bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rotavirus Vaccine Safety and Effectiveness in Infants With High-Risk Medical Conditions
Authors: van Dongen Josephine A.P. , Rouers Elsbeth D.M. , Schuurman Rob , Band Caterina , Watkins Shannon M. , van Houten Marlies A. , Bont Louis J. , Norbruis Obbe F. , Hemels Marieke A.C. , van Well Gijs T.J. , Vlieger Arine M. , van der Sluijs Jacqueline , Stas Helene G. , Tramper-Stranders Gerdien , Kleinlugtenbeld Elly A. , van Kempen Anne A.M.W. , Wessels Margreet , van Rossem Maaike C. , Dassel Carin A.C.M. , Pajkrt Dasja , Bonten Marc J.M. , Bruijning-Verhagen Patricia C.J. 
Published: November 2021

OBJECTIVES
Rotavirus vaccination has 87% to 100% effectiveness against severe rotavirus acute gastroenteritis (AGE) in healthy infants in high-income countries. Little is known whether infants with medical risk conditions (MRCs) are equally protected and if the vaccine is equally well tolerated. We conducted a quasi-experimental prospective multicenter before-after cohort study to assess the vaccine effectiveness (VE) and safety profile of the human rotavirus vaccine (HRV) among MRC infants that required prolonged or frequent postnatal care.

METHODS
The Netherlands has no national rotavirus immunization program, but HRV was implemented in routine care for MRC infants in 13 Dutch hospitals. Participants in the before and after cohort, HRV unvaccinated and vaccinated, respectively, were followed for occurrence of (rotavirus) AGE. VE of at least 1 dose was estimated by using time-to-event analysis for severe rotavirus AGE. Vaccine-related serious adverse event (AEs) after HRV were retrieved systematically from medical charts. Solicited AEs after vaccinations were prospectively collected and compared between vaccination time points with or without HRV.

RESULTS
In total, 1482 high-risk infants with MRC were enrolled, including 631 in the before and 851 in the after cohorts; 1302 infants were premature (88.3%), 447 were small for gestational age (30.2%), and 251 had at least 1 congenital disorder (17.0%). VE against severe rotavirus AGE was 30% (95% confidence interval [CI]: −36% to 65%). Overall, the observed number of rotavirus hospitalizations was low and not significantly different between the cohorts (2 and 2, respectively). The rate of vaccine-related serious AE was 0.24 per 100 vaccine doses. The adjusted risk ratio for any AE after HRV vaccination compared with other routine vaccinations was 1.09 (95% CI: 1.05 to 1.12) for concomitant administration and 0.91 (95% CI: 0.81 to 0.99) for single HRV administration. Gastrointestinal AEs were 10% more frequent after HRV.

CONCLUSIONS
In contrast to previous findings among healthy term infants, in routine use, HRV offered limited protection to vulnerable medical risk infants. HRV is generally well tolerated in this group in single administration, but when coadministered with routine vaccines, it is associated with higher risk of (mostly gastrointestinal) AE. Our study highlights the importance of studying vaccine performance in subgroups of medically vulnerable infants.
Child Care Center Hand Hygiene Programs’ Cost-Effectiveness in Preventing Respiratory Infections
Authors: Azor-Martinez Ernestina , Garcia-Mochon Leticia , Lopez-Lacort Monica , Strizzi Jenna Marie , Muñoz-Vico Francisco Javier , Jimenez-Lorente Carmen Pilar , Fernandez-Campos Maria Amparo , Bueno-Rebollo Cristina , del Castillo-Aguas Guadalupe , Balaguer-Martinez Josep Vicent , Gimenez-Sanchez Francisco 
Published: November 2021

