bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of Water-Based Thermal Insulation Paints Using Silica Aerogel Made From Incineration Ash
Authors: Li Xiaodong , Lu Yanru , Yin Xi Jiang , Handojo Djati Utomo 
Published: July 2021

Abstract
Building insulation plays a important role in energy consumption reduction for sustainable buildings. By applying an efficient insulation, the energy used to keep the buidling cool or warm can be saved significantly. In this work, we have developed a sustainable method for fabrication of silica aerogel (SA) micro powder from solid waste ashes collected from waste-to-energy incineration plants. The fabricated SA has a low thermal conductivity of 0.025 W/mK, high surface area of 786 m2/g and high porosity of 96.36%. It has been mixed into water-based paints to develop a high efficient thermal insulation paint with inproved thermal insulaton properties. Different percentage of SA were mixed into the paint samples to prepare the silica aerogel thermal insulation paint (SATIP) and their physical properties were studied. The SATIP samples were then coated on cement board substrates. The thermal conductivity, water resistance, and insulation performance of the samples were investigated and evaluated systematically. The thermal conductivity results demonstrate that SA additive could significantly improve the thermal insulation properties of the paint. By adding 20 vol% of SA into the SATIP, it achieves up to 12 ˚C surface temperature reduction improvement compare to the one without SA on the heated plate at 60 ˚C, and 1 ˚C in-chamber temperature reduction with external temperature of 44.6 ˚C. The results demonstrated a promising and high efficient thermal insulation paint with silica aerogel which has a great potential for application in sustainable and green buildings for energy saving.
Minocycline suppresses disease-associated microglia (DAM) in a model of photoreceptor cell degeneration
Authors: Doyle Sarah , Ozaki Ema , Delaney Conor , Campbell Matthew 
Published: July 2021

Abstract
Background: As the resident immune cells in the retina, microglia play important homeostatic roles in retinal immune regulation and neuroprotection. However, chronic microglia activation is a common hallmark of many degenerative retinal diseases. The semi-synthetic broad spectrum tetracycline antibiotic, minocycline appears to inhibit pro-inflammatory microglia which coincides with protection against photoreceptor cell degeneration. A sub-type of microglia termed disease associated microglia ( DAM) have recently been associated with a wide range of central nervous system (CNS) diseases.Methods: In this study we examine the kinetics of microglia infiltration towards the outer retina of rhodopsin knockout mice ( rho -/- ) by immunofluorescence, and undertake transcriptional and spatial localization analysis of markers for evidence of both homeostatic function and appearance of DAMs. Results: We demonstrate in the Rho-/- mice that Iba1 + and P2RY12 + microglia take on activated morphology early in disease, prior to notable photoreceptor loss and are capable of infiltrating the subretinal space. Expression of lipid processing enzyme and DAM-marker lipoprotein lipase (LPL) is primarily observed only after microglia have traversed the ONL. Administration of minocycline to Rho-/- mice induced loss of phagocytic/DAM microglia in the outer retina in vivo coinciding with photoreceptor survival and amelioration of retinal degeneration. Conclusion: Our study identifies microglial lipid processing enzyme and DAM-marker lipoprotein lipase (LPL) as a direct target of minocycline and indicates that suppression of lipid metabolism is one mechanism by which minocycline protects against inflammation induced photoreceptor cell death.
Exact recovery of sparse signals with side information
Authors: luo xiaohu , Feng Nianci , Guo Xuhui , Zhang Zili 
Published: July 2021

Abstract
Compressed sensing has captured considerable attention of researchers in the past decades. In this paper, with the aid of the powerful null space property, some deterministic

recovery conditions are established for the previous ℓ 1 -ℓ 1 and ℓ 1 -ℓ 2 methods to guarantee the exact sparse recovery when the side information of the desired signal is available. These obtained results provide a useful and necessary complement to the previous investigation of the ℓ 1 -ℓ 1 and ℓ 1 -ℓ 2 methods that are based on the statistical analysis. Moreover, one of our theoretical findings also shows that, the sharp conditions previously established for the classical ℓ 1 method remain suitable for the ℓ 1 -ℓ 1 method to guarantee the exact sparse recovery. Numerical experiments are also carried out to further verify the recovery performance of both ℓ 1 -ℓ 1 and ℓ 1 -ℓ 2 methods.
Subcutaneous Uptake on [18F]Florbetaben PET/CT: a Possible Immune-Induced Amyloid-Beta Deposition after COVID-19 Vaccination
Authors: Laudicella Riccardo , Burger Irene Andrea , Panasiti Francesco , Longo Costanza , Scalisi Salvatore , Minutoli Fabio , Baldari Sergio , Grimaldi Luigi Maria Edoardo , Alongi Pierpaolo 
Published: July 2021

