bluuebunny/crossref_metadata_2025_split huggingface dataset:
Revealing Resistive Switching of Phase Transitions in an Al‐Doped Single Crystal of VO2 by DC and Pulsed Electrical Measurements
Authors: Patlagan Larisa , Reisner George M. , Fisher Bertina 
Published: December 2024

AbstractThe simple phase diagram of pure VO2 consisting of an insulating monoclinic M1 phase and a metallic tetragonal R phase with a steep insulator‐metal‐transition (IMT) at TIMT = 340 K, is enriched by two additional insulating phases, a triclinic (T) and a monoclinic (M2) and multiple phase transitions, when strained or doped with M3+ions (M = Ga, Al, Cr, Fe, Mg). Under low‐current R(T) measurements, the T(M1 → M2) and IMT are the only once detected by X‐ray diffraction that show reproducible resistive switching (RS) and hysteresis typical of first‐order transitions. Following the surprising detection of the RS associated with the M1→T transition induced by a high electric field in Ga‐, Al‐, and Cr‐doped VO2 crystals, we attempted to uncover those associated with additional transitions in Al‐doped VO2 nanostructures, as reported by Strelcov et al., Nano Letters 2012. Reported herein is the investigation of a single crystal of nominal Al0.01V0.99O2 composition, by repeated direct current (DC) and pulsed IV measurements at fixed ambient temperatures below and at room temperature (RT). RS associated with the various phase transitions appeared in the nonlinear I(V) regime induced by self‐heating (Joule heating), including all those that are absent under low‐electric‐current measurements.
Ground Penetration Radar and Magnetic Surveys for Archaeogeophysical Prospecting at the Seti I Temple at Abydos, Sohag, Egypt
Authors: Abudeif Abdelbaset M. , Abdel Aal Gamal Z. , Peláez José A. , Sawires Rashad , Masoud Marwa M. , Elnassari Ahmad , Mansour Khamis K. , Gaber Hossameldeen A. , Mohammed Mohammed A. 
Published: December 2024

ABSTRACTThis paper presents an archaeogeophysical prospection in Abydos, a rich archaeological site including royal monuments and tombs from multiple periods of Ancient Egypt. Abydos is the most important burial site of ancient Egypt, having a history extending back about 7500 years. Near‐surface geophysical techniques, particularly ground magnetic and ground‐penetrating radar (GPR) surveys, have been used to discover hidden ancient archaeological objects that will help with the site's long‐term development. The main objective of this work was the depth estimation and geometry determination of the buried archaeological objects southwest Seti I temple, such as walls, tombs and other features. A proton‐precession magnetometer (G‐857) and an SIR‐4000 equipment with an antenna of 200 MHz were used as instrumentation for the magnetic and GPR surveys, respectively. A final output is a total magnetic intensity (TMI) anomaly map, which has undergone extensive filtering to separate the residual components related to the shallow objects that could potentially serve as archaeological targets from the regional components of the deeper anomalies. Depth was estimated using source parameter imaging and 3D Euler deconvolution. The qualitative interpretation of the obtained magnetic maps reveals that there are clusters of anomalies that could indicate archaeological remains. On the other hand, the GPR findings reveal the presence of reflection hyperbolae within the measured profiles coinciding with the magnetic anomalies, supporting the probable existence of archaeological buried objects, which need to be confirmed by excavation. The main depths of these objects range approximately between 1 and 3 m. Our results bring new light on yet uninvestigated archaeological features at Abydos, paving the road to renewed archaeological research in this area.
Functional Expression and Construction of a Self‐Sufficient Cytochrome P450 Chimera for Efficient Steroidal C14α Hydroxylation in Escherichia coli
Authors: Ke Xia , Dong Hong‐Duo , Zhao Xi‐Man , Wang Xin‐Xin , Liu Zhi‐Qiang , Zheng Yu‐Guo 
Published: December 2024

