bluuebunny/crossref_metadata_2025_split huggingface dataset:
Machseh Lajesoumim
Authors: Focke Jaap 
Published: September 2021

The Jewish Orphanage in Leiden was the last one of eight such care homes to open its doors in the Netherlands before the Second World War. After spending almost 39 years in an old and utterly inadequate building in Leiden's city centre, the inauguration in 1929 of a brand-new building, shown on the front cover, was the start of a remarkably productive and prosperous period.
The building still stands there, proudly but sadly, to this day: the relatively happy period lasted less than fourteen years. On Wednesday evening, 17th March 1943, the Leiden police, under German instructions, closed down the orphanage and delivered 50 children and nine staff to the Leiden railway station, from where they were brought to Transit Camp Westerbork in the north-east of the country. Two boys were released from Westerbork thanks to tireless efforts of a neighbour in Leiden; one young woman survived Auschwitz, and one young girl escaped to Palestine via Bergen-Belsen. The remaining 55 were deported to Sobibor – and not one of them survived.
Some 168 children lived in the new building at one time or another between August 1929 and March 1943. This book reconstructs life in the orphanage based on the many stories and photographs which they left us. It is dedicated to the memory of those who perished in the Holocaust, but also to those who survived. Without them, this book could not have been written.
Intellektuális képességzavart mutató személyek jogainak támogatását befolyásoló tényezők
Authors: Horváth Sára , Hadarics Márton 
Published: September 2021

Háttér és célok: Kutatásunkban a Fogyatékossággal élő személyek jogairól szóló ENSZ Egyezmény alapján az intellektuális képességzavart mutató személyek számára biztosítandó jogokkal (lakáskörülmények megválasztása, házasságkötés, munkavállalás, integrált oktatás, gyermekvállalás, örökbefogadás, politikai részvétel) kapcsolatos attitűdöket vizsgáltuk. Arra kerestük a választ, hogy fellelhető-e együttjárás az egyes jogok között, illetve milyen szociálpszichológiai konstruktumok lehetnek a jogok elutasításának hátterében.
Módszer: A szociális dominancia orientáció (SDO), a jobboldali tekintélyelvűség (RWA), illetve a sajnálat csoportközi érzelmének hatását vizsgáltuk online kérdőíves módszerrel.
Eredmények: A jogok együttjárását feltáró faktoranalízissel vizsgáltuk, mely során két faktor rajzolódott ki, az elsőbe a nagyobb támogatottságot élvező, inkább szorosan az intellektuális képességzavart mutató személyt érintő, míg a másodikba a kevésbé támogatott, a többségi társadalomra nagyobb hatást gyakorló jogok tartoztak. A lineáris regresszió alapján az SDO és az RWA (részben) szignifikáns összefüggést mutatott a jogok elutasításával. Érdekes jelenséget mutatott a sajnálat csoportközi érzelmének beemelése, mely további vizsgálatot igényel.
Következtetések: A kutatás eredményei hasznos kiindulópontot adhatnak, hogy jobban megértsük, milyen folyamatok állnak az IKZ-t mutató emberek társadalmi részvételének elutasítása mögött. A kapott információk segíthetnek az IKZ-t mutató személyek inklúzióját támogató szemléletformáló programok javításában.
Kulcsszavak: SDO, RWA, intellektuális képességzavar, sajnálat, jogok
Érintéstől a tanításig
Authors: Bernolák Dóra , Imrik Eszter 
Published: September 2021

Írásunkban az értelmileg akadályozottak pedagógiája szakirányos gyógypedagógus hallgatók intézményünkben, az ELTE Gyakorló Óvoda és EGYMI-ben folyó szakmai gyakorlatának szervezési és tartalmi kereteibe szeretnénk betekintést nyújtani. A pályaszocializáció egyik fontos állomása a szakmai képzés, melynek egyik pillére a gyakorlati ismeretek megszerzése. A hallgatók szakpedagógiai és terepgyakorlata zajlik intézményünkben a korai fejlesztés és az óvodai nevelés színterén. Jelen írásunk fókuszában az ezen a területen szerzett gyakorlatvezetői tapasztalataink megosztása áll. Bemutatásra kerül az intézményi eljárásrend, a szervezési keretek és az ezekhez kapcsolódó tapasztalatok. Megosztjuk az adott színtéren szerzett gyakorlatvezetői tapasztalatainkat, a helyzetben rejlő kihívásokat és fejlődési lehetőségeket. Kitérünk a járványhelyzet során kipróbált gyakorlatvezetési lehetőségekre, összegezzük a hallgatói gyakorlatok során tapasztalt hangsúlyos kérdéseket.
Kulcsszavak: pályaszocializáció, intézményi protokoll, gyakorlatvezetői meglátások, reflektivitás, önismeret
Commentary: Does Twitter have a role in Family Planning in Low-and-Middle-Income Countries (LMICs)?
Authors: Harrison Denise , Ramarao Saumya , Vijeyakumar Dinesh , McKinnon James , Brown Kristina , Mierzwa Stanley John 
Published: September 2021

