bluuebunny/crossref_metadata_2025_split huggingface dataset:
25179 The Community Mentor for Scholars Program: Pilot Program Results
Authors: Merrifield Angela , Lamere Michelle , Riggs Sheila , Bowman Nicole , Fulkerson Jayne A. , Shanedling Janet , Rohde Sara , Ingbar David H 
Published: March 2021

ABSTRACT IMPACT: Strengthening investigator and community engagement to improve human health OBJECTIVES/GOALS: Community Engagement is one of the 14 core competencies for CT research defined by the CTSA Education Core Competency Work Group. To meet this, the UMN CTSI created the Community Mentor for Scholars Program with goals to: 1) train Scholars to engage stakeholders; and 2) provide community with formal mentoring training and linkages to researchers at UMN. METHODS/STUDY POPULATION: The CM Program was implemented over 12 months and includes four components. One, Scholars were trained in stakeholder identification and working with a community mentor (CM) through two seminars presented by expert faculty and staff. Two, CMs were identified, recruited, and matched with Scholars through a collaborative effort of our CTSI Education and Community Engagement cores. Three, Scholars and CMs learned about the program from a 2-hour Kick-Off event. Four, CMs and Scholars each completed four online modules developed through an NCATS administrative supplement. Scholar-CM pairs met at least four times to plan and hold a bi-directional ‘Community Conversation’ with an audience of key stakeholders convened by the CM. The CM Program was evaluated through in-person interviews. RESULTS/ANTICIPATED RESULTS: In 2019-2020, CTSI initiated the pilot program with four KL2 Scholar - CM pairs. Two pairs did not complete the program due to time pressures, a parental leave, and the COVID-19 pandemic. Feedback from the two Scholar - CM pairs was positive, specifically:CMs reported the training modules were useful, resulting in better understanding of CTSI research programs and increased capacity to mentorScholars felt the interactions with CMs positively impacted their future researchMentors supported experiential learning, offered insight on community perspectives, and successfully facilitated community engagement principles. DISCUSSION/SIGNIFICANCE OF FINDINGS: The second cohort launched in late 2020 with inclusion of TL1 Scholars. They will be matched with CMs in spring 2021. After Cohort 2 completion, the program design and materials will be updated based on evaluation results from scholars and mentors and then will be piloted with select CTSAs before sharing across the CTSA consortium.
Planting native trees to restore riparian forests increases biotic resistance to nonnative plant invasions
Authors: Hammer Chad F. , Gunn John S. 
Published: March 2021

AbstractNonnative invasive plant species are a major cause of ecosystem degradation and impairment of ecosystem service benefits in the United States. Forested riparian areas provide many ecosystem service benefits and are vital to maintaining water quality of streams and rivers. These systems are also vulnerable to natural disturbances and invasion by nonnative plants. We assessed whether planting native trees on disturbed riparian sites may increase biotic resistance to invasive plant establishment in central Vermont in the northeastern United States. The density (stems per square meter) of invasive stems was higher in non-planted sites (x̄ = 4.1 stems m−2) compared with planted sites (x̄ = 1.3 stems m−2). More than 90% of the invasive plants were Japanese knotweed [Fallopia japonica (Houtt.) Ronse Decr.; syn. Polygonum cuspidatum Siebold & Zucc.]. There were no significant differences in total stem density of native vegetation between planted and non-planted sites. Other measured response variables such as native tree regeneration, species diversity, soil properties, and soil function showed no significant differences or trends in the paired riparian study sites. The results of this case study indicate that tree planting in disturbed riparian forest areas may assist conservation efforts by minimizing the risk of invasive plant colonization.
‘I have been obliged to Send Nassaw’: an enslaved healer’s medical labour and skill in eighteenth-century Virginia
Authors: Blakley Christopher M. 
Published: March 2021