ABSTRACTC14‐functionalized steroids enabled diverse biological activities in anti‐gonadotropin and anticancer therapy. However, access to C14‐functionalized steroids was impeded by the deficiency of chemical synthetic methods. Recently, several membrane‐bound fungal cytochrome P450s (CYPs) have been identified with steroid C14α‐hydroxylation activity. However, the lack of efficient heterologous overexpression strategy hampered their further characterization and molecular engineering. In the present study, sequences of fungi‐derived CYP genes encoding putative 14α‐hydroxylase were selected and bioinformatically analyzed. Substitution of the N‐terminal hydrophobic helix by a soluble maltose binding protein tag significantly enhanced the soluble expression level in Escherichia coli. A novel CYP originated from Bipolaris oryzae was discovered with high steroidal C14α‐hydroxylation activity when coupled with the redox partner CPRlun. A catalytically self‐sufficient chimeric CYP‐CPR was built by intramolecular fusion, and the electronic transfer rate was improved. A coenzyme NADPH regeneration system was finally constructed by the co‐expression of glucose dehydrogenase. The developed soluble multi‐enzyme cascade biotransformation system supported the selective C14α‐hydroxylation toward progesterone with a final titer of 34.54 mg/L, the highest level achieved in E. coli‐based heterologous expression system. This study provides insightful ideas on the functional expression of fungi‐derived CYPs and promises an efficient C14α‐hydroxylation system for steroidal drugs through protein engineering.
Nanoparticle‐based drug delivery system with enhanced loading and targeting performance: A brief account
Authors: Oh Jun Yong , Yang Gyeongseok , Choi Eunshil , Ryu Ja‐Hyoung 
Published: December 2024

AbstractFor the construction of a nanoparticle (NP)‐supported drug delivery system (DDS), loading efficiency, stable encapsulation, and targeted delivery are considered crucial to achieve a high therapeutic outcome of the resulting system. Conventionally, NPs are functionalized with desired molecules via covalent interactions, which do not only limit the intraparticle space for drug loading but also cause significant loss of the preloaded drug through the multistep chemical reactions. Furthermore, NPs with covalently modified surface are easily surrounded with biomolecules during blood circulation, and their accumulation in a target site becomes considerably hampered. Keeping these issues in mind, we herein summarize the recently reported unconventional strategies to prepare a more powerful DDS with enhanced loading and targeting ability, by installing a noncovalent polymeric gatekeeper or surface‐protective biomolecular layer on the NP surface.
Extrudability of geopolymers and control of the formed networks by zeta potential and NMR spectroscopy
Authors: N'Cho Wilfried Cyrille , Gharzouni Ameni , Sobrados Isabel , Jouin Jenny , Aimable Anne , Rossignol Sylvie 
Published: December 2024

AbstractIn this study, the local‐scale structure of geopolymers shaped by extrusion or 3D printing was investigated and correlated to the reactivity of the raw materials. The reactivity of the different metakaolin mixtures was evaluated using zeta potential measurements with different alkali silicate solutions, followed by shaping via 3D printing; additionally, the different networks formed were identified via NMR spectroscopy. The results showed that in the presence of weakly reactive basic solutions, the Al(OH)4− species were released in low amounts due to an increase in the polymerized silicate species in the solution, resulting in a low zeta potential in absolute value. Conversely, for more reactive solutions, the silicate species were more depolymerized, and the siliceous and aluminous metakaolin species were more easily released in solution, resulting in increasingly low zeta potential values. Some samples were 3D printed with metakaolin mixtures using different printers and silicate solutions (K, KNa) with alkaline cation concentrations of [M] > 2.8 M in the mixtures; here, the metakaolin zeta potential values were greater than −50 mV, and the local‐scale structure consisted of more than 50% geopolymer networks (Q4(3Al) + Q4(2Al)).
Synthesis, Characterization and Reactivity of a Base‐Stabilized Dialane(4) Supported by Double Layer Nitrogen–Phosphorus Ligands
Authors: Chen Pengfei , Li Yafei , Zhao Qianyi , Zhu Congqing , Zhu Qin 
Published: December 2024

Comprehensive SummaryWe synthesized a dialane(4) compound (2) stabilized by double‐layer N‐P ligands. Upon reduction with KC8, compound 2 demonstrates solvent‐dependent reactivity: in THF, it undergoes C—O bond cleavage to yield product [MeN(CH2CH2NPiPr2)2Al(CH2)4O]2K2; whereas in a THF/toluene mixture, it results in the activation of the methyl C—H bond in toluene, forming product [MeN(CH2CH2NPiPr2)2AlH]2K2. We propose that these reactions involve an “Al(I)” intermediate, which facilitates oxidative addition with either the C—O bond of THF or the C—H bond of toluene.
Tubules, Rods, and Spirals: Diverse Modes of SepF‐FtsZ Assembling
Authors: Choudhury Jagrity , Chaudhuri Barnali N. 
Published: December 2024

