bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perancangan Aplikasi Sistem Informasi Layanan Laundry Berbasis Website di Laundry Happy Clean
Authors: Baehaki Riki , Azukruf Robby , Haryono Wasis 
Published: December 2024

Tujuan dari penelitian ini adalah untuk menciptakan suatu sistem informasi yang memudahkan operasional perusahaan saat ini dengan mengkomputerisasi pencatatan dan pengolahan transaksi dan persediaan. Sebelum penulis menelusuri, perusahaan ini terbebani dengan layanan laundry karena jumlah klien yang berlebihan sehingga mengakibatkan pencatatan pesanan tidak teratur, terkadang pencatatan data mengenai ketersediaan tabung dan stok laundry tidak akurat, serta kesalahan biaya. perhitungan biaya laundry yang harus dibayar klien. Teknik deskriptif yang digunakan dalam penelitian ini, data yang penulis peroleh berasal dari observasi langsung terhadap pengelola Happy Clean Laundry serta wawancara dengan narasumber terkait. Penulis memanfaatkan diagram kasus dan sumber lain untuk membantu penelitian ini. Temuan penelitian ini diharapkan dapat memberikan suatu sistem informasi yang memungkinkan pencatatan pendapatan, biaya, dan ketersediaan stok bahan baku laundry secara efisien, cepat, dan efektif. Penelitian ini menggunakan metode deskriptif melalui observasi langsung dan wawancara untuk memahami kebutuhan sistem informasi.

The objective of this research is to create an information system that will help the company's current operations by capturing and processing transactions and computerizing the stock of items. Prior to the authors' investigation, the company was overburdened with laundry services due to an excessive number of users, which resulted in disorganized order records and occasionally inaccurate data records on Happy Clean. Additionally, there were errors in determining the amount of laundry that the customer was responsible for paying. The descriptive approach is employed in this study, and the author gathered the data by directly seeing the laundry happy clean and interviewing the relevant informant. Case diagrams and other tools are used by the author to assist this research. It is anticipated that the findings of this study will provide an information system that will enable the efficient, rapid, and effective recording of income, costs, and the stock of laundry basic materials.
A Comprehensive Literature Review of Histopathology of Squamous Cell Carcinoma
Authors: Wahyu Agus Prastyo  , Artha Investari Nugraheni  
Published: December 2024

Background: The literature on the histopathology of squamous cell carcinoma (SCC), particularly cutaneous squamous cell carcinoma (cSCC), has evolved significantly over the past decade, revealing a complex interplay of histopathologic features, molecular markers, and clinical outcomes. Literature Review: The work by (K. El-Mofty, 2014) explores histopathologic risk factors associated with oral and oropharyngeal SCC variants, particularly those related to HPV. The identification of distinct morphological characteristics shared among keratinizing neoplasms is essential for accurate diagnosis and treatment planning. The article highlights the unique behaviors of HPV-related variants, which may exhibit either favorable prognoses or aggressive metastatic potential, thus necessitating careful evaluation. The role of immunohistochemical markers in the diagnosis and staging of cSCC is further elaborated by (Bălășescu et al., 2022), who identify key characteristics that predict disease progression. Their findings suggest that immunohistochemical markers can enhance diagnostic accuracy, particularly in poorly differentiated cases, thereby informing treatment strategies. Finally, (Gabriel Cocuz et al., 2022) provide a scientometric analysis of current research directions, highlighting the sustained interest in histopathology and immunohistochemistry of cSCC. Their work suggests an ongoing recognition of the importance of personalized diagnostics and targeted therapies to improve patient outcomes. Conclusion: In conclusion, the reviewed literature underscores the complexity of cSCC histopathology and the critical need for accurate diagnosis and staging. The integration of histopathological features with molecular markers and the continual evolution of diagnostic techniques are essential for refining our understanding of SCC behavior and enhancing treatment efficacy. Ongoing research is necessary to address existing challenges and optimize patient management strategies.
Effects of altered climates on American ginseng population dynamics
Authors: Souther Sara , McGraw James B. , Souther John D. , Waller Donald M. 
Published: September 2021

