bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cortisol, Temperament and Serotonin in Karate Combats: An Evolutionary Psychobiological Perspective
Authors: Ponzi Davide , Dadomo Harold , Filonzi Laura , Palanza Paola , Pelosi Annalisa , Ceresini Graziano , Parmigiani Stefano , Marzano Francesco Nonnis 
Published: October 2021

Abstract
Objectives
There is evidence suggesting that in martial arts competitions athletes characterized by higher anxiety and harm avoidance may be more likely to lose a fight. This psychological profile has been hypothesized to explain in part the observation that cortisol is higher in losers before and in response to a competition. An important research target that needs further exploration is the identification of phenotypic traits that can be helpful in predicting athletes’ performance. Here we present a brief description of the theoretical bases that drives our research in the evolutionary psychobiology of sports and illustrate preliminary data on the relationship between the 5HTTLPR genotype, salivary cortisol, temperament and competition.

Methods
Sixty-five healthy male non-professional athletes provided saliva samples 10 min before and after a kumite session and filled out the Tridimensional Personality Questionnaire.

Results
Salivary cortisol levels 10 min before the competition were higher in losers and in athletes with the S allele. Temperament was associated with competition outcome and cortisol: losers were characterized by higher scores of harm avoidance and harm avoidance was positively correlated with cortisol levels.

Conclusions
The results confirm previous findings linking temperamental traits, pre-and post- competition physiological stress response with competition outcome in kumite fight. Moreover, they indicate an association between the 5HTTLPR polymorphism and pre-competition salivary cortisol, thus providing a preliminary but non-conclusive evidence on the role played by the 5HTTLPR genotype as a vulnerability factor in sport competition.
H-Clinoptilolite as an Efficient and Low-Cost Adsorbent for Batch and Continuous Gallium Removal from Aqueous Solutions
Authors: Sáez P. , Rodríguez A. , Gómez J. M. , Paramio C. , Fraile C. , Díez E. 
Published: October 2021

AbstractIn this paper, the gallium (III) ions’ adsorption onto protonated clinoptilolite (H-CLP) was investigated both in batch and fixed-bed column experiments. Regarding batch experiments, the influence of some parameters such as adsorbent dosage, size particle, and temperature was studied, determining that a dosage of 10 g/L for an initial pollutant concentration of 40 mg/L leads to a removal percentage over 85% regardless of particle size and temperature. On the other hand, adsorption of gallium onto H-CPL is an endothermic and spontaneous process in the studied temperature range, concluding that the maximum adsorption capacity was 16 mg/g for 60 °C. Concerning to the effect of the presence of other cations in solution, such as Na+, K+, or Ca2+, gallium adsorption capacity only drops by 20%, although the initial concentration of other cations in the solution is 50 times higher than gallium concentration. This means that clinoptilolite has a high affinity for gallium which can be very favorable for further selectivity tests. A crucial factor for this high selectivity could be the protonation of clinoptilolite which allows working without modifying the pH of the aqueous solution with acid. In the fixed-bed experiments, breakthrough curves were obtained, and the effect of operation variables was determined. A breakpoint value of 254 min for 64 g of adsorbent and flow rate of 9.0 mL/min (7.0 BV/h) were obtained, when treating a pollutant volume of 33 BV. Additionally, the breakthrough curves were fitted to different models to study the particle size effect, being the best fit corresponding to the Adams–Bohart model. This fact confirmed the influence of particle size on adsorption kinetics.
Graphical Abstract
Moving from plagiarism police to integrity coaches: assisting novice students in understanding the relationship between research and ownership
Authors: Vaccino-Salvadore Silvia , Hall Buck Rachel 
Published: October 2021

