bluuebunny/crossref_metadata_2025_split huggingface dataset:
Structure‐Property Correlation of C10‐(H)‐Arylated‐N‐(pyren‐1‐yl)‐picolinamide Regioisomers towards Cu2+ and Fe3+ Sensing
Authors: Reji Rosmi , Tripathi Narendra Pratap , Rani Kavita , Dalal Arup , Babu Srinivasarao Arulananda , Sengupta Sanchita 
Published: November 2021

AbstractRecently developed C10‐(H)‐arylated‐N‐(pyren‐1yl)‐picolinamide compounds have been investigated spectroscopically for their photophysical properties and metal ion sensing abilities. Two sets of regioisomers were selected based on their molar absorptivities and fluorescence quantum yields and classified into two series I methoxy group at meta‐ and para‐ position of phenyl ring, and series II methyl group at meta‐ and para‐ position of phenyl ring. Additionally, for better understanding on structure‐property relationship, a comparison study with C‐10 unsubstituted compound was also conducted. All compounds exhibited characteristic absorption and emission responses only towards Cu2+ and Fe3+ ions among all the screened metals. While the reference compound and those with methoxy substituent displayed a fluorescence turn‐off behaviour, compounds with methyl groups showed fluorescence turn‐on response through excimer formation at ∼550 nm in the presence of Cu2+ and Fe3+. Sensing studies were performed to elucidate structure‐property relationship and to obtain limits of detection, binding constants and fluorescence quenching constants. Temperature‐dependent fluorescence studies were performed to distinguish the type of excimers produced by two compounds in series II with the metal ions.
Spatiotemporal hydrological analysis of streamflows and groundwater recharge for sustainable water management in Prince Edward Island, Canada
Authors: Bhatti Ahmad Zeeshan , Farooque Aitazaz Ahsan , Krouglicof Nicholas , Peters Wayne , Acharya Bishnu , Li Qing , Ahsan Muhammad Sheraz 
Published: November 2021

AbstractPrince Edward Island (PEI), Canada, entirely depends on groundwater for freshwater supplies, which also highly feeds streamflows. In a few watersheds, pumping has had disturbed steady‐state conditions and reduced streamflows. Spatiotemporal hydrological analysis of streamflows and recharges was performed in its scattered watersheds. Mill, Wilmot, West, Winter, and Bear River watersheds were modeled by the Soil and Water Assessment Tool (SWAT) under the shallow water‐table conditions, besides other analyses. The model was calibrated against 120 observed mean monthly flows (1995–2004) and validated for another 120 observations (2005–2014), with Nash–Sutcliffe efficiency (NSE) as the major performance assessment parameter. The model accurately simulated mean monthly flows for all watersheds during 1995–2014, except Winter River watershed (NSE = 0.02–0.33), wherein it overpredicted by 31%–52% and 5–12% in Wilmot River (NSE = 0.28–0.64). Streamflows were found highly dependent on groundwater; therefore, pumpings of 6.92 and 0.73 million cubic meters (MCM)/year caused the overpredictions in Winter and Wilmot watersheds, as SWAT cannot account pumping. In the rest three watersheds with negligible pumping, 4%–18% underprediction was due to multisite calibration. Spatially, streamflows randomly varied between 555 and 811 mm/year across watersheds, whereas thick and highly permeable sandstone produced higher recharges, the maximum ~600 mm/year in the eastern forest‐dominated Bear River watershed, lesser in western ~330 mm/year, and moderate ~450 mm/year in central watersheds. Temporally, March–May are the months of highest streamflows, whereas recharge is maximum during April–July. The succession trend justified strong surface water–groundwater interactions. Existing Water Extraction Permitting Policy ensures sustainability at the island scale. It sets pumping limit at 20% of recharge, that is, 0.48 km3/year altogether, against the present pumping of ~0.04 km3/year, yet a few watersheds are somewhat water‐stressed due to population and pumping concentration. Expansion of streamflow and groundwater monitoring, promoting population and pumping in rural areas, and more scrutiny for further pumping permits in water‐stressed watersheds are quite important for sustainable water management in PEI.
Mentorship, Sponsorship, and Professional Networking
Authors: Jamison-McClung Denneal 
Published: November 2021