AbstractThis article examines the medical career of an enslaved physician in Virginia named Nassaw from the mid eighteenth-century until the period of the American Revolution. I develop a taxonomy of Nassaw’s labours as a nurse caring for the sick, a healer administering medicines at the behest of his enslaver and as a doctor in his own right making medical judgements as he treated his patients. Nassaw is in some ways comparable to other enslaved healers of African descent in the Atlantic world, including well-known Mohanes and ritual specialists in Brazil and Latin America. However, due to his role as a physician employed by his slaveholder to principally heal other enslaved people, Nassaw struggled to find satisfaction in his labours as a healer as other enslaved people rightly perceived him as an agent of their enslaver whose medical work healed their bodies while extending their oppression. I argue that Nassaw became frustrated and depressed, and turned to drinking because of his inability to pursue or experience what Sharla M. Fett terms a ‘relational vision of health’ in the Chesapeake. Moreover, I interpret his drinking as a rebuke to the racist pretensions of his enslaver – who instructed him in pharmacy and surgery – who aimed to transform Nassaw into an Enlightened ‘black exhibit’ by training him to be a doctor. I conclude by returning to how precisely different Nassaw was from other enslaved healers in the Chesapeake like Tom of Nomini Hall or Romeo, and make the case that Nassaw deserves a place in histories of slavery and medicine precisely because he was an enslaved plantation doctor rather than a popular healer or conjuror.
Attending the birth: competition for obstetrical training by medical students and midwives in nineteenth-century France
Authors: Martin Morag 
Published: March 2021

AbstractThough male doctors gained prominence at the bedsides of pregnant mothers in nineteenth-century Europe, the clinical training they received in medical academies remained cursory. In France, to supplement the medical faculties, the government set up schools for both health officers and midwives which were meant to teach practical obstetrics. This paper focusses on the city of Arras, where these two groups of students competed for the limited numbers of pregnant patients on which to practice their future professions. Like many in their field, two prominent instructors in Arras at each end of the century promoted male obstetrical education over female, arguing that practical education for health officers would lead to safer births for mothers and infants. By the 1870s, the obstetrics instructor adopted germ theory, tying improved hygiene and thus mortality rates to male students’ access to hospitalised patients. Despite their arguments, in Arras, the male students never gained priority in clinical obstetrical training, which midwifery students kept. To keep male students out of maternity wards, local administrators used fears that gender mixing would lead to immoral acts or thoughts. In doing so, they protected the traditional system of midwifery rather than invest in more costly male medical education. Championing midwifery students’ rights to the spaces and bodies needed for their education, however, delayed adoption of hygiene and antiseptic practices that led to lower maternal mortality. Unable to adapt to changing requirements by the state, the medical school closed in 1883, while the midwifery programme thrived until the 1960s.
Voluntary use of automated writing evaluation by content course students
Authors: Saricaoglu Aysel , Bilki Zeynep 
Published: March 2021

AbstractAutomated writing evaluation (AWE) technologies are common supplementary tools for helping students improve their language accuracy using automated feedback. In most existing studies, AWE has been implemented as a class activity or an assignment requirement in English or academic writing classes. The potential of AWE as a voluntary language learning tool is unknown. This study reports on the voluntary use of Criterion by English as a foreign language students in two content courses for two assignments. We investigated (a) to what extent students used Criterion and (b) to what extent their revisions based on automated feedback increased the accuracy of their writing from the first submitted draft to the last in both assignments. We analyzed students’ performance summary reports from Criterion using descriptive statistics and non-parametric statistical tests. The findings showed that not all students used Criterion or resubmitted a revised draft. However, the findings also showed that engagement with automated feedback significantly reduced users’ errors from the first draft to the last in 11 error categories in total for the two assignments.
What makes a good-quality language MOOC? An empirical study of criteria to evaluate the quality of online language courses from learners’ perspectives
Authors: Luo Rong , Ye Zixuan 
Published: March 2021

AbstractThis paper focuses on quality assurance in language massive open online courses (LMOOCs). It is a qualitative study that adopts the grounded theory method and analyses evaluative comments on the quality of LMOOCs from learners’ perspectives. With the data collected from 1,000 evaluations from English as a second language (ESL) learners on China’s biggest MOOC platform “iCourse”, this study examines what has influenced learners’ perceptions of LMOOCs and identifies the specific quality criteria of five types of them, including ESL courses for speaking, reading, writing, cultural studies, and integrated skills. The results of the study will lay a foundation for the establishment of a quality criteria framework for LMOOCs and provide insights into design principles for effective online language courses tailored to the diverse needs of a massive number of language learners.
Perceived Fatigue Impact and Cognitive Variability in Multiple Sclerosis
Authors: Riegler Kaitlin E. , Cadden Margaret , Guty Erin T. , Bruce Jared M. , Arnett Peter A. 
Published: March 2021

