bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhanced local viscosity around colloidal nanoparticles probed by equilibrium molecular dynamics simulations
Authors: Rabani Reza , Saidi Mohammad Hassan , Joly Laurent , Merabia Samy , Rajabpour Ali 
Published: October 2021

Nanofluids—dispersions of nanometer-sized particles in a liquid medium—have been proposed for a wide variety of thermal management applications. It is known that a solid-like nanolayer of liquid of typical thicknesses of 0.5–1 nm surrounding the colloidal nanoparticles can act as a thermal bridge between the nanoparticle and the bulk liquid. Yet, its effect on the nanofluid viscosity has not been elucidated so far. In this article, we compute the local viscosity of the nanolayer using equilibrium molecular dynamics based on the Green–Kubo formula. We first assess the validity of the method to predict the viscosity locally. We apply this methodology to the calculation of the local viscosity in the immediate vicinity of a metallic nanoparticle for a wide range of solid–liquid interaction strength, where a nanolayer of thickness 1 nm is observed as a result of the interaction with the nanoparticle. The viscosity of the nanolayer, which is found to be higher than its corresponding bulk value, is directly dependent on the solid–liquid interaction strength. We discuss the origin of this viscosity enhancement and show that the liquid density increment alone cannot explain the values of the viscosity observed. Rather, we suggest that the solid-like structure of the distribution of the liquid atoms in the vicinity of the nanoparticle contributes to the nanolayer viscosity enhancement. Finally, we observe a failure of the Stokes–Einstein relation between viscosity and diffusion close to the wall, depending on the liquid–solid interaction strength, which we rationalize in terms of the hydrodynamic slip.
Self-powered solar-blind α-Ga2O3 thin-film UV-C photodiode grown by halide vapor-phase epitaxy
Authors: Bae Jinho , Park Ji-Hyeon , Jeon Dae-Woo , Kim Jihyun 
Published: October 2021

A compact self-powered solar-blind UV-C photodiode was demonstrated using an ultra-wide bandgap (UWBG) α-Ga2O3 thin film as a wavelength-selective absorber layer. The UWBG-based Schottky junction architecture renders the use of low-performance and bulky solar-blind UV bandpass filters unnecessary. High-quality α-Ga2O3 thin films with a thickness of 1.25 µm were grown on a (0001) sapphire substrate via the halide vapor-phase epitaxy technique. The self-powered solar-blind UV-C photodetector based on the Ni/α-Ga2O3 Schottky junction exhibited excellent responsivity (1.17 × 10−4 A/W), photo-to-dark current ratio (1.12 × 105), and reproducibility, as well as fast rise/decay characteristics without persistent photoconductivity upon exposure to UV-C radiation (254 nm wavelength). The relationship between light intensity (I) and photocurrent (P) was modeled by I ∼ P0.69, indicating the high-quality of the halide vapor-phase epitaxy-grown α-Ga2O3 thin film. Upon exposure to natural sunlight, the fabricated solar-blind photodetector showed excellent solar blindness with sensitivity to UV-C radiation and did not require an external power source. Therefore, this UWBG α-Ga2O3 thin-film Schottky barrier photodiode is expected to facilitate the development of a compact and energy-independent next-generation UV-C photodetector with solar blindness.
Explicit versus non-explicit prosodic training in the learning of Spanish L2 stress contrasts by French listeners
Authors: Schwab Sandra , Dellwo Volker 
Published: October 2021

Abstract
Different methods to acquire a language can contribute differently to learning success. In the present study we tested the success of L2 stress contrasts acquisition, when ab initio learners were taught or not about the theoretic nature of L2 stress contrasts. In two 4-hour perceptual training methods, French-speaking listeners received either (a) explicit instructions about Spanish stress patterns and perception activities commonly used in L2 pronunciation courses or (b) no explicit instructions and a unique perception activity, a shape/word matching task. Results showed that French-speaking listeners improved their ability to identify and discriminate stress contrasts in Spanish after training. However, there was no significant difference between explicit and non-explicit training nor was there an effect on stress processing under different phonetic variability conditions. This suggests that in L2 stress acquisition, non-explicit training may benefit ab initio learners as much as explicit instruction and activities used in L2 pronunciation courses.
Learner translation of metaphor
Authors: Nacey Susan , Skogmo Siri Fürst 
Published: October 2021