AbstractCreating an ecosystem of mentorship and sponsorship requires institutional commitment and the collaboration of faculty and administrators from diverse backgrounds. From 2012 to 2018, the UC Davis ADVANCE Mentorship and Networking Initiative (MNI) partnered with the campus leadership to implement several programs and activities to support mentorship, sponsorship, and professional networking for STEM women faculty across career levels. During this award period, pilot programs aimed to provide strong mentorship for newly recruited faculty, including scholars affiliated with the Center for Multicultural Perspectives on Science (CAMPOS) as well as mid-career faculty, with the intention of scaling efforts across campus units. MNI committee projects included piloting “Launch Mentoring Committees” for 43 new faculty, support for faculty-led “New Faculty Network” monthly networking mixers, implementation of the Associate Professor Network listserv, annual co-hosting of the Fall Welcome for Women Faculty, and development of the ADVANCE Scholar Award Distinguished Lecture and Networking Reception. Though all MNI programs and activities were well-received, both faculty mentors and mentees evaluated the Launch Mentoring Committees especially positively. This program emerged as a recommended best practice for engaging new faculty and building a sense of community that crosses disciplinary and intersectional boundaries.
Latinx Communities and Academic Trajectories
Authors: Brazil-Cruz Lisceth , Grindstaff Laura , Flores Yvette G. 
Published: November 2021

AbstractThis chapter will focus on why the Latina experience is critical to understanding current efforts to diversify the academy in the United States. We discuss the demographic realities of Latinx representation in higher education, the various ways in which Latinx scholars are marginalized, and what’s currently known about “best practices” when seeking excellence and inclusion through institutional diversity. We stress the importance of intersectionality in understanding and addressing the underrepresentation of Latina scholars in STEM.
Seeing Self: The CAMPOS Model
Authors: de Leon Siantz Mary Lou , Brazil-Cruz Lisceth 
Published: November 2021

AbstractBuilding an inclusive community that diversifies the fields of science, technology, engineering, and mathematics (STEM) is a daunting task, all the more so given the low numbers of Latinas and other underrepresented minority groups (URM) who enter academic STEM disciplines. This chapter takes an in-depth look at one of the novel ADVANCE initiatives—the Center for the Advancement of Multicultural Perspectives on Science (CAMPOS). The center fosters sustainable institutional transformation by collaborating with traditional campus committees to recruit, retain, and promote excellent faculty committed to inclusion while also engaging the broader UC Davis STEM community. Its core mission is to support the discovery of knowledge though multicultural perspectives. CAMPOS creates an environment that is diversity-driven, mentorship-grounded, and career-success-focused. It recognizes the barriers that URM STEM scientists endure within academia and seeks to mitigate those barriers, highlighting the accomplishments of CAMPOS faculty scholars and making URM STEM scientists visible role models. The center is committed to transforming STEM by developing the leadership skills needed to sustain institutional transformation in laboratories, departments, and universities locally, nationally, and globally. The CAMPOS model can be replicated at other universities seeking to change the face of STEM.
Comparison of Aspiration Catheters with Modified Standard Catheters for Treatment of Large Pulmonary Embolism Using an In-vitro Patho-Physiological Model
Authors: Schubert Franziska , Tamura Masashi , Bezela Sophie , Weyers Alexander , Kütting Daniel , Menne Matthias , Steinseifer Ulrich , Clauser Johanna C. , Schmitz-Rode Thomas 
Published: November 2021

Abstract
Purpose
The presented in-vitro study provides a comparison of various catheters for mechanical treatment of large-burden pulmonary embolism (PE) under standardized conditions, using a new test rig. Dedicated aspiration catheters (JETi®, Penumbra Indigo®, Aspirex®) were compared with standard catheters (Pigtail, Multi-Purpose, Balloon Catheter) applied for embolus fragmentation.

Materials and Methods
Emboli prepared from porcine blood were washed into the test rig which consists of anatomical models of the pulmonary artery (PA) and of the right heart in combination with a pulsatile drive system. For all catheters, the duration of the recanalization procedure and the weight percentage (wt%) of the remaining, removed and washed-down clot fractions were evaluated. For aspiration catheters, the aspirated volume was measured.

