bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cross-disciplinary issues in international marketing: a systematic literature review on international marketing and ethical issues
Authors: Chatterjee Sheshadri , Chaudhuri Sumana , Sakka Georgia , Apoorva  
Published: April 2021

PurposeThe purpose of this paper is to discuss the evolution of the cross-disciplinary area of ethics and international marketing and to highlight the current and future scope of research in this area.Design/methodology/approachThe authors conducted a systematic literature review (SLR) of research papers from reputed journals which publish articles in this cross-disciplinary subject area. This paper especially investigates the perception, issues, concepts and theories used in ethics and international marketing. Scopus and Web of Science databases were primarily used to select the articles.FindingsThe paper highlights the importance of cross-disciplinary research in the areas of ethics and international marketing. The study also shows different kinds of research work published in this area between 1994 and 2020. Also, the study shows that the maximum research has been conducted in the USA and the UK. Finally, the paper also highlights the major theories that different authors have used in this interdisciplinary area.Research limitations/implicationsThe paper does not discuss other complex areas of cross-disciplinary international marketing other than ethics and international marketing. The paper omits the literature from books, stand-alone nonindexed journals, etc. Also, the paper has only used the Web of Science and Scopus databases.Practical implicationsThe study argues the importance of ethics in international marketing. The study also provides inputs to the international marketers so that they can successfully address the complex challenges in the cross-disciplinary area of ethics and international marketing. The study also helps marketers to rethink their approaches on international marketing ethics.Originality/valueThis may be one of the few studies in the cross-disciplinary area of ethics and international marketing. This paper can open avenues and influence other researchers to study the cross-disciplinary areas of marketing.
Employees' task performance and propensity to take charge: the role of LMX and leader's task orientation
Authors: Ahmed Ishfaq , Afzal Rabia , Abdul Rasid Siti Zaleha 
Published: April 2021

PurposeRecent literature has focused on the outcomes associated with employee performance, but how and when it leads to work-related outcomes further is an area that has not gained due attention. Against this backdrop, this study entails investigating the effects of employee performance on their taking-charge behavior through the mediation of leader–member exchange (LMX) and the leader's task-oriented behavior's moderating role.Design/methodology/approachUsing a questionnaire-based survey design, the study is based on a sample of 304 employees of pharmaceutical companies' sales departments. The two-stage lag approach has been used for data collection, where leader–follower dyads participated in the study.FindingsThe study's findings reveal that better-performing employees are considered in-group members by their leaders, and the presence of high LMX makes employees reciprocate by adopting charge behavior. Furthermore, a leader's task-oriented behavior fosters the performance – LMX and performance – taking charge relationship mediated through LMX, a moderated mediation mechanism exists.Originality/valueThe study offers a novel explanation by considering employee performance as a predictor instead of an outcome variable. Furthermore, recent literature has considered adverse outcomes of performance, while this study considers the positive aspects of employee performance (i.e. LMX and charge behavior). It also offers the role of both employee- and leader-specific factors in determining the LMX relationship.
Governmental customer concentration and audit pricing
Authors: Chen Hanmei , Jia Weishi , Li Shuo , Liu Zenghui 
Published: April 2021

Purpose
The purpose of this paper is to examine how the concentration of a specific customer type – governmental customer, affects the pricing of audit services in the USA.

Design/methodology/approach
This paper applies a standard audit pricing model by regressing audit fees on governmental customer concentration and other common determinants of audit fees. This paper also adopts an instrumental variable approach and performs propensity-score matched sample analyzes to mitigate the potential endogeneity problem.

Findings
Using data from major customer disclosures of US publicly listed firms from 2000 to 2014, this paper finds that governmental customer concentration is positively associated with audit fees, suggesting that a higher level of governmental customer concentration increases a firm’s audit risks and audit effort. In addition, this paper performs cross-sectional analyzes and show that the association between governmental customer concentration and audit fees is more pronounced for firms with weak internal governance, weak external monitoring and high financial risks.

