bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Clinical Prediction Model to Predict Heparin Treatment Outcomes and Provide Dosage Recommendations: Development and Validation Study
Authors: Li Dongkai , Gao Jianwei , Hong Na , Wang Hao , Su Longxiang , Liu Chun , He Jie , Jiang Huizhen , Wang Qiang , Long Yun , Zhu Weiguo 
Published: May 2021

Background
Unfractionated heparin is widely used in the intensive care unit as an anticoagulant. However, weight-based heparin dosing has been shown to be suboptimal and may place patients at unnecessary risk during their intensive care unit stay.

Objective
In this study, we intended to develop and validate a machine learning–based model to predict heparin treatment outcomes and to provide dosage recommendations to clinicians.

Methods
A shallow neural network model was adopted in a retrospective cohort of patients from the Multiparameter Intelligent Monitoring in Intensive Care III (MIMIC III) database and patients admitted to the Peking Union Medical College Hospital (PUMCH). We modeled the subtherapeutic, normal, and supratherapeutic activated partial thromboplastin time (aPTT) as the outcomes of heparin treatment and used a group of clinical features for modeling. Our model classifies patients into 3 different therapeutic states. We tested the prediction ability of our model and evaluated its performance by using accuracy, the kappa coefficient, precision, recall, and the F1 score. Furthermore, a dosage recommendation module was designed and evaluated for clinical decision support.

Results
A total of 3607 patients selected from MIMIC III and 1549 patients admitted to the PUMCH who met our criteria were included in this study. The shallow neural network model showed results of F1 scores 0.887 (MIMIC III) and 0.925 (PUMCH). When compared with the actual dosage prescribed, our model recommended increasing the dosage for 72.2% (MIMIC III, 1240/1718) and 64.7% (PUMCH, 281/434) of the subtherapeutic patients and decreasing the dosage for 80.9% (MIMIC III, 504/623) and 76.7% (PUMCH, 277/361) of the supratherapeutic patients, suggesting that the recommendations can contribute to clinical improvements and that they may effectively reduce the time to optimal dosage in the clinical setting.

Conclusions
The evaluation of our model for predicting heparin treatment outcomes demonstrated that the developed model is potentially applicable for reducing the misdosage of heparin and for providing appropriate decision recommendations to clinicians.
Estimasi Premature Mortality Cost (PMC) Penyakit Kanker Akibat Perokok Pasif di Indonesia
Authors: Santosa Karina Anindita , Kristina Susi Ari , Wiedyaningsih Chairun 
Published: May 2021

Indonesia merupakan salah satu negara dengan prevalensi perokok terbesar di dunia. Tingginya angka perokok di Indonesia mengakibatkan risiko peningkatan jumlah orang terpapar atau menghirup asap rokok sebagai secondhand smoke. Secondhand smokemerupakan salah satu faktor risiko penyakit kanker. Penelitian mengenai estimasi beban penyakit kanker ini bertujuan untuk melihat seberapa besar angka kematian dan prematuremortality cost penyakit kanker akibat secondhand smokedi Indonesia. Estimasi beban penyakit kanker akibat secondhand smokemerupakan penelitian epidemiologi deskriptif dan estimasi berdasarkan prevalence-baseddengan indikator yang digunakan yaitu angka kematian penyakit kanker akibatsecondhand smokedan premature mortality cost. Angka kematian penyakit kanker akibat secondhand smoke (SAM) diperoleh dengan mengalikan nilai Secondhand smokeAttributable Fractions (SAFs) dengan angka kematian tiap penyakit kanker, dimana nilai SAFs diperoleh dari rumus perhitungan menggunakan data prevalensi secondhand smokedan relative risk tiap penyakit. Premature mortality cost diperoleh dengan mengalikan angka kematian penyakit kanker akibat perokok pasif, angka harapan hidup, dan rata-rata pendapatan masyarakat Indonesia. Jumlah angka kematian tertinggi untuk penyakit kanker akibat secondhand smoke adalah kanker paru (949 kematian), kanker kolon (771 kematian), dan kanker pankreas (371 kematian). Nilai tertinggi dari premature mortality costadalah Rp 56.882.000.000 untuk kanker paru, Rp 51.398.000.000 untuk kanker kolon, dan Rp 22.850.000.000 untuk kanker pankreas. Estimasi beban penyakit kanker akibat secondhand smokeperlu dilakukan untuk membantu pemerintah dalam menentukan program kesehatan dan untuk mengurangi beban penyakit kanker akibat secondhand smokedi Indonesia.
DNA Barcode of Barred Mudskipper (<i>Periophthalmus argentilineatus</i> Valenciennes, 1837) from Tekolok Estuary (West Nusa Tenggara, Indonesia) and Their Phylogenetic Relationship with Other Indonesian Barred Mudskippers
Authors: Rha'ifa Febrina Amaliya , Audrea Deiandra Jasmine , Hakim Lukman , Arisuryanti Tuty 
Published: May 2021