BACKGROUNDWe previously demonstrated that a hand hygiene program, including hand sanitizer and educational measures, for day care center (DCC) staff, children, and parents was more effective than a soap-and-water program, with initial observation, in preventing respiratory infections (RIs) in children attending DCCs. We analyzed the cost-effectiveness of these programs in preventing RIs.METHODSA cluster, randomized, controlled and open study of 911 children aged 0 to 3 years, attending 24 DCCs in Almeria. Two intervention groups of DCC-families performed educational measures and hand hygiene, one with soap-and-water (SWG) and another with hand sanitizer (HSG). The control group (CG) followed usual hand-washing procedures. RI episodes, including symptoms, treatments, medical contacts, complementary analyses, and DCC absenteeism days, were reported by parents. A Bayesian cost-effectiveness model was developed.RESULTSThere were 5201 RI episodes registered. The adjusted mean societal costs of RIs per child per study period were CG: €522.25 (95% confidence interval [CI]: 437.10 to 622.46); HSG: €374.53 (95% CI: 314.90 to 443.07); SWG: €494.51 (95% CI: 419.21 to 585.27). The indirect costs constituted between 35.7% to 43.6% of the total costs. Children belonging to the HSG had an average of 1.39 fewer RI episodes than the CG and 0.93 less than the SWG. It represents a saving of societal cost mean per child per study period of €147.72 and €119.15, respectively. The HSG intervention was dominant versus SWG and CG.CONCLUSIONSHand hygiene programs that include hand sanitizer and educational measures for DCC staff, children, and parents are more effective and cost less than a program with soap and water and initial observation in children attending DCCs.
Dante Alighieri, Komédia I. Pokol. Kommentár, szerk. Kelemen János, közrem. Berényi Márk, Draskóczy Eszter, Hoffmann Béla, Mátyus Norbert, Nagy József, Tóth Tihamér, Budapest, ELTE Eötvös Kiadó, ELTE BTK, 2019
Authors: Szovák Márton 
Published: November 2021

Recenzió a Magyar Dantisztikai Társaság Pokol-kommentárjáról.
Több mint 550 oldalon, keménykötésben foghatja végre kezébe az olvasó Dante Alighieri Isteni színjátékának az első részét kísérő tudományos kommentárt. Bár a szerző idestova hétszáz éve meghalt, élete főművét az azóta eltelt időben folyamatosan értelmezték és újraértelmezték, nemcsak a Commedia poétikai kiválósága, hanem talán az abban rögzített világkép és -rend nyújtotta stabilitás és biztonságérzet vonzósága miatt is. Akár a középkor gondolkodását akarja belőle jobban megérteni az ember, akár a saját világnézetét tenné próbára a dantei tükörben, a Commedia olyan fogódzó, amely még sokáig segítségére lesz az ilyen kérdésekkel küzdő olvasónak. A mű aktualitását jelzi, hogy nemrég Ferenc pápa is újraolvasásra ajánlotta a művet, hogy „tudatosuljon bennünk száműzöttségünk, és hagyjuk, hogy elindítsa bennünk a megtérés folyamatát a rendezetlenségből a bölcsesség, a bűnből az életszentség, a nyomorból a boldogság, a pokol szörnyűségének szemléléséből a paradicsom boldogító megtapasztalása felé.” Persze a második „nagy lemondás” (Pokol, III, 60.) haszonélvezője helyében én sem mondanék rosszat Dantéról és művéről, de ezt majd a kellő időben megbeszélik ők ketten az égi rózsa valamelyik szirmán üldögélve. Ugyancsak a Commedia iránti érdeklődés jele, hogy 2016-ban jelent meg Nádasdy Ádám új magyar fordítása részletes jegyzetapparátussal, magyarázó ábrákkal és táblázatokkal. De akkor mivégre az újabb kiadvány?
A kalendárium és használója
Authors: Bódai Dalma 
Published: November 2021

