bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical, anatomopathological, and immunohistochemical findings of a transitional cell carcinoma from nasal cavity, frontal and ethmoidal sinus with meningoencephalic invasion in a dog
Authors: Gorza Leonardo L. , Oliveira Ayisa R. , Porto Maryleydy G. , Santos Vania C. , Hardt Isabela , Maestri Luciana F. P. , Souza Tayse D. , Flecher Mayra C. 
Published: March 2021

Background: Primary neoplasms of the nasal cavity and sinuses are uncommon in domestic animals, most of which are of epithelial origin, being adenocarcinoma the most common tumor diagnosed in this region. Some malignant nasal cavity neoplasms may invade the brain causing clinical neurological signs, as well as purulent nasal secretion and epistaxis.
Case Description: A case of neoplasm is reported in a 14-year-old pincher presenting dyspnea, epistaxis, and neurological alterations. Necropsy revealed the presence of a mass in the oral cavity vestibule, and another in the whole nasal cavity with invasion of the cribiform plate, meninges and brain. Squamous cells carcinoma was diagnosed in the oral cavity and transitional carcinoma in the nasal cavity. The immunohistochemistry confirmed that the brain infiltration was of the same origin as the nasal cavity neoplasm.
Conclusion: The present report describes a rare case of transitional carcinoma of the nasal cavity as well as the frontal and ethmoidal sinuses with brain invasion, confirmed by immunohistochemistry. It is extremely important for veterinarians to include neoplasms in their differential diagnoses, when these animals show chronic respiratory signs and neurological alterations that do not improve with appropriate treatment, always associating with complementary exams, for correct diagnosis establishment and prognosis formulation.
Green Coffea robusta (Coffea canephora) from Lampung province effect toward free radicals in chickens infected with Salmonella enteritidis bacteria
Authors: Qosimah Dahliatul , Rosyidi Djalal , Radiati Lilik E. , Amri Indah A. , Prasetyo Dodik , Permata Fajar S. , Anisa Agri K. 
Published: March 2021

Background: Foodborne diseases are caused by acquired pathogenic bacteria such as Salmonella enteritidis. It causes an intestinal imbalance and the microbial toxins found in the gastrointestinal tract induce symptoms such as diarrhea. Coffee contains active ingredients such as antioxidants and is used as an anti-inflammatory agent by reducing pro-inflammatory cytokine levels in the body.
Aim: The purpose of this study was to determine the interaction between Lampung’s robusta coffee and tissue damage in chickens infected by S. enteritidis.
Methods: This study used first-day-old Isa brown layer chickens (n = 60), which were divided into five treatment groups. The negative control group consisted of healthy and normal chickens, whereas the positive control group consisted of chickens infected with S. enteritidis bacteria at a concentration of 108 CFU/ml. Groups T1, T2, and T3 were given coffee extract with doses of 500 mg/kg BW (low dose), 1,000 mg/kg BW (moderate dose), and 1,500 mg/kg BW (high dose), respectively, and then infected with S. enteritidis bacteria at a concentration of 108 CFU/ml. The coffee extract and bacteria were given orally via a feeding tube at a volume of 0.5 ml per chick. The extract was given for 14 days (from day 3 to day 16), and the bacteria were given on days 16 and 17. On day 18, the chickens were necropsied. The malondialdehyde (MDA) level was analyzed using one-way analysis of variance test with the GLM procedure (<0.05), while the tissue histopath was analyzed using a descriptive qualitative study to examine the ileal damage
Results: The results showed that the MDA levels (nmol/l) decreased in treatment groups T1, T2, and T3 compared to the positive control. On the contrary, we found improvements in the ileum histopathology of group T1 and T2 in the form of normal and regular intestinal epithelium arrangement of the ileum, long intestinal villi, and decreased total leukocytes.
Conclusion: Green coffee robusta has the potential to increase antioxidants and reduce inflammation in the small intestine of chickens infected with S. enteritidis.
Rabies in bovine: First case report of rabies in Al Jabal Al Akhdar, Libya
Authors: Sharif Monier , Arhaiem Aiman , Giadan Osama , Adam Abdulkarim , Abdalla Fawzia , Dayhum Abdunaser , Bengoumi Mohammed 
Published: March 2021

