bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of lifestyle assessment: A Delphi survey of multi-faceted health experts
Authors: Kim Ah-Ram , Lim Young-Myoung , Park Ji-Hyuk 
Published: February 2025

Objective
In the field of health promotion, there’s a growing focus on adopting an academic approach to assess and evaluate the intricate and ever-evolving nature of lifestyles. This approach is crucial for shaping and improving a healthy way of life. Systematic measurement of lifestyles is essential for enhancing overall health and well-being, encompassing physical, mental, and social dimensions. This study’s goal is to create an assessment tool that measures the diversity and intensity of lifestyle behaviors linked to human health. Our efforts involved developing quantitative measurement items that encompass the holistic concepts of health and lifestyle and validating them.

Methods
Between March and April 2023, we gathered insights from 14 experts in lifestyle and health. Building on previous research, we conducted a Delphi survey twice. In the initial survey, we collected expert opinions through open and closed-ended questions about lifestyle evaluation items. After the first survey, we corrected several items that didn’t meet the Content Validity Ratio (CVR) standard before proceeding. We presented the first survey’s findings to an expert panel, leading to a consensus.

Results
The initial Delphi round produced 76 items, and the second round resulted in 72 items after adjusting those with CVR scores of 0.51 or less. The final Content Validity Ratio was 0.83, signifying a robust validation process, with a convergence of 0.50 and a consensus level of 0.75.

Conclusion
In summary, this study successfully developed a comprehensive lifestyle assessment tool using a modified Delphi technique. The 72 items are categorized into eight subcategories and four overarching themes. This tool provides a systematic approach to evaluate lifestyles, promoting health and well-being across physical, mental, and social dimensions. It also assists in identifying specific lifestyle elements that require more in-depth intervention strategies, all while preserving the academic integrity of the content.
Unveiling parents’ lived experience with preterm infant care and support in neonatal care units of public hospitals in Nepal: A phenomenological inquiry
Authors: Shrestha Tumla , Pandey Bista Archana , Joshi Pradhan Sarala , Pudasainee-Kapri Sangita , Subedi Madhusudan 
Published: February 2025

Background
Preterm infants (PTIs) require hospitalization in different levels of neonatal care units (NCUs) for their survival and developmental needs. The quality of care provided at NCUs significantly influences infant outcomes and parents’ experiences. Parents’ experience of received support and care of PTIs is one of the indicators for determining the quality of care at NCUs. The study aims to investigate parents’ perspectives on the PTIs care and support received from nurses in NCUs of Nepal.

Methods
A descriptive phenomenological study was conducted within the NCUs of three public tertiary hospitals in Kathmandu, Nepal. In-depth interviews were conducted among 25 purposively selected parents, (both mothers and fathers) of low-birthweight PTIs admitted to the NCUs. Data was collected from November 2019 to February 2020. The data were meticulously analyzed using the Colaizzi method.

Findings
The exploration of parents’ experiences identified three main theme areas: (1) Care and support, (2) Initial involvement in PTI care, and (3) Outcome of care involvement. Parents appreciated competent and affectionate PTI care as well as informational support. However, they had varied experiences with communication, emotional support, and opportunities for infant-parent attachment. Guidance and support for PTI care from nurses and peer-parents proved instrumental in mitigating uncertainties related to initial care learning and involvement in PTI care. Parents’ involvement in hands on care of their PTIs boosted infant-parent attachment, empowered for care giving, and provided emotional solace.

