bluuebunny/crossref_metadata_2025_split huggingface dataset:
Traitement des cancers de l’endomètre à l’institut Joliot Curie de Dakar : à propos de 30 cas
Authors: Thiam Jaafar , Kahatwa Edouard , Ka Sidy , Dieng Mamadou Moustapha , Diouf Doudou , Diallo Adja Coumba , Gaye Papa Macoumba , Dem Ahmadou 
Published: October 2021

INTRODUCTION : L’objectif de ce travail est d’étudier les aspects thérapeutiques des cancers de l’endomètre à l’Institut Joliot Curie de Dakar. MATERIELS ET METHODES : Il s’agit d’une étude rétrospective menée à l’Institut Joliot Curie de Dakar incluant tous les cas de cancers d’endomètre confirmés par l’histologie entre janvier 2012 et décembre 2016. RESULTATS : Il s’agissait de 30 cas de cancers d’endomètre sur une période de cinq ans. L’adénocarcinome endométrioïde était le type histologique le plus fréquent et était retrouvé chez 25 patientes soit 84% des cas. Les patientes étaient classées stades I et II de FIGO dans 43% des cas, stade III dans 24 % des cas et stade IV dans 33% des cas. La colpo-hystérectomie avec lymphadénectomie pelvienne (CHL) était le principal geste chirurgical effectué. Une radiothérapie externe était effectuée chez trois patientes soit 10%. Un cas de cystite radique ainsi qu’une radiodermite étaient enregistrés comme complication liée à la radiothérapie. Aucune patiente n’a bénéficié de curiethérapie. La chimiothérapie était effectuée chez 17 patientes soit 56,6 %. Elle était adjuvante chez 10 patientes soit 34% des cas. Les récidives pelviennes étaient notées chez trois patientes opérées soit 10%. Après 13 mois de suivi, la survie était de 50%. CONCLUSION : Le traitement du cancer de l’endomètre à l’Institut Joliot Curie de Dakar est marqué par la prépondérance de la chirurgie qui est encadré par la chimiothérapie et/ou la radiothérapie externe.
Evaluation des facteurs pronostiques dans le cancer du sein chez la femme au Sénégal : à propos de 288 cas
Authors: Ndiaye Mamadou , Dieng Souleymane , Thiam Jaafar , Diallo Adja Coumba , Diouf Doudou , Ka Sidy , Dem Ahmadou 
Published: October 2021

INTRODUCTION : Au Sénégal le cancer du sein représente le deuxième cancer féminin et pose un problème de santé public majeur. Le but de ce travail était d’évaluer les facteurs pronostiques dans l’évolution du cancer du sein chez la femme. PATIENTS ET METHODES : Il s'agit d'une étude rétrospective réalisée sur une période sur un an allant du 1er janvier 2008 au 31 Décembre 2008 portant sur l'ensemble des femmes suivies pour cancer du sein au service de cancérologie à l'Institut Joliot Curie. Ainsi, 288 patientes atteintes de cancer du sein ont été colligés. RESULTATS : La moyenne d’âge de nos malades était de 47,32 ans. La parité moyenne était de 4,9 enfants par femme. Vingt-deux soit 7% des patientes avaient un antécédent de cancer. Cliniquement, la taille tumorale était classée T4 chez 180 patientes soit 81%. Une atteinte ganglionnaire chez 188 patientes (65,2%). Le type histologique le plus fréquent était le carcinome canalaire infiltrant avec 90,3% des cas. Une prédominance des grades SBRII et SBRIII a été observé (respectivement 41% et 46%). Les récepteurs hormonaux (RH) étaient positifs dans huit cas (24%). La surexpression du gène HER2 était retrouvée chez seulement quatre patientes sur 30. Les limites de la chirurgie étaient précisées chez 48 patientes avec des marges envahies chez sept patientes (14,5%). La présence d'emboles vasculaires était notée chez 18 patientes parmi les 29 dont la recherche a été effectuée chez 179 patientes soit 62%. Au moment du diagnostic initial, 45 patientes soit 19,7% des malades présentaient au moins une métastase distance. La majorité des patientes étaient reçues à un stade avancé (89%, classées entre stade III et IV). Une seule patiente était reçue au stade I. La survie globale pour les cancers du sein était à 72% à 3 ans et 30% à 5 ans. La survie globale à 5 ans des patientes au stade localisé de la maladie était de 85% contre 5% pour les patientes au stade avancé. CONCLUSION : Les facteurs pronostiques sont multiples et souvent péjoratifs chez nos patients avec une prédominance des femmes jeunes, des cancers localement avancés et des formes biologiques agressifs.
Dwelling Time Terhadap Kegiatan Bongkar Muat Mv Meratus Kendari 1 Di PT Meratus Line Cabang Banjarmasin
Authors: Kamsariaty Kamsariaty , Fathulliansyah Noor , Ratna Purnomo Evi 
Published: October 2021