Abstract
This article explores metaphor translation strategies of novice translators: university students translating from L1 Norwegian to L2 English. We first describe the translation strategies they employ in their translated texts, thereby offering evidence of what translators do with metaphor based on multiple translations of the same metaphor-dense source text. We then go beyond this descriptive analysis to discuss why these translators make their particular choices, analyzing the students’ in-class discussion and individual written reflections about their translations. We thus illuminate the challenges that the novice translators consciously perceive (that is, is metaphor a problem?), as well as their motivation for and evaluation of their translation solutions. In this way, we shed light on the concept of the ‘successful’ translation of metaphor.
The relationship between topic and metaphor in second-language learners’ essays
Authors: Golden Anne 
Published: October 2021

AbstractIn this article I investigate to what extent the use of metaphorical expressions in language learners’ texts vary according to the topic they have chosen to write about. The data come from the Norwegian learner corpus ASK, where the texts are from written assignments produced by adult second-language learners as part of an official Norwegian test and texts. Texts from two different prompts are selected, which are related to friendship and nature. Metaphors are defined according to conceptual metaphor theory and a triangulation of methods is used, alternating between a manual and an automatic extraction method.The results confirm the hypothesis that the two different prompts given to the learners in a language test not only triggers different metaphorical expressions but also influences the amount of metaphor used in the learners’ writing. This knowledge is important to researchers for comparing the use of metaphors between different groups, such as between different learners or between students in different stages of education. It is also important for test designers who decide on topics to be used in tests and teachers who help learners prepare for their tests. In addition, it is of interest for researchers, educators in general and the learners themselves who are interested in the effect the use of metaphors in texts have on raters’ evaluations in high-stake tests.
Answering the charge?
Authors: Askeland Norunn 
Published: October 2021

AbstractFrom 1850 to 1980 the Norwegian state pursued a policy of Norwegianization of the Sami, where schools played an important part in the attempt to turn Sami children into Norwegian citizens. Pupils lived in boarding schools where all teaching was in Norwegian and it was forbidden to speak Sami, both in and out of the classroom. This article examines metaphors in three types of material: Norwegian textbooks; Sami literature in these textbooks; and Sami testimony literature. The aim is to find out how the Norwegian state used its power to stigmatize Sami identity through metaphors in textbooks, and how Sami writers show their resistance to Norwegianization through metaphors in Sami literary texts and Sami testimony literature. The analysis also examines whether metaphors are signalled or not, in order to see if they are open to negotiation or taken as self-evident, and if signalling can be related to genre. One central finding is that the Norwegian texts contain more condescending and less signalled metaphors than the Sami ones. Another is that signalling might be related to genre: there are more signalled metaphors in the reflective narratives of witness testimonies than in the other genres that are examined. The theoretical foundations of the analyses are discourse-based metaphor analysis in a post-colonial perspective.
785 Is Subspecialisation Important for The Emergency Laparotomy Outcomes?
Authors: Chowdhury S , Musbahi A , Agarwal A 
Published: October 2021

Abstract

Introduction
High mortality and morbidity is associated with Emergency Laparotomy. This study looks at outcomes of different subspecialties of surgeons performing Emergency Laparotomies identified from National Emergency Laparotomy Audit (NELA).

Method

Results

Conclusions
1026 Assessing the Reliability of 3D Imaging for Wound Measurements
Authors: Hitchman L , Cai P , Sethi S , Stirrup A , Lathan R , Sidapra M , Smith G , Carradice D , Chetter I 
Published: October 2021

Abstract

Aim
To investigate the inter and intra reliability of using 3D imaging to measure wounds.

Method
20 wound models of 4 different shaped wounds in 5 different colours were created from plastic mouldable beads. 3D images were taken using the BlasterX Senz3D camera and measured using the GPC Wound Measure application (version 3.15.0.0, UK). Intra-user reliability was determined comparing 20 wound measurements of each wound model. Inter-user reliability was determined by 5 different clinicians photographing each model and independently measuring each wound photo. The inter- and intra-rater measurements for wound surface area and volume were compared using the ICC and differences from the overall mean plotted on Bland-Altman graphs.

