bluuebunny/crossref_metadata_2025_split huggingface dataset:
New Insight into the development of deformation texture in face-centered cubic material
Authors: shankar Gyan , Kumar Deepak , Suwas Satyam 
Published: April 2021

Abstract
Despite a tremendous amount of research to understand the evolution of microstructural and texture changes during deformation, there is still a need for further deep insight into it. The most used deformation process underuse in industries is the rolling of material. Stacking fault energy is the most critical material property, which governs the deformation behavior. In the present study, the microstructure and texture changes of a high SFE material (pure nickel) during cold rolling was investigated. The objective is to find criteria for the change of orientation of a particular grain as rolling proceed. Pseudo-in-situ rolling was done through which the shape, orientations, and neighbors of each grain could be tracked as a function of rolling reductions. It was found that orientations of some grains remain stable after a large reduction and do not develop sub-grains within it, whereas orientations of some grains change drastically at a very low deformation level along with the evolution of a large number of sub-grains.
Change in intragranular misorientation during stress relaxation behavior in Cu-Ni-Si alloy subjected to continuous cyclic bending
Authors: Fukutomi Tatsuya , Komei Narumi , Takayama Yoshimasa , Watanabe Hideo 
Published: April 2021

Abstract
Stress relaxation resistance is often required in application of electrical parts for copper and its alloys. The stress relaxation behavior should be influenced by stored strain through manufacturing process. In the present study, a Cu-Ni-Si alloy solution-treated sheet was subjected to continuous cyclic bending (CCB), which was proposed as a useful straining technique to impose higher strain on the surface and lower strain in the center layer of metal sheets. Samples were analyzed by scanning electron microscope / electron back scatter diffraction (SEM/EBSD) technique to investigate stored strain and stress relaxation process. CCB raised up the strength of Cu-Ni-Si alloy sheets at room temperature. The stress relaxation ratios of the CCBent sheets increased with an increment of test exposure time at 423K. The stress relaxation process was accompanied with change in intragranular misorientation of the samples. Change in intragranular misorientation through the stress relaxation test was understood as a result of release of residual and applied stresses with consumption of stored strain.
The influence of the crystallographic texture and phase composition of Ti-Nb-Zr alloys with shape memory and superelasticity on their functional properties
Authors: Zaripova M M , Isaenkova M G , Fesenko V A , Osintsev A V 
Published: April 2021

Abstract
Currently, Ti-Zr-Nb-based biocompatible alloys are considered as prospective for medical applications. In this work, the mechanisms of the formation of the crystallographic texture of five alloys Ti-(17-19)Zr-(14-16)Nb (at.%) have been compared. The presence of martensitic transformations during the rolling process determines the features of the formed texture. At the initial stage of deformation (ε = 50%), the texture {112}<011> is formed in all five alloys. With an increase of the degree of deformation to 92%, the texture dissipates somewhat, which is due to an increase in the fraction of the martensitic phase in the foils. Recrystallization of rolled foils (ε = 92%) at 650°C leads to an exacerbation of the texture component close to {100}<011>, the blurring of which varies in different alloys. Cyclic tensile tests along three directions: the rolling direction (RD), the transverse direction, at an angle of 45° to the RD showed the presence of anisotropy in the samples. It was shown, that the effect of superelasticity is orientation-and structure-depending, and the anisotropy of mechanical properties.
Microstructural study of duplex stainless steel after turning using EBSD and X-ray diffraction analysis
Authors: Capek J , Minarik P , Neslusan M , Trojan K , Ganev N 
Published: April 2021

Abstract
The aim of this research is a microstructural study of duplex stainless steel after turning. The electron backscatter diffraction and X-ray diffraction analyses were applied to analyse the surface and subsurface regions. The gradients of Kernel Average Misorientation as a function of flank wear were investigated. It was found that the concentration of deformation depends on the subsurface depth, individual phases, and flank wear. The similar behaviour but with a different inclination of grain size (determined by electron backscatter diffraction) and crystallite size (determined by X-ray diffraction) depending on flank wear was observed.
Dependence of Thermal Expansion of Zr-Based Products on their Crystallographic Texture
Authors: Stolbov Sergey , Isaenkova Margarita , Perlovich Yuriy , Tenishev Andrey , Krymskaya Olga , Mikhalchik Vladimir , Klyukova Kristina 
Published: April 2021