Conclusion
Findings indicate that parents have positive experience with PTI care provided by nurses and their involvement in hands-on care of their PTIs. However, there are gaps in support expectations of parents including communication, emotional support, and care guidance. Findings have important implications for nurses, pediatricians, and policymakers for the enhancement of neonatal care practice by incorporating parental support and parents’ involvement in hands on care of PTI across NCUs in Nepal.
Aging increases UT‐B urea transporter protein abundance in brains of male mice
Authors: Pinki Farhana , McKeever Lauren , Costello Derek A. , Stewart Gavin 
Published: February 2025

AbstractFacilitative UT‐B urea transporters in the brain play an important role in regulating levels of urea in various cell types, including astrocytes. Numerous studies have reported increased UT‐B RNA expression with aging and in neurological disorders, such as Alzheimer's Disease. However, much less is known about the effects of these conditions on UT‐B transporter protein abundance. This current study compared the levels of UT‐B RNA and protein in young and aged male C57BL/6 mice. Endpoint RT‐PCR experiments showed UT‐B RNA expression increased in both aged cortex and aged hippocampus. Importantly, these changes were coupled with an increase in protein abundance, as western blotting revealed that 30–35 kDa UT‐B1 protein was significantly increased in aged mouse brain tissues compared with tissue from young animals. An increased UT‐B1 protein abundance was observed in the hippocampus, cerebellum, frontal cortex, and occipital cortex. In contrast, no such changes were observed in the abundance of MCT1 short‐chain fatty acid transporters in these aged tissues. These data therefore confirmed that specific increases in UT‐B1 protein abundance occur in multiple regions of the aged male mouse brain. Further studies are now needed to determine cell‐specific changes and the functional consequence of increased UT‐B1 protein in aged brain tissues.
Phytochemical analysis of Stachys iva: Discovering the optimal extract conditions and its bioactive compounds
Authors: Vantsioti Aikaterina , Makrygiannis Ioannis , Athanasiadis Vassilis , Lalas Stavros I. , Mitlianga Paraskevi 
Published: February 2025

Abstract
The Lamiaceae family is one of the widest plant families among Greek flora, consisting of a great variety of species, with the genus Stachys being one of its largest representatives, spread to most continents. The genus Stachys is also known for its beneficial properties and has been used for years as a traditional remedy for healing various health conditions. Stachys iva, an endemic plant in the Kozani Regional unit, has also been consumed as an infusion by locals and is reported to relieve common cold symptoms, have antimicrobial properties, and contribute to normalizing blood glucose levels. The present study aimed to identify the chemical compounds (such as phenolic acids, flavonoids, and phenylethanoid glycosides) responsible for the herb’s pharmacological properties and determine the optimal extraction conditions to gather an extract with high therapeutic value without solvent and energy waste. Experiments conducted proved that extracting by simple stirring with deionized water for 75 min at 80°C is the best option. In contrast, the extract’s total polyphenol content was determined, and the compounds were identified by high-performance liquid chromatography analysis. In addition, other methods were utilized (e.g., ferric-reducing antioxidant power assay and 2,2-diphenyl-1-picrylhydrazyl antiradical activity assay) to reveal potent antioxidant, anti-hydrogen peroxide, and anti-inflammatory activity, while the correlation between these properties and extraction conditions was also examined.
Diagnostic accuracy of non-mydriatic fundus photography as a triage and telemedicine tool for patients with vision loss
Authors: Ukagwu Chijindu A. , Teichman Joshua C. , Rai Amandeep S. , Rai Amrit S. , Yau Gary L. , Khan Michelle , Sharma Rahul A. 
Published: February 2025

Abstract

Objectives
Fundoscopy can be challenging for non-ophthalmologists. For emergency physicians, non-mydriatic fundus photography is superior to other forms of ophthalmoscopy in sensitivity, specificity, and inter-examination agreement. We report on a prospective cross-sectional study evaluating the use of non-mydriatic photography as a triage and telemedicine tool for patients with vision loss in a Canadian emergency setting.

Methods
Images of both eyes were obtained by a non-ophthalmologist using a handheld, non-mydriatic fundus camera and shared with a fellowship-trained ophthalmologist without patient context. The reviewer was asked to (1) select the best photo obtained for each eye and rate image quality on a Likert scale, (2) comment on the presence or absence of fundus abnormalities and (3) provide an opinion on whether findings would have changed patient disposition if available at the time of the initial Emergency Department (ED) exam.