Background: Rabies is still one of the most neglected diseases in developing countries. It is endemic to North Africa, although rabies incidence in North Africa is certainly underestimated.
Case Description: On 18 December 2018 in the region of Al-Jabal Al-Akhdar, an 8-month-old calf died after a period of characteristic clinical symptoms of rabies. This is the first case of rabies in bovine which is confirmed through histopathological examination in the Laboratory of Veterinary Pathology, Omar Al-Mukhtar University. Microscopic examination clearly revealed encephalitis with the pathognomonic Negri bodies in the cerebellar neurons.
Conclusion: Since the characteristic lesions in the histopathological examination are sufficient to confirm the diagnosis and report infected cases, we recommend that the next version of the OIE Terrestrial Manual should add and clarify that the results of the use of histopathological techniques in the diagnosis of rabies are significant.
Little brainiacs and big dummies: Are we selecting for stupid, stout, or small dogs?
Authors: Rishniw Mark , Dewey Curtis W. 
Published: March 2021

Background: Brain size has been associated with intelligence of various orders and families of animals, leading to the concept of encephalization. Brain size scales with body weight between species within mammals to approximately the 0.67 power. However, within species, this scaling exponent appears to be much smaller (approximately 0.27 power).
Aim: We examined whether this relationship has persisted in dogs over the 120 years since this was originally observed.
Methods: Comparative cross-sectional study of magnetic resonance imaging (MRI) data obtained from 127 dogs, compared to historical data from 157 dogs and 24 non-dog canid species.
Results: Brain size in dogs measured by MRI had a scaling exponent virtually identical to that observed previously (0.24 vs. 0.26). However, the proportionality constant was smaller, suggesting that dogs in the study cohort had relatively smaller brains than the historical cohort. Absolute brain size appeared to have both a lower and upper limit in dogs. When compared to non-dogs canids, the most appropriate “representative” size for a “typical dog” when examining allometric scaling across Canidae appeared to be approximately 10–15 kg.
Conclusions: We interpreted the slight reduction in relative brain size to be a function of increased obesity in the study cohort compared to dogs examined 120 years ago. Further, we suggest that dog brains have a finite lower size limit. Finally, concepts of encephalization should not be applied to dogs.
Molecular characterization of duck plague virus from selected Haor areas of Bangladesh
Authors: Khan Kamrul Ahmed , Islam Md. Alimul , Sabuj Abdullah Al Momen , Bashar Md. Abul , Islam Md. Saiful , Hossain Md. Golzar , Hossain Muhammed Tofazzal , Saha Sukumar 
Published: March 2021