Barred mudskipper (Periophthalmus argentilineatus) has a potency to be developed as protein for human consumption and ornamental fish. The fish also has an important role in mangrove ecosystems. Nevertheless, many barred mudskippers have been considered a cryptic species. Therefore, accurate identification is needed to clarify species identification of the barred mudskipper using DNA barcoding. This research aimed to identify barred mudskippers from Tekolok Estuary (East Lombok, West Nusa Tenggara, Indonesia) using COI mitochondrial gene as a DNA barcode and analyze genetic relationship with other barred mudskippers from several regions of Indonesia recorded in GenBank. This study used a PCR method with universal primers FishF2 and FishR2. The data was then analysed using DNASTAR, BLAST, Mesquite, MEGA, DnaSP, BEAST, GenAlEx, and NETWORK. The results revealed that barred mudskipper from Tekolok Estuary has been verified as Periophthalmus argentilineatus. The results also exhibited that P. argentilineatus from Tekolok Estuary has a close genetic relationship to P.argentilineatus from Tukad Bilukpoh (Jembrana, Bali). In addition, phylogenetic analysis showed that P.argentilineatus from Indonesia consisted of two clades with a genetic distance of approximately 6.64%. This analysis revealed evidence of the cryptic diversity of P.argentilineatus from Indonesia. Further detailed studies are needed to clarify whether Indonesian P.argentilineatus should be categorized into more than one species or single species with several subspecies.
Versos e gritos: memória poética da Guerra Colonial
Authors: Ribeiro Margarida Calafate , Vecchi Roberto 
Published: May 2021

O artigo analisa a memória poética da experiência da Guerra Colonial identificando expressões díspares do poético: poemas de valor predominantemente documental; uma poesia da época que integra a Guerra Colonial e também a expõe pelo canto; e uma poesia de poetas da Guerra Colonial. O arquivo poético construído pela Antologia da Memoria Poética da Guerra Colonial, organizada pelos autores deste artigo demonstra que só o advérbio “Ainda” – aquele com que Manuel Alegre fecha uma viagem sem regresso – mostra como a guerra continua por dentro das palavras, por dentro dos versos, denunciando a profundidade da inscrição da guerra no presente.
"Arado" de A. M. Pires Cabral: uma paisagem de proximidade
Authors: Alves Isabel Maria Fernandes 
Published: May 2021

Partindo de Arado, publicado em 2009, esta reflexão pretende considerar a obra poética de A. M. Pires Cabral à luz da Ecocrítica. Nesse sentido, começa-se por referir as paisagens que são pertença do poeta e o modo como elas, fazendo-se texto, são o próprio poeta. Apresenta-se depois a leitura de alguns poemas tendo como moldura crítica a ideia, explorada pela ecocrítica, de que a linguagem pode exercer um forte domínio sobre o modo como se lê e interpreta o território, a paisagem. Sensível às ligações entre o homem e o espaço físico que habita, a ecocrítica permite salientar uma perspectiva importantíssima na obra de Pires Cabral: o reconhecimento de que o homem molda o mundo que o envolve, mas, nessa mudança, a si mesmo se transforma também.
Disparitas Pidana Terhadap Pelaku Kasus Tindak Pidana Penganiayaan
Authors: Zilvia Rahmi , Haryadi Haryadi 
Published: May 2021

