bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Novel Artificial Neuron-Like Gas Sensor Constructed from CuS Quantum Dots/Bi2S3 Nanosheets
Authors: Chen Xinwei , Wang Tao , Shi Jia , Lv Wen , Han Yutong , Zeng Min , Yang Jianhua , Hu Nantao , Su Yanjie , Wei Hao , Zhou Zhihua , Yang Zhi , Zhang Yafei 
Published: December 2021

AbstractReal-time rapid detection of toxic gases at room temperature is particularly important for public health and environmental monitoring. Gas sensors based on conventional bulk materials often suffer from their poor surface-sensitive sites, leading to a very low gas adsorption ability. Moreover, the charge transportation efficiency is usually inhibited by the low defect density of surface-sensitive area than that in the interior. In this work, a gas sensing structure model based on CuS quantum dots/Bi2S3 nanosheets (CuS QDs/Bi2S3 NSs) inspired by artificial neuron network is constructed. Simulation analysis by density functional calculation revealed that CuS QDs and Bi2S3 NSs can be used as the main adsorption sites and charge transport pathways, respectively. Thus, the high-sensitivity sensing of NO2 can be realized by designing the artificial neuron-like sensor. The experimental results showed that the CuS QDs with a size of about 8 nm are highly adsorbable, which can enhance the NO2 sensitivity due to the rich sensitive sites and quantum size effect. The Bi2S3 NSs can be used as a charge transfer network channel to achieve efficient charge collection and transmission. The neuron-like sensor that simulates biological smell shows a significantly enhanced response value (3.4), excellent responsiveness (18 s) and recovery rate (338 s), low theoretical detection limit of 78 ppb, and excellent selectivity for NO2. Furthermore, the developed wearable device can also realize the visual detection of NO2 through real-time signal changes.
Islet-on-a-chip for the study of pancreatic β-cell function
Authors: Rodríguez-Comas Júlia , Ramón-Azcón Javier 
Published: December 2021

AbstractDiabetes mellitus is a significant public health problem worldwide. It encompasses a group of chronic disorders characterized by hyperglycemia, resulting from pancreatic islet dysfunction or as a consequence of insulin-producing β-cell death. Organ-on-a-chip platforms have emerged as technological systems combining cell biology, engineering, and biomaterial technological advances with microfluidics to recapitulate a specific organ’s physiological or pathophysiological environment. These devices offer a novel model for the screening of pharmaceutical agents and to study a particular disease. In the field of diabetes, a variety of microfluidic devices have been introduced to recreate native islet microenvironments and to understand pancreatic β-cell kinetics in vitro. This kind of platforms has been shown fundamental for the study of the islet function and to assess the quality of these islets for subsequent in vivo transplantation. However, islet physiological systems are still limited compared to other organs and tissues, evidencing the difficulty to study this “organ” and the need for further technological advances. In this review, we summarize the current state of islet-on-a-chip platforms that have been developed so far. We recapitulate the most relevant studies involving pancreatic islets and microfluidics, focusing on the molecular and cellular-scale activities that underlie pancreatic β-cell function.
Does the coronavirus disease 2019 (COVID-19) vaccination rate among healthcare personnel reflect their community? An evaluation of a multistate healthcare system
Authors: Fakih Mohamad G. , Fogel Richard , Ottenbacher Allison , Miller Collin , Winegar Angela L. , Price Shanda C. , Masoudi Fredrick A. , Cacchione Joseph 
Published: December 2021

AbstractCoronavirus disease 2019 (COVID-19) vaccination rates of a large health system reflected their respective service areas but varied by work role. Nurse vaccination rates were higher (56.9%) and rates among nursing support personnel were lower (38.6%) than those of their communities (51.7%; P < .001). Physician vaccination rates were highest (71.6%) and were not associated with community vaccination levels.
On Being a Fan and on Fanhood and Its Implications for Defeating the Moral Sceptic
Authors: Superson Anita M. 
Published: December 2021