Thurzó György naplói a kora újkori napló kialakulásának kezdeti jegyeit viselik magukon. Az 1596-os, 1697-es, 1604-es, 1607-es és 1612-es évekből fennmaradt naplók alapvetően udvari naplóként értelmezhetők, de az utazási naplók és nyomokban a személyes naplók szabályszerűségei is felfedezhetők a szövegeken. A főúr környezetében már a 16. század közepétől meghonosodott naplóvezetési hagyományok, illetve a feleségének írt levelek alapján feltételezhető, hogy a 16. század végétől haláláig, 1616-ig folyamatosan vezetett, illetve írnokai vezettek kalendáriumba írt naplókat. Ezt erősíti meg Thurzó Imre 1617-es évben írt naplója, amely egyértelműen Thurzó György naplóvezetési szokásait viszi tovább, azonban némiképp kiforrottabb módon.
Thurzó György nádor a kalendáriumok nyomtatott naptári részét az idő múlásának számontartására, a bele írt feljegyzéseket pedig a mindennapjai történéseseinek megörökítésére, ily módon mintegy az idővel való elszámolásra használta. Arra vonatkozóan viszont nem maradt fenn utalás, hogy a prognosztikonok szövegeinek és előrejelzéseinek hasznát vette-e, és ha igen milyen módon.
Thurzó György naptárbejegyzéseiben mindennapi életének szubjektív élményei jelennek meg. Az eseményeket az adott pillanatban szemléli, nem reflektált a kor eseményeire, nem következtetett és retrospektív megjegyzéseket sem tett a szövegekbe. A naplók praktikus és nem esztétikai célokat szolgált, elsősorban ez emlékezet segítését, illetve tehermentesítését. Azonban láthatóan ezt sem hosszú távra vonatkoztatva, hiszen a kalendáriumok és bennük a naplók megőrzése láthatóan Thurzó György és fia, Imre számára sem volt fontos. Sokkal inkább rövid távon, pár hónap, esetleg néhány év távlatában őriztek meg általuk visszakereshető módon az udvar mindennapi működésére vonatkozó adatokat.
Агломерации Азербайджана: тенденции демографического и социально-экономического развития
Authors: Этибар Санан оглы Бадалов 
Published: November 2021

В статье анализируется историческое развитие и формирование процесса субурбанизации и его влияние на городское расселение Азербайджана. Анализируется динамика роста населения и особенности демографических процессов, а также проблемы социально-экономического развития в городских агломерациях. Так, в постсоветский период произошло увеличение территорий агломераций за счет сельских поселений, получивших статус городского поселка. Происходят функциональные изменения периферии Бакинской и Гянджинской агломераций, где формируются новые промышленные парки, зоны размещения научно-исследовательских организаций и предприятий высоких технологий, а также агропарки и сосредоточения объектов сферы услуг. Автор выявляет трансформации территориальной организации больших и крупных городских агломераций.
Проведен анализ воздействия урбанизации на демографические процессы, в том числе на изменение естественного и миграционного движения населения, половозрастной структуры и брачно-семейного состава населения.
В агломерациях сосредоточено 72,5% всего городского населения республики, и его численность быстро растет. Основным компонентом такого роста является естественный прирост (более 70%), тогда как миграция обеспечивает чуть более 10% прироста. За последние годы произошло неуклонное снижение показателей коэффициентов рождаемости и естественного прироста, снижаются показатели заключения браков и увеличивается количество разводов.
Пространственные структуры постсоциалистических пригородов: функциональные и социальные центры субурбии Махачкалы
Authors: Дохов Руслан Ахмедович , Алов Иван Николаевич , Шубина Дарья Олеговна , Волков Максим Сергеевич , Мацур Владимир Александрович , Умнова Татьяна Николаевна , Анна Романовна Шерстнева 
Published: November 2021