Stakeholders are coming together to develop a vision for increasing access to family planning (FP) by 2030. Of the 923 million women in the developing world who wish to avoid a pregnancy, 218 million women are not using a modern contraceptive (Guttmacher Institute, 2020). In 2016, over 3.4 billion people were using the internet (https://ourworldindata.org/internet 2016). Moreover, internet users in the developing world use social media more frequently than Internet users in the U.S. and Europe. Of the many proposed actions to accelerate progress in family planning, the use of Twitter should be a key component.

In this commentary, we describe the use of Twitter in a select group of low-and-middle-income countries that have made commitments to the family planning 2020 initiative (FP2020 countries, and have the potential to leverage Twitter with current and potential family planning users. We examine Twitter feeds in eight key FP2020 countries, and we look at the content of Tweets issued by the ministries of health in most of these same countries.

Our view is that it is feasible and easy to access Twitter feeds in low and middle income countries. We base our view on the types of reproductive health and family planning terms discussed in a public forum
such as Twitter by current and potential users and their partners and ministries of health. We highlight
two broad considerations that merit discussion among interested stakeholders, including policy makers,
program designers, and health advocates. The first relates to the use of Twitter within family planning
programs, and the second relates to themes that require more significant research. Data coupled with
analytical capacity will help policy makers and program designers to effectively leverage Twitter for
expanding the reach of family planning services and influencing social media policy. Our aim is to not
only to contribute to the body of knowledge but also to spur greater engagement by program personnel,
researchers, health advocates and contraceptive users.
Realidades, avances y retos de la ERE
Authors: Serna Collazos Victor Hugo 
Published: September 2021

La Educación Religiosa Escolar (ERE), en la Ley General de Educación colombiana de 1994, es una de las áreas obligatorias en los procesos de formación integral de los ciudadanos, donde por disposiciones constitucionales sobre temas de libertad religiosa y de cultos y por parte del Ministerio de Educación Nacional (MEN) se ha tenido que pensar su naturaleza, su lugar y su implementación en el aula. Dichas exigencias han sido motivo de investigación por académicos, quienes han buscado consolidar la ERE como una disciplina que aporta a los fines de la educación en el país y no de manera confesional, en donde se brinde sentido de vida, compromiso por el otro y por lo trascendental. Además, se reconoce el aporte de la Iglesia Católica al desarrollo de la educación religiosa en Colombia y cómo ha de ser la actitud de los creyentes ante los nuevos retos en esta área.
Esophageal cancer: analytical
indicators of cancer service efficacy
Authors: Toleutaiulу K. , Zhylkaydarova A. , Zhumashev U. , Yessenkulova S. , Jakipbayeva A. , Doszhanov N. 
Published: September 2021