AbstractI employ the notion of fanhood to object to David Gauthier's Dependency Thesis, according to which, if a disposition is rationally required to adopt, so too are the acts expressing it. I first establish that fanhood is a commitment relevantly similar to a moral commitment. I then argue that, because genuine fanhood characteristically issues in inherently irrational behaviours in the form of ‘luck charms,’ or, superstitious practices fans believe will help their team win, it poses a decisive objection to the Dependency Thesis, thereby eliminating a promising attempt to defeat the moral sceptic.
Evidence in favor of a strategy-based model for English pronunciation instruction
Authors: Sardegna Veronica G. 
Published: December 2021

AbstractResearch has increasingly demonstrated that pronunciation difficulties in English can seriously affect learners’ intelligibility and ability to comprehend spoken English. It is thus crucial that we find ways of helping learners of English become more intelligible. In this talk, I present compelling research evidence in support of a strategy-based pronunciation instruction model, and uncover individual learner, teacher, and instructional variables affecting long-term improvement. Findings from my published and ongoing studies involving different groups of learners and teachers highlight the critical role of teachers in self-regulated learning, and suggest the need for methodological refinements to the model. The results show that students’ self-regulated efforts at learning can be further enhanced and supported if combined with goal-setting and awareness-raising activities, online speech models and resources, video-recordings to assess progress, guided reflections on oral assignments, ongoing feedback, and re-assessments of goals after improvement. I conclude the talk with a discussion of these methodological refinements and possible avenues for future research.
Rigid–flexible coupling dynamics analysis with joint clearance for a 5-DOF hybrid polishing robot
Authors: Guo Feng , Cheng Gang , Wang Shilin , Li Jun 
Published: December 2021

SUMMARYConsidering the polishing requirements for high-precision aspherical optical mirrors, a hybrid polishing robot composed of a serial–parallel manipulator and a dual rotor grinding system is proposed. Firstly, based on the kinematics of serial components, the equivalent load model for the parallel manipulator is established. Then, the elastodynamic model of kinematic branched-chains of the parallel manipulator is established by using the spatial beam element, and the rigid–flexible coupling dynamic model of the polishing robot is obtained with Kineto-elasto dynamics theory. Further, considering the dynamic properties of the joint clearance, the rigid–flexible coupling dynamic model with the joint clearance for the polishing robot is established. Finally, the equivalent load distribution of the parallel manipulator is analyzed, and the effect of the branched-chain elasticity and joint clearance on the motion error of the polishing robot is studied. This article provides a theoretical basis for improving the motion accuracy and dynamic performance of the hybrid polishing robot.
Compounding and complementary carnivores: Australian bird species eaten by the introduced European red fox Vulpes vulpes and domestic cat Felis catus
Authors: WOINARSKI JOHN C.Z. , STOBO-WILSON ALYSON M. , CRAWFORD HEATHER M. , DAWSON STUART J. , DICKMAN CHRIS R. , DOHERTY TIM S. , FLEMING PATRICIA A. , GARNETT STEPHEN T. , GENTLE MATTHEW N. , LEGGE SARAH M. , NEWSOME THOMAS M. , PALMER RUSSELL , REES MATTHEW W. , RITCHIE EUAN G. , SPEED JAMES , STUART JOHN-MICHAEL , THOMPSON EILYSH , TURPIN JEFF , MURPHY BRETT P. 
Published: December 2021

Abstract
Two introduced carnivores, the European red fox Vulpes vulpes and domestic cat Felis catus, have had extensive impacts on Australian biodiversity. In this study, we collate information on consumption of Australian birds by the fox, paralleling a recent study reporting on birds consumed by cats. We found records of consumption by foxes on 128 native bird species (18% of the non-vagrant bird fauna and 25% of those species within the fox’s range), a smaller tally than for cats (343 species, including 297 within the fox’s Australian range, a subset of that of the cat). Most (81%) bird species eaten by foxes are also eaten by cats, suggesting that predation impacts are compounded. As with consumption by cats, birds that nest or forage on the ground are most likely to be consumed by foxes. However, there is also some partitioning, with records of consumption by foxes but not cats for 25 bird species, indicating that impacts of the two predators may also be complementary. Bird species ≥3.4 kg were more likely to be eaten by foxes, and those <3.4 kg by cats. Our compilation provides an inventory and describes characteristics of Australian bird species known to be consumed by foxes, but we acknowledge that records of predation do not imply population-level impacts. Nonetheless, there is sufficient information from other studies to demonstrate that fox predation has significant impacts on the population viability of some Australian birds, especially larger birds, and those that nest or forage on the ground.
Lobbying Beyond the Legislature: Challenges and Biases in Women's Organizations’ Participation in Rulemaking
Authors: English Ashley 
Published: December 2021

