bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tareas educativas interactivas, motivación y estrategias de aprendizaje, en educación primaria, a partir de un curriculum modulado por nuevas tecnologías
Authors: Expósito López Jorge , Manzano García Beatriz 
Published: July 2021

Las intervenciones educativas comienzan a desarrollarse en contextos novedosos, como los ámbitos digitales y/o virtuales, de una complejidad creciente en cuanto al manejo de la información por parte de los sujetos. En éstos son tan importantes, desde una perspectiva funcional, el aprendizaje de contenidos conceptuales, como la capacidad de desarrollar procedimientos.
La enseñanza de estrategias de aprendizaje, es una respuesta para la capacitación de los sujetos en el uso de las herramientas que les permitan desenvolverse con fluidez en situaciones muy características en estos nuevos ámbitos educativos, de aprendizaje cambiantes y diversos.
Los estudios que, desde diversas perspectivas e incidiendo en diversas dimensiones, denotan que los beneficios del empleo de las TIC’s en el ámbito educativo son numerosos. Este trabajo describe las estrategias de aprendizaje que utiliza un grupo de alumnado de Educación Primaria, cuando realiza tareas educativas interactivas moduladas por el uso de las TIC’s, constatando igualmente la influencia positiva de la realización de esta tipología de tareas sobre la motivación del alumnado.
GCK-MODY diabetes course in persons over 18 years of age: prospective observation
Authors: Ovsyannikova A. K. , Shakhtshneider E. V. , Ivanoshchuk D. E. , Voevoda M. I. , Rymar O. D. 
Published: July 2021

Most young patients with hyperglycemia have type 1 diabetes and type 2 diabetes but up to 10% of all cases of the disease occur in MODY (Maturity Onset Diabetes of the Young). Published abstracts show features of the debut, laboratory and genetic characteristics of MODY in the Russian population. However there is a small amount of data on the clinical course of this nosology in the Russian Federation.Aim: To investigate the characteristics of the 3-year course of GCK-MODY diagnosed after 18 years.Materials and methods: 85 probands and 46 relatives of the first and second degrees of kinship with a clinical diagnosis of GCK-MODY were examined: biochemical and hormonal blood tests, ultrasound, molecular genetic studies. Patients were invited for a follow-up visit 3 years after verification of the pathogenic mutations associated with GCK-MODY. Examination, biochemical and hormonalanalyzes , ultrasound were done in second visit.Results: The diagnosis GCK-MODY was verified by a molecular genetic study in 25 probands (29.4%). In 33 of 46 (71.7%) relatives of patients with GCK-MODY were diagnosed identical mutations. In 31 patients with GCK-MODY diagnosed after 18 years, a dynamic observation was performed for three years. Most patients over 18 years of age did not have clinical manifestations of carbohydrate metabolism disorders when diagnosing GCK-MODY and follow up visit. Skin rashes and allergic reactions prevailed among concomitant pathologies. Patients with GCK-MODY had preserved β-cell secretion, HbA1c targets were achieved. Low fasting hyperglycemia prevailed which persisted even after treatment correction. Among the characteristics of carbohydrate metabolism, biochemical, lipid and hormonal parameters during GCK-MODY verification and after three years of observation no significant differences were obtained, which indicates a stable course of the disease. Half of the patients achieved normoglycemia by rational nutrition, two people with GCK-MODY within three years after determining the diagnosis were transferred from insulin therapy to oral glucose-lowering drugs. Among oral glucose-lowering drugs prior to GCK-MODY verification most patients used metformin, 3 years later — dipeptidyl peptidase-4 inhibitors.Conclusion. The results of a three-year follow-up of a group of patients with GCK-MODY demonstrate a non-progressive course of this type of diabetes with stable indicators of carbohydrate metabolism and low fasting hyperglycemia that persists after 3 years of observation. With the verification of GCK-MODY and the achievement of the target values of glycated hemoglobin and postprandial glycaemia by rational nutrition, even if a low level of fasting hyperglycemia is determined, the prescription of oral glucose-lowering drugs is not indicated in most cases.
Kant’s Mereological Account of Greater and Lesser Actual Infinities
Authors: Smyth Daniel 
Published: July 2021