Penelitian pada Dwelling Time merupakan waktu dihitung mulai dari suatu container dibongkar dari kapal sampai petikemas tersebut meninggalkan terminal pelabuhan melalui pintu utama. Rata-rata dwelling time kurang atau sama dengan 3 hari yaitu untuk rute Jakarta – Semarang – Banjarmasin dengan frequency kedatangan every 5,0 days dan perlu adanyapengoptimalkan kinerja yang sesuai semaksimal mungkin dengan melakukan koordinasi agar dapat merealisasikan tugas masing- masing pihak agar sesuai dengan SOP yang berlaku sehingga semua kegiatan dapat berjalan sebagai mana mestinya guna memangkas dwelling time, karena akan berpengaruh dalam jadwal kerja kapal dan kondisi container pada saat bongkar muat .Penelitian ini bertujuan untuk memberikan informasi tentang Proses Dwelling Time yang terjadi di Terminal Petikemas Banjarmasin, penelitian ini menggunakan Pendekatan Kualitatif. Penelitian kualitatif yaitu penelitian yang tidak menggunakan perhitungan. Atau diistilahkan dengan penelitian ilmiah yang menekankan pada karakter alamiah sumber data yang didapatkan setelah melakukan observasi, wawancara, dan dokumentasi yang bertujuan mendeskripsikan proses Dwelling Time terhadap kegiatan bongkar muat Mv. Meratus Kendari 1 di PT Meratus Line Cabang Banjarmasin.
Assessment of the resistance of highly ornamental plants of autochthonous flora to increased concentrations of pollutants
Authors: Shutava H. G. , Bashilov A.V. , Sedun E.A. , Vaitsekhouskaya A.A. , Onete M. 
Published: October 2021

Aim. The purpose of the work is to assess the resistance of highly decorative plants of the native flora to a high level of salinity and the content of zinc, lead and cadmium for landscaping urban and roadside areas. Methods. We used seed germination under laboratory conditions with soaking in solutions of sodium chloride and salts of zinc, lead and cadmium, as well as the method of in vitro cell selection to increase resistance to salinity of Verbascum nigrum L. Results. The resistance of 7 species of highly decorative plants, representatives of the autochthonous flora of Belarus, to increasing concentrations of lead, zinc and cadmium salts was assessed. Germination capacity, length and morphology of roots, length of seedlings during germination of seeds of Betonica officinalis L., Centaurea jacea L., Verbascum nigrum, Knautia arvensis (L.) Coult., Galium verum L., Anthemis tinctoria L., Anthemis arvensis L., Viscaria vulgaris Bernh., Achillea millefolium L. in the presence of sodium chloride are shown. It has been shown that the in vitro cell selection method is promising for the selection of resistant lines of Verbascum nigrum. Conclusions. The presence of lead, zinc and cadmium salts had a significant effect on the average length of the root, hypocotyl, and cotyledonous leaves, as well as the germination capacity of highly decorative species of autochthonous flora. The most resistant to salinity were yarrow (Achillea millefolium), brown knapweed (Centaurea jacea) and black mullein (Verbascum nigrum). Lines of Verbascum nigrum, capable of growing in vitro at a sodium chloride concentration of 5 g/L, were selected. Keywords: salinity, heavy metals, seed germination, highly decorative species.
Des passagers en réseaux sur le colombie (Déc. 1935-Janv. 1936) ; construction d’une fiction transatlantique
Authors: Lozère Christelle 
Published: October 2021

La Croisière du Tricentenaire scénarise par une mise en scène spectaculaire, l’arrivée des délégations officielles, porteuses dans la Caraïbe des valeurs françaises, venues en nombre depuis le Havre pour inaugurer et célébrer les trois cents ans de la colonisation des Antilles et de la Guyane. Avec ses 366 passagers en réseaux, le paquebot Le Colombie des Messageries transatlantiques rassemble l’élite coloniale, politique, savante et artistique de métropole venue en représentation officielle. Il s’agira d’analyser cette fiction transatlantique au coeur de la propagande républicaine assimilationniste tout en traduisant la légèreté de cette croisière éphémère.
Changes in the spike and nucleocapsid protein of porcine epidemic diarrhea virus strain in Vietnam—a molecular potential for the vaccine development?
Authors: Tran Thach Xuan , Lien Nguyen T.K. , Thu Ha T. , Duy Nguyen Dinh , Duong Bui T.T. , Quyen Dong Van 
Published: October 2021

