bluuebunny/crossref_metadata_2025_split huggingface dataset:
One coast, two systems: Regional innovation systems and entrepreneurial discovery in Western Norway
Authors: Deegan Jason , Solheim Marte C. W. , Jakobsen Stig‐Erik , Isaksen Arne 
Published: December 2021

AbstractThis paper introduces an analytical framework for understanding how specialized and diversified regional innovation system (RIS) differ in the way an entrepreneurial discovery process (EDP) is likely to unfold. To analytically explore the proposed framework, we deploy a sequential explanatory design approach, using quantitative data to analyze the regional industry structure of the city regions of Bergen and Stavanger in Western Norway, followed by a qualitative analysis of interviews with key stakeholders in both regions. We find that the city regions face unique challenges that align with an understanding of their respective RIS categorization, providing evidence that the framework proposed serves as a useful guide in understanding the development of an EDP.
Performance Analysis ofANNPrediction for Groundwater Level ConsideringRegional‐SpecificInfluence Components
Authors: Kim Incheol , Lee Junhwan 
Published: December 2021

AbstractGroundwater level (GWL) varies periodically or non‐periodically with various factors including precipitation, river stage (RS) change, sea level, and dewatering activities. In this study, the effect of influence components on the prediction of GWL using an artificial neural network (ANN) was investigated. Six regions with different hydrologic and geologic conditions were collected and adopted in the investigation using various input combinations. In urban areas with a high surface paved ratio, GWL was mainly affected by RS. In rural areas, the permeability of ground showed a significant impact on GWL. For such cases, the moving average (MA) was a suitable component as it could reflect both time lag and the effect of preceding precipitation. It was shown that site‐specific influence component should be firstly identified and introduced into input for more enhanced and reliable prediction of GWL using ANN. The effect of learning data length (LDL) was less significant. In urban and rural areas, the introduction of RS and MA into ANN input significantly improved the prediction performance, respectively, which was consistent with the correlation analysis of GWL influence components.
Ability of volume measures of hydronephrosis to predict need for surgery and evaluate renal function in children with ureteropelvic junction obstruction
Authors: Bai Kaiping , Hou Yanping , Zhang Zhiyuan , Xing Xiaoyu , Zhu Weiwen , Zou Xiangyu , Sun Jie 
Published: December 2021

ObjectiveTo explore the efficacy of quantitative renal volume measures on magnetic resonance urography images in predicting need for surgery among children with ureteropelvic junction obstruction and their ability to evaluate renal function.MethodsA total of 88 cases of hydronephrosis in 50 patients were collected between 1 April 2018 and 31 March 2020, including 30 operated kidney and 58 unoperated kidney cases. Clinical data were collected, and quantitative analysis of magnetic resonance urography was performed. Renal volume, hydronephrosis volume and the volume ratio of hydronephrosis (hydronephrosis volume/renal volume) were measured and calculated. We analyzed the relationships between the above indices in the two groups and compared these with renal function.ResultsCompared with the unoperated kidney group, hydronephrosis volume, renal volume and hydronephrosis volume/renal volume of the operated kidney group increased significantly. Hydronephrosis volume (area under the curve 0.972, 95% confidence interval 0.943–1.000; P < 0.001) and hydronephrosis volume/renal volume (area under the curve 0.968, 95% confidence interval 0.939–0.998; P < 0.001) were superior to ultrasonography and renal function examination in predicting the probability of surgery, and their sensitivity values (hydronephrosis volume/renal volume: 96.67%; hydronephrosis volume: 93.33%) were higher than those of the renal function test (50%). There was a significant difference among different renal function groups in the pairwise comparison of hydronephrosis volume and hydronephrosis volume/renal volume (P < 0.05).ConclusionQuantitative volume measures of hydronephrosis by magnetic resonance urography had a greater ability to predict need for surgery than ultrasonography and dynamic renal imaging, and it can be used as method by which to evaluate surgery. Hydronephrosis volume and hydronephrosis volume/renal volume have greater predictive ability, and play an important role in the deterioration of renal function.
A metaheuristic for crew scheduling in a pickup‐and‐delivery problem with time windows
Authors: Lucci Mauro , Severín Daniel , Zabala Paula 
Published: December 2021