AbstractAs climates change, species with locally adapted populations may be particularly vulnerable as specialization narrows the range of conditions under which populations can persist. Populations adapted to local climate as well as other site‐specific characteristics like soils present challenges for inferring how changing climates affect fitness, as climatic and nonclimatic variables that constitute local conditions decouple. We conducted two transplant experiments involving American ginseng to test how climatic conditions affect performance while controlling for effects of other site characteristics. We first out‐planted populations from differing elevations to gardens arrayed along an elevation/climate gradient. We also grew maternal plants under temperatures corresponding to home‐site and future conditions (16.4–22.4°C), transplanting resultant progeny to two home‐sites at different elevations (400 m, 800 m). Source populations responded idiosyncratically to elevation reflecting how nonclimatic site characteristics strongly affected plant fitness. Germination rates declined for seeds from maternal plants exposed to warmer temperatures, which compounded with diminished seed production of maternal plants, suggested that population growth may decline rapidly as warm years become hotter and more frequent. Controlling for maternal temperature effects provided evidence that plants are adapted to home‐site conditions, both climatic and nonclimatic, with population growth rates for out‐planted populations ranging from below population replacement levels (λ = 0.58) to well above (λ = 1.33). Evidence of local adaptation to climatic and nonclimatic environmental components, in combination with negative fitness impacts of warming climates on offspring via maternal effects, suggests that changing climate may imperil ginseng and other similar understory species.
Sex differences of parental phubbing on online hostility among adolescents: A moderated mediation model
Authors: Wang Hongxia , Zhou Li , Geng Jingyu , Lei Li 
Published: September 2021

AbstractTo explore the relationship between parental phubbing (PP) and adolescent online hostility and its' psychological mechanism, 689 Chinese adolescents were recruited to complete a paper‐and‐pencil questionnaire. We took cyber flaming (CF) as an overall category for hostile online communication to investigate the relationship between PP and CF and the mediating role of perspective‐taking (PT) in this relationship and examined whether there is a sex difference in this process. After controlling the average daily online time, the results showed that PP predicted adolescent CF positively. The relationship between PP and CF was partially mediated by PT. The effect of PP on PT was moderated by sex, with the result being significant only for boys. Related findings and future directions were discussed.
Soft X‐Ray Stimulated Lanthanide@MOF Nanoprobe for Amplifying Deep Tissue Synergistic Photodynamic and Antitumor Immunotherapy
Authors: Zhao Xiaoting , Li Youbin , Du Linman , Deng Zhiming , Jiang Mingyang , Zeng Songjun 
Published: September 2021

AbstractCombining photodynamic therapy (PDT) and immunotherapy has shown profound impact for synergistic treatment of malignant tumors. However, the shallow penetration depth of the traditional visible light activated PDT, immunosuppressive tumor microenvironment (TME), and poor immunogenicity of deep‐seated solid tumors have significantly impeded the therapeutic efficiency. Herein, a soft X‐ray activated nanoprobe is rationally engineered via integrating porphyrin Zr‐based metal–organic framework with lanthanide NaYF4:Gd,Tb@NaYF4 scintillator nanoparticles (SNPs) by a new in situ growth strategy for synergistic PDT and immunotherapy of tumor. The nanoprobe possesses remarkably enhanced reactive oxygen species (ROS) generation triggered by soft X‐ray via further covalently grafting rose bengal on the nanoprobe, even at tissue depths of 3 cm. Moreover, the soft X‐ray induced ROS can act as potential immunogenic cell death (ICD) trigger, subsequently leading to the activation of the adaptive antitumor immune‐response. Significantly, the boosted ROS generation can further modulate the immunosuppressive TME. This work provides new strategy of designing antitumor nanoprobes for soft X‐ray triggered deep‐tissue PDT and immune response, breaking the depth barriers suffered by the traditional photoactivated PDT or ICD using visible and near infrared light.
β‐Catenin Limits Osteogenesis on Regenerative Materials in a Stiffness‐Dependent Manner
Authors: Zhou Qi , Ren Xiaoyan , Oberoi Michelle K. , Bedar Meiwand , Caprini Rachel M. , Dewey Marley J. , Kolliopoulos Vasiliki , Yamaguchi Dean T. , Harley Brendan A. C. , Lee Justine C. 
Published: September 2021