AbstractThis study, which is based on a survey of women's organizations’ staff members, answers two previously unexamined questions about women's groups’ participation in the rulemaking process: (1) How do women's organizations participate? (2) What are the characteristics of the women's organizations that are the most likely to participate? About one-quarter (27%) of women's organizations reported that they lobby rulemakers, often using relatively low-cost methods, such as submitting comments or signing on to comments written by coalitions or like-minded groups. Women's organizations with large staffs that are structured the most like political insiders or influential economic interest groups were the most likely to participate in the process, potentially biasing participation in favor of relatively advantaged subgroups of women. Together, these results suggest that although rulemaking presents unique opportunities to represent women, the most marginalized women may be underrepresented during rulemaking debates.
Carbon Geochemistry of the Active Serpentinization Site at the Wadi Tayin Massif: Insights From the ICDP Oman Drilling Project: Phase II
Authors: Ternieten Lotta , Früh‐Green Gretchen L. , Bernasconi Stefano M. 
Published: December 2021

AbstractA large part of the hydrated oceanic lithosphere consists of serpentinites exposed in ophiolites. Serpentinites constitute reactive chemical and thermal systems and potentially represent an effective sink for CO2. Understanding carbonation mechanisms within ophiolites are almost exclusively based on studies of outcrops, which can limit the interpretation of fossil hydrothermal systems. We present stable and radiogenic carbon isotope data that provide insights into the isotopic trends and fluid evolution of peridotite carbonation in ICDP Oman Drilling Project drill holes BA1B (400‐m deep) and BA3A (300‐m deep). Geochemical investigations of the carbonates in serpentinites indicate formation in the last 50 kyr, implying a distinctly different phase of alteration than the initial oceanic hydration and serpentinization of the Samail Ophiolite. The oldest carbonates (∼31 to >50 kyr) are localized calcite, dolomite, and aragonite veins, formed between 26°C and 43°C and related to focused fluid flow. Subsequent pervasive small amounts of dispersed carbonate precipitated in the last 1,000 years. Macroscopic brecciation and veining of the peridotite indicate that carbonation is influenced by tectonic features allowing infiltration of fluids over extended periods and at different structural levels such as along fracture planes and micro‐fractures and grain boundaries, causing large‐scale hydration of the ophiolite. The formation of dispersed carbonate is related to percolating fluids with δ18O lower than modern ground and meteoric water. Our study shows that radiocarbon investigations are an essential tool to interpret the carbonation history and that stable oxygen and carbon isotopes alone can result in ambiguous interpretations.
Convection Initiation at a Coastal Rainfall Hotspot in South China: Synoptic Patterns and Orographic Effects
Authors: Bai Lanqiang , Chen Guixing , Huang Yipeng , Meng Zhiyong 
Published: December 2021

AbstractThis study documents the detailed features and processes of convection initiation (CI) at a coastal rainfall hotspot in South China, with emphasis on the typical meteorological conditions and effects of small‐scale orography. The CI occurrences are identified using high‐quality radar mosaics during 7‐year warm seasons. They tend to maximize in low‐lying areas adjacent to coastal small‐scale mountains rather than on the windward slopes of major mountains as previously expected. The genesis of the coastal convection exhibits a remarkable diurnal peak in the early afternoon and mostly occurs on the days of low‐level southwesterlies with a jet‐nose structure in offshore region. These onshore flows enhance the low‐level moistening and convergence on coasts. The characteristic synoptic patterns become common after the onset of summer monsoon, suggesting the key role of monsoonal flows in triggering coastal convection. Driven by the atmospheric conditions of the dominant synoptic pattern, quasi‐idealized numerical simulations demonstrate that the coastal small‐scale mountains disturb the low‐level onshore flow and produce multiple enhanced convergent zones downstream of the mountains. The induced local variations in upward motion and moisture pooling explain the CI occurrences that are located close to these small‐scale mountains. When these mountains are artificially removed in the simulation, convection preferentially initiates on the windward slopes of major mountains as expected. The findings suggest that the small‐scale orography can strongly regulate the local patterns of CI hotspot through disturbing low‐level onshore flow. An explicit resolving of the small‐scale coastal orography is warranted to improve the modeling of local severe weather.
Planetary Boundary Layer Height Modulates Aerosol—Water Vapor Interactions During Winter in the Megacity of Delhi
Authors: S. Raj Subha , Krüger Ovid O. , Sharma Amit , Panda Upasana , Pöhlker Christopher , Walter David , Förster Jan‐David , Singh Rishi Pal , S. Swetha , Klimach Thomas , Darbyshire Eoghan , Martin Scot T. , McFiggans Gordon , Coe Hugh , Allan James , R. Ravikrishna , Soni Vijay Kumar , Su Hang , Andreae Meinrat O. , Pöschl Ulrich , Pöhlker Mira L. , Gunthe Sachin S. 
Published: December 2021