BackgroundPorcine epidemic diarrhea virus (PEDV) is a dangerous virus causing large piglet losses. PEDV spread rapidly between pig farms and caused the death of up to 90% of infected piglets. Current vaccines are only partially effective in providing immunity to suckling due to the rapid dissemination and ongoing evolution of PEDV.MethodsIn this study, the complete genome of a PEDV strain in Vietnam 2018 (IBT/VN/2018 strain) has been sequenced. The nucleotide sequence of each fragment was assembled to build a continuous complete sequence using the DNASTAR program. The complete nucleotide sequences and amino acid sequences of S, N, and ORF3 genes were aligned and analyzed to detect the mutations.ResultsThe full-length genome was determined with 28,031 nucleotides in length which consisted of the 5′UTR, ORF1ab, S protein, ORF3, E protein, M protein, N protein, and 3′UTR region. The phylogenetic analysis showed that the IBT/VN/2018 strain was highly virulent belonged to the G2b subgroup along with the Northern American and Asian S-INDEL strains. Multiple sequence alignment of deduced amino acids revealed numerous mutations in the S, N, and ORF3 regions including one substitution766P > L766in the epitope SS6; two in the S0subdomain (135DN136>135SI136and N144> D144); two in subdomain SHR1at aa1009L > M1009and1089S > L1089; one at aa1279P > S1279in subdomain SHR2of the S protein; two at aa364N > I364and378N > S378in the N protein; four at aa25L > S25,70I > V70,107C > F107, and168D > N168in the ORF3 protein. We identified two insertions (at aa59NQGV62and aa145N) and one deletion (at aa168DI169) in S protein. Remarkable, eight amino acid substitutions (294I > M294,318A > S318,335V > I335,361A > T361,497R > T497,501SH502>501IY502,506I > T506,682V > I682, and777P > L777) were found in SAsubdomain. Besides, N- and O-glycosylation analysis of S, N, and ORF3 protein reveals three known sites (25G+, 123N+, and 62V+) and three novel sites (144D+, 1009M+, and 1279L+) in the IBT/VN/2018 strain compared with the vaccine strains. Taken together, the results showed that mutations in the S, N, and ORF3 genes can affect receptor specificity, viral pathogenicity, and the ability to evade the host immune system of the IBT/VN/2018 strain. Our results highlight the importance of molecular characterization of field strains of PEDV for the development of an effective vaccine to control PEDV infections in Vietnam.
Farmer Producer Companies in India: An Overview
Authors: Senthil Nathan T. S. , Palanichamy N. Venkatesa 
Published: October 2021

Farmer Producer Companies (FPCs) have emerged as a solution to the problems that small and marginal farmers confront with. This study probed into the reasons for the farmer-producer companies’ establishment, as stated in different policy documents and past literature. Performance of Farmers Producer Companies has improved significantly; however, the emergence of FPCs in India has not been consistent across the states. This paper examines the current status, geographical spread and functions of Farmer's Producer Companies (FPCs) across India, as well as suggests suitable measure to their performance. The study indicated that a total of 6471 FPCs were formed, in which around 80 per cent i.e. 5145 FPCs were promoted by Small Farmers Agri-business Consortium (SFAC) and National Bank for Agriculture and Rural Development (NABARD), 1263 FPCs were promoted by various state government and other agencies, and 63 of them were self-promoted. More than 50 per cent of the FPCs are set up in Maharashtra, Madhya Pradesh, Uttarakhand, West Bengal, Karnataka, Odisha and Telangana. SFAC promoted large number of FPCs in Madhya Pradesh (149 FPCs) and NABARD has promoted large number of FPCs in Uttarakhand (362). The number of farmers mobilised through FPCs by SFAC and NABARD were highest in the state of Madhya Pradesh with 183517 farmer members, followed by Karnataka with 176732 farmer members. There were a number of factors that influenced state performance, and this study suggested some strategies to overcome them in order to promote the growth of FPCs in India.
Effect of Myofascial Release Technique Verses Conventional Therapy in Tension Neck Syndrome: A Research Protocol
Authors: Nagore Aditi N. , Patil Deepali S. , Wadhokar Om C. 
Published: October 2021