Abstract
Recent work on Kant’s conception of space has largely put to rest the view that Kant is hostile to actual infinity. Far from limiting our cognition to quantities that are finite or merely potentially infinite, Kant characterizes the ground of all spatial representation as an actually infinite magnitude. I advance this reevaluation a step further by arguing that Kant judges some actual infinities to be greater than others: he claims, for instance, that an infinity of miles is strictly smaller than an infinity of earth-diameters. This inequality follows from Kant’s mereological conception of magnitudes (quanta): the part is (analytically) less than the whole, and an infinity of miles is equal to only a part of an infinity of earth-diameters. This inequality does not, however, imply that Kant’s infinities have transfinite and unequal sizes (quantitates). Because Kant’s conception of size (quantitas) is based on the Eudoxian theory of proportions, infinite magnitudes (quanta) cannot be assigned exact sizes. Infinite magnitudes are immeasurable, but some are greater than others.
The Role of Animal in Abū Bakr al-Rāzī’s Theory of the Perfection of the Soul
Authors: Montaseri Mohammad Mehdi , Faramarz-Qaramaleki Ahad 
Published: July 2021

Abstract
Abū Bakr al-Rāzī (d. ca. 925), a well-known physician and Muslim philosopher, has not yet been widely considered for his philosophical reflections on animals. An inspection of al-Rāzī’s works demonstrates his endeavor, based on his cosmology, to come up with a way of the perfection of the soul and becoming liberated from the terrestrial world. As this paper maintains, his investigation of animals is aimed at developing his theory of the perfection of the soul. After a brief clarification of the theory, which entails a discussion of the interaction of the two theoretical and practical aspects of human reason, this paper will discuss seven cases in which al-Rāzī uses the discussion of animals to develop his theory of the perfection of the soul.
The Effects of Pre-Task Planning on Second Language Writing: A Systematic Review of Experimental Studies
Authors: Ellis Rod 
Published: July 2021

Abstract
There are both pedagogical and theoretical grounds for asking second language writers to plan before they start writing. The question then arises whether pre-task planning (PTP) improves written output. To address this question, this article reviewed 32 studies by comparing the effect of PTP either with no planning or with unpressured online planning (OLP). These studies also investigated the moderating effect of variables relating to the writer participants, the nature of the planning, and the writing tasks. The main findings are: (1) There is no clear evidence that PTP leads to better overall writing quality when this is measured using rating rubrics, (2) PTP generally results in more fluent writing, (3) its impact on syntactical and lexical complexity is inconsistent and negligible, (4) OLP does sometimes result in increased linguistic accuracy, and (5) there is insufficient evidence to reach clear conclusions about the role that moderating variables have on the impact of PTP, but the results suggest that collaborative (as opposed to individual planning) can lead to increased accuracy and that PTP tends to lead to more complex language when the writing task is a complex one. The article concludes with a set of principles to ensure better quality research and three general proposals for the kind of future research needed.
Investigating Affordance in Technology-Enriched Language Learning Environment Through Exploring Students’Perezhivanija
Authors: Qin Lili , Wei Ren 
Published: July 2021

AbstractPreceding works tend to explicate affordance through supposing what is happening here and now. They seldom relate it to actual social, diachronic activities, such as foreign language learning. To tackle this issue, this study explores how students actualize affordances in technology-enriched language learning environment (TELLE) by examining their perezhivanija (lived and emotional experience), a term borrowed from sociocultural theory. Because an individual’s social life is a developing process or aperezhivaniePerezhivanieis the singular form of perezhivanija., it is necessary to base the research in a dynamic development of language learning to figure out how the affordances are actualized. Narrative interviews were adopted to collect data from three Chinese college students who learn English as a foreign language in a Northeastern university in China. The results showed that due to the students’ different past perezhivanija in English learning, their present interpretations of the perceived affordances in TELLE varied. This influenced hugely in their actions taken during their English learning in college to actualize the affordances. The findings indicated that the actualization of affordances is historical, dynamic and developmental instead of static. It does not lie in the autonomy of the students or the teachers, but in the institutional and cultural legitimacy of technology use in student’s social life. The paper contributes to the application of affordance theory in foreign language learning and provides implications to language teaching practice in TELLE.
Does Start-Up Founding Strategy Increase or Decrease the Effects of Strategic Capabilities on New Venture Performance?
Authors: Zhang Haili , Hao Shengbin , Song Michael 
Published: July 2021