Abstract
IntroductionLarge-scale worldwide COVID-19 vaccination programs are being rapidly deployed, and high-risk patients with comorbidity are now receiving the first doses of the vaccine. Physicians should be, therefore, aware of new pitfalls associated with the current pandemic vaccination program, also in case of [18F]Florbetaben PET/CT.Case PresentationWe described the first image of [18F]Florbetaben PET/CT in the evaluation of a 70-year-old male with suspicious Alzheimer disease and unclear history of heart disease. We detailed the diagnostic imaging PET/CT workup with different findings. ConclusionIn this case, [18F]Florbetaben PET/CT can demonstrate immune-induced findings associated with the current COVID-19 pandemic vaccination programs.
Application of Continuous Wavelet Transform based on Fast Fourier Transform for the Quality Analysis of Arc Welding Process
Authors: Kumar Vikas , Ghosh Subhadip , Parida Manoj Kumar , Albert Shaju K 
Published: July 2021

Abstract
SMAW (Shielded Metal Arc Welding) and GMAW (Gas Metal Arc Welding) are two of the most prominent welding processes commonly utilized in almost all types of modern industries. Among various aspects of these processes, some of the important parameters that govern the quality of the final weld product are the skill level of welders, welding consumables, and the role of shielding gases (in GMAW). Currently, the role of these parameters in determining the quality of the welded product is examined by evaluating the final weld produced and not by investigating how these factors actually affect the welding process. This is an indirect way to evaluate such welding parameters, which are both time-consuming and expensive. During the actual welding process, random variations in arc signals (voltage and current) take place. These dynamic variations are so short and rapid that ordinary ammeters and voltmeters cannot monitor the rate of such variations. However, the reliable acquisition of such variations and its subsequent analysis can provide very useful information in determining the quality of the final weld product. In this study, arc voltage and current were acquired at 100,000 samples/sec, filtered and subsequently analyzed using Continuous Wavelet Transform based on Fast Fourier Transform (CWT-FFT) technique to evaluate welding skill, welding electrodes (in SMAW process), and the effect of shielding gases (in GMAW process). Results thus obtained clearly differentiated the skill level of different trainee welders and welding electrodes in the SMAW process and the effect of shielding gases and arc current in the GMAW process. Very good correlation among the obtained results, its weld bead and weld pool images were observed. Hence, this research proposes a simple yet effective methodology to evaluate the arc welding process parameters using CWT-FFT analysis of the welding signals.
Abiotic Factors That Affect The Distribution of Aquatic Macrophytes In Shallow Lakes Located In Sibley County, Minnesota, USA: A Spatial Modeling Approach
Authors: Schmid Samuel , Wersal Ryan , Fleming Jonathan 
Published: July 2021

Abstract
Macrophytes are an integral component of lake communities, therefore understanding the factors that affect macrophyte community structure is important for conservation and management of lakes. In Sibley County, Minnesota, USA, five lakes were surveyed using the point-intercept method. At each point the presence of macrophytes were recorded, water depth was measured, and a sediment sample was collected. Sediment samples were quantified by determining soil particle size and percent organic matter. The richness of macrophytes in all lakes were modeled via generalized linear regression with six explanatory variables: water depth, distance from shore, percent sand, percent silt, percent clay, and percent sediment organic matter. If model residuals were spatially autocorrelated, then a geographically weighted regression was used. Water depth and distance from shore were negatively related to mean species richness, and silt was either negatively or positively related to species richness depending on the lake and macrophytes present. All species richness models had pseudo-R2 values between 0.25 and 0.40. Curlyleaf pondweed (Potamogeton crispus) was related to with water depth, percent silt, and percent sediment organic matter during early season surveys.
Hydroxymethylation profile of cell free DNA is a biomarker for early colorectal cancer
Authors: Walker Nicolas , Rashid Mamunur , Yu Shirong , Bignell Helen , Lumby Casper , Livi Carmen , Howell Kate , Morley David , Morganella Sandro , Barrell Daniel , Caim Shabhonam , Gosal Walraj , Fullgrabe Jens , Charlesworth Tom , Vasquez Louella , Ahdesmaki Miika , Eizenga Jordan , Prabhat Parul , Proutski Vitali , Murat-Onana Marie , Greenwood Catherine , Kirkwood Lisa , Maisuria-Armer Meeta , Li Mengjie , Coats Emma , Winfield Victoria , Macbean Lachlan , Stock Toby , Tome-Fernandez Alice , Chan Yat , Sheikh Nasir , Golder Paula , Ost Tobias , Steward Michael , Stewart Douglas , Vilella Albert , Noursalehi Mojtaba , Paten Benedict , Lucarelli Deborah , Mason Joanne , Ridge Gareth , Mellad Jason , Shirodkar Suman , Balasubramanian Shankar , Holbrook Joanna 
Published: July 2021

