bluuebunny/crossref_metadata_2025_split huggingface dataset:
Phytosociological survey of the desert vegetation of Sinai, Egypt
Authors: Hatim Mohamed Z. , Janssen John A. M. , Pätsch Ricarda , Shaltout Kamal , Schaminée Joop H. J. 
Published: November 2021

AbstractAimsAlthough Sinai is a global hotspot for desert vegetation, there is no well‐documented overview of the Sinai vegetation. We aim to provide a phytosociological overview of Sinai desert vegetation based on an extensive database and formal classification. We further aim to describe the vegetation communities and provide information on their distribution.LocationSinai, Egypt.MethodsWe built a comprehensive database utilizing all available vegetation plot data of the study area from published literature and our field surveys. We determined the database clustering tendency (Hopkins’ test analysis) and estimated its optimal number of clusters (Elbow method). We performed a cluster analysis (modified TWINSPAN) and improved the validity of the resulting groups by approximating natural clustering using the Silhouette algorithm. We visualized the results by calculating Non‐metric Multidimensional Scaling and drawing distribution maps for the observed vegetation communities.ResultsWe distinguished nine classes representing Sinai desert vegetation: Salicornietea fruticosae, Retametea raetam, Haloxylonetea salicornici, Retamo‐Tamaricetea fluviatilis, Acacietea tortilis, Artemisietea herbae‐albae, Anabasietea articulatae, Chiliadenetea iphionoidis, and Stellarietea mediae. We distinguished 25 vegetation groups, of which seven are new findings, representing four main vegetation groups: salt desert, lowland desert, mountain desert, and ruderal desert. We observed a high diversity in life forms, chorotypes, and alpha‐diversity of the vegetation among the main groups. Therophytes, chamaephytes, hemicryptophytes, and phanerophytes are the dominant life forms. Prevailing chorotypes are Saharo‐Arabian, Mediterranean, Mediterranean‐Irano‐Turanian and Irano‐Turanian‐Saharo‐Arabian. The salt desert and lowland desert vegetation are species‐poor, whereas the mountain desert vegetation is relatively species‐rich. The ruderal desert vegetation is the most species‐rich.ConclusionWe present a common classification of Sinai desert vegetation based on cutting‐edge methods and provide an updated description of the desert vegetation groups of Sinai. Our study forms an important basis for decision‐making in nature conservation, global change issues, and further in‐depth studies on Sinai vegetation.
Characterization of drug–drug interactions on the pharmacokinetic disposition of busulfan in paediatric patients during haematopoietic stem cell transplantation conditioning
Authors: Dunn Allison , Moffett Brady S. , Ivaturi Vijay , Gobburu Jogarao V. S. 
Published: November 2021

AimThe study objective was to develop a population pharmacokinetic model for busulfan to comprehensively examine drug–drug interactions in paediatric patients undergoing haematopoietic stem cell transplantation. Currently, there is limited evidence to substantiate potential drug–drug interactions with busulfan.MethodsThis retrospective study population was comprised of 250 patients receiving, on average, 0.8 mg/kg intravenous busulfan as pretreatment. All model analyses were conducted using nonlinear mixed effects modelling in Pumas v2.0. The metabolic pathways of primary interest were glutathione conjugation and cytochrome P450 (CYP) activity. Concomitant medications were categorized as CYP inhibitors, inducers or glutathione S‐transferase depleters, and included in the model as conditional covariates. A bootstrap simulation and visual predictive check were conducted to qualify the final model.ResultsThe final 1‐compartment model incorporates covariates of weight and age in relation to their effects on both total body clearance and volume of distribution. The estimated typical values of clearance and volume were 1.138 L/h (CI: 1.095–1.179 L/h) and 3.527 L (CI: 3.418–3.621 L), respectively. No significant changes in clearance were observed when medications that alter proposed hepatic and metabolic pathways of busulfan were coadministered.ConclusionTo the best of our knowledge, this is the largest single centre study of busulfan in children and the first to quantify the maturation effect of both clearance and volume. This study could not demonstrate a difference in busulfan clearance when comparing patients who received medications that alter the glutathione S‐transferase, CYP3A4 or CYP2C9 pathway to those who did not.
The impact of B Corp certification on financial stability: Evidence from a multi‐country sample
Authors: Patel Pankaj C. , Dahlin Peter 
Published: November 2021

