bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hate and harassment in academia: the rising concern of the online environment
Authors: Oksanen Atte , Celuch Magdalena , Latikka Rita , Oksa Reetta , Savela Nina 
Published: November 2021

AbstractHostile online communication is a global concern. Academic research and teaching staff are among those professionals who routinely give public comments and are thus vulnerable to online attacks. This social psychological and criminological study investigated online harassment victimization among university researchers and teachers. Survey participants (N = 2,492) were university research and teaching staff members from five major universities in Finland. Victimization was assessed with a 20-item inventory. The study included a wide range of both background and general measures on well-being at work. Participants also took part in an online experiment involving a death threat targeting a colleague. Results showed that 30% of the participants reported being victims of online harassment during the prior 6 months. Victims were more often senior staff members, minority group members, and from the social sciences and humanities. Those active in traditional or social media were much more likely to be targeted. Victims reported higher psychological distress, lower generalized trust, and lower perceived social support at work than non-victims. Individuals who were targeted by a colleague from their work community reported higher post-traumatic stress disorder scores and a higher impact of perceived online harassment on their work compared to other victims. In the experimental part of the study, participants reported more anxiety when a close colleague received a death threat. Participants also recommended more countermeasures to a close colleague than to an unknown person from the same research field. Results indicate that online harassment compromises well-being at work in academia. There is an urgent need to find ways of preventing online harassment, both in workplaces and in society at large.
Quinone binding in respiratory complex I: Going through the eye of a needle. The squeeze-in mechanism of passing the narrow entrance of the quinone site
Authors: Dhananjayan Nithin , Wang Panyue , Leontyev Igor , Stuchebrukhov Alexei A. 
Published: November 2021

AbstractAt the joint between the membrane and hydrophilic arms of the enzyme, the structure of the respiratory complex I reveals a tunnel-like Q-chamber for ubiquinone binding and reduction. The narrow entrance of the quinone chamber located in ND1 subunit forms a bottleneck (eye of a needle) which in all resolved structures was shown to be too small for a bulky quinone to pass through, and it was suggested that a conformational change is required to open the channel. The closed bottleneck appears to be a well-established feature of all structures reported so-far, both for the so-called open and closed states of the enzyme, with no indication of a stable open state of the bottleneck. We propose a squeeze-in mechanism of the bottleneck passage, where dynamic thermal conformational fluctuations allow quinone to get in and out. Here, using molecular dynamics simulations of the bacterial enzyme, we have identified collective conformational changes that open the quinone chamber bottleneck. The model predicts a significant reduction—due to a need for a rare opening of the bottleneck—of the effective bi-molecular rate constant, in line with the available kinetic data. We discuss possible reasons for such a tight control of the quinone passage into the binding chamber and mechanistic consequences for the quinone two-electron reduction.
Graphic abstract
ATMOSPHERIC RADIOCARBON FOR THE PERIOD 1950–2019
Authors: Hua Quan , Turnbull Jocelyn C , Santos Guaciara M , Rakowski Andrzej Z , Ancapichún Santiago , De Pol-Holz Ricardo , Hammer Samuel , Lehman Scott J , Levin Ingeborg , Miller John B , Palmer Jonathan G , Turney Chris S M 
Published: November 2021

ABSTRACTThis paper presents a compilation of atmospheric radiocarbon for the period 1950–2019, derived from atmospheric CO2 sampling and tree rings from clean-air sites. Following the approach taken by Hua et al. (2013), our revised and extended compilation consists of zonal, hemispheric and global radiocarbon (14C) data sets, with monthly data sets for 5 zones (Northern Hemisphere zones 1, 2, and 3, and Southern Hemisphere zones 3 and 1–2). Our new compilation includes smooth curves for zonal data sets that are more suitable for dating applications than the previous approach based on simple averaging. Our new radiocarbon dataset is intended to help facilitate the use of atmospheric bomb 14C in carbon cycle studies and to accommodate increasing demand for accurate dating of recent (post-1950) terrestrial samples.
Is the fiṭra mutable? A reformist conception of human perfection in Shāh Walī Allāh's Ḥujjat Allāh al-Bāligha
Authors: von Doetinchem de Rande Raissa A. 
Published: November 2021