AbstractThe Indo‐Gangetic Plain (IGP) is one of the dominant sources of air pollution worldwide. During winter, the variations in planetary boundary layer (PBL) height, driven by a strong radiative thermal inversion, affect the regional air pollution dispersion. To date, measurements of aerosol‐water vapor interactions, especially cloud condensation nuclei (CCN) activity, are limited in the Indian subcontinent, causing large uncertainties in radiative forcing estimates of aerosol‐cloud interactions. We present the results of a one‐month field campaign (February‐March 2018) in the megacity, Delhi, a significant polluter in the IGP. We measured the composition of fine particulate matter (PM1) and size‐resolved CCN properties over a wide range of water vapor supersaturations. The analysis includes PBL modeling, backward trajectories, receptor models and fire spots to elucidate the influence of PBL and air mass origins on aerosols. The aerosol properties depended strongly on PBL height and a simple power‐law fit could parameterize the observed correlations of PM1 mass, aerosol particle number and CCN number with PBL height, indicating PBL induced changes in aerosol accumulation. The low inorganic mass fractions, low aerosol hygroscopicity and high externally mixed weakly CCN‐active particles under low PBL height (100 m) indicated the influence of PBL on aerosol aging processes. In contrast, aerosol properties did not depend strongly on air mass origins or wind direction, implying that the observed aerosol and CCN are from local emissions. An error function could parameterize the relationship between CCN number and supersaturation throughout the campaign.
Reconciling Assumptions in Bottom‐Up and Top‐Down Approaches for Estimating Aerosol Emission Rates From Wildland Fires Using Observations From FIREX‐AQ
Authors: Wiggins E. B. , Anderson B. E. , Brown M. D. , Campuzano‐Jost P. , Chen G. , Crawford J. , Crosbie E. C. , Dibb J. , DiGangi J. P. , Diskin G. S. , Fenn M. , Gallo F. , Gargulinski E. M. , Guo H. , Hair J. W. , Halliday H. S. , Ichoku C. , Jimenez J. L. , Jordan C. E. , Katich J. M. , Nowak J. B. , Perring A. E. , Robinson C. E. , Sanchez K. J. , Schueneman M. , Schwarz J. P. , Shingler T. J. , Shook M. A. , Soja A. J. , Stockwell C. E. , Thornhill K. L. , Travis K. R. , Warneke C. , Winstead E. L. , Ziemba L. D. , Moore R. H. 
Published: December 2021

AbstractAccurate fire emissions inventories are crucial to predict the impacts of wildland fires on air quality and atmospheric composition. Two traditional approaches are widely used to calculate fire emissions: a satellite‐based top‐down approach and a fuels‐based bottom‐up approach. However, these methods often considerably disagree on the amount of particulate mass emitted from fires. Previously available observational datasets tended to be sparse, and lacked the statistics needed to resolve these methodological discrepancies. Here, we leverage the extensive and comprehensive airborne in situ and remote sensing measurements of smoke plumes from the recent Fire Influence on Regional to Global Environments and Air Quality (FIREX‐AQ) campaign to statistically assess the skill of the two traditional approaches. We use detailed campaign observations to calculate and compare emission rates at an exceptionally high‐resolution using three separate approaches: top‐down, bottom‐up, and a novel approach based entirely on integrated airborne in situ measurements. We then compute the daily average of these high‐resolution estimates and compare with estimates from lower resolution, global top‐down and bottom‐up inventories. We uncover strong, linear relationships between all of the high‐resolution emission rate estimates in aggregate, however no single approach is capable of capturing the emission characteristics of every fire. Global inventory emission rate estimates exhibited weaker correlations with the high‐resolution approaches and displayed evidence of systematic bias. The disparity between the low‐resolution global inventories and the high‐resolution approaches is likely caused by high levels of uncertainty in essential variables used in bottom‐up inventories and imperfect assumptions in top‐down inventories.
Failure Probability Analysis of Levees Affected by Mammal Bioerosion
Authors: Balistrocchi Matteo , Moretti Giovanni , Ranzi Roberto , Orlandini Stefano 
Published: December 2021