ABSTRAK
Penelitian ini bertujuan untuk menganalisis mengenai dasar pertimbangan hakim dalam menjatuhkan pidana terhadap pelaku tindak pidana penganiayaan. Penelitian ini bersifat penelitian yuridis empiris. Berdasarkan hasil penelitian disimpulkan bahwa telah terjadi disparitas pidana. Disparitas pidana terjadi karena hakim belum mempertimbangkan fakta persidangan tentang akibat dari perbuatan pidana. Pada Kasus pertama tindak pidana mengakibatkan luka ringan dan tanpa senjata tajam. Kasus kedua tindak pidana mengakibatkan luka berat dengan menggunakan senjata tajam. Hakim menjatuhkan pidana penjara lebih berat pada kasus pertama yang seharusnya lebih ringan dari kasus kedua. Seharusnya hakim dalam menjatuhkan pidana hendaknya tidak hanya mempertimbangkan fakta yuridis, tetapi juga dengan cermat mempertimbangkan fakta persidangan dan fakta sosiologis.
ABSTRACT
This study aims to analyze the basis of judge's considerations in imposing of sanction against Maltreatment perpetrators. This research are empirical. The study concludes that there has been a criminal sanction disparity due to judge's failure to consider the facts of the trial regarding the consequences of criminal acts. In the first case, the crime caused minor injuries, while the second case caused serious injuries. However, the judge sentenced him to with longer time in prison in the first case than that of the second case. It is suggested that judges consider not only judicial facts in judging juridical facts, but also the trial and sociological facts.
Pelaksanaan Hak Tahanan (Tantangan dan Permasalahan)
Authors: Nababan Monica Dwi Putri , Nawawi Khabib 
Published: May 2021

ABSTRAK
Penelitian ini bertujuan untuk membahas pelaksanaan hak tahanan dan kendala yang dihadapi Lembaga Pemasyarakatan dalam memberikan hak tahanan. Penelitian ini bersifat yuridis empiris. Hasil penelitian menunjukkan bahwa pelaksanaan hak tahanan masih belum efektif terkait beberapa hak, diantaranya yaitu hak untuk melakukan ibadah yakni terkait melaksanakan tempat ibadah tidak tersedia bagi semua agama yang diakui di Indonesia, kurangnya tenaga medis bagi layanan kesehatan, hak menyampaikan keluhan dimana keluhan tahanan kurang mendapat tanggapan dari petugas lapas dan hak mendapatkan kunjungan yang kurang nyaman serta hak mendapatkan politik. Kendala yang dialami oleh Lembaga Pemasyarakatan dalam memberikan hak tahanan diantaranya: kapasitas berlebih Lembaga Pemasyarakatan, keterbatasan sarana dan prasarana yang mendukung di Lembaga Pemasyarakatan, kurangnya tenaga pengajar pembinaan, tenaga kesehatan dan tenaga bantuan lainnya, kurangnya anggaran dana serta tidak semua tahanan bersedia mengikuti program yang diberikan oleh petugas Lembaga Pemasyarakatan
ABSTRACT
This study aims to discuss the implementation of prisoners' rights and the constraints faced by the Penitentiary in providing prisoners' rights. This research is empirical research. The results showed that the implementation of the right of detainees was still ineffective in relation to several rights, including the right: to conduct worship, namely related to carrying out places of worship not available to all religions, lack of medical personnel for health services, the right to submit complaints where complaints from prisoners did not get a response from prison officers and the right to get uncomfortable visits and the right to get politics. Constraints experienced by Penal Institutions in granting prisoners' rights include: overcrowding capacity of Penitentiaries, limited facilities and infrastructure that support in Penitentiaries, lack of guidance teaching staff, health workers and other aid workers, lack of budget funds and not all prisoners are willing to participate in programs that given by the Penitentiary officer.
Pengaturan Uang Pengganti Sebagai Pidana Tambahan dalam Tindak Pidana Korupsi
Authors: Wendy Wendy , Najemi Andi 
Published: May 2021

ABSTRAK:
Artikel ini bertujuan untuk memahami dan mengevaluasi regulasi terkait pidana uang pengganti dalam tindak pidana korupsi serta untuk memahami dan mengetahui penerapan pidana uang pengganti terhadap pelaku tindak pidana korupsi. Penelitian ini merupakan penelitian hukum normatif. Dari penelitian ini ditemukan, pidana uang pengganti berstelsel pidana tambahan namun bobot pidananya dapat lebih tinggi dari pada pidana denda yang berstelsel pidana pokok, dan kurang maksimal dalam penerepan uang pengganti. Saran perlu adanya pembaharuan hukum terkait pidana uang pengganti sebagai pidana tambahan.
ABSTRACT:
This article aims to understand and evaluate regulations relating to substitute criminal money in criminal acts of corruption as well as to understand and know the application of criminal replacement money against perpetrators of corruption. This research is a normative legal research. From this study it was found, the criminal money substitute was additionally criminal, but the criminal weight could be higher than the criminal fine which was based on principal criminal, and less than the maximum in forwarding the replacement money. Suggestions are the need for legal reform related to criminal money as an additional crime
Penegakan Hukum Pidana Mengenai Mobil Barang Dipergunakan Untuk Angkutan Orang
Authors: Anggraeni Ussi Astika , Hafrida Hafrida , Arfa Nys. 
Published: May 2021