Results
The interclass co-efficient (ICC) for inter-rater reliability in measuring surface area was 0.958 (95% CI 0.919-0.981, p &lt; 0.005). The intra-rater reliability when measuring wound surface area was 0.996 (95% CI 0.993-0.998, p &lt; 0.005). For wound volume, the ICC for inter-rater reliability was 0.925 (95% CI 0.857-0.967, p &lt; 0.005) and 0.999 (95% CI 0.998-0.999, p &lt; 0.005) for intra-user reliability. 5.5% of measurements were outside 2 SD of the mean for wound volume.

Conclusions
3D imaging offers a quick, reliable, and easy to use solution to measuring wounds. We have shown it is a reliable and reproducible method of measuring wounds between different clinicians.
1039 Assessing the Efficacy of The Modified S-PECS Anaesthetic Block in Patients Undergoing Breast Augmentation Surgery – A Randomised Double-Blind Control Trial
Authors: Saghir R , Saghir N , Okhiria R , Okhiria T , Sidhu M , Husein R , Sforza M 
Published: October 2021

Abstract

Aim
Postoperative acute on chronic pain following breast surgery is a common complication which needs resolving to allow for improved patient outcomes. Previously thoracic epidurals and paravertebral blocks (PVB) have been the gold standard administered intra-operatively. However, more recently the introduction of the Pectoral nerve block (PECS and PECS-2 blocks) has looked promising to control the pain more effectively, but further robust analysis is required to prove its efficacy. The authors aim to study the efficacy of a new block S-PECS that comprises a serratus anterior and a PECS-2 block associated.

Method
In this study we performed a prospective, single-centre randomised controlled double-blind group trial in 30 female patients undergoing breast augmentation surgery with silicone breast implants and the S-PECS block. Divided into groups of 15, the S-PECS group received local anaesthetics with the no-PECS control group receiving a saline injection. All participants were followed up at recovery (REC), 4, 6 and 12 (4H, 6H and 12H) hourly postoperatively.

Results
Our results showed that the pain score in the S-PECS group was significantly less than the no-PECS group across all time points REC, 4H, 6H and 12H. Furthermore, the patients that received the S-PECS block were 74% less likely to request pain medications compared to the no-PECS group (p &lt; 0.05).

Conclusions
Overall, the modified S-PECS block is an effective, efficient, and safe method of controlling pain in patients undergoing breast augmentation surgery with additional applications yet to be explored.
1609 Patient Demographics and Outcomes Following Acute Presentation with An Inguinal Hernia; A 15-Year Retrospective Cohort Study from The North of England
Authors: Clyde D , Li L , Swan R , McLean R , Brown L 
Published: October 2021

Abstract

Aim
Although inguinal hernia repair is one of the most common elective procedures performed, emergency repair carries a far greater risk to patients. This study aimed to report on patient demographics and outcomes following emergency presentation with an inguinal hernia.

Method
Patients ≥18 years admitted acutely with an inguinal hernia across NHS trusts in the North of England between 2002-2016 were identified. Data were collected on demographics, investigations, and operative interventions. Outcomes including length of stay (LoS) and 30-day mortality were analysed.

Results
A total of 4698 patients presented over the 15-year study period. The cohort were predominantly male (n = 4133, 88.0%) with median age of 71 years (IQR: 56-81). Whilst no significant difference in age or gender were found across the study period, comorbidities, as measured by Charlson score, increased over time (p &lt; 0.001). In those who underwent operative intervention (n = 2580), median length of stay was 3 days (IQR: 2-5) and 30-day inpatient mortality rate was 2.5%. Advanced age and comorbidity were associated with higher overall 30-day mortality and post-operative 30-day mortality (both p &lt; 0.001).

Conclusions
This study highlights the frailty of patients presenting as emergency with complications secondary to inguinal hernia. Given the increased risk observed in this patient group, it is vital that perioperative care is optimised, and patients are counselled appropriately.
1095 The Utility of Plasma Circulating Cell-Free Messenger RNA as A Biomarker of Glioma: A Pilot Study
Authors: Ita M , Wang J H , Toulouse A , Lim C , Fanning N , O’Sullivan M , Nolan Y , Kaar G , Redmond H 
Published: October 2021

Abstract

Introduction
Research into the potential utility of plasma-derived circulating-cell-free nucleic acids as non-invasive adjuncts to radiological imaging has been occasioned by the invasive nature of brain tumour biopsy. Circulating-cell-free messenger RNAs are short fragments of RNA present in blood. The objective of this study was to determine whether significant differences exist in the plasma transcriptomic profile of glioma patients relative to differences in their tumour characteristics, and also whether any observed differences were representative of synchronously obtained glioma samples and TCGA glioma derived RNA.