Originality/value
This paper furthers the understanding of the interactive relationships in supply chain systems and adds new evidence to the literature on customer concentration. Prior studies on customer concentration typically treat all customer types in a uniform manner. To the knowledge, this is the first study that separates governmental customers from other types of customers in an audit pricing setting. The findings highlight the importance of examining governmental customer concentration when assessing a firm’s audit risks and audit fees.
A study on capital budgeting practices of some selected companies in Bangladesh
Authors: Mollah Md. Anhar Sharif , Rouf Md. Abdur , Rana S.M. Sohel 
Published: April 2021

Purpose
The purpose of this paper is to investigate the current capital budgeting practices in Bangladeshi listed companies and provide a normative framework (guidelines) for practitioners.

Design/methodology/approach
Data were collected with a structured questionnaire survey taking from the chief financial officers (CFOs) of companies listed in the Dhaka Stock Exchange in Bangladesh. Garnered data were then analyzed using descriptive and inferential statistical techniques.

Findings
The results found that net present value was the most prevalent capital budgeting method, followed closely by internal rate of return and payback period. Similarly, the weighted average cost of capital was found to be the widely used method for calculating cost of capital. Further, results also revealed that CFOs adjust their risk factor using discount rate.

Originality/value
The findings of this study might help the firms, policymakers and practitioners to take a wise decision while evaluating investment projects. Additionally, this study’s findings enrich the existing body of knowledge in the field of capital budgeting practices by providing more reliable and comprehensive analysis taking samples from a developing economy.
Managerial adaptability and business strategic change in age of COVID-19
Authors: Mercedes D'Alizza , Burrell Darrell Norman 
Published: April 2021

Purpose
The purpose of this paper is to investigate the consequential impact of COVID-19 on mental health organizations. Via the context organizational development (OD) action research of an organizational case analysis, this paper offers recommendations to mental health organizations on an approach to help recover from the financial losses caused by COVID-19 restrictions and to also help ensure that mental health specialists are provided with sufficient support so they may continue to provide meaningful service to clients in need of therapeutic care and assistance.

Design/methodology/approach
The approach is an action research case study that uses an OD framework and a content analysis of the current literature.

Findings
The real-world case study uses an action research OD intervention to provide tools and recommendations that other similar organizations might be able to use to respond to COVID-19. The findings implicate practices and approaches that organizations can use to adapt to business and marketplace disruption of COVID-19.

Originality/value
COVID-19 is an emerging issue, as a result any research and development in this area is of significant value to researchers and professionals.
Antimicrobial uv curable wood coatings based on citric acid
Authors: Dixit Anand , Wazarkar Kunal , Sabnis Anagha S. 
Published: April 2021

Purpose
Epoxy acrylate which is commercially utilized for UV curable coatings although has excellent adhesion, flexibility, hardness and chemical resistance, they lack in antimicrobial properties. Citric acid (CA) is economical as well as a bio-based compound which possess an antimicrobial activity. So, the purpose of this research investigation is the preparation of CA-based oligomer which can be further incorporated with epoxy acrylate and tri (propylene glycol) Diacrylate (TPGDA) to form uv curable coating and the study of its antimicrobial property.

Design/methodology/approach
A UV-curable unsaturated oligomer (CUV) was synthesized from CA and glycidyl methacrylate (GMA). The chemical structure of CUV was confirmed by FTIR, 1H NMR, GPC, hydroxyl value, acid value and iodine value. Further, CUV was assimilated as an antimicrobial as well as crosslinking agent to copolymerize with epoxy acrylate oligomer and a series of UV-cured antimicrobial coatings were concocted by employing UV-curing machine. The consequence of varying the fraction of CUV on the mechanical, chemical, thermal and antimicrobial properties of UV-cured wood coatings was explored.

Findings
Results exhibited good mechanical, chemical and thermal properties. In addition, it was perceived that the zone of inhibition against S. aureus got enlarged with increasing content of CUV in the coating formulation.

