bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative evaluation of serum calcitonin gene related peptide level in patients with migraine headache with and without aura
Authors: Rezaee Mostafa , zadeh Nahid Ashja , Izedi Sadegh , Fakhri Farinaz 
Published: February 2021

Abstract
Background

During a migraine attack, trigeminal activation results in the release of calcitonin gene-related peptide (CGRP), which stimulates the release of inflammatory cytokines playing an important role in migraine. We analyze the serum level of CGRP between two groups of migrainous patients (with aura and without aura)
Materials and Methods

Thirty six migraine patients (included 18 patients with aura and 18 without aura) additionally 18 healthy volunteers consisted control group were selected from the clinic of Neurology, Shiraz University of Medical Sciences, Shiraz, Iran, between March 2020 and November 2020. The CGRP level were determined from the sera of patients with migraine and control subjects by enzyme-linked immunosorbent assay kits. Spearman's rank correlation coefficient was also determined to calculate the correlation between CGRP and clinical findings.
Results

The level of CGRP in groups were significantly different between groups (P = 0.00). Also, the level of CGRP in aura group were significantly higher than non-aura group (P = 0.045). The Spearman’s correlation coefficient revealed a positive and significant correlation between the CGRP concentration and age (p = 0.042, r = 0.172), BMI (p = 0.013, r = 0.08), VAS (P = 0.006 ,r = 0.09), frequency of attacks (p = 0.005, r = 0.9), duration of each attack (p = 0.016, r = 0.23), Migraine Disability Assessment Scale.(p = 0.00, r = 0.785), average of number of Medication (p = 0.00, r = 0.694). However, no significant correlation was observed with gender. (P > 0.05 )
Conclusions

In our study, we found migraine patients had a higher CGRP level than healthy controls and the level of CGRP was related significantly with the duration, BMI, frequency of headache, age, number of headaches per day. In conclusion, our results confirmed that CGRP may be involved in the pathogenesis of migraine attacks and related with the multiple clinical characteristics.
Inflammatory Myofibroblastic Tumor of the Urinary Bladder with Atypical Clinical and Pathological Features: a Case Report
Authors: Xingwang Zhu , Yixiang Wang , Yili Liu 
Published: February 2021

Abstract
Background: The inflammatory myofibroblastic tumor (IMT) of urinary bladder is very rare, this case and often misdiagnosed as bladder cancer. We report a patient with atypical clinical features with dysuria and lower abdominal pain. Case presentation: A 32-year-old man presented with dysuria and lower abdominal pain. Computed tomography (CT) demonstrated that a solitary non-papillary tumor was located at the wall of the bladder dome. Partial cystectomy was successfully managed. Immunohistochemically, positivity of the tumor cells for anaplastic lymphoma kinase (ALK), Actin (SM), vimentin, cytokine (CK), epithelial membrane antigen (EMA) and Ki-67. Based on the the above clinical features、histopathology and immunohistochemical, the tumor was definitively diagnosed as bladder’s IMT. After 24 months, there was no signs of recurrence and metastasis with CT and cystoscopy.Conclusion: A rare case of inflammatory myofibroblastic tumor of urinary bladder after partial cystectomy was reported. It is essential for urologists and scientists to entirely understand the characteristics of the inflammatory myofibroblastic tumor and make a better clinical guideline, to avoid over treatments.
Genetic characterization and phylogenetic analysis of Novel Duck-Origin Goose Parvovirus in Anhui Province, Eastern China
Authors: Wang Yong , Sun Jianfei , Zhang Da , Guo Xu , Shen Wenhao , Li Yongdong 
Published: February 2021

Abstract
Recently, a novel duck-origin goose parvovirus (N-GPV) was reported to cause short beak and dwarfism syndrome in ducks. In this study, we performed complete genome sequencing and analyzed three different duck-derived parvoviruses that infected different breeds of ducks. Phylogenetic trees based on gene sequences indicated that they were classical goose parvovirus (C-GPV), Muscovy duck parvovirus (MDPV), and N-GPV, respectively. Furthermore, potential recombination events were found. These results improve our understanding of the diversity of duck-derived parvoviruses in the Anhui province, eastern China, and provide a reference for the prevention of associated diseases.
Cross-cultural Adaptation and Validation of the Lebanese Arabic version of the BACS scale (the Brief Assessment of Cognition in Schizophrenia) among stable schizophrenic inpatients
Authors: Haddad Chadia , Salameh Pascale , Hallit Souheil , Obeid Sahar , Haddad Georges , Clément Jean-Pierre , Calvet Benjamin 
Published: February 2021