Abstract
Many studies have provided evidence of a positive relationship between strategic capabilities and new venture performance. This study applies the resource-based view and strategic fit theory to develop a model that investigates how startup founding strategy affects the strength of the strategic capabilities–performance relationship in new ventures. We conduct an empirical study of 146 U.S. new ventures and 425 Chinese new ventures to test the proposed model. The results show that, for U.S. ventures, technology-driven strategy increases the effect of technology capabilities on new venture performance but decreases the effects of marketing and market-linking capabilities on new venture performance. By contrast, Chinese ventures' technology-driven strategy has a significantly negative moderating effect on the relationship between market-linking capabilities and performance. We discuss the implications of the empirical findings for ventures pursuing technology-driven and market-driven strategies.
Antibiofilm action of Persea americana glycolic extract over Acinetobacter baumannii and absence of toxicity in Galleria mellonella
Authors: dos Santos Liberato Sabrina Ferreira , da Cruz Vegian Mariana Raquel , Abu Hasna Amjad , de Alvarenga Janaína Araújo , dos Santos Juliana Guimarães , Tini Ítalo Rigotti Pereira , Amêndola Isabela , Junqueira Juliana Campos , de Oliveira Luciane Dias 
Published: July 2021

Abstract

Objectives
This study aimed to evaluate the antibiofilm activity and toxicity of the glycolic extract of Persea americana “P. americana” over multidrug-resistant strains of Acinetobacter baumannii “A. baumannii” as alternative therapy to be investigated.

Methods
A bacterial inoculum of each bacterial strain (4a, 5a, 9a, 12a, ATCC 19606) of A. baumannii was prepared and adjusted by the spectrophotometer. The microdilution broth method was performed to determine the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). P. americana glycolic extracts were obtained of the tree stalk and leaves. The biofilm viability was tested by MTT assay after 5 min exposure. The toxicity of the extracts was tested by invertebrate model Galleria mellonella. The data were analyzed by ANOVA, Tukey test and log-rank method (α=0.05).

Results
The extract showed an inhibitory and bactericidal action over all the tested strains with the lowest MIC value observed for the reference strain (3.12 mg/mL). The extract did not demonstrate toxicity in any of the tested concentrations (12.5, 25 and 50 mg/mL) in Galleria mellonella larvae, with a survival percentage above 80% after 168 h.

Conclusions
The glycolic extract of P. americana has microbicidal and antibiofilm activity on multidrug-resistant clinical strains of A. baumannii and showed low toxicity for the invertebrate model G. mellonella.
Effect of Ḥijāma (wet cupping), Dalk (massage) and Bukhūr (medicated steam) in amelioration of Waja al-Zahr (non-specific low back pain) – an open prospective clinical trial
Authors: Ahmed Noor Zaheer , Anwar Noman , Begum Shahida , Parvez Athar , Ezhil Radhakrishnan , Anjum Nighat 
Published: July 2021

Abstract

Objectives
Low back pain is the most widespread musculoskeletal ailment and a common cause of disability worldwide. Conventional medicine typically treats low back pain with a combination of physical therapy; activity modification and rest; pain-relieving and anti-inflammatory medications which are associated with huge socioeconomic implications and adverse drug reactions. In contrast Ḥijāma, Dalk and Bukhūr are ancient medical techniques recommended in the management of musculoskeletal disorders with little or no adverse effects. To evaluate the safety and effectiveness of Ḥijāma bi’l Shart (wet cupping), followed by Dalk (Massage) with Roghan Dafli and Bukhūr (medicated steam) with Tukhm Soya (Anethum graveolens Linn) in patients of Waja al-Zahr (Non-specific Low back pain).

Methods
Patients of either gender in the age group of 18–50 years with low back pain persisting for four weeks or more as chief complaint were recruited in the trial. The study was GCP compliant. The duration of the protocol therapy carried out was 14 days.

Results
Ninty two patients of NSLBP were screened, of which 34 who fulfilled the inclusion criteria and were willing to participate in the study were recruited. Three participants were lost to follow-ups due to personal reasons and 31 patients completed the trial during the study period. Overall therapeutic response observed in this study was 97% while 3% of the patients did not respond to intervention.