AbstractA simultaneous vehicle routing and crew scheduling problem (SVRCSP) consists of planning routes for a fleet of vehicles and scheduling their crews, with the particularity that the vehicle–crew correspondence is not fixed through time. This allows a greater planning flexibility and a more efficient use of the fleet, but in counterpart it requires high synchronization. In this work, an SVRCSP is presented, where long‐distance pickup‐and‐delivery requests must be fulfilled over a multiday planning horizon, subject to several constraints such as multiple time windows, hour of services regulation, among others. Crews can be composed of one or two drivers and any of them can be relieved in a given set of locations. Also, they are allowed to travel between locations with noncompany shuttles. The objective is to minimize the cost of travel in company and noncompany vehicles, which depends on the distance, and the penalization for completing requests with delay. A two‐stage sequential approach is applied: a set of truck routes is computed in the first stage and a set of driver routes consistent with the previous routes is obtained in the second stage. An algorithm based on the GRASP × ILS metaheuristic, embedded with a repair heuristic to facilitate the construction of initial solutions, is proposed and evaluated for the latter stage. High‐quality solutions were found for instances generated with up to 3000 requests and a planning horizon of one to four weeks spread over 15 Argentine cities in less than an hour. Additionally, the possibility of carrying an additional driver reduced the cost of external shuttles by 2.25 times on average compared to individual crews and, in some cases, removed this cost completely.
Experiment and simulation of infrared emissivity properties of doped LaAlO3
Authors: Liu Qingsheng , Cheng Huajin , Tu Tao 
Published: December 2021

AbstractIn this study, LaAlO3 doped with Sr/Co/Mn was prepared by sol‐gel method, with its infrared (IR) radiative properties and variation mechanism investigated by X‐ray powder diffraction, X‐ray photoelectron spectroscopy, IR, scanning electron microscopy. Meanwhile, the electronic band structure was simulated by Cambridge Serial Total Energy Package. The conclusions are as follows: the order of emissivity in the near‐IR band is La0.67Sr0.33Al0.67Mn0.33O3> La0.67Sr0.33Al0.67Co0.33O3> LaAl0.67Mn0.33O3> LaAl0.67Co0.33O3> LaAlO3. In 0–2.5 μm at room temperature, the emissivity of La0.67Sr0.33Al0.67Mn0.33O3 can reach 0.9504. The emissivity increase mechanism lies in the further free carrier absorption caused by numerous small polarons formed by the Sr‐Mn co‐doping and increased concentration of electron‐oxygen vacancies. Meanwhile, the Sr‐Mn co‐doping causes lattice distortion and strengthens the lattice vibration absorption. The band gap of La0.67Sr0.33Al0.67Mn0.33O3 is 0.910 eV, much smaller than 3.445 eV of LaAlO3, favorable to the valence band electron transition, generating more electron‐oxygen vacancy pairs and promoting free carrier absorption. La0.67Sr0.33Al0.67Mn0.33O3 conduction band migrates to the lower energy region, while Mn3d impurity energy level appears. Thanks to the band gap reduction, dielectric function imaginary peaks, and absorption coefficient peaks are red‐shifted. Due to its high emissivity, La0.67Sr0.33Al0.67Mn0.33O3 has a high utilization value and broad potential application.
Conducting theory‐based qualitative interviews with adults with intellectual disabilities and their carers: Adaptations to facilitate participation
Authors: Bains Kiran K. , Turnbull Triece 
Published: December 2021

