bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integral and integro-differential equations with an exponential kernel and applications
Authors: Antipov Y A , Mkhitaryan S M 
Published: June 2021

Summary
A convolution integral equation of the first kind and integro-differential equation of the second kind with the kernel $e^{-\gamma |y-\eta|}$ on a finite and semi-infinite interval are analyzed. For the former equation necessary and sufficient conditions for the existence and uniqueness of the solution are obtained, and when the solution exists, a closed-form representation for the solution is derived. On the basis of these results new integral relations for the spheroidal functions and Laguerre polynomials are obtained. The integro-differential equations on a finite and semi-infinite interval are transformed into a vector and scalar Riemann–Hilbert problem, respectively. Both problems are solved in closed-form. An application of these solutions to bending problems of a strip-shaped and a half-plane-shaped plate contacting with an elastic linearly deformable three-dimensional foundation characterized by the Korenev kernel $AK_0(\delta r)$ ($A$ and $\delta$ are parameters, $K_0(\cdot)$ is the modified Bessel function, and $r=\sqrt{(x-\xi)^2+(y-\eta)^2}$) is considered.
Race and Ideology in a Pandemic: White Privilege and Patterns of Risk Perception during COVID-19
Authors: Vargas Nicholas , Mora G Cristina , Gleeson Shannon 
Published: June 2021

AbstractDrawing on a unique survey dataset of Californians collected during the early stages of the COVID-19 pandemic, this article examines how race and ideology shape perceptions of risk. Specifically, we position the pandemic as an “unsettled time” (Swidler 1986) and examine how different racialized groups made sense of the economic and health risks posed during this unprecedented period. We find that even when accounting for economic precarity and potential exposure to COVID-19, as well as for various other measures of social status, racialized minorities felt significantly more threatened by COVID-19 than did whites. Religion and political ideology mediated this relationship to some degree, but the racialized differences were substantial. Indeed, we find that even the most liberal whites reported being significantly less concerned about some COVID-19 risks than the most politically conservative of our Latinx and Black respondents. By linking the literature on race and racial stratification with research on risk and culture, we argue that whiteness facilitates a cognitive insulating effect vis-à-vis COVID-19 risks. We discuss the theoretical implications of our findings and conclude by highlighting the enduring importance of racialization, including various manifestations of white privilege, when assessing the social and cultural realities of crises on the ground.
Strategic Citizenship in China: Birth Tourism and the “American Hukou”
Authors: Folse Brandon 
Published: June 2021

Abstract
The increasing acceptance of dual citizenship globally and the rise of new strategies to acquire “external” citizenship have led to a shift from studying citizenship in the confines of single nation-states to perceiving it as existing in a global hierarchy of “citizenship constellations.” Much of this literature, however, focuses on nations which permit dual citizenship and do not have internal citizenship hierarchies. This article adds to that literature by considering one such external citizenship acquisition method—popularly referred to as “birth tourism.” Based on 23 in-depth interviews and a textual analysis of an online social media group for returnees, I argue that Chinese families use the “external passport” (U.S. citizenship) within the logics of China’s “internal passport” hierarchy (the hukou) to create a unique “citizenship constellation.” U.S. citizenship—understood as the “American hukou”—is more valuable within China’s borders than beyond, as it helps navigate national fertility and education policies. However, maintaining U.S. citizenship in China requires extra labor for parents, particularly mothers. Yet these efforts are still worth it because the acquisition of global citizenship via birth tourism permits families to reap the benefits of global citizenship without damaging their social status, economic security, and family structures.
A genome-wide association study identifies Arabidopsis thaliana genes that contribute to differences in the outcome of infection with two Turnip mosaic potyvirus strains that differ in their evolutionary history and degree of host specialization
Authors: Butković Anamarija , González Rubén , Rivarez Mark Paul Selda , Elena Santiago F 
Published: June 2021

