bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALISIS KUALITAS AIR SUNGAI CISANGKAN KOTA CIMAHI PROVINSI JAWA BARAT
Authors: Rosmeiliyana Rosmeiliyana , Wardhani Eka 
Published: August 2021

Sungai Cisangkan merupakan sungai yang mengalir di Kota Cimahi yang menerima limbah domestik, industri, dan pertanian yang berasal dari daerah aliran sungai. Perkembangan industri dan pemukiman di sepanjang aliran sungai menyebabkan kualitas air sungai menurun. Penelitian ini bertujuan untuk menganalisis kualitas air Sungai Cisangkan berdasarkan baku mutu menurut PP Nomor 82/2001 kelas 2. Analisis kualitas air dilakukan di 3 titik mewakili bagian hulu, tengah dan hilir sungai. Data dikumpulkan pada 3 periode pengambilan yaitu Bulan April, September, dan Desember 2019. Parameter yang diukur dan diamati sebanyak 32 parameter yang terdiri dari parameter fisika, kimia, dan mikrobiologi. Berdasarkan hasil penelitian terdapat 16 parameter yang tidak memenuhi baku mutu terdiri dari 2 parameter fisika, 14 kimia, dan 2 mikrobiologi. Berdasarkan parameter yang tidak memenuhi bakumutu sumber pencemar dominan diprediksi berasal dari aktivitas pemukiman karena nilai BOD5, COD, TSS, minyak dan lemak, detergen MBAS, Total Coliform serta fecal Coliform tidak memenuhi baku mutu di seluruh titik sampling pada 3 kali pengukuran. Hasil penelitian dapat dijadikan sebagai data dasar pengelolaan limbah cair domestik di DAS Cisangkan Kota Cimahi. Kata kunci: Cimahi, Cisangkan, domestik, kualitas air. The Cisangkan River is a river that flows in Cimahi City which receives domestic, industrial and agricultural waste originating from the watershed. Industrial and residential developments along the river have caused the quality of river water to decline. This study aims to analyze the quality of Cisangkan River water based on quality standards according to PP No. 82/2001 class 2. Water quality analysis was carried out at 3 points representing the upstream, middle and downstream parts of the river. Data were collected in 3 periods of collection, namely April, September, and December 2019. The parameters measured and observed were 32 parameters consisting of physical, chemical, and microbiological parameters. Based on the research results, there are 16 parameters that do not meet the quality standards consisting of 2 physical parameters, 14 chemistry, and 2 microbiology. Based on the parameters that do not meet the quality standards, the dominant pollutant sources are predicted to come from residential activities because the values of BOD5, COD, TSS, oil and fat, detergent MBAS, Total Coliform and fecal Coliform do not meet the quality standards at all sampling points at 3 measurements. The results of the research can be used as basic data for domestic liquid waste management in the Cisangkan River Basin, Cimahi City. Keywords: Cimahi, Cisangkan, domestic, water quality.
PENGAMALAN NILAI-NILAI PANCASILA DALAM MENINGKATKAN LITERASI BUDAYA MENYONGSONG ERA REVOLUSI 4.0 di SMKN 3 BANJARBARU
Authors: Aisyah Siti 
Published: August 2021

Tujuan penelitian ini ialah untuk melihat implementasi pengamalan nilai-nlai Pancasila dalam meningkatkan literasi budaya dan kewargaan untuk menyongsong era revolusi 4.0 dengan media mata pelajaran PPKn. Penelitian ini menggunakan pendekatan kualitatif, dan data dikumpulkan melalui observasi dan wawancara. Hasil penelitian ini menyimpulkan bahwa menumbuhkan kesadaran berkonstitusi di sekolah akan lebih efektif dilaksanakan pada saat proses pelaksanaan belajar mengajar. Di samping itu peserta didik diharapkan dapat memberikan ungkapan atau dalam bentuk tulisan yang berkaitan dengan kesadaran berkonstitusi melalui kegiatan praktik kewarganegaraan sehingga proses pembelajaran menjadi aktif dan kreatif. Pendidikan Kewarganegaraan mempunyai peranan yang strategis dalam mengimplementasikan pendidikan kesadaran berkonstitusi. Selain itu, materi muatan konstitusi amat relevan untuk memperkaya materi Pendidikan Pancasila dan Kewarganegaraan. Oleh karena itu, untuk mengoptimalkan peran mata pelajaran PPKn tersebut, diperlukan upaya untuk memperkuat konsep PPKn sebagai media pendidikan kesadaran dalam mengalamalkan nilai-nilai Pancasila dalam upaya meningkatkan literasi budaya dan kewargaan. Kata Kunci : Implementasi, Literasi Budaya, Pancasila, Revolusi Industri 4.0.
KONSEP PERTANGGUNGJAWABAN BERDASARKAN ASAS VICARIOUS LIABILITY DALAM TINDAK PIDANA KEBAKARAN HUTAN DAN LAHAN
Authors: Abby Fathul Achmadi , Arif Junaidi 
Published: August 2021