Background: Duck viral enteritis, commonly known as duck plague (DP), is an acute and contagious fatal disease in ducks, geese, and swans caused by the DP virus (DPV). It poses a serious threat to the growth of duck farming in the Haor (wetland) areas of Bangladesh.
Aim: This study aimed to detect the circulating DPV by molecular characterization, followed by phylogenetic analysis, targeting the UL30 gene in infected ducks from five Haor districts in Bangladesh and to observe the variation in the genome sequence between the field virus and vaccine strain of DPV.
Methods: A total of 150 samples (liver, 50; intestine, 50; and oropharyngeal tissue, 50) were collected from DP-suspected sick/dead ducks from 50 affected farms in Kishoreganj, Netrokona, B. Baria, Habiganj, and Sunamganj districts in Bangladesh. For the identification of DPV in collected samples, polymerase chain reaction (PCR) was utilized. Nucleotide sequences of the amplified UL30 gene were compared with those of other DPV strains available in GenBank.
Results: Of the 150 samples, 90 (60%) were found to be positive for DPV, as confirmed by PCR. Organ-wise prevalence was higher in the liver (72%), followed by the intestine (64%) and oropharyngeal tissue (44%). Regarding areas, the highest and lowest prevalence in the liver and intestine was observed in Habiganj and B. Baria, respectively, whereas the highest and lowest prevalence in the oropharyngeal tissue was observed in B. Baria and Habiganj, respectively. Two isolates, BAU/KA/DPV(B1)/2014 from Kishoreganj and BAU/KA/DPV(B4)/2014 from Sunamganj were sequenced, and phylogenetic analysis revealed that these isolates are evolutionarily closely related to Chinese isolates of DPV. Additionally, the isolates of DPV BAU/KA/DPV(B1)/2014 and BAU/KA/DPV(B4)/2014 showed the highest (98%) similarity to each other. The nucleotide sequence of the isolate BAU/KA/DPV(B1)/2014 exhibited higher nucleotide variability (246 nucleotides) than that of the vaccine strain (accession no. EU082088), which may affect protein function and additional drug sensitivity.
Conclusion: Based on the findings of the molecular study, it can be assumed that the Bangladeshi isolates and all Chinese isolates of DPV may have a common ancestry.
Effect of Web Causation Epidemiological Model on Preventive Behaviors of Diabetic Females with Genitourinary Tract Infection
Authors: Hemida Shaimaa A. E. , Ragheb Seham G. , El Sayied Hemat A. , Mohamed Hala M. 
Published: March 2021

Context: Genitourinary tract infection becomes a silent epidemic that devastated female life. It is closely interrelated with hyperglycemia, diabetes, and lack of awareness about personal hygiene care. All increase the susceptibility to various types of infections.
Aim: To assess the effect of web causation epidemiological model on preventive behaviors of diabetic females with genitourinary tract infection.
Methods: The study was conducted at a diabetic outpatient clinic in El Demerdash Hospital because it received clients from different areas and a high population rate. This study encompasses a purposive sample of 100 females. A quasi-experimental research design was selected. Data were collected using a structured interviewing questionnaire and preventive practice checklists to assess the knowledge and practices of the diabetic female.
Results: 69% of diabetic females had a family history of diabetes mellitus. 39% of them had satisfactory knowledge about causes that increased blood glucose in diabetic females shift to 81% at post-intervention. 35% of diabetic females had satisfactory knowledge about the function of the reproductive system at preprogram shift to 93% at post-program implementation. 34% of diabetic females had satisfactory knowledge about entry urinary tract infection methods at preprogram shift to 81% at post-program implementation. A highly statistically significant association between the presence of urine infection and application of web causation model (causative factors) such as lack of hygiene during menstruation, lack of hygiene before and after sexual intercourse, using mechanical contraceptive methods, increase the intake of salty foods, poor glycemic control and lack of personal hygiene with the results of urine analysis for infection.
Conclusions: Females exposed to the web causation epidemiological model exhibited better knowledge and preventive practices after exposure than their pre-intervention level. Apply the web-causation model at high population areas as slum areas on a large group of participants to improve awareness and practices regarding diabetes mellitus and genitourinary tract infection. Replicate the current study on a representative sample to improve the generalizability.
The Relationship between Self-Compassion, Self-Esteem and Suicidal Ideation among a Cohort of University Students
Authors: El-Masri Yosr M. , El-Monshed Ahmed H. 
Published: March 2021