ABSTRACTZ‐ring formation by FtsZ, the master assembler of the divisome, is a key step in bacterial cell division. Membrane anchoring of the Z‐ring requires the assistance of dedicated Z‐ring binding proteins, such as SepF and FtsA. SepF participates in bundling and membrane anchoring of FtsZ in gram‐positive bacteria. We report in vitro biophysical studies of the interactions between FtsZ and a cytoplasmic component of cognate SepF from three different bacteria: Mycobacterium tuberculosis, Staphylococcus aureus, and Enterococcus gallinarum. While the cytosolic domain of SepF from M. tuberculosis is primarily a dimer, those from S. aureus and E. gallinarum polymerize to form ring‐like structures. Mycobacterial SepF helps in the bundling of FtsZ filaments to form thick filaments and large spirals. On the other hand, ring‐forming SepF from the Firmicutes bundle FtsZ into tubules. Our results suggest that the oligomeric form of SepF directs how it bundles FtsZ filaments.
Analyzing Spinal Cord Stimulation With Different Electrode Configurations: A Numerical Study
Authors: Aydin Elif Feyza , Zengĺn Reyhan 
Published: December 2024

ABSTRACTSpinal cord stimulation (SCS) represents a therapeutic approach for chronic pain management in patients refractory to conventional treatments. By implanting electrodes in the epidural space, SCS aims to mitigate pain transmission to the brain through electrical stimulation, often resulting in sensory perceptions such as paresthesia. This study investigates the influence of electrode configurations on electrical parameters, including current density and electric potential, within the spinal cord environment. Utilizing computational models of the spinal canal incorporating components such as epidural fat, cerebrospinal fluid (CSF), gray matter, and white matter, our analysis explores the distribution of electric potential and current density. Specifically, configurations employing four and nine electrodes are evaluated under both direct current (DC) and alternating current (AC) stimulations. For DC stimulations at currents of 1, 5, and 10 mA, our findings indicate that the four‐electrode model generated current density values in epidural fat ranging from 107.90 to 130.98 mA/cm2 and electric potential values ranging from 3.51 to 4.78 V. Similarly, the nine‐electrode model produced current density values ranging from 92.51 to 223.61 mA/cm2 and electric potential values ranging from 1.27 to 7.83 V under the same conditions. The results demonstrate a proportional relationship between applied current, current density, and electric potential. Furthermore, our investigation reveals a gradual decrease in electrical potential and current density from the epidural space to the gray matter. Discussions encompass the safety implications of these findings, examining whether the observed electrical parameters remain within tolerable limits for patient well‐being. Additionally, the study explores the effects of AC stimulation across frequencies ranging from 250 Hz to 10 kHz, revealing an inverse correlation between frequency and charge parameters. Specifically, higher frequencies corresponded to reduced charge per phase and charge density, underscoring the frequency‐dependent nature of these electrical properties.
Color Palette Generation From Digital Images: A Review
Authors: Gao Yafan , Liang Jinxing , Yang Jie 
Published: December 2024

ABSTRACTColor palette is a critical component of art, design, and lots of applications, providing the basis for organizing and utilizing colors to achieve specific objectives. However, generating color palettes from digital images presents unique challenges due to the complexity of colors in images. This review comprehensively investigates various techniques for generating color palettes from digital images and provides a thorough classification and discussion of these techniques from multiple perspectives. A color space must be selected to generate a color palette, and a generation method must be employed. This paper offers a concise overview of color spaces, an introduction to current palette generation methods, and an analysis of the metrics used to evaluate color differences between palettes. The review encompasses traditional manual methods and computer‐aided automation methods, further categorized as histogram‐based, clustering‐based, and neural network‐based methods. Discussion on the strengths, weaknesses, and applicability of existing methods are presented, and also opportunities for future research to enhance color palette generation from digital images are identified.
Exploring the Link: A Systematic Review and Meta‐Analysis on the Prevalence and Association Between Refractive Errors and Intermittent Exotropia
Authors: Mohammad Najah K. , Rajab Ibrahim Ali , Mutar Mohammed Tareq , Ismail Mustafa 
Published: December 2024