Pemakaian asas Vicarious Liability terhadap korporasi akan membuat celah dan kesempatan agar korporasi tersebut tetap berjalan jikalau hanyalah pemimpin ataupun direktur yang dikenakan pertanggungjawaban pidana nya tersebut. Dalam penerapannya pemimpin dan direktur dari suatu perusahaan saja yang dapat dijadikan tersangka dari sebuah korporasi yang melakukan suatu peristiwa tindak pidana, korporasi yang lepas tanggungjawab maka tidak ada pencabutan izin, denda, ataupun hal yang merugikan untu korporasi itu sendiri hanyalah kerugian untuk individu yaitu pemimpin atau direktur dari perusahaan tersebut. Penelitian ini dilakukan dengan jenis penelitian yuridis analisis. Penelitian yuridis analisis mempunyai sifat penelitian deskriptif analisis, yang mana, penelitian deskriptif analisis adalah suatu penelitian yang menggambarkan, menelaah, menjelaskan, dan menganalisis suatu peraturan hukum. Penelitian ini mempergunakan metode yuridis normatif, dengan pendekatan yang bersifat kualitatif. Metode penelitian yuridis normatif adalah metode penelitian yang mengacu pada norma-norma hukum yang terdapat dalam peraturan perundang-undangan dalam Perspektif Peradilan Pidana.kerusakan lingkungan hidup yang terjadi dilahan perkebunan kelapa sawit PT. PALMINA UTAMA. Kebakaran di HGU PT. Palmina Utama tejadi dikarenakan PT. Palmina Utama tidak melengkapi sarana prasarana tanggap darurat yang memadai sehingga pada saat terjadinya kebakaran perusahaan tidak dapat secara maksimal menanggulanginya, Korporasi secara melawan hukum dengan sengaja melakukan perbuatan yang mengakibatkan kebakaran hutan dapat dimintai pertanggung jawaban pidananya berdasarkan Pasal 49 Undang-Undang No. 41 Tahun 1999 tentang Kehutanan serta mewajibkan pemegang izin sebagaimana diatur dalam Pasal 27 dan Pasal 29 untuk menjaga, memelihara, dan melestarikan hutan tempat usahanya. Pasal 49 UU No 41 Tahun 1999 menyebutkan pemegang hak atau izin bertanggung jawab atas terjadinya kebakaran hutan di areal kerjanya Kata Kunci : pertanggungjawaban; korporasi; vicarious Liability
Is Gastrocnemius Tightness a Normal Finding in Children?
Authors: Liyanarachi Suki , Hulleberg Gunn , Foss Olav A. 
Published: August 2021

Background:
Isolated gastrocnemius tightness has been associated with several foot conditions. We do not know whether gastrocnemius tightness is a normal finding in the developing child or whether tightness is associated with foot symptoms. Recurrent foot and leg pain is common in children, and more knowledge of gastrocnemius tightness is of interest.

Methods:
Passive ankle dorsiflexion was measured with the knee flexed and extended (Silfverskiöld test) in 204 Norwegian schoolchildren (408 feet). School classes from 4 different age groups were recruited (5 to 6 years, 8 to 9 years, 11 to 12 years, and 14 to 15 years). Footprints were also recorded in order to assess for any association between foot morphology and dorsiflexion results, specifically, gastrocnemius tightness.

