bluuebunny/crossref_metadata_2025_split huggingface dataset:
Conditions for walk-off soliton generation in a multimode fiber
Authors: Zitelli Mario , Mangini Fabio , Ferraro Mario , Sidelnikov Oleg , Wabnitz Stefan 
Published: August 2021

AbstractIt has been recently demonstrated that multimode solitons are unstable objects which evolve, in the range of hundreds of nonlinearity lengths, into stable single-mode solitons carried by the fundamental mode. We show experimentally and by numerical simulations that femtosecond multimode solitons composed by non-degenerate modes have unique properties: when propagating in graded-index fibers, their pulsewidth and energy do not depend on the input pulsewidth, but only on input coupling conditions and linear dispersive properties of the fiber, hence on their wavelength. Because of these properties, spatiotemporal solitons composed by non-degenerate modes with pulsewidths longer than a few hundreds of femtoseconds cannot be generated in graded-index fibers.
Optimal national prioritization policies for hospital care during the SARS-CoV-2 pandemic
Authors: D’Aeth Josh C. , Ghosal Shubhechyya , Grimm Fiona , Haw David , Koca Esma , Lau Krystal , Moret Stefano , Rizmie Dheeya , Deeny Sarah R. , Perez-Guzman Pablo N. , Ferguson Neil , Hauck Katharina , Smith Peter C. , Forchini Giovanni , Wiesemann Wolfram , Miraldo Marisa 
Published: August 2021

AbstractIn response to unprecedented surges in the demand for hospital care during the SARS-CoV-2 pandemic, health systems have prioritized patients with COVID-19 to life-saving hospital care to the detriment of other patients. In contrast to these ad hoc policies, we develop a linear programming framework to optimally schedule elective procedures and allocate hospital beds among all planned and emergency patients to minimize years of life lost. Leveraging a large dataset of administrative patient medical records, we apply our framework to the National Health Service in England and show that an extra 50,750–5,891,608 years of life can be gained compared with prioritization policies that reflect those implemented during the pandemic. Notable health gains are observed for neoplasms, diseases of the digestive system, and injuries and poisoning. Our open-source framework provides a computationally efficient approximation of a large-scale discrete optimization problem that can be applied globally to support national-level care prioritization policies.
Dominant inter‐area oscillation path analysis of power systems with a high penetration of permanent magnet synchronous generator by using network mode energy
Authors: Liu Cheng , Yu Siyao , Zhang Yuchi , Diao Shuo , Zhao Xiaoyang 
Published: August 2021

AbstractIn this study, a network mode energy (NME) method is used to analyse the low‐frequency oscillation (LFO) of a power system with a high penetration of a permanent magnet synchronous generator (PMSG). This method is also utilized to determine the dominant inter‐area oscillation path. NME comes from a network potential energy based on a small signal mode, which includes a generator internal node mode potential energy and a line mode potential energy (LMPE). The exchange process and distribution of NME in the power system containing the PMSG are studied by analysing the composition of LMPE. A sensitivity index is constructed to determine the state variables of the generator and the PMSG, which remarkably influences energy distribution. Then, the path characteristics of LFO are analysed. The dominant inter‐area oscillation paths and energy interaction of the system connecting to the PMSG are determined. The proposed NME can be calculated on the basis of measurement information, and network energy decomposition is carried out using the measured line mode oscillation index. The mechanism of PMSG participating in oscillation is revealed from the network perspective to provide a basis for network‐based regulation. The correctness analysis and simulation of a four‐machine two‐area system with the PMSG and the New England 10‐machine 39‐bus system with the PMSG are carried out.
Hufrehe – Korrektur der Grundkonstitution durch Homöopathie
Authors: Milleder Beatrice 
Published: August 2021

ZusammenfassungUrsachen und Symptome der Hufrehe variieren individuell in weiten Grenzen. Für dauerhafte Abhilfe kann daher nur eine Korrektur der Grundkonstitution des jeweiligen Tieres sorgen. Hierbei ist die klassische Homöopathie von großem Nutzen. Anhand zweier Fallbeispiele wird aufgezeigt, wie durch das richtige konstitutionelle Mittel das erneute Auftreten von Rehe verhindert und die Lebensqualität betroffener Tiere verbessert werden kann.
Validation of the Repetitions in Reserve Rating Scale in Paralympic Powerlifting Athletes
Authors: Neto Frederico Ribeiro , Dorneles Jefferson Rodrigues , Aidar Felipe José , Gonçalves Carlos Wellington , Veloso João , Costa Rodrigo Rodrigues Gomes 
Published: August 2021

