bluuebunny/crossref_metadata_2025_split huggingface dataset:
Potensi Pati Sagu Dan Pendapatan Masyarakat Di Kampung Mega Distrik Mega Kabupaten Sorong
Authors: Nanlohy Lona Helti , Gafur Muzna Ardin 
Published: June 2021

Sagu merupakan salah satu penghasil karbihodrat, sagu dapat dimanfaatkan dalam bentuk pati yang dapat diolah menjadi berbagai produk. Pati sagu selama ini dimanfaatkan sebagai makanan pokokÂ bagi masyarakatÂ Papua terutama masyarkat yang bermukim di daerah pesisir yang umumnya dalam bentuk pangan tradisional misalnya dikonsumsikan sebagai bahan makanan pokok dalam bentuk papeda. Disamping sebagai makanan pokok sagu juga dikonsumsi sebagai makanan pendamping seperti ;Â sagu lempeng dan sagu bungkus.Tujuan dari penelitian ini adalah untuk mengetahui potensi pati sagu dan pendapatan masyarakat di Kampung Mega Distrik Mega Kabupaten Sorong. Pengukuran Potensi sagu dilakukan melalui metode survey dengan pangamatan dan pengukuran langsung di lapangan Pengukuran Potensi pati sagu dilakukan dengan pengukuran diameter pohon sagu (cm) dan tinggi pohon sagu (m) pengukuranÂ potensi pati sagu dalam penelitian ini hanya di batasi pada tumbuhan sagu fase Masak tebang (MT).Â Metode yang digunakan untuk pengukuran kerapatan pohon sagu masak tebang adalah metode jalur.Potensi pati sagu rata-rata perpohon adalah 282,93 kgÂ dengan diameter pohon sagu berkisar antara 37 sampai 57 cm dengan rata-rata 47 cm, sedangkan tinggi pohon berkisar antara 15 sanpai 28 m dengan rata-rata 19,29 m. Luas areal yang menjadi sampel penelitian adalah 5 Ha dari 100 ha luas keseluruhan hutan sagu. Ditemukan 74 pohon sagu masak tebang (MT) sehingga hasil perhitungan potensi pohon sagu masak tebang (MT) adalah 14.8 pohon/Ha. Pendapatan masyarakat Â adalah sebesar Rp. 31.410.000/bulan atau rata-rata Rp. 1.847.647/bulan.
Pengamatan Jenis Predator Hama Tanaman Padi Di Kampung Karya Bumi Distrik Waibu Kabupaten Jayapura
Authors: Lawalata Jacob Julius , Anam Khairul 
Published: June 2021

Musuh alami (parasitoid dan predator) pada hakekatnyaÂ secara alami dapat mengedalikan hama-hama yang menyerang tanaman padi pada semua tingkatan umur ketika lingkungan sekitarnya mendukung untuk perkembangbiakan musuh alami tersebut. Hal tersebut dimungkinkan karena ekosistem pertanian di Indonesia yang beriklim tropis ini sangat memungkinkan berkembangnya berbagai jenis musuh alami yang secara efektif dapat mengendalikan atau menekan populasi dari pada hama namun karena cara pengelolaan pertanian yang tidak tepat serta tidak berwawasan lingkungan seperti penggunaan pestisida secara tidak tertanggungjawab dapat menyebabkan terbunuhnya musuh-musuh alami yang ada. Tujuan dari pada penelitian ini adalah untuk mengetahui jenis â€“ jenis predator hama tanaman padi di Kampung Karya Bumi Distrik Namblong Kabupaten Jayapura. Penelitian iniÂ Â Â dilaksanakan di Kampung Karya Bumi Distrik Namblong Kampung Karya Bumi Distrik Namblong Kabupaten Jayapura dari bulan November - Desember 2017 dengan menggunakan metode survey dengan teknik pengumpulan data melalui observasi , wawancara dan studi pustaka. Hasil pengamatan musuh alami (predator) di Desa Karya Bumi Distrik Namblong Kabupaten Jayapura ditemukan tiga (3) jenis predator yaitu (1) Laba-Laba Pemburu (Lycosa sp), (2) Kepending Air (Microvelia douglasiÂ atrolineata Berqroth
Jumlah Total Mikroba Susu Kedelai (Glycine max) Dengan Penambahan Sari Jahe Merah Selama Penyimpanan
Authors: Maitimu Centhya Victorin , Wattimena Lanny 
Published: June 2021

