bluuebunny/crossref_metadata_2025_split huggingface dataset:
Monitoring the impact of the Jeremenko pit on water quality in Ostravice
Authors: Evjáková V , Pertile E , Kučerová R 
Published: December 2021

Abstract
The study was performed to determine the impact of mine water discharges from the Jeremenko pit on water quality in the Ostravice River. Three sampling points marked under the letters „A”, „B” and „C” were determined for monitoring. The first of the sampling points was designated before the inflow of mine water to determine the parameters of the river before pollution by mine water. Sampling point “B” indicated the inflow of mine water and the last sampling point was used to determine the parameters after mixing mine water with water from the river Ostravice. According to the research, mine water is strongly mineralized with an increased content of salts, chlorides, sulphates and has an increased temperature of up to 28 °C. Based on the analysis of individual results, a significant effect of the inflow of mine water from the Jeremenko pit on the water in the Ostravice River in its immediate vicinity was proved. When compared with the results of other authors, it was found that the concentration of sulfates and chlorides in mine water decreases in the long run.
Handling of railway superstructure material at the end of the life cycle
Authors: Halík M 
Published: December 2021

Abstract
This article deals with the recycling of railway bed aggregates. It briefly describes the methods of handling of the obtained material. It evaluates new possibilities of processing gravel from railway superstructure. It describes the development of the maintenance and reconstruction of railway lines. Furthermore, this article deals with the possibilities of using old materials for new purposes. It presents the results of analyzes of railway aggregate extracts and their comparison with the limit values for deposition on the terrain surface.
The use of glass waste cullet in the concrete production as an important factor in the circular economy
Authors: Junak J , Junakova N 
Published: December 2021

Abstract
The paper focuses on the use of glass waste as a substitute for aggregates (0/4, 4/8 and 8/16 mm) in the production of concrete in order to reduce the negative impact of existing waste on the environment. For the study, 5 mixtures were designed with gradual replacement of individual natural aggregate fractions in the concrete mixture by glass cullet. Real density, total water absorption and compressive strength were monitored on cubes with an edge of 100 mm for a period of 14 days to 3 years. The achieved compressive strength of samples with glass as a filler at the level of 50 MPa gives a good precondition for the real use of such concrete in practice. In addition, when combined it with lower real density and total water absorption.
Surface treatments of recycled brick aggregate and their influence on selected properties of concrete
Authors: Junak J , Sicakova A , Junakova N 
Published: December 2021

Abstract
The paper is devoted to surface treatment of recycled brick aggregate with various impregnating substances in order to reduce its absorbency and verify the use of such treated recycled material as a partial replacement of natural aggregate (fraction 4/8) in concrete. Selected properties of the tested samples were monitored after 28 and 60 days of curing. The results show that the treatment of recycled bricks with water glass appears to be a less suitable alternative compared to the use of a hydrophobic solution of silanes and siloxanes.
Change in dissolved oxygen concentrations during aeration and mixing using a combined system
Authors: Singrova V , Hlustik P 
Published: December 2021

Abstract
Combined mixing and aeration systems are not given priority in the Czech Republic. Still, they are installed at several WWTPs. Their advantage is mixing and aerating at the same time. This article provides data from actual measurements where a combined system was used for drinking water including necessary chemicals. The text below evaluates the course of changes in the concentration of dissolved oxygen in different points in the reactor depending on time.
Changes in thermal stability of lignocelluloses waste aggregates long-term incorporated in composite
Authors: Stevulova N , Estokova A 
Published: December 2021

Abstract
This paper is addressed to comparative study of changes in thermal stability of surface-modified hemp-hurds aggregates long-term incorporated in bio-aggregate-based composites with the original ones before their integration into alternative binder matrix. In this study, the effectiveness of alkaline treatment of hemp hurds compared to the raw bio-aggregates as well as in relation to their behaviour when they are long-term incorporated in the MgO-cement environment is investigated. The differences in the thermal behaviour of the samples are explained by the changed structure of hemp hurds constituents due to the pre-treatment and long-term action of the alternative binder components on the bio-aggregates. Alkaline treatment increases thermal stability of hemp hurds compared to raw sample. Also long-term incorporation of hemp hurds in MgO-cement matrix had a similar effect in case of alkaline modified bio-aggregates. The more alkali ions present in the structure of hemp hurdssamples, the more ash is formed during their thermal decomposition studied by thermal gravimetry (TG) and differential scanning calorimetry (DSC).
Biosorption of chromium by dry algae Chlorella kessleri
Authors: Takáčová A , Bajuszová M , Kohanová J , Lux A , Valent P , Kokavcová A , Takáčová L 
Published: December 2021