AbstractThe present study aimed to validate the perceived exertion scale based on the repetitions in reserve (RIR) of Paralympic Powerlifting (PP) athletes. Twenty-one PP athletes were assessed in the one-maximum repetition test (1RM) of the bench press exercise, maximum repetition strength tests with loads corresponding to 90, 85, 80, and 75% of 1RM, and 4-repetitions strength tests (4-repST) with 100, 90, 85, 80, and 75% of the 1RM. The RIR scale was assessed after each set of the 4-repST and compared to the 1RM and maximum strength tests. For criterion validity, the total estimated repetition was significantly lower compared to the maximum strength test repetitions in the lower scores of the RIR scale (median=7.0 vs. 9.0 for 75% of 1RM). The total estimated repetition correlation with maximum strength was very high and significant (ICC=0.91). Using the Bland and Altman method, the difference between means was 0.9 reps, and the interval around differences was 6.4 reps. For construct validity, and the RIR scale presented high correlation with 1RM intensities (rho=0.86, p≤0.05). The RIR scale was validated and coaches and sports trainers can use this monitoring tool to ensure submaximal loads when improving lift technique, which is extremely rigorous in PP.
Alterações hematológicas após implante de matriz óssea desmineralizada caprina em modelo de defeito ulnar crítico em coelhos
Authors: Alimi Olawale Alimi , Abubakar Adamu Abdul , Yakubu Abubakar Sadiq , Shehu Sani Abdullahi , Abdulkadir Salman Zubairu , Oviawe Ekaete Ime 
Published: August 2021

Resumo
Objetivo Diversos modelos animais têm sido usados em estudos sobre enxertos ósseos e o tratamento de fraturas, mas as respostas hematológicas são raramente relatadas. Este estudo descreveu as alterações hematológicas observadas em coelhos submetidos a xenoenxertos de matriz óssea desmineralizada caprina (MODC).
Métodos Vinte e quatro (24) coelhos machos (2,5 ± 0,5 kg) foram adquiridos para este estudo e divididos aleatoriamente em três grupos: enxerto ósseo autólogo (EOA); controle negativo sem preenchimento (SP) e matriz óssea desmineralizada caprina (MODC). Amostras de sangue foram coletadas por punção cardíaca sob anestesia com xilazina-quetamina no dia 0 (para estabelecimento dos valores basais) e aos dias 28 e 56 após a cirurgia; essas amostras foram submetidas à análise manual em até 2 horas após a coleta. A análise estatística foi composta por análise de variância (ANOVA) de dois fatores com medidas repetidas, e o valor de p < 0,05 foi considerado significativo.
Resultados Houve uma diferença geral significativa nos números de leucócitos totais (p = 0,0043), neutrófilos (p < 0,0001), monócitos (p = 0,0184) e hemácias (p = 0,003), na concentração de hemoglobina (p < 0,0001) e no hematócrito (p < 0,0001) ao longo dos dias e entre os grupos de tratamento. No entanto, não houve diferença global significativa no número de linfócitos (p = 0,4923), basófilos (p = 0,4183) e eosinófilos (p = 0,4806) entre os dias.
Conclusão A resposta ao enxerto de MODC em coelhos é, portanto, caracterizada por leucocitose intensa com neutrofilia, linfocitose e monocitose no 28° dia após o procedimento. Esses dados podem basear a utilização da hematologia no monitoramento da resposta corporal em modelos animais de enxerto ósseo.
Tratamento de fraturas acetabulares de duas colunas por dupla via extrapélvica: Três casos clínicos
Authors: Boavida João , Ribeiro Paulo Gil , Costa Paulo , Quintas Catarina , Moura Diogo Lino , Figueiredo António 
Published: August 2021