AbstractThis article examines the question of whether the created human nature, or fiṭra, is portrayed as mutable in Shāh Walī Allāh's (d. 1762) Ḥujjat Allāh al-Bāligha. I argue that Walī Allāh uses the fiṭra — or the perfection of four qualities that make for human flourishing — to anchor a unified concept of human perfection that can fit different ages without essentially changing. Walī Allāh accomplishes this by affirming the particularity of divine laws and the efficacy of local customs in realising the eternal demands of the human form. More specifically, he posits that established practices can become second nature to a community, enter the divine system of requital, and thus help a people develop the necessary qualities through highly contingent means, all without violating the Qur'anic and traditional claim that the original nature itself never changes. With recourse to some of his other works and potential influences, I conclude that Walī Allāh's conception of the fiṭra accommodates traditional theological assertions regarding the singularity of human perfection, on the one hand, and the possibility of reformed norms, on the other.
Retreat of the Great Escarpment of Madagascar From Geomorphic Analysis and Cosmogenic 10Be Concentrations
Authors: Wang Yanyan , Willett Sean D. , Wu Datian , Haghipour Negar , Christl Marcus 
Published: November 2021

AbstractThe eastern margin of Madagascar has a prominent relief change from the flat coastal plain to the low‐relief high plateau, characterizing a typical great escarpment topography at a passive margin. A quantification of the spatial distribution of erosion rates is necessary to understand the rate of landscape evolution. We present catchment‐averaged erosion rates from detrital cosmogenic 10Be concentrations, systematically covering distinct morphological zones of the escarpment. Erosion rates are differentiated across the escarpment, where the high plateau and the coastal plain are slowly eroding with an average rate of 9.7 m/Ma, and the escarpment basins are eroding faster with an average rate of 16.6 m/Ma. The Alaotra‐Ankay Graben related basins have the highest erosion rate with an average rate of 27 m/Ma. The spatial pattern of erosion rates indicates a retreating escarpment landscape. Retreat rates calculated from the 10Be concentrations are from 182 to 1,886 m/Ma. The rates of escarpment retreat on Madagascar are consistent with a model of a steady retreat from the coastline since the time of rifting, similar to the Western Ghats escarpment on its conjugate margin of the India Peninsula.
Analyzing artificial intelligence systems for the prediction of atrial fibrillation from sinus-rhythm ECGs including demographics and feature visualization
Authors: Melzi Pietro , Tolosana Ruben , Cecconi Alberto , Sanz-Garcia Ancor , Ortega Guillermo J. , Jimenez-Borreguero Luis Jesus , Vera-Rodriguez Ruben 
Published: November 2021

AbstractAtrial fibrillation (AF) is an abnormal heart rhythm, asymptomatic in many cases, that causes several health problems and mortality in population. This retrospective study evaluates the ability of different AI-based models to predict future episodes of AF from electrocardiograms (ECGs) recorded during normal sinus rhythm. Patients are divided into two classes according to AF occurrence or sinus rhythm permanence along their several ECGs registry. In the constrained scenario of balancing the age distributions between classes, our best AI model predicts future episodes of AF with area under the curve (AUC) 0.79 (0.72–0.86). Multiple scenarios and age-sex-specific groups of patients are considered, achieving best performance of prediction for males older than 70 years. These results point out the importance of considering different demographic groups in the analysis of AF prediction, showing considerable performance gaps among them. In addition to the demographic analysis, we apply feature visualization techniques to identify the most important portions of the ECG signals in the task of AF prediction, improving this way the interpretability and understanding of the AI models. These results and the simplicity of recording ECGs during check-ups add feasibility to clinical applications of AI-based models.
Comparing the clinical efficacy of COVID-19 vaccines: a systematic review and network meta-analysis
Authors: Rotshild Victoria , Hirsh-Raccah Bruria , Miskin Ian , Muszkat Mordechai , Matok Ilan 
Published: November 2021