AbstractMuch of the discourse surrounding plagiarism is one of fear—a fear of being caught and punished, but many plagiarism examples happen unintentionally as students struggle with a new language, new ideas, and new communities in tertiary education. Specifically, many students are challenged with the task of writing a research paper, which involves finding academic sources, reading those sources to answer a research question, and integrating direct quotations and paraphrasing. Because novice writers often struggle with these skills, what is a developmental stage is instead interpreted as plagiarism. Much of the discussion of plagiarism involves implicit and explicit definitions of ownership, but there is little research about how students understand the concept of ownership in relation to ideas and language. In this qualitative study, we present data from 18 international students at an American-style university in the Middle East who write an introductory research paper as part of a composition course. Results show that perceptions of plagiarism changed in relation to owning ideas, owning language, and owning time spent on the research process and that distinguishing these boundaries is often difficult for students even within their own final research papers. We suggest teaching more robust note-taking strategies, discussing ownership in terms of a writer’s choices in guiding readers through the paper, and creating an environment where students can understand the complexities of plagiarism rather than simply fearing being caught.
The feasibility of conducting acute sarcopenia research in hospitalised older patients: a prospective cohort study
Authors: Welch Carly , Greig Carolyn , Majid Zeinab , Masud Tahir , Moorey Hannah , Pinkney Thomas , Jackson Thomas 
Published: October 2021

Abstract
Purpose
To assess feasibility of conducting acute sarcopenia research in complex populations of hospitalised older adults.

Methods
Patients ≥ 70 years old were recruited to three cohorts: elective colorectal surgery, emergency (abdominal) surgery, medical patients with infections. Participants were recruited to the elective cohort in preoperative assessment clinic, and acutely admitted participants from surgical and medical wards at the Queen Elizabeth Hospital Birmingham. Serial measures of muscle quantity (ultrasound quadriceps, bioelectrical impedance analysis), muscle function (hand grip strength, physical performance), and questionnaires (mini-nutritional assessment, physical function) were performed at baseline, within 7 (± 2) days of admission/surgery, and 13 (± 1) weeks post-admission/surgery. Feasibility outcomes were assessed across timepoints including recruitment and drop-out rates, and procedure completion rates.

Results
Eighty-one participants were recruited (mean age 79, 38.3% females). Recruitment rates were higher in elective (75%, 24/32) compared to emergency surgery (37.2%, 16/43), and medical participants (45.1%, 41/91; p = 0.003). Drop-out rates varied from 8.3 to 19.5% at 7 days, and 12.5–43.9% at 13 weeks. Age and gender did not differ between patients assessed for eligibility, approached, or recruited. Completion rates were highest for ultrasound quadriceps (98.8%, 80/81 across all groups at baseline). Gait speed completion rates were lower in medical (70.7%, 29/41) compared to elective participants (100%, 24/24) at baseline.

Conclusion
Higher participation refusal and drop-out rates should be expected for research involving recruitment of participants from the acute setting. Assessment of muscle quantity/quality through ultrasound is recommended in early-stage trials in the acute setting, where completion rates of physical performance testing are expected to be lower.
Insights from a novel, user-driven science transfer program for resource management
Authors: Hinderer J. L. M. , Blevins Z. , Cooke S. J. , Dunlop E. , Robinson K. F. , Stang D. L. , Stewart T. J. , Tyson J. T. , Welsh A. B. , Young N. , Muir A. M. 
Published: October 2021

AbstractResearch results are often not easily accessible or readily digestible for decision-making by natural resource managers. This knowledge-action gap is due to various factors including the time lag between new knowledge generation and its transfer, lack of formal management structures, and institutional inertia to its uptake. Herein, we reflect on the Great Lakes Fishery Commission’s Science Transfer Program and its evolution from ‘Mode 1’ (i.e., scientists conduct research autonomously) toward ‘Mode 2’ (i.e., co-production of knowledge with practitioners) knowledge production to understand and overcome the knowledge-action gap. Six success factors and strategies and tactics used to achieve those factors were critical to the shift from Mode 1 to Mode 2: (1) dedicate funding and staff support; (2) obtain top-down commitment from organizational leadership; (3) break down silos; (4) build relationships through formal and informal interactions; (5) emphasize co-production in program and project implementation; and (6) obtain buy-in among relevant actors. By way of three project case studies, we highlight knowledge transfer approaches, products, and lessons learned. We anticipate this contribution will benefit those working on knowledge mobilization, particularly in boundary-spanning organizations, and those involved in resource program management, administration, and design; it is also intended for resource managers seeking to have their science and information needs met more effectively.
A hybrid approach to identifying and assessing interactions between climate action (SDG13) policies and a range of SDGs in a UK context
Authors: Stevenson Samuel , Collins Alexandra , Jennings Neil , Köberle Alexandre C. , Laumann Felix , Laverty Anthony A. , Vineis Paolo , Woods Jeremy , Gambhir Ajay 
Published: October 2021

