, left and right superior temporal regions, left cerebellum, and bilateral thalamus. Compared to HCs, ESZ demonstrated hyperconnectivity to all temporal lobe regions and reduced connectivity with cerebellar, anterior cingulate, and thalamic regions. Compared to HCs, PRS demonstrated hyperconnectivity with the left and right middle temporal regions, and hypoconnectivity with the cerebellar and other thalamic regions. Compared to PRS participants, ESZ participants were hyperconnected to temporal regions, but did not differ from PRS in hypoconnectivity with cerebellar and thalamic regions. Thalamic dysconnectivity was unrelated to positive symptom severity in ESZ or PRS groups.ConclusionsPRS individuals demonstrated an intermediate level of thalamic dysconnectivity, whereas ESZ showed a pattern consistent with prior observations in chronic samples. These cross-sectional findings suggest that thalamic dysconnectivity may occur prior to illness onset and become more pronounced in early illness stages.
Mobilization Campaigns and Rural Development
Authors: Looney Kristen E. 
Published: March 2021

ABSTRACTMost accounts of East Asian economic growth have focused on the role of developmental states in successful industrialization. This article expands and challenges that framework by showing that rural policy was different from industrial policy. A key finding is that for more than a century, East Asian states have relied on mass mobilization campaigns rather than on technocratic planning and market-conforming institutions to achieve rural development. Based on case studies of Japan, South Korea, Taiwan, and China, the author argues that three main factors explain the rise of campaign states: revolutionary traditions, rural populism, and policy learning. A brief assessment of outcomes illustrates the payoffs and costs of campaigns and the practical considerations that drive them. The author’s analysis offers a new perspective on the East Asian model and disputes the widely held view that campaigns are tragic exercises in social control, demonstrating instead that they were central to the region’s rural transformation.
Historicizing the comparative survey of freedom: tracing the social trajectory of an influential indicator
Authors: Zerndt Emily 
Published: March 2021

ArgumentThe Comparative Survey of Freedom, first published by Freedom House in 1973, is now the most widely used indicator of democracy by both academics and the U.S. government alike. However, literature examining the Survey’s origins is virtually nonexistent. In this article, I use archival records to challenge Freedom House’s retrospective account of the indicator’s creation. Rather than the outcome of a scientific methodology by multiple social scientists, the Survey was produced by a single political scientist, Raymond Gastil, according to his own hunches and impressions. How, then, did this indicator rise to such prominence? I argue that the Survey’s notoriety can be attributed to its early promotion in both political science and American foreign policy decision-making, as well as the fact that it fit the dominant scientific and political paradigms of the time.
A Monte Carlo evaluation of growth mixture modeling
Authors: Shader Tiffany M. , Beauchaine Theodore P. 
Published: March 2021

AbstractGrowth mixture modeling (GMM) and its variants, which group individuals based on similar longitudinal growth trajectories, are quite popular in developmental and clinical science. However, research addressing the validity of GMM-identified latent subgroupings is limited. This Monte Carlo simulation tests the efficiency of GMM in identifying known subgroups (k = 1–4) across various combinations of distributional characteristics, including skew, kurtosis, sample size, intercept effect size, patterns of growth (none, linear, quadratic, exponential), and proportions of observations within each group. In total, 1,955 combinations of distributional parameters were examined, each with 1,000 replications (1,955,000 simulations). Using standard fit indices, GMM often identified the wrong number of groups. When one group was simulated with varying skew and kurtosis, GMM often identified multiple groups. When two groups were simulated, GMM performed well only when one group had steep growth (whether linear, quadratic, or exponential). When three to four groups were simulated, GMM was effective primarily when intercept effect sizes and sample sizes were large, an uncommon state of affairs in real-world applications. When conditions were less ideal, GMM often underestimated the correct number of groups when the true number was between two and four. Results suggest caution in interpreting GMM results, which sometimes get reified in the literature.
Liver fibrosis in patients with tetralogy of Fallot, an unrecognised complication?
Authors: Ravndal Maren E. H. , Borgwardt Lise , Juul Klaus , Nielsen Jon , Borgwardt Lotte , Henriksen Birthe M. , Willemoe Gro L. , Jensen Annette S. , Christensen Vibeke B. , Kjær Mette S. 
Published: March 2021

