bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impaired Pulmonary Function in Patients with Chronic Neck Pain
Authors: Awadallah Mohamed Fawzi , Sobh Eman , Shendy Mohamed Abdelhalim , Al-Shenqiti Abdullah M. , Al-Jeraisi Talal M. , Eweda Reda S. 
Published: June 2021

Background:
Neck pain is a common problem in the medical practice, and the limited movement of the neck muscles can result in impaired chest movement. This study aimed to investigate the relationship between neck pain and pulmonary function using spirometry.

Methods:
We included 75 patients with chronic neck pain and 75 age- and sex-matched healthy controls. We performed spirometry and recorded forced-vital capacity (FVC), forced expiratory volume in the first second of FVC (FEV1), forced expiratory flow at 25%–75% (FEF 25–75), and peak expiratory flow rate (PEFR). We also measured the neck active range of motion in all positions (flexion, extension, lateral flexion, and rotation) and administered the Neck Disability Index (NDI) and Visual Analog Scale (VAS) for pain.

Results:
Neck movements were significantly limited in all directions in patients with chronic neck pain. Pulmonary function (FVC, FEV1, FEF25–75, and PEFR) was significantly lower, and FEV1/ FVC was significantly higher in the neck pain group compared with the control group. In the neck pain group, restrictive pattern in spirometry was found in 39 participants (52%). The pulmonary function parameters (FVC, FEV1, FEF25–75, and PEFR) had a significant positive linear relationship with neck movement and a significant negative linear relationship with VAS and NDI scores.

Conclusions:
Patients with chronic neck pain had limited pulmonary function, which was related to a limited range of cervical movement.
Implementasi Model Pembelajaran Reciprocal Teaching untuk Meningkatkan Motivasi dan Hasil Belajar Pemrograman Dasar Kelas X TKJ SMK Negeri 1 Painan
Authors: Zuryana Zuryana 
Published: June 2021

Penelitian ini dilatar belakangi dengan adanya fenomena yang peneliti temukan dilapangan yaitu rendahnya motivasi belajar siswa dikarenakan siswa hanya mendengarkan dan mencatat, sehingga dalam hal ini mempengaruhi hasil dan motivasi belajar siswa. Penelitian ini bertujuan untuk mengetahui implementasi model pembelajaran Reciprocal teaching untuk meningkatkan motivasi belajar siswa dan KKM Pemrrograman Dasar Kelas X TKJ SMK Negeri 1 Painan . Subjek penelitian ini adalah siswa kelas X TKJ SMK Negeri 1 Painan tahun ajaran 2020/ 2021, dengan menggunakan model penelitian tindakan kelas (PTK) bersifat kolaboratif, dengan teknik analisis data kualitatif dan kuantitatif. Penelitian ini menggunakan II siklus dan tiap siklus dua kali pertemuan. Kegiatan tiap siklus terdiri dari: perencanaan, pelaksanaan, pengamatan dan refleksi.. Berdasarkan hasil lembar observasi selama penelitian, menunjukan bahwa rata-rata persentase motivasi belajar pada siklus I adalah 58% dalam kategori baik, rata-rata persentase motivasi belajar pada siklus II 77% dalam kategori sangat baik. Peningkatan hasil belajar siswa kelas X TKJ SMK Negeri 1 Painan dilihat dari ketuntasan klasikal pada tes siklus I dan tes siklus II berturut-turut 41% dan 81%.Kesimpulan dari penelitian ini adalah implementasi model pembelajaran reciprocal teaching dapat meningkatkan motivasi dan hasil belajar siswa
Det sammanflätade intresset
Authors: Andersson-Skog Lena , Eriksson Martin 
Published: June 2021

This article focuses on the interaction between the state and Swedish banks during the establishment of two institutes for small business credit, AB Industrikredit and AB Företagskredit, between 1958 and 1962. These institutes were established as intermediaries between the supplementary pension system and the credit market. We have been able to elucidate this process by the Swedish Bankers’ Association granting us privileged access to archival material on these negotiations.
It is demonstrated that the strong ideological conflict characterizing the parliamentary debate on the supplementary pensions system did not spill over into the system being implemented within the financial sector as this was organized through the examined credit institutes. Instead, the banks and the state were able to negotiate through established channels and arenas for business-government relations in the financial sector. Even if the parties initially exhibited mistrust based on different historical interpretations of the market for small business credit, they also recognized the degree of change that would be brought on by the supplementary pension system with regard to the financial markets and capital formation as a whole. Hence, they downplayed ideological differences and strived to reach an outcomethat was mutually beneficial in its final form. A crucial indication of this consensus is that fifty percent of each institute was owned by the state while the other fifty percent was owned by the banks.
¿Cómo se definen relevancia, pertinencia y demanda de la investigación científico-tecnológica? Agendas orientadas y evaluación académica en los Proyectos de Desarrollo Tecnológico y social (PDTS)
Authors: Alonso Mauro , Nápoli Mariángela 
Published: June 2021