Background: A pain in the neck and shoulder region is referred to as tension neck syndrome. Symptoms include neck and shoulder muscular discomfort, pain, tiredness, and stiffness, as well as headaches. Palpable stiffening patches, sensitive sots, and spasms on the trapezius or sternocleidomastoid muscles may be identified during the physical examination, which are commonly coupled with neck pain on the opposing side, as well as a decreased range of flexion, extension, or rotation. Tension neck syndrome is a prevalent occurrence among computer users.
Methods: The participants (n=30) will be recruited in the study suffering from tension neck syndrome and meeting the inclusion criteria. Two groups will be formed such that patients in group A will be treated by myofascial release technique whereas group B will be treated by conventional therapy. The protocol will cover 2 weeks of treatment. Regular assessment will be carried out. In the rehabilitation period, we will evaluate activity of daily living. Our outcome measures will be Neck Disability Index (NDI) and Visual Analogue Scale (VAS).
Discussion: Tension neck syndrome is more common in women than in men, and it is linked to computer users including office professionals, students, and others. Efficacy of the myofascial release technique verses conventional therapy will be evaluated by using Neck Disability Index (NDI) and Visual Analogue Scale (VAS). The result of the study will significantly provide affirmation on using myofascial release technique verses conventional therapy in tension neck syndrome patients.
Computational approaches to detect small lesions in 18F‐FDG PET/CT scans
Authors: Nichols Kenneth J. , DiFilippo Frank P. , Palestro Christopher J. 
Published: October 2021

AbstractPurposeWhen physicians interpret 18F‐FDG PET/CT scans, they rely on their subjective visual impression of the presence of small lesions, the criteria for which may vary among readers. Our investigation used physical phantom scans to evaluate whether image texture analysis metrics reliably correspond to visual criteria used to identify lesions and accurately differentiate background regions from sub‐centimeter simulated lesions.MethodsRoutinely collected quality assurance test data were processed retrospectively for 65 different 18F‐FDG PET scans performed of standardized phantoms on eight different PET/CT systems. Phantoms included 8‐, 12‐, 16‐, and 25‐mm diameter cylinders embedded in a cylindrical water bath, prepared with 2.5:1 activity‐to‐background ratio emulating typical whole‐body PET protocols. Voxel values in cylinder regions and background regions were sampled to compute several classes of image metrics. Two experienced physicists, blinded to quantified image metrics and to each other's readings, independently graded cylinder visibility on a 5‐level scale (0 = definitely not visible to 4 = definitely visible).ResultsThe three largest cylinders were visible in 100% of cases with a mean visibility score of 3.3 ± 1.2, while the smallest 8‐mm cylinder was visible in 58% of cases with a significantly lower mean visibility score of 1.5±1.1 (P < 0.0001). By ROC analysis, the polynomial‐fit signal‐to‐noise ratio was the most accurate at discriminating 8‐mm cylinders from the background, with accuracy greater than visual detection (93% ± 2% versus 76% ± 4%, P = 0.0001), and better sensitivity (94% versus 58%, P < 0.0001).ConclusionImage texture analysis metrics are more sensitive than visual impressions for detecting sub‐centimeter simulated lesions. Therefore, image texture analysis metrics are potentially clinically useful for 18F‐FDG PET/CT studies.
Vascular Ultrasound for Giant Cell Arteritis: Establishing a Protocol Using Vascular Sonographers in a Fast‐Track Clinic in the United States
Authors: Oshinsky Charles , Bays Alison M. , Sacksen Ingeborg , Jernberg Elizabeth , Zierler R. Eugene , Diamantopoulos Andreas P. , Liew Jean W. , Chung Sarah H. , Pollock P. Scott 
Published: October 2021

ObjectiveWe developed a fast‐track clinic (FTC) to expedite the evaluation of patients suspected of having giant cell arteritis (GCA) using vascular ultrasound. Though FTCs have demonstrated efficacy in Europe, no protocolized clinic in the United States has been developed. This study introduces a new FTC model unique to the United States, using vascular sonographers, and describes the protocols used to develop reliable findings. We evaluate clinical outcomes using vascular ultrasound and temporal artery biopsy (TAB).MethodsA retrospective review included all subjects referred to the University of Washington FTC aged 50 years old or older who received both ultrasound and TAB between November 2017 and November 2019. Ultrasound was performed by a vascular sonographer trained in GCA detection. Ultrasound results were read by a vascular surgeon and reviewed by four rheumatologists certified in musculoskeletal ultrasound who had completed a course in vascular ultrasound use in GCA and large‐vessel vasculitis.ResultsA total of 43 subjects underwent both vascular ultrasound and TAB. Six subjects had both positive ultrasound and TAB results. There were also seven positive ultrasound results in patients with negative TAB results, most due to detection of large‐vessel GCA (LV‐GCA). All 29 subjects with negative ultrasound results had negative TAB results.ConclusionThis is the first study in the United States to demonstrate a reliable FTC protocol using vascular sonographers. This protocol demonstrated good agreement between ultrasound and TAB and allowed for the detection of additional cases of LV‐GCA by vascular ultrasound. Vascular ultrasound improved the rate of GCA diagnosis primarily by detecting additional cases of LV‐GCA.
Stable Cycling of All‐Solid‐State Batteries with Sacrificial Cathode and Lithium‐Free Indium Layer
Authors: Park Sang Wook , Choi Hong Jun , Yoo Yiseul , Lim Hee‐Dae , Park Jun‐Woo , Lee Yoo‐Jin , Ha Yoon‐Cheol , Lee Sang‐Min , Kim Byung Gon 
Published: October 2021