Results
Of 57 patients evaluated in the ED for vision loss, 22.8 % had a documented fundus examination. 86.8 % of images were deemed to have acceptable quality (Likert scale≥2). Factors limiting image quality included media opacity, pupillary miosis, photosensitivity, and eyelid/periorbital abnormalities. Of patients with relevant abnormalities, 0 % were identified by emergency physicians. In contrast, 37.5 % of patients with relevant findings were identified on review of images alone (specificity=100 %).

Conclusions
Fundoscopy is infrequently performed in the emergency setting in patients presenting with vision loss. Non-mydriatic fundus photography is a cost-effective method of fundus examination for non-expert examiners and can be reliably used as a telemedicine tool for remote ophthalmology consultation.
Monetary Policy Transmission, Central Bank Digital Currency, and Bank Market Power
Authors: Chen Hanfeng , Hänsel Matthias , Nguyen Hiep 
Published: February 2025

Abstract
Interest rates on new central bank digital currencies (CBDCs) can be expected to enter the monetary policy toolkit soon. Using an extended Sidrauski (1967) model featuring an oligopsonistic banking sector, we study the complex transmission of interest rates on CBDC, which generally involve both direct and indirect effects. This is because a CBDC rate cut does not only affect the rate on the CBDC itself, but also induces the non-competitive deposit providers to adjust their spreads, as the new substitute for their products becomes relatively less attractive. A calibration exercise suggests that the indirect effects depend strongly on the sources of deposit market power: If driven by high concentration, they substantially amplify the aggregate effects of the CBDC policy rate, both in response to transitory shocks as well as regarding its long-run welfare effects. This contrasts them with policies directed at the banking sector which are weakened by a less competitive deposit market.
Analytical and numerical solution via group theoretic method for magnetogasdynamics shock wave under monochromatic radiation in non-ideal self-gravitating gas
Authors: Nath Gorakh , Upadhyay Prakash 
Published: February 2025

Abstract
The shock propagation in non-ideal self-gravitating gas with the azimuthal magnetic field and the monochromatic radiation effect have been investigated utilizing the Lie group theoretic method. The gas is assumed to be at rest having constant initial density and the magnetic fields in front of the shock front are assumed to be varying with time. For this problem, we obtained analytical and numerical solutions for the different classes of infinitesimal generators. The impacts of varying the strength of the magnetic field, gravitational parameter, parameter of non-idealness, and adiabatic exponent of the gas on the flow variable in the flow field region behind the shock, and on the moving shock with an exponential shock path have been studied in detail. The software package “Mathematica” has been used for numerical computation to obtain a similarity solution. It has been shown that the presence of magnetic field, non-idealness of the gas, and adiabatic exponent of the gas have decaying effect on the shock wave, but in the presence of the gravitation the shock strength is enhanced. The entire energy of the disturbance is not constant is not constant and varies with some power of the shock radius in the flow field behind the shock wave.
Evinacumab as an adjunct to lipid apheresis in an infant with homozygous familial hypercholesterolemia
Authors: Stirnkorb Christian , Ney Verena , Bergmann Carsten , Bald Martin 
Published: February 2025

Abstract

Objectives
Investigation of the efficacy of the angiopoietin-like protein 3 (ANGPTL3) antibody evinacumab in a four-year-old infant with homozygous familial hypercholesterolemia (HoFH) as an adjunct to lipid apheresis.

Case presentation
A two-year-old boy was found to have xanthomas of the Achilles tendon and LDL cholesterol levels around 900 mg/dL. HoHF was subsequently confirmed by molecular genetics. At the age of three, lipid apheresis was started twice a week. At the age of four, a four-weekly infusion of evinacumab was started. This resulted in a 67 % reduction in LDL cholesterol before apheresis, allowing the frequency of apheresis to be reduced to once a week. The mean LDL concentration fell by a further 37 % despite the reduction in apheresis. With the addition of ezetimibe, the mean LDL concentration was reduced to below 115 mg/dL.