Abstract
The accident at Fukushima Daiichi in 2011 highlighted the increased interest in predicting the materials properties under extreme conditions. In this work, it is considered the behaviour of cubic samples cut from the wall of channel tubes made of Zr-2.5% Nb alloy during heating and cooling in the temperature range of 20-1200 °C. The anisotropy of changes in the dimensions of cubic samples in different structural states has been studied. Thermal tests were carried out in three mutually perpendicular directions: radial, tangential and axial. The structural state of tubes was estimated from the features of their crystallographic texture. The significant anisotropy of the size change is observed in the Zr-2.5%Nb alloy product with an unstable crystallographic texture of deformation due to the α↔β-phase transformation inhomogeneity. In the case of complete recrystallization and orientation of the <1120> axes along the tube axis, the anisotropy of the dimensions change is minimal, due to uniform nuclei formation of new phases in different orientations.
Evaluation of active slip systems during deformation by Insitu XRD in precipitation hardening Mg Alloys
Authors: Yoshikawa Tomoki , Hirata Masahiro , Okai Daisuke , Adachi Hiroki 
Published: April 2021

Abstract
The effect of precipitates on active slip systems was evaluated in precipitation-hardening Mg Alloys. In a Mg-5% Y-4% Nd (WE54) alloy, the radius and thickness of disc-shaped β“ precipitates were measured by small angle X-ray scattering measurements. The active slip system was then measured during tensile deformation by in situ X-ray diffraction measurements. The average radius and thickness of the precipitates increased with aging time, and approached 19.4 and 3.85 nm, respectively, at a peak aging time of 2160 ks. The uniform elongations of the as-quenched, 1.08 ks aged and 36Q ks aged alloys were determined to be approximately 9.7, 5.5 and 2.3%, respectively. Various slip systems were active in the as-quenched alloy. On the other hand, in the alloy aged for 360 ks, non-basal <a> slip was found to be dominant.
Influence of parameters of gas-dynamic spraying on substructure of “brass” coating type
Authors: Arkhipov V E , Moskvitin G V , Pugachev M S 
Published: April 2021

Abstract
Investigations of the influence of the parameters of applying a gas-dynamic coating of copper-zinc on its substructure have been carried out. It was found that the coating has a gradient hardness and different phase composition. Increasing the temperature of spraying and coating with 3mm overlap leads to a decrease in the size of the substructures. The structure of the coating, which is gradient in phase composition and hardness, should provide high tribotechnical characteristics of the friction surface in contact.
Influence of additional vibration loads on the processes of deformation and fracture of composite tubular samples
Authors: Wildemann Valerii , Staroverov Oleg 
Published: April 2021

Abstract
The work is devoted to an experimental study of the influence of additional vibration torsional effects on the deformation and fracture of composite tubular specimens under quasistatic tensile stress. A series of tests with various parameters of torsional vibration load for thin-walled CFRP tubular samples were performed according to the developed method. As part of the work, the methodological aspects of testing tubular specimens are considered. As a result, experimental data were obtained that reflect the effect of vibration effects on the behaviour of composite specimens during quasi-static tension. Additional vibrations contributed to the implementation of the deformation resources of the composite structural elements.
Exploration of strength characteristics quadrocopter frame structure obtained using 3d printing technology
Authors: Navrotsky R A , Moskvitin G V , Naumov O V , Pugachev M S 
Published: April 2021

Abstract
This article discusses the use of 3D printing technology for manufacturing the frame structure of a quadrocopter. The strength of the plastic frame structure is calculated. The results obtained allow us to draw conclusions about the possibility of using this technology for the production and operation of aircraft of the quadrocopter type.
On the strength of chemical anchors
Authors: Titov O V , Nadezhdin V S , Gruzdev A S , Kuprin A V 
Published: April 2021