Abstract
Viruses lie in a continuum between generalism and specialism depending on their ability to infect more or less hosts. While generalists are able to successfully infect a wide variety of hosts, specialists are limited to one or a few. Even though generalists seem to gain an advantage due to their wide host range, they usually pay a pleiotropic fitness cost within each host. On the contrary, a specialist has maximal fitness within its own host. A relevant yet poorly explored question is whether viruses differ in the way they interact with their hosts’ gene expression depending on their degree of specialization. Using a genome-wide association study approach, we have identified host genes whose expression depends on whether hosts were infected with more or less specialized viral strains. Four hundred fifty natural accessions of Arabidopsis thaliana were inoculated with Turnip mosaic potyvirus strains with different past evolutionary histories and that shown different degrees of specialization. Three disease-related traits were measured and associated with different sets of host genes for each strain. The genetic architectures of these traits differed among viral strains and, in the case of the more specialized virus, also varied along the duration of infection. While most of the mapped loci were strain specific, one shared locus was mapped for both strains, a disease-resistance TIR-NBS-LRR class protein. Likewise, only putative cysteine-rich receptor-like protein kinases were involved in all three traits. The impact on disease progress of 10 selected genes was validated by studying the infection phenotypes of loss-of-function mutant plants. Nine of these mutants have altered the disease progress and/or symptoms intensity between both strains. Compared to wild-type plants six had an effect on both viral strains, three had an effect only on the more specialized, and two were significant during infection with the less specialized.
Does Local Female Political Representation Empower Women to Run for Higher Office? Evidence from State and National Legislatures in India
Authors: Brown Ryan , Mansour Hani , O’Connell Stephen D 
Published: June 2021

Abstract
Does increasing the number of women in career stages that precede high-level positions affect female representation at the top of the career ladder? State legislature elections narrowly won by female candidates in India are exploited to examine the effect of expanding the pipeline of women in local politics on subsequent female representation and success in national legislature elections. For each additional state legislature election won by a woman, there is a 34 percent increase in the number of female candidates contesting in the subsequent national election, and a 2.6 percentage-point increase in the average vote share won per female candidate. This relationship is driven by new female politicians and not by the progression of female state legislators nor by continued candidacy of previous female candidates for the national legislature.
An Innovative Palatoplasty for Primary Cleft Palate Repair
Authors: Rossell-Perry Percy 
Published: June 2021

Summary:
Many surgical techniques have been developed to restore function in patients with cleft palate. Despite the development of many surgical techniques for primary cleft palate repair there is no standard procedure that ensures palatal function as that in normal children. Furlow’s and intravelar veloplasty are the most common methods for velar repair in patients with cleft palate; however, some limitations have been described by different authors. The objective of this study was to present an innovative method for primary cleft palate repair that addresses the shortcomings of conventional methods. Since 2017, 88 consecutive patients with nonsyndromic unilateral cleft palate have undergone primary anatomical repair of palatal deformity using this technique. This method combines nasal mucosa Z plasty and muscular overlapping with the use of one hemiuvula for uvular repair (unilateral uvuloplasty). The nasal mucosa Z plasty produces velar lengthening by transposition of nasal mucosa and myomucosal flaps. The unilateral uvuloplasty reduces anatomically the velopharyngeal gap and increases the velar length, thus reducing velopharyngeal distance. This innovative palatoplasty, achieves proper anatomical and functional reconstruction of the repaired palate. Only four patients (4.54%) developed mild or severe hypernasality and one patient (1.13%) had postoperative palatal fistula in this group of patients. This innovative technique results in low rates of nondesirable outcomes, improving limitations of conventional methods. Reduced oral mucosa incisions, limited velar muscle dissection, and preservation of the tensor veli palatini anatomy are some of the benefits of this technique.
The Objective Effect of Breast Implant Removal and Capsulectomy on Pulmonary Function
Authors: Wee Corinne E. , Younis Joseph , Boas Samuel , Isbester Kelsey , Smith Arvin , Harvey Donald J. , Patil Nirav , Kumar Anand R. , Feng Lu-Jean 
Published: June 2021

Background:
Breast Implant Illness after aesthetic breast augmentation remains a poorly-defined syndrome. Prior published studies have identified difficulty breathing as a symptom, but definitive improvement in breathing following breast implant removal remains understudied. We hypothesized that patients presenting with breathing symptoms attributed to breast implants would have objective improvement in pulmonary function tests after complete implant/capsule explantation.