AbstractMammal bioerosion is an emergent threat to the functionality of levees. In the present paper, the problem of assessing the failure probability of levees affected by mammal bioerosion is addressed. A fully bivariate description of peak flow discharge and flood duration is combined with a deterministic unsteady seepage flow model to obtain a suitable model of variably disturbed levee response to the observed natural variability of floods. Monte Carlo analysis is also implemented to evaluate the epistemic uncertainty connected to the description of the river system. The obtained model is tested with respect to a real‐world levee located along the Secchia River in northern Italy, which underwent a disastrous failure caused by mammal bioerosion in 2014. The convex linear combination of two Archimedean copulas is found to fit the empirical dependence structure between peak flow discharge and flood duration. The reliability of the unsteady seepage flow model is tested against detailed numerical simulations of the seepage occurring through the levee body. A limit state function is obtained by comparing the maximum extent of the seepage front to the distance between the den end and the riverside levee slope, and the corresponding levee safety and failure regions are delimited. Results obtained from the developed model reveal a significant impact of mammal dens located near the levee crest in terms of failure probability and related return period. This impact is consistent with failures observed in the study area.
Regulation of the EphA2 receptor intracellular region by phosphomimetic negative charges in the kinase-SAM linker
Authors: Lechtenberg Bernhard C. , Gehring Marina P. , Light Taylor P. , Horne Christopher R. , Matsumoto Mike W. , Hristova Kalina , Pasquale Elena B. 
Published: December 2021

AbstractEph receptor tyrosine kinases play a key role in cell-cell communication. Lack of structural information on the entire multi-domain intracellular region of any Eph receptor has hindered understanding of their signaling mechanisms. Here, we use integrative structural biology to investigate the structure and dynamics of the EphA2 intracellular region. EphA2 promotes cancer malignancy through a poorly understood non-canonical form of signaling involving serine/threonine phosphorylation of the linker connecting its kinase and SAM domains. We show that accumulation of multiple linker negative charges, mimicking phosphorylation, induces cooperative changes in the EphA2 intracellular region from more closed to more extended conformations and perturbs the EphA2 juxtamembrane segment and kinase domain. In cells, linker negative charges promote EphA2 oligomerization. We also identify multiple kinases catalyzing linker phosphorylation. Our findings suggest multiple effects of linker phosphorylation on EphA2 signaling and imply that coordination of different kinases is necessary to promote EphA2 non-canonical signaling.
Modulation of dopamine tone induces frequency shifts in cortico-basal ganglia beta oscillations
Authors: Iskhakova L. , Rappel P. , Deffains M. , Fonar G. , Marmor O. , Paz R. , Israel Z. , Eitan R. , Bergman H. 
Published: December 2021

AbstractΒeta oscillatory activity (human: 13–35 Hz; primate: 8–24 Hz) is pervasive within the cortex and basal ganglia. Studies in Parkinson’s disease patients and animal models suggest that beta-power increases with dopamine depletion. However, the exact relationship between oscillatory power, frequency and dopamine tone remains unclear. We recorded neural activity in the cortex and basal ganglia of healthy non-human primates while acutely and chronically up- and down-modulating dopamine levels. We assessed changes in beta oscillations in patients with Parkinson’s following acute and chronic changes in dopamine tone. Here we show beta oscillation frequency is strongly coupled with dopamine tone in both monkeys and humans. Power, coherence between single-units and local field potentials (LFP), spike-LFP phase-locking, and phase-amplitude coupling are not systematically regulated by dopamine levels. These results demonstrate that beta frequency is a key property of pathological oscillations in cortical and basal ganglia networks.