bluuebunny/crossref_metadata_2025_split huggingface dataset:
Percutaneous Transhepatic Biliary Drainage as a Viable Alternative to Failed Endoscopic Retrograde Cholangiopancreatography in Hepatobiliary Disorders: A Retrospective Analysis
Authors: Asadullah Muhammad , Naz Nasreen , Sattar Amjad , Al Qamari Nauman , Ahmed Parvez , Ahmed Zahoor 
Published: December 2024

The conventional second-line treatment for failed ERCP was Percutaneous Transhepatic Biliary Drainage (PTBD). Because of its high level of success and accessibility, PTBD has evolved into a well-established rescue therapy. Objective: To assess the procedural outcomes of PTBD following a failed ERCP in patients with hepatobiliary disorders. Additionally, it was focused on finding the significant factors that impact PTBD outcomes. Methods: A retrospective descriptive analysis was performed on 128 individuals at Dow Hospital Ojha Campus Karachi, who received PTBD following a failed ERCP. Between January 2023 and March 2024, we evaluated the clinical success rate, post-PTBD complications, and mortality. Results: The mean age of the patients was 65.9+/-11.7 years, and 76 (59.4%) patients were female. The clinical success rate was 77.3%, and complications after PTBD were 20(15.6%). A prolonged hospital stay was reported in 29 (22.7%) patients, and 13 (10.2%) patients died within 30 days. Younger age, etiology, and type of PTBD had a significant association with clinical success (P<0.05). Older age, female patients, and malignant etiology had a higher complication rate and mortality (P<0.05). Conclusions: PTBD provides a safe, effective, and viable alternative approach for patients with hepatobiliary disorders. It has a low rate of complications, a high rate of procedural success, and a low risk of mortality after a failed ERCP. Adverse events were more common in patients with a malignant etiology, older age, and female gender.
Nervous Discrepancy of Spinal Cord Schwannoma Causing Posterior Neck Swelling
Authors: Saeed Soobia , Ghani Rubina , Shahid Zeelaf , Naseeb Uzma , Khan Ubaid Ahmed 
Published: December 2024

A 20-year-old man with chronic cervical pain has been diagnosed with cervical spinal schwannomas, a benign tumor in the posterior neck. Objective: To analyze the spinal cord schwannomas causing posterior neck swelling. Methods: In the first step, the vertebral canal portion of the tumor at C4 was removed entirely with a midline approach to the posterior spinal column. The patient underwent a laminectomy procedure in the second surgical session to remove tumors at C2 and C3, resulting in no neurological issues upon discharge from the hospital. Results: Schwannomas was diagnosed histopathologically. In patients with cervical intra-spinal schwannomas that have spread to the extra vertebral paravertebral neck region, the first goal of surgery is to treat the neurological deficits. Conclusions: It was concluded that the posterior midline and laminectomy approach approaches are combined in the same session or at different times in the surgical strategy.
Correlation of Developmental Dysplasia of Hip in Newborns with Mode of Presentation on Graf Method Ultrasound
Authors: Marvi Nasim , Khokhar Samia Khalid , Alam Omar , Qamar Aisha , Mahar Yasmeen , Fatimee Sarwath 
Published: December 2024

Developmental dysplasia of hip (DDH) affects 1.5-20/1000 live births. Early detection and treatment have spared many patients from crippling. The dislocation of the hip is always postnatal. Defects in hip occur because of the flexibility of the joint capsule at birth, underdeveloped hip acetabulum and immature femur head. Objective: To correlate incidence of developmental dysplasia of hip in newborns with modes of presentation at birth (vertex, breech and transverse) using Graf method ultrasound. Methods: The six-month analytical cross-sectional study was conducted after ethical approval and informed parental consent. A total of 115 healthy newborns below 28 days age were inducted in the study. The study excluded neuromuscular disease, neural tube defects and genetic anomaly cases. The bilateral hip angles were measured on ultrasound, categorized and recorded. Modes of presentation (vertex, breech and transverse) and physical exam findings were included. Results: Hip angles were measured in 115 newborns. The vertex presentation was the most common; 96 (83.48%). Infants with vertex presentation had the significantly smaller frequency of dysplasia (p<0.001). Breech presentation had significantly high incidence of hip dysplasia (p<0.001). Bilateral pathological immature hip (2a-) and centered unstable (2c) hip dysplasia types were most common in all groups. Severe dysplasia types D and 4 were seen in the vertex and breech groups. Conclusions: Developmental dysplasia of hip occurs with vertex, transverse and breech presentation postnatally. The most frequent variants are the immature pathological and centered unstable hips. The severe forms of dysplasia occur in vertex and breech presentations
Use of YouTube for Mastery of Clinical Skills in Dental Education
Authors: Qureshi Muhammad Ammar , Khalid Saria , Rana Azeem , Munawar Huzaifa , Malik Khizar Ansar 
Published: December 2024