Abstract
Decontamination of environment according to traditional methods is not only economically inaccessible but also often highly environmentally harmful. It is necessary to apply methods that are environmentally friendly as possible. These methods include bioremediation, which uses organisms able to fight with high concentrations of pollutants to decontaminate the environment. In this study, we observed the biosorption of chromium from the aquatic environment using dried algae Chlorella kessleri. The results of the specific sorption at pH = 4.00 in the chromium model sample had a value of q = 5.9 mg / g, which represented a decrease in the chromium concentration by 74%. The specific sorption in the case of the native chromium sample q after 24 hours reached the highest value (q = 2.74 mg / g) at pH = 4.00. During the experiment, we observed a constant change in the content of photosynthetic pigments in the prepared solutions where it was shown that after 24 h exposure the yield of chlorophyll a was decrease by 95.91% compare to control. In the case of chlorophyll b, the same trend was demonstrated where 91.92% decrease of its content after 24 hours was observed. This type of dried alga has been shown to be a rapid biosorbent, in relatively short time intervals. The results of the study show that in the process of decontamination there was not only the binding of chromium to the cell surface but also its penetration through the cell wall.
Influence of plasma electrolytic oxidation coating on corrosion characteristics of friction stir welded ZE41 rare earth magnesium alloy
Authors: Sivashanmugam N , Harikrishna K L , Rao S R Koteswara , Rameshbabu N , Manojkumar P 
Published: December 2021

Abstract
Magnesium and its alloys are extensively used in the defence, aerospace and automotive industries, owing to their excellent mechanical properties. But there is a requirement of corrosion prevention treatment before using it for applications, since the corrosion resistance of Mg alloy is poor. In this work, a study on the mechanical properties of friction stir welded ZE41 rare earth magnesium alloy thick plates of 15 mm and 25 mm, was carried out. A metallographic examination and mechanical tests were conducted on both the welds. Furthermore, Plasma Electrolytic Oxidation (PEO), a surface conversion treatment was carried out on both the base material as well as on the friction stir butt joints. X-Ray diffraction and scanning electron microscopy analysis were carried out on all the samples, with and without coating. The coated and uncoated samples were assessed by potentiodynamic polarisation (PDP) tests and electrochemical impedance spectroscopy (EIS) to study the electrochemical corrosion behaviour. An outer porous layer and an inner dense layer, have been identified from the SEM images. From the corrosion tests results it was revealed that there was an improvement in the corrosion resistance of both the base metal as well as the weldments by the PEO coating process.
Magnetic competition in topological kagome magnets
Authors: Thi Tran Thanh-Mai , Nguyen Duong-Bo , Nguyen Hong-Son , Tran Minh-Tien 
Published: December 2021

Abstract
Magnetic competition in topological kagome magnets is studied by incorporating the spin–orbit coupling, anisotropic Hund coupling and spin exchange into a tight-binding electron dynamics in the kagome lattice. Using the Bogoliubov variational principle we find the stable phases at zero and finite temperatures. At zero temperature and in the strong Ising-Hund coupling regime, a magnetic tunability from the out-of-plane ferromagnetism to the in-plane antiferromagnetism is achieved through a universal property of the critical in-plane Hund coupling. At low temperature the out-of-plane ferromagnetism is stable until a finite crossing temperature. Above the crossing temperature the in-plane antiferromagnetism is stable, but the magnetization of the out-of-plane ferromagnetism still survives. This suggests a metastable coexistence of these magnetic phases in a finite temperature range. A large anomalous Hall conductance is observed in the Ising-Hund coupling limit.
Prediction and analysis of thermal aging behavior of magnetorheological grease
Authors: Yang Guangxin , Pan Jiabao , Ye Dongdong , Ye Kaiqiang , Gao Hong 
Published: December 2021