В постсоциалистический период большая часть нестоличных городов бывших социалистических стран испытала стагнацию или сжатие. Однако некоторые из них, напротив, перешли к бурному росту как численности населения, так и застроенной территории. В результате за 30 лет развития в рыночных условиях сформировались протяженные пригородные ареалы. На примере Махачкалы мы рассмотрели внутреннюю структуру этих новых постсоциалистических пригородов. На основе полевых материалов были выделены, типологизированы и сопоставлены между собой функциональные и социальные центры махачкалинской субурбии. Их пространственные структуры частично обусловливают друг друга. Производство социальности в пригородах, в условиях сниженной плотности населения и ослабленности советского городского ядра масштабной эмиграцией, затруднено. Функциональные центры пригородов Махачкалы крайне разнообразны. От осевых центров-линий, продолжающих собственно старый центр города и ориентированных на транзитный поток потребителей, отходят внутрь жилых районов более мелкие центры-линии, функциональное разнообразие которых удовлетворяет локальный спрос. Первичный пионерный тип центра — ядра, состоящие из одиночных магазинов, — доминирует в наименее функционально плотных районах недавней застройки.
В удаленных районах ядро может немного усложняться, тогда возникают комбинации мечетей, магазинов и школ, выступающие местами концентрации социальных практик. Мечети чаще входят в состав ядер в старых районах-селах.
В удаленных районах формируются центры-облака, сосредотачивающие много разнообразных объектов и становящиеся аналогами центральных площадей. Сложных пространственных форм концентрации социальных практик почти не формируется. В основном это одиночные ядра. Распространены как косвенные проявления социального контроля через граффити и плакаты, так и прямые — силами местных неформальных «дружин», в особенности в изолированных этнических пригородах.
Randomized Controlled Trial Study of the Impact of a Spiritual Intervention on Hope and Spiritual Well-Being of Persons with Cancer
Authors: Afrasiabifar Ardashir , Mosavi Asadollah , Jahromi Abolfazl Taghipour , Hosseini Nazafarin 
Published: November 2021

Objective. To determine the impact of spiritual intervention on hope and spiritual well-being of persons with cancer
Methods. Randomized controlled trial in which 74 patients with cancer referring to a chemotherapy ward of Shahid Rajaie Hospital in Yasuj city, Iran, were participated. The eligible patients were randomly assigned to either intervention or control group. Spiritual-based intervention was performed based on the protocol in four main fields namely; religious, existence, emotional and social over 5 sessions before chemotherapy.The participants in the control group had received usual cares .Data were collected using Snyder's Hope Scale and Ellison's Scale Spiritual Well-Being Scale on a week before and after intervention.
Results. The total mean scores of the scales of hope and spiritual well-being in both groups did not present statistical differences in the pre-intervention assessment. In contrast, at the post assessment, significant differences (p<0.001) were found in the mean scores between the intervention and control groups on the hope scale (60.9 versus 39.8) and on the spiritual well-being scale (94.3 versus 71.6).
Conclusion. Spiritual intervention could promote hope and spiritual well-being of persons with cancer.
Poor glycemic control and associated factors in diabetic people attending a reference outpatient clinic in Mato Grosso, Brazil
Authors: Espinosa Mariano Martínez , Almeida Vitesinha Rosa dos Santos , Do Nascimento Vagner Ferreira 
Published: November 2021

Objective. To identify the proportion of poor of glycemic control and associated factors among people with type 2 diabetes attending a regional reference outpatient clinic in Mato Grosso (Brazil).
Methods. This is a cross-sectional quantitative study based on data from medical records of 338 people with type 2 diabetes who attend a state reference outpatient clinic in Mato Grosso (Brazil). Information on glycemic control, sociodemographic factors, lifestyle and clinical conditions was collected.
Results. The prevalence of elevated glycated hemoglobin was 47.34%. In the Poisson multiple regression model analysis with robust variance, poor glycemic control was significantly associated (p<0.05) with the following factors: insulin use (Prevalence Ratio -PR = 2.03), fasting glucose ≤70 and ≥100 mg/dL (PR = 2.0), postprandial glucose ≥180 mg/dL (PR = 1.76), no physical activity (PR = 1.62), the interaction between age group ≤59 years and the time of disease diagnosis >10 years (PR = 1.58), and presence of arterial hypertension (PR = 0.79).
Conclusion. Most users of the reference outpatient clinic with type 2 diabetes had poor glycemic control associated with risk factors that alter glycated hemoglobin and negatively affect the achievement of established glycemic levels.
Joint Military Forces of East-Central Europe in the Light of Selected Political Concepts of the Polish Émigré Milieu
Authors: Zapart Robert 
Published: November 2021