Methods:
A retrospective study of all patients who underwent investigation for symptomatic breast implants by a single surgeon over 2 years was conducted. Paired T-tests were used to compare PFTs before and after surgery. Multivariate analyses and linear regression models were used to examine the impact of patient- and implant-related factors, including size and texture on PFT changes.

Results:
Sixty-nine patients met inclusion criteria. Forced vital capacity (mean pre: 3.67 ± 0.61 L versus post: 3.82 ± 0.55 L), forced expiratory volume (2.78 ± 0.44 L versus 2.89 ± 0.39 L), and peak expiratory flow rate (5.91 ± 1.43 L versus 6.56 ± 0.96 L) were significantly improved postoperatively (P = 0.004, 0.01, 0.0001, respectively). Textured implants were associated with a greater improvement in PFTs after their removal (P = 0.009). Implant size and capsular contracture, even when controlled relative to body mass index, were not independent predictors of improvement.

Conclusions:
This study demonstrates that patients presenting with symptomatic breast implants with pulmonary complaints had significant improvement in pulmonary function after complete implant/capsule explantation. Forced vital capacity, forced expiratory volume, and peak expiratory flow rate consistent with a restrictive pattern of ventilation reliably improved in this symptomatic cohort. Textured implants were a significant predictive variable for improvement in pulmonary function.
CLINICAL FEATURES AND OUTCOMES OF INFANTS WITH RETINOPATHY OF PREMATURITY WHO FAIL ANTIVASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY
Authors: Xu Lucy T. , Levine David A. , Hutchinson Amy K. , Rao Prethy , Hubbard George B. 
Published: June 2021

Purpose:
To describe characteristics and outcomes of patients with retinopathy of prematurity who failed intravitreal antivascular endothelial growth factor.

Methods:
A retrospective case series of 211 eyes (112 patients) treated with antivascular endothelial growth factor as initial therapy for retinopathy of prematurity at a single academic institution between 2011 and 2019 and an additional 6 eyes (3 patients) referred to us for management of failed antivascular endothelial growth factor.

Results:
Among the 211 eyes receiving initial treatment at our institution, 17 eyes (11%) failed. Of the 23 total eyes managed by us for failure, 3 eyes (13%) failed after 50-week postmenstrual age. Failure manifested as recurrent plus in 14 eyes (58%), recurrent Stage 3 in 13 eyes (54%) and retinal detachment in 5 eyes (21%). Treatment failures were managed with laser (13 eyes), repeat injection (4 eyes), vitrectomy (2 eyes), or a combination of modalities (4 eyes). Follow-up of ≥6 months was available for 18 of the 23 eyes. The retina was fully attached in 17 eyes, and fixation behavior was present in 10 eyes.

Conclusion:
The most common manifestations of treatment failure were recurrent plus and Stage 3. The failure rate at our institution was 11.0%. A significant proportion of failures occurred after 50-week postmenstrual age. Most failed eyes had favorable anatomical outcomes and over half demonstrated fixation behavior.
Maximal lymph nodal diameter on N stage of nasopharyngeal carcinoma
Authors: Huang Shi-Ting , Qu Song , Li Ling , Chen Kai-Hua , Zhu Xiao-Dong , Pan Xin-Bin 
Published: June 2021

Abstract
To assess the maximal lymph nodal diameter on the 8th edition American Joint Committee on Cancer staging system of nasopharyngeal carcinoma (NPC).
This study extracted NPC patients between 2004 and 2016 in the Surveillance, Epidemiology, and End Results database. Included patients were divided into 3 groups: ≤3 cm, >3–6 cm, and >6 cm based on the maximal lymph nodal diameter. Cumulative survival curves of 5-year overall survival (OS) and cancer-specific survival (CSS) were calculated using the Kaplan-Meier method between the 3 groups.
The 5-year OS (64.0% vs 59.3%, P = .240) and CSS (71.8% vs 67.0%, P = .242) of ≤3 cm and >3–6 cm groups were not different. In contrast, the 5-year OS and CSS were different between >6 cm and ≤3 cm groups, and between >6 cm and >3–6 cm groups. The stratified hazard ratio of OS and CSS was 1.75 (95% confidence interval: 1.25–2.45; P = .001) and 1.77 (95% confidence interval: 1.20–2.60; P = .004) for the >6 cm group in the multivariate regression analysis.
It is reasonable that the maximal lymph nodal diameter with >6 cm is classified as stage N3 of the 8th edition American Joint Committee on Cancer staging system for NPC.
HIV infection and risk of COVID-19 mortality
Authors: Dong Yonghai , Li Zhongjian , Ding Sheng , Liu Shulong , Tang Zhiyuan , Jia Lina , Liu Jiahong , Liu Yun 
Published: June 2021