Results:
Ankle dorsiflexion decreased with increasing age. The thresholds for equinus contracture were set at either ≤5° or ≤0° of ankle dorsiflexion when measured with the knee extended, and the Silfverskiöld test was considered to be positive when ankle dorsiflexion was reduced by ≥10° from the flexed knee position to the extended knee position. The rate of gastrocnemius tightness was 54.9% if the threshold was set at ≤5° and only 3.7% if the threshold was set at ≤0°. The data did not provide evidence of an association between dorsiflexion and footprints.

Conclusions:
Ankle dorsiflexion decreased with increasing age in this population of schoolchildren, highlighting the importance of age-matched norms. A majority had a tight gastrocnemius when the ankle dorsiflexion threshold was set at ≤5°, indicating that isolated gastrocnemius tightness should not be interpreted as a pathological finding.

Level of Evidence:
Diagnostic Level II. See Instructions for Authors for a complete description of levels of evidence.
Awareness and Acceptance Of Genetic Modified Food (GMF) Among The Malaysian Consumers
Authors: A.M.Z Azlin , R Baki , M.S.K Enio , Abdullah, S. J. Ho 
Published: August 2021

The halal industry is growing vigorously to cater the Muslim consumers in Malaysia. The acceptance, awareness and perception towards the genetic modified food (GMF) is still insufficient to fulfil the Malaysian market and expectantly plays a major role in a long period. The purpose of this paper is to fill the knowledge gap to the study of GMF conducted in Malaysia. Qualitative data were collected via open-ended interview with four participants from various background namely Malaysian Agricultural Research and Development Institute (MARDI) researcher, P3, P4 and P1 by using single case and different site. All interviews were audio recorded, transcribed and analysed. Almost all participants familiar with the term genetic modified organism (GMO) or genetic modified food (GMF) which are two different entities but similar in biotechnology scope. Almost all participants were familiar with the term of genetic modified food. Since most of the participants came out with the science and biotechnology background, they perceived the GMF product but some of them did not trust of these products for various reasons. The participants agreed on the need for more information from a trusted and credible source that can easily access by the consumers. This study provides an in-depth insight into consumer’ awareness, perception and evaluation concerning the halalan toyyiban status of genetic modified food in Malaysia. The novelty of these finding could provide information for the biotechnology food industry to expand its market and develop its profitability and reliability to promo sustainable food production and consumption in the population.
Pengaruh Job Insecurity, Kepuasan Kerja dan Stres Kerja Terhadap Turnover Intention dengan Komitmen Organisasi Sebagai Variabel Intervening pada PT Lumina Packaging
Authors: Wulanfitri Eki , Sumartik Sumartik , Indayani Lilik 
Published: August 2021

This study aims to examine the Influence of Job Insecurity, Job Satisfaction and Job Stress on Turnover Intention with Organitational Commitment as Intervening Variable.This research uses a quantitive approach with a survey method. The sampling technique uses simple random sampling. The population in this study amounted 291 employees and the sample used amounted 75 employees of PT Lumina Packaging. Technical data analysis using Partial Least Squares (PLS) with Warppls 5.0 software. The result of this research found that Job Insecurity have a direct and significant effect on Turnover Intention by 28%, Job Satisfaction have a direct and significant effect on Turnover Intention by 41%, Job Stress have a direct and significant effect on Turnover Intention by 19%, Job Insecurity have a direct and significant effect on Organitational Commitment by 24%, Job Satisfaction have a direct and significant effect on Organitational Commitment by 19%, Job Stress have a direct and significant effect on Organitational Commitment by 20%, and Organitational Commitment have a direct and significant effect on Turnover Intention by 23%. Job Insecurity have an indirect effect on Turnover Intention through Organitational Commitment as an intervening variable by 47%, Job Satisfaction have an indirect effect on Turnover Intention through Organitational Commitment as an intervening variable 42%, Job Stress have an indirect effect on Turnover Intention through Organitational Commitment as an intervening variable by 43%.
Service Quality Management Dimensions and Its Effect on The Students’ Satisfaction: An Empirical study Amongst Secondary Schools in Pakistan
Authors: Naveed Jabbar Muhammad , Hussin Fauzi , Javeed Assi Khalid 
Published: August 2021