AbstractObjectives:Improved survival has led to a growing population of adults with congenital heart disease (CHD), followed by numerous reports of late complications. Liver disease is a known complication in some patients, with most studies focusing on Fontan associated liver disease. Whether liver disease also exists in other patients with CHD is not fully investigated. Elevated central venous pressure is considered pivotal in the development of liver disease in Fontan associated liver disease, and other patients with alterations in central venous pressure may also be at risk for developing liver fibrosis. We wanted to see if liver fibrosis is present in patients with tetralogy of Fallot. Many patients with tetralogy of Fallot have severe pulmonary regurgitation, which can lead to elevated central venous pressure. Patients with tetralogy of Fallot may be at risk of developing liver fibrosis.Materials and methods:Ten patients (24–56 years) with tetralogy of Fallot and pulmonary regurgitation were investigated for liver fibrosis. All patients were examined with magnetic resonance elastography of liver, hepatobiliary iminodiacetic acid scan, indocyanine green elimination by pulse spectrophotometry, elastography via FibroScan, abdominal ultrasound including liver elastography, and blood samples including liver markers.Results:Three out of ten patients had findings indicating possible liver fibrosis. Two of these had a liver biopsy performed, which revealed fibrosis stage 1 and 2, respectively. The same three patients had an estimated elevated central venous pressure in previous echocardiograms.Conclusions:Mild liver fibrosis was present in selected patients with tetralogy of Fallot and may be related to elevated central venous pressure.
Magnesium intake, insulin resistance and markers of endothelial function among women
Authors: Bavani Narges Ghorbani , Saneei Parvane , Hassanzadeh Keshteli Ammar , Yazdannik Ahmadreza , Falahi Ebrahim , Sadeghi Omid , Esmaillzadeh Ahmad 
Published: March 2021

AbstractObjective:We investigated the association of dietary Mg intake with insulin resistance and markers of endothelial function among Iranian women.Design:A cross-sectional study.Setting:Usual dietary intakes were assessed using a validated FFQ. Dietary Mg intake was calculated by summing up the amount of Mg in all foods. A fasting blood sample was taken to measure serum concentrations of glycemic indices (fasting plasma glucose and insulin) and endothelial function markers (E-selectin, soluble intercellular adhesion molecule-1 (sICAM-1) and soluble vascular cell adhesion molecule-1). Insulin resistance and sensitivity were estimated using the Homeostasis Model Assessment-Insulin Resistance (HOMA-IR), Homeostasis Model Assessment β-cell function (HOMA-β) and quantitative insulin sensitivity check index (QUICKI).Participants:Iranian female nurses (n 345) selected by a multistage cluster random sampling method.Results:The Mg intake across energy-adjusted quartiles was 205 (se 7), 221·4 (se 8), 254·3 (se 7) and 355·2 (se 9) mg/d, respectively. After adjustments for potential confounders, QUICKI level was significantly different across quartiles of Mg intake (Q1: 0·34 (se 0·02), Q2: 0·36 (se 0·01), Q3: 0·40 (se 0·01), and Q4: 0·39 (se 0·02), P = 0·02); however, this association disappeared after considering markers of endothelial function, indicating that this relation might be mediated through endothelial dysfunction. After controlling for all potential confounders, Mg intake was inversely, but not significantly, associated with serum concentrations of sICAM (Q1: 239 (se 17), Q2: 214 (se 12), Q3: 196 (se 12), and Q4: 195 (se 17), P = 0·29). There was no other significant association between dietary Mg intake and other indicators of glucose homoeostasis or endothelial markers.Conclusions:Higher dietary Mg intake was associated with better insulin sensitivity in Iranian females. This linkage was mediated through reduced endothelial dysfunction.
Happiness at the end of life: A qualitative study
Authors: Beng Tan Seng , Ghee Wong Ka , Hui Ng Yun , Yin Ooi Chieh , Kelvin Khoo Wei Shen , Yiling See Toh , Huey Tan Ai , Capelle David Paul , Zainuddin Sheriza Izwa , Chin Loh Ee , Loong Lam Chee 
Published: March 2021