AbstractObjective:People with Multiple Sclerosis (PwMS) and healthy controls (HCs) were evaluated on cognitive variability indices and we examined the relationship between fatigue and cognitive variability between these groups. Intraindividual variability (IIV) on a neuropsychological test battery was hypothesized to mediate the group differences expected in fatigue.Method:Fifty-nine PwMS and 51 HCs completed a psychosocial interview and battery of neuropsychological tests and questionnaires during a 1-day visit. Fatigue in this study was measured with the Fatigue Impact Scale (FIS), a self-report multidimensional measure of fatigue. IIV was operationalized using two different measures, a maximum discrepancy score (MDS) and intraindividual standard deviation (ISD), in two cognitive domains, memory and attention/processing speed. Two mediation analyses with group (PwMS or HCs) as the independent variable, variability composite (memory or attention/processing speed) measures as the mediators, total residual fatigue (after accounting for age) as the outcome, and depression as a covariate were conducted. The Baron and Kenny approach to testing mediation and the PROCESS macro for testing the strength of the indirect effect were used.Results:Results of a mediation analysis using 5000 bootstrap samples indicated that IIV in domains of both attention/processing speed and memory significantly mediated the effect of patient status on total residual fatigue.Conclusion:IIV is an objective performance measure that is related to differences in fatigue impact between PwMS and HCs. PwMS experience more variability across tests of attention/processing speed and memory and this experience of variable performance may increase the impact of fatigue.
Controls on Organic Carbon Burial in the Eastern China Marginal Seas: A Regional Synthesis
Authors: Zhao B. , Yao P. , Bianchi T. S. , Yu Z. G. 
Published: March 2021

AbstractA regional synthesis of organic carbon (OC) burial was conducted using a comprehensive data set to reveal some of the key drivers and human multi‐stressors controlling OC burial and transport in the Eastern China Marginal Seas (ECMS). Both OC and Δ14C values of suspended particulate matter (SPM) in the Changjiang River, were significantly higher than estuarine mobile‐muds, suggesting selective decay of more labile younger OC from both marine and terrestrial sources and the accumulation of more recalcitrant older OC. Some of this decay is likely to be associated with iron‐redox cycling in mobile‐muds. In contrast, OC, δ13C, and Δ14C values increased along the Yellow River sediment dispersal pathway, indicating adding of young marine OC and less decay of terrestrial OC. OC burial efficiency in mud areas in the Bohai Sea (∼43%) was significantly higher than those in the Yellow (∼11%) and East China Seas (∼16%), owing to rapid deposition. Burial flux of biospheric OC in mud areas of the ECMS is 7.00 ± 0.79 Mt yr−1, corresponding to atmospheric CO2 drawdown by silicate weathering in major river drainage basins of mainland China. The burial flux of petrogenic OC was estimated to be 0.81 ± 0.25 Mt yr−1, accounting for >1.9% of total burial in the global ocean. While the ECMS is an important OC sink, river damming has greatly reduced OC burial. Thus, the overall impact on anthropogenically altered river‐dominated marginal seas remains an important and rapidly changing component of the coastal ocean carbon budget.
Marine Electromagnetic Imaging and Volumetric Estimation of Freshwater Plumes Offshore Hawai'i
Authors: Attias Eric , Constable Steven , Sherman Dallas , Ismail Khaira , Shuler Christopher , Dulai Henrietta 
Published: March 2021

AbstractSubmarine groundwater discharge (SGD) is an important phenomenon that governs hydrological cycles at the land‐to‐ocean transition zone. SGD manifests as cold and buoyant freshwaters influx from the seafloor to the water column that contains carbon, nutrients, metals, and greenhouse gases, altering coastal areas' oceanographical and biochemical properties. Here, we present electromagnetic imaging of large‐scale freshwater plumes in high‐resolution, offshore west Hawai'i. Electrical resistivity models detect multiple vertical freshwater plumes extending from the seafloor to the ocean surface. Additionally, our models image extensive spatially distributed surface freshwater. The resistivity of these plumes and surface freshwater ranges from ∼1 to 30 Ωm. Resistivity‐to‐salinity calculation indicates a plume‐scale salinity range of ∼0.3–9.9, containing up to 87% of freshwater. Our results imply that substantial volumes of freshwater occupy water column plumes in Hawai'i. This study offers a new and effective method to elucidate hydrogeologic and ocean processes affecting biogeochemical cycles in coastal waters worldwide.
Enhanced Carbonate Dissolution Associated With Deglacial Dysoxic Events in the Subpolar North Pacific
Authors: Payne Calie R. , Belanger Christina L. 
Published: March 2021