Because the cost of attracting the fresh customers is much advanced than cost of retaining current and old customers, possession on students’ satisfaction has become scorching debate in modern era. Service quality management plays its vital role for this concern. This current research paper aims to highlight the concepts of service quality management dimensions and its effect on students’ satisfaction. In this study, the dependent variable was students’ satisfaction that measured by the independent variable service quality. The secondary school students of public and private education institutions were the population of this study in Punjab Pakistan. Random sampling approach applied for the delimitation of the population. Sample was 727 students (public 345, private 382). Five point Likert scale used in questionnaire for the collection of data. This study adopted from Parasuraman’S SERVEQUAL dimensions model (1991). The test applied for analysis: Descriptive analysis, Factor analysis, independent sample t-test and Pearson Correlation. The findings of the study show that the quality of the public secondary schools was better as compare to private school. The correlation was resulted between .7 to .8, It shows that there was a significance effect of service quality management on students’ satisfaction. The paper provides the guidance for sort out the most effective factors about the customers’ satisfaction regarding service quality. This research study will prove as a stepping-stone for the development of the managerial strategies. It will also helpful for educational leaders, policy makers and head of the department for the development of quality education.
Liver injury changed the biological characters of serum small extracellular vesicles and reprogramed hepatic macrophages in mice
Authors: Lv Xiufang , Zhang Anqi , Liu Weiqi , Zhao Min , Li Jing , He Li , Cheng Li , Sun Yufeng , Qin Gang , Lu Peng , Ji Yuhua , Ji Juling 
Published: August 2021

Abstract
BACKGROUNDSerum small extracellular vesicles (sEVs) and their small RNA (sRNA) cargoes could be promising biomarkers for the diagnosis of liver injury. However, the dynamic changes in serum sEVs and their sRNA components during liver injury have not been well characterized. Given that hepatic macrophages can quickly clear intravenously injected sEVs, the effect of liver injury-related serum sEVs on hepatic macrophages deserves to be explored.AIMTo identify the characteristics of serum sEVs and the sRNAs they contain during liver injury and explore their effects on hepatic macrophages.METHODSTo identify serum sEV biomarkers for liver injury, we established a carbon tetrachloride-induced mouse liver injury model in C57BL/6 mice to simulate acute liver injury (ALI), chronic liver injury (CLI) and recovery. Serum sEVs were obtained and characterized by transmission electron microscopy and nanoparticle tracking analysis. Serum sEV sRNAs were profiled by sRNA sequencing. Differentially expressed microRNAs (miRNAs) were compared to mouse liver-enriched miRNAs and previously reported circulating miRNAs related to human liver diseases. The biological significance was evaluated by Ingenuity Pathway Analysis of altered sEV miRNAs and conditioned cultures of ALI serum sEVs with primary hepatic macrophages.RESULTSWe found that both ALI and CLI changed the concentration and morphology of serum sEVs. The proportion of serum sEV miRNAs increased upon liver injury, with the liver as the primary contributor. The altered serum sEV miRNAs based on mouse studies were consistent with human liver disease-related circulating miRNAs. We established serum sEV miRNA signatures for ALI and CLI and a panel of miRNAs (miR-122-5p, miR-192-5p, and miR-22-3p) as a common marker for liver injury. The differential serum sEV miRNAs in ALI contributed mainly to liver steatosis and inflammation, while those in CLI contributed primarily to hepatocellular carcinoma and hyperplasia. ALI serum sEVs decreased both CD86 and CD206 expression in monocyte-derived macrophages but increased CD206 expression in resident macrophages in vitro.CONCLUSIONSerum sEVs acquired different concentrations, sizes, morphologies and sRNA contents upon liver injury and could change the phenotype of liver macrophages. Serum sEVs therefore have good diagnostic and therapeutic potential for liver injury.
Milonine Protects Against Acute Lung Injury By Modulating The Akt And NF-κB Signaling Pathway
Authors: Bernardo Larissa Rodrigues , Ferreira Laércia Karla Diega Paiva , Ferreira Larissa Adilis Maria Paiva , Vieira Cosmo Isaías Duvirgens , de Oliveira João Batista , de Lima Louise Mangueira , Alves Adriano Francisco , Araújo Rubens da Silva , Maia Mayara dos Santos , Scotti Marcus Tullius , Filho José Maria Barbosa , Piuvezam Marcia Regina 
Published: August 2021