ABSTRACTBackground and AimsRefractive errors and intermittent exotropia are prevalent conditions in pediatric populations, impacting visual development and quality of life. Despite the co‐occurrence of conditions such as myopia, hypermetropia, and astigmatism with strabismus, comprehensive analyses of their coexistence are limited. This study aims to investigate the prevalence and characteristics of refractive error among children with intermittent exotropia and find the correlation between the angle of deviation for far and near with factors like mean spherical equivalent and age.MethodsA systematic review and meta‐analysis were conducted in accordance with PRISMA guidelines. PubMed and Scopus databases were searched up to February 13, 2024. Inclusion criteria encompassed studies detailing clinical presentation, management strategies, and outcomes, while exclusion criteria eliminated review articles, conference abstracts, animal research, and studies with inadequate clinical information. Data extraction and quality assessment were independently performed by multiple reviewers, with discrepancies resolved through consensus. Forest plot was used to show the mean spherical equivalent and the angle of deviation, while publication bias was demonstrated using funnel plot with Egger test.ResultsThe search yielded 932 articles, with 23 meeting the inclusion criteria. Studies represented four geographical regions, with a combined sample size of 5407 participants aged 3–10 years. The mean refractive errors varied widely, with an overall pooled mean of −1.787 (95% CI: −5.392 to 1.818). Overminus lens therapy and surgical interventions were common management strategies, with surgery prevalent in cases with higher distant angle deviation. The myopia was more prevalent than hypermetropia (26.82%/16.10%). Meta‐regression showed that the mean spherical equivalent had a significant effect on the angle of deviation far and near.ConclusionThere was a significant correlation between myopia and intermittent exotropia in Middle Eastern and Asian pediatric populations. Myopia is notably more prevalent with significant effect of mean spherical equivalent on near‐angle deviation.
CEO Overconfidence and Corporate Tax Strategy
Authors: Hsu Wei , Lee Yvonne 
Published: December 2024

ABSTRACTLiterature in accounting, economics, and corporate finance explores how top corporate executives’ personal traits and psychological biases affect firm decisions. This study focuses on one specific dimension of CEO personality: overconfidence and examines how CEO overconfidence influences corporate tax strategies. Overconfident executives tend to expect good outcomes due to optimistic bias or overestimation of their ability to bring about success. Therefore, they tend to overestimate the returns on investment projects and overinvest. We postulate that overconfident CEOs are inclined to seek risky tax planning activities to generate additional cash streams to make up for those projects not producing as much cash flow as originally expected. We find our three measures of overconfidence to be positively correlated with the book‐tax difference (BTD). Our main overconfidence measure, proxied by CEOs delaying exercising their stock options, is negatively correlated with the cash effective tax rate (CETR), consistent with our prediction that overconfident CEOs exhibit more tax aggressiveness to preserve cash. Additionally, we test whether corporate governance affects corporate tax strategies and show that overconfident CEOs continue to have a negative effect on cash‐effective tax rates regardless of the strength of board governance.
Expressive Suppression of Emotions in Bulimia Nervosa: An Electroencephalography Study
Authors: Desdentado Lorena , Pollatos Olga 
Published: December 2024

ABSTRACTObjectivePrevious research has found dysfunctional emotion regulation in bulimia nervosa (BN), including self‐reported greater habitual use of maladaptive strategies such as suppression than in healthy individuals. However, there is no evidence on the performance in the implementation of expressive suppression in BN. The aim of this study was to investigate brain activity (in terms of ERP) and self‐reported ratings associated with expressive suppression of emotions elicited by positive and negative stimuli in women with BN.MethodEvent‐related potentials (ERP) were recorded from 23 female individuals with BN and 26 matched healthy controls. Participants were shown emotional pictures under two conditions: using facial suppression or attentively viewing. High‐density EEG was used to characterize the time course of emotion regulation.ResultsERP amplitudes varied significantly with valence, with positive (vs. neutral and negative) pictures eliciting larger ERP amplitudes. However, no significant differences in ERP were observed between the groups or conditions. The BN group reported lower self‐efficacy in implementing suppression compared to the control group, the latter with a positive correlation between the perceived self‐efficacy and the change in emotional arousal between conditions.DiscussionOur findings suggest that individuals with BN might have difficulties in monitoring the emotion regulation process compared to healthy individuals. This suggests that other processes (e.g., metacognitive difficulties, self‐esteem) rather than a failure to implement suppression, might underlie these results. However, further research is needed to validate this interpretation. Implications and directions for future research are discussed.
Clay Mineral–Hydrophobic Organic Compound Interactions in Miniaturized Adsorption Experiments: Exemplary Studies With Bentonites and Hexachlorobenzene
Authors: Böhm Leonard , Grančič Peter , Butzke Lilli P. , Kaufhold Stephan , Siemens Jan , Tunega Daniel , Gerzabek Martin H. 
Published: December 2024