AbstractBackgroundAdults with mild–moderate intellectual disabilities have difficulties in accessing traditional evidence‐based health promotion initiatives despite experiencing health disparities; yet there are few studies with this group and their carers exploring how their needs can be met.MethodThis study adapted a behaviour change theory‐based approach to interview this group and their carers and ascertain if this method was feasible and appropriate to explore how healthier behaviour uptake could be improved amongst adults with intellectual disabilities.ResultsA community‐based, staged recruitment process and iterative approach to data collection and analysis supported successful participation amongst adults with intellectual disabilities in behaviour‐change theory‐based interview research. Methodological adaptations enabled richer data collection amongst adults with mild–moderate intellectual disabilities and carers.ConclusionsIt is feasible and important to include adults with intellectual disabilities in qualitative health research that uses theory‐based complex constructs to inform development of person‐centred health promotion interventions with this underserved cohort.
Lower Bound Uncertainty and Long‐Term Interest Rates
Authors: GRISSE CHRISTIAN 
Published: December 2021

AbstractNominal interest rates are constrained by an effective lower bound, but the level of the lower bound is uncertain. This paper uses a simple shadow rate term structure model to study how lower bound uncertainty affects long‐term interest rates. A decline in lower bound uncertainty, in the sense of a mean‐preserving contraction, is associated with a drop in expected short rates. The effect on the variance of short rates, and hence the term premium, is ambiguous. A calibration to Canadian data suggests that a decline in lower bound uncertainty is associated with a modest drop in interest rates.
Caveolin‐1 promotes cancer progression via inhibiting ferroptosis in head and neck squamous cell carcinoma
Authors: Lu Tingwei , Zhang Zhen , Pan Xinhua , Zhang Jianjun , Wang Xu , Wang Miaochen , Li Huasheng , Yan Ming , Chen Wantao 
Published: December 2021

AbstractBackgroundHead and neck squamous cell carcinoma (HNSCC) is an aggressive disease worldwide. Much progress has been made in exploring mechanisms and improving the therapy of HNSCC, but only a few studies have focused on the role of ferroptosis on HNSCC progression. The current study aimed to reveal the underlining mechanisms that caveolin‐1 (CAV1)‐ROS (reactive oxygen species)‐ferroptosis axis affect the process of HNSCC and discover novo therapeutic targets or strategies.MethodsThe role of CAV1 in ferroptosis was analyzed by FerrDb, and its clinical significance was examined by TCGA dataset of HNSCC. The expressions of caveolin‐1 (CAV1) in HNSCC tissues were measured by immunohistochemistry, western blot, and real‐time PCR assay. Three siRNA sequences were designed to silence CAV1 mRNA in HNSCC cells. Cell proliferation, colony formation, wound‐healing, and transwell assays were used to examine the proliferation, migration, and invasion of cancer cells. ROS evaluation and intracellular Fe2+ content assays were performed to examine the levels of ferroptosis.ResultsThrough the analysis with published data, CAV1 was found to overexpress in HNSCC than normal tissues, and was one of the vital suppressors of ferroptosis pathway. Our study showed that CAV1 was over expressed in HNSCC tissues and the high level of CAV1 predicted poorer prognosis. Further experiments indicated that CAV1 could inhibit the ferroptosis of cancer cells and promote the proliferation, migration and invasion.ConclusionsOverexpression of CAV1 in HNSCC inhibited the process of ferroptosis, leading to aggressive phenotypes, as well as worse prognosis. The regulatory pathway of CAV1 and ferroptosis are potential targets for designing diagnostic and combined therapeutic strategies for HNSCC patients.
Compassion fatigue in mental health nurses: A systematic review
Authors: Marshman Cameron , Hansen Alison , Munro Ian 
Published: December 2021

Accessible SummaryWhat is known on the subject?

Compassion fatigue is the result of the unique stressors inherent in caregiving work, leading to a loss of compassion in clinical practice that may result in negative outcomes for mental healthcare consumers.

Compassion fatigue has clear emotional and physical costs and significant impacts on staff recruitment and retention.

What the paper adds to existing knowledge?

This review is the first to evaluate the quantitative literature on compassion fatigue in mental health nurses.

Research on compassion fatigue in mental health nurses does not accurately account for the unique care relationship between nurse and consumer.