Abstract
Magnetorheological grease (MRG) is a new type of field-response intelligent material with controllable performance and excellent settlement stability, which is feasible to replace traditional materials. The heating phenomenon of magnetorheological (MR) devices is more common during operation and the influence law of continuous thermal effect (thermal aging) on the performance of MRG needs to be studied. In this article, the effect of thermal aging behavior on the rheological properties of MRG has been investigated. Accelerated heat treat the sample and test the shear stress under the condition of thermo-magnetic coupling. To reduce the time and cost during the study of MR materials, an improved and reliable artificial neural network (ANN) prediction model was developed to characterize and predict the relationship among temperature, aging time, magnetic field strength and the thermo-rheological properties of MRG. The test results of MRG before and after thermal aging show that thermal aging causes irreversible structural damage and the performance decreases with increasing aging time. The comparison of the ANN prediction results with the test results, the correlation coefficient R reached and exceeded 0.95. The results showed that the model had excellent prediction accuracy and could provide theoretical reference for the thermal aging behavior of MRG.
Comparative studies on the morphological, structural and optical properties of NiO thin films grown by vacuum and non-vacuum deposition techniques
Authors: Jamal M S , Chowdhury M S , Bajgai Saraswati , Hossain M , Laref A , Jha Pankaj Kumar , Techato Kuaanan 
Published: December 2021

Abstract
The structural and optical characteristics of Nickel oxide thin films (NiOTF) formed on the soda-lime glass substrate (SLG) under vacuum and non-vacuum conditions are investigated in this work. The difference between RFMS (Radio Frequency Magnetron Sputtering; vacuum) and SP (spray pyrolysis; non-vacuum) was helpful in the development of NiOTF. Deposited films data for this study were characterized by using x-ray diffraction (XRD), field emission scanning electron microscopy (FESEM), scanning probe microscopy (SPM), and optical spectrophotometer. Structural studies disclosed that NiOTF developed via RFMS technique was more uniform with large crystals and lower surface roughness in contrast to that of developed via SP technique. Transmittance spectrum divulged that the transmittance of spray pyrolyzed NiO films are ∼10% less than that of ones produced by RFMS. Urbach energy analysis of NiOTF developed by RFMS and SP affirmed the findings of structural studies.
MiR-290 family maintains developmental potential by targeting p21 in mouse preimplantation embryos
Authors: Li Xiangnan , Liu Yueshi , Mu Qier , Tian Junliang , Yu Haiquan 
Published: December 2021

Abstract
The miR-290 family is a mouse-specific microRNA cluster, which maintains mouse embryonic stem cells (ESCs) pluripotency by increasing OCT3/4 and C-MYC expression. However, its functions in mouse preimplantation embryos remain unclear, especially during zygotic genome activation (ZGA). In this study, miR-290 family expression increased from the two-cell embryo stage through the blastocyst stage. Inhibition of miR-294-3p/5p did not affect ZGA initiation or embryo development, whereas pri-miR-290 knockdown decreased ZGA gene expression and slowed embryonic development. In addition, pluripotency decreased in ESCs derived from pri-miR-290 knockdown blastocysts. To clarify the mechanism of action, 33 candidate miR-294-3p target genes were screened from three databases, and miR-294-3p directly targeted the 3′-untranslated region of Cdkn1a (p21) mRNA. Similar to pri-miR-290 knockdown, P21 overexpression impeded embryonic development, whereas simultaneous overexpression of P21 and pri-miR-290 partially rescued embryonic development. The results indicate that the miR-290 family participates in promoting ZGA process and maintaining developmental potency in embryos by targeting p21.
Ultrasound delivery of a TrkA agonist confers neuroprotection to Alzheimer-associated pathologies
Authors: Xhima Kristiana , Markham-Coultes Kelly , Hahn Kofoed Rikke , Saragovi H Uri , Hynynen Kullervo , Aubert Isabelle 
Published: December 2021