Conclusions
The administration of evinacumab can significantly lower the concentration of LDL cholesterol in infants and thus reduce the frequency of lipid apheresis.
Diabetes distress, depression, and future glycemic control among adolescents with type 1 diabetes
Authors: Damilano Cecilia P. , Hong K. Ming Chan , Glick Bethany A. , Kamboj Manmohan K. , Hoffman Robert P. 
Published: February 2025

Abstract

Objectives
Increased diabetes distress and depression in adolescents with type 1 diabetes (T1D) are associated with poor glycemic control but it is not known whether they predict future glycemic control.

Methods
Patient Health Questionnaire (PHQ-9) and Problem Areas in Diabetes–Teen version (PAID-T) scores were given to 275 adolescents (age 13–17 years) with T1D. Robust rank order multivariate regression analysis was used to assess how age, duration of diabetes diagnosis, HbA1C at screen, PHQ-9 score, PAID-T screen, and insurance status predicted HbA1C at 1, 2, and 3 years after, and the changes in HbA1C over time.

Results
HbA1c and changes in HbA1c after one year were related to baseline HbA1c. At 2 and 3 years HbA1c was related to the initial HbA1C [β: 0.64 (95 % CI 0.53–0.75) and β: 0.47 (95 % CI 0.33–0.61), respectively], and to PHQ9 at screening [β: 0.07 (95 % CI 0.01–0.14) and β: 0.11 (95% CI 0.03–0.18), respectively]. Relationships were also demonstrated between PHQ9 and changes HbA1c after 2 and 3 years [β: 0.07 (95% CI 0.01–0.14) and β: 0.11 (95 % CI 0.03–0.18), respectively]. PAID-T score was not related to future glycemic control or changes in glycemic control at any time. Insurance status (private 1, public 2) also predicted future glycemic control and changes in HbA1C at 1, 2, and 3 years too.

Conclusions
Higher PHQ9 scores and public insurance predict worsening glycemic control over 3 years in adolescents with T1D while increased diabetes distress does not.
Statistical inference and data analysis of the record-based transmuted Burr X model
Authors: Alrweili Hleil 
Published: February 2025

Abstract
Probability distribution has proven its usefulness in almost every discipline of human endeavors. A novel extension of Bur X distribution is developed in this study employing the record-based transmuted mapping technique, which can be used to fit skewed and complex data. We referred to this novel distribution as a record-based transmuted Burr X model. We established the shape of the probability density function and hazard function. Numerous statistical and mathematical properties are provided, including quantile function, moment, and ordered statistics of the proposed model. Further, we obtain the estimation of the model parameters using the maximum likelihood estimation method, and four sets of Monte Carlo simulation studies are carried out to evaluate the efficiency of these estimates. Finally, the practical applicability of the developed model is demonstrated by analyzing three data sets, comparing its performance with several well-known distributions. The results highlight the flexibility and accuracy of the model, establishing it as a powerful and reliable tool for advanced statistical modeling in environmental and survival research.
Improving quantum metrology protocols with programmable photonic circuits
Authors: de las Heras Alberto Muñoz , Porras Diego , González-Tudela Alejandro 
Published: February 2025

Abstract
Photonic quantum metrology enables the measurement of physical parameters with precision surpassing classical limits by using quantum states of light. However, generating states providing a large metrological advantage is hard because standard probabilistic methods suffer from low generation rates. Deterministic protocols using non-linear interactions offer a path to overcome this problem, but they are currently limited by the errors introduced during the interaction time. Thus, finding strategies to minimize the interaction time of these non-linearities is still a relevant question. In this work, we introduce and compare different deterministic strategies based on continuous and programmable Jaynes–Cummings and Kerr-type interactions, aiming to maximize the metrological advantage while minimizing the interaction time. We find that programmable interactions provide a larger metrological advantage than continuous operations at the expense of slightly larger interaction times. We show that while for Jaynes–Cummings non-linearities the interaction time grows with the photon number, for Kerr-type ones it decreases, favoring the scalability to big photon numbers. Finally, we also optimize different measurement strategies for the deterministically generated states based on photon-counting and homodyne detection.
Establishing continuous reference intervals for liver function analytes using fractional polynomial regression
Authors: Derici Yıldırım Didem , Balcı Fidancı Şenay , Türkegün Şengül Merve , Çimen M. Burak Y. , Tamer Lülüfer 
Published: February 2025