Originality/value
The synthesized bio-based CUV reveals an extensive potential to ameliorate the antimicrobial properties of UV-curable coatings.
Chrysophyllum marginatum (Sapotaceae): Generalist pollination and cryptic gynomonoecious
Authors: Sigrist Maria Rosângela , Leme Flávia M. , Fabiano Vitória S. , Pinheiro Fernanda P. , dos Santos Ferreira Bruno H. , Nakamura Samanda S. , da Silva Sara O. 
Published: April 2021

AbstractChrysophyllum (Chrysophylloideae, Chrysophylleae) is the second largest genus in the Sapotaceae. Studies of pollination ecology in this genus are non‐existent, although there are records of entomophily for this family. Considering the lack of detailed studies on pollination ecology and sexual systems in Chrysophyllum species, we investigate the floral morphology and biology and floral visitors of Chrysophyllum marginatum to verify which sexual system is present in the studied population and whether flowers of this species are visited and pollinated by different insect groups. The population of C. marginatum has weak and cryptic gynomonoecy because the plants produce a low percentage of functionally pistillate flowers (4.2%) and these flowers appear to be perfect flowers (hermaphrode). Flowers of C. marginatum are phenotypically, ecologically and functionally generalist because: (a) they are actinomorphic, open and not restrictive in terms of access to floral resources; (b) they are visited by 26 species of insects that are potential pollinators; and (c) among these species several groups can be effective pollinators, mainly bees and flies, according to the most effective pollinator principle. We consider bees and flies to be the main pollinator group of C. marginatum, due to their high visitation rate, richness and intrafloral visiting behavior, and because they especially forage among plant individuals and are able to promote xenogamy. Nectaries were found in the ovary base and osmophores in the petal margins, as floral attractants. For Chrysophyllum, this is the first record of gynomonoecy and for the family this is considered the second record. Chrysophyllum marginatum has generalist and entomophilous pollination, as recorded in other Sapotaceae Neotropical species.
Impact of analysis technique on our understanding of the natural history of labour: a simulation study
Authors: de Vries BS , Mcdonald S , Joseph FA , Morton R , Hyett JA , Phipps H , McGeechan K 
Published: April 2021

ObjectiveTo evaluate the discrepancy between historical and more recent descriptions of the first stage of labour by testing whether the statistical techniques used recently (repeated‐measures polynomial and interval‐censored regression) were appropriate for detection of periods of rapid acceleration of cervical dilatation as might occur at the time of transition from a latent to an active phase of labour.Design and settingA simulation study using regression techniques.SampleWe created a simulated data set for 500 000 labours with clearly defined latent and active phases using the parameters described by Friedman. Additionally, we created a data set comprising 500 000 labours with a progressively increasing rate of cervical dilatation.MethodsRepeated‐measures polynomial regression was used to create summary labour curves based on simulated cervical examinations. Interval‐censored regression was used to create centimetre‐by‐centimetre estimates of rates of cervical dilatation and their 95th centiles.Main outcome measuresLabour summary curves and rates of cervical dilatation.ResultsRepeated‐measures polynomial regression did not detect the rapid acceleration in cervical dilatation (i.e. acceleration phase) and overestimated lengths of labour, especially at smaller cervical dilatations. There was a two‐fold overestimation in the mean rate of cervical dilatation from 4 to 6 cm. Interval‐censored regression overestimated median transit times, at 4‐ to 5‐cm cervical dilatation or when cervical examinations occurred less frequently than 0.5‐ to 1.5‐hourly.ConclusionRepeated‐measures polynomial regression and interval‐censored regression should not be routinely used to define labour progress because they do not accurately reflect the underlying data.Tweetable abstractRepeated‐measures polynomial and interval‐censored regression techniques are not appropriate to model first stage of labour.
Paediatric patients report lower health‐related quality of life in daily clinical practice compared to new normative PedsQLTM data
Authors: van Muilekom Maud M. , Luijten Michiel A. J. , van Oers Hedy A. , Conijn Thirsa , Maurice‐Stam Heleen , van Goudoever Johannes B. , Grootenhuis Martha A. , Haverman Lotte ,   the KLIK collaborator group
Published: April 2021