Abstract
Early degeneration of basal forebrain cholinergic neurons contributes substantially to cognitive decline in Alzheimer’s disease. Evidence from preclinical models of neuronal injury and aging support a pivotal role for nerve growth factor (NGF) in neuroprotection, resilience, and cognitive function. However, whether NGF can provide therapeutic benefit in the presence of Alzheimer’s disease-related pathologies still unresolved. Perturbations in the NGF signalling system in Alzheimer’s disease may render neurons unable to benefit from NGF administration. Additionally, challenges related to brain delivery remain for clinical translation of NGF-based therapies in Alzheimer’s disease. To be safe and efficient, NGF-related agents should stimulate the NGF receptor, tropomyosin receptor kinase A (TrkA), avoid activation through the p75 neurotrophin receptor (p75NTR), and be delivered non-invasively to targeted brain areas using real-time monitoring. We addressed these limitations using MRI-guided focused ultrasound (MRIgFUS) to increase blood–brain barrier permeability locally and transiently, allowing an intravenously administered TrkA agonist that does not activate p75NTR, termed D3, to enter targeted brain areas. Here, we report the therapeutic potential of selective TrkA activation in a transgenic mouse model that recapitulates numerous Alzheimer’s disease-associated pathologies. Repeated MRIgFUS-mediated delivery of D3 (D3/FUS) improved cognitive function in the TgCRND8 model of Alzheimer’s disease. Mechanistically, D3/FUS treatment effectively attenuated cholinergic degeneration and promoted functional recovery. D3/FUS treatment also resulted in widespread reduction of brain amyloid pathology and dystrophic neurites surrounding amyloid plaques. Furthermore, D3/FUS markedly enhanced hippocampal neurogenesis in TgCRND8 mice, implicating TrkA agonism as a novel therapeutic target to promote neurogenesis in the context of Alzheimer’s disease-related pathology. Thus, this study provides evidence that selective TrkA agonism confers neuroprotection to effectively counteract Alzheimer’s disease-related vulnerability. Recent clinical trials demonstrate that non-invasive blood–brain barrier modulation using MRIgFUS is safe, feasible and reversible in Alzheimer’s disease patients. TrkA receptor agonists coupled with MRIgFUS delivery constitute a promising disease-modifying strategy to foster brain health and counteract cognitive decline in Alzheimer’s disease.
Neutralization of Severe Acute Respiratory Syndrome Coronavirus 2 Omicron Variant by Sera From BNT162b2 or CoronaVac Vaccine Recipients
Authors: Lu Lu , Mok Bobo Wing Yee , Chen Lin Lei , Chan Jacky Man Chun , Tsang Owen Tak Yin , Lam Bosco Hoi Shiu , Chuang Vivien Wai Man , Chu Allen Wing Ho , Chan Wan Mui , Ip Jonathan Daniel , Chan Brian Pui Chun , Zhang Ruiqi , Yip Cyril Chik Yan , Cheng Vincent Chi Chung , Chan Kwok Hung , Jin Dong Yan , Hung Ivan Fan Ngai , Yuen Kwok Yung , Chen Honglin , To Kelvin Kai Wang 
Published: December 2021

Abstract

Background
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) omicron variant, designated as a variant of concern by the World Health Organization, carries numerous spike mutations that are known to evade neutralizing antibodies elicited by coronavirus disease 2019 (COVID-19) vaccines. A deeper understanding of the susceptibility of omicron variant to vaccine-induced neutralizing antibodies is urgently needed for risk assessment.

Methods
Omicron variant strains HKU691 and HKU344-R346K were isolated from patients using TMPRSS2-overexpressing VeroE6 cells. Whole genome sequence was determined using nanopore sequencing. Neutralization susceptibility of ancestral lineage A virus and the omicron, delta and beta variants to sera from 25 BNT162b2 and 25 CoronaVac vaccine recipients was determined using a live virus microneutralization assay.

Results
The omicron variant strain HKU344-R346K has an additional spike R346K mutation, which is present in 8.5% of strains deposited in the GISAID database. Only 20% and 24% of BNT162b2 recipients had detectable neutralizing antibody against the omicron variant HKU691 and HKU344-R346K, respectively, whereas none of the CoronaVac recipients had detectable neutralizing antibody titer against either omicron isolate. For BNT162b2 recipients, the geometric mean neutralization antibody titers (GMTs) of the omicron variant isolates (5.43 and 6.42) were 35.7–39.9-fold lower than that of the ancestral virus (229.4), and the GMTs of both omicron variant isolates were significantly lower than those of the beta and delta variants. There was no significant difference in the GMTs between HKU691 and HKU344-R346K.