AbstractIn 2015 the United Nations drafted the Paris Agreement and established the Sustainable Development Goals (SDGs) for all nations. A question of increasing relevance is the extent to which the pursuit of climate action (SDG 13) interacts both positively and negatively with other SDGs. We tackle this question through a two-pronged approach: a novel, automated keyword search to identify linkages between SDGs and UK climate-relevant policies; and a detailed expert survey to evaluate these linkages through specific examples. We consider a particular subset of SDGs relating to health, economic growth, affordable and clean energy and sustainable cities and communities. Overall, we find that of the 89 UK climate-relevant policies assessed, most are particularly interlinked with the delivery of SDG 7 (Affordable and Clean Energy) and SDG 11 (Sustainable Cities and Communities) and that certain UK policies, like the Industrial Strategy and 25-Year Environment Plan, interlink with a wide range of SDGs. Focusing on these climate-relevant policies is therefore likely to deliver a wide range of synergies across SDGs 3 (Good Health and Well-being), 7, 8 (Decent Work and Economic Growth), 9 (Industry, Innovation and Infrastructure), 11, 14 (Life Below Water) and 15 (Life on Land). The expert survey demonstrates that in addition to the range of mostly synergistic interlinkages identified in the keyword search, there are also important potential trade-offs to consider. Our analysis provides an important new toolkit for the research and policy communities to consider interactions between SDGs, which can be employed across a range of national and international contexts.
Identifying key ethical debates for autonomous robots in agri-food: a research agenda
Authors: Ryan Mark , van der Burg Simone , Bogaardt Marc-Jeroen 
Published: October 2021

AbstractAgribusinesses are investing in different forms of AI robots, as there is a lot of hope that these machines will help meet the challenges within the agricultural industry, which is to efficiently produce more food for a growing world population. AI robots are expected to enhance production, while compensating for lack of manpower, reducing production costs, taking over unattractive (risky, heavy, and dirty) jobs and reducing the burden of food production on the environment. In spite of these promises, however, AI robots for agri-food also give rise to ethical questions and concerns, which have been little researched and discussed until now. To fill this gap, we developed a research agenda for future research in this area. To do this, we opened our analysis to focus on ethics AI robots generally to specifically identify which of these issues are most relevant to agro-robots. The question we want to find an answer to is: what are the most relevant ethical questions raised about AI robots for robots developed for the agri-food sector? And which questions are not mentioned in the literature, which are particularly relevant for agro-robots? Our paper will provide an overview over the key issues and areas which deserve further elaboration to come to a more mature ethics of AI agro-robots.
Facing Counterfeit Medications in Sexual Medicine. A Systematic Scoping Review on Social Strategies and Technological Solutions
Authors: Sansone Andrea , Cuzin Béatrice , Jannini Emmanuele A. 
Published: October 2021