Abstract
Early detection of colorectal cancer (CRC) will improve survival rates. We created a classifier to detect CRC, based on 5-hydroxymethylcytosine levels in cell free DNA isolated from blood samples of 2198 individuals. Our classifier discriminated CRC samples from controls with an area under the receiver operating characteristic curve (AUC) of 90% (sensitivity was 55% at 95% specificity). Performance was similar for early stage 1 (AUC 89%) and late stage 4 CRC (AUC 94%). Performance was independent of the proportion of tumor-DNA in the cell free DNA. We expanded the classifier to include information about cell free DNA fragment size and abundance across the genome. Overall performance was similar (AUC 91%), with gains in sensitivity (63% at 95% specificity). The 5-hydroxymethylcytosine signal allows detection of CRC, even in cell free DNA samples with undetectable tumor DNA. Including 5-hydroxymethylcytosine in multi-analyte screening, will improve sensitivity for early-stage cancer.
One year of SARS-CoV-2 pandemic: comparison of infection between health care workers and general population before and after vaccination
Authors: Visci Giovanni , Zunarelli Carlotta , Violante Francesco Saverio , Boffetta Paolo 
Published: July 2021

Abstract
BackgroundThe Covid-19 pandemic in Italy has been characterized by three waves of infection during 2020. Vaccination of healthcare workers started in January 2021, earlier than that of other population groups. The main aim of this study is to compare the spread of the pandemic between HCW and the general population focusing on potential effects of the vaccination.MethodsThe study consisted of a retrospective analysis of results of RT-PCR tests performed between 6 March 2020 and 4 April 2021 among HCWs from Bologna, Italy, and those of the general population of Emilia Romagna region. We calculated the crude proportion of positive RT-PCR tests over total tests and the crude prevalence of positive test in population; then, we conducted joinpoint analyses using the Joinpoint Regression Program of the National Cancer Institute.ResultsPandemic spread among HCWs appeared earlier than in the general population, but it otherwise appeared to have comparable features. A decline in infection was apparent among HCWs after vaccination.ConclusionsSurveillance of HCWs would inform on the epidemic in the general population. The apparent effectiveness of the anti-SarsCoV2 vaccine will likely occur in the general population.
Optimized Design of an All-Optical XOR Gate with High Contrast Ratio and Ultra-Compact Dimensions
Authors: G Anagha E. , K. Jeyachitra R. 
Published: July 2021

Abstract
In this work, an optimized structure of an XOR gate working in the optical domain is put for- ward to achieve high contrast ratio and extremely compact dimensions using a photonic crystal platform. The above structure employs silicon rods in a hexagonal lattice configuration. The design works purely on linear interference effect between the incoming light signals and does not involve any non-linear materials. The Finite Difference Time Domain based simulations are utilized to study the propagation of light within the structure and the Plane Wave Expansion Method is applied to generate bandgap structure. After optimization of the various design parameters, a contrast ratio of 31.76 dB is attained by the proposed structure along with a response time of 0.46 ps and a footprint of 42.24 μm2. The device can be operated in the C Band with optimum performance at 1550 nm, which is the telecommunication wavelength. The operating bit rate for the proposed structure is 2.17 Tbps. All-optical XOR gate being a universal gate forms the building blocks of various sequential and combinational logic designs suitable for optical computing and communication applications.
Non-redundant Tunable-Q Contourlet Transform and Its Application to Image Coding
Authors: Wang Haijiang , Wang Jingpu , Yao Fuqi , Li LiHong , Yang Qinke 
Published: July 2021