The increasing integration of digital platforms has transformed the way clinical skills are taught in dental education. YouTube has emerged as a prominent resource, offering an array of instructional videos that can supplement traditional learning. However, the extent to which dental students in Pakistan utilize this platform for clinical skill acquisition remains underexplored, highlighting a significant gap in the existing literature. Objectives: To evaluate the utilization and effectiveness of YouTube as a learning tool for clinical skills among dental students and house officers. Methods: A cross-sectional survey was conducted with 150 dental students and house officers at Combined Military Hospitals, Lahore Medical College, Institute of Dentistry. House officers from other medical professions were excluded. The sample size of 150 was calculated through the M Calculator. Participants completed a 19-item questionnaire. The collected data were analyzed using SPSS version 26.0. For the data analysis, descriptive tests, frequencies, chi-square and the Kruskal Wallis tests were employed. Results: Most students (87.3 %) solely depended on internationally produced videos. 26.7% of the participants used the platform for educational purposes. Only 44% of the participants used YouTube as a supplement to learn clinical procedures. 47.3% reported watching YouTube videos before their first attempt at a procedure. Conclusions: It was concluded that YouTube is a valuable source of learning and presents the necessity of incorporating technology-enhanced tools, such as YouTube, into dental schools.
Early Blood Pressure Changes in Neonatal Sepsis and the Risk of Mortality
Authors: Ali Kamran , Haque Tayyaba , Bahalkani Ubedullah , Bhanbhro Bakhtiar Ahmed , Bharo Mumtaz Ali , Ali Faiza Kamran 
Published: December 2024

Neonatal sepsis is an increasingly common cause of mortality and morbidity in newborns, with hemodynamic abnormalities impacting prognosis. Objectives: To evaluate the relationship between blood pressure levels and in-hospital mortality rate in newborns with sepsis. Methods: The comparative cross-sectional study was conducted for six months from August 2023 to January 2024 at the Department in the Neonatal Intensive Care Unit of Khairpur Medical College to Khairpur Mir’s Medical College Teaching Hospital. The total number of participants was n=300 (n=150 participants per group). Blood pressure was monitored at three different periods: 0-24 hours, 24-48 hours, and 48-72 hours. Data were analyzed using t-test independent, chi-square and multivariable logistic regression to assess the association between blood pressure parameters and in-hospital mortality. Results: Our findings indicated that lower systolic, diastolic, and mean blood pressures at all measured time points were closely linked to higher mortality rates in newborns. At 72 hours, culture-positive infants had a median systolic blood pressure of 64 mmHg, while those with clinical signs had a median of 70 mmHg (p=0.008). Each unit's reduction in blood pressure corresponded to a significant increase in the risk of death. Conclusions: It was concluded that neonates with sepsis had lower mean, diastolic, and systolic blood pressures have a higher mortality rate in hospitals which shows that sepsis with positive culture has a higher risk of severe hemodynamic instability when compared to sepsis with clinical signs.
Immuno-Histochemical Analysis of PDGFRβ in OSCC: Clinical Significance and Prospects for Targeted Therapy
Authors: Rabbani Sarah , Rehman Aman ur , Anjum Rabia , Khan Nauman Rauf , Chudhary Saima 
Published: December 2024