Este artículo propone analizar una herramienta de política científica lanzada en el año 2012, los Proyectos de Desarrollo Tecnológico y Social (PDTS), abordada en trabajos recientes en el campo Ciencia, Tecnología y Sociedad (CTS), a la luz de nuevos hallazgos y aportes bibliográficos. Puntualmente, abordaremos dos recursos que resignificaron a los PDTS y permiten brindar una mirada crítica a las políticas científicas actuales: la evaluación y sus actores involucrados, y la definición de criterios de novedad local, relevancia, pertinencia y demanda que componen el contenido de la ciencia producida. La metodología elegida se basa en el análisis descriptivo de los documentos y revisiones teóricas de trabajos previos. Como posibles conclusiones, consideramos que los PDTS permitieron pensar contenidos de trabajo e investigación científica que se encontraban determinados por los actores involucrados en la evaluación que no provenían, solamente, del mundo académico; de esta forma, la relevancia y/o pertinencia de los temas podría estar dada por un sector extra-académico que prioriza fines de utilidad social.
Carole King's Tapestry
Authors: Glass Loren 
Published: June 2021

Carole King’s Tapestry is both an anthemic embodiment of second-wave feminism and an apotheosis of the Laurel Canyon singer-songwriter sound and scene. And these two elements of the album’s historic significance are closely related insofar as the professional autonomy of the singer-songwriter is an expression of the freedom and independence women of King’s generation sought as the turbulent sixties came to a close.
Aligning King’s own development from girl to woman with the larger shift in the music industry from teen-oriented singles by girl groups to albums by adult-oriented singer-songwriters, this volume situates Tapestry both within King’s original vision as the third in a trilogy (preceded by Now That Everything’s Been Said and Writer) and as a watershed in musical and cultural history, challenging the male dominance of the music and entertainment industries and laying the groundwork for female dominated genres such as women’s music and Riot Grrrl punk.
Allicin depresses biological activities of pancreatic cancer cells by regulating miRNA-339-5p/ZNF-689 axis
Authors: Yu Zeqian , Zhao Susu 
Published: June 2021

IntroductionThe aim of this study was to discuss Allicin’s anti-tumor effects and relative in pancreatic cancer cell via vitro and vivo study.Material and methodsUsing PANC-1 and Hs766T cell as research cell lines in our study. The PANC-1 abd GS799T cell were respectively treated with difference concentrations of Allicin. In next step, the PANC-1 abd GS799T cell were transfected with si-miRNA-339-5p which knockdown miRNA-339-5p. The cells were treated with difference concentration of Allicin. Measuring cell proliferation, apoptosis, invasion and migration by MTT, EDU, flow cytometry, TUNEL, transwell and wound healing assay. Relative gene (miRNA-339-5p, ZNF-689, Caspase-3, Caspase-8, E-cadherin and Vimentin) and protein (ZNF-689, Caspase-3, Caspase-8, E-cadherin and Vimentin) expression were evaluated by RT-qPCR and WB assay.ResultsAllicin had effects to suppress PANC-1 and Hs766T cell biological activities including cell proliferation, invasion and migration with cell apoptosis significantly increasing, however, with si-miRNA-339-5p which inhibit miRNA-339-5p expression transfection, the cells biological activities enhancing with cell apoptosis depressing, Compared with NC group, miRNA-339-5p, Caspase-3, Caspase-8 and E-cadherin expression were significantly increased and ZNF-689 and Vimentin expression were significantly depressed in Allicin treated groups, however, with miRNA-339-5p inhibitor transfection, the Allicin’s effects significantly disappear.ConclusionsAllicin had anti-tumor effect to pancreatic cancer biological activities via regulation miRNA-339-5p/ZNF-689 axis in vitro study.
Assessment of cardiac function and subclinical atherosclerosis in children with systemic lupus erythematosus
Authors: Wagdy Reham , El Shafie Mohammed , El-Kersh Mohie 
Published: June 2021

