bluuebunny/crossref_metadata_2025_split huggingface dataset:
Understanding the relationship between organizational culture and inbound open innovation
Authors: Barjak Franz , Heimsch Fabian 
Published: November 2021

PurposeThe relationship between corporate culture and inbound open innovation (OI) has been limited to two sub-constructs: a culture for openness and an innovation culture, but until now a richer conceptualization of corporate culture is missing.Design/methodology/approachThe authors apply Quinn and Rohrbaugh's (1983) competing values framework and regress these together with company internal and external control variables on five measures of inbound OI, reflecting product innovation, process innovation and the sourcing of innovation activities. The authors use data from a survey of more than 250 Swiss companies, primarily SMEs.FindingsThe importance of the firms' market environments suggests that the results are affected by the specific situation in which the firms found themselves at the time of the survey: after a strong currency shock, inbound OI activities seem to be a reaction to external pressure that favored planning and rule-oriented (formal) cultures to implement cost-cutting process innovations.Practical implicationsCompanies should develop a vision and a strategy, ensure open and transparent communication, have suitable reward and support mechanisms in place, adjust structures and processes, and institutionalize and formalize any change whenever they are confronted with a situation that requires a quick reaction and an adjustment to their degree of openness.Originality/valueThe paper clarifies the relationship between cultural traits and inbound OI, using a well-established understanding of corporate culture and differentiating between innovation types. It points to the importance of the external environment in order to understand the role of culture.
Genetic variation at the p53 locus of two ecologically divergent Microtus pine voles: identification of molecular markers for species assignment
Authors: QUINA Ana Sofia , TAVANEZ João Paulo , MATHIAS Maria da Luz 
Published: November 2021

AbstractThe Lusitanian (Microtus lusitanicus) and the Mediterranean (Microtus duodecimcostatus) pine voles are recently diverged sister species endemic of the Iberian Peninsula that can be identified with ecological and morphological characters, but in areas where the 2 species co‐occur, species designation may be difficult. Genetic discrimination between M. lusitanicus and M. duodecimcostatus has not been achieved yet possibly because of their estimated recent split and an evolutionary history that includes inter‐species gene flow. Following our previous observations on exons 5–7 of the p53 gene, here we analyze the potential use of the p53 genomic region as a discrimination marker of these species by extending our analyses to several kb upstream and downstream of the p53 gene and characterizing the degree of genetic differentiation in 7 markers within this region. Additionally, we fully sequenced the P53 protein of both species. We observed: (i) generally high differentiation in this region; (ii) M. duodecimcostatus showed in general higher values of nucleotide and haplotype diversities; (iii) the concatenated phylogenetic tree separates the 2 species; (iv) the 2 P53 proteins only differ in 1 amino acid; (v) 4 of the markers, 2 in p53, one in Atp1b2, and another in Wrap53, contain species‐specific genetic variation thus allowing a reliable discrimination between specimens from both species, irrespective of sampling location or introgression status. We provide additional data on the putative role of p53 in the evolution of these species and present researchers with a fast and cost‐effective resource for M. lusitanicus and M. duodecimcostatus identification.
Comparison of apical debris extrusion during root canal preparation in primary molars using different file systems: an in vitro study
Authors: Mohammadi Davood , Mehran Majid , Frankenberger Roland , BabeveyNejad Newsha , Banakar Morteza , Haghgoo Roza 
Published: November 2021

AbstractThis study aimed to compare the amount of debris extrusion of four endodontic systems made of Nickle‐Titanium alloy. This in vitro study was done on 80 extracted primary molars. They were selected by cone‐beam computed tomography and randomly divided into four groups (n = 20) to be prepared to the apical size of 25 by one of the systems: Reciproc, Protaper Universal, Neolix, or Hyflex CM. Debris was collected into Eppendorf microtubes and placed in an incubator to evaporate the washing solution. Debris was weighed by a digital scale of 0.01 g precision. Data were statistically analysed using SPSS software. Tukey’s comparison was used to determine the difference between the four file systems (α = 0.05). Debris extrusion after Reciproc preparation (0.00320) was significantly higher than the other (P < 0.05), with no significant difference having been observed among the other systems (P > 0.05). It can be concluded that all systems under investigation exhibited debris extrusion.
Leaps ahead in law but not in practice: Why we need to train in second trimester abortion care
Authors: Hudspith Anna , Paterson Helen , Caldwell Coleen , Whiting Rosie 
Published: November 2021