Susu kedelai merupakan minuman kesehatan bernilai gizi tinggi dengan kandungan protein utama yang terdapat didalamnya. Susu kedelai segar telah diproduksi masyarakat Desa Layeni Kabupaten Maluku Tengah sejak lama dengan menggunakan teknik produksi secara konvensional. Walaupun memiliki cita rasa yang tidak berbeda dengan produk olahan pabrik, akan tetapi produk susu kedelai yang diproduksi masyarakat Desa Layani rentan terkontaminasi mikroba karena proses pengolahannya kurang steril dan tidak menggunakan pengawet buatan dalam pengolahannya. Dengan cara konvensional masyarakat Desa Layeni mendayagunakan zat tambahan alami berupa jahe merah yang diekstrak untuk meningkatkan daya simpan susu kedelai sekaligus berfungsi sebagai zat anti mikroba guna menekan laju pertumbuhan mikroba. Tujuan penelitian ini adalah untuk mengetahui jumlah total mikroba susu kedelai (Glycine max) hasil olahan masyarakat Desa Layeni Kecamatan Teon Nila Serua Kabupaten Maluku Tengah dengan penambahan sari jahe merah (zingiber officinale var. rubrum) selama penyimpanan. Jenis penelitian yang digunakan adalah penelitian eksperimen laboratorium, dengan tingkatan konsentrasi sari jahe merahÂ yaitu 0%, 0,5%, 1% dan 1,5%. Hasil penelitian menunjukkan bahwa jumlah total mikroba susu kedelai terendah terdapat pada kosentrasi 1,5% Â tanpa penyimpanan (0 jam) yaitu (3,4 x 104 koloni/ml) sedangkan jumlah total mikroba tertinggi terdapat pada konsentrasi sari jahe merah 0% penyimpanan 24 jam yaitu (9,5 x 107 koloni/ml). Menurut Standard Nasional Indonesia (SNI) No.06.8-7388-2009 persyaratan cemaran mikroba pada produk sari kedelai yaitu mengandung total mikroba maksimal 5x104 koloni/ml, maka dapat disimpulkan bahwaÂ penambahan kosentrasi 1,5% sari jahe merah (Zingiber officinale var. Rubrum) dapat meningkatkan daya simpan susu kedelai selama 6 jam dengan total mikroba 4,3 x 104 koloni/ml.
Analisis Kemampuan Lahan dan Kesuburan Tanah Pada Lahan Perencanaan Kebun Percobaan Universitas Muhammadiyah Sorong di Kelurahan Sawagumu Kecamatan Malaimsimsa
Authors: Fajeriana M Nurul , Wijaya Ranti 
Published: June 2021

Â Kebun percobaan merupakan salah satu unsur penunjang utama dalam kegiatan akademik pada Universitas Muhammadiyah Sorong. Tidak hanya peruntukannya untuk dosen tetapi juga untuk mahasiswa dalam melakukan praktikum, penelitian, pengkajian maupun pengembangan pertanian yang ada. Kebun percobaan pada fungsinya harus mendukung segala bentuk aktifitas dalam bidang akademik, terkhusus dalam ilmu pertanian. Dalam hal ini karakteristik lahan dan juga status hara sangat penting untuk dikaji sehingga diperoleh kebijakan dalam arah pemanfaatan lahan. Penelitian ini dilakukan selama 7 bulan yang berlangsung dari bulan April hingga Oktober 2020 dengan metode survey dan pengambil sampel tanah secara Simple Random Sampling di lahan perencanaan Kebun Percobaan Universitas Muhamadiyah Sorong di Jl. Arteri Kelurahan Malaingkeidi, Kecamatan Sawagumu Kota Sorong dan olah data kesuburan tanah berdasarkan analisis kimia tanah dari Laboratorium Kimia dan Kesuburan Tanah, Departemen Ilmu Tanah, Fakultas Pertanian, Universitas Hasanuddin. Dari hasil status hara memiliki unsur hara untuk pertumbuhan tanaman sangat rendah hingga sedang. Dan untuk Kelas Kemampuan Lahan masuk dalam kelas V dengan faktor pembatas genangan, iklim dan darinase tanah. Oleh karena itu diberikan rekomendasi perbaikan yakni dengan pembajakan dan perataan tanah, pembuatan gundukan atau bedengan serta penutupan tanah dengan bahan organik. Hal ini dimaksudkan agar dapat memaksimalkan penggunaan lahan untuk peruntukan pertanian yang lestari.
Keberlanjutan Agroindustri Pala Fakfak : a Sistematic Literature Review (SLR)
Authors: Waromi Josina 
Published: June 2021