IntroductionJuvenile onset systemic lupus erythematosus (JSLE) is an autoimmune disease associated with high cardiovascular morbidity. The purpose of the study was to assess cardiac function and subclinical atherosclerosis among children with SLE and to establish risk factors.Material and methodsData on thirty children with SLE followed up at Alexandria Main Children Hospital were collected and compared to thirty matched controls. The collected data were about demographics, systemic examination and laboratory findings. However, all participants were subjected to echocardiography, pulsed wave tissue Doppler (PWTD) and sonographic assessment of intima media thickness of the abdominal aorta (aIMT) and carotid arteries (cIMT).ResultsThe patient group with mean age of 11.3 ±2 years and mean duration of disease 3.2 ±2.3 years included 63.3% (n = 19) hypertensive cases with no heart failure. High cholesterol values were reported in 30%. The main findings of the imaging studies of patients showed significantly low ejection fraction (EF) (57.9 ±5.8, p < 0.001) and low mitral annular velocities at septal and lateral walls at peak systole (Sm) and peak early diastolic filling (Em) (p < 0.001). Also there were significantly high aIMT (1.1 ±0.3) and cIMT (0.5 ±0.7) for patients. The duration of the disease and aIMT were significant risk factors that negatively affect Sm and Em of lateral wall (p ≤ 0.05).ConclusionsIn JSLE, impaired LV function and subclinical atherosclerosis were prevalent specially among children with longer disease duration which highlight the need for periodic checkup by ultrasonography and PWTD.
The Effectiveness of Human Resource Development Management in Efforts to Improve The Quality of Education in SD Negeri 90 Ogan Komering Ulu
Authors: Dauzar Dauzar , Fitria Happy , Putra Alhadi Yan 
Published: June 2021

This study aims to determine the effectiveness of human resource development management to increase quality at SD Negeri 90 Ogan Komering Hulu (OKU). This research is a qualitative research with qualitative descriptive approach. The data obtained were collected through observation, interview and documentation techniques. The results showed that the human resource development steps carried out at SD Negeri 90 OKU were carried out in 7 steps, namely compiling programs, determining needs, determining targets, determining programs, identifying learning principles, program implementation and evaluation of program implementation. Human resource management at SD Negeri 90 OKU, both in terms of quality improvement, implementation, supporting factors and the quality of education have been running optimally.
KOMPARASI HASIL BELAJAR MAHASISWA MENGIKUTI KULIAH DARING MATA KULIAH K3 ANTARA MAHASISWA YANG TINGGAL DI KOTA SAMARINDA DAN LUAR KOTA SAMARINDA TAHUN 2021
Authors: Sastrini Yovita Erin , Herni Pertiwi Gracia 
Published: June 2021

Penelitian ini menguraikan tentang perbandingan hasil belajar mahasiswa dalam mengikuti kuliah daring antara mahasiswa yang tinggal di Wilayah Kota Samarinda dan di luar Wilayah Kota Samarinda (Pelosok). Tujuan penelitian ini adalah 1) mengetahui hasil belajar mahasiswa yang mengikuti kuliah daring Mata Kuliah K3 di Kota Samarinda, 2) mengetahui hasil belajar mahasiswa yang mengikuti kuliah daring Mata Kuliah K3 di luar Kota Samarinda, 3) mengetahui perbedaan hasil belajar antara mahasiswa yang mengikuti kuliah daring Mata Kuliah K3 di Kota Samarinda dan mahasiswa yang mengikuti kuliah daring di luar Kota Samarinda.Penelitian ini merupakan penelitian komparasi dengan pendekatan kuantitatif. Sampel yang digunakan dalam penelitian ini adalah 15 orang mahasiswa yang berdomisili di Samarinda, dan 15 orang mahasiswa yang berdomisili di luar samarinda yang saat kuliah dilaksanakan tidak berada di Kota Samarinda. Data hasil belajar diperoleh berdasarkan evaluasi hasil belajar mahasiswa pada Mata Kuliah K3 di semester enam. Hasil penelitian menunjukkan bahwa rata-rata nilai mahasiswa yang mengikuti kuliah daring di kota Samarinda adalah 83.27, sedangkan rata-rata nilai mahasiswa yang mengikuti kuliah di luar Kota Samarinda adalah 81.87. Hasil uji hipotesis menggunakan Mann Whitney menunjukkan bahwa tidak ada perbedaan hasil belajar antara mahasiswa yang mengikuti kuliah di wilayah Kota Samarinda dengan mahasiswa yang mengikuti kuliah di luar kota samarinda. Penelitian selanjutnya diharapkan dapat mengembangkan penelitian ini melalui penelitian kualitatif untuk menggali pengalaman mahasiswa dalam mengikuti kuliah daring selama masa Pandemi Covid-19.
Plagas asociadas a los cítricos en Chinandega, Nicaragua, 2018
Authors: Jiménez Martínez Edgardo , Méndez López Elber 
Published: June 2021