ResumoAs fraturas de duas colunas do acetábulo segundo a classificação de Letournel são das mais comuns em frequência, indicação e complexidade cirúrgica. Estas resultam essencialmente de mecanismos de compressão lateral e caracterizam-se por originarem um acetábulo desconectado do esqueleto axial. O seu tratamento cirúrgico pode incluir: abordagem anterior ou posterior isolada; combinadas, no mesmo tempo cirúrgico ou não; ou abordagens alargadas. Os autores apresentam outra opção cirúrgica com associação de via de Kocher-Langenbeck e abordagem da crista ilíaca simultânea e no mesmo posicionamento (decúbito lateral) com base nos três primeiros casos clínicos realizados e seus resultados clínicos e imagiológicos. Para além da apresentação dos casos, é feita uma descrição dos três fragmentos característicos deste tipo de fraturas acetabulares, da via de abordagem e da sequência de redução realizada. Pelos resultados obtidos e vantagens associadas, os autores acreditam que a adição da abordagem da crista ilíaca à via de Kocher-Langenbeck pode ser uma opção muito atrativa a ter em conta no tratamento cirúrgico de fraturas de duas colunas do acetábulo devidamente selecionadas.
Workplace Violence in Emergency Departments in Turkey
Authors: Sabak Mustafa , Al-Hadidi Ameer , Oktay Mehmet Murat , Al Behcet , Kazaz Tanyeli , Kowalenko Terry , Hakmeh Wael 
Published: August 2021

Abstract
Background Studies on workplace violence against physicians in emergency departments (EDs) in Turkey are lacking.
Methods To describe the frequency and types of workplace violence, a 34-question online survey of the past 12 months was sent to physicians working in EDs in Turkey. Types of violence were categorized as verbal threats, physical assaults, confrontation, stalking, and sexual harassment.
Results A total of 366 physicians completed the survey; 4 were excluded (minimum 20 hours/week). Sixty-two percent of respondents were men. Ninety-nine percent reported verbal abuse and 54% reported physical violence. Family members, not patients, were the most common perpetrators of every form of workplace violence. Hospitals limiting the number of visitors and loitering had 14% reduction in physical threats. Only 23% of respondents indicated that their hospital offered information about preventing and managing workplace violence even though 86% noted interest. Only 1% never had fear, even though 89% indicated they had security staff. Over 89% felt that hospital security was lacking in number and ability to protect. For 82%, workplace violence affected their ability to provide patient care. Ninety percent indicated that current laws do not adequately protect them. There was also no statistically significant difference in any type of workplace violence based on the timing or length of shifts, type of hospital, or number of hours worked. Of all types of violence reported, only stalking demonstrated a statistically significant difference between men and women.
Conclusion Workplace violence is a real danger for physicians working in EDs in Turkey, similar to other countries, demonstrating that this problem transcends borders. Further studies should assess root causes of violent behaviors of patients and their visitors, as well as possible (administrative, social, and legal) mechanisms to minimize such violence. Hospitals that limited the number of visitors and empowered security officers were associated with decreased violence.
Turning Problems into Opportunities: How to Resume Urological Elective Surgery Using a Scoring System during COVID-19 Outbreak
Authors: Chavarriaga Julian , Lopez-Ramos Hugo , Prada Juan , Fernandez Nicolas 
Published: August 2021

Abstract
Objective Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), which is the largest pandemic in the last century and has created a health care crisis worldwide. Contingency plans have led to put on hold all urological elective surgeries. The aim of the present article is to report the adaptation of the Medically Necessary Time-Sensitive (MeNTS) scoring system to triage patients who were awaiting urological elective surgery during the COVID-19 pandemic.
Methods The present study was conducted as a part of a necessary transition of care delivery at a tertiary care institution in order to re-establish urological elective surgery. We triaged all urological elective surgeries with the MeNTS instrument and proposed a cutoff value of 45 points to avoid complications in the COVID-19 crisis while resuming elective procedures.
Results A total of 91 patients awaiting elective urological surgery pending to be rescheduled were identified. Their median age was 60.5 years old (interquartile range [IQR]: 46–93). Twenty-five patients were American Society of Anesthesiologists (ASA) class I, 51 (56%) were class II, and 12 (13%) were class III. The median MeNTS score was 42 points (IQR: 36–59). Twenty-nine patients had a MeNTS score > 45 and were advised to postpone their surgery. Sixty-two had a score ≤ 45 and were gradually rescheduled.
Conclusions The present study may have practical implications regarding the selection of urological elective surgeries in the challenging health care situation caused by the COVID-19 pandemic. Our real-life data showed us that 32% of our procedures must be postponed, and 68% could be carefully considered and gradually rescheduled for surgery.
Platelet Surface Protein Expression and Reactivity upon TRAP Stimulation after BNT162b2 Vaccination
Authors: Klug Melissa , Lazareva Olga , Kirmes Kilian , Rosenbaum Marc , Lukas Marina , Weidlich Simon , Spinner Christoph D. , von Scheidt Moritz , Gosetti Rosanna , Baumbach Jan , Ruland Jürgen , Condorelli Gianluigi , Laugwitz Karl-Ludwig , List Markus , Bernlochner Isabell , Bongiovanni Dario 
Published: August 2021

AbstractSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection induces a coagulopathy characterized by platelet activation and a hypercoagulable state with an increased incidence of cardiovascular events. The viral spike protein S has been reported to enhance thrombosis formation, stimulate platelets to release procoagulant factors, and promote the formation of platelet–leukocyte aggregates even in absence of the virus. Although SARS-CoV-2 vaccines induce spike protein overexpression to trigger SARS-CoV-2-specific immune protection, thrombocyte activity has not been investigated in this context. Here, we provide the first phenotypic platelet characterization of healthy human subjects undergoing BNT162b2 vaccination. Using mass cytometry, we analyzed the expression of constitutive transmembrane receptors, adhesion proteins, and platelet activation markers in 12 healthy donors before and at five different time points within 4 weeks after the first BNT162b2 administration. We measured platelet reactivity by stimulating thrombocyte activation with thrombin receptor-activating peptide. Activation marker expression (P-selectin, LAMP-3, LAMP-1, CD40L, and PAC-1) did not change after vaccination. All investigated constitutive transmembrane proteins showed similar expressions over time. Platelet reactivity was not altered after BNT162b2 administration. Activation marker expression was significantly lower compared with an independent cohort of mild symptomatic COVID-19 patients analyzed with the same platform. This study reveals that BNT162b2 administration does not alter platelet protein expression and reactivity.
Reflections on integrated research from community engagement in peatland restoration
Authors: Fleming A. , Agrawal S. , Dinomika  , Fransisca Y. , Graham L. , Lestari S. , Mendham D. , O’Connell D. , Paul B. , Po M. , Rawluk A. , Sakuntaladewi N. , Winarno B. , Yuwati T. W. 
Published: August 2021

AbstractCommunity engagement and integrated research are key approaches to solving complex socio-ecological challenges. This paper describes the experience of bringing together a team of natural and social scientists from Australia and Indonesia in the ‘Gambut Kita’ (translated as ‘Our Peat’) project. Gambut Kita aims to produce new knowledge and support efforts to successfully, and equitably, restore Indonesia’s tropical peatlands and ensure that livelihoods can be maintained on restored (rewetted) landscapes. The paper focuses on experiences of using community engagement for integrated research. It discusses three community engagement approaches used in the project—resilience, adaptation pathways and transformation approach (RAPTA), participatory rural appraisal (PRA), and community-led analysis and planning (CLAP). It also describes the qualitative analysis of 14 interviews with the project team of lessons learned in community engagement for integrated research. ‘Criteria for success’ from the literature on international development projects is used to assess progress. The findings highlight the specific complexities of working across countries and cultures. Successful community engagement is not so much about the ‘tool’ but about the trust, agency, and support to change. The tools do, however, have different strengths. PRA and CLAP can build deep community understanding and relationships. RAPTA has strengths in framing visions and pathways to the future, systems thinking, anticipatory learning, and taking a cross-scale systems view which is required to solve many of the problems manifesting at local or community scales. Similarly, success in integrated research is not just about individuals, but structures (e.g. explicit process) and infrastructure (e.g. access to technology). These findings suggest that integrated research needs special considerations in terms of design, and these relate across scales to individual researchers as well as teams, leaders and organisations. Integrated research projects need careful, inclusive, iterative management with a lot of interaction to learn from each other, build a common vision, achieve clarity of roles, and share emerging findings.
Molecular dynamic study of alcohol-based deep eutectic solvents
Authors: Ferreira Elisabete S. C. , Voroshylova Iuliia V. , Figueiredo Nádia M. , Cordeiro M. Natália D. S. 
Published: August 2021