BackgroundAbortion care has always been controversial, with health professionals worldwide continually working to offer well‐rounded safe services. Key improvements in New Zealand since abortion law reform include the ability to self‐refer, no formal certification under 20 weeks gestation, and change to the indications for abortion after 20 weeks. Nationally, we know that the second trimester abortion incidence is stable, and will therefore require an ongoing workforce to sustain the service.AimsTo document the current second trimester workforce for medical and surgical abortion in New Zealand, and examine their training and practice.Materials and MethodsAnonymous non‐discriminatory snowball survey covering the domains of demographics, barriers to abortion care, abortion training, abortion provision and procedure specifics using Qualtrics software.ResultsEleven practitioners currently perform dilation and evacuation, and 33 wish to. Current providers have between zero and three other colleagues to assist them in service provision. Most learned by an informal apprenticeship model and operate relatively infrequently. There is variance in the cervical preparation and evacuation procedure as well as skillset and/or willingness for later gestations. Fifty‐nine practitioners' units currently provide medical abortion, and 62 wish to. There is more coherence in the regime of medical abortion, although the availability of this is affected by gestation and location.ConclusionFor most women requesting second trimester abortions, additional time, cost and stress is still very much the status quo. District Health Boards need to prioritise training and workforce planning to ensure the availability of this essential service.
Chambered warm moist air eyelid warming devices – a review
Authors: Magno Morten Schjerven , Olafsson Jonatan , Beining Marie , Moschowits Emily , Lagali Neil , Wolffsohn James S. , Craig Jennifer P. , Dartt Darlene A. , Vehof Jelle , Utheim Tor P. 
Published: November 2021

AbstractBackgroundEyelid warming is an important treatment for meibomian gland dysfunction (MGD). Specialized chambered devices, using warm moist air have been developed.PurposeTo critically evaluate the literature on the safety and efficacy of chambered warm moist air devices in MGD treatment and pinpoint areas of future research.MethodsPubMed and Embase were searched on 06 June 2021. The search term was ‘(warm OR heat OR steam OR goggle OR spectacle OR moist air) AND (meibomian OR MGD OR blepharitis OR eyelid OR dry eye OR DED)’. All relevant articles with available English full text were included.ResultsEighteen articles assessing the application of chambered warm moist air eyelid warming devices were identified. In single‐application studies, steam‐based eyelid warming increased the eyelid temperature and improved symptoms, lipid layer thickness, and tear film breakup time (TBUT). In treatment studies, the steam‐based devices improved TBUT and symptom scores. However, in the only randomized controlled trial (RCT) comparing chambered steam‐based heat to hot towel treatment, there was no difference between groups for the primary outcome measure; the proportion of subjects noting symptom improvement after 4 weeks.ConclusionCurrently available chambered warm moist air eyelid warming devices are safe and effective at raising eyelid temperature to therapeutic levels and improving signs and symptoms of dry eye. However, it is not clear if they provide a greater benefit than other eyelid warming therapies. Further well‐conducted RCTs comparing moist and dry heat devices should be conducted on patients across the range of DED severities and subtype spectrum.
Looking deeper into ocular surface health: an introduction to clinical tear proteomics analysis
Authors: Nättinen Janika , Aapola Ulla , Nukareddy Praveena , Uusitalo Hannu 
Published: November 2021

AbstractOcular surface diseases are becoming more prevalent worldwide. Reasons for this include the ongoing population ageing and increasing use of digital displays, although ophthalmologists have a wide selection of tools, which can be implemented in the evaluation of the ocular surface health, methods, which enable the in‐depth study of biological functions are gaining more interest. These new approaches are needed, since the individual responses to ocular surface diseases and treatments can vary from person to person, and the correlations between clinical signs and symptoms are often low. Modern mass spectrometry (MS) methods can produce information on hundreds of tear proteins, which in turn can provide valuable information on the biological effects occurring on the ocular surface. In this review article, we will provide an overview of the different aspects, which are part of a successful tear proteomics study design and equip readers with a better understanding of the methods most suited for their MS‐based tear proteomics study in the field of ophthalmology and ocular surface.
Long‐term outcome of patients receiving haematopoietic allogeneic stem cell transplantation as first transplant for high‐risk Hodgkin lymphoma: a retrospective analysis from the Lymphoma Working Party‐EBMT
Authors: Gutiérrez‐García G. , Martínez C. , Boumendil A. , Finel H. , Malladi R. , Afanasyev B. , Tsoulkani A. , Wilson K. M. O. , Bloor A. , Nikoloudis M. , Richardson D. , López‐Corral L. , Castagna L. , Cornelissen J. , Giltat A. , Collin M. , Fanin R. , Bonifazi F. , Robinson S. , Montoto S. , Peggs K. S. , Sureda A. 
Published: November 2021