AbstractObjectiveDying is mostly seen as a dreadful event, never a happy experience. Yet, as palliative care physicians, we have seen so many patients who remained happy despite facing death. Hence, we conducted this qualitative study to explore happiness in palliative care patients at the University of Malaya Medical Centre.MethodTwenty terminally ill patients were interviewed with semi-structured questions. The results were thematically analyzed.ResultsEight themes were generated: the meaning of happiness, connections, mindset, pleasure, health, faith, wealth, and work. Our results showed that happiness is possible at the end of life. Happiness can coexist with pain and suffering. Social connections were the most important element of happiness at the end of life. Wealth and work were given the least emphasis. From the descriptions of our patients, we recognized a tendency for the degree of importance to shift from the hedonic happiness to eudaimonic happiness as patients experienced a terminal illness.Significance of resultsTo increase the happiness of palliative care patients, it is crucial to assess the meaning of happiness for each patient and the degree of importance for each happiness domain to allow targeted interventions.
Morphological characterization and genotypic identity of African yam bean (Sphenostylis stenocarpaHochst ex. A. Rich. Harms) germplasm from diverse ecological zones
Authors: Shitta Ndenum Suzzy , Abtew Wosene Gebresalassie , Ndlovu Noel , Oselebe Happiness O. , Edemodu Alex Chukwudi , Abebe Abush Tesfaye 
Published: March 2021

AbstractAfrican yam bean (AYB) is an affordable protein source capable of diversifying the food base in sub-Saharan Africa. However, research efforts made towards the crop's improvement and in expanding production are limited. This study characterized 169 AYB accessions at Jimma, Ethiopia, using 31 phenotypic characters. The analysis of variance revealed highly significant (P< 0.01) differences for days to 50% flowering, days to first flowering, leaf area, number of seeds per pod, pod length, seed thickness, total seed weight, petiole length and significant (P< 0.05) difference for terminal leaf length. Accession TSs62B produced the highest number of seeds per pod (17.65) and recorded the highest 100 seed weight (25.30 g), while 3A was the earliest to flower at an average of 84.50 d. Principal component analysis (PCA) of qualitative traits attributed 77.6% of observed variations to the first five principal components, of which the first two PC axes accounted for 53.6% of total variations. Cluster analysis and PCA biplot distinctly grouped the accessions into two major groups, cluster I had the highest number of accessions (108). The analytical approaches used confirmed considerable diversity across the germplasm with a distance matrix ranging from 0.37 to 0.85. The extent of diversity reflected in the current study provides breeders the baseline information to design breeding strategies, which might help identify materials for release as variety or parental lines for hybridization programmes.
Miniaturized four-port UWB MIMO antennas with triple-band rejection using single EBG structures
Authors: Thakur Ekta , Jaglan Naveen , Dev Gupta Samir 
Published: March 2021

AbstractThis research paper introduces a ultra-wideband (UWB) multiple input multiple output (MIMO)/diversity antenna with three rejected bands using one compact electromagnetic band gap (EBG) structure. The suggested EBG structure rejects three bands at WiMAX, WLAN, and the X-band within the passband of the UWB antenna. To achieve compactness in the conventional EBG structure, two via and square slots are introduced. This structure contributes to better impedance matching by using tapered feedline and slots in the radiating patch. To improve the isolation among all four compact UWB monopoles, decoupling strips are extended from the ground plane. Furthermore, the |S21| is below 17 dB in between the antenna elements and the envelope correlation coefficient is below 0.5, which are tolerable values within the UWB range. Furthermore, different MIMO/diversity characteristics are also discussed. An FR-4 substrate with dimensions of 38 × 45 × 1.6 mm3 is used for the fabrication of the suggested structure.
Thermo‐Mechanical Numerical Modeling of the South American Subduction Zone: A Multi‐Parametric Investigation
Authors: Strak V. , Schellart W. P. 
Published: March 2021