Context: Self-compassion and self-esteem are positive personality traits that save us during life imperfection, so both can play a vital role in self-regulating behaviors to decrease suicidal ideation.
Aim: Explore the relationship between self-compassion, self-esteem, and suicidal ideation among a cohort of university students. Methods: Cross-sectional research design was used. This study was conducted at Al Delta University for Science and Technology- College of Engineering and Oral and Dental Medicine, Dhakahlia Governorate, Egypt. A convenient sample of 249 undergraduate university students was recruited. Self-Administered Questionnaire, Rosenberg’s Self-Esteem Scale (RSES), The Self-Compassion Scale-Short Form (SCS-SF), and The Suicidal Behavior Questionnaire-Revised (SBQ-R).
Results: 14% of the studied sample reported that they frequently have suicidal thoughts, while 28.12% reported that they sometimes have a suicidal attempt. Suicidal behavior was inversely and highly significantly correlated with self-esteem (P-value < 0.03), and also self-compassion was inversely and significantly related to suicidal behavior (P-value < 0.02). In contrast, self-compassion and self-esteem were positively and highly significantly correlated (P-value <0.001). Additionally, the higher mean score for having self-esteem and self-compassion was among students who had a sleep regularly (18.38±9.94 and13.8±3.10 respectively), and the students who are doing physical activities had the highest mean score (26.88±7.06 and 21.24±11.1 respectively) with statistically significant difference (P < 0.05).
Conclusion: Less than half of the students had sometimes and frequently at other times thinking of suicide. Self-esteem and self-compassion were significantly correlated, and suicidal behavior was significantly affected by students' self-esteem and self-compassion. The supportive resources through academic guidance and psychological counseling units that are staffed and supervised by psychologists, activating student extracurricular activities and sports clubs, will help enhance self-esteem and self-compassion and consequently minimize suicidal behaviors.
ANODE HEEL EFFECT ATTENUATION IN LUMBAR SPINE RADIOGRAPHY: CAN THE USE OF ALUMINIUM FILTERS IMPROVE CLINICAL PRACTICE OF RADIOGRAPHERS?
Authors: RIBEIRO Luís Pedro Vieira , ABRANTES António Fernando Caldeira Lagem , LESYUK Oksana , DORES Rúben , SOUSA Patrick , RODRIGUES Sónia , de ALMEIDA Rui Pedro Pereira , AZEVEDO Kevin AZEVEDO , SOARES Joana , ALEIXO João 
Published: March 2021

Purpose: The aim of this study was to design an aluminium-based filter to reduce the anode heel effect in lumbar spine radiographs. Methods: Initially, lumbar spine examinations were observed in a public imaging department to determine the standard exposure parameters. Then, the characterization of the anode heel effect was made using the Unfors Xi R/F detector and based on the data collected, aluminium filters were designed with a wedge shape, with thicknesses ranging from 0.1 to 4.0 mm. The assessment of the entrance skin dose (ESD) reduction was performed on the anthropomorphic phantom, with and without filters, using the universal dosimeter UNIDOS E equipped with an ionization chamber. Lastly, the image quality assessment was performed with the Pehamed Phantom Digrad A+K and image quality surveys were applied to radiographers and radiologists. Results and Discussion: Uniformity of the beam was achieved, especially with the filter number 2, which presents a significant variation of 9% between cathode and anode side. This filter contributes to ESD reduction of 35% and 36% for AP and lateral projection, respectively. Also, according to the radiographers and radiologists, it improves the image quality of lumbar spine radiography. Conclusion: The use of aluminium filters can be advantageous in the clinical practice of radiographers when carrying out lumbar spine radiographs, since it allows to standardize the anode heel effect, reducing the radiation dose to the patient and without compromising the image quality.
IMPLEMENTING IT GOVERNANCE TO LEVERAGE IS/IT VALUE IN AN ORGANIZATION CASE STUDY MIS DEPARTMENT OF PT. XYZ
Authors: Wongso Fery , Kasman Hendra 
Published: March 2021