Abstract

Objectives
Reference intervals (RIs) play a crucial role in contemporary healthcare by providing critical support for clinical decision-making. RI calculation methods have certain limitations. They cannot capture age-related variations in laboratory values and non-linear relations between variables. Therefore, alternative methods that preserve the continuous type of age and consider non-linear relations must be explored. This study aimed to suggest an alternative method, namely, fractional polynomial (FP) regression models, to overcome these limitations and estimate the reference limits based on this method for ALT and AST markers.

Methods
This retrospective study is conducted on a large hospital database to establish continuous age and sex-specific RIs for ALT and AST in a Turkish population. The study included 4,386 and 2,834 individuals for ALT and AST, respectively, aged 18–92 years. FP models and a non-parametric approach are used to calculate RIs.

Results
For AST in females, a linear model indicated the relationship between age and AST in females (p=0.673). However, more complex models (m0=4) were explored for female ALT values. After several comparisons, the FP3 model was chosen as the best fit (p=0.098). For male ALT and AST, FP analysis showed no significant age-related effects (p=0.679 and p=0.507, respectively). Therefore, traditional non-parametric methods were used to calculate RIs.

Conclusions
Compared with discrete RIs, continuous RIs are more accurate. Laboratories should determine RIs that reflect their population. Future research could explore the application of FP models in the pediatric population.
The Organization and Development of Shevchenko Studies in the All-Ukrainian Academy of Sciences (1921–1934)
Authors: Karpinchuk Halyna 
Published: February 2025

The becoming of academic Shevchenko studies began in the 1920s, after the formation of the All-Ukrainian Academy of Sciences of the Ukrainian SSR (hereinafter – VUAN) – the centre that united the scientific forces of Ukrainians.This paper covers the organization of research work of Shevchenko scholars in various societies and committees of the Academy. First of all, Shevchenko’s works were the subject of research by the Historical and Literary Society [Історично-літературне товариство; 1922–1928] in Kyiv as well as scientific societies of Odesa, Poltava, and St. Petersburg, which cooperated with the Ukrainian Academy. The achievement of the Historical and Literary Society was the publication of the two-volume Poetry [Поезія] book by Shevchenko in 1927. In total, the two volumes contain 246 poems.Shevchenko’s work was investigated most intensively by the Committee for Publishing the Works of Modern Ukrainian Literature [Комісія для видавання творів новітнього українського письменства], which was headed by the academic and the vice-president of the VUAN, S. Yefremov. Its greatest achievement was the publication of two out of the planned 10 volumes of Shevchenko’s Complete Works Correspondence [Листування] and Diary [Щоденник] that was supported by 1,100 pages of comments. Separate studies about the poet appeared in the Committee for Compiling a Dictionary of the Living Ukrainian Language [Комісії для складання словника живої української мови] and the Committee for Studies of Public Currents in Ukraine [Комісія для дослідів громадських течій на Україні], etc.We should note the general problem in philology at that time – the lack of a coherent presentation of Shevchenko’s literary and artistic heritage as well as his scientific biography. The paper outlines the contribution to the development of Shevchenko studies made by the Academy employees: S. Yefremov, V. Miyakovsky, M. Novytsky, O. Novytsky, P. Fylypovych, and others.From the second half of the 1920s, Shevchenko studies advanced actively at the Taras Shevchenko Institute, which was opened in 1926 as an independent institution.Shevchenko studies reached a turning point in the 1930s: academic Shevchenko studies were replaced by Soviet Shevchenko studies, subordinated to the party’s marxist-leninist ideology. Arrests and murders of patriotic-leaning Ukrainians intensified, including the Academy’s employees. Their works were removed from libraries and severely criticized. There was no way that all of this would not affect the development of Shevchenko studies.