Abstract
We propose a non-redundant tunable-Q contourlet transform for image coding. Existing non-redundant contourlet transforms use multiscale pyramids to iteratively decompose an image into octave frequency bands in the frequency domain. This constant low-Q transform scheme is not suitable for the coding of rich-texture images, in which there are numerous edges and thus rich intermediate- and high- frequency components in the frequency domain. By integrating a non-redundant rational-dilation wavelet transform with the directional filter bank of the contourlet, we construct a new contourlet transform scheme which is not only non-redundant but also provides a really tunable-Q transform scheme by tuning its dilation factor. Using a search algorithm based on information-maximization, one can determine the optimal-dilation-factor (or Q-pattern) for a given dataset. Based on the SPIHT coding scheme, we construct a coding algorithm using the proposed transform. Experimental results show that for texture image coding, our coding method using the optimal Q-pattern is always superior to many existing state-of-art transform coding methods in both visual assessments and quantitative evaluations, including the JPEG and JPEG2000 standards, and the coders based on the wavelet packet transform and wavelet-based contourlet packet transform.
Geospatial Assessment of Agricultural Drought Vulnerability Using Integrated Three-Dimensional Model In The Upper Dwarakeshwar River Basin In West Bengal, India
Authors: Senapati Ujjal , Das Tapan Kumar 
Published: July 2021

Abstract
It is essential to measure the degree of agricultural drought vulnerability in an underdeveloped rain-fed agro-based economy at the local, regional, and national level. Agricultural drought has become a major concern in respect to the global food crisis for investigation and development of a sustainable agricultural system that sustains the food security of a country. In this research, delineation of the agricultural drought vulnerability (ADV) status has been carried out by multidimensional mixed-method index approach using remote sensing and geographic information system. An integrated three-dimensional model has been adopted for this study. The three indices of this model are - Exposure Index (EI), Sensitivity Index (SI) and Adaptive Capacity Index (ACI). Exposure Index has been calculated using NDDI, LULC, ADI, DF, ADD and PI. Sensitivity Index has been calculated using satellite-based remote sensing factor VHI, NDWI, EVI, NDVI, VCI, NDWI, LST, and TCI. The ACI has been formed by combining the Environmental Adaptive Capacity (EAC), Social Adaptive Capacity (SAC) and Economical Adaptive Capacity (EcAC) Index. Each index has been computed by assigning the weights based on their relative importance by using the Analytic Hierarchy process (AHP) approach. Final results were classified into five vulnerability zones, e.g., very low, low, moderate, high, and very high covering an area 362.32 km2, 186.68 km2, 568.69 km2, 547.05 km2 and 266.89 km2 respectively. Finally, results have been validated with long term Aman paddy yield data (2004 to 2014) through the Yield Anomaly Index (YAI).
Public Perception and Concern Towards Solid Waste Management: A Case Study of Mangaluru City, India
Authors: Anchan Sanjith S , K Palakshappa 
Published: July 2021

Abstract
Rapid increase in Municipal Solid Waste (MSW) generation and varying characteristics is posing great threat to most of the cities across the globe. The present paper deals with evaluation of current status of Municipal Solid Waste Management System (MSWMS) in Mangaluru, and explores the perception, opinion and attitude of the citizens. In view of the present study, a feedback survey from 410 valid respondents representing separate households was collected. The statistics of the data were analyzed using SPSS and MS Excel tools. It is evident from the results that, the existing solid waste management practice does not match the anticipation of the citizens and involvement of the citizens in the solid waste management is not satisfactory. The major findings of the survey reveal that, there is a need for improvement of solid waste management of Mangaluru with active participation of citizens, policy makers and all stakeholders.
Recruitment, Adherence And Attrition Challenges In Internet-Based Prevention Programs For Eating Disorders: The Example of A Randomised Controlled Trial of ProYouth OZ
Authors: Ali Kathina , Fassnacht Daniel B. , Farrer Louise M. , Rieger Elizabeth , Moessner Markus , Bauer Stephanie , Griffiths Kathleen M. 
Published: July 2021