AbstractThe South American subduction zone is enigmatic due to its fast subducting plate consumption, strong oscillation in subducting plate velocity, and deep mantle subduction. A key to help understand these subduction zone characteristics is through studying its dynamics with buoyancy‐driven numerical modeling that uses independent variables to best approximate the dynamics of the real subduction system. We conduct a parametric investigation on the effect of upper mantle rheology, subduction interface yield stress and slab thermal weakening. To constrain those model variables, we attempt to find best‐fits by comparing our model outcomes with the present‐day slab geometry and estimates of Cenozoic velocities in the center of the South American subduction zone. Key ingredients that need to be reproduced are low slab dip angles close to the surface, steeper lower mantle dip angles, strong oscillation of the fast Farallon‐Nazca subducting plate velocity and a progressive decrease in trench retreat rate during long‐term subduction. We include these ingredients to define a model fitting score using 10 criteria. Our best fitting models involve a weak subduction zone interface (yield stress of ∼20 MPa) and significant slab thermal weakening to attain the fast Farallon‐Nazca subducting plate velocity and to better reproduce the subduction partitioning since 48 Ma due to reduced shear stresses resisting downdip slab sinking and reduced slab bending resistance. Furthermore, a non‐Newtonian upper mantle promotes slab folding and realistic oscillation of the subducting plate velocity. Whether and how this slab folding process induces temporal variations in Andean deformation remains an open question.
Rates and Mechanisms of Turbulent Mixing in a Coastal Embayment of the West Antarctic Peninsula
Authors: Scott Ryan M. , Brearley J. Alexander , Naveira Garabato Alberto C. , Venables Hugh J. , Meredith Michael P. 
Published: March 2021

AbstractQuantifying and understanding the processes driving turbulent mixing around Antarctica are key to closing the Southern Ocean's heat budget, an essential component of the global climate system. In 2016, a glider deployed in Ryder Bay, West Antarctic Peninsula, collected hydrographic and microstructure data, obtaining some of the first direct measurements of turbulent kinetic energy dissipation off West Antarctica. Elevated dissipation O(10−8) W kg−1 is found above a topographic ridge separating the 520‐m‐deep bay, where values are O(10−10) W kg−1, from a deep fjord of the continental shelf, suggesting the ridge is important in driving upward mixing of warm Circumpolar Deep Water. The 12 glider transects reveal significant temporal variability in hydrographic and dissipation conditions. Mooring‐based current and nearby meteorological data are used to attribute thermocline shoaling (deepening) to Ekman upwelling (downwelling) at Ryder Bay's southern boundary, driven by ∼3‐day‐long south‐westward (north‐westward) wind events. Anticyclonic winds generated near‐inertial shear in the bay's upper layers, causing elevated bay‐wide shear and dissipation ∼1.7 days later. High dissipation over the ridge appears to be controlled hydraulically, being co‐located (and moving) with steeply sloping isopycnals. These are observed in ∼60% of the transects, with a corresponding mean upward heat flux of ∼2.4 W m−2. The ridge, therefore, provides sustained heat to the base of the thermocline, which can be released into overlying waters during the bay‐wide, thermocline‐focused dissipation events (mean heat flux of ∼1.3 W m−2). This highlights the role of ridges, which are widespread across the West Antarctic Peninsula, in the regional heat budget.
Indispensable Role of the Madden‐Julian Oscillation in the 2019 Extreme Autumn Drought Over Eastern China
Authors: Qi Li , Ji Yue , Zhang Wenjun 
Published: March 2021