SummaryWe analysed long‐term outcome of patients receiving haematopoietic allogeneic stem cell transplantation (allo‐HSCT) as a first transplant for high‐risk Hodgkin lymphoma (HL). One hundred and ninety patients were included in this study, 63% of them had previously received brentuximab vedotin and/or checkpoint inhibitors. Seventy patients (37%) received an unrelated donor allo‐HSCT, 99 (51%) had myeloablative conditioning (MAC) and 60% had in vivo T‐cell/depleted grafts (TCD). The 100‐day cumulative incidence (CI) of grade II‐IV acute graft‐versus‐host disease (GVHD) was 25% and the 3‐year CI of chronic GVHD was 38%. The 3‐year CI of non‐relapse mortality (NRM) and relapse rate were 21% and 38% respectively. After a median follow‐up of 58 months, 3‐year overall survival (OS) and progression‐free survival (PFS) were 58% and 41% respectively. Multivariate analysis showed that, in comparison to reduced‐intensity conditioning regimens with or without TCD, MAC using TCD had similar NRM and a lower risk of relapse leading to significantly better OS and PFS. MAC without TCD was associated with higher NRM and worse survival outcomes. These results suggest that in patients with high‐risk HL and candidates of allo‐HSCT, a MAC strategy with TCD might be the best option.
An exploration of the Personal Relationship Advisory Group in a community learning disability service: A service development project
Authors: Coleman Sophie Elizabeth , Sharrock Emma 
Published: November 2021

Accessible summary

The project aimed to explore discussions from the Personal Relationship Advisory Group (PRAG) meetings in a community adult learning disability team to influence the development of new relationship resources.

All meeting minutes within a 12‐month period were analysed to find themes.

The themes suggest the importance of the service looking at the whole person, such as their physical, emotional and social well‐being, when there are relationship concerns.

New resources that focus on personal sexuality, different types of relationships and Internet safety may be of benefit to the service.

Resources for carers may also be useful, such as helping carers to support people with learning disabilities to safely access relationships online.

AbstractBackgroundAdults with learning disabilities often face barriers when accessing relationships and can require additional support. The Personal Relationship Advisory Group (PRAG) is a provision in a community learning disability service in North England, which offers multidisciplinary advice regarding relationship concerns. The current project aimed to identify common themes within PRAG to influence the development of new resources in the service.Materials and MethodsAll meeting minutes within a 12‐month period were analysed using thematic analysis. There were a total of 16 minutes, which discussed 11 people with learning disabilities. This included six females and five males with a mean age of 30 (SD = 14.97).ResultsIndividuals often had limited opportunity to develop relationships. There was a lack of understanding of sex and of how to behave appropriately in different types of relationships, with a need for individualised, accessible education. The Internet was commonly used to seek relationships, with many concerns regarding safety from carers or family. There were some unhelpful responses from others, such as the implementing of restrictions. Factors that may have an impact on the person's overall well‐being, such as their health, social issues and trauma, were often discussed.ConclusionsThe identified themes suggest the need for the service to take a holistic, biopsychosocial and individualised approach when supporting individuals with any relationship concerns. A multidisciplinary approach and collaboration with the individual and family/carers is key. It may be useful for the service to develop resources on topics such as personal sexuality, different types of relationships and Internet safety. Carer‐specific resources would also be beneficial, such as advice on how to safely support individuals to seek relationships on the Internet.
Walking a Fine Line: The Struggle for Parent Advocacy in the NYC Child Welfare System☆
Authors: Castellano Viola 
Published: November 2021

AbstractThis article investigates parent advocacy in the child welfare system amongst families living in low‐income and racialized urban areas, those most impacted by this system. Drawing from my fieldwork experience at the community‐based organization Child Welfare Organizing Project (CWOP) in East Harlem, New York, I interrogate the political trajectory of the organization, its practices, and its purpose. I analyze how the decision parents make to advocate is tied to the injustice, stigma, and surveillance they—and especially mothers—experience in the child welfare system. While exploring how parenting and its political dimension are reshaped for disfranchised mothers through advocacy, I describe the “fine line” between compliance and resistance that CWOP has walked throughout its history to preserve its existence. This article illustrates how this form of activism takes place within a fragmented and increasingly privatized welfare regime, in which community‐based organizations struggle for their right to remain political actors and not be overtaken by the logic of service provision. Through my analysis, I aim to contribute to anthropological understandings of the forms of political agency taken up by stigmatized subjects in their interactions with the state, and the limits the state demonstrates in “hearing” their claims and requests for change.
Phosphorus speciation and distribution in a variable‐charge Oxisol under no‐till amended with lime and/or phosphogypsum for 18 years
Authors: Firmano Ruan F. , Colzato Marina , Alleoni Luís R. F. 
Published: November 2021