Los cítricos (Citrus spp. L.) representan en Nicaragua una fuente de divisa y generación de empleo porque, no existe un reporte formal sobre la ocurrencia poblacional de insectos asociados a los cítricos. El presente estudio tuvo el propósito de determinar la fluctuación poblacional de insectos plagas y benéficos en cítricos. El estudio se realizó en los municipios de Chinandega y Chichigalpa, departamento de Chinandega, en el período de abril a septiembre del 2014, el levantamiento de datos fue en seis fincas, en cada finca se ubicaron seis trampas, tres trampas de caída libre (Pitfall traps) para la captura de insectos rastreros, y tres trampas de galón con melaza para la captura de insectos voladores, los insectos colectados se enviaron al laboratorio de entomología de la UNA para su identificación hasta el nivel de especie, se evaluó el número de insectos por familia y a los datos se le realizó un análisis de varianza, la diversidad y abundancia se estimó utilizando el índice de diversidad Shannon-Weaver, para las diferentes familias de la población. Los resultados obtenidos demostraron que las principales familias de insectos asociados al cultivo de cítricos son, Formicidae, Syrphidae, Vespidae, Tachinidae, Carabidae, Apidae, Tenebrionidae, Chrysopidae, Sarcophagidae y de los arácnidos se encontró a la familia Araneidae, se concluye que La mayor riqueza de insectos asociados a los cítricos fue encontrada en la finca Farid seguida de las fincas Mariaelsa y Pañueleta, esto es debido a baja aplicación de pesticida, presencia de abundante vegetación silvestre y cercanía con otras especies de cultivadas en la zona .
Kroniek rechtspraak mededingingsrecht
Authors: Belhadj E. , Dekker C.T. 
Published: June 2021

Kroniek rechtspraak mededingingsrecht
In deze kroniek staan besluiten en andere handelingen van de Autoriteit Consument & Markt (ACM) voor wat betreft de toepassing van de Mededingingswet (Mw) in de zorgsector centraal. Daarnaast komt een uitspraak van het College van Beroep voor het bedrijfsleven (CBb) aan bod. Deze kroniek heeft betrekking op de periode 1 november 2018 tot en met 31 december 2020.
Click Reactions in Polymer Synthesis
Authors: Huang Die , Qin Anjun , Tang Ben Zhong 
Published: June 2021

Abstract
Click reactions, with remarkable merits including high efficiency, atom economy, mild reaction conditions, good functionality tolerance, simple isolation process, and regio‐ and/or stereoselectivity, have drawn intense attention of polymer chemists and found widespread applications in polymer synthesis. Besides the famous Cu(I)‐catalyzed azide–alkyne click reaction, plentiful click reactions, such as Diels–Alder, thiol‐based, nonaldol carbonyl, amino‐yne, hydroxyl–yne, and sulfur(VI) fluoride‐exchange click reactions, have also been introduced into the field of polymer chemistry. With these efficient click reactions in hand, diverse functional groups can be readily incorporated into polymer chains to endow them with desired functionalities. Copolymers with complex structures, such as block, graft, star, and cyclic polymers, can be synthesized using click reaction as polymer conjugation method. These click reactions have also been developed into facile polymerization techniques, that is, click polymerization, for the direct synthesis of linear, hyperbranched, and cross‐linked polymers with various properties. This article intends to give a brief summary of click reactions applied in polymer synthesis, including preparation of polymers and postpolymerization modification of preformed polymers.
Graphitic Carbon Nitride: A Promising Polymer with Widespread Applications
Authors: Asadzadeh‐Khaneghah Soheila , Habibi‐Yangjeh Aziz 
Published: June 2021