AbstractNew Coronavirus Disease 2019 (COVID-19) vaccines are available to prevent the ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic. We compared the efficacy of new COVID-19 vaccines to prevent symptomatic and severe disease in the adult population and to prevent symptomatic COVID-19 among the elderly. Leading medical databases were searched until August 30, 2021. Published phase 3 randomized controlled trials (RCTs) evaluated efficacy of the vaccine to prevent symptomatic and sever COVID-19 in adults were included. Two reviewers independently evaluated the literature search results and independently extracted summary data. The risk of bias was evaluated using the Cochrane Risk of Bias Assessment Tool. We performed a network meta-analysis (NMA) according to PRISMA-NMA 2015 to pool indirect comparisons between different vaccines regarding their relative efficacy. The primary outcomes were the efficacy of the vaccine against symptomatic COVID-19 in adults (PROSPERO registration number: CRD42021235364). Above 200,000 adult participants from eight phase 3 RCTs were included in NMA, of whom 52% received the intervention (active COVID-19 vaccine). While each of nine vaccines was tested in the unique clinical trial as compared to control, based on indirect comparison, BNT162b2 and mRNA-1273 vaccines were ranked with the highest probability of efficacy against symptomatic COVID-19 (P-scores 0.952 and 0.843, respectively), followed by Gam-COVID-Vac (P-score 0.782), NVX-CoV23730 (P-score 0.700), CoronaVac (P-score 0.570), BN02 (P-score 0.428), WIV04 (P-score 0.327), and Ad26.COV2.S (P-score 0.198). No statistically significant difference was seen in the ability of the vaccines to prevent symptomatic disease in the elderly population. No vaccine was statistically significantly associated with a decreased risk for severe COVID-19 than other vaccines, although mRNA-1273 and Gam-COVID-Vac have the highest P-scores (0.899 and 0.816, respectively), indicating greater protection against severe disease than other vaccines. In our indirect comparison, the BNT162b2 and mRNA-1273 vaccines, which use mRNA technology, were associated with the highest efficacy to prevent symptomatic COVID-19 compared to other vaccines. This finding may have importance when deciding which vaccine to use, together with other important factors as availability of the vaccines, costs, logistics, side effects, and patient acceptability.
Embolization of Type 2 Endoleaks in the Abdominal Aorta Using Ethylene Vinyl Alcohol Copolymer
Authors: Nolte-Ernsting Claus , Mecklenbeck Frank-Peter , Stehr Alexander 
Published: November 2021

Background Type 2 endoleaks (T2EL) are the most frequent complication following endovascular aortic repair. Multiple studies primarily deal with the technical and clinical success of the embolization of persisting T2EL, thereby revealing controversial outcomes. Current reports rarely focus on the detailed execution of such a complex interventional procedure with respect to the difficult anatomic setting.
Methods The present review provides an in-depth depiction and evaluation of the interventional methodology of the embolization of T2EL in the abdominal aorta with use of ethylene vinyl alcohol copolymer (EVOH). Complicating anatomic conditions are taken into account as well as technical and clinical success rates.
Results Using the transarterial approach, there are at least 4 different pathways to access the nidus of a T2EL. CT-guided direct puncture of the aneurysm sac provides an alternative method of high technical success. EVOH with its slow solidification characteristics enables good control to achieve complete filling of the T2EL. During the intervention, however, it remains difficult to meet exactly the embolization endpoint, especially in large T2ELs.
Conclusion T2EL embolization using EVOH is an effective treatment with low major complication rates when conducted by skilled interventionists with detailed knowledge of diverse complex access routes.
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Special Considerations of Anastomotic Leak in Patients with Rectal Cancer
Authors: Cauley Christy E. , Kalady Matthew F. 
Published: November 2021