The applicability of deep eutectic solvents is determined by their physicochemical properties. In turn, the properties of eutectic mixtures are the result of the components’ molar ratio and chemical composition. Owing to the relatively low viscosities displayed by alcohol-based deep eutectic solvents (DESs), their application in industry is more appealing. Modeling the composition–property relationships established in polyalcohol-based mixtures is crucial for both understanding and predicting their behavior. In this work, a physicochemical property–structure comparison study is made between four choline chloride polyalcohol-based DESs, namely, ethaline, propeline, propaneline, and glyceline. Physicochemical properties obtained from molecular dynamic simulations are compared to experimental data, whenever possible. The simulations cover the temperature range from 298.15 to 348.15 K. The simulated and literature experimental data are generally in good agreement for all the studied DESs. Structural properties, such as radial and spatial distribution functions, coordination numbers, hydrogen bond donor (HBD)–HBD aggregate formation, and hydrogen bonding are analyzed in detail. The higher prevalence of HBD:HBD and HBD:anion hydrogen bonds is likely to be the major reason for the relatively high density and viscosity of glyceline as well as for lower DES self-diffusions.
Trade-offs among transport, support, and storage in xylem from shrubs in a semiarid chaparral environment tested with structural equation modeling
Authors: Pratt R. B. , Jacobsen A. L. , Percolla M. I. , De Guzman M. E. , Traugh C. A. , Tobin M. F. 
Published: August 2021

Significance
Plant vascular systems play a central role in global water and carbon cycles and drought resistance. These vascular systems perform multiple functions that affect the fitness of plants, and trade-offs are present among these functions. Some trade-offs are well established, but studies have not examined the full suite of functions of these complex systems. Here, we used a powerful multivariate method, structural equation modeling, to test hypotheses about the trade-offs that govern this vital and globally important tissue. We show that xylem traits are broadly governed by trade-offs related to transport, mechanical support, and storage, which are rooted in cellular structure, and that the level of dehydration experienced by plants in the field exerts a strong influence over these relationships.
An image-computable model of how endogenous and exogenous attention differentially alter visual perception
Authors: Jigo Michael , Heeger David J. , Carrasco Marisa 
Published: August 2021

Significance
Visual attention alters perception. Endogenous (voluntary) and exogenous (involuntary) spatial attention shape perception by prioritizing some visual information and ignoring others. Each attention type induces different perceptual consequences. Endogenous attention flexibly optimizes the visibility of fine-grain or coarse-scale visual features, whereas exogenous attention inflexibly enhances fine details, even when detrimental to perception. The computations that govern these differences are unknown. We developed a computational model that predicts human behavior and these distinct attentional effects directly from visual displays used in previous experiments. At the model’s core, each attention type adjusts sensory processing with different selectivity across visual detail. The model explains several phenomena, including uniform improvements induced by endogenous attention and visual improvements and impairments induced by exogenous attention.
Manifold alignment for heterogeneous single-cell multi-omics data integration using Pamona
Authors: Cao Kai , Hong Yiguang , Wan Lin 
Published: August 2021

Abstract

Motivation
Single-cell multi-omics sequencing data can provide a comprehensive molecular view of cells. However, effective approaches for the integrative analysis of such data are challenging. Existing manifold alignment methods demonstrated the state-of-the-art performance on single-cell multi-omics data integration, but they are often limited by requiring that single-cell datasets be derived from the same underlying cellular structure.

Results
In this study, we present Pamona, a partial Gromov-Wasserstein distance-based manifold alignment framework that integrates heterogeneous single-cell multi-omics datasets with the aim of delineating and representing the shared and dataset-specific cellular structures across modalities. We formulate this task as a partial manifold alignment problem and develop a partial Gromov-Wasserstein optimal transport framework to solve it. Pamona identifies both shared and dataset-specific cells based on the computed probabilistic couplings of cells across datasets, and it aligns cellular modalities in a common low-dimensional space, while simultaneously preserving both shared and dataset-specific structures. Our framework can easily incorporate prior information, such as cell type annotations or cell-cell correspondence, to further improve alignment quality. We evaluated Pamona on a comprehensive set of publicly available benchmark datasets. We demonstrated that Pamona can accurately identify shared and dataset-specific cells, as well as faithfully recover and align cellular structures of heterogeneous single-cell modalities in a common space, outperforming the comparable existing methods.

Availabilityand implementation
Pamona software is available at https://github.com/caokai1073/Pamona.

Supplementary information
Supplementary data are available at Bioinformatics online.