AbstractAimTo compare Health‐Related Quality of Life (HRQOL) of paediatric patients with newly collected HRQOL data of the general Dutch population, explore responses to individual items and investigate variables associated with HRQOL.MethodsChildren (8–12y) and adolescents (13–17y) from the general population (N = 966) and from a paediatric population (N = 1209) completed the Pediatric Quality of Life Inventory (PedsQLTM) online via the KLIK Patient‐Reported Outcome Measures portal. PedsQLTM scale scores were compared between groups with independent t tests, by age group and gender. Responses to PedsQLTM items were explored using descriptive analyses. Linear regression analyses were performed to determine which variables were associated with HRQOL.ResultsPaediatric patients reported worse HRQOL than the general population on all PedsQLTM scales (p ≤ .001, d = 0.20–1.03), except social functioning, and a high proportion reported problems on PedsQLTM items, for example, ‘I have trouble sleeping’. Younger age, female gender and school absence were negatively associated with HRQOL (β = −0.37–0.10, p ≤ .008).ConclusionPaediatric patients reported lower HRQOL than the general population, and school absence, female gender and younger age were associated with lower HRQOL. The results underline the importance to structurally monitor paediatric patients’ HRQOL in clinical practice to detect problems and offer the right help on time.
Identification of CXCL12‐abundant reticular cells in human adult bone marrow
Authors: Aoki Kazunari , Kurashige Masako , Ichii Michiko , Higaki Kei , Sugiyama Tatsuki , Kaito Takashi , Ando Wataru , Sugano Nobuhiko , Sakai Takashi , Shibayama Hirohiko ,   HANDAI Clinical Blood Club, Takaori‐Kondo Akifumi , Morii Eiichi , Kanakura Yuzuru , Nagasawa Takashi 
Published: April 2021

SummaryA population of mesenchymal stem cells, termed CXC chemokine ligand (CXCL)12‐abundant reticular (CAR) cells or leptin receptor‐expressing cells, are the major cellular component of niches for haematopoietic stem cells (HSCs) in murine bone marrow. CAR cells are characterized by several salient features, including much higher expression of CXCL12, stem cell factor (SCF), forkhead box C1 (FOXC1) and early B‐cell factor 3 (EBF3), which are essential for HSC maintenance, than other cells. However, the human counterpart of CAR cells has not been fully described. Here, we show the presence of cells expressing much higher CXCL12 than other cells in human adult bone marrow using a flow cytometry‐based in situ technique that enables high‐throughput detection of mRNA at single‐cell resolution. Most CXCL12hi cells expressed high levels of SCF, FOXC1 and EBF3 and had the potential to differentiate into adipocytes and osteoblasts. Histologically, the nuclei of CXCL12hi cells were identified and quantified by EBF3 expression in fixed marrow sections. CXCL12hi cells sorted from residual bone marrow aspirates of chronic myeloid leukaemia patients expressed reduced levels of CXCL12, SCF, FOXC1 and EBF3 in correlation with increased leukaemic burden. Together, we identified the human counterpart of CAR cells, enabling the evaluation of their alterations in various haematological disorders by flow cytometric and histological analyses.
Second allogeneic haematopoietic cell transplantation using HLA‐matched unrelated versus T‐cell replete haploidentical donor and survival in relapsed acute myeloid leukaemia
Authors: Kharfan‐Dabaja Mohamed A. , Labopin Myriam , Brissot Eolia , Kroger Nicolaus , Finke Jürgen , Ciceri Fabio , Deconinck Eric , Blaise Didier , Chevallier Patrice , Gramatzki Martin , Ganser Arnold , Stelljes Matthias , Edinger Matthias , Savani Bipin , Ruggeri Annalisa , Sanz Jaime , Nagler Arnon , Mohty Mohamad 
Published: April 2021