Relevance: Esophageal cancer ranks eighth in the structure of malignant tumors in the Republic of Kazakhstan.
According to the Kazakh Institute of Oncology and Radiology, in 2018, 1225 were primarily registered with esophageal
cancer, and 825 patients died from this disease.
The purpose of this study was to analyze the esophageal cancer incidence and mortality among the population
of the Republic of Kazakhstan in 2009-2018 and determine
the cancer service efficacy.
Results: The analysis of intensive indicators of esophageal cancer incidence showed a decrease in the number of
primary cases from 8.2‰ in 2009 to 6.7‰ in 2018, and
the mortality – from 6.9‰ to 3.8‰. The share of early
detection (Stage I-II) has increased by 38.2% since 2009 to
reach 52.1% in 2018. The share of stage IV esophageal cancer
has decreased from 7.2% in 2009 to 5.8% in 2018. One-year
mortality has decreased by 14.7% since 2009 to reach 41.2%
in 2018, which speaks of the improvements in the timely diagnosis of esophageal cancer. The number of patients who
received radical comprehensive treatment has increased by
8.6% to reach 32.2% in 2018. The number of patients who
received surgical treatment in 2009-2018 remained almost
at the same level and amounted to 18.9 and 18.0%, respectively. However, during the years of screening for esophageal
cancer, the proportion of surgical treatment has increased
from 26.6% to 30.4%. The ratio of incidence to mortality has
decreased from 91.4% to 68.8% in the study period indicating an improvement in the level of cancer service in the Republic of Kazakhstan.
Conclusion: The analysis of intensive indicators of
esophageal cancer incidence showed a decrease in primary
incidence. The screening conducted in 2013-2016 has shown
an improvement in early detection of esophageal cancer
(stages I-II) and a decrease in the share of the advanced
stage. The findings of this study shall serve as the basis for
planning anti-cancer activities
Melanoma: incidence
and mortality in the world
and Kazakhstan in 2018
Authors: Tuleuova D. A. , Serikbaev G. A. , Kurmanaliev A. K. , Pysanova J. U. , Najibulo Sh. P. , Elekbaev A. M. , Voskanyan E. A. 
Published: September 2021

Relevance: Melanoma is one of the most aggressive
and unpredictable tumors. Melanoma most often affects
the skin. Over the past 50 years, the incidence of melanoma in the world has been overgrowing, with the highest
rates among fair-skinned people and in the regions with
lower latitude. The incidence is higher among older adults
but is also one of the common forms of cancer among
young people. Melanoma incidence and mortality depend on gender, age, ethnicity, as well as on the region of
residence.
The purpose of the study was to assess the skin
melanoma epidemiology in the world and Kazakhstan
in 2018.
Results: Melanoma incidence was growing throughout the world during the past decades, with an annual
incidence of 4-6%. Melanoma incidence is expected to
reach 450,000 cases per year in the next two decades.
Kazakhstan has experienced an increase in melanoma
incidence by 63% over the past ten years. Females made
61% of cases. The incidence remained high in the East Kazakhstan region and the cities of Almaty and Karaganda.
High mortality was registered in North Kazakhstan, East
Kazakhstan, and Pavlodar regions, and the city of Almaty.
Since 2009, the five-year survival with melanoma in the
Republic of Kazakhstan has decreased by 2.2%.
Conclusion: Melanoma morbidity and mortality
is growing worldwide. Even though its incidence is below one-tenths of other types of skin cancer, the ability
of melanoma to quickly metastasize and affect young
adults makes this disease as a serious social problem.
It is necessary to improve the methods of primary,
secondary, and tertiary prevention of melanoma aimed
at identifying individuals at high risk of tumor development and optimize the methods of its early diagnostics
and definition of the risk of metastasis.
Multiple Primary Thyroid Cancer
in combination with Malignant
Paraganglioma of the Neck
complicated by Acute Cerebrovascular
Event in the Postoperative Period:
Clinical Case
Authors: Adilbayev G. B. , Kaibarov M. E. , Kydyrbayeva G. Z. , Mykhamadiev B. T. , Sloneva N. V. 
Published: September 2021

Actuality: Paraganglioma originates from the nerve
ganglia along a.carotis, the ganglion of n.vagus, and the
nerve plexuses around the sigmoid sinus, and has a rich
tumor vasculature. Paraganglioma accounts for 0.8% of all
CNS tumors and occurs most often at 40-60 years. Chemodectoma is located in the common carotid artery bifurcation zone and accounts for 2/3 of all glomus tumors.
Purpose: The article describes a clinical case of multiple primary thyroid cancer in combination with malignant
paraganglioma of the neck complicated by acute cerebrovascular event (ACE) in the postoperative period treated at
the Head and Neck Tumor Center of the Kazakh Institute of
Oncology and Radiology.
Results: The presented clinical case demonstrates the
results of the treatment of multiple primary cancer complicated by an ACE in the postoperative period. The qualification of doctors, adequate diagnostics contributed to choosing the right ACE treatment tactics taking into account all
the patient-specific features, the tumor localization, and
possible postoperative complications.
Conclusion: The presented clinical case confirms the
available data on the necessity of all diagnostic procedures
and their effectiveness in the assessment of the prevalence
of the process and the involvement of the adjacent anatomical structures in the suspected chemodectoma to avoid
postoperative consequences that can lead to disability and
fatal outcome. A wrong choice of the volume of surgical intervention can result in severe postoperative complications.
Timely diagnosis and knowledge of the clinical course of the
ACE helped restore the patient’s general condition and stop
signs of cerebral ischemia. Successful recovery of a patient
depends on the qualifications of the doctors and the prevalence of the tumor process. Adequate symptomatic therapy
has a huge impact on the course of a complicated postoperative period.
Analytical review of the demand and
satisfaction of the population with inhome palliative care services for cancer
patients provided by mobile teams
in Almatу
Authors: Ansatbaeva T. N. , Kaidarova D. R. , Kunirova G. Zh. , Izmagambetov N. А. 
Published: September 2021