AbstractTargeted refinement of regenerative materials requires mechanistic understanding of cell–material interactions. The nanoparticulate mineralized collagen glycosaminoglycan (MC‐GAG) scaffold is shown to promote skull regeneration in vivo without additive exogenous growth factors or progenitor cells, suggesting potential for clinical translation. This work evaluates modulation of MC‐GAG stiffness on canonical Wnt (cWnt) signaling. Primary human bone marrow‐derived mesenchymal stem cells (hMSCs) are differentiated on two MC‐GAG scaffolds (noncrosslinked, NX‐MC, 0.3 kPa vs conventionally crosslinked, MC, 3.9 kPa). hMSCs increase expression of activatedβ‐catenin, the major cWnt intracellular mediator, and the mechanosensitive YAP protein with near complete subcellular colocalization on stiffer MC scaffolds. Overall Wnt pathway inhibition reduces activatedβ‐catenin and osteogenic differentiation, while elevating BMP4 and phosphorylated Smad1/5 (p‐Smad1/5) expression on MC, but not NX‐MC. Unlike Wnt pathway downregulation, isolated canonical Wnt inhibition withβ‐catenin knockdown increases osteogenic differentiation and mineralization specifically on the stiffer MC.β‐catenin knockdown also increases p‐Smad1/5, Runx2, and BMP4 expression only on the stiffer MC material. Thus, while stiffness‐induced activation of the Wnt and mechanotransduction pathways promotes osteogenesis on MC‐GAG, activatedβ‐catenin is a limiting agent and may serve as a useful target or readout for optimal modulation of stiffness in skeletal regenerative materials.
A Review of the Terahertz Conductivity and Photoconductivity of Carbon Nanotubes and Heteronanotubes
Authors: Burdanova Maria G. , Tsapenko Alexey P. , Kharlamova Marianna V. , Kauppinen Esko I. , Gorshunov Boris P. , Kono Junichiro , Lloyd‐Hughes James 
Published: September 2021

Terahertz (THz) spectroscopy is an ideal non‐contact and non‐destructive technique that probes the electrical conductivity of nanomaterials. This review presents the current status of research in the THz properties of quasi‐1D materials, such as nanotubes (NTs) and NT heterostructures. Detailed descriptions of THz experimental methods (THz time‐domain spectroscopy, optical pump‐THz probe spectroscopy) and conductivity extraction methods are presented along with the physical models (Drude, plasmon, effective medium theories, etc.) supporting them. Optoelectronic applications, such as optical modulators, switches, and shielding devices, are discussed and illustrate a bright future for these materials.
Noncovalent CH–π and π–π Interactions in Phosphoramidite Palladium(II) Complexes with Strong Conformational Preference
Authors: Žabka Matej , Naviri Lavakumar , Gschwind Ruth M. 
Published: September 2021

AbstractThe weak noncovalent interactions and flexibility of ligands play a key role in enantioselective metal‐catalyzed reactions. In transition metal complexes and their catalytic applications, the experimental assessment and the design of key interactions is as difficult as the prediction of the enantioselectivities, especially for flexible, privileged ligands such as chiral phosphoramidites. Therefore, the interligand interactions in cis‐PdIIL2Cl2 phosphoramidite complexes were investigated by NMR spectroscopy and computations. We were able to induce a strong conformational preference by breaking the symmetry of the C2‐symmetric side chain of one of the ligands, and shift the equilibrium between hetero‐ and homocomplexes towards heterocomplexes because of interligand interactions in the cis‐complexes. The modulation of aryl substituents was exploited, along with the solvent effect. The combined CH–π and π–π interactions reveal design patterns for binding and folding of chiral ligands and catalysts.
Heterojunction‐Based Electron Donators to Stabilize and Activate Ultrafine Pt Nanoparticles for Efficient Hydrogen Atom Dissociation and Gas Evolution
Authors: Sun Lu‐Han , Li Qi‐Yuan , Zhang Shi‐Nan , Xu Dong , Xue Zhong‐Hua , Su Hui , Lin Xiu , Zhai Guang‐Yao , Gao Peng , Hirano Shin‐Ichi , Chen Jie‐Sheng , Li Xin‐Hao 
Published: September 2021