AbstractHere we use volume density (ρV) measurements as a metric of size‐normalized weights for Neogloboquadrina pachyderma, a planktonic foraminifer, from upper OMZ and abyssal depth sites in the Gulf of Alaska over the past ∼20,000 years to test for covariation between carbonate preservation and OMZ intensity. We find that dissolution of N. pachyderma is most intense at the upper OMZ site where oxygenation is generally lower than at the abyssal site. We also examine Uvigerina peregrina, a benthic foraminifer, at the upper OMZ site and find that the lowest ρV measurements in both taxa occur during deglacial and early Holocene dysoxic events. We use computed tomography images to confirm that changes in ρV are related to shell thickness, observe dissolution features, and test for growth influences on ρV. Further, we use stepwise selection of multiple regression models in which coregistered environmental proxies are potential predictors of ρV and find that the best supported models retain negative associations between ρV and the concentration of redox‐sensitive metals and the relative abundance of dysoxia‐tolerant and opportunistic benthic foraminifera, indicating that low ρV is associated with low‐oxygen conditions and pulsed availability of organic matter at the seafloor. Taken together, our results suggest the primary driver of carbonate dissolution here is related to organic carbon respiration at the seafloor. This highlights the importance of metabolic dissolution in understanding the inorganic carbon cycle and the role regions with high‐organic carbon export, such as OMZs, can have as CO2 sources as metabolic dissolution intensifies.
Sulfoquinovose is a select nutrient of prominent bacteria and a source of hydrogen sulfide in the human gut
Authors: Hanson Buck T , Dimitri Kits K , Löffler Jessica , Burrichter Anna G , Fiedler Alexander , Denger Karin , Frommeyer Benjamin , Herbold Craig W , Rattei Thomas , Karcher Nicolai , Segata Nicola , Schleheck David , Loy Alexander 
Published: March 2021

Abstract
Responses of the microbiota to diet are highly personalized but mechanistically not well understood because many metabolic capabilities and interactions of human gut microorganisms are unknown. Here we show that sulfoquinovose (SQ), a sulfonated monosaccharide omnipresent in green vegetables, is a selective yet relevant substrate for few but ubiquitous bacteria in the human gut. In human feces and in defined co-culture, Eubacterium rectale and Bilophila wadsworthia used recently identified pathways to cooperatively catabolize SQ with 2,3-dihydroxypropane-1-sulfonate as a transient intermediate to hydrogen sulfide (H2S), a key intestinal metabolite with disparate effects on host health. SQ-degradation capability is encoded in almost half of E. rectale genomes but otherwise sparsely distributed among microbial species in the human intestine. However, re-analysis of fecal metatranscriptome datasets of four human cohorts showed that SQ degradation (mostly from E. rectale and Faecalibacterium prausnitzii) and H2S production (mostly from B. wadsworthia) pathways were expressed abundantly across various health states, demonstrating that these microbial functions are core attributes of the human gut. The discovery of green-diet-derived SQ as an exclusive microbial nutrient and an additional source of H2S in the human gut highlights the role of individual dietary compounds and organosulfur metabolism on microbial activity and has implications for precision editing of the gut microbiota by dietary and prebiotic interventions.
Sulfate formation is dominated by manganese-catalyzed oxidation of SO2 on aerosol surfaces during haze events
Authors: Wang Weigang , Liu Mingyuan , Wang Tiantian , Song Yu , Zhou Li , Cao Junji , Hu Jingnan , Tang Guigang , Chen Zhe , Li Zhijie , Xu Zhenying , Peng Chao , Lian Chaofan , Chen Yan , Pan Yuepeng , Zhang Yunhong , Sun Yele , Li Weijun , Zhu Tong , Tian Hezhong , Ge Maofa 
Published: March 2021