AbstractAll‐solid‐state batteries (ASSBs) comprising solidified cathodes, electrolytes, and Li–metal anodes have attracted notable attention as promising future batteries for electric vehicles owing to their exceptional stability and expectation of achieving high energy density. However, its permanent operation has been hindered by Li dendrite growth, chemo–mechanical degradation, and interfacial instability, leading to Li exhaustion, increased resistance, and internal short‐circuiting. Herein, for the first time, the authors report the effects of a lithium nitride (Li3N) sacrificial cathode on the cycling performance of ASSBs combined with a Li‐free In layer. Through in situ evolved gas and internal pressure change analyses of the cells, it is found that, as with the liquid electrolyte cell, the decomposed Li3N compensates for active Li consumed by side reactions in the cell. Moreover, it is demonstrated that the improved interparticle contact by volume expansion of In through additionally supplied Li as well as the interfacial stability at the anode side by the dendrite‐free In layer, are strongly responsible for the improved cyclability of the ASSBs. The findings reveal the effectiveness of the Li compensation approach for the stable cycling of ASSBs based on the secured interfacial stability at the anode side.
Reversible Cation‐Mediated Anionic Redox in Defect Spinel Structure for High Power Batteries
Authors: Bakierska Monika , Chudzik Krystian , Świętosławski Michał , Klejna Sylwia , Kubicka Marcelina , Marciszko‐Wiąckowska Marianna , Gajewska Marta , Walas Stanisław , Molenda Marcin 
Published: October 2021

AbstractWith ever‐increasing energy demand, more efforts are dedicated to designing innovative electrode materials providing higher storage capability and power output. As it has been demonstrated recently, the use of mixed cation–anion redox reactions opens up new possibilities for the significant rise of material's capacity and unusual electrochemical characteristics of lithium‐ion battery electrodes. In this paper, a new type of fast cation‐mediated anionic redox reaction in the 3D spinel structure is presented. Li0.98K0.01Mn1.86Ni0.11O4 shows 170% of stoichiometric spinel theoretical capacity without voltage hysteresis or significant capacity and voltage fading attributed to limitations of reversible anionic redox. The authors’ sol–gel‐derived defect spinel structure can deliver 250 mAh g−1 at 1C and retain 64% of this capacity under a high 50C current rate. The observed electrochemical process shows the reversibility unseen before in mixed cation–anion redox cathode materials for Li‐ion systems.
Large Tunneling Magnetoresistance in van der Waals Ferromagnet/Semiconductor Heterojunctions
Authors: Zhu Wenkai , Lin Hailong , Yan Faguang , Hu Ce , Wang Ziao , Zhao Lixia , Deng Yongcheng , Kudrynskyi Zakhar R. , Zhou Tong , Kovalyuk Zakhar D. , Zheng Yuanhui , Patanè Amalia , Žutić Igor , Li Shushen , Zheng Houzhi , Wang Kaiyou 
Published: October 2021

Abstract2D layered chalcogenide semiconductors have been proposed as a promising class of materials for low‐dimensional electronic, optoelectronic, and spintronic devices. Here, all‐2D van der Waals vertical spin‐valve devices, that combine the 2D layered semiconductor InSe as a spacer with the 2D layered ferromagnetic metal Fe3GeTe2 as spin injection and detection electrodes, are reported. Two distinct transport behaviors are observed: tunneling and metallic, which are assigned to the formation of a pinhole‐free tunnel barrier at the Fe3GeTe2/InSe interface and pinholes in the InSe spacer layer, respectively. For the tunneling device, a large magnetoresistance (MR) of 41% is obtained under an applied bias current of 0.1 µA at 10 K, which is about three times larger than that of the metallic device. Moreover, the tunneling device exhibits a lower operating bias current but a more sensitive bias current dependence than the metallic device. The MR and spin polarization of both the metallic and tunneling devices decrease with increasing temperature, which can be fitted well by Bloch's law. These findings reveal the critical role of pinholes in the MR of all‐2D van der Waals ferromagnet/semiconductor heterojunction devices.