AbstractB Corps are firms certified by the non‐profit B Lab for pursuing both economic and non‐economic goals. Whether B Corps realize a higher financial performance has met mixed evidence. Drawing on the stability‐change framework, we ask whether B Corp certification is associated with the level and volatility of financial performance. Also, expecting a greater focus on non‐economic activities after certification, equity ratio may decline as shareholders may question the increased non‐economic focus. Using nearest neighbor propensity score matched pair method, we draw on a multi‐country sample of 355 B Corps and 623 non‐B Corps. Our findings are not encouraging. B Corp certification does not provide financial gains nor financial stability, and equity ratio declines and becomes more volatile following certification. Our findings paint a gloomy picture of limited economic benefits and declining participation of equity holders following B Corp certification.
Evaluating the USA population’s interest in sunscreen: a Google Trends analysis
Authors: Maghfour J. , Boothby-Shoemaker W. , Lim H. W. 
Published: November 2021

Abstract
The use of a broad-spectrum sunscreen remains an essential aspect of photoprotection. The environmental and health impacts attributed to certain ultraviolet filters have resulted in public confusion. Hence, the objective of this study is to explore public interest in sunscreen searches using Google Trends.
Rapid response to abatacept in treatment-resistant pansclerotic morphoea
Authors: Attard M. , O’Kane D. 
Published: November 2021

Abstract
Morphoea is a spectrum of disorders characterized by inflammation and sclerosis of the skin and potentially underlying tissues. There are no specific licensed treatments for morphoea and prospective studies on commonly used therapies are lacking. We describe a case of progressive, recalcitrant pansclerotic morphoea with a rapid response to abatacept.
Immediately loaded implants simultaneously placed in fresh extraction and healed sites supporting four‐implant‐supported fixed mandibular prostheses using the all‐on‐4 concept: A 5‐year prospective study
Authors: Krennmair Stefan , Malek Michael , Forstner Thomas , Krennmair Gerald , Stimmelmayr Michael , Hunger Stefan 
Published: November 2021

AbstractObjectivesTo evaluate the peri‐implant marginal bone level for immediately loaded implants placed simultaneously in both fresh extraction sites (FES) and healed sites (HS) supporting a 4‐implant supported mandibular fixed prosthesis (4‐ISFMP) using the all‐on‐4 concept.Material and MethodsA 5‐year prospective study was conducted in 24 patients (96 implants) treated with 4‐ISFMP including 55 implants inserted in FES and 41 implants in HS. At implant placement (baseline) and at the 1st‐, 3rd‐ and 5th‐year follow‐up examinations, peri‐implant marginal bone level was evaluated radiographically and compared between placement in FES and HS. Marginal bone loss was calculated as the difference in the marginal bone level evaluated at the follow‐up periods. Additionally, implant and prosthesis survival rates as well as the presence of peri‐implant mucositis (bleeding on probing+[BOP]) and peri‐implantitis (BOP+ >2 mm MBL) were evaluated.Results22/24 patients with 88/96 implants (dropout rate: 8.3%) were continually followed for 5 years (survival rate: 100%). Radiographically measured marginal bone level differed significantly between FES and HS at implant placement (1.46 ± 0.80 mm vs. 0.60 ± 0.70 mm; p < .001), at the 1‐year (−0.04 ± 0.14 mm vs. −0.18 ± 0.20 mm; p = .002) and 3‐year (−0.26 ± 0.49 mm vs. −0.58 ± 0.48 mm, p = .049), but not at the 5‐year evaluation (−0.90 ± 0.66 mm vs. −1.00 ± 0.59 mm, p = .361). The marginal bone loss differed significantly (p < .001) between FES and HS between implant placement and the 1‐year evaluation but not for the 1‐ to 3‐year (p > .99) and the 3‐ to 5‐year period (p = .082). At the 5‐year follow‐up evaluation, no implant/prosthesis failed (100% survival) and peri‐implant mucositis and peri‐implantitis were noted in 41.2% and 11.7% at patient level and in 17.6% and 4.5% at implant level respectively.ConclusionImplants placed in FES showed a prolonged peri‐implant remodelling process but provided for similar peri‐implant marginal bone levels as implants placed in HS at the 5‐year evaluation for immediately loaded 4‐ISFMP.
A systematic evidence map of conservation knowledge in Chilean Patagonia
Authors: Martínez‐Harms María José , Armesto Juan J. , Castilla Juan Carlos , Astorga Anna , Aylwin José , Buschmann Alejandro H. , Castro Victoria , Daneri Giovanni , Fernández Miriam , Fuentes‐Castillo Taryn , Gelcich Stefan , González Humberto E. , Hucke‐Gaete Rodrigo , Marquet Pablo A. , Morello Flavia , Nahuelhual Laura , Pliscoff Patricio , Reid Brian , Rozzi Ricardo , Guala Cesar , Tecklin David 
Published: November 2021