Competency‐based education, strong mental health nurse leadership, positive organizational cultures, clinical supervision and reflection alongside individual self‐care strategies may mitigate compassion fatigue.

What are the implications for future practice?

Resources are urgently needed for education and workforce development that addresses compassion fatigue in mental health nurses.

Interventions addressing the physical, cognitive and emotional demands of care work are needed to ensure mental health nurses have the capability to provide sustainable compassionate care to consumers.

AbstractIntroductionAlthough compassionate care is an essential component of mental health nursing, understandings of the impact of compassion fatigue is poorly understood.Aims/QuestionsTo examine and synthesize available data on the prevalence of compassion fatigue within mental health nurses and consider what variables impact compassion fatigue.MethodA search of MEDLINE, EMBASE, PsychINFO, Emcare, Web of Science, Scopus, CINAHL and grey literature for articles published between 1992 and February 2021 was conducted. Data were extracted from articles meeting inclusion criteria and integrated using narrative synthesis.ResultsTwelve articles were included. Prevalence of compassion fatigue ranged from low to high. Variables were identified that may mitigate the risk of compassion fatigue. Strong leadership and positive workplace cultures, clinical supervision, reflection, self‐care and personal well‐being may protect mental health nurses against compassion fatigue.DiscussionFuture research is needed on mental health nurses lived experience of compassion fatigue and their understandings of compassion.Implications for PracticeInterventions should focus on increasing awareness of compassion fatigue and building individual and organizational resilience. Both organizations and individuals should be aware of the role they play in maintaining the capacity and capability for mental health nurses to provide sustainable and compassionate mental healthcare.
The Process of Thinking During the Care Work of Care Workers1
Authors: Tsukamoto Erika , Ono Michikazu , Oosono Yasufumi 
Published: December 2021

AbstractOur research aims to clarify the thinking processes involved in care work of care workers who care for the elderly. We conducted interviews with 12 care workers working in an elderly day‐care center and analyzed the data with the Modified Grounded Theory Approach (M‐GTA). As a result, 26 concepts were generated. Next, these concepts were divided into eight categories and further summarized into four central categories. The structure of the care worker's thinking was explained according to four central categories: Think about care attitude, Determine care attitude, Care for the users, and Foundation of care. From these results, we confirmed that care workers attach great importance to maintaining their three central categories of thinking processes and foundation of care to provide quality care to the users. We also confirmed that the three central categories are divided into positive and negative concepts that affect the quality of care for the users. Accordingly, to provide high‐quality care for elderly users, it is necessary to consider the organizational mechanisms that support care workers’ three thinking processes and foundation of care.
Historical Fundamentalism? Christian Nationalism and Ignorance About Religion in American Political History
Authors: Perry Samuel L. , Braunstein Ruth , Gorski Philip S. , Grubbs Joshua B. 
Published: December 2021

AbstractReligious right leaders often promulgate views of Christianity's historical preeminence, privilege, and persecution in the United States that are factually incorrect, suggesting credulity, ignorance, or perhaps, a form of ideologically motivated ignorance on the part of their audience. This study examines whether Christian nationalism predicts explicit misconceptions regarding religion in American political history and explores theories about the connection. Analyzing nationally representative panel data containing true/false statements about religion's place in America's founding documents, policies, and court decisions, Christian nationalism is the strongest predictor that Americans fail to affirm factually correct answers. This association is stronger among whites compared to black Americans and religiosity actually predicts selecting factually correct answers once we account for Christian nationalism. Analyses of “do not know” response patterns find more confident correct answers from Americans who reject Christian nationalism and more confident incorrect answers from Americans who embrace Christian nationalism. We theorize that, much like conservative Christians have been shown to incorrectly answer science questions that are “religiously contested,” Christian nationalism inclines Americans to affirm factually incorrect views about religion in American political history, likely through their exposure to certain disseminators of such misinformation, but also through their allegiance to a particular political‐cultural narrative they wish to privilege.
Making sense of the new: Progress of modernity in colonial Odisha (part II)
Authors: Satpathy Sumanyu 
Published: December 2021