Method
Blood samples were collected from twenty-nine patients prior to tumour resection. Plasma-ccfmRNA and glioma derived RNA were extracted and profiled.

Results
BCL2L1, CXCL5, GZMB, HLA-A, HLA-C, IRF1, MYD88, TGFB1, TLR2, and TP53 genes were significantly over-expressed in glioma (high-grade-glioma-HGG and low-grade-glioma-LGG) patients (p &lt; 0.05, versus control). BCL2L1, GZMB and HLA-A genes were significantly over-expressed in HGG patients (p &lt; 0.05, versus LGG patients). There was positive correlation between the magnitude of fold change of differentially expressed genes in plasma and glioma derived RNA (Spearman r = 0.6344, n = 14, p = 0.017), and with the mean FPKM of TCGA glioma derived RNA samples (Spearman r = 0.4614, n = 19, p = 0.047). There was positive correlation between glioma radiographic tumour burden and the magnitude of fold change of CSF3 gene (r = 0.9813, n = 20, p &lt; 0.001).

Conclusions
We identified significant differential expression of genes involved in cancer inflammation and immunity among patients with different glioma grades, and we identified positive correlation between the plasma transcriptomic profile and tumour samples, and with TCGA glioma derived RNA.
1692 No Longer Unknown: A Systematic Review & Meta-Analysis of The Effectiveness of Trans-Oral Surgical Techniques in Identifying Head and Neck Primary Cancer in Carcinoma Unknown Primary
Authors: Gao C , Al-Lami A , Al-Zuhir N , Simo R , Arora A , Jeannon J P 
Published: October 2021

Abstract

Aim
The use of transoral robotic surgery (TORS), transoral laser microsurgery (TLM) and more recently reported transoral endoscopic electrocautery (TOEC) in the identification of the primary cancer in CUP patients has gained popularity. This systematic review aims to assess the effectiveness of TORS, TLM and TOEC.

Method
A systematic review and meta-analysis using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) reporting methodology was carried out to assess the effectiveness of the three trans-oral surgical techniques. EMBASE, MEDLINE and CINAHL databases were searched from inception to September 2020. Primary outcome measure was detection rates of primary cancer of the different techniques. Secondary outcome measures were complications and length of hospital stay.

Results
289 studies were identified of which 30 met the inclusion criteria (28 case series and 2 case reports). The overall combined primary identification rate was 72.3% (567 /777 patients). The primary identification rates were 49.7% and 34.2% in lingual (n = 273) and palatine tonsillectomy (n = 118) respectively. The primary cancer identification rates by surgical techniques are: TORS was 60% (CI 0.49, 0.70), TLM was 80% (CI 0.58, 1.01), TOEC was 41% (CI 0.05, 0.76). The commonest complication was haemorrhage (5.3%).

Conclusions
This is the largest systematic review in the subject and incorporates the more recently published surgical technique of TOEC. Lingual tonsillectomy is an effective procedure in CUP work up. Further larger, multi-centre, prospective studies of PET CT negative CUP patients is needed to draw conclusive results
715 The Importance of Social Media to The Academic Surgical Literature: Relationship Between Twitter Activity and Readership Metrics
Authors: Mobarak S , Stott M , Lee W J , Davé M , Tarazi M , Macutkiewicz C 
Published: October 2021

Abstract

Aim
Social media (SoMe) has an increasing role within professional surgical practice, including the publishing and engagement of academic literature. This study aims to analyse the relationship between social media use and traditional and alternative metrics amongst academic surgical journals.

Method
Journals were identified through the InCites Journal Citation Reports 2019, and their impact factor (IF), h-index and CiteScore were noted. Social media platforms were examined, and Twitter activity interrogated between 1st January- 31st December 2019. Healthcare Social Graph (HSG) score and an aggregated Altmetric score were also calculated for each journal. Statistical analysis was carried out to look at the correlation between traditional metrics, Twitter activity and altmetrics.