SummaryOptimal donor choice for a second allogeneic haematopoietic cell transplant (allo‐HCT) in relapsed acute myeloid leukaemia (AML) remains unknown. We compared overall survival (OS) using registry data from the Acute Leukemia Working Party (ALWP) of the European Society for Blood and Marrow Transplantation (EBMT) involving 455 adults who received a second allo‐HCT from a human leucocyte antigen (HLA)‐matched unrelated (MUD) (n = 320) or a haploidentical (n = 135) donor. Eligibility criteria required adults aged ≥18 years who received a second allo‐HCT for treating AML relapse between 2005 and 2019. The primary end‐point was OS. There was no statistically significant difference in the median (interquartile range) age between the groups, MUD 46 (35–58) versus haploidentical 44 (33–53) years (P = 0·07). The median OS was not different between the MUD and the haploidentical groups (10 vs. 11 months, P = 0·57). Similarly, the 2‐year OS was 31% for the MUD and 29% for the haploidentical donor groups. The OS was worse if the procedure was performed with active AML [hazard ratio (HR) 1·42, 95% confidence interval (CI) 1·07–1·89; P = 0·02]. Conversely, a longer time from first allo‐HCT to relapse (>13·2 months) was associated with better OS (HR 0·50, 95% CI 0·37–0·69; P < 0·0001). The results of the present analysis limit the ability to recommend one donor type over another when considering a second allo‐HCT for relapsed AML. Our findings highlight that best OS is achieved when receiving the second allo‐HCT in complete remission.
LINC01123 enhances osteosarcoma cell growth by activating the Hedgehog pathway via the miR‐516b‐5p/Gli1 axis
Authors: Pan Xiaohui , Tan Jingxue , Tao Tao , Zhang Xiuwen , Weng Yiping , Weng Xiaokun , Xu Jingwen , Li Haibo , Jiang Yuqing , Zhou Dong , Shen Yifei 
Published: April 2021

AbstractThe lncRNA LINC01123 has been reported to act as an oncogene in many human cancers. Nevertheless, the function and underlying mechanism of LINC01123 in osteosarcoma (OS) remain unclear. This study aimed to explore the roles and mechanisms of LINC01123 in OS progression. In this study, the expression of LINC01123 was significantly upregulated in OS cell lines than in a human osteoblast cell line. Furthermore, in vitro and in vivo experiments confirmed that knockdown of LINC01123 suppressed cell progression. Mechanistically, LINC01123 acted as a competing endogenous RNA by sponging miR‐516b‐5p, thus, increasing Gli1 expression by directly targeting its 3ʹUTR. Taken together, LINC01123 enhances OS proliferation and metastasis via the miR‐516b‐5p/Gli1 axis. Therefore, LINC01123 may be a potential therapeutic target for OS treatment.
Glycoconjugates, hypothetical proteins, and post‐translational modification: Importance in host–pathogen interaction and antitubercular intervention development
Authors: Arega Aregitu Mekuriaw , Mahapatra Rajani Kanta 
Published: April 2021

AbstractWith the emergence of multidrug‐resistant bacteria, insufficiency of the established chemotherapy, and the existing vaccine BCG, tuberculosis (TB) subsists as the chief cause of death in different parts of the world. Thus, identification of novel target proteins is urgently required to develop more effective TB interventions. However, the novel vaccine and drug target knowledge based on the essentiality of the pathogen cell envelope components such as glycoconjugates, glycans, and the peptidoglycan layer of the lipid‐rich capsule are limited. Furthermore, most of the genes encoding proteins are characterized as hypothetical and functionally unknown. Correspondingly, some researchers have shown that the lipid and sugar components of the envelope glycoconjugates are largely in charge of TB pathogenesis and encounter many drugs and vaccines. Therefore, in this review we provide an insight into a comprehensive study concerning the importance of cell envelope glycoconjugates and hypothetical proteins, the impact of post‐translational modification, and the bioinformatics‐based implications for better antitubercular intervention development.