Abstract
The work presents the strut attachment unit study of the bridge barrier road rack to the reinforced concrete slab (strength class of concrete B35) using adhesive (chemical) compositions and anchor-studs under the dynamic load. Bench static tests results and virtual experiment results based on study of digital models presented. The required depth of anchor-stud deepening determined.
Solving one dimensional time-space fractional vibration string equation
Authors: Aleroev Temirkhan S. , Elsayed Asmaa M. , Mahmoud Elsayed I. 
Published: April 2021

Abstract
The article presents a solution for the one-dimensional space-time fractional vibration equation (FVE) by the separation of variables method (Fourier method). We describe the fractional derivatives in the sense of Caputo and Riemann-Liouville operators. Our method performs in the extreme well in terms of simplicity and efficiency. A sample of the problem of structural mechanics has been considered. This sample allows the demonstration of some advantages of the application of the suggested approach to solve the fractional vibration equation.
Investigation of the stability of a cantilevered pipeline with a fluid flow compressed at the free end by the tracking force
Authors: Kapitanov D V , Kapitanova O V , Bobylkov A G 
Published: April 2021

Abstract
The paper presents a numerical and analytical investigation of the stability of a cantilevered pipeline transporting an incompressible fluid flow at a constant speed compressed by tracking force at the free end. To solve the problem, a dynamic approach based on the analysis of the behavior of the system’s own characteristics is used. In contrast to the classical research approaches, which are based on the representation of the solution of the problem using a finite number of basic functions, an algorithm that does not require such a restriction is proposed.
Analytical modelling of the influence of temperature and capillary diameter on the sonocapillary effect for liquids with different density
Authors: Mikhailova N , Smirnov I 
Published: April 2021

Abstract
The paper examines an approach to calculating the sonocapillary effect. The proposed model for calculating the initial sonocapillary pressure considers the temperature and density of a liquid, the capillary diameter, and the ultrasound frequency. The calculations are based on the incubation time criterion of cavitation. This approach allows us to find the threshold cavitation amplitude of ultrasound for a given frequency and to estimate the corresponding sonocapillary pressure. The calculation results show that the sonocapillary pressure is directly related to the liquid density, increasing the capillary diameter reduces the intensity of the sonocapillary effect, and a rising temperature increases the sonocapillary pressure. However, minimal experimental data are available at present to verify the obtained theoretical results. Therefore, a wider range of new experimental results should be obtained for further studies of the sonocapillary effect based on the presented results.
Features of the dynamics of walking machines and robots with cycle type of movers and controlled dissipation in the foot joint
Authors: Arykantsev V V , Kalinin Ya V , Chernyshev V V 
Published: April 2021

Abstract
The expediency of introducing an additional damping device (analog of a shock absorber) into the cyclic walking mechanism of a mobile robot, which provides a dissipative connection of a ski-shaped foot with a support link, is discussed. The influence of the damper on the dynamics of the feet changing and the dynamics of the meeting of the foot with an obstacle is considered. It is shown that dissipation in the hinge of the foot leads to a decrease in the intensity of shock processes when changing feet and when meeting an obstacle, provides a decrease in power losses for vertical vibrations of the body, and also expands the propulsion unit’s capabilities for self-adaptation to an unorganized surface.
Loading and transport unit with a tripod manipulator and hybrid drive
Authors: Nikolaev M E , Nesmianov I A , Ivanov A G , Dyashkin-Titov V V 
Published: April 2021

Abstract
The analysis of loading and transport operations during the harvesting of vegetables Packed in bags or nets was carried out. The geometric parameters of the pincer grip are justified and analytical and graphical dependences of the required holding force for different bag masses are obtained. The device of a developed and manufactured loading and transport unit with a tripod manipulator is described. The tasks of further research are defined.
Increasing the level of the metrological supply of large-sized windows blades (from 60m) at the production stages
Authors: Sinitsa M O 
Published: April 2021