Results
Journals with higher IF were more likely to use a greater number of SoMe platforms (R2=0.648; p &lt; 0.0001). Journals with dedicated Twitter profiles had a higher IF than journals without (median, 2.96 vs 1.88; MWU=390; p &lt; 0.001) however over a one-year period (2018-2019) having a twitter presence did not alter IF (MWU=744.5; p = 0.885). Increased Twitter activity was positively correlated with IF. Longitudinal analysis over six years suggested cumulative tweets correlated with an increased IF (R2=0.324, p = 0.004). Novel alternative measures including HSG score (R2=0.472, p = 0.005) and Altmetric score (R2=0.779, p = 0.001) positively correlated with IF.

Conclusions
Higher IF is associated with SoMe presence and activity, particularly on Twitter, with long term activity being of particular importance. Modern alternative metrics correlate with IF. This relationship is complex and future studies should look to understand this further.
984 Changing the Management of Epistaxis in the Covid-19 Era
Authors: Kerr B , Dalton J , Stewart R , Stewart R , McGahey D 
Published: October 2021

Abstract

Aim
Epistaxis in the Covid pandemic is a concerning problem facing otolaryngologists due to high droplet concentration and increased virulence in nasal secretions. Furthermore, safe ambulation of patients reduces Covid exposure and preserves essential resources. This study assessed the implementation of ENT UK recommended altered epistaxis management during the Covid pandemic.

Method
Patients presenting to a medium-sized community hospital with unrelenting epistaxis had a rapid rhino (RR) inserted. Able patients were ambulated and given an appointment for RR removal. Previously all patients were admitted. A comparative retrospective analysis of patients referred with epistaxis was conducted using electronic care records from March – August 2019 versus the same period in 2020. Follow-up phone-call was also employed. Admissions, bed days, RR complications and patient satisfaction was assessed. Data was analysed student t-tests.

Results
A significant reduction in admissions (n = 91; P &lt; 0.001) and bed days (n = 104; P &lt; 0.001) was observed. Only 2 out of the 68 patients ambulated required medical assistance prior to their scheduled appointment (3%; P &lt; 0.001). The majority of patients were satisfied (91%) and reported no bleeding (94%). No RR dislodgement occurred (0%) and most patients were pleased to avoid admission (92%). 70% of patients reported severe pain following RR insertion.

Conclusions
Ambulation of patients presenting to ED with unrelenting epistaxis managed with RR insertion is a safe alternative to previous practice with few complications. Furthermore, patients are largely satisfied although reported severe pain post RR insertion needs addressed. Finally, this altered management reduces contact and preserves resources as our hospitals face overwhelming pressures.
437 Impact of COVID-19 on West of Scotland Colorectal Cancer Services
Authors: Welsh S , Al-Ani A 
Published: October 2021

Abstract

Aim
The coronavirus disease 19 (COVID-19) pandemic has driven unprecedented restriction of the National Health Service to accommodate additional pressures. Our aim was to analyse the impact of COVID-19 on the largest colorectal cancer (CRC) services in NHS Greater Glasgow & Clyde.

Method
Audit data collected from multidisciplinary team meetings for South Glasgow CRC service were accessed. We compared April-June 2020 (‘Lockdown group’) to corresponding months in 2019 (‘Control group’). Statistical analysis by unpaired T-test, Pearson’s χ2 test with post hoc analysis using adjusted Z scores and Bonferroni correction as appropriate.

Results
There was a 39.5% reduction in CRC diagnoses during lockdown (n = 49) compared to control (n = 81). There was a 34.1% reduction in CRC operations during lockdown (n = 27) compared to control (n = 52). The proportion of patients managed operatively did not differ between groups (p = 0.140). There was no difference in the number of days from diagnosis to first treatment between Lockdown and Control groups (Mean(SD): 40.1±35.3 and 43.2±42.9, p = 0.257). Primary care physicians were the main referral source for both lockdown (52%) and control groups (46%). The cessation of bowel screening programme saw no referrals in lockdown whereas it accounted for 21% of referrals in control group, p &lt; 0.001).

Conclusions
We experienced dramatic reductions in CRC diagnoses during lockdown that was not only accounted for by the cessation of bowel screening. The diagnostic delay in the 39.5% ‘missed’ CRC patients may result in patient morbidity; a severe repercussion of COVID-19. The resurgence of COVID-19 cases poses a real threat to cancer services.