AbstractIntroductionThe counterfeit phenomenon is a largely under-reported issue, with potentially large burden for healthcare. The market for counterfeit drugs used in sexual medicine, most notably type 5 phosphodiesterase inhibitors (PDE5i), is rapidly growing.AimsTo report the health risks associated with the use of counterfeit medications, the reasons driving their use, and the strategies enacted to contain this phenomenon.MethodsA systematic scoping review of the literature regarding counterfeit PDE5i was carried between January and June 2021, then updated in August 2021.Main Outcome MeasureWe primarily aimed to clarify the main drivers for counterfeit PDE5i use, the health risks associated, and the currently available strategies to fight counterfeiters.ResultsOne hundred thirty-one records were considered for the present scoping review. Production of fake PDE5i is highly lucrative and the lacking awareness of the potential health risks makes it a largely exploitable market by counterfeiters. Adulteration with other drugs, microbial contamination and unreliable dosages make counterfeit medications a cause of worry also outside of the sexual medicine scope. Several laboratory techniques have been devised to identify and quantify the presence of other compounds in counterfeit medications. Strategies aimed at improving awareness, providing antitampering packaging and producing non-falsifiable products, such as the orodispersible formulations, are also described.Clinical implicationsImproving our understanding of the PDE5i counterfeit phenomenon can be helpful to promote awareness of this issue and to improve patient care.Strengths & LimitationsDespite the systematic approach, few clinical studies were retrieved, and data concerning the prevalence of counterfeit PDE5i use is not available on a global scale.ConclusionThe counterfeit phenomenon is a steadily growing issue, with PDE5i being the most counterfeited medication with potentially large harmful effects on unaware consumers.
Common seasonal respiratory viral infections in children before and during the coronavirus disease 2019 (COVID-19) pandemic
Authors: Song Xiaoyan , Delaney Meghan , Shah Rahul K. , Campos Joseph M. , Wessel David L. , DeBiasi Roberta L. 
Published: October 2021

AbstractObjectives:To describe the incidence of seasonal respiratory viral infections (s-RVIs) before and during the coronavirus disease 2019 (COVID-19) pandemic and to compare virus-specific patient outcomes in pediatric patients.Design:A retrospective cross-sectional study including patient admissions to the Children’s National Hospital between October 1, 2015, and December 31, 2020.Results:Among 12,451 patient admissions between March 15 and December 31, 2020 (cohort 1), 8,162 (66%) were tested for severe acute respiratory coronavirus virus 2 (SARS-CoV-2), and 249 (2.0%) were positive. Among 10,986 patient admissions between April 1 and December 31, 2020 (cohort 2), 844 (8%) were tested for s-RV upon admission and 160 were positive. Thus, 1.5% of patient admissions were associated with laboratory-confirmed s-RVIs. Among the 49,901 patient admissions during a viral season between October 1, 2015, and March 31, 2020 (cohort 3), 7,539 (15%) were tested for s-RV upon admission and 4,531 were positive; thus, 9.0% of patient admissions were associated with laboratory-confirmed s-RVIs. hHRV/rENT was the most detected virus, but the detection rate decreased substantially (31% vs 18%; P < .001) during the COVID-19 pandemic. No patients had RSV, influenza, hMPV, hPIV, or hCoV detected upon admission after April 21, 2020. The 3 patient cohorts had no statistically significant difference in the percentage of ICU admissions (10.8% vs 15.0% vs 14.2%; P > .05) or death at discharge (0.8% vs 0.6% vs 0.5%; P > .05).Conclusions:Compared to COVID-19, s-RVI cases were associated with a higher proportion of inpatient admissions but were similar in ICU admission and death rates in hospitalized pediatric patients. Public health interventions for preventing COVID-19 were highly effective in preventing pediatrics s-RVIs.
A New Electorate? Explaining the Party Preferences of Immigrant-Origin Voters at the 2017 Bundestag Election
Authors: Goerres Achim , Mayer Sabrina Jasmin , Spies Dennis Christopher 
Published: October 2021

AbstractImmigrants now constitute a sizeable and rapidly growing group among many Western countries' electorates, but analyses of their party preferences remain limited. Theoretically, immigrants' party preferences might be explained with both standard electoral theories and immigrant-specific approaches. In this article, we rigorously test both perspectives against each other using the most recent data from Germany. Applying the Michigan model, with its three central explanatory variables – party identification, issue orientations and candidate evaluations – to the party preferences of immigrant-origin and native voters, we find that this standard model can explain both groups well. In contrast, we find no direct effects of the most prominent immigrant-specific variables, and neither do these meaningfully moderate the Michigan variables. However, we find strong formative effects on the presence of political attitudes and beliefs: immigrants with a longer time spent in Germany, a stronger German identity and less experience of discrimination report significantly fewer item non-responses for the Michigan model's main explanatory variables.
ASSESSING THE IMPLICATIONS OF SCHREMS II FOR EU–US DATA FLOW
Authors: Murphy Maria Helen 
Published: October 2021