AbstractAnastomotic leak in patients with rectal cancer has the potential to cause worse oncologic outcomes in addition to major morbidity and mortality risk of this dreaded complication. Anatomic location of the rectal cancer determines the ability to perform a restorative operation and the height of the anastomosis in relation to the anal canal. Clinical staging dictates the need for neoadjuvant treatment (such as chemotherapy and radiation) which may also contribute to anastomotic leak risk. In addition to oncologic outcomes, anastomotic leak can impact bowel function, the need for permanent stoma, and long-term quality of life. This study will discuss special considerations for anastomotic leak prevention and clinical implications of this complication in patients with rectal cancer.
A Novel Nonsurgical Technique for Correcting Congenital Auricular Anomalies
Authors: Duvdevani Shay I. , Knoller Hadas , Rozendorn Noa , Alon Eran E. , Madgar Ory 
Published: November 2021

AbstractCongenital ear anomalies are associated with psychological morbidity. Ear deformities can usually be corrected by nonsurgical techniques such as splinting or molding in the neonatal period, initiated before 6 weeks. Without early corrections, many will require otoplasty during childhood. We introduce a novel silicone-based custom mold technique for congenital ear anomalies. The highly malleable silicone was pushed into every part of the auricle, enabling the auricle to remain in the desired shape, with new molds made weekly. Of 31 newborns (18 males, 13 females), 54 ears were treated. Average age at treatment initiation was 26.8 days. The mean treatment duration was 43.2 days, with a median of 28 days. Normal appearance and parent's satisfaction were achieved in 30 patients with 49 deformed ears and also in four newborns older than 6 weeks. Three concha type microtia in two patients achieved great improvements and parents' satisfaction. No complications were reported. Marked aesthetic improvements and normal appearance were achieved for all deformed auricles treated, and improvements in the concha type microtia will partially alleviate future surgical corrections. The results are not inferior to other techniques. The advantages are as follows: cost-effective, time-saving, simple to master, no need for hair shaving, and easy use for parents. Patients older than 6 weeks of age achieved normal auricle appearance, enabling the correction in older newborns. Custom made silicone auricle molding offers a simple nonsurgical technique for correcting congenital ear anomalies, alleviating the need for future surgical corrections.
East Tusom
Authors: Mortensen David R. , Picone Jordan 
Published: November 2021

Abstract
East Tusom is a Tibeto-Burman language of Manipur, India, belonging to the Tangkhulic group. While it shares some innovations with the other Tangkhulic languages, it differs markedly from “Standard Tangkhul” (which is based on the speech of Ukhrul town). Past documentation is limited to a small set of hastily transcribed forms in a comparative reconstruction of Tangkhulic rhymes (Mortensen & Miller 2013; Mortensen 2012). This paper presents the first substantial sketch of an aspect of the language: its (descriptive) phonetics and phonology. The data are based on recordings of an extensive wordlist (730 items) and one short text, all from one fluent native speaker in her mid-twenties. We present the phonetic inventory of East Tusom and a phonemicization, with exhaustive examples. We also present an overview of the major phonological patterns and generalizations in the language. Of special interest are a “placeless nasal” that is realized as nasalization on the preceding vowel unless it is followed by a consonant, and numerous plosive-fricative clusters (where the fricative is roughly homorganic with the following vowel) that have developed from historical aspirated plosives. A complete wordlist, organized by gloss and semantic field, is provided as appendices.
From One to Many: Identifying Issues in CJEU Jurisprudence
Authors: Schroeder Philipp , Lindholm Johan 
Published: November 2021

AbstractResearch of judges and courts traditionally centers on judgments, treating each judgment as a unit of observation. However, judgments often address multiple distinct and more or less unrelated issues. Studying judicial behavior on a judgment level therefore loses potentially important details and risks drawing false conclusions from the data. We present a method to assist researchers with splitting judgments by issues using a supervised machine learning classifier. Applying our approach to splitting judgments by the Court of Justice of the European Union into issues, we show that this approach is practically feasible and provides benefits for text-based analysis of judicial behavior.
Narrowband-to-broadband switchable and polarization-insensitive terahertz metasurface absorber enabled by phase-change material
Authors: Badri S Hadi , Gilarlue M M , SaeidNahaei Sanam , Kim Jong Su 
Published: November 2021