Salah satu tanaman perkebunan yang menjadi komoditi unggulan Provinsi Papua Barat adalah adalah tanaman pala yang dominan tumbuh di Kabupaten Fakfak. Potensi pengembangan pala Fakfak menjadi produk agroindustry yang bernilai jual tinggi dan keberlanjutannya menjadi hal yang penting. Oleh karena itu penelitian ini bertujuan mengkaji keberlanjutan agroindustry pala Fakfak berdasarkan empat indikator yaitu ketersediaan bahan baku pala Fakfak, perubahan preferensi konsumen terhadap produk turunan pala Fakfak, karakteristik pesaing dalam agroindustry pala Fakfak dan sumberdaya manusia yang mengolah pala Fakfak. Metode yang digunakan adalah Systematic Literature Review dengan PRISMA (Preferred Reporting items for Sistematic Review and Meta-Analysis). Hasil kajian menunjukkan bahwa dari 213 jurnal yang diunduh terdapat 17 jurnal yang meneliti tentang pala Fakfak, namun dari 17 jurnal tersebut yang memenuhi kriteria Inklusi dan Ekskluis hanya 9 jurnal. Berdasarkan 9 jurnal tersebut, menjelaskan bahwa ketersediaan Pala Fakfak sebagai bahan baku untuk kegiatan agroindustry cukup tersedia, sedangkan preferensi konsumen masih rendah dikarenakan konsistensi dalam rasa dan kemasan. Terkait pesaing dan sumberdaya manusia, diperoleh informasi bahwa pesaing dalam perdagangan buah pala berada dalam pasar Oligopsoni sedangkan pesaing produk olahan dari kegiatan agroindustry terjadi dalam pasar persaingan sempurna. Mengenai sumberdaya manusia masih perlu ditingkatkan dalam penggunaan teknologi dan managemen.Â Dengan demikian terkait keberlanjutan agroindustry hanya ketersediaan bahan baku yang dapat mendorong terjadi keberlanjutan agroindustry Pala Fakfak.
Analisis Respon Masyarakat Terhadap Dampak Aktivitas Penambangan Pasir Dan Batu Di Sungai Berni Desa Sumberasri kecamatan Nglegok Kabupaten Blitar
Authors: Pingki Tamara 
Published: June 2021

ABSTRACTSand and stone mining activities along the Berni River in Sumberasri Village, Nglegok District, Blitar Regency are still ongoing, so that the impact on the community is increasingly being felt. The real impact felt by the community is landslides and erosion. The purpose of this study was to analyze the community's response to the impact of sand and rock mining activities in the Berni River, Sumberasri Village, Nglegok District, Blitar Regency. The method used is a survey by conducting interviews with 40 residents who live around the Berni River, Sumberasri Village, Nglegok District, Blitar Regency. Based on the data analysis that has been carried out and explained, most of the people living around the mining area are not disturbed by mining activities because sand and rock mining is their main livelihood. There are 80% of people living in mining areas who admit that mining activities do not interfere with their activities, 90% of people who live in mining areas admit that their health is not disturbed, and 80% of people who live in mining areas admit that they have benefited from sand and rock mining activities. the. However, they all realized that the mining of sand and rock was causing losses, namely that more roads were damaged and erosion and landslides were frequent.Â Keywords: Mine, Sand and Stone.Â ABSTRAKAktivitas penambangan pasir dan batu di sepanjang Sungai Berni di Desa Sumberasri, Kecamatan Nglegok, Kabupaten Blitar masih berlangsung sampai saat ini, sehingga dampak di masyarakat semakin dirasakan. Dampak nyata yang dirasakan masyarakat adalah longsor dan erosi. Tujuan dari penelitian ini adalah untuk menganalisis respon masyarakat terhadap dampak aktivitas penambangan pasir dan batu di Sungai Berni, Desa Sumberasri, Kecamatan Nglegok, Kabupaten Blitar. Metode yang digunakan adalah survei dengan melakukan wawancara terhadap 40 warga yang tinggal di sekitar Sungai Berni, Desa Sumberasri, Kecamatan Nglegok, Kabupaten Blitar. Berdasarkan analisis data yang telah dilakukan dan dijelaskan, sebagian besar masyarakat yang tinggal di sekitar area pertambangan tidak mendapat gangguan akibat aktivitas penambangan karena penambangan pasir dan batu tersebut merupakan mata pencaharian utama mereka. Terdapat 80% masyarakat yang tinggal di area pertambangan mengakui bahwa aktivitas penambangan tidak mengganggu aktivitas mereka, 90% masyarakat yang tinggal di area pertambangan mengakui bahwa kesehatan tidak terganggu, dan 80% masyarakat yang tinggal di area pertambangan mengaku mendapat manfaat dari kegiatan penambangan pasir dan batu tersebut. Namun, mereka semua menyadari bahwa penambangan pasir dan batu tersebut menyebabkan kerugian, yaitu semakin banyak jalan yang rusak serta sering terjadi erosi dan longsor.Â Kata kunci: Tambang, Pasir dan Batu.
Estimation of Reaction Rates of Transesterification Pathways
Authors: Pérez-Méndez Mario Alberto , Jiménez-García Gladys , Huirache-Acuña Rafael , Maya-Yescas Rafael 
Published: June 2021