Abstract
IntroductionAssessment of cognitive disorders in schizophrenia is becoming a part of clinical and research practice by using batteries that differ widely in their content. The Brief Assessment of Cognition in Schizophrenia (BACS) was developed to cover the main cognitive deficits of schizophrenia. The objective of this study was to assess concurrent validity of the Arabic version of the BACS with a standard neurocognitive battery of tests in Lebanese patients with schizophrenia and healthy controls.MethodsA sample of 120 stable inpatients diagnosed with schizophrenia and 60 healthy controls received the Arabic version of the BACS in a first session, and a standard battery in a second session. ResultsMean duration of completion for the BACS was 31.2 ± 5.4 min in patients with schizophrenia. All tests demonstrated significant differences between controls and patients (p < .01). Principal components analysis demonstrated that a one-factor solution best fits our dataset (64.8% of the variance). High Cronbach alpha was found (.85). The BACS composite scores were significantly correlated with the standard battery composite scores in patients (r = .78, p < .001) and healthy controls (r = .77, p < .001). Also, correlation analysis between the BACS sub-scores and the standard battery sub-scores showed significant results (p < .05). The Arabic-BACS demonstrated high ability to discriminate patients with schizophrenia from healthy controls.Conclusion Results showed that the Arabic version of the BACS is a useful tool for assessing cognition in patients with schizophrenia and could be used in clinical practice in Lebanon.
Improved Tunability And Energy Storage Density Properties Of Low Loss, Lead Free (Ba0.50Sr0.50)Tio3 And Ba(Zr0.15Ti0.85)O3 Bilayer Thin Film Stacks
Authors: Mahesh M.L.V. , Pal Prem , V.V. Bhanu Prasad , James A.R. 
Published: February 2021

Abstract
Multilayer thin films of (Ba0.50Sr0.50)TiO3 (BST) and Ba(Zr0.15Ti0.85)O3 (BZT) were designed and grown using Pulsed LASER Deposition technology. The periodic (BST/BZT)n thin films were deposited on Pt‹111›/SiO2/Si substrates. X-ray diﬀraction reveals the presence of a polycrystalline, perovskite structure corresponding to the bilayer thin film stacks. SEM analysis confirmed the multilayer structure without any interdiffusion across layers. It was also found that the dielectric and ferroelectric properties of the thin films are strongly influenced by the periodic hetero-structures. The thin film stacks exhibit significantly higher tunabilities, comparable with multilayer thin films grown on various single crystal substrates such as LaAlO3, MgO and SrTiO3. Possible mechanisms explaining the other observed attributes such as lower dielectric loss resulting in higher Figure of Merit (FoM), low leakage current are discussed. The effect of incorporating a comparatively lower permittivity thin film in the multilayer stacks is presented. The observed properties of such multilayer structured films help in realization of low loss and highly tunable applications.
Densification and fine grain formation mechanisms of BaTiO3 ceramics consolidated by self-assembly sintering
Authors: Jin Quan , Zhao Lili , Zhang Xiaoting , Zhang Run , Cui Bin 
Published: February 2021

Abstract
In this paper, from the perspective of thermodynamics and kinetics, we have studied the mechanism of balancing the densification and grain growth via co-sintering the micron and nano powders, also known as self-assembly sintering. In the experiment, the 200 nm and 80 nm BaTiO 3 spherical powders were used as models for combination and co-sintering. In terms of thermodynamics, the contact angle method is applied to determine the free energy of the binary particle size system. The surface free energy of 200 nm and 80 nm BaTiO 3 powders are 51.66 J/mol and 203.47 J/mol, respectively. When the powder ratio is 1:1, the surface free energy of the binary particle size system is 127.56 J/mol, which is the reason for the balance between densification and grain growth. In terms of kinetics, the Arrhenius equation was utilized to calculate the apparent activation energy ( Q ) of the binary particle size system. The results show that the value of Q is 360 kJ/mol at 1000 °C. The fine-grained ceramics with high relative density obtained by this sintering method at a low sintering temperature (1000 °C) can be explained by the relative low value of Q.
Determination of the flood volume by the aspects of peak flow and flood hydrograph at the level of the city of Biskra, Wadi Biskra watershed, Algeria.
Authors: Boumessenegh amel , dridi hadda 
Published: February 2021

