bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effect of Health Insurance Coverage on Homeownership and Housing Prices: Evidence from the Medicaid Expansion
Authors: Kuroki Masanori , Liu Xiangbo 
Published: January 2021

ObjectiveHomeownership as a way of wealth accumulation is important for low‐income people and the U.S. government has implemented policy to encourage homeownership among low‐income people. This article investigates the effects of health insurance coverage among low‐income people on homeownership and house prices.MethodsTo estimate the causal effects of health insurance coverage, we exploit the Medicaid expansion provisions of the Affordable Care Act as a source of exogenous variation in health insurance coverage and use it as an instrumental variable.ResultsUsing county‐level data from 2010 to 2018, this study finds that an increase in health insurance coverage among low‐income people results in an increase in homeownership rates and housing prices for bottom‐tier houses, and the results are robust.ConclusionOur study provides new evidence in supporting that higher shares of population with health insurance could increase both homeownership and house prices.
Does Disgust Drive Religious Freedom Attitudes? Experimental Results About the Context of Service Refusal Opinion
Authors: Djupe Paul A. , Lewis Andrew R. , Sokhey Anand E. , Burge Ryan P. 
Published: January 2021

ObjectiveWhat factors shape public support for service refusals carried out in the name of the free exercise of religion? Existing analyses treat the businesses refusing to serve LGBT citizens as fungible. We hypothesize that the religious context does not matter and that reactions are consistent with the role of socialized disgust.MethodsWe engage the same experimental design in two 2019 samples, one of 800 Colorado adult residents and one of 1,010 Protestants. The 1 × 2 × 2 design enables a contrast between a control, conditions that vary the business between a florist and photographer, and conditions that vary the religious nature of the event.ResultsThe results suggest that the religious nature of the context is immaterial and that reactions generally conform with the role of disgust, especially for those socialized to feel it—high attending evangelicals.ConclusionWe affirm the importance of the context of service delivery for religious freedom attitudes and discuss the role of religion.
A phylogeny of the subfamilyThiotrichinae(Lepidoptera:Gelechiidae) with a revision of the generic classification based on molecular and morphological analyses
Authors: Lee Ga‐Eun , Han Taeman , Park Haechul , Qi Mujie , Li Houhun 
Published: January 2021

AbstractThiotrichinae are a subfamily of Gelechiidae with approximately 180 described species in five genera:CalliproraMeyrick,MacrenchesMeyrick,PalumbinaRondani,PolyhymnoChambers andThiotrichaMeyrick. The subfamily was established based on two species in a recent molecular phylogenetic study of Gelechiidae, but the monophyly of each genus and the phylogenetic relationships among the genera have not been tested. To address these questions, we performed the first phylogenetic analyses based on seven molecular markers (COI, EF‐1α, GAPDH, RpS5, CAD, Wg and MDH) and 95 morphological characters for 47 ingroup and 3 outgroup taxa. Each dataset was analysed separately and together using maximum likelihood, Bayesian inference and maximum parsimony methods. The maximum likelihood and Bayesian analyses produced nearly identical tree topologies for ingroup relationships, but the parsimony analysis yielded different results for some lineages. In all our analyses, Thiotrichinae formed a strongly supported monophyletic group with two other gelechiid genera,CnaphostolaMeyrick (Gelechiinae) andSemnostomaMeyrick (Apatetrinae). The genusMacrencheswas recognized as the sister‐group to all other species in this clade.Polyhymno + Calliprorawere found to be sister to all remaining ingroup taxa. The species‐rich groupThiotrichawas non‐monophyletic, and it clustered withPalumbina,CnaphostolaandSemnostoma. The type species ofThiotrichawas included in a monophyletic clade with a majority of congeneric species in the parsimony analyses, but the clade was divided into two groups in the model‐based results. The generic placement of two speciesThiotricha dissobolaMeyrick andT. pyrphoraMeyrick was not confirmed in this study and they were placed asincertae sedis. The monophyly ofPalumbinawas strongly supported by both molecular data and morphological evidence. Based on genetic and morphological affinities and examination of the type specimens, four genera are synonymized withThiotricha:BlastovalvaJansesyn.n.,Cnaphostolasyn.n.,HierangelaMeyricksyn.n.andSemnostomasyn.n.We propose two new genera for newly recognized two sub‐clades:Pulchralagen.n.andTenupalpagen.n., and 15 new combinations are made:Thiotricha adamantina(Meyrick)comb.n.,T. exalbida(Omelko & Omelko)comb.n.,Tenupalpa angustella(Omelko)comb.n.,T. biformis(Omelko)comb.n.,T. flavitermina(Kyaw, Yagi & Hirowatari)comb.n.,T. glenias(Meyrick)comb.n.,T. nephodesma(Meyrick)comb.n.,T. venustalis(Omelko)comb.n.,Pulchrala clidias(Meyrick)comb.n.,P. chujaensis(Park)comb.n.,P. elaeocarpiella(Kyaw, Yagi & Hirowatari)comb.n.,P. epiclista(Meyrick)comb.n.,P. melanacma(Bradley)comb.n.,P. panglycera(Turner)comb.n., andP. saulotis(Meyrick)comb.n.Revised generic concepts are provided in the study.This published work has been registered on ZooBank,http://zoobank.org/urn:lsid:zoobank.org:pub:0E3C0EB5‐503C‐4ADC‐BE87‐A203230DE6CB.
Risk factors and clinical outcomes of tuberculosis among kidney transplant recipients in high endemic country
Authors: Thitisuriyarax Saranya , Vanichanan Jakapat , Udomkarnjananun Suwasin , Townamchai Natavudh , Jutivorakool Kamonwan 
Published: January 2021