The most prominent and key cells in cancer development are fibroblasts, known as cancer-associated fibroblasts. Limited data available on Head and Neck Cancer showed the presence of platelet-derived growth factor receptor beta as the most prevalent marker. Furthermore, therapies can be targeted against this receptor for the treatment of cancer. Objectives: To evaluate the expression of Platelet-derived growth factor receptor beta as a specific marker of cancer-associated fibroblasts in different grades of oral squamous cell carcinoma through immunohistochemistry. Methods: This descriptive study included 51 cases of squamous cell carcinoma of the head and neck region. Platelet-derived growth factor receptor beta expression was assessed based on the extent and intensity of immune-labelling in a tumor. SPSS was used to determine the association between the grade of tumor and Platelet-derived growth factor receptor beta expression. Results: Mean age was found as 53.65 + 17.15 years and there were 30 (58.8%) male and 21 (41.2%) female. The most commonly affected sites were glottis and supra-glottis areas accounting for 18.9% of total cases followed by the tongue which accounts for 13.2% of cases. The majority of the patients 34 (66.7%) patients had an intermediate grade of squamous cell carcinoma. In most cases, the degree of staining was strongest, with intermediate-grade tumors exhibiting the highest platelet-derived growth factor receptor beta staining. Conclusions: It was concluded that platelet-derived growth factor receptor beta emerges as a promising tumor marker in head and
Types of Inherited Hemoglobin Disorders among the Patients Attending a Tertiary Care Hospital
Authors: Anwar Rehan , Arzoo Kamran , Riaz Adnan , Ali Riasat , Saghir Sumera , Habib Bilal 
Published: December 2024

The genetic conditions known as hemoglobinopathies, which include thalassemia impact the synthesis and structure of Hemoglobin, the red blood cell protein that carries oxygen. Objectives: To investigate the prevalence of different types of thalassemia associated with age, gender and Hematological parameters. Methods: The total number of participants was n=139. The cross-sectional study was conducted at Rai Medical College Sargodha. The study was conducted for six months, from July 2023 to Dec 2023. Biochemical parameters investigated such as Hemoglobin, mean corpuscular hemoglobin MCH, reticulocyte and ferritin were done in the Hematology lab. Collected data were analyzed by SPSS version 25.0. Results: The gender distribution among the participants included male 50.3% and female 49.6%. The mean age of the patients was approximately 34.8 years. This study of 139 participants found Hb-E Beta Thalassemia (25.4%) to be the most common type, especially among those with a history of cousin marriage. Severe forms like Hb-E Beta Thalassemia and Beta Thalassemia Major had low hemoglobin and MCH levels, indicating severe anemia, while milder forms showed near-normal levels. In mean corpuscular Hemoglobin E Beta Thalassemia (29.7 ± 4.1), p=0.001, mean corpuscular Hemoglobin A levels are considerably lower than Beta Thalassemia Trait. There was no association with age and gender, p>0.005. Conclusions: It was concluded that our investigation offered important insights into the biochemical profiles linked to various thalassemia types, even though it did not identify any appreciable variations in thalassemia prevalence by age or gender.
Ankle-Brachial Index as a Predictor of Peripheral Arterial Disease in Newly Diagnosed Hypertensive Patients
Authors: Pervez Safdar Ali , Channa Munir Ahmed , Kumar Mahesh , Phulpoto Abdul Hayee , Memon Abdul Qayoom , Aziz Asif 
Published: December 2024