Relevance: Patients with advanced malignant neoplasms
require constant monitoring and care. Mobile palliative care
(PC) is one of the modern humanistic methods of supporting
terminal cancer patients, as well as their relatives.
The purpose of this study was to analyze the demand
and satisfaction of the population with in-home PC services
for cancer patients provided by mobile teams in Almaty.
Results: According to WHO, the number of people who
need PС services at the end of life is 20.4 million, of whom 94%
are adults (69% are over 60 years, 25% are at the age of 15 to
59), and 6% are children. 34% of patients dying from cancer
need PC services at the end of life. 80% of people in need of
PC services live in lower-middle-income countries. At the end
of 2018, the total number of palliative beds deployed in the
Republic of Kazakhstan amounted to 415 (vs. 373 in 2017).
Conclusion: Given the practical relevance and topicality,
there is an urgent need to develop evidence-based recommendations for optimizing the provision of PC services, as well
as improving the quality of life of cancer patients
Melanoma: incidence and mortality
in the world and Kazakhstan in 2018
Authors: TULEUOVA D. A. , SERIKBAEV G. A. , KURMANALIEV A. K. , PYSANOVA J. U. , NAJIBULO Sh. P. , ELEKBAEV A. M. , VOSKANYAN E. A. 
Published: September 2021

Relevance: Melanoma is one of the most aggressive and unpredictable tumors. Melanoma most often affects the skin.
Over the past 50 years, the incidence of melanoma in the world has been overgrowing. The highest rates were observed among
fair-skinned people and in the regions with lower latitude. The incidence is higher among older adults but is also one of the
common forms of cancer among young people. Melanoma incidence and mortality depend on gender, age, ethnicity, as well
as on the region of residence.
The purpose of the study was to assess the skin melanoma epidemiology in the world and Kazakhstan in 2018.
Results: Melanoma incidence was growing throughout the world during the past decades, with an annual incidence of
4-6%. Melanoma incidence is expected to reach 450,000 cases a year in the next two decades.
Kazakhstan has experienced an increase in melanoma incidence by 63% over the past ten years. Females made 61% of
cases. The incidence remained high in the East Kazakhstan region and the cities of Almaty and Karaganda. High mortality
was registered in North Kazakhstan, East Kazakhstan, and Pavlodar regions, and the city of Almaty. Since 2009, the five-year
survival with melanoma in the Republic of Kazakhstan has decreased by 2.2%.
Conclusion: Melanoma morbidity and mortality is growing worldwide. Even though its incidence is below one-tenths of
other types of skin cancer, the ability of melanoma to quickly metastasize and affect young adults makes this disease as a
serious social problem.
It is necessary to improve the methods of primary, secondary, and tertiary prevention of melanoma aimed at identifying
individuals at high risk of tumor development and optimize the methods of its early diagnostics and definition of the risk of
metastasis
Lung cancer in Kazakhstan: age-gender features
Authors: KAIDAROVA D. R. , SHATKOVSKAYA O. V. , ZHOLDYBAY Zh. Zh. , ZHYLKAIDAROVA A. Zh. , PANINA A. S. 
Published: September 2021