Abstract

Graphitic carbon nitride (g‐C
3
N
4
), as an amazing two‐dimensional polymer, displayed vast interdisciplinary consideration as a metal‐free, robust, and visible‐light‐active material with diverse applications, and it has introduced a novel research hotspot. This appealing polymer endows an excellent perspective in various sciences, thanks to its moderate energy gap, significant optical and electronic features, and supreme physicochemical and thermal durability. Moreover, g‐C
3
N
4
can be easily fabricated by attainable nitrogen and carbon sources in nitrogen‐rich environments. These features have led to the usage of this polymer in hydrogen production, contaminant degradation, carbon dioxide reduction, N
2
fixation, supercapacitors, lithium‐ion batteries, fuel cells, and sensing. This article gives a general review about the preparation routes of g‐C
3
N
4
polymer and the optical absorption characteristics and highlights their applications in different arena.
High Dielectric Constant (Highk) Polymer Composites
Authors: Chen Jie , Jiang Pingkai , Huang Xingyi 
Published: June 2021

AbstractHigh dielectric constant (highk) polymer composites are promising materials used in transistors, pulsed power systems, artificial muscles, energy harvesting and storage, and electrocaloric cooling applications. Based on the type of filler used, they can generally be classified as nonconductive filler (ceramic) based, conductive filler based, and a hybrid type containing both nonconductive and conductive fillers. In this article, the physical models and development of highkpolymer composites are briefly illustrated. Particularly, the main factors that affect the dielectric properties of polymer composites, including filler size, shape, dispersion state, orientation, surface properties, and three‐dimensional structure, are discussed. Finally, we briefly conclude with the state of the current research on highkpolymer composites and present our perspectives on future challenges in the development of new highkpolymer composites.
MagC is a NplC/P60‐like member of the α‐2‐macroglobulin Mag complex of Pseudomonas aeruginosa that interacts with peptidoglycan
Authors: Zouhir Samira , Contreras‐Martel Carlos , Maragno Trindade Daniel , Attrée Ina , Dessen Andréa , Macheboeuf Pauline 
Published: June 2021

Bacterial α‐2 macroglobulins (A2Ms) structurally resemble the large spectrum protease inhibitors of the eukaryotic immune system. In Pseudomonas aeruginosa, MagD acts as an A2M and is expressed within a six‐gene operon encoding the MagA‐F proteins. In this work, we employ isothermal calorimetry (ITC), analytical ultracentrifugation (AUC), and X‐ray crystallography to investigate the function of MagC and show that MagC associates with the macroglobulin complex and with the peptidoglycan (PG). However, the catalytic residues of MagC display an inactive conformation that could suggest that it binds to PG but does not degrade it. We hypothesize that MagC could serve as an anchor between the MagD macroglobulin and the PG and could provide stabilization and/or regulation for the entire complex.
Pectic Galactan Polysaccharide‐Based Gene Delivery System for Targeting Neuroinflammation
Authors: Buaron Nitsa , Mangraviti Antonella , Volpin Francesco , Liu Ann , Pedone Mariangela , Sankey Eric , Aranovich Dina , Adar Itay , Rodriguez Fausto J. , Nyska Abraham , Goldbart Riki , Traitel Tamar , Brem Henry , Tyler Betty , Kost Joseph 
Published: June 2021

AbstractTreating neuroinflammation‐related injuries and disorders through manipulation of neuroinflammation functions is being heralded as a new therapeutic strategy. In this study, a novel pectic galactan (PG) polysaccharide based gene therapy approach is developed for targeting reactive gliosis in neuroinflammation. Galectin‐3 (Gal‐3) is a cell protein with a high affinity to β‐galactoside sugars and is highly expressed in reactive gliosis. Since PG carries galactans, it can target reactive gliosis via specific carbohydrate interaction between galactan and Gal‐3 on the cell membrane, and therefore can be utilized as a carrier for delivering genes to these cells. The carrier is synthesized by modifying quaternary ammonium groups on the PG. The resulting quaternized PG (QPG) is found to form complexes with plasmid DNA with a mean diameter of 100 nm and have the characteristics required for targeted gene therapy. The complexes efficiently condense large amounts of plasmid per particle and successfully bind to Gal‐3. The in vivo study shows that the complexes are biocompatible and safe for administration and can selectively transfect reactive glial cells of an induced cortical lesion. The results confirm that this PG‐based delivery system is a promising platform for targeting Gal‐3 overexpressing neuroinflammation cells for treating neuroinflammation‐related injuries and neurodegenerative diseases.