AbstractEastern China suffered an extensive drought during autumn (September–October 2019) with precipitation deficits reaching as high as 70% of the climatology, the worst on record since the 1980s. Concurrent with this extreme drought, the tropical Indo–Pacific oceans experienced a central–Pacific (CP) El Niño event with the westernmost location, and the third–ranking positive Indian Ocean Dipole (IOD) event. However, the CP El Niño associated convection anomalies are unexpectedly absent over the western equatorial Pacific, leading to the decoupling of traditional atmospheric–oceanic connections between the tropical Pacific and Indian Oceans. A strong Madden–Julian oscillation (MJO) event stayed in the western Indian Ocean for 32 days during September–October 2019, nearly triple the frequency of climatology. This extraordinary long–lasting MJO activity suppressed the western Pacific convection associated with the CP El Niño and simultaneously enhanced the local IOD–related sea surface temperature anomalies via the atmospheric forcing. The MJO associated convection over the Indian Ocean can excite an anomalous cyclone in the western North Pacific, producing persistently extensive precipitation deficiencies over eastern China. It highlights that the abnormal MJO activity plays a crucial role on the Indo–Pacific atmospheric–oceanic features and the extreme precipitation deficits over eastern China.
Modeling Northern Hemispheric Ice Sheet Dynamics, Sea Level Change, and Solid Earth Deformation Through the Last Glacial Cycle
Authors: Han Holly Kyeore , Gomez Natalya , Pollard David , DeConto Robert 
Published: March 2021

AbstractRetreat or advance of an ice sheet perturbs the Earth's solid surface, rotational vector, and the gravitational field, which in turn feeds back onto the evolution of the ice sheet over a range of timescales. Throughout the last glacial cycle, ice sheets over the Northern Hemisphere have gone through multiple growth and retreat phases, but the dynamics during these phases are not well understood. In this study, we apply a coupled ice sheet‐glacial isostatic adjustment model to simulate the Northern Hemisphere Ice Sheets over the last glacial cycle. We focus on understanding the influence of solid Earth deformation and gravitational field perturbations associated with surface (ice and water) loading changes on the dynamics of terrestrial and marine‐based ice sheets during different phases of the glacial cycle. Our results show that solid Earth deformation enhances glaciation during growth phases and melting during retreat phases in terrestrial regions through ice‐elevation feedback, and gravitational field perturbations have a stabilizing influence on marine‐based ice sheets in regions such as Hudson Bay in North America and Barents and Kara Seas in Eurasia during retreat phases through sea‐level feedback. Our results also indicate that solid Earth deformation influences the relative sensitivity of the North American and Eurasian ice sheets to climate and thus the timing and magnitude of their fluctuations throughout the last glacial cycle.
Recreating the Horizontal Magnetic Field at Colaba During the Carrington Event With Geospace Simulations
Authors: Blake Seán P. , Pulkkinen Antti , Schuck Peter W. , Glocer Alex , Oliveira Denny M. , Welling Daniel T. , Weigel Robert S. , Quaresima Gary 
Published: March 2021

AbstractAn intriguing aspect of the famous September 2, 1859 geomagnetic disturbance (or “Carrington” event) is the horizontal magnetic (BH) data set measured in Colaba, India (magnetic latitude approximately 20°N). The field exhibits a sharp decrease of over 1,600 nT and a quick recovery of about 1,300 nT, all within a few hours during the daytime. The mechanism behind this has previously been attributed to magnetospheric processes, ionospheric processes or a combination of both. In this study, we outline our efforts to replicate this low‐latitude magnetic field using the Space Weather Modeling Framework. By simulating an extremely high pressure solar wind scenario, we can emulate the low‐latitude surface magnetic signal at Colaba. In our simulation, magnetospheric currents adjacent to the near‐Earth magnetopause and strong Region 1 field‐aligned currents are the main contributors to the large Colaba BH. The rapid recovery of BH in our simulated scenario is due to the retreat of these magnetospheric currents as the magnetosphere expands, as opposed to ring current dynamics. In addition, we find that the scenario that best emulated the surface magnetic field observations during the Carrington event had a minimum calculated Dst value between −431 and −1,191 nT, indicating that Dst may not be a suitable estimate of storm intensity for this kind of event.