Conclusions
The study findings imply that there is a credible evidence to ensure that the regimens intervened are safe and effective in ameliorating the symptoms of Waja al-Zahr.
Primary orbital ganglioneuroblastoma: A case report
Authors: Ma Ruixin , Wang Yujiao , He Weimin 
Published: July 2021

Abstract

Background
Ganglioneuroblastoma (GNB) is a neoplasm that arises from the primitive cells of the sympathetic nervous system during childhood. The current case is very unique because of the initial primary tumor manifestation in the orbit and an adrenal tumor being observed later during follow-up.

Case presentation
A 2-year-old girl presented to the Ophthalmology Department of our hospital complaining of swelling of the left upper eyelid for approximately one month. Orbital computed tomography (CT) revealed a left orbital mass with bone destruction. Thoracic and abdominal CT indicated no abnormalities. The mass was surgically resected, and histopathological analysis confirmed it as GNB. During follow-up, abdominal CT detected an adrenal tumor with internal calcification, a calcified nodule on the left side of the abdominal aorta, and mesenteric lymph nodes. Accordingly, primary orbital GNB and metastatic adrenal GNB were the possible considerations. We removed the adrenal tumor, and the patient underwent chemotherapy. However, the patient died 18 months after the ophthalmic surgery.

Conclusion
Primary orbital GNB in children is easily misdiagnosed because of its rare occurrence and atypical clinical findings. Imaging methods combined with histopathological examination contribute to the detection and diagnosis of primary and metastatic GNBs. Thus, timely surgery combined with adjuvant chemotherapy and long-term follow-up is essential for controlling the metastasis of GNB and improving the survival rate of patients.
Automated argument adjudication to solve ethical problems in multi-agent environments
Authors: Bringsjord Selmer , Govindarajulu Naveen Sundar , Giancola Michael 
Published: July 2021

AbstractSuppose an artificial agentaadj{a}_{\text{adj}}, as time unfolds, (i) receives from multiple artificial agents (which may, in turn, themselves have received from yet other such agents…) propositional content, and (ii) must solve an ethical problem on the basis of what it has received. How shouldaadj{a}_{\text{adj}}adjudicate what it has received in order to produce such a solution? We consider an environment infused with logicist artificial agentsa1,a2,…,an{a}_{1},{a}_{2},\ldots ,{a}_{n}that sense and report their findings to “adjudicator” agents who must solve ethical problems. (Many if not most of these agents may be robots.) In such an environment, inconsistency is a virtual guarantee:aadj{a}_{\text{adj}}may, for instance, receive a report froma1{a}_{1}that propositionϕ\phiholds, then froma2{a}_{2}that¬ϕ\neg \phiholds, and then froma3{a}_{3}that neitherϕ\phinor¬ϕ\neg \phishould be believed, but ratherψ\psiinstead, at some level of likelihood. We further assume that agents receiving such incompatible reports will nonetheless sometimes simply need, before long, to make decisions on the basis of these reports, in order to try to solve ethical problems. We provide a solution to such a quandary: AI capable of adjudicating competing reports from subsidiary agents through time, and delivering to humans a rational, ethically correct (relative to underlying ethical principles) recommendation based upon such adjudication. To illuminate our solution, we anchor it to a particular scenario.
Monascin and monascinol, azaphilonoid pigments from Mortierella polycephala AM1: in silico and in vitro targeting of the angiogenic VEGFR2 kinase
Authors: Shaaban Mohamed , Magdy El-Metwally Mohammad , Mekawey Amal A. I. , Abdelwahab Ahmed B. , Soltan Maha M. 
Published: July 2021