Hypertension was a major risk factor for cardiovascular disorder including Peripheral Arterial Disease (PAD). Objective: To evaluate the risk of Peripheral Arterial Disease (PAD) in newly diagnosed hypertensive patients using Ankle-Brachial Index (ABI) measurements and to determine its potential role as a predictor of cardiovascular risks in this population. Methods: The study was an observational, cross-sectional study. This study was conducted in Khairpur Medical College Civil Hospital Khairpur Mirs. The duration of this study was six months, from November 2023 to April 2024This study include n= 246 newly diagnosed hypertension. Three levels of ABI had been identified through determining the ABI in both legs: low ABI (<0.9), normal ABI (0.9-1.4), and high ABI (>1.4). Student’s t-test. Pearson correlation test have been utilized when assessing the significance of the association between ABI levels and blood pressure values. Results: ABI was normal in 60% of the 246 participants, low in 20% and high in 20% of them. In comparison to those who had normal and high ABI, participants who had low ABI showed considerably higher SBP in both lower limbs (p < 0.001). Furthermore, there was additionally a significant distinction (p < 0.001) in the SBP and DBP among people who had high ABI. Participants with average ABI had higher SBP in their right upper limb than those who suffered from elevated ABI (p < 0.001). Conclusion: This study showed that in individuals who have recently identified high blood pressure, there was a significant relationship among ABI levels and arterial pressure levels.
Association of Bacterial Vaginosis with Preterm Labour in Pregnant Women
Authors: Qamar Ayesha , Aziz Moizza , Riffat Najia , Tehseen Saema , Yaqoob Shagufta , Zaheer Fareeha 
Published: December 2024

Bacterial Vaginosis (BV) was a common vaginal infection associated with adverse pregnancy outcomes, including premature birth. Objective: To evaluate the association between the BV and the risk of preterm Labor in pregnant women and to assess whether BV prevalence differs based on obstetric history, including parity and prior delivery outcomes. Methods: This case-control study was conducted in the Obstetrics and Gynecology Department at PAF Hospital Mushaf, Sargodha, from July 2022 to January 2023. A total of 130 participants were included in the study. BV was diagnosed using laboratory and diagnostic methods. Participants were enrolled using non-probability consecutive sampling. Data were analyzed using SPSS version 21.0. Chi-square tests and odds ratios were employed to assess the association between bacterial vaginosis and variables such as age, gravida, and history of preterm delivery, with a p-value ≤ 0.05 considered statistically significant. Results: The mean age of the participants was 25.32±6.8 years. Parity also had a notable impact, with multiparous women showing a significantly higher prevalence of BV (46.2%) compared to controls (18.2%), with an OR of 3.86; P=0.006. However, the difference among primiparous women was insignificant (P=0.477, OR=1.56). Women with no prior delivery history had a higher BV prevalence in the case group, 41.5%, compared to the control group, 20.0%, with an OR of 2.83; P=0.130. Conclusions: Bacterial vaginosis was significantly associated with older maternal age and multiparity, but no strong correlation was found with previous preterm delivery. Timely diagnosis and management of BV may help reduce the risk of preterm labor.
PENARAPAN PENGURANGAN HUKUMAN TINDAK PIDANA BERDASARKAN RESTORATIF JUSTICE MENURUT PERMA NOMOR 1 TAHUN 2024
Authors: Agus Sugiyatmo  , Ermania Widjajanti  
Published: December 2024

Restorative Justice bertujuan untuk mengubah paradigma penegakan hukum yang lebih berfokus pada pemulihan daripada hukuman. Restorative dalam pidana adalah upaya terakhir (ultimum remedium). Restorative Justice sebenarnya sudah diterapkan pada jaman nenek moyang kita yang orang timur dengan penyelesaikan masalah dengan musyawarah mufakat. Perkembangan Restorative justice di Indonesia secara formal muncul dalam sistem hukum Indonesia melalui Undang-Undang Nomor 11 Tahun 2012 tentang Sistem Peradilan Pidana Anak (UU SPPA), yang menekankan pada pengalihan proses peradilan pidana ke proses diluar peradilan pidana (diversi) untuk anak yang berhadapan dengan hukum. Lalu berkembang berbagai peraturan dan kebijakan di tahap penyidikan di Kepolisian dengan Peraturan Polri Nomor 8 Tahun, tahap penuntutan di Kejaksaan dengan Peraturan Kejaksaan Nomor 15 Tahun 2020, dan ditahap Pengadilan di Mahkamah Agung dengan Peraturan Mahkamah Agung Nomor 1 Tahun 2024. Masing – masing peraturan internal lembaga tersebut dengan UU Nomor 1 Tahun 2023 (KUHP Baru) sebagai aturan yang lebih tinggi, dengan harapan adanya pemetaan peraturan – peraturan tersebut dapat diketahui perlunya penyesuaian atau pencabutan peraturan tersebut dengan adanya KUHP Baru. Ke depannya hasil asesmen tersebut dapat berkontribusi sebagai masukan dalam penyusunan revisi Undang – Undang Nomor 8 Tahun 1981 tentang Hukum Acara Pidana (KUHAP).
Digital production and new media convergence publishing practice of scientific and technological periodicals based on XML integration: The case of Acta Scientiae Circumstantiae
Authors: Yang Guihua , Bu Qingjie , Wang Hu , Li Yonghuan 
Published: December 2024