AbstractBackgroundTuberculosis (TB) is considered as a challenge issue in solid organ transplant recipients because of high morbidity and mortality. Active TB after transplant mostly occurs from reactivation of latent infection. Understanding risk factors and clinical information of TB may provide an appropriate prevention and treatment strategies in this specific patient population, however data from high endemic area is scarce.MethodsA matched single‐center, case‐control study was conducted in our institute. Cases were defined as newly diagnosed confirmed or clinical active TB in patients who underwent kidney transplant (KT) between April 1992 and October 2018. For each case, 5 controls were matched by age and sex. Risk factor associated with TB was determined using univariate and multivariate conditional logistic regression.ResultsBetween study period, KT was performed in 787 patients. Twenty‐seven patients (3.43%) were diagnosed with active TB including 20 confirmed and 7 clinical diagnosed cases. The global incidence of TB in our population was 315 cases per 100 000 patients per year. Among 27 cases, pulmonary involvement was the most common (48.1%) followed by disseminated (18.5%), extrapulmonary (14.8%), pleura (11.1%) and pleuropulmonary (7.4%) TB. Allograft rejection was significantly associated with active TB (P < .001). The median onset duration of infection was 17 months (IQR, 4‐59 months) after KT. Twenty‐four (88.9%) patients received rifampicin containing regimen for treatment with median duration of 10 months (IQR, 6‐12 months). All patients were cured after complete treatment, however those with TB remained having unfavorable outcomes including higher all‐cause mortality and graft loss.ConclusionsIncidence rate of TB in KT recipients is higher than normal population. Allograft rejection was identified as a significant risk factor. Increase unfavorable outcomes including graft loss and mortality were also observed among patients with TB.
Flourishing in water: the early evolution and diversification of plant receptor‐like kinases
Authors: Gong Zhen , Han Guan‐Zhu 
Published: January 2021