This article attempts to analyse the creation of common armed forces in East-Central Europe on the basis of selected integration concepts of the Polish émigré circles. They considered the notion of consolidating the potentials of countries sharing similar historical experiences as well as a sense of being threatened and protecting similar fundamental values to be part of a larger process of providing the Old Continent with guarantees of security and stable development. From the perspective of international relations at that time, however, none of the concepts of a common security and defence policy could have achieved success, although it could have been considered as one of the alternatives for the development of the process of continental integration, especially if it had been linked to the replenishment of the deficient assets in the potentials of other actors of international relations close to East-Central Europe in terms of development and culture.
Status of Polish Priests in the United States 1956-1977
Authors: Nir Roman 
Published: November 2021

In 1976 the Polish Episcopate made a decision to regulate the status of Polish priests who left for the USA in 1956-1976. In Warsaw, thr work was manages by the Episcopal Secretariat, and in the USA, the coordinating office in Orchard Lake Schools, headed by Rev. Msgr. Alexander Cendrowski. Bishop Wesoły and Rubin from Rome cooperated with the center. On behalf of the American Episcopate, the Secretary General, Archbishop Bernardin, and the head of the Emigration and Tourism Commission Bishop Gracida cooperated.
In the years 1956-1976, 356 priests and religious left Poland from 48 dioceses and 14 religious orders, including 165 priests and 186 religious. October 15, 1977 the status of priests was as follows: incardinated priests 52, religious 56; 16 in the incardination process, 17 emeritus, 7 returned to Poland, 33 had problems with incardination, 56 worked as a guest. The worked the most; 42 in Detroit, 41 in Chicago, 20 in Gary, 18 in Brooklyn and Philadelphia, 15 Buffalo, less than 10 in 18 dioceses It was impossibile to establish the status of the other priests they were suspended, sent to the secular state and entered into marriage.
After 1978 Polish bishops made individual decisions and, in general, they lifted their suspensions and allowed them to work in the USA.
Listy ks. Wincentego Danka do abp. Józefa Bilczewskiego z lat 1900-1919 (część I)
Authors: Wołczański Józef 
Published: November 2021

Niniejsza edycja źródeł historycznych dotyczy listów duchownego archidiecezji lwowskiej obrządku łacińskiego ks. Wincentego Danka (1870-1945) do metropolity lwowskiego abp. Józefa Bilczewskiego (1860-1923). Dokumenty te odnoszą się do lat 1900-1919, a więc niemal całego pontyfikatu lwowskiego hierarchy. Przechowywane są w spuściźnie po metropolicie w Archiwum Archidiecezji Lwowskiej ob. łac. w Krakowie. Nie zachowały się jednak listy abp. Bilczewskiego do ks. Danka. Tym bardziej cenne są te, które stanowią przedmiot niniejszej edycji choćby z tej racji, że nigdy dotąd nie były wykorzystywane w badaniach naukowych. Dodatkowym ich atutem jest zawarta w nich problematyka zabiegów polonijnego duszpasterza w Budapeszcie ks. Danka o zorganizowanie systematycznego duszpasterstwa dla rodaków, a nade wszystko starania o budowę kościoła. Inicjator tej akcji, za aprobatą tak kościelnych i państwowych czynników węgierskich, jak również abp. Bilczewskiego podjął szeroko zakrojoną akcję gromadzenia funduszy i poparcia w środowisku węgierskim i galicyjskim. Nawiązał kontakty z rodami arystokracji węgierskiej spokrewnionej ze sferami polskiego ziemiaństwa, pozyskał względy osób powiązanych z dworem cesarskim w Wiedniu, zdobył zaufanie niektórych członków rządu i parlamentu Austro-Węgier, co miało zaowocować zabezpieczeniem bazy materialnej planowanej inwestycji. Realizacji tak szczytnej idei przeszkodził wybuch I wojny światowej, wskutek czego finalizacja budowy kościoła pw. Najświętszej Maryi Panny Wspomożenia Wiernych doszła do skutku dopiero w 1926 r. Dokonano wówczas poświęcenia świątyni, a jej konsekracja miała miejsce cztery lata później.
A Hospital-Based Study of EGFR and ALK Mutations in Patients with Lung Adenocarcinoma in Odisha
Authors: Parida Prasant Kumar , Dash Sashibhusan 
Published: November 2021