Abstract
The peak flow of a flood can be determined by several empirical methods. Among these methods, the Gradex method is used in this work to estimate the project flood and the volumes corresponding to the flows. This approach has made it possible to recognize the flow of different frequencies by aspects of the peak flow and the flood hydrograph. The study was based on the maximum annual daily rainfall for a long series of observations (47 years), and on the intensity-duration-frequency (IDF) curves of the four rainfall stations Biskra, T'kout, Djemoura, and El kantara; located in the watershed of Oued Biskra. The application of the Gradex method has allowed to approach the maximum flow of floods at the level of the outlet which is located at the entrance of the city of Biskra; for the rare frequency of occurrence (return periods ranging from 10 to 1000 years).
Enhanced optical, morphological, dielectric, and conductivity properties of gold nanoparticles doped PVA/CMC blend as an application in organoelectronic devices
Authors: Atta M. R. , Alsulami Qana M. , Asnag G. M. , rajeh A . 
Published: February 2021

Abstract
Stevia rebaudiana plant leaves were used for biosynthesis of gold nanoparticles (AuNPs). Transmission electron microscope ( TEM ) images showed various shapes and sizes of AuNPs. Various amounts of AuNPs were added to polyvinyl alcohol/carboxymethylcellulose ( PVA / CMC , 40/60) via the casting method. The X-ray diffraction (XRD) spectrum of pure blend shows the amorphous nature of the blend. FT-IR spectra showed the interaction between PVA / CMC and AuNPs. The ultra-violet and visible (UV/VIS.) spectra showed emerge new peak of surface plasmon resonance ( SPR ) of AuNPs for the filled samples. SEM images showed bright spots on the sample's surface, which was attributed to AuNPs. AC conductivity exhibited enhancement after the addition of gold nanoparticles. The ε′ and ε″ were reduced with increasing the frequency due to direction dipoles of applied electric ﬁeld. Because of the mobile charges inside the polymeric backbone, higher values of ε′ and ε″ were observed at low frequencies. The tanδ showed increased with an increase in AuNPs concentration and at the decrease the frequency, as expected.
Ficus religiosa (Linn.) bark extract secondary metabolites bestow antioxidant property inducing cell cytotoxicity to human breast cancer cells, MDA-MB-231 by apoptosis involving apoptosis-related proteins, Bax, Bcl-2 and PARP
Authors: Shankar Preethi , Kuppuru Marulasiddaswamy Mallikarjunaiah , Kini Ramachandra Kukkundoor , Sekhar Shailasree 
Published: February 2021

Abstract
Ficus species, auspicious in many cultures worldwide are sources of novel bioactive secondary metabolites. The mechanism by which they exhibit antioxidant and apoptotic properties is scant. The main objective of the current study was to evaluate the properties of activity guided fractionated bark methanol extract of Ficus religiosa. As the methanol extract exhibited highest antioxidant activity it was evaluated for secondary metabolites and therapeutic properties. UPLC-MS analysis of the extract identified the 11 and five secondary metabolites including the rutin, 3-caffeoylquinic acid, luteolin 7-O-rutinoside, 6-C-glucosyl-8-C-arabinosylapigenin and kaempferol-3-O-rutinoside were reported. The MTT assay results identified minimal cytotoxicity for non-cancerous cell line (HEK 293 T) and maximum cell death for human breast cancer cells, MDA-MB-231 (EC50, 91.32 ± 4.21µ g.mL− 1). A high degree of DNA fragmentation in MDA-MB-231 cells subjected to the extract was observed. A clear indication of apoptosis via chromatin condensation was visualized by CLSM. The apoptotic response to treatment was also apparent in the increase in BAX along with the proteolytic cleavage of PARP-1 and a decreased Bcl-2 levels as revealed by Western blot analysis. The MDA-MB-231 cells upon exposure to the extract (91µ g.mL− 1), stimulated cells to early apoptosis (32.5%) and apoptosis (61.6%) as evidenced by flow cytometer studies. Apoptotic cells being represented by a sub G0/G1 population (86.25%) seen to the left of the G0/G1 peak were recorded. The presence of novel bioactive compounds has uncovered possible therapeutic values by modulating antioxidant and apoptosis leading to the development of potential alternative anticancer drugs.
An Efficient And Quick Protocol For In Vitro Multiplication Of Snake Plant, Sansevieria Trifasciata Var. Laurentii [Prain]
Authors: Kaur Jaspreet , MUDGAL GAURAV 
Published: February 2021