SUMMARYReceptor‐like kinases (RLKs) play significant roles in mediating innate immunity and development of plants. The evolution of plant RLKs has been characterized by extensive variation in copy numbers and domain configurations. However, much remains unknown about the origin, evolution, and early diversification of plant RLKs. Here, we perform phylogenomic analyses of RLKs across plants (Archaeplastida), including embryophytes, charophytes, chlorophytes, prasinodermophytes, glaucophytes, and rhodophytes. We identify the presence of RLKs in all the streptophytes (land plants and charophytes), nine out of 18 chlorophytes, one prasinodermophyte, and one glaucophyte, but not in rhodophytes. Interestingly, the copy number of RLKs increased drastically in streptophytes after the split of the clade of Mesostigmatophyceae and Chlorokybophyceae and other streptophytes. Moreover, phylogenetic analyses suggest RLKs from charophytes form diverse distinct clusters, and are dispersed along the diversity of land plant RLKs, indicating that RLKs have extensively diversified in charophytes and charophyte RLKs seeded the major diversity of land plant RLKs. We identify at least 81 and 76 different kinase‐associated domains for charophyte and land plant RLKs, 23 of which are shared, suggesting that RLKs might have evolved in a modular fashion through frequent domain gains or losses. We also detect signatures of positive selection for many charophyte RLK groups, indicating potential functions in host–microbe interaction. Taken together, our findings provide significant insights into the early evolution and diversification of plant RLKs and the ancient evolution of plant–microbe symbiosis.
A prospective observational study of the incidence, natural history, and risk factors for intravenous immunoglobulin‐mediated hemolysis
Authors: Pendergrast Jacob , Armali Chantal , Callum Jeannie , Cserti‐Gazdewich Christine , Jiwajee Aziz , Lieberman Lani , Lau Wendy , Lin Yulia , Parmar Nagina , Pavenski Katerina , Riden Lorna Sampson , Shehata Nadine , Willie‐Ramharack Kezia , Tomlinson George , Tong Tik Nga , Binnington Beth , Branch Donald R. ,   The QUEST Research Program
Published: January 2021

AbstractBackgroundIntravenous Immune Globulin (IVIG) is used to treat numerous immune‐mediated and inflammatory conditions. There is growing awareness of hemolysis, occasionally severe, as a side‐effect of this therapy. While most cases are associated with anti‐A and/or anti‐B isoagglutinins, the frequency and mechanism of hemolysis remain poorly characterized.Study Design and MethodsA prospective observational study was conducted to determine incidence, natural history and risk factors for IVIG‐mediated hemolysis. A total of 99 infusions of high‐dose IVIG (2 g/kg or higher) administered to 78 non‐group O patients were monitored and graded according to Canadian IVIG Hemolysis Pharmacovigilance Group. Serum ferritin and C3/C4 levels were monitored as indicators of macrophage activation and complement consumption, respectively. Supplementary investigations included assessment for ABO zygosity, Secretor status, FcR polymorphisms, eluate IgG subclass, monocyte monolayer assay, and a panel of cytokines.ResultsHemolysis was observed in 32 of 99 (32%) of infusions, with 19 of 99 (19%) grade 2 or higher. Hemolysis was only apparent 5‐10 days after a completed IVIG infusion in 84% of cases and was associated with increases in serum ferritin without complement‐consumption. In univariate analysis, increased risk was observed in group AB patients, first‐time IVIG recipients, those not taking immuosuppressive medications, or patients treated with a specific IVIG brand; however, in multivariate analysis, product association was no longer observed. No other patient‐ or practice‐related risk factors were identified.ConclusionIVIG‐mediated hemolysis is common and frequently severe. Monitoring for 5‐10 days following an infusion should be considered in non‐O patients receiving high‐dose IVIG with known risk factors.
Veterinary Cooperative Oncology Group—Common Terminology Criteria for Adverse Events (VCOG‐CTCAE v2) following investigational therapy in dogs and cats
Authors: LeBlanc Amy K. , Atherton Matthew , Bentley R. Timothy , Boudreau C. Elizabeth , Burton Jenna H. , Curran Kaitlin M. , Dow Steven , Giuffrida Michelle A. , Kellihan Heidi B. , Mason Nicola J. , Oblak Michelle , Selmic Laura E. , Selting Kimberly A. , Singh Ameet , Tjostheim Sonja , Vail David M. , Weishaar Kristen M. , Berger Erika P. , Rossmeisl John H. , Mazcko Christina 
Published: January 2021