Abstract
The fungus, Mortierella polycephala is one of the most productive sources of anticancer bioactive compounds namely those of pigment nature. During our investigation of the produced bioactive metabolites by the terrestrial M. polycephala AM1 isolated from Egyptian poultry feather waste, two main azaphilonoid pigments, monascin (1) and monascinol (2) were obtained as major products; their structures were identified by 1D (1H&13C) and 2D (1H–1H COSY, HMBC) NMR and HRESI-MS spectroscopic data. Biologically, cytotoxic activities of these compounds were broadly studied compared with the fungal extract. To predict the biological target for the presumed antitumor activity, an in silico study was run toward three proteins, topoisomerase IIα, topoisomerase IIβ, and VEGFR2 kinase. Monascinol (2) was expected to be moderately active against VEGFR2 kinase without any anticipated inhibition toward topo II isoforms. The in vitro study confirmed the docked investigation consistently and introduced monascinol (2) rather than its counterpart (1) as a potent inhibitor to the tested VEGFR2 kinase. Taxonomically, the fungus was identified using morphological and genetic assessments.
Elasticity of the Flexor Carpi Ulnaris Muscle After an Increased Number of Pitches Correlates With Increased Medial Elbow Joint Space Suppression
Authors: Saito Akira , Namiki Yusuke , Okada Kyoji 
Published: July 2021

Abstract
Saito, A, Namiki, Y, and Okada, K. Elasticity of the flexor carpi ulnaris muscle after an increased number of pitches correlates with increased medial elbow joint space suppression. J Strength Cond Res 35(9): 2564–2571, 2021—This study aimed to measure the medial elbow joint space and elasticity of the forearm flexor-pronator muscles in repetitive pitching and to determine which of the forearm flexor-pronator muscles contribute to elbow valgus stability during pitching. Twenty-six collegiate baseball players performed 7 sets of 15 pitches. The medial elbow joint space and elasticity of the pronator teres, flexor carpi radialis, flexor digitorum superficialis (FDS), and flexor carpi ulnaris (FCU) were measured using ultrasonography before pitching and after every 15 pitches. Correlations among the rate of change of these parameters were analyzed using Pearson's correlation coefficients. The medial elbow joint space increased after 60 or more pitches compared with that before pitching (all p < 0.001; effect size [ES]: 0.44–1.22). FDS and FCU elasticity increased after 45 and 60 pitches or more in contrast to that before pitching, respectively (FDS: p = 0.047 and p < 0.001, respectively; ES: 1.05–1.42, FCU: p = 0.011 and p < 0.001, respectively; ES: 1.11–1.48). After 75 or more pitches, the rate of change of FCU elasticity correlated negatively with that of the medial elbow joint space (r = −0.395, r = −0.454, and r = −0.404, after 75, 90, and 105 pitches, respectively). Increased FCU elasticity after repetitive pitching correlated with suppression of the increase of the medial elbow joint space. The FCU may be the primary dynamic stabilizer against the elbow valgus force, and evaluation of the FCU elasticity may be important for preventing elbow injuries.
Field Collection of Geotechnical Measurements for Remote or Low-Cost Datalogging Requirements
Authors: Sattler Kelvin , Elwood David , Hendry Michael T. , Berscheid Brian , Marcotte Bryce , Abdulrazagh Parisa Haji , Huntley David 
Published: July 2021

AbstractReliable, low-cost datalogging alternatives promote transfer of knowledge and technology to the wider geotechnical and geoscientist community. Alternative systems can ease increased data resolution on large projects, operate in remote locations with restricted site access, or allow developing countries access to reliable and cost-effective datalogging solutions. A low-cost prototype datalogger was developed and tested in the laboratory with the use of open-source materials. Open-source example code is provided at the permanent links included in this paper. The materials for the prototype were 20 % the cost of commercial datalogging units with similar capabilities. With labor, these custom-built units were 35–45 % the cost of a purchased datalogger. Measurements from commercial units and the prototype datalogger were compared to determine the prototype’s accuracy. The datalogger was deployed in place of commercially available dataloggers at three sites across western Canada in the past two years. Laboratory and field testing of the low-cost datalogger has shown the prototype to be easily adaptable to various sensor types. The study experimented with negative pore water pressure (matric suction), volumetric water content, and temperatures from SDI-12 sensors as well as positive pore water pressure and temperature from vibrating wire piezometers. Telemetry modules have been attached to remote dataloggers, transmitting occasional data points, and periodically verifying system operation. Assembly, installation, and monitoring with the low-cost datalogging system over the past two years has demonstrated their durability in field applications. The implementation of a low-cost, open-source geotechnical datalogging system can be a challenge in some locations and requires the consideration of limitations, which are addressed.