AbstractMechanisms that reliably and efficiently guide practitioners to find relevant evidence are urgent for conservation decision‐making in Chilean Patagonia. The objective of this study was to systematically collect, characterize, and synthesize the extensive evidence about conservation knowledge in Chilean Patagonia focusing on the impacts of global change drivers on ecosystems and human–nature relationships, identifying knowledge gaps, and providing policy recommendations. The quality of the evidence was assessed through a predefined level‐of‐evidence hierarchy scale, applied to a sample of the studies reviewed. We compiled ~1000 studies documenting that evidence focusing on terrestrial and marine ecosystems has grown exponentially. For terrestrial ecosystems, most studies have addressed climate change, habitat change, and invasive species; while for marine ecosystems, studies have focused on pollution, invasive species, and habitat change. We identified that an important gap is the study of the social dimensions of conservation, and future efforts should focus on incorporating traditional and local knowledge as this can help point the way to ecosystem conservation. The appraisal of the quality of the evidence showed that ~80% of the sample represented reliable evidence with underlying data and an experimental design. Enhanced efforts to deliver this evidence to decision‐makers in a user‐friendly format for evidence uptake in conservation policy are urgent. In this review, we provide a tool that can help practitioners to find evidence reliably to improve decision‐making for the conservation of ecosystems in Chilean Patagonia.
BIOGRAPHICAL NOTES ON MARY YOUNG AND CAROLINE NORTON, ILLUSTRATORS OF MADEIRAN PLANTS FOR CURTIS'S BOTANICAL MAGAZINE IN THE 19th CENTURY
Authors: Mesquita Sandra , Castel‐Branco Cristina , Menezes de Sequeira Miguel 
Published: November 2021

SummaryIn 1834 and 1835, ten plates based on illustrations by ‘Miss Young’ and the ‘Hon. Miss Norton’ were published in Curtis's Botanical Magazine to illustrate texts prepared by Richard Thomas Lowe and sent through his friend William Jackson Hooker. Mary Young is listed in the Dictionary of British and Irish Botanists and Horticulturists Including plant collectors, flower painters and garden designers, for this contribution and the illustrations in Lowe's History of Fishes of Madeira, as ‘companion to Miss Norton’. No other contributions of these illustrators are mentioned, and little is known about them. Here we present more information concerning these two illustrators and their part in Lowe's work on the flora and fish fauna of Madeira.
Obtaining consistent time series from Google Trends
Authors: Eichenauer Vera Z. , Indergand Ronald , Martínez Isabel Z. , Sax Christoph 
Published: November 2021

AbstractGoogle Trends data are a popular data source for research, but raw data are frequency‐inconsistent: daily data fail to capture long‐run trends. This issue has gone unnoticed in the literature. In addition, sampling noise can be substantial. We develop a procedure (available in an R‐package), which solves both issues at once. We apply this procedure to construct long‐run, frequency‐consistent daily economic indices for three German‐speaking countries. The resulting indices are significantly correlated with traditional leading economic indicators while being available in real time. We discuss potential applications across disciplines and spanning well beyond business cycle analysis.
Chinese import competition, offshoring and servitization
Authors: Gu Grace , Malik Samreen , Pozzoli Dario , Rocha Vera 
Published: November 2021