AbstractThe updated VCOG‐CTCAE v2 guidelines contain several important updates and additions since the last update (v1.1) was released in 2011 and published within Veterinary and Comparative Oncology in 2016. As the Veterinary Cooperative Oncology Group (VCOG) is no longer an active entity, the original authors and contributors to the VCOG‐CTCAE v1.0 and v1.1 were consulted for input, and additional co‐authors sought for expansion and refinement of the adverse event (AE) categories. VCOG‐CTCAE v2 includes expanded neurology, cardiac and immunologic AE sections, and the addition of procedural‐specific AEs. It is our intent that, through inclusion of additional authors from ACVIM subspecialties and the American College of Veterinary Surgery, that we can more comprehensively capture AEs that are observed during clinical studies conducted across a variety of disease states, clinical scenarios, and body systems. It is also our intent that these updated veterinary CTCAE guidelines will offer improved application and ease of use within veterinary practice in general, as well as within clinical trials that assess new therapeutic strategies for animals with a variety of diseases. Throughout the revision process, we strived to ensure the grading structure for each AE category was reflective of the decision‐making process applied to determination of dose‐limiting events. As phase I trial decisions are based on these criteria and ultimately determine the maximally tolerated dose, there is impact on standard dosing recommendations for any new drug registration or application. This document should be updated regularly to reflect ongoing application to clinical studies carried out in veterinary patients.
Risk of seropositivity to Coxiella burnetii in humans living in areas with endemically infected cattle: No way for specific prevention
Authors: Beaudeau Francois , Pouquet Marie , Guatteo Raphaël , Bareille Nathalie , Moret Leïla 
Published: January 2021

AbstractQ fever, a zoonotic disease caused by Coxiella burnetii, is endemic among cattle in Western France. However, studies assessing the risk of human infection in such areas are lacking to date, while they may provide information about key specific preventive actions which could be advised to the human populations living with or close to cattle. Therefore, we conducted a cross‐sectional study in two departments of Western France during the 2017/18 winter in order to explore possible risk factors for seropositivity among two distinct populations, i) an occupational risk group, that is, the cattle farmers, and ii) the general adult population (approached by blood donors). Sera were collected in 176 cattle farmers and 347 blood donors respectively, and tested for phase I and II antibodies using an indirect immunofluorescence antibody assay. Each participant was asked to fill in a questionnaire containing socio‐demographic characteristics, occupational and non‐occupational risk exposure. Identified risk factors were: in the general population, working in contact with ruminants, comparatively to any other activity (OR = 4.41; 95% CI: [1.59–6.55]); among farmers, managing an itself infected cattle herd (OR = 3.20; 95% CI: [1.59–6.55]). No other controllable risk factor (lifestyle, outdoor activities, proximity to pets and livestock animals, occupational practices) was here evidenced. In areas with endemically infected cattle, human exposure to Coxiella burnetii is to some extent unavoidable. This strengthens the need for physicians' awareness of the symptoms of Q fever and the appropriateness of general biosecurity measures, especially among at‐risk groups living there.
Phylogeography and systematics ofAlgyroides(Sauria: Lacertidae) of the Balkan Peninsula
Authors: Strachinis Ilias , Poulakakis Nikos , Karaiskou Nikoleta , Patronidis Politis , Patramanis Ioannis , Poursanidis Dimitris , Jablonski Daniel , Triantafyllidis Alexandros 
Published: January 2021

AbstractThe area of the south‐western Balkans hosts a remarkably high species richness and has been considered a biodiversity hotspot. The significance of the Balkan Peninsula as a biodiversity refugium during the Quaternary climatic fluctuations has been repeatedly pointed out in literature, yet the area remains quite understudied in terms of phylogeography. Contributing to the biogeography and phylogeography of the Balkan area, we herein present the phylogeographic relationships within the lizards of the genusAlgyroides, focusing on the two species that occur in the Balkans (namely,A. nigropunctatusandA. moreoticus), including representatives ofDinarolacertaandLacertalizards as outgroups. We combined phylogenetic, phylogeographic and species distribution modelling analyses, using both mitochondrial and nuclear DNA data, in order to uncover the phylogeographic history of the genus and evaluate the validity of the extant taxonomy. Our results reveal three major clades withinAlgyroidesin southern Balkans; one corresponds toA. moreoticus, having sister group relationships with the genusDinarolacerta, and the other two toA. nigropunctatus, each corresponding to one of the morphological subspecies, which seem to be monophyletic, allopatric and reproductively isolated. These results expose an unprecedented phylogeographic pattern in the area of western Greece where the two major clades ofA. nigropunctatusmeet, and can contribute to a taxonomic re‐evaluation of the species. Moreover, questions are raised on the validity ofDinarolacertaas a genus due to it clustering within the genusAlgyroides.
Fabrication of Optical Fiber Sensors Based on Femtosecond Laser Micro Machining
Authors: Zhou Fengfeng , Jo Seunghwan , Fu Xingyu , Tsai Jung-Ting , Jun Martin Byung-Guk 
Published: January 2021