Abstract
An efficient protocol was developed for quick propagation of snake plant under in vitro conditions. Leaf segments were surface sterilized and inoculated on Murashige and Skoog media supplemented with 3% sucrose, 0.8% agar, and various concentrations of indole-3-butyric acid. Cultures were maintained for 4-5 weeks at standard conditions to allow root induction and elongation. Shoot induction is triggered upon altering the culture room temperature to 37±2⁰C. Multiple shoots were witnessed at higher IBA concentrations. Another 5 weeks later, individual plantlets were excised and hardened for 2 weeks in soil preparation contained in small cups before transferring to big sized pots.
Optical Coherence Encryption with Structured Random Light
Authors: Peng Demin , Huang Zhaofeng , Liu Yonglei , Chen Yahong , Wang Fei , Ponomarenko Sergey A. , Cai Yangjian 
Published: February 2021

Abstract
Information encryption with optical technologies has become increasingly important due to remarkable multidimensional capabilities of light fields. However, the optical encryption protocols proposed to date have been primarily based on the first-order field characteristics, such as the optical field amplitude and phase as well as its polarization. As the said first-order characteristics of light fields are strongly affected by interference effects, the conventional encoding protocols become quite unstable during light propagation and interaction with the matter. Here, we introduce an alternative optical encryption protocol whereby the information is encoded into the spatial coherence distribution of a structured random light beam via a generalized van Cittert--Zernike theorem. We show that the proposed approach has two key advantages over its conventional counterparts. First, the complexity of measuring the spatial coherence distribution of light enhances the encryption protocol security. Second, the relative insensitivity of the second-order statistical characteristics of light to environmental noise makes the protocol robust against the environmental fluctuations, e.g, the atmospheric turbulence. We carry out experiments to demonstrate the feasibility of the coherence-based encryption method with the aid of a fractional Fourier transform. Our results open up a promising avenue for further research into optical encryption in complex environments.
Microparticles from human lower airway showed inhibitory activity against respiratory syncytial virus
Authors: Boonarkart Chompunuch , Suptawiwat Ornpreya , Ruangrung Kanyarat , Maneechotesuwan Kittipong , Auewarakul Prasert 
Published: February 2021

Abstract
Airway microparticles (MPs) have been previously shown to inhibit influenza virus by trapping virions on their surface through surface viral receptor. It was hypothesized that airway MPs may carry most of epithelial cell surface molecules including receptors for respiratory viruses and may be able to inhibit various respiratory viruses. We show here that MPs from human bronchoalveolar lavage (BAL) could inhibit respiratory syncytial virus (RSV). Those MPs were stained positive for the RSV receptor, CX3CR1. Furthermore, incubating the MPs with a monoclonal antibody against CX3CR1 reduced the anti-RSV activity. These indicate that MPs can contribute to respiratory innate antiviral defense.
Efficacy and Safety Comparison between Drug-eluting Beads CalliSpheres and Conventional Transcatheter Arterial Chemoembolization in Treating Renal Angiomyolipoma Patients
Authors: Lyu Tianshi , Wang Jian , Tong Xiaoqiang , Mi Tianai , An Chao , Zou Yinghua 
Published: February 2021