Abstract
A terahertz absorber with controllable and switchable bandwidth that is insensitive to polarization is of great interest. Here, we propose and demonstrate a metasurface absorber with switchable bandwidth based on a phase-change material of vanadium dioxide (VO2) and verify its performance by finite element method simulations. The metasurface absorber is composed of a hybrid cross fractal as a resonator separated from a gold ground plane by a polyimide spacer. Switching from narrowband to broadband absorber is achieved via connecting VO2 patches to the gold first-order cross fractal converting the resonator to a third-order cross fractal. In the insulator phase of VO2, the main narrowband absorption occurs at the frequency of 6.05 THz with a 0.99 absorption and a full-width half-maximum (FWHM) of 0.35 THz. Upon insulator-to-metal transition of VO2, the metasurface achieves a broadband absorption with FWHM of 6.17 THz. The simulations indicate that by controlling the partial phase transition of VO2, we can tune the bandwidth and absorption level of the absorber. Moreover, the designed absorber is insensitive to polarization due to symmetry and works well for a very wide range of incident angles. In the metallic state of VO2, the absorber has an absorption exceeding 0.5 in the 3.57–8.45 THz frequency range with incident angles up to 65°.
Developing echolocation: distinctive patterns in the ontogeny of the tympanoperiotic complex in baleen and toothed whales (Cetacea)
Authors: Lanzetti Agnese , Crouch Natasha , Portela Miguez Roberto , Fernandez Vincent , Goswami Anjali 
Published: November 2021

Abstract
Cetaceans (baleen and toothed whales) present a unique set of adaptations for life in water. Among other abilities, the two living groups can hear and produce different sound frequencies: baleen whales use low frequencies primarily for communication, whereas toothed whales acquired the ability to echolocate using high-frequency sounds. Both groups exhibit modifications to the morphology of the ear bones (tympanic bulla and periotic) that closely track their behaviour and ecology. The evolution of sound reception in whales is being investigated thoroughly, whereas the changes in prenatal development (ontogeny) that generate these disparate ear bone morphologies remain mostly unknown. In this study, we characterize the ontogeny of the ear bones in Cetacea by looking at the progression of ossification and associated changes in morphology using a combination of traditional measurements and an innovative landmark-free method to quantify shape on a newly assembled three-dimensional dataset spanning the ontogeny and phylogeny of extant Cetacea. We have found that the two groups of Cetacea share some aspects of ear ontogeny, such as a common growth trajectory of the periotic. However, differences in ossification, allometry and growth trajectory, particularly in the periotic bone, reflect their divergent inner ear morphology and hearing abilities.
On the extraction of purely motor EEG neural correlates during an upper limb visuomotor task
Authors: Bibián Carlos , Irastorza-Landa Nerea , Schönauer Monika , Birbaumer Niels , López-Larraz Eduardo , Ramos-Murguialday Ander 
Published: November 2021

Abstract
Deciphering and analyzing the neural correlates of different movements from the same limb using electroencephalography (EEG) would represent a notable breakthrough in the field of sensorimotor neurophysiology. Functional movements involve concurrent posture co-ordination and head and eye movements, which create electrical activity that affects EEG recordings. In this paper, we revisit the identification of brain signatures of different reaching movements using EEG and present, test, and validate a protocol to separate the effect of head and eye movements from a reaching task-related visuomotor brain activity. Ten healthy participants performed reaching movements under two different conditions: avoiding head and eye movements and moving with no constrains. Reaching movements can be identified from EEG with unconstrained eye and head movement, whereas the discriminability of the signals drops to chance level otherwise. These results show that neural patterns associated with different arm movements could only be extracted from EEG if the eye and head movements occurred concurrently with the task, polluting the recordings. Although these findings do not imply that brain correlates of reaching directions cannot be identified from EEG, they show the consequences that ignoring these events can have in any EEG study that includes a visuomotor task.