ABSTRACTBackgroundHydrophobic organic compounds (HOCs) are ubiquitous in the environment. Especially halogenated HOCs can pose a major threat to human and environmental health. They show high affinity toward organic matter (OM), and adsorption processes are extensively investigated. Contrary, adsorption to minerals is often considered negligible, and knowledge on HOC interactions with clay minerals (CM) is still scarce.AimsWe aimed to apply an optimized method for the straightforward and sensitive quantification of HOC–CM interactions in miniaturized systems to quantify hexachlorobenzene (HCB) adsorption to native bentonites and to evaluate the influence of different mineral characteristics on adsorption.MethodsHOC–CM interactions were studied in miniaturized batch adsorption experiments with HCB as HOC representative and 21 native bentonites as CM phases. Additionally, five of the bentonites were used as sorbents after wet size fractionation (<2 µm) and homoionic cation exchange (Ca2+). Linear adsorption isotherms and solid–liquid distribution coefficients Kd were calculated after HCB analysis by solid‐phase microextraction (SPME) coupled to GC–MS.ResultsHCB adsorption to selected native bentonites showed a large variation over several orders of magnitude (log Kd 1.8–4.1). Size‐fractionation and Ca2+‐modification tended to slightly decrease the Kd values compared to the five corresponding native bentonites (log Kd: 1.9–3.8 vs. log Kd: 2.0–4.1). Most promising parameters for explaining adsorption strength by different CM characteristics were layer charge density (LCD) and cation exchange capacity (CEC). However, no single factor could be attributed to explain the observed variability of adsorption. The miniaturized batch adsorption method reduces the required amounts of purified CM and toxic chemicals while providing excellent sensitivity and reproducibility.ConclusionsHOC adsorption to native, smectite‐rich bentonites is mostly moderate but can be as high as adsorption to pure OM phases for some bentonites. The variation in adsorption appears to be controlled by a combination of several factors that might include additional factors not previously considered, especially for the bentonites with the strongest adsorption of HCB.
Harmonizing rhamnolipid biosurfactant production by halophilic Pseudomonas aeruginosa Pa84 by applying response surface methodology
Authors: Sharma Priyanka , Gautam Shantam , Joshi Siddhi , Debnath Mousumi 
Published: December 2024

AbstractBiosurfactants are gaining attention due to their biobased nature, including reduced toxicity and enhanced biocompatibility. This research work investigates the characteristics of the biosurfactant extracted from the halophilic strain Pa84 of Pseudomonas aeruginosa and optimizes its production using a statistical model. The identity of biosurfactant from P. aeruginosa strain Pa84 as rhamnolipid was determined by comparing the genomic sequences of strain Pa84 with high‐yielding strains of P. aeruginosa that produce rhamnolipid, through Fourier transform infrared and liquid chromatography‐mass spectrometer analyses, and by the presence of rhlA, rhlB, and rhlC genes in the genome of strain Pa84 that are responsible for the production of rhamnolipid. A methodical strategy using a time‐course assessment and statistical software optimized the production of rhamnolipids. After optimization using central composite design‐response surface methodology, the medium composition of 3.34 g/L of NH4Cl, 1.03 g/L of NaCl, and 4 g/L of glycerol were chosen, yielding 7.48 ± 0.0217 g/L of biosurfactant. These findings will help in the development of effective and sustainable bioprocess that produce rhamnolipid biosurfactants, for use in a variety of sectors.