AbstractThe formation mechanism of aerosol sulfate during wintertime haze events in China is still largely unknown. As companions, SO2 and transition metals are mainly emitted from coal combustion. Here, we argue that the transition metal-catalyzed oxidation of SO2 on aerosol surfaces could be the dominant sulfate formation pathway and investigate this hypothesis by integrating chamber experiments, numerical simulations and in-field observations. Our analysis shows that the contribution of the manganese-catalyzed oxidation of SO2 on aerosol surfaces is approximately one to two orders of magnitude larger than previously known routes, and contributes 69.2% ± 5.0% of the particulate sulfur production during haze events. This formation pathway could explain the missing source of sulfate and improve the understanding of atmospheric chemistry and climate change.
Real-space observation of ferroelectrically induced magnetic spin crystal in SrRuO3
Authors: Seddon S. D. , Dogaru D. E. , Holt S. J. R. , Rusu D. , Peters J. J. P. , Sanchez A. M. , Alexe M. 
Published: March 2021

AbstractUnusual features in the Hall Resistivity of thin film systems are frequently associated with whirling spin textures such as Skyrmions. A host of recent investigations of Hall Hysteresis loops in SrRuO3 heterostructures have provided conflicting evidence for different causes for such features. We have constructed an SrRuO3-PbTiO3 (Ferromagnetic – Ferroelectric) bilayer that exhibits features in the Hall Hysteresis previously attributed to a Topological Hall Effect, and Skyrmions. Here we show field dependent Magnetic Force Microscopy measurements throughout the key fields where the ‘THE’ presents, revealing the emergence to two periodic, chiral spin textures. The zero-field cycloidal phase, which then transforms into a ‘double-q’ incommensurate spin crystal appears over the appearance of the ‘Topological-like’ Hall effect region, and develop into a ferromagnetic switching regime as the sample reaches saturation, and the ‘Topological-like’ response diminishes. Scanning Tunnelling Electron Microscopy and Density Functional Theory is used to observe and analyse surface inversion symmetry breaking and confirm the role of an interfacial Dzyaloshinskii–Moriya interaction at the heart of the system.
Multicentric tracking of multiple agents by anterior cingulate cortex during pursuit and evasion
Authors: Yoo Seng Bum Michael , Tu Jiaxin Cindy , Hayden Benjamin Yost 
Published: March 2021

AbstractSuccessful pursuit and evasion require rapid and precise coordination of navigation with adaptive motor control. We hypothesize that the dorsal anterior cingulate cortex (dACC), which communicates bidirectionally with both the hippocampal complex and premotor/motor areas, would serve a mapping role in this process. We recorded responses of dACC ensembles in two macaques performing a joystick-controlled continuous pursuit/evasion task. We find that dACC carries two sets of signals, (1) world-centric variables that together form a representation of the position and velocity of all relevant agents (self, prey, and predator) in the virtual world, and (2) avatar-centric variables, i.e. self-prey distance and angle. Both sets of variables are multiplexed within an overlapping set of neurons. Our results suggest that dACC may contribute to pursuit and evasion by computing and continuously updating a multicentric representation of the unfolding task state, and support the hypothesis that it plays a high-level abstract role in the control of behavior.
Market-oriented job skill valuation with cooperative composition neural network
Authors: Sun Ying , Zhuang Fuzhen , Zhu Hengshu , Zhang Qi , He Qing , Xiong Hui 
Published: March 2021

AbstractThe value assessment of job skills is important for companies to select and retain the right talent. However, there are few quantitative ways available for this assessment. Therefore, we propose a data-driven solution to assess skill value from a market-oriented perspective. Specifically, we formulate the task of job skill value assessment as a Salary-Skill Value Composition Problem, where each job position is regarded as the composition of a set of required skills attached with the contextual information of jobs, and the job salary is assumed to be jointly influenced by the context-aware value of these skills. Then, we propose an enhanced neural network with cooperative structure, namely Salary-Skill Composition Network (SSCN), to separate the job skills and measure their value based on the massive job postings. Experiments show that SSCN can not only assign meaningful value to job skills, but also outperforms benchmark models for job salary prediction.