Experimental estimation of reaction rates is a common aspect of reaction engineering because reaction kinetics are the base of the design of chemical reactors. However, it is not easy to follow complex reactions as it is the case of transesterification of triglycerides in presence of sodium hydroxide. Identifying the possible reaction pathways taking place as ionic and sequential, starting with the inorganic formation of methoxide, and followed by each one of the three organic transesterification steps of virgin soybean oil, deeper understanding about kinetics of this reacting path has been obtained. Reaction rate evaluations were performed by following the solution’s pH, based on a 24–1 design of experiments, making possible to estimate the rate constants. Additionally, it was observed that there is an optimum amount of sodium hydroxide feed to the process, therefore it is possible to minimize its addition, which favors diminishing the volume of leaching water. The best yield to fatty acid methyl esters, using the minimum amount of sodium hydroxide, was 98.84 wt%, which is highly competitive.
Context-Responsive Anticoagulation Reduces Complications in Pediatric Extracorporeal Membrane Oxygenation
Authors: Lin John C. , Barron Lauren M. , Vogel Adam M. , Colvin Ryan M. , Baltagi Sirine A. , Doctor Allan , Gazit Avihu Z. , Mehegan Mary , O'Connor Nicole , Said Ahmed S. , Shepard Mark , Wallendorf Michael , Spinella Philip C. 
Published: June 2021

Purpose: We sought to determine the impact of a comprehensive, context-responsive anticoagulation and transfusion guideline on bleeding and thrombotic complication rates and blood product utilization during extracorporeal membrane oxygenation (ECMO).Design: Single-center, observational pre- and post-implementation cohort study.Setting: Academic pediatric hospital.Patients: Patients in the PICU, CICU, and NICU receiving ECMO support.Interventions: Program-wide implementation of a context-responsive anticoagulation and transfusion guideline.Measurements: Pre-implementation subjects consisted of all patients receiving ECMO between January 1 and December 31, 2012, and underwent retrospective chart review. Post-implementation subjects consisted of all ECMO patients between September 1, 2013, and December 31, 2014, and underwent prospective data collection. Data collection included standard demographic and admission data, ECMO technical specifications, non-ECMO therapies, coagulation parameters, and blood product administration. A novel grading scale was used to define hemorrhagic complications (major, intermediate, and minor) and major thromboembolic complications.Main Results: Seventy-six ECMO patients were identified: 31 during the pre-implementation period and 45 in the post-implementation period. The overall observed mortality was 33% with no difference between groups. Compared to pre-implementation, the post-implementation group experienced fewer major hemorrhagic and major thrombotic complications and less severe hemorrhagic complications and received less RBC transfusion volume per kg.Conclusions: Use of a context-responsive anticoagulation and transfusion guideline was associated with a reduction in hemorrhagic and thrombotic complications and reduced RBC transfusion requirements. Further evaluation of guideline content, compliance, performance, and sustainability is needed.
Sex-Specific Association of Left Ventricular Hypertrophy With Rheumatoid Arthritis
Authors: Giollo Alessandro , Cioffi Giovanni , Ognibeni Federica , Bixio Riccardo , Fassio Angelo , Adami Giovanni , Orsolini Giovanni , Dalbeni Andrea , Idolazzi Luca , Gatti Davide , Rossini Maurizio , Viapiana Ombretta 
Published: June 2021