The objective In this research are to know what are the indicator of good performance, what are the CSF, KPI & KGI for ?, how do we measure and compare both of them? The Methodology used for this research is based on framework released by IT Governance Institute but it is being modified (minor changes) for a certain purpose. Based on our analysis the average IT Maturity level of fourteen IT process at MIS Department PT. XYZ is 2.83 more higher than the result from ISACA survey among 47 US company only 2.62. The IT management of PT. XYZ should not make their self satisfied with this result, as multinational company they have to aware for improving regarding their IT governance. Our research also provided & equipped set action plan & methodology for management to achieve the better IT Maturity Level. There are some recommendations for the IT management in order to achieve the better namely: 1. IT Maturity Level Management have to perform continuous improvement, especially for some IT process such as DS1 (Define Service Level) the lowest maturity rating, DS4 (Ensure Continuous Services) the second lowest maturity rating, PO9 (Assess Risk) & PO10 (Manage Project) the third lowest maturity rating. 2. Management also have to consider for doing the full step methodology in the next assessment. 3. Management have to consider for develop performance measurement tools, this tools will help management to manage IT resources & process for aligning with the business objective
CARA MENINGKATKAN SIKAP DAN KARAKTERISTIK KEPEMIMPINAN (LEADERSHIP) DALAM BERORGAANISASI BAGI PARA PEMUDA KARANG TARUNA BANYU URIP, SURABAYA
Authors: Anshori Mohamad Yusak , Putra Riyan Sisiawan , Sholikhah Inayatus , Arifin Ravica Ulya 
Published: March 2021

Kegiatan pengabdian kepada masyarakat ini dilaksanakan di Balai RW Banyuurip Surabaya dan peserta kegiatan pengabdian kepada masyarakat ini dari Para pemuda karang taruna Surabaya. Pemuda karang taruna ini kurang lebihg berjumlah 50 orang. Melihat begitu pentingnya sikap leadership bagi para pemuda saat ini menjadi hal yang perlu diimplementasikan pula kepada para karangtaruna Banyuurip agar tercapainya tujuan bersama dengan diadakannya peningkatan kesadaran mengenai kepemimpinan untuk menciptakan organisasi yang efektif bagi para pemuda karangtaruna.
Metode pelaksanaan kegiatan pengabdian kepada masyarakat ini terdiri dari tiga tahap. Pertama tahap pesiapan melalui pra-survei, pembentukan tim, pembuatan proposal, koordinasi tim dengan mitra, dan persiapan bahan untuk kegiatan bahan pengabdian kepada masyarakat. Tahap kedua yaitu tahap pelaksanaan program berupa sosialisai. Sosialisai dilakukan melalui pemaparan materi, tanya jawab dan diskusi. Dan tahap terakhi adalah pelaporan hasil kegiatan pengabdian kepadamasyarakat.
Las fuentes gráficas como único testimonio del patrimonio arquitectónico olvidado. La arquitectura fronteriza del reino de Sevilla en la Baja Edad Media
Authors: Molina Rozalem Juan Francisco , Arévalo Rodríguez Federico , Atanasio Guisado Alberto 
Published: March 2021

<p class="EGA-abstracttext">Durante la primera mitad del siglo XIV, el concejo de Sevilla, apoyado por la monarquía, la nobleza local y empujado por el temor a una nueva invasión norteafricana, se involucra en un programa de construcción defensiva que requirió un gran esfuerzo logístico para los medios disponibles en la época. Este programa consistió en la construcción de una red defensiva, al sur del territorio que controlaba, la llamada "banda morisca", que incluía al menos cuarenta torres defensivas y pequeñas fortificaciones ubicadas en posiciones estratégicas y comunicadas visualmente, cuyo objetivo era neutralizar las razias nazaríes en esta zona fronteriza. De esas torres apenas algunas se mantienen íntegras, la mayoría están en ruina progresiva o han desaparecido. Abandonadas al finalizar la guerra de Granada la documentación existente es muy escasa y en algunos casos se reduce a dibujos, grabados de viajeros y postales fotográficas. El análisis de esa documentación gráfica es una vía adecuada para el conocimiento de ese patrimonio.</p>
Conversando con… Luis Longhi
Authors: Crespo-Fajardo José Luis , Sagbay-Jaramillo Geovanny , Pillacela-Chin Luisa 
Published: March 2021