This study aims to identify and analyze criminal law enforcement and obstacles in criminal law enforcement to Article 137 Paragraph (4) of the Law on Road Traffic and Transportation in the jurisdiction of the Kuala Tungkal District Court. The research method used was juridical empirical and the sampling method was carried out by using purposive sample and simple random sampling method. Constraints faced in enforcing the criminal law against Article 137 Paragraph (4) of the Law on Traffic and Road Transportation in the jurisdiction of the Kuala Tungkal District Court, among others, the legal substance in the criminal provisions is limited to imprisonment and very light and cheap fines, limited personnel of the Traffic Police in conducting surveillance, lack of guard posts and official vehicles owned by the Traffic Police. so it is necessary to increase the socialization or legal counseling to the public regarding Article 137 paragraph (4) of the Law on Road Traffic and Transportation, and the government is responsible for the provision of proper transportation vehicles for people to create orderly, safe and comfortable traffic in the community.
Abstrak
Penelitian ini bertujuan untuk mengetahui dan menganalisis penegakan hukum pidana dan kendala dalam penegakan hukum pidana terhadap Pasal 137 Ayat (4) Undang-Undang Tentang Lalu Lintas dan Angkutan Jalan di wilayah hukum Pengadilan Negeri Kuala Tungkal. Metode penelitian yang digunakan adalah Yuridis Empiris dan tata cara penarikan sampel dilakukan dengan metode Purposive Sampel dan Simple Random Sampling. Kendala yang dihadapi dalam penegakan hukum pidana terhadap Pasal 137 Ayat (4) Undang-Undang Tentang Lalu Lintas dan Angkutan Jalan di wilayah hukum Pengadilan Negeri Kuala Tungkal, diantarnya substansi hukum pada ketentuan pidananya hanya terbatas pada pidana kurungan dan denda yang sangat ringan dan murah, terbatasnya personil Polisi Lalu Lintas dalam melakukan pengawasa, kurangnya pos penjagaan dan kendaraan dinas yang dimiliki oleh Polisi Lalu Lintas. sehingga perlu ditingkatkan sosialisasi atau penyuluhan hukum kepada masyarakat mengenai Pasal 137 ayat (4) Undang-Undang Tentang Lalu Lintas dan Angkutan Jalan, serta pemerintah bertanggung jawab terhadap penyediaan mobil angkutan orang yang layak agar terciptanya lalu lintas yang tertib, aman dan nyaman dalam masyarakat.
Penyidikan Tindak Pidana Prostitusi secara Online
Authors: Amilia Yolla Fitri , Haryadi Haryadi , Wahyudi Dheny 
Published: May 2021

This article aims to find out and analyze the process of investigating criminal acts of prostitution online in the jurisdiction of the Jambi City Police and find out what are the obstacles in the process of investigating criminal acts of prostitution online in the jurisdiction of the Jambi City Police Resort. The results of the study concluded that the online prostitution crime investigation process carried out by the Jambi City Resort Police officers in overcoming online prostitution crimes, the investigators carried out the investigation process by disguising themselves and trapping the perpetrators. In this case, the operational targets of the Jambi City Resort Police are commercial sex worker service providers (pimps). Furthermore, related to obstacles in the process of investigating criminal acts of prostitution online in the jurisdiction of the Jambi City Police, in fact, investigators in the investigation process have difficulty collecting evidence, and lack of human resources such as IT experts at the Jambi City Police Resort.
Abstrak

Artikel ini bertujuan untuk mengetahui dan menganalisis proses penyidikan prostitusi secara online di wilayah hukum Kepolisian Resor Kota Jambi dan mengetahui apakah hambatan dalam proses penyidikan tindak pidana prostitusi secara online di wilayah hukum Kepolisian Resor Kota Jambi. Hasil penelitian disimpulkan bahwa proses penyidikan tindak pidana prostitusi secara online yang dilakukan oleh aparat Kepolisian Resor Kota Jambi dalam menanggulangi prostitusi secara online, penyidik melakukan proses penyidikan dengan cara penyamaran dan penjebakan terhadap pelaku. Dalam hal ini yang menjadi target operasi penyidik Kepolisian Resor Kota Jambi ialah penyedia jasa pekerja seks komersil (mucikari). Selanjutnya, terkait hambatan dalam proses penyidikan tindak pidana prostitusi secara online di wilayah hukum Kepolisian Resor Kota Jambi pada kenyataannya, penyidik dalam proses penyidikan kesulitan dalam mengumpulkan alat bukti, dan kurangnya sumber daya manusia seperti ahli IT di Kepolisian Resor Kota Jambi.
Edward Everett Gore: Contributions of an Early 20th Century CPA and Civic Leader
Authors: Flesher Dale L. , Previts Gary John 
Published: May 2021