Objectives: Clinical expression of rheumatoid arthritis (RA) varies by gender, but whether cardiovascular disease (CVD) is gender related in RA is unknown. Left ventricular (LV) hypertrophy (LVH) is a hallmark of CVD in RA patients. We investigated whether the association of LVH with RA is gender driven.Methods: Consecutive outpatients with established RA underwent echocardiography with measurement of LVH at baseline and one follow-up. All participants had no prior history of CVD or diabetes mellitus. We assessed CVD risk factors associated with LVH at follow-up, including sex, age, arterial blood pressure, and body mass index (BMI). We also evaluated inflammatory markers, autoimmunity, disease activity, and the use of RA medications as predictors of LVH.Results: We recruited 145 RA patients (121 females, 83%) and reassessed them after a median (interquartile range) of 36 months (24–50). At baseline, women were more dyslipidemic but otherwise had fewer CVD risk factors than men, including less prevalent smoking habit and hypertension, and smaller waist circumference. At follow-up, we detected LVH in 42/145 (44%) RA patients. LV mass significantly increased only in women. In multiple Cox regression analysis, women with RA had the strongest association with LVH, independently from the presence of CVD risk factors (OR, 6.56; 95% CI, 1.34–30.96) or RA-specific characteristics (OR, 5.14; 95% CI, 1.24–21.34). BMI was also significantly and independently associated with LVH.Conclusion: Among established RA patients, women carry the highest predisposition for LVH.
Rheumatic Myocarditis: A Poorly Recognized Etiology of Left Ventricular Dysfunction in Valvular Heart Disease Patients
Authors: Rosa Vitor Emer Egypto , Lopes Mariana Pezzute , Spina Guilherme Sobreira , Soares Junior Jose , Salazar David , Romero Cristhian Espinoza , Lottenberg Marcos Pita , de Santis Antonio , Pires Lucas José Neves Tachotti , Gonçalves Luis Fernando Tonello , Fernandes Joao Ricardo Cordeiro , Sampaio Roney Orismar , Tarasoutchi Flavio 
Published: June 2021

Background: Heart failure occurs in ~10% of patients with acute rheumatic fever (RF), and several studies have shown that cardiac decompensation in RF results primarily from valvular disease and is not due to primary myocarditis. However, the literature on this topic is scarce, and a recent case series has shown that recurrent RF can cause ventricular dysfunction even in the absence of valvular heart disease.Methods: The present study evaluated the clinical, laboratory and imaging characteristics of 25 consecutive patients with a clinical diagnosis of myocarditis confirmed by 18F-FDG PET/CT or gallium-67 cardiac scintigraphy and RF reactivation according to the revised Jones Criteria. Patients underwent three sequential echocardiograms at (1) baseline, (2) during myocarditis and (3) post corticosteroid treatment. Patients were divided according to the presence (Group 1) or absence (Group 2) of reduced left ventricular ejection fraction (LVEF) during myocarditis episodes.Results: The median age was 42 (17–51) years, 64% of patients were older than 40 years, and 64% were women. Between Group 1 (n = 16) and in Group 2 (n = 9), there were no demographic, echocardiographic or laboratory differences except for NYHA III/IV heart failure (Group 1: 100.0% vs. Group 2: 50.0%; p = 0.012) and LVEF (30 [25–37] vs. 56 [49–62]%, respectively; p &lt; 0.001), as expected. Group 1 patients showed a significant reduction in LVEF during carditis with further improvement after treatment. There was no correlation between LVEF and valvular dysfunction during myocarditis. Among all patients, 19 (76%) underwent 18F-FDG PET/CT, with a positive scan in 68.4%, and 21 (84%) underwent gallium-67 cardiac scintigraphy, with positive uptake in 95.2%, there was no difference between these groups.Conclusion: Myocarditis due to rheumatic fever reactivation can cause left ventricular dysfunction despite valvular disease, and it is reversible after corticosteroid treatment.
Laparoscopic Radical Hysterectomy Results in Higher Recurrence Rate Versus Open Abdominal Surgery for Stage IB1 Cervical Cancer Patients With Tumor Size Less Than 2 Centimeter: A Retrospective Propensity Score-Matched Study
Authors: Chen Xiaoyue , Yu Jiangtao , Zhao Hongqin , Hu Yan , Zhu Haiyan 
Published: June 2021