Results
All catheters achieved full or partial recanalization. The aspiration catheters showed a significantly (p < 0.05) lower procedure time (3:15 min ± 4:26 min) than the standard fragmentation catheters (7:19 min ± 4:40 min). The amount of thrombus removed by aspiration was significantly (p < 0.001) higher than that by fragmentation, averaging 86.1 wt% ± 15.6 wt% and 31.7 wt% ± 3.8 wt%, respectively. Nonetheless, most of the residue was fragmented into pieces of ≥ 1 mm and washed down. Only in 2 of 36 tests, a residual thrombus of 11.9 wt% ± 5.1 wt% remained in the central PA.

Conclusion
Comparison under standardized in-vitro patho-physiological conditions showed that embolus fragmentation with standard catheters is clearly inferior to aspiration with dedicated catheters in the treatment of large-burden PE, but can still achieve considerable success.

Level of Evidence
No level of evidence, experimental study.
Convection-permitting fully coupled WRF-Hydro ensemble simulations in high mountain environment: impact of boundary layer- and lateral flow parameterizations on land–atmosphere interactions
Authors: Zhang Zhenyu , Arnault Joel , Laux Patrick , Ma Ning , Wei Jianhui , Shang Shasha , Kunstmann Harald 
Published: November 2021

AbstractNumerical climate models have been upgraded by the improved description of terrestrial hydrological processes across different scales. The goal of this study is to explore the role of terrestrial hydrological processes on land–atmosphere interactions within the context of modeling uncertainties related to model physics parameterization. The models applied are the Weather Research and Forecasting (WRF) model and its coupled hydrological modeling system WRF-Hydro, which depicts the lateral terrestrial hydrological processes and further allows their feedback to the atmosphere. We conducted convection-permitting simulations (3 km) over the Heihe River Basin in Northwest China for the period 2008–2010, and particularly focused on its upper reach area of complex high mountains. In order to account for the modeling uncertainties associated with model physics parameterization, an ensemble of simulations is generated by varying the planetary boundary layer (PBL) schemes. We embedded the fully three-dimensional atmospheric water tagging method in both WRF and WRF-Hydro for quantifying the strength of land–atmosphere interactions. The impact of PBL parameterization on land–atmosphere interactions is evaluated through its direct effect on vertical mixing. Results suggest that enabled lateral terrestrial flow in WRF-Hydro distinctly increases soil moisture and evapotranspiration near the surface in the high mountains, thereby modifies the atmospheric condition regardless of the applied PBL scheme. The local precipitation recycling ratio in the study area increases from 1.52 to 1.9% due to the description of lateral terrestrial flow, and such positive feedback processes are irrespective of the modeling variability caused by PBL parameterizations. This study highlights the non-negligible contribution of lateral terrestrial flow to local precipitation recycling, indicating the potential of the fully coupled modeling in land–atmosphere interactions research.
Including dental professionals in the multidisciplinary treatment team of head and neck cancer patients improves long-term oral health status
Authors: Bertl Kristina , Savvidis Philippe , Kukla Edmund Benjamin , Schneider Steffen , Zauza Konstantin , Bruckmann Corinna , Stavropoulos Andreas 
Published: November 2021

Abstract
Objective
To assess in a cross-sectional study the impact of including dental professionals in the multidisciplinary treatment team of head and neck squamous cell carcinoma (HNSCC) patients on the long-term oral health status.

Materials and methods
Oral health status, dental care behaviours, and oral health–related quality of life were assessed based on a clinical and radiographic examination, interview, and medical records in patients treated for HNSCC ≥ 6 months ago. This patient group (‘cohort 2’) was treated in a multidisciplinary treatment team including dental professionals and compared to a group of HNSCC patients previously treated at the same university, but without dental professionals included in the multidisciplinary treatment team (‘cohort 1’).

Results
Cohort 2 consisted of 34 patients, who had received a dental check-up and if necessary, treatment by dental professionals prior to the initiation of cancer treatment. This cohort showed significantly improved oral hygiene habits and a better periodontal health status compared to cohort 1. However, cohort 2 still presented high demand for treatment due to active carious lesions; only a few, statistically insignificant improvements were detected compared to cohort 1.

Conclusion
Including dental professionals in the multidisciplinary treatment team of HNSCC patients has a positive impact on patient oral health status—primarily in terms of periodontal disease—6 months and longer after finishing cancer therapy.