Conclusions
Omicron variant escapes neutralizing antibodies elicited by BNT162b2 or CoronaVac. The additional R346K mutation did not affect the neutralization susceptibility. Our data suggest that the omicron variant may be associated with lower COVID-19 vaccine effectiveness.
del Nido cardioplegia better preserves cardiac diastolic function but histidine–tryptophan–ketoglutarate is better for endothelial function
Authors: Xue Hong-Mei , Hou Hai-Tao , Sun Wen-Tao , Wang Shi-Fu , Guo Shan , Yang Qin , He Guo-Wei 
Published: December 2021

AbstractOBJECTIVESThe effectiveness of myocardial protection of cardioplegia has been a matter of debate for decades. This study was designed to compare cardiac and endothelial protection of 3 clinically used cardioplegias: del Nido cardioplegia (DNC), histidine–tryptophan–ketoglutarate (HTK) and blood cardioplegia (BC) followed by HTK (BC + HTK) in a rat model of ischaemia/reperfusion (I/R).METHODSSixty male Wistar rats were subjected to either 120 min of global ischaemia at 4°C followed by 90 min of reperfusion (I/R) at 37°C or no I/R (control) in a Langendorff apparatus and were randomly allocated to 5 groups: control, I/R, DNC, HTK and BC + HTK. Cold cardioplegia solutions were administered at doses of 20 ml/kg for DNC and HTK or 10 ml/kg for BC followed by HTK. Haemodynamic parameters were continuously recorded using an intraventricular balloon. The endothelium-dependent relaxation to acetylcholine was measured in the left anterior descending artery using a myograph. Protein expression of cardiac troponin T (cTnT) and creatine kinase MB was determined by western blot.RESULTSDuring reperfusion, HTK had higher left ventricular systolic pressure whereas DNC had lower left ventricular end-diastolic pressure, better left ventricular developed pressure and best +dp/dtmax and −dp/dtmax than the other 2 groups but the differences disappeared at the end of the reperfusion. HTK or BC + HTK preserves the acetylcholine-induced endothelium-dependent relaxation better than DNC (Emax = 48.2 ± 8.0% in DNC vs 75.0 ± 8.0% in HTK, P &lt; 0.05; vs 96.9 ± 3.5% in BC + HTK, P &lt; 0.001). The protein levels of cTnT and creatine kinase MB were downregulated in the 3 groups.CONCLUSIONSAll 3 cardioplegias prevented myocardial damage against I/R injury at the end of reperfusion. DNC demonstrated better preserved diastolic function of the left ventricle whereas HTK or BC + HTK showed better preserved coronary endothelial function. These findings may suggest that currently no ‘perfect’ cardioplegia exists and that exploration for the ‘perfect’ cardioplegia is needed.
Infrared thoracoscopic pulmonary segmentectomy with intravenous indocyanine green administration using preoperative simulation
Authors: Igai Hitoshi , Matsuura Natsumi , Kamiyoshihara Mitsuhiro 
Published: December 2021

Abstract
Infrared thoracoscopy with intravenous indocyanine green administration is one of the useful methods to identify an appropriate intersegmental line during thoracoscopic pulmonary segmentectomy. In this procedure, we have introduced preoperative simulation to calculate the distance between the target tumour and intersegmental plane using Ziostation2 (Ziosoft, Tokyo, Japan) to ensure sufficient surgical margin without palpation. By using this preoperative simulation, we obtained sufficient surgical margin in a patient with a 16-mm part-solid nodular shadow undergoing infrared thoracoscopic upper division (S1–3) segmentectomy of left upper lobe with intravenous indocyanine green administration. The discrepancy between the virtual and the actual surgical margin was &lt;10 mm. This preoperative simulation can help us obtain sufficient surgical margin without palpation of the tumour in infrared thoracoscopic segmentectomy.