Abstract
Background: There is a lack of evidence of standard or superior treatment among renal angiomyolipoma (RAML) patients. This study aimed to compare the short-term efficacy and safety using CalliSpheres microspheres (CSM) with conventional transcatheter arterial chemoembolization (cTACE) in treating Chinese patients with RAML. Methods: A total of 54 patients with RAML treated by TACE from February 2018 to April 2020 were retrospectively analyzed. These included 17 cases in the CSM-TACE group and 37 cases in the cTACE group. The clinical efficacy, tumor reduction rate and complications were compared between the two groups. Furthermore, blood routine indexes and kidney function test were compared between the two groups before and at the third day after the operation. Results: The embolization was performed successfully in all patients without serious adverse events and death. Except for abdominal pain (p=0.044) and white blood cell (WBC) (p=0.047), there were no significant differences in baseline characteristics (p>0.05). As for treatment efficacy, 42 patients with RAML had tumor size reduced after embolization. Compared with CSM-TACE group (0.12±0.34), tumor volume reduction rate was slightly higher in cTACE group (0.32±0.31) with p value 0.047. As for treatment safety, postoperative WBC and creatine level in two groups were both in normal range and not significantly different (p=0.114 and 0.659). Besides, no significant differences were observed in complication and length of stay after the operation between the two groups (p=0.347 and 0.593).Conclusions: CSM could be a safe and good option for embolization therapy in treating Chinese patients with RAML in clinical practices. Large cohort perspective study is still needed in the future.
Three-dimensional simulation of regional urban waterlogging based on high-precision DEM model
Authors: Chen Zipeng , Li Kun , Du Jianhua , Chen Yi , Liu Ronggang , Wang Yi 
Published: February 2021

Abstract
In order to deal with the urban waterlogging disasters, a high precision three-dimensional (3D) Digital Elevation Model (DEM) is built in this paper. This DEM is based on high-precision data of urban topography and geomorphology, covering 3D surface elevation, road network and structures. The simulation calculation of this model can get different watershed area according to different elevation based on the topographic feature. Furthermore, divide the urban regional model into the stage sub-catchment area corresponding to the elevation. Within the sub-catchment area, it can also reflect the situation of urban waterlogging, in combination with the rainstorm intensity formula, the statistics of local area underlying surface, and Soil Conservation Service (SCS) model of runoff simulation. It can also help to simulate the submergence depth and range under different recurrence stages of rainfall scenarios. The research shows that this DEM model can provide the premise for the highly accurate numerical simulation of surface runoff and confluence, which can effectively improve the accuracy of the division of catchment area and the assessment, prediction of waterlogging disaster. This provides an important idea and method for the flood prevention and control in flood season for reservoir, tailings pond and urban waterlogging.
Experiences of Ethnic Minority Patients Who Are Living with a Primary Bowel Condition or Bowel-Related Symptoms of Other Chronic Diseases: A Systematic Review
Authors: Ahmed Salina , Newton Paul D. , Ojo Omorogieva , Dibley Lesley B. 
Published: February 2021

Abstract
Background: Prevalence of chronic gastrointestinal diseases has been rising amongst ethnic minority populations in Western countries, despite the first-generation migrants originating from countries of low prevalence. Differences caused by genetic, environmental, cultural, and religious factors in each context may contribute towards shaping experiences of ethnic minority individuals living with primary bowel conditions. This review aimed to explore the experiences of ethnic minority patients’ living with chronic bowel illnesses and bowel-related symptoms of other chronic diseases. Methods: We systematically searched for qualitative, quantitative, and mixed methods studies on eight electronic databases and manually searched reference lists of frequently cited papers. Fifteen papers met the inclusion criteria: focussing on inflammatory bowel disease, irritable bowel syndrome, coeliac disease and prostate cancer survivors experiencing bowel symptoms. Results: Core themes were narratively analysed. South Asians had limited understanding of their illness and language and literacy barriers, particularly older generations, suggesting a need for culturally relevant inflammatory bowel disease and coeliac disease information. Family support was limited, and Muslim South Asians referred to religion to understand and self-manage inflammatory bowel disease. Ethnic minority groups across countries experienced poor dietary intake for coeliac disease and inflammatory bowel disease, cultural conflict in self-managing diet for inflammatory bowel disease, increased anxiety, and the need for better quality of, and access to, healthcare services. UK ethnic minorities had problems with IBD diagnosis/misdiagnosis. Self-efficacy positively impacted bowel symptoms in prostate cancer survivors. Conclusions: Cultural, religious, and social contexts, together with language barriers and limited health literacy influenced experiences of health inequalities for ethnic minorities with chronic bowel diseases.