Abstract
Background: Growing evidence supports the effectiveness of Internet-based prevention programs for eating disorders. Peer-to-peer support has also been identified as a potentially useful component of these programs, but the adjunctive benefit of synchronous peer support has yet to be investigated. ProYouth OZ is an Internet-based prevention program for eating disorders consisting of psychoeducation, a supportive monitoring and feedback system, and synchronous peer support. The current study aimed to undertake an indicated prevention randomised controlled trial to evaluate the effectiveness of ProYouth OZ with and without peer-to-peer support in reducing disordered eating behaviours and attitudes relative to a waitlist control group.Method: In total, 50 young adults (18 to 25 years) with eating disorder symptoms were randomised to one of the three study conditions: (1) ProYouth OZ with peer-to-peer support, (2) ProYouth OZ without peer-to-peer support, and (3) a waitlist control group. Primary and secondary outcomes were assessed at three different time points.Results: Fifteen (30%) of the 50 randomised participants completed the post-intervention assessment. Due to limited outcome data, it was not possible to statistically examine between-group differences on the primary and secondary outcomes from pre- to post-intervention. However, trends in the available data suggested that peer support may be promising and warrants further investigation.Conclusion: Findings highlight the challenges of trialling Internet-based eating disorder prevention programs in the community, including the difficulty in recruiting emerging adults, maintaining program adherence and reducing attrition. Although not eligible for the current trial, the study identified a large group of emerging adults with eating disorders who were interested in an Internet-based program, suggesting a high level of unmet need. Future research on the topic of synchronous peer-to-peer support in Internet-based prevention for eating disorders is warranted. Further studies are required to identify optimal strategies for reaching this population (e.g., online vs offline) and evaluating the effectiveness of a range of strategies for promoting engagement. Finally, there is an urgent need to develop innovative widely accessible interventions for individuals who experience clinically relevant eating disorder symptomatology and choose to access help online but may not be ready or able to seek professional face-to-face treatment.Trial registration: ACTRN12615001250527, Registered 16 November 2015, https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?ACTRN=12615001250527
SIAH1-Mediated RPS3 Ubiquitination Contributes to Chemosensitivity in Epithelial Ovarian Cancer
Authors: Chen Lu , Gao Wujiang , Sha Chunli , Li Taoqiong , Lin Li , Wei Hong , Chen Qi , Xing Jie , Zhang Mengxue , Zhao Shijie , Xu Wenlin , Li Yuefeng , Zhu Xiaolan 
Published: July 2021

Abstract
Background: The E3 ligase SIAH1 is deregulated in human cancers and correlated with poor prognosis, but its contributions to chemoresistance in epithelial ovarian cancer (EOC) are not evident. Methods: SIAHI, RPS3, NF-κB (P65), FLAG and GFP protein levels were assessed by western blotting (WB) or immunohistochemistry (IHC). The mRNA levels were revealed by qRT-PCR. Colocalization of RPS3 and SIAH1 was detected by confocal microscopy and co-immunoprecipitation (CO-IP). RPS3 ubiquitination levels were detected by immunoprecipitation (IP). Cell functional experiments were performed and A2780 xenograft models were employed to expose the latent mechanisms of the SIAH1-RPS3-NF-κB axis as well as the role of SIAH1 in inhibiting chemoresistance in vitro and in vivo.Results: We show that SIAH1 is decreased in EOC tumour tissues and cell lines and negatively correlated with RPS3 level. SIAH1 overexpression suppresses tumour cell growth, colony formation, invasion, metastasis, and cisplatin resistance in vivo and in vitro. SIAH1 promoted RPS3 ubiquitination and degradation using the RING-finger domain, which was required for RPS3 localization to the cytoplasm for subsequent NF-κB inactivation, thereby conferring chemosensitivity. Moreover, ectopic expression of RPS3 or depletion of RPS3 ubiquitination mediated by SIAH1 via the K214R mutant significantly impaired cisplatin-induced tumour suppression in cells stably expressing SIAH1. Conclusions: Our findings reveal a tumour suppressor function of SIAH1 and provide evidence that the SIAH1-RPS3-NF-κB axis may act as an appealing strategy to tackle treatment resistance in EOC.