AbstractWith the constant flow of data across jurisdictions, issues regarding conflicting laws and the protection of rights arise. This article considers the EU–US data transfer relationship in the aftermath of the decision in Data Protection Commissioner v Facebook Ireland and Maximillian Schrems where the Court of Justice of the European Union (CJEU) invalidated an EU–US data transfer agreement for the second time in just five years. This judgment continues the line of cases emphasising the high value the Court places on securing EU personal data in accordance with EU data protection standards and fundamental rights. This article assesses the implications of the ruling for the vulnerable EU–US data transfer relationship.
Does Medicaid expansion influence county health spending? A case of New York counties
Authors: Noh Shihyun , Park Ji-Hyung 
Published: October 2021

AbstractWe investigated the impacts of Medicaid expansion on New York county total health spending and specifics of health spending, including health services, public health facilities and public health administration. Little research considered the financial effect of Medicaid expansion on local governments while well reported are its influences on uninsured rates and health services utilization. New York counties have contributed to health in their boundaries by providing or funding public health services, and supporting a part of the non-federal share of Medicaid expenditures and uncompensated care. Medicaid expansion can reduce the size of county expenditures for health by enrolling more previously uninsured population in the program and offering more generous federal funding for the expanded Medicaid. We offer empirical evidence that Medicaid expansion was associated with reduced county health spending.
Embedded smart sensor dipole antennas for real-time damage assessment, humidity, and temperature monitoring in reinforced and non-reinforced concrete structures
Authors: Ozturk Murat 
Published: October 2021

AbstractIn this study, a dipole antenna is designed for real-time damage assessment, humidity, and temperature monitoring in reinforced and non-reinforced concrete structures. The antenna-based sensor is embedded into reinforced and non-reinforced concrete beams to assess electromagnetic measurements. Reflection parameter S11 in dB values and resonant frequencies of the embedded antenna are evaluated to detect damage, humidity, and temperature changes. The exploratory results show that as deformation increases in reinforced concrete, resonance frequency values decrease and S11 values increase. The load and resonance frequency values showed very close trends as deformation increases in the beam. In water content sensing experiments, the S11 in dB values of the antenna decrease as the humidity increases for concrete specimens while the resonance frequency values increase as the humidity increases for the reinforced concrete specimen. Elevated temperature sensing experimental results show that the resonance frequency values of the antenna decrease as the temperature of the specimen increases for concrete specimens while the S11 in dB values increase as the temperature of the specimen increases for reinforced concrete specimen.
Single-cell RNA sequencing reveals cell heterogeneity and transcriptome profile of breast cancer lymph node metastasis
Authors: Xu Kun , Wang Runtian , Xie Hui , Hu Longfei , Wang Cong , Xu Jiali , Zhu Chengjun , Liu Yiqiu , Gao Fangyan , Li Xintong , Wang Cenzhu , Huang Jinyi , Zhou Wenbin , Zhou Guohua , Shu Yongqian , Guan Xiaoxiang 
Published: October 2021

AbstractMolecular mechanisms underlying breast cancer lymph node metastasis remain unclear. Using single-cell sequencing, we investigated the transcriptome profile of 96,796 single cells from 15 paired samples of primary tumors and axillary lymph nodes. We identified nine cancer cell subclusters including CD44 + / ALDH2 + /ALDH6A1 + breast cancer stem cells (BCSCs), which had a copy-number variants profile similar to that of normal breast tissue. Importantly, BCSCs existed only in primary tumors and evolved into metastatic clusters infiltrating into lymph nodes. Furthermore, transcriptome data suggested that NECTIN2-TIGIT-mediated interactions between metastatic breast cancer cells and tumor microenvironment (TME) cells, which promoted immune escape and lymph node metastasis. This study is the first to delineate the transcriptome profile of breast cancer lymph node metastasis using single-cell RNA sequencing. Our findings offer novel insights into the mechanisms underlying breast cancer metastasis and have implications in developing novel therapies to inhibit the initiation of breast cancer metastasis.