ObjectiveTo compare the oncologic outcomes between laparoscopic and open radical hysterectomy in patients with stage IB1 cervical cancer lesion less than 2 cm.MethodsPatients diagnosed FIGO (2009) stage IB1 (tumor diameter &lt;2 cm) and underwent radical hysterectomy in our hospital between March 2008 and November 2018 were studied. A propensity-matched comparison (1:2) was conducted to minimize selection biases. Demographic and baseline oncologic characteristics were balanced between groups. Overall survival (OS) and disease-free survival (DFS) were assessed using the Kaplan–Meier model, along with univariable and multivariable regression analysis.ResultsA total of 261 patients were enrolled in this study after propensity-matching, with 174 in the open group and 87 in the laparoscopic group. Disease relapsed in seven patients in laparoscopy group, and the recurrence rate was 8.0% (7/87). There were eight patients underwent abdominal radical hysterectomy experienced recurrence, and the recurrence rate was 4.6% (8/174). The multivariate analysis model revealed that laparoscopic operation was associated with higher risk of recurrence than abdominal radical hysterectomy (HR, 3.789; 95% CI, 1.143–12.559; p = 0.029). There were five patients or 2.9% (5/174) died in open surgery group and the corresponding percentage in laparoscopy group was 2.3% (2/87). No difference was found in OS between the two groups (HR, 1.823; 95% CI, 0.2673–12.44; log-rank p = 0.5398). All the recurrence occurred within two years after operation in the laparoscopy group, among which pelvic recurrence (85.7%) was dominant.ConclusionTraditional laparotomy radical hysterectomy has a lower recurrence rate when compared with laparoscopic operation in those cervical cancer patients with a foci diameter less than 2 cm. However, no detrimental effect on survival was found in minimal invasive operation group. Further multi-center prospective trials are needed to confirm our results on a large scale.
Survival in Patients With Metastatic Prostate Cancer Undergoing Radiotherapy: The Importance of Prostate-Specific Antigen-Based Stratification
Authors: Tian Zijian , Meng Lingfeng , Wang Xin , Wang Xuan , Ma Tianming , Wang Miao , Zhong Qiuzi , Zhang Yaqun , Liu Ming 
Published: June 2021

ObjectivesTo explore the effectiveness of radiotherapy in mPCa patients with different PSA stratifications based on the cancer database of a large population.BackgroundScreening criteria for patients with metastatic prostate cancer, who are candidates for radiotherapy, are rarely reported.Patients and MethodsWe identified 22,604 patients with metastatic prostate cancer in the Surveillance, Epidemiology, and End Results database and divided them into a radiotherapy group and a control group. Patients with metastatic prostate cancer were divided into subgroups according to their levels of prostate-specific antigen to evaluate the efficacy of radiotherapy. They were also divided into six subgroups according to their prostate-specific antigen levels. We used multivariate Cox analysis to evaluate overall survival and cancer-specific survival. After 1:1 propensity score matching, Kaplan-Meier analysis was used to explore the difference in overall survival and cancer-specific survival in the radiotherapy and control group.ResultsIn all, 5,505 patients received radiotherapy, compared to 17,099 in the control group. In the multivariate Cox analysis, radiotherapy improved overall survival (hazard ratio [HR]: 0.730, 95% confidence interval [CI]: 0.636–0.838; P&lt;0.001) and cancer-specific survival (HR: 0.764, 95% CI: 0.647–0.903; P=0.002) in patients with a PSA level of 4–10 ng/mL. Similar results were obtained by Kaplan-Meier analysis after 1:1 propensity score matching. In patients with prostate-specific antigen levels between 4–10 ng/mL, the overall survival (P&lt;0.001) and cancer-specific survival (P&lt;0.05) in the radiotherapy group was significantly better than those in the control group.ConclusionThe result of this large population-based study shows that rigorous selection of appropriate metastatic prostate cancer patients for radiotherapy can benefit prognosis significantly. This can be the basis for future prospective trials.