AbstractPlatinum (Pt) is the most effective bench‐marked catalyst for producing renewable and clean hydrogen energy by electrochemical water splitting. There is demand for high HER catalytic activity to achieve efficient utilization and minimize the loading of Pt in catalysts. In this work, we significantly boost the HER mass activity of Pt nanoparticles in Ptx/Co to 8.3 times higher than that of commercial Pt/C by using Co/NC heterojunctions as a heterogeneous version of electron donors. The highly coupled interfaces between Co/NC and Pt metal enrich the electron density of Pt nanoparticles to facilitate the adsorption of H+, the dissociation of Pt−H bonds and H2 release, giving the lowest HER overpotential of 6.9 mV vs. RHE at 10 mA cm−2 in acid among reported HER electrocatalysts. Given the easy scale‐up synthesis due to the stabilization of ultrafine Pt nanoparticles by Co/NC solid ligands, Ptx/Co can even be a promising substitute for commercial Pt/C for practical applications.
Towards High‐Performance Resistive Switching Behavior through Embedding a D‐A System into 2D Imine‐Linked Covalent Organic Frameworks
Authors: Li Chenyu , Li Dong , Zhang Weifeng , Li Hao , Yu Gui 
Published: September 2021

AbstractDeveloping new materials for the fabrication of resistive random‐access memory is of great significance in this period of big data. Herein, we present a novel design strategy of embedding donor (D) and acceptor (A) fragments into imine‐linked frameworks to construct resistive switching covalent organic frameworks (COFs) for high‐performance memristors. Two D‐A‐type two‐dimensional COFs,COF‐BT‐TTandCOF‐TT‐TVT, were designed and synthesized using a conventional solvothermal approach, and high‐quality thin films of these materials deposited on ITO substrate exhibited great potential as an active layer for memristors. Rewritable memristors based on 100 nm thickCOF‐TT‐BTandCOF‐TT‐TVTfilms showed a high ON/OFF current ratio (ca. 105and 104) and low driving voltage (1.30 and 1.60 V). The cycle period and retention time forCOF‐TT‐BT‐based rewritable devices were as high as 319 cycles and 3.3×104 s at a constant voltage of 0.1 V (160 cycles and 1.2×104 s for theCOF‐TT‐TVTmemristor).
Selective1HαNMR Methods Reveal Functionally Relevant Prolinecis/transIsomers in Intrinsically Disordered Proteins: Characterization of Minor Forms, Effects of Phosphorylation, and Occurrence in Proteome
Authors: Sebák Fanni , Ecsédi Péter , Bermel Wolfgang , Luy Burkhard , Nyitray László , Bodor Andrea 
Published: September 2021

AbstractIt is important to identify prolinecis/transisomers that appear in several regulatory mechanisms of proteins, and to characterize minor species that are present due to the conformational heterogeneity in intrinsically disordered proteins (IDPs). To obtain residue level information on these mobile systems we introduce two1Hα‐detected, proline selective, real‐time homodecoupled NMR experiments and analyze the proline abundant transactivation domain of p53. The measurements are sensitive enough to identify minor conformers present in 4–15 % amounts; moreover, we show the consequences of CK2 phosphorylation on thecis/trans‐proline equilibrium. Using our results and available literature data we perform a statistical analysis on how the amino acid type effects thecis/trans‐proline distribution. The methods are applicable under physiological conditions, they can contribute to find key proline isomers in proteins, and statistical analysis results may help in amino acid sequence optimization for biotechnological purposes.
Repurposing π Electrophilic Cyclization/Dealkylation for Group Transfer
Authors: Kaplan Joseph A. , Issaian Adena , Stang Martin , Gorial David , Blum Suzanne A. 
Published: September 2021

AbstractA metal‐free regio‐ and stereocontrolled group‐transfer route toward the synthesis of trisubstituted alkenes is described. In this route, an electrophilic heterocyclization is followed by ring‐opening group transfer. Specifically, a thioboration reaction transforms readily available alkynyl sulfide precursors into alkenyl boronates and alkenyl sulfides with defined regio‐ and stereochemistry in one synthetic step using commercially available B‐chlorocatecholborane (ClBcat). Mechanistic studies identified the likely pathway as proceeding through zwitterionic rather than haloborated intermediates. The regio‐ and stereochemistry set in the initial cyclization step is preserved in the final acyclic alkene product, producing alkenes with up to four modifiable substituents with predictable regio‐ and stereochemistry. Downstream functionalization reactions showcase the versatility of the substitutions of the resulting alkenes. The mechanistic concept maps onto future reaction designs, given the abundance of known electrophiles and nucleophiles for electrophilic heterocyclization/dealkylation sequences.
Taxonomic diversity and distribution of the genus Proterorhinus (Teleostei: Gobiidae) in the Caucasus biodiversity hotspot with conservation implications
Authors: Zarei Fatah , Esmaeili Hamid Reza , Schliewen Ulrich K. , Abbasi Keyvan 
Published: September 2021