Background: This study aims to systematically summarize the advantages of using a digital publishing platform for scientific and technological journals based on extensible markup language (XML)-integrated production. It also seeks to analyze the effects of the fusion of digital production and new media practices in order to provide a reference for China's digital publication of scientific and technological journals and its combination with new media. Methods: Taking Acta Scientiae Circumstantiae as an example, this study builds a model of digital production and new media fusion publishing for scientific and technological journals based on XML integration by reviewing the shortcomings of traditional production models. The advantages and practical applications of digital production and new media fusion publishing are analyzed. Results: The adoption of an XML-integrated production platform results in producing content once and its diverse publication. Single articles or entire issues can be quickly released, allowing these to be immediately published four months ahead of the network first release and thus shortening the publication cycle. The platform is seamlessly connected with journal websites and WeChat, achieving simultaneous priority publication and full-issue publication on the PC and mobile ends and realizing media convergence and multichannel dissemination. During the initial period, the average downloads per article significantly increased, with single-article downloads reaching 1961 times. Conclusion: Using an XML-integrated production platform can optimize the publishing process, improve the level of digitalization, and increase work efficiency. It helps shorten the publication cycle, accelerate the speed of dissemination, and enhance the academic influence of a journal.
A one-stop solution for generating, inserting, and verifying quick response codes in scientific journals based on Python
Authors: Niu Xinyue , Qi Lijuan , Fang Mei 
Published: December 2024

Background: This study aims to make quick response (QR) code processing operable, reliable, and efficient. It discusses the exploration and practice of QR code processing in Computer Systems & Applications, providing a useful reference for editors. Methods: Common problems encountered when manually handling QR codes are summarized and analyzed. A QR code-integrated tool is designed using Python language to propose an integrated solution for QR codes, and the tool is compared with manual solutions. Results: The self-developed QR code-integrated tool can realize the automatic processing of tasks, such as generating, inserting, and verifying QR codes, thereby achieving high efficiency and reliability. For example, it takes about 2 hours to handle 45 papers by hand, whereas automated operations require only about 30 seconds, without any errors. The use of tools to automatically verify QR codes no longer relies on uniform resource locator (URL) activation, achieving perfect integration between QR code processing flow and the traditional editorial publishing process. Conclusion: Using Python, this study demonstrates that high-quality QR code settings can be achieved efficiently in single articles in scientific journals. Computer automation operations have high efficiency and strong reliability in dealing with repetitive work. Scientific journal editors should think creatively and continuously improve their work efficiency by adopting computer technology to refine workflow.
Technical skills talent development in a vocational undergraduate program: Case study of a modern communication engineering program
Authors: Wang Yongxue , Wu Weiqiang , Wang Sunan 
Published: December 2024

The development of the digital economy represents a strategic decision aimed at addressing the demands of the current scientific and technological revolution and industrial transformation. Vocational undergraduate programs in modern communication engineering play a crucial role in developing high-level technical talent within the information and communication sector to bolster the advancement of the digital economy. This necessitates the delineation of talent development objectives, the methodical formulation of talent training schemes, investigations into synergistic models of industry-education integration, and the establishment of the professional attributes characteristic of vocational undergraduate education. Using the Modern Communication Engineering program at Shenzhen Polytechnic University as a case study, we describe a talent cultivation model and practical experiences within the field of modern communication engineering. This model encompasses the technology-driven, project-based and competency-based integration of practice and experience within a comprehensive curriculum and professional certification system and offers insights into the furtherance of high-quality vocational undergraduate education in modern communication engineering.