AbstractLong‐term management with lime and/or phosphogypsum (PG) can change phosphorus (P) forms across the soil profile. In this study, we used synchrotron‐based spectroscopy and sequential chemical fractionation to investigate P chemical species after long‐term (18 years) application of amendments in a subtropical Oxisol. The availability of nutrients increased with the combined use of lime and PG and a stratification of attributes was identified due to long‐term broadcast applications. X‐ray absorption near edge structure (XANES) spectra profiles revealed the predominance of P bounded to haematite (Hm) (48% on average) and also P bound to kaolinite (32% on average) species. Low proportions (16%) of calcium‐phosphates in the uppermost soil layer (0–5 cm) were found in the treatment that received high calcium (Ca) inputs by lime and PG broadcast. Few correlations were identified between the proportions of P species obtained by XANES and P fractions operationally defined by sequential chemical fractionation (SF). Our results suggest that P‐species bound to kaolinite can store stable P forms, which correlated (p < 0.05) with the residual P fractions obtained by SF, highlighting the importance of kaolinite as a legacy P store in Oxisols.Highlights
Lime and phosphogypsum broadcast under no‐till improve soil fertility and P availability.
Labile and moderately labile P fractions were the only ones influenced by lime and/or phosphogypsum.
Proportions among P bounded to Fe‐ and Al‐(hydr)oxides with different structural may be affected by long‐term Al‐suppressors.
P‐species bounded to kaolinite may store stable P forms in Oxisols.
Metabolic dysfunction‐associated fatty liver disease and liver fibrosis: Prevalence and associated factors in the middle‐aged and older US population
Authors: Yang Sheng , Cheng Jiawen , Zhang Rui , Sun Huiwen , Zhang Hui , Lyu Sali , Duan Weiwei 
Published: November 2021

AbstractAimThe global burden of chronic liver disease is substantial. Limited studies have reported the prevalence of metabolic dysfunction‐associated fatty liver disease (MAFLD) and liver fibrosis among middle‐aged and older people. Therefore, we aimed to determine the nationwide prevalence of and associated factors for MAFLD and fibrosis in adults aged 45–79 years from the United States.MethodsThis cross‐sectional study utilized data from the 2017–2018 cycle of the National Health and Nutrition Examination Survey conducted with a nationally representative sample of the civilian, noninstitutionalized US population. Hepatic steatosis and fibrosis were assessed by transient elastography with controlled attenuation parameter and liver stiffness measurement, respectively.ResultsA total of 1186 eligible participants aged 45–79 years were finally included in the analyses. The estimated prevalence of MAFLD, significant fibrosis (F ≥ F2), and advanced fibrosis (F ≥ F3) was 48.6% (95% confidence interval [CI], 43.1%–54.0%), 9.5% (95% CI, 6.8%–12.7%), and 6.7% (95% CI, 4.1%–10.1%), respectively. Multivariable logistic regression revealed an increased MAFLD predisposition in subjects with metabolic disorders including overweight/obesity, abdominal obesity, hypertension, and diabetes mellitus. Moreover, the presence of depression was an independent and strong predictor of MAFLD risk (odds ratio = 3.23; 95% CI, 1.37–7.11). Elevated liver enzymes, hypertension, diabetes mellitus, hepatitis virus infection, and steatosis were associated with a high risk of significant fibrosis.ConclusionsNewly defined MAFLD is highly prevalent in the US middle‐aged and older population. Approximately 1 in 10 people has significant liver fibrosis. In addition to metabolic disorders, the presence of depression potentially increases the risk of MAFLD.
Concept analysis of shame in nursing
Authors: Jaeb Michael A. 
Published: November 2021

AbstractNurses can facilitate opportunities for patients who feel shame to experience healing in their mental health. Disciplines such as psychology have extensive shame research, yet nursing may provide a unique perspective to bolster research on shame. The objective of this analysis is to examine the use of shame as a concept in nursing literature. This review was guided by Beth Rodgers’ Evolutionary approach to concept analysis. Rodgers' approach entails investigating attributes, related terms, surrogate terms, antecedents, and consequences of shame; and examining the use of the concept shame over time to determine if its use changed. Sampled literature came from Cumulative Index to Nursing and Allied Health Literature Plus with Full Text, PubMed, Web of Science, and Health Source: Nursing/Academic Edition. The final sample used for analysis included 334 sources published between 1993 and 2020. The use of shame did not change during these years. Attributes were negative sense of self, feeling worthless, and feeling vulnerable. There were no surrogate terms and three related terms: guilt, humiliation, and embarrassment. Antecedents were trauma, stigma, and perception of moral wrongdoing. Consequences included healthcare avoidance, social withdrawal or isolation, negative coping mechanisms, resilience, lifestyle changes, and healthy coping. There is a discrepancy between the conceptualization and use of shame in nursing and other disciplines. Other disciplines, such as psychology, provide more direction about how interpersonal interactions can elicit or alleviate feelings of shame. Nurses can apply this conceptualization in their clinical practice to support patients experiencing shame.