Relevance: Over the years, lung cancer (LC) remains the leading cause of cancer deaths in Kazakhstan. In 2018, LC was
diagnosed in 3741 people in the RK, and 2377 dies from LC.
The purpose of this study was to assess the age-gender characteristics of morbidity and mortality from LC in Kazakhstan
based on statistical and literature data.
Results: The conducted analysis by gender and age showed a consistent and significant increase in LC mortality in the RK,
starting from the age of 40-44 years. The highest incidence and mortality were registered in the age groups of 65-69 years and
70+ years. In general, in all age categories, the incidence and mortality in men exceeded the incidence and mortality in women by
4.5–5.3 times. The highest mortality in men and women of all ages was registered in 2009 (34.3‰ and 6.9‰, respectively), the
lowest – in 2019 (20.8‰ in men and 4.6‰ in women).
Conclusions: The results of the assessment can be used to improve early diagnosis of LC and in the preparation of national
screening programs and regional pilot projects for LC prevention and the identification of risk groups. The use of the results
will contribute to increasing the effectiveness of treatment, improving the five-year survival of patients, reducing the level of
neglect and mortality from LC.
Successful live birth after fertility-sparing
treatment in grade II endometrial cancer:
A case report
Authors: KUKUBASSOV E. K. , BOLATBEKOVA R. O. , SATANOVA A. R. , BERTLEUOV O. O. , KALDYBEKOV D. B. , KOVCHEGOV I. O. 
Published: September 2021

Relevance: The growing incidence of endometrial cancer among young women urges the use of fertility-sparing therapy.
The purpose of this study was to demonstrate the results of using fertility-sparing therapy in a woman with endometrial
cancer, FIGO stage IA GII.
Results: After the combination hormone therapy with gonadotropin-releasing hormone (diphereline 3.75 mg every 28
days) using a hormone-releasing intrauterine device, the patient with endometrial cancer stage 1, GII demonstrated a complete response to treatment and delivered a live newborn.
Conclusion: Surgery remains the primary treatment for the early stages of endometrial cancer. However, hormone therapy
can preserve fertility in young women with highly differentiated early-stage endometrial cancer. The described schemes of
hormone therapy can be used in young patients.
Calculation of the cost-effectiveness
of subcutaneous administration of trastuzumab
Authors: OMAROVA I. M. , NURKETAEVA J. O. , DOROGAN D. D. 
Published: September 2021

Rational selection of medicines with an assessment of their pharmacoeconomic effectiveness is the most effective way to
ensure safe and efficient treatment and economical use of budget funds allocated for drug therapy, as well as to reduce the
time of hospitalization and treatment of patients.
The purpose of the research was to evaluate the pharmacoeconomic effectiveness of using the subcutaneous and intravenous forms of drug Trastuzumab.
Research tasks:
1. Estimate costs when using subcutaneous trastuzumab in an outpatient chemotherapy room (OCR).
2. Estimate costs when using intravenous trastuzumab in a day patient department (DPD).
3. Estimate costs when using intravenous trastuzumab in a round-the-clock hospital.
Results: The paper presents the pharmacoeconomic analysis of targeted therapy with trastuzumab in two forms for intravenous administration (IV) and trastuzumab emtansine for subcutaneous administration (SC) in breast cancer by cost minimization method.
The costs of used drugs are according to the price-list of the unified national distributor SK Pharmacia as of January 1, 2018.
At comparable efficacy and toxicity, the estimated cost-effectiveness of trastuzumab per 100 patients per year is
KZT 16,939,600 ($ 50,972) for SC administration in OCR and IV administration in DPD vs. KZT 41,783,200 ($ 125,728) for
SC administration in OCR and IV administration in a round-the-clock hospital.
Conclusions: Based on the above, the subcutaneous form is economically feasible for conducting targeted therapy with
trastuzumab.
Cutaneous leiomyosarcoma/
atypical smooth muscle sarcoma
Authors: SATBAYEVA E. B. , MUCHAMETGALIEV N. A. , ISKAKOVA E. E. 
Published: September 2021

Relevance: Cutaneous leiomyosarcoma is a rare primary dermal neoplasm, accounting for up to 2-3% of all superficial
sarcomas. It can occur at any age, most likely between the ages of 50 and 70 years. This tumor has a high recurrence potential
in case of insufficiently deep excision. Recurrent tumors are more aggressive and characterized by subsequent metastasis.
The purpose of the study was to demonstrate the results of the histopathological examination of a cutaneous
leiomyosarcoma / atypical smooth muscle tumor.
Results: Cutaneous leiomyosarcoma was represented by spindle-shaped cells with high cellularity located in bundles
and growing expansively, surrounded by a capsule. The nuclei of the cells were elongated, hyperchromic. Cells with atypical
abnormal nuclei were present in smaller quantities. The mitoses, including atypical, were numerous. IHC staining for SMA,
Desmin, H-Caldesmon – diffusely positive on tumor cells. The reaction for S100, Myogenin – negative.
Conclusion: A cutaneous leiomyosarcoma can be finally diagnosed only after a pathomorphological examination of the
specimen and differential diagnostics using additional research methods