Abstract
The development of the field of renewable energy sources today is happening at a fairly rapid rate, especially in the field of wind energy. In the last year alone, several large wind farms have been built in Russia. The fast pace of development of wind energy in Russia leads to the fact that in the near future there will be a need to produce our own wind turbines, according to the projects of Russian developers. Also, the development of technologies, the rapid introduction of new production systems, an increase in the share of autonomy of industrial enterprises requires the introduction of new modern approaches in the field of energy, energy efficiency and energy conservation. Against this background, the need for innovative solutions in the field of metrological support and measuring technologies in the energy sector is sharply increasing. The paper presents a complex for carrying out control and measuring procedures, which will improve the quality of metrological support in the production process in Russia. Also, the metrological and economic parameters of the described stand have been calculated.…
Developing of transport airship for delivery oversized cargo to Vostochny Cosmodrome
Authors: Didkovskij A A , Mukhina E D , Chernov A K 
Published: April 2021

Abstract
The analysis of the world experience in the creation of airships has been carried out and the most actual tasks for such devices in the field of rocket and space technology have been revealed. The appearance of a transport airship with a carrying capacity of 100 tons has been developed and its main technical parameters have been defined.
Tobacco and Cannabis Use During Pregnancy
Authors: Hunsaker Joshua J H , La’ulu Sonia L , LaGrave Danielle , Murphy Wendy , Reichman Heather A , Snow Taylor M , McMillin Gwendolyn A , Johnson-Davis Kamisha L , Genzen Jonathan R 
Published: April 2021

Abstract

Objectives
Nicotine (NIC) use during pregnancy can influence markers used in biochemical maternal serum screening. This study was designed to determine prevalence of disclosed tobacco smokers in our patient population and to compare disclosed tobacco smoking status with the presence of serum nicotine and a common tetrahydrocannabinol (THC) metabolite.

Methods
A deidentified dataset of disclosed smoking status for quadruple (Quad) screens was obtained. Residual serum submitted for Quad screens was obtained from frozen storage and analyzed for NIC and THC metabolites.

Results
Of specimens that had corresponding responses to the smoking history question on the patient history form, 7.2% (n = 1,783 of 24,611) specified that the patient was a tobacco smoker. Of the 271 specimens biochemically analyzed for NIC and THC metabolites, disclosed tobacco smokers had the highest prevalence of detectable NIC and THC metabolites. THC product use was most prevalent in patients categorized as probable tobacco smokers based on cotinine concentrations, as well as in younger patients.

Conclusions
Prevalence and concentration of NIC and THC metabolites vary based on disclosed tobacco smoker status. Biochemical testing may increase sensitivity for the identification of NIC and THC status over self-reporting.
Use of failure modes and effects analysis to mitigate potential risks prior to implementation of an intravenous compounding technology
Authors: Feemster Agnes Ann , Augustino Melissa , Duncan Rosemary , Khandoobhai Anand , Rowcliffe Meghan 
Published: April 2021

Abstract

Purpose
The purpose of this study was to identify potential failure points in a new chemotherapy preparation technology and to implement changes that prevent or minimize the consequences of those failures before they occur using the failure modes and effects analysis (FMEA) approach.

Methods
An FMEA was conducted by a team of medication safety pharmacists, oncology pharmacists and technicians, leadership from informatics, investigational drug, and medication safety services, and representatives from the technology vendor. Failure modes were scored using both Risk Priority Number (RPN) and Risk Hazard Index (RHI) scores.

Results
The chemotherapy preparation workflow was defined in a 41-step process with 16 failure modes. The RPN and RHI scores were identical for each failure mode because all failure modes were considered detectable. Five failure modes, all attributable to user error, were deemed to pose the highest risk. Mitigation strategies and system changes were identified for 2 failure modes, with subsequent system modifications resulting in reduced risk.