Abstract

The magnitude of biodiversity in the Caucasus biodiversity hotspot remains largely unknown, because species diversity is usually assessed based on morphology. One ecologically important fish group with cryptic diversity is the tubenose goby members of the genus Proterorhinus, for which recent studies have shown that species assignments are difficult.
Using mitochondrial COI data (652 bp) from 59 widespread localities, a phylogenetic and phylogeographical framework is applied to assess the species‐level status of different Caucasian populations of Proterorhinus, previously classified as Proterorhinus nasalis. We infer how post‐Miocene evolution of the Caspian basin may have shaped the present diversity and distribution of P. nasalis.
The results suggest that Proterorhinus diversity in the Caucasus has been underestimated: (i) specimens from Azerbaijan and the Samur River delta on the Caspian shore share haplotypes with Proterorhinus semipellucidus; (ii) specimens from the Black Sea shore at Kodori Bay, the Kintrishi, and Mcnishta rivers of Georgia share haplotypes with two lineages of Proterorhinus semilunaris; and (iii) south Caspian specimens from the Iranian sites studied belong to P. nasalis.
A pattern of low haplotype and nucleotide diversity was observed in P. nasalis, suggesting a founder event by a single or a few mitochondrial haplotypes following the isolation between the Black and Caspian seas in the early Pliocene or a demographic bottleneck during salinity and lake‐level changes in the Babadjanian, Balakhanian and Tyurkyanian stages.
Integrative use of genetic assessments for monitoring Caucasian biodiversity will help to understand the extent of biodiversity and reliably assess threat status for critical species. Considering the species' narrow distribution range, small population size and low genetic variability, P. nasalis may merit an upgrade from Least Concern to an IUCN Red List Threatened Category (i.e. Vulnerable, Endangered or Critically Endangered).
Design and Synthesis Strategies: 2D Materials for Electromagnetic Shielding/Absorbing
Authors: Zhang Jie , Zhang Jianchao , Shuai Xiaofeng , Zhao Ruihua , Guo Tianyu , Li Kexun , Wang Donghong , Ma Chen , Li Jinping , Du Jianping 
Published: September 2021

AbstractTwo‐dimensional (2D) materials possess special physical and chemical properties. They have been proved to have potential application advantage in the microwave absorption (MA) and electromagnetic interference (EMI) shielding. Particularly, they exhibit positive shielding and absorbing response to EMI. Here, the research progress of preparation, electromagnetic performance and microwave shielding/absorbing mechanisms of 2D composite materials are introduced. Effective preparation routes including introducing heteroatoms, constructing unique structures and 2D composite materials are described. Furthermore, the application prospects and challenges for the development of novel EMI materials are expatiated.
Study of anti‐windup pi controllers with different coupling–decoupling tuning gains in motor speed
Authors: Chiah Thong Ling , Hoo Choon Lih , Chung Edwin Chin Yau 
Published: September 2021

AbstractProportional‐integral (PI) controller is still a widely used closed‐loop controller in industrial applications due to its simplicity. PI controllers experience difficulty in having both non‐overshoot with short rise time. Such unfavorable response is due to its coupled tuning‐gains and the integral windup, which eventually leads to system instability. Various anti‐windup techniques have been proposed. However, similar to the conventional PI controllers, most of these techniques have coupled proportional and integral tuning gains that affect one another. The controllers contain adaptive switching between the conventional and its designated integral control depending on the saturation state. This paper proposes a robust non‐switching anti‐windup PI controller with semi‐decoupling tuning gain. Speed control simulation and experimental testing are conducted to investigate the impact of the various tuning gain dependency. The proposed controller shows a fast response with no overshoot as compared to the conventional and other non‐switching anti‐windup PI controllers with coupling and decoupling tuning gain at certain loading conditions.