Background: Patients with advanced non-small cell lung cancer (NSCLC) have considerably benefited from the molecular identification of epidermal growth factor receptor (EGFR) and anaplastic lymphoma kinase (ALK) mutations and subsequent targeted therapy against these biomarkers. Few studies have been undertaken in the Indian population on the analysis of both EGFR and ALK mutations in lung adenocarcinoma cases.
Aim and Objectives: The aim of this study was to determine the prevalence of EGFR and ALK mutations in lung adenocarcinoma patients, as well as to link mutational status with age, sex, and smoking history.
Materials and Methods: This single hospital-based retrospective study was conducted at the Department of Medical Oncology, Acharya Harihar Post Graduate Institute of Cancer, Cuttack, on histologically proven lung adenocarcinoma cases over a duration of two years from 01.08.2019 to 31.07.2021.
Results: Out of a total of 164 cases, males comprised 89 (54.26%) of the 164 lung adenocarcinoma cases, while females comprised 75 (45.73%). EGFR mutations were found in 42 (26.75%) of the patients. In 9 cases, the ALK gene rearrangement was also determined to be positive (5.66%). In terms of EGFR and ALK mutations, there was no statistically significant relationship between patient age and gender. (P-value < 0.05). In our research, we found a link between nonsmokers and EGFR and ALK mutations. (P-value <0.05). The deletion of exon 19 (76.19%) was the most prevalent mutation, followed by the exon 21 L858R mutation (14.28%).
Conclusion: This study was found to have a significantly higher rate of EGFR and ALK mutation in the Indian population with adenocarcinoma of lung compared to Western populations. To get the maximum benefit from targeted therapies, all patients of adenocarcinoma of the lung should have mutational testing for EGFR and ALK as part of a broad molecular pannel.
Study on the In vitro and In vivo Antifungal Activities of Nano-silver against Mycoleptodiscus indicus causing Leaf Blight on Lotus in Vietnam
Authors: Hong Hoang Thi Kim , Vu Nguyen Quang Hoang , Hanh Nguyen Thi Ngoc , Ha Tran Thi , Dung Le Quang Tien 
Published: November 2021

Background: Lotus, Nelumbo nucifera Gaertn is Vietnam’s symbol and Buddhism’s flower and plays an essential part in rural Vietnam’s economy as all aspects of lotus could bring benefits to farmers. But, unfortunately, lotus yield in Vietnam is seriously affected by various plant diseases. Among them, leaf blight is currently emerging as one of the primary diseases devastating lotus crops in Vietnam, in which there are large necrotic parts on lotus leaves, flowers and seeds. Methods: Aloe barbadensis extract was used for synthesizing silver nanoparticles. Leaf blight lotus leaves were collected to isolate pathogenic fungi-infection of isolated pathogenic fungi on the healthy lotus and then identify hidden mold by 28S rRNA sequencing. Determination of in vitro minimal inhibition concentration of nano-silver was conducted according to Azizi. The reduction of disease symptoms and biological characteristics of the treated lotus was observed. Result: Morphological analysis and molecular identification of 28S rRNA sequencing showed that the pathogenic microorganism was Mycoleptodiscus indicus (M. indicus). Both in vitro antifungal activity and in vivo treatment of leaf blight lotus using a nano-silver solution showed that 30 ppm of nano-silver was the minimal inhibition concentration (MIC) for totally eradicating M. indicus growth. This was the first time M. indicus was reported to infect and cause leaf blight on a lotus. Previously, M. indicus was a well-known plant pathogen that could cross-kingdom infect humans and animals. Thus, the fact that lotus is widely cultured in Vietnamese rural could increase the chance for M. indicus to spread; hence, this raised the alarm about its potential harm to plants, humans and animals. And, significantly, it revealed nano-silver as a possible approach to prevent M. indicus.