Conclusion
The FMEA was a useful tool for risk mitigation and workflow optimization prior to implementation of an intravenous compounding technology. The process of conducting this study served as a collaborative and proactive approach to reducing the potential for medication errors upon adoption of new technology into the chemotherapy preparation process.
Pretraining model for biological sequence data
Authors: Song Bosheng , Li Zimeng , Lin Xuan , Wang Jianmin , Wang Tian , Fu Xiangzheng 
Published: April 2021

AbstractWith the development of high-throughput sequencing technology, biological sequence data reflecting life information becomes increasingly accessible. Particularly on the background of the COVID-19 pandemic, biological sequence data play an important role in detecting diseases, analyzing the mechanism and discovering specific drugs. In recent years, pretraining models that have emerged in natural language processing have attracted widespread attention in many research fields not only to decrease training cost but also to improve performance on downstream tasks. Pretraining models are used for embedding biological sequence and extracting feature from large biological sequence corpus to comprehensively understand the biological sequence data. In this survey, we provide a broad review on pretraining models for biological sequence data. Moreover, we first introduce biological sequences and corresponding datasets, including brief description and accessible link. Subsequently, we systematically summarize popular pretraining models for biological sequences based on four categories: CNN, word2vec, LSTM and Transformer. Then, we present some applications with proposed pretraining models on downstream tasks to explain the role of pretraining models. Next, we provide a novel pretraining scheme for protein sequences and a multitask benchmark for protein pretraining models. Finally, we discuss the challenges and future directions in pretraining models for biological sequences.
Capturing dynamic relevance in Boolean networks using graph theoretical measures
Authors: Weidner Felix M , Schwab Julian D , Werle Silke D , Ikonomi Nensi , Lausser Ludwig , Kestler Hans A 
Published: April 2021

AbstractMotivationInteraction graphs are able to describe regulatory dependencies between compounds without capturing dynamics. In contrast, mathematical models that are based on interaction graphs allow to investigate the dynamics of biological systems. However, since dynamic complexity of these models grows exponentially with their size, exhaustive analyses of the dynamics and consequently screening all possible interventions eventually becomes infeasible. Thus, we designed an approach to identify dynamically relevant compounds based on the static network topology.ResultsHere, we present a method only based on static properties to identify dynamically influencing nodes. Coupling vertex betweenness and determinative power, we could capture relevant nodes for changing dynamics with an accuracy of 75% in a set of 35 published logical models. Further analyses of the selected compounds’ connectivity unravelled a new class of not highly connected nodes with high impact on the networks’ dynamics, which we call gatekeepers. We validated our method’s working concept on logical models, which can be readily scaled up to complex interaction networks, where dynamic analyses are not even feasible.Availability and implementationCode is freely available at https://github.com/sysbio-bioinf/BNStatic.Supplementary informationSupplementary data are available at Bioinformatics online.
Study on the Pharmacokinetic Profiles of Three Ingredients in Qilong Capsules and Their Potential Interactions in Rats by LC–MS/MS
Authors: Liu Ruichen , Liang Huiliang , Li Zhen , Zang Hengchang 
Published: April 2021

Abstract

Qilong capsule (QLC) is a well-known Traditional Chinese Medicine, and it has a long history for the treatment of ischemic stroke. Its major ingredients are saponins, such as paeoniflorin, amygdalin and calycosin-7-glucoside, contributing to vasodilation function. In this study, a simple, rapid and sensitive high-performance liquid chromatography-tandem mass spectrometry method was developed to determine three bioactive ingredients in rat plasma after oral administration of QLC. A simple acetonitrile precipitation method was introduced during the sample preparation. Chromatographic separation was performed on a Shiseido CAPCELL PAC MGIII-C18 column using a gradient elution with acetonitrile and water (0.1% formic acid) as a mobile phase, and the chromatographic separation was 5 min. The methodological evaluation showed that this method had a high sensitivity (the lower limit of quantification was 1 ng/mL for calycosin-7-glucoside, 5 ng/mL for paeoniflorin, 5 ng/mL for amygdalin), satisfactory accuracy (relative error ≤ ±15%) and precision (relative standard deviation ≤15%). Then, the analytical method was applied to the pharmacokinetic study in rats following oral administration of the extracts in QLC. Meanwhile, the pharmacokinetic parameters of complex system in QLC were analyzed and the potential interaction between ingredients was explored. The present quantification method and pharmacokinetic study will provide a meaningful reference for the formulas research of QLC in the treatment of ischemic stroke.

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