Abstract

Background:
This meta-analysis aimed to estimate the association of human immunodeficiency virus (HIV) infection and risk of coronavirus disease 2019 (COVID-19) mortality.

Methods:
We systematically retrieved articles published on HIV infection and risk of COVID-19 mortality through PubMed, EMBase, China National Knowledge Infrastructure, WanFang, and Chongqing VIP databases using a predefined search strategy from December 1, 2019 to January 31, 2021. Newcastle–Ottawa Scale (NOS) was used to assess the quality of the included studies. Cochran Q test and I
2 statistics were quantified to measure heterogeneity. Odds ratio (OR) and 95% confidence intervals (CI) were computed and displayed in the form of forest plots. Subgroup analysis was performed to explore the source of heterogeneity. Funnel plot, Begg test, and Egger test were used to assess potential publication bias. Stata software version 11.0 was used to analyze all the statistical data.

Results:
We included 10 studies with 18,122,370 COVID-19 patients, of whom 41,113 were with HIV infection and 18,081,257 were without HIV infection. The pooled overall results suggested that people living with HIV infection had a higher risk of mortality from COVID-19 than those without HIV infection (OR = 1.252, 95% CI 1.027–1.524). Subgroup analysis showed that people living with HIV infection had a higher risk of COVID-19 mortality than those without HIV infection in the United States (OR = 1.520, 95% CI 1.252–1.845) and in South Africa (OR = 1.122, 95% CI 1.032–1.220); however, no significant association was found in the United Kingdom (OR = 0.878, 95% CI 0.657–1.174).

Conclusion:
Patients with HIV infection should be the emphasis population to prevent the risk of mortality during the clinical treatment of COVID-19 patients.
Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like Episodes (MELAS) Syndrome
Authors: Galnares-Olalde Javier A. , López-Hernández Juan C. , Benitez-Alonso Edmar O. , de Montellano David J.D.-O. , May-Mas Raúl N. , Briseño-Godínez María E. , Pérez-Valdez Esther Y. , Pérez-Jovel Enrique , Fernández-Valverde Francisca , León-Manríquez Elizabeth , Vargas-Cañas Edwin S. 
Published: June 2021

Introduction:
Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome, is a multisystemic entity of mitochondrial inheritance. To date, there is no epidemiological information on MELAS syndrome in Mexico.

Case Series:
A retrospective, cross-sectional design was employed to collect and analyze the data. The clinical records of patients with mitochondrial cytopathies in the period ranging from January 2018 to March 2020 were reviewed. Patients who met definitive Yatsuga diagnostic criteria for MELAS syndrome were included to describe frequency, clinical, imaging, histopathologic, and molecular studies. Of 56 patients diagnosed with mitochondrial cytopathy, 6 patients met definitive Yatsuga criterion for MELAS (10.7%). The median age at diagnosis was 34 years (30 to 34 y), 2 females and the median time from onset of symptoms at diagnosis 3.5 years (1 to 10 y). The median of the number of stroke-like episodes before the diagnosis was 3 (range, 2 to 3). The main findings in computed tomography were basal ganglia calcifications (33%), whereas in magnetic resonance imaging were a lactate peak in the spectroscopy sequence in 2 patients. Five patients (84%) had red-ragged fibers and phantom fibers in the Cox stain in the muscle biopsy. Four patients (67%) had presence of 3243A>G mutation in the mitochondrial MT-TL1 gene. One patient died because of status epilepticus.