AbstractThe first part of the article examined the cross‐cultural semantics of the term modernity in the vernacular writing of the English‐educated Odia intellectuals. It also threw light on the way the Odia elite, in the process of conceptualizing the new discourse and experience of modernity, came up with new terms such as adhunik/adhunikata as vernacular equivalents of modern/modernity. In this second part, the emphasis is on empirical and everyday manifestations of modernity in Odisha. It examines how the adhunik/modern came to be understood and internalized in vernacular idioms and the way it took a somewhat different trajectory than that in the rest of the Bengal Presidency of which some territories of Odisha were then a significant part. The article argues that the English‐educated Odias periodically questioned aspects of the new, highlighting older values, and deploying the lessons of value modernity/adhunikata in its abstraction primarily to promote Odia language and literature, and to press demands for welfare measures in the Odia speaking tracts.
When do autopolyploids need poly‐sequencing data?
Authors: Jighly Abdulqader 
Published: December 2021

AbstractThe sequencing depth required to genotype autopolyploid populations is a very controversial topic. Different studies have adopted variable depth values without a clear guide on the optimal sequencing depth value. Many studies suggest high depth thresholds for different ploidies that may not be practical and substantially increase the overall genotyping cost for different projects. However, such conservative thresholds may not be required to achieve the most common research goals. In fact, some recent reports in the field of quantitative genetics found that much lower sequencing depth thresholds could achieve the same accuracy as high depth thresholds. In this manuscript, I discuss when researchers need to use stringent sequencing depth thresholds and when they can use more relaxed ones. I support my argument by calculating the probabilities of sampling different homologues at a given sequencing depth. I also discuss the uses and the uncertainty in calculating a continuous allelic dosage as the proportion of sequencing reads that hold the alternative allele, which is becoming a common method now in quantitative genetics to replace discrete dosage estimation.
Risk factors of severe blastomycosis and comparison of diagnosis and outcomes between immunocompetent and immunocompromised patients
Authors: Villacorta Cari Evelyn , Leedy Nicole , Ribes Julie A. , Soria Jaime , Myint Thein 
Published: December 2021

AbstractBackgroundBlastomycosis is an endemic fungal infection that causes pulmonary and systemic disease. It can occur irrespective of the patient's immune status. The risk factors associated with the severity of the disease are not well studied.MethodsThis is a retrospective study of patients admitted with blastomycosis at the University of Kentucky Hospital from 2004 to 2019. Logistic regression was used to identify variables associated with severe blastomycosis.ResultsA total of 76 patients were identified; 22 (28.9%) had at least one immunosuppressive condition. Pulmonary blastomycosis was reported in 49/76 (65%) of the patients and disseminated infection in 27/76 (35.5%). All diagnostic tests were not significantly different in diagnostic results in immunocompromised vs immunocompetent patients. Cultures and histopathology were positive in 56/61 (91.8%) and 54/63 (85.7%) respectively. Blastomyces or Histoplasma antigen test was positive in 13/17 (76.4%) in immunocompromised patients compared to 26/42 (61.9%) in immunocompetent patients. Immunocompromised patients were more likely to be admitted to the hospital and ICU compared to immunocompetent patients. In the multivariate analysis, pulmonary multilobar disease (RR 5.68; 95% CI 2.13–15.15), obesity (RR 2.39; 95% CI 1.26‐4.51), diabetes mellitus (RR 3.50; 95% CI 1.38‐8.90) and immunosuppression (RR 2.28; 95% CI 1.14‐4.56) were significant independent risk factors for severe blastomycosis. Inpatient mortality proportion was higher in immunocompromised patients but not statistically significant.ConclusionPulmonary multilobar disease, obesity, diabetes mellitus and immunosuppression were risk factors associated with severe blastomycosis. Immunocompromised patients required more frequent hospitalisations compared to immunocompetent patients.