AbstractWe study how domestic firms adapt to increased import competition from China. Using a Danish employer‐employee matched dataset covering firms over the 1995–2007 period, we find that import competition significantly increases manufacturing firms' expansion of their business activities in the service industry (partial servitization); their probability of offshoring production activities abroad and of exiting the market. Import competition, however, does not induce firms to cease all of their involvement in manufacturing production by completely switching into service sector (complete servitization). These findings are confirmed using various robustness tests as well as an analogous analysis of a Portuguese employer‐employee matched dataset.
Current status and role of antiphospholipid antibody testing in cryptogenic stroke
Authors: Yang Wookjin , Kang Min Kyoung , Ha Sue Young , Kang Dong‐Wan , Bae Jeonghoon , Lee Eung‐Joon , Jeong Han‐Yeong , Kim Jeong‐Min , Jung Keun‐Hwa , Lee Seung‐Hoon 
Published: November 2021

AbstractBackground and purposeAlthough it is not recognized as essential to test for antiphospholipid antibody (aPL) in stroke of unknown cause, aPL‐related stroke may account for a considerable number of cryptogenic strokes. We aimed to assess the current status and diagnostic value of aPL testing in cryptogenic stroke patients.MethodsConsecutive patients admitted with acute ischemic stroke were examined to confirm the factors associated with performing aPL testing and with positive aPL test results in real‐world practice. Cryptogenic stroke patients were separately examined in the same manner. The antibody profiles of cryptogenic stroke patients with aPL positivity were compared by age.ResultsAmong 2947 patients, 606 (20.6%) were tested for aPLs and 129 (21.3%) were positive. Physicians tended to perform aPL testing in patients aged <50 years and in cryptogenic stroke patients. Cryptogenic stroke was a strong predictor of positive aPL results (adjusted odds ratio 3.70, 95% confidence interval 2.38–5.76). However, aPL positivity did not differ by age in stroke patients. Among 283 cryptogenic stroke patients, 136 (48.1%) were tested for aPLs and 56 (41.2%) were positive. aPL tests were performed predominantly in patients aged <50 years rather than in older patients, even among cryptogenic stroke patients. The two age groups had similar positivity rates of >40% (<50 years: 43.2%; ≥50 years: 40.4%; p = 0.92) and their antibody profiles were similar.ConclusionsA significant number of patients with cryptogenic stroke had positive aPL results regardless of age. aPL testing may offer additional diagnostic opportunities in cryptogenic stroke patients, and thus may reduce the incidence of cryptogenic stroke.
Coparenting communication and hybrid masculinity in a fatherhood program
Authors: Hammock Amy C. , McKillop Alexander Jack , Hayward R. Anna , Kohli Ekta , Bessaha Melissa L. 
Published: November 2021

AbstractObjectiveThe objective of this study was to examine how involvement in a responsible fatherhood program affected participants' perceptions of masculinity and coparenting communication.BackgroundResponsible fatherhood programs emphasize the importance of being a nurturing and emotionally expressive father, challenging norms of hegemonic masculinity. This study examined how fathers described this hybrid masculinity and its impact on coparenting communication.MethodThematic analysis of 37 semistructured in‐depth interviews with a racially diverse sample of men enrolled in a responsible fatherhood program was conducted. Multiple investigators, researcher reflexivity, and an audit trail enhanced credibility, transferability, and dependability of the findings.ResultsFathers reported three types of communication with the mothers of their child(ren): confrontation, detachment, and engaged perspective‐taking. The latter approaches were learned in the fatherhood program. Fathers described several beliefs and skills affecting these approaches, including the importance of fatherhood, modeling effective communication, controlling one's emotions, and listening and speaking respectfully.ConclusionParticipation in the fatherhood program was useful in deescalating negative interactions and improving communication; however, beliefs about essential gender differences permeated participants' narratives.ImplicationsFuture programming for fathers should include curricula and peer mentoring to challenge norms of traditional masculinity and encourage multiple forms of egalitarian coparenting communication.
A remote sensing‐based three‐source energy balance model to improve global estimations of evapotranspiration in semi‐arid tree‐grass ecosystems
Authors: Burchard‐Levine Vicente , Nieto Héctor , Riaño David , Kustas Wiliam P. , Migliavacca Mirco , El‐Madany Tarek S. , Nelson Jacob A. , Andreu Ana , Carrara Arnaud , Beringer Jason , Baldocchi Dennis , Martín M. Pilar 
Published: November 2021