Conclusions:
MELAS syndrome represents a common diagnostic challenge for clinicians, often delaying definitive diagnosis. It should be suspected in young patients with stroke of undetermined etiology associated with other systemic and neurological features.
Correcting Wide Alar Base and Flare With Combined Sill and Alar Excision in Asian Patients
Authors: Yu Bao-Fu , Li Shu-Qiang , Chen Xiao-Xue , Wei Jiao , Dai Chuan-Chang 
Published: June 2021

Background:
Obvious scar and deformities are commonly observed with incision anterior to the alar-facial groove in alar excision surgery. The authors explored modified sill and alar excision to correct wide alar base and flare synchronously and decreased incident of unacceptable scar and deformities in Asian patients.

Methods:
The authors conducted a retrospective cohort study including 52 consecutive patients undergoing this surgery. Contrary to previous studies, the incision for alar excision was located in the alar-facial groove and was closed by intracutaneous suture. Scars were assessed with visual analog scale and the Stony Brook Scar Evaluation Scale. Ratio of the interalar distance to intercanthal distance, nostril shape, and nostril symmetry was recorded.

Results:
The mean follow-up time was 18 months. Visual analog scale results showed 50 patients (96.2%) reported unnoticeable scar and 2 noticeable but acceptable scar. Stony Brook Scar Evaluation Scale results indicated 49 patients (94.2%) with good scar outcomes and 3 (5.8%) with moderate scar outcomes. The mean ratio of interalar distance to intercanthal distance reduced significantly from preoperative 1.10 to postoperative 1.02. The frequency of horizon-shaped nostrils changed from preoperative 16 cases (30.8%) to postoperative 2 cases (3.8%). The frequency of the pear-shaped (preferred shape) nostrils improved from preoperative 15 cases (28.8%) to postoperative 26 cases (50.0%). The frequency of symmetrical nostril shape improved from preoperative 36 patients (69.2%) to 42 (80.8%). There were no patients with complications like alar deformities, and patients’ dissatisfaction.

Conclusions:
When performing sill and alar excision in Asian patients, the authors recommended a modified approach with the incision for alar excision being placed in the alar-facial groove and closed by intracutaneous suture, which can avoid obvious scar and deformities in Asian patients.
Level of evidence: Level 4.
Alcohol and Drug Use While Cycling Significantly Increases the Likelihood of Facial Fractures
Authors: Sorenson Thomas J. , Rich Matthew D. , Hagstrom Michael , Lamba Abhinav , Barta Ruth J. , Schubert Warren 
Published: June 2021

Purpose:
Substance use, including alcohol and drugs, has been found to amplify the risks associated with cycling. Our purpose was to determine the relationship between alcohol or drug use and facial injuries in a nationwide population of patients experiencing cycling trauma.

Methods:
The authors report a cross-sectional study of patients reported to the National Electronic Injury Surveillance System from January 1, 2019 to December 31, 2019, in the United States. Patients were included in our study if they were evaluated in the emergency department for a cycling-related injury. Primary outcome was facial injury.

Results:
There were a total of 6499 adult patients who experience an injury after cycling trauma reported by the National Electronic Injury Surveillance System-participating emergency departments during the study period. A total of 553 (553/6499; 8.5%) patients had a facial injury and 82 patients with facial injuries had alcohol/drug use recorded (82/553; 14.8%). The proportion of males with facial injuries was higher in the alcohol/drug group than the no alcohol/drug group (86.6% versus 76.4%, respectively; P = 0.04). Injured cyclists in the alcohol/drug group experienced greater odds of sustaining a facial injury (odds ratio: 2.21, 95% confidence interval: 1.71–2.84, P < 0.0001) and a facial fracture (odds ratio: 2.75, 95% confidence interval: 1.83–4.13, P < 0.0001) than injured cyclists in the no alcohol/drug group.

Conclusions:
Substance use while cycling is not safe and significantly increases the likelihood of a facial injury and of facial fractures. This prevalence of injuries would suggest that cycling under the influence should always be illegal, and the law strictly enforced.