ABSTRACT
Edward Everett Gore was the president of the American Institute of Accountants (now AICPA) from 1922 to 1924 He served on the AICPA Council from 1916 until his death in 1935. At the same time he was leading the accounting profession, he was the president of the Chicago Association of Commerce. He was later founder and president of the Chicago Crime Commission during the era when Alphonse Capone was terrorizing the city. He was responsible for the passage of the first Illinois CPA law and for the establishment of the Journal of Accountancy and for the AICPA Benevolent Fund. He wrote portions of the 1913 tax law and campaigned for the establishment of the Internal Revenue's Board of Tax Appeals (Tax Court). Gore entered public accounting in 1897 and later became a partner in the venerable firm of Barrow, Wade & Guthrie. He left that firm to form Smart, Gore & Company in 1922.
Reporting 4.0: Business Reporting for the Age of Mass Customization
Authors: Alles Michael G. , Dai Jun , Vasarhelyi Miklos A. 
Published: May 2021

ABSTRACT
Financial reporting has evolved over centuries in distinct stages. The first reports (Reporting 1.0) were the trial balances ensuring that debits equaled credits, using the terminology popularized by Pacioli. The next major innovation was formalized in the Great Depression, with Reporting 2.0 being the standardized and audited financial statements. Reporting 3.0 evolved as technology was used to augment that reporting process with ERP-based data and XBRL. Today, technology is still relying on the automation of existing processes in Reporting 3.0. This paper proposes the move to Reporting 4.0, where technology will change reporting as fundamentally as Industry 4.0 is changing business operations. What characterizes Reporting 4.0 is the application of the intelligence inherent in 21st-century technology to create an app-based reporting system characterized by mass customization: the ability for reports to be tailored to meet the needs of the heterogeneous stakeholder community of the multi-objective modern enterprise.
Company-Specific Risk and Small Company Valuation
Authors: Cooper Lauren A. , DiGabriele James A. , Riley Richard A. , Sorensen Trevor L. 
Published: May 2021

ABSTRACT
A significant role of forensic accountants is valuing privately held companies (Domino, Stradiot, and Webinger 2015; Trugman 2017; Allee, Erickson, Esplin, and Yohn 2020). This study examines the role of private company transaction features on the composition of capitalization rates, industry risk premiums, and company-specific risks for private companies. We find that company-specific risk accounts for at least 50 percent of the capitalization rate. Further, while the industry risk premium represents less than 2 percent of the capitalization rate, it is significantly associated with company-specific risk, suggesting that industry risk is an important determinant of company-specific risk. Finally, we find evidence that several private company transaction features are associated with company-specific risk. These findings represent an important step in understanding capitalization rates and company-specific risk for private company valuation. These findings should also help practitioners and academics better determine the cost of capital for private companies.
Data Availability: Data are available from public sources cited in the text.
JEL Classifications: G12; G14; G32; G34; G39.
A Preliminary Examination of the Effectiveness of Assessment Questions in Detecting Dishonest Behavior
Authors: Jensen Kevan L. , Smith Mark W. 
Published: May 2021

ABSTRACT
This study examines the effectiveness of assessment questions in distinguishing perpetrators of dishonest acts from non-perpetrators. Virtually all fraud examination or forensic accounting textbooks teach that assessment questions are useful in identifying perpetrators. Yet there are no scientific studies that provide empirical support for this notion. Using cheating and shoplifting as examples of dishonest acts (i.e., fraud), and using a series of studies wherein we anonymously put assessment questions to university students, we find that students who have perpetrated dishonest acts respond differently to assessment questions than do students who have not perpetrated those acts. Cheaters tend to respond that cheating is more common than do non-cheaters, and cheaters tend to respond that punishments for cheating should be less severe than do non-cheaters. Results for shoplifters versus non-shoplifters are similar. Some assessment questions are more effective than others, and how questions are framed seems to be relevant.