Clinical relevance
A team-based approach including dental professionals specialised in head and neck cancer improves oral health status.
Comparative study of high-pressure fluid flow in densely packed granules using a 3D CFD model in a continuous medium and a simplified 2D DEM-CFD approach
Authors: Abdi R. , Krzaczek M. , Tejchman J. 
Published: November 2021

AbstractAn isothermal compressible single-phase fluid flow through a non-homogeneous granular body composed of densely packed overlapping spheres imitating rock under high pressure was numerically studied using two different approaches. The first approach called the full 3D CFD model used the finite volume method (FVM) to solve the Reynolds-averaged Navier–Stokes equations using Reynolds stress model (BSL) in the continuous domain between the granulates. The model was verified, based on experimental and numerical results from the literature. The second approach was a simplified coupled DEM-CFD model based on a fluid flow network. The main aim of the work was to develop a validation procedure for simplified coupled DEM-CFD models due to the lack of experimental data for fluid flow characteristics in densely packed granules under extremely high-pressure conditions. First, a series of numerical simulations were performed for the fluid domain with the full 3D CFD model. The results of those simulations were next used to validate the 2D numerical results of the simplified coupled DEM-CFD model with respect to velocities, pressures, densities and flow rates. Almost the same pressure and density distributions and mass flow rates were obtained in both approaches. However, the fluid velocity was different due to the different fluid volumes in both fluid domains. The current simulation results constitute a reliable benchmark for validating other coupled 2D/3D DEM-CFD models that use a fluid flow network approach.
Graphic abstract
Plasma exchange with albumin replacement and disease progression in amyotrophic lateral sclerosis: a pilot study
Authors: Povedano Mónica , Paipa Andrés , Barceló Miquel , Woodward Michael K. , Ortega Sandra , Domínguez Raúl , Aragonés Maria Esperança , Horrillo Raquel , Costa Montserrat , Páez Antonio 
Published: November 2021

Abstract
Background
Plasma exchange (PE) is used to treat a range of neurological disorders. Based on results demonstrated in Alzheimer’s disease, we theorized that PE with albumin replacement (PE-A) might alter the metabolic profile of plasma and cerebrospinal fluid in patients with amyotrophic lateral sclerosis (ALS) by removing disease-inducing molecules. The aim of this study was to evaluate the effect of PE-A on disease progression in ALS.

Methods
In this open-label, non-controlled, single-arm, prospective pilot study, 13 adults with ALS had 6 months’ treatment with PE-A 5% and 6 months’ follow-up. Primary endpoints were changes from baseline in the Amyotrophic Lateral Sclerosis Functional Rating Scale-Revised (ALSFRS-R) score and forced vital capacity (FVC) through 48 weeks. A post hoc analysis compared individual patient data with the expected ALSFRS-R progression slope.

Results
The median ALSFRS-R score declined throughout the study, although the rate of decline was slower than expected in seven patients at treatment end and in five patients at study end. Six patients remained in the same baseline slope progression category, and four patients improved their slope category at treatment end. Median FVC decreased significantly during the study. Treatment was well tolerated. Of 330 PE-A procedures, 0.9% were associated with potentially related adverse events.

Conclusion
Although functional impairment progressed, about two-thirds of patients showed a slower than expected rate of decline at treatment end. Most patients had unaltered (54.5%) or reduced (36.4%) ALSFRS-R slope progression at treatment end. Further evaluation of PE-A in controlled studies involving more patients is warranted.

EudraCT number
2013-004842-40.

Trial registration
ClinicalTrials.gov identifier: NCT02479802.
Analysis of the diagnostic accuracy of rapid antigenic tests for detection of SARS-CoV-2 in hospital outbreak situation
Authors: Aranaz-Andrés Jesús María , Chávez Abelardo Claudio Fernández , Laso Amaranta McGee , Abreu Melanie , Núñez Paloma Moreno , Galán Juan Carlos , Moreno Rafael Cantón 
Published: November 2021