<p>Luis Longhi Traverso, catedrático de la Universidad Peruana de Ciencias Aplicadas (UPC) y conferencista internacional, nos recibe una tarde de septiembre a través de videollamada. Estamos ante uno de los arquitectos con mayor proyección del Perú. En las últimas décadas su figura ha sido ampliamente reconocida y sus proyectos le han valido importantes galardones, destacando el Hexágono de Oro 2010, la mayor distinción de la arquitectura peruana. Licenciado por la Universidad Ricardo Palma y con estudios de posgrado en la Universidad de Pennsylvania, trabajó en el estudio de Balkrishna Doshi en Amhedabad (India). En Estados Unidos se desempeñó en las oficinas de Adèle Santos, David Slovic, Gruen Associates y Farrington Design Group, entre otras. En 1994 regresó a Perú para crear la firma <em>Longhi Architects</em>, centrada en realizar arquitecturas con un alto grado de sentido artístico.</p><p><em> </em></p><p>Un ejemplo es la casa donde actualmente reside y desde la que nos recibe virtualmente: la Casa Chullpas (afueras de Lima), cuyas estructuras tubulares se relacionan con los restos arqueológicos incas de las chullpas de Sillustani, en Puno, su lugar de nacimiento. El interior de la casa Chullpas está lleno de esculturas, unas propias, las más abstractas, y otras de cariz precolombino. Las maquetas de cartón y madera nos recuerdan su oficio docente, en tanto los carteles anunciadores de representaciones teatrales hablan de la época en que ejerció como escenógrafo. Entre piedras y el gris hormigón pintado de tonos magentas, amarillos y azules, el <em>Inca Longhi</em>, como le llaman sus amigos, ha pasado este tiempo de confinamiento.</p>
Correlation between KRAS, NRAS and BRAF mutations
and tumor localizations in patients with primary
and metastatic colorectal cancer
Authors: Bożyk Aleksandra , Krawczyk Paweł , Reszka Katarzyna , Krukowska Kinga , Kolak Agnieszka , Mańdziuk Sławomir , Wojas-Krawczyk Kamila , Ramlau Rodryg , Milanowski Janusz 
Published: March 2021

IntroductionDetection of abnormalities in the KRAS, NRAS and BRAF genes
is extremely important for proper qualification of colorectal cancer (CRC) patients for therapy with anti-EGFR (epidermal growth factor receptor) monoclonal antibodies. However, data about prevalence of mutations in these
genes, in different localizations of CRC tumors, are limited.Material and methodsWe examined the frequency of mutations in the
KRAS, NRAS and BRAF genes in 500 Caucasian CRC patients (200 women
and 300 men, median age 66 years). DNA was isolated from formalin-fixed,
paraffin-embedded (FFPE) tissues using a Qiagen QIAamp DNA FFPE-kit.
Analysis of mutations was carried out using the KRAS/BRAF, NRAS and BRAF
Mutation Analysis Kit for Real-Time PCR (EntroGen) with the Cobas 480 realtime PCR apparatus (Roche Diagnostics).ResultsKRAS mutations were detected in 190 patients (38%), NRAS mutations in 20 patients (4%), and BRAF mutations in 24 patients (4.8%). There
were no associations between age of CRC patients and frequency of KRAS,
NRAS and BRAF gene mutations. These mutations were significantly more
often diagnosed in women (55.5%) than in men (41%, p < 0.005). Tumors of
the rectum and sigmoideum were the most often observed in both groups
of CRC patients – with and without KRAS, NRAS and BRAF gene mutations.
However, transverse colon, ascending colon and cecum cancers were the
most often affected by mutations.ConclusionsOur study showed that the occurrence of mutations in the
KRAS, NRAS and BRAF genes is not accidental and depends on the location
of CRC tumors.