AbstractIt is well documented that energy balance and other remote sensing‐based evapotranspiration (ET) models face greater uncertainty over water‐limited tree‐grass ecosystems (TGEs), representing nearly 1/6th of the global land surface. Their dual vegetation strata, the grass‐dominated understory and tree‐dominated overstory, make for distinct structural, physiological and phenological characteristics, which challenge models compared to more homogeneous and energy‐limited ecosystems. Along with this, the contribution of grasses and trees to total transpiration (T), along with their different climatic drivers, is still largely unknown nor quantified in TGEs. This study proposes a thermal‐based three‐source energy balance (3SEB) model, accommodating an additional vegetation source within the well‐known two‐source energy balance (TSEB) model. The model was implemented at both tower and continental scales using eddy‐covariance (EC) TGE sites, with variable tree canopy cover and rainfall (P) regimes and Meteosat Second Generation (MSG) images. 3SEB robustly simulated latent heat (LE) and related energy fluxes in all sites (Tower: LE RMSD ~60 W/m2; MSG: LE RMSD ~90 W/m2), improving over both TSEB and seasonally changing TSEB (TSEB‐2S) models. In addition, 3SEB inherently partitions water fluxes between the tree, grass and soil sources. The modelled T correlated well with EC T estimates (r > .76), derived from a machine learning ET partitioning method. The T/ET was found positively related to both P and leaf area index, especially compared to the decomposed grass understory T/ET. However, trees and grasses had contrasting relations with respect to monthly P. These results demonstrate the importance in decomposing total ET into the different vegetation sources, as they have distinct climatic drivers, and hence, different relations to seasonal water availability. These promising results improved ET and energy flux estimations over complex TGEs, which may contribute to enhance global drought monitoring and understanding, and their responses to climate change feedbacks.
Vaccination in children with inherited bleeding disorders: Does the use of plasma an d factor affect the response to the vaccine: An institutional registry
Authors: Tasar Sercin , Tasar Medine Aysin , Alioglu Bulent 
Published: November 2021

AbstractIntroductionWe aimed to evaluate the vaccine seroconversion of paediatric patients with factor deficiency and to complete the missing vaccines. We also emphasize the importance of variables such as recombinant factor and plasma intake frequency.Material and methodsThis prospective observational study includes children between 2 and 17 age diagnosed with inhered factor deficiency. Seroconversion of hepatitis A, hepatitis B, varicella, measles, rubella and mumps vaccines were screened according to Ministry of Health Vaccination Schedule, it was completed if there were seronegative vaccines and the vaccine seroconversion was examined after vaccination approximately 1–6 months.ResultsA total of 61 children were included in the study [mean age 11.2±5.1 years (2–18)], 49 (80.3%) were males. Factor VIII deficiency constituted 60.7%, factor XI 14.8%, factor VII 13.1 %, factor IX 9.8%, factor X 1.6% of the cases. None of the children had clinically important injection site complications such as uncontrollable bleeding or gross hematoma and vaccination does not induce the development of inhibitor. Measles antibody positivity was significantly lower in those who received factor 3 or 4 days times a week compared to those who received it when necessary (p = .049).Discussion and conclusionThis is the first study evaluating the vaccine conversion patients with inherited factor deficiency receiving plasma and plasma derived factor concentrates. It should be considered that children with haemophilia and their families may have vaccination hesitancy; therefore, follow‐up of these patients should include a specified vaccination program to ensure adequate immunization of these patients.