Abstract

The reverse transcriptase polymerase chain reaction (RT-PCR) continues to be the reference diagnostic method for the confirmation of COVID-19 cases; however, rapid antigen detection tests (RADT) have recently been developed. The purpose of the study is to assess the performance of rapid antigen-based COVID-19 testing in the context of hospital outbreaks. This was an observational, cross-sectional study. The study period was from October 2020 to January 2021. The “Panbio COVID-19 AG” RADT (Abbott) was performed and TaqPath COVID-19 test RT-PCR. The samples were obtained from hospitalised patients in suspected outbreak situations at the Ramón y Cajal Hospital. A hospital outbreak was defined as the presence of 3 or more epidemiologically linked cases. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of the RADT were calculated using RT-PCR as a reference. A total of 17 hospital outbreaks were detected in 11 hospital units during the study period, in which 34 RT-PCR and RADT screenings were performed. We obtained 541 samples, which were analysed with RT-PCR and a further 541 analysed with RADT. Six RADT tests gave conflicting results with the RT-PCR, 5 of them with a negative RADT and positive RT-PCR and one with positive RADT and a negative RT-PCR. The sensitivity of the RADT was 83.3% (65.3–94.4%) and the specificity was 99.8% (98.9–100%). The PPV was 96.2% (80.4–99.9%) and the NPV was 99% (97.7–99.7%). The RADT shows good diagnostic performance in patients on non-COVID-19 hospital wards, in the context of an outbreak.
Glasfaserbereitstellungsentgelt — wirksames Instrument für rascheren Gigabitausbau?
Authors: Gerpott Torsten J. 
Published: November 2021

ZusammenfassungDas Telekommunikationsmodernisierungsgesetz führt ab dem 1. Dezember 2021 mit § 72 Telekommunikationsgesetz ein „Glasfaserbereitstellungsentgelt“ für gebäudeinterne Netze befristet ein. Die neue Vorschrift wird erläutert. Sie sollte in eine Richtung weiterentwickelt werden, die Interessen von Mieter:innen, Immobilienunternehmen, Vermieter:innen und Festnetzbetreibenden ausgewogener berücksichtigt. Außerdem sollten stärkere Beschleunigungsimpulse beim Bau von Glasfaseranschlüssen gesetzt werden.
Gender gap in the impact of social capital on household food security in Zimbabwe: does spatial proximity matter?
Authors: Kairiza Terrence , Kembo George , Magadzire Vengesai , Chigusiwa Lloyd 
Published: November 2021

AbstractDespite the numerous strides that have been made towards ensuring food security since the launch of the United Nations Millennium Development Goals (MDGs), the gap between the rich and poor across and within countries is still worryingly too large. Around 57.7% of the Sub-Saharan Africa (SSA) population is food insecure compared to 26.4% of the world population. It is therefore necessary to make concerted efforts to improve food security in Sub-Saharan Africa and the rest of the developing world particularly among the poorest and most vulnerable groups. This paper employs propensity score matching analysis to explore gender heterogeneity in the impact of bonding and bridging social capital on household food security on the basis of a nationally representative sample of Zimbabwean households. It offers five major findings. First, female headed households are more likely to have bonding social capital than their male counterparts. Second, there are no gender differences in the household’s ability to possess bridging social capital. Third, household spatial proximity to households with social capital improves the probability of the household possessing social capital. Fourth, both bonding and bridging social capital improves household food security. Finally, female headed households are more able to increase food security than those headed by males when they have both bonding and bridging social capital. The study argues that coping strategies should target putting the family at the core of inclusive development agendas such as food and nutrition assistance programmes in order to maximise the likelihood of easing food insecurity within communities.
Lost in uncertainty? Sozial entscheiden und organisieren in der Sozialwirtschaft
Authors: Effinger Herbert 
Published: November 2021

ZusammenfassungDieser Beitrag der Zeitschrift „Gruppe. Interaktion. Organisation. (GIO)“ behandelt den Wohlfahrtsmix von Gemeinschaft, Sozialstaat und Markt mit ihren widersprüchlichen Regulationsprinzipien in der Sozialwirtschaft. Im Zusammenspiel solidarischer, sozialstaatlicher und ökonomischer Regulation werden Situationen von Ungewissheit, Ambiguität, Unsicherheit und Ambivalenz sowie wenig geeignete Bewältigungsstrategien, wie ein defensives Vermeidungsverhalten und dysfunktionale Organisationskulturen, begünstigt. In dem Kontext stehen die Organisationen und ihre Sorgearbeitenden vor der Herausforderung Komplexität und damit verbundener Ungewissheit und Unsicherheit bewältigen zu müssen und sich dabei vor unproduktiven Komplexitätsreduktionen, etwa in Form von moralisierender Vereindeutigungen und Simplifizierungen, zu schützen. Es gilt die widersprüchlichen Dynamiken dieses Handlungsfeldes proaktiv zu auszubalancieren und zu bewältigen.