Abstract
In this research, we proposed fabrication process of optical fiber sensors using femtosecond laser and their applications. A beam of femtosecond laser was focused by an objective lens in the optical fiber. By testing different conditions, a group of machining parameters was found that achieve a minimum machining resolution of 3.2 μm. To ablate the core of the optical fiber, which is buried deep inside the cladding, precisely, part of the cladding was removed to expose the core as close as possible to the air. By making a complex pattern to modify the optical path of the laser inside an optical fiber, a sensitivity of 942.8–1015.6 nm per refractive index unit (nm/RIU) was obtained for liquid refractive index sensing. For another sensor, a sensitivity of 1.38 × 105 nm/RIU was obtained, which is high enough to detect small amount of refractive index change of air. It is known to be the first time that we fabricated a complex microstructure in an optical fiber to modify the propagation of the light using femtosecond laser. This research shows the possibility of a complex modification of light in an optical fiber using laser machining.
A Comprehensive Study on Burst Pressure Performance of Aluminum Liner for Hydrogen Storage Vessels
Authors: Kangal Serkan , Harun Sayı A. , Ayakdaş Ozan , Kartav Osman , Aydın Levent , Seçil Artem H. , Aktaş Engin , Yücetürk Kutay , Tanoğlu Metin , Kandemir Sinan , Beylergil Bertan 
Published: January 2021

Abstract
This paper presents a comparative study on the burst pressure performance of aluminum (Al) liner for type-III composite overwrapped pressure vessels (COPVs). In the analysis, the vessels were loaded with increasing internal pressure up to the burst pressure level. In the analytical part of the study, the burst pressure of the cylindrical part was predicted based on the modified von Mises, Tresca, and average shear stress criterion (ASSC). In the numerical analysis, a finite element (FE) model was established in order to predict the behavior of the vessel as a function of increasing internal pressure and determine the final burst. The Al pressure vessels made of Al-6061-T6 alloy with a capacity of 5 L were designed. The manufacturing of the metallic vessels was purchased from a metal forming company. The experimental study was conducted by pressurizing the Al vessels until the burst failure occurred. The radial and axial strain behaviors were monitored at various locations on the vessels during loading. The results obtained through analytical, numerical, and experimental work were compared. The average experimental burst pressure of the vessels was found to be 279 bar. The experimental strain data were compared with the results of the FE analysis. The results indicated that the FE analysis and ASSC-based elastoplastic analytical approaches yielded the best predictions which are within 2.2% of the experimental burst failure values. It was also found that the elastic analysis underestimated the burst failure results; however, it was effective for determining the critical regions over the vessel structure. The strain behavior of the vessels obtained through experimental investigations was well correlated with those predicted through FE analysis.
Bistability in Cylindrical Developable Mechanisms Through the Principle of Reflection
Authors: Butler Jared , Greenwood Jacob , Howell Larry L. , Magleby Spencer 
Published: January 2021

Abstract
We present a resource for designing bistable developable mechanisms (BDMs) that reach their second stable positions while exterior or interior to a cylindrical surface. Analysis of the necessary conditions to create extramobile and intramobile cylindrical BDMs is conducted through a series of three tests. These tests contain elements of both existing and new mechanism design tools, including a novel graphical method for identifying stable positions of linkages using a single dominant torsional spring, called the principle of reflection. These tests are applied to all possible mechanism cases and configurations to identify why certain configurations will always, sometimes, or never be a BDM. Two tables summarize these results as a guide when designing extramobile and intramobile BDMs. The results are compared and demonstrated with a numerical simulation of 30,000+ mechanisms, including several example mechanisms that illustrate the concepts discussed in the work. Discussion is then provided on the implication of these results.