Abstract
Acute lung injury (ALI) is an inflammation that triggers acute respiratory distress syndrome (ARDS) with perialveolar neutrophil infiltration, alveolar-capillary barrier damage, and lung edema. Activation of the toll-like receptor 4 complex and its downstream signaling pathways are responsible for the cytokine storm and cause alveolar damage on ARDS. Due to the complexity of inflammatory events on ALI, a defined pharmacotherapy has not been established. Thus, this study aimed to evaluate the anti-inflammatory potential of milonine, an alkaloid of Cissampelos sympodialis Eichl, in an ALI experimental model. BALB/c mice were lipopolysaccharide (LPS)-challenged and treated with milonine at 2.0 mg/kg. Twenty-four hours later, the bronchoalveolar lavage fluid (BALF), peripheral blood, and lungs were collected for cellular and molecular analysis. The milonine treatment decreased the inflammatory cell migration (principally neutrophils) to the alveolar cavity, the protein exudate, the pulmonary edema, and the level of pro-inflammatory cytokines (IL-1β, IL-6, TNF-α) into the BALF. The systemic level of IL-6 level was also reduced. In the lung tissue, milonine reduced the bronchoalveolar damage. The milonine docking analyzes demonstrated that the molecule formed hydrophobic interactions with the amino-acids Ile124 and Phe126 of the TLR4/MD2 groove. Indeed, the anti-inflammatory effect of milonine was due to the negative regulation of cytoplasmic kinase-Akt and NF-κB by interacting with the TLR4/MD2 complex. Therefore, milonine is an effective inflammatory modulator by blocking the interaction of the LPS-TLR4/MD2 complex and downregulating the intracellular inflammatory pathway axis being a potential molecule for the treatment of ALI.
Researching the Researchers: Psychological Distress and Psychosocial Stressors According to Career Stage in Mental Health Researchers
Authors: Hill Nicole TM , Bailey Eleanor , Benson Ruth , Cully Grace , Kirtley Olivia , Purcell Rosemary , Rice Simon , Robinson Jo , Walton Courtney 
Published: August 2021

Abstract
Background Although there are many benefits and privileges associated with working in academia, this career path often involves a range of structural and organisational stressors that can be detrimental to wellbeing and increase susceptibility to mental ill health among academic staff and students. This exploratory study examines experiences of work-related stressors, psychological distress, and mental health diagnoses among mental health researchers. Differences in outcomes were compared across career stages including postgraduate students, research support staff, early-middle career researchers, and senior researchers. MethodsThis international cross-sectional study involved 207 mental health researchers who were post-graduate students or employed in research institutes or university settings. Work-related psychosocial stressors were measured by the Copenhagen Psychosocial Questionnaire III (COPSOQ-III). Psychological distress was assessed using Depression-Anxiety-Stress Scale-21 (DASS-21). Thoughts of suicide was assessed using three questions adapted from the Patient Health Questionnaire-9 (PHQ-9). History of mental-health diagnoses was assessed through a custom questionnaire. Pearson’s chi-square test of independence was used to compare mental health diagnoses and suicidal ideation across career stages (research support staff, students, early-middle career researchers, and senior researchers). Group comparisons of work-related psychosocial exposures and DASS-21 general distress and related sub-scores were conducted across career stages. Results Differences in ‘demands at work’ and the ‘work-life balance’ domain were observed across career stages, with scores lowest among support staff (p=0.01). In contrast, scores in ‘social capital’ and ‘health and wellbeing domains’ were highest among research support staff (P= 0.01). Overall, 13.4% of respondents met the threshold for severe psychological distress, which was significantly higher in students compared to participants from other career stages (p=0.01). Among the subgroup of participants who responded to the question on mental health diagnoses and suicidal ideation (n=152), 54% reported a life-time mental health diagnosis and 23.7% reported suicidal ideation since academic career commencement. ConclusionsDespite working in the same environment, research support staff report experiencing significantly less psychosocial stressors compared to postgraduate students, early-middle career researchers and senior researchers. Future research that targets the modifiable stressors at each career stage could improve the overall mental health and wellbeing of mental health researchers.